<?xml version="1.0" encoding="UTF-8"?>
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<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA99</accession>
    <name>A0A0S2DA99_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 8">Ferrochelatase</fullName>
            <ecNumber evidence="7 8">4.99.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Heme synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Protoheme ferro-lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">hemH</name>
        <name evidence="9" type="ORF">GLE_0119</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Catalyzes the ferrous insertion into protoporphyrin IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>2 H(+) + heme b = Fe(2+) + protoporphyrin IX</text>
            <dbReference type="Rhea" id="RHEA:22584"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="4.99.1.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Fe-coproporphyrin III + 2 H(+) = coproporphyrin III + Fe(2+)</text>
            <dbReference type="Rhea" id="RHEA:49572"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:68438"/>
            <dbReference type="ChEBI" id="CHEBI:131725"/>
            <dbReference type="EC" id="4.99.1.9"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="6">
            <dbReference type="Rhea" id="RHEA:49574"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="7 8">Porphyrin-containing compound metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the ferrochelatase family.</text>
    </comment>
    <dbReference type="EC" id="4.99.1.1" evidence="7 8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0119"/>
    <dbReference type="EnsemblBacteria" id="ALN55478">
        <property type="protein sequence ID" value="ALN55478"/>
        <property type="gene ID" value="GLE_0119"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0119"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.122"/>
    <dbReference type="OMA" id="LGDPYHC"/>
    <dbReference type="UniPathway" id="UPA00252">
        <property type="reaction ID" value="UER00325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004325">
        <property type="term" value="F:ferrochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00419">
        <property type="entry name" value="Ferrochelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03411">
        <property type="entry name" value="Ferrochelatase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00323">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001015">
        <property type="entry name" value="Ferrochelatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019772">
        <property type="entry name" value="Ferrochelatase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033644">
        <property type="entry name" value="Ferrochelatase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033659">
        <property type="entry name" value="Ferrochelatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11108">
        <property type="entry name" value="PTHR11108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00762">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00109">
        <property type="entry name" value="hemH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00534">
        <property type="entry name" value="FERROCHELATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 8" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="2 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="4 7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN55478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="332" mass="36427" checksum="21C744DC05D6FD4A" modified="2016-02-17" version="1">MRMPATASNDAPAADTAVVLVNLGTPDAANTAAVRRYLAEFLHDRRVVDMSRWLWCPLLHFAILPLRSGKVAHKYASVWLPEGSPLAVHTRRLAEALQRELPQLRVIHAMRYGQPSWRATLQQLREQGIKRVLALPLYPQYSTTTTASVGDVLDAAQGLDKRLVHDYHADPDWVAAVAESIRRHRAAHGPGEHLLFSFHGLPQRLAAAGDPYPRQCEASARAIAQALGLAEDAWTLSYQSRFGREPWLEPATADTLTALAARGVRQVDVVAPGFAVDCLETLEEVAMMLAEDFAARGGKLRYVPCLNESPAHAQALAGIVRRELAGWLPADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAC9</accession>
    <name>A0A0S2DAC9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">M48 family metallopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_01505</name>
        <name evidence="2" type="ORF">GLE_0116</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945808.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0116"/>
    <dbReference type="EnsemblBacteria" id="ALN55475">
        <property type="protein sequence ID" value="ALN55475"/>
        <property type="gene ID" value="GLE_0116"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0116"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.119"/>
    <dbReference type="OMA" id="IFCPNYR"/>
    <dbReference type="OrthoDB" id="1301886at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002725">
        <property type="entry name" value="YgjP-like_metallopeptidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01863">
        <property type="entry name" value="DUF45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF45" evidence="1">
        <location>
            <begin position="45"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="264" mass="30006" checksum="C6AB19C60CF00D7F" modified="2016-02-17" version="1">MTSLLRLLTGRPPAAPRTISRETVAIVLANGQRVEVLRVRDPRARRIKLSVDERGPRLTLPLRASEIAGQRFVIEHGDWLLAQLARAGTDAPGLQPHRTETLPLRGTEVPLRWQHARYLRIQTGEDAIEIAAPETVALKSLQRALRDFYEGQARADVGRWLPRYLPGLPRAPARLRYRVMSSQWGSLAPDGALSLDLSLVLAPPAAFEYVLVHELCHLIHADHSRAFWREVEQRCPQWRLQREYFRDSGRALKARLRKLIAADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAL8</accession>
    <name>A0A0S2DAL8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PKD repeat family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Trypsin-like peptidase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_01705</name>
        <name evidence="2" type="ORF">GLE_0165</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0165"/>
    <dbReference type="EnsemblBacteria" id="ALN55524">
        <property type="protein sequence ID" value="ALN55524"/>
        <property type="gene ID" value="GLE_0165"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0165"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.167"/>
    <dbReference type="OMA" id="WFNYQCA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242250" evidence="1">
        <location>
            <begin position="27"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="412" mass="42947" checksum="6453124FFDE8FDB3" modified="2016-02-17" version="1">MNHAMPKLLAPALLASALCLSLSAAAQTAPGAPAPIKIADVRAADLQLGAQPGRVGRAGVDAGAKAVEIRTPDASFIKVHFEHFSLPAGVTLEVASPDGREVYRYSADHRDGHTVAADLGEDGKTRFSAMSISGPVAVLRLVGTAREPWRKDHGVKVSRYLEGYPEDMLPELQNEGLLSTNVGAKSICGTDNKQAAACYSTSDTQAFNASKPVARAVMSGGSLCTAWRVSSQNRMFTNNHCISTAAGVAGAEFWFNYQRSSCTGAQATVTKVTGAQLLKTDVTLDYTLFTVNNFANIASFGSLGLDPRAAVANEGIFIAGHPGGRMKELSVADTQNSTGKCRVDAPSVTGNAANSDVGYYCDTEGGSSGSPVIARSSGKVLALHHFGGCFNSGAKISLIWPQVSTHFGGVIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAW0</accession>
    <name>A0A0S2DAW0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_02315</name>
        <name evidence="2" type="ORF">GLE_0300</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW24677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55658">
        <property type="protein sequence ID" value="ALN55658"/>
        <property type="gene ID" value="GLE_0300"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0300"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.297"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="69" mass="6918" checksum="93B5F13A7C92BA82" modified="2016-02-17" version="1">MRRKGHPCPYGARAHPCARPPGLQARAETHGRAQSTATATATATATATATATATATATATATAVNRAFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAW6</accession>
    <name>A0A0S2DAW6_LYSEN</name>
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        <recommendedName>
            <fullName evidence="5">Thiol:disulfide interchange protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FE772_02470</name>
        <name evidence="9" type="ORF">GLE_0333</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the thioredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945960.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0333"/>
    <dbReference type="EnsemblBacteria" id="ALN55691">
        <property type="protein sequence ID" value="ALN55691"/>
        <property type="gene ID" value="GLE_0333"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0333"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.330"/>
    <dbReference type="OMA" id="EVVEFFW"/>
    <dbReference type="OrthoDB" id="1805428at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015036">
        <property type="term" value="F:disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd03019">
        <property type="entry name" value="DsbA_DsbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023205">
        <property type="entry name" value="DsbA/DsbL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13462">
        <property type="entry name" value="Thioredoxin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001488">
        <property type="entry name" value="Tdi_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 5" id="KW-0574">Periplasm</keyword>
    <keyword evidence="4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242544" description="Thiol:disulfide interchange protein" evidence="7">
        <location>
            <begin position="21"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="8">
        <location>
            <begin position="15"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="6">
        <location>
            <begin position="62"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001488-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN55691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW24705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="218" mass="23473" checksum="D2E119BE28B1EAF9" modified="2016-02-17" version="1">MNRRLATLLLLAALPFASLAAPKAATGPAPEPGVDYVEIPGGKPFSTPAGKIEVVEVFGYTCPHCAHFEPLISKWKATLPADVNFVPLAAPWGGYWTPYAQAFYTAQSLKLLPKTHEAVFKALHEDKSLPIQNASAQEIAGFYAKYGADAGTFAATMTGKTTEQAMKRATDFIMASGIEGTPGMVVAGKYRITTQKGFDDMLRVADHLIARERAKAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB87</accession>
    <name>A0A0S2DB87_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type VI secretion lipoprotein, VC_A0113 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Type VI secretion system lipoprotein TssJ</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Type VI secretion system-associated lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tssJ</name>
        <name evidence="2" type="ORF">BV903_17550</name>
        <name evidence="3" type="ORF">FE772_03000</name>
        <name evidence="1" type="ORF">GLE_0445</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000047">
        <property type="protein sequence ID" value="OPD62607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0445"/>
    <dbReference type="EnsemblBacteria" id="ALN55803">
        <property type="protein sequence ID" value="ALN55803"/>
        <property type="gene ID" value="GLE_0445"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62607">
        <property type="protein sequence ID" value="OPD62607"/>
        <property type="gene ID" value="BV903_17550"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0445"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.443"/>
    <dbReference type="OMA" id="QRWKFAF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.4150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017734">
        <property type="entry name" value="T6SS_SciN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038706">
        <property type="entry name" value="Type_VI_SciN-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37625">
        <property type="entry name" value="PTHR37625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12790">
        <property type="entry name" value="T6SS-SciN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03352">
        <property type="entry name" value="VI_chp_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD62607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="214" mass="23018" checksum="8B59D884E9AC9F21" modified="2016-02-17" version="1">MDTPRLSRIQHGRPSRFFLVFALGFALAAGGCSAPGGVKQAMGKSMEAFGLKKPAAPDPNVEYSVPLRLYAGENLNAGAEKKSLALVVRIYQLKDIQRFEQAPFEAFLDEKREKEALGGDLIEVNEILMTPGQRHEVQQKMPGAASHLGVVALFRSPATSRWRFSFDGRKAVKDGITIGLHACAMTATDTAALTTVLSSPANSLSSTNCSKPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBH4</accession>
    <name>A0A0S2DBH4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0298</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55656">
        <property type="protein sequence ID" value="ALN55656"/>
        <property type="gene ID" value="GLE_0298"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0298"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="38" mass="3556" checksum="487217EB16EE9CA0" modified="2016-02-17" version="1">MRTPSGAGGLRLRAQRRATATATATATATAAAAAAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBR5</accession>
    <name>A0A0S2DBR5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3 4">Long-chain-fatty-acid--CoA ligase</fullName>
            <ecNumber evidence="3">6.2.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_03525</name>
        <name evidence="3" type="ORF">GLE_0561</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946126.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0561"/>
    <dbReference type="EnsemblBacteria" id="ALN55919">
        <property type="protein sequence ID" value="ALN55919"/>
        <property type="gene ID" value="GLE_0561"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0561"/>
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            <end position="464"/>
        </location>
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            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN55919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="556" mass="60560" checksum="3E54856BDC435AA3" modified="2016-02-17" version="1"> </sequence>
</entry>
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    <accession>A0A0S2DBT0</accession>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <dbReference type="EnsemblBacteria" id="ALN55990">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
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    <feature type="domain" description="PAS" evidence="9">
        <location>
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            <end position="46"/>
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        <location>
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        </location>
    </feature>
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        <location>
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            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
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            <end position="663"/>
        </location>
    </feature>
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        <location>
            <position position="601"/>
        </location>
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        <source>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN55990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="670" mass="70063" checksum="C41ADC9E030FFC55" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBX1</accession>
    <name>A0A0S2DBX1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_08255</name>
        <name evidence="3" type="ORF">FE772_03960</name>
        <name evidence="1" type="ORF">GLE_0652</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="gene ID" value="BV903_08255"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0652"/>
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    <dbReference type="OrthoDB" id="1992626at2"/>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD64406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="83" mass="9329" checksum="6C4426284EE15933" modified="2016-02-17" version="1">MTERERRKADAELVSPVGLRAGLNRAQLDALATLEQFGWRLRFVRRPMFLDPIPVVFDKGGTVFVVIESDGSLNDKPGFAIRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBX2</accession>
    <name>A0A0S2DBX2_LYSEN</name>
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        <submittedName>
            <fullName evidence="8">Peptidase, M16 family</fullName>
            <ecNumber evidence="8">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_0627</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the peptidase M16 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946172.1">
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_0627"/>
    <dbReference type="EnsemblBacteria" id="ALN55985">
        <property type="protein sequence ID" value="ALN55985"/>
        <property type="gene ID" value="GLE_0627"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0627"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.617"/>
    <dbReference type="OMA" id="EFNRGQD"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="project" value="InterPro"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
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        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="4"/>
    </dbReference>
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        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
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        <location>
            <begin position="31"/>
            <end position="1050"/>
        </location>
    </feature>
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        <location>
            <begin position="60"/>
            <end position="201"/>
        </location>
    </feature>
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        <location>
            <begin position="211"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16" evidence="6">
        <location>
            <begin position="524"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="7">
        <location>
            <begin position="678"/>
            <end position="957"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN55985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1050" mass="109137" checksum="6ABCD15F06819864" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBX5</accession>
    <name>A0A0S2DBX5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class II aldolase and adducin N-terminal domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0543</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946112.1">
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    <dbReference type="STRING" id="69.GLE_0543"/>
    <dbReference type="EnsemblBacteria" id="ALN55901">
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        <property type="gene ID" value="GLE_0543"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0543"/>
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    <dbReference type="OMA" id="MWIKASG"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF00596">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53639"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="9"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="343" mass="36519" checksum="AE93C32F0F7219BE" modified="2016-02-17" version="1">MVNADFLNDLIALSARIGADPSLVQGGGGNTSLKRGDALWVKASGTWLAHAHERDIFVPLPLAQVRDALRHDDGETRVNLLSQGLALRPSIETSLHALLPHALVVHVHSVATIAWAVRRDAQTQLAQRLDGLNWAWVPYRRPGHRLTQVVAGILNTRTPDVLVLGNHGLVVGAADRAGAEALLAEVERRLRLPQRDAPSSQPQRLAQVNDLHWAPAPLELVHALATDAQALRIAAGGVLYPDHAVFLGARAAVVNDSECLSAALARTAAECGAAPCFALVPGAGVLTAPDLSDGAQAMLHCLALVALRLDGEAALAELGESDVAELIDWEAEKYRRSLMRTPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC13</accession>
    <name>A0A0S2DC13_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HAD family hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase-like hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_03405</name>
        <name evidence="1" type="ORF">GLE_0538</name>
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    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946108.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0538"/>
    <dbReference type="EnsemblBacteria" id="ALN55896">
        <property type="protein sequence ID" value="ALN55896"/>
        <property type="gene ID" value="GLE_0538"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0538"/>
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    <dbReference type="OMA" id="ARIWMIG"/>
    <dbReference type="OrthoDB" id="1204073at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
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        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
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        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="258" mass="28847" checksum="0697765E1B123A3F" modified="2016-02-17" version="1">MTLRIHNNDKVLRAPQAIIFDTDNTLYAYDRPHSQALAAAERKAAKLLGVGADEVSGAFARAREDVKRQLGKTASSHSRLLYFQRGIEILGRKTQLVITLDLEQTYWRTFLSHCELFPGVREFLQALRSSGIGTAIITDLTSQIQFRKIIYFGLDDCFDYVVTSEEAGADKPQEAPFRLAIDKLGIDPARIWMIGDHPVNDIAGARPFGISTLLRVDRNHEGRDAGCDVEFDDFTELHQFFFSGKVDGVSQFAGAHAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC43</accession>
    <name>A0A0S2DC43_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_22575</name>
        <name evidence="4" type="ORF">FE772_04400</name>
        <name evidence="2" type="ORF">GLE_0743</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000075">
        <property type="protein sequence ID" value="OPD61682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946265.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000075.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56101">
        <property type="protein sequence ID" value="ALN56101"/>
        <property type="gene ID" value="GLE_0743"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61682">
        <property type="protein sequence ID" value="OPD61682"/>
        <property type="gene ID" value="BV903_22575"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0743"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.731"/>
    <dbReference type="OrthoDB" id="2149077at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="146" mass="16720" checksum="B39A6F54467CAC8A" modified="2016-02-17" version="1">MSNPELDRSTPEKTLHALEEAYRNGDFELALRCRNFEHEAELIQQHLRPAGAAPPAGPRGELADALQRQWRQAQPPDFLGVVTQVVAVEHFAGRFFTVTQNIRNADGRTFPQRTFMSHAEDGWAVLCPVPAYEPPQETKPWWVFWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC45</accession>
    <name>A0A0S2DC45_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0707</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946235.1">
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56065">
        <property type="protein sequence ID" value="ALN56065"/>
        <property type="gene ID" value="GLE_0707"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0707"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.695"/>
    <dbReference type="OrthoDB" id="170563at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="823" mass="88532" checksum="A7993CD289201614" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCJ6</accession>
    <name>A0A0S2DCJ6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD(P)-dependent oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Oxidoreductase, short chain dehydrogenase/reductase family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_23925</name>
        <name evidence="3" type="ORF">FE772_04980</name>
        <name evidence="1" type="ORF">GLE_0866</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000088">
        <property type="protein sequence ID" value="OPD61384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946355.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000088.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0866"/>
    <dbReference type="EnsemblBacteria" id="ALN56224">
        <property type="protein sequence ID" value="ALN56224"/>
        <property type="gene ID" value="GLE_0866"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61384">
        <property type="protein sequence ID" value="OPD61384"/>
        <property type="gene ID" value="BV903_23925"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0866"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.855"/>
    <dbReference type="OMA" id="KFGMSLC"/>
    <dbReference type="OrthoDB" id="1261526at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD61384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="271" mass="28809" checksum="08DB9EB5C3B79AA5" modified="2016-02-17" version="1">MSTLQGKTLFITGASRGIGREIALRAARDGANIAIAAKSAVANPKLPGTIHSVAAEVEAAGGRALALKCDIREEDEVNAAVAATVDAFGGLDILVNNASAIWLRGALDTPMKRFDLMQQVNARGSFLCAQACLPYLRQAANPHILTLAPPPSLDPKWWAPHTGYTLAKMGMSFVTLGLAGEFGPTGVAINALWPKTIIATDALNMIPGVPLDRCRKPQIVADAVREVLVRPAQDFYGRFLIDEDVLKEAGVSDFAQYAVEPGKPLLPDLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCS3</accession>
    <name>A0A0S2DCS3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0946</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Xanthomonadaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56304">
        <property type="protein sequence ID" value="ALN56304"/>
        <property type="gene ID" value="GLE_0946"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0946"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="49" mass="5620" checksum="94E5585E6A64B724" modified="2016-02-17" version="1">MVTFFVALDKESDPAACGRKPLMAAFRHSLPRKKQEQQQSQNGFRRSPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCV3</accession>
    <name>A0A0S2DCV3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_05580</name>
        <name evidence="2" type="ORF">GLE_0995</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56353">
        <property type="protein sequence ID" value="ALN56353"/>
        <property type="gene ID" value="GLE_0995"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0995"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.983"/>
    <dbReference type="OMA" id="VPTWTYL"/>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="16"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="185" mass="20685" checksum="777C0E3329B6D451" modified="2016-02-17" version="1">MNPDPATLPPPQGEGFVLRPWRRDDLDSLLVHADDAQVSRALSDRFPYPYTREDGERFLEGQVIDLEHPVFAIEVDGRAVGGIGAHPGRGERGHGAEFGYWLGQRLWGAGLMTRVVAAFAPWAMQRLQLYRLCAMVLDDNPASARVLLKNGFEEEGVQRCAVYKHGHVHDLRVFAKARRSLQDAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCV4</accession>
    <name>A0A0S2DCV4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HAD family hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase superfamily hydrolase, subfamily IA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_05500</name>
        <name evidence="1" type="ORF">GLE_0978</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946434.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0978"/>
    <dbReference type="EnsemblBacteria" id="ALN56336">
        <property type="protein sequence ID" value="ALN56336"/>
        <property type="gene ID" value="GLE_0978"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0978"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.966"/>
    <dbReference type="OMA" id="HHFKVIY"/>
    <dbReference type="OrthoDB" id="1484726at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="216" mass="23467" checksum="7A7D14DD0360FEB2" modified="2016-02-17" version="1">MSAQQPVLFFDLDGTLIDSSVGITRSIAYALETMRHPVPDPQALRGWIGPALRTSFQPLLGDEDKVEQAVALYLERYGREGWTEHSVYDGIAELLDGLRAAGYRMAVVTAKNENNARKILEHLPFGAHFEDIVGCTDDGRLTHKVELIGEALGRFGLTPAQCVMIGDRRMDIEGAAQHGMAGVGVLWGFGSEQELRQAGAQRIATAPAQLPELLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCW7</accession>
    <name>A0A0S2DCW7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_09610</name>
        <name evidence="5" type="ORF">D9T17_23080</name>
        <name evidence="4" type="ORF">FE772_04800</name>
        <name evidence="2" type="ORF">GLE_0826</name>
    </gene>
    <organism evidence="2 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">C3</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 9" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000021">
        <property type="protein sequence ID" value="OPD64135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000057">
        <property type="protein sequence ID" value="ROU04623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946327.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000057.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56184">
        <property type="protein sequence ID" value="ALN56184"/>
        <property type="gene ID" value="GLE_0826"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64135">
        <property type="protein sequence ID" value="OPD64135"/>
        <property type="gene ID" value="BV903_09610"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0826"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.815"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU04623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="59" mass="6063" checksum="CBB05593153CB7AA" modified="2016-02-17" version="1">MTQRSNHRQTTSKAIAASAESARAAQLRNTLLKAAPAIASIILALVLITSLTSAGVGFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCY3</accession>
    <name>A0A0S2DCY3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ser/Thr protein phosphatase family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">UDP-2,3-diacylglucosamine diphosphatase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">UDP-2,3-diacylglucosamine hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_03795</name>
        <name evidence="5" type="ORF">FE772_05805</name>
        <name evidence="3" type="ORF">GLE_1044</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallophosphoesterase superfamily. YfcE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000007">
        <property type="protein sequence ID" value="OPD65227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946484.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1044"/>
    <dbReference type="EnsemblBacteria" id="ALN56402">
        <property type="protein sequence ID" value="ALN56402"/>
        <property type="gene ID" value="GLE_1044"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65227">
        <property type="protein sequence ID" value="OPD65227"/>
        <property type="gene ID" value="BV903_03795"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1044"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1032"/>
    <dbReference type="OMA" id="YANDGDW"/>
    <dbReference type="OrthoDB" id="1690667at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043461">
        <property type="entry name" value="LpxH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34990">
        <property type="entry name" value="PTHR34990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos_2" evidence="2">
        <location>
            <begin position="15"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD65227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="277" mass="31363" checksum="0DD03131CAF6AD62" modified="2016-02-17" version="1">MSPASIVPLPLRRRAVFVSDVHLGSKHCHAAEFADFLQGLRCDKLYLVGDIVDLWWMSQRRAAWGSAQYRVVEALHALARAGTELIYVPGNHDRSIRRFCGLTLPRMQVRRRAIHLTADGRRLLVTHGDDYDAITQFGGMQEKFGDWLYERILTGNKLTNQVRRRFGKRYWSLADFLKRRSGAAERYIARFVQAGLDDARKRGLDGIVCGHIHRASLFEREGCVYANDGDWVESLTALVEDPDGTLRLLTHTGETRALLPPRAPRTLPAGKELPYAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD15</accession>
    <name>A0A0S2DD15_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aldo/keto reductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Oxidoreductase, aldo/keto reductase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_05875</name>
        <name evidence="3" type="ORF">GLE_1059</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the shaker potassium channel beta subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946496.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1059"/>
    <dbReference type="EnsemblBacteria" id="ALN56417">
        <property type="protein sequence ID" value="ALN56417"/>
        <property type="gene ID" value="GLE_1059"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1059"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1048"/>
    <dbReference type="OMA" id="EFAIAWV"/>
    <dbReference type="OrthoDB" id="1351747at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005399">
        <property type="entry name" value="K_chnl_volt-dep_bsu_KCNAB-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150">
        <property type="entry name" value="PTHR43150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01577">
        <property type="entry name" value="KCNABCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="2">
        <location>
            <begin position="16"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="321" mass="35713" checksum="DE429E7C9585D51A" modified="2016-02-17" version="1">MQYRRLGSSGLQVSALSFGAWVTFGAQIGRDTARELIAAAWDHGVNFFDNAEGYANGEAERVMGEAIAELGLPRDGYCVSSKVFFGAEAEPRPTQRGLSRKHVVEACHAALKRLRVEHLDLYFCHRPDPDTPVEETVWAMDSLVRQGKVLYWGTSEWPAALIREAHKIARAHHLQPPSMEQPQYNLLHRERVELEYAPLYAELGLGATIWSPLASGLLTGKYRAGFEGESRLGHADKEWLRRVAVGESGQRRLERVTAFVELAQELGVAPASLAIAWCLRNPHVSTAILGASRVEQLLQNLGALEVKLEDAQWQRVEAVTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD23</accession>
    <name>A0A0S2DD23_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Aminomethyltransferase</fullName>
            <ecNumber evidence="3 7">2.1.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Glycine cleavage system T protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">gcvT</name>
        <name evidence="11" type="ORF">FE772_05930</name>
        <name evidence="10" type="ORF">GLE_1072</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The glycine cleavage system catalyzes the degradation of glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>(6S)-5,6,7,8-tetrahydrofolate + (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[protein] = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16945"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10492"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="2.1.2.10"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the GcvT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.10" evidence="3 7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946504.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1072"/>
    <dbReference type="EnsemblBacteria" id="ALN56430">
        <property type="protein sequence ID" value="ALN56430"/>
        <property type="gene ID" value="GLE_1072"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1072"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1060"/>
    <dbReference type="OMA" id="MPVQYPA"/>
    <dbReference type="OrthoDB" id="282830at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004047">
        <property type="term" value="F:aminomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00259">
        <property type="entry name" value="GcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006223">
        <property type="entry name" value="GCS_T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022903">
        <property type="entry name" value="GCS_T_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028896">
        <property type="entry name" value="GCST/YgfZ/DmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013977">
        <property type="entry name" value="GCV_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCV_T_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT_dom1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757">
        <property type="entry name" value="PTHR43757"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08669">
        <property type="entry name" value="GCV_T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="SSF101790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00528">
        <property type="entry name" value="gcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GCV_T" evidence="8">
        <location>
            <begin position="7"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="GCV_T_C" evidence="9">
        <location>
            <begin position="289"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN56430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW25266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="378" mass="40880" checksum="91688AE39E7F1928" modified="2016-02-17" version="1">MSQKTILNDAHRALGAKMVDFGGWDMPISYGSQIEEHHQVRRDAGMFDVSHMTVVDLRGARVREFLRRLVANSVDKLQKSGKALYTCMLNQDGGVIDDLIVYFHDEEYFRLVVNAATRDKDLAWIGQQAAAFGVSVTERPELSMIAVQGPNAREKLIGLLREDDRARIGKLGKFVAGQAQTADGIELFVARTGYTGEDGFEVIVPEDRAVALWDALLAAGVKPAGLGARDTLRLEAGMNLYGQDMDDTVSPYEAALAWTVALDVDADGKPRDFIGRATLEAHKAGGAPRQMIGLVMDEKGVLRHGQKVLTAHGEGEILSGTFSPTLGKSIAFARVPAGEIALGAAGNVRVDIRGKEVPVRVVKFPFVRDGQAQDGVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD41</accession>
    <name>A0A0S2DD41_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gltA</name>
        <name evidence="9" type="ORF">GLE_0927</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16845"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5 8">Belongs to the citrate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0927"/>
    <dbReference type="EnsemblBacteria" id="ALN56285">
        <property type="protein sequence ID" value="ALN56285"/>
        <property type="gene ID" value="GLE_0927"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0927"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.915"/>
    <dbReference type="OMA" id="HADHEMN"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00717"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004108">
        <property type="term" value="F:citrate (Si)-synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06114">
        <property type="entry name" value="EcCS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024176">
        <property type="entry name" value="Citrate_synthase_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010953">
        <property type="entry name" value="Citrate_synthase_typ-I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001369">
        <property type="entry name" value="Citrate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="SSF48256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01798">
        <property type="entry name" value="cit_synth_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001369-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="434" mass="48333" checksum="0843B68B119C8D6E" modified="2016-02-17" version="1">MSEDSTKRLDQVNITAGDKNFALPVQHPTLGASCVDIGKLPKETGMFTYDPGFTATASCKSAITYIDGDAGVLLYRGYPIEQLAEKSNFLEVAYLLMNGELPTAGEFSKFEHEVTHHTMMHEAFRTFLYGFRHDAHPMAMLVGMLGSMASFYHNELDLEDPEQRRLAAIRLIAKVPTIAAACHRYSIGWPIRYPKNSLDYTTRFLHMLFEVPSEPLELSPVAAKAMDLLFILHADHEQNASTSTVRLVGSTGANPYVSVASGVAALWGPAHGGANEAVLKMLNEIGRPENVKSAVEKAKDKESGFRLMGFGHRVYKNYDPRAALVRKMTHDVLGELGINDPLLDVAMKLEEAALKDDYFVQRKLYPNVDFYSGIIYKALGIPVEMFTVMFAIARTAGWVSHWLEQQNDPENKIGRPRQIYTGHGVRDYVAADKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDE6</accession>
    <name>A0A0S2DDE6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Calcium-binding EF-hand-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_06455</name>
        <name evidence="4" type="ORF">GLE_1187</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56545">
        <property type="protein sequence ID" value="ALN56545"/>
        <property type="gene ID" value="GLE_1187"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1187"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1172"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="SSF47473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <source>
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    </evidence>
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        <source>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    </evidence>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
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    </evidence>
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        </source>
    </evidence>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <location>
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            <end position="18"/>
        </location>
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            <end position="622"/>
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        <location>
            <begin position="364"/>
            <end position="483"/>
        </location>
    </feature>
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        <source>
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        <source>
            <dbReference type="Pfam" id="PF01345"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN56875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="622" mass="62326" checksum="03177FEC8FDE0ADB" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE88</accession>
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        <submittedName>
            <fullName evidence="3">Lipoprotein</fullName>
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    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1460</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C40 family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ALN56817">
        <property type="protein sequence ID" value="ALN56817"/>
        <property type="gene ID" value="GLE_1460"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1460"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1441"/>
    <dbReference type="OMA" id="REMIVMR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000064">
        <property type="entry name" value="NLP_P60_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00877">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51935">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NlpC/P60" evidence="2">
        <location>
            <begin position="81"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="206" mass="21737" checksum="4CC18DC1C7D59363" modified="2016-02-17" version="1">MDCLVAAAASRQAIGVTKAAHYPGNTAPAPVRGRGPLLAAALALALCGLLAACGGGKQTVRRTPPPAQPTRVWPHVDPDNPEAANAVLMRAFSLVGTPYRYGGNTPEGGFDCSGLVNYVYRDMLALNLPRTSRDLAGYQGPRIDPLRLAAGDLVFFGSSGSVTHVGIYVGEGRFVHAPSSGGTVRLDRLDGPYWRDHYSGAKRILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEA3</accession>
    <name>A0A0S2DEA3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SMI1/KNR4 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_08290</name>
        <name evidence="1" type="ORF">GLE_1593</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946906.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56950">
        <property type="protein sequence ID" value="ALN56950"/>
        <property type="gene ID" value="GLE_1593"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1593"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1573"/>
    <dbReference type="OMA" id="TWEVSEY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037883">
        <property type="entry name" value="Knr4/Smi1-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160631">
        <property type="entry name" value="SSF160631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="114" mass="11979" checksum="03392BFF317FF1CD" modified="2016-02-17" version="1">MSEAALARVERWYGAALAAPLRAFVLAHGGREIGAVRLYPADEIVERNETYETRDYCPGYLTVGDDGGGRAVVVHAALTPPTVFVVGHGSMSKADFVAVGSGLQAWIEGGCAVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEE5</accession>
    <name>A0A0S2DEE5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Smr domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1494</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1494"/>
    <dbReference type="EnsemblBacteria" id="ALN56851">
        <property type="protein sequence ID" value="ALN56851"/>
        <property type="gene ID" value="GLE_1494"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1494"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1475"/>
    <dbReference type="OMA" id="MIKSHVN"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002625">
        <property type="entry name" value="Smr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036063">
        <property type="entry name" value="Smr_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01713">
        <property type="entry name" value="Smr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00463">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160443">
        <property type="entry name" value="SSF160443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50828">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Smr" evidence="2">
        <location>
            <begin position="103"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="196" mass="21689" checksum="8946AF1CD87670CC" modified="2016-02-17" version="1">MPMTSHPDRPEDAGDDDDAALFRAAIGEVRRLPEAALPPAAPKPRPRPRMAERDEALAREEFRHALDEQLLEAGDALSYRRDELPPKVFARLRRGEISAQEELDLHGSPVREAEALLRAFLNDARSHELGCVRIIHGKGRGGGNDFLDSRGLPVLKNLVDRMLRQRADVLAFHSAPPAQGGTGAVVVLLARPQRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEV3</accession>
    <name>A0A0S2DEV3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cyclic pyranopterin monophosphate synthase</fullName>
            <ecNumber evidence="3">4.6.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">moaC</name>
        <name evidence="6" type="ORF">GLE_1670</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:49580"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59648"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.6.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.17" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1670"/>
    <dbReference type="EnsemblBacteria" id="ALN57027">
        <property type="protein sequence ID" value="ALN57027"/>
        <property type="gene ID" value="GLE_1670"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1670"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1649"/>
    <dbReference type="OMA" id="IWDMVKS"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061799">
        <property type="term" value="F:cyclic pyranopterin monophosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01420">
        <property type="entry name" value="MoaC_PE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023045">
        <property type="entry name" value="Mo_CF_biosynth-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036522">
        <property type="entry name" value="MoaC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002820">
        <property type="entry name" value="Mopterin_CF_biosynth-C_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01967">
        <property type="entry name" value="MoaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55040">
        <property type="entry name" value="SSF55040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00581">
        <property type="entry name" value="moaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoaC" evidence="5">
        <location>
            <begin position="23"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="171" mass="17692" checksum="34A0A5DC2A099298" modified="2016-02-17" version="1">MNAKPTKAAPALTHLDRAGHPAMVDVGAKPVTARAALARCRVRFPAAVAAQLRASGMSSKKGAVIDTAIVAGTMAVKRTHELIPFCHPLPIDGCRFAVDWDGENALSIECEVRTVHRTGVEMEALTGATVAALTVYDMCKALSHAIVIGPAKLVGKRGGKRDFGAVAGAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFE1</accession>
    <name>A0A0S2DFE1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histidine--tRNA ligase</fullName>
            <ecNumber evidence="10">6.1.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Histidyl-tRNA synthetase</fullName>
            <shortName evidence="10">HisRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 12" type="primary">hisS</name>
        <name evidence="13" type="ORF">FE772_09670</name>
        <name evidence="12" type="ORF">GLE_1891</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">C3</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + L-histidine + tRNA(His) = AMP + diphosphate + H(+) + L-histidyl-tRNA(His)</text>
            <dbReference type="Rhea" id="RHEA:17313"/>
            <dbReference type="Rhea" id="RHEA-COMP:9665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9689"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78527"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.21"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.21" evidence="10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1891"/>
    <dbReference type="EnsemblBacteria" id="ALN57242">
        <property type="protein sequence ID" value="ALN57242"/>
        <property type="gene ID" value="GLE_1891"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1891"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1860"/>
    <dbReference type="OMA" id="CDFDFIG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004821">
        <property type="term" value="F:histidine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006427">
        <property type="term" value="P:histidyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00773">
        <property type="entry name" value="HisRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HisRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00127">
        <property type="entry name" value="His_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
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        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
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        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015807">
        <property type="entry name" value="His-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004516">
        <property type="entry name" value="HisRS/HisZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033656">
        <property type="entry name" value="HisRS_anticodon"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001549">
        <property type="entry name" value="His-tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="hisS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
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    <keyword evidence="5 10 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="22"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00127"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN57242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW25894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="462" mass="51578" checksum="50CE0C92B90A6B61" modified="2016-02-17" version="1">MIKPRTPPGVMELLPRDQIAFQRMLDTIRRNFERFGFLPVETPVMELTEVLLTKSGGETERQVYFVESTGARANNAQEGDARGTPELALRFDLTVPLARYVAEHEAELAFPFRRYQMQRVYRGERQQRGRYREFYQCDIDVIGKDSLSVRYDAELPACIYAVFSELDIGAFTIQLNNRKLLRGFFEAQGVADGELQALVLREVDKLDKRGADYVRETLTGEGFGLSAQAVATILGFVETRSTSHADALAKLAALGEGNDSLRQGLAELREVLELIRALGVPEANYALNFSIARGLDYYTGTVYETTLNDYPQLGSICSGGRYEDLASHYTKSKLPGVGISIGLTRLFWQLQEAKLVSTADSSVQVLITQMDDAQLPQCLALASELRAGGLNTEVVMEPSKLGKQFKYADRAGIRFVVVLGENEIAKGTATVKDLRREDQFEVARGELARTLRVELEQSRVMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFZ4</accession>
    <name>A0A0S2DFZ4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1926</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57277">
        <property type="protein sequence ID" value="ALN57277"/>
        <property type="gene ID" value="GLE_1926"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1926"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1892"/>
    <dbReference type="OMA" id="DAHVSQW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595507" evidence="1">
        <location>
            <begin position="29"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="139" mass="15024" checksum="9B7E93B6F774BB2A" modified="2016-02-17" version="1">MRTDPARTAATALRAAALLSAGAAMALAAACSRPGAGATNETAAAAKCEIPQWLQPPHGDGFCDLPADLRGFVAEYEEFKAFSGGEPSDAAAMEALAREHERRVGEQRARWSRLRARYAADTAVSRWIQRYGQEQDRFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG94</accession>
    <name>A0A0S2DG94_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Heat-inducible transcription repressor HrcA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">hrcA</name>
        <name evidence="9" type="ORF">FE772_11240</name>
        <name evidence="8" type="ORF">GLE_2230</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the HrcA family.</text>
    </comment>
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        <property type="protein sequence ID" value="ALN57579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947382.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2230"/>
    <dbReference type="EnsemblBacteria" id="ALN57579">
        <property type="protein sequence ID" value="ALN57579"/>
        <property type="gene ID" value="GLE_2230"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2230"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2195"/>
    <dbReference type="OMA" id="DYPGTMG"/>
    <dbReference type="OrthoDB" id="1510750at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00081">
        <property type="entry name" value="HrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002571">
        <property type="entry name" value="HrcA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021153">
        <property type="entry name" value="HrcA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023120">
        <property type="entry name" value="WHTH_transcript_rep_HrcA_IDD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34824">
        <property type="entry name" value="PTHR34824"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01628">
        <property type="entry name" value="HrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005485">
        <property type="entry name" value="HrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00331">
        <property type="entry name" value="hrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0678">Repressor</keyword>
    <keyword evidence="3 5" id="KW-0346">Stress response</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HrcA" evidence="7">
        <location>
            <begin position="112"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="201"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN57579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW26158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="355" mass="38359" checksum="585A1A6E921F1D8E" modified="2016-02-17" version="1">MNRRANDPALDPRARQLLRALIGRYIHSGEPVGSQTLARHAGLDVSAATIRNILSDLEEAGLLSAPHTSAGRIPTAQGYRLFVDSLLQVRPLPEGEVARLRSELPPGSGTQALLGSASELLSAMTHFVGVVSVPKREQFAFRRIEFVPLDAQRVLAILVFADQEVQNRIIQTRRPFEAGELERVGNYLNTHFAGRPVAEIRASLLLELRNAQSEMQALLAQSMELAEQALAPDGDDMVLAGQTRLMGVQELADLDRLRELFEAFARKREILQLLERTVRAPGMRIFIGEETGLAPLEGVSLVTAPYGAGGRVLGVLGVIGPTRMAYERVIPVVQAAADALGDAFLAGEGAVGEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGC9</accession>
    <name>A0A0S2DGC9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_11650</name>
        <name evidence="2" type="ORF">GLE_2322</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947450.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57671">
        <property type="protein sequence ID" value="ALN57671"/>
        <property type="gene ID" value="GLE_2322"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2322"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2287"/>
    <dbReference type="OrthoDB" id="2139795at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033243126" evidence="1">
        <location>
            <begin position="30"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="236" mass="25230" checksum="1A13D9E24DC08EC1" modified="2016-02-17" version="1">MSLRPFPPRSFRRALAALTLLLAAGGAQAACPDGSPCETIAVYRVQTWPALLTDAAGRDSLSLQEANGTSQASFEPVIKGYAGGPKTLAIRFSVIRIASAPNAYCNCNFELGDKACKTSDLDLLKQCKRVCLNSGKTCTATGKDDKSDGGAWYAFPASTRCVTRDAAPTQQWKKNAFEVNPKNCDWYQASSSIKRAACVADALKLDPSLDLDRLFANEAPCATVDAATLQQEAIPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGG8</accession>
    <name>A0A0S2DGG8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57359">
        <property type="protein sequence ID" value="ALN57359"/>
        <property type="gene ID" value="GLE_2009"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2009"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1975"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025975">
        <property type="entry name" value="Polysacc_lyase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01345">
        <property type="entry name" value="DUF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14099">
        <property type="entry name" value="Polysacc_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF11" evidence="1">
        <location>
            <begin position="392"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="476" mass="49179" checksum="4A106A1D3E6CDD6A" modified="2016-02-17" version="1">MFALALACASAHAQTPLLRVDYETGTIDSGIPDLNTSDASAADAIFVSETARAGRYAIAHKVVLDDLAYVSEGKPRSESAGLRTLPARYRSGDHRRYAFSVMLKDWEDYTAGRIASVDIVWQFKHTQGGADMFVGVRRNQLVLRYANTQSVLINDIRPYDNAWIDLRFDVLWADTPTGYFTADLRLPGESGFTRRAAVAGIVTLDPTATGAFGYPKWGLYRPDSDSSRGSAITRIALHDEISVVALPAARIRLNKAFAPSGRAGDGDQFALSIAPPAPAGTVSATTTGSGAQVTSPPALLVAANGGGTYVLSETAAASAPGTDLGRYRSAYACTNARAGGQAPRGDGASFALALADEDDLSCTFTNTRANTSDLAIAVTNTPAQGPGDQPDDNVLAGTVSTYRIQVSNHGPDAATGAIVRDAALAGLACADPVACAGAACPAATVAVADLMGAGVTLGELAGGASVSLDVSCRVAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGM7</accession>
    <name>A0A0S2DGM7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2324</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57673">
        <property type="protein sequence ID" value="ALN57673"/>
        <property type="gene ID" value="GLE_2324"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2324"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2289"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="70" mass="7583" checksum="29C77A816B86A20F" modified="2016-02-17" version="1">MKHALIEDGLALSADGRLSLSDAGNTLLQALQHMVWAEVESLQQVLVNKSSAPSDEVLRMTRLPASNQPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGP4</accession>
    <name>A0A0S2DGP4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2357</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57706">
        <property type="protein sequence ID" value="ALN57706"/>
        <property type="gene ID" value="GLE_2357"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2357"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2318"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="58" mass="6716" checksum="B6ED2DCB7C041AE9" modified="2016-02-17" version="1">MSIQRKRIVFAFMFALTNAAQRCMRLRPIAATQRDCAHPRRAASHRLPPRRNCVAVPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGP7</accession>
    <name>A0A0S2DGP7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2481</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947570.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2481"/>
    <dbReference type="EnsemblBacteria" id="ALN57830">
        <property type="protein sequence ID" value="ALN57830"/>
        <property type="gene ID" value="GLE_2481"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2481"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2443"/>
    <dbReference type="OMA" id="IWEGVTQ"/>
    <dbReference type="OrthoDB" id="1889889at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007213">
        <property type="entry name" value="Ppm1/Ppm2/Tcmp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04072">
        <property type="entry name" value="LCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="289" mass="31325" checksum="9D4E9E90CDEB44E1" modified="2016-02-17" version="1">MDRVSTSMLLAAAAVRQARSDSDPAVARNAALARACLQGCGRPGARLLCAVDHALGRVLLAALETLYLPGIGAHYAWRKRRIRRWALQACGDGARQLLVLGAGFDGLSLFLLERIPGLRAFEIERESTVAIKREALCWLGVREPRLSLIAADLSVVAIEALLPGIPRFDPRQPTLVVAEGVLMYLEPPELQRLLRGLARTLPGAGLIATAMAPAAAGTPGFARQRPWVRRWLKRAGEPFRWAQTRDALAATLAAASVRLERIADPDEAADPDPCPGEWLFAGEFARPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGT1</accession>
    <name>A0A0S2DGT1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lanthionine synthetase C-like protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Type 2 lantipeptide synthetase LanM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">lanM</name>
        <name evidence="4" type="ORF">FE772_12185</name>
        <name evidence="3" type="ORF">GLE_2438</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947539.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2438"/>
    <dbReference type="EnsemblBacteria" id="ALN57787">
        <property type="protein sequence ID" value="ALN57787"/>
        <property type="gene ID" value="GLE_2438"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2438"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2400"/>
    <dbReference type="OrthoDB" id="50133at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04792">
        <property type="entry name" value="LanM-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007822">
        <property type="entry name" value="LANC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025410">
        <property type="entry name" value="Lant_dehyd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017146">
        <property type="entry name" value="Lanti_2_LanM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13575">
        <property type="entry name" value="DUF4135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05147">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037228">
        <property type="entry name" value="Lant_mod_RumM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01260">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03897">
        <property type="entry name" value="lanti_2_LanM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4135" evidence="2">
        <location>
            <begin position="106"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="510"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="938" mass="101335" checksum="C865663B7812C2B5" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHA3</accession>
    <name>A0A0S2DHA3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_12365</name>
        <name evidence="1" type="ORF">GLE_2475</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947564.1">
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_2475"/>
    <dbReference type="EnsemblBacteria" id="ALN57824">
        <property type="protein sequence ID" value="ALN57824"/>
        <property type="gene ID" value="GLE_2475"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2475"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2437"/>
    <dbReference type="OMA" id="KDEDHHL"/>
    <dbReference type="OrthoDB" id="1327610at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="205" mass="22830" checksum="B8F23B53BEA349E1" modified="2016-02-17" version="1">MASKRHDRAQLHELLYQALETEKGGIRIYQTALECAVNEGLREEWQGYLQETRRHHEILVGVFAELGLDPQAASPGREVVAHIGASLVKAMQMAIKAGDPQAAELVAAECVVLAETKDHQNWELIGHVAKNTSGKEAATLMGAYEQVEKEEDHHLYHTQGWGRELWIASLGFKAVLPPPEEIKHVETAIGASRAEQSRERMLKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHE0</accession>
    <name>A0A0S2DHE0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ABC transporter permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_01675</name>
        <name evidence="4" type="ORF">FE772_12690</name>
        <name evidence="2" type="ORF">GLE_2527</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD65731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947609.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2527"/>
    <dbReference type="EnsemblBacteria" id="ALN57876">
        <property type="protein sequence ID" value="ALN57876"/>
        <property type="gene ID" value="GLE_2527"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65731">
        <property type="protein sequence ID" value="OPD65731"/>
        <property type="gene ID" value="BV903_01675"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2527"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2489"/>
    <dbReference type="OMA" id="KPADAQF"/>
    <dbReference type="OrthoDB" id="1552415at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010390">
        <property type="entry name" value="DUF990"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06182">
        <property type="entry name" value="ABC2_membrane_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD65731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="270" mass="29493" checksum="E317F77C97F4395E" modified="2016-02-17" version="1">MLGELLRHLRIYGVLLRNSFMVQMEYRFNFYAGLVMETGFLLSKLAYAYVIVSADVDFGGLRPSEALVVLGCYTLLTGFYTCFFMANNFELSAKIRNGDLDLVLVKPASGLFLVSCARAEFSLLLPNAIAGIAMIVYGAQLSDVPLSAATVAATLVALGLSLSVAYAIMILPQFLAFWFGTTHAVTQLSHSLWDLNTVPAAAFARGVRLFGTFALPIFMVTNYPAYLLLGKLPAHGYLWLLAAPVVWLGLTVALWRFALRAYSSASGWSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHG7</accession>
    <name>A0A0S2DHG7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3247 domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">DUF3247 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_02105</name>
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        <name evidence="1" type="ORF">GLE_2362</name>
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    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000004">
        <property type="protein sequence ID" value="OPD65579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW26255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947479.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57711">
        <property type="protein sequence ID" value="ALN57711"/>
        <property type="gene ID" value="GLE_2362"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD65579"/>
        <property type="gene ID" value="BV903_02105"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2362"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2323"/>
    <dbReference type="OMA" id="APHVYSE"/>
    <dbReference type="OrthoDB" id="2015816at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021649">
        <property type="entry name" value="DUF3247"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11607">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD65579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="100" mass="11460" checksum="A17027C3206CDE8C" modified="2016-02-17" version="1">MTKLADRVYRDPADLRRLTALVEQLPDEGLVDLQLVDGSWRAAVVTTRPSLQTFLDRDGREGINAVVRIDDPRTGRSDYLWIDELAQVRPIHSAQRRFTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHT3</accession>
    <name>A0A0S2DHT3_LYSEN</name>
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        <submittedName>
            <fullName evidence="1">Endoribonuclease L-PSP family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">RidA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_14465</name>
        <name evidence="1" type="ORF">GLE_2899</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
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            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2899"/>
    <dbReference type="EnsemblBacteria" id="ALN58247">
        <property type="protein sequence ID" value="ALN58247"/>
        <property type="gene ID" value="GLE_2899"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2899"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2861"/>
    <dbReference type="OMA" id="QCWANVE"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="126" mass="14681" checksum="B3076EDBB9D98938" modified="2016-02-17" version="1">MHMQMQRRAIQPNDVSYAQAHEISGFRRLLFISGQLPQCEKCILPKDFEGQCRRAWANVEQQLKQAGMDFSNLVKVTTFLSERRLRERNYEIRREVLGEHTPALTVIIADLYEEGWMVEIEAIAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHW7</accession>
    <name>A0A0S2DHW7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glucokinase</fullName>
            <ecNumber evidence="1">2.7.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Glucose kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 3" type="primary">glk</name>
        <name evidence="4" type="ORF">BV903_06025</name>
        <name evidence="5" type="ORF">FE772_13865</name>
        <name evidence="3" type="ORF">GLE_2776</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + D-glucose = ADP + D-glucose 6-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17825"/>
            <dbReference type="ChEBI" id="CHEBI:4167"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the bacterial glucokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.2" evidence="1"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000011">
        <property type="protein sequence ID" value="OPD64769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947806.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000011.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2776"/>
    <dbReference type="EnsemblBacteria" id="ALN58124">
        <property type="protein sequence ID" value="ALN58124"/>
        <property type="gene ID" value="GLE_2776"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64769">
        <property type="protein sequence ID" value="OPD64769"/>
        <property type="gene ID" value="BV903_06025"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2776"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2733"/>
    <dbReference type="OMA" id="NNHWRLS"/>
    <dbReference type="OrthoDB" id="992687at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004340">
        <property type="term" value="F:glucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005536">
        <property type="term" value="F:glucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00524">
        <property type="entry name" value="Glucokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003836">
        <property type="entry name" value="Glucokinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02685">
        <property type="entry name" value="Glucokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00749">
        <property type="entry name" value="glk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="1 3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="7"/>
            <end position="12"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD64769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="329" mass="34398" checksum="B8A928AC046D8D93" modified="2016-02-17" version="1">MTGALLADIGGTNARFALAASDPSAPALLPDSVQVYAVADFPSLADAARHYLDKVGAAPSHGVFAVAGRVDGDEARITNHPWVISAERTRIALGLTRIDLVNDFAAQAMAVSLLGVGDVVPIGGVRWHGWNDSGDRTYAIIGPGTGLGVGALLRRDGRFYPLQTEGGHVSFAPNNPEEIDVLKRLSGEFGRVSNERLISGSGLVNLHRALSQIAGEDPGPLQPQDITAMAREGDVRCLRAIDVFCAVFGAAAGDLVLTLGAWDGVFLPGGLVPKLMPWLAHSGFRQRFEHKGRFSPTMARVPTLAVTHPQPGLLGAAALAAQCALKAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI28</accession>
    <name>A0A0S2DI28_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD(P)H-dependent oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">NADPH-dependent FMN reductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_13680</name>
        <name evidence="2" type="ORF">GLE_2734</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947774.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2734"/>
    <dbReference type="EnsemblBacteria" id="ALN58082">
        <property type="protein sequence ID" value="ALN58082"/>
        <property type="gene ID" value="GLE_2734"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2734"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2692"/>
    <dbReference type="OMA" id="VYPLWWM"/>
    <dbReference type="OrthoDB" id="1143659at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003680">
        <property type="entry name" value="Flavodoxin_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02525">
        <property type="entry name" value="Flavodoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin_2" evidence="1">
        <location>
            <begin position="1"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="200" mass="21615" checksum="687EDA046C7B2094" modified="2016-02-17" version="1">MHVLIVLAHPAADSLTHAVAAQVGEGARAAGHSVELADLAAEGFDPRYGQADHDAYRGRAPLPADVLAEQARIERADAVVLVYPVYWWSMPALLKGWIDRTFANGWAYATQDGRVTGRLQRLRVHLLGLGGADERTYLKHAYDVAMKTQIDHGIFDYCGACVAGSTFRFDTEERDATAHLAAAFELGRGVFVEGAHCAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI32</accession>
    <name>A0A0S2DI32_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">VirB3 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">virB3</name>
        <name evidence="2" type="ORF">GLE_2816</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2816"/>
    <dbReference type="EnsemblBacteria" id="ALN58164">
        <property type="protein sequence ID" value="ALN58164"/>
        <property type="gene ID" value="GLE_2816"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2816"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2773"/>
    <dbReference type="OMA" id="WIDTKFR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007792">
        <property type="entry name" value="T4SS_VirB3/TrbD/AvhB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05101">
        <property type="entry name" value="VirB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="88" mass="10542" checksum="70948E6108BB862B" modified="2016-02-17" version="1">MFLGVPYIPFTFGAGACLLLTFYVDMFCILLLPIVIFIMRQMARRDEMIFRLLGLRLQFRMRMRNLQQHQGMWVFTPNYYRSPGDKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DID8</accession>
    <name>A0A0S2DID8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58298">
        <property type="protein sequence ID" value="ALN58298"/>
        <property type="gene ID" value="GLE_2950"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2950"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2912"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046116">
        <property type="entry name" value="DUF6053"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19523">
        <property type="entry name" value="DUF6053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="40" mass="3828" checksum="5FF3BBD1DA24EBA3" modified="2016-02-17" version="1">MGGPSGPTLSGPVAVSWNKSIGPEGPPTHTQAVRGSGGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIH6</accession>
    <name>A0A0S2DIH6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Linear gramicidin synthetase subunit D</fullName>
            <ecNumber evidence="8">1.-.-.-</ecNumber>
            <ecNumber evidence="8">5.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_2959</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="8"/>
    <dbReference type="EC" id="5.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947939.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2959"/>
    <dbReference type="EnsemblBacteria" id="ALN58307">
        <property type="protein sequence ID" value="ALN58307"/>
        <property type="gene ID" value="GLE_2959"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2959"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2920"/>
    <dbReference type="OMA" id="PAYVKWI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="Far_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010080">
        <property type="entry name" value="Thioester_reductase-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01746">
        <property type="entry name" value="Thioester-redct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 5" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="1051"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1029"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1036"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="5">
        <location>
            <position position="1089"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1535" mass="165407" checksum="825F07F2CCBC5053" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIJ1</accession>
    <name>A0A0S2DIJ1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Dual-specificity RNA methyltransferase RlmN</fullName>
            <ecNumber evidence="14">2.1.1.192</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">23S rRNA (adenine(2503)-C(2))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">23S rRNA m2A2503 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Ribosomal RNA large subunit methyltransferase N</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">tRNA (adenine(37)-C(2))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">tRNA m2A37 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">rlmN</name>
        <name evidence="17" type="ORF">GLE_2910</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>adenosine(2503) in 23S rRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(2503) in 23S rRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42916"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10152"/>
            <dbReference type="Rhea" id="RHEA-COMP:10282"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74497"/>
            <dbReference type="EC" id="2.1.1.192"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>adenosine(37) in tRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(37) in tRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43332"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10485"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74497"/>
            <dbReference type="EC" id="2.1.1.192"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="14">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="14">Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the radical SAM superfamily. RlmN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.192" evidence="14"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2910"/>
    <dbReference type="EnsemblBacteria" id="ALN58258">
        <property type="protein sequence ID" value="ALN58258"/>
        <property type="gene ID" value="GLE_2910"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2910"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2872"/>
    <dbReference type="OMA" id="QVGCSLD"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070040">
        <property type="term" value="F:rRNA (adenine-C2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002935">
        <property type="term" value="F:tRNA (adenine-C2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01849">
        <property type="entry name" value="RNA_methyltr_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040072">
        <property type="entry name" value="Methyltransferase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027492">
        <property type="entry name" value="RNA_MTrfase_RlmN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004383">
        <property type="entry name" value="rRNA_lsu_MTrfase_RlmN/Cfr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30544">
        <property type="entry name" value="PTHR30544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006004">
        <property type="entry name" value="CHP00048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00275">
        <property type="entry name" value="adenosine_C2_methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00048">
        <property type="entry name" value="rRNA_mod_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 14" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13 14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12 14" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 14" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="8 14" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 14" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Radical SAM core" evidence="16">
        <location>
            <begin position="152"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="14">
        <location>
            <begin position="219"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="14">
        <location>
            <begin position="273"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="422"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="14">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="active site" description="S-methylcysteine intermediate" evidence="14">
        <location>
            <position position="401"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="358"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ALN58258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="441" mass="48576" checksum="AB568BA7836E74E1" modified="2016-02-17" version="1">MNEIRDNIDAPSAADAQAEGKTRIDAERVDAAADAVAAVPATAAAKPVAAVPDNGKTNLFDLDRTQLEDFFEHSLGEKRYRAHQVMKWIHHRYVTDFDGMTDLGKALRAKLEAHAQVRAPMVVFDKPSTDGTHKWLLGMDPKNAIETVYIPDKGRGTLCVSSQVGCALNCQFCSTATQGFNRNLSTAEIIGQVWVAARHLGNVPHQQRRLTNVVMMGMGEPLANFDNVVRAMSIMRDDLGYGLANKRVTLSTAGMVPMIDKLGEVSDVSLAVSLHAPNDELRSELVPLNKKYPIAELMESCVRYALRKRGTSVTFEYTLMKGVNDQPTHARQLVRLLRQFDNAVQMKDAAKVNLIPFNPFPGTRFERPDDAAIRAFQKLLNEAGMIAPVRRTRGDDIDAACGQLKGQVMDRTRRQAEFRKRLQAQGLDQGPGRGGEIGDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIS2</accession>
    <name>A0A0S2DIS2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_09250</name>
        <name evidence="1" type="ORF">GLE_3204</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000020">
        <property type="protein sequence ID" value="OPD64225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58550">
        <property type="protein sequence ID" value="ALN58550"/>
        <property type="gene ID" value="GLE_3204"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64225">
        <property type="protein sequence ID" value="OPD64225"/>
        <property type="gene ID" value="BV903_09250"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3204"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3159"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD64225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="74" mass="7569" checksum="1F62D46E54233690" modified="2016-02-17" version="1">MACVRLYDRRGFARECAAVPAAEAALRGLGETISAALARENPTPAPATARQRTAASTDNLALGATISASAIRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIS6</accession>
    <name>A0A0S2DIS6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3072</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58419">
        <property type="protein sequence ID" value="ALN58419"/>
        <property type="gene ID" value="GLE_3072"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3072"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3032"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="52" mass="5365" checksum="2C961A9882D89CB0" modified="2016-02-17" version="1">MPRPGAPRGARSYLTRASAGRDLSVTTAQMFETATTRMKAARAASSPAATAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIW2</accession>
    <name>A0A0S2DIW2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 6">50S ribosomal protein L19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rplS</name>
        <name evidence="8" type="ORF">BV903_24635</name>
        <name evidence="10" type="ORF">D9T17_11935</name>
        <name evidence="9" type="ORF">FE772_16110</name>
        <name evidence="7" type="ORF">GLE_3252</name>
    </gene>
    <organism evidence="7 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 11">C3</strain>
        </source>
    </reference>
    <reference evidence="8 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">OH11</strain>
        </source>
    </reference>
    <reference evidence="9 14" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the bacterial ribosomal protein bL19 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000096">
        <property type="protein sequence ID" value="OPD61262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000029">
        <property type="protein sequence ID" value="ROU06818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948153.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000029.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3252"/>
    <dbReference type="EnsemblBacteria" id="ALN58598">
        <property type="protein sequence ID" value="ALN58598"/>
        <property type="gene ID" value="GLE_3252"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61262">
        <property type="protein sequence ID" value="OPD61262"/>
        <property type="gene ID" value="BV903_24635"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3252"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3206"/>
    <dbReference type="OMA" id="TITVYYE"/>
    <dbReference type="OrthoDB" id="1698718at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00402">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038657">
        <property type="entry name" value="L19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001857">
        <property type="entry name" value="Ribosomal_L19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018257">
        <property type="entry name" value="Ribosomal_L19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15680">
        <property type="entry name" value="PTHR15680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01245">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002191">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00061">
        <property type="entry name" value="RIBOSOMALL19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01024">
        <property type="entry name" value="rplS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01015">
        <property type="entry name" value="RIBOSOMAL_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD61262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW26932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROU06818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="132" mass="14679" checksum="428FD03B6F24C5BC" modified="2016-02-17" version="1">MNKPSIHTLVQNFEAEQVQRKLPEFSPGDTVVVNVKVKEGNRERVQAYEGVVIGKKNAGLNSSFTVRKISHGYGVERVFQTHSAVIDSVQVKRRGKVRAGKLYYLRGLEGKKARIKEDLAAYARAKNAPAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIY4</accession>
    <name>A0A0S2DIY4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF1249 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_14370</name>
        <name evidence="2" type="ORF">GLE_2875</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2875"/>
    <dbReference type="EnsemblBacteria" id="ALN58223">
        <property type="protein sequence ID" value="ALN58223"/>
        <property type="gene ID" value="GLE_2875"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2875"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2837"/>
    <dbReference type="OMA" id="ATHCYVG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009659">
        <property type="entry name" value="DUF1249"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38774">
        <property type="entry name" value="PTHR38774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06853">
        <property type="entry name" value="DUF1249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="183" mass="20738" checksum="2278D410BBB163D8" modified="2016-02-17" version="1">MTQAASRFARIPKLSRFGWLMGLYAENHERLTRMFEPAGLARGTYLSQVGDGLDLRLDVLEQHRYTTELRLTYAMQDPLTGEPDPSAYVRLYHDAHQVEATHCYVGRRWQDAIGMYPPPAQVLGHRMRMNTFLGKWLEYLAERGHGMTRLRPVELDPSPSDPNEDDPRGAGHDGAAKNSAMNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ09</accession>
    <name>A0A0S2DJ09_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Potassium-transporting ATPase potassium-binding subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP phosphohydrolase [potassium-transporting] A chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Potassium-binding and translocating subunit A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Potassium-translocating ATPase A chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 10" type="primary">kdpA</name>
        <name evidence="10" type="ORF">GLE_3192</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">The system is composed of three essential subunits: KdpA, KdpB and KdpC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the KdpA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3192"/>
    <dbReference type="EnsemblBacteria" id="ALN58538">
        <property type="protein sequence ID" value="ALN58538"/>
        <property type="gene ID" value="GLE_3192"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3192"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3147"/>
    <dbReference type="OMA" id="LMMWTEF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008556">
        <property type="term" value="F:P-type potassium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00275">
        <property type="entry name" value="KdpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004623">
        <property type="entry name" value="KdpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30607">
        <property type="entry name" value="PTHR30607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03814">
        <property type="entry name" value="KdpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001294">
        <property type="entry name" value="K_ATPaseA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00680">
        <property type="entry name" value="kdpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0630">Potassium</keyword>
    <keyword evidence="3 9" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="71"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="200"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="391"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="436"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="498"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="546"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN58538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="582" mass="62008" checksum="4528823AEE5A52EB" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ41</accession>
    <name>A0A0S2DJ41_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6484 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_16480</name>
        <name evidence="2" type="ORF">GLE_3332</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948217.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3332"/>
    <dbReference type="EnsemblBacteria" id="ALN58678">
        <property type="protein sequence ID" value="ALN58678"/>
        <property type="gene ID" value="GLE_3332"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3332"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3282"/>
    <dbReference type="OMA" id="RCGKATI"/>
    <dbReference type="OrthoDB" id="1728259at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045506">
        <property type="entry name" value="DUF6484"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20093">
        <property type="entry name" value="DUF6484"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6484" evidence="1">
        <location>
            <begin position="39"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="160" mass="16943" checksum="287571023B50DFE0" modified="2016-02-17" version="1">MEEKSSPAFGIEPEYDADTASPLLAATAPAPLPAGAIVVGRVARVDADKTVWVAHAALPGRIQPARCAIEVHEEYAGREVVLAFEHCDPRRPIVLGLVWQPEAAAPLERVEICAGQEVVVRCGEASVTLTADGKILLRGAYISSHAKGTNRLKGGSVRMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ44</accession>
    <name>A0A0S2DJ44_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_09175</name>
        <name evidence="2" type="ORF">GLE_3224</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000020">
        <property type="protein sequence ID" value="OPD64212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948135.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000020.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58570">
        <property type="protein sequence ID" value="ALN58570"/>
        <property type="gene ID" value="GLE_3224"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64212">
        <property type="protein sequence ID" value="OPD64212"/>
        <property type="gene ID" value="BV903_09175"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3224"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3178"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595679" evidence="1">
        <location>
            <begin position="28"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="93" mass="8883" checksum="4291499A218DA7A7" modified="2016-02-17" version="1">MKTTLGVALTPPSAAALIAGACLLAAACLPTCHGRDYARASAAAPAASPCAATAGPARAIAADALDEAAEAAQAARYPPGAAQMQGHAASGQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJK0</accession>
    <name>A0A0S2DJK0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">zf-CGNR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3342</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3342"/>
    <dbReference type="EnsemblBacteria" id="ALN58688">
        <property type="protein sequence ID" value="ALN58688"/>
        <property type="gene ID" value="GLE_3342"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3342"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3292"/>
    <dbReference type="OMA" id="ETHECSW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010852">
        <property type="entry name" value="ABATE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023286">
        <property type="entry name" value="ABATE_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021005">
        <property type="entry name" value="Znf_CGNR"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07336">
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    </dbReference>
    <dbReference type="Pfam" id="PF11706">
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF160904">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-CGNR" evidence="1">
        <location>
            <begin position="175"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="220" mass="24256" checksum="4B508352E88B7CD0" modified="2016-02-17" version="1">MADYHNLQNVFKGFSMRLEHHQFRDMDLVGGDPALDLVNTVTARDTLPRDWLDDYPALLRWARKAALVPAAELQALERLAAAPAAKSAAALARCKQLREALCAALYALAGGGEPAAAELEILDQARLSASRAARLVSRGGRLQTQWSAQRSGLDLIAHVATAHAIELLKDARLERLRVCDGRDCGWVFVDSSKSGRRRWCDMATCGNAAKARRFNQRHKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJV9</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
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            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="GLE_3339"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="73" mass="8036" checksum="7192002F07FDB28C" modified="2016-02-17" version="1">MSERAHRPANATLRFRHSRERGNPGRHPGAAPKSADRAPSRSAAIGLRRLTVRRPPPPFACPARRPDAAFMAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJY1</accession>
    <name>A0A0S2DJY1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF47 family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Pit accessory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_21520</name>
        <name evidence="4" type="ORF">FE772_17235</name>
        <name evidence="2" type="ORF">GLE_3501</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0111 family.</text>
    </comment>
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        <property type="protein sequence ID" value="ALN58846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD61860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948338.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000071.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3501"/>
    <dbReference type="EnsemblBacteria" id="ALN58846">
        <property type="protein sequence ID" value="ALN58846"/>
        <property type="gene ID" value="GLE_3501"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61860">
        <property type="protein sequence ID" value="OPD61860"/>
        <property type="gene ID" value="BV903_21520"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3501"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3446"/>
    <dbReference type="OMA" id="YWLLNEA"/>
    <dbReference type="OrthoDB" id="1837604at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Put_Phosphate_transp_reg"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01865">
        <property type="entry name" value="PhoU_div"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="208" mass="23953" checksum="EEC631DE47F3B6EC" modified="2016-02-17" version="1">MFSLQTIFGQGNQFYTLLEEAAVAAHDATKALHEMLKAADRQPALDAFKLARQRERETSDKISQELVDSFITPIEREDIEALSSALYKIPKQVEKFADRYSLATRHLEHIDFAPRAAMLEQAADVVVKMVHQLRHLKLEPMKALNDQLRALENEADRLMLELYRDIYSGQLDNLQMFLLKEFFEILEKAIDRCREAGVVAYQIVLKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK08</accession>
    <name>A0A0S2DK08_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Oligopeptide transporter, OPT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BV903_24815</name>
        <name evidence="9" type="ORF">FE772_17895</name>
        <name evidence="7" type="ORF">GLE_3637</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000100">
        <property type="protein sequence ID" value="OPD61206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948434.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000100.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3637"/>
    <dbReference type="EnsemblBacteria" id="ALN58981">
        <property type="protein sequence ID" value="ALN58981"/>
        <property type="gene ID" value="GLE_3637"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61206">
        <property type="protein sequence ID" value="OPD61206"/>
        <property type="gene ID" value="BV903_24815"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3637"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3581"/>
    <dbReference type="OMA" id="HIVVSQY"/>
    <dbReference type="OrthoDB" id="809815at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004814">
        <property type="entry name" value="Oligopep_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045035">
        <property type="entry name" value="YSL-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31645">
        <property type="entry name" value="PTHR31645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00733">
        <property type="entry name" value="TIGR00733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="442"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="499"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="530"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="583"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="618"/>
            <end position="637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD61206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW27224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="652" mass="67175" checksum="F92876531CD9E048" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK12</accession>
    <name>A0A0S2DK12_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Penicillin acylase II</fullName>
            <ecNumber evidence="6">3.5.1.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">acyII</name>
        <name evidence="6" type="ORF">GLE_3355</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="5">Binds 1 Ca(2+) ion per dimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S45 family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.11" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948232.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3355"/>
    <dbReference type="EnsemblBacteria" id="ALN58701">
        <property type="protein sequence ID" value="ALN58701"/>
        <property type="gene ID" value="GLE_3355"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3355"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3305"/>
    <dbReference type="OMA" id="EMDVRRH"/>
    <dbReference type="OrthoDB" id="186419at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008953">
        <property type="term" value="F:penicillin amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017000">
        <property type="term" value="P:antibiotic biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.439.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014395">
        <property type="entry name" value="Pen/GL7ACA/AHL_acylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043147">
        <property type="entry name" value="Penicillin_amidase_A-knob"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023343">
        <property type="entry name" value="Penicillin_amidase_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043146">
        <property type="entry name" value="Penicillin_amidase_N_B-knob"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002692">
        <property type="entry name" value="S45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34218">
        <property type="entry name" value="PTHR34218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01804">
        <property type="entry name" value="Penicil_amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001227">
        <property type="entry name" value="Pen_acylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0865">Zymogen</keyword>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="336"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001227-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001227-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="805" mass="86595" checksum="1F33231C57D140D0" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK15</accession>
    <name>A0A0S2DK15_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">N5-carboxyaminoimidazole ribonucleotide synthase</fullName>
            <shortName evidence="3 5">N5-CAIR synthase</shortName>
            <ecNumber evidence="3 5">6.3.4.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3 5">5-(carboxyamino)imidazole ribonucleotide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5 7" type="primary">purK</name>
        <name evidence="8" type="ORF">FE772_17695</name>
        <name evidence="7" type="ORF">GLE_3591</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).</text>
    </comment>
    <comment type="function">
        <text evidence="5">Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 5">
            <text>5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ATP + hydrogencarbonate = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19317"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58730"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 5">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the PurK/PurT family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.18" evidence="3 5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948402.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3591"/>
    <dbReference type="EnsemblBacteria" id="ALN58935">
        <property type="protein sequence ID" value="ALN58935"/>
        <property type="gene ID" value="GLE_3591"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3591"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3535"/>
    <dbReference type="OMA" id="ITFDHEH"/>
    <dbReference type="OrthoDB" id="1165275at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00942"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034028">
        <property type="term" value="F:5-(carboxyamino)imidazole ribonucleotide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004638">
        <property type="term" value="F:phosphoribosylaminoimidazole carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01928">
        <property type="entry name" value="PurK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003135">
        <property type="entry name" value="ATP-grasp_carboxylate-amine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005875">
        <property type="entry name" value="PurK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040686">
        <property type="entry name" value="PurK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02222">
        <property type="entry name" value="ATP-grasp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17769">
        <property type="entry name" value="PurK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01161">
        <property type="entry name" value="purK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 3 5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="6">
        <location>
            <begin position="103"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="144"/>
            <end position="150"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="178"/>
            <end position="181"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="262"/>
            <end position="263"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW27191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="379" mass="40204" checksum="0D7D5412AFDF98FF" modified="2016-02-17" version="1">MTTVGILGGGQLARMLALSGAPLGLRFLVLDNTADACAGQFAPMVVGDYTDQAALDEFASKIDVATFDFENVPAESARWLAERRPVFPSPRALAVAQDRLAEKTLFRELDIPVPDFAAIDSRAGLDAALAAIGTPCILKTRRLGYDGKGQFRIKTAADADAAWAALGAQADTVGLILEGFVRFERELSVVAVRGRDGEFRAWPLTENWHVDGVLSASLAPAVADEALAATAVAHARKLADALDYVGVFALELFCRGGVLLANELAPRVHNSGHWTIEGAETSQFQNHLRAVLGLPLGDTRMLGHACMLNWIGAMPDAAPVLAEAGGHWHDYGKSPREGRKVGHATVRADSAHALAQALARVGVALGRQEQVAPVIARLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK80</accession>
    <name>A0A0S2DK80_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 15">Cytochrome b</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">BV903_16920</name>
        <name evidence="21" type="ORF">FE772_17735</name>
        <name evidence="19" type="ORF">GLE_3600</name>
    </gene>
    <organism evidence="19 22">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="19 22" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 22">C3</strain>
        </source>
    </reference>
    <reference evidence="20 23" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 23">B25</strain>
        </source>
    </reference>
    <reference evidence="21 24" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 24">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 15">Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="15">Binds 2 heme groups non-covalently.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="14">Binds 2 heme groups non-covalently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the cytochrome b family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000045">
        <property type="protein sequence ID" value="OPD62774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948408.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3600"/>
    <dbReference type="EnsemblBacteria" id="ALN58944">
        <property type="protein sequence ID" value="ALN58944"/>
        <property type="gene ID" value="GLE_3600"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62774">
        <property type="protein sequence ID" value="OPD62774"/>
        <property type="gene ID" value="BV903_16920"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3600"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3544"/>
    <dbReference type="OMA" id="RFFAFHF"/>
    <dbReference type="OrthoDB" id="262439at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045275">
        <property type="term" value="C:respiratory chain complex III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008121">
        <property type="term" value="F:ubiquinol-cytochrome-c reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00284">
        <property type="entry name" value="Cytochrome_b_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005798">
        <property type="entry name" value="Cyt_b/b6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036150">
        <property type="entry name" value="Cyt_b/b6_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005797">
        <property type="entry name" value="Cyt_b/b6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027387">
        <property type="entry name" value="Cytb/b6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030689">
        <property type="entry name" value="Cytochrome_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00032">
        <property type="entry name" value="Cytochrom_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00033">
        <property type="entry name" value="Cytochrome_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038885">
        <property type="entry name" value="COB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="SSF81342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81648">
        <property type="entry name" value="SSF81648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51003">
        <property type="entry name" value="CYTB_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51002">
        <property type="entry name" value="CYTB_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 14 15" id="KW-0349">Heme</keyword>
    <keyword evidence="11 14" id="KW-0408">Iron</keyword>
    <keyword evidence="12 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="7 15 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="258"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="352"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="CYTB_NTER" evidence="17">
        <location>
            <begin position="12"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="CYTB_CTER" evidence="18">
        <location>
            <begin position="239"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <label>b562</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <label>b566</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <label>b562</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <label>b566</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>a ubiquinone</name>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR038885-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR038885-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ALN58944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="OPD62774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="QCW27196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="419" mass="47837" checksum="F9F50C982CE7A3EC" modified="2016-02-17" version="1">MANILTRTANNVFGWVTDRAPGMMPMYRKHMSEYYAPKNFNIWYYFGSLALLVLVNQIVTGIFLTMHFKPSAAEAFSSVEYIMRDVEWGWLIRYMHSTGASLFFIVVYLHMFRGLLYGSYQKPRELVWILGMLIYLVLMAEAFMGYVLPWGQMSFWGAKVIISLFGAIPVIGNGLTEWIMGDYLPGDATLNRFFALHVIALPLVLLLLVVLHLGALHEVGSNNPEGVDTKHGPKGNRWDANKPIDTIPFHPYYTVKDLFGVGFFLMLAAFIIFFAPAMGGWFLEHDNFTEANRLVTPEHIKPVWYYTPYYAMLRVIPDKLGGVIVMFLAIAILFLVPWLDRCKVKSVRYRGLISKFMLMLLAVCFVWLGKIGAGPGTDPVETVIGRVLTFLYFAFFITMPVWTKLDKTKPVPERVTMHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK96</accession>
    <name>A0A0S2DK96_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3616</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58960">
        <property type="protein sequence ID" value="ALN58960"/>
        <property type="gene ID" value="GLE_3616"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3616"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3560"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="61" mass="6031" checksum="4D3F86622DE84EF7" modified="2016-02-17" version="1">MAGSFGRRQGAAPACGQDRGPAGRGQGADRRGGSAGRGSATACAVLRLSRGADKAFRAGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKF7</accession>
    <name>A0A0S2DKF7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 4" type="primary">rpsQ</name>
        <name evidence="5" type="ORF">BV903_22990</name>
        <name evidence="7" type="ORF">D9T17_09475</name>
        <name evidence="6" type="ORF">FE772_18605</name>
        <name evidence="4" type="ORF">GLE_3781</name>
    </gene>
    <organism evidence="4 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 8">C3</strain>
        </source>
    </reference>
    <reference evidence="5 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">OH11</strain>
        </source>
    </reference>
    <reference evidence="6 11" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000077">
        <property type="protein sequence ID" value="OPD61608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000023">
        <property type="protein sequence ID" value="ROU07190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948547.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3781"/>
    <dbReference type="EnsemblBacteria" id="ALN59125">
        <property type="protein sequence ID" value="ALN59125"/>
        <property type="gene ID" value="GLE_3781"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61608">
        <property type="protein sequence ID" value="OPD61608"/>
        <property type="gene ID" value="BV903_22990"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3781"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3725"/>
    <dbReference type="OMA" id="HPMYGKF"/>
    <dbReference type="OrthoDB" id="2035880at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01345_B">
        <property type="entry name" value="Ribosomal_S17_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019984">
        <property type="entry name" value="Ribosomal_S17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_S17/S11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="PTHR10744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00973">
        <property type="entry name" value="RIBOSOMALS17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03635">
        <property type="entry name" value="uS17_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD61608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW27352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROU07190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="89" mass="10077" checksum="2B04F430C69D4AD7" modified="2016-02-17" version="1">MTDNKTEKAVRTVEGRVVSNKMDKTVTVLVERQVKHALYGKYIRRSTKLHAHDADNACKEGDIVRVKEIAPLSKTKNWSVVEIVSRVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKM1</accession>
    <name>A0A0S2DKM1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aspartate kinase</fullName>
            <ecNumber evidence="4">2.7.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">lysA</name>
        <name evidence="14" type="ORF">FE772_18380</name>
        <name evidence="13" type="ORF">GLE_3732</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">C3</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-aspartate = 4-phospho-L-aspartate + ADP</text>
            <dbReference type="Rhea" id="RHEA:23776"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="11">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="11">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the Orn/Lys/Arg decarboxylase class-II family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.4" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948507.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3732"/>
    <dbReference type="EnsemblBacteria" id="ALN59076">
        <property type="protein sequence ID" value="ALN59076"/>
        <property type="gene ID" value="GLE_3732"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3732"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3677"/>
    <dbReference type="OMA" id="VEALRNW"/>
    <dbReference type="OrthoDB" id="1067792at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00015"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00461"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00462"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004072">
        <property type="term" value="F:aspartate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008836">
        <property type="term" value="F:diaminopimelate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001341">
        <property type="entry name" value="Asp_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042199">
        <property type="entry name" value="AsparK_Bifunc_asparK/hSer_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018042">
        <property type="entry name" value="Aspartate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011246">
        <property type="entry name" value="DAP_dec_asp_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002986">
        <property type="entry name" value="DAP_deCOOHase_LysA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022643">
        <property type="entry name" value="De-COase2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022657">
        <property type="entry name" value="De-COase2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022653">
        <property type="entry name" value="De-COase2_pyr-phos_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00278">
        <property type="entry name" value="Orn_DAP_Arg_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036459">
        <property type="entry name" value="DAP_dec_asp_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01181">
        <property type="entry name" value="DAPDCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00657">
        <property type="entry name" value="asp_kinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00324">
        <property type="entry name" value="ASPARTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00878">
        <property type="entry name" value="ODR_DC_2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00879">
        <property type="entry name" value="ODR_DC_2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="7 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="13" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="12">
        <location>
            <begin position="328"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN59076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW27313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="866" mass="93836" checksum="E3CF62BA4A879380" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKN9</accession>
    <name>A0A0S2DKN9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">50S ribosomal protein L18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 8" type="primary">rplR</name>
        <name evidence="9" type="ORF">BV903_22955</name>
        <name evidence="11" type="ORF">D9T17_09510</name>
        <name evidence="10" type="ORF">FE772_18570</name>
        <name evidence="8" type="ORF">GLE_3774</name>
    </gene>
    <organism evidence="8 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 12">C3</strain>
        </source>
    </reference>
    <reference evidence="9 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">OH11</strain>
        </source>
    </reference>
    <reference evidence="10 15" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uL18 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000077">
        <property type="protein sequence ID" value="OPD61601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000023">
        <property type="protein sequence ID" value="ROU07197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948541.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3774"/>
    <dbReference type="EnsemblBacteria" id="ALN59118">
        <property type="protein sequence ID" value="ALN59118"/>
        <property type="gene ID" value="GLE_3774"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61601">
        <property type="protein sequence ID" value="OPD61601"/>
        <property type="gene ID" value="BV903_22955"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3774"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3718"/>
    <dbReference type="OMA" id="NKQIYAQ"/>
    <dbReference type="OrthoDB" id="1963491at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01337_B">
        <property type="entry name" value="Ribosomal_L18_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005484">
        <property type="entry name" value="Ribosomal_L18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004389">
        <property type="entry name" value="Ribosomal_L18_bac-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12899">
        <property type="entry name" value="PTHR12899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00861">
        <property type="entry name" value="Ribosomal_L18p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00060">
        <property type="entry name" value="L18_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD61601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROU07197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="117" mass="12652" checksum="E411E02C0147DFA2" modified="2016-02-17" version="1">MNKNTARLRRAKSTRSHIRNLGVARLTVLRTGQHLYAQIFTADGSKVLATASTVQADVKEGLKNGKNADAAVKVGKMIAERAKAAGIEKVAFDRSGYRYHGRIKALADAAREGGLQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKT7</accession>
    <name>A0A0S2DKT7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">M20/M25/M40 family metallo-hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Peptidase, M28 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_18885</name>
        <name evidence="2" type="ORF">GLE_3835</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948589.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3835"/>
    <dbReference type="EnsemblBacteria" id="ALN59178">
        <property type="protein sequence ID" value="ALN59178"/>
        <property type="gene ID" value="GLE_3835"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3835"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3777"/>
    <dbReference type="OMA" id="QNFMDIT"/>
    <dbReference type="OrthoDB" id="1465483at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="PTHR12147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M28" evidence="1">
        <location>
            <begin position="229"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="444" mass="46863" checksum="1B080F7C9EE7BC27" modified="2016-02-17" version="1">MRAIGRFRRGVRRARPVPRREAPFLEIAVSRFAPQLLLSLAASVAAPAIASGPAAAGDDPLKPVYVVAAERTHRAALADAGTRLRTLAGRDGEALAISRVPAGRLPELVRHVHEKEKRCGGFFAFDSREQAEAFVRDDLSALAVSAQAVEYTVDNQATVTPWLGQVREADIRATIRSLSGNWTTRHAATASGRAASDWIRDSWKRLAANRADVSVEQVACGNCGQQPSVVLTVRGNELPDEVAVLGAHMDSIASGGSSASAPGADDDASGVATLTEVLRVALGSGWKPRRTVKFMAYAAEEIGLRGSNAIAVDHRNRGVNVVGVLQLDMTNYRTAGAADLRLISDNSNAGLQGLVRQLYSRYLGGGTLAEYRCGYGCSDHASWTSAGYPAAMLFEGGTATGGYSPHIHTRNDTLANMGNSAANSVPFAKLGLAFLGELGKTSGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL17</accession>
    <name>A0A0S2DL17_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3916"/>
    <dbReference type="EnsemblBacteria" id="ALN59258">
        <property type="protein sequence ID" value="ALN59258"/>
        <property type="gene ID" value="GLE_3916"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3916"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3853"/>
    <dbReference type="OMA" id="PGNLPHI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009706">
        <property type="entry name" value="DUF1287"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06940">
        <property type="entry name" value="DUF1287"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011444">
        <property type="entry name" value="DUF1287"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="11"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="213" mass="23336" checksum="582483F5060A3185" modified="2016-02-17" version="1">MLIAALAAGCSQPASPPAERSAADATPPAAAEPAKPSPPLVAAARAQVGVVRLYDPAYVRLGYPGGDVAPDRGVCTDVVIRALRVQGLDLQQRVHEDMRANFAAYPSLWRASATDRSIDHRRVPNLRRWFERQGWSLPVSADAADYRAGDVVTWDLSRGQTHIGIVSDRRSWDRRRPLILHNIARGTQEEDVLFAYAVTGRYRPQLPPAVASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL24</accession>
    <name>A0A0S2DL24_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyl transferase</fullName>
            <ecNumber evidence="4">2.4.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_3876</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3876"/>
    <dbReference type="EnsemblBacteria" id="ALN59219">
        <property type="protein sequence ID" value="ALN59219"/>
        <property type="gene ID" value="GLE_3876"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3876"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3815"/>
    <dbReference type="OMA" id="CTALMER"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13579">
        <property type="entry name" value="Glyco_trans_4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="3">
        <location>
            <begin position="30"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="237"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="429"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="943" mass="101782" checksum="C936BB4240743F49" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLE1</accession>
    <name>A0A0S2DLE1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3989</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59331">
        <property type="protein sequence ID" value="ALN59331"/>
        <property type="gene ID" value="GLE_3989"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3989"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3926"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="57" mass="5830" checksum="3D76A55137AEFDC4" modified="2016-02-17" version="1">MEPARIGLSHPDVRSVSATYAANPGLGAAAGTARGRSRAVDRTAAAAQAARRRRLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLL0</accession>
    <name>A0A0S2DLL0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLE_4238</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4238"/>
    <dbReference type="EnsemblBacteria" id="ALN59579">
        <property type="protein sequence ID" value="ALN59579"/>
        <property type="gene ID" value="GLE_4238"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4238"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4179"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="131"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="301"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="338"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="367"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="406"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="10">
        <location>
            <begin position="54"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="536"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN59579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="563" mass="61627" checksum="5514719951632486" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLN4</accession>
    <name>A0A0S2DLN4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA polymerase I</fullName>
            <ecNumber evidence="3">2.7.7.7</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Exodeoxyribonuclease IX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">polA</name>
        <name evidence="4" type="ORF">BV903_16100</name>
        <name evidence="3" type="ORF">GLE_3872</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">B25</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.7" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000042">
        <property type="protein sequence ID" value="OPD62913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948611.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000042.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3872"/>
    <dbReference type="EnsemblBacteria" id="ALN59215">
        <property type="protein sequence ID" value="ALN59215"/>
        <property type="gene ID" value="GLE_3872"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62913">
        <property type="protein sequence ID" value="OPD62913"/>
        <property type="gene ID" value="BV903_16100"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3872"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3811"/>
    <dbReference type="OMA" id="WRVDLIP"/>
    <dbReference type="OrthoDB" id="1220182at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033567">
        <property type="term" value="P:DNA replication, Okazaki fragment processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09898">
        <property type="entry name" value="H3TH_53EXO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020046">
        <property type="entry name" value="5-3_exonucl_a-hlix_arch_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002421">
        <property type="entry name" value="5-3_exonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020045">
        <property type="entry name" value="DNA_polI_H3TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038969">
        <property type="entry name" value="FEN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42646">
        <property type="entry name" value="PTHR42646"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01367">
        <property type="entry name" value="5_3_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02739">
        <property type="entry name" value="5_3_exonuc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00475">
        <property type="entry name" value="53EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="SSF47807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="53EXOc" evidence="2">
        <location>
            <begin position="11"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD62913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="313" mass="33845" checksum="1833F758923D7D8E" modified="2016-02-17" version="1">MTSPPAPAAQTPVYLVDASLYVFRAWHSIPDDFQDAEGWPSNAVHGFARFLLELIERERPQHIAVAFDEALDSCFRNALYPAYKANREPAPDALKRQFGHCKALCSALGLSVLADAQYEADDLIGSALLRMRGHGYRGVIVSADKDLSQLLDAADEQWDFARGLRWTAAGVPERHGVQATQIADYLALCGDAVDNIPGVPGIGAKTAAALLGHFGSLDALLARVEEVPFLRLRGAASAAAKLRAHRDQALLCRQLTTIALDAPLPDDGGRYRRGGADADTLQALCDRLRFGPMTRRRLYAAVGLDFAASQVPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLP8</accession>
    <name>A0A0S2DLP8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4166 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948783.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4101"/>
    <dbReference type="EnsemblBacteria" id="ALN59443">
        <property type="protein sequence ID" value="ALN59443"/>
        <property type="gene ID" value="GLE_4101"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4101"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4043"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025311">
        <property type="entry name" value="DUF4166"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13761">
        <property type="entry name" value="DUF4166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4166" evidence="1">
        <location>
            <begin position="29"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="238" mass="26066" checksum="C90DFD35CD2E15DD" modified="2016-02-17" version="1">MTNPSRDASRLGAREGLYPRVLGVRFVLLPRTLRLMHGRSGRQTYRGEAKVERGSGLWSRLFARIVRLPAAYAGPIEVEVVAGPRGETWTRRFGKSRMRSRLAGRDGLVLERLGPMRFAFALEPVGEAPEAALARTVSAHTGDSITVSSAALPAAAMGAPTSYGIAGQADEDGIGNEPGLVWRLMRVRAFGLPLPAGWFARVQAREFEREGRYHFEVDAQLPGVGLLVRYRGWLDVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLS9</accession>
    <name>A0A0S2DLS9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">UDP-N-acetylmuramate--L-alanine ligase</fullName>
            <ecNumber evidence="4 11">6.3.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">UDP-N-acetylmuramoyl-L-alanine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 15" type="primary">murC</name>
        <name evidence="15" type="ORF">GLE_4130</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + L-alanine + UDP-N-acetyl-alpha-D-muramate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine</text>
            <dbReference type="Rhea" id="RHEA:23372"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:70757"/>
            <dbReference type="ChEBI" id="CHEBI:83898"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the MurCDEF family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.8" evidence="4 11"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4130"/>
    <dbReference type="EnsemblBacteria" id="ALN59472">
        <property type="protein sequence ID" value="ALN59472"/>
        <property type="gene ID" value="GLE_4130"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4130"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4072"/>
    <dbReference type="OMA" id="DITYQLR"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008763">
        <property type="term" value="F:UDP-N-acetylmuramate-L-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00046">
        <property type="entry name" value="MurC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005758">
        <property type="entry name" value="UDP-N-AcMur_Ala_ligase_MurC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01082">
        <property type="entry name" value="murC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="7 11" id="KW-0133">Cell shape</keyword>
    <keyword evidence="10 11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 11" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="12">
        <location>
            <begin position="22"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="14">
        <location>
            <begin position="124"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="13">
        <location>
            <begin position="326"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="126"/>
            <end position="132"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ALN59472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="481" mass="50589" checksum="58A720DD3E23B897" modified="2016-02-17" version="1">MSTALRRRLQHTGDLAKAFPRVHFVGIGGTGMSGIAEVMCTLGYQVSGSDMADNAVTRRLASMGATVHRGHAAANVLGADCVVVSSAIKRDNPELMEARAQRIPVVPRAEMLAELMRFRRGIAVAGTHGKTTTTSLTASVLAEGGIDPTFVIGGKLLAAGANAGLGGGQWLVAEADESDGSFLRLNPQIAIVTNIDADHLENYGGDFAKVQAAFEEFLHRLPFYGLAVLCIDDANVARLAAETPRHVMTYGFAPEADVRAEDVSQDGGAMRFALCLPDATRTAVTLALPGRHNVLNALAAAAVAWQLGVQPEAIARALEKFAGIGRRFNLLAQIKTDKGATVQLVDDYGHHPKELEAVFAAARGGWPDKRLVVAFQPHRYSRTRDLFDDFAAVLSSVDALVLTEVYPAGEAPIAGADAKSLARAIRARGRIDPVVVSGAADLSSVLPDVLNDGDLLLLMGAGDIGAAAQQLATTGFQGESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLV2</accession>
    <name>A0A0S2DLV2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DMT family transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Integral membrane protein DUF6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_21030</name>
        <name evidence="3" type="ORF">GLE_4297</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948943.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59638">
        <property type="protein sequence ID" value="ALN59638"/>
        <property type="gene ID" value="GLE_4297"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4297"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4236"/>
    <dbReference type="OMA" id="TWGINNA"/>
    <dbReference type="OrthoDB" id="1515911at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="6"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="143"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="292" mass="31149" checksum="8D048B27D31FDFDC" modified="2016-02-17" version="1">MPARDLLLLLLVVLSWAINFLTSALALREIPPFLFTALRFALLALPLAFFLKRPAPGQWPRLIAVCLCIGVLHFGLSFSALKAAGDLSSPAIVMQSYVPMTALLAWWLLGERFAWRTGAAIAISFCGVLVLGFDPMVLDHPLAVVLMLVSAAFLALGTVLMKGLRGLDMLSQQGWTALIAVTPLLAISLALEPGGVAALPHVGWVAWVGVAYAAFVSSLLGHGLYYVLVQRHPVAQITPWLLLAPVIAIGLGIAFWGDRPGPSLWVGGAMVLGGVLLIALRNLAKSRALRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM62</accession>
    <name>A0A0S2DM62_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Protein ApaG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 6" type="primary">apaG</name>
        <name evidence="5" type="ORF">BV903_19105</name>
        <name evidence="7" type="ORF">D9T17_08870</name>
        <name evidence="6" type="ORF">FE772_19220</name>
        <name evidence="4" type="ORF">GLE_3914</name>
    </gene>
    <organism evidence="4 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 8">C3</strain>
        </source>
    </reference>
    <reference evidence="5 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">OH11</strain>
        </source>
    </reference>
    <reference evidence="6 11" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 11">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="NZ_RCTY01000022.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3914"/>
    <dbReference type="EnsemblBacteria" id="ALN59256">
        <property type="protein sequence ID" value="ALN59256"/>
        <property type="gene ID" value="GLE_3914"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62334">
        <property type="protein sequence ID" value="OPD62334"/>
        <property type="gene ID" value="BV903_19105"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3914"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3851"/>
    <dbReference type="OMA" id="YVSGCNL"/>
    <dbReference type="OrthoDB" id="1835593at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00791">
        <property type="entry name" value="ApaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007474">
        <property type="entry name" value="ApaG_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036767">
        <property type="entry name" value="ApaG_sf"/>
    </dbReference>
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        <property type="entry name" value="Uncharacterised_ApaG"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF110069"/>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="3"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00017693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD62334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW27451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROU07410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="127" mass="14223" checksum="B06BAB63F6843CB1" modified="2016-02-17" version="1">MNRPTEYVFDIDVATRYLDDQSAPEQDRYVFAYTIHIRNAGTVPARLISRHWVITDANGKVQEVRGDGVVGEQPWLRPGDDFEYTSGAVLETSLGTMEGTYAMVADDGTRFDAPVPTFTLTIPRTLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMA5</accession>
    <name>A0A0S2DMA5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA-binding protein H-NS</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">H-NS histone family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hns</name>
        <name evidence="9" type="ORF">D9T17_07745</name>
        <name evidence="8" type="ORF">FE772_20610</name>
        <name evidence="7" type="ORF">GLE_4204</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">OH11</strain>
        </source>
    </reference>
    <reference evidence="8 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histone-like protein H-NS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000020">
        <property type="protein sequence ID" value="ROU07666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948867.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000020.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4204"/>
    <dbReference type="EnsemblBacteria" id="ALN59545">
        <property type="protein sequence ID" value="ALN59545"/>
        <property type="gene ID" value="GLE_4204"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4204"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4146"/>
    <dbReference type="OMA" id="NPKETWT"/>
    <dbReference type="OrthoDB" id="1911889at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009295">
        <property type="term" value="C:nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027444">
        <property type="entry name" value="H-NS_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037150">
        <property type="entry name" value="H-NS_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001801">
        <property type="entry name" value="Histone_HNS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00816">
        <property type="entry name" value="Histone_HNS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00528">
        <property type="entry name" value="HNS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNS" evidence="6">
        <location>
            <begin position="79"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="62"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW27680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROU07666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="128" mass="13792" checksum="70EDDDEE748C1BAE" modified="2016-02-17" version="1">MTIDISALSAKELENLISQAKKRKTTLNKRKPLAAVRKKVVALLKAEGYALEELFGGAAPAARAGRPAKAAKSAAPAARKARKPLGKVAPKYRNPANTGETWTGRGKQPRWLAAYTAQGKKLEDFLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMD2</accession>
    <name>A0A0S2DMD2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sensory box-containing diguanylate cyclase/cyclic diguanylate phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4325"/>
    <dbReference type="EnsemblBacteria" id="ALN59666">
        <property type="protein sequence ID" value="ALN59666"/>
        <property type="gene ID" value="GLE_4325"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4325"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4264"/>
    <dbReference type="OMA" id="SDICARA"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="1">
        <location>
            <begin position="236"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="364" mass="39541" checksum="B43AA2BAB1190A9C" modified="2016-02-17" version="1">MVPDPPPPTPADEAARLLALDAYGLLDSVAESAYDDIVRLAATLCDTPGAALALLDRERVWFKARVGVAPSELPRSHSICAELIWQSQSGRLLTIDDVGGDPRFAPLGLSLEDGRALRFYAGAPLWTPDGHPLGTVCVLDAVPRRLRPAQAEGLAALGRQTQHLFELRRYALEQRRLLSEREAFALQMESAQADLLRRNEQLQHSASHDALTGLLNRSALAQLQGSPDTVHRLGRAAYTLMLIDVDHFKQVNDRHGHLLGDRALRAVADAVAASIRDDDVAIRYGGEEFLVVLPGTRLADAAEVGERIRRRVARSSLPFALTVSIGMAAGEPGRDGPEQVFDRADQALYRAKAGGRDRLVADEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMJ0</accession>
    <name>A0A0S2DMJ0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4367</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59708">
        <property type="protein sequence ID" value="ALN59708"/>
        <property type="gene ID" value="GLE_4367"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4367"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4306"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="69" mass="7456" checksum="8005094A3F1B3104" modified="2016-02-17" version="1">MCRRRIGMSAAHGSRTHAGAHDSAAFVNVLFRSGGACGRRSGLAISRSRFHARSRRGLAQPPPRLVKET</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMJ1</accession>
    <name>A0A0S2DMJ1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF465 domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">UptF protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_04475</name>
        <name evidence="4" type="ORF">D9T17_07565</name>
        <name evidence="3" type="ORF">FE772_20820</name>
        <name evidence="1" type="ORF">GLE_4252</name>
    </gene>
    <organism evidence="1 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 5">C3</strain>
        </source>
    </reference>
    <reference evidence="2 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">OH11</strain>
        </source>
    </reference>
    <reference evidence="3 8" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000008">
        <property type="protein sequence ID" value="OPD65180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000020">
        <property type="protein sequence ID" value="ROU07632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948905.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000020.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4252"/>
    <dbReference type="EnsemblBacteria" id="ALN59593">
        <property type="protein sequence ID" value="ALN59593"/>
        <property type="gene ID" value="GLE_4252"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65180">
        <property type="protein sequence ID" value="OPD65180"/>
        <property type="gene ID" value="BV903_04475"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4252"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4192"/>
    <dbReference type="OMA" id="QHRKLNK"/>
    <dbReference type="OrthoDB" id="2093541at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007420">
        <property type="entry name" value="DUF465"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038444">
        <property type="entry name" value="DUF465_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04325">
        <property type="entry name" value="DUF465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD65180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROU07632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="72" mass="8545" checksum="9A00BF0983CED55D" modified="2016-02-17" version="1">MFEERPQPEIDALIKSNPEFKQLYQRHKDLDKKVMDAELGVLPIDDTTLGQMKREKLAAKDRLLLLYEQQHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMY5</accession>
    <name>A0A0S2DMY5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA polymerase sigma factor, sigma-70 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_4649</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4649"/>
    <dbReference type="EnsemblBacteria" id="ALN59990">
        <property type="protein sequence ID" value="ALN59990"/>
        <property type="gene ID" value="GLE_4649"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4649"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4585"/>
    <dbReference type="OMA" id="RANMPLV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="37"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4" evidence="6">
        <location>
            <begin position="193"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="253" mass="27893" checksum="41BAF2B8C5E4163D" modified="2016-02-17" version="1">MTAPPALAAEDDAAPAAEAALWAALRRDGSTAAREALFLRYQPYAQALAARIYGGRHSREVEFRDYQQLAYIGLLDSMDRYDPQQGAGFKTFCTPRITGNVLDGLRQLSEAQEQISLKRRLQRDRLSSLKDGGRDGKPAGRKLDALSELAVGLAIGHMLEGTGMYADGEQADRHDGYAAVAWQQTCRSLRQAVERLPADMGKVVSYHYFHSLPFEQIAGILGLSKGRISQIHRAALTQLREKIQPHSPSRTTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN20</accession>
    <name>A0A0S2DN20_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Citrate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FE772_23270</name>
        <name evidence="8" type="ORF">GLE_4782</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949312.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4782"/>
    <dbReference type="EnsemblBacteria" id="ALN60123">
        <property type="protein sequence ID" value="ALN60123"/>
        <property type="gene ID" value="GLE_4782"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4782"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4716"/>
    <dbReference type="OMA" id="FMSNDGF"/>
    <dbReference type="OrthoDB" id="497060at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015137">
        <property type="term" value="F:citrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014738">
        <property type="entry name" value="Citrate_transporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00784">
        <property type="entry name" value="citMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="333"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="389"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="420"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="CitMHS" evidence="7">
        <location>
            <begin position="13"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN60123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW28135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="442" mass="47305" checksum="33BF4DC50E1226BD" modified="2016-02-17" version="1">MLTILGFGMVLTFMYLIMSKRLSPLVALIVIPIAFALAGGFGAGIGEMMIEGIKKIAPTGVMLMFAILYFGVMIDAGLFDPIVKRILKLVKGDPVKIVVGTAVLAMLISLDGDGSTTYMITVSAMLPLFQRLRMNALNLTCVTILASGVMNLTPWGGPTARAATALHVDPSEVFVPLIPAMVVSLLSILVLAWYLGLRERKRLGIVTLDGHAADWNPELDTASDNLPTLADSEDTKRPKLLWVNAGLTTALMAALILGLLPLPVLFMIGFAIALVINYPDLAEQRRRIGNHAGNVLAVVSLIFAAGIFTGILSNTGMVEAMSRSFLAVIPDAWGPYLAVITAIASMPFTFFMSNDAFYFGVLPILSEAAGHYGITPVEMARASLAGQPVHLLSPLVPSTYLLVGMANVDFADHQKFTLKWAVMVSLVLMFASLGFALYPFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN44</accession>
    <name>A0A0S2DN44_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4502</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4502"/>
    <dbReference type="EnsemblBacteria" id="ALN59843">
        <property type="protein sequence ID" value="ALN59843"/>
        <property type="gene ID" value="GLE_4502"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4502"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4438"/>
    <dbReference type="OMA" id="LQHDIFT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="220" mass="24273" checksum="B678B2696FEA3804" modified="2016-02-17" version="1">MSFPAPYAASDGIKAYTQPGLRLYDPLIVGLLARHVWKCPAEAFIAAYRRHLRANHADVGVGTGYCLDRCGFDVPAPRLALIDLQPNCLGFTARRLSRYRPETYLRDARQPLLGIPAFDSVALGGLLHCLPGDMHEKAAVFDALRPICNPGATVFGFTLVNDAIAATRSRRLAWRALNDLRVVNCRDDTADGLRHELATRFDDCTVETIGCFAFFSARVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNH2</accession>
    <name>A0A0S2DNH2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rhs family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4692</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4692"/>
    <dbReference type="EnsemblBacteria" id="ALN60033">
        <property type="protein sequence ID" value="ALN60033"/>
        <property type="gene ID" value="GLE_4692"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4692"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4627"/>
    <dbReference type="OMA" id="RITRMEY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045351">
        <property type="entry name" value="DUF6531"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031325">
        <property type="entry name" value="RHS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006530">
        <property type="entry name" value="YD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20148">
        <property type="entry name" value="DUF6531"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05593">
        <property type="entry name" value="RHS_repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01643">
        <property type="entry name" value="YD_repeat_2x"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6531" evidence="2">
        <location>
            <begin position="43"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1317"/>
            <end position="1336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1383" mass="151967" checksum="298128879B7EB8B3" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNM1</accession>
    <name>A0A0S2DNM1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_22845</name>
        <name evidence="2" type="ORF">GLE_4694</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949242.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4694"/>
    <dbReference type="EnsemblBacteria" id="ALN60035">
        <property type="protein sequence ID" value="ALN60035"/>
        <property type="gene ID" value="GLE_4694"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4694"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4628"/>
    <dbReference type="OMA" id="WAPVHYQ"/>
    <dbReference type="OrthoDB" id="486752at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242696" evidence="1">
        <location>
            <begin position="31"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="335" mass="35765" checksum="4277EF265211A1B6" modified="2016-02-17" version="1">MLRPASSTLRRAVRAAVAGLGLLAAFGANAAALSAANAADRAALALRWAPVHYQDVDQTGSHALGGAADYIARYDFDGDLDARNNWDRAGQPAYPLAAHAYYSVVETATHWYITYLFFHPRDWTDSFFDTEHENDAEGVMFAIARDGSAYGTLKAAVTVAHTDFFSYVPAGSDWTGNAENVDGSLSFLSYLGAPHPVTAQEAKGHGLKAWPAYDIKGDGVVYYPSLTVAEVPSSPDDRDVKYKLIDIFEPGGMWDQRNNPSLFAGYGSFAGDKSGGCGSGAIGCSVNAANAPWGWDDSNDGPGRGALATDPVGLTMNYFRIPEAVSGAYSYNPYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNQ5</accession>
    <name>A0A0S2DNQ5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_15795</name>
        <name evidence="4" type="ORF">FE772_22755</name>
        <name evidence="2" type="ORF">GLE_4672</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000041">
        <property type="protein sequence ID" value="OPD62936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949228.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60013">
        <property type="protein sequence ID" value="ALN60013"/>
        <property type="gene ID" value="GLE_4672"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62936">
        <property type="protein sequence ID" value="OPD62936"/>
        <property type="gene ID" value="BV903_15795"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4672"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4608"/>
    <dbReference type="OMA" id="CIAYAIH"/>
    <dbReference type="OrthoDB" id="1934936at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="107" mass="11615" checksum="18C0C680B6365619" modified="2016-02-17" version="1">MPDILVPITLFVCIAFAIKVVVEARVRGKLAQSAGSEELLRSLARDEDQRRRHGALRWGIVLVLLAIAFAIIEAAGWRDATAGTFALLLGAVGLGNLAYYVIVRKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPA1</accession>
    <name>A0A0S2DPA1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FE772_24590</name>
        <name evidence="8" type="ORF">GLE_5073</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4 5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949533.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5073"/>
    <dbReference type="EnsemblBacteria" id="ALN60414">
        <property type="protein sequence ID" value="ALN60414"/>
        <property type="gene ID" value="GLE_5073"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5073"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5000"/>
    <dbReference type="OMA" id="MGANPHK"/>
    <dbReference type="OrthoDB" id="1861282at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000774">
        <property type="entry name" value="PPIase_FKBP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036944">
        <property type="entry name" value="PPIase_FKBP_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01346">
        <property type="entry name" value="FKBP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0697">Rotamase</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033243145" description="Peptidyl-prolyl cis-trans isomerase" evidence="6">
        <location>
            <begin position="24"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="7">
        <location>
            <begin position="161"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN60414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW28353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="256" mass="27329" checksum="DE4BD696CEDC2C1F" modified="2016-02-17" version="1">MPRSLLVLSALSLALAAALVACAPSGRPKPGAAAAPAPLAAADVASEKARISYVVGRDFARSVEPIRAELDAELVLRAIRDAQAGRPSLFDESETKRIRDGFSAHLRDKHDQQVKALAARNLAAGEAFLSKNANADGVKTTASGLQYQMLREGKGAHPKASDTVRVNYVGTLIDGRKFESTYDTDHPAEFVLAQVMPGWTEGVQLMAPGAKYRFWMPPKLAYGERGLAGQIEPNSVLAFEVELLEIAGQGAPTHDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPG4</accession>
    <name>A0A0S2DPG4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phytase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_4944</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949433.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4944"/>
    <dbReference type="EnsemblBacteria" id="ALN60285">
        <property type="protein sequence ID" value="ALN60285"/>
        <property type="gene ID" value="GLE_4944"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4944"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4872"/>
    <dbReference type="OMA" id="QPYGLWV"/>
    <dbReference type="OrthoDB" id="1018030at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016158">
        <property type="term" value="F:3-phytase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003431">
        <property type="entry name" value="BP_Phytase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001258">
        <property type="entry name" value="NHL_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01436">
        <property type="entry name" value="NHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51662">
        <property type="entry name" value="BP_PHYTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51125">
        <property type="entry name" value="NHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595510" evidence="3">
        <location>
            <begin position="30"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="BPP" evidence="4">
        <location>
            <begin position="62"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="repeat" description="NHL" evidence="2">
        <location>
            <begin position="122"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="416" mass="44272" checksum="95B34BA543D0B970" modified="2016-02-17" version="1">MPKFSVLAAGLAAAATVAALVSCATPRAAGDAADAAPAIAADARPGDNEPDRRAAEAGDPLLARSGIDHRVVAEAFLTASTPEDNIDSPAVWRAPNGRLWLLATAKQGDGLAIYDGDNGDRVGQYGRGGAAPGQFRRPNGIAVFGDLAFVVERDNHRVQVLQLSLPTARSAQPGVADKRTPQLRPLATFGEGELQQPYGLWVRQRAPGTLEAIVTDAYMAGEDGNGDAIAPPLERLDRRLQRYELALGAGAPRVRHLGAFGDTSAEGAIRVPESVWGDPAHDRLLIAEEDLATGTALREYGLDGRYRGRTIGQGLFKAQAEGIALWQCADGSGYWIATDQYKDRSAFHVFDRASLRHLGAFAGRSVGNTDGVWLQQTGSVRFPDGAFYAVHDDQAVGAFDWRDIARALGLRARCES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPH6</accession>
    <name>A0A0S2DPH6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5157</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60498">
        <property type="protein sequence ID" value="ALN60498"/>
        <property type="gene ID" value="GLE_5157"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5157"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5080"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="50" mass="5654" checksum="7593C042AEAF669A" modified="2016-02-17" version="1">MRLAPVDRHDKRWPNVVTSARVLPTGTARFGRNPRQNVISGARRHVAAHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPI4</accession>
    <name>A0A0S2DPI4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Efflux pump membrane transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BV903_08105</name>
        <name evidence="9" type="ORF">FE772_25285</name>
        <name evidence="7" type="ORF">GLE_5225</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cell inner membrane</location>
            <topology evidence="2 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000016">
        <property type="protein sequence ID" value="OPD64497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949647.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5225"/>
    <dbReference type="EnsemblBacteria" id="ALN60566">
        <property type="protein sequence ID" value="ALN60566"/>
        <property type="gene ID" value="GLE_5225"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64497">
        <property type="protein sequence ID" value="OPD64497"/>
        <property type="gene ID" value="BV903_08105"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5225"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5143"/>
    <dbReference type="OMA" id="IVPMTML"/>
    <dbReference type="OrthoDB" id="145346at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042908">
        <property type="term" value="P:xenobiotic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004764">
        <property type="entry name" value="HAE1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00915">
        <property type="entry name" value="2A0602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="342"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="369"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="396"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="440"/>
            <end position="460"/>
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    <sequence length="1057" mass="113684" checksum="EB4B5EB4C1FEDE2F" modified="2016-02-17" version="1"> </sequence>
</entry>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
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            <dbReference type="PROSITE" id="PS50990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
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            <dbReference type="EMBL" id="ALN60631.1"/>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
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    <sequence length="247" mass="26947" checksum="D62A6614D70F78A3" modified="2016-02-17" version="1">MSASPARAASFVIALALAHAGAAPAQPSAAPGERYSAVDLTRLTGATATPLRKPMRSLRDLRYRELLRQRYDFSCGSAALASLLHYGYGLDVDEPALIEKMMAGADPREVVRNGFSMLDMKRYVEGIGMRAHGFRIDAEALYRLQMPVIALLDLRGYRHFVVIKGAAGGRVFVADPALGHRVMPQAEFERGWNGIVLAVVGDRPMRADSYLVGDRSSPALRRRGDALDRATAAPRAAEYALTLSDWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        </location>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="OPD65075.1"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ88</accession>
    <name>A0A0S2DQ88_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
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        </location>
    </feature>
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            <begin position="20"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="72" mass="7627" checksum="0F8645E2FDB3247D" modified="2016-02-17" version="1">MSPTHRTTLFAAFVAFAFAAGFAGSVAAAKPDCSPCVAIYDSCMARPDGNWEICAREHNLCAGPLGCRYLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQL8</accession>
    <name>A0A0S2DQL8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
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        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLE_5446</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
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            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949815.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5446"/>
    <dbReference type="EnsemblBacteria" id="ALN60787">
        <property type="protein sequence ID" value="ALN60787"/>
        <property type="gene ID" value="GLE_5446"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5446"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5362"/>
    <dbReference type="OMA" id="TERARMW"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Kinase-like_dom_sf"/>
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        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="424"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="106"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN60787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="906" mass="98686" checksum="3FE1582549883AE4" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQR6</accession>
    <name>A0A0S2DQR6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Site-specific recombinase, integrase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_5494</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949847.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
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    <dbReference type="EnsemblBacteria" id="ALN60835">
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        <property type="gene ID" value="GLE_5494"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5494"/>
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    <dbReference type="OMA" id="ENVKMGM"/>
    <dbReference type="OrthoDB" id="1791095at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA_bind_recomb_sf"/>
    </dbReference>
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        <property type="entry name" value="DNA_bind_recombinase_dom"/>
    </dbReference>
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        <property type="entry name" value="Resolv_N"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="RECOMBINASE_DNA_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="11"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Recombinase" evidence="2">
        <location>
            <begin position="171"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="450" mass="50934" checksum="19D177E601C6DAEC" modified="2016-02-17" version="1">MSAPEISRRLRCAVYTRKSTEEGLEREYNSIEAQRDAGQAFIASRRAEGWIPVADDYDDAGYSAATLSRPALERLLDDIRAGKIDIVVTYKIDRLSRSLRDFHRLWEHMTAHEVEFVAVTQQFNTTDAMGRLMLNILLSFAEFDRELDVERARDKMIASKKKGLWMHGVPPLGYDLQNRRLVVDPKEAPLVRWIFQQVAAGMPTAKLVAALRERGATSKVWTTRNGRQIVGKPIAKSLLYKMLANRTYVGELRHGTQWFPDSHEAVIDPELWAKAQAATATRPRALPSPDAPKIPFPLRGLVFAADGRAMTPWHTTKRNGRTYRYYVHTRALHESAKLLKLPRVPAGELEAAVIEQLRSVLRAPELISAILPQAVALDASLDEPQIMVAMLRLHEIWGYLAGHEQAQMLQLLIERIVVHEDRAELRLRPLGLTTFVANLSSTQPLRCPHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAH7</accession>
    <name>A0A0S2DAH7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNase_H_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0082</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0082"/>
    <dbReference type="EnsemblBacteria" id="ALN55441">
        <property type="protein sequence ID" value="ALN55441"/>
        <property type="gene ID" value="GLE_0082"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0082"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.87"/>
    <dbReference type="OMA" id="MIGAADW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038720">
        <property type="entry name" value="YprB_RNase_H-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13482">
        <property type="entry name" value="RNase_H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase_H_2" evidence="2">
        <location>
            <begin position="213"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="403" mass="42961" checksum="BF7401F79E25858D" modified="2016-02-17" version="1">MSLDLAKLRALQKQAGRSDAMATERPARERDTAGATAFAGPRRALPAAPMLDAATAAASLAAVPDTAAPTANAAAASATHRVAAVADASGADAIFGPDGLAPSRPQRTDLDALRRLIALRERKPAGAATPASRAPSAGARDRAPTARAPAHTATPVHAPALRDRPIDRSLPGEEIAPGLHLIQAHLPLPGPREALSLAFAKRPDECLDPRRLLFFDTETTGLAGGTGTRAFMIGAADWHDDPVLGDGLRIRQLMISTLSAEAAMLREFARWLAPDTVLSSYNGRCYDAPLLNTRYRLARIANPLSGLDHVDLLFPARRLYRGVWENCRLATLERELLRILREDDLPGSQAPAAWLQFLRGGSSALLRRVAAHNHQDVVTLAELMQRLVLACAQAQAEAALQES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAK4</accession>
    <name>A0A0S2DAK4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945804.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55471">
        <property type="protein sequence ID" value="ALN55471"/>
        <property type="gene ID" value="GLE_0112"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0112"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.115"/>
    <dbReference type="OrthoDB" id="1401093at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="204" mass="22341" checksum="17A8479536C8DB31" modified="2016-02-17" version="1">MANKDELIGAARNPWWQAAAAVAATALVATIALGGFKPAKSKTKPLPSHAAGQRAQSGAMAVTPLRAWVARYRPGGRIEPNQLYLVLQADIENRTGRSFGSYDYLIKDLILVGPKREAVKADLPLAADDHTILGDLHPRLKQRVDLVWKLPPGYVYAPSQTFGLFGRDYKAKAYLNGESGWIQDSPKAKFELPVQDLRDRLVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAR7</accession>
    <name>A0A0S2DAR7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nitroreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0229</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949891.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0229"/>
    <dbReference type="EnsemblBacteria" id="ALN55588">
        <property type="protein sequence ID" value="ALN55588"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55588.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="392" mass="43323" checksum="6D45FA3231041DED" modified="2016-02-17" version="1">MRIRRCAILYLEPREDAGFDLASLLAGEAGIRRSLRWLALAPHLDAEVEVDAAARELLGRIGPGAWADAAPWLRTHPALVAELLDRGLLLCEDDADAGRREHRRRDEALRETHWWPPAALVHRLGRWQGLDSAAAMDAAEMNTAADLRRQLGAPPPHVVERGEAAHRQALPRQDDGEFERLLARRATCRNFDAGRALPLPAFARMLQRVFAAQAQVRIGDDAVFLKKHTPSGGGLHATEAYLIVRNVEGVAPGLYHYHPLEHALEPMPPPPAPLAQFAAQAVAGQRWFADAHALAVLAPRYARSFWKYRRHAKAYRALLLDVGHLSQTLYLSATELGLGAFVTSAINEADIERAFGLDPLADGPLAVCGFGWRGDRMRTSEFDPAGEVWRQE</sequence>
</entry>
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    <accession>A0A0S2DAT4</accession>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Fernandez C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 5">B25</strain>
        </source>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD62017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="124" mass="14103" checksum="E64E8ED8301A9CF9" modified="2016-02-17" version="1">MNRDELLGEIARLIVTDPKAGERPWDGYALIAWYGDGISRLNGFRYDKGQAGEPLTPSGVQVENRLEELRRVTQVQGKAPWRVCIIRINREAAEVAIDFEYEEPGRWYVTPDSAAEIAERVRPC</sequence>
</entry>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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            <end position="50"/>
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    </feature>
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        </source>
    </evidence>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
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    </evidence>
    <sequence length="274" mass="28316" checksum="1DC73071457598A8" modified="2016-02-17" version="1">MFDKVKRSWQLAKASASVLNSDRELLVFPVISAACVLVVLGTFLVPALALGVFEDGYSVGAALYAFAFYFCQYFVIVFCNCALVSAAMIRLEGGDPTPRDGLRAATARIGAIAGYAAIAATVGMLLNALKDRDNNIIVRLIGGALGAAWTMATFLVVPVLVAEDVGPVDAVKRSVAMFKRTWGESAAGMVGIGLACGMAMVALALGGFGLAWLLGQMSSALAVLIGALTVLALLGLAVYQSALGGVYSAALYRYAADGEVPAGFEGLSLESARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAZ8</accession>
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        <submittedName>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN55723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="255" mass="26889" checksum="2A4146FEEA7C933E" modified="2016-02-17" version="1">MTPIPPGSAFPAPTSADGARERERDEAHSAAGDVGADDPARTDLAETAAAAEGDATVPAYAPAAQAQSAGEPVATPSAAPPDAAPTPPPATTADGFPREGWQRLPARAIPLCTIDISLSLAVVFAIAAVIGGVLTVGRHAGLASGLTGALFGAGIGMWIGFRRYRNTLWRLDDHGFAVRRGVAWQRETIVPLTRVQHLDLKHGPLQRMRRLATLVVHTAGTRHSSVAIDHLDAGDAQRLRERLGRQLDHEDDQDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB18</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
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    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW24733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55730">
        <property type="protein sequence ID" value="ALN55730"/>
        <property type="gene ID" value="GLE_0372"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242164" evidence="1">
        <location>
            <begin position="23"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="150" mass="16321" checksum="74413084D9FEBFB4" modified="2016-02-17" version="1">MKIVCTGLLLLAAVSASGTAVAQACPGKLIAVKDIRNWDRADGPKLGELQLYWDSASNKNCARTVHTARTWNKPLKTSLIIQTCERKDFKNGYCTAGAKKYQNGVYKFQAGPLSLPGGNRCVWTQGGIDPYDPSRPASHFHTNTIAGHCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB81</accession>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0427</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946027.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55785">
        <property type="protein sequence ID" value="ALN55785"/>
        <property type="gene ID" value="GLE_0427"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0427"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.424"/>
    <dbReference type="OMA" id="WGAWRWQ"/>
    <dbReference type="OrthoDB" id="2059233at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="309" mass="30809" checksum="6017AF0D82A70987" modified="2016-02-17" version="1">MESRKERPVAPAPLRRGKPLALIFGLVAVFVASGYLLLRGEDPPFDSAATVASADKPAAASAAPARPVAAATPPPATSASTVPAPTMPAPALPATSTGAIVEPAKIVLDDDNPFDPGEPATKPAAKPAADAPRQVASATPPKAGAKPPIAAARTASAAGKRRGETKNNDDGLMAVLLGNIDTDAESGGKRKAKARNRNAKEDQDALEQLIRKVNADSAAEAKKNAAASAVAAKSAAAAGKTAAKPVAAGNAKSGAKSAKAAETAAPAAPANPVQASLRKCPKANTARGLQCRQKICAKYAGQDPACPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB85</accession>
    <name>A0A0S2DB85_LYSEN</name>
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        <submittedName>
            <fullName evidence="6">Peptidase, families S8 and S53/proprotein convertase P-domain protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FE772_02885</name>
        <name evidence="6" type="ORF">GLE_0421</name>
    </gene>
    <organism evidence="6 8">
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        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="RefSeq" id="WP_057946022.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55779">
        <property type="protein sequence ID" value="ALN55779"/>
        <property type="gene ID" value="GLE_0421"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0421"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.418"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04059">
        <property type="entry name" value="Peptidases_S8_Protein_convertases_Kexins_Furin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034182">
        <property type="entry name" value="Kexin/furin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002884">
        <property type="entry name" value="P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
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    <dbReference type="InterPro" id="IPR036852">
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    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01483">
        <property type="entry name" value="P_proprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
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        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
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    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033243120" evidence="4">
        <location>
            <begin position="27"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="domain" description="P/Homo B" evidence="5">
        <location>
            <begin position="463"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN55779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW24773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="589" mass="61546" checksum="6E70CCF5F98ED8A6" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBA0</accession>
    <name>A0A0S2DBA0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione-dependent formaldehyde-activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_0385</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
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    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0385"/>
    <dbReference type="EnsemblBacteria" id="ALN55743">
        <property type="protein sequence ID" value="ALN55743"/>
        <property type="gene ID" value="GLE_0385"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0385"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.382"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
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    </dbReference>
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        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="3">
        <location>
            <begin position="18"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN55743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="138" mass="15219" checksum="302152A4AE1E7E8A" modified="2016-02-17" version="1">MSATRIRSVGGTTIGPIHRATCHCGAVELELRLPHGIVDPHRCDCSLCRRRGAIVATVPLPDLRVVRGHAALRLYQFHTRTAKHYFCSVCGVYTHHQRRSDPNEYGVNVGCLEGVDPLWLDPVPVSDGVHHPSDSLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBB2</accession>
    <name>A0A0S2DBB2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_03145</name>
        <name evidence="1" type="ORF">GLE_0480</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946066.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55838">
        <property type="protein sequence ID" value="ALN55838"/>
        <property type="gene ID" value="GLE_0480"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0480"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.476"/>
    <dbReference type="OrthoDB" id="1567410at2"/>
    <dbReference type="Proteomes" id="UP000061569">
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24818.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="269" mass="30339" checksum="9A12C6D37AA0C93B" modified="2016-02-17" version="1">MSRIVYDRKRWSPNTPIFLNIRAGAGALARRQIADFGASWAAAVLGPDLKMPDAQQTNYPSVGGAPWDRVLAGGPPDTFVGDRPPGWIRGHLVNGRWHGRGDTWRNLVPLTTIANPNHATVEQYIDNYLDACRRYEEQAQRDHWYGVYYCVRASKNPLSDPSETDDAHLYAYAPEFIRIDWRAVRIDKPDDRTPLQALKNMDSYPIQPVASFSSDLRLPALPTPMYDRHVLPADNATGGELLADLPADFPTAQDNEFDDWFEIHQVVPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <end position="160"/>
        </location>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW24842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="922" mass="100266" checksum="06D3D1A1EBC3DFEF" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBL0</accession>
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        </submittedName>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </feature>
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    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="126" mass="12644" checksum="9204613964110A4B" modified="2016-02-17" version="1">MKNQIASLALLLSLGLAGPSHAAGIGDTGTVEESDGNISIEGTNIERSFVGTGGQLQIVGSNNRITVSGPLTSVTVDGAGNTVQVDSVKRVEITGAGSKVYYKSAPTKNGRPASSVTGIGSSVSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBV8</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 5">C3</strain>
        </source>
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    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
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                <person name="Fernandez C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946173.1">
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    </dbReference>
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        </location>
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            <end position="72"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64389.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW24932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="72" mass="7823" checksum="E9109CBB08C8777C" modified="2016-02-17" version="1">MKKQGTMQARTLAALAAFVFGSAAAMSAGANSYDCQLCWDNYHRCKNTPEFCDGQLQECLLRGDGKYPCPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        </location>
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        </location>
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            <end position="272"/>
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    </feature>
    <feature type="binding site" evidence="3">
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            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN55912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="544" mass="58351" checksum="A62917E2ECBA242A" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCQ7</accession>
    <name>A0A0S2DCQ7_LYSEN</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    <organism evidence="1 2">
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        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56288">
        <property type="protein sequence ID" value="ALN56288"/>
        <property type="gene ID" value="GLE_0930"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0930"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.918"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046116">
        <property type="entry name" value="DUF6053"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19523">
        <property type="entry name" value="DUF6053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="72" mass="7415" checksum="A7EF7F09BF7CDFAE" modified="2016-02-17" version="1">MRLFFCPGHGFCRTARGVGGRDFRPDAPSGCGRPSDPMLRAFVGGPSGPTLSGQVAAIRNKSIGPEGLPTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCV2</accession>
    <name>A0A0S2DCV2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_0810</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0810"/>
    <dbReference type="EnsemblBacteria" id="ALN56168">
        <property type="protein sequence ID" value="ALN56168"/>
        <property type="gene ID" value="GLE_0810"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0810"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.799"/>
    <dbReference type="OMA" id="PQSRTFA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="83"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="124"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="389" mass="40223" checksum="9ABD45145FAFD7EA" modified="2016-02-17" version="1">MRSRIFSASVADHACFGHVRPAGRFPVAGGSARLWPAVALVLALSACGGGKPAAEGARPVLVAKPGGAVAAISAYAGEVRAREESPLSFRVGGKLVERKVDVGAHVAAGQVLAVLDPGDLDAQTRAAQAQLAAAEAEYARARADQVRYEQLAKDQLVSRSTKDAQDAQAKAAQGQLNSARANWEVARNQSGYTQLRAPAAGVIASRAAEAGQVVAAGQQVFALAADGAREIAFAVPEGVIAAFKPGQQVQVELWSIPGKRWPGRVREVAPAADPASRTYAARVAVDAPAGTLELGQSARIYQANPTASGLSVPLAAVQQTGQGRAVFVADPRTGTVKLKPVATGPYGPERVPVRSGLGPDDWVVVAGGHLLRDGQKVAPVDRENHPVER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCZ1</accession>
    <name>A0A0S2DCZ1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946475.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1030"/>
    <dbReference type="EnsemblBacteria" id="ALN56388">
        <property type="protein sequence ID" value="ALN56388"/>
        <property type="gene ID" value="GLE_1030"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1030"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1018"/>
    <dbReference type="OMA" id="PHAHFAE"/>
    <dbReference type="OrthoDB" id="1270792at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013653">
        <property type="entry name" value="FR47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08445">
        <property type="entry name" value="FR47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="106"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="238" mass="25522" checksum="8AB0D4EF08D6DDEF" modified="2016-02-17" version="1">MSEGALDNPIWASLASRHRALALGAGGVARYPAEVAPFLGVASADAAEGADADAALEALVPAGDTALVLGVAPRPGPRWRLRHLADLAQMICRAPIAAPDAGDDGAPIVELDAARREDALALTALVYPHYFRPRTMELGRYFGIYQDGRLAAMAGERMGTDGYTELSAICTHPDFLGRGHARRLLASLVNDNHARGRIPFLHVSQENPRAVGLYLRNGFELRRAIPFWSLSRAEPARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD34</accession>
    <name>A0A0S2DD34_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1086</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56444">
        <property type="protein sequence ID" value="ALN56444"/>
        <property type="gene ID" value="GLE_1086"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1086"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1073"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="224" mass="24074" checksum="1EDAE41B00A109A2" modified="2016-02-17" version="1">MPEQDAMHATNAIAARFRPIWLCVLLAPACTGPTFTHAPAKENAAMTHSPADASAPVESGQLIARVLKLIDSIHGAADLAPDNIERQTGLPVRIHSADRTEYAASGRIDADWAYSLTSVSYRQGQAPSRLDFEFIDARADRRKPADPAAICALDVEGCRRALSRQGFEEVRLAQHAPDPGFGFRGVEPLSFVRGKVEVSLLAYEDADPGEARACVAGLQISVQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD54</accession>
    <name>A0A0S2DD54_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0943</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56301">
        <property type="protein sequence ID" value="ALN56301"/>
        <property type="gene ID" value="GLE_0943"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0943"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.931"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046116">
        <property type="entry name" value="DUF6053"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19523">
        <property type="entry name" value="DUF6053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="67" mass="6522" checksum="66B99043978B891C" modified="2016-02-17" version="1">MGFGSAAASAASHCFARNGAGWRRHAARVGGASAPMPSARVAAICNESVGTEVPPTTAQGGAGRSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD64</accession>
    <name>A0A0S2DD64_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_04060</name>
        <name evidence="5" type="ORF">D9T17_21540</name>
        <name evidence="4" type="ORF">FE772_06080</name>
        <name evidence="2" type="ORF">GLE_1107</name>
    </gene>
    <organism evidence="2 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">C3</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 9" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000007">
        <property type="protein sequence ID" value="OPD65272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000055">
        <property type="protein sequence ID" value="ROU04716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946530.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000055.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1107"/>
    <dbReference type="EnsemblBacteria" id="ALN56465">
        <property type="protein sequence ID" value="ALN56465"/>
        <property type="gene ID" value="GLE_1107"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65272">
        <property type="protein sequence ID" value="OPD65272"/>
        <property type="gene ID" value="BV903_04060"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1107"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1094"/>
    <dbReference type="OMA" id="LPIWNKG"/>
    <dbReference type="OrthoDB" id="1095037at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595004" evidence="1">
        <location>
            <begin position="25"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD65272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU04716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="280" mass="29673" checksum="5FCAC5D3542EEEB8" modified="2016-02-17" version="1">MSKLLRHLPLALTLALGVAAGAHAQAKRDTTYLPVWNQNNGKLEYLLQLEPADRAGARWKSGANTFDATVGLDANDGLGLVCDRKSGLAGAIGNLANHCLLAALDDDDHSNNRQFSAGASLSRPGGRVGVALGNGRETLPAWMSPNNRPSRVDQNTLTVYGQKNIGREAMVSIGGTWARAKLIPAGEMPNLADHWNSKSITVGAAYGNFGANIIGRVVDTPGQPGQWEGLGVGLTWRTPWSGQLTVGAENVVTRGKNPFAPGNGDKDEGTVPYVRYEQDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDA9</accession>
    <name>A0A0S2DDA9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Fructose-bisphosphate aldolase</fullName>
            <ecNumber evidence="3 4">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">fba</name>
        <name evidence="7" type="ORF">FE772_05540</name>
        <name evidence="6" type="ORF">GLE_0986</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the class I fructose-bisphosphate aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="3 4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946441.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="SMR" id="A0A0S2DDA9"/>
    <dbReference type="STRING" id="69.GLE_0986"/>
    <dbReference type="EnsemblBacteria" id="ALN56344">
        <property type="protein sequence ID" value="ALN56344"/>
        <property type="gene ID" value="GLE_0986"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0986"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.974"/>
    <dbReference type="OMA" id="DYREMLF"/>
    <dbReference type="OrthoDB" id="945470at2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00183"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029768">
        <property type="entry name" value="Aldolase_I_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000741">
        <property type="entry name" value="FBA_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11627">
        <property type="entry name" value="PTHR11627"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00274">
        <property type="entry name" value="Glycolytic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00158">
        <property type="entry name" value="ALDOLASE_CLASS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="4 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN56344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW25200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="336" mass="35956" checksum="C01CA70CA73BB524" modified="2016-02-17" version="1">MSIEQLAETAQAMVAAGKGIIAIDESTTTIAKRFAGVGIENTEENRRAYRELLLATPNLSDYISGAILFDETLRQSTKAGVPFAKHMADHGIIPGIKVDKGPQPLAGFPGEVVTEGLDGLRARLEEYYKLGARFAKWRAVINISDDIPSGTCIEANSHALARYAALCQEQGLVPMVEPEVIMDGSHDIDTCFEVTEVTLRSLFGALYEHSVLLEGTILKASMVLPGTTAAEQASVEDVAAATLQCLKSTVPATLPGIVFLSGGQSDEDATAHLNAMNQMGPNPWPLSFSYGRAMQSAALKLWSQDLVNNYAKAQQTVYERAKANGLAALGQWKSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDG6</accession>
    <name>A0A0S2DDG6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56588">
        <property type="protein sequence ID" value="ALN56588"/>
        <property type="gene ID" value="GLE_1231"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1231"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="42" mass="4032" checksum="14CEB2E00486DA84" modified="2016-02-17" version="1">MLGAGRGAGHGGVGRREGGCDDPTAVARRGGNDGPAFAHAVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDL5</accession>
    <name>A0A0S2DDL5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fe-S cluster assembly protein SufB</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">FeS assembly protein SufB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sufB</name>
        <name evidence="4" type="ORF">FE772_06805</name>
        <name evidence="3" type="ORF">GLE_1260</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0051 (ycf24) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946638.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1260"/>
    <dbReference type="EnsemblBacteria" id="ALN56617">
        <property type="protein sequence ID" value="ALN56617"/>
        <property type="gene ID" value="GLE_1260"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1260"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1244"/>
    <dbReference type="OMA" id="YYSAPKQ"/>
    <dbReference type="OrthoDB" id="635721at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010231">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000825">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037284">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045595">
        <property type="entry name" value="SufBD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19295">
        <property type="entry name" value="SufBD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="SSF101960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01980">
        <property type="entry name" value="sufB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SufBD_N" evidence="2">
        <location>
            <begin position="151"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="491" mass="54474" checksum="AE2F4AEB54AF4E0B" modified="2016-02-17" version="1">MATDIKTAPAQAGDIANREIHEQLGRRYEAGFVTDIESDSLPPGLDEDTVRALSAKKNEPQWMTEWRLAAYRHWLTMPMPHWAKLDIAPIDFQALSYYSAPKAKYNSLDEVPQELLDTYDKLGVPLHERARLAGVAVDAVFDSVSVGTTFRKELAEKGIIFCSMSEAIREHPELVRKYLGSVVPVGDNYFAALNSAVFSDGSFVFIPKGVRCPMELSTYFRINAGHTGQFERTLIVCEDQAYVSYLEGCTAPMRDENQLHAAVVELVALEDAQIKYSTVQNWYPGDEEGRGGIYNFVTKRGECRGARSKISWTQVETGSAITWKYPSCVLLGDDSVGEFYSVALTHHRQQADTGTKMIHVGKRTKSKIVSKGISAGRGQNTYRGLVKVEKNAAGARNHTQCDSLLIGKKCGAHTFPYIEVKHPDATVEHEATTSKISEDQLFYCRSRGIGEEDAVSMIVDGFCKSVFRELPMEFAVEAKKLLEVSLEGSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDP7</accession>
    <name>A0A0S2DDP7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PTS system fructose IIA component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_1185</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1185"/>
    <dbReference type="EnsemblBacteria" id="ALN56543">
        <property type="protein sequence ID" value="ALN56543"/>
        <property type="gene ID" value="GLE_1185"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1185"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1170"/>
    <dbReference type="OMA" id="VRAICYR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00006">
        <property type="entry name" value="PTS_IIA_man"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.510">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004701">
        <property type="entry name" value="PTS_EIIA_man-typ"/>
    </dbReference>
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        <property type="entry name" value="PTS_EIIA_man-typ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033887">
        <property type="entry name" value="PTS_IIA_man"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03610">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53062">
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PTS EIIA type-4" evidence="3">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="114" mass="12081" checksum="B59988E5F5A591D0" modified="2016-02-17" version="1">MLQVAGRLLNPLPLRAEAFEVPFDADLDQLLPQASAALRRVDGGDGVLLLTDLYGASPSNLAARVARLGTPVRRVSALNLPMLLRVMNYAELDLDQLPAVAAAGARNGVLHDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDQ4</accession>
    <name>A0A0S2DDQ4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TetR/AcrR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_06040</name>
        <name evidence="4" type="ORF">GLE_1098</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1098"/>
    <dbReference type="EnsemblBacteria" id="ALN56456">
        <property type="protein sequence ID" value="ALN56456"/>
        <property type="gene ID" value="GLE_1098"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1098"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1085"/>
    <dbReference type="OMA" id="YWHFANR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="44"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="226" mass="25101" checksum="BFCD94A5FA90E3A1" modified="2016-02-17" version="1">MNQPASNKPEPALDTASADAKSSAPSASAKSEGKADAKPERSGRLSADDWAQAALDLIAEQGVAAVAVEPLARRLGVTKGSFYWHFPSRDALLVAALERWEKVEQETVFGQLEPIPDPRQRLRSLFHLVAHEVKSHIIYSELLKALDHPAVQPVIGRVSERRLDYLTASFRQAGLSRTDAQHRARLLYAAYVGFLQLNLQLHQTRMQHDEFEAYVEHMMATLIPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDV0</accession>
    <name>A0A0S2DDV0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OMP_b-brl domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_21440</name>
        <name evidence="5" type="ORF">FE772_07205</name>
        <name evidence="3" type="ORF">GLE_1356</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000070">
        <property type="protein sequence ID" value="OPD61892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946713.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000070.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1356"/>
    <dbReference type="EnsemblBacteria" id="ALN56713">
        <property type="protein sequence ID" value="ALN56713"/>
        <property type="gene ID" value="GLE_1356"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61892">
        <property type="protein sequence ID" value="OPD61892"/>
        <property type="gene ID" value="BV903_21440"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1356"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1338"/>
    <dbReference type="OMA" id="ERANKDY"/>
    <dbReference type="OrthoDB" id="1264196at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594994" description="OMP_b-brl domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="2">
        <location>
            <begin position="7"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD61892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="217" mass="23618" checksum="5A1A6DBC699F1B08" modified="2016-02-17" version="1">MKKQLALALALAAASTSAAAYDRLSHTYVEAGFAHQQAEVPVLAPVGVTVDDMKANGGFINGSIAVGEKFYVFGGYQKGKDDSIAVNFEGFGKIGEFEIDAQQAHGGVGYGHQLSDRVQWTGEVSFLRTRFKAKGEDITQDTAEGDDYRASLGLRGNLARNFEGWIKANYTDGDMYDQEFSGTLGGLIKFNDNWGIVAEGEFGSDQKQYRLGVRWSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDW3</accession>
    <name>A0A0S2DDW3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_07275</name>
        <name evidence="2" type="ORF">GLE_1372</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946724.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56729">
        <property type="protein sequence ID" value="ALN56729"/>
        <property type="gene ID" value="GLE_1372"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1372"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1354"/>
    <dbReference type="OrthoDB" id="2189534at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="76" mass="8380" checksum="8746111E05D9C623" modified="2016-02-17" version="1">MALEALAEVAGAALRLCGRMLFEIVVEWLIYGTGRLLLWPFYRRKPPGDTACLCAGVGFWLLLLLAVAWSRTALNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE87</accession>
    <name>A0A0S2DE87_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_12650</name>
        <name evidence="5" type="ORF">D9T17_19475</name>
        <name evidence="4" type="ORF">FE772_08210</name>
        <name evidence="2" type="ORF">GLE_1577</name>
    </gene>
    <organism evidence="2 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">C3</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 9" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000031">
        <property type="protein sequence ID" value="OPD63564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000047">
        <property type="protein sequence ID" value="ROU05305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946890.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000047.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1577"/>
    <dbReference type="EnsemblBacteria" id="ALN56934">
        <property type="protein sequence ID" value="ALN56934"/>
        <property type="gene ID" value="GLE_1577"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63564">
        <property type="protein sequence ID" value="OPD63564"/>
        <property type="gene ID" value="BV903_12650"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1577"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1557"/>
    <dbReference type="OMA" id="TQIRFRV"/>
    <dbReference type="OrthoDB" id="1826274at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016890">
        <property type="entry name" value="UCP028520"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028520">
        <property type="entry name" value="UCP028520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU05305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="204" mass="22591" checksum="C31C43A1918FD805" modified="2016-02-17" version="1">MSIVVRDVREHELDSVLALNNAAGPAILPLDAARLRHFFDTAEYFRVAERDGTLAGFLIGVGSGAGHDSSNFRWFHERYPDFFYIDRIVVASRRRGGGVGRAFYADAQSYAELRYPQLACEVFLEGGNDPALLFHGSFGFREVGQHVMEEAGVRAAMLMKPLCSFEWVRQTYGDALPDAGWLTRPRVPVAPLQADAPRPTGTCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEP6</accession>
    <name>A0A0S2DEP6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L32</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rpmF</name>
        <name evidence="8" type="ORF">BV903_07260</name>
        <name evidence="10" type="ORF">D9T17_18825</name>
        <name evidence="9" type="ORF">FE772_08750</name>
        <name evidence="7" type="ORF">GLE_1688</name>
    </gene>
    <organism evidence="7 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 11">C3</strain>
        </source>
    </reference>
    <reference evidence="8 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">OH11</strain>
        </source>
    </reference>
    <reference evidence="9 14" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 14">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL32 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000013">
        <property type="protein sequence ID" value="OPD64678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000045">
        <property type="protein sequence ID" value="ROU05466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946979.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1688"/>
    <dbReference type="EnsemblBacteria" id="ALN57044">
        <property type="protein sequence ID" value="ALN57044"/>
        <property type="gene ID" value="GLE_1688"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64678">
        <property type="protein sequence ID" value="OPD64678"/>
        <property type="gene ID" value="BV903_07260"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1688"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1666"/>
    <dbReference type="OMA" id="GMHRAHD"/>
    <dbReference type="OrthoDB" id="2092354at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00340">
        <property type="entry name" value="Ribosomal_L32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002677">
        <property type="entry name" value="Ribosomal_L32p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044957">
        <property type="entry name" value="Ribosomal_L32p_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35534">
        <property type="entry name" value="PTHR35534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01783">
        <property type="entry name" value="Ribosomal_L32p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01031">
        <property type="entry name" value="rpmF_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD64678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW25742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROU05466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="64" mass="7202" checksum="BED3D430A5963A33" modified="2016-02-17" version="1">MAVQKSRVTPSRRGQRRAHDALSSKQLATDPTTGETHIRHHVTADGYYRGKKVIDTKSRVADEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEY5</accession>
    <name>A0A0S2DEY5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl-CoA thioesterase II</fullName>
            <ecNumber evidence="3">3.1.2.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tesB</name>
        <name evidence="3" type="ORF">GLE_1601</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the C/M/P thioester hydrolase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946912.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1601"/>
    <dbReference type="EnsemblBacteria" id="ALN56958">
        <property type="protein sequence ID" value="ALN56958"/>
        <property type="gene ID" value="GLE_1601"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1601"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1581"/>
    <dbReference type="OMA" id="SQVWFRT"/>
    <dbReference type="OrthoDB" id="990202at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006637">
        <property type="term" value="P:acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042171">
        <property type="entry name" value="Acyl-CoA_hotdog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003703">
        <property type="entry name" value="Acyl_CoA_thio"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11066">
        <property type="entry name" value="PTHR11066"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00189">
        <property type="entry name" value="tesB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="299" mass="33166" checksum="4B32BF9401661AAD" modified="2016-02-17" version="1">MTSSPVSELIELLSLERLEDNLFRGQSRDIGTKYVFGGQVLGQALSAAQATLDSPRAAHSLHAYFLKAGDIEAPIVYQADRTRDGGSFSVRRVTAIQHGQPIFFLAASFQVEQDGGEHQLSMPEVPKPEDIAPAPPVPPQVMATLPTKVQRWLSRQGPFEFRHVYPRDELNPPKRPPYQQVWFRLSERVGDAPELHRALLAYASDFHLLGTATFPHGISYYQPNVQMASLDHALWFHRPFRADEWLLYSIDSPSAQGARGLARGQIYDRDGRLVASTAQEGLIRVVADPGAAAHVPAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF57</accession>
    <name>A0A0S2DF57_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57056">
        <property type="protein sequence ID" value="ALN57056"/>
        <property type="gene ID" value="GLE_1700"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1700"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1678"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="41" mass="4937" checksum="845A122184B283C5" modified="2016-02-17" version="1">MSRDDKPPSRAFVRKRPSYFLLSARQKKVAKEKRLFKVKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFA5</accession>
    <name>A0A0S2DFA5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1634</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1634"/>
    <dbReference type="EnsemblBacteria" id="ALN56991">
        <property type="protein sequence ID" value="ALN56991"/>
        <property type="gene ID" value="GLE_1634"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1634"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1614"/>
    <dbReference type="OMA" id="RDWPYLY"/>
    <dbReference type="OrthoDB" id="1983082at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="198" mass="22637" checksum="BA0FAF3F5AA73F6A" modified="2016-02-17" version="1">MPTIRSYTGAEIAPYLNAIAALRIAVFRDWPYLYDGDAAYEAQYLQVYRDSWRGVAVLAFDGERIVGASTGLPLIDEMAEIRAAFDGHAVQAQHVFYCGESVLLPEYRGLGVGHRFFDAREAHARALGDFRWTGFCAVEREPGDPRRPPFHRGNEAFWKKRGYTHRPELVAKLPWNEVGRGEREHALSFWLRPLERAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFG0</accession>
    <name>A0A0S2DFG0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_08920</name>
        <name evidence="2" type="ORF">GLE_1725</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947009.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57080">
        <property type="protein sequence ID" value="ALN57080"/>
        <property type="gene ID" value="GLE_1725"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1725"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1703"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="114" mass="12196" checksum="1CCB1B983E6AAE8C" modified="2016-02-17" version="1">MKADAAARRWRIASWLAAAASLALPAAAYLLQKRDLDAAMHTHHGYVCGLPYLAAMLSSVLFAAVLSLAAMLCGWRAWRRLPPPRSIARTLEVAAVGAALWLLLLLAGAISALY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFT4</accession>
    <name>A0A0S2DFT4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HTH-type transcriptional activator AmpR</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">LysR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ampR</name>
        <name evidence="4" type="ORF">FE772_10325</name>
        <name evidence="3" type="ORF">GLE_2035</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947232.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2035"/>
    <dbReference type="EnsemblBacteria" id="ALN57385">
        <property type="protein sequence ID" value="ALN57385"/>
        <property type="gene ID" value="GLE_2035"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2035"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2000"/>
    <dbReference type="OMA" id="TNNNRVD"/>
    <dbReference type="OrthoDB" id="846433at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="290" mass="31243" checksum="9C09A6B926B91864" modified="2016-02-17" version="1">MAHTRINLGALKAFEAAARALSLTRAADELNVTQAAVSHQVRLLENQLGVELFRRLPRGLALTDEGLGLLPAIQEAFDRIDSALDRVGDGLAREVVHVGAVGTFASGWLLPRLAEFARLHPSVDVRVSTHNNRVDPAAEGLDYAVRFGRGTWPGMESKFLRAAPLTPLCTPAIAQQLRDPAELARFPLLRSYFVDDWRLWFEAAHAVPCGPINGAIFDSSVTMVQCALQGLGVALAPPSMFAREIAQGLLVQPFDTALDAGGYWLTRLALKPAGDGASAFAGWLERACAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGK6</accession>
    <name>A0A0S2DGK6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">T5orf172 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947481.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57713">
        <property type="protein sequence ID" value="ALN57713"/>
        <property type="gene ID" value="GLE_2364"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2364"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2325"/>
    <dbReference type="OMA" id="PEHIWAW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018306">
        <property type="entry name" value="Phage_T5_Orf172_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10544">
        <property type="entry name" value="T5orf172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00974">
        <property type="entry name" value="T5orf172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T5orf172" evidence="1">
        <location>
            <begin position="27"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="209" mass="23603" checksum="799B1037F357DDEF" modified="2016-02-17" version="1">MSFLRSREPERPAGASEGRCFVYVLPCAYEDLLKIGHSRNPLERAQALQPRYFEFFDLDRAFAVEVDKVREARALEHALHARLREHNAPAPLTVRAQAAGLGEWYRGAWTQLQDEAARWQAQGHRLHRPLSAWFARELVGQGDALYARAEALLAQLQGDTAALDDPALAPLRRNLLDTLDAHRALAGDLDRRLPAALLEWYRRGGRPVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGR8</accession>
    <name>A0A0S2DGR8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NDP-N-acetyl-D-galactosaminuronic acid dehydrogenase</fullName>
            <ecNumber evidence="5">1.1.1.-</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="6">UDP-N-acetyl-D-mannosamine dehydrogenase</fullName>
            <ecNumber evidence="6">1.1.1.336</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">wecC</name>
        <name evidence="6" type="ORF">FE772_11365</name>
        <name evidence="5" type="ORF">GLE_2254</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.-" evidence="5"/>
    <dbReference type="EC" id="1.1.1.336" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947404.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2254"/>
    <dbReference type="EnsemblBacteria" id="ALN57603">
        <property type="protein sequence ID" value="ALN57603"/>
        <property type="gene ID" value="GLE_2254"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2254"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2219"/>
    <dbReference type="OMA" id="IELANTH"/>
    <dbReference type="OrthoDB" id="295459at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0089714">
        <property type="term" value="F:UDP-N-acetyl-D-mannosamine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028359">
        <property type="entry name" value="UDP_ManNAc/GlcNAc_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500136">
        <property type="entry name" value="UDP_ManNAc_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="SSF52413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh_C" evidence="4">
        <location>
            <begin position="323"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW26182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="418" mass="44903" checksum="764874A5F105E629" modified="2016-02-17" version="1">MSFDTVSVIGLGYIGLPTAAAFAAARKRVIGVDVTASVVDTINRGEIHIVEPDLDVAVRDAVAGGFLRASLKPEHADAYLIAVPTPFKGDHQPDLAYIEAAAKALAPVLQKGDLVVLESTSPVGATEQLAQWLADARSDLSFPQHVGEAADVNVAHCPERVLPGQVMRELIENDRVIGGMTPRCSQRAAELYKSFVRGQCIVTNARTAEMCKLTENAFRDVNIAFANELSMICDTLGINVWELVGLANRHPRVNILQPGPGVGGHCIAVDPWFIVDSAPEQARLIRTAREVNNGKPGWVMDKIDAAIKEAKAAGKQDKDLKIAVFGLAFKPDIDDLRESPALGIAVELAQRHPGPVLAVEPHIQALPSKLSSPNVVLSDLSTASREADIAVLLVDHKPFKEHAMPAHMKIVDTKGIWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGT8</accession>
    <name>A0A0S2DGT8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">UDP-glucose 4-epimerase</fullName>
            <ecNumber evidence="5 8">5.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BV903_01495</name>
        <name evidence="10" type="ORF">GLE_2487</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">B25</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>UDP-alpha-D-glucose = UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:22168"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="5.1.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.2" evidence="5 8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000003">
        <property type="protein sequence ID" value="OPD65697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947575.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2487"/>
    <dbReference type="EnsemblBacteria" id="ALN57836">
        <property type="protein sequence ID" value="ALN57836"/>
        <property type="gene ID" value="GLE_2487"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65697">
        <property type="protein sequence ID" value="OPD65697"/>
        <property type="gene ID" value="BV903_01495"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2487"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2449"/>
    <dbReference type="OMA" id="GEHLICN"/>
    <dbReference type="OrthoDB" id="1597849at2"/>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05247">
        <property type="entry name" value="UDP_G4E_1_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 8" id="KW-0520">NAD</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="9">
        <location>
            <begin position="8"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN57836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OPD65697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="331" mass="35192" checksum="01983D4087A5B42C" modified="2016-02-17" version="1">MNANRPILITGGAGYVGSHVALHLAERGERVVVLDDLSTGHARSVIGAELVIGDVGDRDTVARVLREHDIDTVVHLAGRTIAPESVRDPLRYYAGNTCATHNLLACCAQAGVSRFVFSSSAAVYGMPASGVASEDTPTAPINPYGASKLMSEWMLRDLSAASGLRYAVLRYFNVAGSDTRGRTGHRTRNATLLIKAACEVATGQRDCIAVYGTDFATPDGTGVRDYIHVDDLARAHADALDYLRGGGESIVLNCGYGRGASVREVLRAVERAHGAPIPVVEHPRRIGDAPSLIADAARIRQVLGWSPRCDDIDLIVASALAWERSLAAERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGX1</accession>
    <name>A0A0S2DGX1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Hydrolase, alpha/beta fold family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_12605</name>
        <name evidence="2" type="ORF">GLE_2508</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947593.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57857">
        <property type="protein sequence ID" value="ALN57857"/>
        <property type="gene ID" value="GLE_2508"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2508"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2471"/>
    <dbReference type="OMA" id="VELEWHE"/>
    <dbReference type="OrthoDB" id="1119700at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="28"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="262" mass="29234" checksum="9D086AB929D94551" modified="2016-02-17" version="1">MNIEQRVVRAWNGRINTRVDVCGSGPPLLFLHGESGHWDPFLDRLAQRYTVYAPDFPGTSPGAEQEIDELRDIWDLTLYFEELLDALGLESVAVAGHSIGGMFAAELAAHARARIRRLVLIAPAGLWRDDHPVPNWWSIPAAELPQRTVAQPDGLVGQIMFAVPRDRDAAIERVIRKTWALACAGKFTWPIPDKGLARRIHRISAPSLIVWGRQDRMIPPVYAEEFAARIGGARTLLVDNAGHIPQLEQMDQVGDAVMRFLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHC9</accession>
    <name>A0A0S2DHC9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_13700</name>
        <name evidence="2" type="ORF">GLE_2738</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947777.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58086">
        <property type="protein sequence ID" value="ALN58086"/>
        <property type="gene ID" value="GLE_2738"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2738"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2696"/>
    <dbReference type="OrthoDB" id="1840670at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033243130" evidence="1">
        <location>
            <begin position="22"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="361" mass="39279" checksum="1AC7F395985DE1C3" modified="2016-02-17" version="1">MRYTRLSAALLIGLALAACKAADPSAAEAPAAQAAAPAAAAPAKPVADPKQTAEAAFAALRKRVPDFERLGYEHLVGDLDGDGIDDVVVAYGEGTPDAQMATLKKWAAILSRADGPLLLPAADTADDCVYLDRIEQGKLYLQVPDICTAARPKTREYLTYAWNGKTLAKVAGESADARVRQRLGALADAFARKDKQAILRAFKFPIPLGTVPVQGTPLGDEAERNNDRIDRAMAERHFDSLFPAQRLADYALLLGQVRALEPKPDQEGGETAYGQRQQGAETEWFELRIDWDPDEDRDEGNEELIQARIEVSGGIGKDVKAEAKTLGEVLKREEDSRRVYEEMRLFLIDGELRIQLPNGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHH6</accession>
    <name>A0A0S2DHH6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_18710</name>
        <name evidence="4" type="ORF">FE772_13315</name>
        <name evidence="2" type="ORF">GLE_2657</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000052">
        <property type="protein sequence ID" value="OPD62388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947709.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000052.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2657"/>
    <dbReference type="EnsemblBacteria" id="ALN58005">
        <property type="protein sequence ID" value="ALN58005"/>
        <property type="gene ID" value="GLE_2657"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62388">
        <property type="protein sequence ID" value="OPD62388"/>
        <property type="gene ID" value="BV903_18710"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2657"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2616"/>
    <dbReference type="OMA" id="SAFVIFW"/>
    <dbReference type="OrthoDB" id="1964018at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="101" mass="10999" checksum="B6A5020AD09171D5" modified="2016-02-17" version="1">MILFLALTFVGIAISALCAFAIFWPLALVHLRDRHPALRGELGEAAFVAPAAWNWLLRQRYRGAGDRNLDGLATPARVSLLITFAALACAGLLWLLSLMVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHL0</accession>
    <name>A0A0S2DHL0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Biopolymer transport protein ExbD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">exbD</name>
        <name evidence="15" type="ORF">FE772_12755</name>
        <name evidence="14" type="ORF">GLE_2541</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">C3</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">The accessory proteins ExbB and ExbD seem to form a complex with TonB.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Cell membrane</location>
            <topology evidence="12">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the ExbD/TolR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947621.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2541"/>
    <dbReference type="EnsemblBacteria" id="ALN57890">
        <property type="protein sequence ID" value="ALN57890"/>
        <property type="gene ID" value="GLE_2541"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2541"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2502"/>
    <dbReference type="OMA" id="TQGKKDT"/>
    <dbReference type="OrthoDB" id="1940365at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014170">
        <property type="entry name" value="TonB_ExbD_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30558">
        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02803">
        <property type="entry name" value="ExbD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN57890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW26405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="141" mass="15396" checksum="2EE0D33FE3621530" modified="2016-02-17" version="1">MAIRTARHDEDALEEHHEINVTPFIDVMLVLLIVFMVAAPLATVDTPVELPASAAKPQPREPEPVFLSVQADLSLRLGEAAVTRESLAPALQRATGGDRERRIYLRADKRVAYGDLMQTMNALQTAGYLKIALVGLEPATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHN1</accession>
    <name>A0A0S2DHN1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2442</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2442"/>
    <dbReference type="EnsemblBacteria" id="ALN57791">
        <property type="protein sequence ID" value="ALN57791"/>
        <property type="gene ID" value="GLE_2442"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2442"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2405"/>
    <dbReference type="OMA" id="QRFAYNQ"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594800" evidence="1">
        <location>
            <begin position="26"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="37"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="371" mass="40174" checksum="FEF3F14C41CF0803" modified="2016-02-17" version="1">MLLNKLRVTAIIAAVLMSFPCLAPAATALQDANERARAYVRQTMAEQRIPGLQLAVIKDGRIVLSESYGYANVENKVPATPKTLFPINSATKSFTGVALMQLAQAGHVDLDAPASRYLDDLPVAWRPIRVRQLLGHTSGLPDIVDQRGLIGGGNEAAAWTAVKALPLDAPIGQRFAYNQTNYGLLAQIIVKQTRMPYEQYLAQRQFAVAGMPLTTFGDSYDLVPNAATIYSYTPRGTLAKNDNDRLSRWIYDMPYSLWAGGGIQTTAEELSHWLIAVSNGRLIPKDAVQRMWTPETLNDGSDGAWGAGWPVLQAAPPRQVAGIGGARAAFIVYPDDGLAIVVLTNLAGANPQRFIPKIAEFYVSPGSAAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-06-17" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHX3</accession>
    <name>A0A0S2DHX3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_14695</name>
        <name evidence="1" type="ORF">GLE_2947</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947932.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58295">
        <property type="protein sequence ID" value="ALN58295"/>
        <property type="gene ID" value="GLE_2947"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2947"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2909"/>
    <dbReference type="OMA" id="LWEECLF"/>
    <dbReference type="OrthoDB" id="1921706at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="181" mass="20173" checksum="F6CD6B9AD7B361F9" modified="2016-02-17" version="1">MQLQELAALAEWDDGDGLGRFERFVPMLGERVGFVLFPARGAAMAATEAMAHTVREVLALGPADLAAIQALLWEECDFSFRVADYGVDARPGESSLDAHLREFAVTGPADALARARLGEIHIDDGHSARFARLQYHTVAENLISVIVKDGRIVDYDDDGTHLPWFERDERYAHRRRRKVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI33</accession>
    <name>A0A0S2DI33_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947978.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3011"/>
    <dbReference type="EnsemblBacteria" id="ALN58359">
        <property type="protein sequence ID" value="ALN58359"/>
        <property type="gene ID" value="GLE_3011"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3011"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2972"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="240" mass="25959" checksum="838C28F0DF454F01" modified="2016-02-17" version="1">MNQAHTTTLVTGASRRIGRALAQACLARGERVVAHRRIADAVPEPFAAPVDAWCWDMLQPLDSLPAQDIDHLILSASLFERGHAWNALSADGGAASASAEERERFARHLQVNLLAPWELAVRLNARRPLRSVTMLLDTYLDRSFPGHAAYQVSRAAGAGLVRALAAELTPCRVNAVAPGTVLPSVRDPAQRAEQEDAIKARTLLGRIGAVEDVVDAAMYLRDAAYVTGEILRVDGGRFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIA3</accession>
    <name>A0A0S2DIA3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2918</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947909.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58266">
        <property type="protein sequence ID" value="ALN58266"/>
        <property type="gene ID" value="GLE_2918"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2918"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2880"/>
    <dbReference type="OrthoDB" id="2031983at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="148" mass="16448" checksum="BBF4C6EAA636DC49" modified="2016-02-17" version="1">MSSTLTMEIHRADLAYRRRSLWLLLAIAAGCALALWQLHGWLQSVQAHVAIADAAQARRWLRRALAGLALAPTAPLWLWGRGLRRLGRAAGEQRRFPPRDWKTYRDVRVLRGDAAATWASRTQRAGRAAQYAAAACVAAALAVWVWLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIA4</accession>
    <name>A0A0S2DIA4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2993</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58341">
        <property type="protein sequence ID" value="ALN58341"/>
        <property type="gene ID" value="GLE_2993"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2993"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2954"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="49" mass="5908" checksum="5924598FBCEE711A" modified="2016-02-17" version="1">MRRKRFTAAPLPRSLVNGRFRTHRFRELRRNSCGIHVSEAVYPQRLLWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DID6</accession>
    <name>A0A0S2DID6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2892</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58240">
        <property type="protein sequence ID" value="ALN58240"/>
        <property type="gene ID" value="GLE_2892"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2892"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2854"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="47" mass="4625" checksum="73EF3C07D4371A10" modified="2016-02-17" version="1">MLPGGGGGGGGGGGASRPFRACPEPARSQPGGYRPGFKRNAVTLVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DII4</accession>
    <name>A0A0S2DII4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fumarate hydratase class II</fullName>
            <shortName evidence="2">Fumarase C</shortName>
            <ecNumber evidence="2">4.2.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Aerobic fumarase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Iron-independent fumarase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 6" type="primary">fumC</name>
        <name evidence="6" type="ORF">GLE_2715</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(S)-malate = fumarate + H2O</text>
            <dbReference type="Rhea" id="RHEA:12460"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="EC" id="4.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; (S)-malate from fumarate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.</text>
    </comment>
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    </dbReference>
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        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0816">Tricarboxylic acid cycle</keyword>
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            <end position="358"/>
        </location>
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            <end position="122"/>
        </location>
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        </location>
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    <feature type="region of interest" description="Substrate binding" evidence="2">
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            <end position="157"/>
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        <ligand>
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            <position position="347"/>
        </location>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="489" mass="51117" checksum="1326F9C934389F5F" modified="2016-02-17" version="1">MASKRKTPARGERAPAGKTGGAAAGYRLEHDSMGELSVPAAALWGAQTQRAVQNFPISGQPMPREFIRALALVKAAAAQVNGGFGLLDPGAAEAIAQAAREVADGGFDAQFPIDVYQTGSGTSSNMNANEVIATLASRSGKHAIHPNDHVNLGQSSNDTIPTAIRVSAALAVHEHLLPALKHLRKTIERRAKELGRTVKTGRTHLMDAMPLTFGQEFGAWAAQLDSAQQRIEDALRRLRRLPIGGTAIGTGINADPRFGKAVAKALSAAGGVRFESAADKFEGLASQDDAVELSGQLSALAVALTKIANDLRWMNSGPLAGLGEIELPALQPGSSIMPGKVNPVIPEAMAMVCAQVMGHHTAITIAGQSGNFQLNVMLPLIAYDLLDSIRLLARAMPLLADSAIAGLKVREAHVREALDRNPILVTALNPIIGYEKAAAIAKRAYKEARPVLEVALQDSGLSEKQLRKLLDPAALTRGGIRAGGGGGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DII7</accession>
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        <submittedName>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
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        </location>
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        </location>
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        <source>
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        </source>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN58459.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="208" mass="23528" checksum="DA6AD4581B49C3C9" modified="2016-02-17" version="1">MYALYYTPGAASLVVHWLLLELDQPHELRAVDIAAREHKDASYLALNPNGVVPTLLVDGQPRYEAAALAMLLADRHGDGAFAPAPADPQRAEYLQWMFNLTATLQAPLRLWWYPGDLQCDDEAVRRGARARFEAACERLDAHLGAHGPYLLGERLSAADFYLTMLMRWSRNLPRPAHDRPHLGALARRMKARPSFAELYRREGLEEWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIT2</accession>
    <name>A0A0S2DIT2_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    <organism evidence="2 3">
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        <lineage>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN58430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="38" mass="4151" checksum="814D79BFF5575659" modified="2016-02-17" version="1">MPFARIAAIWHKSIGPEVPPTRARNGPAGADCRHRSEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIU3</accession>
    <name>A0A0S2DIU3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_15440</name>
        <name evidence="1" type="ORF">GLE_3099</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW26828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948041.1">
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58446">
        <property type="protein sequence ID" value="ALN58446"/>
        <property type="gene ID" value="GLE_3099"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3099"/>
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    <dbReference type="OrthoDB" id="2020853at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="101" mass="10964" checksum="FE3435ABC33182B9" modified="2016-02-17" version="1">MPYEYQNDVNAKKIQKLADPEQAQAVLQTVSTLAGMTEPVDGDQVNQWLGLLADAPIVAQKVKSSHDMIEIYPGGKREPDRIFMTVDDGKVTIVAVGAASH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIZ4</accession>
    <name>A0A0S2DIZ4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutaredoxin</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Glutaredoxin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_16200</name>
        <name evidence="2" type="ORF">GLE_3273</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948169.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000096.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3273"/>
    <dbReference type="EnsemblBacteria" id="ALN58619">
        <property type="protein sequence ID" value="ALN58619"/>
        <property type="gene ID" value="GLE_3273"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3273"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3226"/>
    <dbReference type="OMA" id="CHKAKEL"/>
    <dbReference type="OrthoDB" id="2045232at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097573">
        <property type="term" value="F:glutathione oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011767">
        <property type="entry name" value="GLR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00195">
        <property type="entry name" value="GLUTAREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="1">
        <location>
            <begin position="58"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="135" mass="14510" checksum="F5BA91439110CBF6" modified="2016-02-17" version="1">MNFKSILTTILVVALALGLGVGAGYLVRNTGLLGGGGKGVEIVQGDYSAVYAKAGGDIVLYSLSTCPFCHKAKELLDKHNVRYVERVIDKDEAARKEADGLKINSVPVIYIGDQSMRGYDEAKLVELLDKHGKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ20</accession>
    <name>A0A0S2DJ20_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_3169</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TsaE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057950164.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3169"/>
    <dbReference type="EnsemblBacteria" id="ALN58515">
        <property type="protein sequence ID" value="ALN58515"/>
        <property type="gene ID" value="GLE_3169"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3169"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3124"/>
    <dbReference type="OMA" id="DAGFRDC"/>
    <dbReference type="OrthoDB" id="1827295at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003442">
        <property type="entry name" value="T6A_TsaE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02367">
        <property type="entry name" value="TsaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00150">
        <property type="entry name" value="T6A_YjeE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="174" mass="18073" checksum="2884887F61D3926E" modified="2016-02-17" version="1">MSHDVLSELRLHLADADATDALGAALAAARAHLPANAPALHVHLHGDLGAGKSTLARALLRALGVQGAIRSPTYTLVERYGLNDGGEAWHLDLYRIGDAGELEFLGLDGGEASLWLIEWPERGRGWLPPADLRIDLAVDGAGRSARLQAASAAARAWLDGVAAMGATAAYTGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ25</accession>
    <name>A0A0S2DJ25_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Phosphate transport system permease protein PstA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pstA</name>
        <name evidence="10" type="ORF">BV903_20460</name>
        <name evidence="11" type="ORF">FE772_16400</name>
        <name evidence="9" type="ORF">GLE_3316</name>
    </gene>
    <organism evidence="9 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">C3</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000062">
        <property type="protein sequence ID" value="OPD62057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948202.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000062.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3316"/>
    <dbReference type="EnsemblBacteria" id="ALN58662">
        <property type="protein sequence ID" value="ALN58662"/>
        <property type="gene ID" value="GLE_3316"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62057">
        <property type="protein sequence ID" value="OPD62057"/>
        <property type="gene ID" value="BV903_20460"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3316"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3266"/>
    <dbReference type="OMA" id="GIARWKA"/>
    <dbReference type="OrthoDB" id="1763210at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005672">
        <property type="entry name" value="Phosphate_PstA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00974">
        <property type="entry name" value="3a0107s02c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="28"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="270"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="8">
        <location>
            <begin position="85"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN58662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD62057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW26982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="301" mass="32197" checksum="07041D3A88800705" modified="2016-02-17" version="1">MSAVANKHDAAEAARHRTADSLYRRRRVVNAVSVVMACAAALFGLFFLGWILYTLISKGIGGINLALFTQNTPPPMQEGGLLNAFFGSAVMCLIAIVIGTPLGIAAGTWLAEYGAGRKMGTVVRFVNDILLSAPSIVLGLFVYTLVVMQTGGNFSALAGAIALAFIVLPVVVRTTDEMLRLVPPQMREAALSLGVPQWKVIMQVLYRSASAGIVTGVLLALARISGETAPLLFTAFGNQYWSHNVLQPMASVPVVMNQFAGSPYETWQTLAWAGALVLTFFVLVVSLLARALVLRNRISND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ74</accession>
    <name>A0A0S2DJ74_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3114</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948053.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3114"/>
    <dbReference type="EnsemblBacteria" id="ALN58461">
        <property type="protein sequence ID" value="ALN58461"/>
        <property type="gene ID" value="GLE_3114"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3114"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3071"/>
    <dbReference type="OrthoDB" id="2029962at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594833" evidence="2">
        <location>
            <begin position="24"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="138" mass="14659" checksum="B6A2796435259F1C" modified="2016-02-17" version="1">MRRLAFVPLAALWLAACSAPAPGAREATPAAAPAPTPAGPALRAVGTEPGWLAEVGPGESPTIRLELDYGERKLVVRDATRLEDVSGYTGYTADGVWVSLNYRREQCSDGMSDRDYIASVELQVGDRHYRGCAASLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ79</accession>
    <name>A0A0S2DJ79_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tetratricopeptide repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_3347</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3347"/>
    <dbReference type="EnsemblBacteria" id="ALN58693">
        <property type="protein sequence ID" value="ALN58693"/>
        <property type="gene ID" value="GLE_3347"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3347"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3297"/>
    <dbReference type="OMA" id="NLVVKCP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595287" evidence="3">
        <location>
            <begin position="41"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="332"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="406"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="451" mass="47307" checksum="EE81732645CA5A9A" modified="2016-02-17" version="1">MPAPAAPSASYGLPRSAPLRRAWRLAAAAVCLAWAACAGAAGVDGAGSNGATFNGATFNGTAPNGAGSNGAGSNGPIPHATGSDRALPDNAISVLDATRADRRIEAANVELRRDGQPPLAATSDAQGRAALDPAALRDPAARLSIRKPGYAELLAQCPCDGRRYALSPALASLDGLRVVLGWDAPGVDLDAHLSFPGNHVYFQRPRGLEARLDLDAADRRRPETVTIARRRPGEAYTYAVHDFGHRQRPEADALARSGARVYVYVGQSLVRTYAVPAQPGNVWTVFRIDGEGRFEEIDRIAASRASADALGAELARAPGQAAAAAAVEGEDAVAANQRGEAAYRGGDLAAAIAAYQQAIELDPGYALAFSNLGLAYVRKGRAAEAIWTSRRAIALAKGPGAATIRAGAYYNIGKLYELDGQYERAMSNYLAAKREKPDKSYDEALQRVSGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJH2</accession>
    <name>A0A0S2DJH2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3444</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58789">
        <property type="protein sequence ID" value="ALN58789"/>
        <property type="gene ID" value="GLE_3444"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3444"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3392"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="71" mass="7163" checksum="E53DA1F5D288B887" modified="2016-02-17" version="1">MEEPSLLWKSLRCCGRAFAVVGGPSGPTLSAPVAAPLAHRLHARDPSSGHRAAARPARVSPVTANGGAAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJI0</accession>
    <name>A0A0S2DJI0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="14">HSAF non-ribosomal peptide synthetase/polyketide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLE_3215</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">In the C-terminal section; belongs to the NRP synthetase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3215"/>
    <dbReference type="EnsemblBacteria" id="ALN58561">
        <property type="protein sequence ID" value="ALN58561"/>
        <property type="gene ID" value="GLE_3215"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3215"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3169"/>
    <dbReference type="OMA" id="WATGMIE"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043604">
        <property type="term" value="P:amide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020802">
        <property type="entry name" value="PKS_thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00824">
        <property type="entry name" value="PKS_TE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="4 10" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="13">
        <location>
            <begin position="547"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="12">
        <location>
            <begin position="1772"/>
            <end position="1846"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="12">
        <location>
            <begin position="2849"/>
            <end position="2924"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="10">
        <location>
            <position position="1806"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="10">
        <location>
            <position position="2884"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN58561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="3161" mass="345319" checksum="58CA8020FECAF24A" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJQ7</accession>
    <name>A0A0S2DJQ7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">DNA mismatch repair protein MutL</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">mutL</name>
        <name evidence="9" type="ORF">GLE_3165</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948091.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3165"/>
    <dbReference type="EnsemblBacteria" id="ALN58511">
        <property type="protein sequence ID" value="ALN58511"/>
        <property type="gene ID" value="GLE_3165"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3165"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3121"/>
    <dbReference type="OMA" id="AHERIMY"/>
    <dbReference type="OrthoDB" id="764332at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032300">
        <property type="term" value="C:mismatch repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00149">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020667">
        <property type="entry name" value="DNA_mismatch_repair_MutL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="DNA_mismatch_repair_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014790">
        <property type="entry name" value="MutL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042121">
        <property type="entry name" value="MutL_C_regsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="PTHR10073"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01119">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08676">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00853">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118116">
        <property type="entry name" value="SSF118116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00585">
        <property type="entry name" value="mutl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_mis_repair" evidence="8">
        <location>
            <begin position="214"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="MutL_C" evidence="7">
        <location>
            <begin position="438"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="340"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN58511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="625" mass="67864" checksum="72B5B30391E564E7" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJS3</accession>
    <name>A0A0S2DJS3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF4150 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_16495</name>
        <name evidence="3" type="ORF">GLE_3335</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948220.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3335"/>
    <dbReference type="EnsemblBacteria" id="ALN58681">
        <property type="protein sequence ID" value="ALN58681"/>
        <property type="gene ID" value="GLE_3335"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3335"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3285"/>
    <dbReference type="OMA" id="RINRCTH"/>
    <dbReference type="OrthoDB" id="1509354at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025425">
        <property type="entry name" value="Tox_PAAR-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13665">
        <property type="entry name" value="DUF4150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4150" evidence="2">
        <location>
            <begin position="23"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="507"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="529" mass="57135" checksum="647DF4E52D2DB072" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJU8</accession>
    <name>A0A0S2DJU8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF3325 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_17515</name>
        <name evidence="2" type="ORF">GLE_3557</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3557"/>
    <dbReference type="EnsemblBacteria" id="ALN58901">
        <property type="protein sequence ID" value="ALN58901"/>
        <property type="gene ID" value="GLE_3557"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3557"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3501"/>
    <dbReference type="OMA" id="GMDRHHE"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021762">
        <property type="entry name" value="DUF3325"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11804">
        <property type="entry name" value="DUF3325"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="110" mass="11820" checksum="BCAEA2049B3A7E9F" modified="2016-02-17" version="1">MLWLGLCLGVAAWCLLSLGLEKHHQQVFAGAFRPARARLLRGAGWALLALDFALFVHGWGWAQGPIFWTAALIVSALAWTLAMTMAPKASTKIAAAAVLSAFVAMPFWIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJX0</accession>
    <name>A0A0S2DJX0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">bpX5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3491</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948329.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58836">
        <property type="protein sequence ID" value="ALN58836"/>
        <property type="gene ID" value="GLE_3491"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3491"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3436"/>
    <dbReference type="OMA" id="LPWVDGA"/>
    <dbReference type="OrthoDB" id="2027798at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045548">
        <property type="entry name" value="bpX5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19921">
        <property type="entry name" value="bpX5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="bpX5" evidence="2">
        <location>
            <begin position="2"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="139" mass="15106" checksum="07E0CC43FDD26562" modified="2016-02-17" version="1">MKWSWGPEPEPPPPQGAAGVGRAASRALLAALQALEPVRRGALALTANADVLVATGPGDALPWCEGVLYIAPREHAPGLWLPTTQRPQLPLDLLQRALARRHPQSPLLMLREPARLVPLHRALPASDELIAQIRARWQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKA0</accession>
    <name>A0A0S2DKA0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutathione hydrolase proenzyme</fullName>
            <ecNumber evidence="4">2.3.2.2</ecNumber>
            <ecNumber evidence="4">3.4.19.13</ecNumber>
        </recommendedName>
        <component>
            <recommendedName>
                <fullName evidence="4">Glutathione hydrolase large chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="4">Glutathione hydrolase small chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="7" type="primary">ggt</name>
        <name evidence="7" type="ORF">GLE_3529</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 4">
            <text>an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:59468"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="ChEBI" id="CHEBI:143103"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>an alpha-amino acid + an N-terminal (5-L-glutamyl)-[peptide] = 5-L-glutamyl amino acid + N-terminal L-alpha-aminoacyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:23904"/>
            <dbReference type="Rhea" id="RHEA-COMP:9780"/>
            <dbReference type="Rhea" id="RHEA-COMP:9795"/>
            <dbReference type="ChEBI" id="CHEBI:77644"/>
            <dbReference type="ChEBI" id="CHEBI:78597"/>
            <dbReference type="ChEBI" id="CHEBI:78599"/>
            <dbReference type="ChEBI" id="CHEBI:78608"/>
            <dbReference type="EC" id="2.3.2.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>glutathione + H2O = L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:28807"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:61694"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Sulfur metabolism; glutathione metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.</text>
    </comment>
    <comment type="PTM">
        <text evidence="4">Cleaved by autocatalysis into a large and a small subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the gamma-glutamyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.2" evidence="4"/>
    <dbReference type="EC" id="3.4.19.13" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3529"/>
    <dbReference type="EnsemblBacteria" id="ALN58873">
        <property type="protein sequence ID" value="ALN58873"/>
        <property type="gene ID" value="GLE_3529"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3529"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3473"/>
    <dbReference type="OMA" id="KATKNMF"/>
    <dbReference type="UniPathway" id="UPA00204"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036374">
        <property type="term" value="F:glutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102953">
        <property type="term" value="F:hypoglycin A gamma-glutamyl transpeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103068">
        <property type="term" value="F:leukotriene C4 gamma-glutamyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006750">
        <property type="term" value="P:glutathione biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006751">
        <property type="term" value="P:glutathione catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043138">
        <property type="entry name" value="GGT_lsub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000101">
        <property type="entry name" value="GGT_peptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043137">
        <property type="entry name" value="GGT_ssub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00066">
        <property type="entry name" value="g_glut_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00462">
        <property type="entry name" value="G_GLU_TRANSPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595286" description="Glutathione hydrolase proenzyme" evidence="6">
        <location>
            <begin position="25"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="562"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="584" mass="61910" checksum="BE81A8EF5BD82125" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKE0</accession>
    <name>A0A0S2DKE0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 8" type="primary">rplO</name>
        <name evidence="10" type="ORF">D9T17_09525</name>
        <name evidence="9" type="ORF">FE772_18555</name>
        <name evidence="8" type="ORF">GLE_3771</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">OH11</strain>
        </source>
    </reference>
    <reference evidence="9 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000023">
        <property type="protein sequence ID" value="ROU07200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948538.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000077.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3771"/>
    <dbReference type="EnsemblBacteria" id="ALN59115">
        <property type="protein sequence ID" value="ALN59115"/>
        <property type="gene ID" value="GLE_3771"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3771"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3715"/>
    <dbReference type="OMA" id="FKNINRV"/>
    <dbReference type="OrthoDB" id="1874945at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="L18e/L15P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_L15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005749">
        <property type="entry name" value="Ribosomal_L15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_L18e/L15P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934">
        <property type="entry name" value="PTHR12934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="SSF52080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01071">
        <property type="entry name" value="rplO_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L18e/L15P" evidence="7">
        <location>
            <begin position="28"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW27343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROU07200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="145" mass="15230" checksum="614E539A5A8E1D78" modified="2016-02-17" version="1">MRLNTLKPADGARQERTRVGRGIGSGLGKTAGRGHKGSFARSGKGKIKAGFEGGQMPMQRRLPKIGFRSKLAKDTAEVLLYQLDKLDAGDIDFAALKAAKLVPSTAKQAKIVKKGELTKKFVLKGVLATAGAKAAIEAAGGKVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKM3</accession>
    <name>A0A0S2DKM3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Coenzyme PQQ synthesis protein D</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Pyrroloquinoline quinone biosynthesis peptide chaperone PqqD</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Pyrroloquinoline quinone biosynthesis protein PqqD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pqqD</name>
        <name evidence="5" type="ORF">BV903_22885</name>
        <name evidence="6" type="ORF">FE772_18500</name>
        <name evidence="4" type="ORF">GLE_3758</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">C3</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">YC36</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer. Interacts with PqqE.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000077">
        <property type="protein sequence ID" value="OPD61588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948528.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000077.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3758"/>
    <dbReference type="EnsemblBacteria" id="ALN59102">
        <property type="protein sequence ID" value="ALN59102"/>
        <property type="gene ID" value="GLE_3758"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61588">
        <property type="protein sequence ID" value="OPD61588"/>
        <property type="gene ID" value="BV903_22885"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3758"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3702"/>
    <dbReference type="OMA" id="WVILAPE"/>
    <dbReference type="OrthoDB" id="2008640at2"/>
    <dbReference type="UniPathway" id="UPA00539"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018189">
        <property type="term" value="P:pyrroloquinoline quinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008792">
        <property type="entry name" value="PQQD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022479">
        <property type="entry name" value="PqqD_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041881">
        <property type="entry name" value="PqqD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05402">
        <property type="entry name" value="PqqD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03859">
        <property type="entry name" value="PQQ_PqqD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0884">PQQ biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD61588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW27332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="98" mass="10745" checksum="E49A512771516802" modified="2016-02-17" version="1">MSATIDAGSVLRFPVGVRLQHDRARERWVLQAPERVVELDEIAHAVLTHVDGRCDVEAIVAALAAEYGADAGEIYGDVIELFSSLLEKRMLAFAPRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKR9</accession>
    <name>A0A0S2DKR9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MFS transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Transporter, major facilitator superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BV903_19045</name>
        <name evidence="8" type="ORF">GLE_3901</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">B25</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000054">
        <property type="protein sequence ID" value="OPD62324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3901"/>
    <dbReference type="EnsemblBacteria" id="ALN59243">
        <property type="protein sequence ID" value="ALN59243"/>
        <property type="gene ID" value="GLE_3901"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62324">
        <property type="protein sequence ID" value="OPD62324"/>
        <property type="gene ID" value="BV903_19045"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3901"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3838"/>
    <dbReference type="OMA" id="PLNRQDY"/>
    <dbReference type="OrthoDB" id="961781at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="322"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="352"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="388"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="416"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="29"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD62324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="444" mass="47420" checksum="6A1F54F6A3D59D48" modified="2016-02-17" version="1">MNPPPPMHSDAVAAAPAGAPPLSRKDTRTLLLSALGGALEFYDFVIFVFLTETLRKLFFPVGTPEWLGTLQVYGIFAAGYLVRPIGGVIMAHFGDRSGRKRMFTLSVFLMALPTLFIGLLPTYAQIGIAAPLLLLALRIVQGIAIGGEVPGAWTFVAEHAPRGRVGFACASLSAGLTAGILIGSLVSTAVNTWLAPAQVLDWGWRAPFVLGGVFGFLAVYLRRWLSETPVFTAMRESRQLVRELPLKQVLREHRAGVVLSMLVTWLLTAAIVVIILMTPTIAQQAFKMEPSRAFLGNSLAAFFLTLSAIGGGWLVDRIGRGRALLIGSLGVLVSSFALYYDLNHGAHNFLLLYALAGVFVGVVGVIPAVMVAAFPAPVRFSGLSFSYNVAYAVFGAATPPLIGGYLAPHFGGMAPAYYVMAVALVGVAVSAYLLSNPRQQFHED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL08</accession>
    <name>A0A0S2DL08_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type IV pilus assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pilI</name>
        <name evidence="2" type="ORF">GLE_3960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3960"/>
    <dbReference type="EnsemblBacteria" id="ALN59302">
        <property type="protein sequence ID" value="ALN59302"/>
        <property type="gene ID" value="GLE_3960"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3960"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3897"/>
    <dbReference type="OMA" id="HFPRERN"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039315">
        <property type="entry name" value="CheW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22617">
        <property type="entry name" value="PTHR22617"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheW-like" evidence="1">
        <location>
            <begin position="33"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="181" mass="20301" checksum="C67243795027771B" modified="2016-02-17" version="1">MILKTPFDVLSDYERRSLAHVAGLPEQLDAPGLWRGVGYRIGARRLASTFAEVVEILSLPQLTQVPGAQPWMLGLANVRGSLLPIVDLKQFLEGERTVLHEGQRILLVRQPGGDVAVLIDELYGQRSFHEHNLLALEDAEALVHGRYAHFVERAYRVDDQAWGVFNLDRLARTPEFRQAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL93</accession>
    <name>A0A0S2DL93_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_19340</name>
        <name evidence="2" type="ORF">GLE_3941</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948663.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59283">
        <property type="protein sequence ID" value="ALN59283"/>
        <property type="gene ID" value="GLE_3941"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3941"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3878"/>
    <dbReference type="OrthoDB" id="1646081at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726814" evidence="1">
        <location>
            <begin position="24"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="218" mass="24811" checksum="09F14E5A50B20AE1" modified="2016-02-17" version="1">MRKLNGWIAVLTLALLGFGSAHAGEEENLLVFVGEKMSVAEFKPELPPNTVMMDAVFKAKFRVRQVVYGRYDDEVIEFDAYDHFGVPGFAEYPHSLLFVLRQDDGFVQLKYQYVPVFRTRSGEWNGCGPVRNRDDQGRRYLAKAQPVAFAEEAYLRLSPERPRELDAKSYPRRDFRIEGDRAYCLTGSSLRELFELKKQAALKDEGWFGGNGAAPGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL96</accession>
    <name>A0A0S2DL96_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF962 domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">DUF962 family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_14750</name>
        <name evidence="5" type="ORF">D9T17_08750</name>
        <name evidence="4" type="ORF">FE772_19335</name>
        <name evidence="2" type="ORF">GLE_3940</name>
    </gene>
    <organism evidence="2 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">C3</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 9" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000038">
        <property type="protein sequence ID" value="OPD63147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000022">
        <property type="protein sequence ID" value="ROU07390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948662.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000022.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3940"/>
    <dbReference type="EnsemblBacteria" id="ALN59282">
        <property type="protein sequence ID" value="ALN59282"/>
        <property type="gene ID" value="GLE_3940"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63147">
        <property type="protein sequence ID" value="OPD63147"/>
        <property type="gene ID" value="BV903_14750"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3940"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3877"/>
    <dbReference type="OMA" id="FRHPLYS"/>
    <dbReference type="OrthoDB" id="1928487at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009305">
        <property type="entry name" value="Mpo1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06127">
        <property type="entry name" value="DUF962"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU07390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="101" mass="11658" checksum="A1DD61CD79787BDB" modified="2016-02-17" version="1">MSNRFASFREFYPFYLSEHSNRTSRRLHFIGSCGVLALLALAIAQGRPWLLLAALVCGYGFAWVGHFFFEKNRPATFKHPLYSFAGDWVMFKDILTGKIKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLF5</accession>
    <name>A0A0S2DLF5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59415">
        <property type="protein sequence ID" value="ALN59415"/>
        <property type="gene ID" value="GLE_4073"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4073"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4015"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="38" mass="4155" checksum="8C0B49CAE06244D6" modified="2016-02-17" version="1">MRRRFDDRDSGPGSEPPELAPPMRLGAASPIRPDPHAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLT7</accession>
    <name>A0A0S2DLT7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Prepilin leader peptidase/N-methyltransferase</fullName>
            <ecNumber evidence="10">2.1.1.-</ecNumber>
            <ecNumber evidence="10">3.4.23.43</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">pilD</name>
        <name evidence="15" type="ORF">BV903_18495</name>
        <name evidence="16" type="ORF">FE772_20190</name>
        <name evidence="14" type="ORF">GLE_4118</name>
    </gene>
    <organism evidence="14 17">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">C3</strain>
        </source>
    </reference>
    <reference evidence="15 18" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 18">B25</strain>
        </source>
    </reference>
    <reference evidence="16 19" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 19">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Typically cleaves a -Gly-|-Phe- bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group, the methyl donor being S-adenosyl-L-methionine.</text>
            <dbReference type="EC" id="3.4.23.43"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the peptidase A24 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="10"/>
    <dbReference type="EC" id="3.4.23.43" evidence="10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000050">
        <property type="protein sequence ID" value="OPD62467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948799.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000050.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4118"/>
    <dbReference type="EnsemblBacteria" id="ALN59460">
        <property type="protein sequence ID" value="ALN59460"/>
        <property type="gene ID" value="GLE_4118"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62467">
        <property type="protein sequence ID" value="OPD62467"/>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="295" mass="32780" checksum="47814FFC1AA64E8D" modified="2016-02-17" version="1">MAFLDQNPGLGYPLAAGLGLLLGSFYNVVILRLPKRLEWQWKKDAREILELPEVYDPPPPGIVVERSHCPHCKHQLAWFENIPLFSYLALRGRCRHCKTPISMQYPAVEFITMLLMVACVARFGFGWQGFGAMVFTSFLIILSGIDLRTQYLPDSLTLPLMWLGIVAASDNLYFPVKPAVLGAIAGFGSLWLVNWIYKQYQVVVRRVKDPRDGMGGGDFKLLAAIGAWVGLKGVLPTILMSSLVGAVIGSIWLAIKGRDMGVPIPFGPYLAIAGWIVFFWGESLLQAYLSYSGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMA0</accession>
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        <submittedName>
            <fullName evidence="4">DUF962 domain-containing protein</fullName>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 5">C3</strain>
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    <reference evidence="3 6" key="2">
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            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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            <authorList>
                <person name="Feng T."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        <source>
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        <source>
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    <sequence length="165" mass="18587" checksum="18E56A44BCA713B8" modified="2016-02-17" version="1">MSTLAHSAAVADRPIDRWFASYSGDHVNATNQRIHVFAVPAILWSVIALLWCIPSPDPMFRAGVWAALPMFAAMLFYYRSSRALGLGMLVQFVLFALLTHWIAQTFGIRALLWTAVTVFVVAWIAQFIGHKIEGKKPSFLTDLTYLLIGPAWVLAKLYRKLGWSY</sequence>
</entry>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="62" mass="6480" checksum="BF9C4FA3E3287CE4" modified="2016-02-17" version="1">MRAQTERAKQAGETRLPARSRFDIGRRIDASAPPAIRGAGVTLPNRIEPNRIAAAAAAAVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMP1</accession>
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        </lineage>
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    <reference evidence="15 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">C3</strain>
        </source>
    </reference>
    <reference evidence="16 18" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10 11">
            <text>D-ribulose 5-phosphate = D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13677"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="EC" id="5.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="10 13">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 10 11">Belongs to the ribulose-phosphate 3-epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.1" evidence="7 10 11"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948936.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4288"/>
    <dbReference type="EnsemblBacteria" id="ALN59629">
        <property type="protein sequence ID" value="ALN59629"/>
        <property type="gene ID" value="GLE_4288"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4288"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4227"/>
    <dbReference type="OMA" id="WLQVDGG"/>
    <dbReference type="OrthoDB" id="1697639at2"/>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004750">
        <property type="term" value="F:D-ribulose-phosphate 3-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019323">
        <property type="term" value="P:pentose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00429">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02227">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026019">
        <property type="entry name" value="Ribul_P_3_epim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000056">
        <property type="entry name" value="Ribul_P_3_epim-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11749">
        <property type="entry name" value="PTHR11749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00834">
        <property type="entry name" value="Ribul_P_3_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001461">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01163">
        <property type="entry name" value="rpe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01085">
        <property type="entry name" value="RIBUL_P_3_EPIMER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01086">
        <property type="entry name" value="RIBUL_P_3_EPIMER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="13" id="KW-0170">Cobalt</keyword>
    <keyword evidence="9 10 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="10 14">
        <location>
            <begin position="146"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="179"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10 14">
        <location>
            <begin position="201"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10 12">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10 12">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 14">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13 14">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR001461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ALN59629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QCW27751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="226" mass="24174" checksum="223013604155557F" modified="2016-02-17" version="1">MTTQSTVIAPSILSADFARLGEEVDNVLKAGADWVHFDVMDNHYVPNLTIGPMVCEALRKHGVTAPIDVHLMVEPVDRIVPDFAKAGATTISFHPEASAHVHRTIQLIKSLGCKAGLVLNPGTPLEVLDWVLDDLDMVLLMSVNPGFGGQSFIPSALEKLRRVRERIDRSGRAIRLEIDGGVKADNIGEIAAAGADTFVAGSAIFNAPDYADTIGRMKAAVAAARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMP5</accession>
    <name>A0A0S2DMP5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Dipeptide epimerase</fullName>
            <ecNumber evidence="6">5.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">tfdDII</name>
        <name evidence="9" type="ORF">BV903_14100</name>
        <name evidence="11" type="ORF">D9T17_06330</name>
        <name evidence="10" type="ORF">FE772_22445</name>
        <name evidence="8" type="ORF">GLE_4601</name>
    </gene>
    <organism evidence="8 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 12">C3</strain>
        </source>
    </reference>
    <reference evidence="9 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">OH11</strain>
        </source>
    </reference>
    <reference evidence="10 15" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 15">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5 6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5 6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the mandelate racemase/muconate lactonizing enzyme family.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000036">
        <property type="protein sequence ID" value="OPD63262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000019">
        <property type="protein sequence ID" value="ROU07819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949172.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4601"/>
    <dbReference type="EnsemblBacteria" id="ALN59942">
        <property type="protein sequence ID" value="ALN59942"/>
        <property type="gene ID" value="GLE_4601"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63262">
        <property type="protein sequence ID" value="OPD63262"/>
        <property type="gene ID" value="BV903_14100"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4601"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4536"/>
    <dbReference type="OMA" id="RQRDICL"/>
    <dbReference type="OrthoDB" id="951991at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016855">
        <property type="term" value="F:racemase and epimerase activity, acting on amino acids and derivatives"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03319">
        <property type="entry name" value="L-Ala-DL-Glu_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034603">
        <property type="entry name" value="Dipeptide_epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013341">
        <property type="entry name" value="Mandelate_racemase_N_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02746">
        <property type="entry name" value="MR_MLE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MR_MLE" evidence="7">
        <location>
            <begin position="141"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for (R)-substrate epimerization" evidence="3">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for (S)-substrate epimerization" evidence="3">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR634603-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR634603-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR634603-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD63262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROU07819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="366" mass="39101" checksum="3EE4EAE6EC6F98F0" modified="2016-02-17" version="1">MKITDIRFGMLRVPLKTPFKTALRTVDTVEDIVVTIHTDTGHVGYGEAPATAPITGDTHGSIVEAIRKFISPRLIGQEIANLNRITGLIQGAIEKNSSAKAAVEIAVYDLFGQLYGAPLYKMLGGGDPVITTDLTISVDYIEKMVADSIAAVDRGFESLKIKVGKDIGVDIERVKAIYAAVEGRALLRLDANQGWTAKQAVYALQTLEDAGVRLELVEQPVKAQDLEGLKYVTDRVHTPIMADESVFGPVEVIDLIRMRAADIINIKLMKTGGLSKAIQIADIAAMYGVECMIGCMIETSISVAAAVHLAVAKSNVITKVDLDGPSLCAFNPVDGGVIFNESEITVTDAPGLGIREIRGLETLAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMQ2</accession>
    <name>A0A0S2DMQ2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4538</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59879">
        <property type="protein sequence ID" value="ALN59879"/>
        <property type="gene ID" value="GLE_4538"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4538"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4474"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="142" mass="15031" checksum="03BDCC4E1E83DFB3" modified="2016-02-17" version="1">MIRPAATATGSDHGRAPSGARSRIGGAGSREARSAAATNGPQAATPLPAPSFRRKPEPILTLLLLRCVGRRRAKSKWVPAFAGMTVLELLAWKTELREAPAQPTACRSPAAARPSRCRNPRPSSCFPAPRPAPLRNNPADPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMR9</accession>
    <name>A0A0S2DMR9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">ABC transporter, ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BV903_03280</name>
        <name evidence="7" type="ORF">FE772_21780</name>
        <name evidence="5" type="ORF">GLE_4463</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000006">
        <property type="protein sequence ID" value="OPD65329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949073.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4463"/>
    <dbReference type="EnsemblBacteria" id="ALN59804">
        <property type="protein sequence ID" value="ALN59804"/>
        <property type="gene ID" value="GLE_4463"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65329">
        <property type="protein sequence ID" value="OPD65329"/>
        <property type="gene ID" value="BV903_03280"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4463"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4400"/>
    <dbReference type="OMA" id="NICKFYS"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD65329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW27884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="230" mass="25141" checksum="A4678234C90CC015" modified="2016-02-17" version="1">MDTLVSINHLTKTYQRGPEKVEVLHGINLDIAKGDFVALMGPSGSGKSTLLNLIGGLDNPSGGEITVEGERIDRMSPGQLSQWRSRHVGFIFQFYNLMPALTAQKNVELPLLLSPLGAAQRKRNAEIALTLVGLAERRSHRPNELSGGQQQRVAIARAIVSDPTLLICDEPTGDLDRQSAEDILGLLRLLNREHGKTIVMVTHDPKAAEYATHTLHLDKGTLVEQQPDAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMU2</accession>
    <name>A0A0S2DMU2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF1311 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_23175</name>
        <name evidence="3" type="ORF">GLE_4766</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949299.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60107">
        <property type="protein sequence ID" value="ALN60107"/>
        <property type="gene ID" value="GLE_4766"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4766"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4699"/>
    <dbReference type="OMA" id="LPAKECE"/>
    <dbReference type="OrthoDB" id="33572at135614"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009739">
        <property type="entry name" value="LprI_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07007">
        <property type="entry name" value="LprI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242254" evidence="1">
        <location>
            <begin position="26"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="LprI" evidence="2">
        <location>
            <begin position="90"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="177" mass="19394" checksum="2C07F52376F760E4" modified="2016-02-17" version="1">MSKFTLLKHAALVTALSLGCGCASAARPGTGKAPEPAAPEEDCLVVGDTQTRELCFSRKPEAEIEECERMRPFACKPYRDMHRLDRELAALTRDLSARAQKRYAAYAEDDAAYLGDLSAYIDASGEAWAASRDADCLLEPFAQGMSRREAGGLTEACRVERTQARIARLKEIVSTFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMW2</accession>
    <name>A0A0S2DMW2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Amino acid deaminase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">D-amino acid deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_22520</name>
        <name evidence="3" type="ORF">GLE_4617</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DSD1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949185.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4617"/>
    <dbReference type="EnsemblBacteria" id="ALN59958">
        <property type="protein sequence ID" value="ALN59958"/>
        <property type="gene ID" value="GLE_4617"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4617"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4552"/>
    <dbReference type="OMA" id="YVSHDDG"/>
    <dbReference type="OrthoDB" id="1512472at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026956">
        <property type="entry name" value="D-ser_dehydrat-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042208">
        <property type="entry name" value="D-ser_dehydrat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14031">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01119">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-ser_dehydrat" evidence="2">
        <location>
            <begin position="318"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="429" mass="46986" checksum="A2B61EE779AB14AC" modified="2016-02-17" version="1">MNEALRALQSQTLLPGVKGLPLQAPLAQDRIAAQGYCVLDGRLSYPVAVLRQSTLDHNLRWMREFAERAGALLAPHGKTTMSPQLFQAQLEAGAWAITLATVPQLRVAHRFGVRRVLLANQPVAYADIESLAALLREDEGFEAWVLVDSSAGAARLNEVVRRHAPQRRLPVLVELGLSGGRTGARGIDAALALAGEVAAASHLRLAGIEGYEGLWTGADRAADLQCVQDLLAQMLDATRRCDRAGLFDGEEILISAGGSAYFDLVADAFAGLDGLSRPLRRVLRSGCYLTSDHGLYHGLQQEMRTRHGAEFRHGLQPALELWAMVQSRPEPGLALLTLGKRDASYDVELPRPLQWHRPGEPAPWPLREARIARMNDQHAYLELPPEHPLQVGDLIAVGISHPCTTFDKWPLMLLSDDSYRVVGAINTFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN00</accession>
    <name>A0A0S2DN00_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Molybdopterin-guanine dinucleotide biosynthesis-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4567</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949149.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4567"/>
    <dbReference type="EnsemblBacteria" id="ALN59908">
        <property type="protein sequence ID" value="ALN59908"/>
        <property type="gene ID" value="GLE_4567"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4567"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4503"/>
    <dbReference type="OMA" id="LFGAAHW"/>
    <dbReference type="OrthoDB" id="1432587at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTP_transf_3" evidence="1">
        <location>
            <begin position="5"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="197" mass="20096" checksum="B3BE86046BCE94F5" modified="2016-02-17" version="1">MDFAAVLLAAGASRRLGQPKQLLRRDGESLLRRGARLALASGAARTVVVLGARAERLGAELDGLAAQSVLNPDWQDGMASSLATAARALAGFDGAVLVLACDQPALELAHLLALRDGAAAAGCAATEHAGALGVPALISAQLWREATGVRGDRGFGAALAQAPDGAVWRLLAPELELDLDTPADVDAAIARGWLDPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN29</accession>
    <name>A0A0S2DN29_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4486</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59827">
        <property type="protein sequence ID" value="ALN59827"/>
        <property type="gene ID" value="GLE_4486"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4486"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4423"/>
    <dbReference type="OMA" id="FYETVHT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="163" mass="18175" checksum="4AB32DF187B808C5" modified="2016-02-17" version="1">MHLRALGPDEAPALLAIFRAAVRVTAARDYAPEQIEAWSPAQWPPAQCERWIERVRALHPFVADIDGVAAGYADLQDDGLIDHFYVSPDFARRGVGAALMAHLLAQARERGLRVVHSNVSRTAQPFFTRFGFDIVAQQRPVVRGVEVPNARMRAVLAEPEDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN63</accession>
    <name>A0A0S2DN63_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tetratricopeptide repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4623</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4623"/>
    <dbReference type="EnsemblBacteria" id="ALN59964">
        <property type="protein sequence ID" value="ALN59964"/>
        <property type="gene ID" value="GLE_4623"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4623"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4559"/>
    <dbReference type="OMA" id="AMANHIG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="414" mass="44984" checksum="4097FD2413F02CDE" modified="2016-02-17" version="1">MGSHLLDPKSYDSVKALRFNFLFTFVKPGTRTHGSMSAAPDFAALTARHQRLQQYLQADPDNLGLLADAASAAFDARHLDECDALIARYARHAAPTPSLRNLAGLSAMSASRFDEAETQFASLLTEFDDPQLRFNHAYAVAMQARYEQALQGLDDAVLEQVAEAIRLKMLCLYHLGRLDDVVELGERYAQHPQAGEQVRGLLATALFDADEFERAQHYAALAPDSVGGLTVLGLLALHEDDTATARQRFALALEADPASGRAQLGEGLACLAEHDFAAAAPRLDRAATLLRSHAGSWLSAGWAYLMAGQPAQARERFERSLQTDRGFAEATGALAVVDAFEGHDEQARHRAEVALRLDPNCLSATYARSLLLARGGREQEGAALYQQMLQRPLGEDGPSIAQLIARRASHGARD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN96</accession>
    <name>A0A0S2DN96_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cysteine hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Isochorismatase family protein</fullName>
            <ecNumber evidence="2">3.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_22770</name>
        <name evidence="2" type="ORF">GLE_4675</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.-.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949230.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4675"/>
    <dbReference type="EnsemblBacteria" id="ALN60016">
        <property type="protein sequence ID" value="ALN60016"/>
        <property type="gene ID" value="GLE_4675"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4675"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4611"/>
    <dbReference type="OMA" id="KHVHNAF"/>
    <dbReference type="OrthoDB" id="1442962at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="189" mass="20369" checksum="9A433C6AAF019F2F" modified="2016-02-17" version="1">MTATRQRVALIPIDVQRGFDYSPWGRRNNPDMEANGRRLLAAWRERGWPLIHVRHDSVQPGSSLSPGHPGNAFRDGFEPLPGEAVVAKSVNAAFIGTDLDLRLRRLGVDTVVLFGVSTDMCVSTTARMASNLGYRTVVIGDACFCFDLDDGAGATIAAEAISAAHLATLRAEFAQVLDTAEFLATLDAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNB0</accession>
    <name>A0A0S2DNB0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF2269 domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_22110</name>
        <name evidence="2" type="ORF">GLE_4528</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ALN59869">
        <property type="protein sequence ID" value="ALN59869"/>
        <property type="gene ID" value="GLE_4528"/>
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    <dbReference type="KEGG" id="lez:GLE_4528"/>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="157" mass="17660" checksum="079C3C310DC156A5" modified="2016-02-17" version="1">MAYLWVKWIHILSSTLLFGTGLGIAFFFWIAHKRGDAKVIAETARTVVIADACFTAPAVLVQFGTGVWLALYLGIPWSLFWLKTALILFFVVGACWLPVLWLQARARRLAAQAAAANAPLPASYHRTMFWWFWLGWPAFLSVVGIFWLMVLKPTAAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNI4</accession>
    <name>A0A0S2DNI4_LYSEN</name>
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        </submittedName>
        <submittedName>
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        </submittedName>
    </protein>
    <gene>
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        <name evidence="2" type="ORF">GLE_4942</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60283.1"/>
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    </dbReference>
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    <dbReference type="OMA" id="MPMITLY"/>
    <dbReference type="OrthoDB" id="2055010at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="142" mass="16342" checksum="3F60AFFE3A9A9097" modified="2016-02-17" version="1">MTTIRTLTGDTELRAVWPLVAQLRPEFDEDRFVAQMHRQIAQGCRATVVFDDDGAPRAFACWRVMEMLAVGLHVYVDDLIVDQTVRSRGYGKTMLDWLKAEAKRLGCARLQLDSGTQRQDAHAFYLRERLRIEAFHFGVKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNK9</accession>
    <name>A0A0S2DNK9_LYSEN</name>
    <protein>
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        </submittedName>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">FE772_23040</name>
        <name evidence="2" type="ORF">GLE_4740</name>
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        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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        </lineage>
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    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60081">
        <property type="protein sequence ID" value="ALN60081"/>
        <property type="gene ID" value="GLE_4740"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4740"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4674"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726589" evidence="1">
        <location>
            <begin position="22"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="293" mass="31834" checksum="4E68705EDEAD705B" modified="2016-02-17" version="1">MRALRTFAALALLALAPAASGCINEVGTDRSGRSFSPDWVLGDFLIQTMTPEPPDPNLAARRIAAARARPDFANLNDLGVLLIRQGKPIAAAELFVAVEKLYPGRAATAANLGTALELMGRDAAALRWIRMGIERDANEHARSEWLHVRILEAKIAAAKDPGWLQRHSILGLEFSSALVPPFPTRMPAGNAGSTLIGSDLDSGLSYQLHERVQFVKPPDPVVASLFRDWAILHLSGGAMENADALYTLAFRYGAPRDALSLKRQAHARQVVARARKQDERYGADCKLCDPPFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNQ8</accession>
    <name>A0A0S2DNQ8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4855</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4855"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4785"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595530" evidence="2">
        <location>
            <begin position="25"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="308" mass="32051" checksum="46CCD659972F5C44" modified="2016-02-17" version="1">MPSAPRHRIAAAVLACLAAGAAQATGAPAPPAADAPARPTAAQAAAAPARPTAAQAAAAGKPSGEVLIYRCTDARGQLSLRDTPCAGGERQQTVSMVRPVDPPPRPTAPAPASAPVAARAPAPATQVVVLRAPQPMYDCVRPDGSRYVSDNGDGNPRMMPLVDLGYGLPVYPNGSYSSGSYSRSEYSGGVSSHSSLGTGLPPPQGGVRVADSSTRIAIGGRHGHVSYSRNSGYVVPGGYDYGYGAYYGSQLVRDECHPLPQQEVCAQLRDQRWAGDRRYNSALQSERARITEEQRVIDARLNADCGAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNW8</accession>
    <name>A0A0S2DNW8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Response regulator transcription factor</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Transcriptional regulatory protein, C terminal-transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FE772_23100</name>
        <name evidence="6" type="ORF">GLE_4752</name>
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    <organism evidence="6 8">
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            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW28103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949288.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4752"/>
    <dbReference type="EnsemblBacteria" id="ALN60093">
        <property type="protein sequence ID" value="ALN60093"/>
        <property type="gene ID" value="GLE_4752"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4752"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4686"/>
    <dbReference type="OMA" id="VWGYDAY"/>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="124"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="124"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN60093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW28103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="225" mass="24309" checksum="B24196F460F43C91" modified="2016-02-17" version="1">MRVLLLEDQSDLRDAVAGRLRAHGHAVDEAGDLAEAESFVQSYAYGALVLDRTLPDGDALAALQRWRQRGIATPALFLTARDAVADRVEGFAGGADDYLVKPFSMDELVARIGAIGRRGGAIVPSTIRIADLEVDLGRREARRAGIALPLRPKEFALLQLLAERAGQAVPRQDILAACWGEEQQPASNAEEVLIATLRRKLGDPPLLRTVRGSGYRLDVPDAARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNY4</accession>
    <name>A0A0S2DNY4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">DNA mismatch repair protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mutL</name>
        <name evidence="2" type="ORF">FE772_23190</name>
        <name evidence="1" type="ORF">GLE_4768</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4768"/>
    <dbReference type="REBASE" id="132003">
        <property type="entry name" value="LenC3ORFAP"/>
    </dbReference>
    <dbReference type="REBASE" id="335679">
        <property type="entry name" value="LenYC36ORF23185P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60109">
        <property type="protein sequence ID" value="ALN60109"/>
        <property type="gene ID" value="GLE_4768"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4768"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4702"/>
    <dbReference type="OMA" id="YLFDHLW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="695" mass="78772" checksum="1C187DA77F871AAA" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNY6</accession>
    <name>A0A0S2DNY6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thioesterase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Thioesterase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_18310</name>
        <name evidence="5" type="ORF">D9T17_04420</name>
        <name evidence="4" type="ORF">FE772_24405</name>
        <name evidence="2" type="ORF">GLE_5034</name>
    </gene>
    <organism evidence="2 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">C3</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 9" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000049">
        <property type="protein sequence ID" value="OPD62489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000013">
        <property type="protein sequence ID" value="ROU08323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949503.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5034"/>
    <dbReference type="EnsemblBacteria" id="ALN60375">
        <property type="protein sequence ID" value="ALN60375"/>
        <property type="gene ID" value="GLE_5034"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62489">
        <property type="protein sequence ID" value="OPD62489"/>
        <property type="gene ID" value="BV903_18310"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5034"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4962"/>
    <dbReference type="OMA" id="GHIVIQE"/>
    <dbReference type="OrthoDB" id="1814691at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012660">
        <property type="entry name" value="YiiD_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09500">
        <property type="entry name" value="YiiD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02447">
        <property type="entry name" value="yiiD_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YiiD_C" evidence="1">
        <location>
            <begin position="13"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU08323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="152" mass="16369" checksum="FDF9BF58949835D3" modified="2016-02-17" version="1">MTFDAALQRLHTHYQSMPPVAAMNVGISGYDGRRLRLRAPLSHHVNDKGCAFGGSLASVMTLASWGLVSLGLELAELRAEVFVADSQIRYLAPLFGDLEVQAELADGADWDLFVQTLRGRGRARTGLVARALLPEGGVATEFTARYVAIAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP21</accession>
    <name>A0A0S2DP21_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LprI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949324.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60141">
        <property type="protein sequence ID" value="ALN60141"/>
        <property type="gene ID" value="GLE_4800"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4800"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4732"/>
    <dbReference type="OMA" id="WINELET"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009739">
        <property type="entry name" value="LprI_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07007">
        <property type="entry name" value="LprI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LprI" evidence="1">
        <location>
            <begin position="94"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="187" mass="20771" checksum="4D11B069B2EEAF7F" modified="2016-02-17" version="1">MEQLIFTVIGALLTWAFYFIQRIAERRGTVDAIERGKQLLALKQELDGAHTSVEELQRFESRLIGKAEHAARVADSYVGKAEAIARDQGDAAVSQADMNQQAVAELGREQARLDAVVAHLRDRLDGDGRAAFERVHDAWMAFREQHARFVAQSYSSGSVRPLIYAVTMESITVAWINELETQLGEGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPR6</accession>
    <name>A0A0S2DPR6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5056</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949521.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60397">
        <property type="protein sequence ID" value="ALN60397"/>
        <property type="gene ID" value="GLE_5056"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5056"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4984"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="73" mass="8372" checksum="E99BCE5F84D025CD" modified="2016-02-17" version="1">MLPLPLPLSLLLLLPFWPSLEAYAPRTRRARAWMRACAMGQDVPYGASPRKVLDLVAFDLKQAFFFGYFLLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPX0</accession>
    <name>A0A0S2DPX0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Catalase-related peroxidase</fullName>
            <ecNumber evidence="1">1.11.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">katB</name>
        <name evidence="8" type="ORF">FE772_25200</name>
        <name evidence="7" type="ORF">GLE_5204</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Has an organic peroxide-dependent peroxidase activity.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the catalase family.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949632.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5204"/>
    <dbReference type="EnsemblBacteria" id="ALN60545">
        <property type="protein sequence ID" value="ALN60545"/>
        <property type="gene ID" value="GLE_5204"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5204"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5123"/>
    <dbReference type="OMA" id="KINHTKG"/>
    <dbReference type="OrthoDB" id="1584770at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08153">
        <property type="entry name" value="srpA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024168">
        <property type="entry name" value="Catalase_SrpA-type_pred"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465">
        <property type="entry name" value="PTHR11465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000296">
        <property type="entry name" value="SrpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="SSF56634"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0349">Heme</keyword>
    <keyword evidence="1 3" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 7" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="Catalase" evidence="6">
        <location>
            <begin position="21"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="3">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR000296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000296-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000296-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN60545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW28457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="358" mass="38574" checksum="DE5FA02D6EBD1014" modified="2016-02-17" version="1">MNEPTAPPRPPFPLARWTLIALAVGGLAGAFAYVAGYLDPQRLTPARVVDQLQANGGVHPGYRRNHAKGVCVIGRFDSSGNAAPYSRAALFAAGARTPLVGRFALPGGNPYAPDGGVPIRSLALRLTQADGQQWRTGMNNMPVFPVATPQAFYEQLRATAPDPATGKPDPARQKAFFEAHPETAAFRAWIKDQKPSASYATDAYYGLNAFYFVGADGARHAVRWQVEPDNGAAAAPLGAQDVNTLAAELERRLNQAPLRWRLWATLAAPGDPVDDATQSWPAQRPRIDAGTVILERAQDQDSGECRDINYDPLVLPDGIVASADPLLPARSAAYAESYRRRTYEEARAGGRPPREAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ03</accession>
    <name>A0A0S2DQ03_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HAD family hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IA, variant 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_07950</name>
        <name evidence="3" type="ORF">FE772_25140</name>
        <name evidence="1" type="ORF">GLE_5190</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000016">
        <property type="protein sequence ID" value="OPD64470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949621.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5190"/>
    <dbReference type="EnsemblBacteria" id="ALN60531">
        <property type="protein sequence ID" value="ALN60531"/>
        <property type="gene ID" value="GLE_5190"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64470">
        <property type="protein sequence ID" value="OPD64470"/>
        <property type="gene ID" value="BV903_07950"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5190"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5110"/>
    <dbReference type="OMA" id="WWEAFRQ"/>
    <dbReference type="OrthoDB" id="1167152at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD64470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="226" mass="24748" checksum="7341E1FCAFFB1718" modified="2016-02-17" version="1">MPAPIRTTFLFDLDGTLVDSVYQHVLAWKQALDADGIPLSVWRIHRKIGMSGGLFTNILLRETGIDITPERVERLHKLHAQAYAAQATQIRPLPGAVELLAYLTDNGIPWAIATSGRMETARHNLVALGVDPERNVVITRDMVRYAKPDPDLFLAAADKLGADIEHSVVVGDSIWDLLAARRARALGVGLLSGGYGQDELERAGGFRVYEDPADLLKHIDEVAARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ05</accession>
    <name>A0A0S2DQ05_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Immunogenic 75 kDa protein PG4</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">TolB-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_24210</name>
        <name evidence="3" type="ORF">GLE_4994</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949470.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4994"/>
    <dbReference type="EnsemblBacteria" id="ALN60335">
        <property type="protein sequence ID" value="ALN60335"/>
        <property type="gene ID" value="GLE_4994"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4994"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4922"/>
    <dbReference type="OMA" id="FVAHWDG"/>
    <dbReference type="OrthoDB" id="821953at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
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        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726740" evidence="2">
        <location>
            <begin position="26"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="301" mass="32442" checksum="C78E37B89EB6A549" modified="2016-02-17" version="1">MRHARVWWIPSVLLVCAVASPPAAALNEFGIEGMGVVSTPHSEVRASVSPDGRRIVWGSDRPGGPGGRDLWQATLVDGRWQNPEPLPINSAAKDYDPMFSGDGRWLYFFSDRPGGLGGEDLYRAAVRPDGGYGPAENLGPGVNTPGREWAPAPSRDGRHLLFASDGRGGAGRQDLWIARWDGKAFVDPRPAPGINTAADEFDATWLGDGRAIVFTRSDDVNEQPVRLYVAQCDGKRYGEAVPLGLSFNTAEGFTYGPVIDWNKPGEMLLNGMAKAPKAGKQDIYRIAAPAVTGKDGCVDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ96</accession>
    <name>A0A0S2DQ96_LYSEN</name>
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        <submittedName>
            <fullName evidence="1">UPF0225 protein YchJ</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">FE772_00240</name>
        <name evidence="1" type="ORF">GLE_5393</name>
    </gene>
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        <name type="scientific">Lysobacter enzymogenes</name>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_5393"/>
    <dbReference type="EnsemblBacteria" id="ALN60734">
        <property type="protein sequence ID" value="ALN60734"/>
        <property type="gene ID" value="GLE_5393"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5393"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5308"/>
    <dbReference type="OMA" id="WLYVDGD"/>
    <dbReference type="OrthoDB" id="1472440at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="131" mass="14420" checksum="677AA3F98632438D" modified="2016-02-17" version="1">MTARLAPPAACPCDPSRRYAACCGPLHAGQAAATAAALMRSRYSAYVLGDLEYLRASWAARTCPETLEFDPAVRWLGLELKRQREDGDAAVVEFVARYRVGGGSAVRLHEVSRFERAEGRWVYVDGEFPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQG1</accession>
    <name>A0A0S2DQG1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_07930</name>
        <name evidence="5" type="ORF">D9T17_03770</name>
        <name evidence="4" type="ORF">FE772_25120</name>
        <name evidence="2" type="ORF">GLE_5186</name>
    </gene>
    <organism evidence="2 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">C3</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 9" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000016">
        <property type="protein sequence ID" value="OPD64467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000011">
        <property type="protein sequence ID" value="ROU08602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949618.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000011.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60527">
        <property type="protein sequence ID" value="ALN60527"/>
        <property type="gene ID" value="GLE_5186"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64467">
        <property type="protein sequence ID" value="OPD64467"/>
        <property type="gene ID" value="BV903_07930"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5186"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5106"/>
    <dbReference type="OrthoDB" id="2069316at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU08602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="59" mass="6427" checksum="C7C06BF5F3492D42" modified="2016-02-17" version="1">MNATATARTAPTAKTPATAAPVRHVHRQRDFGVGYGNSSGYASNRSYASNWVQPRFRFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQJ9</accession>
    <name>A0A0S2DQJ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inorganic anion transporter, sulfate permease family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_5443</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949813.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5443"/>
    <dbReference type="EnsemblBacteria" id="ALN60784">
        <property type="protein sequence ID" value="ALN60784"/>
        <property type="gene ID" value="GLE_5443"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5443"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5359"/>
    <dbReference type="OMA" id="TECQKIG"/>
    <dbReference type="OrthoDB" id="751256at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="PTHR11814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="124"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="198"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="314"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="370"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="6">
        <location>
            <begin position="425"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN60784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="546" mass="56807" checksum="9E4F162BF5DDEFC6" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQM6</accession>
    <name>A0A0S2DQM6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PepSY-associated TM helix</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_24040</name>
        <name evidence="2" type="ORF">GLE_5266</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000089">
        <property type="protein sequence ID" value="OPD61374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949677.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000089.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5266"/>
    <dbReference type="EnsemblBacteria" id="ALN60607">
        <property type="protein sequence ID" value="ALN60607"/>
        <property type="gene ID" value="GLE_5266"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61374">
        <property type="protein sequence ID" value="OPD61374"/>
        <property type="gene ID" value="BV903_24040"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5266"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5185"/>
    <dbReference type="OMA" id="VWNNVRH"/>
    <dbReference type="OrthoDB" id="1538348at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="237" mass="24937" checksum="CECE9ED3275F463D" modified="2016-02-17" version="1">MELADAYAVVKWLHIGLGAVALGGFWGAGLSRKGGALHRRAGQAFALAMAGIIVTGVPMAGYALHRGHPVTAAFLAYLLVITATGVWSGWRAIADKRDVRAYTGPVFVALAALSLASGAAMLALGLAKGHPLPIGFSAIGLGIGASMLRKRRNRDALAARPRWWMIEHYNAMIGNGVAVHIAFLGIGLPRLLPMLGGATLQQLAWFGPVAVALAAKLWADRRWGAQHNAAKKESAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA07</accession>
    <name>A0A0S2DA07_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0015</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55374">
        <property type="protein sequence ID" value="ALN55374"/>
        <property type="gene ID" value="GLE_0015"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0015"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.22"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="53" mass="5912" checksum="289E3D398A0F0A15" modified="2016-02-17" version="1">MPSRADCKMQHWPPSVRARREANLFVAKQPGEAPGFYGQLIGVLGSSLRTRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA88</accession>
    <name>A0A0S2DA88_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">Glycerol-3-phosphate acyltransferase</fullName>
            <shortName evidence="8">GPAT</shortName>
            <ecNumber evidence="5 8">2.3.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">plsB</name>
        <name evidence="11" type="ORF">GLE_0106</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>an acyl-CoA + sn-glycerol 3-phosphate = a 1-acyl-sn-glycero-3-phosphate + CoA</text>
            <dbReference type="Rhea" id="RHEA:15325"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57970"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="EC" id="2.3.1.15"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Peripheral membrane protein</topology>
            <orientation evidence="8">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the GPAT/DAPAT family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.15" evidence="5 8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0106"/>
    <dbReference type="EnsemblBacteria" id="ALN55465">
        <property type="protein sequence ID" value="ALN55465"/>
        <property type="gene ID" value="GLE_0106"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0106"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.110"/>
    <dbReference type="OMA" id="EVIYVPC"/>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="UniPathway" id="UPA00557">
        <property type="reaction ID" value="UER00612"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004366">
        <property type="term" value="F:glycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102420">
        <property type="term" value="F:sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016024">
        <property type="term" value="P:CDP-diacylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07993">
        <property type="entry name" value="LPLAT_DHAPAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00393">
        <property type="entry name" value="Glyc3P_acyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022284">
        <property type="entry name" value="GPAT/DHAPAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041728">
        <property type="entry name" value="GPAT/DHAPAT_LPLAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045520">
        <property type="entry name" value="GPAT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028354">
        <property type="entry name" value="GPAT_PlsB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12563">
        <property type="entry name" value="PTHR12563"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19277">
        <property type="entry name" value="GPAT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500064">
        <property type="entry name" value="GPAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000437">
        <property type="entry name" value="GPAT_DHAPAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03703">
        <property type="entry name" value="plsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="10">
        <location>
            <begin position="478"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="HXXXXD motif" evidence="8">
        <location>
            <begin position="483"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN55465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1007" mass="109766" checksum="E49DAF9CB1560413" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAJ1</accession>
    <name>A0A0S2DAJ1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55545">
        <property type="protein sequence ID" value="ALN55545"/>
        <property type="gene ID" value="GLE_0186"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0186"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.188"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="40" mass="4600" checksum="3D407C53A4994449" modified="2016-02-17" version="1">MRRRPRRRIDGPDLGRRARGIGRGQRRRPVPRSLPPAPGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAM5</accession>
    <name>A0A0S2DAM5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55578">
        <property type="protein sequence ID" value="ALN55578"/>
        <property type="gene ID" value="GLE_0219"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0219"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.221"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="68" mass="7381" checksum="E0D73B4592886C1B" modified="2016-02-17" version="1">MRWAAIPENGRGRPPRGTRSPVAAASPRPARLRCSIAVPAARPRRAGPCRHGRPKAEPGMRCFDDGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB01</accession>
    <name>A0A0S2DB01_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipopolysaccharide core biosynthesis glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0361"/>
    <dbReference type="EnsemblBacteria" id="ALN55719">
        <property type="protein sequence ID" value="ALN55719"/>
        <property type="gene ID" value="GLE_0361"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0361"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.358"/>
    <dbReference type="OMA" id="YTELWAL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="2"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="234" mass="26561" checksum="9BD3563E755E7853" modified="2016-02-17" version="1">MVDSHSADATVALAEAAGARVLQRRFDGFRSQKQFAVEQAAHDWVLCLDADERVGDELRASILAARDRGFDAAAGYRFARLSDYFGRFLRHGNAYPDRVLRLFDRRRGGWRGQREVHEAASVDGAVATLRGDLIHYPYRSLQQQLAKTERYARMMAEHEHARGKRATLAKLVLAPAWRFWRGYLLRGGFRDGWHGLVYAYVRANYVRQKTIMLWMLGNGQPVVTPERGAGDGKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB14</accession>
    <name>A0A0S2DB14_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide repeat domain protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_18855</name>
        <name evidence="4" type="ORF">FE772_02485</name>
        <name evidence="2" type="ORF">GLE_0336</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000053">
        <property type="protein sequence ID" value="OPD62354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945962.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000053.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55694">
        <property type="protein sequence ID" value="ALN55694"/>
        <property type="gene ID" value="GLE_0336"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62354">
        <property type="protein sequence ID" value="OPD62354"/>
        <property type="gene ID" value="BV903_18855"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0336"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.333"/>
    <dbReference type="OrthoDB" id="1660915at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="267" mass="27941" checksum="F5236C866CC6C424" modified="2016-02-17" version="1">MDAIADPRTILAAGAYGTALLFFVYGGYVLQKARSAEQSRNVRWYLGIGAVVALAMIGFDAFKQQLGGERVAPGVFLTFSPKFSAVGLPEPAVEYRGQALALSAPIQVSDQSSINISVDAILEKVKGLQQDNRQLQSALGSAALASQPKELAERIAAADSAGQDPCARGGDATLCGWKQLSSGQLGSAEATLTQAVEQAPAADPRAKGAALSGLGEIYVGQGRIDEAKVALRKAAELGNDGAKKRLQTLALPVAEPARLELRERPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBA1</accession>
    <name>A0A0S2DBA1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">L-alanyl-D-glutamate peptidase</fullName>
            <ecNumber evidence="3">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ply</name>
        <name evidence="4" type="ORF">BV903_10280</name>
        <name evidence="3" type="ORF">GLE_0428</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">B25</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.24.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000022">
        <property type="protein sequence ID" value="OPD64090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0428"/>
    <dbReference type="EnsemblBacteria" id="ALN55786">
        <property type="protein sequence ID" value="ALN55786"/>
        <property type="gene ID" value="GLE_0428"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64090">
        <property type="protein sequence ID" value="OPD64090"/>
        <property type="gene ID" value="BV903_10280"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0428"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.425"/>
    <dbReference type="OMA" id="ISERDAW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039561">
        <property type="entry name" value="Peptidase_M15C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13539">
        <property type="entry name" value="Peptidase_M15_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M15_4" evidence="2">
        <location>
            <begin position="218"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD64090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="297" mass="32882" checksum="E9A34562C8F1AA17" modified="2016-02-17" version="1">MVWLAVTVSFLVFAVVAWLAMFPGARDEAGGRAGRMLQRGSAFIERLRRRASQQTRESGQELRTKSAGYARRVSRSKYFLIAAAVMVIVPVSLILGLRQKVILDGGTDPVPVATSSQIRELLEGENLVPPEPPPPEVFVEAERELAQLSPSARLSIAAPEEIVSADRRWEQIDRDFRQRVLAIYKVMEGRGIKMVLVEGFRSAKRQAELAAAGKATRAGAGQSCHQYGLAVDSAPIRNGKLQWDMNDPWTRDAYHLYGQLAQEAGLEWGGSWRSIKDYVHLEQKDRCRAARRAAGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBJ5</accession>
    <name>A0A0S2DBJ5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0508</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0508"/>
    <dbReference type="EnsemblBacteria" id="ALN55866">
        <property type="protein sequence ID" value="ALN55866"/>
        <property type="gene ID" value="GLE_0508"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0508"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.503"/>
    <dbReference type="OMA" id="PHDERSR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594809" evidence="1">
        <location>
            <begin position="29"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="52"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="409" mass="44502" checksum="EA168790A2DC6CAB" modified="2016-02-17" version="1">MPLLASLLRRPRAAALLAALLLATVLLAAALPAAAARPLARPHALPEPAALDAEVARAMAATGARGLAVAVVDDGRVVQVRAYGERNARGEPLRTDTVMYGASLTKAVFAYTVMQLVDDGRIELDRPLADYFDRPLPDYPADRKYGPYADLAGDERWRKLTARHLLTHSGGFANFAFLEPDRRLRIHFEPGTRYSYSGEGLILLQFALERGLGLDLGREMDERVFAPLGMRDTGMIWQPRFAANLADGWTLDGTAVAHDERSRVRAAGSMDTSIADIARFAAALVRGEGLSPRSRKDLVRAQLPIASASQFPVLQPDLPAAQRRRDLAAGLGVVAFRGPQGAGFIKGGHDDNTGNTLVCIERGRRCVVLLSNDVRAEPAFAHLVAFVLGETGAPYRWEYGSMRFWEPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBJ9</accession>
    <name>A0A0S2DBJ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0314</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945947.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55672">
        <property type="protein sequence ID" value="ALN55672"/>
        <property type="gene ID" value="GLE_0314"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0314"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.311"/>
    <dbReference type="OrthoDB" id="1752426at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="284" mass="30395" checksum="6E6C4AA60D0E2474" modified="2016-02-17" version="1">MSTVDPALARRRERLDAGPPPRPGWRPWLLLAAYAGCWAMFGYGLGDAAHYPVATGYLAPELQPPNQTPALLWMLFVGVFAGMLLGLAADGELGAILGGAGGTAGAFAINLGATALGLWRGAADRWTAPPRLGFFDAGATLPWGAGGWLSWNAQYWAPALLAALAALLAAVALTSRRRQRRRHERIRATLAQGQRTAGTVTETADTGVAVGHRPHIRVVARFSDHLGTGRWVTKIGPFDPARLPRVGDPVQVWFLREAPGDEDRIVVGFGSEEDAGIEERLARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBM9</accession>
    <name>A0A0S2DBM9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0562</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55920">
        <property type="protein sequence ID" value="ALN55920"/>
        <property type="gene ID" value="GLE_0562"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0562"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.556"/>
    <dbReference type="OMA" id="MYPWENA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027365">
        <property type="entry name" value="GNAT_acetyltra_YdfB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12746">
        <property type="entry name" value="GNAT_acetyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="122"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="251" mass="26830" checksum="A430DC75B2AB068B" modified="2016-02-17" version="1">MAAGRRHWYARMSMFSALVETHWQQAFAGDTTRWREPALTVTIDIRAHARFRAILLETGAGARAMLDPALADALVAAVGASLDPVGLRQALAQAGAPLYGADHLFYFPLRDQAGVLAEPPAAHVRALGPDDAAAFAAFESEASEPDRDDAYVALDHDAAFGAFADGRLVCAASMYRWDESRLMDLGVLTLAGHRGRGHARAVVRAIARHALAQGWEPQYRCQLDNAASVALAVAAGLSGYGRWDVAPSSPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC99</accession>
    <name>A0A0S2DC99_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA polymerase III, subunits gamma and tau-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0789</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56147">
        <property type="protein sequence ID" value="ALN56147"/>
        <property type="gene ID" value="GLE_0789"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0789"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.778"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="73" mass="8032" checksum="3532D929F3042BBA" modified="2016-02-17" version="1">MCGQAPPRVEPGRRRARSGRKNPRLFQRFAPPLARARGLIYTEPTHAGRPGCLSAFAQPVPLPAEPPRRSPAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCQ9</accession>
    <name>A0A0S2DCQ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_0942</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946413.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0942"/>
    <dbReference type="EnsemblBacteria" id="ALN56300">
        <property type="protein sequence ID" value="ALN56300"/>
        <property type="gene ID" value="GLE_0942"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0942"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.930"/>
    <dbReference type="OMA" id="RACQAND"/>
    <dbReference type="OrthoDB" id="997498at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025738">
        <property type="entry name" value="BatD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40940">
        <property type="entry name" value="PTHR40940"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13584">
        <property type="entry name" value="BatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594836" evidence="3">
        <location>
            <begin position="24"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="555"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="564"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="578" mass="60589" checksum="5491F2A7363B2BC1" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCS7</accession>
    <name>A0A0S2DCS7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metallo-beta-lactamase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0958</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946423.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0958"/>
    <dbReference type="EnsemblBacteria" id="ALN56316">
        <property type="protein sequence ID" value="ALN56316"/>
        <property type="gene ID" value="GLE_0958"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0958"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.945"/>
    <dbReference type="OMA" id="LYLCHDY"/>
    <dbReference type="OrthoDB" id="1581636at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050313">
        <property type="term" value="F:sulfur dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07724">
        <property type="entry name" value="POD-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044528">
        <property type="entry name" value="POD-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="20"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="299" mass="32178" checksum="EFB8DF9ADAF2DE51" modified="2016-02-17" version="1">MPPAPAAAPHVSAFHHRDTGTWTYLVADPATRAAAIVDPVLDFDPRSGRTGLDSVAPLLERAAADGLRIDWLLETHAHADHLSAAHALRERLRAADGRAPRLAIGRRIGEVRRVFAPLFGLSDEEPAQQPAAFDHLFDDDEGFAVGALPARAIPVPGHTQDSLAYLIGDALFAGDSLFMPDSGTARCDFPGGDAAMLYQSIQRLYLLPEATRVFVCHDYGKDGREPACETTIGAQKQGNLHVRADTDEAGFVALREARDRTLAVPALILPSLQVNLRGGALPEPEANGVRYLKLPLDQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCX8</accession>
    <name>A0A0S2DCX8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Methylenetetrahydrofolate reductase</fullName>
            <ecNumber evidence="10">1.5.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">metF</name>
        <name evidence="12" type="ORF">FE772_05740</name>
        <name evidence="11" type="ORF">GLE_1029</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 10">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:19821"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.5.1.20"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19817"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 10">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 10">Belongs to the methylenetetrahydrofolate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.20" evidence="10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946474.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1029"/>
    <dbReference type="EnsemblBacteria" id="ALN56387">
        <property type="protein sequence ID" value="ALN56387"/>
        <property type="gene ID" value="GLE_1029"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1029"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1017"/>
    <dbReference type="OMA" id="EMHPQAR"/>
    <dbReference type="OrthoDB" id="1425269at2"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004489">
        <property type="term" value="F:methylenetetrahydrofolate reductase (NAD(P)H) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00537">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003171">
        <property type="entry name" value="Mehydrof_redctse-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004620">
        <property type="entry name" value="MTHF_reductase_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02219">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="SSF51730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00676">
        <property type="entry name" value="fadh2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0274">FAD</keyword>
    <keyword evidence="6 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="8 10 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN56387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW25233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="274" mass="30305" checksum="C5E8B30316073AE0" modified="2016-02-17" version="1">MLPISFEFYPPKTDDQRSQLDKTAAKLRGFSPSYVSCTFGAGGSTLSYTPETIRRLRGKHGLDAAPHLSCVGGTRGEIRQLLELYRELGCRRLVTLRGDLPSGMASAGDLRYANELVEFIRAETGDHFHIEVAAYPETHPQARDALSDLENFKRKVRAGADGAITQYFYNPDAYFRFVDDVRAAGIDVPIVPGIMPIANFSQLRRFSDLCGAEIPRWIAQRMQAYGDDADSIREFAADVVARLCSRLIEGGAPGLHFYTLNLAKPTLSVLSRIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD85</accession>
    <name>A0A0S2DD85_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_06120</name>
        <name evidence="2" type="ORF">GLE_1116</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946535.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56474">
        <property type="protein sequence ID" value="ALN56474"/>
        <property type="gene ID" value="GLE_1116"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1116"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1102"/>
    <dbReference type="OMA" id="AFKTDAF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="82" mass="8528" checksum="7A65CD9422E5B40A" modified="2016-02-17" version="1">MSTALTILGCAIGLVGALWLLALAFQEHLGWGLGSLLFVPVLALFAFLHWDRARTPALLNLAGLALAVIGVFMGAAPTREAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDC1</accession>
    <name>A0A0S2DDC1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">HPr family phosphocarrier protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Phosphocarrier protein HPr</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Phosphocarrier protein HPr (Histidine-containing protein)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ptsH</name>
        <name evidence="6" type="ORF">BV903_16350</name>
        <name evidence="7" type="ORF">FE772_06440</name>
        <name evidence="5" type="ORF">GLE_1184</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000043">
        <property type="protein sequence ID" value="OPD62850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946579.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1184"/>
    <dbReference type="EnsemblBacteria" id="ALN56542">
        <property type="protein sequence ID" value="ALN56542"/>
        <property type="gene ID" value="GLE_1184"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62850">
        <property type="protein sequence ID" value="OPD62850"/>
        <property type="gene ID" value="BV903_16350"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1184"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1169"/>
    <dbReference type="OMA" id="SIMAMMM"/>
    <dbReference type="OrthoDB" id="404807at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00367">
        <property type="entry name" value="PTS-HPr_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000032">
        <property type="entry name" value="HPr-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035895">
        <property type="entry name" value="HPr-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001020">
        <property type="entry name" value="PTS_HPr_His_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002114">
        <property type="entry name" value="PTS_HPr_Ser_P_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00381">
        <property type="entry name" value="PTS-HPr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00107">
        <property type="entry name" value="PHOSPHOCPHPR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55594">
        <property type="entry name" value="SSF55594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01003">
        <property type="entry name" value="PTS_HPr_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51350">
        <property type="entry name" value="PTS_HPR_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00369">
        <property type="entry name" value="PTS_HPR_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00589">
        <property type="entry name" value="PTS_HPR_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0598">Phosphotransferase system</keyword>
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    <evidence type="ECO:0000313" key="5">
        <source>
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    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD62850.1"/>
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        <source>
            <dbReference type="EMBL" id="QCW25353.1"/>
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    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
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    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="89" mass="9624" checksum="1F00912722CED314" modified="2016-02-17" version="1">MIERELTVSNRLGLHARATAKLVQVLSAFRSNATLTAKGREVNAKSIMGVMLLAAGQGTHVKLRVDGEDEANAAEAVVALFERRFDEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
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    </evidence>
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</entry>
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        </location>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="50" mass="5624" checksum="C386FFC35235B7D4" modified="2016-02-17" version="1">MTITHSAIDPNVMIGKSRMRPTCQGPGYRSASPRFRAARPRPPRRFLGAR</sequence>
</entry>
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    <accession>A0A0S2DEA9</accession>
    <name>A0A0S2DEA9_LYSEN</name>
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        <submittedName>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
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        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 7">B25</strain>
        </source>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="162" mass="18519" checksum="44A0F36D7230C0B5" modified="2016-02-17" version="1">MPYTPIVATLGYVLSPDGRQVLMVHRNARPDDHQLGKYNGLGGKLEPDEDVLAGMRREIREEAGIECTALQLRGTISWPGFGKRGEDWLGFVFVITAFEGEPYASNPEGTLEWADLDRLHELPMWEGDREFLPLVFDRDPRPFHGVMPYREGRMVSWNFSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DES3</accession>
    <name>A0A0S2DES3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carboxymuconolactone decarboxylase family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Gamma-carboxymuconolactone decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pcaC</name>
        <name evidence="3" type="ORF">BV903_07075</name>
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        <name evidence="2" type="ORF">GLE_1653</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="NZ_MTAY01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1653"/>
    <dbReference type="EnsemblBacteria" id="ALN57010">
        <property type="protein sequence ID" value="ALN57010"/>
        <property type="gene ID" value="GLE_1653"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64646">
        <property type="protein sequence ID" value="OPD64646"/>
        <property type="gene ID" value="BV903_07075"/>
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    <dbReference type="KEGG" id="lez:GLE_1653"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1632"/>
    <dbReference type="OMA" id="LRCDDCV"/>
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    <dbReference type="Proteomes" id="UP000190203">
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    <dbReference type="GO" id="GO:0051920">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
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</entry>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
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    <dbReference type="OrthoDB" id="1070946at2"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="231" mass="24950" checksum="42D29F6DD8AE47D0" modified="2016-02-17" version="1">MPTADLHDSLQRRGFAHWPGALAPEQVAAVAAQPLLAEAADTDAGDRELLREPWCGALAARLRERLAAAGVLAPDAVAVQCTLFRKSALRNWKVTLHQDLSIPVAAAVADPRLGAWSRKQGRPFVQPPAELLQRLLAVRLHLDDCGAGDGPLRVVAGSHRHGRLDAAAAQALRAAEGETECTADRGDLLIMRPLLLHASSKATRPEGRRRVLHFLFGPREPGYSLHWSIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEY1</accession>
    <name>A0A0S2DEY1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Ankyrin repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_21820</name>
        <name evidence="4" type="ORF">FE772_07965</name>
        <name evidence="2" type="ORF">GLE_1520</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="OPD61815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946844.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000072.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1520"/>
    <dbReference type="EnsemblBacteria" id="ALN56877">
        <property type="protein sequence ID" value="ALN56877"/>
        <property type="gene ID" value="GLE_1520"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61815">
        <property type="protein sequence ID" value="OPD61815"/>
        <property type="gene ID" value="BV903_21820"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1520"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1502"/>
    <dbReference type="OMA" id="QWAILNQ"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF12796">
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        <location>
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    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="151"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="225" mass="23800" checksum="7AFC8D2CB4A5CD9D" modified="2016-02-17" version="1">MSEAQPQSLAAQVFADPVAAELADAVAAGDRAAIRRLVERAPAALSARGDKNVTLPEWAVFNQSPEGLDELLALGADPSRPGVDGSTVVHLAAMARDPVYLETLLARGADPNIEHAHTGAAPLAAALMGDREIQFRRLLAAGADPRHVDRMGNTALHVAGKVNQPDLALELLKAGTDPHARNAQNVSFQRYAFMTPPSLLSAKARADREALAAWMRERGIALESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEZ0</accession>
    <name>A0A0S2DEZ0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hypoxanthine phosphoribosyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Hypoxanthine-guanine phosphoribosyltransferase</fullName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">hpt</name>
        <name evidence="3" type="ORF">BV903_13325</name>
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        <name evidence="4" type="ORF">FE772_08890</name>
        <name evidence="2" type="ORF">GLE_1719</name>
    </gene>
    <organism evidence="2 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">C3</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 9" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.2.8" evidence="2 4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000034">
        <property type="protein sequence ID" value="OPD63409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="ROU05443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_RCTY01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1719"/>
    <dbReference type="EnsemblBacteria" id="ALN57074">
        <property type="protein sequence ID" value="ALN57074"/>
        <property type="gene ID" value="GLE_1719"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD63409"/>
        <property type="gene ID" value="BV903_13325"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1719"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1697"/>
    <dbReference type="OMA" id="TMDWMAV"/>
    <dbReference type="OrthoDB" id="1819460at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052657">
        <property type="term" value="F:guanine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004422">
        <property type="term" value="F:hypoxanthine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="1">
        <location>
            <begin position="16"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU05443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="183" mass="20470" checksum="3C2B12EB7D87DD17" modified="2016-02-17" version="1">MSNHDLAAALENADLIFDRRSLEREIARMAVRIRNDYAGARPVYLTVMHGGLPFAAQLAMELGQRGLDLEFDYLHATRYRGATTGADLVWKHRPATPLRGRRVLLADDIVDEGHTLHAIRAWCLEQGAAEVRIAALAVKAHDRCVEGLCADYVGVEVPDRYVFGYGMDFHEQGRNLPAIYALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF07</accession>
    <name>A0A0S2DF07_LYSEN</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="gene ID" value="GLE_1750"/>
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        <property type="gene ID" value="BV903_13440"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD63429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="132" mass="14545" checksum="543071B077E2E510" modified="2016-02-17" version="1">MQVETNDYVELKHEILDGMRSYMEDLAQDGADAGYGAAEIDECERVIDALLAALRNAVGDGERVPSPAQLDRSARAAVEQAVRALNALNARCRYNLIETDQREGLCELVRSALAGIGALRGQDDPTEPWREW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF55</accession>
    <name>A0A0S2DF55_LYSEN</name>
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        <submittedName>
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        </submittedName>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">C3</strain>
        </source>
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    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN57270">
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        <property type="gene ID" value="GLE_1919"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25912.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="181" mass="19845" checksum="04DC4C8B88B54AC9" modified="2016-02-17" version="1">MNAIAQHAGTDTDLGSRILKVNHAGEHGAVNIYAGQIRMARLTAPHLLQELNAFRADEQRHRALFRAELERRGRARCRSYGLCGFGGYALGLITGLFGARAIAATTVAVERVVLRHLAHQLEQLSGRDPAAVAAISAILDEEREHHDTSAGHLHEDRFWSRLLSPVVSASTETVIWLGMKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF87</accession>
    <name>A0A0S2DF87_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">Heme-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_08410</name>
        <name evidence="2" type="ORF">GLE_1618</name>
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        <dbReference type="NCBI Taxonomy" id="69"/>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="ALN56975"/>
        <property type="gene ID" value="GLE_1618"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1618"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
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        <location>
            <begin position="21"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="160" mass="16561" checksum="3FE78C2C7E39EAF4" modified="2016-02-17" version="1">MLRTSLPLAVLLLAAMPSHAATPLKTQLPQRTVLNLAAAERIAAAAAAEARAQGLTVSIAVVDEAGRLMHFQRMDGTPNSSVEVAIGKAVHAADYRRDSGFHQKLLEDGNHVVLALPHSLPIEGGVRLLLDGQTIGGIGVSGAQAAQDGRIAQAGADLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFB6</accession>
    <name>A0A0S2DFB6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
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    <gene>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57271">
        <property type="protein sequence ID" value="ALN57271"/>
        <property type="gene ID" value="GLE_1920"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1920"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1886"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="48" mass="5480" checksum="F8DA977AC47C1F92" modified="2016-02-17" version="1">MQAATSSAKAAFLRPWLRGAVDGASWLHWRGRGSRRCDWGLRMSRCFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFK6</accession>
    <name>A0A0S2DFK6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1748</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57103.1"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
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    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57103.1"/>
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    </evidence>
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        <source>
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    </evidence>
    <sequence length="67" mass="7165" checksum="DBD8BF99695C17C7" modified="2016-02-17" version="1">MNRRVVRTHRPIAPATVPRAASPRGTEPSCPRPTLREPTEFRRDPAHKSHLVTGSPPACCGAATSPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFS3</accession>
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            <authorList>
                <person name="Feng T."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        </location>
    </feature>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
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            <dbReference type="EMBL" id="OPD62259.1"/>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="232" mass="24844" checksum="1FD0E7B28EF2A9D2" modified="2016-02-17" version="1">MKRKAILKSPVWAALAASAALLAGGCGGADSGGRAQAEAAPPRAGQMLDPGETAQRLVKMRAQALGGDQQGLQQNLQELNRDFNRSIKLADPSKRVDRENARIAARGVKGVRSVVWIDGENLFAIVDRNADRSYGTVDAICRQLEPLGDTLGVVVNLQSGAARNGDELEILSRNCQLPPGERAMSQPNRQVDALPPQVRAQHRANADAALRAERAGERAESDRIIEANTPEM</sequence>
</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
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                <person name="Fernandez C."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </evidence>
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        </source>
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    </evidence>
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            <dbReference type="EMBL" id="QCW26060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="312" mass="35495" checksum="C8A845A144B2393A" modified="2016-02-17" version="1">MKPLTALDSLDQATFVADYVQRNRPVVVRELDFDPARWTPAAFRADLGDLPVQVYDALFDLQEVATLADYLDRQFGHAGDYREGVPYVRWYNQLKGVDHAWGDEAFARLALRWRMPAFLPRQGLLVPARPQSDATVDAFPYRGILVSARGARTRMHRDPFCSDAVVAQFHGVKEVAMYHPSRADELAARRQDGSSFGGFLDVRGAELGRLAVEPDYHGFIRPGEVIYIPHGWLHDVIVVEDSISVTWNFVHERGSMEFIDYLMSGSESDSEFEVLRYFYRQSGYEFGSSRDIVKAFNQKFCELQELLEAQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG83</accession>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD63915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="155" mass="16882" checksum="A5B10694E035B2C7" modified="2016-02-17" version="1">MSQNLITLDVSDEQLAAAHEALSQLEAVLSGLVSLSPDDRRRLAKMGPKSETFCRQAVRVLEQNPQVVPPSVDLAGALLDLRTLDRLSPLLDRLQRLAERGDDTELALGADIMAFSLEAYGLLKVAGKNQGLDGLRKEMSARWARGRREPATPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGV6</accession>
    <name>A0A0S2DGV6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AbrB family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">AbrB/MazE/SpoVT family DNA-binding domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AbrB family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_01835</name>
        <name evidence="4" type="ORF">FE772_11535</name>
        <name evidence="2" type="ORF">GLE_2296</name>
    </gene>
    <organism evidence="2 5">
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        <lineage>
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    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000004">
        <property type="protein sequence ID" value="OPD65536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947429.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2296"/>
    <dbReference type="EnsemblBacteria" id="ALN57645">
        <property type="protein sequence ID" value="ALN57645"/>
        <property type="gene ID" value="GLE_2296"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65536">
        <property type="protein sequence ID" value="OPD65536"/>
        <property type="gene ID" value="BV903_01835"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2296"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2261"/>
    <dbReference type="OMA" id="MHTFWSV"/>
    <dbReference type="OrthoDB" id="1942483at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04014">
        <property type="entry name" value="MazE_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00966">
        <property type="entry name" value="SpoVT_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01439">
        <property type="entry name" value="lp_hng_hel_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="1">
        <location>
            <begin position="3"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD65536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="74" mass="7991" checksum="7442B589D1697185" modified="2016-02-17" version="1">MEATVAERGQITLPKAVRDALGLTKGTLLKVELDGSRIILRKSVDDAISKARGKFALDGFDSGEDAARSMRDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH03</accession>
    <name>A0A0S2DH03_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">UDP-glucose 4-epimerase</fullName>
            <ecNumber evidence="5 8">5.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLE_2468</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>UDP-alpha-D-glucose = UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:22168"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="5.1.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.2" evidence="5 8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2468"/>
    <dbReference type="EnsemblBacteria" id="ALN57817">
        <property type="protein sequence ID" value="ALN57817"/>
        <property type="gene ID" value="GLE_2468"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2468"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2430"/>
    <dbReference type="OMA" id="NLGNEDW"/>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05247">
        <property type="entry name" value="UDP_G4E_1_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 8" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="9">
        <location>
            <begin position="26"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN57817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="346" mass="37154" checksum="E526877B8D62DD09" modified="2016-02-17" version="1">MTLSSPRTVDREGFVAAAPRADSPHVLVCGGAGYVGAHAAYALARRGVRVSVLDNLSTGHRQALRWGRWIDADLLDPASLDAAFAEPVDAVMHFCARSLVGESVAEPYDYYLNNVAGSLNLLRAMRAHGVGRLVFSSSAAVFGRPRAPRIDEDHPTAPINPYGASKLMVERILADAARAYGLRSVSLRYFNAAGAASEAGIGESHTPETHLIPNVLRAALGQGAPLRVFGDDYDTADGTCVRDYVHVLDLADAHVRALDWMDANAGAHCFNLGNGTGFSVLEIVRAAQRVTGREIAYEVAPRREGDPAVLVASSAAARERLGWTPRHGAIEEIIDSAWRWHRAPAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH18</accession>
    <name>A0A0S2DH18_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57943">
        <property type="protein sequence ID" value="ALN57943"/>
        <property type="gene ID" value="GLE_2595"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2595"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2555"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="45" mass="5245" checksum="0FF10D853F02B650" modified="2016-02-17" version="1">MSWKRERRSARVGCSVSMRLLPMREHSTERFSHFSTGISSRFGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH48</accession>
    <name>A0A0S2DH48_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha-ketoglutarate-dependent dioxygenase AlkB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_11845</name>
        <name evidence="2" type="ORF">GLE_2366</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947483.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2366"/>
    <dbReference type="EnsemblBacteria" id="ALN57715">
        <property type="protein sequence ID" value="ALN57715"/>
        <property type="gene ID" value="GLE_2366"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2366"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2327"/>
    <dbReference type="OMA" id="THEHGIP"/>
    <dbReference type="OrthoDB" id="1391445at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA dealkylation involved in DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035552">
        <property type="term" value="P:oxidative single-stranded DNA demethylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032854">
        <property type="entry name" value="ALKBH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31212">
        <property type="entry name" value="PTHR31212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="1">
        <location>
            <begin position="93"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="192" mass="21557" checksum="EE01FB01EA83AF8D" modified="2016-02-17" version="1">MHQASLFAAQPQHPILDAEGGVRYLPDVFAPDWCARLFAELWDGAAWNSEQRLMYERLVEVPRRVARYRIGRDRLPPLLETAAGRVREVLAAPFDSIGLNLYRDGRDSVAPHNDKLHDLVPGQPIAVLSLGATRRMTIRAKRKPHASWHIELEPGSLLVMSHASQHHYDHGIPKDPGVTDARISAAFRVRGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH84</accession>
    <name>A0A0S2DH84_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57704">
        <property type="protein sequence ID" value="ALN57704"/>
        <property type="gene ID" value="GLE_2355"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2355"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="49" mass="4819" checksum="13AE52CF813AC583" modified="2016-02-17" version="1">MEGVERGVGGVGVWGHGERPAGGRCGDGVDMGAIVAPASLRPGGRGRCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHC8</accession>
    <name>A0A0S2DHC8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF664 domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">DinB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_12600</name>
        <name evidence="2" type="ORF">GLE_2507</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DinB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2507"/>
    <dbReference type="EnsemblBacteria" id="ALN57856">
        <property type="protein sequence ID" value="ALN57856"/>
        <property type="gene ID" value="GLE_2507"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2507"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2470"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007837">
        <property type="entry name" value="DinB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05163">
        <property type="entry name" value="DinB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="164" mass="18297" checksum="69717954417AA9F7" modified="2016-02-17" version="1">MRADIHSVLKTWERENETTLEVFSRVPEGRNEQTVVPDKGWTLGGLVWHICISERWFCAEVMGARPAGDNEVPADEMPATVAEMAAAFQRSHAALMQAVAEQGEDWVDEAVDFYGNPWTRMELLNLMLRHEAHHRGQLSILMMVAGGQPPTIYGAPGINLEDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHL3</accession>
    <name>A0A0S2DHL3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Hemolysin III family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_12895</name>
        <name evidence="7" type="ORF">GLE_2569</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0073 (Hly-III) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57918">
        <property type="protein sequence ID" value="ALN57918"/>
        <property type="gene ID" value="GLE_2569"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2569"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2528"/>
    <dbReference type="OMA" id="LIPMAHA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019835">
        <property type="term" value="P:cytolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004254">
        <property type="entry name" value="AdipoR/HlyIII-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005744">
        <property type="entry name" value="Hy-lIII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855">
        <property type="entry name" value="PTHR20855"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03006">
        <property type="entry name" value="HlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01065">
        <property type="entry name" value="hlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW26429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="241" mass="25703" checksum="E7705E60C2A67C62" modified="2016-02-17" version="1">MNQETRYGLTSAAWNPRPSRRRSSWLRSIPREERANALTHAAGALAFAVLGAWLVDASLGSGSFALAASVCVFVAALLAMYVASALYHGSADAARKPFLRALDHCSIYLLIAGTYTPFAMALGGGWGALLLAIVWPAAAIGIALKLRAAIGRRWLSTAIYVAMGWVVVIAAHPFLQHFARPTLLWLAAGGLAYTAGTPFYLMSRRRPALHAWWHGFVIAGSAFHFIAVATLVLGATNATQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHS5</accession>
    <name>A0A0S2DHS5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type VI secretion protein, VC_A0114 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Type VI secretion system baseplate subunit TssK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">tssK</name>
        <name evidence="2" type="ORF">FE772_12970</name>
        <name evidence="1" type="ORF">GLE_2584</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947656.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2584"/>
    <dbReference type="EnsemblBacteria" id="ALN57933">
        <property type="protein sequence ID" value="ALN57933"/>
        <property type="gene ID" value="GLE_2584"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2584"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2543"/>
    <dbReference type="OMA" id="YTYFELD"/>
    <dbReference type="OrthoDB" id="496911at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010263">
        <property type="entry name" value="T6SS_TssK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35566">
        <property type="entry name" value="PTHR35566"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05936">
        <property type="entry name" value="T6SS_VasE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03353">
        <property type="entry name" value="VI_chp_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="445" mass="49007" checksum="8393C99BF5B47CAF" modified="2016-02-17" version="1">MIDSNKVIWSEGLFLRPQHMQQQERYLERFVELRAGALRPHAWGFALLELETELLAIGKLAIRRARGCFPDGTPFSIPDRDPAPPPLDVGMDCRDQIVSLSLPLRSAAQPDSAWPDESAPRLTRYRVGETEIGDASGSVAGSVLIEVGSMQSRLRLQSEPKEGLVEIPLARVIECRPDRRVILDDAFVPTVCRIEGAGGLVTLLSELLGLLHQRGQALAERVAGGDRVGVADIADLLMLQTINRYQPLVAHWAHSPLEHPEGLYRLLIEMAGELATFTRASKRGPSFPAYRHEALRESFEPVVLALRESLSAVLEQSAIAVPLQQRKYGVWVGVLADPGLLDAASFVLAVKADVRGEELRKRLPSESKIGPVEKIRDLVNLQLPGIALSSMAIAPRQVPYHAGRQYFELDRHSPLWKALRTSGGMALHFGGGFPGIELELWAVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHV3</accession>
    <name>A0A0S2DHV3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ArsR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Metalloregulator ArsR/SmtB family transcription factor</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_25190</name>
        <name evidence="4" type="ORF">FE772_13490</name>
        <name evidence="2" type="ORF">GLE_2693</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000107">
        <property type="protein sequence ID" value="OPD61144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947741.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000107.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2693"/>
    <dbReference type="EnsemblBacteria" id="ALN58041">
        <property type="protein sequence ID" value="ALN58041"/>
        <property type="gene ID" value="GLE_2693"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61144">
        <property type="protein sequence ID" value="OPD61144"/>
        <property type="gene ID" value="BV903_25190"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2693"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2652"/>
    <dbReference type="OMA" id="SWAREAC"/>
    <dbReference type="OrthoDB" id="1515497at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="326" mass="35754" checksum="7404DF67162467BE" modified="2016-02-17" version="1">MDLEGWSARLKVFADATRVRLLALLEREELTVAELSAITRLAQPRVSTHLSKLKEAGLVRDRRAGVSAYYRFDEGALDNAQRALWQTLSTGSDDPLLRQDAERVPAVLAMRASDQNWADSVAGDMERHYSPGRTWEALARSALPLLQPGDVLDIASGDGVLAELLAPHSHRYICLDASTKVVAAASERLRKLRNVEVREGDMHALPFAAETFDLVVLMHALTYAEQPAQAVAEAARVLRPGGRVLLTSLARHEHRGAVEAFGHVNLGFTEKDLQKFAAKAGFDIVSCETVTRERRPPHFEVIALMARKPLPEPAAASPAARKPAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI55</accession>
    <name>A0A0S2DI55_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha-2-macroglobulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FE772_13710</name>
        <name evidence="6" type="ORF">GLE_2740</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Protects the bacterial cell from host peptidases.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947779.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2740"/>
    <dbReference type="EnsemblBacteria" id="ALN58088">
        <property type="protein sequence ID" value="ALN58088"/>
        <property type="gene ID" value="GLE_2740"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2740"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2698"/>
    <dbReference type="OMA" id="YGCAEQR"/>
    <dbReference type="OrthoDB" id="231654at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004866">
        <property type="term" value="F:endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026284">
        <property type="entry name" value="A2-macglob_dom_prot_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011625">
        <property type="entry name" value="A2M_N_BRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040639">
        <property type="entry name" value="A2MG_MG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021868">
        <property type="entry name" value="Alpha_2_Macroglob_MG3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041203">
        <property type="entry name" value="Bact_A2M_MG5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041462">
        <property type="entry name" value="Bact_A2M_MG6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041246">
        <property type="entry name" value="Bact_MG10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001599">
        <property type="entry name" value="Macroglobln_a2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002890">
        <property type="entry name" value="MG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00207">
        <property type="entry name" value="A2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07703">
        <property type="entry name" value="A2M_BRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17970">
        <property type="entry name" value="bMG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17973">
        <property type="entry name" value="bMG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11974">
        <property type="entry name" value="bMG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17972">
        <property type="entry name" value="bMG5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17962">
        <property type="entry name" value="bMG6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01835">
        <property type="entry name" value="MG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038980">
        <property type="entry name" value="A2M_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01360">
        <property type="entry name" value="A2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01359">
        <property type="entry name" value="A2M_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="A2M_N_2" evidence="4">
        <location>
            <begin position="739"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="domain" description="A2M" evidence="5">
        <location>
            <begin position="946"/>
            <end position="1035"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR038980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW26562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="1633" mass="177341" checksum="9C9E48E45EC2855E" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIE6</accession>
    <name>A0A0S2DIE6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10">Phosphoenolpyruvate synthase</fullName>
            <shortName evidence="10">PEP synthase</shortName>
            <ecNumber evidence="6 10">2.7.9.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">Pyruvate, water dikinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ppsA</name>
        <name evidence="15" type="ORF">FE772_14380</name>
        <name evidence="14" type="ORF">GLE_2877</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">C3</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 10">Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + H2O + pyruvate = AMP + 2 H(+) + phosphate + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:11364"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.9.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 10">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 10">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.7.9.2" evidence="6 10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947878.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2877"/>
    <dbReference type="EnsemblBacteria" id="ALN58225">
        <property type="protein sequence ID" value="ALN58225"/>
        <property type="gene ID" value="GLE_2877"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2877"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2839"/>
    <dbReference type="OMA" id="LETWFFL"/>
    <dbReference type="OrthoDB" id="997616at2"/>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008986">
        <property type="term" value="F:pyruvate, water dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006090">
        <property type="term" value="P:pyruvate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006319">
        <property type="entry name" value="PEP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018274">
        <property type="entry name" value="PEP_util_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43030">
        <property type="entry name" value="PTHR43030"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000854">
        <property type="entry name" value="PEP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01418">
        <property type="entry name" value="PEP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00370">
        <property type="entry name" value="PEP_ENZYMES_PHOS_SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPDK_N" evidence="12">
        <location>
            <begin position="18"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="11">
        <location>
            <begin position="386"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers_C" evidence="13">
        <location>
            <begin position="484"/>
            <end position="790"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00021623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN58225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW26662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="795" mass="86415" checksum="7F4C9A44917C1763" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIF7</accession>
    <name>A0A0S2DIF7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TatD related DNase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3058</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3058"/>
    <dbReference type="EnsemblBacteria" id="ALN58405">
        <property type="protein sequence ID" value="ALN58405"/>
        <property type="gene ID" value="GLE_3058"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3058"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3018"/>
    <dbReference type="OMA" id="CHLDAGE"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018228">
        <property type="entry name" value="DNase_TatD-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005902">
        <property type="entry name" value="DNase_TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01137">
        <property type="entry name" value="TATD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01090">
        <property type="entry name" value="TATD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="258" mass="28204" checksum="EF13D5310C2637A8" modified="2016-02-17" version="1">MPSNGLIDSHCHLDAPEFDPDRAEVVARARAAGVAAQVVPAIDAAGWPKLREVCAATPGLHPAYGLHPMFLDSHRPGHLPLLGEWLQRERPCAVGECGLDYYIEGLDRETQSRYFDGQLELAREFDLPVIVHARHAVDATLAAIRRVGGLRGVVHSYSGSEEQAQQLWKLGFLLGLGGPVTYERAQRLRRIAATMPLEFLLLETDAPDQPDAEIRGQRNEPARLAGICGTIARLRGVPAEEVARATSDNARRLFGLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIP0</accession>
    <name>A0A0S2DIP0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Biopolymer transporter ExbB</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="11">MotA/TolQ/ExbB proton channel family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Transporter, MotA/TolQ/ExbB proton channel family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BV903_14490</name>
        <name evidence="11" type="ORF">FE772_15175</name>
        <name evidence="9" type="ORF">GLE_3035</name>
    </gene>
    <organism evidence="9 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">C3</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the exbB/tolQ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000037">
        <property type="protein sequence ID" value="OPD63193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947995.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000037.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3035"/>
    <dbReference type="EnsemblBacteria" id="ALN58382">
        <property type="protein sequence ID" value="ALN58382"/>
        <property type="gene ID" value="GLE_3035"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63193">
        <property type="protein sequence ID" value="OPD63193"/>
        <property type="gene ID" value="BV903_14490"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3035"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2995"/>
    <dbReference type="OMA" id="AYIGYNH"/>
    <dbReference type="OrthoDB" id="1796180at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="8">
        <location>
            <begin position="68"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN58382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD63193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW26784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="219" mass="23561" checksum="F60ED3A121E6E332" modified="2016-02-17" version="1">MLELVKAGGWPMIPLLILSALALAIIIERLWTLRRRAVLPPNLGQEVRAWAAGGKLDPAHIESLRATAPLGALLAAALDVRGRPREEIRERIEDVGRHLVHRMERYLNTLGTIAAAGPLLGLFGTVVGMIQMFLVINDQGIGDVNQLAGGIGKALVCTATGMIVAIPALIAHRWFRGRVSEYIVAMEHEAIALVDVLQQHPGEGRASEPRPVRLAGGQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIS3</accession>
    <name>A0A0S2DIS3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Potassium-transporting ATPase ATP-binding subunit</fullName>
            <ecNumber evidence="12">7.2.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">ATP phosphohydrolase [potassium-transporting] B chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Potassium-binding and translocating subunit B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Potassium-translocating ATPase B chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12 13" type="primary">kdpB</name>
        <name evidence="14" type="ORF">FE772_15865</name>
        <name evidence="13" type="ORF">GLE_3193</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">C3</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O + K(+)(out) = ADP + H(+) + K(+)(in) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16777"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">The system is composed of three essential subunits: KdpA, KdpB and KdpC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell membrane</location>
            <topology evidence="12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.6" evidence="12"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="entry name" value="ATPASE_E1_E2"/>
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    </dbReference>
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    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0547">Nucleotide-binding</keyword>
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    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 12" id="KW-0813">Transport</keyword>
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            <end position="64"/>
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            <end position="278"/>
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            <end position="617"/>
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    <feature type="transmembrane region" description="Helical" evidence="12">
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            <end position="643"/>
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            <begin position="663"/>
            <end position="686"/>
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        <location>
            <position position="348"/>
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        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:30616"/>
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        <location>
            <position position="352"/>
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            <end position="385"/>
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            <position position="402"/>
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            <name>ATP</name>
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        <location>
            <position position="525"/>
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            <name>Mg(2+)</name>
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        <source>
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        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="687" mass="71131" checksum="438027DFC8F88142" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
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        </alternativeName>
        <alternativeName>
            <fullName evidence="13">tRNA [GM37] methyltransferase</fullName>
        </alternativeName>
    </protein>
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        <name evidence="19" type="ORF">FE772_16115</name>
        <name evidence="18" type="ORF">GLE_3253</name>
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    <organism evidence="18 20">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
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    <reference evidence="18 20" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 20">C3</strain>
        </source>
    </reference>
    <reference evidence="19 21" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 21">YC36</strain>
        </source>
    </reference>
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        <text evidence="2 13 15">Specifically methylates guanosine-37 in various tRNAs.</text>
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    <comment type="catalytic activity">
        <reaction evidence="1 13 15">
            <text>guanosine(37) in tRNA + S-adenosyl-L-methionine = H(+) + N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine</text>
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            <dbReference type="Rhea" id="RHEA-COMP:10145"/>
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            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.228"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5 13 15">Homodimer.</text>
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    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 13 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
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        <property type="protein sequence ID" value="QCW26933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="GLE_3253"/>
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        <property type="project" value="UniProtKB-EC"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Alpha/beta_knot_MTases"/>
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        <property type="entry name" value="tRNA_m1G_MeTrfase_bac"/>
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        <property type="entry name" value="tRNA_m1G_MeTrfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016009">
        <property type="entry name" value="tRNA_MeTrfase_TRMD/TRM10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46417">
        <property type="entry name" value="PTHR46417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01746">
        <property type="entry name" value="tRNA_m1G_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000386">
        <property type="entry name" value="tRNA_mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="trmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="9 13 15" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 13 14" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="10 13 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 13 15" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA_m1G_MT" evidence="17">
        <location>
            <begin position="23"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="13 14">
        <location>
            <begin position="133"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="247"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000386-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF01746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ALN58599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="QCW26933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="279" mass="29785" checksum="C8E7DC909610606D" modified="2016-02-17" version="1">MRIDVISLFPEFVAQCAAFGVVGRAGERGLLSMHGWNPRDYAEGNYRRVDERPFGGGPGMVMLIDPLRAAIRAARAADPAPARVVYLSPQGARLDQAKVRELAGHARLILLCGRYEGVDERLIRAEVDEELSIGDYVLSGGELAAAVVVDAVARLQDGALGDAESAVQDSFEDGLLDCPHYTRPVEHELGAVPEVLMSGNHARIAQWRRQQSLGRTWQRRPDLFDEAALSKADRKLLAAYRAELATAGEGAETGSRAASEAVSVPAADGSATGGAARGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIT1</accession>
    <name>A0A0S2DIT1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione S-transferase</fullName>
            <ecNumber evidence="4">2.5.1.18</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Glutathione S-transferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_15260</name>
        <name evidence="4" type="ORF">GLE_3053</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057950153.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3053"/>
    <dbReference type="EnsemblBacteria" id="ALN58400">
        <property type="protein sequence ID" value="ALN58400"/>
        <property type="gene ID" value="GLE_3053"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3053"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3013"/>
    <dbReference type="OMA" id="TCLWESN"/>
    <dbReference type="OrthoDB" id="1752966at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="84"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="216" mass="24134" checksum="3734B2FB04BC5424" modified="2016-02-17" version="1">MITVHGFSPSGNCHKLRLLLEQLGERYRWVEVDSSRGETRTAQFLALNPNGKVPVVDFGDGRTLTESNAILYYLADGSEFLPADLWQRAQALSWMNFEQYSHEPSIAVARFIAGWTPLDSPRRADLPALRERGHQALAVMERHLQERAWFTGERYGIADIALFAYTDVAAHGGIGLDGYPAIVSWLARVRATPRFVALPEPDAQAAQRIAESNRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIY8</accession>
    <name>A0A0S2DIY8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosomal protein S12 methylthiotransferase RimO</fullName>
            <shortName evidence="7">S12 MTTase</shortName>
            <shortName evidence="7">S12 methylthiotransferase</shortName>
            <ecNumber evidence="7">2.8.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Ribosome maturation factor RimO</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">yliG</name>
        <name evidence="7 12" type="synonym">rimO</name>
        <name evidence="12" type="ORF">FE772_15605</name>
        <name evidence="11" type="ORF">GLE_3137</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[sulfur carrier]-SH + AH2 + L-aspartate(89)-[ribosomal protein uS12]-hydrogen + 2 S-adenosyl-L-methionine = 3-methylsulfanyl-L-aspartate(89)-[ribosomal protein uS12]-hydrogen + 5'-deoxyadenosine + [sulfur carrier]-H + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:37087"/>
            <dbReference type="Rhea" id="RHEA-COMP:10460"/>
            <dbReference type="Rhea" id="RHEA-COMP:10461"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:29961"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:73599"/>
            <dbReference type="EC" id="2.8.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="7">Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the methylthiotransferase family. RimO subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.4.4" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948070.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3137"/>
    <dbReference type="EnsemblBacteria" id="ALN58484">
        <property type="protein sequence ID" value="ALN58484"/>
        <property type="gene ID" value="GLE_3137"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3137"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3095"/>
    <dbReference type="OMA" id="HYAYPTG"/>
    <dbReference type="OrthoDB" id="397139at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103039">
        <property type="term" value="F:protein methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018339">
        <property type="term" value="P:peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01865">
        <property type="entry name" value="MTTase_RimO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005840">
        <property type="entry name" value="Ribosomal_S12_MeSTrfase_RimO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041582">
        <property type="entry name" value="RimO_TRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43837">
        <property type="entry name" value="PTHR43837"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18693">
        <property type="entry name" value="TRAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01061">
        <property type="entry name" value="methylthiotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00274">
        <property type="entry name" value="ribosomal_protein_S12_methylth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00089">
        <property type="entry name" value="TIGR00089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01125">
        <property type="entry name" value="TIGR01125"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="12" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 7 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="9">
        <location>
            <begin position="9"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="10">
        <location>
            <begin position="140"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="8">
        <location>
            <begin position="386"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN58484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW26859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="456" mass="50009" checksum="FF831A8D8DA9DD1A" modified="2016-02-17" version="1">MSASAPANPKVGFVSLGCPKALVDSERILTQLRVEGYDIVQSYDDADVVVVNTCGFIDSAVTESLDAIGEAIAENGKVIVTGCLGKRSELIREAHPDVLSISGPQDYGSVMSAVHSALPPRHDPFLDLVPRRDDGIGVKLTPKHYAYLKISEGCNHRCSFCIIPSMRGDLVSRPVDDVLREAEKLAMGGVKELLVISQDTSAYGVDVKYAERQWRGKSYQTRMKALCEGLSELGIWTRLHYVYPYPHVDDIIALMAENGANGMPKLLPYLDIPFQHASPRVLKLMKRPGAVDKTLERIQRWRSIAPDIAIRSTFIVGFPGETDAEFEELLDFLDEAQLDRVGAFAYSPVDGAKANDLPDPVPEELKQERLARFMERQAEISAAKLEAKVGSRQRCLVDAIDGELAIARSMADAPEIDGLVQIQNGESAGLRVGQFVDVEIMGSDEHDLFGEAVEND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ93</accession>
    <name>A0A0S2DJ93_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Abortive infection protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">CPBP family intramembrane metalloprotease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_16145</name>
        <name evidence="2" type="ORF">GLE_3260</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948159.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58606">
        <property type="protein sequence ID" value="ALN58606"/>
        <property type="gene ID" value="GLE_3260"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3260"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3213"/>
    <dbReference type="OMA" id="GYHLYQG"/>
    <dbReference type="OrthoDB" id="1623593at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="220" mass="23847" checksum="24E257FC155659DB" modified="2016-02-17" version="1">MVNWIKSLSERSEFVGVLTLAFGWSIYQSLSMALSPQPLTAVFDNASLSGLMGTQLATLAIIGAFLRLRGWTWARLGPAPGWRDLPRGVALAAATLIGFWLFHAVAALIGLLPIDADDSVRVASDLDWRLMLAASAVNGFFEEALVCGYLVSALRERPSMWTAIHLSTAIRASYHLYQGEAGAVMVPMGLAFAWLYSVTGRLWPLVVAHIALDALALFAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJD0</accession>
    <name>A0A0S2DJD0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetylmuramoyl-L-alanine amidase</fullName>
            <ecNumber evidence="2">3.5.1.28</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_3167</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.</text>
            <dbReference type="EC" id="3.5.1.28"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.5.1.28" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3167"/>
    <dbReference type="EnsemblBacteria" id="ALN58513">
        <property type="protein sequence ID" value="ALN58513"/>
        <property type="gene ID" value="GLE_3167"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3167"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3123"/>
    <dbReference type="OMA" id="PYRLIID"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02696">
        <property type="entry name" value="MurNAc-LAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021731">
        <property type="entry name" value="AMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002508">
        <property type="entry name" value="MurNAc-LAA_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01520">
        <property type="entry name" value="Amidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11741">
        <property type="entry name" value="AMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00646">
        <property type="entry name" value="Ami_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="MurNAc-LAA" evidence="5">
        <location>
            <begin position="403"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="290"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="591" mass="59582" checksum="2A29355F93CC40A9" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJI3</accession>
    <name>A0A0S2DJI3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ATPase family associated with various cellular activities (AAA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_3239</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948146.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3239"/>
    <dbReference type="EnsemblBacteria" id="ALN58585">
        <property type="protein sequence ID" value="ALN58585"/>
        <property type="gene ID" value="GLE_3239"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3239"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3192"/>
    <dbReference type="OMA" id="FIFETEP"/>
    <dbReference type="OrthoDB" id="44062at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006415">
        <property type="term" value="P:translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="4">
        <location>
            <begin position="292"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="4">
        <location>
            <begin position="564"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="domain" description="ClpB_D2-small" evidence="5">
        <location>
            <begin position="733"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="31"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1071"/>
            <end position="1096"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1130" mass="124871" checksum="9E34FFE1B30A9584" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJP0</accession>
    <name>A0A0S2DJP0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_17280</name>
        <name evidence="3" type="ORF">GLE_3510</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948343.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58855">
        <property type="protein sequence ID" value="ALN58855"/>
        <property type="gene ID" value="GLE_3510"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3510"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3454"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242316" evidence="2">
        <location>
            <begin position="33"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="153" mass="16642" checksum="8548232AC4FEAF42" modified="2016-02-17" version="1">MKSDKNVPRRFAPALAAAAIAATLAATGAAFAQAHDEAFFKRDIAYFHERSAISVHARLLGAQAVADHHGSDGRLGYRTFRVRARALETFKGDPPGEFDFEVTQEQPSQPPDGGDYILNLSRTPEGRLYPTDDSVGWIRASPGLLAHARGLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJT9</accession>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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        <lineage>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58810">
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    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="67" mass="7466" checksum="E990C72E56426967" modified="2016-02-17" version="1">MLRDGSCRAFCCKEILDYLQKYGATEKIRRLLLSGFISAAFPKAAYAMKPYRFPLGGISITPHPPGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKG5</accession>
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    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">GLE_3651</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58995">
        <property type="protein sequence ID" value="ALN58995"/>
        <property type="gene ID" value="GLE_3651"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3651"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3595"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="68" mass="6725" checksum="058360DEB289C1A0" modified="2016-02-17" version="1">MTSHESNPPTRSRTRDGSQTGRIRRGSANAVGAGPASGSADGNAAAHADMPGDPTADLAIAGPAARTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKJ9</accession>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_18350</name>
        <name evidence="3" type="ORF">GLE_3726</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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        </lineage>
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    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="ALN59070"/>
        <property type="gene ID" value="GLE_3726"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3726"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3671"/>
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    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242680" evidence="2">
        <location>
            <begin position="23"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="1270" mass="142067" checksum="16A66D84ACFF2466" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKR8</accession>
    <name>A0A0S2DKR8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 9">50S ribosomal protein L23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">rplW</name>
        <name evidence="11" type="ORF">BV903_23025</name>
        <name evidence="13" type="ORF">D9T17_09440</name>
        <name evidence="12" type="ORF">FE772_18640</name>
        <name evidence="10" type="ORF">GLE_3788</name>
    </gene>
    <organism evidence="10 14">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 14">C3</strain>
        </source>
    </reference>
    <reference evidence="11 15" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 15">B25</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">OH11</strain>
        </source>
    </reference>
    <reference evidence="12 17" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000077">
        <property type="protein sequence ID" value="OPD61615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="ROU07184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_RCTY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3788"/>
    <dbReference type="EnsemblBacteria" id="ALN59132">
        <property type="protein sequence ID" value="ALN59132"/>
        <property type="gene ID" value="GLE_3788"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61615">
        <property type="protein sequence ID" value="OPD61615"/>
        <property type="gene ID" value="BV903_23025"/>
    </dbReference>
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    <dbReference type="OMA" id="FEVDHRA"/>
    <dbReference type="OrthoDB" id="1978865at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01369_B">
        <property type="entry name" value="Ribosomal_L23_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_L23/L15e_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001014">
        <property type="entry name" value="Ribosomal_L23/L25_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_L25/23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11620">
        <property type="entry name" value="PTHR11620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="SSF54189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00050">
        <property type="entry name" value="RIBOSOMAL_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7 9" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OPD61615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW27359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROU07184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="98" mass="11047" checksum="B33989A362C719F5" modified="2016-02-17" version="1">MNDAKLYSIIRAPRVSEKTARLQEVSNQYVFEVSNEATKGDIKVAVEKLFDVKVEAVNVVNVKGKNKAFRNRMGRRGDWRKAYVTLAEGQSIDVMAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKZ1</accession>
    <name>A0A0S2DKZ1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Linear gramicidin synthetase subunit D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_3997</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3997"/>
    <dbReference type="EnsemblBacteria" id="ALN59339">
        <property type="protein sequence ID" value="ALN59339"/>
        <property type="gene ID" value="GLE_3997"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3997"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3933"/>
    <dbReference type="OMA" id="HERIFAK"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd05235">
        <property type="entry name" value="SDR_e1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="Far_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010080">
        <property type="entry name" value="Thioester_reductase-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01746">
        <property type="entry name" value="Thioester-redct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="1424"/>
            <end position="1501"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="3">
        <location>
            <position position="1461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1908" mass="208022" checksum="38C34B4104F30DFC" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL09</accession>
    <name>A0A0S2DL09_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">30S ribosomal protein S14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 7" type="primary">rpsN</name>
        <name evidence="7" type="ORF">GLE_3777</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the universal ribosomal protein uS14 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3777"/>
    <dbReference type="EnsemblBacteria" id="ALN59121">
        <property type="protein sequence ID" value="ALN59121"/>
        <property type="gene ID" value="GLE_3777"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3777"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3721"/>
    <dbReference type="OMA" id="FGLCRNQ"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00537">
        <property type="entry name" value="Ribosomal_S14_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_S14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023036">
        <property type="entry name" value="Ribosomal_S14_bac/plastid"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19836">
        <property type="entry name" value="PTHR19836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="96" mass="10880" checksum="0C665487615A6474" modified="2016-02-17" version="1">MVNRDLKRAKLAKKFAAKRDALKKIISSDASSYEDKMDAVVKLQKLPRDSSPSRQRNRCALTGRSRGVYQKFGLGRNKLREATMRGDVPGLRKASW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL12</accession>
    <name>A0A0S2DL12_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_17765</name>
        <name evidence="7" type="ORF">GLE_3608</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell inner membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948414.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3608"/>
    <dbReference type="EnsemblBacteria" id="ALN58952">
        <property type="protein sequence ID" value="ALN58952"/>
        <property type="gene ID" value="GLE_3608"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3608"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3552"/>
    <dbReference type="OMA" id="STWYLVP"/>
    <dbReference type="OrthoDB" id="1552415at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00164">
        <property type="entry name" value="ABC2TRNSPORT"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW27202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="366" mass="39837" checksum="4E2CFC15E643B4D1" modified="2016-02-17" version="1">MKLRRLWAIVLKEVRQLRRDRITLAMIVMIPVGQLVLFGYAINLNPRGLTAAVADQAGTAASRALVMDMIATGVIRNVARADTPQQLVGMLRRGEISVGIAVPPDFERRRADGREVLQVMVDGSDTVVQSAAAQLAQTPVDSSAAAPRRIGPSTGSIGVVAFYNPQRRSPVNIVPGLIGVILTMTMVMFTAVAIVRERERGNMELLITTPVSRTELMVGKVLPYALIGLLQTSVVLLLGLWLFEVPVKGSVLDVYVAAVLLILANLALGLLISTKAASQFQAMQMTVFILLPSILLSGFMFPYAGMPAPAQWLAEILPMTHFLRLIRGVMLRGAGLLELWRDVAYLLGFIAVMMSLAVARFRKRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL70</accession>
    <name>A0A0S2DL70_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3842</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59185">
        <property type="protein sequence ID" value="ALN59185"/>
        <property type="gene ID" value="GLE_3842"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3842"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3782"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046116">
        <property type="entry name" value="DUF6053"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19523">
        <property type="entry name" value="DUF6053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="274" mass="29671" checksum="A066D514D30ADC5A" modified="2016-02-17" version="1">MGGTSVPMLSAQVAASGYEGIGAEAPPTTASTTNADRSFDPAAQIFGFCGRDFSPDAFRSDRCDRIQKRSGLKPLPQQQAPQTPTARSIPQRRSSASVGGTSVPTPFAQTSTLQPETTTSKPRRAYRPAEKRAIATSPPRSSGIPCASAHSEFARVLNFDFPFRPPISSATNLRRMRDAMHGCDVEPADLRLVVRDEGDSQSRRGHFDELRRHAQRHAGRALRRNTAIATTKRFKGMHSVAQAAVHASLPYTHAVGGSMRQRPPHSLEHPVPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL89</accession>
    <name>A0A0S2DL89_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA threonylcarbamoyladenosine biosynthesis protein TsaB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_3968</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KAE1 / TsaD family. TsaB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948683.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3968"/>
    <dbReference type="EnsemblBacteria" id="ALN59310">
        <property type="protein sequence ID" value="ALN59310"/>
        <property type="gene ID" value="GLE_3968"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3968"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3905"/>
    <dbReference type="OMA" id="DEVYWGC"/>
    <dbReference type="OrthoDB" id="1826274at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022496">
        <property type="entry name" value="T6A_TsaB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF11">
        <property type="entry name" value="PTHR11735:SF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03725">
        <property type="entry name" value="T6A_YeaZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TsaD" evidence="4">
        <location>
            <begin position="28"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00032446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="242" mass="25129" checksum="08D7790B178304CF" modified="2016-02-17" version="1">MKLLAFETSTEACSVALWLDGEVRERFELAPRRHAELSLPWAEQLLAEAGVKRRELDAVALGRGPGAFTGVRLAIALAQGVALALDVPAIPVSTLAVLALRAQPLAGGAGPQRVLSAIDARMGEVYTAAFELRGGEPFALDREAVLAPDAAQLPGDGAPADGWLGVGTGFAAADGALRQRLGARFAAIDAEALPHAADLARLAAAAYARGESIAPERIEPAYLRNNVALTIAEQAALRARSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLA3</accession>
    <name>A0A0S2DLA3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Universal stress protein family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">uspA</name>
        <name evidence="3" type="ORF">GLE_4009</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948711.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59351">
        <property type="protein sequence ID" value="ALN59351"/>
        <property type="gene ID" value="GLE_4009"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4009"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3946"/>
    <dbReference type="OMA" id="HATFLYR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="2"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="140" mass="14920" checksum="B82B9145DA7D9D49" modified="2016-02-17" version="1">MKILVAVDGSDNALRAVRYAAKISAQFDTPPPLLLLYADPPLMRSVAVSLGAKEVERYHAENARHALSKARAALKRAKVEFNERSAVGDPAAIIAKFARSEQCDMAVMGSHGRSALKSLLLGSVTSKVITAGVLPVLVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLB1</accession>
    <name>A0A0S2DLB1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3938</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948660.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59280">
        <property type="protein sequence ID" value="ALN59280"/>
        <property type="gene ID" value="GLE_3938"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3938"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3875"/>
    <dbReference type="OrthoDB" id="33939at135614"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="222" mass="24503" checksum="C62E30056B610FA9" modified="2016-02-17" version="1">MSVPHSTAPPSPIPLSLHALLAEFADHGRLLSTASFGLDPQWDLDAALAHGWQRSSLQPGPAQQLERDARLPHRGGWQALTLKPFYLRGAYLAASLAPWPRTLPLATVLRWRARRRPALRIEWFEFGGADQGAVLLGGRVGVHFLRRGRRYFVESVESVEAGAAAAADDPDLPGGLDAARWLRRLMAPCDGLARWRALAAQDRYPRAAAQALREIARHLPQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLD6</accession>
    <name>A0A0S2DLD6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_20385</name>
        <name evidence="2" type="ORF">GLE_4157</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59499">
        <property type="protein sequence ID" value="ALN59499"/>
        <property type="gene ID" value="GLE_4157"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4157"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4099"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242186" evidence="1">
        <location>
            <begin position="35"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="269" mass="28294" checksum="2CBC4126BA9F9F50" modified="2016-02-17" version="1">MSAAGDARLRRLRLSACASLAIVCGSFLAGAAFAACKPADAALAGQYASGAPTPLSLRLDADGRFRIYDLPPPLADIAGCWQREGARVVFAPGADGDKDGIERVLPDPLTQADLDKVRGDGIQTLEQAVDAGLLPPARWWAHQPRKPDEPLRVKVFDPRAGIAAGETRLSLRLADGREIEASPGTGDGEFEVASLPASAAVTAIGVRFAYPPQRTRWVATTDSTKQLYLIGFDALAIGAIPGGPLALDVQADGSLLADPPDRLHFKRTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLF8</accession>
    <name>A0A0S2DLF8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3986</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59328">
        <property type="protein sequence ID" value="ALN59328"/>
        <property type="gene ID" value="GLE_3986"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3986"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3923"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="44" mass="4651" checksum="3C136D0E1117C3B3" modified="2016-02-17" version="1">MGLRFGAVDVRGCRFYAVPAVGNETGRSPVGAAQAATAVMQRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLG9</accession>
    <name>A0A0S2DLG9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 8">Corrinoid adenosyltransferase</fullName>
            <ecNumber evidence="5 8">2.5.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cob(II)alamin adenosyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Cob(II)yrinic acid a,c-diamide adenosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">cobO</name>
        <name evidence="12" type="ORF">BV903_01320</name>
        <name evidence="13" type="ORF">FE772_20065</name>
        <name evidence="11" type="ORF">GLE_4089</name>
    </gene>
    <organism evidence="11 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">C3</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">B25</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>2 ATP + 2 cob(II)alamin + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)alamin + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate</text>
            <dbReference type="Rhea" id="RHEA:28671"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="2.5.1.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>2 ATP + 2 cob(II)yrinate a,c diamide + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)yrinate a,c-diamide + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate</text>
            <dbReference type="Rhea" id="RHEA:11528"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:58503"/>
            <dbReference type="ChEBI" id="CHEBI:58537"/>
            <dbReference type="EC" id="2.5.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 2/7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the Cob(I)alamin adenosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.17" evidence="5 8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000002">
        <property type="protein sequence ID" value="OPD65917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948774.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4089"/>
    <dbReference type="EnsemblBacteria" id="ALN59431">
        <property type="protein sequence ID" value="ALN59431"/>
        <property type="gene ID" value="GLE_4089"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65917">
        <property type="protein sequence ID" value="OPD65917"/>
        <property type="gene ID" value="BV903_01320"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4089"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4031"/>
    <dbReference type="OMA" id="VVKHAFK"/>
    <dbReference type="OrthoDB" id="1690483at2"/>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00233"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008817">
        <property type="term" value="F:cob(I)yrinic acid a,c-diamide adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003724">
        <property type="entry name" value="CblAdoTrfase_CobA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025826">
        <property type="entry name" value="Co_AT_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12557">
        <property type="entry name" value="Co_AT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02572">
        <property type="entry name" value="CobA_CobO_BtuR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015617">
        <property type="entry name" value="Adensltrnsf_CobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00708">
        <property type="entry name" value="cobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Co_AT_N" evidence="10">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR015617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN59431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OPD65917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW27592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="210" mass="22936" checksum="10F05AF4B9CACF1C" modified="2016-02-17" version="1">MSEDDGDRAGFAAASEDKHRERMQRKKELIDRKVARATIERGVLVVNTGNGKGKSSSGFGMLARSLGHGFKCGVVQFIKGSFATGEEAFFRRFEELDYHVMGEGFTWETQDKQRDIAAAQAAWAVAARMLGDEAYDFVLLDELNIALAHRYVAVDDVLAAVAARPPRQHVVITGRGAPDALIEAADTVTDMRVVKHAFKAGIKAQKGVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLP6</accession>
    <name>A0A0S2DLP6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ThiJ/PfpI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3888</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948625.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3888"/>
    <dbReference type="EnsemblBacteria" id="ALN59231">
        <property type="protein sequence ID" value="ALN59231"/>
        <property type="gene ID" value="GLE_3888"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3888"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3827"/>
    <dbReference type="OMA" id="DAWYRLF"/>
    <dbReference type="OrthoDB" id="1421548at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="1">
        <location>
            <begin position="4"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="190" mass="19824" checksum="B095EADF5F6DC2E0" modified="2016-02-17" version="1">MTQRIVLLMIDRPADWEYAPLAGAAHAWFGIDVVSASIDAAPLTTMGGLSLQPQRRLAELDPGDGDLWVVPGSPLWDEAPAPAPIVQALRERAARGGAIAGICGGTRALAAAGLLNERAHTSNEPGYLDAVPGYSGQAQYREQACVSTGGIVTAPGTSPVSFAEACLWLVAPEQADGIAQMRAMFARDFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLR7</accession>
    <name>A0A0S2DLR7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4124 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BV903_04255</name>
        <name evidence="4" type="ORF">GLE_4201</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000008">
        <property type="protein sequence ID" value="OPD65139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4201"/>
    <dbReference type="EnsemblBacteria" id="ALN59543">
        <property type="protein sequence ID" value="ALN59543"/>
        <property type="gene ID" value="GLE_4201"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65139">
        <property type="protein sequence ID" value="OPD65139"/>
        <property type="gene ID" value="BV903_04255"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4201"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4143"/>
    <dbReference type="OMA" id="AVKAYCK"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025392">
        <property type="entry name" value="DUF4124"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13511">
        <property type="entry name" value="DUF4124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595234" description="DUF4124 domain-containing protein" evidence="2">
        <location>
            <begin position="33"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4124" evidence="3">
        <location>
            <begin position="22"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD65139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="153" mass="15615" checksum="36120F269510AA10" modified="2016-02-17" version="1">MSRTSRISARRALPALGLGAILAALTAFPAAATDLYQWKDAQGVTHYSDSPPPAQSGSGQVKNRVIRNKSGTPSQTAAASAPAENSQCTSARANLKQLQSSAQVGVDNDGDGKPDSALDAQQRAAQVQLAEASIRAYCTPAPAAAGQTGEPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMG7</accession>
    <name>A0A0S2DMG7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">HlyD family efflux transporter periplasmic adaptor subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_20630</name>
        <name evidence="1" type="ORF">GLE_4208</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948871.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4208"/>
    <dbReference type="EnsemblBacteria" id="ALN59549">
        <property type="protein sequence ID" value="ALN59549"/>
        <property type="gene ID" value="GLE_4208"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4208"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4150"/>
    <dbReference type="OMA" id="SVWLDTV"/>
    <dbReference type="OrthoDB" id="1432684at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="418" mass="44258" checksum="023F315A8BE5B4F5" modified="2016-02-17" version="1">MDIAKSPAARRPFWKRHRLALAAAAGLALCGVAALWNLGQAMPSVARTQVWIDDARRGPMQVEIRASGTLVPKDIRWITAGTTATVQQVVVLPGARVEPDTVVLRLFNPAAAANLGKAEAALAGAEADVAAKRTALTSELLDHESTLAEAESTFRINQMKADASVLGEQKGVISRLEARQATITADQNRQLLEIQRKRFAAFRQNVQAQIRASEAQRDGARSALEIARQEAASLVVVAGISGILQQVVAEPGQQVAAGANLARVARPEALLARLSVPEVQAKDLVLGLPVNIDTHNGVVEGRIGRIDPAVRDGSVAIDVELASKLPPGARPDLSVDGRIVLGLQKDVVSIGRPPLAAPNSVSSLFVLPAGADVARRTSVTYGAASSDRIAVLAGLRNGDRVILSDTSQWNQFEALRIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMM9</accession>
    <name>A0A0S2DMM9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GntR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4686</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949236.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4686"/>
    <dbReference type="EnsemblBacteria" id="ALN60027">
        <property type="protein sequence ID" value="ALN60027"/>
        <property type="gene ID" value="GLE_4686"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4686"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4621"/>
    <dbReference type="OMA" id="HMNPQGI"/>
    <dbReference type="OrthoDB" id="1024978at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="473" mass="51893" checksum="383D1B3163D73F34" modified="2016-02-17" version="1">MSQELLYERLAERMRRQIQRGVLRAGERLPSLRRLGRDQRISLATAVEAYQQLEREGLIEARPRSGYYVRAAPAAPPRSHRARHLSRAPTPMRNPALLGVLDVQSRRDLVPLHAATPAAALLPSAALAASVTRAMRRDPAAALGYTVPQGLPALRERIAQRYAQCGVEIDPDEVIVTAGAMEAISLTLRTLTRPGDIVILETPTYHGLLQAVAAHGLRVLEIPNHPGRGLDPAQLRELLERHAVRAALLVPNFNNPLGSLTGETAKREIVAACAAHGTVLIEDDLYGELAYSGERPAPLRRYDDGEHVVTCGSYSKILAPGLRVGWMLGGRRRSELLRTKSFSTVATATLPQMALIDFLARHDIERGLRRLRRALAGNAQAYRQALLDHWPEGTCVAEPAGGMTLWVELPERIDGQALFEAALARGIGILPGHLFSNRGDYTHHVRLSCGQPWDRAMETALKTLGQLAKQLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMP0</accession>
    <name>A0A0S2DMP0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_11740</name>
        <name evidence="4" type="ORF">FE772_21360</name>
        <name evidence="2" type="ORF">GLE_4372</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000028">
        <property type="protein sequence ID" value="OPD63717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948999.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000028.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59713">
        <property type="protein sequence ID" value="ALN59713"/>
        <property type="gene ID" value="GLE_4372"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63717">
        <property type="protein sequence ID" value="OPD63717"/>
        <property type="gene ID" value="BV903_11740"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4372"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4311"/>
    <dbReference type="OrthoDB" id="2076446at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595282" evidence="1">
        <location>
            <begin position="31"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="68" mass="7225" checksum="D99E108045F21DD6" modified="2016-02-17" version="1">MPLFRTHRSARLWLGAFALAAFGFGFAVQAASSAPPNRALCSLKVCQDRCGGLPGWNPGNGQPCRCCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMR0</accession>
    <name>A0A0S2DMR0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Efflux ABC transporter, permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLE_4210</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4210"/>
    <dbReference type="EnsemblBacteria" id="ALN59551">
        <property type="protein sequence ID" value="ALN59551"/>
        <property type="gene ID" value="GLE_4210"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4210"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4152"/>
    <dbReference type="OMA" id="ICCTIIA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017800">
        <property type="entry name" value="ADOP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03434">
        <property type="entry name" value="ADOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="22"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="332"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="369"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="684"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="744"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="775"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="9">
        <location>
            <begin position="26"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="311"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="9">
        <location>
            <begin position="424"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="717"/>
            <end position="804"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="811" mass="84719" checksum="D4A66470DB490BB9" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMV0</accession>
    <name>A0A0S2DMV0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Inner membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4536</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4536"/>
    <dbReference type="EnsemblBacteria" id="ALN59877">
        <property type="protein sequence ID" value="ALN59877"/>
        <property type="gene ID" value="GLE_4536"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4536"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4472"/>
    <dbReference type="OMA" id="CVLVWLW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007401">
        <property type="entry name" value="DUF454"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35813">
        <property type="entry name" value="PTHR35813"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04304">
        <property type="entry name" value="DUF454"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016789">
        <property type="entry name" value="DUF454"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="6"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR016789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="120" mass="13278" checksum="01D85545AD408E9D" modified="2016-02-17" version="1">MRWAWWLLAYASLGLGIVGIVVPGLPTVPFVLLSAYAAARGSQRLHARLLAHRQFGPMIRDWQAHGAVSRRAKRLAVSMMALCAAIMFLTSPKWWMAATGTAIMTVVAIWLWRRPEPPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMY6</accession>
    <name>A0A0S2DMY6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59892">
        <property type="protein sequence ID" value="ALN59892"/>
        <property type="gene ID" value="GLE_4551"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4551"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4487"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="46" mass="5304" checksum="8A0DBC4B87590D04" modified="2016-02-17" version="1">MSAAAWRPERRASGLKALPQQPRKPWGLLWEGLQPRRFCVRCRAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN01</accession>
    <name>A0A0S2DN01_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FE772_21130</name>
        <name evidence="9" type="ORF">GLE_4322</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948960.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4322"/>
    <dbReference type="EnsemblBacteria" id="ALN59663">
        <property type="protein sequence ID" value="ALN59663"/>
        <property type="gene ID" value="GLE_4322"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4322"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4261"/>
    <dbReference type="OMA" id="PWIIRRE"/>
    <dbReference type="OrthoDB" id="692375at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="188"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="249"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN59663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="459" mass="50020" checksum="42978A826F12A6FF" modified="2016-02-17" version="1">MKAAPSLRARLLWRMLGLQCLLLTAFGVLVALSLHAANVAVDEDNAVEVLQNALQRDAHGRLSLRDTADLRELREEMPRLWYVIRDEAGRELRHGPVPAEFAGIGGALDRVSQARLGYLFGDDRIAGARLKRVDAGFGEVRILTTEKGRVMSASRLMWMALSLFATLILPLLAVMALVTAIATPMVVRWSLRSLEPVIAQARALDVERRGARLPEAGVPDEVRPLVSAVNGALARYDDGFERRRRFLADAAHELRTPIAILSARLESMPALPERERLLQDVARMSVLAEHLLDLQRLDRPEPQLEALDLGEIGQRVAADLAPLAIAAGYELAFEAWAKPVPVNGDALALERVLVNLVQNAIEYGGNRGTVTIRVAIEASDGVVEVCDEGPGIPPAHREHVFERFFRLQPHERGAGVGLNLVRDIVRLHRGAVEATDAQGGGACFRVALPLAAARGKGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNH6</accession>
    <name>A0A0S2DNH6_LYSEN</name>
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        <submittedName>
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        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">GLE_4759</name>
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        <name type="scientific">Lysobacter enzymogenes</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_MTAY01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4759"/>
    <dbReference type="EnsemblBacteria" id="ALN60100">
        <property type="protein sequence ID" value="ALN60100"/>
        <property type="gene ID" value="GLE_4759"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63351">
        <property type="protein sequence ID" value="OPD63351"/>
        <property type="gene ID" value="BV903_13755"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4759"/>
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    <dbReference type="OMA" id="MVEFELF"/>
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    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0008689">
        <property type="term" value="F:3-demethylubiquinone-9 3-O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="entry name" value="3_dmu_93_MTrfase"/>
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        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
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    </dbReference>
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            <begin position="4"/>
            <end position="119"/>
        </location>
    </feature>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="159" mass="17195" checksum="E2F4DBABD0B75544" modified="2016-02-17" version="1">MTPKNTICLWYDGAALEAAEFYAKTFPDSAVTAIHHAPGDYPDGHQGDVLTVEFTVAGIPCVGLNGGPAFKHDEAFSFQIATDDQAETDRLWDAIVGNGGKESACGWCKDKWGLSWQITPRALLEAFTDPDRAAAKRAFDAMMTMGKIDIAKIEAARRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNJ3</accession>
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="PATRIC" id="fig|69.6.peg.4598"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="37" mass="3980" checksum="5D016757FD24381C" modified="2016-02-17" version="1">MNRAILNRAVSNRTVSNRTASSRTVSSRTVSSRAASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNL3</accession>
    <name>A0A0S2DNL3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF924 family protein</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_10355</name>
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            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="69.GLE_4799"/>
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        <property type="gene ID" value="BV903_10355"/>
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    </dbReference>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD63986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="185" mass="21054" checksum="E8AF29638D848B5B" modified="2016-02-17" version="1">MSVTAQEVVAFWRDAGPDRWFDRSDRFDQQCRSGFLEAHFAAARREHDDWVERDAESALALLILLDQIPRNVFRGSAHAFATDPLARHYARRALELGHDQKIEAPLRPFFYLPLEHSEDLADQQRSVELHRALPPSADGSDPAQWAVQHQQIVERFGRFPHRNPALGRATTAEEQAYLDGGGFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNP1</accession>
    <name>A0A0S2DNP1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyoverdine biosynthesis protein PvcA</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Pyoverdine/dityrosine biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_23390</name>
        <name evidence="1" type="ORF">GLE_4813</name>
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    <organism evidence="1 3">
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            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW28879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4813"/>
    <dbReference type="EnsemblBacteria" id="ALN60154">
        <property type="protein sequence ID" value="ALN60154"/>
        <property type="gene ID" value="GLE_4813"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4813"/>
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    <dbReference type="OMA" id="TRDDWLT"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="313" mass="34287" checksum="371BB5329B1423DB" modified="2016-02-17" version="1">MKHRRSPARCACKGALCSDACVRPHLDRVARAVERAQPIVFILPSFPGKSPNPAKVLGPMPDMAERASLTFLNTLCRTIGERHAPGARLILCSDGRVFSDAVGLHEPDVTAYQRGIESIIEELRLEALSTFNLDDLFPGCDFAEMRSRLMARHGRPLDDLRAAVRAGGEARQIYCGITRFLFEDALRPDLGISRTALQKLCRERAYHVVQRSKAWDGLLAGEFPDAVRLSIHPQGCGSGKIGIHMMATADEWLTPWHGVAALANGSFTLIKRREAEAAGARMVFRDGRPSHYVLRAASPRDPTGAACGAKEPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNP4</accession>
    <name>A0A0S2DNP4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4938</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60279">
        <property type="protein sequence ID" value="ALN60279"/>
        <property type="gene ID" value="GLE_4938"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4938"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4866"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="44" mass="5458" checksum="D20B510933FE38E9" modified="2016-02-17" version="1">MTWVKPVRLKAVVACQGRLARQARWRGRGLRRSYRERPWFRFRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNQ3</accession>
    <name>A0A0S2DNQ3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_12005</name>
        <name evidence="3" type="ORF">FE772_21620</name>
        <name evidence="1" type="ORF">GLE_4427</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000028">
        <property type="protein sequence ID" value="OPD63767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949046.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000028.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59768">
        <property type="protein sequence ID" value="ALN59768"/>
        <property type="gene ID" value="GLE_4427"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63767">
        <property type="protein sequence ID" value="OPD63767"/>
        <property type="gene ID" value="BV903_12005"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4427"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4365"/>
    <dbReference type="OrthoDB" id="2004462at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046197">
        <property type="entry name" value="DUF6229"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19740">
        <property type="entry name" value="DUF6229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD63767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="65" mass="6696" checksum="1DBB8A0181A59F18" modified="2016-02-17" version="1">MQNDDHVSDWLNGADSVDGLSNPAGPLYIEGAAATEDALTSPNEANMFSTRTAITCIGAACCFCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNT8</accession>
    <name>A0A0S2DNT8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rhamnosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949246.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4700"/>
    <dbReference type="EnsemblBacteria" id="ALN60041">
        <property type="protein sequence ID" value="ALN60041"/>
        <property type="gene ID" value="GLE_4700"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4700"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4634"/>
    <dbReference type="OMA" id="FARVGPF"/>
    <dbReference type="OrthoDB" id="957193at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-0808">Transferase</keyword>
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        <location>
            <begin position="61"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="337" mass="37276" checksum="4219F529E826ED01" modified="2016-02-17" version="1">MNDAGFPRVDDEPADRADGPSGARAPASVDPDSYGAVAVLWQPQPEHVDHLERVRAACRHLIAVDNSPHADAALHARLRARGIEVLHNGNRGGISGAYNRGAAALYAAGREVVFLLDQDSQLGADFFDGMMRACARARVDGEAFIVGPKVFEVNLGRYLPVFAPQPRMPKPERIDERRDGLVPTLFVISSGSAVSAAAFARIGEFREDYFIEYVDIEYGLRATRNGVPVLVNAAVEMHQQVGQYVKRGIFSTSNHVAWRRYYASRNAVHALRSNASRWSIHWLIELLTLHQVACVLVCEEHKLRKVVAIAVGYFDGLFGKLGTFEQRHPRVAAFCRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNV3</accession>
    <name>A0A0S2DNV3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FE772_23800</name>
        <name evidence="9" type="ORF">GLE_4903</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949403.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4903"/>
    <dbReference type="EnsemblBacteria" id="ALN60244">
        <property type="protein sequence ID" value="ALN60244"/>
        <property type="gene ID" value="GLE_4903"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4903"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4834"/>
    <dbReference type="OMA" id="ADHTHLC"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="165"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="227"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN60244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW28221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="431" mass="47433" checksum="D876698BE4697CD2" modified="2016-02-17" version="1">MATPDRPAAPARPRSSLRQRILLGLFGYTALLSIAVVVQGFFVNEHAEHLVWTSLMNTEMDYFVERSRSDPDYRWSDTQALSLYDSATRPPPRELAALAPGVHDEVVVAGVEYVTLVRDIDGRRLTLALDIDDMEHREFDLALTIAGSAVTTLLLLGVVIGWGVRRLVRPLTNMAQRIGGLRPDRSGQRVDVPESASSELVVIADAVNDYLQRNDRFVERERAFIDSASHELRTPISVIAGAAEIALEQNELPAGARHQINRIRRASRDVEQLISLLLVLAKDPKRLSASSDRVALDHLLPEIVEDHRHLTRDKDLTLAVAPLPPCEILAPLPIVQAAIGNLLRNAIENSDRGEIAIRLHPDATVTIDDPGHGMTPEEISAIYARVARGGREGGGIGLDLISRLCEHLGWTLRFDKAERGTRTTLALKATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP70</accession>
    <name>A0A0S2DP70_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UPF0114 protein BV903_06870</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BV903_06870</name>
        <name evidence="9" type="ORF">FE772_23990</name>
        <name evidence="7" type="ORF">GLE_4948</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the UPF0114 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000012">
        <property type="protein sequence ID" value="OPD64747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949437.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000012.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60289">
        <property type="protein sequence ID" value="ALN60289"/>
        <property type="gene ID" value="GLE_4948"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64747">
        <property type="protein sequence ID" value="OPD64747"/>
        <property type="gene ID" value="BV903_06870"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4948"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4876"/>
    <dbReference type="OMA" id="HTIMWQV"/>
    <dbReference type="OrthoDB" id="1466526at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00143">
        <property type="entry name" value="UPF0114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005134">
        <property type="entry name" value="UPF0114"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020761">
        <property type="entry name" value="UPF0114_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38596">
        <property type="entry name" value="PTHR38596"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03350">
        <property type="entry name" value="UPF0114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00645">
        <property type="entry name" value="HI0507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN60289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD64747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW28251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="213" mass="23172" checksum="912A1BC01F7E6C0F" modified="2016-02-17" version="1">MTDPKINRLNPLPALIFSSRWLQLPLYLGLIVAQGVYVFQFVRELIHLITDAANLTEQAIMLIVLGLIDVVMISNLLVMVIVGGYETFVSRLRLEGHPDQPEWLSHVNASVLKVKLAMAIIGISSIHLLKTFIGAGSLGLPLCGTPEAYEMARAVAAMTANGTLDKAMRCTDITEQGVMWQALIHLLFIVSAVGIAWTDKLMSAGIKAAKNGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP97</accession>
    <name>A0A0S2DP97_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_07985</name>
        <name evidence="3" type="ORF">GLE_5198</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000016">
        <property type="protein sequence ID" value="OPD64475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949626.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60539">
        <property type="protein sequence ID" value="ALN60539"/>
        <property type="gene ID" value="GLE_5198"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64475">
        <property type="protein sequence ID" value="OPD64475"/>
        <property type="gene ID" value="BV903_07985"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5198"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5117"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595927" evidence="2">
        <location>
            <begin position="21"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD64475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="146" mass="15715" checksum="8B8E4C92933D82DB" modified="2016-02-17" version="1">MLRLPLAAALALLLSAPAFAQAPAAKPIATKSAAIPAPKLAPPALKPQAQQTHAPPGAQRPQDELYRQSPAAARLAEPGEPGFDLQSPQPLVRWGEGDPQRTRQDSENQRTRCAHSIKQMREAGSDERGKREGRARRDCRGVSFGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPB1</accession>
    <name>A0A0S2DPB1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60404">
        <property type="protein sequence ID" value="ALN60404"/>
        <property type="gene ID" value="GLE_5063"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5063"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4991"/>
    <dbReference type="OMA" id="VRKAVNW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014825">
        <property type="entry name" value="DNA_alkylation"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08713">
        <property type="entry name" value="DNA_alkylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="277" mass="29979" checksum="584B9B10DF13A4F4" modified="2016-02-17" version="1">MPKAAAKTATQTSAAISAPNRSRATARADGKATAAARKAAQAAFAAQPLSARLEQALQALRAAADARHRDGMARFAIPNQRAFGVPMAQVQAVAKRLGRDRALAAALWDSGWYEARLLAAYLDDPAAVTAAQMDRWARDFDNWAVCDTVCFALFDRSPLAWRKIEQWARREDEFVRRAAFALLASKSVHDKSAGDEQFLRGLDLVEAHAGDARNFVRKAVNWALRSIGKRNAALHAAALATAARLAASADPVARWNGKDALRELNGPATARRLARKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPG0</accession>
    <name>A0A0S2DPG0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Copper chaperone PCu(A)C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_24860</name>
        <name evidence="2" type="ORF">GLE_5127</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5127"/>
    <dbReference type="EnsemblBacteria" id="ALN60468">
        <property type="protein sequence ID" value="ALN60468"/>
        <property type="gene ID" value="GLE_5127"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5127"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5052"/>
    <dbReference type="OMA" id="TVQDAWV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007410">
        <property type="entry name" value="PCuAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036182">
        <property type="entry name" value="PCuAC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36302">
        <property type="entry name" value="PTHR36302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04314">
        <property type="entry name" value="PCuAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110087">
        <property type="entry name" value="SSF110087"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242277" evidence="1">
        <location>
            <begin position="24"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="159" mass="16982" checksum="8A8A28FA9BF057C4" modified="2016-02-17" version="1">MRNPFRHSLLFAAALLCAPIAFAQTGAASATGAQVAIDAPWVRATVPRQPATGAFMRLTAARDLRLVGARSPAADHVEVHEMAMQGQMMRMRQVAALDLPKGRAVALAPGGYHLMLIGLQRPLRAGEKVALTLLFEDADGKRSEQQVHAEVRPLATPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPG9</accession>
    <name>A0A0S2DPG9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">DNA polymerase I</fullName>
            <ecNumber evidence="3 13">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13 17" type="primary">polA</name>
        <name evidence="17" type="ORF">GLE_4940</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Single-chain monomer with multiple functions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 13">Belongs to the DNA polymerase type-A family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="3 13"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949429.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4940"/>
    <dbReference type="EnsemblBacteria" id="ALN60281">
        <property type="protein sequence ID" value="ALN60281"/>
        <property type="gene ID" value="GLE_4940"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4940"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4868"/>
    <dbReference type="OMA" id="NRPPMPD"/>
    <dbReference type="OrthoDB" id="1220182at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09898">
        <property type="entry name" value="H3TH_53EXO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020046">
        <property type="entry name" value="5-3_exonucl_a-hlix_arch_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002421">
        <property type="entry name" value="5-3_exonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019760">
        <property type="entry name" value="DNA-dir_DNA_pol_A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001098">
        <property type="entry name" value="DNA-dir_DNA_pol_A_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020045">
        <property type="entry name" value="DNA_polI_H3TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018320">
        <property type="entry name" value="DNA_polymerase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002298">
        <property type="entry name" value="DNA_polymerase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10133">
        <property type="entry name" value="PTHR10133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01367">
        <property type="entry name" value="5_3_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02739">
        <property type="entry name" value="5_3_exonuc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00476">
        <property type="entry name" value="DNA_pol_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00868">
        <property type="entry name" value="DNAPOLI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00475">
        <property type="entry name" value="53EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00482">
        <property type="entry name" value="POLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="SSF47807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00593">
        <property type="entry name" value="pola"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00447">
        <property type="entry name" value="DNA_POLYMERASE_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="11 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 13" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="9" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6 13 17" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="53EXOc" evidence="15">
        <location>
            <begin position="2"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="3'-5' exonuclease" evidence="14">
        <location>
            <begin position="328"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="POLAc" evidence="16">
        <location>
            <begin position="684"/>
            <end position="891"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ALN60281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="927" mass="100939" checksum="DE3AC9C90ECEB52E" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPH4</accession>
    <name>A0A0S2DPH4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5044</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5044"/>
    <dbReference type="EnsemblBacteria" id="ALN60385">
        <property type="protein sequence ID" value="ALN60385"/>
        <property type="gene ID" value="GLE_5044"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5044"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4972"/>
    <dbReference type="OMA" id="APHTEEW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="307" mass="32829" checksum="13A418C67221B373" modified="2016-02-17" version="1">MTMTSESPSARGPAAPLHVLGALALELKGDAAVQRSALARHDAGALSEKIARDLAGFAADTAALDLVTVGAHYDPVELLRPGWPLHRELDELAARAPRERGAEQAGRVIAFGAHDDQLPGALTPSPDFAGGPLRLVPFALSGSPELVARVGETLESSLLERGMAGADTALAAQAAFGLKVEHARYLTVHDLAAMMALQYDHAGLGPLWPLLETALLQPEGEQWLDALPEPLVHYADGEARIALFSPAAWHARYAPEAPCDTAECRDKLNRRYQHFEARLRQIAAVLGAHAVPVTFVHCDGEQPREEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPL2</accession>
    <name>A0A0S2DPL2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5326</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60667">
        <property type="protein sequence ID" value="ALN60667"/>
        <property type="gene ID" value="GLE_5326"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5326"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5243"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="47" mass="5318" checksum="0686A047E11B5FD2" modified="2016-02-17" version="1">MDIGCGQLQRLGVDPMPQLKRPASGPSLWINRNVDKRKRPPFGSRFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPN0</accession>
    <name>A0A0S2DPN0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DUF3526 domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_24355</name>
        <name evidence="7" type="ORF">GLE_5024</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949495.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5024"/>
    <dbReference type="EnsemblBacteria" id="ALN60365">
        <property type="protein sequence ID" value="ALN60365"/>
        <property type="gene ID" value="GLE_5024"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5024"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4952"/>
    <dbReference type="OMA" id="PHRMVHY"/>
    <dbReference type="OrthoDB" id="920524at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021913">
        <property type="entry name" value="DUF3526"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12040">
        <property type="entry name" value="DUF3526"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="440"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN60365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW28313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="467" mass="49956" checksum="6D078FAE8AFE7A80" modified="2016-02-17" version="1">MSASLTGYEWTLLRRDRRAWWALLALAALVLLAFAFDLAGVAAGNAAKNEAARAERARWLGQGEKDPHSAAHYSIFAFKPTTALAALDPGAEPFVGQTVWLEAHVQNDMLYRPQGDASPLQRAGLASPASLLIAFAPLVAFLLAFTAVAMDRERGTLRLALGAALRPRAIVAAKALAIWSALMLALLAPVVAASAVASAALGALNADLALRLALWAAAMALYLGVLTALGVSVSLLARSVRGALALLFGLWIALALALPRWASSAVEAAHPLPSSQQVKQQLQDEAPSFWTAEEAKKHRQALLAQYGAKDVGDMRVDARGAELDLSERHSHQVFDRVLGGFYDRVAAQDRAFAAWSWLSPAAAMQSLSPMLAGSDFGHHRRFIDAAEQYRRALVNRMNEDVMAHPLNGAQPRHTNDESLWAQVPQFQAPQPALAANWRNAAPALAGLFGWAALAAGLLALAARRLRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPQ4</accession>
    <name>A0A0S2DPQ4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Isopropylmalate/homocitrate/citramalate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_08095</name>
        <name evidence="4" type="ORF">FE772_25275</name>
        <name evidence="2" type="ORF">GLE_5223</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000016">
        <property type="protein sequence ID" value="OPD64495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949645.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5223"/>
    <dbReference type="EnsemblBacteria" id="ALN60564">
        <property type="protein sequence ID" value="ALN60564"/>
        <property type="gene ID" value="GLE_5223"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64495">
        <property type="protein sequence ID" value="OPD64495"/>
        <property type="gene ID" value="BV903_08095"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5223"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5141"/>
    <dbReference type="OMA" id="RVTTYYN"/>
    <dbReference type="OrthoDB" id="1907687at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011721">
        <property type="entry name" value="CHP02096"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02096">
        <property type="entry name" value="TIGR02096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="16"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="141" mass="15816" checksum="5E45D7ED08BF6EC2" modified="2016-02-17" version="1">MTEAARHHDRATELVLSYYAAFNRADWDAMLATLGDEVAHDLNQGARETGREAFAAFLQRMARHYREQLRDIVVMASADGTRAAAEYVVHGEYLATDPGLPEARGQKYVLPGGAFFEIREGKIQRVTNYYNLDHWVAQVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPT9</accession>
    <name>A0A0S2DPT9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 8">DNA replication and repair protein RecF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">recF</name>
        <name evidence="11" type="ORF">FE772_25790</name>
        <name evidence="10" type="ORF">GLE_5337</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7 8">The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the RecF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949731.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5337"/>
    <dbReference type="EnsemblBacteria" id="ALN60678">
        <property type="protein sequence ID" value="ALN60678"/>
        <property type="gene ID" value="GLE_5337"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5337"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5254"/>
    <dbReference type="OMA" id="GESWSYA"/>
    <dbReference type="OrthoDB" id="891841at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00365">
        <property type="entry name" value="RecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001238">
        <property type="entry name" value="DNA-binding_RecF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018078">
        <property type="entry name" value="DNA-binding_RecF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042174">
        <property type="entry name" value="RecF_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32182:SF0">
        <property type="entry name" value="PTHR32182:SF0"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00611">
        <property type="entry name" value="recf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00617">
        <property type="entry name" value="RECF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00618">
        <property type="entry name" value="RECF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 8" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="AAA" evidence="9">
        <location>
            <begin position="22"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="30"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN60678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW28912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="361" mass="40527" checksum="D1102EBB3B0CF628" modified="2016-02-17" version="1">MHVTRLDARGLRRFADVSLLPAPGINLITGENGAGKTSLLEALHLMAYGRSFRGRVRDGLIRSGDPALEVFVEWQELRRDQRRKAGLRHSGQDWVGRLDGASVSQLGELCAALAVVSFEPGSHSLITGPGEIRRRYLDWGLFHVEHDFTPLWRRYTRALKQRNALLKARARDGQLDAWDRELSESGEPLSRRRQQYLDELQPRFAALAAELAPGLGSIRLDYVPGWRREEFPLADALLLARERDQQQGFTSVGPHRADWRIGYGAIPGREALSRGQAKLVALVALLAQAEQHAQVQGEWPVIALDDLASELDRRHQRRVLERLIASRAQVFITGTEAPPALAEMDVEIARFHVEHGNLKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPV9</accession>
    <name>A0A0S2DPV9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Undecaprenyl-diphosphatase</fullName>
            <ecNumber evidence="4 14">3.6.1.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">Bacitracin resistance protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12 14">Undecaprenyl pyrophosphate phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">uppP</name>
        <name evidence="16" type="ORF">FE772_24930</name>
        <name evidence="15" type="ORF">GLE_5144</name>
    </gene>
    <organism evidence="15 17">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="15 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">C3</strain>
        </source>
    </reference>
    <reference evidence="16 18" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>di-trans,octa-cis-undecaprenyl diphosphate + H2O = di-trans,octa-cis-undecaprenyl phosphate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:28094"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="EC" id="3.6.1.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cell membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="14">Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the UppP family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.27" evidence="4 14"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949586.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5144"/>
    <dbReference type="EnsemblBacteria" id="ALN60485">
        <property type="protein sequence ID" value="ALN60485"/>
        <property type="gene ID" value="GLE_5144"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5144"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5068"/>
    <dbReference type="OMA" id="IEGPFRD"/>
    <dbReference type="OrthoDB" id="1826154at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050380">
        <property type="term" value="F:undecaprenyl-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016311">
        <property type="term" value="P:dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01006">
        <property type="entry name" value="Undec_diphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003824">
        <property type="entry name" value="UppP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30622">
        <property type="entry name" value="PTHR30622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02673">
        <property type="entry name" value="BacA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="6 14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14" id="KW-0133">Cell shape</keyword>
    <keyword evidence="14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 14 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ALN60485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QCW28412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="268" mass="28374" checksum="B9C8A13B3AA143D1" modified="2016-02-17" version="1">MTDLLAALLLGIIEGITEFLPISSTGHLLIAQHWLGARSDLFNISIQAGAILAVVVIYWKRLWGLAVGFTQRDNLDYLLKLGLAFGITGVLGIVVKKAGFTLPDHVAPIAWALVLGGVWMIAAEHFAAKRAAALGERSDITWTVATLVGIAQVVAGVFPGTSRSAATIFVALLAGTTSRAAATEFAFLVGIPTMFAASGYELMGVLGTPAAAQEDWSALAVAFVASAVTAFIAVKWLLRYIQSHRFTAFAIYRLVFGVALLWLMPSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ97</accession>
    <name>A0A0S2DQ97_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Class I SAM-dependent rRNA methyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">rRNA large subunit methyltransferase I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BV903_24955</name>
        <name evidence="8" type="ORF">FE772_25380</name>
        <name evidence="6" type="ORF">GLE_5244</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">C3</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000102">
        <property type="protein sequence ID" value="OPD61186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949660.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000102.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5244"/>
    <dbReference type="EnsemblBacteria" id="ALN60585">
        <property type="protein sequence ID" value="ALN60585"/>
        <property type="gene ID" value="GLE_5244"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61186">
        <property type="protein sequence ID" value="OPD61186"/>
        <property type="gene ID" value="BV903_24955"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5244"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5163"/>
    <dbReference type="OMA" id="VMDVFDY"/>
    <dbReference type="OrthoDB" id="468283at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041532">
        <property type="entry name" value="RlmI_PUA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019614">
        <property type="entry name" value="SAM-dep_methyl-trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10672">
        <property type="entry name" value="Methyltrans_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17785">
        <property type="entry name" value="PUA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PUA_3" evidence="5">
        <location>
            <begin position="13"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltrans_SAM" evidence="4">
        <location>
            <begin position="178"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN60585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD61186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW28485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="389" mass="43455" checksum="C75A025853D5689A" modified="2016-02-17" version="1">MTTELPTVRLKNAWKSTHPWIFQRLVDKPAQRPKPGSIVEVIGVDGEWIGRGFYNGHSRIALRMLENDPDVAVDADWFARKIAAAVSLRRDVLRLDEVSDAWRVVHSEGDGISGLVVDRYGDLLVVEYFSAGAFRHREWIYDALRAQFPGCRFYAFADEHVQKQESFDFRGTEAVPPAVITEYGIKFRADPAGAHKTGFFADQRENREWLSQQVAGKRVLDLCCNTGGFGVYAKARGAEEVIGVDIDADVINIAKGNAKLNGAHVKFVQADIFPYLRDMGNAGERFDVVILDPAKMTRDREQVIPALKKYLDMNKLALSVVKPGGLFATFSCTGLVSEDQFLDMLRRAAFYAGRTVQVLRVAGAGADHPWLAQVPESRYLKAVFCRVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQA4</accession>
    <name>A0A0S2DQA4_LYSEN</name>
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        <submittedName>
            <fullName evidence="6">Peptidase, families S8 and S53/proprotein convertase P-domain protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FE772_00545</name>
        <name evidence="6" type="ORF">GLE_5465</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60806">
        <property type="protein sequence ID" value="ALN60806"/>
        <property type="gene ID" value="GLE_5465"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5465"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5380"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04059">
        <property type="entry name" value="Peptidases_S8_Protein_convertases_Kexins_Furin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034182">
        <property type="entry name" value="Kexin/furin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002884">
        <property type="entry name" value="P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01483">
        <property type="entry name" value="P_proprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51829">
        <property type="entry name" value="P_HOMO_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
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        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
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        <location>
            <begin position="27"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="domain" description="P/Homo B" evidence="5">
        <location>
            <begin position="458"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN60806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW24377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="589" mass="61153" checksum="7038BFFEDA065C5B" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQH2</accession>
    <name>A0A0S2DQH2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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        <lineage>
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    <reference evidence="2 3" key="1">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60752">
        <property type="protein sequence ID" value="ALN60752"/>
        <property type="gene ID" value="GLE_5411"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5411"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5326"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="56" mass="6115" checksum="270E8A3FF0AE3EB0" modified="2016-02-17" version="1">MPAGAVPHVARLHASQRQDSRPAQSVTSPRRRNRNIRGQGKATRTDSPAASRALDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQK3</accession>
    <name>A0A0S2DQK3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5430</name>
    </gene>
    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60771">
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        <property type="gene ID" value="GLE_5430"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5430"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5346"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="40" mass="3913" checksum="EC912B17FBC10954" modified="2016-02-17" version="1">MRAPSGAASMGFAWGCVGANSNGNGNGNGNGKNGFRLSPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQL2</accession>
    <name>A0A0S2DQL2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5372</name>
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        <lineage>
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    <reference evidence="1 2" key="1">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
    <dbReference type="RefSeq" id="WP_057949757.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60713">
        <property type="protein sequence ID" value="ALN60713"/>
        <property type="gene ID" value="GLE_5372"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5372"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5287"/>
    <dbReference type="OrthoDB" id="2021048at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="133" mass="14486" checksum="15730F2C57E8215C" modified="2016-02-17" version="1">MQRLLLLIVLVAAAAFAYLHWFAAPAPRYSLAAIEQQPVPRAEFFALWREVADGLCAPGKSGSERVGVQACREHVDRAHERCLAAAGAPATIVGRAESRRWARPYLDCVLPAPSVCGGVQVRSDEDARRHCPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA22</accession>
    <name>A0A0S2DA22_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative phage protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_01090</name>
        <name evidence="1" type="ORF">GLE_0031</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945742.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0031"/>
    <dbReference type="EnsemblBacteria" id="ALN55390">
        <property type="protein sequence ID" value="ALN55390"/>
        <property type="gene ID" value="GLE_0031"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0031"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.38"/>
    <dbReference type="OMA" id="HASIEMI"/>
    <dbReference type="OrthoDB" id="296580at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="525" mass="56215" checksum="20AA6C4F4E236C0D" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA71</accession>
    <name>A0A0S2DA71_LYSEN</name>
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            <fullName evidence="1">Uncharacterized protein</fullName>
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        <name evidence="1" type="ORF">GLE_0036</name>
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    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="71" mass="7655" checksum="6FDE8FBC0E616246" modified="2016-02-17" version="1">MIVTLDHLRRAPGFGARPGFCAQGGREWFAYYGLDWSAFVRDGIQAETLEATGDALGLHLAAFARAEAARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA87</accession>
    <name>A0A0S2DA87_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase, GNAT family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_01385</name>
        <name evidence="2" type="ORF">GLE_0092</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945791.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0092"/>
    <dbReference type="EnsemblBacteria" id="ALN55451">
        <property type="protein sequence ID" value="ALN55451"/>
        <property type="gene ID" value="GLE_0092"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0092"/>
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    <dbReference type="GO" id="GO:0008080">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
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        <property type="entry name" value="GNAT_dom"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="166" mass="18785" checksum="ABF99074EDF98989" modified="2016-02-17" version="1">MNLVVRSATPADRAAVLALNLEAEALMSPMDHARLLALEAQSVYHRIVHDGQAAIAFLLAFDERADYDSPNYLWYRQRYPRFVYIDRIAVAASHRNRRIGGLLYDDVFAFAREHGVGTIAAEFYIEPFNEASSRFHARYGFGEVGTQWVAQGRKRVSLQIAAVPRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAG4</accession>
    <name>A0A0S2DAG4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chromosome partitioning protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">CobQ/CobB/MinD/ParA nucleotide binding domain</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">ParA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_22690</name>
        <name evidence="4" type="ORF">FE772_01760</name>
        <name evidence="2" type="ORF">GLE_0177</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
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    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000076">
        <property type="protein sequence ID" value="OPD61639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945852.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000076.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0177"/>
    <dbReference type="EnsemblBacteria" id="ALN55536">
        <property type="protein sequence ID" value="ALN55536"/>
        <property type="gene ID" value="GLE_0177"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61639">
        <property type="protein sequence ID" value="OPD61639"/>
        <property type="gene ID" value="BV903_22690"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0177"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.179"/>
    <dbReference type="OMA" id="VQCEYFA"/>
    <dbReference type="OrthoDB" id="729012at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="3"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="272" mass="28911" checksum="8C47ACA0F90B3536" modified="2016-02-17" version="1">MARIIAVANQKGGVGKTTTAVNLAAALAGTPKRVLLVDLDPQGNATMGSGIDKRQLEDSVCDVLLGEADAAATIVQAPEGFDLLPGNIDLTAAEIRLMNEDAREQRLKRALAPLRGNYDFIIVDCPPALSLLTLNALTAADSVIVPMQCEYYALEGLSALVETIEALKAQLNPSLEIEGVLRTMFDVRNNLANAVSADLTTHFGDRVFRTIVPRNVRLAEAPSYGQSIVGYDKASRGGIAYLGLAGEVLRRQRERDQAAAKTARAATAETPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAR4</accession>
    <name>A0A0S2DAR4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0274</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55632">
        <property type="protein sequence ID" value="ALN55632"/>
        <property type="gene ID" value="GLE_0274"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0274"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.273"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="61" mass="6465" checksum="3B028B694C5A11BC" modified="2016-02-17" version="1">MTQGHARRSEADGGWTACGGPWQSDRTRRPGFGRLSAHVKRGACKLSLKPAPLAPLPARAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAR9</accession>
    <name>A0A0S2DAR9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal RNA small subunit methyltransferase G</fullName>
            <ecNumber evidence="2">2.1.1.170</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">16S rRNA 7-methylguanosine methyltransferase</fullName>
            <shortName evidence="2">16S rRNA m7G methyltransferase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gidB</name>
        <name evidence="2 4" type="synonym">rsmG</name>
        <name evidence="4" type="ORF">FE772_01765</name>
        <name evidence="3" type="ORF">GLE_0178</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>guanosine(527) in 16S rRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(527) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42732"/>
            <dbReference type="Rhea" id="RHEA-COMP:10209"/>
            <dbReference type="Rhea" id="RHEA-COMP:10210"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.170"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.170" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945853.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0178"/>
    <dbReference type="EnsemblBacteria" id="ALN55537">
        <property type="protein sequence ID" value="ALN55537"/>
        <property type="gene ID" value="GLE_0178"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0178"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.180"/>
    <dbReference type="OMA" id="ICFPHLH"/>
    <dbReference type="OrthoDB" id="1590629at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070043">
        <property type="term" value="F:rRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00074">
        <property type="entry name" value="16SrRNA_methyltr_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003682">
        <property type="entry name" value="rRNA_ssu_MeTfrase_G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31760">
        <property type="entry name" value="PTHR31760"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02527">
        <property type="entry name" value="GidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003078">
        <property type="entry name" value="GidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00138">
        <property type="entry name" value="rsmG_gidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="2">
        <location>
            <begin position="137"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="221" mass="23283" checksum="89BC9C4351194E9F" modified="2016-02-17" version="1">MNAPTSLPPGLRGELEAGLSALALDPALAAPLLDYLALLARWNRTYNLTAVRDPHEMVGKHLLDSLAMHRYVEPLAARGGALADLGTGAGLPGIPLALVKPGLRVTLVESNGKKARFMREALRQLGLKDARVAESRIEAFAEPGAYDAITARALATLPLILELGGHLLKPGGVLLAMKGVRPDDEIAALPEGWEVRAVEPMAVPGLAAERHMVVVGRVGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAT0</accession>
    <name>A0A0S2DAT0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tat (Twin-arginine translocation) pathway signal sequence domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_02170</name>
        <name evidence="2" type="ORF">GLE_0267</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0267"/>
    <dbReference type="EnsemblBacteria" id="ALN55625">
        <property type="protein sequence ID" value="ALN55625"/>
        <property type="gene ID" value="GLE_0267"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0267"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.266"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033243118" evidence="1">
        <location>
            <begin position="21"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="547" mass="57440" checksum="6AAD90F7C25CFA11" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAU6</accession>
    <name>A0A0S2DAU6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bile acid:sodium symporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Sodium bile acid symporter family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_02320</name>
        <name evidence="2" type="ORF">GLE_0301</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0301"/>
    <dbReference type="EnsemblBacteria" id="ALN55659">
        <property type="protein sequence ID" value="ALN55659"/>
        <property type="gene ID" value="GLE_0301"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0301"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.298"/>
    <dbReference type="OMA" id="FFFYGLK"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016833">
        <property type="entry name" value="Put_Na-Bile_cotransptr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18640">
        <property type="entry name" value="PTHR18640"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13593">
        <property type="entry name" value="SBF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026166">
        <property type="entry name" value="UCP026166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="332" mass="35637" checksum="57047D58D52D4ADA" modified="2016-02-17" version="1">MSWLKRLRVDTFTLALLATVALAWKFPLQGAPAQWMDDFTDLAIAALFFLHGARLSREAILAGMLHWRLHLVIFASTFILFPLLGLALKPLSGHLLTPELYLGLLFLCTLPSTVQSSIAFTSMAGGNVPAAVCSASASSLLGVFLTPLLLSALAGAHGGMADPTEAIGKIMLQLLVPFVAGHFLRRWIGGWVERQRAVLRYTDQGTVLLVVYTAFSASMNSGLWQSTPLLALYVVIAVCALLLAVVMAATTFAARRLGFSREDEIAIVFCGSKKSLATGVPMAKILFATGALGAIVLPVMIFHQIQLIVCAQLAQRYARKAAGRAELEQAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB07</accession>
    <name>A0A0S2DB07_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55728">
        <property type="protein sequence ID" value="ALN55728"/>
        <property type="gene ID" value="GLE_0370"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0370"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.367"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="193" mass="20728" checksum="E97164E6755A052E" modified="2016-02-17" version="1">MPSDTLTRAALLGVLNCSDGASRAKSQSCLGELAQFPISDPDVRDTVLAHLAATRDPSRREQVIAAMTPTPLPADQLAPLLAQIRSLRTADEPYIRAAGLVHLAQWDRSAAIEQPLREGLDDADPEVVRSAITAVSVSNARSDELKQTLLLIASDSPPESELRDAAVAALRDFSFDAREYAIYRSAAARSRAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB55</accession>
    <name>A0A0S2DB55_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA polymerase sigma factor, ECF family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Sigma-70 family RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_02815</name>
        <name evidence="2" type="ORF">GLE_0404</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">C3</strain>
        </source>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="184" mass="20092" checksum="40427374C4E16F3A" modified="2016-02-17" version="1">MGEITVLLGQARAGDGAAWDRVVQLLYADLKRLARRASVGSGGQDVTALVHDCYLRLDRGGADGIESRAHFLSVAATAMRQLLINHARDRIADKRGGGQSHTTLGKADLDAARMAYSEAEEMVMIDAALKRLGDVDERLVRVLECRLFAGLSEEETALALGLPLRSSQRLWQQARERLRALLDA</sequence>
</entry>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <source>
            <dbReference type="EMBL" id="ALN55859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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        </source>
    </evidence>
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        <source>
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    </evidence>
    <sequence length="535" mass="57478" checksum="F2C1E2CA85E88B3B" modified="2016-02-17" version="1"> </sequence>
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    <accession>A0A0S2DBM2</accession>
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    <protein>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">YC36</strain>
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    </evidence>
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        <source>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
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                <person name="Kobayashi D.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
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    </reference>
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        <source>
            <dbReference type="EMBL" id="ALN55942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="53" mass="6441" checksum="234C4B91707EE64E" modified="2016-02-17" version="1">MPARTRDAFVQRIKQFPTQTKRVRGHRRESIIRGVFRWIFRFAHLRSRSIASD</sequence>
</entry>
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    <accession>A0A0S2DBX8</accession>
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            <authorList>
                <person name="Kobayashi D.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 3">C3</strain>
        </source>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="protein sequence ID" value="QCW24961.1"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009858">
        <property type="entry name" value="DUF1415"/>
    </dbReference>
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        <property type="entry name" value="DUF1415"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="185" mass="20701" checksum="F2BBC78338D3337B" modified="2016-02-17" version="1">MDERGPDPVAETVRWLERAVIGLNLCPFAKAVLAKRQIRFVLSHARTPEQLLEELSSELVLLEQTPAERIDTTLLIHPQALTDFLEFNDFLDLADEAVALLDLEGEIQIASFHPDYQFAGTAYDDIGNCTNRSPYPTLHLLRESSVERAVAAFPDPDAIVERNLATLEKLGAEGWRKLSAWNFSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC55</accession>
    <name>A0A0S2DC55_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0747</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56105">
        <property type="protein sequence ID" value="ALN56105"/>
        <property type="gene ID" value="GLE_0747"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0747"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.735"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="54" mass="5985" checksum="DA9B3963BD0D8BF4" modified="2016-02-17" version="1">MSRSRLAPLLQGLLRHSLEPVIPAKAGTHFDFAVASRRAAAEEQRQNGFRLSPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC63</accession>
    <name>A0A0S2DC63_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_24095</name>
        <name evidence="2" type="ORF">GLE_0756</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000090">
        <property type="protein sequence ID" value="OPD61354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946276.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000090.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0756"/>
    <dbReference type="EnsemblBacteria" id="ALN56114">
        <property type="protein sequence ID" value="ALN56114"/>
        <property type="gene ID" value="GLE_0756"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61354">
        <property type="protein sequence ID" value="OPD61354"/>
        <property type="gene ID" value="BV903_24095"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0756"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.744"/>
    <dbReference type="OMA" id="TTHPIAM"/>
    <dbReference type="OrthoDB" id="1232102at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016780">
        <property type="term" value="F:phosphotransferase activity, for other substituted phosphate groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="220" mass="22883" checksum="A79FF56035F4C14F" modified="2016-02-17" version="1">MSDPQASSRRAARYERRLALAAWLRARGATPNGLSLFAVGLSALAGAAFFFALRDPPHYGAALLLFAALCLGGRIACNRLDGVLARRGGMVGKAGEVYSDAPDRLADALVFLGAGYGLTPWLPWASDLGWAVSLLAVGTAYVRVLGLACGLREHGEGPMPRRTRMIAMAVAALLAAAGLALGQPAAVAWLLLAALAVVALGAALTIALRLRAIVRELESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCB7</accession>
    <name>A0A0S2DCB7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0761</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946281.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0761"/>
    <dbReference type="EnsemblBacteria" id="ALN56119">
        <property type="protein sequence ID" value="ALN56119"/>
        <property type="gene ID" value="GLE_0761"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0761"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.749"/>
    <dbReference type="OMA" id="FVTQCPH"/>
    <dbReference type="OrthoDB" id="1664216at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021834">
        <property type="entry name" value="DUF3426"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11906">
        <property type="entry name" value="DUF3426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="392" mass="40396" checksum="FCED3F5F4BF5FE00" modified="2016-02-17" version="1">MFLACPHCGYLVALIVAKDGPARACPRCGGSLQSEAPSAQEAASAVVAVAAPVPDALVSDASTPDASIAEPALHDAADAAPAAPQPAATPAPAPVRDEISLSLRRAPSAAPVRNETANPAQTGSIAPASGEDRDDAGAGDDASDPTPPAAPHAAETQARAPAAAPPQPATDASENDAANPTDAPAAAPARALPPLTATPIAATPARSRRQHKSETTVTSARRAPSFARQQARAQAPKPRAHWSGPAAIVALTLALALQLLLAQRAELAADARWRPLVSGLCGALGCTIPPWREPSALTMLNRNVLPVPERAGALRASAGFRNDARWPQPWPTLVLSLEDVDGRRVGQRAFAPGEYRRDHRPGELIAPGQSAAVQFEVLEPAPRVVAFTFDFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCP4</accession>
    <name>A0A0S2DCP4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0926</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56284">
        <property type="protein sequence ID" value="ALN56284"/>
        <property type="gene ID" value="GLE_0926"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0926"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.914"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="134" mass="14678" checksum="088EFA6748A10878" modified="2016-02-17" version="1">MLLWQGLQPRCFPFRSPRPDRKASGLKPLPPQRPLPQKPSLVSGAFAGGYGATNRPLRQAATPPAYPSAAQRIDVAPRRPLPPRPANPAATSRQPGGRILTGGRLPRPRRRNDPSRQARRRDQSPSLGSECVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCT4</accession>
    <name>A0A0S2DCT4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">ATP-dependent DNA helicase RecG</fullName>
            <ecNumber evidence="3 6">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">recG</name>
        <name evidence="9" type="ORF">GLE_0921</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the helicase family. RecG subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3 6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0921"/>
    <dbReference type="EnsemblBacteria" id="ALN56279">
        <property type="protein sequence ID" value="ALN56279"/>
        <property type="gene ID" value="GLE_0921"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0921"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.909"/>
    <dbReference type="OMA" id="DNGFQAC"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004609">
        <property type="entry name" value="ATP-dep_DNA_helicase_RecG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045562">
        <property type="entry name" value="RecG_dom3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033454">
        <property type="entry name" value="RecG_wedge"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19833">
        <property type="entry name" value="RecG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17191">
        <property type="entry name" value="RecG_wedge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00643">
        <property type="entry name" value="recG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="275"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="467"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="689" mass="75389" checksum="93E00EDA709D8E65" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCZ0</accession>
    <name>A0A0S2DCZ0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PepSY domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">PepSY-associated TM helix</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_05840</name>
        <name evidence="2" type="ORF">GLE_1051</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946489.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1051"/>
    <dbReference type="EnsemblBacteria" id="ALN56409">
        <property type="protein sequence ID" value="ALN56409"/>
        <property type="gene ID" value="GLE_1051"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1051"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1040"/>
    <dbReference type="OMA" id="HRGRFFG"/>
    <dbReference type="OrthoDB" id="1656356at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005625">
        <property type="entry name" value="PepSY-ass_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34219">
        <property type="entry name" value="PTHR34219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03929">
        <property type="entry name" value="PepSY_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="344"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="373" mass="41267" checksum="3AD857320A5C4235" modified="2016-02-17" version="1">MNSSQAALAPHAPAPRRLRAALKWLHLWLGLTLGTAFALVALSGTVLAFQRELALWAYPQLQRDADIAPQQRARALERIVAHWQAQGMTSLDLPSPQFPVWQGYFPNNERRYFDPASGELLLTRNTGNDLILWLRDWHTHLLAGKSGEQVLGAVGIAAVFLLLSGLYLWWPRWSALAASLKWYRGPPTRRWFSWHRGLGLWLLPLTLLAAITGTAMVYDEIARSALRAAFSEAEPAKPPKLAARADAPIDWAATLRAADAAVAADGPIPGAQLRRIGLPKKDSGLVTIRARAVDEWHPVGRSMIWIDPWRGALLGARDATRQGPGARAYEAMYPLHGGFVGGRAWQLLIALTGLAPPLLLVTGFLFWRRRRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD91</accession>
    <name>A0A0S2DD91_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycine cleavage system H protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">gcvH</name>
        <name evidence="7" type="ORF">BV903_03930</name>
        <name evidence="8" type="ORF">FE772_05940</name>
        <name evidence="6" type="ORF">GLE_1074</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">C3</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="3">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GcvH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000007">
        <property type="protein sequence ID" value="OPD65250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946506.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1074"/>
    <dbReference type="EnsemblBacteria" id="ALN56432">
        <property type="protein sequence ID" value="ALN56432"/>
        <property type="gene ID" value="GLE_1074"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65250">
        <property type="protein sequence ID" value="OPD65250"/>
        <property type="gene ID" value="BV903_03930"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1074"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1062"/>
    <dbReference type="OMA" id="YRDSHEW"/>
    <dbReference type="OrthoDB" id="1773485at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06848">
        <property type="entry name" value="GCS_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00272">
        <property type="entry name" value="GcvH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002930">
        <property type="entry name" value="GCV_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033753">
        <property type="entry name" value="GCV_H/Fam206"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017453">
        <property type="entry name" value="GCV_H_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11715">
        <property type="entry name" value="PTHR11715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01597">
        <property type="entry name" value="GCV_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00527">
        <property type="entry name" value="gcvH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="5">
        <location>
            <begin position="24"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-lipoyllysine" evidence="3 4">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR617453-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN56432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD65250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW25268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="131" mass="14150" checksum="54FE1C609EC43A98" modified="2016-02-17" version="1">MSEIPGDLKFMKSHEWARVEGDGKVTVGISDHAQGLLGDLVYVELPNVGDRVEAGNASAVVESVKAASDVYAPVSGTVTAVNTELSDKPETINEDAYGEGWIYTVEIDEPDQLNELLSPDDYAELLEDDDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDD7</accession>
    <name>A0A0S2DDD7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1200"/>
    <dbReference type="EnsemblBacteria" id="ALN56558">
        <property type="protein sequence ID" value="ALN56558"/>
        <property type="gene ID" value="GLE_1200"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1200"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1185"/>
    <dbReference type="OMA" id="TVLWFAK"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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            <begin position="1"/>
            <end position="28"/>
        </location>
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        <location>
            <begin position="29"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="230" mass="24644" checksum="42767D1FD419DA53" modified="2016-02-17" version="1">MMTMKSTNFFRMAALAGALAAFSAPALAVKPFSADYSASYMGMQGAGRMTVSQADGSRWKYELSITSPLAELRQTTTFDEAGGKLRPLSGSDSSKVLTKKKSVNASYDWSRGVATWTGDIKPDRSGPIKLQSGDLDGLLVNLAIVRDAAAGKPMSYRMVEDGRIKELSYTVVGKEAITVGGKSQQATKVSSKNGDKETIAWVVADVPVPVRILQRENGSDAIDLRVQAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDE4</accession>
    <name>A0A0S2DDE4_LYSEN</name>
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            <fullName evidence="5">Polyisoprenoid-binding protein</fullName>
        </submittedName>
        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_06230</name>
        <name evidence="4" type="ORF">GLE_1141</name>
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    <reference evidence="4 6" key="1">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ALN56499">
        <property type="protein sequence ID" value="ALN56499"/>
        <property type="gene ID" value="GLE_1141"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1141"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1126"/>
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    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007372">
        <property type="entry name" value="Lipid/polyisoprenoid-bd_YceI"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242187" evidence="2">
        <location>
            <begin position="24"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="YceI" evidence="3">
        <location>
            <begin position="70"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="37"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="291" mass="30031" checksum="C30ABD5B72F1A88A" modified="2016-02-17" version="1">MSLNRPCAIVLAALAALAGAASAAPAGAQQAVAAPADARQPAATPAAQPTAAATDAQTKTAPAAKSDPGTYGFDPVHTRVMFALSHAGFSQAIGTVSGAAGTLRFDPADWRGARLDVQVPLTRLDLGDGKWNKAALARNLLDGKRWPSARFVSERIEPAAGDPQRFQVCGTLSLHGVDGPLCLQVRFNQLKRHPLPPFHRTAGFSATATLSRAAFGIDAWKSVIGDEVELRIEAEAVRDKYVGDSPQGAADAAAGADAAPDSDSDSDPDSVRPDPAPPAPANAQPEPEPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDU8</accession>
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        <submittedName>
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        <submittedName>
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        </submittedName>
    </protein>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="gene ID" value="GLE_1146"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1146"/>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="44"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="101" mass="11011" checksum="C0E946A0E7297D88" modified="2016-02-17" version="1">MPIGNLFAGADAPAEGERFEALLTHKNLVIERIVSSARIQPTPYVQPQDEWVALLRGEAELDVAGETTILRAGDYLFLPAGTPHTVRKVAEGSVWLAVHLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE06</accession>
    <name>A0A0S2DE06_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glyoxalase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_07480</name>
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    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW25527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1415"/>
    <dbReference type="EnsemblBacteria" id="ALN56772">
        <property type="protein sequence ID" value="ALN56772"/>
        <property type="gene ID" value="GLE_1415"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1415"/>
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    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="6"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="141" mass="15568" checksum="48A00D7162D076C8" modified="2016-02-17" version="1">MNALAGSTIIPCLRYRDAHAAIDWLCRAFGFEKHAVYADGAIVHHAQLTYGPGMIMLGSVDPDNESEWSRRIVQPDEIGGRETQACCVLVGDADEHAARARAAGAQIVVDVADQDYGGRAYTCRDLEGRLWWFGTYNPWNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE10</accession>
    <name>A0A0S2DE10_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56707">
        <property type="protein sequence ID" value="ALN56707"/>
        <property type="gene ID" value="GLE_1350"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1350"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1332"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="37" mass="4501" checksum="CC07631994AC4F96" modified="2016-02-17" version="1">MPWKALVKATTFWXXXXXXXDLSWLRIRGRGLRRSYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE53</accession>
    <name>A0A0S2DE53_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fatty acid desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_1395</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1395"/>
    <dbReference type="EnsemblBacteria" id="ALN56752">
        <property type="protein sequence ID" value="ALN56752"/>
        <property type="gene ID" value="GLE_1395"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1395"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1377"/>
    <dbReference type="OMA" id="DMRDWAQ"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Acyl-CoA_DS"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="71"/>
            <end position="104"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN56752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="357" mass="39730" checksum="5F9767998F151341" modified="2016-02-17" version="1">MNPLPVNPWPAAKAVSATAASAKATPSAPAPQHAIPASLSAHRVRSRNRLADSVRSVSDGLVAWEPVRSLWFAAMAAGAIVGGALTFSWGAFALFVVSTAAVLLLGHSLGMHRKLIHDSFACAKWLEYLLVYCGVQVGLAGPLALVRTHDLRDYAQRLPHCHDYLAHRRGFLQDAWWQLHCELRLRAPPKIEIEARIADDRFYRFLQRTWMWQHLPWALGFYALGGWGWVFWGVCARVSAGVFGHWLVGYFAHNHGGMRHEVRGAAVQGRNVRFASLLTMGECWHNNHHAFPGSARLGLYPGEWDPGWWLLRALECVGLVRDLRLPEDLPPREELHCLDAAPPRASVPVSLQSIPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE84</accession>
    <name>A0A0S2DE84_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione-dependent formaldehyde-activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BV903_21895</name>
        <name evidence="6" type="ORF">FE772_08035</name>
        <name evidence="4" type="ORF">GLE_1535</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">C3</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD61829.1"/>
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    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946857.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000072.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1535"/>
    <dbReference type="EnsemblBacteria" id="ALN56892">
        <property type="protein sequence ID" value="ALN56892"/>
        <property type="gene ID" value="GLE_1535"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61829">
        <property type="protein sequence ID" value="OPD61829"/>
        <property type="gene ID" value="BV903_21895"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1535"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1517"/>
    <dbReference type="OMA" id="ACDCDFC"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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            <begin position="3"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD61829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW25622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="142" mass="15550" checksum="E963A7A7417124BD" modified="2016-02-17" version="1">MRIDGACHCGNIRFVLDWRDEPDAIAARACDCTFCVKHGGVWTGRAEAALRLSLRDPQRVSRYAFGTGTADFLVCAHCGAVPAVVSRIEGRLYAVVNVNTFEGFDPARIQRAPASLDGETESARLARRQRNWIGEVEIVEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEF4</accession>
    <name>A0A0S2DEF4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_07990</name>
        <name evidence="3" type="ORF">GLE_1525</name>
    </gene>
    <organism evidence="3 5">
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        <lineage>
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            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_1525"/>
    <dbReference type="EnsemblBacteria" id="ALN56882">
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        <property type="gene ID" value="GLE_1525"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
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    </dbReference>
    <proteinExistence type="predicted"/>
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            <begin position="1"/>
            <end position="22"/>
        </location>
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            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="178" mass="19370" checksum="3356D516540B5E70" modified="2016-02-17" version="1">MRPFKLASVLLALLVLSFAAQARKPYVEIERRLTPQQLQEVGLSEEQLAKLNRMLRDADASEGAAPGVAAAAPAEAEADDAGPQVGAGAPRERSPGAGQFIGLNDEPIKSRLKHDVAGWEPGTVFELENGQQWKVLKGRMSLKKPIPKPEIVVVPGVAGRWFLQVDEDMPKARVYRID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEM2</accession>
    <name>A0A0S2DEM2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1613</name>
    </gene>
    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="47" mass="5399" checksum="22370BC0F4D32683" modified="2016-02-17" version="1">MTQTLFSQADSHAARTWKNVQSITKFQAEPAKRRHRREDGGIEPFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF40</accession>
    <name>A0A0S2DF40_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dipeptidyl carboxydipeptidase family</fullName>
            <ecNumber evidence="3">3.4.15.-</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="4">M2 family metallopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_08185</name>
        <name evidence="3" type="ORF">GLE_1570</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.15.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW25650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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            <begin position="1"/>
            <end position="20"/>
        </location>
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        <location>
            <begin position="21"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="654"/>
            <end position="675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25650.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="675" mass="74698" checksum="2CC0869A229DB67E" modified="2016-02-17" version="1"> </sequence>
</entry>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
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    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN57301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="670" mass="71945" checksum="AC973489E5655835" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFG7</accession>
    <name>A0A0S2DFG7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-ethylammeline chlorohydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">TRZ/ATZ family hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_09310</name>
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    </gene>
    <organism evidence="2 4">
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        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN57168">
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        <property type="gene ID" value="GLE_1816"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1816"/>
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    <dbReference type="OMA" id="FCPVERL"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
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        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="67"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW25829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="446" mass="48335" checksum="4CE2AD7647118E32" modified="2016-02-17" version="1">MTSELQPVPCDLSIEAGWVVPVEPHAVVLEHHAVIVDKGVIADVLPIAQARQRYAPAQTVSRPESALIPGLVNAHTHNPMTLLRGIADDLPLMEWLQGHIWPVEAAVIGPQFVEDGIALSIAEMLRGGTTCANENYFFPDVQAAVYKRHGFRARVGLPVIDFPTAWAKTSDEYFDRAGEVHDLWRDDALVATAFAPHAPYTVSDANFERIRMLADQLDLPIHLHTHETAQEIADSIKQYGQRPLARLDRLGLVSDRLIAVHMTQLTDAEIELCAQRGVSVVHCPESNLKLASGFCPACKLHHAGVNLAIGTDGCASNNDLDMFGETRTAAILAKAVANDAKALDAFSALRAATLGGAKALGFDAKIGSIEVGKQADLVCVDLGQLETQPVHHVVSQLIYATGRHQVGDVWIAGKAKLRERVLVDMDAAALVANARQWRERIAAIAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFJ9</accession>
    <name>A0A0S2DFJ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_10830</name>
        <name evidence="4" type="ORF">FE772_09945</name>
        <name evidence="2" type="ORF">GLE_1957</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000025">
        <property type="protein sequence ID" value="OPD63892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947168.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1957"/>
    <dbReference type="EnsemblBacteria" id="ALN57308">
        <property type="protein sequence ID" value="ALN57308"/>
        <property type="gene ID" value="GLE_1957"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63892">
        <property type="protein sequence ID" value="OPD63892"/>
        <property type="gene ID" value="BV903_10830"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1957"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1922"/>
    <dbReference type="OMA" id="WVVLKKQ"/>
    <dbReference type="OrthoDB" id="2003644at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="80" mass="8329" checksum="6BE023303F5B73CB" modified="2016-02-17" version="1">MSAGLFAQYVAIAIAVLVSAIVVARKQFPGAVRRLRIACALPLVREGRPPWLRSLGKRIAPPARASGPNCGGCDSCGPSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFN2</accession>
    <name>A0A0S2DFN2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF2974 domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Lipase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_10110</name>
        <name evidence="2" type="ORF">GLE_1988</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57338">
        <property type="protein sequence ID" value="ALN57338"/>
        <property type="gene ID" value="GLE_1988"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1988"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1955"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024499">
        <property type="entry name" value="Mbeg1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11187">
        <property type="entry name" value="DUF2974"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242659" evidence="1">
        <location>
            <begin position="20"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="328" mass="36418" checksum="67244870C8B5FC32" modified="2016-02-17" version="1">MMRILSAIAFLLLCGCSTAPLRVADRVEPSPHVLVRPYVPQLNESGLFHLSCTDRYPNGNSVYAAFDLDTADVGRVALARRHFVHAAMANNAYMDPAKKPVFRLPGWTLHDSLISDTGLALQVYGDGGYLVTSANIVVAYRGTDFGSPIDWLNNFSVVEPPQYRQAYAHLKGLRMRYPNARITAVGHSLGGGIAMNMSLRLDGVDAVAFNMSPRVRFGATHAPDVYRASIFEVGEILTGATRFYAAVMLPRDTHYGNYNFLDYRYFTFSPVPEHGIYELTRALTLVAMMRGSKEAREFFRVNIGEAQARSVDWEHCQPIFDTHSANVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFW6</accession>
    <name>A0A0S2DFW6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1815</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57167">
        <property type="protein sequence ID" value="ALN57167"/>
        <property type="gene ID" value="GLE_1815"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1815"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1786"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="44" mass="4860" checksum="CCF03EA4E5AC2194" modified="2016-02-17" version="1">MLLRLFLPLSFPGKKSDGKMDSGFRRNDGFEGARFRGGAAELRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGH4</accession>
    <name>A0A0S2DGH4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-N-acetylhexosaminidase</fullName>
            <ecNumber evidence="3">3.2.1.52</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Beta-N-acetylhexosaminidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">N-acetyl-beta-glucosaminidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLE_2271</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 20 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947413.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2271"/>
    <dbReference type="EnsemblBacteria" id="ALN57620">
        <property type="protein sequence ID" value="ALN57620"/>
        <property type="gene ID" value="GLE_2271"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2271"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2236"/>
    <dbReference type="OMA" id="DECPKTA"/>
    <dbReference type="OrthoDB" id="727559at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004563">
        <property type="term" value="F:beta-N-acetylhexosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102148">
        <property type="term" value="F:N-acetyl-beta-D-galactosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025705">
        <property type="entry name" value="Beta_hexosaminidase_sua/sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015883">
        <property type="entry name" value="Glyco_hydro_20_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015882">
        <property type="entry name" value="HEX_bac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011658">
        <property type="entry name" value="PA14_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600">
        <property type="entry name" value="PTHR22600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00728">
        <property type="entry name" value="Glyco_hydro_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02838">
        <property type="entry name" value="Glyco_hydro_20b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07691">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00738">
        <property type="entry name" value="GLHYDRLASE20"/>
    </dbReference>
    <dbReference type="SMART" id="SM00758">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="SSF55545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PA14" evidence="8">
        <location>
            <begin position="668"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="792"/>
            <end position="813"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN57620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="813" mass="89778" checksum="BDA69F39B265E1F9" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGL9</accession>
    <name>A0A0S2DGL9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2407</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2407"/>
    <dbReference type="EnsemblBacteria" id="ALN57756">
        <property type="protein sequence ID" value="ALN57756"/>
        <property type="gene ID" value="GLE_2407"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2407"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2369"/>
    <dbReference type="OMA" id="FCCIGTT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="224" mass="23977" checksum="580062F86BBFD0EC" modified="2016-02-17" version="1">MIGARTRRDGRGRRPMRLLLAGATGLVGSHALRLALADPMIERVIAPTRRALPPHPKLEAPRVDWDALPADAPWWRVDAAVCALGTTMRAAGSREAFRKVDFDYPLAIARAAHRAGARAYALNSALGADAGSRVFYNRVKGELEQALAGVGFDSLTYVRPGLIGGERQQSRPGEAAATVLLRALAPALPRRWRINPAPRIAQALLDAALQAAPGVHAVGSERLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGP1</accession>
    <name>A0A0S2DGP1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter, permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_2340</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2340"/>
    <dbReference type="EnsemblBacteria" id="ALN57689">
        <property type="protein sequence ID" value="ALN57689"/>
        <property type="gene ID" value="GLE_2340"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2340"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2302"/>
    <dbReference type="OMA" id="FPMFVWG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="61"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="271" mass="29092" checksum="4EB955515929CB10" modified="2016-02-17" version="1">MKRRPFALYTLMALGYAFLYLPIVSVIVYSFSGSDRATTWGGFSLQWYAALARNEQILEAAQRSLIIAAISATAAVALGTASGLALSRFGKFPGRGILSLMNSAPMVMPDVMLGLSSLLLFVGLQQLFGWPERGMTTITLAHITLTACYVTVVVRSRMTSMDASLEEAAMDLGAKPWRVFFVITLPLIAPALLAGWLLAFTLSLDDLVIASFASGPGSTTLPMLVYSKVKLGVTPEINALTTIIVVLVAIGVSVAGVLMHRRERKLARSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGT4</accession>
    <name>A0A0S2DGT4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PF03932 family protein CutC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 3" type="primary">cutC</name>
        <name evidence="3" type="ORF">GLE_2265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the CutC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947410.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2265"/>
    <dbReference type="EnsemblBacteria" id="ALN57614">
        <property type="protein sequence ID" value="ALN57614"/>
        <property type="gene ID" value="GLE_2265"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2265"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2230"/>
    <dbReference type="OMA" id="FHRAFDQ"/>
    <dbReference type="OrthoDB" id="1728422at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00795">
        <property type="entry name" value="CutC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005627">
        <property type="entry name" value="Cu_homeostasis_CutC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036822">
        <property type="entry name" value="CutC_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12598">
        <property type="entry name" value="PTHR12598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03932">
        <property type="entry name" value="CutC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110395">
        <property type="entry name" value="SSF110395"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="245" mass="25315" checksum="405FBD53DAA12510" modified="2016-02-17" version="1">MNATDRPLLEISAGSLASALAAQEGGADRVELCDNLAEGGTTPSYGALAVARDRLRIPLYVLIRPRGGDFLYDPAERAAMLADVEACVRLGCDGVVIGALDADGEVDAAVCGELIAAAGPLGVTFHRAFDAVRDAQRALEAVIALGCERILTSGGAADADTGAARIAQWGAQSAGRIALMAGAGVTPENIADVARRAGVRELHASAKAPRRSAMRYRNDALAGLSPDWSQSDAQRVRALVRALRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHF8</accession>
    <name>A0A0S2DHF8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CheR-type methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2451</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947547.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2451"/>
    <dbReference type="EnsemblBacteria" id="ALN57800">
        <property type="protein sequence ID" value="ALN57800"/>
        <property type="gene ID" value="GLE_2451"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2451"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2414"/>
    <dbReference type="OMA" id="ETFFFRY"/>
    <dbReference type="OrthoDB" id="1378151at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022642">
        <property type="entry name" value="CheR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000780">
        <property type="entry name" value="CheR_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01739">
        <property type="entry name" value="CheR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00996">
        <property type="entry name" value="CHERMTFRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00138">
        <property type="entry name" value="MeTrc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50123">
        <property type="entry name" value="CHER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CheR-type methyltransferase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="352"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="420" mass="45055" checksum="2DFDBD0CD689F7C8" modified="2016-02-17" version="1">MDAAAFKRWLKATMGLDAEAVGPGVVERAIAGRMRALGVAEADAYWRRLQAQPLEQQELIEAVVVPETWFFRGVEAFDALALAFASRLSEPGNAPLRLLSLPCSTGEEPYTLAMALLDAGWPPQRLRIDAYDISERALAKAGHAVYGANSFRGGDLRYRDRHFRALGHGRWQLSDAVRGCVRLHRANVLAIDFLPEAASFDAVFCRNLLIYFDQDTQVRAVGVLARALAAGGLLFVGAAETGLLLSLGYASAQIPMAAAFRNQRSAPVPAPAPQQPWRAPALAPLPAAAARPRPFAAVATALAARPAPASPPAPAQAADDSLPQARRLADNGDFAQAERLCQAHLRAHGPNAEALCLLGVIYGADGADARAEDAFRKALYLQPDHAESLMHLALLLDAKGDAAGARLMRQRAARHRDRNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHG9</accession>
    <name>A0A0S2DHG9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF4097 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_13575</name>
        <name evidence="3" type="ORF">GLE_2711</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947757.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2711"/>
    <dbReference type="EnsemblBacteria" id="ALN58059">
        <property type="protein sequence ID" value="ALN58059"/>
        <property type="gene ID" value="GLE_2711"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2711"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2670"/>
    <dbReference type="OMA" id="FDKIDGP"/>
    <dbReference type="OrthoDB" id="1714996at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025164">
        <property type="entry name" value="DUF4097"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13349">
        <property type="entry name" value="DUF4097"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242567" evidence="1">
        <location>
            <begin position="26"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4097" evidence="2">
        <location>
            <begin position="88"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="259" mass="26649" checksum="2481804AAB483CAD" modified="2016-02-17" version="1">MRFPPSARPLLALLCAALLPGAAFAADRCDNAQPRNLALDLRGVEAVVFEIGSDDLIVEGGNGAPAVAGHACASNPADLAGLTLSQRREGNKLVVTAEHAKRFGLNFNGQRYMRLHASVPQNLRVQLKVGSGDASVRNVAALSADVNSGDIAIENVRGLTVASVGSGDIVLRDIGPLQIVSLGSGDLKARNVGGDVRIGTVGSGDVELDQVAGSVTLDRIGSGDLEVDGVRGDLRVARVGSGSVKHRGVSGRVDVPKQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHL8</accession>
    <name>A0A0S2DHL8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58198">
        <property type="protein sequence ID" value="ALN58198"/>
        <property type="gene ID" value="GLE_2850"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2850"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2812"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594799" evidence="2">
        <location>
            <begin position="21"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="54" mass="5432" checksum="0A2B1026C3B4DCE1" modified="2016-02-17" version="1">MLTAAAIRCTVALWPVVAAAASAGEPGGGEAPPHRDPQDEATAAAEPIEPRRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHQ1</accession>
    <name>A0A0S2DHQ1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Asparagine--tRNA ligase</fullName>
            <ecNumber evidence="5">6.1.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Asparaginyl-tRNA synthetase</fullName>
            <shortName evidence="5">AsnRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">asnS</name>
        <name evidence="8" type="ORF">FE772_13310</name>
        <name evidence="7" type="ORF">GLE_2656</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + L-asparagine + tRNA(Asn) = AMP + diphosphate + H(+) + L-asparaginyl-tRNA(Asn)</text>
            <dbReference type="Rhea" id="RHEA:11180"/>
            <dbReference type="Rhea" id="RHEA-COMP:9659"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.22"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.22" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947708.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2656"/>
    <dbReference type="EnsemblBacteria" id="ALN58004">
        <property type="protein sequence ID" value="ALN58004"/>
        <property type="gene ID" value="GLE_2656"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2656"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2615"/>
    <dbReference type="OMA" id="DNMDLAE"/>
    <dbReference type="OrthoDB" id="1138123at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004816">
        <property type="term" value="F:asparagine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006421">
        <property type="term" value="P:asparaginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00534">
        <property type="entry name" value="Asn_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004522">
        <property type="entry name" value="Asn-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00457">
        <property type="entry name" value="asnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 5 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="6">
        <location>
            <begin position="139"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW26496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="466" mass="52143" checksum="95475B6B25C014D1" modified="2016-02-17" version="1">MTVVSVEQALAGKIPAGGEVTVRGWVRTRRDSKAGLSFVNVSDGSCFAPIQVVATNELGNYDSEIKHLSSGCSVIATGTLVASQGQGQSFEIQASSVEVVGWVEDPLTYPMQPKQHSLEYLREFAHLRPRTNLFGAVTRIRHCLSQAVHRYFHENGYYWISTPIVTTSDAEGAGQMFRVSTLDLANLPRGKDGAVDFSRDFFGKETFLTVSGQLNVEAYCLALSKVYTFGPTFRAENSNTTRHLAEFWMIEPEIAFADLMENAQVAEDFLKYLFRAVLDERADDMAFIAERVQPDAIKRLEAFVNSPFERIDYTDAIALLQKSGKKFEFPVEWGLDLQTEHERWLTEEHVGRPVVVLNYPEHFKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDARMAQFGLDPAHYGWYRDFRRYGTVPHAGFGLGFERLVVYVCGLANIRDAIAYPRAPGSAEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHQ6</accession>
    <name>A0A0S2DHQ6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidoglycan glycosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">pbpC</name>
        <name evidence="14" type="ORF">GLE_2737</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the transpeptidase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the glycosyltransferase 51 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.129" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2737"/>
    <dbReference type="EnsemblBacteria" id="ALN58085">
        <property type="protein sequence ID" value="ALN58085"/>
        <property type="gene ID" value="GLE_2737"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2737"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2695"/>
    <dbReference type="OMA" id="APENFDM"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001264">
        <property type="entry name" value="Glyco_trans_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011815">
        <property type="entry name" value="PBP_1c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009647">
        <property type="entry name" value="PBP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036950">
        <property type="entry name" value="PBP_transglycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06832">
        <property type="entry name" value="BiPBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00912">
        <property type="entry name" value="Transgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02073">
        <property type="entry name" value="PBP_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="7 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Transgly" evidence="12">
        <location>
            <begin position="64"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="11">
        <location>
            <begin position="322"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="BiPBP_C" evidence="13">
        <location>
            <begin position="708"/>
            <end position="795"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF06832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN58085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="799" mass="87053" checksum="B01D1EED83E9DB7F" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHS1</accession>
    <name>A0A0S2DHS1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycine zipper 2TM domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Surface antigen family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">D9T17_15305</name>
        <name evidence="4" type="ORF">FE772_13235</name>
        <name evidence="3" type="ORF">GLE_2639</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000037">
        <property type="protein sequence ID" value="ROU06061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2639"/>
    <dbReference type="EnsemblBacteria" id="ALN57987">
        <property type="protein sequence ID" value="ALN57987"/>
        <property type="gene ID" value="GLE_2639"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2639"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2598"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008816">
        <property type="entry name" value="Gly_zipper_2TM_dom"/>
    </dbReference>
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        <property type="entry name" value="Rick_17kDa_Anti"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726728" evidence="1">
        <location>
            <begin position="26"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="Rick_17kDa_Anti" evidence="2">
        <location>
            <begin position="54"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU06061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="110" mass="11326" checksum="B07FF000DAA53EF5" modified="2016-02-17" version="1">MNSTFKTMIAAALVSCVMVTGAAGAQTKSKKTPHCYNVEVQRPKQIKDQHKIAGTAIGAVAGGLLGNQVGGGNGKKLATAAGAVGGAFAGRKIQENQQNKTETVIERRCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHS4</accession>
    <name>A0A0S2DHS4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">HAMP domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Methyl-accepting chemotaxis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mcpC</name>
        <name evidence="4" type="ORF">FE772_14405</name>
        <name evidence="3" type="ORF">GLE_2883</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW26666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947881.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2883"/>
    <dbReference type="EnsemblBacteria" id="ALN58231">
        <property type="protein sequence ID" value="ALN58231"/>
        <property type="gene ID" value="GLE_2883"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2883"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2845"/>
    <dbReference type="OMA" id="KNKLRFQ"/>
    <dbReference type="OrthoDB" id="429006at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033462">
        <property type="entry name" value="Cache_3-Cache_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029151">
        <property type="entry name" value="Sensor-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17201">
        <property type="entry name" value="Cache_3-Cache_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="295"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="2">
        <location>
            <begin position="318"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="378" mass="41177" checksum="A908AC1A08DF5D9B" modified="2016-02-17" version="1">MFLHSLRVRLLLPVLALVLVAVLALTVVLAIAQARHVRADAAQSIERRTLALQSLFGVTRSIMLDRTHDAMRLLRSEGRKLGAASLGGRVTVGGRASNDLVLGSVSQANNFALVDSVTAIAQGTATLFARDGEDFVRVATNVRKDDGSRAIGTQLDPLGQVIPHMRKGENFYGVVDILGTPYVTGYEPIFADSDARRAIGVWYVGYKTDLQALSEVVDASQVLDSGFIAVFDSKDKLRFHSKTGATVDPAQIARIAQETPDGWVVSREEVPNWGFTLVSAYPKSDVDKAIVRQSLWIGGIGLLVCALILGLQWGLIWSRVLKPIQHLTTVAEELSVGKWGHTIEETELKDEIGKLARAISRLSYSVRVAMERLAKLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHX2</accession>
    <name>A0A0S2DHX2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Segregation and condensation protein A</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Segregation/condensation protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">scpA</name>
        <name evidence="4" type="ORF">BV903_06095</name>
        <name evidence="5" type="ORF">FE772_13930</name>
        <name evidence="3" type="ORF">GLE_2790</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000011">
        <property type="protein sequence ID" value="OPD64780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947815.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000011.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2790"/>
    <dbReference type="EnsemblBacteria" id="ALN58138">
        <property type="protein sequence ID" value="ALN58138"/>
        <property type="gene ID" value="GLE_2790"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64780">
        <property type="protein sequence ID" value="OPD64780"/>
        <property type="gene ID" value="BV903_06095"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2790"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2746"/>
    <dbReference type="OMA" id="YLVMAAM"/>
    <dbReference type="OrthoDB" id="959677at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01805">
        <property type="entry name" value="ScpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003768">
        <property type="entry name" value="ScpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33969">
        <property type="entry name" value="PTHR33969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02616">
        <property type="entry name" value="SMC_ScpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD64780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="317" mass="35366" checksum="1EEBF28EABEF8ED5" modified="2016-02-17" version="1">MTNQAAPADESAADSTAESVAGPKPGQVPGPTAPQQQEMPLAVVHGQPVLQIPQDLYIPPDALEVILEAFEGPLDLLLYLIRRQNLDILDIPVADITRQYVEYIQAMHEMRFELAADYLVMAAMLAEIKSRMLLPRAVNEEGEEEDPRAELVRRLQEYERYKKAAEDIDALPRQDRDTAPVQAFVPDRAAVRLPPPVELKELLLALHDVFKRAELYTQHAIKRDALSVRQRMGELLARMSDGAFYRFESLFTVEEGRLGAVVTFLGLLTLAKEQLVEIVQDAPLAPIYAKSLALMKDPDEIELSSEFDSAANDEDPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHX8</accession>
    <name>A0A0S2DHX8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">5'-nucleotidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2686</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947735.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2686"/>
    <dbReference type="EnsemblBacteria" id="ALN58034">
        <property type="protein sequence ID" value="ALN58034"/>
        <property type="gene ID" value="GLE_2686"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2686"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2645"/>
    <dbReference type="OMA" id="IRTLMAW"/>
    <dbReference type="OrthoDB" id="880166at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008253">
        <property type="term" value="F:5'-nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010394">
        <property type="entry name" value="5-nucleotidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31367">
        <property type="entry name" value="PTHR31367"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06189">
        <property type="entry name" value="5-nucleotidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="306" mass="32979" checksum="A1DDCF27F8360DB6" modified="2016-02-17" version="1">MPDRDADPLIVAISSRTLFDMEESHSLFEREGIDAYAAFQRAREDDVLRPGIAFPLVRKLLALNRDAPADAPRVEVILISRNSADSGLRIFNSIAHHGLSIKRAAFSNGAPPFPYIRPFGADLFLSANAQDVSAALEAGIAAATLLPAVPNAKLAPHLPADQLRIAFDGDAVIFDDEGERVSREGGLAAFAEHERNHAGEPLSGGPFRGFLDALHRLQAAFPVGQDAPIRTALVTARSVPAHERVIRTLREWDIRLDEALFLGGRAKGPFLEAFGADIFFDDSENNIASARGHVAAGHVPHGVANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIB4</accession>
    <name>A0A0S2DIB4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Succinate dehydrogenase iron-sulfur subunit</fullName>
            <ecNumber evidence="9">1.3.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">sdhB</name>
        <name evidence="14" type="ORF">BV903_14525</name>
        <name evidence="15" type="ORF">FE772_15210</name>
        <name evidence="13" type="ORF">GLE_3043</name>
    </gene>
    <organism evidence="13 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">C3</strain>
        </source>
    </reference>
    <reference evidence="14 17" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">B25</strain>
        </source>
    </reference>
    <reference evidence="15 18" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 18">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a menaquinone + succinate = a menaquinol + fumarate</text>
            <dbReference type="Rhea" id="RHEA:27834"/>
            <dbReference type="Rhea" id="RHEA-COMP:9537"/>
            <dbReference type="Rhea" id="RHEA-COMP:9539"/>
            <dbReference type="ChEBI" id="CHEBI:16374"/>
            <dbReference type="ChEBI" id="CHEBI:18151"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="EC" id="1.3.5.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a quinone + succinate = a quinol + fumarate</text>
            <dbReference type="Rhea" id="RHEA:40523"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a quinone + succinate = a quinol + fumarate</text>
            <dbReference type="Rhea" id="RHEA:40523"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="9">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
        <text evidence="9">Binds 1 [3Fe-4S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="9">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.1" evidence="9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000037">
        <property type="protein sequence ID" value="OPD63198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948001.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000037.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3043"/>
    <dbReference type="EnsemblBacteria" id="ALN58390">
        <property type="protein sequence ID" value="ALN58390"/>
        <property type="gene ID" value="GLE_3043"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63198">
        <property type="protein sequence ID" value="OPD63198"/>
        <property type="gene ID" value="BV903_14525"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3043"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3003"/>
    <dbReference type="OMA" id="DGQYFGP"/>
    <dbReference type="OrthoDB" id="1605514at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102040">
        <property type="term" value="F:fumarate reductase (menaquinone)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008177">
        <property type="term" value="F:succinate dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004489">
        <property type="entry name" value="Succ_DH/fum_Rdtase_Fe-S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025192">
        <property type="entry name" value="Succ_DH/fum_Rdtase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13085">
        <property type="entry name" value="Fer2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00384">
        <property type="entry name" value="dhsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="7 9" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5 9" id="KW-0408">Iron</keyword>
    <keyword evidence="6 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="11">
        <location>
            <begin position="29"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="12">
        <location>
            <begin position="163"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN58390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OPD63198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW26790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="262" mass="29708" checksum="9F963AE8F81A3DF9" modified="2016-02-17" version="1">MAQFSLPKNSKIQKGRHWATPGAKQPRTFKVYRWNPDDGMNPRVDTYEVDLASCGPMVLDALIKIKNEIDPTLTFRRSCREGICGSCAMNIDGTNTLACTRAIADCGDAKNDVPIYPLPHMDVVKDLVPDLTHFYAQYASIRPWLRTQSPTPSDRERLQSPADREKLDGLYECILCACCSTSCPSYWWNGDRYLGPAILLQAYRWIIDSRDEDTGARLDDLEDPFKLYRCHTIMNCARTCPKGLNPAQAIGEIKKLMLQRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIC6</accession>
    <name>A0A0S2DIC6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nuclear transport factor 2 family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Response regulator receiver domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_13950</name>
        <name evidence="2" type="ORF">GLE_2793</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947817.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58141">
        <property type="protein sequence ID" value="ALN58141"/>
        <property type="gene ID" value="GLE_2793"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2793"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2749"/>
    <dbReference type="OMA" id="VRFQYEC"/>
    <dbReference type="OrthoDB" id="1650155at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009783">
        <property type="entry name" value="DUF1348"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31757">
        <property type="entry name" value="PTHR31757"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07080">
        <property type="entry name" value="DUF1348"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="155" mass="18398" checksum="398717C5B2E84FC5" modified="2016-02-17" version="1">MEPRPPLPPFTRDTAAHKVRLAEDAWNSRDPERVAQAYSVDTHWRNRAEFVEGREAAAAFLRRKWSRELEYRLIKELWAHDGHRIAVRFAYEWRDDSGQWYRSYGNENWEFADDGRMARRIASINDRPIAASERKFHWPQGRRPDDHPGLSELGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DID5</accession>
    <name>A0A0S2DID5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TetR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">TetR/AcrR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_02690</name>
        <name evidence="6" type="ORF">D9T17_16620</name>
        <name evidence="5" type="ORF">FE772_14530</name>
        <name evidence="3" type="ORF">GLE_2912</name>
    </gene>
    <organism evidence="3 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">C3</strain>
        </source>
    </reference>
    <reference evidence="4 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">OH11</strain>
        </source>
    </reference>
    <reference evidence="5 10" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 10">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000005">
        <property type="protein sequence ID" value="OPD65443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000041">
        <property type="protein sequence ID" value="ROU05802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947903.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2912"/>
    <dbReference type="EnsemblBacteria" id="ALN58260">
        <property type="protein sequence ID" value="ALN58260"/>
        <property type="gene ID" value="GLE_2912"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65443">
        <property type="protein sequence ID" value="OPD65443"/>
        <property type="gene ID" value="BV903_02690"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2912"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2874"/>
    <dbReference type="OMA" id="TSMRQIT"/>
    <dbReference type="OrthoDB" id="2089619at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041586">
        <property type="entry name" value="PsrA_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17939">
        <property type="entry name" value="TetR_C_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="7"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD65443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROU05802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="206" mass="22710" checksum="0CA472304DCD8346" modified="2016-02-17" version="1">MSSTAHFSTKDRILGAAEELFAQFGFTGTSLRQVTSRADVNIAAVNYHFGSKENLVNEVFRRRMDEMTAQRLSALKAALAERPGELEPILAAFVEPALALAQDRNGGGAFVRVIARAYAEKNDSLRKFLSDHYGHVLREFAKAIATAVPGLSKEELYWRLDFLAGSLTYAMADFGLIKRPAGVTEQAHRERAARELIRFAAAGFKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIV8</accession>
    <name>A0A0S2DIV8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_15470</name>
        <name evidence="2" type="ORF">GLE_3105</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948046.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3105"/>
    <dbReference type="EnsemblBacteria" id="ALN58452">
        <property type="protein sequence ID" value="ALN58452"/>
        <property type="gene ID" value="GLE_3105"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3105"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3063"/>
    <dbReference type="OMA" id="LSIHHDQ"/>
    <dbReference type="OrthoDB" id="1872172at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045057">
        <property type="entry name" value="Gcn5-rel_NAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031165">
        <property type="entry name" value="GNAT_YJDJ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31435">
        <property type="entry name" value="PTHR31435"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14542">
        <property type="entry name" value="Acetyltransf_CG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51729">
        <property type="entry name" value="GNAT_YJDJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="91" mass="9899" checksum="247BB098669ED874" modified="2016-02-17" version="1">MPVTVTHDPAQQRFTTVVDGVEAELEYQLRGDQLVIAHTGVPEAIGGRGIAGDLVRAAFEYARQAGYKVRPACSYAAAWAERHPEYSQLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIY6</accession>
    <name>A0A0S2DIY6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ptpA</name>
        <name evidence="8" type="ORF">BV903_14465</name>
        <name evidence="7" type="ORF">GLE_3030</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">B25</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:10137"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:82620"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the low molecular weight phosphotyrosine protein phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000037">
        <property type="protein sequence ID" value="OPD63188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947991.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000037.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3030"/>
    <dbReference type="EnsemblBacteria" id="ALN58377">
        <property type="protein sequence ID" value="ALN58377"/>
        <property type="gene ID" value="GLE_3030"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63188">
        <property type="protein sequence ID" value="OPD63188"/>
        <property type="gene ID" value="BV903_14465"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3030"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2990"/>
    <dbReference type="OMA" id="TGSWHVG"/>
    <dbReference type="OrthoDB" id="2062716at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017867">
        <property type="entry name" value="Tyr_phospatase_low_mol_wt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00719">
        <property type="entry name" value="LMWPTPASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LMWPc" evidence="6">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD63188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="158" mass="17180" checksum="0E2AEB737F986193" modified="2016-02-17" version="1">MRLLVVCLGNICRSPVAEGVLRARIEASSLRGLIELDSAGTGDWHVGEPPDRRSIANAAQHGVDIAGLRARQLAAADYRECDWLLCADRANLRDVRARAPKDATAQSALLLDWCGTVADGEIPDPYTGGPAQFEHVFQLLDRAADGAIARLRRELQLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ18</accession>
    <name>A0A0S2DJ18_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">UPF0271 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948079.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3150"/>
    <dbReference type="EnsemblBacteria" id="ALN58496">
        <property type="protein sequence ID" value="ALN58496"/>
        <property type="gene ID" value="GLE_3150"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3150"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3107"/>
    <dbReference type="OMA" id="DRTYKQD"/>
    <dbReference type="OrthoDB" id="918580at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005501">
        <property type="entry name" value="LamB/YcsF/PxpA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30292">
        <property type="entry name" value="PTHR30292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03746">
        <property type="entry name" value="LamB_YcsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="247" mass="25924" checksum="CF958CDD52B07C36" modified="2016-02-17" version="1">MSGRIDFNCDLGEGCGDDAAILPYVTSANIACGGHAGDEASMRETLRLCRAHGVAAGAHPGYEDREHFGRRALALAHDEVVALVTRQFARLAAIADEEGVALTHLKPHGALYNLAADDRGVAEAIAGAVAQCDPRLIVFGLAQSELTNAAQRLGLRVAHEVFAERGYAANGRLLPRGQPGAVIESLDRAIAQVRELALHGRVRAADGETVAVRADTLCLHGDRSDAAQFARAVRAALEADGVRVAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJG7</accession>
    <name>A0A0S2DJG7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58626">
        <property type="protein sequence ID" value="ALN58626"/>
        <property type="gene ID" value="GLE_3280"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3280"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="50" mass="5832" checksum="71A3D2CA082A7F5C" modified="2016-02-17" version="1">MQHRTVHGGSCCEERWQRRQPPASAPRGETRPSASAPPWRERTKQHIRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJI2</accession>
    <name>A0A0S2DJI2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58686">
        <property type="protein sequence ID" value="ALN58686"/>
        <property type="gene ID" value="GLE_3340"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3340"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3290"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="39" mass="4517" checksum="C056108511AA5B50" modified="2016-02-17" version="1">MKCEVAPGRIASLRFACERMQGRSARLSYRLSARRMMAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJJ7</accession>
    <name>A0A0S2DJJ7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptidase, S54 (Rhomboid) family</fullName>
            <ecNumber evidence="7">3.4.21.-</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Rhomboid family intramembrane serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BV903_22060</name>
        <name evidence="9" type="ORF">FE772_15480</name>
        <name evidence="7" type="ORF">GLE_3109</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000073">
        <property type="protein sequence ID" value="OPD61733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948048.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000073.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3109"/>
    <dbReference type="EnsemblBacteria" id="ALN58456">
        <property type="protein sequence ID" value="ALN58456"/>
        <property type="gene ID" value="GLE_3109"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61733">
        <property type="protein sequence ID" value="OPD61733"/>
        <property type="gene ID" value="BV903_22060"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3109"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3066"/>
    <dbReference type="OMA" id="FILLAPW"/>
    <dbReference type="OrthoDB" id="2053476at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="6">
        <location>
            <begin position="38"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD61733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW26836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="205" mass="23234" checksum="BAB941A487C67A92" modified="2016-02-17" version="1">MITFVLIAVTVLVSWQAFEKRRLYERLVLWPPGVARFRQYDRLLTHGFVHADWMHLLFNMITLYFFGRAVEGVFAQLAGPGMFALFYLSAIVVAILPSYLRHRKDGGYVSLGASGAVSAVLFAFVLVDPWNWIIVFVIPVPAVVYAIAYVGYSYWMDKRGGDNINHNAHLSGAIYGLLFMLMMKPALFWFFLERLASPRGPGFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJK1</accession>
    <name>A0A0S2DJK1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphate-selective porin O and P</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Porin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_20440</name>
        <name evidence="4" type="ORF">FE772_16380</name>
        <name evidence="2" type="ORF">GLE_3312</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000062">
        <property type="protein sequence ID" value="OPD62053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948198.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000062.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3312"/>
    <dbReference type="EnsemblBacteria" id="ALN58658">
        <property type="protein sequence ID" value="ALN58658"/>
        <property type="gene ID" value="GLE_3312"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62053">
        <property type="protein sequence ID" value="OPD62053"/>
        <property type="gene ID" value="BV903_20440"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3312"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3262"/>
    <dbReference type="OMA" id="QVGQFYE"/>
    <dbReference type="OrthoDB" id="1578713at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010870">
        <property type="entry name" value="Porin_O/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07396">
        <property type="entry name" value="Porin_O_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595712" evidence="1">
        <location>
            <begin position="24"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="430" mass="47371" checksum="C32C6BF67DECF2DE" modified="2016-02-17" version="1">MKLSRTTLAVALLAALAAPAAHAEIALDVIGDSEVTFEGLVQADYNDFNSDVLNLNGDLPDGKDTDQELRRAELVLKGKGPGNFEWVAGYDAKADKFLDVNLKYKIGGDGNHYVQFGQFKQPNSMEELSSTKNNDFISKAMVTNTFGIARRLGVAYSYGTNDWSLTASYFGDELTRNQKHGKGYGLRGTFAPINEKGNVLHLGLSYVNLDAELEGNTGILDNSARIRTRPQVDLASGRLVDSGTLTNVDTQAIIGAEAMYVQGPFKVQAEYMRSTLDRYKTATLTGKDYTTDSWYVSGVWNITGETWGYKSGTPTTPLPNEPATGMWQVGLRYDKIDLNDGSLRPGATPTAAPIVDGVLGGEMSAWTVGVNWYWRSNFKFMLDYSIVDSSRYIGKTSATYSQNPQYNNRTFNRVVDDSPNVLSARLQFYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJK2</accession>
    <name>A0A0S2DJK2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">rpsB</name>
        <name evidence="8" type="ORF">GLE_3362</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948238.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3362"/>
    <dbReference type="EnsemblBacteria" id="ALN58708">
        <property type="protein sequence ID" value="ALN58708"/>
        <property type="gene ID" value="GLE_3362"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3362"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3312"/>
    <dbReference type="OMA" id="SYIDRAY"/>
    <dbReference type="OrthoDB" id="1623045at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00291_B">
        <property type="entry name" value="Ribosomal_S2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_S2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005706">
        <property type="entry name" value="Ribosomal_S2_bac/mit/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018130">
        <property type="entry name" value="Ribosomal_S2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_S2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534">
        <property type="entry name" value="PTHR12534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="SSF52313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01011">
        <property type="entry name" value="rpsB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00962">
        <property type="entry name" value="RIBOSOMAL_S2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00963">
        <property type="entry name" value="RIBOSOMAL_S2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="226"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="280" mass="30352" checksum="6DA79E9CEDD9074A" modified="2016-02-17" version="1">MPQITMRQMLEAGVHFGHQTRYWNPKMGPYIFGARGKIHIINLEKTVPLFNDAMNFISGIAQKRGTILFIGTKRSARESIKEEAERCGMPFMTQRWLGGTLTNFRTVKQSVSRLKELEAGETDGTFQKMVKHEVLGLRRERDKLEASLGGIKDMNRLPDALFVIDIGHEDIAIKEAKKLGIPVIAVVDTNYNPELVDYAIPGNDDAIRAVQLYARAAADAVLEGKAASPTAGGVREEDFAAEAGSEDAGKDGKAPRGRAPAAKKPAAAPAAAKPDAAAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJL7</accession>
    <name>A0A0S2DJL7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.117</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Tetrahydrodipicolinate N-succinyltransferase</fullName>
            <shortName evidence="7">THDP succinyltransferase</shortName>
            <shortName evidence="7">THP succinyltransferase</shortName>
            <shortName evidence="7">Tetrahydropicolinate succinylase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">dapD</name>
        <name evidence="11" type="ORF">FE772_16580</name>
        <name evidence="10" type="ORF">GLE_3358</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(S)-2,3,4,5-tetrahydrodipicolinate + H2O + succinyl-CoA = (S)-2-succinylamino-6-oxoheptanedioate + CoA</text>
            <dbReference type="Rhea" id="RHEA:17325"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15685"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="EC" id="2.3.1.117"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (succinylase route): step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.117" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948236.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3358"/>
    <dbReference type="EnsemblBacteria" id="ALN58704">
        <property type="protein sequence ID" value="ALN58704"/>
        <property type="gene ID" value="GLE_3358"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3358"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3308"/>
    <dbReference type="OMA" id="YFPIQKM"/>
    <dbReference type="OrthoDB" id="752123at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00019"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008666">
        <property type="term" value="F:2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.166.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00811">
        <property type="entry name" value="DapD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005664">
        <property type="entry name" value="DapD_Trfase_Hexpep_rpt_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023180">
        <property type="entry name" value="THP_succinylTrfase_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037133">
        <property type="entry name" value="THP_succinylTrfase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14805">
        <property type="entry name" value="THDPS_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00965">
        <property type="entry name" value="dapD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="THDPS_N_2" evidence="9">
        <location>
            <begin position="32"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF14805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN58704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW27016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="304" mass="32689" checksum="FAFF99F700E8621B" modified="2016-02-17" version="1">MSSAPKKTVKKTTKKAVKAVKKKPQAPGADELKFMIDSAFERRTMLTPDEVEGSTRPTVERVIAGLEQGEFRVAEPDGKGGWKVNEWLKKAVLLYFRVNDMQVVEADPAPFWDKVPARFEGYGEADFRKLGARVVPGAIARRGAYIGKDVVLMPSFVNIGAHVGEGTMVDTWATVGSCAQIGKHCHLSGGAGIGGVLEPLQASPTIIEDHCFIGARSEVVEGFVVGHHSVIGMGVFLGQSTRVYNRATGEISYGYVPPYSVVVSGQLPAKDGSHSLYCAVIVKQVDAKTMAKTSINELLRGLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJN0</accession>
    <name>A0A0S2DJN0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Metal ion efflux RND protein family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_3263</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948161.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3263"/>
    <dbReference type="EnsemblBacteria" id="ALN58609">
        <property type="protein sequence ID" value="ALN58609"/>
        <property type="gene ID" value="GLE_3263"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3263"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3216"/>
    <dbReference type="OMA" id="PRVDANY"/>
    <dbReference type="OrthoDB" id="1099555at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="479"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="233"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="491"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="506" mass="52993" checksum="C44E570A1D3A76D1" modified="2016-02-17" version="1">MSVHDTRPRRGLLYVLAPLAAALILAGCASTRGLQPSGRALDADSLEAKRSLAVADLSAAQFPQRDWWTAFGDAQLNGLIDEALAGSPSLDAADARVRQAVAQAGLADAARKPTLGGSAQYSGAHLPETLAPDPIGGKYLGADVLMLSFKYSPDLWGGKRARWQAALGQSRAAEVEAQAARLTLSSNIARSYVSLAQAFEAQDVAKAEKQRSDKLLGLGQQRVKAGLDNQLQIRNAQSASASADQQIQAAQQQIDAARNALAALLGKGPDRGLSIARPTLLAGNAAGVPDVLPSELLGHRPDVVAARWRVEASSHGIKAAKADFYPTVNLSAIVGLATAHLSDLFTSQARLYQGGPAISMPIFDGGRLRNELAGSDADYDLAVANYNQSLIGALREVADAVQSSRSLDGQLASAQQARDAAQQAWQIATSRYRAGMGTQIDVLTAQRPLLQLDQQLATLRAQRLAARIDLDRALGGGLQLSPPDPVAATVPDASSDNNAIAKAPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJS7</accession>
    <name>A0A0S2DJS7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transglycosylase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_16730</name>
        <name evidence="3" type="ORF">GLE_3392</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948261.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3392"/>
    <dbReference type="EnsemblBacteria" id="ALN58738">
        <property type="protein sequence ID" value="ALN58738"/>
        <property type="gene ID" value="GLE_3392"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3392"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3341"/>
    <dbReference type="OrthoDB" id="2052650at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001264">
        <property type="entry name" value="Glyco_trans_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036950">
        <property type="entry name" value="PBP_transglycosylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00912">
        <property type="entry name" value="Transgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="Transgly" evidence="2">
        <location>
            <begin position="128"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="247" mass="27624" checksum="78E99BBB6C2FDC3E" modified="2016-02-17" version="1">MSRDATATRDRAPRRRRWPIVAGALLIAFAAVPFALPYALYWHALKDLREPLPQAQQRYPDALRQLYWNLHGGHGPIRVRRLSPPGYALELFADPGDGRAASVAADQQLLNRVAGLRQTWLPPHTGMLRWHLTQAALAIRLSREYDGERLIDYVLERDRFADRGAVGIDAAARAYFDLPLRSLSAQEQLALLVLARGPSYFDPACHRDRFARRYARALEKTGLAPTQAIPARMRAETCAQPGGDGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJW2</accession>
    <name>A0A0S2DJW2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_17970</name>
        <name evidence="2" type="ORF">GLE_3425</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000048">
        <property type="protein sequence ID" value="OPD62554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948286.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000048.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58770">
        <property type="protein sequence ID" value="ALN58770"/>
        <property type="gene ID" value="GLE_3425"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62554">
        <property type="protein sequence ID" value="OPD62554"/>
        <property type="gene ID" value="BV903_17970"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3425"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3375"/>
    <dbReference type="OrthoDB" id="2172255at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594859" evidence="1">
        <location>
            <begin position="27"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="73" mass="7657" checksum="28A3A4A9435088CE" modified="2016-02-17" version="1">MKRTMMKVAAAVFAVGLVGGVGVANAQIGGAYCNPNGATTNIVQGSWRNYYTCSNHKWVFVKACPVGGGRCVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK76</accession>
    <name>A0A0S2DK76_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">ATP-dependent Clp protease proteolytic subunit</fullName>
            <ecNumber evidence="5 8">3.4.21.92</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Endopeptidase Clp</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 11" type="primary">clpP</name>
        <name evidence="11" type="ORF">GLE_3419</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 9">Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 10">Belongs to the peptidase S14 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.92" evidence="5 8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3419"/>
    <dbReference type="EnsemblBacteria" id="ALN58765">
        <property type="protein sequence ID" value="ALN58765"/>
        <property type="gene ID" value="GLE_3419"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3419"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3370"/>
    <dbReference type="OMA" id="RDYWMKA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033135">
        <property type="entry name" value="ClpP_His_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018215">
        <property type="entry name" value="ClpP_Ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="PTHR10381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00493">
        <property type="entry name" value="clpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00382">
        <property type="entry name" value="CLP_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00381">
        <property type="entry name" value="CLP_PROTEASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 8" id="KW-0720">Serine protease</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 7">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN58765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="196" mass="21616" checksum="F9ADE3EEE89F4ECE" modified="2016-02-17" version="1">MVVEQTSRGERAYDIYSRLLKERVIFLVGGVDDHVANVIVAQMLFLEAENPEKDINFYINSPGGVVTAGMAIYDTMQYIKPDVSTICIGQAASMGALLLAAGAKGKRLALPNSRVMIHQPLGGFQGQATDIDIHAREILTLRQRLNEILSKHTGQSLETIARDTERDNFKSAEAARDYGLVDQVLERRPDETIQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK89</accession>
    <name>A0A0S2DK89_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter, ATP-binding protein/transmembrane region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLE_3571</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58915">
        <property type="protein sequence ID" value="ALN58915"/>
        <property type="gene ID" value="GLE_3571"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3571"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3515"/>
    <dbReference type="OMA" id="VTIYMAK"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="38"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="356"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="594"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="606"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="388"/>
            <end position="395"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN58915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="620" mass="67564" checksum="87C6BA3483276231" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKC1</accession>
    <name>A0A0S2DKC1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lytic murein transglycosylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3603</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transglycosylase Slt family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3603"/>
    <dbReference type="EnsemblBacteria" id="ALN58947">
        <property type="protein sequence ID" value="ALN58947"/>
        <property type="gene ID" value="GLE_3603"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3603"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3546"/>
    <dbReference type="OMA" id="EASAWAW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008933">
        <property type="term" value="F:lytic transglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000270">
        <property type="term" value="P:peptidoglycan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000189">
        <property type="entry name" value="Transglyc_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008258">
        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00922">
        <property type="entry name" value="TRANSGLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SLT" evidence="2">
        <location>
            <begin position="203"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="329" mass="33844" checksum="A3F093E8F1B33836" modified="2016-02-17" version="1">MLGLLAFAPAAAGTLWRCDSPSGERSYVSKKVKGATCTVVSQYTSKASRPRDPAPVAYAPPKPAPAMGSVGAGGDAAIPASAHSNPPATYAGAAAAMVAGGISGAAAASAPAPAIAPAPAPAAAPVPAAPGQAPTRLVQGQIYSYVQDGVRHYVSKRPKGLANATQMRTIRYSFIETCFACAARPGVNFGTLRLNTAAYSAEIAAAARQHGVEEAIVRAIIHAESAYNPNALSRAGAQGLMQLMPATARRFGVGNAFDASQNIQGGVQYLAWLLKRFNGDLTLASAGYNAGEGAVDKYKGVPPYSETQRYVQRVAVLAQRYRSAGVVQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKC8</accession>
    <name>A0A0S2DKC8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3648</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58992">
        <property type="protein sequence ID" value="ALN58992"/>
        <property type="gene ID" value="GLE_3648"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3648"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3592"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="43" mass="4607" checksum="33CF1D58906E09CD" modified="2016-02-17" version="1">MIAITDAAETFVYKAASPTGRPARRRAKPRRTPHAAQEIGDGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL32</accession>
    <name>A0A0S2DL32_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3891</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59234">
        <property type="protein sequence ID" value="ALN59234"/>
        <property type="gene ID" value="GLE_3891"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3891"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="60" mass="6423" checksum="F877B3DF6560F593" modified="2016-02-17" version="1">MDSSKRIGIAAGRLERRGRVSSRFGVEKRGGSRMAPVSAVWRGRGLRRSYTGGGCGGRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL49</accession>
    <name>A0A0S2DL49_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha,alpha-trehalose-phosphate synthase</fullName>
            <ecNumber evidence="3">2.4.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">otsA</name>
        <name evidence="3" type="ORF">GLE_3709</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.15" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3709"/>
    <dbReference type="EnsemblBacteria" id="ALN59053">
        <property type="protein sequence ID" value="ALN59053"/>
        <property type="gene ID" value="GLE_3709"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3709"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3654"/>
    <dbReference type="OMA" id="YYGFSNR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003825">
        <property type="term" value="F:alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03788">
        <property type="entry name" value="GT20_TPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="PTHR10788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00982">
        <property type="entry name" value="Glyco_transf_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="456"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="508" mass="55030" checksum="8F51E1504F8E0579" modified="2016-02-17" version="1">MSRTVIVSNRVALPGAQRPGGLAIALQAALRESEGLWFGWSGRSGAATEIPQRCRERGIDYATLDLSQDDVDAYYRGFANRVLWPLLHSRVDLVDYRRECSDGYQRVNAGFARALARELRGDDAIWVHDYHLIPLAAQLRRLGVDNRIGFFLHVPFPPADLAATLPHHRELFDPLRAYDLIGLQTRTDAAHLAEYLQTHAGLRALGGGRWRGDEGRTTRIGAFPIGIDTDAIAAQAADAAALAEVRRLRDSLGGRRLVIGVDRLDYSKGLPERMRAFERHLQRHPDLCGQLTYLQIAPLSRSDVPEYRSLRAELEALAGHVNGAHARPDWTPIRYVNHDYPHSALTGFYRSAAVGLVTPLRDGMNLVAKEYVASQAAADPGALVLSRFAGAADQLGEALLVNPHDADEVADAVAAAARMPLAQRRERWAAMMASLRASDIGAWRRGFLQALAETAPAPAQDGVRGEARAASSPSPSPSPSPSMAARGLAALAPAPLLAPGSLLSKGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL76</accession>
    <name>A0A0S2DL76_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TPM_phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_3924</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3924"/>
    <dbReference type="EnsemblBacteria" id="ALN59266">
        <property type="protein sequence ID" value="ALN59266"/>
        <property type="gene ID" value="GLE_3924"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3924"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3861"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007621">
        <property type="entry name" value="TPM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04536">
        <property type="entry name" value="TPM_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="1 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595203" description="TPM_phosphatase domain-containing protein" evidence="6">
        <location>
            <begin position="39"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="263"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="317"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="348"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="381"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="TPM_phosphatase" evidence="7">
        <location>
            <begin position="66"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="410"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="410"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="434"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="472" mass="48691" checksum="18719AB5E18B7FA0" modified="2016-02-17" version="1">MVMAADGASLRARPLRCGAMIVVLLCLFAWASALSAQARAPAPAPANAAPVLDSPTLDSRTLNSPVQDLAGALRPDTRERLETRARELRARKGAQLQVLIVASTAPESIDAYAQRVFDAWALGRRGVDDGVLLVVARDDRRARIQVGYGLEGRIPDAAARDVLSAYLLPHLARGEYDAGVDAASAALAALVEQEPLPAPAADAYAAAASAWSPLARICALGAAFALVLGWCAQRRGWPLAWAAPAALLPPAVAAWVWSGPAWLWLPLLCGAVAGALGLALPRWRWLRSVAGAAAVGLAVAALGAALVRRGVPAPGDIGLGAVAVLFATPLLVGAIAPPMIAWQERGRLGFALRAGALAAIAWLAWRVLLRMTDGDPSGLGGGGWLGVGLFAYLAWVLVFLLNGEIWGGRSRKRDGRGGRRRNGDSERKQRSGDAGSSHSGPSRSESSDSGAGDTGWSGGGGRSGGGGASGSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLQ4</accession>
    <name>A0A0S2DLQ4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Threonine-phosphate decarboxylase</fullName>
            <ecNumber evidence="5">4.1.1.81</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">L-threonine-O-3-phosphate decarboxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLE_4086</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + O-phospho-L-threonine = (R)-1-aminopropan-2-yl phosphate + CO2</text>
            <dbReference type="Rhea" id="RHEA:11492"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58563"/>
            <dbReference type="ChEBI" id="CHEBI:58675"/>
            <dbReference type="EC" id="4.1.1.81"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.81" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948771.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4086"/>
    <dbReference type="EnsemblBacteria" id="ALN59428">
        <property type="protein sequence ID" value="ALN59428"/>
        <property type="gene ID" value="GLE_4086"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4086"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4028"/>
    <dbReference type="OMA" id="RDPWSVN"/>
    <dbReference type="OrthoDB" id="1248286at2"/>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:threonine-phosphate decarboxylase activity"/>
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        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901605">
        <property type="term" value="P:alpha-amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
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        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005860">
        <property type="entry name" value="CobD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01140">
        <property type="entry name" value="L_thr_O3P_dcar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="8 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="10">
        <location>
            <begin position="60"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN59428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="330" mass="36068" checksum="3BF5CA4D8A414920" modified="2016-02-17" version="1">MLEHGGRLLRAAQRYGIPAADWLDLSTGINPQAWPVPEIPARAWQRLPEDDDGLAEIAAAYYGAPQALPVAGSQAAIQALPELRSPARVGVIAPGYAEHAHAWRRAGHAVETLPAHELLAQRARFDVVVLIHPNNPGGERFEREALLVLHQDLAARGGWLLIDEAFMDATPERSLCGESARGGLIVLRSAGKFFGLAGARAGFVCAAPALLAALRERLGPWTLTGPARHVLRHALADRDWQRHMRAQLQTQAERLAAMLRAHGLAPSGGSAFFQWRRDPRAARLHEALARRAILTRLFEQPASLRFGLPGGEDEWRRLETALAELGDCLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-10-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLQ8</accession>
    <name>A0A0S2DLQ8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">TonB family C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLE_4160</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TonB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59502">
        <property type="protein sequence ID" value="ALN59502"/>
        <property type="gene ID" value="GLE_4160"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4160"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4102"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="TonB_C" evidence="10">
        <location>
            <begin position="87"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN59502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="169" mass="18508" checksum="31EDB12EC5B799ED" modified="2016-02-17" version="1">MVAPPSPPSNSPDFSQDIGMTETYYIPACRMGMPGGAYRASWREISDFHDKNGVAWLSELDRHGAPDWYARPGSRAPEPDNRPDAAYPAAAGGKVGEVVVKVVIDAKGRTRDAMVICSNDTVFDAPALAFARKVVFKPALRDGRAVADYGNVSMRFYPDGPQYGFRRHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLV4</accession>
    <name>A0A0S2DLV4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AAA family ATPase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Transcriptional regulatory protein RtcR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_21265</name>
        <name evidence="2" type="ORF">GLE_4350</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948983.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4350"/>
    <dbReference type="EnsemblBacteria" id="ALN59691">
        <property type="protein sequence ID" value="ALN59691"/>
        <property type="gene ID" value="GLE_4350"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4350"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4289"/>
    <dbReference type="OMA" id="CWFLLTE"/>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009715">
        <property type="entry name" value="RtcR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017183">
        <property type="entry name" value="Sigma54_dep_tscrpt_act_RtcR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32071:SF14">
        <property type="entry name" value="PTHR32071:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06956">
        <property type="entry name" value="RtcR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037354">
        <property type="entry name" value="Txn_actvtr_RtcR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="1">
        <location>
            <begin position="185"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="529" mass="59636" checksum="C598C4FE040DC0BF" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLV7</accession>
    <name>A0A0S2DLV7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aspartyl beta-hydroxylase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Aspartyl/asparaginyl beta-hydroxylase family</fullName>
            <ecNumber evidence="3">1.14.11.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_07745</name>
        <name evidence="3" type="ORF">GLE_4162</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">B25</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.14.11.16" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000015">
        <property type="protein sequence ID" value="OPD64545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4162"/>
    <dbReference type="EnsemblBacteria" id="ALN59504">
        <property type="protein sequence ID" value="ALN59504"/>
        <property type="gene ID" value="GLE_4162"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64545">
        <property type="protein sequence ID" value="OPD64545"/>
        <property type="gene ID" value="BV903_07745"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4162"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4104"/>
    <dbReference type="OMA" id="YAGSYRY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062101">
        <property type="term" value="F:peptidyl-aspartic acid 3-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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            <end position="299"/>
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            <begin position="70"/>
            <end position="223"/>
        </location>
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    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD64545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="300" mass="34987" checksum="82AADA5D698D5F76" modified="2016-02-17" version="1">MKWVFVFLFLAAAVYVHFRGRVRHRLGRQLLDHSTFMAPINVLMYACSKVPTTPYLKPDEHFPELEPLRARWREVRAEALHLREMQQIKAADQYNDVGFNSFFRRGWKRFYLKWYDEAHPSAAELCPVTTQLLREVPSVKAAMFTELPPGSELRPHRDPYAGSLRLHLGLETPNDDACFIDVDGQRYSWRDGEWTMFDETYIHWAQNGSQHNRIILFCDIERPMRFAWARGLNRFIAKRLIAAGASPNSEGDKTGAINKIFKYFYALRLKSKALKERSKGAYYFFKYAAVAAVIALIVWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLV8</accession>
    <name>A0A0S2DLV8_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">FG-GAP repeat</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
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        <name type="scientific">Lysobacter enzymogenes</name>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
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    </evidence>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
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            <dbReference type="EMBL" id="ALN59566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="791" mass="83580" checksum="AAA44CD73DF43156" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMH1</accession>
    <name>A0A0S2DMH1_LYSEN</name>
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        </submittedName>
    </protein>
    <gene>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
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                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">OH11</strain>
        </source>
    </reference>
    <reference evidence="7 11" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 11">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
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            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
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    </comment>
    <comment type="similarity">
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    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_4292"/>
    <dbReference type="EnsemblBacteria" id="ALN59633">
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        <property type="gene ID" value="GLE_4292"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4292"/>
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    <dbReference type="OMA" id="ATTAMKY"/>
    <dbReference type="OrthoDB" id="1921902at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:response to chemical"/>
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        <property type="project" value="UniProt"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Small_multidrug_res"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </feature>
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        </location>
    </feature>
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    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW27754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROU08009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="111" mass="11342" checksum="A8CF25AAAD42761E" modified="2016-02-17" version="1">MNPGYLYLAVAIAAEVIATSALKASEGFTKTGPSLVVAAGYGVAFYFLSLVLKTVPVGVAYAIWSGVGIVLIALIGWLFMKQQLDAGAVAGIGLIVAGVLVIQLFSKSAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMW1</accession>
    <name>A0A0S2DMW1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Drug/metabolite exporter YedA</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Integral membrane protein DUF6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">yedA</name>
        <name evidence="4" type="ORF">BV903_03305</name>
        <name evidence="5" type="ORF">FE772_21805</name>
        <name evidence="3" type="ORF">GLE_4468</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000006">
        <property type="protein sequence ID" value="OPD65334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4468"/>
    <dbReference type="EnsemblBacteria" id="ALN59809">
        <property type="protein sequence ID" value="ALN59809"/>
        <property type="gene ID" value="GLE_4468"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65334">
        <property type="protein sequence ID" value="OPD65334"/>
        <property type="gene ID" value="BV903_03305"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4468"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4405"/>
    <dbReference type="OMA" id="AYGLFFY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="277"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="23"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="159"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD65334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW27889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="325" mass="33907" checksum="3DC5D72E1F16C0D5" modified="2016-02-17" version="1">MSAPAAPPSDPRAPGPLAVAFALASVYVLWGSTYLGIRFALESYPPFLLGAARMFLAGAIMWVVLRRRGVPAPTRKQWRTLWVLSIFMVLLSNGLVNLAETQVDSGLAAIAVASMPLFAGVFAMLRGRHPSKIEWAGLAVGFAGVVWLNAGGKLSASTLGLVCLIVAPIAWAWGSIWSRDLDLPSPFMTASAQMLTGSAWMLGAAAVTGERIVQVPTFGATAALLYLVVAGSIFGFTAYIWLLHHVRPALATSYAYVNPPIAVLFGALLAGERFTSHDLGAMAVILVGVVIITLAKARAAKAAPVAAAVASAPAVVAASELEKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMW8</accession>
    <name>A0A0S2DMW8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphoribosylaminoimidazole-succinocarboxamide synthase</fullName>
            <ecNumber evidence="8">6.3.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">SAICAR synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">purC</name>
        <name evidence="11" type="ORF">BV903_04620</name>
        <name evidence="12" type="ORF">FE772_21005</name>
        <name evidence="10" type="ORF">GLE_4290</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">C3</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + ATP + L-aspartate = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:22628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the SAICAR synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.6" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000008">
        <property type="protein sequence ID" value="OPD65207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948938.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000008.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4290"/>
    <dbReference type="EnsemblBacteria" id="ALN59631">
        <property type="protein sequence ID" value="ALN59631"/>
        <property type="gene ID" value="GLE_4290"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65207">
        <property type="protein sequence ID" value="OPD65207"/>
        <property type="gene ID" value="BV903_04620"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4290"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4229"/>
    <dbReference type="OMA" id="TKFEFGF"/>
    <dbReference type="OrthoDB" id="1345271at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00131"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004639">
        <property type="term" value="F:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00137">
        <property type="entry name" value="SAICAR_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028923">
        <property type="entry name" value="SAICAR_synt/ADE2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001636">
        <property type="entry name" value="SAICAR_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018236">
        <property type="entry name" value="SAICAR_synthetase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01259">
        <property type="entry name" value="SAICAR_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00081">
        <property type="entry name" value="purC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01058">
        <property type="entry name" value="SAICAR_SYNTHETASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAICAR_synt" evidence="9">
        <location>
            <begin position="17"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OPD65207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW27753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="309" mass="33762" checksum="61A0DD0F0573BD19" modified="2016-02-17" version="1">MTTTLLQSELPGLPLRHRGKVRDVFDLPADRLPAGATPGGDCLLMVATDRLSAFDVVLPDPIPGKGEMLCQISNFWFGKTAHIIPNHLTGIDVAAVLPEGVDAGLYAKRAVVTKRLKPVAIECIARGYVIGSGWKDYQRTGRISGIALPGGLRQAEKLPEPIFTPSTKAAVGDHDENIDFDTAVRTVGAELAEAVRDATLRLYRYAADYAAQRGILLADTKFEFGTDADGRLYVMDEMLTPDSSRYWPADEYQVGTSPPSYDKQFVRDYLETLDWDKTPPGPSLPAQVIERTRAKYAEALQKLAGISVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN02</accession>
    <name>A0A0S2DN02_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_03240</name>
        <name evidence="5" type="ORF">D9T17_07020</name>
        <name evidence="4" type="ORF">FE772_21740</name>
        <name evidence="2" type="ORF">GLE_4454</name>
    </gene>
    <organism evidence="2 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">C3</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 9" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000006">
        <property type="protein sequence ID" value="OPD65322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000019">
        <property type="protein sequence ID" value="ROU07943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949067.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4454"/>
    <dbReference type="EnsemblBacteria" id="ALN59795">
        <property type="protein sequence ID" value="ALN59795"/>
        <property type="gene ID" value="GLE_4454"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65322">
        <property type="protein sequence ID" value="OPD65322"/>
        <property type="gene ID" value="BV903_03240"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4454"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4391"/>
    <dbReference type="OMA" id="LRQTWRA"/>
    <dbReference type="OrthoDB" id="1830300at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD65322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU07943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="124" mass="13339" checksum="9CF758306CDF34A2" modified="2016-02-17" version="1">MSRFDRLQRRVDKRERLLEGRYEQVQERKQVLQRSWREAWTPGRIVIAGLVSGFFMGRAEPVKIAVKSGNLMQIVSLLSGLFAGAGAQEAADQAGQAAGQAGRAARAADQAADGAQAAAERSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN19</accession>
    <name>A0A0S2DN19_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar basal body protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">flgG</name>
        <name evidence="8" type="ORF">BV903_14235</name>
        <name evidence="9" type="ORF">FE772_22580</name>
        <name evidence="7" type="ORF">GLE_4629</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="69.GLE_4629"/>
    <dbReference type="EnsemblBacteria" id="ALN59970">
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        <property type="gene ID" value="GLE_4629"/>
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        <property type="gene ID" value="BV903_14235"/>
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        <property type="component" value="Chromosome"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="entry name" value="Flag_bb_rod_N"/>
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    </dbReference>
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        <property type="entry name" value="Flagellar_FlgE/F/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037925">
        <property type="entry name" value="FlgE/F/G-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF117143"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FlgEFG_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FLAGELLA_BB_ROD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="5">
        <location>
            <begin position="5"/>
            <end position="35"/>
        </location>
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    <feature type="domain" description="Flg_bbr_C" evidence="6">
        <location>
            <begin position="177"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD63286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW28014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="256" mass="26446" checksum="75EACF353428261C" modified="2016-02-17" version="1">MNGIFYIGATGLDAQGKAVETVANNVANINTAAYKRGTVSFSELLSADAANGAAGADEVKRAAAGVMANPTLHVFAQGDLRPTGNDMDIAVQGEGFLELAGGDGRTTLWRGGTLRIGADGFLAAANGLPLASMIAVPADAEAIHIAKNGMVTATLRNERTPVEIGQIELAVPADLQRMESLGDGLYALPDDALSVTRSVPGEDKAGLVAQGFSEASNIKLADEMVSLMIYQRAYASSARLVQIGDELMGIANGLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNC1</accession>
    <name>A0A0S2DNC1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_03650</name>
        <name evidence="4" type="ORF">FE772_22185</name>
        <name evidence="2" type="ORF">GLE_4544</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000006">
        <property type="protein sequence ID" value="OPD65391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949136.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000006.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59885">
        <property type="protein sequence ID" value="ALN59885"/>
        <property type="gene ID" value="GLE_4544"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65391">
        <property type="protein sequence ID" value="OPD65391"/>
        <property type="gene ID" value="BV903_03650"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4544"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4480"/>
    <dbReference type="OrthoDB" id="2100936at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD65391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="67" mass="7199" checksum="DF0FA8EB9CBF4572" modified="2016-02-17" version="1">MDFVFGFAAYGGPIWTAALLAWVGYRERVRRPGFNRWHLAAIVSAALGVGALFVLQKMGAAMRATGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNT2</accession>
    <name>A0A0S2DNT2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4804</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60145">
        <property type="protein sequence ID" value="ALN60145"/>
        <property type="gene ID" value="GLE_4804"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4804"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4736"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="72" mass="8583" checksum="1A7F868EED2D48BA" modified="2016-02-17" version="1">MDWTSRLPSPFPFPFPFPSSRRKPQPSRRRKPQPSFRRTPESILILLSRSPHAVRPRLFQKQQQNGFRLSPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNU6</accession>
    <name>A0A0S2DNU6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ADP-ribosylation/Crystallin J1</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">ADP-ribosylglycohydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_23415</name>
        <name evidence="1" type="ORF">GLE_4820</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949336.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4820"/>
    <dbReference type="EnsemblBacteria" id="ALN60161">
        <property type="protein sequence ID" value="ALN60161"/>
        <property type="gene ID" value="GLE_4820"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4820"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4751"/>
    <dbReference type="OMA" id="PGTWTDD"/>
    <dbReference type="OrthoDB" id="1661477at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005502">
        <property type="entry name" value="Ribosyl_crysJ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036705">
        <property type="entry name" value="Ribosyl_crysJ1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03747">
        <property type="entry name" value="ADP_ribosyl_GH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101478">
        <property type="entry name" value="SSF101478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="313" mass="33499" checksum="D713054CCC944FE8" modified="2016-02-17" version="1">MNAVAARPDLSERYLGCLLGLACGDAVGTTVEFKARGDFAPLTDMTGGGPFGLRAGEWTDDTSMALCLGASLLHCRGFDPRDQMNRYCNWRAHGYLSSNGECFDIGATVSAALDRYLRSGDPYAGDPGPRAAGNGALMRLAPVPMLWRRDPERLRRYAAESTRTTHGAAEALDCSRLFASQVRAALMGAGKEAVLTPAMPPPQSEKVAAIHARGYAGKREDEIRGSGYSVESLEAALWCFLHTDSFEAAILRAANLGEDADTTAAICGQVAGAFYGVQGIPEAWLRRLVMREDIAAMAQALLVLSDEPFETAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNW0</accession>
    <name>A0A0S2DNW0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome d ubiquinol oxidase subunit II</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Cytochrome d ubiquinol oxidase, subunit II</fullName>
            <ecNumber evidence="8">1.10.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cydB</name>
        <name evidence="9" type="ORF">BV903_06810</name>
        <name evidence="10" type="ORF">FE772_23930</name>
        <name evidence="8" type="ORF">GLE_4933</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome ubiquinol oxidase subunit 2 family.</text>
    </comment>
    <dbReference type="EC" id="1.10.3.-" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="OPD64737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="STRING" id="69.GLE_4933"/>
    <dbReference type="EnsemblBacteria" id="ALN60274">
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        <property type="gene ID" value="GLE_4933"/>
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        <property type="protein sequence ID" value="OPD64737"/>
        <property type="gene ID" value="BV903_06810"/>
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    <dbReference type="OMA" id="TAWAYWV"/>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:oxidoreductase activity"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="cydB"/>
        <property type="match status" value="1"/>
    </dbReference>
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            <begin position="7"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <begin position="75"/>
            <end position="100"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <begin position="299"/>
            <end position="318"/>
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    </feature>
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            <dbReference type="ARBA" id="ARBA00004141"/>
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    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW28240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="334" mass="36863" checksum="27181DDBA5564C06" modified="2016-02-17" version="1">MDYWLPVIWFGVIGFGVLMYVLLDGFVLGLGILAPFAEDEDQLDHMMNTAAPIWDGNETWLVLGGVGLLTAFPKAYSLVLSALYLPVLLMLIALVFRGVAFEFRFKARRAKAAWGAAFSLGSLFCAFAQGVILGAIVEGMPMQEGKYVGGMFDWFSPFSMLTGAAVVFGYALLGSTWLVLKTEGRLQYIARTLARPLALVVAVFIGLVSAWLPFLDSRIMARWFEGGNFYWLFPVPLLVIANAWALWRSVRREGRDGDPFVYSLGFFVLGFVGLVLGIWPNIVPGLTLWEAAAARSSQMFVLGGMVILLPAILGYTYWSYRVFRGKVAADAGYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNX5</accession>
    <name>A0A0S2DNX5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4893</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60234">
        <property type="protein sequence ID" value="ALN60234"/>
        <property type="gene ID" value="GLE_4893"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4893"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4824"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="202" mass="21465" checksum="DF02333FFBDA7E9F" modified="2016-02-17" version="1">MEFVHGASSEPAPGRARPPAGGRDVRRRAVPGARGPAADSFLRVAPSPCVSECKKSTARPRRSAPGQGLYPCTSGASGGRWALVLIGVAKGGRNKRCGIPPRRADANASKGDVARMRCAAPSGSISPSAQVMSIKVDERHITSRIFTGATVRDLSQDGYVKVFLQRRVLSSSSVEFAKNAKFQGKTTMSRDVDDSRSITREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP22</accession>
    <name>A0A0S2DP22_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BV903_13590</name>
        <name evidence="11" type="ORF">FE772_22955</name>
        <name evidence="9" type="ORF">GLE_4722</name>
    </gene>
    <organism evidence="9 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="9 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">C3</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000035">
        <property type="protein sequence ID" value="OPD63322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949260.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4722"/>
    <dbReference type="EnsemblBacteria" id="ALN60063">
        <property type="protein sequence ID" value="ALN60063"/>
        <property type="gene ID" value="GLE_4722"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63322">
        <property type="protein sequence ID" value="OPD63322"/>
        <property type="gene ID" value="BV903_13590"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4722"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4656"/>
    <dbReference type="OMA" id="AWIFKTG"/>
    <dbReference type="OrthoDB" id="1891092at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00164">
        <property type="entry name" value="ABC2TRNSPORT"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="8">
        <location>
            <begin position="6"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN60063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD63322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW28076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="253" mass="28200" checksum="3FE3423CBBEFD4F7" modified="2016-02-17" version="1">MNLHAIKAIYFFEMHRTFRTLMQSIATPVLSTSLYFIVFGSAIGSRMVEIGGVSYAAFIVPGLIMMSLLTESISNASFGIYLPKWSGTIYELLSAPVSFIEAICGYVGAAATKSVILGTLMLITARFFVDFEIVHPLWMIAFLVLTAVTFSLFGFIIGVWADGFEKLQMIPMMIVMPLTFLGGSFYSIDMLPPFWRSVSLFNPVVYLVNGFRWSFYGKSDVDIGLSVGMTAGFMVLCLVVVWWIFRTGYKLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP35</accession>
    <name>A0A0S2DP35_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4957</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60298">
        <property type="protein sequence ID" value="ALN60298"/>
        <property type="gene ID" value="GLE_4957"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4957"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4884"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="40" mass="3522" checksum="116C06C9839B05BC" modified="2016-02-17" version="1">MGAGGGAAGLGAGGGNGRSGIAWVSSPTPXXXXXXXSGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP80</accession>
    <name>A0A0S2DP80_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60111">
        <property type="protein sequence ID" value="ALN60111"/>
        <property type="gene ID" value="GLE_4770"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4770"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="105" mass="11267" checksum="EA66050AE6093253" modified="2016-02-17" version="1">MQGAGKRLVHRSRGPCGRASCLWGRIRVSSLTNGGDGSACFRWSEGWDSPFWLGGLGGYAGVWWVAPAVVLARSRLAPLLQIAHVGAARAATALPRWPALHTYRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPK2</accession>
    <name>A0A0S2DPK2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA recombination protein RmuC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_5241</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in DNA recombination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RmuC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949657.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5241"/>
    <dbReference type="EnsemblBacteria" id="ALN60582">
        <property type="protein sequence ID" value="ALN60582"/>
        <property type="gene ID" value="GLE_5241"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5241"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5160"/>
    <dbReference type="OMA" id="GDSKMQG"/>
    <dbReference type="OrthoDB" id="1309809at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003798">
        <property type="entry name" value="DNA_recombination_RmuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30563">
        <property type="entry name" value="PTHR30563"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02646">
        <property type="entry name" value="RmuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="492"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="37"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="527" mass="58480" checksum="7F90E4A19E83447F" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPL3</accession>
    <name>A0A0S2DPL3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sulfate ABC transporter substrate-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Sulfate ABC transporter, sulfate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_24180</name>
        <name evidence="7" type="ORF">GLE_4988</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prokaryotic sulfate-binding protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4988"/>
    <dbReference type="EnsemblBacteria" id="ALN60329">
        <property type="protein sequence ID" value="ALN60329"/>
        <property type="gene ID" value="GLE_4988"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4988"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4915"/>
    <dbReference type="OMA" id="KDFGGWK"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901681">
        <property type="term" value="F:sulfur compound binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902358">
        <property type="term" value="P:sulfate transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01005">
        <property type="entry name" value="PBP2_CysP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034408">
        <property type="entry name" value="Sulphate/thiosulphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005669">
        <property type="entry name" value="Thiosulph/SO4-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30368">
        <property type="entry name" value="PTHR30368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00971">
        <property type="entry name" value="3a0106s03"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00757">
        <property type="entry name" value="PROK_SULFATE_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0574">Periplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242470" evidence="6">
        <location>
            <begin position="22"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN60329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW28281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="333" mass="36441" checksum="E743697749C0F334" modified="2016-02-17" version="1">MKTAFRWVLLSVALAAGTAAAKDAELLNVSYDPTREFYAEVNQVFAAQWKQQTGETLNIRTSHGGSGKQARAVVDGLEADVVTLALAGDIDTVANAKQLPADWQKRLPHQSSPYTSTIVFLVRKGNPKGIKDWDDLIKPGVGVITPNPKTSGGARWNYLAAWAWASTKFREGDKVTGYLTQLFKNVPVLDTGARGSTTTFVDRKIGDVLIAWENEALLTLDQSNSRGQFEIVVPSLSIKAEPPVAWVDKNVDKHGTRKQAEAYLRFLYTPEGQRLAAKHGYRPAEPDKVPAAELAKFPAVKQVTIDGAFGGWKKAQAAHFSDGGFFDKIYQPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPP3</accession>
    <name>A0A0S2DPP3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5242</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60583">
        <property type="protein sequence ID" value="ALN60583"/>
        <property type="gene ID" value="GLE_5242"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5242"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5161"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="84" mass="9582" checksum="DFB710BEA056C116" modified="2016-02-17" version="1">MHGIRWRDIDGIDGYAIDAADRRLVYLALGTASGERLELRTDWPGYQDVTRALSAHLPGLDVDALRRLDQARPEDPPAILWWRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ19</accession>
    <name>A0A0S2DQ19_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB-dependent siderophore receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLE_5026</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949497.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5026"/>
    <dbReference type="EnsemblBacteria" id="ALN60367">
        <property type="protein sequence ID" value="ALN60367"/>
        <property type="gene ID" value="GLE_5026"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5026"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4954"/>
    <dbReference type="OMA" id="RQTFTFK"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015344">
        <property type="term" value="F:siderophore uptake transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010105">
        <property type="entry name" value="TonB_sidphr_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01783">
        <property type="entry name" value="TonB-siderophor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595114" evidence="7">
        <location>
            <begin position="27"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="85"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="306"/>
            <end position="750"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN60367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="751" mass="80986" checksum="853D4B2506C54F60" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ21</accession>
    <name>A0A0S2DQ21_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Metal ion efflux RND protein family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_5224</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949646.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5224"/>
    <dbReference type="EnsemblBacteria" id="ALN60565">
        <property type="protein sequence ID" value="ALN60565"/>
        <property type="gene ID" value="GLE_5224"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5224"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5142"/>
    <dbReference type="OMA" id="ITWAAFD"/>
    <dbReference type="OrthoDB" id="1619477at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006519688" evidence="2">
        <location>
            <begin position="21"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="105"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="183"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="483" mass="52402" checksum="D95A0E1003D5D71B" modified="2016-02-17" version="1">MRNLKLPAVALLTLALAACAVGPDYVRPTLAMPDKFARGDAEAATDGTAAPDPAAEFWRNFNDPTLTRLVEESLGANHDLRIALANYDRANALLRGAKFDRFPTITGSATGSDTRSSSDQMPGTDNRGRDNESYSAQANVSWELDVFGRVRRNVESQRADTWASAADLQAMQVAIVGEVARSYVELRGLQERLRVARENAENQQETLRLVQARFDAGRGTEFDTARARAQLEATLARVPNLEAQVAVTQHRLAVLTGQTPDSLVAELDQAAPLPALPARLDAGTPGELLRRRPDVAAAEHRLHAATARIGVATADLFPRFTLSGLIGSQAIDTSALFERASETRLVALGIDWSFLDIGRVRSRIKAADASAEGELARYQQSVLLALEDTENALVRYARARVEDQHLERAAQDSLKAAKLARVRYEAGAADLFEVLDAERTQLQAQDAFADGRTRSVTGAIALYKAMAGGWPAREPVREGVARN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ91</accession>
    <name>A0A0S2DQ91_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Indolepyruvate ferredoxin oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="12">Indolepyruvate ferredoxin oxidoreductase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FE772_25180</name>
        <name evidence="11" type="ORF">GLE_5200</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949628.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5200"/>
    <dbReference type="EnsemblBacteria" id="ALN60541">
        <property type="protein sequence ID" value="ALN60541"/>
        <property type="gene ID" value="GLE_5200"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5200"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5119"/>
    <dbReference type="OMA" id="PRVVGKF"/>
    <dbReference type="OrthoDB" id="37279at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016903">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07034">
        <property type="entry name" value="TPP_PYR_PFOR_IOR-alpha_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019752">
        <property type="entry name" value="Pyrv/ketoisovalerate_OxRed_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01558">
        <property type="entry name" value="POR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="SSF53323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="TPP_enzyme_C" evidence="10">
        <location>
            <begin position="472"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="domain" description="POR" evidence="9">
        <location>
            <begin position="744"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="957"/>
            <end position="983"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN60541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW28455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="1232" mass="135208" checksum="D65C864BFC44B07F" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ93</accession>
    <name>A0A0S2DQ93_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Energy transducer TonB</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="12">TonB family C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BV903_04905</name>
        <name evidence="15" type="ORF">D9T17_03185</name>
        <name evidence="14" type="ORF">FE772_25760</name>
        <name evidence="12" type="ORF">GLE_5331</name>
    </gene>
    <organism evidence="12 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 16">C3</strain>
        </source>
    </reference>
    <reference evidence="13 17" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 17">B25</strain>
        </source>
    </reference>
    <reference evidence="15 18" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 18">OH11</strain>
        </source>
    </reference>
    <reference evidence="14 19" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 19">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TonB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000009">
        <property type="protein sequence ID" value="OPD65080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000010">
        <property type="protein sequence ID" value="ROU08669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949726.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5331"/>
    <dbReference type="EnsemblBacteria" id="ALN60672">
        <property type="protein sequence ID" value="ALN60672"/>
        <property type="gene ID" value="GLE_5331"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65080">
        <property type="protein sequence ID" value="OPD65080"/>
        <property type="gene ID" value="BV903_04905"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5331"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5248"/>
    <dbReference type="OMA" id="ARTQPYN"/>
    <dbReference type="OrthoDB" id="2074833at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_C" evidence="11">
        <location>
            <begin position="146"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="49"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="88"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN60672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OPD65080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW28547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROU08669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="225" mass="24180" checksum="908354155BEEC3F2" modified="2016-02-17" version="1">MTQDLELQVRKDDDREGLNWARIAGITCAIAVHAAALLLLLAPMTPPAQQQDKEEVTMVNIIKPPPPPPPPPPPPPEPPKEIKQPPKELSPPRPTPTPPPPEQPPIENLDPSPVDPPAPPPAPPAPPTAASDIGSSVDPSSRRLNPPKYPPTEARQGVGGTVVLVISIDGQGNVLDVQVEKSSRNRNLDRAAMDAARKWRFNPEMKNGQPVASRVRVPVDFVPPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQD9</accession>
    <name>A0A0S2DQD9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA polymerase sigma factor, ECF family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Sigma-70 family RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_00455</name>
        <name evidence="2" type="ORF">GLE_5445</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949814.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60786">
        <property type="protein sequence ID" value="ALN60786"/>
        <property type="gene ID" value="GLE_5445"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5445"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5361"/>
    <dbReference type="OMA" id="WIRREMS"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011517">
        <property type="entry name" value="RNA_pol_sigma70_ECF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07638">
        <property type="entry name" value="Sigma70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02999">
        <property type="entry name" value="Sig-70_X6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="198" mass="22359" checksum="AC35DA047E11D941" modified="2016-02-17" version="1">MTAADPPPDLGPSDITHLLQDWREGDRQAEAQLLERIYPVLRRLARQRLARSGQVTLRATELANDAYFELARQREVEFQNRAHFYAIAAHAIRRLLVDHLRERSALKRGGDLLRVTLQAGEELVAPAADLVDALDLDRLLERLQRINARAARGVELRYFGGLTIEETAQTIGVSLPTAKRDWQFARAWLHDQLSAAPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQY7</accession>
    <name>A0A0S2DQY7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0002</name>
        <name evidence="3" type="ORF">GLE_5540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55361">
        <property type="protein sequence ID" value="ALN55361"/>
        <property type="gene ID" value="GLE_0002"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60881">
        <property type="protein sequence ID" value="ALN60881"/>
        <property type="gene ID" value="GLE_5540"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0002"/>
    <dbReference type="KEGG" id="lez:GLE_5540"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="222" mass="24800" checksum="2DC55260BB5281CB" modified="2016-02-17" version="1">MGHRHGVGAAARHRGRLGLRVDRDHAHQLVLDPGRGADRNLIQRAPGRQLGGRRRRRQRAGQDRGRAPIAGAGLAVGATARARGEDVVQRQAAGLFAHGQDQARVRRQRRQRGGIERGGQIPVTGLEQPSRRRRLRIPIRRRPHRRLRLQIARRRQAEHVLHRRHEDGALRQPAVIERSGAQHQGTDLAERIADAEHAAGREDAAAAVEPNLETLQRRAGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2003-10-01" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>Q7WZ06</accession>
    <name>Q7WZ06_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">GNAT family N-acetyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Putative acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_20895</name>
        <name evidence="3" type="ORF">GLE_4267</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2005" name="Appl. Environ. Microbiol." volume="71" first="261" last="269">
            <title>A clp gene homologue belonging to the Crp gene family globally regulates lytic enzyme production, antimicrobial activity, and biological control activity expressed by Lysobacter enzymogenes strain C3.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
                <person name="Reedy R.M."/>
                <person name="Palumbo J.D."/>
                <person name="Zhou J.M."/>
                <person name="Yuen G.Y."/>
            </authorList>
            <dbReference type="PubMed" id="15640196"/>
            <dbReference type="DOI" id="10.1128/AEM.71.1.261-269.2005"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AH013001">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948916.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4267"/>
    <dbReference type="EnsemblBacteria" id="ALN59608">
        <property type="protein sequence ID" value="ALN59608"/>
        <property type="gene ID" value="GLE_4267"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4267"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4205"/>
    <dbReference type="OMA" id="RIRAHQF"/>
    <dbReference type="OrthoDB" id="2055010at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="12"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="AAP83142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="153" mass="16856" checksum="9845D237C36B4E82" modified="2003-10-01" version="1">MGRAAPSDQTAPTVRLAETGDASDVAELLSQLGYPCTRDEAIERIAHLREDPRHYLLLAEIDGHACGLISSHTRYSLTHGAELARITALVVARSCHGQGIGRQLLREVERRARRDGVSRVEVTSNVSRTEAHEFYRRCGYADGSLKFVKTLGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAB9</accession>
    <name>A0A0S2DAB9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Bacteriophage related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0018</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0018"/>
    <dbReference type="EnsemblBacteria" id="ALN55377">
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        <property type="gene ID" value="GLE_0018"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0018"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.25"/>
    <dbReference type="OMA" id="NDRRYEV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021322">
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    </dbReference>
    <dbReference type="Pfam" id="PF11149">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="139" mass="15649" checksum="3F9431E9B12FE1D6" modified="2016-02-17" version="1">MTMRDLRAQWSELFENDPPVDQRRFLERRIAYRLQELAWSKHHAAELDANRARIALLVDKGKLPPRVRNGKPMPGSVLIRHFAGQDHVVTVKADGDFDYRGQSFTSLSALAKHITGTPWSGPVFFGLRSAGTKTKGGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAE2</accession>
    <name>A0A0S2DAE2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Type IV secretion system protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">VirB6 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">virB6</name>
        <name evidence="8" type="ORF">FE772_01175</name>
        <name evidence="7" type="ORF">GLE_0048</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945756.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0048"/>
    <dbReference type="EnsemblBacteria" id="ALN55407">
        <property type="protein sequence ID" value="ALN55407"/>
        <property type="gene ID" value="GLE_0048"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0048"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.55"/>
    <dbReference type="OrthoDB" id="1488773at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030255">
        <property type="term" value="P:protein secretion by the type IV secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007688">
        <property type="entry name" value="Conjugal_tfr_TrbL/VirB6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04610">
        <property type="entry name" value="TrbL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="317"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="332"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN55407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW24493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="353" mass="36854" checksum="0B64C09677D70473" modified="2016-02-17" version="1">MLDIISAGLSDSLHLLRAGIPDGVDSLGFFALFKDFLDGEIAEYSRNLLRRVGTLVAVGVTPLVTLWIIYQGYLRVTGQSHGSMAALKVEATRIVLIVTIAGASANFQDSIYKSMTDGVGQVINYAISGEDKATVYDNIDQALALMQLATSSIDMLDVGENQVALKKRDQASLVAGLGVGGPAVVGGCLLILNKFVIAMLLGVGPFFVLCLIFKQTEGLFKGWLNSLLGSLMAMAFLSVAVTLAMDVTLALAGGFWAAEGLSRLLGMGTASEGINSVVQMQGILGLVLTTLIMGAPPAAAMLFRGLLANFNPHSQFTGGGARSGDRAPSGYPQPPASSPPPPPPSGQQQVVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAE8</accession>
    <name>A0A0S2DAE8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Translocation and assembly module subunit TamA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Autotransporter assembly factor TamA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLE_0132</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TamA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0132"/>
    <dbReference type="EnsemblBacteria" id="ALN55491">
        <property type="protein sequence ID" value="ALN55491"/>
        <property type="gene ID" value="GLE_0132"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0132"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.135"/>
    <dbReference type="OMA" id="ALRYWNN"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010827">
        <property type="entry name" value="BamA/TamA_POTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039910">
        <property type="entry name" value="D15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035243">
        <property type="entry name" value="TamA_POTRA_Dom_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815">
        <property type="entry name" value="PTHR12815"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07244">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17243">
        <property type="entry name" value="POTRA_TamA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594856" description="Translocation and assembly module subunit TamA" evidence="9">
        <location>
            <begin position="42"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA_TamA_1" evidence="12">
        <location>
            <begin position="46"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="11">
        <location>
            <begin position="200"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="11">
        <location>
            <begin position="282"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="Omp85" evidence="10">
        <location>
            <begin position="386"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="110"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN55491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="682" mass="75028" checksum="620DB623669C9C7E" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAF3</accession>
    <name>A0A0S2DAF3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55498">
        <property type="protein sequence ID" value="ALN55498"/>
        <property type="gene ID" value="GLE_0139"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0139"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="138" mass="15391" checksum="0B6E0B2A3FEBAB4B" modified="2016-02-17" version="1">MVSTAMATSAFWARPEPAPPSPGSAAQTLALAAVPEPAYRAWPVLVGNARPRVRPGPARPAYGRNWLRGRERRCARRDTRTGPRPPRSASWRDSARPARRRPGRTRYRPPTQARRRSCVRCGRPKACRCSAPGRERCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAF4</accession>
    <name>A0A0S2DAF4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_01740</name>
        <name evidence="2" type="ORF">GLE_0173</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945848.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0173"/>
    <dbReference type="EnsemblBacteria" id="ALN55532">
        <property type="protein sequence ID" value="ALN55532"/>
        <property type="gene ID" value="GLE_0173"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0173"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.175"/>
    <dbReference type="OMA" id="GVRTSWG"/>
    <dbReference type="OrthoDB" id="1180629at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="321" mass="35152" checksum="141959730A9D2430" modified="2016-02-17" version="1">MTILVTGAAGFIGANVCRALRAQGRAVVGLDNYNDYYDPQIKRDRVAALCPDVDIRALDLTDRDGLAALFDEAGIERVVHLAAQAGVRYSLSNPHAYVDSNLVGFVNLLELCRHRGVQHLAYASSSSVYGDSATPPFSEDQRIDKPRSLYAATKAANELMAYTYAQLYGLRATGLRFFTVYGPWGRPDMAPLLFSRAVLAGRPIEVFNHGKMRRDFTYIDDIVAGVIGALDHPPQDAPPHRVFNLGNHTPVELERFIQVIEDAAGRPAQKIYKPMQPGDMVETMADTARAQAAFGFEPATSIETGLPGVVAWCRDYFGDNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAJ9</accession>
    <name>A0A0S2DAJ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter, ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_0149</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0149"/>
    <dbReference type="EnsemblBacteria" id="ALN55508">
        <property type="protein sequence ID" value="ALN55508"/>
        <property type="gene ID" value="GLE_0149"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0149"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.151"/>
    <dbReference type="OMA" id="QAFMHDP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="19"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="51"/>
            <end position="58"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN55508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="257" mass="27189" checksum="EA5A7B21DD416667" modified="2016-02-17" version="1">MPAGVDGPARGAAAMSPALELQGLHHRYDQHAVLHGIDLALAPGDFAALIGPNGSGKTTLLHCLAGLLRASAGRVLIGGHDLDRDPLAAKRALGFAVDPARLPPLLSGRECLRLFAGARGLDAIPEPTLALCATLSLQPMLDRRIGQYSLGTRQKLAIALGLLGEPPLLVLDEPLNGLDPLSAYALKRHLQELARERGVAVLLATHSLDVAERFITRAALLVDGRLRRQWDAGELDAIRADPARSLEQSMIDALAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAZ1</accession>
    <name>A0A0S2DAZ1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">GNAT family N-acetyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_12985</name>
        <name evidence="4" type="ORF">FE772_02110</name>
        <name evidence="2" type="ORF">GLE_0258</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000032">
        <property type="protein sequence ID" value="OPD63534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945908.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0258"/>
    <dbReference type="EnsemblBacteria" id="ALN55617">
        <property type="protein sequence ID" value="ALN55617"/>
        <property type="gene ID" value="GLE_0258"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63534">
        <property type="protein sequence ID" value="OPD63534"/>
        <property type="gene ID" value="BV903_12985"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0258"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.259"/>
    <dbReference type="OMA" id="DHRHQGK"/>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="20"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="188" mass="19962" checksum="AFA1D1669AE4D66E" modified="2016-02-17" version="1">MSLSPDSAAPADARAAPPAVRVGVVSPMLAPAVRMLQVAPEQLPFVGDTAYNLEQTRLDPHSEAMAVLVGERVVGFYRLDFSVDAIAGRALGEPSVGLRAYAIDRREQGRGYGTAAMRACVEDLRLRHPQRRLLALTVNVRNLAAIAAYRKAGFADTGELYHGGSAGPQHLMLLRLAPPSPSPTATAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBE8</accession>
    <name>A0A0S2DBE8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">OmpA family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">OmpA/MotB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_02945</name>
        <name evidence="5" type="ORF">GLE_0433</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW24782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946030.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0433"/>
    <dbReference type="EnsemblBacteria" id="ALN55791">
        <property type="protein sequence ID" value="ALN55791"/>
        <property type="gene ID" value="GLE_0433"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0433"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.430"/>
    <dbReference type="OMA" id="MKGEVHN"/>
    <dbReference type="OrthoDB" id="583204at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726641" evidence="3">
        <location>
            <begin position="30"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="4">
        <location>
            <begin position="167"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN55791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW24782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="282" mass="29462" checksum="294FA2391B33E235" modified="2016-02-17" version="1">MRGRTFFPSPARALPAIVLAAALASLACAASAQDAAPAAAPAPASASASAKPVIASGKVPDESSKQAVLAKLRELYGNERVIDRIEVSSGIVTPPNWRQNVVNMLGPDLQQVSDGKLEVNGNAVRVSGNVANELQRQQIVSGLSTRINNPTYSVDGRLLRVAGGAQQSLLDNVLANRIVEFESGSATLTPKGELILDEMAAAMKRIGNKRVLIVGHTDAAGRRESNLALSLARADSVKRYLQAHGVNGALLGVQGAGPDQPVADNATAEGRARNRRIAFKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBJ2</accession>
    <name>A0A0S2DBJ2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">AI-2E family transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_03150</name>
        <name evidence="7" type="ORF">GLE_0481</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0481"/>
    <dbReference type="EnsemblBacteria" id="ALN55839">
        <property type="protein sequence ID" value="ALN55839"/>
        <property type="gene ID" value="GLE_0481"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0481"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.477"/>
    <dbReference type="OMA" id="HEAENPG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="320"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN55839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW24819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="356" mass="38080" checksum="DC0675A7C85BF812" modified="2016-02-17" version="1">MEPHVDPAAAPGPGVAPTLAATSLKAPPARIAAWLFAAAALFLVLKFGLLSALLSGLLVFQLVHTLARLADRRIKGQWARLFAVMLIAALVVGGLTLATLGLIAFFRADTGGEQALLARLMDVIDASRAQVPAWAQPYLPEDLSDLQRALSAWLDEHRGELSLVGAEAVQLGARLVIGMVLGAMIALQDELQPLKLGPLGSEMLARAARLSDAFRRVVFAQIKISALNTAFTAVFLLIVLPLFGVHLPMAKTLVVLTFVVGLLPVVGNLISNTLITVAGLSVSVYVAAAALLYLVLIHKLEYFLNARIVGGEIQARAWELLLAMLMMEALFGMPGLVAAPIYYAYLKRELVEQGWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBQ5</accession>
    <name>A0A0S2DBQ5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0592</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55950">
        <property type="protein sequence ID" value="ALN55950"/>
        <property type="gene ID" value="GLE_0592"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0592"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.584"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="38" mass="4370" checksum="B615F7BA3B7378C9" modified="2016-02-17" version="1">MRLARIGKRAANFFPRARTAEKSHVRMTQCAVHKKCAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC30</accession>
    <name>A0A0S2DC30_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Iron-sulfur cluster insertion protein ErpA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">erpA</name>
        <name evidence="8" type="ORF">BV903_22505</name>
        <name evidence="10" type="ORF">D9T17_23510</name>
        <name evidence="9" type="ORF">FE772_04330</name>
        <name evidence="7" type="ORF">GLE_0728</name>
    </gene>
    <organism evidence="7 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 11">C3</strain>
        </source>
    </reference>
    <reference evidence="8 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">OH11</strain>
        </source>
    </reference>
    <reference evidence="9 14" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for insertion of 4Fe-4S clusters for at least IspG.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>iron-sulfur cluster</name>
            <dbReference type="ChEBI" id="CHEBI:30408"/>
        </cofactor>
        <text evidence="5">Binds 1 iron-sulfur cluster per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the HesB/IscA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000075">
        <property type="protein sequence ID" value="OPD61672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000059">
        <property type="protein sequence ID" value="ROU04525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946254.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000059.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0728"/>
    <dbReference type="EnsemblBacteria" id="ALN56086">
        <property type="protein sequence ID" value="ALN56086"/>
        <property type="gene ID" value="GLE_0728"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61672">
        <property type="protein sequence ID" value="OPD61672"/>
        <property type="gene ID" value="BV903_22505"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0728"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.716"/>
    <dbReference type="OMA" id="YQLYFDE"/>
    <dbReference type="OrthoDB" id="1891602at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01380">
        <property type="entry name" value="Fe_S_insert_ErpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="FeS_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="FeS_cluster_insertion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017870">
        <property type="entry name" value="FeS_cluster_insertion_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023063">
        <property type="entry name" value="FeS_cluster_insertion_RrpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="SSF89360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00049">
        <property type="entry name" value="TIGR00049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01152">
        <property type="entry name" value="HESB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-S_biosyn" evidence="6">
        <location>
            <begin position="19"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>iron-sulfur cluster</name>
            <dbReference type="ChEBI" id="CHEBI:30408"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>iron-sulfur cluster</name>
            <dbReference type="ChEBI" id="CHEBI:30408"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>iron-sulfur cluster</name>
            <dbReference type="ChEBI" id="CHEBI:30408"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN56086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD61672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW25013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROU04525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="124" mass="13459" checksum="701A224E425695DC" modified="2016-02-17" version="1">MEIATLNSAPDYQSLERPLQFTSSAAHKVRELIAEEGNDALKLRVYIQGGGCSGFQYGFEFDEQQGEDDLAVQTDGVTLLVDPLSLQYLMGAEVDYTESLHGSQFVIRNPNAKTTCGCGSSFGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCD0</accession>
    <name>A0A0S2DCD0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56008">
        <property type="protein sequence ID" value="ALN56008"/>
        <property type="gene ID" value="GLE_0650"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0650"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.639"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="49" mass="5305" checksum="225E66F4242172AE" modified="2016-02-17" version="1">MFRNIYRECAFFVISIRANGNQDARHAAACGGIEGDARAAIPILSRSPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCK1</accession>
    <name>A0A0S2DCK1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ACR family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">DUF192 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_23975</name>
        <name evidence="4" type="ORF">FE772_05030</name>
        <name evidence="2" type="ORF">GLE_0876</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000088">
        <property type="protein sequence ID" value="OPD61394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946363.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000088.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56234">
        <property type="protein sequence ID" value="ALN56234"/>
        <property type="gene ID" value="GLE_0876"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61394">
        <property type="protein sequence ID" value="OPD61394"/>
        <property type="gene ID" value="BV903_23975"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0876"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.865"/>
    <dbReference type="OMA" id="TMWMKNT"/>
    <dbReference type="OrthoDB" id="1934378at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003795">
        <property type="entry name" value="DUF192"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038695">
        <property type="entry name" value="Saro_0823-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37953">
        <property type="entry name" value="PTHR37953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02643">
        <property type="entry name" value="DUF192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594831" evidence="1">
        <location>
            <begin position="20"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="147" mass="16240" checksum="FA43A3101FE1E0E2" modified="2016-02-17" version="1">MSKASALLVCCLLGLAGCAASEGRSWVEVGGERFQVEVAKTREERARGLMFRDRMPAGDGMVFVHDSEDLQAYWMKNTKIPLDILYFDARRRLVSQQRNVPPCSAGDRCPPYPSEAPAKYVLELNGGQAEKLKLETGAEMKFGPGIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCU6</accession>
    <name>A0A0S2DCU6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Iron-sulfur cluster-binding protein, Rieske family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_1003</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1003"/>
    <dbReference type="EnsemblBacteria" id="ALN56361">
        <property type="protein sequence ID" value="ALN56361"/>
        <property type="gene ID" value="GLE_1003"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1003"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.991"/>
    <dbReference type="OMA" id="RCPHAGL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="4">
        <location>
            <begin position="16"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="122" mass="12694" checksum="8F833379B6577610" modified="2016-02-17" version="1">MRTSLNASGDDGSGAQPLIELERLADGGFAEVEATIDGDAESLLLYRDGDAVRAWLNICPHAGRRLDWAPGQFLKSKDGLLVCAAHGASFELGGGECVAGPCRGEALRAVAVDVRDGGVWLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD09</accession>
    <name>A0A0S2DD09_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Thiamine-phosphate synthase</fullName>
            <shortName evidence="8">TP synthase</shortName>
            <shortName evidence="8">TPS</shortName>
            <ecNumber evidence="8">2.5.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Thiamine-phosphate pyrophosphorylase</fullName>
            <shortName evidence="8">TMP pyrophosphorylase</shortName>
            <shortName evidence="8">TMP-PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 13" type="primary">thiE</name>
        <name evidence="13" type="ORF">GLE_0874</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 9">
            <text>2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = CO2 + diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:47848"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62890"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 8 9">
            <text>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = CO2 + diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:47844"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8 9">
            <text>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 4-methyl-5-(2-phosphooxyethyl)-thiazole + H(+) = diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:22328"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:58296"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 8 10">Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine phosphate from 4-amino-2-methyl-5-diphosphomethylpyrimidine and 4-methyl-5-(2-phosphoethyl)-thiazole: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the thiamine-phosphate synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.3" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946362.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0874"/>
    <dbReference type="EnsemblBacteria" id="ALN56232">
        <property type="protein sequence ID" value="ALN56232"/>
        <property type="gene ID" value="GLE_0874"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0874"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.863"/>
    <dbReference type="OMA" id="ITAFQFR"/>
    <dbReference type="OrthoDB" id="1558094at2"/>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00141"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004789">
        <property type="term" value="F:thiamine-phosphate diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00564">
        <property type="entry name" value="TMP_TenI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00097">
        <property type="entry name" value="TMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036206">
        <property type="entry name" value="ThiamineP_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022998">
        <property type="entry name" value="ThiamineP_synth_TenI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034291">
        <property type="entry name" value="TMP_synthase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02581">
        <property type="entry name" value="TMP-TENI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51391">
        <property type="entry name" value="SSF51391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00693">
        <property type="entry name" value="thiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8 9" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="5 8 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TMP-TENI" evidence="12">
        <location>
            <begin position="24"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="HMP-PP binding" evidence="8">
        <location>
            <begin position="53"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="THZ-P binding" evidence="8">
        <location>
            <begin position="151"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="THZ-P binding" evidence="8">
        <location>
            <begin position="200"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN56232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="226" mass="23429" checksum="E42585D316E1230A" modified="2016-02-17" version="1">MPQSRPPRPFPPPPGPPQAPARGLYAITPDEADTARLLARAATVLDAGAAWLQYRNKHADAGLRREQAQALLPLCRARAVPLIVNDDWRLAARIGADGAHLGEDDGELAAARAALGPDAILGASCYADIALARAAAAQGASYVAFGAFFPSPTKPNARRAAPELLRQAAALGLPRVAIGGITPDNARSLVRAGADLLAVISGVFDAPDPAAAARAYLSCFEDPIHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD38</accession>
    <name>A0A0S2DD38_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946525.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56459">
        <property type="protein sequence ID" value="ALN56459"/>
        <property type="gene ID" value="GLE_1101"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1101"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1088"/>
    <dbReference type="OMA" id="VAPWRHA"/>
    <dbReference type="OrthoDB" id="2029387at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="222" mass="23115" checksum="E86C8A4420849E2C" modified="2016-02-17" version="1">MNENELHPRGPERAGEGELPDTLRWQLRALRRDQPPARDLWAGIAARLGEQAPAGADGAVAAEPPSAGAAAAAARPAPEPAAIVALPRPAGARRNWMAPLALAASVAALAVGIGAHFHAQGPAAPAADAVAGRAVAAQAAAPSLVQREAQGLTLQYQAALREVEPVSSATVAMKPAFDELDRNAALILDALSHDPDSRMLLEQLRRTYARRLALAQRLVAYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD99</accession>
    <name>A0A0S2DD99_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1181</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56539">
        <property type="protein sequence ID" value="ALN56539"/>
        <property type="gene ID" value="GLE_1181"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1181"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1166"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="304" mass="33129" checksum="FC43E8BF25C9363E" modified="2016-02-17" version="1">MLAPDASQWPQRHMFGTLAHEIGHDRYNTGSIPFIGRSADEYVEYRAALEAKAIFNAFPIFKELENVEAFKGGKPFGSIGYLNEVELGARYGDWRAGRLDETAVVERIAAKVADAPYSLNNPPADMNRDGLITHRDAYLRDYAAYIEPKLARAHSGPGGDPRDPGHPDSGLLEHLRGQVRALDRQSGKTWDDRSERLTASALAMAKEKGFTLEDAPLLAFNKASGPLGEGEILHLFRAGPNASPDPYANRVHMPTAQALSVPAEQRYQQVGAISAAQSEQAPIMHPEPARDPGDPGKNGPKFAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDD2</accession>
    <name>A0A0S2DDD2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1221</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1221"/>
    <dbReference type="EnsemblBacteria" id="ALN56578">
        <property type="protein sequence ID" value="ALN56578"/>
        <property type="gene ID" value="GLE_1221"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1221"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1206"/>
    <dbReference type="OMA" id="RKDPQQI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018642">
        <property type="entry name" value="DUF2066"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09839">
        <property type="entry name" value="DUF2066"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="349" mass="36720" checksum="D04F5BB38EA9AC04" modified="2016-02-17" version="1">MAAALLASFAASAQRVEGDRAQADGAYSAEVPVGGQSENERNGAMARALAQVLSKMSGDRAAASRPGVGQELRRAKDYATGYDYRQDEGVSQVTGAPTFQTTLVVSFDQEKVDNLAATLGLPIWPQPRPKPVLWLAIDDGSGPRLVGLAQANAARAALNRAVERGYRLGLPSGSAAEQASVGAIWRGDAAAVARASARYSPPMQLIGKLYRVKTGGWKGDWTFVDGGKVLGSWNSADLDARKVMAGGADGAADALMKRYAKRSVAGTPGTYRVVFTGVRSADDYIRLAGYLQGLAVVRKIVPVRATPESVEFDLDLLSGLPGFKRMTDAGGTLVGLEGLEGQPPVFQLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDN7</accession>
    <name>A0A0S2DDN7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BtrU-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1287</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1287"/>
    <dbReference type="EnsemblBacteria" id="ALN56644">
        <property type="protein sequence ID" value="ALN56644"/>
        <property type="gene ID" value="GLE_1287"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1287"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1270"/>
    <dbReference type="OMA" id="QEPKHYG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020941">
        <property type="entry name" value="SUFU-like_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037181">
        <property type="entry name" value="SUFU_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007768">
        <property type="entry name" value="Suppressor_of_fused"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017429">
        <property type="entry name" value="Suppressor_of_fused_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10928">
        <property type="entry name" value="PTHR10928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05076">
        <property type="entry name" value="SUFU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038192">
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="73"/>
            <end position="222"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="357" mass="39102" checksum="A3970F55D9567AB3" modified="2016-02-17" version="1">MQYTSPSAMAASESEHGPAHRLDTHGSDAGAPGWDAINHALNRVYPRQSPWHSSAPAGDAAPLPGISAYKRITPLPHWHFVTYGFSELFDKRSDDAEISGYGFELTFRLANPDDADEPPRWALNFLQNLARYVFESGHGFHAGHYLSAGGPIAADSDSAIRALAFVHDPELAPIDSDNGRVEFLQIVGLTNEEEFALKRWSTLKVLEVFHDYLPLWITDLERGSLLADPEIAARLAGGSAREGSSVGTIYADHVDWEQRKRLLRAPTTVLSLSARQVGELLALLPLRLPFGNAFGVVGPERRAVFEPAVRGNEAEVADGALHLRLDERAVRSLVSRLRAQAGIYEVDGFAALQVEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDT4</accession>
    <name>A0A0S2DDT4_LYSEN</name>
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        <submittedName>
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        </submittedName>
    </protein>
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        <name evidence="8" type="ORF">FE772_07510</name>
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        <name type="scientific">Lysobacter enzymogenes</name>
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            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Xanthomonadaceae</taxon>
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        </lineage>
    </organism>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
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        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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    </comment>
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    </dbReference>
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        <property type="protein sequence ID" value="QCW25532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN56779">
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        <property type="gene ID" value="GLE_1422"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1422"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1401"/>
    <dbReference type="OMA" id="IGMASPM"/>
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    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
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        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
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            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
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            <end position="300"/>
        </location>
    </feature>
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        <location>
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            <end position="351"/>
        </location>
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        </location>
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            <end position="419"/>
        </location>
    </feature>
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        <location>
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        </location>
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        </location>
    </feature>
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        <location>
            <begin position="39"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN56779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW25532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="566" mass="59610" checksum="AB36F03A6ED0258D" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDV6</accession>
    <name>A0A0S2DDV6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MATE efflux family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">MATE family efflux transporter</fullName>
        </submittedName>
    </protein>
    <gene>
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        <name evidence="2" type="ORF">GLE_1370</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56727">
        <property type="protein sequence ID" value="ALN56727"/>
        <property type="gene ID" value="GLE_1370"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1370"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1352"/>
    <dbReference type="OMA" id="DYKHEMV"/>
    <dbReference type="OrthoDB" id="1415498at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
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            <end position="70"/>
        </location>
    </feature>
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            <end position="108"/>
        </location>
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            <end position="145"/>
        </location>
    </feature>
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        </location>
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        </location>
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        </location>
    </feature>
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            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN56727.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW25494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="479" mass="52180" checksum="EFE081E94A2B000D" modified="2016-02-17" version="1">MTHDSPAADPPHAAEAQPPQSLWRELRDAVRGTDADYTKIPLRRAVFLLAVPMVLELVLESTFAVVDIFFVSKLGPSAVATVGLTESYLFLLYAVAMGLAMAVTAVVARRIGEGKPEEAAATAVQAILIALLVSVPPALAGIFYAQDLLRLMGADAWSIEHGYRYTQWMLGANVVIVLLFVINAIFRGAGDAAISMRVLWLSNGLNIVLCPLLIFGPGPFPAWGIEGAAIATCIGRGCGVLYQLWVLFRGGKHIRVTAAQLVWQGAMLWNIVRTSLGGVGQMIVAMTAWIFLMRILATIGSEAVAGATIAIRVMMFTMMPAWGMSNAAATLVGQNLGAGHADRAEAAVWHIGWYNMGYLVLVSVLFFAFPQQLVGIFSADPEVVKVGAEWLRILSYSFFIYGWWMVTVQAFNGAGDTITPTKINVVFFWLIQIPLSYWLAIQLGWKELGVFWGVFVSETSVGAFTLWLFTRGKWKQAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE01</accession>
    <name>A0A0S2DE01_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase S8</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Peptidase, families S8 and S53</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FE772_07490</name>
        <name evidence="8" type="ORF">GLE_1418</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW25529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946761.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1418"/>
    <dbReference type="EnsemblBacteria" id="ALN56775">
        <property type="protein sequence ID" value="ALN56775"/>
        <property type="gene ID" value="GLE_1418"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1418"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1397"/>
    <dbReference type="OMA" id="ESVENDM"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07496">
        <property type="entry name" value="Peptidases_S8_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034176">
        <property type="entry name" value="Peptidases_S8_13"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242180" evidence="6">
        <location>
            <begin position="30"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="7">
        <location>
            <begin position="162"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN56775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW25529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="486" mass="48873" checksum="AD5D0B7FA6996E26" modified="2016-02-17" version="1">MGNRHPRSNALSLATALVLGACAFAPAYAGGKANLASLEDGSRSFGRFVVTYRSGTAPRRDAAALERSLGNAASALGLNTLQRLRRTATGSDVVVSPRPLSRAEATALLHTIAADPNVESVENDMRMVPYWTPNDSRFREQFGFGSGAGGIRATTAWDVARGAGTVVAVIDTGIASHSDLNGNLVGGYDFISALSGAEAQQFGAFFIAADGNARDANPADPGDWNDNPNACRTGNSSWHGTHVAGTVAAVTNNAKGVAGTAPAAKVVPVRVLGRCGGFSSDIADAITWASGGAVPGVPANPNPADVINMSLGGSAPGACPQSYKNAIVGAAQRGSIVVVAAGNDDANASTAVNSDGQPVGYTMTNCGTVISVGATTSSGGRSSFSNFGPGVDIAAPGSGILSTVNNGLRGPTTEAYKAYDGTSMATPHVAGVAALVQSVARTPLTQEQMRTLLKNTARPFPVSPGAKPIGAGIVNADAAVKAAKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE90</accession>
    <name>A0A0S2DE90_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Patatin-like phospholipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_1264</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56621">
        <property type="protein sequence ID" value="ALN56621"/>
        <property type="gene ID" value="GLE_1264"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1264"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1248"/>
    <dbReference type="OMA" id="YFDNTRQ"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021095">
        <property type="entry name" value="DUF3734"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12536">
        <property type="entry name" value="DUF3734"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="4">
        <location>
            <begin position="124"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="2">
        <location>
            <begin position="128"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="155"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="330"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="34"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="95"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="496" mass="54436" checksum="B1E5E0D0B7000C16" modified="2016-02-17" version="1">MPAPRSRKTAAGASRAAAKRNPRPAASAGRDPKPVAPAKRDPKPATPAKRDPPSKTPPRKEPPKREPGAAARASAPPTRARRAAGPAPATPRQARRAEATERAARESAQRVHDAAPALPENIALVLQGGGALGAYQAGVYQGLFEAGIAPNWIAGISIGAFNTAIIAGNPPDKRMAALREFWDTISRPNIFPATTFGQEARFDGIDADTRAWLDTWEAWRALIEGQRGFYQPRAWLGPDPSLWAGGQPGPAAASFYDTSPMIATLERLVDFDRLNDGGIRVSVGAVNVRTGNLEYFDNTQMRLDARHILASGALPPAFPAIEIDGEFYWDGGLVSNTPLSQVLTASPRRDTLVFQVDLWNARGEPPQNLLDVAERQKEIQYSSRTRLITDTQRVFQHYRRLLRELLEEIPEDVRASNPWAQHAAELACDRRYSVIHLIYRDRAKIGHFKDYQFGRVAMREHWLSGQGDIARALSHPDWLQLPQGESAFVAHDATAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DER4</accession>
    <name>A0A0S2DER4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1442</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56799">
        <property type="protein sequence ID" value="ALN56799"/>
        <property type="gene ID" value="GLE_1442"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1442"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1422"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="52" mass="5189" checksum="C1B16DE6A843C942" modified="2016-02-17" version="1">MASIVPNIGTNLAHPAGAAPPSCPSRRRAVRLAARSRNRVGRGGGSVAGLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEY7</accession>
    <name>A0A0S2DEY7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Exodeoxyribonuclease 7 large subunit</fullName>
            <ecNumber evidence="5">3.1.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Exodeoxyribonuclease VII large subunit</fullName>
            <shortName evidence="5">Exonuclease VII large subunit</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">xseA</name>
        <name evidence="10" type="ORF">FE772_08985</name>
        <name evidence="9" type="ORF">GLE_1745</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.11.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterooligomer composed of large and small subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the XseA family.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.6" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947021.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1745"/>
    <dbReference type="EnsemblBacteria" id="ALN57100">
        <property type="protein sequence ID" value="ALN57100"/>
        <property type="gene ID" value="GLE_1745"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1745"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1721"/>
    <dbReference type="OMA" id="WPAVRFE"/>
    <dbReference type="OrthoDB" id="1371775at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009318">
        <property type="term" value="C:exodeoxyribonuclease VII complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008855">
        <property type="term" value="F:exodeoxyribonuclease VII activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04489">
        <property type="entry name" value="ExoVII_LU_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00378">
        <property type="entry name" value="Exonuc_7_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003753">
        <property type="entry name" value="Exonuc_VII_L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020579">
        <property type="entry name" value="Exonuc_VII_lsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025824">
        <property type="entry name" value="OB-fold_nuc-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30008">
        <property type="entry name" value="PTHR30008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02601">
        <property type="entry name" value="Exonuc_VII_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13742">
        <property type="entry name" value="tRNA_anti_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00237">
        <property type="entry name" value="xseA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_anti_2" evidence="8">
        <location>
            <begin position="13"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="Exonuc_VII_L" evidence="7">
        <location>
            <begin position="126"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN57100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW25780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="447" mass="50014" checksum="8AC2BB541046B8A7" modified="2016-02-17" version="1">MPPSSPDEVLTPSQLNTLARDLLEDTFPLIWVEGELGNLSRPSSGHLYMTLKDARAQVRCAMFKPKSSWLKFVPREGLRVLARGRLTLYEARGDYQLVLDHMEEAGEGALRRAFEELKARLAAEGLFDRERKRELPRFPERIAIITSPSGAAVRDVLSVLGRRFPLAQAEVLPVPVQGDGAAEKIVAMLQRAQAAQRYDVIVLARGGGSLEDLWAFNDERLARAIAASDVPVVSAIGHETDFTLADFAADVRAPTPSVAAELLVPQREDLLHRLRVLEARLHNLHSQRLRQAMQRTDRAGLRLNALRPQARLAALRNRQQDALRRLEQAWRLRVERETARLRHSDAVLRAHHPQRRIARLRERLAALAPRPRAALARRLHGDALRLRGLARSLAAVSPLATVARGYAIVQHDDGRVVRSVLDAAPGDRLSARVQDGQIRVRVEPRED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF01</accession>
    <name>A0A0S2DF01_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoglycerate mutase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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        </lineage>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946925.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1617"/>
    <dbReference type="EnsemblBacteria" id="ALN56974">
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        <property type="gene ID" value="GLE_1617"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1617"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1598"/>
    <dbReference type="OMA" id="TQYQRTQ"/>
    <dbReference type="OrthoDB" id="1122642at2"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
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        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594755" evidence="1">
        <location>
            <begin position="26"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="174" mass="18483" checksum="62780DD9588F8944" modified="2016-02-17" version="1">MDRIAAFAFAVAAATTLAGCASAPAAPSSPAARYILVRHAEKASDDPRDPTLSAAGLERAQRLAARLREEPLGAVYVTGYRRTLQTGEPAARGHGLTPIVYDAKSPAAQFAAQLRRERPAGATLVVGHSNTAPDIAAALCACAVEPMPETEYDRRMIVDFDAQGRATLRIERDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF26</accession>
    <name>A0A0S2DF26_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metallo-beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1667</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="34"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="237" mass="26543" checksum="447407D80A364BF4" modified="2016-02-17" version="1">MELGSAMATLERDGEPWLTIDCGGEGLTAFLRHYGRMPEAVFLTHAHMDHIAGFERLFVAHYFDPDRRGKVRLYIPAPLVPLLQQRVADYPNVLAEGGVNFWDAFQLVPVSGHFWHRGVRMEAFPVRHHWPDSAFGLRLRGSAVWTGDTRPIPEMLARFADEGELIAHDCALHGNPSHSGIEDLEREYPRALLQRCVLYHYASREEGDALAARGYRVGRPGEAIDLADPTAAQVPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF37</accession>
    <name>A0A0S2DF37_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1783</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57137">
        <property type="protein sequence ID" value="ALN57137"/>
        <property type="gene ID" value="GLE_1783"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1783"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1757"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="41" mass="4848" checksum="53DE223B34B283DD" modified="2016-02-17" version="1">MSRDDKPPSKAFVRKRPSYFLLSARQKKVAKEKRLFKGKSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFC5</accession>
    <name>A0A0S2DFC5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1782</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57136">
        <property type="protein sequence ID" value="ALN57136"/>
        <property type="gene ID" value="GLE_1782"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1782"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1756"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="47" mass="5208" checksum="59DD6434026B7B7B" modified="2016-02-17" version="1">MDLRLSSRARTRKDEPHRGTPPVGAAQAAXXXXXXXDRHSGESRNPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFT6</accession>
    <name>A0A0S2DFT6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TraH protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Type IV secretion system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">traH</name>
        <name evidence="8" type="ORF">FE772_10430</name>
        <name evidence="7" type="ORF">GLE_2059</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947249.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2059"/>
    <dbReference type="EnsemblBacteria" id="ALN57409">
        <property type="protein sequence ID" value="ALN57409"/>
        <property type="gene ID" value="GLE_2059"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2059"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2024"/>
    <dbReference type="OMA" id="AMFFQGT"/>
    <dbReference type="OrthoDB" id="1488773at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030255">
        <property type="term" value="P:protein secretion by the type IV secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007688">
        <property type="entry name" value="Conjugal_tfr_TrbL/VirB6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04610">
        <property type="entry name" value="TrbL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="310"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="310"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW26026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="365" mass="39788" checksum="123894EE55F4E975" modified="2016-02-17" version="1">MQLFAVLADWLAPLAQGIGDYAYFKLISAYFDHKIGQFGLGLMKRTMAWTSQIALILTTLWIMLSGYRIVTGQSREPMMGLVVNAARIAFIVALATTMSFGGASLHRFFTKDLDREIHELFTDDDSSSADAIDKNLAYMQIAMGAIDVVQVPDDNPKLQKEKERALVFAGVGTAAPPMVAGAMLLLYKFTLALFIGLGPIFILCLMFDQTKDLFRKWLMYGIGNLFSMAMLSVVVSMTMELMAKVAVVLWVAKATRIMGTATEGLTTQAMQQGGIGLLMTTVIVTVPPAAAMFFQGTAANFNYNTAFGSSAKDRGSQQGANQTQQQPPVVTDAPSSPARHPYQLPLDSSSDVGNRTKKYDEVKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFZ9</accession>
    <name>A0A0S2DFZ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2192</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947353.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2192"/>
    <dbReference type="EnsemblBacteria" id="ALN57541">
        <property type="protein sequence ID" value="ALN57541"/>
        <property type="gene ID" value="GLE_2192"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2192"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2154"/>
    <dbReference type="OMA" id="LYPRNRQ"/>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="302" mass="33615" checksum="1CF73B2A0D2D765B" modified="2016-02-17" version="1">MDRLDTLRLFVRIVELGSFTRAAAVLDLPRATATHAIKQLEARLGARLLERTTRQVRPTLDGQAYYERCVHVLAELDDADAALAQLAGDPRGTLRIDLHGIHAVGLVLPRIDEFHARYPRIELEISSGDRLVDLVREGIDCVVRSGVPRDSSLVARRIATMPEVVCASPEYLQRHGVPRHPDELAAHRAVGFFASDRDLRYPFELTVDGALREYRLDSWINVNDAACYAAAALRGCGLIQLPRHGVERYLDEGRLVEVLGEYASPGVPAWAMYPRHRQLSPRVRAFVDWVAGVFADKFGAPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG30</accession>
    <name>A0A0S2DG30_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 8">Transcription elongation factor GreA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Transcript cleavage factor GreA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">greA</name>
        <name evidence="12" type="ORF">BV903_23125</name>
        <name evidence="14" type="ORF">D9T17_13655</name>
        <name evidence="13" type="ORF">FE772_11290</name>
        <name evidence="11" type="ORF">GLE_2240</name>
    </gene>
    <organism evidence="11 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 15">C3</strain>
        </source>
    </reference>
    <reference evidence="12 16" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 16">B25</strain>
        </source>
    </reference>
    <reference evidence="14 17" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">OH11</strain>
        </source>
    </reference>
    <reference evidence="13 18" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 18">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7 8">Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the GreA/GreB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000078">
        <property type="protein sequence ID" value="OPD61557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000033">
        <property type="protein sequence ID" value="ROU06492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947391.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2240"/>
    <dbReference type="EnsemblBacteria" id="ALN57589">
        <property type="protein sequence ID" value="ALN57589"/>
        <property type="gene ID" value="GLE_2240"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61557">
        <property type="protein sequence ID" value="OPD61557"/>
        <property type="gene ID" value="BV903_23125"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2240"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2205"/>
    <dbReference type="OMA" id="TWLTQEA"/>
    <dbReference type="OrthoDB" id="1536415at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00105">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036953">
        <property type="entry name" value="GreA/GreB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018151">
        <property type="entry name" value="TF_GreA/GreB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006359">
        <property type="entry name" value="Tscrpt_elong_fac_GreA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028624">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001437">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023459">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022691">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036805">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30437">
        <property type="entry name" value="PTHR30437"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01272">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03449">
        <property type="entry name" value="GreA_GreB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006092">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46557">
        <property type="entry name" value="SSF46557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01462">
        <property type="entry name" value="greA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00829">
        <property type="entry name" value="GREAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="GreA_GreB_N" evidence="10">
        <location>
            <begin position="4"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="GreA_GreB" evidence="9">
        <location>
            <begin position="83"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN57589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OPD61557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW26168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROU06492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="158" mass="17036" checksum="388B6D7227AA2875" modified="2016-02-17" version="1">MRAPITAKGALRLRAELEELKSVKRPAVINAIAEARAHGDLKENAEYHAAREQQGFIEGRIKQLEAELSHAQIIDTSTLNAGSKVVFGANVELADTETDEEKRYQIVGDLEADIKLGLIAISSPVARALIGKNEGDTVVIEAPGGTREYEIVGVSYEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGD6</accession>
    <name>A0A0S2DGD6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Linear gramicidin synthetase subunit C</fullName>
            <ecNumber evidence="7">5.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_2104</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.-" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947283.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2104"/>
    <dbReference type="EnsemblBacteria" id="ALN57454">
        <property type="protein sequence ID" value="ALN57454"/>
        <property type="gene ID" value="GLE_2104"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2104"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2068"/>
    <dbReference type="OMA" id="WEPVPSV"/>
    <dbReference type="Proteomes" id="UP000061569">
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="P:organic substance biosynthetic process"/>
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        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
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        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
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        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
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        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="710"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="2241"/>
            <end position="2315"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="3779"/>
            <end position="3856"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="4837"/>
            <end position="4912"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="5880"/>
            <end position="5955"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="6936"/>
            <end position="7010"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2770"/>
            <end position="2789"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="745"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="2276"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="3816"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="5915"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="6971"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="7518" mass="820325" checksum="C8FC4635650FA4D2" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGG9</accession>
    <name>A0A0S2DGG9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DUF3413 domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Sulfatase</fullName>
            <ecNumber evidence="4">3.1.6.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_10860</name>
        <name evidence="4" type="ORF">GLE_2152</name>
    </gene>
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        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.6.-" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW26097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN57502">
        <property type="protein sequence ID" value="ALN57502"/>
        <property type="gene ID" value="GLE_2152"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2152"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2115"/>
    <dbReference type="OMA" id="YGIPGTY"/>
    <dbReference type="OrthoDB" id="1067869at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
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        <property type="entry name" value="Sulfatase_N"/>
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        <property type="entry name" value="YejM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024588">
        <property type="entry name" value="YejM_N"/>
    </dbReference>
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        <property type="entry name" value="DUF3413"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Mmb_sulf_HI0842"/>
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    </dbReference>
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        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
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            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="101"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3413" evidence="3">
        <location>
            <begin position="12"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase" evidence="2">
        <location>
            <begin position="257"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="619" mass="69309" checksum="33436357FF26C2BB" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGJ6</accession>
    <name>A0A0S2DGJ6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Spermidine/putrescine import ATP-binding protein PotA</fullName>
            <ecNumber evidence="8">7.6.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">potG</name>
        <name evidence="8" type="synonym">potA</name>
        <name evidence="11" type="ORF">BV903_02025</name>
        <name evidence="12" type="ORF">FE772_11740</name>
        <name evidence="10" type="ORF">GLE_2342</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">C3</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.11" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000004">
        <property type="protein sequence ID" value="OPD65567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947465.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2342"/>
    <dbReference type="EnsemblBacteria" id="ALN57691">
        <property type="protein sequence ID" value="ALN57691"/>
        <property type="gene ID" value="GLE_2342"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65567">
        <property type="protein sequence ID" value="OPD65567"/>
        <property type="gene ID" value="BV903_02025"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2342"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2304"/>
    <dbReference type="OMA" id="IHVMRFN"/>
    <dbReference type="OrthoDB" id="1200451at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015417">
        <property type="term" value="F:ABC-type polyamine transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005893">
        <property type="entry name" value="Sp_pt_ABC_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_1"/>
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    </dbReference>
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        <ligand>
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        <source>
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        <source>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="384" mass="42079" checksum="62CEBAF1326D6F70" modified="2016-02-17" version="1">MSVPARSPALEPWRDPAAQPFVRIEGVTKTFGKVYACDDISLDVYRGEFFALLGGSGSGKSTLLRVLAGFESPDRGRVLIDGIDVTDLPPYERPVNMMFQSYALFPHMSVAQNIAFGLKHSSGGARPGAGEIRDRVQQMLELVRMPQLGNRKPDQLSGGQRQRVALARALAKQPKLLLLDEPLGALDKKLREHTQFELVSIQERVGTTFIMVTHDQEEAMTMSSRIAVMDAGRIVQVSTPAVLYEYPSTRFVAEFIGGINLLEGRVLGHDGDGDLRIQCDGVGGELLARHPDPLPEGTAVGIAVRPEKIDVHETKPEGFDNAVMGKVRDIAYLGDVSIYHVQTEAGAVLRVQETHVARSSQPHYDWDDTLWLSWDAASAVVLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
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    </dbReference>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57391.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="58" mass="5886" checksum="3C21B1DB45427710" modified="2016-02-17" version="1">MAGGGSAVVARGFASQEAALASGLRRASPQSGRNVPCRPARRPLRSAGALCQCTGFVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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            <dbReference type="EMBL" id="ALN57566.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="54" mass="5750" checksum="041A19253DFAD4F2" modified="2016-02-17" version="1">MGKRSVAAMFAVPVGRGGGWFAVNLREGFSPDVFRPGCGECFEDVGELSGERRG</sequence>
</entry>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
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    </dbReference>
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            <end position="251"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="322" mass="35855" checksum="E83F918302421A41" modified="2016-02-17" version="1">MDRIASGALSALTPQSPAQWQTAPLLFQHRLHADPRFAKAAIAGLIDRYPRRSYSIVHMGEQGAGGRRVWREGDFGGLDGARVLDAIERGRLWLNLRDGHAHDAELDATMRGLFAEAGALAPPVSSYGHRLGVLVSSPGAQVYYHADLPGQGLLQLHGRKRIYIYPPRLPFLSEQGLENIALSQLEVGLEYRPEFDREAMVFDLEPGQGLFWPLNSPHRIENHDSLNVSLTLEYWTQEIRRSQMINVANGILRNHYGVAPRSRKLGGPSFYAKAALQSLWRRSGRLDGLRRAARPIDFRLDPDRPGAILDLGAPKRRDGQGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGT9</accession>
    <name>A0A0S2DGT9_LYSEN</name>
    <protein>
        <submittedName>
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        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_11435</name>
        <name evidence="4" type="ORF">GLE_2270</name>
    </gene>
    <organism evidence="4 6">
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        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN57619">
        <property type="protein sequence ID" value="ALN57619"/>
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    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2270"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2235"/>
    <dbReference type="OMA" id="AGALNCW"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
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        <property type="entry name" value="Alpha_mannosidase"/>
    </dbReference>
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        <property type="entry name" value="GH-type_carb-bd"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
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        </location>
    </feature>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
            <begin position="300"/>
            <end position="801"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="825" mass="89886" checksum="2629B52B85C30C97" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH30</accession>
    <name>A0A0S2DH30_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_11165</name>
        <name evidence="2" type="ORF">GLE_2218</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947371.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57567">
        <property type="protein sequence ID" value="ALN57567"/>
        <property type="gene ID" value="GLE_2218"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2218"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2180"/>
    <dbReference type="OrthoDB" id="2095254at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="71" mass="8086" checksum="8633E1E3230B1033" modified="2016-02-17" version="1">MDLETIGEVVQIDDVQEVNQRLQDGWVVLAVAPGTKAGGEPWLRYSMGLPYEDEEDEDEEEEEGEEEDEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH57</accession>
    <name>A0A0S2DH57_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2616</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57964">
        <property type="protein sequence ID" value="ALN57964"/>
        <property type="gene ID" value="GLE_2616"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2616"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="38" mass="4129" checksum="1C5A3B3F7A8292C8" modified="2016-02-17" version="1">MTECTVRNWESGMHRMRSDSIDLSVAPTKTALFSAAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH83</accession>
    <name>A0A0S2DH83_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA polymerase sigma factor, sigma-70 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_2548</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2548"/>
    <dbReference type="EnsemblBacteria" id="ALN57897">
        <property type="protein sequence ID" value="ALN57897"/>
        <property type="gene ID" value="GLE_2548"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2548"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2508"/>
    <dbReference type="OMA" id="YLYRTAH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="4">
        <location>
            <begin position="36"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="5">
        <location>
            <begin position="129"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="188" mass="20722" checksum="72D1448E97DD91A2" modified="2016-02-17" version="1">MPSRAELAGARVMAGAGTRDCGEDERPPGLAELLIRERPALLRLVQRILGGDHAAEDVVQAVWLKLRNVGDASAIDNPRAYLFKLAANLATDWGRERTRRSQLLAEHYLWGPDEALSAEEQAMAQDELQRVLAAAGRLPEPTRTIFRLNRLQGLTQAEIARRLGVSVTTVENHVRAALQRLAHARAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH91</accession>
    <name>A0A0S2DH91_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">50S ribosomal protein L9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">rplI</name>
        <name evidence="10" type="ORF">FE772_13275</name>
        <name evidence="9" type="ORF">GLE_2648</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial ribosomal protein bL9 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947703.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2648"/>
    <dbReference type="EnsemblBacteria" id="ALN57996">
        <property type="protein sequence ID" value="ALN57996"/>
        <property type="gene ID" value="GLE_2648"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2648"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2607"/>
    <dbReference type="OMA" id="MKIILTH"/>
    <dbReference type="OrthoDB" id="1959318at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.430.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00503">
        <property type="entry name" value="Ribosomal_L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000244">
        <property type="entry name" value="Ribosomal_L9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_L9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020594">
        <property type="entry name" value="Ribosomal_L9_bac/chp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020069">
        <property type="entry name" value="Ribosomal_L9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036791">
        <property type="entry name" value="Ribosomal_L9_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020070">
        <property type="entry name" value="Ribosomal_L9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036935">
        <property type="entry name" value="Ribosomal_L9_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21368">
        <property type="entry name" value="PTHR21368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03948">
        <property type="entry name" value="Ribosomal_L9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01281">
        <property type="entry name" value="Ribosomal_L9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55653">
        <property type="entry name" value="SSF55653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="SSF55658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00158">
        <property type="entry name" value="L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00651">
        <property type="entry name" value="RIBOSOMAL_L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="RIBOSOMAL_L9" evidence="8">
        <location>
            <begin position="13"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN57996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW26490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="150" mass="15948" checksum="F07A8F0ADF544FD1" modified="2016-02-17" version="1">MQLILLQKVTNLGNLGDKVNVKPGYGRNYLVPQGKAVPATAANLAEFETRRAEYEANAKSLLEGAEGRKAKLEGVEVTITANAATEGKLYGSVTPRDIAEALTKAGFEVGKSEVIMGEGPIRRTGEYDVLIHLHADVETSVKVIVIGDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHN2</accession>
    <name>A0A0S2DHN2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type VI secretion system protein TssA</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Type VI secretion-associated protein, ImpA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tssA</name>
        <name evidence="3" type="ORF">FE772_13010</name>
        <name evidence="2" type="ORF">GLE_2591</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947661.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2591"/>
    <dbReference type="EnsemblBacteria" id="ALN57939">
        <property type="protein sequence ID" value="ALN57939"/>
        <property type="gene ID" value="GLE_2591"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2591"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2550"/>
    <dbReference type="OMA" id="KPEQQFG"/>
    <dbReference type="OrthoDB" id="761542at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010657">
        <property type="entry name" value="ImpA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017740">
        <property type="entry name" value="TssA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37951">
        <property type="entry name" value="PTHR37951"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06812">
        <property type="entry name" value="ImpA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03363">
        <property type="entry name" value="VI_chp_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ImpA_N" evidence="1">
        <location>
            <begin position="6"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="339" mass="36610" checksum="76A4D1E8BA488910" modified="2016-02-17" version="1">MSERLLQPLDGDEPCGPNLEYDPDFQTLEELAEPRPERTLGAGTIASEPIEWQRIADQADALLQRSKDLRVAVHWCAARLHLDGVAGWAQGVALMRALLEHHWDSVHPRLDPSENDDPTERINAVAGLADNERMLSYLRGARLFRGSHPAHFSLRELRIAQGTLKIEPADAAGLPGLSAMEACLRECPLQELSALDAALAGAVADLGAMADVFGERTSLSGPDFAGLLRELRELRAFVHPALLERDASAAVAEAASAGDGAAAAPAASGRQGIERPEDVRRAIDQICDYYARVEPSSPVPLLLRRAQRLVGLDFAGLMRDLAPDGISQLQVISGQNHDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHW0</accession>
    <name>A0A0S2DHW0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TldD/PmbA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_2670</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase U62 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947721.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2670"/>
    <dbReference type="EnsemblBacteria" id="ALN58018">
        <property type="protein sequence ID" value="ALN58018"/>
        <property type="gene ID" value="GLE_2670"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2670"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2629"/>
    <dbReference type="OMA" id="IRVGHAS"/>
    <dbReference type="OrthoDB" id="806701at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045569">
        <property type="entry name" value="Metalloprtase-TldD/E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002510">
        <property type="entry name" value="Metalloprtase-TldD/E_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035068">
        <property type="entry name" value="TldD/PmbA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036059">
        <property type="entry name" value="TldD/PmbA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01523">
        <property type="entry name" value="PmbA_TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19289">
        <property type="entry name" value="PmbA_TldD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111283">
        <property type="entry name" value="SSF111283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PmbA_TldD" evidence="2">
        <location>
            <begin position="58"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_C" evidence="3">
        <location>
            <begin position="287"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="542" mass="58218" checksum="272B5935632B7866" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHX4</accession>
    <name>A0A0S2DHX4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PepSY domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">PepSY-associated TM helix domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_12815</name>
        <name evidence="2" type="ORF">GLE_2554</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947632.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2554"/>
    <dbReference type="EnsemblBacteria" id="ALN57903">
        <property type="protein sequence ID" value="ALN57903"/>
        <property type="gene ID" value="GLE_2554"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2554"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2514"/>
    <dbReference type="OMA" id="WELAVFF"/>
    <dbReference type="OrthoDB" id="1656356at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005625">
        <property type="entry name" value="PepSY-ass_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34219">
        <property type="entry name" value="PTHR34219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03929">
        <property type="entry name" value="PepSY_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="349"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="382"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="421"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="453"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="482"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="526" mass="57010" checksum="BE0ECE3FCFBC190D" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHY2</accession>
    <name>A0A0S2DHY2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rluB</name>
        <name evidence="6" type="ORF">GLE_2792</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2792"/>
    <dbReference type="EnsemblBacteria" id="ALN58140">
        <property type="protein sequence ID" value="ALN58140"/>
        <property type="gene ID" value="GLE_2792"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2792"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2748"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00093">
        <property type="entry name" value="TIGR00093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="5">
        <location>
            <begin position="26"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="300"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="494"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="311"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="494"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="528"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="626"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="718"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="763"/>
            <end position="781"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="914" mass="100347" checksum="EEC9CB7488320695" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHY9</accession>
    <name>A0A0S2DHY9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Type IV pilus assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pilH</name>
        <name evidence="4" type="ORF">BV903_19845</name>
        <name evidence="5" type="ORF">FE772_13660</name>
        <name evidence="3" type="ORF">GLE_2730</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000058">
        <property type="protein sequence ID" value="OPD62187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947771.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000058.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2730"/>
    <dbReference type="EnsemblBacteria" id="ALN58078">
        <property type="protein sequence ID" value="ALN58078"/>
        <property type="gene ID" value="GLE_2730"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62187">
        <property type="protein sequence ID" value="OPD62187"/>
        <property type="gene ID" value="BV903_19845"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2730"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2688"/>
    <dbReference type="OMA" id="RDYITKP"/>
    <dbReference type="OrthoDB" id="1729688at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD62187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="123" mass="13445" checksum="AC07EA702430B173" modified="2016-02-17" version="1">MARILIVDDSPSQLMGIRRIVEKLGHEALTAEDGAAGVEAAKRELPDLILMDVVMPNLNGFQATRSICRESTTKHIPIVLVTTKDQDTDRVWGMRQGAKAYITKPFSETDLSEIIGQLLPSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI17</accession>
    <name>A0A0S2DI17_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LacI family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BV903_21350</name>
        <name evidence="5" type="ORF">GLE_2762</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000069">
        <property type="protein sequence ID" value="OPD61913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2762"/>
    <dbReference type="EnsemblBacteria" id="ALN58110">
        <property type="protein sequence ID" value="ALN58110"/>
        <property type="gene ID" value="GLE_2762"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61913">
        <property type="protein sequence ID" value="OPD61913"/>
        <property type="gene ID" value="BV903_21350"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2762"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2719"/>
    <dbReference type="OMA" id="KINEDFW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="17"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD61913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="337" mass="36320" checksum="D2AED841A66E7526" modified="2016-02-17" version="1">MSRPRAANPTRKAGEHLTMADLAELAGVSAITVSRALRDSPLVNPETRQRIKELAERQGYQFNISARNLRLRRSMTVAVVVEMKPTVERQMSGPYPLDLLGGISQELTSAGYSVLLTSLQGGALPSVQAADGVILLGQGAHEDAMHEVRRWGRPMVVWGAVSRHESQVVVGSDNQRGGKLAAERFLALGRRRPVFLGDDAHGEFAERLLGFREALRGHGIEPLTPTVANFTVSAGAQAVHALLDQHPQFDALFAASDLLAIGAIRALIERGRRVPEDVSVIGYDDTPLGATYLPPLTSIHQNFVDAGVLLARKVLALIEGEPAASEILPTHLVARVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ36</accession>
    <name>A0A0S2DJ36_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ferredoxin--NADP(+) reductase</fullName>
            <ecNumber evidence="4">1.18.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_3078</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + NADP(+) + 2 reduced [2Fe-2S]-[ferredoxin] = NADPH + 2 oxidized [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:20125"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.18.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ferredoxin--NADP reductase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="1.18.1.2" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3078"/>
    <dbReference type="EnsemblBacteria" id="ALN58425">
        <property type="protein sequence ID" value="ALN58425"/>
        <property type="gene ID" value="GLE_3078"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3078"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3037"/>
    <dbReference type="OMA" id="MTSEHYW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004324">
        <property type="term" value="F:ferredoxin-NADP+ reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06195">
        <property type="entry name" value="FNR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033892">
        <property type="entry name" value="FNR_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="260" mass="29594" checksum="531A24A5E3563BCB" modified="2016-02-17" version="1">MLDVRHWTDDYFSFTTTRDDGFRFDNGQFVMIGLQVPNENGVVKPLLRAYSIASANWEEQLEFFSIKVPNGPLTSRLKSIQPGDSVLVGRKPTGTLLIHDLHPGRNLYLLGTGTGFAPWLSVIKDPETYERFENVVLCHGVRSEQDLAYRDYIVNELPQHEFLGEQIAAKLKYYPAVTREDFVFDGRDQRGRLTQMMDSGRMTDQLGLAPLDAEHDRAMICGSPQMLADFREILDRRGFVAAPRIGTPGQYVFERAFVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ72</accession>
    <name>A0A0S2DJ72_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Apolipoprotein N-acyltransferase</fullName>
            <shortName evidence="9">ALP N-acyltransferase</shortName>
            <ecNumber evidence="9">2.3.1.269</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 11" type="primary">lnt</name>
        <name evidence="11" type="ORF">GLE_3228</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a glycerophospholipid + N-terminal S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein] = a 2-acyl-sn-glycero-3-phospholipid + H(+) + N-acyl-S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein]</text>
            <dbReference type="Rhea" id="RHEA:48228"/>
            <dbReference type="Rhea" id="RHEA-COMP:14681"/>
            <dbReference type="Rhea" id="RHEA-COMP:14684"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136912"/>
            <dbReference type="ChEBI" id="CHEBI:140656"/>
            <dbReference type="ChEBI" id="CHEBI:140657"/>
            <dbReference type="ChEBI" id="CHEBI:140660"/>
            <dbReference type="EC" id="2.3.1.269"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Protein modification; lipoprotein biosynthesis (N-acyl transfer).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.269" evidence="9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3228"/>
    <dbReference type="EnsemblBacteria" id="ALN58574">
        <property type="protein sequence ID" value="ALN58574"/>
        <property type="gene ID" value="GLE_3228"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3228"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3181"/>
    <dbReference type="OMA" id="INDHGAD"/>
    <dbReference type="UniPathway" id="UPA00666"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016410">
        <property type="term" value="F:N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042158">
        <property type="term" value="P:lipoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07571">
        <property type="entry name" value="ALP_N-acyl_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01148">
        <property type="entry name" value="Lnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004563">
        <property type="entry name" value="Apolipo_AcylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045378">
        <property type="entry name" value="LNT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20154">
        <property type="entry name" value="LNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00546">
        <property type="entry name" value="lnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="483"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="533"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="565"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="691"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="776"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="domain" description="CN hydrolase" evidence="10">
        <location>
            <begin position="208"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN58574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="798" mass="84841" checksum="5722F7DA5FC2B874" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ84</accession>
    <name>A0A0S2DJ84_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_16130</name>
        <name evidence="2" type="ORF">GLE_3256</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3256"/>
    <dbReference type="EnsemblBacteria" id="ALN58602">
        <property type="protein sequence ID" value="ALN58602"/>
        <property type="gene ID" value="GLE_3256"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3256"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3210"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242675" evidence="1">
        <location>
            <begin position="27"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="300" mass="31621" checksum="685747F0F4DA146A" modified="2016-02-17" version="1">MTRLSTMCGALALAIAGLAAAPSALAETSYSFASETGDYIGQGQSKTYTGADSTIAVSGNAQALQMSVNRGNDNWRIELSAPRGQRLQPGRYYFAERSAFRTGRSPGIDIGGNGRGCGSTWGSVYIQQIEFGANDAVTALEATGLQRCELENAPLLTAKLRYNVQPLSLALDSDAGDYIGRGLRKDYAGDTSTFAVSGNAGYLIYNVSGQRDSWSAILRPPTGQTLGVGTYPISRFGDANSVGFDFAGNGRGCNRVAGSIAIKAVEVDPVSRMVTGLSADFEQRCEAGSTALRGSIRYKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJE6</accession>
    <name>A0A0S2DJE6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_15850</name>
        <name evidence="1" type="ORF">GLE_3191</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948111.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3191"/>
    <dbReference type="EnsemblBacteria" id="ALN58537">
        <property type="protein sequence ID" value="ALN58537"/>
        <property type="gene ID" value="GLE_3191"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3191"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3145"/>
    <dbReference type="OMA" id="TSDYVWR"/>
    <dbReference type="OrthoDB" id="1970612at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010239">
        <property type="entry name" value="CHP02001"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09694">
        <property type="entry name" value="Gcw_chp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02001">
        <property type="entry name" value="gcw_chp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="248" mass="26904" checksum="E4A2141CD815D577" modified="2016-02-17" version="1">MSSSHHLFRRREAAAPLLLAACAGLGLLTLGADARAEQAPAFTLSGSAALTSDYVWRGSSQTQGDPTAQVGVKAAHRSGFYAQVWGSGVEFAPDTHASSELDFTVGWAGKLAPDWALDVNVLHYRYPSTTVDLNWTELNGTVTYRDAYWLSLAYSNEALGSKDRGIYSQVGARFPVSDALRFEAAVGHYFLDDVYGRSYSHGQLSAIWAFRSPFELRLTAHGTDRNAERIFGDSLAGSRIEAALQASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJE7</accession>
    <name>A0A0S2DJE7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">4-hydroxy-tetrahydrodipicolinate synthase</fullName>
            <shortName evidence="9">HTPA synthase</shortName>
            <ecNumber evidence="4 9">4.3.3.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 11" type="primary">dapA</name>
        <name evidence="12" type="ORF">BV903_09360</name>
        <name evidence="13" type="ORF">FE772_15815</name>
        <name evidence="11" type="ORF">GLE_3183</name>
    </gene>
    <organism evidence="11 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">C3</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">B25</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>L-aspartate 4-semialdehyde + pyruvate = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:34171"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="4.3.3.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the DapA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.7" evidence="4 9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000020">
        <property type="protein sequence ID" value="OPD64241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948105.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000020.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3183"/>
    <dbReference type="EnsemblBacteria" id="ALN58529">
        <property type="protein sequence ID" value="ALN58529"/>
        <property type="gene ID" value="GLE_3183"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64241">
        <property type="protein sequence ID" value="OPD64241"/>
        <property type="gene ID" value="BV903_09360"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3183"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3138"/>
    <dbReference type="OMA" id="ALCAMIT"/>
    <dbReference type="OrthoDB" id="1438588at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00017"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00950">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00418">
        <property type="entry name" value="DapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005263">
        <property type="entry name" value="DapA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020625">
        <property type="entry name" value="Schiff_base-form_aldolases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020624">
        <property type="entry name" value="Schiff_base-form_aldolases_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="PTHR12128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00674">
        <property type="entry name" value="dapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00665">
        <property type="entry name" value="DHDPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00666">
        <property type="entry name" value="DHDPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="9 10 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 9" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="site" description="Part of a proton relay during catalysis" evidence="9">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <feature type="site" description="Part of a proton relay during catalysis" evidence="9">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN58529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OPD64241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW26889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="301" mass="31109" checksum="2B57DF8BEB16713A" modified="2016-02-17" version="1">MRLTGSITALATPFTASAELDLDAWRTLLAKQLEGGTQAVVVAGSTGEAAALFDAEYDTLLRSAVEFVAGRIPVLAGTGLSNTAKTIELNRRVAALGADAALVVAPPYVRPTQAGLLAHYRAIADDGALPVVLYNVPGRTGCDLLPATVAELAAHPRIVGIKEAVSDPQRMHELLALKSDAFAVLSGDDPTACRAMLAGADGIVSVGSNAMPAAFRRLADLARAGKRGDAEAWDARLRPAYDFLGVEPNPIPVKALLAAQGIGHGLRLPLQTLSPAHADAARQASALAAELEHLSRANLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJP9</accession>
    <name>A0A0S2DJP9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF541 domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_16820</name>
        <name evidence="2" type="ORF">GLE_3409</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3409"/>
    <dbReference type="EnsemblBacteria" id="ALN58755">
        <property type="protein sequence ID" value="ALN58755"/>
        <property type="gene ID" value="GLE_3409"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3409"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3359"/>
    <dbReference type="OMA" id="LPNGPHI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007497">
        <property type="entry name" value="DUF541"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04402">
        <property type="entry name" value="SIMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726571" evidence="1">
        <location>
            <begin position="49"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="269" mass="28315" checksum="8219A1D52393707D" modified="2016-02-17" version="1">MTRSSSSPLVRLPSLPSLSSRLSRLSLRPLALAAVLAFGAATAMTASAQTAPYVATDGTLLSVSAESTAKRTPNIATVSTGVVTQAADANAAMRANAEQMAKVVAAIKAAGIAERDIQTSGINLNPQYRYQENQPPQITGYQANNNVNIVIRDISKVGKILDSLVATGANQINGPTFDLDDKDKDAAFDEARRGAIEKAQARAEMYAKTLGMKVRRIVSVSEGGRFAPPMPMPMMAMRMEKAGAAADTSVSPGENSLSMNLDVVFELGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJX9</accession>
    <name>A0A0S2DJX9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Peptidase, family M13</fullName>
            <ecNumber evidence="11">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLE_3487</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M13 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="11"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58832">
        <property type="protein sequence ID" value="ALN58832"/>
        <property type="gene ID" value="GLE_3487"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3487"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3432"/>
    <dbReference type="OMA" id="GYPDEIM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08662">
        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="PTHR11733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00786">
        <property type="entry name" value="NEPRILYSIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595136" evidence="8">
        <location>
            <begin position="21"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M13_N" evidence="10">
        <location>
            <begin position="74"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M13" evidence="9">
        <location>
            <begin position="502"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN58832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="706" mass="77100" checksum="DE819A7AE25CF1B2" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
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        </recommendedName>
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    <gene>
        <name evidence="10" type="primary">pkn2</name>
        <name evidence="10" type="ORF">GLE_3548</name>
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        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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            <taxon>Proteobacteria</taxon>
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    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3548"/>
    <dbReference type="EnsemblBacteria" id="ALN58892">
        <property type="protein sequence ID" value="ALN58892"/>
        <property type="gene ID" value="GLE_3548"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3548"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3492"/>
    <dbReference type="OMA" id="CLLTANW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
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        <property type="entry name" value="Prot_kinase_dom"/>
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    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
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        <property type="match status" value="9"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="10" id="KW-0418">Kinase</keyword>
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    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="25"/>
            <end position="286"/>
        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        <location>
            <position position="54"/>
        </location>
        <ligand>
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        </ligand>
    </feature>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN58892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1146" mass="120264" checksum="2CA5BA0547D801A0" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK48</accession>
    <name>A0A0S2DK48_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3566</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="ALN58910"/>
        <property type="gene ID" value="GLE_3566"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3566"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3510"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595144" evidence="2">
        <location>
            <begin position="30"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="142" mass="15036" checksum="B59478D1F28E89F1" modified="2016-02-17" version="1">MKGISSYGRSGVCALALLGGMAGSTVAAARDKAAEETENLQRFAEVMLAKGRNEQCKVLDEARTQQLDDDVTAILKKLEKRVSPQKLLGVALNATVATGEPASAANCDEAARQSVEAGSEQARTWADELRGRRSRGNSTQGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK70</accession>
    <name>A0A0S2DK70_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3555</name>
    </gene>
    <organism evidence="2 3">
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        <lineage>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3555"/>
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        <location>
            <begin position="362"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="385" mass="39739" checksum="50AE69ADB0783761" modified="2016-02-17" version="1">MANTRLGSRWSLVPEQQADFVVVDMDSMYGPMSWLRLHAAGKSVIALTAAQRTQADFLLGHPFSADSIAELLGEIAGQNGEPAAAAAAPKPVEIPQQPRTDPTAALPDVVVELLQTDLAQAKAATPAVAAPAAPASIAAAPVEPVAAVAPTAAVAPPAPAAAVAPTTPAAPAPATPAPGLVAPAAPAPASVPATAASVTARGDGLLDWLVPGRLRGLLRVGSGEERLLIDADQRRYHGPAALKPLSALFERGFAASEFELLPAAQWDAAAAQLGAPMPLARLVWFGNLLAGRGRLAPGYDPARRYRMTKWPQTEREYPKHFRIATVMMKGLSHLAEIAEASGVSEAEVADFINANLATGFAEAEGDPPPAEQAKSGGLFGRLRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK79</accession>
    <name>A0A0S2DK79_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_20530</name>
        <name evidence="2" type="ORF">GLE_3341</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="BV903_20530"/>
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    <evidence type="ECO:0000256" key="1">
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        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="OPD62070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="461" mass="47853" checksum="429F5900DDC985F6" modified="2016-02-17" version="1">MIRKNALCLALVAGLSGFCTLASAKSPVAEMDSAPVTGTPSAGAMGAAEFAATAKASVPRVVSLGQPTSLDVSALKSRRFEQDKHGQPLEIGFARDIARSAVDLNTLAWQPLADGGRAARFEVSSAGAVALRAGLSLRGAGAKSATLHFAGSDGRVFAQSGADFAGNELGWSPVVAGDTLTVELVLPKGVNAKALKLNLPQLSHLDISPVASDRQIQEKVAKVGESDYCEKDIVCRVSPPSGFVSTAKSVARMTFTTSGGTYLCTGTLLNNNHSPKKRLFWTAAHCISTQTVANTLQTYWFYDVTTCGGSTVNPAYTTLSGGAYLRHANTTRDTALLELKTAPPSGAVYAGWSSAAIAATGTAIEGIHHPAGDVKKYSLGSVNGLSTSIDGKSPLYRVVWSTGVTEGGSSGSGLFTVTSSGGYQLRGGLYGGTSYCSAPRDPDYYSRFADIYSSVSSYFNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK86</accession>
    <name>A0A0S2DK86_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_24275</name>
        <name evidence="4" type="ORF">FE772_17815</name>
        <name evidence="2" type="ORF">GLE_3620</name>
    </gene>
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        <name type="scientific">Lysobacter enzymogenes</name>
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        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD61320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948422.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000092.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3620"/>
    <dbReference type="EnsemblBacteria" id="ALN58964">
        <property type="protein sequence ID" value="ALN58964"/>
        <property type="gene ID" value="GLE_3620"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61320">
        <property type="protein sequence ID" value="OPD61320"/>
        <property type="gene ID" value="BV903_24275"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3620"/>
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    <dbReference type="OrthoDB" id="1447353at2"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595150" evidence="1">
        <location>
            <begin position="26"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="168" mass="18308" checksum="B91C30729F35CBD9" modified="2016-02-17" version="1">MRIGNQWWAVLLLLGVFGQSNQALAAQSKPQADTASYTELGGYLHSDAEINAWYELLYRLRENFDEICGDTFCEGDYSNIQALRFVCSVETGSGVLGQCVWTFAASHEEVDAATGRVAVAPKVWRCRAPLARKTTAQALLGALAGERPLYAPLPGTTKSIYDGLIDCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKV1</accession>
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        <submittedName>
            <fullName evidence="5">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_3933</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN59275">
        <property type="protein sequence ID" value="ALN59275"/>
        <property type="gene ID" value="GLE_3933"/>
    </dbReference>
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    <dbReference type="PATRIC" id="fig|69.6.peg.3870"/>
    <dbReference type="OMA" id="MEVYFTT"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="79"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="127"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="529" mass="54997" checksum="8A179C2F35894110" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL11</accession>
    <name>A0A0S2DL11_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">50S ribosomal protein L11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 12" type="primary">rplK</name>
        <name evidence="14" type="ORF">BV903_21095</name>
        <name evidence="15" type="ORF">FE772_18705</name>
        <name evidence="12" type="ORF">GLE_3801</name>
        <name evidence="13" type="ORF">LEN_1342</name>
        <name evidence="16" type="ORF">SAMN05421681_11810</name>
    </gene>
    <organism evidence="12 17">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 17">C3</strain>
        </source>
    </reference>
    <reference evidence="20" key="2">
        <citation type="journal article" date="2016" name="DNA Res." volume="0" first="0" last="0">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer, Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">M497-1</strain>
        </source>
    </reference>
    <reference evidence="16 18" key="3">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">ATCC 29487</strain>
        </source>
    </reference>
    <reference evidence="13 20" key="4">
        <citation type="journal article" date="2017" name="DNA Res." volume="24" first="169" last="177">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
            <dbReference type="PubMed" id="28065880"/>
            <dbReference type="DOI" id=".1093/dnares/dsw055"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 20">M497-1</strain>
        </source>
    </reference>
    <reference evidence="14 19" key="5">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 19">B25</strain>
        </source>
    </reference>
    <reference evidence="15 21" key="6">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 21">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 9">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="PTM">
        <text evidence="7 9">One or more lysine residues are methylated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP014940">
        <property type="protein sequence ID" value="BAV96829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000067">
        <property type="protein sequence ID" value="OPD61938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNOG01000018">
        <property type="protein sequence ID" value="SDY30301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948565.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000067.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3801"/>
    <dbReference type="EnsemblBacteria" id="ALN59145">
        <property type="protein sequence ID" value="ALN59145"/>
        <property type="gene ID" value="GLE_3801"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAV96829">
        <property type="protein sequence ID" value="BAV96829"/>
        <property type="gene ID" value="LEN_1342"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61938">
        <property type="protein sequence ID" value="OPD61938"/>
        <property type="gene ID" value="BV903_21095"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY30301">
        <property type="protein sequence ID" value="SDY30301"/>
        <property type="gene ID" value="SAMN05421681_11810"/>
    </dbReference>
    <dbReference type="KEGG" id="lem:LEN_1342"/>
    <dbReference type="KEGG" id="lez:GLE_3801"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3745"/>
    <dbReference type="OMA" id="CKQFNAK"/>
    <dbReference type="OrthoDB" id="1702697at2"/>
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        <location>
            <begin position="9"/>
            <end position="67"/>
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        <location>
            <begin position="72"/>
            <end position="140"/>
        </location>
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    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAV96829.1"/>
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            <dbReference type="EMBL" id="OPD61938.1"/>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000183696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
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        <source>
            <dbReference type="Proteomes" id="UP000218824"/>
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    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="142" mass="14726" checksum="45328B3350347C04" modified="2016-02-17" version="1">MAKKVVGYIKLQVKAGQANPSPPVGPALGQRGLNIMEFCKAFNAATSKLEPGLPTPVIITAYSDRTFTFVTKSTPASVLLKKAAGITSGSKRPNTDKVGKVTRAQLEAIAKQKEADLTAADLDAAVKTIAGSARSMGLVVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL18</accession>
    <name>A0A0S2DL18_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">MbtH family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_07445</name>
        <name evidence="4" type="ORF">FE772_18115</name>
        <name evidence="2" type="ORF">GLE_3677</name>
    </gene>
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        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
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            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_3677"/>
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        <property type="gene ID" value="GLE_3677"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD64591"/>
        <property type="gene ID" value="BV903_07445"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3677"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3619"/>
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    <dbReference type="OrthoDB" id="2067093at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005153">
        <property type="entry name" value="MbtH-like_dom"/>
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        <property type="entry name" value="MbtH-like_sf"/>
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        <property type="entry name" value="MLP_fam"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="3"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="72" mass="8182" checksum="85EC4B5530A56F2B" modified="2016-02-17" version="1">MTNPFEDNNGTFLVLVNDENQHSLWPEFAEVPAGWRTVFGPEQRQACLDYVEQNWTDMRPASLAALDDARVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL50</accession>
    <name>A0A0S2DL50_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">AgaS</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">SIS domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FE772_17975</name>
        <name evidence="6" type="ORF">GLE_3656</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>D-galactosamine 6-phosphate + H2O = D-tagatopyranose 1-phosphate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:47680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:71674"/>
            <dbReference type="ChEBI" id="CHEBI:138150"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIS family. AgaS subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948447.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3656"/>
    <dbReference type="EnsemblBacteria" id="ALN59000">
        <property type="protein sequence ID" value="ALN59000"/>
        <property type="gene ID" value="GLE_3656"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3656"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3600"/>
    <dbReference type="OMA" id="YHLIITC"/>
    <dbReference type="OrthoDB" id="1046291at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05010">
        <property type="entry name" value="SIS_AgaS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035464">
        <property type="entry name" value="SIS_AgaS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="SIS" evidence="5">
        <location>
            <begin position="49"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="5">
        <location>
            <begin position="220"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW27238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="389" mass="41840" checksum="9DC7745605614EA1" modified="2016-02-17" version="1">MDVTPLSDSSAWQRLGGADTAAEIAQQPALWEQLAADLAQARERVQAFLGDRLDDPRQRVLFTGAGSSGFIADMVADRINAQWPADVRAVHTTSLLTHPALYLQRDRPTLLVSFGRSGSSPESVAAVDLLRAQVDDARFLDITCNADGELARRGQGREDTCTLLMPAASCDRAFAMTSSLSCMLLAALCVFDAAPWQQRLERLDQVAALAREGLAQWSQAAGALAQRPFQRVIYLASGPLEALAREAALKVLELTAGQVLALANTPLGFRHGPKSTLDGATLVVMMRSNHALARRYEQDLLDELRRDGVAGQVLAIGPHSDIGGGDDYSLRVPPLADSTLADSWLAPVWLTFAQVFALQRSAALDLTPDNPFPDGTVNRVVKGVTIHQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL77</accession>
    <name>A0A0S2DL77_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphate-selective porin O and P</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Porin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_18425</name>
        <name evidence="2" type="ORF">GLE_3741</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948514.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3741"/>
    <dbReference type="EnsemblBacteria" id="ALN59085">
        <property type="protein sequence ID" value="ALN59085"/>
        <property type="gene ID" value="GLE_3741"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3741"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3686"/>
    <dbReference type="OMA" id="NKYMIWR"/>
    <dbReference type="OrthoDB" id="1578713at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010870">
        <property type="entry name" value="Porin_O/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07396">
        <property type="entry name" value="Porin_O_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726734" evidence="1">
        <location>
            <begin position="27"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="400" mass="43709" checksum="8D88D74D5A271162" modified="2016-02-17" version="1">MRNARFAFAASPIALALCALPQAAPAASFDDWPTKHRFGDGSEISATANWAYDVVDFDGDGYGTAATRLKDDGHYRRREFGVNLKKKDVYDFTAVFDFESKLWLDVAVRLETKAAFGADYGKVRIGYFKTPVSMESVAASRAGSLLELSAASQAIYEGRRTGVEWSLERPRYALGAGYFFGHDLQGDNPGTTAAGRAVWTPVKDADHVVHLGLTGSVENPHGYRDGRGAYFGPAARLRARPLNGLTATRLVDSGSLRDTDKIVRNGLEALWIDGPWSLQAEYLRATAQRDNGQRDFSADGYYLTGSWVLTGETRPYAGNNVGNVKPAHGYGAVELLARYGELDLDDGGIAGGKQRDWTLGANWYLTSHFKFQANYVHVEADKGLLSADPDAVELRAQVQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL80</accession>
    <name>A0A0S2DL80_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phenazine biosynthesis protein PhzF family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3991</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhzF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948696.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3991"/>
    <dbReference type="EnsemblBacteria" id="ALN59333">
        <property type="protein sequence ID" value="ALN59333"/>
        <property type="gene ID" value="GLE_3991"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3991"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3928"/>
    <dbReference type="OMA" id="PGYEMRF"/>
    <dbReference type="OrthoDB" id="1468060at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003719">
        <property type="entry name" value="Phenazine_PhzF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774">
        <property type="entry name" value="PTHR13774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02567">
        <property type="entry name" value="PhzC-PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016184">
        <property type="entry name" value="PhzC_PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00654">
        <property type="entry name" value="PhzF_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR016184-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="296" mass="31233" checksum="2A873AAA4000D819" modified="2016-02-17" version="1">MSLRRYLQLDVFAHRIGAGNPLAVVFDAQGLDDAAMQSFAAWMHLPETVFLLPPGPGADYRARIFTPTRELDFAGHPSVGAAWAVLDAGRVAPHRDALVQECAAGQLPVRIVHDATGPRVSVRTPRARRIERAGEDDAARLAAALRGLALADRATGALAPALWDNGVRWWLAEAGDARALREWRPDPAVLAAIAELGGDALGLAVFAAGDVPGCARTVRAFCPGDGFAEDPVTGSANAAIASALLEAGRLRAGEGYCASQGREVGRDGRVELRVDEDAAVWVGGRVQAVIRGSVEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLB2</accession>
    <name>A0A0S2DLB2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">30S ribosomal protein S5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">rpsE</name>
        <name evidence="13" type="ORF">BV903_22950</name>
        <name evidence="15" type="ORF">D9T17_09515</name>
        <name evidence="14" type="ORF">FE772_18565</name>
        <name evidence="12" type="ORF">GLE_3773</name>
    </gene>
    <organism evidence="12 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 16">C3</strain>
        </source>
    </reference>
    <reference evidence="13 17" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 17">B25</strain>
        </source>
    </reference>
    <reference evidence="15 18" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 18">OH11</strain>
        </source>
    </reference>
    <reference evidence="14 19" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 19">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.</text>
    </comment>
    <comment type="function">
        <text evidence="8">With S4 and S12 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 10">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000077">
        <property type="protein sequence ID" value="OPD61600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000023">
        <property type="protein sequence ID" value="ROU07198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948540.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3773"/>
    <dbReference type="EnsemblBacteria" id="ALN59117">
        <property type="protein sequence ID" value="ALN59117"/>
        <property type="gene ID" value="GLE_3773"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61600">
        <property type="protein sequence ID" value="OPD61600"/>
        <property type="gene ID" value="BV903_22950"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3773"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3717"/>
    <dbReference type="OMA" id="KRGCGSW"/>
    <dbReference type="OrthoDB" id="1505038at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01307_B">
        <property type="entry name" value="Ribosomal_S5_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_S5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005712">
        <property type="entry name" value="Ribosomal_S5_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_S5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_S5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018192">
        <property type="entry name" value="Ribosomal_S5_N_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718">
        <property type="entry name" value="PTHR13718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01021">
        <property type="entry name" value="rpsE_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00585">
        <property type="entry name" value="RIBOSOMAL_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 8 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="S5 DRBM" evidence="11">
        <location>
            <begin position="23"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN59117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OPD61600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW28814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROU07198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="179" mass="19064" checksum="EE7D78230282B4F6" modified="2016-02-17" version="1">MADDRAPRGRDRDRNREEIDDGMIEKLIAVNRVSKTVKGGRQFTFTALTVVGDGNGKVGFGYGKAREVPVAIQKSMEYARKAMNTVELNNGTLWHAVKSGHGAAHVFMQPASEGTGVIAGGAMRAVLEAVGVKNVLAKATGSRNPINLVRATVKGLTDMHSPAKIAAKRGKKVEDLLNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLC7</accession>
    <name>A0A0S2DLC7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3973</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59315">
        <property type="protein sequence ID" value="ALN59315"/>
        <property type="gene ID" value="GLE_3973"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3973"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="97" mass="10781" checksum="8A3AD61CEE1BA6FB" modified="2016-02-17" version="1">MGSGFRRNDGRRVAYPTVGAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAPLLQGACRGTIRLYVCVRLTTSETSRASVRKRPGHFLCLKPQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLF1</accession>
    <name>A0A0S2DLF1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">General secretion pathway protein GspN</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">General secretion pathway protein N</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_07800</name>
        <name evidence="4" type="ORF">FE772_20470</name>
        <name evidence="2" type="ORF">GLE_4173</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000015">
        <property type="protein sequence ID" value="OPD64555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948848.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4173"/>
    <dbReference type="EnsemblBacteria" id="ALN59515">
        <property type="protein sequence ID" value="ALN59515"/>
        <property type="gene ID" value="GLE_4173"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64555">
        <property type="protein sequence ID" value="OPD64555"/>
        <property type="gene ID" value="BV903_07800"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4173"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4115"/>
    <dbReference type="OMA" id="YSEIAAH"/>
    <dbReference type="OrthoDB" id="1488781at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="258" mass="28036" checksum="7636C75D8B31DEAE" modified="2016-02-17" version="1">MRFDDASPRTWLLATAAGWALLTWVLALAGMGRHVDPLPPDPSLVKPLPQARKSPPDTLGPLTQYGEIAARPLFVDDRRPKPFFMQGKGEGENQQAAFDYLLTSVLITPQLSMAILQPADGSESVPVKLGEVPESHPAWRLTSLEPRRAVFEGPEGRRELDLRVYNGQGGQPPTAIAAPPTAGRPVPQPQPAPPNRPPPANAAPVQQPQPQPQPQPAEASAPLTEQAQMEAIRKRIEARRQQLRQQQQQAAQPPANSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLH1</accession>
    <name>A0A0S2DLH1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CopG family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_20145</name>
        <name evidence="2" type="ORF">GLE_4108</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948790.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59450">
        <property type="protein sequence ID" value="ALN59450"/>
        <property type="gene ID" value="GLE_4108"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4108"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4050"/>
    <dbReference type="OMA" id="AFHAEAQ"/>
    <dbReference type="OrthoDB" id="2029164at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="96" mass="10731" checksum="F3DAB6B74529110D" modified="2016-02-17" version="1">MSTTTIRLSDELKSRIADAAERAGTTPHGFILGALEEKVGEAERRAQFLDEAQERWRSFVADGQALEWGDMRDYLGRRARGENASPPAKKPFGRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLJ3</accession>
    <name>A0A0S2DLJ3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tol-Pal system protein TolB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">tolB</name>
        <name evidence="10" type="ORF">BV903_01145</name>
        <name evidence="11" type="ORF">FE772_19895</name>
        <name evidence="9" type="ORF">GLE_4052</name>
    </gene>
    <organism evidence="9 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">C3</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TolB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000002">
        <property type="protein sequence ID" value="OPD65886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948744.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4052"/>
    <dbReference type="EnsemblBacteria" id="ALN59394">
        <property type="protein sequence ID" value="ALN59394"/>
        <property type="gene ID" value="GLE_4052"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65886">
        <property type="protein sequence ID" value="OPD65886"/>
        <property type="gene ID" value="BV903_01145"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4052"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3995"/>
    <dbReference type="OMA" id="VREPSWG"/>
    <dbReference type="OrthoDB" id="821953at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017038">
        <property type="term" value="P:protein import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00671">
        <property type="entry name" value="TolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014167">
        <property type="entry name" value="Tol-Pal_TolB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007195">
        <property type="entry name" value="TolB_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04052">
        <property type="entry name" value="TolB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02800">
        <property type="entry name" value="propeller_TolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="5 7" id="KW-0574">Periplasm</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008995358" description="Tol-Pal system protein TolB" evidence="7">
        <location>
            <begin position="23"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="TolB_N" evidence="8">
        <location>
            <begin position="27"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN59394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD65886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW27566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="439" mass="46873" checksum="FEB83315B2133F0F" modified="2016-02-17" version="1" precursor="true">MKRPLRWLATLLAVLLPLAASAQQKGLEIDIVGGLASATPIAVVPMPYQGGGAAPPTDIAEVVRNDLNRSGQFRGLPVEQMAAKPTRGSEISFPDWRALNQDFIVVGRVLDAGAGSYRVEYELYDVGKQQRLLGFALTARANAMRDVAHQVADAVYEKITGVRGAFFTRIAYVTATGVGRGSNYALMVADSDGYNPQTVVRSPEPLLSPSWSPDGNRLAYVSFEGGNSSIYIQNIGTGSRELVAKFRGINGAPAFSPDGRRLALTLSRSGNPEIYVMDLGSKALTQLTNHFGIDTEPTWSADGNKIYFTSDRGGKPQIYSVATSGGSATRVTFQGSYNASASVSFDGKKIATAQGAGNTYRIAMMDSSTGGALWSTLSPGSLDESPSFAPNASMIIYAAREGRRGVLYAVSADARVRQRLVLADGDVREPAWGPYRLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLS1</accession>
    <name>A0A0S2DLS1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SMI1/KNR4 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_19930</name>
        <name evidence="2" type="ORF">GLE_4059</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948751.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59401">
        <property type="protein sequence ID" value="ALN59401"/>
        <property type="gene ID" value="GLE_4059"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4059"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4002"/>
    <dbReference type="OMA" id="DTFWDEA"/>
    <dbReference type="OrthoDB" id="619646at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1580.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018958">
        <property type="entry name" value="Knr4/Smi1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037883">
        <property type="entry name" value="Knr4/Smi1-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09346">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00860">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160631">
        <property type="entry name" value="SSF160631"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMI1_KNR4" evidence="1">
        <location>
            <begin position="31"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="SMI1_KNR4" evidence="1">
        <location>
            <begin position="213"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="366" mass="41510" checksum="3D5B611104B4349B" modified="2016-02-17" version="1">MAGNVLDWRVYGRAPSLDTFWDEAGNLGRAAASADDIAAVQARLRIELPPWLRALYARYDGGAVRMARAAALHSEDWIDADWLVPRARLLPLAEWFSLAELRRREDYRDDAFAALAADDSRLIAIALGEDNGTLCLDYSAGGEPRIVLTDQRQRLREYPDHTAFLADLVEIQYWNPALQARHDPRQRLRCDPRPPSLDTFWSGPGYWADAAAPADEAALAAAEARLGLRLPALLRALYLRQDGGSTEFVWAPLRRQPSWHLYDWESVVPGDSVAALADLRTLADWAADFQGSDALYGFVRNYAGCERLLILASHNIEWLLCLDYRERGPQQEPEVVYFEYFGELVANYRARDFHRFFADLRRGELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLZ0</accession>
    <name>A0A0S2DLZ0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59552">
        <property type="protein sequence ID" value="ALN59552"/>
        <property type="gene ID" value="GLE_4211"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4211"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4153"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="106" mass="11386" checksum="119A0AD300A54F88" modified="2016-02-17" version="1">MHASPLRTSVAQRIPPRLDAAARPRSADEAIRSDCVCCAAREGLSPKGSSAAIGRGGIFRRYRCKDTFSRTRCLVRSGFDVLSVVSLMNSESFARVSLSIGAPCLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLZ9</accession>
    <name>A0A0S2DLZ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arsenical resistance protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Arsenical resistance protein ArsH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">arsH</name>
        <name evidence="3" type="ORF">FE772_19695</name>
        <name evidence="2" type="ORF">GLE_4015</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948717.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4015"/>
    <dbReference type="EnsemblBacteria" id="ALN59357">
        <property type="protein sequence ID" value="ALN59357"/>
        <property type="gene ID" value="GLE_4015"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4015"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3952"/>
    <dbReference type="OMA" id="WSSPEMH"/>
    <dbReference type="OrthoDB" id="1818437at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014063">
        <property type="entry name" value="Arsenate-R_ArsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43590">
        <property type="entry name" value="PTHR43590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02690">
        <property type="entry name" value="resist_ArsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_red" evidence="1">
        <location>
            <begin position="35"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="240" mass="27145" checksum="875C7F8AC9266583" modified="2016-02-17" version="1">MSEARIDLPNIDATLFPQPDLERLFSLVRAIHAPRFLLLYGSLRERSYSRLVAEEAARILRALGGETRMFNPSGLPLVDDAPSDHPKVRELHELVQWAEGIVWSSPERHGAMTGLMKTQIDWIPLSVGAVRPTQGKTLAVMQVCGGSQSFNAVNQMRLLGRWMRMLTIPNQSSVAKAYQEFDDAGRMKPSPYYDRIVDVMEELVKFTLLTRESAPYLVDRYSERKESAEALARRMQQGAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM18</accession>
    <name>A0A0S2DM18_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Orotidine 5'-phosphate decarboxylase</fullName>
            <ecNumber evidence="7">4.1.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">OMP decarboxylase</fullName>
            <shortName evidence="7">OMPDCase</shortName>
            <shortName evidence="7">OMPdecase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">pyrF</name>
        <name evidence="10" type="ORF">FE772_20430</name>
        <name evidence="9" type="ORF">GLE_4166</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>H(+) + orotidine 5'-phosphate = CO2 + UMP</text>
            <dbReference type="Rhea" id="RHEA:11596"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="EC" id="4.1.1.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the OMP decarboxylase family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.23" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948842.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4166"/>
    <dbReference type="EnsemblBacteria" id="ALN59508">
        <property type="protein sequence ID" value="ALN59508"/>
        <property type="gene ID" value="GLE_4166"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4166"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4108"/>
    <dbReference type="OMA" id="QSAFFER"/>
    <dbReference type="OrthoDB" id="1181405at2"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
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        <property type="entry name" value="Aldolase_TIM"/>
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    </dbReference>
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        <property type="entry name" value="OMPdecase_type-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001754">
        <property type="entry name" value="OMPdeCOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00215">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00934">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="pyrF_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00156">
        <property type="entry name" value="OMPDECASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="6 7 9" id="KW-0456">Lyase</keyword>
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    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OMPdecase" evidence="8">
        <location>
            <begin position="17"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004861"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00008847"/>
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    </evidence>
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    </evidence>
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            <dbReference type="SMART" id="SM00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN59508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="270" mass="29066" checksum="F73FA52C1A1D3F6C" modified="2016-02-17" version="1">MSFMQALRRRWQQADTLVCVGLDPEPAKFPAAFAADADAVFAFNRDIVDATAQYACAFKPQIAHFAALRAEDALTRLIAHIHANHPDVPVILDSKRGDIGSTAQHYVGEAFERYRADAVTVNPYLGRDSVQPFLDRADRGVVILCRTSNPGAGDLQDLDVGGRPLYQLVAEKVARDWNEHGNCALVVGATWPEQLREVRAIVGDVPFLVPGVGAQGGDAGAVVSNAKSADGTGLMISSSRAILYASNGTDYAEAAANAARELRDEINRHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMF8</accession>
    <name>A0A0S2DMF8_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_11675</name>
        <name evidence="4" type="ORF">FE772_21295</name>
        <name evidence="2" type="ORF">GLE_4357</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW27801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59698">
        <property type="protein sequence ID" value="ALN59698"/>
        <property type="gene ID" value="GLE_4357"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD63707"/>
        <property type="gene ID" value="BV903_11675"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4357"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4296"/>
    <dbReference type="OrthoDB" id="2089325at2"/>
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    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595262" evidence="1">
        <location>
            <begin position="31"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="154" mass="18499" checksum="7D52B0E7D99FCEBE" modified="2016-02-17" version="1">MTALSRWFAPVALAAGLGAAAFALPAPARADDLTRVIVDIADVIVRNNTPYWRYGNYGYNDRLIVVRDRWGRPTYYRNAPRYVDYRYRPAPPPRYYANDRRYYDRDCNRHGKCRTTYYDARYDRRHDNRWDNRYYDRGRGHGHGNGRWRDRHDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMH0</accession>
    <name>A0A0S2DMH0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aminopeptidase P family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Creatinase/prolidase N-terminal domain/metallopeptidase family M24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_22470</name>
        <name evidence="3" type="ORF">GLE_4606</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW27998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949176.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4606"/>
    <dbReference type="EnsemblBacteria" id="ALN59947">
        <property type="protein sequence ID" value="ALN59947"/>
        <property type="gene ID" value="GLE_4606"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4606"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4541"/>
    <dbReference type="OMA" id="IHEWPYL"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase_N" evidence="2">
        <location>
            <begin position="37"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M24" evidence="1">
        <location>
            <begin position="177"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="403" mass="43373" checksum="58AEB2EBF697C3AA" modified="2016-02-17" version="1">MNAAAQIGGLTLETARAQLAPWTQRAPAIGAEEYQQRLERARALMRAHGFDALLVSAGASLRYFAGVPWGASERLVALLLTLDGDPLLVCPAFEAGSLAHALKIPAQARFWEEHEDPHALVAAALRERGARRLALDPGAAFAIFTGLRAAAPQLELGDAAAIVDGCRARKSPAELALMQQATTMTLQVHRLAAGLAEEGVSTATMRRFIDEAHRALGADNGSTFCIVQFGRATAFPHGIPGEQQLREGELVLIDTGCAVQGYHSDITRTYICGRADDDQRRIWDLEHAAQRAAFEAVRPGVSGEAVDDAARAVLQRGGLGPDYRLPGLPHRTGHGCGLSVHEAPYLVRGNRVGLEVGNCCSNEPMIVVPERFGVRLEDHFFVTEDGARWFTEPSVAIDRPFAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMI4</accession>
    <name>A0A0S2DMI4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">6-phosphogluconate dehydrogenase (Decarboxylating)</fullName>
            <ecNumber evidence="6">1.1.1.44</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Decarboxylating 6-phosphogluconate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">gnd</name>
        <name evidence="7" type="ORF">BV903_11755</name>
        <name evidence="8" type="ORF">FE772_21375</name>
        <name evidence="6" type="ORF">GLE_4375</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">C3</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">YC36</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; pentose phosphate pathway.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 6-phosphogluconate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.44" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000028">
        <property type="protein sequence ID" value="OPD63720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949001.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000028.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4375"/>
    <dbReference type="EnsemblBacteria" id="ALN59716">
        <property type="protein sequence ID" value="ALN59716"/>
        <property type="gene ID" value="GLE_4375"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63720">
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        <property type="gene ID" value="BV903_11755"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProt"/>
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        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="3-OH-isobutyrate_DH-rel_CS"/>
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        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
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        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Pgluconate_DH"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="gnd_rel"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
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        <location>
            <begin position="168"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD63720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW27814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="300" mass="31837" checksum="C21D2DC8D8C720E6" modified="2016-02-17" version="1">MELGMVGLGRMGANMAERLVRGGHTVVGFDPGAAAREQAAARGIGAAASLAELVAALPAPRTLWLMVPAGAVDATLAELRPLLAAGDTVVDGGNSNYKDTVRRAGELLAHDLHYVDSGTSGGVWGLQEGYSLMIGGEEAAVERLRPIFETLAPAAERGWGRVGPSGAGHFTKMIHNGIEYGMMQAYAEGFAILGRKAEFGLDLHQIAQIWRHGSVVRSWLLDLSADALGKNPDLQGIAPYVEDSGEGRWTVAEAIDLDVSAPVITASLMERLRSREKDSFADKLLAAMRNEFGGHAIRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMM0</accession>
    <name>A0A0S2DMM0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4506</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949106.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4506"/>
    <dbReference type="EnsemblBacteria" id="ALN59847">
        <property type="protein sequence ID" value="ALN59847"/>
        <property type="gene ID" value="GLE_4506"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4506"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4442"/>
    <dbReference type="OMA" id="QNDDTVA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01839">
        <property type="entry name" value="FG-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595392" evidence="2">
        <location>
            <begin position="21"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="369" mass="38331" checksum="08148513CED17DF8" modified="2016-02-17" version="1">MDYKAIKTLAFMAGMMPSIAAASGYTLQPLSTTPVNGAATSVVVEDFNADGRKDVAVLSTYNRQYHYISVFLQNASGGLSSPTVHTFDPARARALATTDLNHDGIKDFVVAHAEGVTLLTANGSGGFAAHTQAGQSWNLELAVADFDHDGNVDVANIDDVSNVMVLFGDGLGGVARSSQFAGTGTAGIDFQAGDLNGDGWSDLAFTDGSNGVYVAYNDASGGFLPPSELSDRPVNNLVAADIDGSGNTDLAATGSTSANPKSVFLFFQRTSGQLYLDHTLPTNGTFGAVSAADLDRDGKADLFAAPFGGNALEYYLQSSPMVWVKKTVATPDSGYDLAAGDIDGDGCTDVAIADYYQDLVLLKGHDCAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMN8</accession>
    <name>A0A0S2DMN8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">CaCA family Na+/Ca+ antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_4300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948946.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4300"/>
    <dbReference type="EnsemblBacteria" id="ALN59641">
        <property type="protein sequence ID" value="ALN59641"/>
        <property type="gene ID" value="GLE_4300"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4300"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4239"/>
    <dbReference type="OMA" id="TRDYGVM"/>
    <dbReference type="OrthoDB" id="804531at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004481">
        <property type="entry name" value="K/Na/Ca-exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10846">
        <property type="entry name" value="PTHR10846"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="288"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="319"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="5"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="211"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="337" mass="34120" checksum="D513C4E706F8D9D6" modified="2016-02-17" version="1">MLEAVGLFVLGLLLLALGGDSVVKGASGLAQRLGISPFAAGLVLVAFATSLPELAVNLQAVVRGQQALALGNAVGSNIVNFGLTLGLAALAAPLTVRWRALAPLLLVLLLGTVGVIGLGLDGALSRGEGLAMLAVFVAVVVFATVRTRHEKPEVQDAIAAFAQTQTHLGLNLIRLLIAAVLLHLGAYLIVGGHGLWSLHAPLPAAAGGFGSPNAAIIGAALGLSPLLAGLLPVAIGTALPEAAAAVAAARRGQGEIVVGHVIGSSLFNLLFVLGGMAALRTLPLPASFVRFELPAAAVFALMLYPMLRGDLRISRREGAVLVLALLAWIGLELAMLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMN9</accession>
    <name>A0A0S2DMN9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Exodeoxyribonuclease V</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">recBCD</name>
        <name evidence="1" type="ORF">GLE_4456</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949069.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59797">
        <property type="protein sequence ID" value="ALN59797"/>
        <property type="gene ID" value="GLE_4456"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4456"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4393"/>
    <dbReference type="OMA" id="YKRELPC"/>
    <dbReference type="OrthoDB" id="1681607at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007581">
        <property type="entry name" value="Endonuclease-V"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04493">
        <property type="entry name" value="Endonuclease_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="164" mass="17315" checksum="9183C5569B8F7CA2" modified="2016-02-17" version="1">MILATDVHYFDGRARAAGVLFADWSDALAAATLTADIDAVADYQPGAFYRRELPCLAALLAKLDAPPECIVVDGHAWLDGAGRPGLGAQLWESLQRRIAVVGVAKTRFVDTPAEAEVLRGGARPLYVTAAGMEPALARAAVARMAGAHRLPDLLKQADRLARGG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2022-05-25" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN74</accession>
    <name>PROT2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable serine protease FE772_23065</fullName>
            <ecNumber evidence="5">3.4.21.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Trypsin-like protease 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FE772_23065</name>
        <name evidence="3" type="ORF">Ga0399710_4915</name>
        <name evidence="6" type="ORF">GLE_4745</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="journal article" date="2015" name="BMC Genomics" volume="16" first="991" last="991">
            <title>Comparative genomics and metabolic profiling of the genus Lysobacter.</title>
            <authorList>
                <person name="de Bruijn I."/>
                <person name="Cheng X."/>
                <person name="de Jager V."/>
                <person name="Exposito R.G."/>
                <person name="Watrous J."/>
                <person name="Patel N."/>
                <person name="Postma J."/>
                <person name="Dorrestein P.C."/>
                <person name="Kobayashi D."/>
                <person name="Raaijmakers J.M."/>
            </authorList>
            <dbReference type="PubMed" id="26597042"/>
            <dbReference type="DOI" id="10.1186/s12864-015-2191-z"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="journal article" date="2019" name="Appl. Environ. Microbiol." volume="85" first="0" last="0">
            <title>Interspecies and Intraspecies Signals Synergistically Regulate Lysobacter enzymogenes Twitching Motility.</title>
            <authorList>
                <person name="Feng T."/>
                <person name="Han Y."/>
                <person name="Li B."/>
                <person name="Li Z."/>
                <person name="Yu Y."/>
                <person name="Sun Q."/>
                <person name="Li X."/>
                <person name="Du L."/>
                <person name="Zhang X.H."/>
                <person name="Wang Y."/>
            </authorList>
            <dbReference type="PubMed" id="31540995"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>YC36</strain>
        </source>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2022" name="Science" volume="375" first="221" last="225">
            <title>Bacterial gasdermins reveal an ancient mechanism of cell death.</title>
            <authorList>
                <person name="Johnson A.G."/>
                <person name="Wein T."/>
                <person name="Mayer M.L."/>
                <person name="Duncan-Lowey B."/>
                <person name="Yirmiya E."/>
                <person name="Oppenheimer-Shaanan Y."/>
                <person name="Amitai G."/>
                <person name="Sorek R."/>
                <person name="Kranzusch P.J."/>
            </authorList>
            <dbReference type="PubMed" id="35025633"/>
            <dbReference type="DOI" id="10.1126/science.abj8432"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>MUTAGENESIS OF SER-296</scope>
        <source>
            <strain>YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Possibly a dedicated protease for substrate gasdermin bGSDM; cleaves the bGSDM precursor, releasing the pore-forming moiety, which integrates into the membrane and triggers cell death. Involved in defense against bacteriophages. When this probable 4 gene operon (bGSDM-FE772_23060-FE772_23065-FE772_23070) is inserted into E.coli it provides nearly 100-fold protection against phages T5 and T6 and about 8-fold against phage T4. The operon without bGSDM no longer protects against phage.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase S1 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949282.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4745"/>
    <dbReference type="EnsemblBacteria" id="ALN60086">
        <property type="protein sequence ID" value="ALN60086"/>
        <property type="gene ID" value="GLE_4745"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4745"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4679"/>
    <dbReference type="OrthoDB" id="1468733at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword id="KW-0051">Antiviral defense</keyword>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0645">Protease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0720">Serine protease</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_0000455585" description="Probable serine protease FE772_23065">
        <location>
            <begin position="1"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="532"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="mutagenesis site" description="4-gene operon no longer protects against phage." evidence="2">
        <original>S</original>
        <variation>A</variation>
        <location>
            <position position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1"/>
    <evidence type="ECO:0000269" key="2">
        <source>
            <dbReference type="PubMed" id="35025633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="3">
        <source>
            <dbReference type="PubMed" id="35025633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="4"/>
    <evidence type="ECO:0000305" key="5">
        <source>
            <dbReference type="PubMed" id="31540995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000312" key="6">
        <source>
            <dbReference type="EMBL" id="ALN60086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000312" key="7">
        <source>
            <dbReference type="EMBL" id="QCW28097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000312" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000312" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN60086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="641" mass="69571" checksum="559DE1AF8D083B97" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN75</accession>
    <name>A0A0S2DN75_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GlcNAc-PI de-N-acetylase family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">PIG-L family deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_20740</name>
        <name evidence="1" type="ORF">GLE_4235</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948891.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4235"/>
    <dbReference type="EnsemblBacteria" id="ALN59576">
        <property type="protein sequence ID" value="ALN59576"/>
        <property type="gene ID" value="GLE_4235"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4235"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4176"/>
    <dbReference type="OMA" id="GWRINAF"/>
    <dbReference type="OrthoDB" id="1502251at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="SSF102588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="257" mass="28264" checksum="7C2CDB63F35B1E0C" modified="2016-02-17" version="1">MRSDVSAQPAPPLLAVFVHPDDEFAAFPWLRRALAEGRAVDAVWLTDGGWGGQDMARRRAESVAVLSALGMDPARMHFCGEQWGIADGGLHLRLDEAVPRALERFGSVRGGEVLMPAWEGGHHDHDAGHLVGIAVAQARGARMWQFSLYHGEGLRGPWFKVLSPLPANGASEVLPTTLGERLRYAAACLAYRSQWKSFVGLLPFYLWRMLGADAFRRQPVDPRRTAQRPHAGPMLYERRGGPSWAEFAAATAAHRQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN80</accession>
    <name>A0A0S2DN80_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">D-alanyl-D-alanine dipeptidase</fullName>
            <shortName evidence="3 4">D-Ala-D-Ala dipeptidase</shortName>
            <ecNumber evidence="3 4">3.4.13.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">ddpX</name>
        <name evidence="5" type="ORF">GLE_4596</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3 4">
            <text>D-alanyl-D-alanine + H2O = 2 D-alanine</text>
            <dbReference type="Rhea" id="RHEA:20661"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="EC" id="3.4.13.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the peptidase M15D family.</text>
    </comment>
    <dbReference type="EC" id="3.4.13.22" evidence="3 4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4596"/>
    <dbReference type="EnsemblBacteria" id="ALN59937">
        <property type="protein sequence ID" value="ALN59937"/>
        <property type="gene ID" value="GLE_4596"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4596"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4531"/>
    <dbReference type="OMA" id="IRTEWWH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01924">
        <property type="entry name" value="A_A_dipeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000755">
        <property type="entry name" value="A_A_dipeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01427">
        <property type="entry name" value="Peptidase_M15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026671">
        <property type="entry name" value="AA_dipeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 4 5" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="3 4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3 4" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
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        <location>
            <position position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR026671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="265" mass="28895" checksum="1A1E6F1AFCFE8748" modified="2016-02-17" version="1">MKTWRSRASAIAVEACALLVLIGCVAAVRSPQARTGPAPSPAPAAAAPVAAVAPTISTAQDAAAAGMVEIRSLVPDIDLEIRYAGGDNFVGRPVAGYLGAACYLHRPVAQALARVERELRAQGLRLRIYDCYRPVRAVRDFVAWAADPDDQKTKPRYYPTLDKSRLLGDYISPTSGHSRGATLDLTLLEPSGEGYAPLDMGTGFDFFDELAHTDAPGASLAQRGHRQRLRAAMQREGFENYPLEWWHYTFKPEPTPRTAFDFPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNM5</accession>
    <name>A0A0S2DNM5_LYSEN</name>
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        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">FE772_23120</name>
        <name evidence="2" type="ORF">GLE_4756</name>
    </gene>
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        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.21.50" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW28107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4756"/>
    <dbReference type="EnsemblBacteria" id="ALN60097">
        <property type="protein sequence ID" value="ALN60097"/>
        <property type="gene ID" value="GLE_4756"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4756"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4690"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
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    <feature type="domain" description="VWFD" evidence="1">
        <location>
            <begin position="451"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="768" mass="81761" checksum="53F50AF76B84F081" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNP6</accession>
    <name>A0A0S2DNP6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FAD dependent oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">GMC family oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Glucose-methanol-choline oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BV903_10500</name>
        <name evidence="6" type="ORF">FE772_23475</name>
        <name evidence="4" type="ORF">GLE_4831</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">C3</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000023">
        <property type="protein sequence ID" value="OPD64011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949346.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4831"/>
    <dbReference type="EnsemblBacteria" id="ALN60172">
        <property type="protein sequence ID" value="ALN60172"/>
        <property type="gene ID" value="GLE_4831"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64011">
        <property type="protein sequence ID" value="OPD64011"/>
        <property type="gene ID" value="BV903_10500"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4831"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4762"/>
    <dbReference type="OMA" id="MAPYPST"/>
    <dbReference type="OrthoDB" id="365211at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="264"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="GMC_oxred_C" evidence="3">
        <location>
            <begin position="504"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD64011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW28168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="656" mass="71144" checksum="0912CD2453D3F64C" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNW4</accession>
    <name>A0A0S2DNW4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4790"/>
    <dbReference type="EnsemblBacteria" id="ALN60131">
        <property type="protein sequence ID" value="ALN60131"/>
        <property type="gene ID" value="GLE_4790"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4790"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4723"/>
    <dbReference type="OMA" id="WHFARGK"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005271">
        <property type="entry name" value="CmoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861:SF2">
        <property type="entry name" value="PTHR43861:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="217" mass="23713" checksum="E70CFBD01D659776" modified="2016-02-17" version="1">MRIARAYLPEHPLGNRWDYYYSRAKLGSDPLYPGVSQALRGTRAPLLDLGCGLGLLAHTLRADGIALPYRGVDSDAAKIRRAGRAAARVGLDGAGFAVMDLSRELPEHRGSVAILDVLQFIPYPAQARAIDAMIAMLVPGARLVIRTGLDDGTGRARVTRAVDLFSRALGWMNATPRYYPDGEALRARLQAAGLRVEFAPMFGRTPFNNWRIVAARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP01</accession>
    <name>A0A0S2DP01_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_18305</name>
        <name evidence="2" type="ORF">GLE_5033</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000049">
        <property type="protein sequence ID" value="OPD62488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5033"/>
    <dbReference type="EnsemblBacteria" id="ALN60374">
        <property type="protein sequence ID" value="ALN60374"/>
        <property type="gene ID" value="GLE_5033"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62488">
        <property type="protein sequence ID" value="OPD62488"/>
        <property type="gene ID" value="BV903_18305"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5033"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4961"/>
    <dbReference type="OMA" id="EIWRWNP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595484" evidence="1">
        <location>
            <begin position="19"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="140" mass="15929" checksum="2429CFE1A721B814" modified="2016-02-17" version="1">MRLVKYLLLSCLFAFAVAGCQTTGTQNNRLTEMQYAYSAAVRWGDFEGAANLIKPELRKQLAPTPMQLERYKQIQVSGYNDVGSEVDKKKGTAARVVNIGVINRHTMAERSVRYIEAWEWDPVAKTWWLIGGLPDFWQGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP28</accession>
    <name>A0A0S2DP28_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">EamA family transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Integral membrane protein DUF6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_23575</name>
        <name evidence="3" type="ORF">GLE_4854</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949362.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4854"/>
    <dbReference type="EnsemblBacteria" id="ALN60195">
        <property type="protein sequence ID" value="ALN60195"/>
        <property type="gene ID" value="GLE_4854"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4854"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4784"/>
    <dbReference type="OMA" id="VNSDFAT"/>
    <dbReference type="OrthoDB" id="1668457at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="7"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="144" mass="15371" checksum="3F2270C7ECB81DF0" modified="2016-02-17" version="1">MTSFPAWAIWALLSAVFAALTAVLAKVGVQGISADYATLVRTVVILCVLALLVPLSRQWLDPRSLPARSLLFLALSGLATGASWLCYYRALQLGEVAQVAPVDKLSVVLAALFAVAFLGERPSPRDWLGLLLVGGGVLVLAWRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPC0</accession>
    <name>A0A0S2DPC0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA (cytidine(34)-2'-O)-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.207</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmL</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">trmL</name>
        <name evidence="7" type="ORF">FE772_24315</name>
        <name evidence="6" type="ORF">GLE_5016</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>5-carboxymethylaminomethyluridine(34) in tRNA(Leu) + S-adenosyl-L-methionine = 5-carboxymethylaminomethyl-2'-O-methyluridine(34) in tRNA(Leu) + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43088"/>
            <dbReference type="Rhea" id="RHEA-COMP:10333"/>
            <dbReference type="Rhea" id="RHEA-COMP:10334"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74508"/>
            <dbReference type="ChEBI" id="CHEBI:74511"/>
            <dbReference type="EC" id="2.1.1.207"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>cytidine(34) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(34) in tRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43084"/>
            <dbReference type="Rhea" id="RHEA-COMP:10331"/>
            <dbReference type="Rhea" id="RHEA-COMP:10332"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.207"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.207" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949488.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5016"/>
    <dbReference type="EnsemblBacteria" id="ALN60357">
        <property type="protein sequence ID" value="ALN60357"/>
        <property type="gene ID" value="GLE_5016"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5016"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4944"/>
    <dbReference type="OMA" id="AGLDYWH"/>
    <dbReference type="OrthoDB" id="1578095at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008175">
        <property type="term" value="F:tRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18094">
        <property type="entry name" value="SpoU-like_TrmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01885">
        <property type="entry name" value="tRNA_methyltr_TrmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016914">
        <property type="entry name" value="tRNA_cyt/urid_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42971">
        <property type="entry name" value="PTHR42971"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029256">
        <property type="entry name" value="SpoU_TrmH_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 3 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="5">
        <location>
            <begin position="2"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3 4">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 4">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 4">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 4">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR029256-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN60357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW28306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="159" mass="17268" checksum="981E10AE49745229" modified="2016-02-17" version="1">MFNVILFQPEIPPNTGNVIRLCANTGAALHLIAPLGFTLEDKQLKRAGLDYHEYASLQVHDGLDAALAAIAAAQGAPPRLFALSTRGRERFDAPRYAAGDAFLFGPETRGLPQDVLDAVPQAQRLRLPMRPDNRSLNLSNSVAVVVFEAWRQFGFAGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPD3</accession>
    <name>A0A0S2DPD3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transporter, major facilitator family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_5095</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5095"/>
    <dbReference type="EnsemblBacteria" id="ALN60436">
        <property type="protein sequence ID" value="ALN60436"/>
        <property type="gene ID" value="GLE_5095"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5095"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5020"/>
    <dbReference type="OMA" id="MQGNNLG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="368"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="402"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="41"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN60436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="431" mass="43526" checksum="29FB8E370C8B50FD" modified="2016-02-17" version="1">MFPTRSARMKSTSLPFSAQPPSDTAPDRPAQADAASTDWRAVAAVFGAGLIAALQVGKTAIALPALRADLGLDLRAGGWLMAVFGLLGLFASVPAGALVARLGDRRLQVAGLAAMALGSALGSQADSLTALMATRVLEGAGFLLFAVAGASVLQRLSQARDRAVVFAIWSCYMPAGMALALATGAALDGWRGYWELNALLCAAAALALHWAVRAPSAQAARAAAARPWRAIAADAWAVAGARGPLLLALAFALYALQFYALLSFLPTLLMQRMQVDAAGAGLLSGAAIGANVLGNLAAGALLRRGARRWRLIALASATMGLSAAAVFALPLPATVAYSLCVLFALAGGLLPASTIGGAAELERDPGRIAIAVGLLMQGSYLGQVIGPSLFGSVVQAAGWPAAAWPVGLAALGAVAAAVALRRSFAAEGGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPL8</accession>
    <name>A0A0S2DPL8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome B561</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Cytochrome b</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BV903_08020</name>
        <name evidence="4" type="ORF">GLE_5205</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000016">
        <property type="protein sequence ID" value="OPD64481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949633.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5205"/>
    <dbReference type="EnsemblBacteria" id="ALN60546">
        <property type="protein sequence ID" value="ALN60546"/>
        <property type="gene ID" value="GLE_5205"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64481">
        <property type="protein sequence ID" value="OPD64481"/>
        <property type="gene ID" value="BV903_08020"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5205"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5124"/>
    <dbReference type="OMA" id="RLLHWVM"/>
    <dbReference type="OrthoDB" id="1940783at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011577">
        <property type="entry name" value="Cyt_b561_bac/Ni-Hgenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01292">
        <property type="entry name" value="Ni_hydr_CYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="SSF81342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="Ni_hydr_CYTB" evidence="3">
        <location>
            <begin position="12"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD64481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="185" mass="20587" checksum="515C92547FEC3E0E" modified="2016-02-17" version="1">MNRETATTMFWWPARVLHWLMAAMILAMLFVGAGLVASVSERHAWLLALHKPLGIAILLLAVLRLALRLRHRPPPLPRDLAPAVRLAAHASHWLLYALMLAMPLIGWAMLSAGGYPVELGAGVRLPPIAPFDPSWFAALRWLHRALAYALFALVLAHLGAALYHGLIRRDGVLRSMLWRQRSAPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPR3</accession>
    <name>A0A0S2DPR3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phenylacetaldehyde dehydrogenase (PAD)</fullName>
            <ecNumber evidence="6">1.2.1.39</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_5305</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.39" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949706.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5305"/>
    <dbReference type="EnsemblBacteria" id="ALN60646">
        <property type="protein sequence ID" value="ALN60646"/>
        <property type="gene ID" value="GLE_5305"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5305"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5223"/>
    <dbReference type="OMA" id="PAAWMNN"/>
    <dbReference type="OrthoDB" id="744602at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008957">
        <property type="term" value="F:phenylacetaldehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="5">
        <location>
            <begin position="30"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN60646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="495" mass="52592" checksum="CFFF933122EDBEC0" modified="2016-02-17" version="1">MARPDLLPEVAAFLQRAHGHFIDGRAVPGEGARLAIVDPATAEPIAEVAAAGAAEIDAAVAAAQRAFAGDWGRAMPAQRAHCLLRLADLIEAHGDELAQIETLQSGKLLGLARGFEIAQAAAFLRHYAGAATRLHGETIAPSIPSFHDERYTAFTRREPVGAVAGIVPWNFSILIAVWKFASALATGCTSVIKPSEFTPLTMLRIAELALEAGIPPGALNVVCGGGDSGRLLCAHPGIAKISFTGSVATGLQVGRAAFDGRLVRTTLELGGKNPVAFLPDVPIERMLGGIMEAGFLHQGQICAAGERFFIHRSRIDETLEALAATLRTLRIGDPMDPTTQFGPLANRPHLDKIAALFRQARGDGTRIVCGGETLDRPGFFVAPTALRVDRADAPLLHQETFGPIGTFLAYDDEDELPDLLNGTPYGLAASVWTQDIAKALRLVPQVRAGTVWINMHTLLDPAVPFGGAKQSGVGREFGAAFVDDYTELKSVMIRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPS6</accession>
    <name>A0A0S2DPS6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OMP_b-brl domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_24585</name>
        <name evidence="3" type="ORF">GLE_5072</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5072"/>
    <dbReference type="EnsemblBacteria" id="ALN60413">
        <property type="protein sequence ID" value="ALN60413"/>
        <property type="gene ID" value="GLE_5072"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5072"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4999"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036709">
        <property type="entry name" value="Autotransporte_beta_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103515">
        <property type="entry name" value="SSF103515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242279" description="OMP_b-brl domain-containing protein" evidence="1">
        <location>
            <begin position="33"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="2">
        <location>
            <begin position="19"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="226" mass="24182" checksum="ADA84D3E53AB64EA" modified="2016-02-17" version="1">MSVSSKSVVSKSVLSKSALAAALCLLAVPAPAQERSHTYLDAGYVAQKLKSGSSNPLLRLDDIDVDGAYAAGSVELGSQLFLTGSLHKGSGDNRLRAGQDVLAEFDVDAQQAGIGLGYYRALGERAEWTAEVGYQNTRIEFENRALRFSEKIDGNDYRVSLGLRGDLASNLEGWARVNYIDGDVYEREFSGTVGALLKFNAMWGLSAEASAGAGNQRYLVGVRASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-06-17" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ49</accession>
    <name>A0A0S2DQ49_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_25550</name>
        <name evidence="1" type="ORF">GLE_5283</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949689.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60624">
        <property type="protein sequence ID" value="ALN60624"/>
        <property type="gene ID" value="GLE_5283"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5283"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5201"/>
    <dbReference type="OMA" id="HADEPNF"/>
    <dbReference type="OrthoDB" id="1836022at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="166" mass="17781" checksum="4273DF77F10FE9BF" modified="2016-02-17" version="1">MDLHATPLPPAAAAAAAAPPCFAGLPTPDGENFHALCEFCQRHRVQTLAALPWAAAEIAESCGFAAMLRLVHRHGGRRVYLPRGRGACASRLGLDAELDAAVHRRLLDRASAAGTIEIPSAWGVFVALRRVAIRAAVRAGCDQREIAHAFGVTERHLRREVDALRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQB3</accession>
    <name>A0A0S2DQB3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_00535</name>
        <name evidence="2" type="ORF">GLE_5463</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949827.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60804">
        <property type="protein sequence ID" value="ALN60804"/>
        <property type="gene ID" value="GLE_5463"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5463"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5378"/>
    <dbReference type="OMA" id="ACGITQA"/>
    <dbReference type="OrthoDB" id="2184100at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726827" evidence="1">
        <location>
            <begin position="21"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="178" mass="17916" checksum="1B414BF4269FADB4" modified="2016-02-17" version="1">MKIAILVGPLLLAAAAGAHAQAPDAAREALRQAATGDAFRIGYTQFRLAPDGLVSTAAQSAGSQAVRVGDYAVQVRPAAARSARAVAAKPRLVAAVGDDGKAVVVTSTLNVYHRDPAALQAAARASGGTLVYSSVAGGNGRIEFDSVDAAMKAMAKIQAIAGIKEVAPEIIEGDDAPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQR3</accession>
    <name>A0A0S2DQR3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Homogentisate 1,2-dioxygenase</fullName>
            <shortName evidence="6">HGDO</shortName>
            <ecNumber evidence="6">1.13.11.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Homogentisate oxygenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Homogentisic acid oxidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Homogentisicase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">hmgA</name>
        <name evidence="9" type="ORF">FE772_25610</name>
        <name evidence="8" type="ORF">GLE_5298</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>homogentisate + O2 = 4-maleylacetoacetate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15449"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16169"/>
            <dbReference type="ChEBI" id="CHEBI:17105"/>
            <dbReference type="EC" id="1.13.11.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 4/6.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Hexamer; dimer of trimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the homogentisate dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.5" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949701.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5298"/>
    <dbReference type="EnsemblBacteria" id="ALN60639">
        <property type="protein sequence ID" value="ALN60639"/>
        <property type="gene ID" value="GLE_5298"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5298"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5216"/>
    <dbReference type="OrthoDB" id="193687at2"/>
    <dbReference type="UniPathway" id="UPA00139">
        <property type="reaction ID" value="UER00339"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004411">
        <property type="term" value="F:homogentisate 1,2-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006572">
        <property type="term" value="P:tyrosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00334">
        <property type="entry name" value="Homogentis_dioxygen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005708">
        <property type="entry name" value="Homogentis_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022950">
        <property type="entry name" value="Homogentis_dOase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11056">
        <property type="entry name" value="PTHR11056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04209">
        <property type="entry name" value="HgmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01015">
        <property type="entry name" value="hmgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 6" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="285"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="364"/>
        </location>
        <ligand>
            <name>homogentisate</name>
            <dbReference type="ChEBI" id="CHEBI:16169"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="382"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN60639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW28520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="433" mass="48256" checksum="1D87304712B0371B" modified="2016-02-17" version="1">MNYANGFGNHHSSEAVPGALPLGQNSPQRVPFGLYAEQWSGSAFTAPRADNRRSWLYRLRPTAQHPPYVPYARDSLLRSGPFDEEPASPNRLRWDPLPLPQAPTDFIDGLVSYGGNGDVAAGDGIGIHLYAINAPMRGRAFCCADGEWLIVPQQGRLRVDTELGRIELEPQQIAVLPRGLRYRVEPLDGSARGYVCENYGAPLRLPELGPIGANGLANPRDFETPLAWFEDRDEPTEVVQKFQGRLWTMELPHSPFDVVAWHGNLAPYRYDLRRFNTINTVSFDHPDPSIFTVLTAPSDTPGTANIDFVIFPPRWMVAERSFRPPWFHRNVMSEFMGLIHGEYDAKAGGFAPAGASLHNQMSGHGPDRASYERAIAADLAPHKIDGAMAFMFESRRVIRPTRFAVRTPLSQLDYDECWSDLDKARLAPAQVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQS1</accession>
    <name>A0A0S2DQS1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutathionylspermidine synthase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Glutathionylspermidine synthase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_00415</name>
        <name evidence="2" type="ORF">GLE_5436</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949807.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5436"/>
    <dbReference type="EnsemblBacteria" id="ALN60777">
        <property type="protein sequence ID" value="ALN60777"/>
        <property type="gene ID" value="GLE_5436"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5436"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5352"/>
    <dbReference type="OMA" id="DEIYWDE"/>
    <dbReference type="OrthoDB" id="692145at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005494">
        <property type="entry name" value="GSPS_pre-ATP-grasp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03738">
        <property type="entry name" value="GSP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GSP_synth" evidence="1">
        <location>
            <begin position="12"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="395" mass="44956" checksum="93F147D264BCAF98" modified="2016-02-17" version="1">MKRIVVPERPDWREQAESLGFRFHTIDGAPYWDERAYYAFGLRQIEDEIEQPTQELHDMAMALVDEVVGSERLLERLAIPREYWDWIADSWRRGEPHLYGRMDLAYDGRGPAKLYELNYDTPTSLYEAAYFQWLWLEQSIARGALGEGSDQYNRIQELLIETFGALARDKRIATPVHFAAVEDSPEDQGTVRYLRDCAEQAGVDTLELSIEGIGLSREGYFTDGDDRVIRTLFKLYPLEWMFVEEYGPKLAGSRVQLIEPAWKAILSNKGVLPLLWERHAGHPNLLEAHFEDADPGELAPGWVRKPLFSREGANIELVGLDGERLRSDGPYQDGPTIRQALHPLPRFDGADGEPNYPLIGSWVVADQAAGMGIREDEGPITQDSSRFLPHAIVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DRA1</accession>
    <name>A0A0S2DRA1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5506</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60847">
        <property type="protein sequence ID" value="ALN60847"/>
        <property type="gene ID" value="GLE_5506"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5506"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5421"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="95" mass="10974" checksum="40217B02EE186E8E" modified="2016-02-17" version="1">MCQPTQERIMDLNPELEKIVAEFEEEFGRLPNVASPEKLFAKFRKWSDRNANSSDDMRLFGMHLAEEGYLPCRNADGSLCFVYLGYEPPRNGERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA95</accession>
    <name>A0A0S2DA95_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_01470</name>
        <name evidence="3" type="ORF">GLE_0109</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945801.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0109"/>
    <dbReference type="EnsemblBacteria" id="ALN55468">
        <property type="protein sequence ID" value="ALN55468"/>
        <property type="gene ID" value="GLE_0109"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0109"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.112"/>
    <dbReference type="OMA" id="DASWIFI"/>
    <dbReference type="OrthoDB" id="985580at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="271"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="348"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="436" mass="48573" checksum="F6A486B48150A184" modified="2016-02-17" version="1">MSATAPISAPSPDSAAAPLQPADSDRLSPGAWREIPLLSARLLWRHWPALAFWFFAQRVCYDLLMDLAVKLGERSLLLSFAALSVLIVTQLAGTIFMFQSLRPSLPMLAGGATTPDTRPDPRAVRKQWITALAIALLPFFAYYVGWGLMESLRRYFTTAYIFGVWEREDLRHVLTLKGLWIALAVAWAVRWFSKRRAAASGHASWSVLATVCEAYWVFVGVAAIGQMVKAGQEWWHQRAVYVAVSDWWESPTALFKLLAPAKRALAPAWEFVATAAGAVALPLIWLAITAIIYGIDLRKAQRIDAADAPLERAVARFKAMHFTLRMLADKASAGWTSKGVPVVNSLRLVLRAGLPALLTLCVCWQLLAYLDSWSWRWMQQWVGPTDPGWQRVQGQIYAVFLNTPLSFRTSLLTDVLRVVLLAATFDRAIARLPRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAN9</accession>
    <name>A0A0S2DAN9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AraC family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">D9T17_01685</name>
        <name evidence="4" type="ORF">FE772_02005</name>
        <name evidence="3" type="ORF">GLE_0235</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000005">
        <property type="protein sequence ID" value="ROU09054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945890.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000005.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0235"/>
    <dbReference type="EnsemblBacteria" id="ALN55594">
        <property type="protein sequence ID" value="ALN55594"/>
        <property type="gene ID" value="GLE_0235"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0235"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.237"/>
    <dbReference type="OMA" id="PLYRYQL"/>
    <dbReference type="OrthoDB" id="1268974at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="175"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU09054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="276" mass="30369" checksum="1BED7E7C33E47051" modified="2016-02-17" version="1">MSGFTVHTLLKTPTVTVRDVYCPGGCKHRGPEECAAATHLVFPYRGVYVRHLGEQASVAEASQVLFFNAGEGYRVSHPIDGGDASLSLSIAEPMLREMAPKALLRDGEALAFRQPRLRIDPRAQSLAMLLRHSLRQGIAEPLEAESLALTLAQRALGPRTAHAAGASAGQQRLVERTKLVLVSDLSRRWTLAEIAAEVGVSPVYLTQVFQRVEGLPLYRYQLRLRLARALDLLGEYEDLSALGQDLGFSSHSHFSAAFQQTYGRSPSEFRQSALYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAT7</accession>
    <name>A0A0S2DAT7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF2164 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_23680</name>
        <name evidence="3" type="ORF">FE772_02245</name>
        <name evidence="1" type="ORF">GLE_0283</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000085">
        <property type="protein sequence ID" value="OPD61426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945926.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000085.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55641">
        <property type="protein sequence ID" value="ALN55641"/>
        <property type="gene ID" value="GLE_0283"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61426">
        <property type="protein sequence ID" value="OPD61426"/>
        <property type="gene ID" value="BV903_23680"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0283"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.282"/>
    <dbReference type="OMA" id="VFYNQGL"/>
    <dbReference type="OrthoDB" id="2072550at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018680">
        <property type="entry name" value="DUF2164"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09932">
        <property type="entry name" value="DUF2164"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD61426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="84" mass="9740" checksum="0130A80179EB0ACA" modified="2016-02-17" version="1">METIRFAAEEKALLVARLQRYFSEELKQSIGRFDAEFMLDFISEELGAYYYNRGVADAQAVLAAKVEDLADAVWQLERPTEFKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB35</accession>
    <name>A0A0S2DB35_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cysteine hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Isochorismatase</fullName>
            <ecNumber evidence="2">3.3.2.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_02730</name>
        <name evidence="2" type="ORF">GLE_0388</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.3.2.1" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945996.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0388"/>
    <dbReference type="EnsemblBacteria" id="ALN55746">
        <property type="protein sequence ID" value="ALN55746"/>
        <property type="gene ID" value="GLE_0388"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0388"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.385"/>
    <dbReference type="OMA" id="DAYMREY"/>
    <dbReference type="OrthoDB" id="1442962at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008908">
        <property type="term" value="F:isochorismatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="185" mass="20145" checksum="4317D66F1DB0D3A4" modified="2016-02-17" version="1">MTNVAPPQIALLIVDMFNFLDFADGQALLKQALPAARRIAALKRRFRRVGAPVIYANDNFGQWHADFRELVAVCRHESCRGAPIADLLAPEADDFYVLKPKQSAFHSTPLAVLLEHCGCREVAITGISTDVCIAATAIDAHMRDLTVRIPADCVAAPSRRRTAVALAVLKQSVHARCAQSPSLHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB40</accession>
    <name>A0A0S2DB40_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">16S rRNA (cytosine(967)-C(5))-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.176</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">16S rRNA m5C967 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">rRNA (cytosine-C(5)-)-methyltransferase RsmB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">sun</name>
        <name evidence="15" type="ORF">GLE_0358</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>cytidine(967) in 16S rRNA + S-adenosyl-L-methionine = 5-methylcytidine(967) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42748"/>
            <dbReference type="Rhea" id="RHEA-COMP:10219"/>
            <dbReference type="Rhea" id="RHEA-COMP:10220"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74483"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.176"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.176" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0358"/>
    <dbReference type="EnsemblBacteria" id="ALN55716">
        <property type="protein sequence ID" value="ALN55716"/>
        <property type="gene ID" value="GLE_0358"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0358"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.355"/>
    <dbReference type="OMA" id="RYEPVAM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008649">
        <property type="term" value="F:rRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018314">
        <property type="entry name" value="Fmu/NOL1/Nop2p_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB/NOP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035926">
        <property type="entry name" value="NusB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006027">
        <property type="entry name" value="NusB_RsmB_TIM44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004573">
        <property type="entry name" value="rRNA_ssu_MeTfrase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="PTHR22807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01029">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48013">
        <property type="entry name" value="SSF48013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00563">
        <property type="entry name" value="rsmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01153">
        <property type="entry name" value="NOL1_NOP2_SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12 15" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="8 12" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7 12 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM_MT_RSMB_NOP" evidence="14">
        <location>
            <begin position="363"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="12">
        <location>
            <begin position="453"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="61"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="12">
        <location>
            <position position="577"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="476"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="505"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="524"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ALN55716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="636" mass="68080" checksum="3519015461756BC4" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB72</accession>
    <name>A0A0S2DB72_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946025.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55783">
        <property type="protein sequence ID" value="ALN55783"/>
        <property type="gene ID" value="GLE_0425"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0425"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.422"/>
    <dbReference type="OMA" id="DISAGHE"/>
    <dbReference type="OrthoDB" id="1933465at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="327" mass="35923" checksum="F6DB1FF1B69DA826" modified="2016-02-17" version="1">MPGDDLPRMIVFAGPNGSGKSTITKSWSEEPGFPKDGYINADEIAKGMEKQYPDYHERNFRAANIAEEHRKLALESGKPFAFETVMSTPGKLAQFDEARNKGFSVDLVFVTTEHSEINKQRVGNRVAGGGHGVDAAKIVERYERAMDLLPAAVEKANTATIYDNSGREPIVVAKKLENGKMVYPQGENTPDWVKDRLQKPLEARDASRADLDKELRGRVPGADVRPADISAGHEYRGRVALMTSQHVLQHVSGTNYVLHDRSLTPAVDFAKAQKDPGFPEIDVSYKFGADGKHPPQALEATQAQGQQQAQQQAPSGQEPPQLPRSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBB4</accession>
    <name>A0A0S2DBB4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tli4_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0438</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55796">
        <property type="protein sequence ID" value="ALN55796"/>
        <property type="gene ID" value="GLE_0438"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0438"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.435"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041290">
        <property type="entry name" value="Tli4_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18426">
        <property type="entry name" value="Tli4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tli4_C" evidence="2">
        <location>
            <begin position="125"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="286" mass="31714" checksum="CE51726B829889A9" modified="2016-02-17" version="1">MSSASSFADVERDARVQAERLGLRASKRQDASDDTFDRRAGIDSRQDRSATRLIGIDSYPKSEQVAIGSHVDDAATKFQVDLYRFVDRKRYAFRTINYRASRYPQARDFLMESAGRYRPLSAGRIPGERGFCLNDGIFIDSGTPEINESFVLVVKFPKHPGLQFHLDGEALRKADRDEPSLARRADRELATLAEHGDAVRVLKRGEARYADQGGFEIAIAVNHPDLPGGGGLKYTWMAEGRVGDVVHPTLEAELMTGQGASTGLDEAEVAALWKRLMESLRIRPSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBF7</accession>
    <name>A0A0S2DBF7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">D-aminoacyl-tRNA deacylase</fullName>
            <shortName evidence="1">DTD</shortName>
            <ecNumber evidence="1">3.1.1.96</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Gly-tRNA(Ala) deacylase</fullName>
            <ecNumber evidence="1">3.1.1.-</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 2" type="primary">dtd</name>
        <name evidence="3" type="ORF">BV903_09950</name>
        <name evidence="4" type="ORF">FE772_02630</name>
        <name evidence="2" type="ORF">GLE_0367</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a D-aminoacyl-tRNA + H2O = a D-alpha-amino acid + a tRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13953"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:10124"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59871"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:79333"/>
            <dbReference type="EC" id="3.1.1.96"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>glycyl-tRNA(Ala) + H2O = glycine + H(+) + tRNA(Ala)</text>
            <dbReference type="Rhea" id="RHEA:53744"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:13640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DTD family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.96" evidence="1"/>
    <dbReference type="EC" id="3.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000022">
        <property type="protein sequence ID" value="OPD64032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945982.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000022.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0367"/>
    <dbReference type="EnsemblBacteria" id="ALN55725">
        <property type="protein sequence ID" value="ALN55725"/>
        <property type="gene ID" value="GLE_0367"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64032">
        <property type="protein sequence ID" value="OPD64032"/>
        <property type="gene ID" value="BV903_09950"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0367"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.364"/>
    <dbReference type="OMA" id="GVFQAHM"/>
    <dbReference type="OrthoDB" id="1862614at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051499">
        <property type="term" value="F:D-aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106026">
        <property type="term" value="F:Gly-tRNA(Ala) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043908">
        <property type="term" value="F:Ser(Gly)-tRNA(Ala) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019478">
        <property type="term" value="P:D-amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00563">
        <property type="entry name" value="Dtyr_deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00518">
        <property type="entry name" value="Deacylase_Dtd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003732">
        <property type="entry name" value="Daa-tRNA_deacyls_DTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023509">
        <property type="entry name" value="DTD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10472">
        <property type="entry name" value="PTHR10472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02580">
        <property type="entry name" value="Tyr_Deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69500">
        <property type="entry name" value="SSF69500"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00256">
        <property type="entry name" value="TIGR00256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0820">tRNA-binding</keyword>
    <feature type="short sequence motif" description="Gly-cisPro motif, important for rejection of L-amino acids" evidence="1">
        <location>
            <begin position="138"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="146" mass="15123" checksum="032678F2A5CD6AAE" modified="2016-02-17" version="1">MLSLIQRVTQAAVTVDGETVGAIGPGLLALVGIEPGDGEAQIARMADRLLGYRVFADEAGRMNRGLADTGGGLLLVSQFTLAADTSSGMRPGFSTAAAPGLAEPLFNRLLETCRQRHGGGVETGRFGAHMVVSLVNDGPVTFLLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBG0</accession>
    <name>A0A0S2DBG0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0514</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55872">
        <property type="protein sequence ID" value="ALN55872"/>
        <property type="gene ID" value="GLE_0514"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0514"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.509"/>
    <dbReference type="OMA" id="SCVAKQV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="80"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="203" mass="22127" checksum="34A2CC3B6D4C7161" modified="2016-02-17" version="1">MQGGARRRPARAIAPMLPARAGARPCHRSRRLSCLLSYASHARRSRARAGLSASGDSGSIAAVNDSPIDPVHLRDLARLRKVRDRIDREYAQPLDVEALARGAHMSAGHLSRQFRAAYGESPYSYLMTRRIERAMALLRAGGLSVTEVCFAVGCSSLGTFSTRFAELVGMPPSVYQRQHADATDGMPACVAKQVTRPIRNREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBI6</accession>
    <name>A0A0S2DBI6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DUF2029 domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FE772_03400</name>
        <name evidence="8" type="ORF">GLE_0537</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glycosyltransferase 87 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946107.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55895">
        <property type="protein sequence ID" value="ALN55895"/>
        <property type="gene ID" value="GLE_0537"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0537"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.531"/>
    <dbReference type="OMA" id="TSRESTW"/>
    <dbReference type="OrthoDB" id="410471at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018584">
        <property type="entry name" value="GT87"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09594">
        <property type="entry name" value="GT87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="262"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="446"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="470"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN55895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW24860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="537" mass="56929" checksum="EBC7AC09D96F28E4" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBT2</accession>
    <name>A0A0S2DBT2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cystathionine beta-lyase</fullName>
            <ecNumber evidence="6">4.4.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">metC</name>
        <name evidence="6" type="ORF">GLE_0628</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + L,L-cystathionine = L-homocysteine + NH4(+) + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:13965"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58161"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.8" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0628"/>
    <dbReference type="EnsemblBacteria" id="ALN55986">
        <property type="protein sequence ID" value="ALN55986"/>
        <property type="gene ID" value="GLE_0628"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0628"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.618"/>
    <dbReference type="OMA" id="VALDNTY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004121">
        <property type="term" value="F:cystathionine beta-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006233">
        <property type="entry name" value="Cys_b_lyase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43500">
        <property type="entry name" value="PTHR43500"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01324">
        <property type="entry name" value="cysta_beta_ly_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN55986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="395" mass="42762" checksum="EEB3D6F8B0927B11" modified="2016-02-17" version="1">MPPESLPAPRLDWRTKLAHPDAAAPPGFRSLVTPVYRGSTTVFASAAHVHDHWDRRETPYTYGLYGTPTTLELAARIAELEGGGLTFIAPGGQAAIALVDLAVLKAGGHVLIPDCIYGPHREFSDRWLSRWDIRAEYYDPMIGAGIAALLRPQTQLVWCESPGSVTMEVQDVPAIAAAAHAAGVPVALDNTYAAGVFFDAFGHGADIAVQALTKYIGGHSDLLLGSVTVRDEALYRALGDAQQLLGMGVSPDDCSLALRGLQTLGVRLDHLQRSTLEVAQWLQAQPRVARVRHPALPGSPGHEIWKRDFTGSASVFSVEFDAALAQDDLVAFIDRLRLFKIGYSWGGTTSLVVPQFSLHRDLPRAGRNLVRFNIGLERSDDLIEDLRASLARLPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBT4</accession>
    <name>A0A0S2DBT4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0637</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55995">
        <property type="protein sequence ID" value="ALN55995"/>
        <property type="gene ID" value="GLE_0637"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0637"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.626"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="47" mass="5021" checksum="8B3C639FA13E81FE" modified="2016-02-17" version="1">MLIQVKPPADRAGAAPARPPRPPRLCVRSARVRARARRTPPPVTAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBU5</accession>
    <name>A0A0S2DBU5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0633</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55991">
        <property type="protein sequence ID" value="ALN55991"/>
        <property type="gene ID" value="GLE_0633"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0633"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="39" mass="4286" checksum="50CDBA9954D6C232" modified="2016-02-17" version="1">MWEGLQPRRFSIRPQPNRIASEPKASGLKALPQAGGALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBW6</accession>
    <name>A0A0S2DBW6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alcohol dehydrogenase, zinc-containing</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">NAD(P)-dependent alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_04030</name>
        <name evidence="4" type="ORF">GLE_0667</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946200.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0667"/>
    <dbReference type="EnsemblBacteria" id="ALN56025">
        <property type="protein sequence ID" value="ALN56025"/>
        <property type="gene ID" value="GLE_0667"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0667"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.656"/>
    <dbReference type="OMA" id="HCADCDE"/>
    <dbReference type="OrthoDB" id="969875at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="3">
        <location>
            <begin position="11"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW24963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="351" mass="37484" checksum="0A8D0681587B5B49" modified="2016-02-17" version="1">MPKTAAYAAQNAHSPLAPFSIDRRDPGPDEVLIDILYCGVCHSDIHQARDEWGGSIFPMVPGHEIVGRVARAGANVKTFNVGDAVGVGCFVDSCRECAQCKAGEEQYCDQGMTGTYNSTERGSGAPTYGGYSTRITVDQAYVLRIPESIPLDRAAPLLCAGITTYSPLRHYGVKAGDELAVVGLGGLGHMAVKLAVAMGARVTVLSTSESKREAALELGAHAFAATRDKDTLKRLGRSFDFVIDTVSGEHDYNAYLSLLKVDGTMVLLGVPEKPAPVAAGALIMQRRKLGGSLIGGIRETQEMLDFCAEHGVASDIELIGIESINEAYERMIKGDVRYRFVIDIASLENAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC69</accession>
    <name>A0A0S2DC69_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Phosphoribosylamine--glycine ligase</fullName>
            <ecNumber evidence="2 7">6.3.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GARS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glycinamide ribonucleotide synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Phosphoribosylglycinamide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">purD</name>
        <name evidence="11" type="ORF">FE772_04410</name>
        <name evidence="10" type="ORF">GLE_0745</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>5-phospho-beta-D-ribosylamine + ATP + glycine = ADP + H(+) + N(1)-(5-phospho-beta-D-ribosyl)glycinamide + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17453"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:58681"/>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the GARS family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.13" evidence="2 7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946267.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0745"/>
    <dbReference type="EnsemblBacteria" id="ALN56103">
        <property type="protein sequence ID" value="ALN56103"/>
        <property type="gene ID" value="GLE_0745"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0745"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.733"/>
    <dbReference type="OMA" id="KATVCKY"/>
    <dbReference type="OrthoDB" id="932854at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004637">
        <property type="term" value="F:phosphoribosylamine-glycine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00138">
        <property type="entry name" value="GARS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020561">
        <property type="entry name" value="PRibGlycinamid_synth_ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000115">
        <property type="entry name" value="PRibGlycinamide_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020560">
        <property type="entry name" value="PRibGlycinamide_synth_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037123">
        <property type="entry name" value="PRibGlycinamide_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020559">
        <property type="entry name" value="PRibGlycinamide_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020562">
        <property type="entry name" value="PRibGlycinamide_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43472">
        <property type="entry name" value="PTHR43472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01071">
        <property type="entry name" value="GARS_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02843">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02844">
        <property type="entry name" value="GARS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01210">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00877">
        <property type="entry name" value="purD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00184">
        <property type="entry name" value="GARS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="9">
        <location>
            <begin position="109"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN56103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW25027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="431" mass="45286" checksum="638C2B5394A297AF" modified="2016-02-17" version="1">MKVLVIGSGGREHALAWKLAQSPRVDEVLVAPGNAGTAREGKCRNVAVAATDLDGLLKLAADEAVAVTVVGPEAPLVAGVVDRFRAAGRRIFGPTAAAAQLEGSKAFAKDFLARHGIPTAYYAVHTDVDAALAYVREKGAPIVVKADGLAAGKGVIVAMTLPEAEDAVRDMLSGNAFGAAGARVVIEEFLDGEEASFISMVDGEHALPMATSQDHKRVGDGDTGPNTGGMGAYSPAPVVTPAVHDRVMREVVMPTVRGMIADGVPFTGFLYAGLMIDADGAPKVIEFNVRFGDPETQPVMLRLRSDLLDLVEAAIDARLDAVAADWDPRPSLGVVMAAQHYPDTPRTGDPISEWDVPLPVDSHVFHAGTRLVDGQAVTAGGRVLCACALGDSVADAQRRAYEVVAGISWQGEFHRHDIGWRAIERERAAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCF9</accession>
    <name>A0A0S2DCF9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56198">
        <property type="protein sequence ID" value="ALN56198"/>
        <property type="gene ID" value="GLE_0840"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0840"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.829"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="45" mass="5174" checksum="DC50F1B411C1DB94" modified="2016-02-17" version="1">MRGKPRRYARVDRGDAPRTVKNTGNSSRFMRASRFLECDDSGFHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCY6</accession>
    <name>A0A0S2DCY6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1037</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56395">
        <property type="protein sequence ID" value="ALN56395"/>
        <property type="gene ID" value="GLE_1037"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1037"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1025"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="37" mass="3847" checksum="DF1F37331AEE25B7" modified="2016-02-17" version="1">MWGRALVAGPSGPMPFDPARRSGRKASGLKALPQEPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD12</accession>
    <name>A0A0S2DD12_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fumarylacetoacetate hydrolase domain-containing protein 1</fullName>
            <ecNumber evidence="2">3.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1001</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.-.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946454.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1001"/>
    <dbReference type="EnsemblBacteria" id="ALN56359">
        <property type="protein sequence ID" value="ALN56359"/>
        <property type="gene ID" value="GLE_1001"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1001"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.989"/>
    <dbReference type="OMA" id="ESEMVIV"/>
    <dbReference type="OrthoDB" id="775108at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="SSF56529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAA_hydrolase" evidence="1">
        <location>
            <begin position="30"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="242" mass="25574" checksum="FAC3A2BD419B893B" modified="2016-02-17" version="1">MSDVVAAAPATRIPVRGQGLAADAAFPVHRVYCVGRNFADHAREMGAAVPTSTADRGRPTFFLKPTDALDTGEAVPYPPGTTDLHHEVELVVALGRDAPAGVLAVEDAQALVYGYAVGLDLTRRDLQAQAKAKGLPWDTGKSFDHAAPISAIVPAADVGELGARALSLEVNGELRQRGTLDDLVWNVPEILHELSQLYALRAGDLIYMGTPAGVAALQPGDRYRAVLEGVAELHGHITPPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD20</accession>
    <name>A0A0S2DD20_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_05870</name>
        <name evidence="2" type="ORF">GLE_1058</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56416">
        <property type="protein sequence ID" value="ALN56416"/>
        <property type="gene ID" value="GLE_1058"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1058"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1047"/>
    <dbReference type="OMA" id="PARYCEG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="313" mass="33428" checksum="3F94B09017B8C1EC" modified="2016-02-17" version="1">MNPGTRGLLAAAAATAIAVSGWQWWRARGASHTPAAAQAASAPADIAAPTAAAPTAQPARPPDPAQAGYRQRRQDELRQRADAGDSRAACQLGVDLLRCADTSAAQQLLAGAEQNASAGLAPEQRAYMTRMEDRARQLIAECRDARSDAWRQGNRYLRQAALAGEPEAMYRYARGDSVLLDYSHLNTPEFDRWRAEAGNLLQLSFEAGYTPALFDLMTAYSDNSSPITGLIADDPTKARAMRLLVARLSGNPADPPASRDAALEPAAAALAAQWQRDYFAAVKTPLQRMPRVMPASFAALYGEEGGEASACSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD24</accession>
    <name>A0A0S2DD24_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Beta-lactamase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_05960</name>
        <name evidence="3" type="ORF">GLE_1080</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946509.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1080"/>
    <dbReference type="EnsemblBacteria" id="ALN56438">
        <property type="protein sequence ID" value="ALN56438"/>
        <property type="gene ID" value="GLE_1080"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1080"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1067"/>
    <dbReference type="OMA" id="VHPWADV"/>
    <dbReference type="OrthoDB" id="537440at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="90"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="452"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="474" mass="50938" checksum="728FD809426828E3" modified="2016-02-17" version="1">MKRDLSRRSLNPWRLGALAGLLTLTLGSTAQTSLRWQPANPSLPTPVSTDAVARGQGIDGTAPQGLGIGAPANTNLRVQPLAAGFDVQQFEAMAQAMVADQRIPGMAMAIVHNGQILSARGYGITDVRNAEAIDAHTVFRLASLSKSFAGTLTGLLVNDGTLRWDSKVVDYMPGFQMVDANAARTVTVADVLSHRVGLSHNTYDRDLENYADYRVLTQKLAYAPMTCQPGTCYGYQNIAFSLIGDVVFAATGDFYSQEVQRRLFKPLGMNDASLGLEGITASARWAKPHVRARGGWASVTPKPTYYQLPPAAGVNASASDMAQWLIAQTGHRPDVLPLPLLATLHQPLVDTPSEIRGSSWRRQRIGSAGYALGWRVFDYAGHRVVFHAGAVQGYRGMVAMVPERDLGIAVLWNSESGLPTGMLPTILDRAIGMPVQRWLDVDGFDDPGLYASEGVGPARDVNGSNAQKSTAAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDF2</accession>
    <name>A0A0S2DDF2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Siroheme synthase</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="14">Uroporphyrinogen-III C-methyltransferase</fullName>
                <shortName evidence="14">Urogen III methylase</shortName>
                <ecNumber evidence="14">2.1.1.107</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="14">SUMT</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="14">Uroporphyrinogen III methylase</fullName>
                <shortName evidence="14">UROM</shortName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="14">Precorrin-2 dehydrogenase</fullName>
                <ecNumber evidence="14">1.3.1.76</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="14">Sirohydrochlorin ferrochelatase</fullName>
                <ecNumber evidence="14">4.99.1.4</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="21" type="primary">cobA</name>
        <name evidence="14" type="synonym">cysG</name>
        <name evidence="21" type="ORF">GLE_1230</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>2 H(+) + siroheme = Fe(2+) + sirohydrochlorin</text>
            <dbReference type="Rhea" id="RHEA:24360"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:58351"/>
            <dbReference type="ChEBI" id="CHEBI:60052"/>
            <dbReference type="EC" id="4.99.1.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>2 S-adenosyl-L-methionine + uroporphyrinogen III = H(+) + precorrin-2 + 2 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:32459"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58827"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.1.1.107"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>NAD(+) + precorrin-2 = 2 H(+) + NADH + sirohydrochlorin</text>
            <dbReference type="Rhea" id="RHEA:15613"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58351"/>
            <dbReference type="ChEBI" id="CHEBI:58827"/>
            <dbReference type="EC" id="1.3.1.76"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="14">Cofactor biosynthesis; adenosylcobalamin biosynthesis; precorrin-2 from uroporphyrinogen III: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="14">Cofactor biosynthesis; adenosylcobalamin biosynthesis; sirohydrochlorin from precorrin-2: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="13 14">Porphyrin-containing compound metabolism; siroheme biosynthesis; precorrin-2 from uroporphyrinogen III: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="14">Porphyrin-containing compound metabolism; siroheme biosynthesis; siroheme from sirohydrochlorin: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Porphyrin-containing compound metabolism; siroheme biosynthesis; sirohydrochlorin from precorrin-2: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 16">Belongs to the precorrin methyltransferase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">In the C-terminal section; belongs to the precorrin methyltransferase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.107" evidence="14"/>
    <dbReference type="EC" id="1.3.1.76" evidence="14"/>
    <dbReference type="EC" id="4.99.1.4" evidence="14"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1230"/>
    <dbReference type="EnsemblBacteria" id="ALN56587">
        <property type="protein sequence ID" value="ALN56587"/>
        <property type="gene ID" value="GLE_1230"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1230"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1215"/>
    <dbReference type="OMA" id="DATSHIH"/>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00211"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00262">
        <property type="reaction ID" value="UER00211"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043115">
        <property type="term" value="F:precorrin-2 dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051266">
        <property type="term" value="F:sirohydrochlorin ferrochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004851">
        <property type="term" value="F:uroporphyrin-III C-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019354">
        <property type="term" value="P:siroheme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11642">
        <property type="entry name" value="SUMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01646">
        <property type="entry name" value="Siroheme_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006366">
        <property type="entry name" value="CobA/CysG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037115">
        <property type="entry name" value="Sirohaem_synt_dimer_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012409">
        <property type="entry name" value="Sirohaem_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028281">
        <property type="entry name" value="Sirohaem_synthase_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019478">
        <property type="entry name" value="Sirohaem_synthase_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006367">
        <property type="entry name" value="Sirohaem_synthase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003043">
        <property type="entry name" value="Uropor_MeTrfase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10414">
        <property type="entry name" value="CysG_dimeriser"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14824">
        <property type="entry name" value="Sirohm_synth_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036426">
        <property type="entry name" value="Sirohaem_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01469">
        <property type="entry name" value="cobA_cysG_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01470">
        <property type="entry name" value="cysG_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00839">
        <property type="entry name" value="SUMT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00840">
        <property type="entry name" value="SUMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 14" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="10 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 14 16" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12 14" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="9 14" id="KW-0520">NAD</keyword>
    <keyword evidence="8 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11 14" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 14 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sirohm_synth_M" evidence="20">
        <location>
            <begin position="140"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="CysG_dimeriser" evidence="19">
        <location>
            <begin position="171"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="TP_methylase" evidence="18">
        <location>
            <begin position="241"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase" evidence="14">
        <location>
            <begin position="1"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Uroporphyrinogen-III C-methyltransferase" evidence="14">
        <location>
            <begin position="239"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="14">
        <location>
            <begin position="324"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="14">
        <location>
            <begin position="354"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="14 15">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="14 15">
        <location>
            <position position="293"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="43"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="64"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="406"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="435"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="Phosphoserine" evidence="14">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01646"/>
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    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR036426-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU003960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF10414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF14824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ALN56587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="498" mass="52815" checksum="FB0466EDDCAC2583" modified="2016-02-17" version="1">MTRASSRSEHDNAPQAGERPGGGLFPLFADLRGRGVLVVGGGAVAQRKTAALLDAGATVRVGAPTLNPGLSAWAAEGRIEHLPGEFAPQWLDEAWLAIAATDDAAVNRAVAAAGEARRIWVNVVDDVEASGFHVPARVERGPVQIAISSGGGAPMLARHLREKLETELDESLGALAQLLNRERARIRRHYPDLGQRRRFFERVLAGAIPALLRDGRHDEAQRAFGAALIDDKPAAPPAGSVVLVGAGPGDAGLMTLRGLRALNQADVILHDRLVSRDVLRLARRDAELIEVGKQAGNHHTTQERIHELMLEHARAGKRVVRLKGGDPFVFGRGGEELEVLAQAGIGFEVVPGITAALACAAYAGVPLTHRDHAQSLRLVTAHLKDSAGDLDWQALAQDKQTLAVYMGVAGLDVLRDKLIEHGRAASTPFALIENGSRPGQRVVTGTLADLAERAQGHRVQSPALLIVGEVAALAQRLHWFGPAPLTEPPADAALARAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDJ1</accession>
    <name>A0A0S2DDJ1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56622">
        <property type="protein sequence ID" value="ALN56622"/>
        <property type="gene ID" value="GLE_1265"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1265"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1249"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="69" mass="7432" checksum="EB57A51255E6A024" modified="2016-02-17" version="1">MAHGALPGTAWTVAGEPSRARIAANGTATARRLAARRLCANWRKSWQPSAFAAHRSRWDRSSGSRMAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDR9</accession>
    <name>A0A0S2DDR9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLE_1406</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946752.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1406"/>
    <dbReference type="EnsemblBacteria" id="ALN56763">
        <property type="protein sequence ID" value="ALN56763"/>
        <property type="gene ID" value="GLE_1406"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1406"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1386"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595028" evidence="6">
        <location>
            <begin position="40"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="80"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="7">
        <location>
            <begin position="335"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="818" mass="88137" checksum="357FA0568869EEB8" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDS0</accession>
    <name>A0A0S2DDS0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Rhs element Vgr protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1322</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1322"/>
    <dbReference type="EnsemblBacteria" id="ALN56679">
        <property type="protein sequence ID" value="ALN56679"/>
        <property type="gene ID" value="GLE_1322"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1322"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1306"/>
    <dbReference type="OMA" id="ARERDGC"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008727">
        <property type="entry name" value="PAAR_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05488">
        <property type="entry name" value="PAAR_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="444" mass="47866" checksum="7EB687B053297F41" modified="2016-02-17" version="1">MGDTTSSGGQVVSGSPFTDIDGKPVARIGDSVVCGLHGPTVIASGDATFIVDGQPLARERDGCACGCLLVSVRQMSTSVAAGGAGGGGMAGGGEVFAAAAAASPEFATDTRLGDDAGRFDEQLRFSSAGGLPLALTRYAITLGDGQVLQGTTDEDGKTARIVTDRPQAVIQAKFFPPDRTRTCCAQHVGASTPSATTVAIAGVQTNAVALGASQAQVTLEGESRGLTEGEKRLARRIFKDAIDYDKVKIHNDEYLWFGMQDDNTAMTPNGEMWMPKNLFREDYSVEDDSMKHLFVHEMVHVWQYQLGYNVKANGLKIHGLYESDKLDHRTGLLKKRPVSPYEYSLAPRRELPLFQKPKYVLKDAGYVEVFSSLSDFNMEQQGDIIADYASHKRYLGPTQPMSESGLKIPQAQRGRWLEAVLAGFLAMPSSRSLVPTTTKRADER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDX0</accession>
    <name>A0A0S2DDX0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histidine phosphatase family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Phosphoglycerate mutase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_07115</name>
        <name evidence="1" type="ORF">GLE_1333</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946695.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1333"/>
    <dbReference type="EnsemblBacteria" id="ALN56690">
        <property type="protein sequence ID" value="ALN56690"/>
        <property type="gene ID" value="GLE_1333"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1333"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1315"/>
    <dbReference type="OMA" id="TRHGKTE"/>
    <dbReference type="OrthoDB" id="1122642at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="214" mass="23781" checksum="9BB170F89FE64BB5" modified="2016-02-17" version="1">MRILLARHGETPWNAEGRYQGQEDIALSPVGETQARALGARLREVPVTRAVASPLSRARRTAELALGEERAPMLKLDPGLMEIAHGTWEGLLASEIRERDGDRLRAWRETPHEVLMPGGESIVHVLDRAWPAFAKACEGLKDDDTLLVVAHDAVNRVLLCRILGIPLAKLWTFRQAPTTLNLLEGDHVDRLEVVRLNDCSHHTALFGEAVHRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDX5</accession>
    <name>A0A0S2DDX5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative pre-16S rRNA nuclease</fullName>
            <ecNumber evidence="2">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BV903_16325</name>
        <name evidence="4" type="ORF">GLE_1178</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">B25</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YqgF HJR family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000043">
        <property type="protein sequence ID" value="OPD62845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946573.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1178"/>
    <dbReference type="EnsemblBacteria" id="ALN56536">
        <property type="protein sequence ID" value="ALN56536"/>
        <property type="gene ID" value="GLE_1178"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62845">
        <property type="protein sequence ID" value="OPD62845"/>
        <property type="gene ID" value="BV903_16325"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1178"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1163"/>
    <dbReference type="OMA" id="PMGWTAQ"/>
    <dbReference type="OrthoDB" id="2075502at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000967">
        <property type="term" value="P:rRNA 5'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16964">
        <property type="entry name" value="YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00651">
        <property type="entry name" value="Nuclease_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005227">
        <property type="entry name" value="YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006641">
        <property type="entry name" value="YqgF/RNaseH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33317">
        <property type="entry name" value="PTHR33317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03652">
        <property type="entry name" value="RuvX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00732">
        <property type="entry name" value="YqgFc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00250">
        <property type="entry name" value="RNAse_H_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="YqgFc" evidence="3">
        <location>
            <begin position="13"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD62845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="162" mass="17443" checksum="2A2A99B146B2F334" modified="2016-02-17" version="1">MSAGASDEIRRDGTVLGFDVGSRRIGVAVASAFGHGARALAVIDVHGASPDWGAIDRLQKEWRPDGLIVGDPMTLDGGDQPARQRALAFARQLRVRYKLPVVLVDERSSSVEAAHRFAADRAEGRKRRRDAEALDAVAAAVIVERWLAAPDDATDIDQVPHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE62</accession>
    <name>A0A0S2DE62_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA polymerase sigma factor, sigma-70 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">RNA polymerase subunit sigma-70</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Sigma-70 family RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BV903_19340</name>
        <name evidence="7" type="ORF">FE772_07380</name>
        <name evidence="5" type="ORF">GLE_1393</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
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            <end position="84"/>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        <source>
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    <evidence type="ECO:0000313" key="9">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="169" mass="19243" checksum="4CD315255FBE3209" modified="2016-02-17" version="1">MRGEATAARQRRFEALLAAHRGIVYKVAAGYARGEDERADLAQDIAAQLWRAFPRYDPQRSFSTWMYRIALNVAISHLRERSRRHDTLALDEDLHALPADDGDTPEIAQRLRLLQRLIAQQPPLDRALLLLYLEDRGHREIAEVLGLSESNVATKIGRLKQRLRAALAD</sequence>
</entry>
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    <accession>A0A0S2DE72</accession>
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        <submittedName>
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        </submittedName>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
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        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
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        <property type="gene ID" value="GLE_1444"/>
    </dbReference>
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    <dbReference type="PATRIC" id="fig|69.6.peg.1424"/>
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    <dbReference type="OrthoDB" id="781228at2"/>
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    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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            <end position="71"/>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="OPD63479.1"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="441" mass="45890" checksum="A03A1959CE572DAB" modified="2016-02-17" version="1">MTALFSAWFRIPFWQRVVAGFALGALAGWAMGPAAETWFGPLGDLYVTLIKMIAVPLVFFAVINAVASLHGQKSIAALGGRTFLWFAITAVLAVAVGLAVGTILQPGSGVIGLAASSDYKPRDVPSVTKVLLDVVPSNPFYALTGIGATKNAAGETVLAAGKGSILPVIFFAGLLGFAMVKLGEKVAGVRKLVGEASELMIQVTRFVLEVTPIGTFGLIAALVGAYGFEKLLPLGNFVLALYLACALHIVVVYSALLLAHGLNPLKFFRGAAPGMQVAFVSSSSFAAMPVAMRSIVHNLGVNKDYAAFASPLGASIKMDGCGAIYPALCAVFIAQYTGTPLTADQYFIVLIASVLGSFGTAGVPGTAVIMATVVLSAANLPLETIGYLYAIDRVLDMMRTMTNVTGQMLVPVLVAKETGLLDREVYEAASSNVGIEEEAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEC0</accession>
    <name>A0A0S2DEC0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TrbL/VirB6 plasmid conjugal transfer protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Type IV secretion system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_08080</name>
        <name evidence="7" type="ORF">GLE_1543</name>
    </gene>
    <organism evidence="7 9">
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        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56900.1"/>
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    </dbReference>
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        <property type="protein sequence ID" value="QCW25631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946864.1">
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_1543"/>
    <dbReference type="EnsemblBacteria" id="ALN56900">
        <property type="protein sequence ID" value="ALN56900"/>
        <property type="gene ID" value="GLE_1543"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1543"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1525"/>
    <dbReference type="OrthoDB" id="1488773at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030255">
        <property type="term" value="P:protein secretion by the type IV secretion system"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Conjugal_tfr_TrbL/VirB6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04610">
        <property type="entry name" value="TrbL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
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            <end position="75"/>
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            <end position="117"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="190"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="321"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="341"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="371"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN56900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW25631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="397" mass="42535" checksum="A0E833B06ADEED5B" modified="2016-02-17" version="1">MLDQSTAALSLLPDLLRGPSAQFESLGQWVFFKIVFEFLDHEILAFRETMVHGMANWVGALATTLMALWIFMQGYKVMTGQSRNSMMELAVGSMRNVLIVMVATSLTVGTSSLYATLTDDLPRAIAESVTGRDQDPAQTIDRGLTNMQLAMAAIEALPALDNPGIKDDKDRALMLTGIGVAGPAVVGGALLVMYKFALALFVGLGPLFILALMFDQTKSMFARWLQYGIGTMFSLAVLSFTVTVAMKMVGAVAANFAAQYMTMMALGAGDSPGVNTMALQQGGLGIFLTVLILSVPPMASSFFQGVLGNFMHYSAFGANSAPGKPETSGHGGYKPENSARSAEQARASQNQHTNQSTQNTSLGSGKLTSNHNDTHAKDTLKDTGSQKDEIRKHDNHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEE1</accession>
    <name>A0A0S2DEE1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1328</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56685">
        <property type="protein sequence ID" value="ALN56685"/>
        <property type="gene ID" value="GLE_1328"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1328"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="58" mass="6139" checksum="B3BDA8048043214D" modified="2016-02-17" version="1">MVERNEASAWGQCVARLPRSRGGGRGGGMRNDENKNGGVAPAVAFVVCVRRGQIPQSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEE3</accession>
    <name>A0A0S2DEE3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein phosphatase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Protein phosphatase 2C</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Serine/threonine-protein phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_07120</name>
        <name evidence="5" type="ORF">D9T17_19060</name>
        <name evidence="4" type="ORF">FE772_08610</name>
        <name evidence="2" type="ORF">GLE_1662</name>
    </gene>
    <organism evidence="2 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">C3</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 9" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000013">
        <property type="protein sequence ID" value="OPD64655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000046">
        <property type="protein sequence ID" value="ROU05388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946956.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000046.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1662"/>
    <dbReference type="EnsemblBacteria" id="ALN57019">
        <property type="protein sequence ID" value="ALN57019"/>
        <property type="gene ID" value="GLE_1662"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64655">
        <property type="protein sequence ID" value="OPD64655"/>
        <property type="gene ID" value="BV903_07120"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1662"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1641"/>
    <dbReference type="OMA" id="EDHTWVA"/>
    <dbReference type="OrthoDB" id="1835483at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PTHR13832"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU05388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="234" mass="25602" checksum="B5908AD165263692" modified="2016-02-17" version="1">MIEFGHLTHVGLRRELNEDTYYGDSELGLWLVADGMGGHEYGEVASALAREVIVREVRGGSALAQAIRIADEEIIRTSRRRNDTLPMGTTVVAARINGNRFEVAWVGDSRVYLWRDGHLAQLSQDHSYVQELIANGVITHEQARSHPHRSVVTQALGVTDPRNLNVETMTGELRPGMQLLLCSDGLTEEVDDRAIARVLAHNDCSAQECVDSLVAAALDGGGSDNITVVLVRSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEM9</accession>
    <name>A0A0S2DEM9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DMT family transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Integral membrane protein DUF6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_07455</name>
        <name evidence="4" type="ORF">GLE_1410</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946756.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56767">
        <property type="protein sequence ID" value="ALN56767"/>
        <property type="gene ID" value="GLE_1410"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1410"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1390"/>
    <dbReference type="OMA" id="TSPLWGM"/>
    <dbReference type="OrthoDB" id="1425840at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="265"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="288"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="3">
        <location>
            <begin position="40"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="3">
        <location>
            <begin position="174"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="311" mass="32053" checksum="E09E4B7330FD07CB" modified="2016-02-17" version="1">MRSPELAATVTPNGSAPAPVAATDSARAGWRTPLELTVLGAIWGGSFLFMRVAAKDFGALPLVEMRLGLGALILLPFLWKARESFRGAKIWAKLALIGVINSALPFALFAWAAQRAPAGVGAITNSMAVLFTALVGFLFFGEKIGAQRAIALLAGFAGVVVLASGKTAGASIGWAVAAGCAAAFLYGIGANLVRRQLTGLPAAAVAAATLGSSALLTLPFAIASWPTHAIPAKSWLSASMLGVLCTGIAFVMYYRLIQRIGAGRAVAVTYLVPLFGVAWGWMLLDEPLTLSMLIAGALILGSVAMSQRAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEP0</accession>
    <name>A0A0S2DEP0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator receiver/LytTr DNA-binding domain protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_08055</name>
        <name evidence="4" type="ORF">GLE_1539</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946861.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1539"/>
    <dbReference type="EnsemblBacteria" id="ALN56896">
        <property type="protein sequence ID" value="ALN56896"/>
        <property type="gene ID" value="GLE_1539"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1539"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1521"/>
    <dbReference type="OMA" id="VARQYAH"/>
    <dbReference type="OrthoDB" id="1958442at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="15"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="166"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="268" mass="29630" checksum="E85EFBC022014F27" modified="2016-02-17" version="1">MSEPHTAEHPTGAPTALIAEDETLLRQALVEALREAWPELRILAECEDGAQALEALAEHRPDVAFLDIRMPGLTGLDLAAAATDVSPATQIVFVTAYDQHAIDAFEHGAVDYLLKPVTVDRLAVTVRRLRVRRAPGDDRHAALREIARELAARRPTQDDKPALTWITASAGRETRLILVDDVVYFRADNKYTTVVTAEGEALLRTPIRDLLDRLDGERFKQIHRSTIVNLKAIAGIVRDDSGKGTVRLRGRPETLSVSQTFMALFKSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEP1</accession>
    <name>A0A0S2DEP1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FE772_07525</name>
        <name evidence="9" type="ORF">GLE_1426</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946766.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1426"/>
    <dbReference type="EnsemblBacteria" id="ALN56783">
        <property type="protein sequence ID" value="ALN56783"/>
        <property type="gene ID" value="GLE_1426"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1426"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1406"/>
    <dbReference type="OMA" id="CRFSTRE"/>
    <dbReference type="OrthoDB" id="71288at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010917">
        <property type="entry name" value="TonB_rcpt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01156">
        <property type="entry name" value="TONB_DEPENDENT_REC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242151" evidence="6">
        <location>
            <begin position="31"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="65"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="7">
        <location>
            <begin position="404"/>
            <end position="881"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW25534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="882" mass="95443" checksum="0E62A5E9022DAA43" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFE3</accession>
    <name>A0A0S2DFE3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methanol dehydrogenase regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1683</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1683"/>
    <dbReference type="EnsemblBacteria" id="ALN57039">
        <property type="protein sequence ID" value="ALN57039"/>
        <property type="gene ID" value="GLE_1683"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1683"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1661"/>
    <dbReference type="OMA" id="NRFQMND"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_3" evidence="1">
        <location>
            <begin position="84"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_lid_2" evidence="2">
        <location>
            <begin position="277"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="350" mass="37419" checksum="9692DCCE2970604A" modified="2016-02-17" version="1">MRRVADPHEPDKNDIFDFTRLYHTTAGPMSAGKITASSATHDAAILTDGLRSALEQAQAQVNALVLGKAQAVRLAFVALLSDGHLLIEDLPGLGKTTLAHALAATLGLEFQRVQFTSDLLPADVVGVSVFDPTSRQFQFHPGPVFAQVLLADEINRAPPRTQSALLEAMAEHQVTVDGRSHRLPDPFFVIATQNPVDLSGTYPLPDSQLDRFLLRLQLGYPDEAAERDLLAGADRRHLIAQARALLSAPDVQAIRSAVDAVHASEALIGYVQALLARSRKHPGVRVGLSPRAGLALLRAARAYALLLGRGHVVPEDVQALFAAVATHRLVAEADAAADLAKSILYAVAVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFT1</accession>
    <name>A0A0S2DFT1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sensor protein</fullName>
            <ecNumber evidence="5">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_1781</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Member of a two-component regulatory system.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="GLE_1781"/>
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    <dbReference type="KEGG" id="lez:GLE_1781"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1755"/>
    <dbReference type="OMA" id="RSAEHYF"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:phosphorelay sensor kinase activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="CztS_silS_copS"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
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        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
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        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF00672">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="cztS_silS_copS"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="13"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="162"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="7">
        <location>
            <begin position="186"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="247"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN57135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="467" mass="50938" checksum="00991BC3516BED74" modified="2016-02-17" version="1">MTPWRELPIARRLAAMFAGAALLVFALVGIALYQVLQTQIVRYQHAELETKLRYVAGSVNACELRERWHKVEDKVDSLVSSDRSTKVWAWSDSALFRIGAGAPPVEAARGAADRGMGRLWLADSDAPYRVLAQTIPAKGERPPVRIWVAIDSQPYRAALRSFAFALVALGLGGAALVALLGHWIAQVGLRPLQRLSSDAQRLSPSNLSQRLQPTDLPPELGRVAGAFNGALDRLEAAYTRLEAFNADVAHELRTPLTNLMGQTQVALQRPREAQRLTEVLTSNLEELERMRGIVNDMLFLSRAGQGDIALDRVCVPLAAEVAKTGEFLEYLLEEAGMRLRIDGAADAWIDTSLFRRAMTNLLHNAVQHATPGSEIVVEVRCGEAVPGDCGSGASVAVRNEGKCVEPQHLARMFDRFYRVDEAREHRGERHHGLGLSIVKAIASLHGGNVFANSGEGRTTVGFSLAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFU1</accession>
    <name>A0A0S2DFU1_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">DUF333 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_10290</name>
        <name evidence="2" type="ORF">GLE_2028</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57378">
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        <property type="gene ID" value="GLE_2028"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242194" evidence="1">
        <location>
            <begin position="19"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="97" mass="10136" checksum="BBB8103346046093" modified="2016-02-17" version="1">MSLRAASVLLPLALLALAACSTPSEPVATKSDPMPAAEAKGVGMANPASVNCQKLGGRLEIRTGKDGGQYGLCHLPDGRVCEEWALMRDNKCEKPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFV2</accession>
    <name>A0A0S2DFV2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Microcystin dependent protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Phage tail protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_10710</name>
        <name evidence="4" type="ORF">FE772_10545</name>
        <name evidence="2" type="ORF">GLE_2084</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000024">
        <property type="protein sequence ID" value="OPD63954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947265.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2084"/>
    <dbReference type="EnsemblBacteria" id="ALN57434">
        <property type="protein sequence ID" value="ALN57434"/>
        <property type="gene ID" value="GLE_2084"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63954">
        <property type="protein sequence ID" value="OPD63954"/>
        <property type="gene ID" value="BV903_10710"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2084"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2049"/>
    <dbReference type="OMA" id="NFQPYLC"/>
    <dbReference type="OrthoDB" id="1837650at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011083">
        <property type="entry name" value="Phage_tail_collar_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037053">
        <property type="entry name" value="Phage_tail_collar_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07484">
        <property type="entry name" value="Collar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Collar" evidence="1">
        <location>
            <begin position="7"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="176" mass="18506" checksum="870643C5EDE9E5A1" modified="2016-02-17" version="1">MSEPYLGEIRLFGFTRVPQGWYACNGQMVSIAENEALFMLLGTIYGGDGITTFAVPDMQGRVPVHFGTSPGLSTYVIGQRAGSESITLIGQQMPQHTHTMVATTLTATAKTPAANLELGALNGDVLYVTDTSGASAFPASPLSVSAVGGNQPHENQMPTLTVQYCIAAYGVFPSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGD0</accession>
    <name>A0A0S2DGD0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nucleotidyltransferase/DNA polymerase involved in DNA repair</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_2205</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA polymerase type-Y family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947362.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2205"/>
    <dbReference type="EnsemblBacteria" id="ALN57554">
        <property type="protein sequence ID" value="ALN57554"/>
        <property type="gene ID" value="GLE_2205"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2205"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2167"/>
    <dbReference type="OMA" id="HRPECAW"/>
    <dbReference type="OrthoDB" id="658705at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="UmuC" evidence="3">
        <location>
            <begin position="23"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="398"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="485" mass="53762" checksum="0C8D3B58B6D3C447" modified="2016-02-17" version="1">MRWACLLLPQLAMDVVLRQHPNPDQPLALVEGPHARRRLHSVNAAARALGLRPGLSLVAAHAIADGVRTAEYDPQAAERARQLLAAWAYRYSSQVSTDFAHALVLEIAGSRRLFGAWPQLRQRLDAELRELGFRHRMAAAPNPFAARALTNIGEGLFFDDDLLLPALAKMPIERSGLDPATVQALQRMGLRKLGAVFALPRAPLARRFGPDLLQRLDALRGAAEPPLTFYQPPDAFDARIELGHEAESSQALLFPLRRLTADLAAYLSGRDGGVARFKLLLEHERHSHRLQHPPSEIAVGLLAPEREAAMLFELARGRLQHAQLPAPVVALRLLAEELPPFVPAARDLFDPRPQQALPWAQLRERLRARLGDERVHGLAAHPDHRPERAWQPVLGDAPAARGKHAATPAPTLPATRPGWLLAEPEPLREPVARILAGPERIESGWWDQDDVRRDYYLVETARGQRAWAYRDAGGDGPLIVHGWFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGM8</accession>
    <name>A0A0S2DGM8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter, permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_2341</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2341"/>
    <dbReference type="EnsemblBacteria" id="ALN57690">
        <property type="protein sequence ID" value="ALN57690"/>
        <property type="gene ID" value="GLE_2341"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2341"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2303"/>
    <dbReference type="OMA" id="YPIAYGM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="279"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="94"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="319" mass="35257" checksum="294172E6D6977271" modified="2016-02-17" version="1">MVYNLFGWFRAVGDEFRTRRGRFLVTAIPMLWLALFFCVPFLIVLKISFAQSVFGQVPPYTPLLETAENGATTLRLHAANYAALLADPLYVAAYLKSLLFAGVSTLCCLLLGYPIAYGIARAPRLWRLLLLVLVILPFWTSSLLRTYALIGLLRANGWLSQTLAGLGVLEPGQAVLHTNLAVYIGITYNYLPFMILPLAATLIRLDFTLLEAAADLGAKPWQAFRRVTLPLSFPGILAGSLLVFIPAVGEFVIPDVLGGPDALTIGRVLWTEFFTNRDWPLSAAIAVAMLLLIVLPTLLFEYIENRVDKGRRVAREAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGR9</accession>
    <name>A0A0S2DGR9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_11335</name>
        <name evidence="3" type="ORF">GLE_2249</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947399.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57598">
        <property type="protein sequence ID" value="ALN57598"/>
        <property type="gene ID" value="GLE_2249"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2249"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2214"/>
    <dbReference type="OrthoDB" id="1946033at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726557" evidence="2">
        <location>
            <begin position="26"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="271" mass="30515" checksum="87CD2E1E8249AB7B" modified="2016-02-17" version="1">MNLRILPAALLSLALAFAFALPMQAQVQAQTRDFKLYNNTKYTDGDDRRLDIARSNLLGEPQLPELAKGVMPDEKRYKDAVRASLGNPGPLVLDFEHINLAKDPQLSATNLDKLQTLARWAREAAPGRQIGYYGFPGSIDKNDPARGKQLAESVDLFFPSLYTVDDDRDRWRRRLDNMVAAARKLDASKPVLPFVWPQYHDKTPRDGEFVASDYWKFQLDQLHRAADGAVIWSKRVSGGERDWVPVTRSFIQSAKPASSPSQPSRRAAPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH28</accession>
    <name>A0A0S2DH28_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type VI secretion system FHA domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2583</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2583"/>
    <dbReference type="EnsemblBacteria" id="ALN57932">
        <property type="protein sequence ID" value="ALN57932"/>
        <property type="gene ID" value="GLE_2583"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2583"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2542"/>
    <dbReference type="OMA" id="EAEDDFH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017735">
        <property type="entry name" value="T6SS_FHA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03354">
        <property type="entry name" value="VI_FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="30"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="528" mass="55716" checksum="C4F1C9E20DA8D203" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH31</accession>
    <name>A0A0S2DH31_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2345</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947467.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2345"/>
    <dbReference type="EnsemblBacteria" id="ALN57694">
        <property type="protein sequence ID" value="ALN57694"/>
        <property type="gene ID" value="GLE_2345"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2345"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2307"/>
    <dbReference type="OMA" id="VVCMMRA"/>
    <dbReference type="OrthoDB" id="1591366at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08417">
        <property type="entry name" value="PBP2_Nitroaromatics_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037402">
        <property type="entry name" value="YidZ_PBP2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="11"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="308" mass="34096" checksum="E0ED0424A616E1F5" modified="2016-02-17" version="1">MNQIHTRSEQLDLNLLKVFEAVYRERNLSLAAQALYLTPSAVSHALARLRRQFDDPLFVRDGRRMSPTAACQRLAPPLLETLARLRELLQHRDRFEPGSSRQSFRIGMPEATETVLLPALMRALRAQAPGATLASVALPRRDLGRELAAGQVDLAVDVALPVRDPVRHRPLFEDGFCVVARADHPLARRMSLKQYLQARHVAVSARATGQVIEDLALLHLGLQRDIALRCRSYHAACAVAAQSDALLTLPESLAARIAPDGALARLKLPFALPAAQLHLYWHANSEADPANAWLRGLVSEVCGRKLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHU9</accession>
    <name>A0A0S2DHU9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2720"/>
    <dbReference type="EnsemblBacteria" id="ALN58068">
        <property type="protein sequence ID" value="ALN58068"/>
        <property type="gene ID" value="GLE_2720"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2720"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2679"/>
    <dbReference type="OMA" id="YSWQLAP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004343">
        <property type="term" value="F:glucosamine 6-phosphate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039143">
        <property type="entry name" value="GNPNAT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355">
        <property type="entry name" value="PTHR13355"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="13"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="306" mass="33545" checksum="3E4004B82F243DA1" modified="2016-02-17" version="1">MSAPAPALGFRVIAVEDYAAAQPALRAVREAVFVREQNVPLALELDAERDPQCQHVLAFDESGEPIGTGRLTPDRRIGRMAVLGAWRGRGVGEALLAALLERAQTLGWREVSLHSQASATGFYARHGFLPFGERFVEAGIEHVAMYRLLGAPNPVDGREAALAALTGILAQARRGLWICSRELDPGLLDRAEAVAALRRFAVGGGQVRVLLHDPAAPQRALAPLIGLAQRLPTAFEFRAIEETVDQNDPAAYLVNDRDGWYYRPLGHRFDGETRIDGGPRARQLRARFEPVWERARPCTELRALGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHX9</accession>
    <name>A0A0S2DHX9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methylthioribose-1-phosphate isomerase</fullName>
            <shortName evidence="3">M1Pi</shortName>
            <shortName evidence="3">MTR-1-P isomerase</shortName>
            <ecNumber evidence="3">5.3.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">S-methyl-5-thioribose-1-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 4" type="primary">mtnA</name>
        <name evidence="5" type="ORF">FE772_13750</name>
        <name evidence="4" type="ORF">GLE_2752</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>S-methyl-5-thio-alpha-D-ribose 1-phosphate = S-methyl-5-thio-D-ribulose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:19989"/>
            <dbReference type="ChEBI" id="CHEBI:58533"/>
            <dbReference type="ChEBI" id="CHEBI:58548"/>
            <dbReference type="EC" id="5.3.1.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 1/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.23" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947785.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2752"/>
    <dbReference type="EnsemblBacteria" id="ALN58100">
        <property type="protein sequence ID" value="ALN58100"/>
        <property type="gene ID" value="GLE_2752"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2752"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2709"/>
    <dbReference type="OMA" id="RLWVDET"/>
    <dbReference type="OrthoDB" id="1290468at2"/>
    <dbReference type="UniPathway" id="UPA00904">
        <property type="reaction ID" value="UER00874"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046523">
        <property type="term" value="F:S-methyl-5-thioribose-1-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019284">
        <property type="term" value="P:L-methionine salvage from S-adenosylmethionine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01678">
        <property type="entry name" value="Salvage_MtnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005251">
        <property type="entry name" value="IF-M1Pi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011559">
        <property type="entry name" value="Initiation_fac_2B_a/b/d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027363">
        <property type="entry name" value="M1Pi_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00524">
        <property type="entry name" value="eIF-2B_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00512">
        <property type="entry name" value="salvage_mtnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1 3" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="56"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="253"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="243"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="3">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="353" mass="37248" checksum="BFAA3D3DBDE609BD" modified="2016-02-17" version="1">MNDAIDFDRYDRIRPIRWTGQALELLDQRKLPFAVEYVSCADSDEVAAAIHALTVRGAPAIGIAAAWGAVLAARAVEAADGAQALAAIEPALQRLNAARPTAVNLAWALARMRRALDGAGADWREVLEREAQAIAEEDLAANRRMGALGAALIEPGRGVLTHCNTGSLATAGFGTALGVIRAGVAQGRIERVFAGETRPWLQGARLTVWELEQDGIAPTLIADSAASHLMKSGQVGWVIVGADRICANGDTANKIGTYQLAIAARHHGVKFMVVAPSSTVDMATASGELIEIEERDPAELFAVGGARTAAERVGAWNPVFDVTPHELINAIVTERGVIERPDAAAMREAFSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIH4</accession>
    <name>A0A0S2DIH4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3096</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948038.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3096"/>
    <dbReference type="EnsemblBacteria" id="ALN58443">
        <property type="protein sequence ID" value="ALN58443"/>
        <property type="gene ID" value="GLE_3096"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3096"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3054"/>
    <dbReference type="OrthoDB" id="1542724at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="SSF51695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="122" mass="12942" checksum="D8D677E6959FDDAF" modified="2016-02-17" version="1">MQAHYASGLGPYKASLIERAPLPAKRDADGDGHALLATRNTGIVHPVLARALALGLQVHPYTVRAEEPFLTQTANGIDQSALGEALQLYGLGVQGFFIDNPDIGVAARNLFLEQSKIAPIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJA7</accession>
    <name>A0A0S2DJA7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">DNA repair protein RadA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">radA</name>
        <name evidence="9" type="ORF">BV903_21045</name>
        <name evidence="10" type="ORF">FE772_16205</name>
        <name evidence="8" type="ORF">GLE_3274</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.</text>
    </comment>
    <comment type="function">
        <text evidence="5">Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.</text>
    </comment>
    <comment type="domain">
        <text evidence="5">The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the RecA family. RadA subfamily.</text>
    </comment>
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        <property type="protein sequence ID" value="ALN58620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD61968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW26949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_MTAY01000066.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3274"/>
    <dbReference type="EnsemblBacteria" id="ALN58620">
        <property type="protein sequence ID" value="ALN58620"/>
        <property type="gene ID" value="GLE_3274"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61968">
        <property type="protein sequence ID" value="OPD61968"/>
        <property type="gene ID" value="BV903_21045"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3274"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3227"/>
    <dbReference type="OMA" id="FELMRLA"/>
    <dbReference type="OrthoDB" id="505485at2"/>
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        <property type="component" value="Chromosome"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000725">
        <property type="term" value="P:recombinational repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01121">
        <property type="entry name" value="Sms"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01498">
        <property type="entry name" value="RadA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004504">
        <property type="entry name" value="DNA_repair_RadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014774">
        <property type="entry name" value="KaiC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041166">
        <property type="entry name" value="Rubredoxin_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06745">
        <property type="entry name" value="ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18073">
        <property type="entry name" value="Rubredoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="5 6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0346">Stress response</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RECA_2" evidence="7">
        <location>
            <begin position="85"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Lon-protease-like" evidence="5">
        <location>
            <begin position="369"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="RadA KNRFG motif" evidence="5">
        <location>
            <begin position="270"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="114"/>
            <end position="121"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD61968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW26949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="470" mass="49420" checksum="396F06CB604A8988" modified="2016-02-17" version="1">MSKAPAKSAASKARTAYVCSECGADYNKWQGQCGECGAWNTLSEFVVEPAVKGGAPNLAASRRASWAGRADAPVVTALKDVTHQEESRVTTGIGEFDRVLGGGLVHGAVVLVGGDPGIGKSTLLLQAITRMAQALPGLYVTGEESLSQVAGRGARLGLPLDGVHALAETCVERILEHASKMKPALIVADSVQTLWTEQLGAAPGSVSQVRESAARLVRYAKETGTSVFLVGHVTKEGGIAGPRVLEHMVDAVLYFEGESGSRFRVLRAFKNRFGAVNELGVFAMSDKGLREVPNPSAIFLSGSRAPQPGSCVMVTREGTRPLLVEVQALVDSSPLSNPRRVAVGMEQNRLAMLLAVLHRHGGVAVGDQDVFVNVVGGIRVQETAADLPVLLAVLSSLRDQPLAEQTIAFGEVGLSGEIRPVPNGEDRLKEAATHGFKRAIVPKGNAPRGGRVGEMEVIAVERLAEAIDAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJB4</accession>
    <name>A0A0S2DJB4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/arginine repetitive matrix 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="GLE_3265"/>
    </dbReference>
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    <dbReference type="PATRIC" id="fig|69.6.peg.3218"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="202" mass="21840" checksum="0312D2A3F196DD29" modified="2016-02-17" version="1">MEAVGRARGASDRIAARAAFASADVPSPASGSKRTRSAAARRRRAPPPRRSRLRFLFCCDTSGLVPAKSGATRSQSVIPAKAGTNRSDATPAPSEAASLQARHSGESRNPFRSPRRKSKATAKWIPAFAGMTARRVRSFRRTHAIATTRFAAPRPSHAARPERSGPRLNRHAPCPPPPPTLDPPAPPRPLSRKPPSSRRTWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJC8</accession>
    <name>A0A0S2DJC8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3282</name>
    </gene>
    <organism evidence="1 2">
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        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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        </lineage>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="ALN58628"/>
        <property type="gene ID" value="GLE_3282"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3282"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3234"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="55" mass="6144" checksum="653B55AD5AEE2D39" modified="2016-02-17" version="1">MWTSLDAVCAAMRRRAQARVFDGGRWGRIRERVDAGSCRFDKRGCECGGFESDGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJD4</accession>
    <name>A0A0S2DJD4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3304</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58650">
        <property type="protein sequence ID" value="ALN58650"/>
        <property type="gene ID" value="GLE_3304"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3304"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3254"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046116">
        <property type="entry name" value="DUF6053"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19523">
        <property type="entry name" value="DUF6053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="73" mass="7667" checksum="8F0511B04F51956A" modified="2016-02-17" version="1">MGTGCDAAITRCASLAYRYGMHRLRMKRRRLSHGFDATGGRADGLVQGPSGPMLFALVGGPSGPMPFARIAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJG2</accession>
    <name>A0A0S2DJG2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
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    <dbReference type="EnsemblBacteria" id="ALN58775">
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        <property type="gene ID" value="GLE_3430"/>
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    <dbReference type="KEGG" id="lez:GLE_3430"/>
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    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BaxI_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="254" mass="27409" checksum="688A4D36AE16DC44" modified="2016-02-17" version="1">MMRSGNPALKESTFLDLGSGAVVTGNGQAMTLNGTVNKTGFLLLLTVLTAAFAWNQIEIGPRGQVSGAGLYLWGGLIGGLVMSLVTTFKKEWSPVTAPMYALLEGFFLGAISSIFEARFPGIVIQAVMLTFGTLFALLAAYRTGLIKATENFKLGVVAATGGIALVYLASIVLRMFNIEIPYIHQSGIIGIGFSLFVVVIAALNLVLDFDFIENGVEQGAPKYMEWYGAFGLMVTLVWLYIEFLRLLSKLQSRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJG3</accession>
    <name>A0A0S2DJG3_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">DUF2063 domain-containing protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">FE772_16430</name>
        <name evidence="2" type="ORF">GLE_3322</name>
    </gene>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948207.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3322"/>
    <dbReference type="EnsemblBacteria" id="ALN58668">
        <property type="protein sequence ID" value="ALN58668"/>
        <property type="gene ID" value="GLE_3322"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3322"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3272"/>
    <dbReference type="OMA" id="LFFNNID"/>
    <dbReference type="OrthoDB" id="1675974at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018640">
        <property type="entry name" value="DUF2063"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044922">
        <property type="entry name" value="DUF2063_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09836">
        <property type="entry name" value="DUF2063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2063" evidence="1">
        <location>
            <begin position="11"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="255" mass="28992" checksum="7127ACC8E4CF381E" modified="2016-02-17" version="1">MSDAPSRLRAQQFELTRHLRDPAASPAPSGIEDRRLAIYRELLFNNIASLLSGNFPAIERILGEQRWERLVRDFYRDHRCHTPLFAEIAREFQRYLQDLDEREPDGLDPPFLLELAHYEWVELALQLSEAQAPRDAAGHDAADLLERAPRLSPLAWPLAYAWPVHRLGPDYQPAQPPPAPTLLLLRREADGEVRFSELSPLAFRLLQRLEESPQLDARAQLRALAAEAGSDDEAGFVEMGAALLRQMRANGVVYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJH4</accession>
    <name>A0A0S2DJH4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3446</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948299.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3446"/>
    <dbReference type="EnsemblBacteria" id="ALN58791">
        <property type="protein sequence ID" value="ALN58791"/>
        <property type="gene ID" value="GLE_3446"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3446"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3394"/>
    <dbReference type="OMA" id="AFACWAV"/>
    <dbReference type="OrthoDB" id="1518706at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009339">
        <property type="entry name" value="DUF998"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06197">
        <property type="entry name" value="DUF998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
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        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
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        <location>
            <begin position="173"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="251" mass="25304" checksum="63F1C19FBFBF0C67" modified="2016-02-17" version="1">MKASSKSAGARSAGPASTSAGAKSADAASAGSTSADPTSSGGKSARAKSAAAPRAAGDARAFALALAAALCCVAALLGFGAALEGYSHWQHPPGLLGARGIPRALAFNLLGYVGPGLVLAWVAWRLAEAARGQRALARIGAWLWLWSALAWAAQGLVVLDPRDLDAQASRLHALAWLLWWLAFAPGAALLAWSALAAPAWRRFGAIALAAAAVVGLAVIAADARLVPAAPAQRVALLAWLAAYLAAARAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJK4</accession>
    <name>A0A0S2DJK4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3429</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58774">
        <property type="protein sequence ID" value="ALN58774"/>
        <property type="gene ID" value="GLE_3429"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3429"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3379"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="53" mass="6128" checksum="708FF7D120087CF6" modified="2016-02-17" version="1">MNAGLAMRPLNFEGLRLLPPTSRRFESRMDYCLRKESIRRSARAPSMSNADRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJM1</accession>
    <name>A0A0S2DJM1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF1232 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_16710</name>
        <name evidence="2" type="ORF">GLE_3386</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948258.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3386"/>
    <dbReference type="EnsemblBacteria" id="ALN58732">
        <property type="protein sequence ID" value="ALN58732"/>
        <property type="gene ID" value="GLE_3386"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3386"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3336"/>
    <dbReference type="OMA" id="WNCEPAL"/>
    <dbReference type="OrthoDB" id="1636222at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="210" mass="23886" checksum="B1C678FE17E91DDB" modified="2016-02-17" version="1">MRMPHPTPTAEPLPFERAPPPHHLQPYEPAMALRPAAIAAFDALLHELHPDAARVDADRLQRLAAWLAALAPEQARHVVDERLRCLQELRTMAADPAWNCEPALRRRLERLFAYVDQDEDLIPDRMPLLGLLDDVLLVELAWPAFAAEAEDYRDFCAYRRLEHPSGDAEAQRAAWARDRLAELALLQHHARVSDSHYANGRTPEPVFRIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJQ8</accession>
    <name>A0A0S2DJQ8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MBL fold metallo-hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Metallo-beta-lactamase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_17350</name>
        <name evidence="2" type="ORF">GLE_3527</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948357.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3527"/>
    <dbReference type="EnsemblBacteria" id="ALN58871">
        <property type="protein sequence ID" value="ALN58871"/>
        <property type="gene ID" value="GLE_3527"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3527"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3471"/>
    <dbReference type="OMA" id="MGYDTRP"/>
    <dbReference type="OrthoDB" id="1815576at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="71"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="296" mass="32684" checksum="26CCD7FCEB6B3A19" modified="2016-02-17" version="1">MKLWSILGNSQKLDGGAMFGNAPRAMWSKWAPPDEHNRIDLACRALLASPLAGKTVLFETGIGAFFEPKLRERYGVVEQRHVLVDSLAQAGFAPADIDVVVLSHLHFDHAGGLLAPWAEGEAPRLLFPNAHYLIGREHYERARHPHPRDRASFIPELPALLEATGRLELVEGEHSRLLGETVRFHYSHGHTPGLMLAEIVGPETLDGQAHGGVVFCADLIPGRPWVHVPITMGYDRNAELLIDEKRAFLSDKLERNVHLFFTHDPGCALAQVVRDDKGKFGTAHEVAELQARALAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJT3</accession>
    <name>A0A0S2DJT3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6 8">Proline iminopeptidase</fullName>
            <shortName evidence="6">PIP</shortName>
            <ecNumber evidence="4 6 8">3.4.11.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Prolyl aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pip</name>
        <name evidence="11" type="ORF">FE772_16885</name>
        <name evidence="10" type="ORF">GLE_3423</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6 8">
            <text>Release of N-terminal proline from a peptide.</text>
            <dbReference type="EC" id="3.4.11.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6 8">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.5" evidence="4 6 8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948284.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3423"/>
    <dbReference type="EnsemblBacteria" id="ALN58768">
        <property type="protein sequence ID" value="ALN58768"/>
        <property type="gene ID" value="GLE_3423"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3423"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3373"/>
    <dbReference type="OMA" id="YDLLCPP"/>
    <dbReference type="OrthoDB" id="665798at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002410">
        <property type="entry name" value="Peptidase_S33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005944">
        <property type="entry name" value="Pro_iminopeptidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43722">
        <property type="entry name" value="PTHR43722"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006431">
        <property type="entry name" value="Pept_S33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00793">
        <property type="entry name" value="PROAMNOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01249">
        <property type="entry name" value="pro_imino_pep_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 10" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="9">
        <location>
            <begin position="36"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR006431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR006431-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN58768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW27064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="321" mass="36164" checksum="A547D377288DAFBF" modified="2016-02-17" version="1">MRELYPEIEPYRTHRLAVDAIHELHVEECGNPDGLPVLFLHGGPGAGVSPYHRRFFDPARYRIVLFDQRGAGKSTPHAELRDNTTWDLVADIERIRALLGIERWVVFGGSWGSTLALAYAQAHPQPVRALVLRGIFLGRPPELRWFNELDGGARWIFPERWQRYLDYIPEEERGQMVEAYWRRLDSDDPQVRREAATAWSDCEGGSTTLLHDPFEPGIHGDTDSAVSVARAEAHYFRHDVFLEPDQLLRDIGRIREIPATIVHGRYDIICPVKSAVDLAAAWPEAELRIVLAGHSAADPAIVDALVTATDTLAERFGSPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK45</accession>
    <name>A0A0S2DK45_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_24560</name>
        <name evidence="4" type="ORF">FE772_16185</name>
        <name evidence="2" type="ORF">GLE_3270</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000096">
        <property type="protein sequence ID" value="OPD61249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948166.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000096.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58616">
        <property type="protein sequence ID" value="ALN58616"/>
        <property type="gene ID" value="GLE_3270"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61249">
        <property type="protein sequence ID" value="OPD61249"/>
        <property type="gene ID" value="BV903_24560"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3270"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3223"/>
    <dbReference type="OrthoDB" id="2208230at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595736" evidence="1">
        <location>
            <begin position="32"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="74" mass="7893" checksum="436612AC9CCC6C1B" modified="2016-02-17" version="1">MFATARRRATAAYLAGFAFCFGLALSLSASASGCSECWDRCFAERRECRQAGNPAAQCQEIFQDCGNGCGCPIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK63</accession>
    <name>A0A0S2DK63_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">R-pyocin-like glycosyl hydrolase family 19</fullName>
            <ecNumber evidence="2">3.2.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_20505</name>
        <name evidence="4" type="ORF">FE772_16445</name>
        <name evidence="2" type="ORF">GLE_3325</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
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        <property type="gene ID" value="BV903_20505"/>
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        <property type="entry name" value="Glyco_hydro_19_cat"/>
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    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
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    <dbReference type="Pfam" id="PF00182">
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    </dbReference>
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            <end position="145"/>
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        <source>
            <dbReference type="Pfam" id="PF00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="203" mass="23246" checksum="578FF3E20B1CD2B2" modified="2016-02-17" version="1">MFAFDDEQFLDGYRKRFGPLRDDLAQAVRFLIGRIERDASFSIDPVHRHQIAYCLATFKWETAHTLRPIDEFGDDARFERLYGPDTRIGKALGNSKRGDGARYHGRGYVQLTGRANYERAGKFLGIDLVGKPEDAKRPEIAYAIAMQGMKQGWFTGKKLDHYFKPGQLPNYEEARRIINGQDKAQTIADIARRFDELLANALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK69</accession>
    <name>A0A0S2DK69_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Secretion protein HlyD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3610</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
    <proteinExistence type="predicted"/>
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            <end position="147"/>
        </location>
    </feature>
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            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="382" mass="40362" checksum="1EAC60F9FD1970FB" modified="2016-02-17" version="1">MSAQRDARNAQTRTASSAAAPASAALIPLRSRALAAAALQDAVASPPAAARSPRRAETPASPRGRAALRSAGLCALAALALAGCARQPPQALGTLEWDRITLPAPAAEKVVRIDVREGQRVKAGARVLQLEPDRTRSQLQAAQAQAQQSAQALAELEAGPRREAIEQARANLAAAQAQQRDASAYFERVRPLGQRRLIAAADVDRARAAAGNALAQVRAAEAGLLELERGNRREDIAQGRAALAAAQAQAAVQQTTFAKLDVVAPRDGVVDSLPYKLGDQAPVGSPLAVMLVGPRPFARVYVPEPIRQDVRVGRAAKVYVEGRARAWNGRVRMIRSEASFTPYYALTGEDAARLSYLCEVELTDADAVELPAGLPVRAEFAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKC5</accession>
    <name>A0A0S2DKC5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF2127 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_18480</name>
        <name evidence="2" type="ORF">GLE_3755</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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            <taxon>Gammaproteobacteria</taxon>
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    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW27330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3755"/>
    <dbReference type="EnsemblBacteria" id="ALN59099">
        <property type="protein sequence ID" value="ALN59099"/>
        <property type="gene ID" value="GLE_3755"/>
    </dbReference>
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    <dbReference type="PATRIC" id="fig|69.6.peg.3699"/>
    <dbReference type="OMA" id="VEAYGLW"/>
    <dbReference type="OrthoDB" id="1920116at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="DUF2127"/>
    </dbReference>
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        <property type="entry name" value="DUF2127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="157" mass="17075" checksum="58FB393FBBC33159" modified="2016-02-17" version="1">MTDPGPHYDTDPKAHPGLHAIAAVEAGKGLLALSAASGLELLGPAPLQRWIELLIHRFHLDPEHGSMAWLAHSISPGSVHLAAGIVFAYAALHLLEAWGLWKAKAWASWLGCLGAALYLPFDLYALARHPGWLAIAVLIINVIVVWVLARDILKRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKD2</accession>
    <name>A0A0S2DKD2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Endoribonuclease YbeY</fullName>
            <ecNumber evidence="9">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 12" type="primary">ybeY</name>
        <name evidence="11" type="ORF">BV903_24270</name>
        <name evidence="12" type="ORF">FE772_17810</name>
        <name evidence="10" type="ORF">GLE_3619</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">C3</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the endoribonuclease YbeY family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000092">
        <property type="protein sequence ID" value="OPD61319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948421.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000092.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3619"/>
    <dbReference type="EnsemblBacteria" id="ALN58963">
        <property type="protein sequence ID" value="ALN58963"/>
        <property type="gene ID" value="GLE_3619"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61319">
        <property type="protein sequence ID" value="OPD61319"/>
        <property type="gene ID" value="BV903_24270"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3619"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3563"/>
    <dbReference type="OMA" id="RMRIHPL"/>
    <dbReference type="OrthoDB" id="1830156at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00009">
        <property type="entry name" value="Endoribonucl_YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023091">
        <property type="entry name" value="MetalPrtase_cat_dom_sf_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002036">
        <property type="entry name" value="YbeY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020549">
        <property type="entry name" value="YbeY_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46986">
        <property type="entry name" value="PTHR46986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02130">
        <property type="entry name" value="YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00043">
        <property type="entry name" value="TIGR00043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01306">
        <property type="entry name" value="UPF0054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3 9" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="8 9" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN58963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OPD61319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW27209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="160" mass="17865" checksum="89CF00B5583679A9" modified="2016-02-17" version="1">MTKGPVRLDVAINYALPRKGLPAAASFRKWVAAALEGRIREADLAIRLVDSKEGRSLNRHYRGRDYATNVLSFPADMPEGLPEGVKLPLLGDLVICAPVVAREAREQKKALNHHYAHLTVHGVLHLLGWDHEDEREAECMEQLEREILATLGVADPYLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKQ3</accession>
    <name>A0A0S2DKQ3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7 9">50S ribosomal protein L16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">rplP</name>
        <name evidence="12" type="ORF">BV903_23000</name>
        <name evidence="14" type="ORF">D9T17_09465</name>
        <name evidence="13" type="ORF">FE772_18615</name>
        <name evidence="11" type="ORF">GLE_3783</name>
    </gene>
    <organism evidence="11 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 15">C3</strain>
        </source>
    </reference>
    <reference evidence="12 16" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 16">B25</strain>
        </source>
    </reference>
    <reference evidence="14 17" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">OH11</strain>
        </source>
    </reference>
    <reference evidence="13 18" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 18">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 9">Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7 9">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000077">
        <property type="protein sequence ID" value="OPD61610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000023">
        <property type="protein sequence ID" value="ROU07188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948549.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3783"/>
    <dbReference type="EnsemblBacteria" id="ALN59127">
        <property type="protein sequence ID" value="ALN59127"/>
        <property type="gene ID" value="GLE_3783"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61610">
        <property type="protein sequence ID" value="OPD61610"/>
        <property type="gene ID" value="BV903_23000"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3783"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3727"/>
    <dbReference type="OMA" id="KGAVEYW"/>
    <dbReference type="OrthoDB" id="1786618at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01342">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_L10e/L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_L10e/L16_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000114">
        <property type="entry name" value="Ribosomal_L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020798">
        <property type="entry name" value="Ribosomal_L16_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220">
        <property type="entry name" value="PTHR12220"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00060">
        <property type="entry name" value="RIBOSOMALL16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="SSF54686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01164">
        <property type="entry name" value="rplP_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00586">
        <property type="entry name" value="RIBOSOMAL_L16_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00701">
        <property type="entry name" value="RIBOSOMAL_L16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="7 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7 9" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="2 7 9" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L16" evidence="10">
        <location>
            <begin position="4"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN59127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OPD61610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW27354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROU07188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="137" mass="15507" checksum="C72A24DAE18E66F7" modified="2016-02-17" version="1">MLQPKRTKYRKVHKGRNEGLSWSGNAVSFGEYGLKATAHGQLTARQIEAARRSISRYVKRGGKMWIRVFPDKPITKKPIEVRMGSGKGNVEYWVAQIQPGRMIYEIEGVPEDVAREAFRLAAAKLSVTTTFVTRTVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKT5</accession>
    <name>A0A0S2DKT5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3917</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948645.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59259">
        <property type="protein sequence ID" value="ALN59259"/>
        <property type="gene ID" value="GLE_3917"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3917"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3854"/>
    <dbReference type="OrthoDB" id="2225133at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="226" mass="23349" checksum="F6D1982CF4BFB8EF" modified="2016-02-17" version="1">MTSPGTPAPGQGGPNRRLAAEIDAREYRRRRPGPILLMGAAVIAALVLTDIVRSNLRQSQIEADAAARAAAQRTAAAAAAAPAATTTATGPSASDRIVGRAFDTMLAELRARSAASAEARERTARYRSLLQRTVAASRLELEIERFECGPHLCIGSLSGDAAAYARFGDAARKAQPPLSAFADWSAAADAGTDAGATQHRFLLPLNAGADADGAPAPAREEPGARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKY7</accession>
    <name>A0A0S2DKY7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SptB protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59223">
        <property type="protein sequence ID" value="ALN59223"/>
        <property type="gene ID" value="GLE_3880"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3880"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3819"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="94" mass="9774" checksum="4972324D413F30CD" modified="2016-02-17" version="1">MAHDAAGRSRAAGPPPGPRRPDRRCVDPATIGGSDDAAGLHAGGDVGIAHLPVSAEDAGLVFNGHRFCVMPAASRDALRAHLRAVRSDMRRDSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLD8</accession>
    <name>A0A0S2DLD8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tol-pal system-associated acyl-CoA thioesterase</fullName>
            <ecNumber evidence="3">3.1.2.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ybgC</name>
        <name evidence="4" type="ORF">FE772_19920</name>
        <name evidence="3" type="ORF">GLE_4057</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948749.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4057"/>
    <dbReference type="EnsemblBacteria" id="ALN59399">
        <property type="protein sequence ID" value="ALN59399"/>
        <property type="gene ID" value="GLE_4057"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4057"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4000"/>
    <dbReference type="OMA" id="YHASYLR"/>
    <dbReference type="OrthoDB" id="1786865at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016790">
        <property type="term" value="F:thiolester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014166">
        <property type="entry name" value="Tol-Pal_acyl-CoA_thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006684">
        <property type="entry name" value="YbgC/YbaW"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003230">
        <property type="entry name" value="YbgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02799">
        <property type="entry name" value="thio_ybgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00051">
        <property type="entry name" value="TIGR00051"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4HBT" evidence="2">
        <location>
            <begin position="29"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="159" mass="17502" checksum="827FF57FA289DDEB" modified="2016-02-17" version="1">MSASEPGSGAVPGLFSWPTRVYWEDTDAGGLVYHAQYVAFMERARSEWVRALGYGQDGLRREHGLLFVVAGMQIGFLAPARLDDELQVAVQLVRCRRASLVFAQRVMRGVQRLVEAEVKVAAVDAQHLRPCPIPPALHAQLQAQEAPQPDALQAASRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLK3</accession>
    <name>A0A0S2DLK3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_20090</name>
        <name evidence="3" type="ORF">GLE_4096</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948778.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4096"/>
    <dbReference type="EnsemblBacteria" id="ALN59438">
        <property type="protein sequence ID" value="ALN59438"/>
        <property type="gene ID" value="GLE_4096"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4096"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4038"/>
    <dbReference type="OMA" id="HYEQVEW"/>
    <dbReference type="OrthoDB" id="1456605at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726676" evidence="1">
        <location>
            <begin position="22"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="535"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="678" mass="73774" checksum="D47EBA6A848F6171" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLP3</accession>
    <name>A0A0S2DLP3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1, 4-benzoquinol</fullName>
            <ecNumber evidence="9">1.14.13.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ubiF</name>
        <name evidence="9" type="ORF">GLE_3903</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UbiH/COQ6 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.-" evidence="9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948635.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3903"/>
    <dbReference type="EnsemblBacteria" id="ALN59245">
        <property type="protein sequence ID" value="ALN59245"/>
        <property type="gene ID" value="GLE_3903"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3903"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3840"/>
    <dbReference type="OMA" id="SDVACII"/>
    <dbReference type="OrthoDB" id="867226at2"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018168">
        <property type="entry name" value="Ubi_Hdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010971">
        <property type="entry name" value="UbiH/COQ6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01988">
        <property type="entry name" value="Ubi-OHases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01304">
        <property type="entry name" value="UBIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="8">
        <location>
            <begin position="8"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN59245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="399" mass="42837" checksum="B9597641CBF42DE4" modified="2016-02-17" version="1">MSRREILDVAVVGAGVVGAAAALAFARDGFDVALVEAREPAPWSPLRPDLRVYAFAPDNAALLQDLGVWSAVRDARAQPYRAMRVWDAAGGGEIAFDADAFGRRELGWIVENGLLVDRLWAALPQAGVQLHCPEYVEALERDGSDSVGVALAGGRRLRARLVVAADGAESKLRRLAGIEAPAHDYGQRGLVAYVDSERSHEATCWQRFLPGGPVAFLPTQGDDGARDRRSSIVWTLPDAEAERLLAADDAAFLGELERAFAGRLGALTKVSARAAFPLRRQLAQRYVSGRVAVIGDAAHVVHPLAGQGVNLGLRDVAGLRASLRQARRHGADPGSPHRLARWARERRSENALAAYGFDGLNKLFSNDDLVATLARGPLLGLAGKLPPLAHFFWRRAAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLS0</accession>
    <name>A0A0S2DLS0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4102</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4102"/>
    <dbReference type="EnsemblBacteria" id="ALN59444">
        <property type="protein sequence ID" value="ALN59444"/>
        <property type="gene ID" value="GLE_4102"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4102"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4044"/>
    <dbReference type="OMA" id="ASACKAM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="266" mass="28917" checksum="D61A50C55CE3E80B" modified="2016-02-17" version="1">MLSLSLAAAFGVAPFGARADDGCGGRSYDLLLAAYPGADSVTGDEGEFLRTAGSPKRWIKLDDVACKVWPAAPGKTLLAVRLRHDEASGDVDTADLEVLVADSAKPRILQRYREREPLVSDAMRISSVTLDTARYRLNEATTAFGVRVTYSGSSRVNPYENTVLSLYAADGDALRPVLSNLEVSLDRGEWDGNCTGEFESVQRTVAIDAKRDHGYAGLRIDTVSQARRNASQNDDCEDISAPKRKSSQRLGFDGRQYAVPRELRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLT4</accession>
    <name>A0A0S2DLT4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4003</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59345">
        <property type="protein sequence ID" value="ALN59345"/>
        <property type="gene ID" value="GLE_4003"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4003"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3940"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="111" mass="11888" checksum="A5CCF03DC2AE2139" modified="2016-02-17" version="1">MYTCVKLPRFMIFGHVMEADPSCWRGTKVNANGGIVMTSGFQLPMGLMGYIKAKAQGVIDAMSEISERQNLKIQAAITSNAASIAGSDFFNAMNADLENFGVGAFISDIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLW8</accession>
    <name>A0A0S2DLW8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_19320</name>
        <name evidence="1" type="ORF">GLE_3937</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948659.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59279">
        <property type="protein sequence ID" value="ALN59279"/>
        <property type="gene ID" value="GLE_3937"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3937"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3874"/>
    <dbReference type="OrthoDB" id="33939at135614"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="217" mass="24225" checksum="93FB83C0BFB41221" modified="2016-02-17" version="1">MANKDASIPPLRTGLSLQAVIEEYLQHGRLRSTAAFGFAPDQSLQELVAGDFKHAAMRPAAYEQIERDVLLRHRGGVVPASLRSTYLRGRYLNSELDLLPGPPLATILRWLSRRRPTPRVELFETFNAEYGAVLVDRSVKFCFTRNGDRYRVTSLMPRIVGSGDDRVALEELDCTLVGMQPCERSADWLARAAQNPKGRQRRAALRAVEGIATLLPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMA6</accession>
    <name>A0A0S2DMA6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_21615</name>
        <name evidence="1" type="ORF">GLE_4426</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949045.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59767">
        <property type="protein sequence ID" value="ALN59767"/>
        <property type="gene ID" value="GLE_4426"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4426"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4364"/>
    <dbReference type="OrthoDB" id="1910120at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="82" mass="9341" checksum="AA58D27C093ED4E5" modified="2016-02-17" version="1">MSEVFVLQHLYRACDGDEESKLLGVYSSRQLAHRAAERFGRQPGFREYAEIVSDGDGDGFYIQAYRLDQDSDGGWSEGFVRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMD4</accession>
    <name>A0A0S2DMD4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_20745</name>
        <name evidence="2" type="ORF">GLE_4236</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948892.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4236"/>
    <dbReference type="EnsemblBacteria" id="ALN59577">
        <property type="protein sequence ID" value="ALN59577"/>
        <property type="gene ID" value="GLE_4236"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4236"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4177"/>
    <dbReference type="OMA" id="GALTFEY"/>
    <dbReference type="OrthoDB" id="1832083at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="282" mass="30143" checksum="3429B853AF61C432" modified="2016-02-17" version="1">MEIRPVGTDAAALASYEALFRACFPGAGHLNAAYLQWLYARNPAGTVIGCDAWEGERLAAHYVCVPAQAVVNGRAMRTMLSLNTATHPDFQGKGLFTRLADATYQLGEQAGIGAVYGVANANSTPGFLRKLGFALVRPLDARVGFGRIERAAPVAAADGFRRDWSQAALEWRIANPQRAYRLVRAGDGAIGAEAATGKPGLLAWDELALPAGMPSPARSPAWAMRLHLGLRPGGGRPQGLWFEIPQRLRPSPLNMIFRPLAEGVAVPAADSVRLGQLDFDAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMF3</accession>
    <name>A0A0S2DMF3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">50S ribosomal protein L13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6 7" type="primary">rplM</name>
        <name evidence="8" type="ORF">BV903_04520</name>
        <name evidence="9" type="ORF">FE772_20865</name>
        <name evidence="7" type="ORF">GLE_4260</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 6">This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000008">
        <property type="protein sequence ID" value="OPD65188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948912.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000008.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4260"/>
    <dbReference type="EnsemblBacteria" id="ALN59601">
        <property type="protein sequence ID" value="ALN59601"/>
        <property type="gene ID" value="GLE_4260"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65188">
        <property type="protein sequence ID" value="OPD65188"/>
        <property type="gene ID" value="BV903_04520"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4260"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4200"/>
    <dbReference type="OMA" id="DFVVIIN"/>
    <dbReference type="OrthoDB" id="1822215at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_L13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005823">
        <property type="entry name" value="Ribosomal_L13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023563">
        <property type="entry name" value="Ribosomal_L13_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_L13_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="PTHR11545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002181">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="SSF52161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01066">
        <property type="entry name" value="rplM_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00783">
        <property type="entry name" value="RIBOSOMAL_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD65188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW27726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="142" mass="16177" checksum="1546EC12952D3067" modified="2016-02-17" version="1">MKTFTAKNETVQRDWYIVDATGKTLGRLSTELARRLRGKHKPVYTPHVDTGDYLVVINAEKIAVTGNKLQDKMYYRFTGYIGNLKSETLGQALERHPERVIEIAVKGMLPKNPLGRAMYRKLKVYKGSEHPHAAQQPQPLDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMG6</accession>
    <name>A0A0S2DMG6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ABC transporter permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Efflux ABC transporter, permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_03290</name>
        <name evidence="4" type="ORF">FE772_21790</name>
        <name evidence="2" type="ORF">GLE_4465</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000006">
        <property type="protein sequence ID" value="OPD65331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949075.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4465"/>
    <dbReference type="EnsemblBacteria" id="ALN59806">
        <property type="protein sequence ID" value="ALN59806"/>
        <property type="gene ID" value="GLE_4465"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65331">
        <property type="protein sequence ID" value="OPD65331"/>
        <property type="gene ID" value="BV903_03290"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4465"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4402"/>
    <dbReference type="OMA" id="IWGDADQ"/>
    <dbReference type="OrthoDB" id="768211at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="309"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="352"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="406"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD65331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="441" mass="45736" checksum="4A11D668368D8206" modified="2016-02-17" version="1">MKKLLSFGRGLLTALALIAGLALWAVAPWPVLVGLAALVALWMLLTRSGQQAASVAGVGISTLRQRLGSSSVVVIGIAGVVAVLVAMLSMAEGYRQTLARTGSADTVLVLRGASAAEVMSTLDLASINVIEQAQGIARGPDGRPLASPETVVAANLPIKGGAPDQDGSVQLRGVGDRAWLVRPQVKIVQGRKFETGKREVVVGSGAQRQFAGLDVGKQIRLGSEQWTVVGVFKSGDAMDSEVWADAEMVAATYRRGASRNAVVAKLTSAKAFKPFKAALAGDPRLQVDVTTTADYFAKQSEGMTTVIRVIGIVVGSIMAIGAVFGALNTMFATVATRAREIATLRAIGFRGLPVVVAVMLETMLLALVGGLIGGVLAWAIFNGYTASTIAGGVGQLTFDFRVTGELLWSGLKWALAIGFVGGLFPALRAATLPVTSALRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DML5</accession>
    <name>A0A0S2DML5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949226.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60011">
        <property type="protein sequence ID" value="ALN60011"/>
        <property type="gene ID" value="GLE_4670"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4670"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4606"/>
    <dbReference type="OrthoDB" id="2044111at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="170" mass="18009" checksum="4BF8853844A9B1C2" modified="2016-02-17" version="1">MNRNDDSDARPGGSRPHPPHSETAAAAREWALQERAREDERRGAPMSEDEPRLAQYRLLSRALRAPPMEPIPYGFAEQVARRAQAAAEAGDGIERWLQRLLLLGLAVAGASLIAGGASEWLPGVDAALRRLPSGIVSWGALAGACCLLSWGWSALARAAGLEPGASARAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMR7</accession>
    <name>A0A0S2DMR7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase H</fullName>
            <ecNumber evidence="6">2.1.1.199</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA m(4)C1402 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">rRNA (cytosine-N(4)-)-methyltransferase RsmH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mraW</name>
        <name evidence="6" type="synonym">rsmH</name>
        <name evidence="8" type="ORF">GLE_4138</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = H(+) + N(4)-methylcytidine(1402) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10286"/>
            <dbReference type="Rhea" id="RHEA-COMP:10287"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74506"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.199"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the methyltransferase superfamily. RsmH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.199" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4138"/>
    <dbReference type="EnsemblBacteria" id="ALN59480">
        <property type="protein sequence ID" value="ALN59480"/>
        <property type="gene ID" value="GLE_4138"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4138"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4080"/>
    <dbReference type="OMA" id="STKMRWA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071424">
        <property type="term" value="F:rRNA (cytosine-N4-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01007">
        <property type="entry name" value="16SrRNA_methyltr_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002903">
        <property type="entry name" value="RsmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023397">
        <property type="entry name" value="SAM-dep_MeTrfase_MraW_recog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11265">
        <property type="entry name" value="PTHR11265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01795">
        <property type="entry name" value="Methyltransf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004486">
        <property type="entry name" value="MraW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81799">
        <property type="entry name" value="SSF81799"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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            <begin position="253"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="5"/>
        </location>
        <ligand>
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        </ligand>
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        <location>
            <position position="31"/>
        </location>
        <ligand>
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        <location>
            <position position="57"/>
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        <ligand>
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        </ligand>
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    <evidence type="ECO:0000256" key="1">
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        </source>
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    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN59480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="295" mass="31246" checksum="67A53BA14DA22FC1" modified="2016-02-17" version="1">MLVMDKDPEAIAVAEREFGADPRVSIHRGSFAELAHWDATAGGLDGVLLDLGVSSPQLDVAERGFSFGKDGPLDMRMDPDSGQSAAQWLNSAAEKDIADVLWTYGEERQSRRIARAILARRAAQPLARTAELAEVIAQAMPRGDQKIHPATRSFQAIRIFINRELADLEAGLDAALARLKPGGRLAVISFHSLEDRIVKQFIVRHSKAPPSNRRLPVEIAFTPTLLAVGGAQKADEDELATNPRARSAVLRVAEKLGAAGPGTGDRGPGKAEADVSGHSRVPGPGSPVPSAGGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMY0</accession>
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        <name type="scientific">Lysobacter enzymogenes</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 6">C3</strain>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        </location>
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            <begin position="2609"/>
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        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
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            <dbReference type="PROSITE" id="PS51208"/>
        </source>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
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    <sequence length="2629" mass="244327" checksum="27B4162855CB01B2" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN22</accession>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <begin position="48"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59789.1"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="QCW27876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="172" mass="17330" checksum="2DB2659EEB6ADFD3" modified="2016-02-17" version="1">MSNGNGVTATLTQAAENVKETASNLGSAIATRAEEAVASVKQTATRARKAAKKAVGTAKKKLAKASAEAKKEVSALKAKATGKKAAAKKTAKKAAKKVAKKAAKKVATKKAAAKKAVKKAVKKVAAKSPAKKAAKKAVAKKAPAKKAVKKAAAKKAAKKAPAKKAAKKAAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN54</accession>
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        <submittedName>
            <fullName evidence="4">DUF3016 domain-containing protein</fullName>
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        <name evidence="4" type="ORF">FE772_22990</name>
        <name evidence="3" type="ORF">GLE_4729</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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        </location>
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        <location>
            <begin position="24"/>
            <end position="190"/>
        </location>
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        <location>
            <begin position="22"/>
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        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="190" mass="21557" checksum="68A376EC1A3482A0" modified="2016-02-17" version="1">MTLRTAWLALAAAAVLASGAAGAKSRTVTDPDAPRALPEQGPVSVRWENPEQFAEIRQSRNRFDARRGNWVEQIAQHVRKRGERELAPGQRLAVDITDIKRAGDYEPWHGPQFDDTRFVRDIYPPRIALSFTLTDANGQVIEQGERTLRDLSFLMGPRSATESDPLRYEKRLIDDWMNREFKADARSAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN88</accession>
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            <fullName evidence="2">Cell shape-determining protein MreC</fullName>
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        <alternativeName>
            <fullName evidence="4">Cell shape protein MreC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">mreC</name>
        <name evidence="6" type="ORF">GLE_4512</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MreC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949111.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4512"/>
    <dbReference type="EnsemblBacteria" id="ALN59853">
        <property type="protein sequence ID" value="ALN59853"/>
        <property type="gene ID" value="GLE_4512"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4512"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4448"/>
    <dbReference type="OMA" id="NPFTHRI"/>
    <dbReference type="OrthoDB" id="837894at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042177">
        <property type="entry name" value="Cell/Rod_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042175">
        <property type="entry name" value="Cell/Rod_MreC_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007221">
        <property type="entry name" value="MreC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34138">
        <property type="entry name" value="PTHR34138"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04085">
        <property type="entry name" value="MreC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00219">
        <property type="entry name" value="mreC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="294"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="294"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="318"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="406" mass="42610" checksum="809567970811D867" modified="2016-02-17" version="1">MPPYAGPPTAARSGEVADTLRLMAYLALALTLIVLDHRGGWLSQARKQAATLVAPLWAVAGWPGRLVERVSDDAGTLSQLTDENRRLRNEALLNQARMARLQSVAADNQRLRGLLEVAERGNLDVVLAPILDIDLDPSRQRLILDAGSRERLRVGQSVIDAGGLIGQVTGITPLHSSVLLITDPSHAVPVNVARNGVRLVVYGEGRSDRLTLRSVPLSSDVRVGDVVVTSGLGGRFPPGFPVGTIAALKPDDSRAFLVGEVKPAAQLDRGREVLVLLSLPPPPVDTQDFDTQPAVAETASASTPEAQAAAEQAAAQRLSELKQRKPKARSATSPEELKSEIEPAPPAAAARSNAGASGNAPAGSRNAAAPAARPSAQRAPANVPATSAPPAAARPQPRNARQEPQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNE1</accession>
    <name>A0A0S2DNE1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4588</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59929">
        <property type="protein sequence ID" value="ALN59929"/>
        <property type="gene ID" value="GLE_4588"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4588"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4524"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046116">
        <property type="entry name" value="DUF6053"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19523">
        <property type="entry name" value="DUF6053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="64" mass="6858" checksum="CAB7AAE87E60911A" modified="2016-02-17" version="1">MGVGRASGLGLWFRIAATAARGIGPEGPPTTALAWAGAMSCATKRHRRSRGDAVPCRYFVRAWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNJ7</accession>
    <name>A0A0S2DNJ7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 9 10">Transaldolase</fullName>
            <ecNumber evidence="5 9 10">2.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">talA</name>
        <name evidence="9 12" type="synonym">tal</name>
        <name evidence="12" type="ORF">FE772_23665</name>
        <name evidence="11" type="ORF">GLE_4873</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9 10">Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9 10">
            <text>D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D-fructose 6-phosphate + D-erythrose 4-phosphate</text>
            <dbReference type="Rhea" id="RHEA:17053"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9 10">Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 9 10">Belongs to the transaldolase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.2" evidence="5 9 10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949378.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4873"/>
    <dbReference type="EnsemblBacteria" id="ALN60214">
        <property type="protein sequence ID" value="ALN60214"/>
        <property type="gene ID" value="GLE_4873"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4873"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4804"/>
    <dbReference type="OMA" id="ICKFAED"/>
    <dbReference type="OrthoDB" id="784333at2"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00414"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004801">
        <property type="term" value="F:transaldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00957">
        <property type="entry name" value="Transaldolase_TalAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00492">
        <property type="entry name" value="Transaldolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004730">
        <property type="entry name" value="Transaldolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018225">
        <property type="entry name" value="Transaldolase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="PTHR10683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683:SF18">
        <property type="entry name" value="PTHR10683:SF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00874">
        <property type="entry name" value="talAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01054">
        <property type="entry name" value="TRANSALDOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00958">
        <property type="entry name" value="TRANSALDOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9 10" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0704">Schiff base</keyword>
    <keyword evidence="6 9 10" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN60214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW28195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="317" mass="34078" checksum="87E3FF49ED117C56" modified="2016-02-17" version="1">MSNRLEQLRQLSAVVADTGDIEAIARFHPLDATTNPSLLLKAASLPAYAPLIDAAVAQARGGDAQARVADAGLRLAVAIGGEILKLIPGRVSTEVDARLSFDTQASLDQARRIVELYDAAGIGRDRLLIKVASTWEGIRAAEQLEREGIHCNLTLLFSFAQAVACAEAGVYLISPFVGRILDWHLANGAAKPATPQDDPGVQSVARIWNYYKRHGYDTVVMGASFRNVGQVLALAGCDRLTISPELLGELEGSDGDVPRALEDDGARAASGERLSEAAFRWQHNEDAMATDKLADGIRRFAADQRKLEDLLAQRLNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNL6</accession>
    <name>A0A0S2DNL6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4837</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60178">
        <property type="protein sequence ID" value="ALN60178"/>
        <property type="gene ID" value="GLE_4837"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4837"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="58" mass="7022" checksum="3FFF87080BA88FB1" modified="2016-02-17" version="1">MDYPHRVSFRRLDEWCEVSTQRGRRAAVPRGMIRMRAATLRRMRGRQPRLRRVPTSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNT0</accession>
    <name>A0A0S2DNT0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4863</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949372.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4863"/>
    <dbReference type="EnsemblBacteria" id="ALN60204">
        <property type="protein sequence ID" value="ALN60204"/>
        <property type="gene ID" value="GLE_4863"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4863"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4795"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021455">
        <property type="entry name" value="DUF3106"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11304">
        <property type="entry name" value="DUF3106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="230" mass="25313" checksum="7AF081B2322EF3C2" modified="2016-02-17" version="1">MSRTTVARTFCSGARFGAAWSRMPWFGAAALATALALSAPARALPPELERSLARLPAPVQARIRANGARWDGWSEAQRHEFAQRAAHWNQLDAAERGARRERYLAWQALSADERAQAQAAAARYAALPPEQRQALRAQFDALDRSERRGWLLGPTLGADYPALQPLLAQLPQEQHATLLAALRGLSAAQRKDLAVLVQRTPPQERERLRAGLLATPAAQRGTWLHDALAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNZ5</accession>
    <name>A0A0S2DNZ5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4888</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60229">
        <property type="protein sequence ID" value="ALN60229"/>
        <property type="gene ID" value="GLE_4888"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4888"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4819"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="191" mass="20095" checksum="A48C97F490E6833C" modified="2016-02-17" version="1">MRARTVAVRCARGGRRDRREGGPVAAEADAMSAGAGAAARRNAIAVAAVWVAGLACTVWINRGGVAWGLPAIAAAACACCLALEWWPRAWPARAAQSLLWIALFCLALVPPLYTVIADTALALNPNRFMCDVGDRMVRCGMIGIEALAVPCVVLAAAVVCRIRWRDAEVERIATAVALAIALVWTALAVAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP15</accession>
    <name>A0A0S2DP15_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Response regulator transcription factor</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Transcriptional regulatory protein, C terminal-DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_23260</name>
        <name evidence="5" type="ORF">GLE_4780</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949310.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4780"/>
    <dbReference type="EnsemblBacteria" id="ALN60121">
        <property type="protein sequence ID" value="ALN60121"/>
        <property type="gene ID" value="GLE_4780"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4780"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4714"/>
    <dbReference type="OMA" id="MCAHVLV"/>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="124"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="124"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW28133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="230" mass="24928" checksum="04CA7607AA274ABE" modified="2016-02-17" version="1">MRILLVEDNADLADAIVRRMRRDGHAVDWQSDGLKADSVLRYQGFDLIVLDIGLPRLDGLGLLAGLRERGDATPVLMLTARDGIDDRVRALDSGADDYLSKPFDFREFEARCRVLLRRNRGQAAGTVQVGGFAFDAGAHRVTLDGEPIELPNREFRLLEILIGKLGQVVSKDEIGNGLFGFDDEAGPNAIELYVGRLRKKLAAAPLRIVTVRGAGYMIEAGAAAEGGGDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP49</accession>
    <name>A0A0S2DP49_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_4973</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949454.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4973"/>
    <dbReference type="EnsemblBacteria" id="ALN60314">
        <property type="protein sequence ID" value="ALN60314"/>
        <property type="gene ID" value="GLE_4973"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4973"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4900"/>
    <dbReference type="OMA" id="HVMTLVL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="253"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="279"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="303"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="342"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="371"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="420"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="640"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="666"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="692"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="723"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="751"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="domain" description="MMPL" evidence="7">
        <location>
            <begin position="176"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN60314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="790" mass="83695" checksum="05A42A0B50D70C43" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPK4</accession>
    <name>A0A0S2DPK4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5076</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5076"/>
    <dbReference type="EnsemblBacteria" id="ALN60417">
        <property type="protein sequence ID" value="ALN60417"/>
        <property type="gene ID" value="GLE_5076"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5076"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5003"/>
    <dbReference type="OMA" id="GVWFPEH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="358" mass="37521" checksum="FBC4E9625000B649" modified="2016-02-17" version="1">MNIATVSSATPAPSAAVSDAAALAPVLIVGGSGVVGAQGAQALRRLHPQLPLAIAGRDRARAEAVAARVGGASALAVDLQREDLGLPADARFSAVVVFVKDDTLNTLKYALHRRLPYVSTSSGSFEIAPEVSLHLRHPGRSPMLLASHWLAGAATLPALHFAAALRRVERIGLFALLDERDMGGPAAAADYQRLTSAAAAQILERGRWRWVRGEQAAGAGVSVDGTPMPAQAYSPMDVVSLAAATGAHSIRLDLALGETASRRRGEAFSTEIAIELEGEDADGRRVRTRHELVHPQGQAPLTALGIALGVERLLGLDGAEAPAPGLYTPDLLIEPGYFLRRLQEAGLRVVERGVSVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPR7</accession>
    <name>A0A0S2DPR7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_5374</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5374"/>
    <dbReference type="EnsemblBacteria" id="ALN60715">
        <property type="protein sequence ID" value="ALN60715"/>
        <property type="gene ID" value="GLE_5374"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5374"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5289"/>
    <dbReference type="OMA" id="WPGGGWY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595537" evidence="2">
        <location>
            <begin position="26"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="389" mass="40525" checksum="207C66A6C4124470" modified="2016-02-17" version="1">MERQRLARLLLAALLPAGACAAAHAQETQAATDAATAKTVEQAAQTPAAQNAAQAPVAATPAAPAAPATPAVPATGTETPAAAPPAEPPAAAKPTVERTTEKVAQPPAERAAAERIADKPAEAAKDAAKPAARKPAPATGAGGPLKNVVAGSWRDPANVARDGYRHPLETLQFFGVRADQTVVEITPGGGWYSEILAPYLREKGRYVAAVVDPDSQTKDSSRAYFAKAKSGLEKKFAAAPAQYGGAVIAAYDPFKPAFGAPASADVVLTFRNVHNWRSAGQAEVMFKGFYDVLKPGGTLGVVEHRAKGDVPAEDKSGYVGQAQVIALAEAAGFRLEGKSEVNANPRDTKDYPNGVWTLPPSNQHEAADGAKYKAIGESDRMTLRFRKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPU0</accession>
    <name>A0A0S2DPU0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SCO family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">SCO1/SenC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_24855</name>
        <name evidence="4" type="ORF">GLE_5126</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SCO1/2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949575.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5126"/>
    <dbReference type="EnsemblBacteria" id="ALN60467">
        <property type="protein sequence ID" value="ALN60467"/>
        <property type="gene ID" value="GLE_5126"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5126"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5051"/>
    <dbReference type="OMA" id="FELNGWM"/>
    <dbReference type="OrthoDB" id="1994201at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd02968">
        <property type="entry name" value="SCO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003782">
        <property type="entry name" value="SCO1/SenC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12151">
        <property type="entry name" value="PTHR12151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02630">
        <property type="entry name" value="SCO1-SenC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="41"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW28400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="200" mass="22139" checksum="44987A5C6FAA4800" modified="2016-02-17" version="1">MRDHPALPSRRRLLAAAGAAALLSACGEQEPKLRLHGIDLSQRPGFGGDFRLSDPDGRERTLSDFYGRAVLLFFGFTLCPDVCPTALTRAVQIRKLLGADGQRLQVLFVTLDPERDTPQVLRAYTQAFDPSFIGLSGSEQRIAETTKAFRVVYAKVPTGSTYTIDHSALSYVYDARGRLRMALRHEQSAAECVDDIRQIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPU2</accession>
    <name>A0A0S2DPU2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RecBCD enzyme subunit RecB</fullName>
            <ecNumber evidence="8">3.1.11.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Exonuclease V subunit RecB</fullName>
            <shortName evidence="8">ExoV subunit RecB</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Helicase/nuclease RecBCD subunit RecB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 13" type="primary">recB</name>
        <name evidence="13" type="ORF">GLE_5231</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>Exonucleolytic cleavage (in the presence of ATP) in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides.</text>
            <dbReference type="EC" id="3.1.11.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.5" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5231"/>
    <dbReference type="EnsemblBacteria" id="ALN60572">
        <property type="protein sequence ID" value="ALN60572"/>
        <property type="gene ID" value="GLE_5231"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5231"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5149"/>
    <dbReference type="OMA" id="KQSIYRW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008854">
        <property type="term" value="F:exodeoxyribonuclease V activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01485">
        <property type="entry name" value="RecB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038726">
        <property type="entry name" value="PDDEXK_AddAB-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004586">
        <property type="entry name" value="RecB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070:SF23">
        <property type="entry name" value="PTHR11070:SF23"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12705">
        <property type="entry name" value="PDDEXK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00609">
        <property type="entry name" value="recB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51217">
        <property type="entry name" value="UVRD_HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 8" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="8 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="8 9 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="11">
        <location>
            <begin position="19"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="12">
        <location>
            <begin position="516"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="DNA-binding and helicase activity, interacts with RecC" evidence="8">
        <location>
            <begin position="1"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Nuclease activity, interacts with RecD and RecA" evidence="8">
        <location>
            <begin position="927"/>
            <end position="1216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="940"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="active site" description="For nuclease activity" evidence="8">
        <location>
            <position position="1122"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="985"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="1109"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
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        <location>
            <position position="1122"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN60572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1216" mass="131391" checksum="6ACEFBD4F9998EDC" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPV1</accession>
    <name>A0A0S2DPV1_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">GLE_5271</name>
    </gene>
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        <name type="scientific">Lysobacter enzymogenes</name>
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            <taxon>Proteobacteria</taxon>
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    </organism>
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            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
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    </dbReference>
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        <location>
            <begin position="47"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="86" mass="9222" checksum="A48AE055923326C6" modified="2016-02-17" version="1">MDRRRIGGCLACFGFGFGFGFGFDLCFNSSRCHCRCRCSRSWLGRDPERGHGSAAPKGARMDARARHGTGCPLWRGPAPGAGLSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPZ8</accession>
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        <submittedName>
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        <name evidence="1" type="ORF">GLE_5319</name>
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        <name type="scientific">Lysobacter enzymogenes</name>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">C3</strain>
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    </reference>
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        <property type="gene ID" value="GLE_5319"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5319"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="99" mass="10772" checksum="C9B8776DBD63DB8B" modified="2016-02-17" version="1">MDSARKTQLSQARLSMQPAAIKGRGAASFVDGRFAVRTAHGEDDGWGSVYEDADLAPRPDTVVTEETARSIISRNDSPDIAFGQSVNPYRGCEHGMVMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ09</accession>
    <name>A0A0S2DQ09_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Endonuclease</fullName>
            <ecNumber evidence="4">3.1.-.-</ecNumber>
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        <submittedName>
            <fullName evidence="5">Exonuclease domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_25210</name>
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    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN60547">
        <property type="protein sequence ID" value="ALN60547"/>
        <property type="gene ID" value="GLE_5206"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5206"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5125"/>
    <dbReference type="OMA" id="CRELTHI"/>
    <dbReference type="OrthoDB" id="1985371at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
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        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="3">
        <location>
            <begin position="11"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW28458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="195" mass="21727" checksum="0069DEC0CEC9FF25" modified="2016-02-17" version="1">MNETIERQPTLYLLIDFEATCADDGAVPRHQMEIIEIGAVMVDTASLAVVGEFQSFVRPVRHPRLTAFCTRLTSIAQADVDAAPGFAEAAAALKAWRGGYADLVWGSWGDYDRNQLQQDCDFHRVSNPVGAPHHNIKRLFAQREGSGRKFGLDGGVKRVRLDFAGTHHRGIDDARNIARLLPYALGRAEFPRERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQB2</accession>
    <name>A0A0S2DQB2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HlyD secretion family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_5413</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949793.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5413"/>
    <dbReference type="EnsemblBacteria" id="ALN60754">
        <property type="protein sequence ID" value="ALN60754"/>
        <property type="gene ID" value="GLE_5413"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5413"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5329"/>
    <dbReference type="OMA" id="VYIDANF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="51"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="390"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="84"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="404"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="452" mass="47314" checksum="03232F0F054616F0" modified="2016-02-17" version="1">MPLKTPFKSKATIPALLIALLAVLVILYAWRLWPFSSARQTTENAYVRGSVTVIAPKVDGYVAQVRVQDYMQVKAGQVLVELDARNYRQRLDQAQANLAAQQANLSNSTQAQRVREAAVANVDAQLKAAQANLARAQADMRRAEALVGDGSLSKRERDQTLAALRQAEASMGQAQAARRSADEDVRSVIVNRDALTAAVANARAALKLAEIDLANTRILAPQDGQLGEIGVRLGQYVTPGTQLMQLVPHRVWVVANFKESQTAGIRPGQAAWFRVDALDGKTLRGRVERLSPATGSEFSVIKTDNATGNFTKVAQRLPVRIALEPGRDEAERALVARLRPGMSVEATVDTASAIDADAVRRAEQAAAADAARDASVPALQADDGAASAGAAAGAAASPPSSAGPADDEASSGTLSNGGPANDASSHSAPSPAGPPDAAAAKRDPANHGTPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQF4</accession>
    <name>A0A0S2DQF4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5308</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949708.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5308"/>
    <dbReference type="EnsemblBacteria" id="ALN60649">
        <property type="protein sequence ID" value="ALN60649"/>
        <property type="gene ID" value="GLE_5308"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5308"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5226"/>
    <dbReference type="OMA" id="GEYHAKN"/>
    <dbReference type="OrthoDB" id="1322015at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025737">
        <property type="entry name" value="Phenol_MetA_deg_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13557">
        <property type="entry name" value="Phenol_MetA_deg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595975" evidence="1">
        <location>
            <begin position="29"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="287" mass="31894" checksum="4DDE825788062624" modified="2016-02-17" version="1">MPHTSLRRAALRCVASLALLSCALPAAAAGLPDPGDYAAPPPGVRILALYAQHNWADAFYARGDKAVDGLDLELDVAVARYMHYFQVGGRTADVEVILPYARQRIGLDGYRERGLGNPSVGATLWTHADQTRGEYLGWAAYLSLPLGQHRDRGFAVSEDRYALDLEVGYVRKLNDRWSLDLIGQAEFYTADRSTDVRRRPMLRGIGHLSYHVSDKTRLALSLRQTFGMRERLHGEQVAGARNDTNAMLTWAYQASDATQVQVQYAHDLRVREGVRADALQARLVLAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DRB6</accession>
    <name>A0A0S2DRB6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5387</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60728">
        <property type="protein sequence ID" value="ALN60728"/>
        <property type="gene ID" value="GLE_5387"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5387"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5302"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="39" mass="4144" checksum="F98CB756B5D01AA3" modified="2016-02-17" version="1">MARRAGRPLSRFGGREAKCGGGPLRFGVAGRACYRGGYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DRJ0</accession>
    <name>A0A0S2DRJ0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Insertion sequence transposase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5467</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949830.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60808">
        <property type="protein sequence ID" value="ALN60808"/>
        <property type="gene ID" value="GLE_5467"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5467"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5382"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025161">
        <property type="entry name" value="Put_IS4/IS5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13340">
        <property type="entry name" value="DUF4096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="138" mass="16021" checksum="43A5B71944BC0815" modified="2016-02-17" version="1">MEHDPTPRDDAATAAANAQRRAIALDDGEWEAFKRALGEPALVRAGSERDDRRFVDAALSVMTGHCYWTDLPAQDYGNWVSNYRRNRRWMARGVWLRALRSGALPQAWAQRIAQYAQRQDQERARRGARKRERLLRQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA84</accession>
    <name>A0A0S2DA84_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein U domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0103</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0103"/>
    <dbReference type="EnsemblBacteria" id="ALN55462">
        <property type="protein sequence ID" value="ALN55462"/>
        <property type="gene ID" value="GLE_0103"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0103"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.107"/>
    <dbReference type="OMA" id="TVWGSTT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007893">
        <property type="entry name" value="Spore_coat_U"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05229">
        <property type="entry name" value="SCPU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00972">
        <property type="entry name" value="SCPU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCPU" evidence="1">
        <location>
            <begin position="91"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="155" mass="15481" checksum="4A1DB19A83D7BB17" modified="2016-02-17" version="1">MALAAAGPAFAASDTANLNVTITITSVCDIHTTAPLPVNFGSVSSSATNVDQQGQLTVNCTPGTAYTIGLDNGQNGTDVNSRKMANGANLVPYQLYRAAARGPGDVWGSTVGAGGNVLAGSGTGAAVNVPVYGRTPSANFPAGTYNDVVIATITY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAI0</accession>
    <name>A0A0S2DAI0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histidine kinase</fullName>
            <ecNumber evidence="4">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BV903_22630</name>
        <name evidence="14" type="ORF">GLE_0164</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">C3</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">B25</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000076">
        <property type="protein sequence ID" value="OPD61627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945840.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000076.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0164"/>
    <dbReference type="EnsemblBacteria" id="ALN55523">
        <property type="protein sequence ID" value="ALN55523"/>
        <property type="gene ID" value="GLE_0164"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61627">
        <property type="protein sequence ID" value="OPD61627"/>
        <property type="gene ID" value="BV903_22630"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0164"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.166"/>
    <dbReference type="OMA" id="LEVWDRG"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Fernandez C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        <source>
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        <source>
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</entry>
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                <person name="Feng T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726524" evidence="2">
        <location>
            <begin position="22"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="199" mass="20942" checksum="DD7B8A5E5998CBC3" modified="2016-02-17" version="1">MKHFAHIAVLALLAVAAPGYAAQERPDAKDRKADAAGSSASAPAAGSDRLVPNEVSGDDCAADARIGVAPDEPMRRLHVRLCEAQVQPAYRARCGESARELASIPFVTDHCGSLDEPVEVALGGRSYRLRRIGAEPAAGAPRLAGTFAGDGLRMQVKPGRVIQQRVEDGEPIGIEQEVTVTLRLDGAKRTLPAVYSDGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBK5</accession>
    <name>A0A0S2DBK5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55688">
        <property type="protein sequence ID" value="ALN55688"/>
        <property type="gene ID" value="GLE_0330"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0330"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.327"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="40" mass="4619" checksum="222BD67EB457CF32" modified="2016-02-17" version="1">MRTPSGAAEHGLRVGLRPSEWQRQLQQQQQKQNGFQLSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBM5</accession>
    <name>A0A0S2DBM5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_03415</name>
        <name evidence="1" type="ORF">GLE_0540</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946110.1">
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_0540"/>
    <dbReference type="EnsemblBacteria" id="ALN55898">
        <property type="protein sequence ID" value="ALN55898"/>
        <property type="gene ID" value="GLE_0540"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0540"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.534"/>
    <dbReference type="OMA" id="CFTRFPL"/>
    <dbReference type="OrthoDB" id="1542724at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="195" mass="22280" checksum="04A23DED5E830FE8" modified="2016-02-17" version="1">MIVIRHRRNTLAELRATPADLGIELDLRSRGEELIVHHDAFADGERFEDWLAGFRHRTLILNVKEEGLEDRLIALMRERGIEDYFFLDQSFPFLVRTAHRGESRCAVRVSEFESIDTALSLAGRIQWVWVDCFTRFPLDAAQARRLQDAGLKLCLVSPELQGRDAGSEIPALRALLAREGIVAEAVCTKEPELWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBN3</accession>
    <name>A0A0S2DBN3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-demethylubiquinone-9 3-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.64</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0529</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.64" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946100.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0529"/>
    <dbReference type="EnsemblBacteria" id="ALN55887">
        <property type="protein sequence ID" value="ALN55887"/>
        <property type="gene ID" value="GLE_0529"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0529"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.524"/>
    <dbReference type="OMA" id="NGHYSFD"/>
    <dbReference type="OrthoDB" id="1515497at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008689">
        <property type="term" value="F:3-demethylubiquinone-9 3-O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="45"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="248" mass="27851" checksum="918287648D1F5AAB" modified="2016-02-17" version="1">MTQHNAAQFEALADLYEDISDWPFRKYIETPSVLARIGDVAGADVLDFGCGAGTYARMFKRAGARRVVGYDLAEGMLASARRRAAAERLDVEFVSALGPDQAGRFDLVLAVYVLPYAQALPDLERMCFQMLAPLRPGGRLIALPIHPDYEPAPSYYEPFGFRMTPDDPREPHRDGARLRLDLFYQQRYDASVHAWYWSRSAIETALHRAGATAVRWHPPQLHAPADAPPELQAYVRRPHAAIVECRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBZ3</accession>
    <name>A0A0S2DBZ3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF2061 domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_04090</name>
        <name evidence="2" type="ORF">GLE_0681</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946211.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0681"/>
    <dbReference type="EnsemblBacteria" id="ALN56039">
        <property type="protein sequence ID" value="ALN56039"/>
        <property type="gene ID" value="GLE_0681"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0681"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.669"/>
    <dbReference type="OMA" id="FHEKVWK"/>
    <dbReference type="OrthoDB" id="1574819at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018638">
        <property type="entry name" value="DUF2061_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09834">
        <property type="entry name" value="DUF2061"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2061" evidence="1">
        <location>
            <begin position="2"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="72" mass="7673" checksum="2699CA8FFF7491A2" modified="2016-02-17" version="1">MEKTLSFAGVHFTVAFLVGYLMTGSVWVGGALALVEPACNTVAFHLHEKVWKRIERRRAAAAATVGGDALAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC72</accession>
    <name>A0A0S2DC72_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56123">
        <property type="protein sequence ID" value="ALN56123"/>
        <property type="gene ID" value="GLE_0765"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0765"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.753"/>
    <dbReference type="OMA" id="TYEDRYR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="159" mass="16849" checksum="2A0A41D13DA256E9" modified="2016-02-17" version="1">MKREHFKRTAKIGFWALLLSAYSVGAAGVMIDVFGADYRELGQVAVTSVDSKPTRRSLSAAQIAAVYRAQSGAPFSTLPPGSTFKVVWPDGSSEYVMVVSPSSTGGVQPIPGTQVPAKGKKKHGPVEDDDAPPRNVPGATELSETDVKEMAAWMDAAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCB4</accession>
    <name>A0A0S2DCB4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">3-dehydroquinate dehydratase</fullName>
            <shortName evidence="8">3-dehydroquinase</shortName>
            <ecNumber evidence="6 8">4.2.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Type II DHQase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">aroQ</name>
        <name evidence="14" type="ORF">D9T17_23325</name>
        <name evidence="13" type="ORF">FE772_04525</name>
        <name evidence="12" type="ORF">GLE_0769</name>
    </gene>
    <organism evidence="12 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">C3</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">OH11</strain>
        </source>
    </reference>
    <reference evidence="13 17" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8">Catalyzes a trans-dehydration via an enolate intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>3-dehydroquinate = 3-dehydroshikimate + H2O</text>
            <dbReference type="Rhea" id="RHEA:21096"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="EC" id="4.2.1.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 3/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 8">Homododecamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the type-II 3-dehydroquinase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.10" evidence="6 8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000058">
        <property type="protein sequence ID" value="ROU04580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946286.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000058.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0769"/>
    <dbReference type="EnsemblBacteria" id="ALN56127">
        <property type="protein sequence ID" value="ALN56127"/>
        <property type="gene ID" value="GLE_0769"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0769"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.758"/>
    <dbReference type="OMA" id="AYTHYSY"/>
    <dbReference type="OrthoDB" id="1872106at2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00086"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003855">
        <property type="term" value="F:3-dehydroquinate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00466">
        <property type="entry name" value="DHQase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.9100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00169">
        <property type="entry name" value="AroQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001874">
        <property type="entry name" value="DHquinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018509">
        <property type="entry name" value="DHquinase_II_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036441">
        <property type="entry name" value="DHquinase_II_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21272">
        <property type="entry name" value="PTHR21272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01220">
        <property type="entry name" value="DHquinase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001399">
        <property type="entry name" value="DHquinase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52304">
        <property type="entry name" value="SSF52304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01088">
        <property type="entry name" value="aroQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01029">
        <property type="entry name" value="DEHYDROQUINASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7 8 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="102"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="23"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8 9">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8 11">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001399-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001399-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001399-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN56127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW25045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROU04580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="146" mass="15508" checksum="B61390729DA8A72D" modified="2016-02-17" version="1">MAKLLVLHGPNLNLLGTREPEVYGRTTLAEIDAGLAAGAAQAGHALESLQSNAEHVLVDRVQAARADGTALILINPAAFTHTSVAIRDALAAVAIPFIEIHLSNPHTREPFRRHSYFSDLAVGVVCGFGADSYRYALEAAIKRLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCB5</accession>
    <name>A0A0S2DCB5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0792</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56150">
        <property type="protein sequence ID" value="ALN56150"/>
        <property type="gene ID" value="GLE_0792"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="53" mass="5810" checksum="BADE879E69DD2490" modified="2016-02-17" version="1">MAPRVALDRSLFAGRAPKPPRVRPARTRGDRAGTPVWTLRARSREAADKNAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCF2</accession>
    <name>A0A0S2DCF2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0851"/>
    <dbReference type="EnsemblBacteria" id="ALN56209">
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        <property type="gene ID" value="GLE_0851"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0851"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594733" evidence="1">
        <location>
            <begin position="25"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="176" mass="18565" checksum="7630104344F20B97" modified="2016-02-17" version="1">MRRLLPAFGAAMALAAFVSPAAFAADPVPEIQRSGSVPAQPAGSVHTLRQIPEACARLEGAFTGQAAEPYKFAVVRSSPNCQPRARFVDAAKARPSEAAGWKFNDVIRVPSAVCPQQQAVVRVWRKPAAVAPPELDAQGRARLYLQDEKARAEAAKLAAVPMFAASMTIEGKACGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCH7</accession>
    <name>A0A0S2DCH7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="GLE_0861"/>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="249" mass="27798" checksum="489DD8134D1031DD" modified="2016-02-17" version="1">MALDPKKIRPFLWLLSLWLQTKKVTRPLADGSSGSSLVFTRTNVQTQTPPRHAPCRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSYSRIRIFTPVIPAKAGTHVDVAAAFAATDVPRDDKPPSKAFVRKRPSYFLLSARQKKVAKEKRFLRSQATRSSTRRGAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCS4</accession>
    <name>A0A0S2DCS4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Ribonucleoside-diphosphate reductase</fullName>
            <ecNumber evidence="4 12">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FE772_05480</name>
        <name evidence="15" type="ORF">GLE_0973</name>
    </gene>
    <organism evidence="15 17">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="15 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="16 18" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <text>[thioredoxin]-disulfide + a 2'-deoxyribonucleoside 5'-diphosphate + H2O = [thioredoxin]-dithiol + a ribonucleoside 5'-diphosphate</text>
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        </reaction>
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        <source>
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    </evidence>
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    </evidence>
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    </evidence>
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</entry>
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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</entry>
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        <source>
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        <source>
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    </evidence>
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        <source>
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        </source>
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</entry>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
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                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 6">B25</strain>
        </source>
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    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
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    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="110" mass="12007" checksum="F866A5F9D5112503" modified="2016-02-17" version="1">MSQDKIFEALASRPRRQILAFLSERELSAGDIAARFDMSAPAVSRHLSVLVNAGLISSERRGQFVVYKLVPDHLVNTLTQFAFEICPVGGPLKRESRRAARKSAGGKPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDX2</accession>
    <name>A0A0S2DDX2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Shikimate kinase</fullName>
            <shortName evidence="10">SK</shortName>
            <ecNumber evidence="3 10">2.7.1.71</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10 12" type="primary">aroK</name>
        <name evidence="12" type="ORF">BV903_16215</name>
        <name evidence="13" type="ORF">FE772_06280</name>
        <name evidence="11" type="ORF">GLE_1151</name>
    </gene>
    <organism evidence="11 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">C3</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">B25</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + shikimate = 3-phosphoshikimate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13121"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.71"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the shikimate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.71" evidence="3 10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000043">
        <property type="protein sequence ID" value="OPD62828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946556.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1151"/>
    <dbReference type="EnsemblBacteria" id="ALN56509">
        <property type="protein sequence ID" value="ALN56509"/>
        <property type="gene ID" value="GLE_1151"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62828">
        <property type="protein sequence ID" value="OPD62828"/>
        <property type="gene ID" value="BV903_16215"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1151"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1136"/>
    <dbReference type="OMA" id="IGKHLFE"/>
    <dbReference type="OrthoDB" id="1392851at2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00088"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004765">
        <property type="term" value="F:shikimate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00464">
        <property type="entry name" value="SK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00109">
        <property type="entry name" value="Shikimate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031322">
        <property type="entry name" value="Shikimate/glucono_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000623">
        <property type="entry name" value="Shikimate_kinase/TSH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023000">
        <property type="entry name" value="Shikimate_kinase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01202">
        <property type="entry name" value="SKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01128">
        <property type="entry name" value="SHIKIMATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="14"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN56509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OPD62828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW25327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="188" mass="20070" checksum="7E453FD5E838CCAF" modified="2016-02-17" version="1">MNPASNLILVGPMGSGKTCIGKRLAERFGLRAVDADREVELRAGARIAEIFEHEGEAGFRARETATLAELLAGDGLLLSTGGGAVLAADNRRLLRERGFVVYLQVSVEQQLERLAQDRSRPLLARGDREQVLRDLARVRAPLYAEVADLPFDTGAAGAGEAALGLARQLDALWRRPPSSTSSPLGATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDX3</accession>
    <name>A0A0S2DDX3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acyl-peptide hydrolase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Acylaminoacyl-peptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLE_1470</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S9C family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946801.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1470"/>
    <dbReference type="EnsemblBacteria" id="ALN56827">
        <property type="protein sequence ID" value="ALN56827"/>
        <property type="gene ID" value="GLE_1470"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1470"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1451"/>
    <dbReference type="OrthoDB" id="821953at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002471">
        <property type="entry name" value="Pept_S9_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002469">
        <property type="entry name" value="Peptidase_S9B_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00930">
        <property type="entry name" value="DPPIV_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00708">
        <property type="entry name" value="PRO_ENDOPEP_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0007">Acetylation</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594997" description="Acyl-peptide hydrolase" evidence="8">
        <location>
            <begin position="28"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="domain" description="DPPIV_N" evidence="10">
        <location>
            <begin position="275"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="9">
        <location>
            <begin position="502"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN56827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="708" mass="76492" checksum="16379F2827D367A0" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDY9</accession>
    <name>A0A0S2DDY9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">PPE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_06365</name>
        <name evidence="1" type="ORF">GLE_1167</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946568.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56525">
        <property type="protein sequence ID" value="ALN56525"/>
        <property type="gene ID" value="GLE_1167"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1167"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1152"/>
    <dbReference type="OrthoDB" id="2113627at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="227" mass="22821" checksum="25D872F4EF3ACC07" modified="2016-02-17" version="1">MDTTPSLSSVQTLGGVPTAATYADVAQAIPTAAAVTEYNAWAASFSITPNDPATVETAPLSAFSFNLGLNHVGDINASIEARMGIAPAQVTFAGKVSYTDGITGYSLSGVAGPLGGVADPNYGLTAELSKQLDFGKLEASLNLNANPDGFTNGRVATGVTAPLSDNWNGYARVGVGFDRNGVTSVDGTIGADYSAGGASLGVSDSGRVDTRTGDVSGGAKFNLGIKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDZ4</accession>
    <name>A0A0S2DDZ4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">VOC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_07280</name>
        <name evidence="2" type="ORF">GLE_1373</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946725.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1373"/>
    <dbReference type="EnsemblBacteria" id="ALN56730">
        <property type="protein sequence ID" value="ALN56730"/>
        <property type="gene ID" value="GLE_1373"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1373"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1355"/>
    <dbReference type="OMA" id="YELAVWT"/>
    <dbReference type="OrthoDB" id="1864858at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="9"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="116" mass="12797" checksum="8ECBBBD97F8F02EE" modified="2016-02-17" version="1">MSATDRNLRLDYLEFNVADIAASKAFYGAAFGWRFTDYGPDYCEFDDGRLKGGFSTHAAPRPGGALVVIYADDLADARRRVEAAGGAIVAEHEFPGGRRFHFLDPDGYELAVWTQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE28</accession>
    <name>A0A0S2DE28_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_07310</name>
        <name evidence="2" type="ORF">GLE_1379</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946731.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1379"/>
    <dbReference type="EnsemblBacteria" id="ALN56736">
        <property type="protein sequence ID" value="ALN56736"/>
        <property type="gene ID" value="GLE_1379"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1379"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1361"/>
    <dbReference type="OrthoDB" id="2055010at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008125">
        <property type="entry name" value="Streptothricin_AcTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01754">
        <property type="entry name" value="SACTRNSFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="51"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="205" mass="23177" checksum="A627EAAAE9954E9B" modified="2016-02-17" version="1">MSAGEQDSDAQDEARGPTVHALREQDVDAAVAFDGSFIAFQRLLLQLRDGALWCDLDSFETERLEEPYRKNYGDDADAEGLRDYLQRARGNTATDAAAFVVRLDGRVAGRMMMSRTWNGFAYIDDIAIDRNARRRGAGTALMHAALDWARTHGYPGIMLETQDTNVIACRMYLRHGFVLGGCDRYHYANEPDIAHETALFWYRML</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE94</accession>
    <name>A0A0S2DE94_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56782">
        <property type="protein sequence ID" value="ALN56782"/>
        <property type="gene ID" value="GLE_1425"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1425"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1405"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="74" mass="7990" checksum="AF95BE61E757AEA6" modified="2016-02-17" version="1">MGHGSFLQDVGEGRRSEGQSAKKKPARDGARPPTLRAAQRGRWEGRETNAAQAAGRPPRGSVERVGRLGRRSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEK2</accession>
    <name>A0A0S2DEK2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA polymerase sigma factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_1599</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1599"/>
    <dbReference type="EnsemblBacteria" id="ALN56956">
        <property type="protein sequence ID" value="ALN56956"/>
        <property type="gene ID" value="GLE_1599"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1599"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1579"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
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        <property type="entry name" value="WH-like_DNA-bd_sf"/>
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        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
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    <dbReference type="PROSITE" id="PS01063">
        <property type="entry name" value="SIGMA70_ECF"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="281"/>
            <end position="303"/>
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    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="315"/>
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    <feature type="transmembrane region" description="Helical" evidence="4">
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            <begin position="343"/>
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    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="398"/>
            <end position="415"/>
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    <feature type="domain" description="Sigma70_r2" evidence="5">
        <location>
            <begin position="31"/>
            <end position="95"/>
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    <feature type="domain" description="Sigma70_r4_2" evidence="6">
        <location>
            <begin position="132"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
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    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000716"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
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        <source>
            <dbReference type="Pfam" id="PF04542"/>
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        <source>
            <dbReference type="Pfam" id="PF08281"/>
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        <source>
            <dbReference type="EMBL" id="ALN56956.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="421" mass="44185" checksum="44A3F17F735290C0" modified="2016-02-17" version="1">MNAQALDSLIGHDLPLAAGGDSAAYSRIVGACQNSVTAIALAMVRDVQASEDIAQEAFLSAWQNIRKLHNPSSFLPWLRQITRNLARDHLRARVRQPRAVEDAELAIELAADPAPGAIETLLEAERARVAAELISALPDESREVLLLYYREGQSSQQVAALLGLSDAAVRKRLSRARGAVREELMERFAAFARASAPSVGFTTLVASSLGLIAPPSIAAAALAGGAAGSSVAGKFGLGASSASGGVAGGGAAALLDRLLAPFAAAGGGEALEHGARWSVQLGGVIGGTIGGALGALAMTQILLRYARGAQERRRIYRMMIAMSVSAALVCLGLLAALALSRGWLAPAAFLLLSMALMNWQMLRWLPREIGPLLDRAQRESGRDPRAGFGYRWLLGKPAIVWSNVALLASIALVLYKDGRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEQ5</accession>
    <name>A0A0S2DEQ5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CTP synthase</fullName>
            <ecNumber evidence="9">6.3.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cytidine 5'-triphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Cytidine triphosphate synthetase</fullName>
            <shortName evidence="9">CTP synthetase</shortName>
            <shortName evidence="9">CTPS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">UTP--ammonia ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 12" type="primary">pyrG</name>
        <name evidence="13" type="ORF">FE772_07790</name>
        <name evidence="12" type="ORF">GLE_1483</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">C3</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + H2O + L-glutamine + UTP = ADP + CTP + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:26426"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + NH4(+) + UTP = ADP + CTP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16597"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="9">CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the CTP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.2" evidence="9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946812.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1483"/>
    <dbReference type="EnsemblBacteria" id="ALN56840">
        <property type="protein sequence ID" value="ALN56840"/>
        <property type="gene ID" value="GLE_1483"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1483"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1464"/>
    <dbReference type="OMA" id="EFNNAYR"/>
    <dbReference type="OrthoDB" id="783657at2"/>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00277"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003883">
        <property type="term" value="F:CTP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03113">
        <property type="entry name" value="CTPS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01746">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01227">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004468">
        <property type="entry name" value="CTP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017456">
        <property type="entry name" value="CTP_synthase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033828">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550">
        <property type="entry name" value="PTHR11550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06418">
        <property type="entry name" value="CTP_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00337">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4 9 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CTP_synth_N" evidence="11">
        <location>
            <begin position="5"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="GATase" evidence="10">
        <location>
            <begin position="301"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Amidoligase domain" evidence="9">
        <location>
            <begin position="1"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="L-glutamine binding" evidence="9">
        <location>
            <begin position="379"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for glutamine hydrolysis" evidence="9">
        <location>
            <position position="378"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="516"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="518"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="14"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="146"/>
            <end position="148"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="186"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="351"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="402"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="469"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN56840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW25582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="552" mass="61129" checksum="CC428F0835BC23BF" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF95</accession>
    <name>A0A0S2DF95_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57241">
        <property type="protein sequence ID" value="ALN57241"/>
        <property type="gene ID" value="GLE_1890"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1890"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1859"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="93" mass="9873" checksum="DFF4ABB5C56DAF66" modified="2016-02-17" version="1">MAREGRPGSAPARAAPARAAGLAGMALSLAIAGRPVGSGRPSARLRARRPRPPGFADAATSPPRRGFAPIRDRRRKRNEIFLSSPLARPGERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFA0</accession>
    <name>A0A0S2DFA0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Histidine biosynthesis bifunctional protein HisIE</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="13">Phosphoribosyl-AMP cyclohydrolase</fullName>
                <shortName evidence="13">PRA-CH</shortName>
                <ecNumber evidence="13">3.5.4.19</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="13">Phosphoribosyl-ATP pyrophosphatase</fullName>
                <shortName evidence="13">PRA-PH</shortName>
                <ecNumber evidence="13">3.6.1.31</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="13 15" type="primary">hisI</name>
        <name evidence="13" type="synonym">hisIE</name>
        <name evidence="16" type="ORF">FE772_09730</name>
        <name evidence="15" type="ORF">GLE_1904</name>
    </gene>
    <organism evidence="15 17">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="15 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">C3</strain>
        </source>
    </reference>
    <reference evidence="16 18" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O = 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:20049"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="EC" id="3.5.4.19"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 13">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + H2O = 1-(5-phospho-beta-D-ribosyl)-5'-AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22828"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="3.6.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 13">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 13">In the C-terminal section; belongs to the PRA-PH family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 13">In the N-terminal section; belongs to the PRA-CH family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.19" evidence="13"/>
    <dbReference type="EC" id="3.6.1.31" evidence="13"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947132.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1904"/>
    <dbReference type="EnsemblBacteria" id="ALN57255">
        <property type="protein sequence ID" value="ALN57255"/>
        <property type="gene ID" value="GLE_1904"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1904"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1872"/>
    <dbReference type="OMA" id="ERSCFHQ"/>
    <dbReference type="OrthoDB" id="1842189at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004635">
        <property type="term" value="F:phosphoribosyl-AMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004636">
        <property type="term" value="F:phosphoribosyl-ATP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11534">
        <property type="entry name" value="NTP-PPase_HisIE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01020">
        <property type="entry name" value="HisE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01019">
        <property type="entry name" value="HisIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023019">
        <property type="entry name" value="His_synth_HisIE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008179">
        <property type="entry name" value="HisE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021130">
        <property type="entry name" value="PRib-ATP_PPHydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002496">
        <property type="entry name" value="PRib_AMP_CycHydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038019">
        <property type="entry name" value="PRib_AMP_CycHydrolase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01502">
        <property type="entry name" value="PRA-CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01503">
        <property type="entry name" value="PRA-PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141734">
        <property type="entry name" value="SSF141734"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03188">
        <property type="entry name" value="histidine_hisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 13" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="9 13 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 13" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRA-CH" evidence="14">
        <location>
            <begin position="36"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosyl-AMP cyclohydrolase" evidence="13">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosyl-ATP pyrophosphohydrolase" evidence="13">
        <location>
            <begin position="119"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00008299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ALN57255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QCW25902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="217" mass="23366" checksum="C704761803BEE3AA" modified="2016-02-17" version="1">MDATLSPRQIDALDWDKQDGLLPAVVQDAANLRVLMLGYMDRAALDATLASGHVTFFSRSKQRLWTKGESSGHFLDLVSIETDCDRDTLLVRALPHGPTCHLGRDSCFPSAPGDGLAFLAELDALVATRERERPAGSYTTGLFERGVRAIAQKVGEEGVETALAAVAQDEAALAGEAADLLFHLQVLLRARGLSLSDAVAVLQQRHGKPHRGFKPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFH4</accession>
    <name>A0A0S2DFH4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">VOC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_10070</name>
        <name evidence="2" type="ORF">GLE_1982</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947187.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1982"/>
    <dbReference type="EnsemblBacteria" id="ALN57332">
        <property type="protein sequence ID" value="ALN57332"/>
        <property type="gene ID" value="GLE_1982"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1982"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1947"/>
    <dbReference type="OMA" id="IGMHRVA"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="5"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="147" mass="16271" checksum="669C3A3CB305D3E5" modified="2016-02-17" version="1">MALKRMDNVGIVVEDLGAAIEFFRELGLELEGRATVEGEWAGRVTGLGDQRVEIAMMRTPDGHSRLELSRFIEPKVIADHRNAPVNALGYLRVMFAVDDLADTLERLRPHGAQVVGEVVDYQNVYRLCYIRGPEGILIGLAQELAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFJ0</accession>
    <name>A0A0S2DFJ0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1999</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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    </evidence>
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</entry>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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    <evidence type="ECO:0000256" key="1">
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    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="113" mass="12056" checksum="27481C05A97F57E0" modified="2016-02-17" version="1">MEQAVLIFGVLLALGWNALLLYWSRGYLRYAAVAMFALNLLIGSPLFGVIGWNLASQDVDTNYVEGYGDVLVAVIVGLANGVVALVGAIVVALRKAPAAAAEDARKDRRDPPR</sequence>
</entry>
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            <strain evidence="7 9">C3</strain>
        </source>
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    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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    <dbReference type="EnsemblBacteria" id="ALN57420">
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        <source>
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    </evidence>
    <sequence length="426" mass="45575" checksum="E0E1006FB7463173" modified="2016-02-17" version="1">MSAAAPATVNSPSRVLFASLIGTTIEFFDFYIYATAAVLVFPQLFFPSADPNTAQLQSLAAFALAFFARPIGAALFGHFGDRIGRKATLVAALLTMGLSTVIIGLLPTYQSIGIVAPIALALCRFGQGLGLGGEWGGAVLLATENAPPGKRAWYGMFPQLGAPIGFFLSTGIFLLLTDLMGDEAFFAWGWRVPFWSSAALVFVGLWVRLSISETPAFRKAMDHHERVKVPMLNVLLKHPGALVAGTFAALATFVLFYLMTVFALGWGTSHLGYTRHQFLLLQLGSVLCFAATIPLSAVFADRKGRRLAMIVSTLAVMLFGVLFERLFVAGNPWGVFAFLSLGLGVMGLTYGPLGTILAEMFPTAVRYTGASLAFNFAGILGASLAPSIAMFLAERYSLAYVGYYLAAAGALTLIALLMMREDEPAR</sequence>
</entry>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <location>
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            <end position="35"/>
        </location>
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            <end position="253"/>
        </location>
    </feature>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN57410.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="253" mass="28757" checksum="C8B580EFA7E3DF7C" modified="2016-02-17" version="1">MTSSRRAAVSRPPHRRWHRIALCAALLAAAPLAQAQLVVTDPGNLGVAIKDFIDKAFQYGEQAKRWTSQYSHYRQQLIKLQQLQMQQSAMRDDFPERDPSYGMDDICPGPRSEGLSGAMSAFNPRLDSDLVAEQRRLCQRMVLADNAKYNESVRMLKQLLQRNREFSQVEGQRGQVGDSQGSLAANDNETQRFMVRTRMDLDYWQARMKAYDDYIVALQKDQARLARRALEGKRPGGVGKIIQTEAIKSAFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFZ1</accession>
    <name>A0A0S2DFZ1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha-1,2-mannosidase</fullName>
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    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1872</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR005887">
        <property type="entry name" value="Alpha_mannosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041371">
        <property type="entry name" value="GH92_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012939">
        <property type="entry name" value="Glyco_hydro_92"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07971">
        <property type="entry name" value="Glyco_hydro_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17678">
        <property type="entry name" value="Glyco_hydro_92N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01180">
        <property type="entry name" value="aman2_put"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_92N" evidence="2">
        <location>
            <begin position="290"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_92" evidence="1">
        <location>
            <begin position="521"/>
            <end position="1028"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1187" mass="130573" checksum="6DF265AB113EA8E1" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG15</accession>
    <name>A0A0S2DG15_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57505">
        <property type="protein sequence ID" value="ALN57505"/>
        <property type="gene ID" value="GLE_2155"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2155"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2118"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="131" mass="13680" checksum="0DBF081BAE6A0A95" modified="2016-02-17" version="1">MGDGWIVGAAPSRASIRGGADGFRANAGPTRTGECGPVASRGWRAVRRWAPLAGGHPRKRRGRGGQDRPGPWTGAAPMLSQQGLGRLWRRRGKGFGRKAGVDAGEKCCAGATAAEGEWAAQAGFLGRFARQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG86</accession>
    <name>A0A0S2DG86_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SCO family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">SCO1/SenC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_10795</name>
        <name evidence="4" type="ORF">GLE_2138</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SCO1/2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947308.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2138"/>
    <dbReference type="EnsemblBacteria" id="ALN57488">
        <property type="protein sequence ID" value="ALN57488"/>
        <property type="gene ID" value="GLE_2138"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2138"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2102"/>
    <dbReference type="OMA" id="GELKGHW"/>
    <dbReference type="OrthoDB" id="1994201at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd02968">
        <property type="entry name" value="SCO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003782">
        <property type="entry name" value="SCO1/SenC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12151">
        <property type="entry name" value="PTHR12151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02630">
        <property type="entry name" value="SCO1-SenC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="44"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="214" mass="23018" checksum="622FE0154D1924F2" modified="2016-02-17" version="1">MFNRTTAIVLVAALAAALGLWASQKYFGSAKRSHLPQTQAVRLFDPPRTLPAFSLRQSDGTPLIPGELKGHWTLVFLGFTHCPDVCPTTLAQMSVAQKAWEAIPESTRPRVLFVSVDPERDSPDKIGEYAHGFHKDTLAATADVPALENFAKSLSMVFAKVPAPPGAPANQYSMDHSASMAVLDPQGRMAGLVRPPFDPNAIARDMAALTEASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-08-12" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGU0</accession>
    <name>A0A0S2DGU0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aha1 domain protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">SRPBCC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_10715</name>
        <name evidence="2" type="ORF">GLE_2121</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947295.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57471">
        <property type="protein sequence ID" value="ALN57471"/>
        <property type="gene ID" value="GLE_2121"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2121"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2085"/>
    <dbReference type="OMA" id="AGGWHTH"/>
    <dbReference type="OrthoDB" id="1498264at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013538">
        <property type="entry name" value="Activator_of_Hsp90_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08327">
        <property type="entry name" value="AHSA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="183" mass="20675" checksum="9A4C5FC08053EE0E" modified="2016-02-17" version="1">MNLPANDAYGVLTAADSVRIERVLPGPIERVWAYLTESDKRRHWLAAGEMDLRVGGAVELNFDNARLTRNDDPPPAKYASDCVNTLRGRITAIEPPRLLRYTWNEDAGSKSEVSFELSEQGEQVRLVVHHRHLSDRSGLVSVSGGWHAHLGLLIDVLSQREPEGFWRSHSRLDAEYERRIPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGU9</accession>
    <name>A0A0S2DGU9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Outer membrane protein assembly factor BamE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 9" type="primary">bamE</name>
        <name evidence="7" type="ORF">BV903_23060</name>
        <name evidence="9" type="ORF">D9T17_13585</name>
        <name evidence="8" type="ORF">FE772_11225</name>
        <name evidence="6" type="ORF">GLE_2227</name>
    </gene>
    <organism evidence="6 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 10">C3</strain>
        </source>
    </reference>
    <reference evidence="7 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">OH11</strain>
        </source>
    </reference>
    <reference evidence="8 13" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the Bam complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the BamE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000078">
        <property type="protein sequence ID" value="OPD61544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000033">
        <property type="protein sequence ID" value="ROU06478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947379.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2227"/>
    <dbReference type="EnsemblBacteria" id="ALN57576">
        <property type="protein sequence ID" value="ALN57576"/>
        <property type="gene ID" value="GLE_2227"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61544">
        <property type="protein sequence ID" value="OPD61544"/>
        <property type="gene ID" value="BV903_23060"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2227"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2192"/>
    <dbReference type="OMA" id="HYPSRFA"/>
    <dbReference type="OrthoDB" id="1813418at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051205">
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="BamE"/>
    </dbReference>
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        <property type="entry name" value="BamE-like"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="SmpA_OmlA" evidence="5">
        <location>
            <begin position="28"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00925"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF04355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD61544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW26156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROU06478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="131" mass="15064" checksum="2943F03650F7CC6A" modified="2016-02-17" version="1">MRKLLLVLSLALVTSGCGIIYKQPIYQGNLLEKTAVDQLQAGMSKQQVQVLIGTPSIEDPFHQNRWDYTSTQRVDRLGHTARKNLTLWFENDALTKWEGDYFPEQDKEIAAASVKQFGRNLAKEKDKKKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGY6</accession>
    <name>A0A0S2DGY6_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">Peptidase, M28 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2562</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2562"/>
    <dbReference type="EnsemblBacteria" id="ALN57911">
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    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2562"/>
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    <dbReference type="OMA" id="FAFIDDH"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
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        </location>
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        </location>
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            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="552"/>
        </location>
    </feature>
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            <begin position="94"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57911.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="757" mass="79740" checksum="75251918F60A0BEC" modified="2016-02-17" version="1"> </sequence>
</entry>
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    <accession>A0A0S2DH85</accession>
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    <protein>
        <submittedName>
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
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    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="528" mass="58779" checksum="5688E34DA11B0901" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHB0</accession>
    <name>A0A0S2DHB0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Biliverdin-producing heme oxygenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Heme oxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_12125</name>
        <name evidence="1" type="ORF">GLE_2425</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947529.1">
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_2425"/>
    <dbReference type="EnsemblBacteria" id="ALN57774">
        <property type="protein sequence ID" value="ALN57774"/>
        <property type="gene ID" value="GLE_2425"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2425"/>
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    <dbReference type="OMA" id="ITHAPHA"/>
    <dbReference type="OrthoDB" id="1608763at2"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0004392">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="199" mass="21785" checksum="DC3F7DE09A7E7CF9" modified="2016-02-17" version="1">MAAHDLASDFTDLPRSQRLKAATRATHDRLDRRIMAGDIFADRGRFARFVRVQYRFHRDIDALYAHPALDALLPDLAGRRRLDQIASDLRDLGQALPTPAQPKAEAGLPLAQALGWLYVAEGSNLGGSVLYKLAAKLGLDREFGARHLAAHPDGVARHWREFTAALDSAALDAAQERDLVAGAEAAFRSVRGHVEAEFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHC1</accession>
    <name>A0A0S2DHC1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_12225</name>
        <name evidence="1" type="ORF">GLE_2446</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947543.1">
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57795">
        <property type="protein sequence ID" value="ALN57795"/>
        <property type="gene ID" value="GLE_2446"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2446"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2409"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="135" mass="15113" checksum="D9C9998108BB231A" modified="2016-02-17" version="1">MAKVITDEDILSAFHASDPRLWLREHVAGLTRRACYYYEAPISQSDNTIIRHEVLITHADPFAPTARSKVEISSSAVTGGPHFPLFSQEYELEISPAEESVQRGTWSRLDDAMIKKAHDIARAASDYQPEARSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHP3</accession>
    <name>A0A0S2DHP3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2602</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57950">
        <property type="protein sequence ID" value="ALN57950"/>
        <property type="gene ID" value="GLE_2602"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2602"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2562"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="61" mass="7262" checksum="180928F545B5F243" modified="2016-02-17" version="1">MRNRLHSEEFCGFMPAAKLSGWISIRSIDSKHRLPMRIPLRRDASKDLSERPFGYGFRKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI16</accession>
    <name>A0A0S2DI16_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2461 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_13430</name>
        <name evidence="1" type="ORF">GLE_2681</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947731.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2681"/>
    <dbReference type="EnsemblBacteria" id="ALN58029">
        <property type="protein sequence ID" value="ALN58029"/>
        <property type="gene ID" value="GLE_2681"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2681"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2640"/>
    <dbReference type="OMA" id="YKTHQGA"/>
    <dbReference type="OrthoDB" id="1258218at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012808">
        <property type="entry name" value="CHP02453"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015996">
        <property type="entry name" value="UCP028451"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36452">
        <property type="entry name" value="PTHR36452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09365">
        <property type="entry name" value="DUF2461"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028451">
        <property type="entry name" value="UCP028451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02453">
        <property type="entry name" value="TIGR02453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="228" mass="26246" checksum="BC5533343F568120" modified="2016-02-17" version="1">MPSYFSDASFKFLRSLARNNNREWFHAHKAAYDEHVRGPFLRLLGDLQPGLAQVSEHYRSEPRNVGGSLFRIQRDTRFANDKAPYKSWQGARLFHERGRQVEAPSFYIHLAQGECFVAAGVWHPAPETLRKIRHFVFDNPGSWKAAAHDPKFRKRFDLDDSEVLTRAPRGFPPEFEFADDLRRKNFVAYRSLDDAVMTGPRLLSTLEKDLAGLAPFADYLCAALDLEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIC3</accession>
    <name>A0A0S2DIC3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2861</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2861"/>
    <dbReference type="EnsemblBacteria" id="ALN58209">
        <property type="protein sequence ID" value="ALN58209"/>
        <property type="gene ID" value="GLE_2861"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2861"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2823"/>
    <dbReference type="OMA" id="NPEKDWG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047989">
        <property type="term" value="F:hydroxybutyrate-dimer hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019605">
        <property type="term" value="P:butyrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016582">
        <property type="entry name" value="OHBut_olig_hydro_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10605">
        <property type="entry name" value="3HBOH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595631" evidence="2">
        <location>
            <begin position="27"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="653" mass="67728" checksum="1E5E6FE5218CADEE" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIJ8</accession>
    <name>A0A0S2DIJ8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA-specific adenosine deaminase</fullName>
            <ecNumber evidence="3">3.5.4.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">tadA</name>
        <name evidence="5" type="ORF">GLE_2885</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>adenosine(34) in tRNA + H(+) + H2O = inosine(34) in tRNA + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:43168"/>
            <dbReference type="Rhea" id="RHEA-COMP:10373"/>
            <dbReference type="Rhea" id="RHEA-COMP:10374"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:82852"/>
            <dbReference type="EC" id="3.5.4.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.33" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2885"/>
    <dbReference type="EnsemblBacteria" id="ALN58233">
        <property type="protein sequence ID" value="ALN58233"/>
        <property type="gene ID" value="GLE_2885"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2885"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2847"/>
    <dbReference type="OMA" id="LSMSINT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052717">
        <property type="term" value="F:tRNA-specific adenosine-34 deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002100">
        <property type="term" value="P:tRNA wobble adenosine to inosine editing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00972">
        <property type="entry name" value="tRNA_aden_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028883">
        <property type="entry name" value="tRNA_aden_deaminase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="4">
        <location>
            <begin position="7"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="160" mass="17451" checksum="5BFE77459C3025B8" modified="2016-02-17" version="1">MSEQQAEIDRYWMRRALDLAERAEREYDEIPVGAVLVSEAGELLGEGWNRNIGLHDPSAHAEIVAMRDGGQRIGNHRLVGATLYVTLEPCAMCAMAMVHARVARVVFGAFDPKTGAAGSVFDLLADPRHNHRVAVLGGVLGDEAGARLSAYFRRKRGKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIU5</accession>
    <name>A0A0S2DIU5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3089</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58436">
        <property type="protein sequence ID" value="ALN58436"/>
        <property type="gene ID" value="GLE_3089"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3089"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3048"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="51" mass="5178" checksum="85CA1F392073F42C" modified="2016-02-17" version="1">MGPGPAHDERHRPAPARPAARANRQIAHDQPPGPAPTGAVYTPGTSRGSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIW4</accession>
    <name>A0A0S2DIW4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transporter, major facilitator family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3129</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3129"/>
    <dbReference type="EnsemblBacteria" id="ALN58476">
        <property type="protein sequence ID" value="ALN58476"/>
        <property type="gene ID" value="GLE_3129"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3129"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3086"/>
    <dbReference type="OMA" id="WAPLVPY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="310"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="338"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="368"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="394" mass="38910" checksum="4091ED970151F0CF" modified="2016-02-17" version="1">MSDPHSAAASDPAARGGPIGALERLSTRIAFFIAGLAMAGWAPLVPYAKARTGVDEGTLGLLLLALGAGSMTTMPLTGALTARIGCRKVILLASAAVAAALPLLAQLDTVAGMAAALFAFGAAIGAIDVAINIQAVIVEKASGRPLMSGFHGFFSVGGIAGAAVVSALLWLQATPLVAALSVAVLLALLMLAGSRGLLRYGDDGHGGATFVLPHGIVILVGALCFVVFLAEGAMLDWSALLLVAQRGAEARAGGLGYAVFALAMTVGRFSGDRIVQRFGARPVLALGGVCAAAGFALAATLPWIGTTLLGFALVGLGCSNIVPILFTAAGAQKAMPAGAAISAVSTLGYAGILIGPAGIGWIAKISSLPVAFAVLGVGLVAVAASAKLVAARKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIW9</accession>
    <name>A0A0S2DIW9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2 3">Cyclopropane-fatty-acyl-phospholipid synthase</fullName>
            <ecNumber evidence="3">2.1.1.79</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_15450</name>
        <name evidence="2" type="ORF">GLE_3101</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CFA/CMAS family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.79" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948043.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3101"/>
    <dbReference type="EnsemblBacteria" id="ALN58448">
        <property type="protein sequence ID" value="ALN58448"/>
        <property type="gene ID" value="GLE_3101"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3101"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3059"/>
    <dbReference type="OMA" id="LHCITAQ"/>
    <dbReference type="OrthoDB" id="1518440at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008825">
        <property type="term" value="F:cyclopropane-fatty-acyl-phospholipid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003333">
        <property type="entry name" value="Mycolic_cyclopropane_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003085">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="381" mass="43748" checksum="9DC07823B229BDD1" modified="2016-02-17" version="1">MSLASLHKRVEGLLEQADVRVGGDRPWDLQVEDESFYSRVIAQGSLGLGETYMDGAWHARSLDGLLERLMRARIDEQVHGWAAILDGLRAHLINLQSHRRSFTVGERHYDLGNDLYRAMLGKRLVYSCGYWRDRNGQALHDLDSAQEAKLDLVCRKLRLKPGMRVLDIGCGWGEALKFAAERYGIVGVGVTVSHEQAEFARELCRGLPVEIRLQDYRELDQRFDRIFSLGMFEHVGVRNYAAYFDVARRCLDRASDDGGLFLLHSIGGNKSVSHTDPWIAKYIFPNSMLPSARQIAEHAEDRFVIEDWHNFGADYDLTLQAWRDNVEAAWDRLDARYDERFRRMWRFYLAASMATFRTRHAQLWQLVLSPDGVPGGYVAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ00</accession>
    <name>A0A0S2DJ00_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948083.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58500">
        <property type="protein sequence ID" value="ALN58500"/>
        <property type="gene ID" value="GLE_3154"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3154"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3111"/>
    <dbReference type="OrthoDB" id="1911651at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595668" evidence="1">
        <location>
            <begin position="25"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="103" mass="11104" checksum="08610590900ABA9E" modified="2016-02-17" version="1">MHRPLTAALLAFALAAGVAAPARAGLFDKNPDQVAQDAVTKDLRAVTLWVDASWGFRNQGAANALSRAHQAFVSRGYDVVSVEPYIENGDLQGFFVTYQKPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ26</accession>
    <name>A0A0S2DJ26_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_15740</name>
        <name evidence="1" type="ORF">GLE_3166</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948092.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58512">
        <property type="protein sequence ID" value="ALN58512"/>
        <property type="gene ID" value="GLE_3166"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3166"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3122"/>
    <dbReference type="OrthoDB" id="2096771at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="136" mass="15313" checksum="69462B37BE2104AD" modified="2016-02-17" version="1">MSADDTGPTDAADDADLIAAIRRRLSDRGSLWINQRYSHEGEPAQREYFLKPARRGDIDGANLDSAILDGTILHGTILHGTILLGFDDWQDRHEDAVDLYLSHRRLSFDTLAQALAYTFAQLPLRPEELRAAARRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ40</accession>
    <name>A0A0S2DJ40_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">kdpD</name>
        <name evidence="10" type="ORF">GLE_3196</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948116.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3196"/>
    <dbReference type="EnsemblBacteria" id="ALN58542">
        <property type="protein sequence ID" value="ALN58542"/>
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    <dbReference type="PATRIC" id="fig|69.6.peg.3151"/>
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        <property type="entry name" value="HATPase_C_sf"/>
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        <property type="entry name" value="KdpD_TM"/>
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        <property type="entry name" value="P-loop_NTPase"/>
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        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="KdpD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
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    </dbReference>
    <dbReference type="SMART" id="SM00388">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
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    </dbReference>
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    <keyword evidence="6 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="393"/>
            <end position="413"/>
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            <begin position="444"/>
            <end position="461"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="467"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="9">
        <location>
            <begin position="667"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="874"/>
            <end position="906"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN58542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="906" mass="98389" checksum="D62F4AA924331FD1" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJC7</accession>
    <name>A0A0S2DJC7_LYSEN</name>
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        <submittedName>
            <fullName evidence="9">DNA internalization-related competence protein ComEC/Rec2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLE_3036</name>
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    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58383.1"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_3036"/>
    <dbReference type="EnsemblBacteria" id="ALN58383">
        <property type="protein sequence ID" value="ALN58383"/>
        <property type="gene ID" value="GLE_3036"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3036"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00361">
        <property type="entry name" value="ComEC_Rec2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="283"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="327"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="380"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="8">
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            <end position="726"/>
        </location>
    </feature>
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            <begin position="764"/>
            <end position="801"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN58383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="801" mass="85569" checksum="91ABD4BC783749A6" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJJ6</accession>
    <name>A0A0S2DJJ6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58577">
        <property type="protein sequence ID" value="ALN58577"/>
        <property type="gene ID" value="GLE_3231"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3231"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="96" mass="9872" checksum="16C7184E4207485A" modified="2016-02-17" version="1">MRLYAPIMKQTASPTAPGAGATRTGRADPMRDSTMADRRRVLALAAPARAHAPAGAAVRAAARGPLPGSPRPAATLARCVDSRVRCSVRAIAIAKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJP5</accession>
    <name>A0A0S2DJP5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Methionine aminopeptidase</fullName>
            <shortName evidence="2">MAP</shortName>
            <shortName evidence="2">MetAP</shortName>
            <ecNumber evidence="2 3">3.4.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Peptidase M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 5" type="primary">map</name>
        <name evidence="6" type="ORF">BV903_25375</name>
        <name evidence="7" type="ORF">FE772_16590</name>
        <name evidence="5" type="ORF">GLE_3360</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 2">Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2 3">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="2 3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000114">
        <property type="protein sequence ID" value="OPD61111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948237.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000114.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3360"/>
    <dbReference type="EnsemblBacteria" id="ALN58706">
        <property type="protein sequence ID" value="ALN58706"/>
        <property type="gene ID" value="GLE_3360"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61111">
        <property type="protein sequence ID" value="OPD61111"/>
        <property type="gene ID" value="BV903_25375"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3360"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3310"/>
    <dbReference type="OMA" id="GDHAYTF"/>
    <dbReference type="OrthoDB" id="1285136at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070084">
        <property type="term" value="P:protein initiator methionine removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01086">
        <property type="entry name" value="MetAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01974">
        <property type="entry name" value="MetAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002467">
        <property type="entry name" value="Pept_M24A_MAP1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00500">
        <property type="entry name" value="met_pdase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00680">
        <property type="entry name" value="MAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M24" evidence="4">
        <location>
            <begin position="12"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD61111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW27017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="258" mass="28432" checksum="3BBFA31B816A7D1F" modified="2016-02-17" version="1">MAISIKTPEEIEKMRVAGRLAAEVLQVVAPYVKPGVSTGELDRICYDHIVNVQKAIPANVGYKGFPKTVCTSVNNVICHGIPSDSKILKDGDIVNIDVTVIKDGWHGDTSRMYYAGTPSVMAKRLVEVTREAMFRAIRLVKPGATLGDIGHIIQTYAEAERFSVVRDYCGHGIGRVYHEEPQVLHVGRPGEGIKLVPGMTFTIEPMINEGTYRHKTLPDGWTVVTKDRKLSAQWEHTVAVTEDGVEILTRVPGDDNDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJS9</accession>
    <name>A0A0S2DJS9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Adenylate/guanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3547</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3547"/>
    <dbReference type="EnsemblBacteria" id="ALN58891">
        <property type="protein sequence ID" value="ALN58891"/>
        <property type="gene ID" value="GLE_3547"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3547"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3491"/>
    <dbReference type="OMA" id="FEGREYQ"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="1">
        <location>
            <begin position="25"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="310" mass="33534" checksum="FD37C2FDD164D7D6" modified="2016-02-17" version="1">MPARLIVYPPEAAAISRWIPAGSRLRIGRDPACELRIDHPSVSRQHAELTHGADGWRLLDSGSKNGSHVDGIQVAQAVLERSEAWLRFGDVLCEFSLHDEAEAQAWQERERERRALSQAWTRRLEVGAAPPAEAAMAGDFDDAAAAADLPGDILRGVVELAGCSRGFLLLAQGEDFLVQASLSLEHEDLNARAFSGSVGAVQRSLRERQPVVVNWIDDDPWLAQRSSVVTGGLQSLVCLPLLHAGRVLGAVYADRRGAGEAISQFDMELLAAFADSAALWLLAQRAFEALQPPAAPLRWTRVLGAQATSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK28</accession>
    <name>A0A0S2DK28_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosome maturation factor RimM</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 5" type="primary">rimM</name>
        <name evidence="6" type="ORF">BV903_24625</name>
        <name evidence="7" type="ORF">FE772_16120</name>
        <name evidence="5" type="ORF">GLE_3254</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Binds ribosomal protein S19.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="2">The PRC barrel domain binds ribosomal protein S19.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RimM family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000096">
        <property type="protein sequence ID" value="OPD61261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948154.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000096.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3254"/>
    <dbReference type="EnsemblBacteria" id="ALN58600">
        <property type="protein sequence ID" value="ALN58600"/>
        <property type="gene ID" value="GLE_3254"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61261">
        <property type="protein sequence ID" value="OPD61261"/>
        <property type="gene ID" value="BV903_24625"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3254"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3208"/>
    <dbReference type="OMA" id="ITVDWEA"/>
    <dbReference type="OrthoDB" id="1497415at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00014">
        <property type="entry name" value="Ribosome_mat_RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011961">
        <property type="entry name" value="16S_RimM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027275">
        <property type="entry name" value="PRC-brl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002676">
        <property type="entry name" value="RimM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036976">
        <property type="entry name" value="RimM_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05239">
        <property type="entry name" value="PRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01782">
        <property type="entry name" value="RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02273">
        <property type="entry name" value="16S_RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="RimM" evidence="3">
        <location>
            <begin position="10"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="PRC" evidence="4">
        <location>
            <begin position="98"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD61261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW26934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="171" mass="19226" checksum="B0ADF2E090E7CF40" modified="2016-02-17" version="1">MSESSRRILLGRVLGAFGIRGEAKLESWTEPRAAIFRYQPWIVRDPHGGERELSGVRGRESGKYLIANLPGVTDRDAVEALRGTEIYVPRSALPPPREGEFYWVDLEGLDVVTTQGLALGKVSHLFATGANDVLVARDDERERMIPFVIPQYVLSVDFEARRVTVDWDPDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKG3</accession>
    <name>A0A0S2DKG3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Type-4 uracil-DNA glycosylase</fullName>
            <ecNumber evidence="3">3.2.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLE_3706</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.</text>
            <dbReference type="EC" id="3.2.2.27"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.27" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3706"/>
    <dbReference type="EnsemblBacteria" id="ALN59050">
        <property type="protein sequence ID" value="ALN59050"/>
        <property type="gene ID" value="GLE_3706"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3706"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3650"/>
    <dbReference type="OMA" id="TPERGHI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005273">
        <property type="entry name" value="Ura-DNA_glyco_family4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03914">
        <property type="entry name" value="UDG_fam_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="9">
        <location>
            <begin position="41"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="209" mass="23488" checksum="9AF8FC10F7AFE32D" modified="2016-02-17" version="1">MPPFAKPTKAPVPRASLRALRAHAAQCRACPLWREATATVFGEGPARARAMLIGEQPGDEEDRSGRPFVGPAGRLLDRALADAGLDRKTLYLTNAVKHFKFQRRGKRRMHDRANAHEQEACRIWLAAEWLRLKPRWALALGAMAAQTLFGAAFRLSRERGCWIALDARTRAMASWHPSAILRSPSSVREQRYCELVVDLRRLAQALDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKL4</accession>
    <name>A0A0S2DKL4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Phenylalanine--tRNA ligase alpha subunit</fullName>
            <ecNumber evidence="13">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Phenylalanyl-tRNA synthetase alpha subunit</fullName>
            <shortName evidence="13">PheRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 15" type="primary">pheS</name>
        <name evidence="16" type="ORF">FE772_17560</name>
        <name evidence="15" type="ORF">GLE_3565</name>
    </gene>
    <organism evidence="15 17">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="15 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">C3</strain>
        </source>
    </reference>
    <reference evidence="16 18" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Binds 2 magnesium ions per tetramer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 13">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="13"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948385.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3565"/>
    <dbReference type="EnsemblBacteria" id="ALN58909">
        <property type="protein sequence ID" value="ALN58909"/>
        <property type="gene ID" value="GLE_3565"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3565"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3509"/>
    <dbReference type="OMA" id="DWHNFTA"/>
    <dbReference type="OrthoDB" id="469058at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00281">
        <property type="entry name" value="Phe_tRNA_synth_alpha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004529">
        <property type="entry name" value="Phe-tRNA-synth_IIc_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004530">
        <property type="entry name" value="Phe-tRNA-synth_IIc_mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004188">
        <property type="entry name" value="Phe-tRNA_ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022911">
        <property type="entry name" value="Phe_tRNA_ligase_alpha1_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002319">
        <property type="entry name" value="Phenylalanyl-tRNA_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF41">
        <property type="entry name" value="PTHR11538:SF41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02912">
        <property type="entry name" value="Phe_tRNA-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01409">
        <property type="entry name" value="tRNA-synt_2d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00468">
        <property type="entry name" value="pheS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 13 15" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="10 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="14">
        <location>
            <begin position="118"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ALN58909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QCW27170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="341" mass="37883" checksum="48F7D424FDA507EB" modified="2016-02-17" version="1">MAQIEQLTQHALAEIAAADSPEAIEALRVSLLGKSGSVTAQLKQLGALPADERKAAGEAINKARDALTDALARRKSALDDAALDARLAAETIDVTLPGIDAARGGLHPVSRTMERMADIFGRLGFELADGPEIEDDWHNFEALNFPPHHPARAMHDTFYFPPDSAGVARLLRTHTSGMQVRYMLQAVADKSGPPLRMIALGKVYRSDSDQTHTPMFHQCEGLLIDEHSSFADLKGTLAEFVRAFFERDFEMRFRPSYFPFTEPSAEVDIAWQQADGSTRWLEVLGCGMVHPNVLRNVGIDPERYTGYAFGMGVERLTMLRYGVDDLRSFFENDVRFLRQFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKQ7</accession>
    <name>A0A0S2DKQ7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948363.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3535"/>
    <dbReference type="EnsemblBacteria" id="ALN58879">
        <property type="protein sequence ID" value="ALN58879"/>
        <property type="gene ID" value="GLE_3535"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3535"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3479"/>
    <dbReference type="OMA" id="LAWIETK"/>
    <dbReference type="OrthoDB" id="1216348at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="434" mass="46092" checksum="67F8A012473D5BC4" modified="2016-02-17" version="1">MAAAETTAPPARRSRKRLWIVLALLLAALLGLRWVSRPSQVGWIVLSQAGRALGLEISAGGASEYRLRGTPMLEVRDLVARVPGSDKPLLRAGRVYLAVPWTTIRAAGASLDVERIELDAPQLDIGELQRWLASRPASTEPFDIPRLSRGARVRDGRVAAAGWSVQGIGVEFAELDPDQPVRGRLSGRALADGVEVPFDLYATLQRPAAARGLGLAGAIAVQAKDWRLPMRVRAGARLHAGDDGLGLDALRLGANARYRAGAGADATDLPFAFGVAGPLRYRDGELSLAPMGAALRAAADSAVPNLDAGGRFGFGQALALRWRGRIHAWPRAWPALPPPLGQSAAPLAFELDYDGKADFSDTAALRVQREQTLFDGRFRLPQMLAWIETKDGPPLPPLAGHLSTPKIEISGATLQGVEVSIEDDPPAAAPAPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKR4</accession>
    <name>A0A0S2DKR4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7 8">Elongation factor Tu</fullName>
            <shortName evidence="7">EF-Tu</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">tuf</name>
        <name evidence="12" type="ORF">BV903_21115</name>
        <name evidence="13" type="ORF">FE772_18660</name>
        <name evidence="14" type="ORF">FE772_18725</name>
        <name evidence="10" type="ORF">GLE_3792</name>
        <name evidence="11" type="ORF">GLE_3804</name>
    </gene>
    <organism evidence="10 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 15">C3</strain>
        </source>
    </reference>
    <reference evidence="12 16" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 16">B25</strain>
        </source>
    </reference>
    <reference evidence="13 17" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000067">
        <property type="protein sequence ID" value="OPD61941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948556.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000067.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3792"/>
    <dbReference type="EnsemblBacteria" id="ALN59136">
        <property type="protein sequence ID" value="ALN59136"/>
        <property type="gene ID" value="GLE_3792"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59148">
        <property type="protein sequence ID" value="ALN59148"/>
        <property type="gene ID" value="GLE_3804"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61941">
        <property type="protein sequence ID" value="OPD61941"/>
        <property type="gene ID" value="BV903_21115"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3792"/>
    <dbReference type="KEGG" id="lez:GLE_3804"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3736"/>
    <dbReference type="OMA" id="EGDKEWG"/>
    <dbReference type="OrthoDB" id="621774at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01884">
        <property type="entry name" value="EF_Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03697">
        <property type="entry name" value="EFTU_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_B">
        <property type="entry name" value="EF_Tu_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041709">
        <property type="entry name" value="EF-Tu_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033720">
        <property type="entry name" value="EFTU_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004541">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_bac/org"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00485">
        <property type="entry name" value="EF-Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 10" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="10"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="19"/>
            <end position="26"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="81"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="136"/>
            <end position="139"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN59148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OPD61941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW27363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW27375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="396" mass="43063" checksum="4D1D258D1B9AC7F4" modified="2016-02-17" version="1">MAKGKFERTKPHVNVGTIGHVDHGKTTLTAALTKVGAERFGGEFKAYDAIDAAPEEKARGITISTAHVEYESPNRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGPMPQTREHILLSRQVGVPYIVVFLNKADMVDDAELLELVEMEVRELLSKYEFPGDDTPIIHGSARLALEGDQSDIGVPAIIKLVEALDSFIPEPERAIDKPFLMPVEDVFSISGRGTVVTGRIERGIIKVGDEIEIVGIRPTQKTTVTGVEMFRKLLDQGQAGDNAGLLLRGTKRDDVERGQVLAKPGSITPHTEFEGEVYVLSKDEGGRHTPFFKGYRPQFYFRTTDITGACQLPEGVEMVMPGDNVKMVVTLINPVAMDEGLRFAIREGGRTVGAGVVSKIVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKT4</accession>
    <name>A0A0S2DKT4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3681</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59025">
        <property type="protein sequence ID" value="ALN59025"/>
        <property type="gene ID" value="GLE_3681"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3681"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3625"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="49" mass="5612" checksum="E1A88F2DDE0A43D3" modified="2016-02-17" version="1">MRWGEGGRRLESREVALFFAEHHLEFCEVRALGVGRGRRLDFFVSCASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKV7</accession>
    <name>A0A0S2DKV7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3848</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59191">
        <property type="protein sequence ID" value="ALN59191"/>
        <property type="gene ID" value="GLE_3848"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3848"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3788"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="86" mass="9607" checksum="A14C162F1D497B34" modified="2016-02-17" version="1">MPGAPTYVVGACAHRHSLRTPPAAQPLSCSDRTDRNKRRSDSKRSSLCDSYHEKIELGRVLIDNDQRDFPLLATIEHAAEYTVCIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL69</accession>
    <name>A0A0S2DL69_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">EamA/RhaT family transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Integral membrane protein DUF6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_19125</name>
        <name evidence="3" type="ORF">GLE_3893</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948627.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3893"/>
    <dbReference type="EnsemblBacteria" id="ALN59236">
        <property type="protein sequence ID" value="ALN59236"/>
        <property type="gene ID" value="GLE_3893"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3893"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3831"/>
    <dbReference type="OMA" id="GHTSFNW"/>
    <dbReference type="OrthoDB" id="1515911at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="19"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="164"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="314" mass="33732" checksum="2804345C5D1DC409" modified="2016-02-17" version="1">MSASSSASSSAAGSGAPLLQMLLGASVISSSAVFVRWVDIGPGASAFWRMGLAAVILLLLLGQPWRRERLRLWRPQPRVLGLVMLSAVFMAFDLWMWHRSIVYVGVGLSTLLANFQVFVLAGAGALFLGERAGWKLWVGLSLGLVGLALLLAPGWEHMDARFRLGVFFGLAAALAYGGFLLAFRAAQARRGDTPNEALQWWLCLGCVLVLGLTVPLGGESMWPQSAHDWLILAAYAAIAQVLGWLVIGRAMPLLPAGIVGLCLLLQPLLAYVWDVLIFHKRLGGLELLGIGLSLAGIFLGLARGDQPLFARKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLB9</accession>
    <name>A0A0S2DLB9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Bis(5'-nucleosyl)-tetraphosphatase, symmetrical</fullName>
            <ecNumber evidence="5">3.6.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ap4A hydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Diadenosine tetraphosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">apaH</name>
        <name evidence="9" type="ORF">FE772_19225</name>
        <name evidence="8" type="ORF">GLE_3915</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5">Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>H2O + P(1),P(4)-bis(5'-adenosyl) tetraphosphate = 2 ADP + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:24252"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58141"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.1.41"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the Ap4A hydrolase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.41" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3915"/>
    <dbReference type="EnsemblBacteria" id="ALN59257">
        <property type="protein sequence ID" value="ALN59257"/>
        <property type="gene ID" value="GLE_3915"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3915"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3852"/>
    <dbReference type="OMA" id="INAFTRM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008803">
        <property type="term" value="F:bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07422">
        <property type="entry name" value="MPP_ApaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00199">
        <property type="entry name" value="ApaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004617">
        <property type="entry name" value="ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000903">
        <property type="entry name" value="B5n-ttraPtase_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00668">
        <property type="entry name" value="apaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="7">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="273"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW27452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="287" mass="32528" checksum="B19E952E796AE46A" modified="2016-02-17" version="1">MSVWAIGDLQGCYDATQRLLERLKFDPAQDKLWFCGDLVNRGGQSLETLRLVHSLREHSTVVLGNHDLSLLAIGQRTEEEKRKVNPDLQRIVLADDGEALLDWLRMQKLVHADRALGWMMVHAGMAPKWTTSMAERHAREVEERLHGDQYRRLLKNMYGDRPAWNPKLAGIDRHRAIINIFTRLRYCTPRGRIAFEDKGAPGTQPVGLYPWYEVPGRAERDLKIVCGHWSTLGLFIGHGVHAIDTGAVWGGKLTALQLDTDELRLVQVPGRDVPANPPRPRPPRQPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLC9</accession>
    <name>A0A0S2DLC9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 7" type="primary">rplF</name>
        <name evidence="8" type="ORF">BV903_22960</name>
        <name evidence="9" type="ORF">FE772_18575</name>
        <name evidence="7" type="ORF">GLE_3775</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uL6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000077">
        <property type="protein sequence ID" value="OPD61602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948542.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000077.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3775"/>
    <dbReference type="EnsemblBacteria" id="ALN59119">
        <property type="protein sequence ID" value="ALN59119"/>
        <property type="gene ID" value="GLE_3775"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61602">
        <property type="protein sequence ID" value="OPD61602"/>
        <property type="gene ID" value="BV903_22960"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3775"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3719"/>
    <dbReference type="OMA" id="KPDPYKG"/>
    <dbReference type="OrthoDB" id="1398618at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.12">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01365_B">
        <property type="entry name" value="Ribosomal_L6_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000702">
        <property type="entry name" value="Ribosomal_L6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020040">
        <property type="entry name" value="Ribosomal_L6_a/b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036789">
        <property type="entry name" value="Ribosomal_L6_a/b-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019906">
        <property type="entry name" value="Ribosomal_L6_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002358">
        <property type="entry name" value="Ribosomal_L6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655">
        <property type="entry name" value="PTHR11655"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655:SF14">
        <property type="entry name" value="PTHR11655:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00347">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002162">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00059">
        <property type="entry name" value="RIBOSOMALL6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56053">
        <property type="entry name" value="SSF56053"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03654">
        <property type="entry name" value="L6_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00525">
        <property type="entry name" value="RIBOSOMAL_L6_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L6" evidence="6">
        <location>
            <begin position="12"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L6" evidence="6">
        <location>
            <begin position="88"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD61602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW27346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="175" mass="18468" checksum="B857EBF4E58956ED" modified="2016-02-17" version="1">MSRVAKKPIALPKGVEINVQADAIVAKGPKGSLSIAKPAAINLKVENNEAVFATEDAALIPLTGTLRAILANMVKGVSEGFERKLELVGVGYRAAMQGKDLSLSLGFSHPVVFQAPEGITLAAPTQTEILVQGADKQRVGEVAAKIRGFRPPEPYKGKGVKYAGEVIIRKEAKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLL6</accession>
    <name>A0A0S2DLL6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4038</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59380">
        <property type="protein sequence ID" value="ALN59380"/>
        <property type="gene ID" value="GLE_4038"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4038"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3980"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="48" mass="5379" checksum="CC3A4D96C077A250" modified="2016-02-17" version="1">MDTSRYNMSYVELEGDFVQKLEESMVNLGACNATTLILSEKSPPKPIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLY5</accession>
    <name>A0A0S2DLY5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable cytosol aminopeptidase</fullName>
            <ecNumber evidence="8">3.4.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Leucine aminopeptidase</fullName>
            <shortName evidence="8">LAP</shortName>
            <ecNumber evidence="8">3.4.11.10</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Leucyl aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pepA</name>
        <name evidence="11" type="ORF">FE772_20565</name>
        <name evidence="10" type="ORF">GLE_4194</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low.</text>
            <dbReference type="EC" id="3.4.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>Release of an N-terminal amino acid, preferentially leucine, but not glutamic or aspartic acids.</text>
            <dbReference type="EC" id="3.4.11.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the peptidase M17 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.1" evidence="8"/>
    <dbReference type="EC" id="3.4.11.10" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948860.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4194"/>
    <dbReference type="EnsemblBacteria" id="ALN59536">
        <property type="protein sequence ID" value="ALN59536"/>
        <property type="gene ID" value="GLE_4194"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4194"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4136"/>
    <dbReference type="OMA" id="MKNTGPR"/>
    <dbReference type="OrthoDB" id="356206at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00433">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00181">
        <property type="entry name" value="Cytosol_peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023042">
        <property type="entry name" value="Peptidase_M17_leu_NH2_pept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008283">
        <property type="entry name" value="Peptidase_M17_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="PTHR11963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02789">
        <property type="entry name" value="Peptidase_M17_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="SSF52949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00631">
        <property type="entry name" value="CYTOSOL_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 10" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTOSOL_AP" evidence="9">
        <location>
            <begin position="341"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="273"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="347"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW27672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="490" mass="51202" checksum="CE92063DD3CD3770" modified="2016-02-17" version="1">MTLEFDLNRDAAAAAQTDCVVVGAFADKTLTAAARTLDEASGGRLTVLLERGDISGKTGKTALLHDVPGVASPRVLVVGLGEPGKFGVAQYLKAVGDAARALKAGPVAHALLTLSEEPVAGRDAAWAIRQAAIAADHACYRYTATLGKKKDEPGLRKLSIAGGDAAALAHGQAIAAGVQFARELGNLPPNVCNPAYLAQQASEFAGRFANTECEVLDRAQMQELGMGSLLAVARGSANPPKLIVLKYSNGGDAKPYVLVGKGITFDTGGINLKVQGGIEEMKFDMCGAASVMGAFVAAVGMQLPINLVVIVPAVENMPDADAYRPSDVLTSMSGKTIEVGNTDAEGRLILCDALTYAQRFEPQALLDVATLTGACVVALGKFATGLMSKHDDLSAELIGAGEQVFDRAWRLPLWDEYQTQLESSFADVYNIGGRWAGAITAGCFLARFAEGQRWAHLDIAGVASEEGKRGLSTGRPVGMLSQWLLERGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM37</accession>
    <name>A0A0S2DM37_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 7">Transcriptional regulator MraZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">mraZ</name>
        <name evidence="11" type="ORF">BV903_07630</name>
        <name evidence="12" type="ORF">FE772_20290</name>
        <name evidence="10" type="ORF">GLE_4139</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">C3</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">YC36</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Forms oligomers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
            <location evidence="7">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MraZ family.</text>
    </comment>
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        <property type="protein sequence ID" value="ALN59481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_MTAY01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4139"/>
    <dbReference type="EnsemblBacteria" id="ALN59481">
        <property type="protein sequence ID" value="ALN59481"/>
        <property type="gene ID" value="GLE_4139"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64525">
        <property type="protein sequence ID" value="OPD64525"/>
        <property type="gene ID" value="BV903_07630"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4139"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4081"/>
    <dbReference type="OMA" id="RGQERCL"/>
    <dbReference type="OrthoDB" id="1684767at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009295">
        <property type="term" value="C:nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="MraZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MraZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003444">
        <property type="entry name" value="MraZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035644">
        <property type="entry name" value="MraZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020603">
        <property type="entry name" value="MraZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035642">
        <property type="entry name" value="MraZ_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038619">
        <property type="entry name" value="MraZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34701">
        <property type="entry name" value="PTHR34701"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02381">
        <property type="entry name" value="MraZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00242">
        <property type="entry name" value="TIGR00242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51740">
        <property type="entry name" value="SPOVT_ABRB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="11" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="9">
        <location>
            <begin position="5"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="SpoVT-AbrB" evidence="9">
        <location>
            <begin position="82"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OPD64525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW27630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="148" mass="16607" checksum="29B996CECACAB721" modified="2016-02-17" version="1">MFQGETAITIDDKGRLAVPTAYRELVARECDNRLVITYNPFESGSLYLYPLTIWERVRDQVNKLPKAKAVNRTMQLKLVGAAAFVELDGNGRITVPPSHRAAVGIEKKAVLLGMGDKFELWSEQAHHAQIRQTISDDDLSDELLDLQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM38</accession>
    <name>A0A0S2DM38_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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        <name evidence="2" type="ORF">GLE_4017</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Gammaproteobacteria</taxon>
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    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="protein sequence ID" value="ALN59359"/>
        <property type="gene ID" value="GLE_4017"/>
    </dbReference>
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        <property type="gene ID" value="BV903_00645"/>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD65796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="118" mass="12601" checksum="3D17E42DA187580B" modified="2016-02-17" version="1">MKALSQATLIELAHAGAVRGYILHGRTDGYVLSVQYGLHEAVLTAKRGGARRFARIDTALALLRTLRAAAVEVRLADAAPPARPYRRGRPAGLAALDRLHAEAAPPPPRARSLRGPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM56</accession>
    <name>A0A0S2DM56_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4312</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59653">
        <property type="protein sequence ID" value="ALN59653"/>
        <property type="gene ID" value="GLE_4312"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4312"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4251"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="38" mass="4133" checksum="41D9F3E2C26DDE12" modified="2016-02-17" version="1">MSVCRPPRPQTAGLCTNTHFLALQCDDAVRVLPSVMCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM78</accession>
    <name>A0A0S2DM78_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">YcxB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_21945</name>
        <name evidence="3" type="ORF">GLE_4494</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949098.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59835">
        <property type="protein sequence ID" value="ALN59835"/>
        <property type="gene ID" value="GLE_4494"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4494"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4431"/>
    <dbReference type="OrthoDB" id="2096402at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="YcxB"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="YcxB" evidence="2">
        <location>
            <begin position="98"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="169" mass="18813" checksum="1B8248D3E74139DB" modified="2016-02-17" version="1">MEHAQEIRFSLAFGYWDRARATLALIAERPVSLCMALLWPLWGVGLAAFALVKGRPITGELALAIALLFAFVPAMVLLGTAMTHYFHRQSREPFTYTFDGEGIHVAAVTYDFTHKWPAIFKVKRKRWFLMFFFSPGCAHCIPFRAIPDPAVQAALVSMAAAHGADVRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMB3</accession>
    <name>A0A0S2DMB3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_20645</name>
        <name evidence="2" type="ORF">GLE_4212</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948874.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4212"/>
    <dbReference type="EnsemblBacteria" id="ALN59553">
        <property type="protein sequence ID" value="ALN59553"/>
        <property type="gene ID" value="GLE_4212"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4212"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4154"/>
    <dbReference type="OMA" id="GWRTMPY"/>
    <dbReference type="OrthoDB" id="1025087at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007822">
        <property type="entry name" value="LANC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05147">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01260">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="224"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="925" mass="100895" checksum="5724A78C74783766" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DME0</accession>
    <name>A0A0S2DME0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tryptophan 2,3-dioxygenase</fullName>
            <shortName evidence="1">TDO</shortName>
            <ecNumber evidence="1">1.13.11.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Tryptamin 2,3-dioxygenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Tryptophan oxygenase</fullName>
            <shortName evidence="1">TO</shortName>
            <shortName evidence="1">TRPO</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Tryptophan pyrrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Tryptophanase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 2" type="primary">kynA</name>
        <name evidence="3" type="ORF">BV903_18570</name>
        <name evidence="4" type="ORF">FE772_21080</name>
        <name evidence="2" type="ORF">GLE_4310</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-tryptophan + O2 = N-formyl-L-kynurenine</text>
            <dbReference type="Rhea" id="RHEA:24536"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58629"/>
            <dbReference type="EC" id="1.13.11.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="1">Binds 1 heme group per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-tryptophan degradation via kynurenine pathway; L-kynurenine from L-tryptophan: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the tryptophan 2,3-dioxygenase family.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.11" evidence="1"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000051">
        <property type="protein sequence ID" value="OPD62423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948951.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000051.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4310"/>
    <dbReference type="EnsemblBacteria" id="ALN59651">
        <property type="protein sequence ID" value="ALN59651"/>
        <property type="gene ID" value="GLE_4310"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62423">
        <property type="protein sequence ID" value="OPD62423"/>
        <property type="gene ID" value="BV903_18570"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4310"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4249"/>
    <dbReference type="OMA" id="WRWRNDH"/>
    <dbReference type="OrthoDB" id="1660023at2"/>
    <dbReference type="UniPathway" id="UPA00333">
        <property type="reaction ID" value="UER00453"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004833">
        <property type="term" value="F:tryptophan 2,3-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01972">
        <property type="entry name" value="T23O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037217">
        <property type="entry name" value="Trp/Indoleamine_2_3_dOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004981">
        <property type="entry name" value="Trp_2_3_dOase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10138">
        <property type="entry name" value="PTHR10138"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03301">
        <property type="entry name" value="Trp_dioxygenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140959">
        <property type="entry name" value="SSF140959"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0823">Tryptophan catabolism</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="1">
        <location>
            <begin position="51"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="1">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="290" mass="33555" checksum="1AE6F2380FEF57A2" modified="2016-02-17" version="1">MSVEKNQRELEDGIHTDLQGRITYGGYLQLDKLLSAQRPLSQPGHHDEMLFIVQHQVSELWMKLIIHELSAALAHLRRDQVWQCQKILARCKQVLRLLTEQWSVLETLTPSEYMGFRETLGPSSGFQSLQYRTIEFMLGNKNEDMLKVFAYDPNGQADLERALAAPSLYDEFLMYLARFGHAVPAAHLQRDWRQPHVADAELQPVFERIYENTDVYWREYALCEDLVDLENQFQLWRFRHMRTVMRIIGFKRGTGGSSGVGFLRQALELTFFPELFSVRTTLAPAGGYGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN32</accession>
    <name>A0A0S2DN32_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4611</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949180.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4611"/>
    <dbReference type="EnsemblBacteria" id="ALN59952">
        <property type="protein sequence ID" value="ALN59952"/>
        <property type="gene ID" value="GLE_4611"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4611"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4546"/>
    <dbReference type="OMA" id="GCGTLWL"/>
    <dbReference type="OrthoDB" id="912110at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="5"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="366" mass="38829" checksum="D871B3944EC1FF6E" modified="2016-02-17" version="1">MASYDLIVLGAGIVGAACAERAAGEGLRVAVVEPGPVGGGATAAAMGHLVAMDDDPAELALSQLSLRLWERFAALPLAEFSRCGTLWVAREPRELDGVAAKVARLAAAGIEARPVGADELYALEPHLTPGLSGGMLVAGEAVVYPPRVAQHLLQLACERQAHALLGRRAVALTAHGARLDDGSELRGPVLVATGCALPELLPQLPMRSRKGHLVITERYPGRIRHQLLELGYADSAHGDADSSVAFNVQPRPTGQILIGSSREFGVEERAVSPPMLRRMLERAFAFVPMLRELQALRVWTGFRPCTPDGRPYIGAFAPRPHTWVAAGHEGLGVTTALGTAQLLVEQLLGRAPAIDPAPYAPTRMLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNB3</accession>
    <name>A0A0S2DNB3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar basal body protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">flgF</name>
        <name evidence="7" type="ORF">GLE_4628</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949194.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4628"/>
    <dbReference type="EnsemblBacteria" id="ALN59969">
        <property type="protein sequence ID" value="ALN59969"/>
        <property type="gene ID" value="GLE_4628"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4628"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4564"/>
    <dbReference type="OMA" id="MQSGLYV"/>
    <dbReference type="OrthoDB" id="947161at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020013">
        <property type="entry name" value="Flagellar_FlgE/F/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037925">
        <property type="entry name" value="FlgE/F/G-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117143">
        <property type="entry name" value="SSF117143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03506">
        <property type="entry name" value="FlgEFG_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="5">
        <location>
            <begin position="13"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="6">
        <location>
            <begin position="186"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="269" mass="28344" checksum="39C4DABE88162DC8" modified="2016-02-17" version="1">MDNLMLTATQMIARESQRVEVSANNIANVATPGFKRELAFHSVLGAQAAQQLQQQALDAAAGIAPDAELREGAAQAPAASRAVRRATDFAAGKLQHTGNPYDLSVTGPGFLQLATERGFVYARTAALHRDGEGRLVTAQGWRLQAAGGGDVTVSGEDWKLERDGTVVDAGNPASAVRLVEFDQLERLARAGGNAFAAPDDARMSERLPGTQGGALASAVQQGYLEAANVSVGDDMVQIMEAMRRIESAQKLVHAYDDMVGSALQRLGGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNH3</accession>
    <name>A0A0S2DNH3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Carbohydrate kinase family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Carbohydrate kinase, PfkB family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BV903_03505</name>
        <name evidence="7" type="ORF">D9T17_06740</name>
        <name evidence="6" type="ORF">FE772_22045</name>
        <name evidence="4" type="ORF">GLE_4514</name>
    </gene>
    <organism evidence="4 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 8">C3</strain>
        </source>
    </reference>
    <reference evidence="5 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">OH11</strain>
        </source>
    </reference>
    <reference evidence="6 11" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 11">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000006">
        <property type="protein sequence ID" value="OPD65365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000019">
        <property type="protein sequence ID" value="ROU07893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949113.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4514"/>
    <dbReference type="EnsemblBacteria" id="ALN59855">
        <property type="protein sequence ID" value="ALN59855"/>
        <property type="gene ID" value="GLE_4514"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65365">
        <property type="protein sequence ID" value="OPD65365"/>
        <property type="gene ID" value="BV903_03505"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4514"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4450"/>
    <dbReference type="OMA" id="SQQIARM"/>
    <dbReference type="OrthoDB" id="1604782at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00583">
        <property type="entry name" value="PFKB_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="3">
        <location>
            <begin position="35"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD65365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW27926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROU07893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="310" mass="34680" checksum="0D1D75E41E249E30" modified="2016-02-17" version="1">MSALICGSLAYDTIMVFPDQFKNHILPDKVHILNVSFLVPRMRREFGGCAGNIAYNLKLLGGDPIPMATVGQDFGPYRAHLESYGIRLDCVRVFEEQFTPQCFITTDLDNNQITAFHPGAMSNSHSNHVRDVAGVTFGIVAPDGREGMLQNSKEFAELGIPFIFDPGQAMPLFNGEELRAFIEQADYVVVNDYESNLLQTRTGWDEKQIVSRVKAYITTLGPRGAIIHTPEETYTIPPAYERRVTDPTGCGDAFRAGLIFGIEKGYDWMTIGRMGNLMGALKVEHPGTQNQRFDYAEFAEQFRQQFGYAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNR3</accession>
    <name>A0A0S2DNR3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RebB like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_15775</name>
        <name evidence="4" type="ORF">D9T17_06010</name>
        <name evidence="3" type="ORF">FE772_22740</name>
        <name evidence="1" type="ORF">GLE_4668</name>
    </gene>
    <organism evidence="1 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 5">C3</strain>
        </source>
    </reference>
    <reference evidence="2 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">OH11</strain>
        </source>
    </reference>
    <reference evidence="3 8" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000041">
        <property type="protein sequence ID" value="OPD62933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000019">
        <property type="protein sequence ID" value="ROU07762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949224.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60009">
        <property type="protein sequence ID" value="ALN60009"/>
        <property type="gene ID" value="GLE_4668"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62933">
        <property type="protein sequence ID" value="OPD62933"/>
        <property type="gene ID" value="BV903_15775"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4668"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4604"/>
    <dbReference type="OMA" id="MIMAIED"/>
    <dbReference type="OrthoDB" id="2059941at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021070">
        <property type="entry name" value="Killing_trait_RebB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11747">
        <property type="entry name" value="RebB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD62933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROU07762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="75" mass="7762" checksum="71E28C63BBC45BF8" modified="2016-02-17" version="1">MADPVNSQITDAVTQTNVKVVAEAPAQAIASLYQVSSHSTGLALQNAVHSQQVLNQISSAVVSKAVQMIMAVGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNW3</accession>
    <name>A0A0S2DNW3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Apical junction molecule protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4736</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60077">
        <property type="protein sequence ID" value="ALN60077"/>
        <property type="gene ID" value="GLE_4736"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4736"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4670"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="295" mass="33066" checksum="2CDBC19F7CF37D80" modified="2016-02-17" version="1">MFANIRTGGRTAPRRIAAQRGQGQIWLVWGLIGAVAVFVALIGIGVYVGAKRHQETQQELRALGDTGNQLIEQQRRLAEGKAPDAALAPAAPAGETVPARNEAEMLRGFNALLREIGGRSQQQQARIARELEALQLEQVLTPERLIRAEGRRTSREALRRYRELIDRSAASSLQARTELRQRLEILTSRLTARDRLRAQFDGASAKRVELEQQSIRNQRNVADLTLRTVELIERAGSRVQLQQGQLAFSSQRDLDAFNGYVGQIQAAVAEEQRLARREQELLRQAQDQFNQVARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP48</accession>
    <name>A0A0S2DP48_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5098</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60439">
        <property type="protein sequence ID" value="ALN60439"/>
        <property type="gene ID" value="GLE_5098"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5098"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5023"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="59" mass="6746" checksum="543DD19BB84A6C41" modified="2016-02-17" version="1">MRAHSTSQTWQRSRVARVFRLVARFARAHTVSAFAARDARSPGERSTDVRNAPTHQEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP75</accession>
    <name>A0A0S2DP75_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ketoacyl_synth_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4968</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949451.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4968"/>
    <dbReference type="EnsemblBacteria" id="ALN60309">
        <property type="protein sequence ID" value="ALN60309"/>
        <property type="gene ID" value="GLE_4968"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4968"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4895"/>
    <dbReference type="OMA" id="CAYDGSF"/>
    <dbReference type="OrthoDB" id="1273274at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13723">
        <property type="entry name" value="Ketoacyl-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ketoacyl_synth_N" evidence="1">
        <location>
            <begin position="46"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="275" mass="27436" checksum="C08E14985A074113" modified="2016-02-17" version="1">MSAAAHSAGARPATALAAAIEGVGYWSRGLPDWNAARAYALGGEAAPDAPARPSPQLLPANERRRAPETVAVALDVAAAACAAAGRDPAALSSVFASSHGDMAITDYMCATLAADPRAISPTRFHNSVHNAAAGYWTIGVGAMRPATALSALEASFAQGLIEALAQLAAGEAAVLLAGYDGAGYGPLGAAVPSEGLLGAALVLGRAPRAGAPRLHAWLGDPPAAPAAPGRLLQRDAGNASAPMLALFDALATGAVHRIALPAGSGRSLWLELDHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPP1</accession>
    <name>A0A0S2DPP1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Toluene ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_25325</name>
        <name evidence="5" type="ORF">GLE_5233</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949652.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5233"/>
    <dbReference type="EnsemblBacteria" id="ALN60574">
        <property type="protein sequence ID" value="ALN60574"/>
        <property type="gene ID" value="GLE_5233"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5233"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5151"/>
    <dbReference type="OMA" id="PKYLFCD"/>
    <dbReference type="OrthoDB" id="1058434at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030296">
        <property type="entry name" value="MlaF/Mkl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43023:SF6">
        <property type="entry name" value="PTHR43023:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="8"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW28475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="262" mass="27584" checksum="CB5905F2F6F6EAFC" modified="2016-02-17" version="1">MSKQTPIVRLTDLRLDRGGRSVLRGINLSVPRGSIVAVLGPSGSGKSTLLSALTGELAPASGTVEVFGRPVPQNPRELLELRKGIGVLLQGNGLLTDLTAAENVALPLRAHTRLPNPLIRRLVLMKLHAVGLSAAADAYPRELSGGMARRVALARALALDPPLMIYDEPLTGLDPIASGVVMSLVRRLNDTLGLTSIVVTHHVHETLPVADHAIVIANGGIVFSGTPAELEHSDDPLVRQFLRGEPDGPIGFDAAPRNSEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-06-17" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPQ7</accession>
    <name>A0A0S2DPQ7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5258</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60599">
        <property type="protein sequence ID" value="ALN60599"/>
        <property type="gene ID" value="GLE_5258"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5258"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5177"/>
    <dbReference type="OMA" id="INTWRES"/>
    <dbReference type="OrthoDB" id="1635582at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="242" mass="24577" checksum="D743E7EE72828FB2" modified="2016-02-17" version="1">MPAARRPHHQPMRPAPIRRGSGAADRGGAFPGDFAMTARLRGWALLLSAAAFAPAAGAFTATINPGSRGIYLRVGDGIYTGTYTGNGTPGNGGGVDVVSTTVPAAALGNGVDQIMTTTASSGVSNYDGYAFCNVPAQIYVGGFYRRSGSGGAATLTATVPAGLTNAQGQSIAFSQISWTSSGNGDTGGQPIPAGTFQPGTQALASFQINTWRESCHTFRYANDAVVGAGTYTGRVVYTLSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPU4</accession>
    <name>A0A0S2DPU4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60626">
        <property type="protein sequence ID" value="ALN60626"/>
        <property type="gene ID" value="GLE_5285"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5285"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5203"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="68" mass="7317" checksum="46EEF069A2DE0061" modified="2016-02-17" version="1">MRRPSRDRCAANFAIPAAAPATIQCARRAPAPLPVAIAAAALRTLRRKRTRTRRPAVGGRLSRATALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ28</accession>
    <name>A0A0S2DQ28_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">IS30 family transposase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Transposase for insertion sequence element</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_25360</name>
        <name evidence="5" type="ORF">GLE_5240</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the transposition of the insertion element.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transposase IS30 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949656.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60581">
        <property type="protein sequence ID" value="ALN60581"/>
        <property type="gene ID" value="GLE_5240"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5240"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5159"/>
    <dbReference type="OrthoDB" id="1780129at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025246">
        <property type="entry name" value="IS30-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001598">
        <property type="entry name" value="Transposase_IS30_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13936">
        <property type="entry name" value="HTH_38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01043">
        <property type="entry name" value="TRANSPOSASE_IS30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="4">
        <location>
            <begin position="188"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="154"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW28481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="350" mass="40131" checksum="EC0952B78AD86E74" modified="2016-02-17" version="1">MGQQYSHLSAEERGAIMVLIAQGASGRQIAQTLGRAQSTIARELRRNGFRSHSGPPLRGRPRFDPGYDATRAGRRAQRLRRRARVRRKLRRDTVLWRRVRYWLERCWSPQQIADKLRDLYPDRPWLRVSHETIYTAIYAMPRGELRRQVTRLLRQGRKSGRRTRQGSDARGHLPDLPNIRLRPPAAHERLMPGHWEGDLIVGAHNRSAIGVLVCRRTLYVKLADATAHTVLEAFSSAFEGVPESLKKTLTYDQGKEMASHRQLSERTGLAIYFADPHSPWQRGTCENTNGLLRQYFPKGTDLSVHSAQRLKEVAWEMNNRPRRSLGVRSPVEVLYEELKTLQAQGDALGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ80</accession>
    <name>A0A0S2DQ80_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Uroporphyrinogen-III synthase</fullName>
            <ecNumber evidence="1">4.2.1.75</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">hemD</name>
        <name evidence="3" type="ORF">GLE_5035</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>hydroxymethylbilane = H2O + uroporphyrinogen III</text>
            <dbReference type="Rhea" id="RHEA:18965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57845"/>
            <dbReference type="EC" id="4.2.1.75"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the uroporphyrinogen-III synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.75" evidence="1"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5035"/>
    <dbReference type="EnsemblBacteria" id="ALN60376">
        <property type="protein sequence ID" value="ALN60376"/>
        <property type="gene ID" value="GLE_5035"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5035"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4963"/>
    <dbReference type="OMA" id="MHTMTRP"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004852">
        <property type="term" value="F:uroporphyrinogen-III synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006780">
        <property type="term" value="P:uroporphyrinogen III biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06578">
        <property type="entry name" value="HemD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10090">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036108">
        <property type="entry name" value="4pyrrol_syn_uPrphyn_synt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003754">
        <property type="entry name" value="4pyrrol_synth_uPrphyn_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039793">
        <property type="entry name" value="UROS/Hem4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38042">
        <property type="entry name" value="PTHR38042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02602">
        <property type="entry name" value="HEM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69618">
        <property type="entry name" value="SSF69618"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HEM4" evidence="2">
        <location>
            <begin position="12"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="233" mass="24210" checksum="9E55E0AD429A723E" modified="2016-02-17" version="1">MIELSPWTIRSENTAVARAALASALQSAHVLVTSPNAARALRDLCAADARAAASSLPQPPQRDGQAWYAVGSGTAQALAESGIVGVRWPERMDSEGLLALPGLQRFDAGEAVGLLTAPGGRGVIAPTLAARGAQVRRADIYRREPARLDRFMVARLSQARAPLLLALSSGEALQRVLAQLPPPAAARLREARVSAASERLAQSAREAGFVDVGVAAGPGARELLAPLAHGDRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQF9</accession>
    <name>A0A0S2DQF9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_00550</name>
        <name evidence="2" type="ORF">GLE_5466</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949829.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60807">
        <property type="protein sequence ID" value="ALN60807"/>
        <property type="gene ID" value="GLE_5466"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5466"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5381"/>
    <dbReference type="OrthoDB" id="1560093at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726742" evidence="1">
        <location>
            <begin position="24"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="186" mass="18872" checksum="656754657BCFABFB" modified="2016-02-17" version="1">MKNHSLSICAGVLAMAMAPAALAQVSASKAELAQAAVGESFTIGHTEYRIAPSAVVTKPAEASTEAGRELVPGDYVVAVPAAAVASARSARSLSSGGENLGAAVSGSGDTVIVAPELNVYFSHPGVVDQLVKQTGGTLLYSSAVGGNATIGYASVSQAMQARQLIQGQAGVKEVNPRLVEQRRVPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQK6</accession>
    <name>A0A0S2DQK6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5505</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5505"/>
    <dbReference type="EnsemblBacteria" id="ALN60846">
        <property type="protein sequence ID" value="ALN60846"/>
        <property type="gene ID" value="GLE_5505"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5505"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5420"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="146" mass="16312" checksum="DC23AD244B533CAA" modified="2016-02-17" version="1">MKRRLHLVPFTVTVPPARRDPELAQKLLGERDGIVRWAVDGCLDWQQHGLEPPASVSDATQDYFEDEDAHGQWMAVAGALDPNAFALSSDLYGSWKVWAEENGEYVGSIKRLIAALAVRGLKPHRNSTGQRGLIGFRLLPRRTPRV</sequence>
</entry>
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    <accession>A0A0S2DQL5</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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            <taxon>Proteobacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    <dbReference type="EnsemblBacteria" id="ALN60810">
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        <property type="gene ID" value="GLE_5469"/>
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    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="156"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="237" mass="26127" checksum="4CBA15495DAC6239" modified="2016-02-17" version="1">MIAPARIVAARQGRTMAILGGDSYQWYLYQARQACALANARGQSGVLVKGAAFGVRAATSDKSACRLILKELGSRTVFSLPRAQVDALLKKSQRLDDAALRPDPKAKRLAARLARAEPKDFWSVVAALDWPKSSLDPAYPAIARAALRERLRAAELVRIAKAAARYRRELQKAVERLEKQAGDQLFLGGDDSFYDALAHAVSSGQRAFEAFVRKPESFVKKYNRAPVESENFESCFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQP7</accession>
    <name>A0A0S2DQP7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyltransferase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_5478</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="OMA" id="YLWHSLA"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="253"/>
            <end position="273"/>
        </location>
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            <begin position="24"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="403" mass="44133" checksum="2884780FFB2727F1" modified="2016-02-17" version="1">MADMPVGAARLQTPTPAAQAHRLPGLDVLRAIAVAWVMLFHSFLNEGPDEGLVWLCHYGWMGVDLFFVLSGYLIGSQVLAPLARGERLSFGGFYLRRAFRILPAFLAVLAVYLLVPGFRESPGLESAWKFLSFTLNLLIDYRQNQAFSHAWSLCVEEHFYLVFPLLAWWLMRRASTAAFVAICTGVVLGGIALRAGVWLHDFETEGPVGESARSWFAEDIYFPTWNRLDGLLAGVVLASLKTFRAQWWRRTQAYANVALLAGLGVVAAAMWLFRERTGLLANAIGWPVLSVGFALLVFAGATRDSWIGRWSIPGVGWLAAMSYSLYLVHKGVFHVVDESVGELLAGHSLVAFAVYGTAALAAAAVLHYGVEQPFLRLRDWALNARARTPAPGAGAVRGPALGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQX9</accession>
    <name>A0A0S2DQX9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="2 3">
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        <lineage>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN60719">
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        <property type="gene ID" value="GLE_5378"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5378"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5293"/>
    <dbReference type="OrthoDB" id="2007310at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595683" evidence="1">
        <location>
            <begin position="28"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="159" mass="16884" checksum="99E98152396EFE82" modified="2016-02-17" version="1">MKTRTWTPALAIAVAALLAAPAPAAVAATQDDGTTLTLYTGRVGTRAVTMYLQDEPAPCGGILRTISAVYRYDGVSKWLALDANSDRKGHLALVESSLGSGVSGALMLVRDGAGLKGKWISPDGERVLPVRFDPAPASARKRKEMAETLEKVHYENDDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DR33</accession>
    <name>A0A0S2DR33_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_00440</name>
        <name evidence="2" type="ORF">GLE_5442</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60783">
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        <property type="gene ID" value="GLE_5442"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5442"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5358"/>
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    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="136" mass="14216" checksum="D5C53B03616BDB12" modified="2016-02-17" version="1">MRTKAAKALRLGLGSLLLLALAATAFVATNWSGGELAAALGLPRGGAPRLGWDLAWTVAAGALALWIVARWAPVAARAQVALAWLALAAMAVWAVANLGGEFPLWFCDGLLAALPLLGGCAWRWAGLPRRSQRHRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DRC3</accession>
    <name>A0A0S2DRC3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5403</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60744">
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        <property type="gene ID" value="GLE_5403"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5403"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5318"/>
    <dbReference type="OrthoDB" id="920361at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="349"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="440" mass="47996" checksum="435C3198BAF66022" modified="2016-02-17" version="1">MFQPPPVAIEQLEGPIERLRLTAAADGRFVAWIAGQQVHGRTRDAFNAPFAWQALQRMALNALPARVGVLVYADGRREAHWAVAAGSAGLIPMPTELERKLALAQAMRWLPVLALWSIWSGVALPQAHAGLGWMLLLLIALGGTAGIAATLATQAWTWLQHRRRRPILAASEHHLVHAIGAMRKQHRVWSRRLRTAALRRAARDAARAQTQGDDWTQTLADDNAAGTVALQRLHGRLPMPWSSQGLHGEGSGMLLMDDYRFALCGRYLSLRALHGPGYPTPFLAMGDRVEVLVPAQERAEADSVYALRNLEDGRIYIAHGGFRLLAGGDPAGEHALTGFTARSYRLRGAGGAAIALIATTLCYFVFGFDPDEAGRSLERAGFFAAVFAAMIAAIALPYAWSRRRWRSGRANARERLTERVYAALDLGSPLAPLPAHAHDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-01-23" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A1EBU0</accession>
    <name>A1EBU0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5110</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2006-11" db="EMBL/GenBank/DDBJ databases">
            <title>A type III secretion system from the microbial antagonist and biological control bacterium, Lysobacter enzymogenes strain C3.</title>
            <authorList>
                <person name="Reedy R.M."/>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">C3</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="EF119743">
        <property type="protein sequence ID" value="ABL59993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60451">
        <property type="protein sequence ID" value="ALN60451"/>
        <property type="gene ID" value="GLE_5110"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5110"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5035"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ABL59993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="129" mass="12405" checksum="CD32EAFC4AA2685A" modified="2007-01-23" version="1">MSNNAINGAGGTAGLVGTFIADVNKNDAIGNGKGSRSAGGGGGGGIAAGGGAGGSNSWYAAMAKAWGSTMDAQASRITELSGSIGGGNDTPSSMISLTSESLRMQFISNSASTSINSVAQGIEKLASKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2010-01-19" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>D1M898</accession>
    <name>D1M898_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Biopolymer transport protein ExbB</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="12">Biopolymer transporter ExbB</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">ExbB</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="13">MotA/TolQ/ExbB proton channel family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="10">Transporter, MotA/TolQ/ExbB proton channel family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">exbB</name>
        <name evidence="12" type="ORF">BV903_04900</name>
        <name evidence="14" type="ORF">D9T17_03190</name>
        <name evidence="13" type="ORF">FE772_25755</name>
        <name evidence="10" type="ORF">GLE_5330</name>
        <name evidence="11" type="ORF">LEN_0010</name>
        <name evidence="15" type="ORF">SAMN05421681_108228</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2009-10" db="EMBL/GenBank/DDBJ databases">
            <title>Identification and characterization of a tonB-exbD2 gene cluster in Lysobacter enzymogenes strain OH11.</title>
            <authorList>
                <person name="Qian G."/>
                <person name="Hu B."/>
                <person name="Liu F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">OH11</strain>
        </source>
    </reference>
    <reference evidence="10 16" key="2">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 16">C3</strain>
        </source>
    </reference>
    <reference evidence="19" key="3">
        <citation type="journal article" date="2016" name="DNA Res." volume="0" first="0" last="0">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer, Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">M497-1</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="4">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">ATCC 29487</strain>
        </source>
    </reference>
    <reference evidence="11 19" key="5">
        <citation type="journal article" date="2017" name="DNA Res." volume="24" first="169" last="177">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
            <dbReference type="PubMed" id="28065880"/>
            <dbReference type="DOI" id=".1093/dnares/dsw055"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 19">M497-1</strain>
        </source>
    </reference>
    <reference evidence="12 18" key="6">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 18">B25</strain>
        </source>
    </reference>
    <reference evidence="14 20" key="7">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 20">OH11</strain>
        </source>
    </reference>
    <reference evidence="13 21" key="8">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 21">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the exbB/tolQ family.</text>
    </comment>
    <dbReference type="EMBL" id="GU121673">
        <property type="protein sequence ID" value="ACY68246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP014940">
        <property type="protein sequence ID" value="BAV95497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000009">
        <property type="protein sequence ID" value="OPD65079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000010">
        <property type="protein sequence ID" value="ROU08670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNOG01000008">
        <property type="protein sequence ID" value="SDX86333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949725.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5330"/>
    <dbReference type="EnsemblBacteria" id="ALN60671">
        <property type="protein sequence ID" value="ALN60671"/>
        <property type="gene ID" value="GLE_5330"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAV95497">
        <property type="protein sequence ID" value="BAV95497"/>
        <property type="gene ID" value="LEN_0010"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65079">
        <property type="protein sequence ID" value="OPD65079"/>
        <property type="gene ID" value="BV903_04900"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDX86333">
        <property type="protein sequence ID" value="SDX86333"/>
        <property type="gene ID" value="SAMN05421681_108228"/>
    </dbReference>
    <dbReference type="KEGG" id="lem:LEN_0010"/>
    <dbReference type="KEGG" id="lez:GLE_5330"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5247"/>
    <dbReference type="OMA" id="NRFAHDL"/>
    <dbReference type="OrthoDB" id="1796180at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000183696">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000218824">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="8">
        <location>
            <begin position="113"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ACY68246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN60671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAV95497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OPD65079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW28546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROU08670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="SDX86333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000183696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000218824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="249" mass="27311" checksum="F639CC6C3F9EFE73" modified="2010-01-19" version="1">MLQQTTTAAAGGSNAEALQQMSFSHLLQNFDLVGWIVFITLTLMSVLSVYWIVINFVKNLRLRGSSDRVVSTFWETPNAQDAIRYMEEQPRSEPFSKIALDAAQAAAHHQRHEGSRLVESLNRSEFVDRALRQAVTRESSRLEAGLTVLATVGSTAPFVGLLGTVWGIYHALLRLGASGESSIQAVAGPVGEALIMTAIGLFVAIPAVLAYNFFVRLNRVTNNKFDTFAHDLHDFFATGSRVGEVSNKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-09-13" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>Q6BCG0</accession>
    <name>Q6BCG0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beta glucanase C</fullName>
            <ecNumber evidence="6">3.2.1.-</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Carbohydrate-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Glucanase C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">gluC</name>
        <name evidence="7" type="ORF">FE772_03190</name>
        <name evidence="6" type="ORF">GLE_0490</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2005" name="Phytopathology" volume="95" first="701" last="707">
            <title>Mutagenesis of beta-1,3-Glucanase Genes in Lysobacter enzymogenes Strain C3 Results in Reduced Biological Control Activity Toward Bipolaris Leaf Spot of Tall Fescue and Pythium Damping-Off of Sugar Beet.</title>
            <authorList>
                <person name="Palumbo J.D."/>
                <person name="Yuen G.Y."/>
                <person name="Jochum C.C."/>
                <person name="Tatum K."/>
                <person name="Kobayashi D.Y."/>
            </authorList>
            <dbReference type="PubMed" id="18943787"/>
            <dbReference type="DOI" id="10.1094/PHYTO-95-0701"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
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</entry>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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</entry>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="305" mass="32991" checksum="CD31AFE05D01DCD2" modified="2016-02-17" version="1">MQADLDNAGIYKQDEIDSYAAVRFKSMAAYAAGEQAQHKEIYAATSAPTERFNDQVNQQRAAIQSAEAAFEVAKSQGNEAGMKQANATRTAHAEVLQQLLDFKSGLTRFGSLYTYIAQTIDLGDPDLEAFASFARLLAKRLHGVPPEQVDVSALVLTGFDVKPEDMPGGEEPAKEEAVILKPVGPGGGGQPELPVYLRQVIARLNSIFGEATPLTDKVALVNHLFDIVREDANTVAQIKNNPRDVAMNGNIKGSVQSALVRALGSHTDLVTQVLKNDKQALNSLVDLLYEMVKDGQNIDRAELEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA40</accession>
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            <authorList>
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            <strain evidence="5 7">C3</strain>
        </source>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6 8">YC36</strain>
        </source>
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        <property type="entry name" value="CshA_NR2"/>
    </dbReference>
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            <end position="325"/>
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            <end position="452"/>
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            <begin position="580"/>
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    </feature>
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        <source>
            <dbReference type="Pfam" id="PF01345"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF18651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN55414.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW24500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="680" mass="68643" checksum="A1467246652740C4" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAI8</accession>
    <name>A0A0S2DAI8_LYSEN</name>
    <protein>
        <submittedName>
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        </submittedName>
        <submittedName>
            <fullName evidence="4">RidA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_01420</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RutC family.</text>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN55455">
        <property type="protein sequence ID" value="ALN55455"/>
        <property type="gene ID" value="GLE_0096"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0096"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.100"/>
    <dbReference type="OMA" id="AQTHKTI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006056">
        <property type="entry name" value="RidA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00004">
        <property type="entry name" value="TIGR00004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726520" evidence="2">
        <location>
            <begin position="22"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="157" mass="16341" checksum="1B561A1AF392E6DB" modified="2016-02-17" version="1">MRWCVSAVGLSLCFLAAAACAGERPEFLASPDPAAAALPFSEAVRSGELLFLSGQIGTVPGADNALAKGGIGPEAEQTLSNIRAVLERHGASMRDVVKCTVFLADIGDWPAFNAVYRQHFSAPFPARSALAASGLAMGAKVEVECIAQAPRKAGKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAS5</accession>
    <name>A0A0S2DAS5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endoribonuclease L-PSP family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0057</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55416">
        <property type="protein sequence ID" value="ALN55416"/>
        <property type="gene ID" value="GLE_0057"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0057"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.63"/>
    <dbReference type="OMA" id="YYSQAVR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594792" evidence="1">
        <location>
            <begin position="18"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="167" mass="18073" checksum="7CD9638DD1EF7CD1" modified="2016-02-17" version="1">MPKSLLLLLFVPCAALAAPAGPHAATPTREHFAPPGWEGSYRELHYSPVVRIGDRVIVSGIPTPDGADDEAKARALFVELRKHLRSAGADLDDVVELQSFHVARDQAEFRERIAPVLKAHREFFKGHYPAWTAVAVSGLYSKGATFELRAEAVIGSGKAPRATIGKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAV1</accession>
    <name>A0A0S2DAV1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GatB/YqeY domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">GatB/Yqey domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_02355</name>
        <name evidence="1" type="ORF">GLE_0308</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945942.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0308"/>
    <dbReference type="EnsemblBacteria" id="ALN55666">
        <property type="protein sequence ID" value="ALN55666"/>
        <property type="gene ID" value="GLE_0308"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0308"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.305"/>
    <dbReference type="OMA" id="AMGAVMK"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016884">
        <property type="term" value="F:carbon-nitrogen ligase activity, with glutamine as amido-N-donor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023168">
        <property type="entry name" value="GatB_Yqey_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019004">
        <property type="entry name" value="YqeY/Aim41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042184">
        <property type="entry name" value="YqeY/Aim41_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28055">
        <property type="entry name" value="PTHR28055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09424">
        <property type="entry name" value="YqeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="SSF89095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="148" mass="16131" checksum="6829506CF36E89A5" modified="2016-02-17" version="1">MSLKQRLTEDMKAAMKSGDKHSLGVIRLINAAIKQKEVDERIELDDDAVIAVLDKMVKQRRDSVTQYEAAQRDDLAQIERDEMVVIDRYLPAKMGEAEILEVLEATIAEVGATGPADLGKLMGPLKAKLGGKADMGQVSALAKKRLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB11</accession>
    <name>A0A0S2DB11_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_05935</name>
        <name evidence="3" type="ORF">FE772_01590</name>
        <name evidence="1" type="ORF">GLE_0137</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000010">
        <property type="protein sequence ID" value="OPD65020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945822.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000010.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55496">
        <property type="protein sequence ID" value="ALN55496"/>
        <property type="gene ID" value="GLE_0137"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65020">
        <property type="protein sequence ID" value="OPD65020"/>
        <property type="gene ID" value="BV903_05935"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0137"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.140"/>
    <dbReference type="OrthoDB" id="2127251at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD65020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="168" mass="18492" checksum="66C885A0166FEDA6" modified="2016-02-17" version="1">MTESAAPKVSLSAQQLNDKLLALILSMDGPQDLTAQNIERRTGLKIEPNPEDPSGFFSTGSLPEGWFYSLISVEPVPGTPHHALLLNMGHAAEGYTDRTPVCVGLEHYRSALTSAGFKESQRPPRLGTEYRFFRSGKVNVRVELQGRTTRYDEDLCVSRVFVSGKPQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB54</accession>
    <name>A0A0S2DB54_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase, short chain dehydrogenase/reductase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0389</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0389"/>
    <dbReference type="EnsemblBacteria" id="ALN55747">
        <property type="protein sequence ID" value="ALN55747"/>
        <property type="gene ID" value="GLE_0389"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0389"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.386"/>
    <dbReference type="OMA" id="YSHFYTT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="410" mass="44256" checksum="9E586BAFA266532A" modified="2016-02-17" version="1">MSTISRAIWGGATFVIGHRFRDGSGVGESKLLEKLPPDRLARREEWGDGAGFTRSEEVRRYFRCPVHWEQSTMAKKPTRSKGGASDHLVQASATSQRQQAIQADVERKDARKAASSGKREPVQAGPRQHPENPLPKQHQSKPGHEHLLKPAPEFLARDYRGSGKLDGKVALVTGGDSGIGRAVAVLYAREGADVAIVYLSEHQDAHDTRACIEDEGRRSLAISGDVRDSRFCADAVAQVVDAFGRLDILVNNAAFQEHSDTLEDLSEAHLQETLQTNIAGYFYMARAALAHLPRGGAIINTGSETGLFGNARLLDYSATKGAIHAFTKSLASQLLPRGIRVNAVAPGPVWTPLNPADRSAEEIAKFGRDSDMGRPAQPEEISPAYVFLASAVMSSYINGVVLPVMGGPHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB61</accession>
    <name>A0A0S2DB61_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0416</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55774">
        <property type="protein sequence ID" value="ALN55774"/>
        <property type="gene ID" value="GLE_0416"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0416"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.413"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="58" mass="6204" checksum="6E890847AC6FBA2C" modified="2016-02-17" version="1">MGNERPAVIKTVLQKGSAIPSSEALRANSASAAEFKAAMIELNTPTSHERAFLDEFAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBC6</accession>
    <name>A0A0S2DBC6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0233</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0233"/>
    <dbReference type="EnsemblBacteria" id="ALN55592">
        <property type="protein sequence ID" value="ALN55592"/>
        <property type="gene ID" value="GLE_0233"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0233"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.235"/>
    <dbReference type="OMA" id="ACDCELG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="51" mass="5332" checksum="97B8CC309FCDD1CC" modified="2016-02-17" version="1">MSDKTCAACDCPLDETAFQVTIGGKTVEVCCDDCARKLDAAYASAQSPDRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBF3</accession>
    <name>A0A0S2DBF3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA polymerase sigma factor SigX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">sigX</name>
        <name evidence="5" type="ORF">GLE_0510</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946087.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55868">
        <property type="protein sequence ID" value="ALN55868"/>
        <property type="gene ID" value="GLE_0510"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0510"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.505"/>
    <dbReference type="OMA" id="HYIATIR"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="3">
        <location>
            <begin position="13"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="4">
        <location>
            <begin position="109"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN55868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="176" mass="19990" checksum="568604FB7543B0EE" modified="2016-02-17" version="1">MSASEQSRLAESLARQYGRLVFQAAYRVLGDAAQAEDVQQEVFLRLLQSDGRDAIESWPAYLSAAASRAAIDVLRRQRRWWRALPLWRAQQPGAAESAEQANLHDERARRLRQALAGLPRREAQCFGLRYLEGMEIDQIARSLRLSANNVNVILHRARRRLEAELAERGDTTEIAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBP0</accession>
    <name>A0A0S2DBP0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_03620</name>
        <name evidence="3" type="ORF">GLE_0585</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946143.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55943">
        <property type="protein sequence ID" value="ALN55943"/>
        <property type="gene ID" value="GLE_0585"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0585"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.578"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="157" mass="16527" checksum="22AB45DC3F733D53" modified="2016-02-17" version="1">MAASSRLPVALLGSAVLILGVLIWKPWSAPRDPAPSAAGAASADALGAAPRSAQPLGEAPQLSGPQRQAALAETVRSAAPQAQPPQSYKGPDGKQHEIVYNRGLALSPGAREELKRQRLQQMRDQPEAISKIYGIGRDEIAAVLAGKQPFPDRLIDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBQ7</accession>
    <name>A0A0S2DBQ7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sigma factor regulatory protein, FecR/PupR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_0601</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946153.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0601"/>
    <dbReference type="EnsemblBacteria" id="ALN55959">
        <property type="protein sequence ID" value="ALN55959"/>
        <property type="gene ID" value="GLE_0601"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0601"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.593"/>
    <dbReference type="OMA" id="WIARENT"/>
    <dbReference type="OrthoDB" id="1381035at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006860">
        <property type="entry name" value="FecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032623">
        <property type="entry name" value="FecR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012373">
        <property type="entry name" value="Ferrdict_sens_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30273">
        <property type="entry name" value="PTHR30273"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16220">
        <property type="entry name" value="DUF4880"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04773">
        <property type="entry name" value="FecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018266">
        <property type="entry name" value="FecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4880" evidence="3">
        <location>
            <begin position="22"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="FecR" evidence="2">
        <location>
            <begin position="138"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN55959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="364" mass="39608" checksum="2CD4458A6FB8E34C" modified="2016-02-17" version="1">MKCKIALVRDGSAEPGSRSIDEDAARWSEILRERDDATMREAFQAWQAQSPGHAEAYARAEAARRLADLLADEPEMQSLRSETLGRVARQGQARRASRRNWAMAASLTVAGLLGALGLNLGDSWRMVGDARDALAGNVYRTGVGQRERFTLADGSVITLNTDSRVSTHYRDGLRAVTLERGQALFKVAKDRSRPFVVSAGGRQVTALGTEFDVYLSPRAFEVTLLEGRVTVTRTVKPAAVASARPTAAATAPLAELRPGEQFVALAKAAPQVRAADVRRVVSWRNGQIVFENERLGDAVAEINRYSQRKIVLADATLASLKISGAFNTGDTGTFVEALTDYFPIERDTLDNDDIVLKPRAPLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBV3</accession>
    <name>A0A0S2DBV3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulAtor containing a LytTR DNA-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_0647</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946187.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0647"/>
    <dbReference type="EnsemblBacteria" id="ALN56005">
        <property type="protein sequence ID" value="ALN56005"/>
        <property type="gene ID" value="GLE_0647"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0647"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.636"/>
    <dbReference type="OMA" id="FRANRKH"/>
    <dbReference type="OrthoDB" id="1958442at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="6"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="151"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="253" mass="28004" checksum="650FDCBD6A060F52" modified="2016-02-17" version="1">MSERILAVLAEDEAPQRQALLDALAQAWPELDVAACEDGDEALEAVRALRPQVAFLDIRMPAVGGLDVAREAIAGGALVVFTTAYDEYAVRAFEAGAADYLLKPVSRERLDQAVARVRERLRQARPDDWRARLDALEAQLRPQGDRLIRWIGASVGDSVRMIGIDEVVYFQAQEKYVRVVTGDGEALVRTPVKELLAGLDPGLFWQVHRGLVVRVAAIDRVRRNELGRHELSLKARAEILPVSAAFASRFRGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC21</accession>
    <name>A0A0S2DC21_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_04235</name>
        <name evidence="1" type="ORF">GLE_0711</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946239.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56069">
        <property type="protein sequence ID" value="ALN56069"/>
        <property type="gene ID" value="GLE_0711"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0711"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.699"/>
    <dbReference type="OMA" id="HDIDERF"/>
    <dbReference type="OrthoDB" id="51092at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="759" mass="85210" checksum="9D11B83BEE1928C9" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC66</accession>
    <name>A0A0S2DC66_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_15545</name>
        <name evidence="2" type="ORF">GLE_0586</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000040">
        <property type="protein sequence ID" value="OPD63046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55944">
        <property type="protein sequence ID" value="ALN55944"/>
        <property type="gene ID" value="GLE_0586"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63046">
        <property type="protein sequence ID" value="OPD63046"/>
        <property type="gene ID" value="BV903_15545"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0586"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.579"/>
    <dbReference type="OrthoDB" id="776014at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594954" evidence="1">
        <location>
            <begin position="17"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="390" mass="40507" checksum="FA7D3CCE4F1EC7DC" modified="2016-02-17" version="1">MYCLLAAALLSGNALAQSADGYGTILRLPLVVNSSTYSSTIFVRNAGTATASVKVTYYGAPGTPFAGERPCTTLSVAPNAVASGTLADLCAVPAGAASNYGQIALVEQSAANIPVTAYSRIQSFAGVGFSVEGFKIGSLGSGANDSIVTGLRRQAAAPGYQSNCFVASINEPVQVTWQLRDASGSQLGNQQVTNLSANETVRILDVFTAAGAPAGDYSNVQATFRGTTPTANPAFAAYCTTQENATFDGDFRIAKTADPQDDRSKKIGTSSSSALGTLLGLLSGQDRFGLYLQAPDYVSCRLDGTGAPQLEMRLEDPQGNVIAGGNNISSFQKVYLGERSTHNNGVNGLYVLKVESRNLLSLMINYGVTCETGNGANPPLFIGHAIAEEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC81</accession>
    <name>A0A0S2DC81_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLE_0602</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55960">
        <property type="protein sequence ID" value="ALN55960"/>
        <property type="gene ID" value="GLE_0602"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0602"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.594"/>
    <dbReference type="OMA" id="NGRDDRW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011662">
        <property type="entry name" value="Secretin/TonB_short_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00965">
        <property type="entry name" value="STN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <keyword evidence="4 7" id="KW-0798">TonB box</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594731" evidence="9">
        <location>
            <begin position="32"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="domain" description="STN" evidence="10">
        <location>
            <begin position="61"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="125"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="152"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN55960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1137" mass="123116" checksum="28A043B3CD4EF00E" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCB8</accession>
    <name>A0A0S2DCB8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Branched-chain amino acid aminotransferase</fullName>
            <ecNumber evidence="2">2.6.1.42</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ilvE</name>
        <name evidence="2" type="ORF">GLE_0821</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.6.1.42" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0821"/>
    <dbReference type="EnsemblBacteria" id="ALN56179">
        <property type="protein sequence ID" value="ALN56179"/>
        <property type="gene ID" value="GLE_0821"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0821"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.810"/>
    <dbReference type="OMA" id="GMQCYEG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052656">
        <property type="term" value="F:L-isoleucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052654">
        <property type="term" value="F:L-leucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052655">
        <property type="term" value="F:L-valine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="SSF56752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="320" mass="34736" checksum="311E9297031F56C8" modified="2016-02-17" version="1">MRERAPAPSRSGEAFDAAEGSESRARGEVPVSQRQPVIWFDGQFIAGDAPEAPLTTHAMHYGTAVFEGIRSYATGDGGAAVFRLPEHLERMRKGADMFGIDFDVERAGRAVLDTLRANGHRDAYIRPLTWMGTGSIGLDVDPLSQHLMVATIAKVVHLGGARTRLTVSPWKRNPATSLPPLKLSGAYVNSILAKREAKQRGFDEALFTDDKGYVVECTGANVFMVKNGEVTSVEHRDALPGITRDTMIALSGAASREVTLHELLDADEVFVCGTAAEACAIDVLDRRVFGDNPVTRELSALYAKVVRGQDSRYAHWLTAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCI8</accession>
    <name>A0A0S2DCI8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB-dependent siderophore receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FE772_05010</name>
        <name evidence="10" type="ORF">GLE_0872</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946360.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0872"/>
    <dbReference type="EnsemblBacteria" id="ALN56230">
        <property type="protein sequence ID" value="ALN56230"/>
        <property type="gene ID" value="GLE_0872"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0872"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.861"/>
    <dbReference type="OMA" id="GAKNIQD"/>
    <dbReference type="OrthoDB" id="173242at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015344">
        <property type="term" value="F:siderophore uptake transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010105">
        <property type="entry name" value="TonB_sidphr_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01783">
        <property type="entry name" value="TonB-siderophor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242117" evidence="7">
        <location>
            <begin position="26"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="73"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="248"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN56230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW25125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="700" mass="77323" checksum="2267B1C19DBC9619" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCM0</accession>
    <name>A0A0S2DCM0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">ATP-dependent protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_05070</name>
        <name evidence="2" type="ORF">GLE_0881</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946365.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0881"/>
    <dbReference type="EnsemblBacteria" id="ALN56239">
        <property type="protein sequence ID" value="ALN56239"/>
        <property type="gene ID" value="GLE_0881"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0881"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.870"/>
    <dbReference type="OrthoDB" id="585089at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_AAA_core" evidence="1">
        <location>
            <begin position="184"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="356" mass="39138" checksum="FE1D263E3E4CF95C" modified="2016-02-17" version="1">MSTDHSPYGAVFNHQLWDLSSLILNTRLAAALDRGVARYPIHRSLRLAARTHVDAMFDDLATQLGLSAHRPNGRSLLLDGEGVFVDARAGSKADYCSFYFGIWADSVERAEAVLQAVQARIEPVRIREPMFSIDWNFLSGNGELQSASIEELADDVLLDEAYPEIGDVTGFIDRYLRAKETVLVLQGRPGTGKTRLIRAILGEISRRNEGSAQALYTGDKKALECDEIYVKFITGDDHAFVVEDADHLLRPRAEGNEHLHRFLAIADGVVRAQGRKIVFSTNLPNVGDLDDALVRPGRCFAHVDVRELRLDEAAVLIRRLAGERGLDADAAIAAVAGSGNRSHSLAAIYQAVDRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCN0</accession>
    <name>A0A0S2DCN0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fimbrial protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Pilus assembly protein PilP</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Type IV assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pilP</name>
        <name evidence="3" type="ORF">BV903_12305</name>
        <name evidence="5" type="ORF">D9T17_22605</name>
        <name evidence="4" type="ORF">FE772_05315</name>
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    </gene>
    <organism evidence="2 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">C3</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 9" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD63603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000056">
        <property type="protein sequence ID" value="ROU04641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_0935"/>
    <dbReference type="EnsemblBacteria" id="ALN56293">
        <property type="protein sequence ID" value="ALN56293"/>
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    </dbReference>
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        <property type="protein sequence ID" value="OPD63603"/>
        <property type="gene ID" value="BV903_12305"/>
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        <property type="component" value="Chromosome"/>
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    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
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        <property type="entry name" value="Pilus_assembly_PilP"/>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="29"/>
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        <location>
            <begin position="30"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU04641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="183" mass="19678" checksum="7A2774A1DA655FBA" modified="2016-02-17" version="1">MRASSVSKPSRLFAACAVVLALSATGCFRSITSTPGEAPNLEKWVAEVKARPAPPLDPLPVMQQFETFEYAAQDLRDPFSTAFTDEDSGSGVRPDKVRRKQPLEAFPLDGLDMVGTLGTGKNIVALVMAPDKVTYRVRPGAYMGQNDGRVTGVSEERIDLVELVPDGAGGWLERPASVALEDQ</sequence>
</entry>
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    </protein>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <begin position="27"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN56386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="422" mass="44757" checksum="543CB2A639F9F055" modified="2016-02-17" version="1">MTVRNKLLPLNFAIALSLGLAGAASAAEPAPLFAAPAASLARSADADSAFKAAKAERAAVRVDLVRADAAQITETQDQLLLNLAPGVSLKAHKLQAETKPGGVVVWQGMVGDPNAQLKRINQFTGAELIDNPEESAILVRQGGQISGTVRSGGKLYRIDPLKGQGHAISLIDESKMPEDHPSSYAALPMPPLKLDPAFDEAKAGEKAPTVVRVMVVYTQAAANAVGNTLTKANLAITESNQSFANSAVNVRFELAGQYTDSYVSAGFDTDLSRFAGTTDAYLNNYHTTRNTIKADVNVLIITDPAYCGLGYLNSSAANAFSVVGASCMTGYYSFAHEIGHNFGAHHDPNNGNNTIYPYGHGYWGPGNAWRTIMAYNCGSNCPRLNYWSNPNITYNGSPMGTTAKSNNARVLNQRAATVAGFR</sequence>
</entry>
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    <accession>A0A0S2DCX2</accession>
    <name>A0A0S2DCX2_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">RTX toxins and related Ca2+-binding protein</fullName>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="entry name" value="Effector_pro_NleD-like"/>
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    </dbReference>
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        <location>
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    </feature>
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        <location>
            <begin position="207"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="428"/>
            <end position="448"/>
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    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="529"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="226"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
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</entry>
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    <accession>A0A0S2DCX9</accession>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH LytTR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="38" mass="4474" checksum="AA384C53D1EAC444" modified="2016-02-17" version="1">MKSVEPAVGDGYELELRDGSRIEVSRRQLWELRERLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDA1</accession>
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    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1168</name>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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        <property type="gene ID" value="GLE_1168"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="40" mass="4586" checksum="1CF0B25940CAF665" modified="2016-02-17" version="1">MKWSQALDASSVQIKWLHSRPEKTTLSFSDFDWLPACDCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDF7</accession>
    <name>A0A0S2DDF7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1215</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946604.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1215"/>
    <dbReference type="EnsemblBacteria" id="ALN56572">
        <property type="protein sequence ID" value="ALN56572"/>
        <property type="gene ID" value="GLE_1215"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1215"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1200"/>
    <dbReference type="OMA" id="MGAWDIG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025355">
        <property type="entry name" value="DUF4259"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14078">
        <property type="entry name" value="DUF4259"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="140" mass="14489" checksum="4850224BA46744C2" modified="2016-02-17" version="1">MGAWGVGTFENDDALDWLGDLTDTDDSAAVRALLAQALASDCLDAPDATTALAAAETVLSMLDAATPALAWHEEFAAWLPRHAAVADAGLGAAAVAAIDRVLGEESELRELWEETDDADDWRAAVAALRSALVARLAASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDH5</accession>
    <name>A0A0S2DDH5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PTS sugar transporter subunit IIA</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_16380</name>
        <name evidence="4" type="ORF">FE772_06470</name>
        <name evidence="2" type="ORF">GLE_1190</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000043">
        <property type="protein sequence ID" value="OPD62855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946584.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1190"/>
    <dbReference type="EnsemblBacteria" id="ALN56548">
        <property type="protein sequence ID" value="ALN56548"/>
        <property type="gene ID" value="GLE_1190"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62855">
        <property type="protein sequence ID" value="OPD62855"/>
        <property type="gene ID" value="BV903_16380"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1190"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1175"/>
    <dbReference type="OMA" id="GIDYNSM"/>
    <dbReference type="OrthoDB" id="1810962at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00211">
        <property type="entry name" value="PTS_IIA_fru"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016152">
        <property type="entry name" value="PTrfase/Anion_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002178">
        <property type="entry name" value="PTS_EIIA_type-2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00359">
        <property type="entry name" value="PTS_EIIA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55804">
        <property type="entry name" value="SSF55804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51094">
        <property type="entry name" value="PTS_EIIA_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00372">
        <property type="entry name" value="PTS_EIIA_TYPE_2_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PTS EIIA type-2" evidence="1">
        <location>
            <begin position="5"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="154" mass="16449" checksum="76321B62F2C88FF6" modified="2016-02-17" version="1">MPLYDLLSAERVAILGSPGDRNAVLETAARLLSGGDPRTAAALDLGLRERERLASTAIGHGVAIPHGRTPLLETSCGAFLRLAQPVDFGAADGEPVDLVLAMAVPEHHVQQHLQLLAELAERFADPDFRDCLRSAPDAAELSHRLLDCCRRSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDJ0</accession>
    <name>A0A0S2DDJ0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphonate metabolism protein PhnM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">phnM</name>
        <name evidence="1" type="ORF">GLE_1207</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946596.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1207"/>
    <dbReference type="EnsemblBacteria" id="ALN56564">
        <property type="protein sequence ID" value="ALN56564"/>
        <property type="gene ID" value="GLE_1207"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1207"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1192"/>
    <dbReference type="OMA" id="MSLMDHT"/>
    <dbReference type="OrthoDB" id="1026967at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019700">
        <property type="term" value="P:organic phosphonate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012696">
        <property type="entry name" value="PhnM"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038971">
        <property type="entry name" value="PhnM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02318">
        <property type="entry name" value="phosphono_phnM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="380" mass="40790" checksum="0E13B4BD67A28542" modified="2016-02-17" version="1">MSPRELLLDNARLVLPDRVVNGHLRVVGGRIRELGEGRLRTPSARDCDGDYLLPGLVELHTDNLEKHLLPRPGAHWPAAAAVRAHDAQLLAAGIATALNAISVGEEEAEQAVEPQTVLAALAQAREDGGLRIEHAVHLRCELPCPDLPQRLQPLLDAPQLRLLSLMDHTPGQRQFHDLERYRAYSARHGTARDDAGFGAHVRHLQDLQHRHAAGHRRIVLAMARERGLPLASHDDSELGHIAEAVDAGARIAEFPVNLATALAARAAGLSVLAGAPNLVRGGSHSGNVAASELARAGALDALSSDYVPGSLLLAAFQLGAWDSIGLPRAVAMVTHTPARAAGYDDRGALEVGQRADLLRVRVVRGFPHLEAVWIGGERRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDX1</accession>
    <name>A0A0S2DDX1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_07045</name>
        <name evidence="2" type="ORF">GLE_1315</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946681.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56672">
        <property type="protein sequence ID" value="ALN56672"/>
        <property type="gene ID" value="GLE_1315"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1315"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1299"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726798" evidence="1">
        <location>
            <begin position="42"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="177" mass="19791" checksum="DD13793D24147D72" modified="2016-02-17" version="1">MSHATLAPATSVQRKRAGALISSLRGAALATVLLFSAGAQADPAVAAQILQTIRYERQVFDVQMQQVNWYLDHDPSRAQTALIMARVEAVKIDAKLKRLVQENLASRDAGQYNDLQALERAIEYGRTASQRIKFVEVYLQTLEIERPPSAFTRQMLNTQILLFNMSMQQLEQAMAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDY8</accession>
    <name>A0A0S2DDY8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aldehyde-activating protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">GFA family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Glutathione-dependent formaldehyde-activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BV903_13040</name>
        <name evidence="6" type="ORF">FE772_07485</name>
        <name evidence="4" type="ORF">GLE_1416</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">C3</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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            <end position="116"/>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD63461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
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            <dbReference type="EMBL" id="QCW25528.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="116" mass="12600" checksum="5D0FAB89CE59CEA6" modified="2016-02-17" version="1">MASYSGSCHCGAIAYEVQGELKEAYDCNCSMCSRRGGLLWFVPSEAFALKTERADVATYRFNKHAIDHHFCTQCGIAPFSEGKMPDGAPMVAINARCLQDVDLGAVKIVAIDGRSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDZ7</accession>
    <name>A0A0S2DDZ7_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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            <end position="23"/>
        </location>
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            <begin position="24"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="113" mass="11465" checksum="3FA92A5BD40B3909" modified="2016-02-17" version="1">MRNILWIAALAASLGAGAGAAVAQTPVQADAQVRADAVQPTAAPAANAGAKTGAGVAATAVDPTCLKQTGSRIAARGKRDCAGQGRSYDRKDLQRTGETDVGQALRKLDPRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
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    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN56702">
        <property type="protein sequence ID" value="ALN56702"/>
        <property type="gene ID" value="GLE_1345"/>
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    <dbReference type="PATRIC" id="fig|69.6.peg.1327"/>
    <dbReference type="OMA" id="HVDIYPY"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="entry name" value="Plug_dom_sf"/>
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        <property type="entry name" value="TonB-dep_rcpt"/>
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    <dbReference type="InterPro" id="IPR000531">
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TONB_DEPENDENT_REC_2"/>
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    </dbReference>
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    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="3 6" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
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            <end position="752"/>
        </location>
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            <end position="168"/>
        </location>
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        <location>
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        <source>
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        <source>
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        <source>
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        <source>
            <dbReference type="RuleBase" id="RU003357"/>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN56702.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW25476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="752" mass="82499" checksum="337ADD5BFDA9F1F2" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE67</accession>
    <name>A0A0S2DE67_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">GLE_1484</name>
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    <organism evidence="3 5">
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        <lineage>
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    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946813.1">
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    </dbReference>
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        <property type="protein sequence ID" value="ALN56841"/>
        <property type="gene ID" value="GLE_1484"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1484"/>
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    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="103" mass="10418" checksum="9E4FAF675A6559B9" modified="2016-02-17" version="1">MKPPPPGSSDPAETAQAAAASGRPARDGARSAGKWLMLLALGVLLAGLVAYQLILGDGLDNYGTVFFPLALVVACIAVPLALIGAAMWLAGVARAQRAGKPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE82</accession>
    <name>A0A0S2DE82_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1414</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1414"/>
    <dbReference type="EnsemblBacteria" id="ALN56771">
        <property type="protein sequence ID" value="ALN56771"/>
        <property type="gene ID" value="GLE_1414"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1414"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1394"/>
    <dbReference type="OMA" id="APWRDNF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002763">
        <property type="entry name" value="DUF72"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036520">
        <property type="entry name" value="UPF0759_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30348">
        <property type="entry name" value="PTHR30348"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01904">
        <property type="entry name" value="DUF72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117396">
        <property type="entry name" value="SSF117396"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="312" mass="34122" checksum="BFC9CCEFFFC89AFF" modified="2016-02-17" version="1">MSKRNDSMPAAGDLFGAPVPAPAKKAPPKPSQPVGDDPLAGAAGVEAIDGIRCGIGGWTYAPWRDNFYPPKLVQRRELEYASRRLSSIEINGTFYSAQKPATYAKWAAQTPETFAFSLKAPGRVTQAGALAKASAQARAFIDGGLAEFGERLGPILWQLAPSRRFDADDLAPFLDALPRTLDGRALKHVLEVRHPSFLSPQYLQFARERRIATVFTDSDEYPSLADITGDFVYARLMRSRAEVATGYPDDELDDWARRARAWARGEDNPELPHVAAPTPAAAAREVFVYFISAAKHRNPAAAMRLIGKLRGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEF0</accession>
    <name>A0A0S2DEF0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_07155</name>
        <name evidence="1" type="ORF">GLE_1344</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946703.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56701">
        <property type="protein sequence ID" value="ALN56701"/>
        <property type="gene ID" value="GLE_1344"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1344"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1326"/>
    <dbReference type="OrthoDB" id="2051539at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="100" mass="11250" checksum="C2507B9150E861A0" modified="2016-02-17" version="1">MNEYSLSFPEDYAADAPIWESKGFYCEACLLAGGRSYRLFFYEPVRLAQDIAADLGQCGAFFEPNLVVVAAVNREHMERAARWLVETRQLTALKPEADAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEG0</accession>
    <name>A0A0S2DEG0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">40-residue yvtn family beta-propeller repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1673</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946966.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1673"/>
    <dbReference type="EnsemblBacteria" id="ALN57030">
        <property type="protein sequence ID" value="ALN57030"/>
        <property type="gene ID" value="GLE_1673"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1673"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1652"/>
    <dbReference type="OMA" id="GQRVWQM"/>
    <dbReference type="OrthoDB" id="302683at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011045">
        <property type="entry name" value="N2O_reductase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50974">
        <property type="entry name" value="SSF50974"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594896" evidence="1">
        <location>
            <begin position="21"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="335" mass="35311" checksum="335C110AED5A3573" modified="2016-02-17" version="1">MLLRPLCLPLLLLAALPATSAELLVGNKSADTVWRLSLEDGRKLGEFATRKAPHEIVVAPDGKTALVANYGGSDAAGDTLSVLDLRGKAPPRIVELGRHGRPHGLRFLPGGREALATTEASQHLLRIDVASGRIVAEIALGEGKGHMVAVAADGKSAYVTKVDRGTLSRIDLARNRKAEEVEAGAGAEGVAVRPGSGEVWVSNREAGTVTVHQPRTLAILRTLPSPGFPIRVAFTADGRHALVSNARAATLSVFDAQRKRPLATVALSRDGAQYRDTMLGRAALPIGVVADPVRPRVYVAISGGDEIAVIDRATWKPVAYWKTGREPDAVAVAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEP5</accession>
    <name>A0A0S2DEP5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PAP2 superfamily protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Phosphatase PAP2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_07000</name>
        <name evidence="6" type="ORF">D9T17_19210</name>
        <name evidence="5" type="ORF">FE772_08490</name>
        <name evidence="3" type="ORF">GLE_1636</name>
    </gene>
    <organism evidence="3 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">C3</strain>
        </source>
    </reference>
    <reference evidence="4 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">OH11</strain>
        </source>
    </reference>
    <reference evidence="5 10" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 10">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000013">
        <property type="protein sequence ID" value="OPD64632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000047">
        <property type="protein sequence ID" value="ROU05257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946935.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000047.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1636"/>
    <dbReference type="EnsemblBacteria" id="ALN56993">
        <property type="protein sequence ID" value="ALN56993"/>
        <property type="gene ID" value="GLE_1636"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64632">
        <property type="protein sequence ID" value="OPD64632"/>
        <property type="gene ID" value="BV903_07000"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1636"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1616"/>
    <dbReference type="OMA" id="VFWYVLM"/>
    <dbReference type="OrthoDB" id="1930882at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="acidPPc" evidence="2">
        <location>
            <begin position="64"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD64632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROU05257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="183" mass="19782" checksum="332F5381D37ECEA7" modified="2016-02-17" version="1">MNRLPLRKRLIAGESGWCLRANRLGQRSGSRAYFAAVSRLGDGVFWYALMAVLVLADGYDGLRASVHLAATGVIALALYKALKRWTRRPRPFASDQRIHAWVAPLDEFSFPSGHTLHAVAFSLVAMAHYPALGWILVPFTASVAASRVVLGLHYPSDVLAATVIGSTLAGISLWLVPGVTLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEQ1</accession>
    <name>A0A0S2DEQ1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Polyphosphate kinase</fullName>
            <ecNumber evidence="6 7">2.7.4.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP-polyphosphate phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Polyphosphoric acid kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 12" type="primary">ppk</name>
        <name evidence="14" type="synonym">ppk1</name>
        <name evidence="13" type="ORF">BV903_07050</name>
        <name evidence="14" type="ORF">FE772_08540</name>
        <name evidence="12" type="ORF">GLE_1647</name>
    </gene>
    <organism evidence="12 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">C3</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">B25</strain>
        </source>
    </reference>
    <reference evidence="14 17" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>[phosphate](n) + ATP = [phosphate](n+1) + ADP</text>
            <dbReference type="Rhea" id="RHEA:19573"/>
            <dbReference type="Rhea" id="RHEA-COMP:9859"/>
            <dbReference type="Rhea" id="RHEA-COMP:14280"/>
            <dbReference type="ChEBI" id="CHEBI:16838"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="6 7">An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the polyphosphate kinase 1 (PPK1) family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.1" evidence="6 7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000013">
        <property type="protein sequence ID" value="OPD64641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946943.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1647"/>
    <dbReference type="EnsemblBacteria" id="ALN57004">
        <property type="protein sequence ID" value="ALN57004"/>
        <property type="gene ID" value="GLE_1647"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64641">
        <property type="protein sequence ID" value="OPD64641"/>
        <property type="gene ID" value="BV903_07050"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1647"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1626"/>
    <dbReference type="OMA" id="NIKWARK"/>
    <dbReference type="OrthoDB" id="76567at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009358">
        <property type="term" value="C:polyphosphate kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008976">
        <property type="term" value="F:polyphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006799">
        <property type="term" value="P:polyphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1840.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00347">
        <property type="entry name" value="Polyphosphate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003414">
        <property type="entry name" value="PP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041108">
        <property type="entry name" value="PP_kinase_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024953">
        <property type="entry name" value="PP_kinase_middle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036830">
        <property type="entry name" value="PP_kinase_middle_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025200">
        <property type="entry name" value="PPK_C_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025198">
        <property type="entry name" value="PPK_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036832">
        <property type="entry name" value="PPK_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30218">
        <property type="entry name" value="PTHR30218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02503">
        <property type="entry name" value="PP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13090">
        <property type="entry name" value="PP_kinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17941">
        <property type="entry name" value="PP_kinase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13089">
        <property type="entry name" value="PP_kinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015589">
        <property type="entry name" value="PP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140356">
        <property type="entry name" value="SSF140356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03705">
        <property type="entry name" value="poly_P_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 6 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PP_kinase_N" evidence="9">
        <location>
            <begin position="25"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="PP_kinase" evidence="8">
        <location>
            <begin position="139"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="PP_kinase_C_1" evidence="11">
        <location>
            <begin position="346"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="PP_kinase_C" evidence="10">
        <location>
            <begin position="517"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphohistidine intermediate" evidence="6">
        <location>
            <position position="449"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="389"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="419"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="482"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="578"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="606"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF13090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN57004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OPD64641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW25708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="699" mass="78099" checksum="115B8756DCF2A830" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEU0</accession>
    <name>A0A0S2DEU0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">VWA domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">von Willebrand factor, type A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_08970</name>
        <name evidence="3" type="ORF">GLE_1740</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947018.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57095">
        <property type="protein sequence ID" value="ALN57095"/>
        <property type="gene ID" value="GLE_1740"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1740"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1717"/>
    <dbReference type="OMA" id="RNENDYE"/>
    <dbReference type="OrthoDB" id="692608at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR022156">
        <property type="entry name" value="Uncharacterised_YfbK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12034">
        <property type="entry name" value="DUF3520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12450">
        <property type="entry name" value="vWF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242657" evidence="1">
        <location>
            <begin position="29"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="245"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="615" mass="65127" checksum="A74693DA5848D902" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEV9</accession>
    <name>A0A0S2DEV9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1822</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947073.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57174">
        <property type="protein sequence ID" value="ALN57174"/>
        <property type="gene ID" value="GLE_1822"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1822"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1793"/>
    <dbReference type="OrthoDB" id="1847097at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="285" mass="30136" checksum="1EA88C43442DDEA5" modified="2016-02-17" version="1">MTPEGGAVPVPLRTGDVLLLRARGPLAALTAWFGESRFDHVALVGRAGYLIETGPGGVVERALAERLADPELIEAQARRPLVAQRPLQDADRIAVLAHALSLRSPAFAGDPLAALGRAAALRDRALPDSAPLRAVLCEALLHAAGDNAGAMSASEFVYRCLAENPAQPRARLTPLLPAASPPALAFPELDWEALWRQVAPWLRAPRREALGMDAGGAIAAGLAAGPEQLEHAQALARQRLGLMERGNALLAHAGPRQPNPKCVRLRELEQSPSLQPLATLREPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF54</accession>
    <name>A0A0S2DF54_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57207">
        <property type="protein sequence ID" value="ALN57207"/>
        <property type="gene ID" value="GLE_1855"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1855"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1826"/>
    <dbReference type="OMA" id="DIAWYEL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="701"/>
            <end position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="723" mass="80917" checksum="5CC6BA33B4861083" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFA9</accession>
    <name>A0A0S2DFA9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PGAP1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1918</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947143.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1918"/>
    <dbReference type="EnsemblBacteria" id="ALN57269">
        <property type="protein sequence ID" value="ALN57269"/>
        <property type="gene ID" value="GLE_1918"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1918"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1884"/>
    <dbReference type="OMA" id="CMNDLQW"/>
    <dbReference type="OrthoDB" id="1573721at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012908">
        <property type="entry name" value="PGAP1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07819">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="426" mass="46144" checksum="17BDA5C6984D7DC4" modified="2016-02-17" version="1">MSTKRSAPNETGYGGDLRGIGRLTIDAITGVADLVESVHATIAALPGPFGAPVYDPTRGLTGQVYRGVRGVARLVGGALDLGLAQVAPWLDRIESLPQRDAAISALNGVLGDHLDETGNPLAIGMRLCSGGRPLPSGRKALGAALPQAGGKLVVFVHGLCMNDRQWRWNGHDYGAELARDAGWTPVYLRYNSGRHISFNGRDFSARLDRLLRDWPVPVERLAIVCHSMGGLVARSACHAAAQARHGWIDRLDSLVFLGTPHQGAPLERAGSWFDTVIQLSPYTAPFARLGKIRSAGIQDLRHGNLLDSDWRAHADRKRAGADARADTRTPVPLPKGVRSYAIAVSTDARRARDEGDQRRDDPPSGDGLVPVASALGQHRNPAFDLRIPASRQWLGYGLHHLDLLGDAQVYAQLRRWLKPARRTRTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFH1</accession>
    <name>A0A0S2DFH1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1741</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57096">
        <property type="protein sequence ID" value="ALN57096"/>
        <property type="gene ID" value="GLE_1741"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1741"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="97" mass="10835" checksum="D244E86AABE27A3A" modified="2016-02-17" version="1">MEGEARRLRTGDGGHGGFPGVWTWEGERAGSVDGVKRGDCFFGAFPRRRHCRARTPPTPSFPPHRHFPNTVIPAKAGTHFDLAFPPFPHEKSERKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFK1</accession>
    <name>A0A0S2DFK1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Condensation/amino acid adenylation/thioesterase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_1848</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57200">
        <property type="protein sequence ID" value="ALN57200"/>
        <property type="gene ID" value="GLE_1848"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1848"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1819"/>
    <dbReference type="OMA" id="MNTVEFI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043604">
        <property type="term" value="P:amide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020802">
        <property type="entry name" value="PKS_thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00824">
        <property type="entry name" value="PKS_TE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="971"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="3">
        <location>
            <position position="1006"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1276" mass="135687" checksum="424C18C4A8A529E9" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFN5</accession>
    <name>A0A0S2DFN5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2047</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947241.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57397">
        <property type="protein sequence ID" value="ALN57397"/>
        <property type="gene ID" value="GLE_2047"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2047"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2012"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="149" mass="15912" checksum="B941E521C875FDF9" modified="2016-02-17" version="1">MYAVLTLEPHHPTVLRAIEMILAGASLLPAPSEHCGPIQPGQLALLDLSPAARSVLVLVGSADDDRLSGHADWDSYRAALEQRIDLADFDQVHAVACPIHGTQTIRFALGAFAADLQRRRDDAQGWLFAVPGAASFQAQGWAPAAPPPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFP0</accession>
    <name>A0A0S2DFP0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">ATP phosphoribosyltransferase</fullName>
            <shortName evidence="11">ATP-PRT</shortName>
            <shortName evidence="11">ATP-PRTase</shortName>
            <ecNumber evidence="4 11">2.4.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11 14" type="primary">hisG</name>
        <name evidence="15" type="ORF">BV903_17285</name>
        <name evidence="16" type="ORF">FE772_09695</name>
        <name evidence="14" type="ORF">GLE_1897</name>
    </gene>
    <organism evidence="14 17">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">C3</strain>
        </source>
    </reference>
    <reference evidence="15 18" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 18">B25</strain>
        </source>
    </reference>
    <reference evidence="16 19" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 19">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + ATP</text>
            <dbReference type="Rhea" id="RHEA:18473"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="2.4.2.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="11">Feedback inhibited by histidine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the ATP phosphoribosyltransferase family. Long subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.17" evidence="4 11"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000046">
        <property type="protein sequence ID" value="OPD62686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947127.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000046.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1897"/>
    <dbReference type="EnsemblBacteria" id="ALN57248">
        <property type="protein sequence ID" value="ALN57248"/>
        <property type="gene ID" value="GLE_1897"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62686">
        <property type="protein sequence ID" value="OPD62686"/>
        <property type="gene ID" value="BV903_17285"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1897"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1865"/>
    <dbReference type="OMA" id="YVMMDYD"/>
    <dbReference type="OrthoDB" id="1419568at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003879">
        <property type="term" value="F:ATP phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00079">
        <property type="entry name" value="HisG_Long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013820">
        <property type="entry name" value="ATP_PRibTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018198">
        <property type="entry name" value="ATP_PRibTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001348">
        <property type="entry name" value="ATP_PRibTrfase_HisG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020621">
        <property type="entry name" value="ATP_PRibTrfase_HisG_long"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013115">
        <property type="entry name" value="HisG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403">
        <property type="entry name" value="PTHR21403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01634">
        <property type="entry name" value="HisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08029">
        <property type="entry name" value="HisG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00070">
        <property type="entry name" value="hisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03455">
        <property type="entry name" value="HisG_C-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01316">
        <property type="entry name" value="ATP_P_PHORIBOSYLTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 11" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HisG" evidence="12">
        <location>
            <begin position="60"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="HisG_C" evidence="13">
        <location>
            <begin position="231"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN57248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OPD62686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QCW25898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="304" mass="32821" checksum="516DE92F780DB1EA" modified="2016-02-17" version="1">MSPPASAAVRDRLRIAIQKSGRLADPARQLLAACGLSWRESRDRLFCYGETLPVDLLLVRDDDIPGLIADGVCDLGVVGRNVLLEQDGDRRGNGRAPAFREWRALGFGGCRLAIAVPDAWQWQGPQDLAGKRIATSYPALLTQWLAQQGVDAQVVLLSGSVEIAPRLGQAEAICDLVSSGATLSANQLKAVQTLVESEAVLAGPVDRFDDVRGELADLLLRRLDGALRVRNSKLLMFQAPRGLLSELLPLLPDAEQPTVMRLDDGDDVALQALCHGAVTWQRLEELKRAGARGLMVLPVEGMLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFQ6</accession>
    <name>A0A0S2DFQ6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2079</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57429">
        <property type="protein sequence ID" value="ALN57429"/>
        <property type="gene ID" value="GLE_2079"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2079"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2044"/>
    <dbReference type="OMA" id="DMFPLVR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018531">
        <property type="entry name" value="DUF1993"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36922">
        <property type="entry name" value="PTHR36922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09351">
        <property type="entry name" value="DUF1993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="165" mass="18501" checksum="1D8B66F2AFDA3DD3" modified="2016-02-17" version="1">MYSASVPVLQQLLGSLSTILERTQAHAAERKIDADAYLQARLFPDMFPLLRQVQIACDFAKGIGARLADVAVPVYDDSERGFDELQALIAKTRAFLDGLEPALFEGADDREIVLRPGTPKERRFTGRDYLVHYGLPQFFFHATTAYAILRSNGVEIGKRDFMGQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFR1</accession>
    <name>A0A0S2DFR1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glyoxalase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_10340</name>
        <name evidence="2" type="ORF">GLE_2038</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947235.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2038"/>
    <dbReference type="EnsemblBacteria" id="ALN57388">
        <property type="protein sequence ID" value="ALN57388"/>
        <property type="gene ID" value="GLE_2038"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2038"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2003"/>
    <dbReference type="OMA" id="FEADWYV"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="2"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="141" mass="15068" checksum="DDB7961E2A18A289" modified="2016-02-17" version="1">MKIASFYPVLMTADVAATAAFYRTHFGFVALFEADWYVHLQSADDPSVNLAVLDGDHATIPESGRGRVGGLLLNFEVEDVDAVHARLVAAGLPVLLSLRDEAFGQRHFITADPNGVLLDIITPIAPSAEFAAQYADGALPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFV9</accession>
    <name>A0A0S2DFV9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA pseudouridine synthase A</fullName>
            <ecNumber evidence="4">5.4.99.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridine(38-40) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridylate synthase I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-uridine isomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 9" type="primary">truA</name>
        <name evidence="10" type="ORF">FE772_10830</name>
        <name evidence="9" type="ORF">GLE_2145</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 7">
            <text>uridine(38/39/40) in tRNA = pseudouridine(38/39/40) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:22376"/>
            <dbReference type="Rhea" id="RHEA-COMP:10085"/>
            <dbReference type="Rhea" id="RHEA-COMP:10087"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.12" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947314.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2145"/>
    <dbReference type="EnsemblBacteria" id="ALN57495">
        <property type="protein sequence ID" value="ALN57495"/>
        <property type="gene ID" value="GLE_2145"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2145"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2109"/>
    <dbReference type="OMA" id="FLYGMVR"/>
    <dbReference type="OrthoDB" id="1075262at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02570">
        <property type="entry name" value="PseudoU_synth_EcTruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00171">
        <property type="entry name" value="TruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PTHR11142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001430">
        <property type="entry name" value="tRNA_psdUrid_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00071">
        <property type="entry name" value="hisT_truA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="PseudoU_synth_1" evidence="8">
        <location>
            <begin position="168"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4 5">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 6">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN57495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW26091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="281" mass="30987" checksum="ADA1BC8C1692A4A1" modified="2016-02-17" version="1">MNDSDIASAAAPLRRYALGVEYDGSEFSGWQRLVRPGEPSRPEHAPRGEATVQTTLEQALSFVAGTGIEVVCAGRTDAGVHASCQVVHFDSPVERDPRGWTLGATSRLPPSVCVRWCIPVAPDFHARFSARARRYRYRILNRPVRPALQRQYLSWERRPLDADAMHRAAQALLGENDFSAFRTVHCQAPHARRDLQSIAVRRDGDIVEMEVQANAFLHHMVRNIVGSLLPVGRGDRPEGWIAELLAGRDRTVAGPTAPSAGLVFVGPRYPAECQLPAEVCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGA2</accession>
    <name>A0A0S2DGA2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_20255</name>
        <name evidence="1" type="ORF">GLE_2263</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000061">
        <property type="protein sequence ID" value="OPD62100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947408.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000061.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2263"/>
    <dbReference type="EnsemblBacteria" id="ALN57612">
        <property type="protein sequence ID" value="ALN57612"/>
        <property type="gene ID" value="GLE_2263"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62100">
        <property type="protein sequence ID" value="OPD62100"/>
        <property type="gene ID" value="BV903_20255"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2263"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2228"/>
    <dbReference type="OMA" id="CPQSICV"/>
    <dbReference type="OrthoDB" id="100736at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD62100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="764" mass="85547" checksum="207F4F6B6816B908" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGD3</accession>
    <name>A0A0S2DGD3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF218 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2245</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947395.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2245"/>
    <dbReference type="EnsemblBacteria" id="ALN57594">
        <property type="protein sequence ID" value="ALN57594"/>
        <property type="gene ID" value="GLE_2245"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2245"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2210"/>
    <dbReference type="OMA" id="LWFTRWQ"/>
    <dbReference type="OrthoDB" id="1879123at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06259">
        <property type="entry name" value="YdcF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003848">
        <property type="entry name" value="DUF218"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02698">
        <property type="entry name" value="DUF218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="DUF218" evidence="2">
        <location>
            <begin position="76"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="248" mass="25553" checksum="2C53E29212D0D95F" modified="2016-02-17" version="1">MSAAAWLTQPLHASAVGLALAALVWLLHWRRSALALGVLAVAWSLLWSLPAAAGALRDSLQRGYLGQSAEGLPQADVIVVLGGGIGRVSAFARGDADAPELAGNRVAAAARAWQAGRAPAMLVSGGASASTRGVSEAAIMADALVELGVPRAALVLEDASGDTRANAERSARIAAERGWKRAILVTSALHMPRALQWFQRAGLPALPLAPEPPVAAAPPEAWTPSMRTLDESAQALREYAGLVVATFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGI0</accession>
    <name>A0A0S2DGI0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2386</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57735">
        <property type="protein sequence ID" value="ALN57735"/>
        <property type="gene ID" value="GLE_2386"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2386"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2348"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="63" mass="6824" checksum="F34E8BD1D5AD50C5" modified="2016-02-17" version="1">MSAARVRPLRASIAAVRSLQAGSAVPARTVRDRSAARRSSCGRGFSPDAFRSGRRARIQKRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGK2</accession>
    <name>A0A0S2DGK2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57534">
        <property type="protein sequence ID" value="ALN57534"/>
        <property type="gene ID" value="GLE_2185"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2185"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2147"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="148" mass="15106" checksum="1111071C930AEC9C" modified="2016-02-17" version="1">MHEPLQGGEARCHGCRSEGRWTDSSRAAARPRGDAGASSARSSVALPRGARAATQAAASALRCCGAAGLGVGARGCANARTRERANARNPRAGGGRCSAQAPRKIGRPGTGNCARRPSRPLHRSAIGAPRPEPAAATACDTNITRVIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGS5</accession>
    <name>A0A0S2DGS5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_12215</name>
        <name evidence="2" type="ORF">GLE_2444</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947541.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2444"/>
    <dbReference type="EnsemblBacteria" id="ALN57793">
        <property type="protein sequence ID" value="ALN57793"/>
        <property type="gene ID" value="GLE_2444"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2444"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2407"/>
    <dbReference type="OMA" id="DMVETDP"/>
    <dbReference type="OrthoDB" id="1389691at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="75"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="212" mass="22864" checksum="000B31AC364C24BC" modified="2016-02-17" version="1">MPFLDPALVLAWQTAHCIARNAPAPVPDRGGWRVDTHSDKETRRWVFPRLCEGLREIAEEITAPLHYLKLAGTTEELRSALPLRWEIQPANYFMIATAAPTDTRPLPQGYTLELHRAGAFARASVIAPDGELAAGGNAAQTADAFVYDRIETAPDHRRKGLGLSVMAALATANTSAATPQLLVATEDGRSLYARLGWSVLGPFATAVIPAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGY0</accession>
    <name>A0A0S2DGY0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2351</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57700">
        <property type="protein sequence ID" value="ALN57700"/>
        <property type="gene ID" value="GLE_2351"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2351"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2313"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="82" mass="9193" checksum="73A44CEB227A2EF0" modified="2016-02-17" version="1">MISLLPLFVLALERDAVVPQPRRACAWMRTRAMGQDAPYGAAPRPVLDLVALDPKKTRPFLWLLSLWLKTKKVTRPLADGSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH21</accession>
    <name>A0A0S2DH21_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbohydrate kinase family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Kinase, pfkB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_12725</name>
        <name evidence="3" type="ORF">GLE_2534</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947615.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2534"/>
    <dbReference type="EnsemblBacteria" id="ALN57883">
        <property type="protein sequence ID" value="ALN57883"/>
        <property type="gene ID" value="GLE_2534"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2534"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2496"/>
    <dbReference type="OMA" id="PWPKAGT"/>
    <dbReference type="OrthoDB" id="1604782at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002139">
        <property type="entry name" value="Ribo/fructo_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00990">
        <property type="entry name" value="RIBOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="2">
        <location>
            <begin position="30"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="332" mass="34878" checksum="626B95CDC3A06B21" modified="2016-02-17" version="1">MTDAPARFDPLPDPPPASPADPPRFNIVGDVSVDLVLGTLDGWPKIGTERLLPRSELRAGGSAANSALAARHLGLSPHLIGAIGDDDLAQWLLLQLSGIRVDLQTCSSDTTMSVGLLHTGGERTFFTSCGHLQHLAPEFVLRHLPPAAPGSIALFTAPFLLPGLRERFAALLAQAAARGYQIALDTGWPPEGWTPQVHREVAGWLAYCDHLLVNELETMSIAGDDSLESAVRRVAGLLKPGAHLIVKLGAAGALGHVDGRSTLHATQAAADVFDTVGAGDSFNTGYLAARLNRAGLSDALAAGCRTASAILPRFPRKRIAAGELAHCLQPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH47</accession>
    <name>A0A0S2DH47_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_2566</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947642.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57915">
        <property type="protein sequence ID" value="ALN57915"/>
        <property type="gene ID" value="GLE_2566"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2566"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2525"/>
    <dbReference type="OMA" id="GIDREVH"/>
    <dbReference type="OrthoDB" id="145346at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
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        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
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        <location>
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        </location>
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        <location>
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            <end position="451"/>
        </location>
    </feature>
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        <location>
            <begin position="463"/>
            <end position="491"/>
        </location>
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        <location>
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        <location>
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        </location>
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        </location>
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        <location>
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        </location>
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        <location>
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            <end position="954"/>
        </location>
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        <location>
            <begin position="966"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1010"/>
            <end position="1033"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1033" mass="108524" checksum="30AF41EF315ACF8C" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHC7</accession>
    <name>A0A0S2DHC7_LYSEN</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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        <name type="scientific">Lysobacter enzymogenes</name>
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    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
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    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2511"/>
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    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF20043">
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        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="308" mass="34835" checksum="CF94E172B8A78A85" modified="2016-02-17" version="1">MSVMFSQPPRAGAEDVALSKDASIAWHELEGPGGLPMLVIDNALEDPHRVRECAWASRFHTPGPNEYYPGWQATAQMSGEKRLIQDLGKLFLDRLWSRGWPPPLTVADLVPHSTFSVFGMDHEVARRNGYIDQHVDTFSWIAVVTYLFEHDERAGYDRGTAFWKHRPTDLKTFFLGDLLQAAQIEQLFGLNFIDPFRKASVRLRAASMAEAQKQILENPASTRRLFSLEEDNHWSLLKFVPARFNRMVAYPTWQFHSIVDTSPIQALSTRNARLTYNTFIPYPVPAGLGPQPKYQGGGYAAIDGMRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHL5</accession>
    <name>A0A0S2DHL5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2 3">NipSnap family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_12130</name>
        <name evidence="2" type="ORF">GLE_2426</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="RefSeq" id="WP_057947530.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57775">
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        <property type="gene ID" value="GLE_2426"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2426"/>
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    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="11"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="118" mass="13458" checksum="AEEE25A6025AE166" modified="2016-02-17" version="1">MTIAPAPARLVEIRTYRLKPGHGPRFETAMAQTLPMLRASGMDVVVFVRSDHEHESYCLIRAYADRAQLNAQQDAFYSSDAWRQGPHQSLIDCLQDYLNTLLWLAPDSIEDLRARNGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI25</accession>
    <name>A0A0S2DI25_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glutathione-dependent peroxiredoxin</fullName>
            <ecNumber evidence="3">1.11.1.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_13670</name>
        <name evidence="5" type="ORF">GLE_2732</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62632"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58297"/>
            <dbReference type="EC" id="1.11.1.27"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peroxiredoxin family. Prx5 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.27" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947773.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2732"/>
    <dbReference type="EnsemblBacteria" id="ALN58080">
        <property type="protein sequence ID" value="ALN58080"/>
        <property type="gene ID" value="GLE_2732"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2732"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2690"/>
    <dbReference type="OMA" id="GYINHPK"/>
    <dbReference type="OrthoDB" id="892697at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03013">
        <property type="entry name" value="PRX5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037944">
        <property type="entry name" value="PRX5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430">
        <property type="entry name" value="PTHR10430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 3" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="3"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW26555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="158" mass="17473" checksum="69B783DB7C2F71BE" modified="2016-02-17" version="1">MSIQVGDRLPEVALKRINEGIETVDTRALFDDRKAVLFAVPGAFTPTCSEKHLPGFVEHFQQFRDKGIEVACLAVNDPFVMQAWAQSQHVPDGMLMLSDGNGDLTRALGLELDASAYGMGTRAKRFALYAENGVVKQLHVEQPGEYRVSSAEYMLEQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI38</accession>
    <name>A0A0S2DI38_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0276 protein GLE_2967</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2967</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0276 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947946.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
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        <property type="gene ID" value="GLE_2967"/>
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    <dbReference type="GO" id="GO:0004519">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
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    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="290" mass="31446" checksum="AE50076E61790C47" modified="2016-02-17" version="1">MTASHAPPRAAGLGLRRALIPQLLAMDAGAVDFLECAPDNWIGVGGRNGAALARLAARFPLSGHGLSLSLGGTAPLDLELLRRTRGFLDRFDIALYSEHLSYCSDDGHLYDLLPIPFTEEAVRHVAARIRQAQDALGRRIAVENVSYYAAPHQALAEVDFLLAVLAEADCDLLLDLNNLYVNAHNHGYDARAFLARLPAARIASMHIAGHYDDEGGLKIDTHGAPVRDDVWALLAEAYARFGVRPTLLERDFGFPPLSELLAEVERIRSLQTAAARAAARPAERAEPAHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI42</accession>
    <name>A0A0S2DI42_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2854</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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        </lineage>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="OMA" id="AMHGHGW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="141" mass="15423" checksum="AC19A889917EBEE7" modified="2016-02-17" version="1">MAGTALGVVWTSPISALGLLAGLLAMPFGARARWRGRDLALVFQHWPWGPGGAITLGNVILHTGHDLDSLCHTYAHDAGHGEEPPICLADHERAHVYQYMVLGPLFLPLYLACGGISVRNRFERAADRYAQTGRGWWPWPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ31</accession>
    <name>A0A0S2DJ31_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58417">
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595102" evidence="1">
        <location>
            <begin position="30"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="75" mass="8247" checksum="8BF90E8142448F10" modified="2016-02-17" version="1">MKSFAMLKTRRAGLALALFAFAFAFGATAAPRDLIVCAGGVYCYDLQRECEQEHGAGAYYCELQWRSCVLDACPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ33</accession>
    <name>A0A0S2DJ33_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="GLE_3186"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="49" mass="5068" checksum="B77FE07DA89EE082" modified="2016-02-17" version="1">MAWRHAGGQELGRLRAGARACAHGSAAMARGAGRRRVGERGGLTGRRGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJJ1</accession>
    <name>A0A0S2DJJ1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RHS repeat-associated core domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_17080</name>
        <name evidence="1" type="ORF">GLE_3466</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW27093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="GLE_3466"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3466"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3413"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="1155" mass="122959" checksum="6D6343123EC5C93E" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJZ9</accession>
    <name>A0A0S2DJZ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_17335</name>
        <name evidence="1" type="ORF">GLE_3524</name>
    </gene>
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        <lineage>
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    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948354.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58868">
        <property type="protein sequence ID" value="ALN58868"/>
        <property type="gene ID" value="GLE_3524"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3524"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3468"/>
    <dbReference type="OrthoDB" id="1944735at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="103" mass="11892" checksum="66BFEC088B38BE10" modified="2016-02-17" version="1">MPLELIQARHQSAIHDSRKLFVVDERFHAQLFARAPSPNEYPLLHQLRDYYADATLLLGDLPRLHAELERLTAQFTERTQVREFSRFVAQAIADGDNLYATAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK41</accession>
    <name>A0A0S2DK41_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type IV pilus assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pilW</name>
        <name evidence="2" type="ORF">GLE_3578</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3578"/>
    <dbReference type="EnsemblBacteria" id="ALN58922">
        <property type="protein sequence ID" value="ALN58922"/>
        <property type="gene ID" value="GLE_3578"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3578"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3522"/>
    <dbReference type="OMA" id="GDMTGTD"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043683">
        <property type="term" value="P:type IV pilus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032092">
        <property type="entry name" value="PilW"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16074">
        <property type="entry name" value="PilW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="399" mass="42254" checksum="F5067DF085ACE042" modified="2016-02-17" version="1">MKTSHAQHGLSLIELMVALAIGAMLVLGLLQVFSASRTAYQLSEGLARVQENARFAVDYMQRDLRMVGHQGCVNDQARFLTNPAGFRSTFVAETQPTEAQFAAAAAQLQFQVSVQGYEAQGTAPGGSVTLPTSGAWAGSPALPTYIKNLSPAPAAGSDVVVLRYFSPEGVPLETFASGTTTTMTVEKDRWDKVIASSGLAEPAILGVADCIGATAFQASAIVASANKVTVSVAATGLNKSSMITDNFTTGQAMLYRAESEVFYVAYRADGNPALFRARFSATKNGTAVTPVIEELVRGIENMQLIYGMDSQANSALPPTGFIASQMVADKVQTGASTVPWRRVGLVQVALLSRANTPSAALAPAELPRLLGVQVTPPTDTRYRAVYETTIAMRNRLYGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKA6</accession>
    <name>A0A0S2DKA6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase, short chain dehydrogenase/reductase family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_16855</name>
        <name evidence="2" type="ORF">GLE_3586</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000045">
        <property type="protein sequence ID" value="OPD62763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3586"/>
    <dbReference type="EnsemblBacteria" id="ALN58930">
        <property type="protein sequence ID" value="ALN58930"/>
        <property type="gene ID" value="GLE_3586"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62763">
        <property type="protein sequence ID" value="OPD62763"/>
        <property type="gene ID" value="BV903_16855"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3586"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3530"/>
    <dbReference type="OMA" id="SPIGHIE"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="252" mass="25780" checksum="7169413E92874C8F" modified="2016-02-17" version="1">MTEAAARSNDPQAGAQALAGRVVLVTGAAGGLGSAASVAAAAAGATVVLLGRKLPKLNRVYDAAAQAGPEPLLYPLDLEGAQPDDYAEMAQRIESELGRLDGVLHCAADFPGLTPLLQTDPAAFARAVHVNLTAPWWLSQACLPLLAKAGDAALVFALDDPARVGQAYWGGYGAAQHGLAALVGILHAELGNSSVRVAGLRPGPMRTPLRARAYVEESDRSAREPSAYAQACVTLLSAAGAGHRGTVWAPHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKC6</accession>
    <name>A0A0S2DKC6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase, families S8 and S53</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_3545</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3545"/>
    <dbReference type="EnsemblBacteria" id="ALN58889">
        <property type="protein sequence ID" value="ALN58889"/>
        <property type="gene ID" value="GLE_3545"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3545"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3489"/>
    <dbReference type="OMA" id="ENTHNPY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595169" evidence="4">
        <location>
            <begin position="27"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="5">
        <location>
            <begin position="142"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="463" mass="47848" checksum="15D38ACD251CF2CA" modified="2016-02-17" version="1">MQRNRRTLVKLTALALGMAASGVSLAAARLDAALERALAGAADTAPLEVVVAYNQPGPLRAAQVQALKLLGIDKGVSMRALPIAGALATPAQIRALSQRGDVLSIHLNKPLRYYNQEARELSGVDRVQANPGDFGRTVPFTGRGVAVMINDSGIDATHADLKYGQRVVQNVQALTNLHSLLDFLPVTVLENQLNTDISSGHGTHCAGTVGGSGAQSAGLYRGVATGAALVGYGSGAVISILDAVGGYDFAISHKNSFASPIRVISNSWGTSGAFDPTDPVNLASYEAYKNGIVSVFAAGNDGPNANTHNPYAQAPWVISVGAGNKDGTLADFSSRGNPGESGGFTMPDGQAWTYVNEPTLVATGVDIVSTRALTGALPLLAAQQDAALGARAPFYTHMSGTSMATPHVAGIVALLLEAKPSLQPLEVKQILSQTANSMPGRQRFEVGSGHVDAYEAVGVANAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKI6</accession>
    <name>A0A0S2DKI6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Molybdenum cofactor biosynthesis protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">moaB</name>
        <name evidence="5" type="ORF">FE772_18810</name>
        <name evidence="4" type="ORF">GLE_3820</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May be involved in the biosynthesis of molybdopterin.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MoaB/Mog family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948576.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3820"/>
    <dbReference type="EnsemblBacteria" id="ALN59163">
        <property type="protein sequence ID" value="ALN59163"/>
        <property type="gene ID" value="GLE_3820"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3820"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3762"/>
    <dbReference type="OMA" id="TGWDGIL"/>
    <dbReference type="OrthoDB" id="1528139at2"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00886">
        <property type="entry name" value="MogA_MoaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012245">
        <property type="entry name" value="MoaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013484">
        <property type="entry name" value="MoaB_proteobac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43232">
        <property type="entry name" value="PTHR43232"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006443">
        <property type="entry name" value="MoaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02667">
        <property type="entry name" value="moaB_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="3">
        <location>
            <begin position="13"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00015262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR006443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW27385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="172" mass="18763" checksum="66EF7A45C5B8918A" modified="2016-02-17" version="1">MTAERDFIPLNLCVLTVSDSRTLANDRSGDYLIQSLTDAGHRLVERKLLPDDRYKLRAAVSQWIADDGVDGILVTGGTGFTGRDSTPEALLPLLDKEMPGFGELFRAISFDEIGTSTLQSRAFAGLANATFLFCLPGSTSACRTAWEKIVGAQLDARTRPCNLATLRPRLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKJ7</accession>
    <name>A0A0S2DKJ7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FE772_17095</name>
        <name evidence="8" type="ORF">GLE_3470</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948315.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3470"/>
    <dbReference type="EnsemblBacteria" id="ALN58815">
        <property type="protein sequence ID" value="ALN58815"/>
        <property type="gene ID" value="GLE_3470"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3470"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3417"/>
    <dbReference type="OMA" id="PYNKLID"/>
    <dbReference type="OrthoDB" id="771837at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="244"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="366"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="409"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="442"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="473"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="528"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="569"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M1" evidence="7">
        <location>
            <begin position="868"/>
            <end position="1047"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW27096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="1191" mass="133993" checksum="42341DF8EBB08655" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKK7</accession>
    <name>A0A0S2DKK7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">dTDP-4-dehydrorhamnose 3,5-epimerase</fullName>
            <ecNumber evidence="3 7">5.1.3.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Thymidine diphospho-4-keto-rhamnose 3,5-epimerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rfbC</name>
        <name evidence="9" type="ORF">BV903_24830</name>
        <name evidence="10" type="ORF">FE772_17915</name>
        <name evidence="8" type="ORF">GLE_3641</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-beta-L-rhamnose</text>
            <dbReference type="Rhea" id="RHEA:16969"/>
            <dbReference type="ChEBI" id="CHEBI:57649"/>
            <dbReference type="ChEBI" id="CHEBI:62830"/>
            <dbReference type="EC" id="5.1.3.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate biosynthesis; dTDP-L-rhamnose biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.13" evidence="3 7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000100">
        <property type="protein sequence ID" value="OPD61209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948437.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000100.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3641"/>
    <dbReference type="EnsemblBacteria" id="ALN58985">
        <property type="protein sequence ID" value="ALN58985"/>
        <property type="gene ID" value="GLE_3641"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61209">
        <property type="protein sequence ID" value="OPD61209"/>
        <property type="gene ID" value="BV903_24830"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3641"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3585"/>
    <dbReference type="OMA" id="KTPEIAC"/>
    <dbReference type="OrthoDB" id="1618609at2"/>
    <dbReference type="UniPathway" id="UPA00124"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008830">
        <property type="term" value="F:dTDP-4-dehydrorhamnose 3,5-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019305">
        <property type="term" value="P:dTDP-rhamnose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000888">
        <property type="entry name" value="dTDP_sugar_isom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21047">
        <property type="entry name" value="PTHR21047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00908">
        <property type="entry name" value="dTDP_sugar_isom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01221">
        <property type="entry name" value="rmlC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <feature type="site" description="Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose" evidence="6">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR600888-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR600888-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD61209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="185" mass="20831" checksum="F91D9C08746B223F" modified="2016-02-17" version="1">MKIIDTDLPGCRVLEPQVFGDARGFFYESFNQDKLDAAGLRLRFVQGNVSSSARGVLRGLHYQWPKPQGKLVSVLDGEVWDVAVDIRRGSPHFGRWTAVVLSAENKRHFWVPEGFAHGFVVLSERATFSYLCTNTYDAQAEVGLRWDDPDLGVDWPVSEPLLSAKDQAALWLRDVPEDRLPVYAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKT1</accession>
    <name>A0A0S2DKT1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phospho-2-dehydro-3-deoxyheptonate aldolase</fullName>
            <ecNumber evidence="3">2.5.1.54</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BV903_22900</name>
        <name evidence="6" type="ORF">FE772_18515</name>
        <name evidence="4" type="ORF">GLE_3763</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">C3</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the class-II DAHP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000077">
        <property type="protein sequence ID" value="OPD61590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948530.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000077.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3763"/>
    <dbReference type="EnsemblBacteria" id="ALN59107">
        <property type="protein sequence ID" value="ALN59107"/>
        <property type="gene ID" value="GLE_3763"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61590">
        <property type="protein sequence ID" value="OPD61590"/>
        <property type="gene ID" value="BV903_22900"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3763"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3707"/>
    <dbReference type="OMA" id="KVMMQMA"/>
    <dbReference type="OrthoDB" id="1371606at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002480">
        <property type="entry name" value="DAHP_synth_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21337">
        <property type="entry name" value="PTHR21337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01474">
        <property type="entry name" value="DAHP_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01358">
        <property type="entry name" value="DAHP_synth_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU363071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD61590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW27335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="463" mass="51965" checksum="AB024586B6E5E652" modified="2016-02-17" version="1">MSASDRSNLRAVNLPADWSPTSWRERTALQLPTYPDQAELESALAELRHLPPLVTSWEILSLKQQLAEAQEGKRFLLQGGDCAESFDQCSSDVISNRLKVLLQMSLVLVHGMRKPVVRVGRFAGQYAKPRSADTETIDGVTLPSYRGDMVNGPAFTEVARKPDPRRMIKAHARSSMTMNFVRALIDGGFADLHHPEYWNLSWVGHSPLADEYRRMVNAIGDAVRFMETLSGAEVHNLNRVDFYTSHEALLLPYEESLTRQVPRHWGHFNLSTHYPWIGMRTAAVDGAHAEYFRGIRNPIALKVGPSVTPDQLLRTIDLLNPEDEPGRLTFIHRMGASTVADKLPPLLDAMRRDGRRVLWVCDPMHGNTESTSNGYKTRRFRNIRAEIEQSFELHAAAGTRLGGVHLELTGEDVTECLGGARELTESDLERAYRSTVDPRLNYEQALEVAMLIVRKQAQIAAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL27</accession>
    <name>A0A0S2DL27_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integral membrane protein, TerC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3927</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3927"/>
    <dbReference type="EnsemblBacteria" id="ALN59269">
        <property type="protein sequence ID" value="ALN59269"/>
        <property type="gene ID" value="GLE_3927"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3927"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3864"/>
    <dbReference type="OMA" id="RMPKHMQ"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005496">
        <property type="entry name" value="Integral_membrane_TerC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03741">
        <property type="entry name" value="TerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="247" mass="26411" checksum="452C2ED774C5F660" modified="2016-02-17" version="1">MPHVMEMLTDPQVWITLFTLSAIEIVLGIDNLVFISIAVSKLPFDQREKARKFGIAVACITRIALLLTLAWLAGLTADLFTVAGIGVSIRDLVLILGGAFLLVKGSMEIKDLIVGEEDADDVHTKPAASFMMVIAQIAVIDIVFSLDSVIAAVGMASHTPVMVAAILLAVGVMLLAARPLGQFIDSNPTIKMLALAFIVLVGAFLILDGLGIHIPKGYIYAAMGFSALVECLNLWAKKRAARRLTAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL40</accession>
    <name>A0A0S2DL40_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">4-diphosphocytidyl-2-C-methyl-D-erythritol kinase</fullName>
            <shortName evidence="9">CMK</shortName>
            <ecNumber evidence="2 9">2.7.1.148</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 11" type="primary">ispE</name>
        <name evidence="12" type="ORF">FE772_18770</name>
        <name evidence="11" type="ORF">GLE_3810</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57823"/>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.148"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 3/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the GHMP kinase family. IspE subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.148" evidence="2 9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057950226.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3810"/>
    <dbReference type="EnsemblBacteria" id="ALN59153">
        <property type="protein sequence ID" value="ALN59153"/>
        <property type="gene ID" value="GLE_3810"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3810"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3753"/>
    <dbReference type="OMA" id="RWPSPAK"/>
    <dbReference type="OrthoDB" id="1938933at2"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00094"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050515">
        <property type="term" value="F:4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00061">
        <property type="entry name" value="IspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004424">
        <property type="entry name" value="IspE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43527:SF2">
        <property type="entry name" value="PTHR43527:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010376">
        <property type="entry name" value="IspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00154">
        <property type="entry name" value="ispE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="5 9 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="10">
        <location>
            <begin position="94"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="102"/>
            <end position="112"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN59153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW27380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="292" mass="30700" checksum="E441CF289E3A784F" modified="2016-02-17" version="1">MSHDFNDPAWSAWPAPAKLNLFLRIVGRRADGYHLLQTVFRLLDWGDTIRLRPRADGRIVRHGGSVAGVAEADDLTVRAALALQTASNCEQGADIVIEKRIPAGGGFGGGSSDAATVLVALDALWGTDLGVEALAELGLRLGADVPVFVRGDNAWAEGVGEDLRPVALAPAWYVLADPGVHAPTAALFRSPELTRDAAPATMSDFVSGRPLGNAFEPVLRQREAAVEAAFAALARIGSPRLTGSGSGCFVEFATRESAEAALAELPPGLRAWTAAGAQRSPLRIALEARRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLC8</accession>
    <name>A0A0S2DLC8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3672</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59016">
        <property type="protein sequence ID" value="ALN59016"/>
        <property type="gene ID" value="GLE_3672"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3672"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="56" mass="6054" checksum="77A2D3D42F4E4CA8" modified="2016-02-17" version="1">MIPGCLLFAHCLALIAERGESSKATQYRLCCDARIAVNAIQMPLHGYERDANASCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLH5</accession>
    <name>A0A0S2DLH5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4064</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4064"/>
    <dbReference type="EnsemblBacteria" id="ALN59406">
        <property type="protein sequence ID" value="ALN59406"/>
        <property type="gene ID" value="GLE_4064"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4064"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4007"/>
    <dbReference type="OMA" id="HTSMIYS"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="197" mass="20542" checksum="115FA2F593F7F559" modified="2016-02-17" version="1">MLHGIWMPGVSMAWLGARLAAAGFQPETFAYAGAAAGPDAVVPKLVESLRRGPAHVLAHSLGGLMTLRALQQHPDLPVRRVVCLGSPLLGSAAADGLSRHAWSAPMLGRAAALLLEGCPPWQGQAQVGLIAGRTPHGLGRWFGRFDGDSDGTVAVAETRLTGLAAHAVIPASHSGLLFSAQAARMTEAFFRRGRFGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM79</accession>
    <name>A0A0S2DM79_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLE_4246</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4246"/>
    <dbReference type="EnsemblBacteria" id="ALN59587">
        <property type="protein sequence ID" value="ALN59587"/>
        <property type="gene ID" value="GLE_4246"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4246"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4187"/>
    <dbReference type="OMA" id="GFAWFQK"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="143"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="8">
        <location>
            <begin position="17"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN59587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="260" mass="28707" checksum="3CAF20233C7E8BE1" modified="2016-02-17" version="1">MFGAAWRYRGFIASSVVNEFKARFSRSTFGALWIILQPLAQVIIFATILSNVLAARLEGVDSKYAYAIYLMSGILCWSLFAEIVQRLQNVFIDNTTLLKKMQFPRIALPVISVGSSLVNNIALLCVVMVILPILGVYPNSHYLWLPLLIALTVALATGVGLIVGVLNVFVRDVGHVMAVLLQFWFWVTPIIYPIKIVPSGFKASLAFNPVAPLAMAYHDVIVYERAPQQSLVMVAVTAAVLLAIAMFLFRRASAEMVDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DME9</accession>
    <name>A0A0S2DME9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fimbrial protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Type 1 fimbrial protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_21645</name>
        <name evidence="2" type="ORF">GLE_4433</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949049.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4433"/>
    <dbReference type="EnsemblBacteria" id="ALN59774">
        <property type="protein sequence ID" value="ALN59774"/>
        <property type="gene ID" value="GLE_4433"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4433"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4370"/>
    <dbReference type="OMA" id="EYYAEDA"/>
    <dbReference type="OrthoDB" id="951513at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009289">
        <property type="term" value="C:pilus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1090">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036937">
        <property type="entry name" value="Adhesion_dom_fimbrial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008966">
        <property type="entry name" value="Adhesion_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039458">
        <property type="entry name" value="FimA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16970">
        <property type="entry name" value="FimA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49401">
        <property type="entry name" value="SSF49401"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726678" evidence="1">
        <location>
            <begin position="22"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="178" mass="18176" checksum="E37ED2AC397539B5" modified="2016-02-17" version="1">MKLFPVLAGVALLAASSAASAYDGTIHFEGSVIAPTCVLTNGPSPADIRVKLPAVAVSALSAAGEVAGRTPFIIRVADCDASTTLVQTFFEPGPTINTSNNNLTLEGGTGTAANVELQVLNADFSQVLLGNPLALQNSQQVAVETGGAALRYYAQYYATDAASAGSANSSVTFTMIYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMP3</accession>
    <name>A0A0S2DMP3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">GNAT family N-acetyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_03310</name>
        <name evidence="4" type="ORF">FE772_21810</name>
        <name evidence="2" type="ORF">GLE_4469</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
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            <end position="170"/>
        </location>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD65335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27890.1"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="170" mass="18719" checksum="BD5E69E20B9B28E4" modified="2016-02-17" version="1">MSRYVTQAAAPEQIGEILALIREHGPNPWNYLPEVELATHLAGIRRGRTQAMIAVADGAIVAVVTFEPSDAFHRYQPAGREIAWQGHVGEAVVHRAHRGQGLGSRLLTAAVARMRAMGLREIYIERHEDNEGSAGMMRKAGFEVIDVYDDPRRRVVGSGRTSVSRLLALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMX2</accession>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
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    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
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</entry>
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            <fullName evidence="1">Uncharacterized protein</fullName>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="GLE_4422"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="72" mass="8174" checksum="CE895D5742659678" modified="2016-02-17" version="1">MRKARASGGVCGGWRAWRCWMCYDGRGNFKARSKWVPAFAGMTRVEVSLPTQRRFGSFVSTSRHSGESRNPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN69</accession>
    <name>A0A0S2DN69_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flagellar assembly protein FliH like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_22615</name>
        <name evidence="2" type="ORF">GLE_4639</name>
    </gene>
    <organism evidence="2 4">
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="GLE_4639"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0969">Cilium</keyword>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="234" mass="24770" checksum="273E3A43B20D67E7" modified="2016-02-17" version="1">MNGVIKAGTVAVSGERRSTVRDLTPASAAVAAPDPQALRIAELEQALAAAQAQLASQAKAAESREKQAFERGRVQGAEAGQAAAQQRYDERVQALTEAVTAAQQRFETQLADVARDWSLQLAQAALARIVGDGSLHAELVARTLAHHLSKLSQDSVLAVEVSAQDFPDADFPDQPALRAALSRHGALPPCRIDADPTRAAGSCVVRLKLGRLDLGLASQRERLDAAFAQLREGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNB9</accession>
    <name>A0A0S2DNB9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_23690</name>
        <name evidence="3" type="ORF">GLE_4878</name>
    </gene>
    <organism evidence="3 5">
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        <lineage>
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    <reference evidence="3 5" key="1">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60219.1"/>
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    </dbReference>
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        <property type="protein sequence ID" value="QCW28200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60219">
        <property type="protein sequence ID" value="ALN60219"/>
        <property type="gene ID" value="GLE_4878"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4878"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4809"/>
    <dbReference type="OMA" id="AYITHAY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033243141" evidence="2">
        <location>
            <begin position="42"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="507" mass="54597" checksum="F808077178D0E1CA" modified="2016-02-17" version="1">MKDRMSAQRNPPPTTFPRPRRRSMPALLLALAVAACAGANAAPRGLEAPAPAATQAATRLSAEDFLAQVGAESQAADDFGRRHLPLQFSGRLDQAVAELVAYAERGGAARRFAVGNMLWAMAPDASLGLHRGADALQPEQPEILFELALHYTRKDDCAAALPLWARLRAGPVGIPATATYAAAYCHLAGGDLRGAVAIVRDSDVDSHHVGAEKMSYEVFGGPSELSLFDRDYRQAAGGDRVALERLLARSFDWHGDWWNAAPQASAQDAAIALARTQWGPRQRERQQWDCLWPKLRDRAQAFGYDDLERCRVIVGGHPPSAHPYPASSALGRVALGRAVARAAQPPDFAALLARHGDTLRGRARSEAGDLEALRVLAYLQQSAGDAAGLAESDELGWKRYRDERFARSRIQHAAPAAGATPDPAYRAMLAQAARDFPHSPLYPMLAAADRAGDGDLFAADLARILQAETRTLDLSVRSGGLRSHSQLKALYRLLDTALEKEGARPGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DND4</accession>
    <name>A0A0S2DND4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo/keto reductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Oxidoreductase, aldo/keto reductase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_15955</name>
        <name evidence="4" type="ORF">FE772_22920</name>
        <name evidence="2" type="ORF">GLE_4711</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000041">
        <property type="protein sequence ID" value="OPD62963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949254.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60052">
        <property type="protein sequence ID" value="ALN60052"/>
        <property type="gene ID" value="GLE_4711"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62963">
        <property type="protein sequence ID" value="OPD62963"/>
        <property type="gene ID" value="BV903_15955"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4711"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4645"/>
    <dbReference type="OMA" id="PYWHQRQ"/>
    <dbReference type="OrthoDB" id="1351747at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="16"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="342" mass="37939" checksum="8E7D1989399EC107" modified="2016-02-17" version="1">MEHRYLGRSGLRVPVLSFGTGTFGGHGDFFKAWGQTDVAEARRLLDIALEAGVNLFDSADIYSRGAAESILGEALQGRPRDSYLISTKATFRFGDGENEVGSSRQHLLRSVDASLKRLGTDYIDLFQLHGFDARTPIEETLSTLDDLVRAGKLRYLGVSNFSGWHLMKSLDLAERHGWSRYVAHQAYYSLIGRDYEWELMPLGLDQGVGAVVWSPLGWGRLTGKIRRGQPLPDTSRLHVTADMGPPVEQEYLYRVVDALDDIAAQTGKTVPQIALNWLLQRPTVATVVIGARNEEQLRQNLGAVGWNLTPEQVATLDAASARDKAYPYWHQAGFAERNPSPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DND6</accession>
    <name>A0A0S2DND6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4703</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60044">
        <property type="protein sequence ID" value="ALN60044"/>
        <property type="gene ID" value="GLE_4703"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4703"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4637"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="39" mass="4595" checksum="657BF49DE16A42AD" modified="2016-02-17" version="1">MLKYRFRGVGAGRKEEAWDDGVDLWIDDLRHRVTTYGDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNE7</accession>
    <name>A0A0S2DNE7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Endo alpha-1,4 polygalactosaminidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_22710</name>
        <name evidence="3" type="ORF">GLE_4660</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949219.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4660"/>
    <dbReference type="EnsemblBacteria" id="ALN60001">
        <property type="protein sequence ID" value="ALN60001"/>
        <property type="gene ID" value="GLE_4660"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4660"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4596"/>
    <dbReference type="OMA" id="STGAWED"/>
    <dbReference type="OrthoDB" id="1327691at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004352">
        <property type="entry name" value="GH114_TIM-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03537">
        <property type="entry name" value="Glyco_hydro_114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242349" evidence="1">
        <location>
            <begin position="23"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_114" evidence="2">
        <location>
            <begin position="45"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="289" mass="31598" checksum="4B49336B9DE67BF4" modified="2016-02-17" version="1">MNKFALIALALAAALCGPGVHAQAPAAVRAEAAAPTWKPLTPGTSWNWQLDGRAANTSMLDGLANPKKMLDIDLDATSAAEVARLKAKGIYVVCYTEVGSYNIQRADAAEFRKVPGLIGKPMDGFEDEYWIDVRMTDALMPIMTARLDKARAKGCDGVEPDLDDSFNQGEENTGFDLTMEDSLHYLQLLVDAAHARGLSMGLKNGPEMAPYAAVFADWALNEECNQHDECGGYKEFIKRNKAVFQVEYRSNGTRLKDFCPADNKNDFDGLLKDASELLRALPRDACRNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNJ4</accession>
    <name>A0A0S2DNJ4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Flavodoxin family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">NADPH-dependent fmn reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_23235</name>
        <name evidence="2" type="ORF">GLE_4775</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949306.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4775"/>
    <dbReference type="EnsemblBacteria" id="ALN60116">
        <property type="protein sequence ID" value="ALN60116"/>
        <property type="gene ID" value="GLE_4775"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4775"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4709"/>
    <dbReference type="OMA" id="SPLYWYS"/>
    <dbReference type="OrthoDB" id="796211at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_red" evidence="1">
        <location>
            <begin position="8"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="209" mass="23624" checksum="FFA50749E700E792" modified="2016-02-17" version="1">MTSDRPRRLLILVASPRRNGNSAALAQAALRGAQDAGLDASLHFADDLMQTFLRDCRDCRDEHGRCRIDDGYADFFFEHFLEADGFALASPVYWYGMSAQAKAFFDRMFCYVARSYPDSQRVRERIQGKRVGLLTASEEMYPTIALSLVNQMQEYARYTHSQFVGAVHGQGDRRGSVAEDRHGAMAAAEALGRQFFERPHADYHVDSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNL8</accession>
    <name>A0A0S2DNL8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4760</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60101">
        <property type="protein sequence ID" value="ALN60101"/>
        <property type="gene ID" value="GLE_4760"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4760"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4693"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="227" mass="24207" checksum="1811F1BC44CBC8C7" modified="2016-02-17" version="1">MLFCAAAACSPAAAAQPSPWRTLSNEDGIHLEARRVAGERFDELRVSTSLKVSPDAVADFLLGKYLDARNKNIRRRFIQRGPEVVVWADVLRTPVADRCYSMRFERQDLADGAVRVKFASLDEAGTGAASDCVALRSRGEWLMTPSAGGTRLVYASLTDIGGNTPVFMAKGPLTSAAVSSVRKVVAGASGWRCRGGWAIERVMTVEGGCASARSAPFSEAIRAAPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNM2</accession>
    <name>A0A0S2DNM2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_21470</name>
        <name evidence="1" type="ORF">GLE_4395</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949018.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59736">
        <property type="protein sequence ID" value="ALN59736"/>
        <property type="gene ID" value="GLE_4395"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4395"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4334"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="138" mass="15122" checksum="60D05C141C0BF8A4" modified="2016-02-17" version="1">MRRRAAALALAFATGGCGVLDSRELWSSGRYVVLWIDAPDQAHLAYRIDDTTTMGLSDPCVSAVAENADYIAVEQRPPQSAQRPLYRLFAKRAPAPRTPAATPLGEPMPQRSYEPLARRLGLPPMQALGVWDACGWEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNV0</accession>
    <name>A0A0S2DNV0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">S-formylglutathione hydrolase</fullName>
            <ecNumber evidence="3 7">3.1.2.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fghA</name>
        <name evidence="9" type="ORF">FE772_23510</name>
        <name evidence="8" type="ORF">GLE_4840</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Serine hydrolase involved in the detoxification of formaldehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>H2O + S-formylglutathione = formate + glutathione + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14961"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="EC" id="3.1.2.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the esterase D family.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.12" evidence="3 7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949352.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4840"/>
    <dbReference type="EnsemblBacteria" id="ALN60181">
        <property type="protein sequence ID" value="ALN60181"/>
        <property type="gene ID" value="GLE_4840"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4840"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4770"/>
    <dbReference type="OMA" id="YFWRRMA"/>
    <dbReference type="OrthoDB" id="1828423at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018738">
        <property type="term" value="F:S-formylglutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046294">
        <property type="term" value="P:formaldehyde catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014186">
        <property type="entry name" value="S-formylglutathione_hydrol"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10061">
        <property type="entry name" value="PTHR10061"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02821">
        <property type="entry name" value="fghA_ester_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0719">Serine esterase</keyword>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR614186-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN60181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW28172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="276" mass="30073" checksum="26C179EE817377BA" modified="2016-02-17" version="1">MEKIESHGCFGGRQQVWSHTATTLGCTMRFGVYLPPQAESADCPVLYWLSGLTCSEQNFITKAGAQRYAAEHGVILVAPDTSPRGEGIPDAEGYDLGIGAGFYLNATRPKWAQHYRMYDYVVDELPALVDAHFPTTSARAISGHSMGGHGALVIALKNPGRYRSVSAFSPIAAPSQSPWGEKAFSAYLGEDREAWTQWDATALVPAAQERLPLLIDQGGDDEFLAAQLKPELLRAACEAAGHPLQLRLRPGYDHSYYFISSFIGEHIAHHAKALRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPE9</accession>
    <name>A0A0S2DPE9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptide synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_22865</name>
        <name evidence="2" type="ORF">GLE_4699</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949245.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4699"/>
    <dbReference type="EnsemblBacteria" id="ALN60040">
        <property type="protein sequence ID" value="ALN60040"/>
        <property type="gene ID" value="GLE_4699"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4699"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4633"/>
    <dbReference type="OMA" id="GERIMYV"/>
    <dbReference type="OrthoDB" id="1068442at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensation" evidence="1">
        <location>
            <begin position="25"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="442" mass="49604" checksum="40A2043EC8D8842B" modified="2016-02-17" version="1">MKRKMMLCERVMYVDRDATFTIVQAARVRGALDPQRLRAALDRVQRKHPMLRCLIEDGDPPTIVREDDPAPIPLRIAERVDAEEWQRQSHLERETRFDSAHAPLIRLTWVRGSDAQGEVGELLLACHHVICDGMSMLTLLREILALCAEPELDIGVHTGFNALADILPAEVINDRRVRRSAGWKALAFRLFFSLRRRRPPVPQGEFFVLHWKLSREDTAALAARAKAEGVTVFAAMSVAFSLAFRTVKGAAATGKIFAPVDVRKFLPLILPDQLFAASPGAIVPLDTELPPERVDDAAFWAQARAFKGRLNQKVERMSRNVHEYFIGLEMMHSIFAQFVAERRSDLDKFDTTISNIGRIDIPQDYPGFRVETVYSPTARLPWRSTTAILSSGYAGELDFVFTCDTASLSREQVDRVRAIAMGLLRERSHAPAADAVPLRAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPJ1</accession>
    <name>A0A0S2DPJ1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5194</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60535">
        <property type="protein sequence ID" value="ALN60535"/>
        <property type="gene ID" value="GLE_5194"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5194"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="50" mass="5476" checksum="6F59B0BBD55583CA" modified="2016-02-17" version="1">MRGLRGGRHGIDAHGRSGGVSTGLGETIPAKIPVRYHLCKTTMNQWFKQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPQ9</accession>
    <name>A0A0S2DPQ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transposase for insertion sequence element</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_4898</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the transposition of the insertion element.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transposase IS30 family.</text>
    </comment>
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    </dbReference>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60239">
        <property type="protein sequence ID" value="ALN60239"/>
        <property type="gene ID" value="GLE_4898"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4898"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4829"/>
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    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
    <dbReference type="GO" id="GO:0003677">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025246">
        <property type="entry name" value="IS30-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001598">
        <property type="entry name" value="Transposase_IS30_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13936">
        <property type="entry name" value="HTH_38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01043">
        <property type="entry name" value="TRANSPOSASE_IS30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="4">
        <location>
            <begin position="188"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="45"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="154"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="353" mass="40561" checksum="5BE93E60242E1F07" modified="2016-02-17" version="1">MGQQYSHLSAEERGAIMVLIAQGASGRQIAQTLGRAQSTIARELRRNGFRSHSGPPLRGRPRFDPGYDATQAGRRAQRLRRRARVRRKLRRDTVLWRRVRYWLERCWSPQQIADKLRDLYPDRPWLRVSHETIYTAIYAMPRGELRRQVTRLLRQGRKSGRRTRQGSDARGHLPDLPNIRLRPPAAHERLMPGHWEGDLIVGAHNRSAIGVLVCRRTLYVKLVKLADATAHTVLEAFSSAFEGVPESLKKTLTYDQGKEMASHRQLSERTGLAIYFADPHSPWQRGTCENTNGLLRQYFPKGTDLSVHSAQRLKEVAWEMNNRPRRSLGRRSPVEVLYEELKNPRAQGDALGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQB1</accession>
    <name>A0A0S2DQB1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5216</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5216"/>
    <dbReference type="EnsemblBacteria" id="ALN60557">
        <property type="protein sequence ID" value="ALN60557"/>
        <property type="gene ID" value="GLE_5216"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5216"/>
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    <dbReference type="OMA" id="WRYQIQW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595571" evidence="1">
        <location>
            <begin position="27"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="331" mass="35144" checksum="81D6FD3E205F4D57" modified="2016-02-17" version="1">MTRRPERMAARACAVVLALAAPAAGAVVLTGEVRSAGAQQIYTPQANTAPVSIRYFVPEGQAVKAGEVVLRIDPGQAGTQIPELDAKIEQARAKSAKELAELEVKAVDAEVALADADAALATAKVEAAIPRGLISQLDYDRHQGDLDKAVREQRLKREQLDAARAAVARRRQDGDLETRKLSVQRDYYAALLRQSEVRAERDGIVLHGFNNNWIGGRIDEGSSTMPGSKAGEVVGSGGAMQVRAWALEPDRPGLRVGQDVRLSFDALPRRELRGRITAIAGAPDRKSEWGEGRYFAIDIDLPAGHGLALLPGMSVRVTAPGAAVGGAGAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQC6</accession>
    <name>A0A0S2DQC6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF1311 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_25695</name>
        <name evidence="3" type="ORF">GLE_5316</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5316"/>
    <dbReference type="EnsemblBacteria" id="ALN60657">
        <property type="protein sequence ID" value="ALN60657"/>
        <property type="gene ID" value="GLE_5316"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5316"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5233"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242242" evidence="2">
        <location>
            <begin position="25"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="280" mass="31075" checksum="5232C2E72DFC2120" modified="2016-02-17" version="1">MFRSHALRAGAALALLAVAGLSQAAGFDCRRARTQVEKTICADAELSRLDSEMNELYRQIRAETRGVDGETGKQVDPIAAENARWLEGRNECRDPACIRSAYQQRIAQMRRDWAQALPQQAPPPAAPAKDKNAYRYDRHGDFKIFIADFRKAVAADDRAAVAKMTARPFADFSHGSSCLPGNDPCDAQQRQQSASARDAAEVAAKYDRILTASVRAALKANRVRAYSRKRDSGEDENGEVQAPGAIEQGEYLLENDDLHGQRVFKRVDGVYKLQRIPFYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQL7</accession>
    <name>A0A0S2DQL7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CMP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">CobQ/CobB/MinD/ParA nucleotide binding domain</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">ParA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_07895</name>
        <name evidence="4" type="ORF">FE772_25085</name>
        <name evidence="2" type="ORF">GLE_5179</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000016">
        <property type="protein sequence ID" value="OPD64460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949611.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5179"/>
    <dbReference type="EnsemblBacteria" id="ALN60520">
        <property type="protein sequence ID" value="ALN60520"/>
        <property type="gene ID" value="GLE_5179"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64460">
        <property type="protein sequence ID" value="OPD64460"/>
        <property type="gene ID" value="BV903_07895"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5179"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5099"/>
    <dbReference type="OMA" id="ADHIAKP"/>
    <dbReference type="OrthoDB" id="1631847at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiA" evidence="1">
        <location>
            <begin position="4"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="209" mass="22912" checksum="DC52EC912E3B0046" modified="2016-02-17" version="1">MKTVLVASSKGGVGKTTIATHLAAQAALEGLRTALIDADPQGSSTRWAQRRSVLESAVLPLDGTRKKAWRKHLPEDAQRAVVDAPAGAMAEDLEAFLDVADAVIVPIQPSTLDIEATVPFLDTLAQHPRIRRGQLRVGLVGNKLKPWTNASQQALELLSEWPYPVVGQIRDSQAYVVMTALGKSLFDYHSQQIREHQADWAPLLKWLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQM3</accession>
    <name>A0A0S2DQM3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_05320</name>
        <name evidence="1" type="ORF">GLE_5428</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000010">
        <property type="protein sequence ID" value="OPD64915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949801.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5428"/>
    <dbReference type="EnsemblBacteria" id="ALN60769">
        <property type="protein sequence ID" value="ALN60769"/>
        <property type="gene ID" value="GLE_5428"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64915">
        <property type="protein sequence ID" value="OPD64915"/>
        <property type="gene ID" value="BV903_05320"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5428"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5344"/>
    <dbReference type="OMA" id="HAEHVND"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019231">
        <property type="entry name" value="DUF2170"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09938">
        <property type="entry name" value="DUF2170"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD64915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="138" mass="14946" checksum="88523A776F5E1EE5" modified="2016-02-17" version="1">MSRWTTQELIARLQATFGAENVEEVPTADAAIQVTLPESGDLGITIALTDREIFVSTPLVESGQVRDAHGFNEACLRLNPINPLSNLGLTTINDRDVYIVFGEMAPDSSAEQIELEIRTLADNAIDAVEALKSYLVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQN2</accession>
    <name>A0A0S2DQN2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA modification GTPase MnmE</fullName>
            <ecNumber evidence="6">3.6.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">trmE</name>
        <name evidence="6" type="synonym">mnmE</name>
        <name evidence="9" type="ORF">GLE_5344</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="6">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer. Heterotetramer of two MnmE and two MnmG subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.-.-" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949736.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5344"/>
    <dbReference type="EnsemblBacteria" id="ALN60685">
        <property type="protein sequence ID" value="ALN60685"/>
        <property type="gene ID" value="GLE_5344"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5344"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5260"/>
    <dbReference type="OMA" id="CEIQCHG"/>
    <dbReference type="OrthoDB" id="263682at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04164">
        <property type="entry name" value="trmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00379">
        <property type="entry name" value="GTPase_MnmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031168">
        <property type="entry name" value="G_TrmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018948">
        <property type="entry name" value="GTP-bd_TrmE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004520">
        <property type="entry name" value="GTPase_MnmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027368">
        <property type="entry name" value="MnmE_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025867">
        <property type="entry name" value="MnmE_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT_dom1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12631">
        <property type="entry name" value="MnmE_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10396">
        <property type="entry name" value="TrmE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00450">
        <property type="entry name" value="mnmE_trmE_thdF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51709">
        <property type="entry name" value="G_TRME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0630">Potassium</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TrmE-type G" evidence="8">
        <location>
            <begin position="219"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="229"/>
            <end position="234"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="248"/>
            <end position="254"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="273"/>
            <end position="276"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="456"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN60685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="456" mass="47636" checksum="54BA9CE647FE2C7D" modified="2016-02-17" version="1">MTASAFARDTIAAIATAPGAGGVGIVRLSGANARAIAETMSGRALRPRHAHYVRFTDAAGDTLDDGIALYFAAPASYTGEDVAELQAHGGPALLEELLARACALGARRARPGEFSERAFLEGRLDLAQAEAVADLIAAADARAARAARRALDGEFSRRVEALAGDLLAVRVHVEAAIDFADEPIDTLGGGALRQRLDAAATTLDELLAAAERGRRLRDGLHAVIVGPPNAGKSSLLNALAGSERAIVTDIAGTTRDLLHETIKLDGVELTLVDTAGLRDGGDAIEREGMRRARGELDRADLAIVVLDARDPHGGLAAVADAIAPVPARLFVYNKIDLLESDYDSPGPADVGGEDRVFVSAHTGAGLDALHARLRALAQGDAGEAMEGAFTARARHVDALIRAGAELDEARVQLDHEMLDLAAESLRQAHDALGEITGRVRADDLLGHIFSSFCIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQN3</accession>
    <name>A0A0S2DQN3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949861.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60862">
        <property type="protein sequence ID" value="ALN60862"/>
        <property type="gene ID" value="GLE_5521"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5521"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5436"/>
    <dbReference type="OrthoDB" id="2103526at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="101" mass="11572" checksum="2A54429237B1FA57" modified="2016-02-17" version="1">MSTPQRRGDHRKIDMSNMSYCKFQNTLSDLIDCRNTVEEMVTGDEGEVFTLSREEARAAENLAEQCFDILTLLCEYAGVEVDQHLDARELMRSVIASLPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA89</accession>
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        <submittedName>
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        </submittedName>
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        <name type="scientific">Lysobacter enzymogenes</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="gene ID" value="GLE_0070"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="DPD_II"/>
    </dbReference>
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        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
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        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006006">
        <property type="entry name" value="GltD-like"/>
    </dbReference>
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        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42783:SF1">
        <property type="entry name" value="PTHR42783:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Fer4_20"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="gltD_gamma_fam"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fer4_20" evidence="2">
        <location>
            <begin position="30"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_2" evidence="1">
        <location>
            <begin position="149"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="510" mass="54686" checksum="7D56C1E6D8485761" modified="2016-02-17" version="1">MSKKQVFQFRDAPREMPSRIPLQLRLDGDWGELYGRFAEVEAKKQAGRCLDCGNPYCGWACPLHNYIPNWLELAREGRLHEAASLCHETNPLPEVCGRVCPQDRLCEGSCTLNDGFGAVTIGAVEKYIVDNALADGWRPDLSAVTASGHRVAIVGAGPAGLSCADRLARAGIQAVVFDRYEHIGGLLHFGIPSFKLEKSVMATRREVLEGMGVQFRLGVEIGRDIAFDALIADYDAVFLGLGTYRYTDGGLPGQDLRHVLPALPFLVQNGRIVHGEGANASSAPIAGWEDHIELPDLRGKRVIVLGGGDTGMDCVRSAVRLGAAQVSCVYRRDEANMPGSAREVANAREEGVQFLFNRQPLELIGDGEAVGGVRVAQTRLGAPDARGRQRAEIVEGSEETLDADVVVIAFGFQPDPPAWLAQQGIELADNGRIKVLATSESCATRRKTAAGLPYQTANPKVFAGGDAVRGADLVVTAAFEGREAAAGIVSLLRERAPLAAARDEKLAKTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAA3</accession>
    <name>A0A0S2DAA3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0107</name>
    </gene>
    <organism evidence="2 3">
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55466">
        <property type="protein sequence ID" value="ALN55466"/>
        <property type="gene ID" value="GLE_0107"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0107"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="39" mass="3998" checksum="C0E80F0BBE89C2C5" modified="2016-02-17" version="1">MTAKFSSTLFRSNFRSAATAANTGSNPPPAINTALESPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAH6</accession>
    <name>A0A0S2DAH6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_0133</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945819.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0133"/>
    <dbReference type="EnsemblBacteria" id="ALN55492">
        <property type="protein sequence ID" value="ALN55492"/>
        <property type="gene ID" value="GLE_0133"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0133"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.136"/>
    <dbReference type="OMA" id="NTAKQWP"/>
    <dbReference type="OrthoDB" id="754526at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
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        <property type="entry name" value="TamB"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="392"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
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            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN55492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1298" mass="137623" checksum="37BDC81EB8FA6E70" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAR1</accession>
    <name>A0A0S2DAR1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">FE772_01060</name>
        <name evidence="2" type="ORF">GLE_0025</name>
    </gene>
    <organism evidence="2 4">
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0025"/>
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        <location>
            <begin position="31"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="69" mass="7558" checksum="2074B687C5277B25" modified="2016-02-17" version="1">MMKITILSWGDWILLSVETAAGKESWLIRRAAPPRPAPAPSRAMTTKPSKPSTGSDPWDELLRSLLGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAX1</accession>
    <name>A0A0S2DAX1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">LysR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_02030</name>
        <name evidence="3" type="ORF">GLE_0240</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="QCW24636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945894.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0240"/>
    <dbReference type="EnsemblBacteria" id="ALN55599">
        <property type="protein sequence ID" value="ALN55599"/>
        <property type="gene ID" value="GLE_0240"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0240"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.242"/>
    <dbReference type="OMA" id="LIEAPCH"/>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="303" mass="33315" checksum="5518A3EE03E8F6EF" modified="2016-02-17" version="1">MNLHLLRVFLTVVEQQGFSRAAEALFVSQSAVSKAVRELENQLDLPLLERTGSDGKAVRGGVHGIALTDHGRAVFEHARAIFALERIATEDVRDRVELRQGRLRIGASTTVAAYWLPQQLGPFVRAHPRLTTELAVANTEEISRAVIDCTVDIGYVEGSVEDPRIAVAHWRDEPLRLVAPADSALGLRRRPSIGELSRQTWLLREPGSGTRQVVQSLFAARGIAPERTMEIGSSEAIARAVVAGVGIALLPATVVADLILMQRVRPIALGEDETLSRPLYRLELANRPRAPALQAFLEYEREH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB59</accession>
    <name>A0A0S2DB59_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutathione S-transferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Glutathione S-transferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_10235</name>
        <name evidence="4" type="ORF">FE772_02875</name>
        <name evidence="2" type="ORF">GLE_0418</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000022">
        <property type="protein sequence ID" value="OPD64082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946020.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000022.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0418"/>
    <dbReference type="EnsemblBacteria" id="ALN55776">
        <property type="protein sequence ID" value="ALN55776"/>
        <property type="gene ID" value="GLE_0418"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64082">
        <property type="protein sequence ID" value="OPD64082"/>
        <property type="gene ID" value="BV903_10235"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0418"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.415"/>
    <dbReference type="OMA" id="FERSPDR"/>
    <dbReference type="OrthoDB" id="1383885at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="8"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="223" mass="24733" checksum="F53909D7CB518104" modified="2016-02-17" version="1">MTPTITAFETSPDRGKGLARDMRVRWALEELGQPYRVRLLSFAAMKQPAHLALHPFGQIPTYEDGGLALFESGAIVLHLAERHPGLLPADADARMRAIAWMFAALNTVEPPIFERAMTEVLERERSWYAERAAMLDERVHRRLGELSRHLGDADWLDGGFSAGDLLMTTVLLRLARFGTVEAYPNLAGYLARATARPAYQRAFAAQREVFEQSQAAAEGASPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBD7</accession>
    <name>A0A0S2DBD7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_10230</name>
        <name evidence="4" type="ORF">FE772_02870</name>
        <name evidence="2" type="ORF">GLE_0417</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000022">
        <property type="protein sequence ID" value="OPD64081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946019.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000022.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55775">
        <property type="protein sequence ID" value="ALN55775"/>
        <property type="gene ID" value="GLE_0417"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64081">
        <property type="protein sequence ID" value="OPD64081"/>
        <property type="gene ID" value="BV903_10230"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0417"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.414"/>
    <dbReference type="OMA" id="ASKITAC"/>
    <dbReference type="OrthoDB" id="2158710at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594808" evidence="1">
        <location>
            <begin position="28"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="256" mass="26820" checksum="DAD1F99AFD80A79C" modified="2016-02-17" version="1">MKWFSAPTLVLLAAIGLIQLSGATAQAVTPPFVLNPALCAPVCGASQLADRSWIKPGRAIYEEQSVDVDIDAADLLQAGQESVFVSTLSGDQAFTPAGQFTANATGGGIGIVLGSAQPPYHPNCVGATAQNRQFGIFGYTWAAPWASTPGVMDCKNIPKAALSRGTTVRVSIDTYCGRGLAPVCSVTATLTNKATGAVLAQSSVSGVRIKNPLNARKVWYGVSNFYADAPNYPVSFTPKVETYYAEIEPQCNPICP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBG1</accession>
    <name>A0A0S2DBG1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tyrosine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Tyrosyl-tRNA synthetase</fullName>
            <shortName evidence="8">TyrRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">tyrS</name>
        <name evidence="11" type="ORF">FE772_02140</name>
        <name evidence="10" type="ORF">GLE_0265</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + H(+) + L-tyrosyl-tRNA(Tyr)</text>
            <dbReference type="Rhea" id="RHEA:10220"/>
            <dbReference type="Rhea" id="RHEA-COMP:9706"/>
            <dbReference type="Rhea" id="RHEA-COMP:9707"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78536"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.1" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945913.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0265"/>
    <dbReference type="EnsemblBacteria" id="ALN55624">
        <property type="protein sequence ID" value="ALN55624"/>
        <property type="gene ID" value="GLE_0265"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0265"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.265"/>
    <dbReference type="OMA" id="YMMAKDS"/>
    <dbReference type="OrthoDB" id="402899at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004831">
        <property type="term" value="F:tyrosine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006437">
        <property type="term" value="P:tyrosyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00805">
        <property type="entry name" value="TyrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02007">
        <property type="entry name" value="Tyr_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002307">
        <property type="entry name" value="Tyr-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024088">
        <property type="entry name" value="Tyr-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024108">
        <property type="entry name" value="Tyr-tRNA-ligase_bac_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766">
        <property type="entry name" value="PTHR11766"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766:SF1">
        <property type="entry name" value="PTHR11766:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01040">
        <property type="entry name" value="TRNASYNTHTYR"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00234">
        <property type="entry name" value="tyrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="232"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN55624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW24653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="409" mass="44809" checksum="056092FD10621296" modified="2016-02-17" version="1">MSTSVQEALDLIARGADEIIKIEELEARLTASMKAGGRPLRIKAGFDPTAPDLHLGHTVLLNKMRQFQDLGHQVIFLIGDFTGMIGDPSGKNATRKALTREDVLANAETYAEQVFKVLDKDRTEVRFNSEWFGKMGAADMIRLAAQHTVARMLERDDFAKRYAGQQPIAIHEFLYPLVQGYDSVALQCDVELGGTDQKFNLLMGRGLQEHHGQPAQIVLTMPLLEGLDGVNKMSKSLGNYIGVNEPAIDIVTKAMKIDDALMWRWIDLLSFEISIAEAARLKQEIEAGQLNPRDLKLRLARELAARFHGADAAELAVAGWNAAVRGEGDLSSLPLTDVAVPAEGLRIAALLTAAGLTPSNSEANRKLKERAVKVDGHVVEDAQRVFAPGFEGVLTVGRRTFARVRLVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBJ1</accession>
    <name>A0A0S2DBJ1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Linear gramicidin synthetase subunit C</fullName>
            <ecNumber evidence="7">5.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_0544</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="5.1.1.-" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946113.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0544"/>
    <dbReference type="EnsemblBacteria" id="ALN55902">
        <property type="protein sequence ID" value="ALN55902"/>
        <property type="gene ID" value="GLE_0544"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0544"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.538"/>
    <dbReference type="OMA" id="AFEWVER"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043604">
        <property type="term" value="P:amide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="1006"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="983"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1041"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN55902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1118" mass="122932" checksum="4C80BAC7D554A979" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBP7</accession>
    <name>A0A0S2DBP7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 12">Epoxyqueuosine reductase QueH</fullName>
            <ecNumber evidence="5 12">1.17.99.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 12">Queuosine biosynthesis protein QueH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">queH</name>
        <name evidence="14" type="ORF">FE772_03600</name>
        <name evidence="13" type="ORF">GLE_0580</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">C3</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 12">Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>AH2 + epoxyqueuosine(34) in tRNA = A + H2O + queuosine(34) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:32159"/>
            <dbReference type="Rhea" id="RHEA-COMP:10345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10346"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:82831"/>
            <dbReference type="ChEBI" id="CHEBI:82834"/>
            <dbReference type="EC" id="1.17.99.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the QueH family.</text>
    </comment>
    <dbReference type="EC" id="1.17.99.6" evidence="5 12"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946139.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0580"/>
    <dbReference type="EnsemblBacteria" id="ALN55938">
        <property type="protein sequence ID" value="ALN55938"/>
        <property type="gene ID" value="GLE_0580"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0580"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.573"/>
    <dbReference type="OMA" id="PNIHPYT"/>
    <dbReference type="OrthoDB" id="1078220at2"/>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052693">
        <property type="term" value="F:epoxyqueuosine reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02089">
        <property type="entry name" value="QueH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003828">
        <property type="entry name" value="QueH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36701">
        <property type="entry name" value="PTHR36701"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02677">
        <property type="entry name" value="QueH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9 12" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="12" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0819">tRNA processing</keyword>
    <feature type="binding site" evidence="12">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="12">
        <location>
            <begin position="184"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN55938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW24890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="230" mass="26224" checksum="8255C511D767E329" modified="2016-02-17" version="1">MSAPRPPVSLPDGAQRLLLHSCCAPCSGEVMEALLAAGIDYTIFFYNPNIHPVKEYELRKDENVRFADKHGVPFVDADYDTDNWFARARGMENEPERGIRCTMCFDMRFERTALYAHEHGFAAISSSLGISRWKNMEQINDCGHRAAARYPGLSYWDYNWRKGGGSQRMVEISKRERFYQQEYCGCVYSLRDTNRQRKAQGRGRIKIGLVYYGDEAAAPAPADRTDPADT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBV9</accession>
    <name>A0A0S2DBV9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Efflux ABC transporter, permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLE_0656</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0656"/>
    <dbReference type="EnsemblBacteria" id="ALN56014">
        <property type="protein sequence ID" value="ALN56014"/>
        <property type="gene ID" value="GLE_0656"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0656"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.645"/>
    <dbReference type="OMA" id="LIMWRLS"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038766">
        <property type="entry name" value="Membrane_comp_ABC_pdt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30287">
        <property type="entry name" value="PTHR30287"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="303"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="412"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="458"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="705"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="754"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="789"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="283"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="734"/>
            <end position="816"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="828" mass="87832" checksum="F020D44F87FDEFAD" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC01</accession>
    <name>A0A0S2DC01_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Bifunctional protein GlmU</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="15">UDP-N-acetylglucosamine pyrophosphorylase</fullName>
                <ecNumber evidence="15">2.7.7.23</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="15">N-acetylglucosamine-1-phosphate uridyltransferase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="15">Glucosamine-1-phosphate N-acetyltransferase</fullName>
                <ecNumber evidence="15">2.3.1.157</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="15 17" type="primary">glmU</name>
        <name evidence="17" type="ORF">GLE_0692</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:13509"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="EC" id="2.7.7.23"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>acetyl-CoA + alpha-D-glucosamine 1-phosphate = CoA + H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13725"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="ChEBI" id="CHEBI:58516"/>
            <dbReference type="EC" id="2.3.1.157"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="15">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="15">Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="15">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route II): step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="15">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; UDP-N-acetyl-alpha-D-glucosamine from N-acetyl-alpha-D-glucosamine 1-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">In the C-terminal section; belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.23" evidence="15"/>
    <dbReference type="EC" id="2.3.1.157" evidence="15"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0692"/>
    <dbReference type="EnsemblBacteria" id="ALN56050">
        <property type="protein sequence ID" value="ALN56050"/>
        <property type="gene ID" value="GLE_0692"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0692"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.680"/>
    <dbReference type="OMA" id="TAIVEHK"/>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00532"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00973"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019134">
        <property type="term" value="F:glucosamine-1-phosphate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003977">
        <property type="term" value="F:UDP-N-acetylglucosamine diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03353">
        <property type="entry name" value="LbH_GlmU_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01631">
        <property type="entry name" value="GlmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005882">
        <property type="entry name" value="Bifunctional_GlmU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038009">
        <property type="entry name" value="GlmU_C_LbH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01173">
        <property type="entry name" value="glmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 15 17" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10 15" id="KW-0133">Cell shape</keyword>
    <keyword evidence="14 15" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6 15 17" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11 15" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 15 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transf_3" evidence="16">
        <location>
            <begin position="12"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyrophosphorylase" evidence="15">
        <location>
            <begin position="1"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-GlcNAc binding" evidence="15">
        <location>
            <begin position="14"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-GlcNAc binding" evidence="15">
        <location>
            <begin position="85"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-GlcNAc binding" evidence="15">
        <location>
            <begin position="107"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Linker" evidence="15">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-acetyltransferase" evidence="15">
        <location>
            <begin position="254"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Acetyl-CoA binding" evidence="15">
        <location>
            <begin position="389"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="366"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="230"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="336"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="354"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="369"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="380"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="383"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="408"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="426"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="443"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF12804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ALN56050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="461" mass="49088" checksum="9731010F58F7A6BB" modified="2016-02-17" version="1">MAHESMNQLHIVILAAGEGKRMKSATAKVLQKIAGRPMLAHVIDTARALRPAGIHLVYGHGGEQVRAAFAGQDDLHWSEQEQRLGTGHAVQQAMPGVPQDARVLVLYGDVPLIAAPTLQRLLDAPGRLAVLVADLDDPTGYGRIVRDPEGRVGRIVEHKDADEDERAIRTVNTGILVADGEPLRRWLDRLGNDNAQGEYYLTDVFASAAAEYSPAEMVHVDDPIEVEGANDPWQLAQLERAFQRRAARALCVQGARLADPARYDQRGTVTVGRDVEIDVDAILEGTVELGDGVRIGPFCRLKDVRLGAGTEVRAHCDLDGVTVEGAAQIGPYARLRPGTVLADGAHVGNFVETKNARVGVGSKANHLTYLGDAVIGAGVNVGAGTITCNYDGVNKWVTTIEDGAFIGSNSSLVAPVTIGKDATIAAGSTITRPAPAGELSIGRARQATVEGWKRPVKKPKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC85</accession>
    <name>A0A0S2DC85_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Cardiolipin synthase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="14">Phospholipase D Active site motif</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">cls</name>
        <name evidence="15" type="ORF">FE772_04390</name>
        <name evidence="14" type="ORF">GLE_0741</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">C3</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946263.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56099">
        <property type="protein sequence ID" value="ALN56099"/>
        <property type="gene ID" value="GLE_0741"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0741"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.729"/>
    <dbReference type="OrthoDB" id="1881748at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008808">
        <property type="term" value="F:cardiolipin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032049">
        <property type="term" value="P:cardiolipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022924">
        <property type="entry name" value="Cardiolipin_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027379">
        <property type="entry name" value="CLS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13396">
        <property type="entry name" value="PLDc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04265">
        <property type="entry name" value="bac_cardiolipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="13">
        <location>
            <begin position="232"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="13">
        <location>
            <begin position="410"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN56099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW25023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="497" mass="54558" checksum="3D24AC0F08BA9A48" modified="2016-02-17" version="1">MSLDLTWLPTALNLGLTGFVFAAHLLIAARALTRPNRTPASRAAWVAVIMLAPVAGMVAYLLLGETNIGRARVDRIEHAGKRMPSPDDAANAPSAVPDHAAPLFELARSINGFHAVGGNRIALLGDEDSAADDPKRDCRLAIDALVADIEQARESVHIAFYIWLDDGAGGRVADAVADAARRGVACRVMVDAFGSRAFIAGERWKQLGGAGVKLLRTLDDLNRLQHIAFSRMDLRDHRKIVVIDNKIAYCGSQNCADAEFRIKPAYAPWIDLLLRCEGPVVRQTQFLFLSGWIPETGETGLDDYPDAATPQRFDEDCIAQAFETGPVVRHNAMSDMFAACIYAARRELTIVTPYFVPDESILRAICAAPRRGAATRLVFPQRNDSWFVGQTCRSTYADLLRAGVEVYEYPLGILHTKAMCIDGEVALVGSANMDRRSLDLNFENNLVIADRALVAAIRRRQDKYLSVSHRVALDEVEAWPLRVRLVQNAVAMMSPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCC7</accession>
    <name>A0A0S2DCC7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">3-isopropylmalate dehydratase large subunit</fullName>
            <ecNumber evidence="12">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Alpha-IPM isomerase</fullName>
            <shortName evidence="12">IPMI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12 15" type="primary">leuC</name>
        <name evidence="15" type="ORF">GLE_0818</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 12">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterodimer of LeuC and LeuD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="12"/>
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        <property type="protein sequence ID" value="ALN56176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="ALN56176"/>
        <property type="gene ID" value="GLE_0818"/>
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    <dbReference type="KEGG" id="lez:GLE_0818"/>
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        <property type="component" value="Chromosome"/>
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        <property type="match status" value="1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="leuC"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="8 12" id="KW-0408">Iron</keyword>
    <keyword evidence="9 12" id="KW-0411">Iron-sulfur</keyword>
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    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
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        <location>
            <begin position="3"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="401"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="404"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ALN56176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="467" mass="49474" checksum="86843054C673B578" modified="2016-02-17" version="1">MFDKLWNAHLVAPESEAAPAVLYIDLHLIHEVTSPQAFAELEARGLGPRRPDLTKGTLDHSTPTLPAGADGRLPYYTAEAEHQVDTLRRNCARHGVELFDYDSAHRGIVHVIGPELGLTQPGQTIVCGDSHTATHGAFGALAFGIGTSEVGHVLATQCLLQRKPKTLAINVEGELAPGVGAKDLILHIIGAIGVNGGTGHVIEYRGSTIRALSMDERMTVCNMSIEAGARAGLIAPDRVTFDYLAATPRAPRGADWDRAVARWSAFKTDDGAAFDREVHIDAGAIKPTLTWGTHPGQVAAIDARLPQADDADEAKALAYMGFDGGAPMAGRPVDVVFVGSCTNSRLSDLRQAAQVLRGRRVHPRVRMLVVPGSEQVKRDAEAEGIDAVVRAAGAEWREPGCSMCIAMNGDLVGAGQLAVSTSNRNFEGRQGKGARTLLASPLTAAACAVAGHVVDPREYLTDVKEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCH3</accession>
    <name>A0A0S2DCH3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lytic metalloendopeptidase</fullName>
            <ecNumber evidence="2">3.4.24.32</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_09635</name>
        <name evidence="4" type="ORF">FE772_04835</name>
        <name evidence="2" type="ORF">GLE_0833</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.24.32" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD64139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946330.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000021.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56191">
        <property type="protein sequence ID" value="ALN56191"/>
        <property type="gene ID" value="GLE_0833"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64139">
        <property type="protein sequence ID" value="OPD64139"/>
        <property type="gene ID" value="BV903_09635"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0833"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.822"/>
    <dbReference type="OMA" id="ATNYYHM"/>
    <dbReference type="OrthoDB" id="613527at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000841">
        <property type="entry name" value="Pept_M23A_Blytic"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00933">
        <property type="entry name" value="BLYTICPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594829" evidence="1">
        <location>
            <begin position="27"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="377" mass="40334" checksum="FAA3FBF2B8FC13EC" modified="2016-02-17" version="1">MKTISKAGLGLALCCALAAIGGTANAQGQGLQGEDLVYSYDEMFDFDIDAYLAKRAPHLRKHSEEISHWAGYSGISPKVLIALMEQQSGAVSAKRAPARPFGKLARADGFGAQTREVALALRESLYERDPDGAKGPVTLARANPLQALFERSGDNEPAAALRGDGEFQLVYGRLFNEARQAKAPSDRFAKAGPDVQPLSPNGLLQFPFPRGASWHVGGAHTNTGSGNYPMSSLDMSRGGGWGSNQNGNWVSASAAGSFKRHSSCFAEIVHSGGWSTTYYHLMNIQYNTGANVSMNTAIANPANTQAQALCNGGSSTGPHEHWSLKQNGSFYHLNGTYLSGYRITATGSSYDTNCSRFYLTKGGQNYCYGYYTNPGPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCM3</accession>
    <name>A0A0S2DCM3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_04340</name>
        <name evidence="2" type="ORF">GLE_0730</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946255.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0730"/>
    <dbReference type="EnsemblBacteria" id="ALN56088">
        <property type="protein sequence ID" value="ALN56088"/>
        <property type="gene ID" value="GLE_0730"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0730"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.718"/>
    <dbReference type="OMA" id="YAWRNHA"/>
    <dbReference type="OrthoDB" id="2029688at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031347">
        <property type="entry name" value="AmpE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17113">
        <property type="entry name" value="AmpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="304" mass="32551" checksum="2EE38D587721FE46" modified="2016-02-17" version="1">MSVTLIAAVVALVLGHLAQSLAASLRHFGWYDDWLRWIDSRFPEGSFWRGRWGIVIALLPPLLAVGLFQLALVEPLIGLGGLVFAIFILFYAWGPRDLDLDVEALASARDGASRREAAARLWPDGATPALDGGSLVEAVFRSALRRWFGVLFWFLVLGPIGALGYRLAALAAEGEASRRLPGETLAGARTLLALLDWPVAQLLTLAMALVGNFDTVLGAWREAGGASFSLDNRFLGAVARASVKCELAEEAADYVNESGVPDQAVAVAAGGEVPELRDAMSLVWRSLLVWLAVLALFVIAGFVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCP6</accession>
    <name>A0A0S2DCP6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BlaI/MecI/CopY family transcriptional regulator</fullName>
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        <name type="scientific">Lysobacter enzymogenes</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BlaI transcriptional regulatory family.</text>
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        <property type="protein sequence ID" value="ALN56309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="69.GLE_0951"/>
    <dbReference type="EnsemblBacteria" id="ALN56309">
        <property type="protein sequence ID" value="ALN56309"/>
        <property type="gene ID" value="GLE_0951"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0951"/>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25177.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="123" mass="14058" checksum="F6915C9607E7A5FF" modified="2016-02-17" version="1">MQISEAESVVMEVLWQRHPLAAEEVAAAVADAQSWQEATVKTLLNRLLNKGAIRAEKDGRRYLYAPVLKREDWLLDESQGLLQRLFGGRVAPLVAHFSQHRKLSRKDIAELRKLLEELDDDAR</sequence>
</entry>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <dbReference type="EMBL" id="ALN56314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="39" mass="3636" checksum="C8757BE8EE891140" modified="2016-02-17" version="1">MAVVGGAVGGAVGEPECRGAWAVVGGPSGPMLLSQIAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD26</accession>
    <name>A0A0S2DD26_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_05985</name>
        <name evidence="2" type="ORF">GLE_1085</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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            <taxon>Gammaproteobacteria</taxon>
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    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="gene ID" value="GLE_1085"/>
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            <end position="333"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="436"/>
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            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="436" mass="47171" checksum="29532B431A2DD66B" modified="2016-02-17" version="1">MPTPAETLETLLADFERGNPSAGANLRSLIETTPELETRMLTAIGDGHLDKFKPLDPALRARGILGGFDSKDDSIALPIDVLEASGADPRKANTLRMVFGHEIEHSIHKTDIARTAESTKQEIARIAGSPSPHDYTDVLRNHNDNARLREANDQIAGFNVLAAHVRRENPDATPEQLNEKLYASAPQMRQYFDVGLDADGKQTYAPKPGLTIGANGQIAVNANNIEAMGTYFYDRNRYPELYTQRNLGEAYRAEQEAAKADPSRPTPEVKVDLQALKLPGLALPPGFSDSSPALAPPAPRAPPESAPRPAEPATRSPFLDPSARSPDEPSGNDRAYFQMVRDRLPEQVPDHAVAHAVLQAKRGGLEADQVDPGKIGLHDGKIWIGANTPGFHVSVDPKQAPPMEQVQRELQTLPSAQPAAPAVATEEVQSPGGRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDA6</accession>
    <name>A0A0S2DDA6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF1304 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_06005</name>
        <name evidence="2" type="ORF">GLE_1090</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
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    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1090"/>
    <dbReference type="EnsemblBacteria" id="ALN56448">
        <property type="protein sequence ID" value="ALN56448"/>
        <property type="gene ID" value="GLE_1090"/>
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            <end position="27"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="99"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="116" mass="12784" checksum="BBF315AD5EFE2FDD" modified="2016-02-17" version="1">MPWLAVVLTALVAVLHTWFLVLEMFLWTKPLGMKTFRMNPEKAEQTKVLAANQGLYNGFLVAGLVWALVCARQDVATFFLACVVVAGVFGAATVSRRIFYVQAVPAIAALAAWWLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDG7</accession>
    <name>A0A0S2DDG7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribosomal subunit interface protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Ribosome-associated translation inhibitor RaiA</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="primary">raiA</name>
        <name evidence="3" type="ORF">BV903_16385</name>
        <name evidence="5" type="ORF">D9T17_21170</name>
        <name evidence="4" type="ORF">FE772_06475</name>
        <name evidence="2" type="ORF">GLE_1191</name>
    </gene>
    <organism evidence="2 6">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">C3</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 9" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000043">
        <property type="protein sequence ID" value="OPD62856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000053">
        <property type="protein sequence ID" value="ROU04953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946585.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000053.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1191"/>
    <dbReference type="EnsemblBacteria" id="ALN56549">
        <property type="protein sequence ID" value="ALN56549"/>
        <property type="gene ID" value="GLE_1191"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62856">
        <property type="protein sequence ID" value="OPD62856"/>
        <property type="gene ID" value="BV903_16385"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1191"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1176"/>
    <dbReference type="OMA" id="NLTGHHI"/>
    <dbReference type="OrthoDB" id="2088581at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00552">
        <property type="entry name" value="RaiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036567">
        <property type="entry name" value="RHF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003489">
        <property type="entry name" value="RHF/RaiA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02482">
        <property type="entry name" value="Ribosomal_S30AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69754">
        <property type="entry name" value="SSF69754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00741">
        <property type="entry name" value="yfiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU04953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="111" mass="12580" checksum="829DF33C64F366D9" modified="2016-02-17" version="1">MRIETHGQQIEVTPALRDYVESKLARLQRHYDQPFDVRTQLSLDKPDHRAEATLNLAGRTLHCDAAAVDMYAAIDLLADKLDRLLMKHKSKLVDHHRGESLARNGEIGEIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDM9</accession>
    <name>A0A0S2DDM9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2-methylisocitrate lyase</fullName>
            <shortName evidence="3">2-MIC</shortName>
            <shortName evidence="3">MICL</shortName>
            <ecNumber evidence="3">4.1.3.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">(2R,3S)-2-methylisocitrate lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">prpB</name>
        <name evidence="6" type="ORF">FE772_06930</name>
        <name evidence="5" type="ORF">GLE_1288</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.</text>
    </comment>
    <comment type="function">
        <text evidence="3">Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate</text>
            <dbReference type="Rhea" id="RHEA:16809"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57429"/>
            <dbReference type="EC" id="4.1.3.30"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Organic acid metabolism; propanoate degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 3 4">Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.30" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946661.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1288"/>
    <dbReference type="EnsemblBacteria" id="ALN56645">
        <property type="protein sequence ID" value="ALN56645"/>
        <property type="gene ID" value="GLE_1288"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1288"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1271"/>
    <dbReference type="OMA" id="VKDLAPW"/>
    <dbReference type="OrthoDB" id="1485205at2"/>
    <dbReference type="UniPathway" id="UPA00946"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046421">
        <property type="term" value="F:methylisocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019629">
        <property type="term" value="P:propionate catabolic process, 2-methylcitrate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00377">
        <property type="entry name" value="ICL_PEPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01939">
        <property type="entry name" value="PrpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039556">
        <property type="entry name" value="ICL/PEPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018523">
        <property type="entry name" value="Isocitrate_lyase_ph_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012695">
        <property type="entry name" value="PrpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02317">
        <property type="entry name" value="prpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00161">
        <property type="entry name" value="ISOCITRATE_LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="45"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="122"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="209"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW25438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="293" mass="31965" checksum="5CB4AA298DF5E658" modified="2016-02-17" version="1">MSQLSAGAKFRAALAAESPLQVMGAITAYAGLMAKRTGYKALYLSGGGVAANSLGMPDLGISTMEDVLTDARRIVDATGMPLLVDIDTGWGGAFNIGRTIRNFERIGVAAVHMEDQVGQKRCGHRPGKEVVSKDEMVDRVKAAVDGRTDDQFVIMARTDAAAVEGIDSAIERAVAYVEAGADMIFPEAMKTLDDYRRFKAAVKVPILANLTEFGSTPFFTTDELREAGVDIALYCCGAYRAMNKAALNFYETVRREGTQKNIVDTLQTRADLYDFLGYHEYEDKLDRLFAQNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDN1</accession>
    <name>A0A0S2DDN1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1274</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946648.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1274"/>
    <dbReference type="EnsemblBacteria" id="ALN56631">
        <property type="protein sequence ID" value="ALN56631"/>
        <property type="gene ID" value="GLE_1274"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1274"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1257"/>
    <dbReference type="OrthoDB" id="1748687at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595025" evidence="2">
        <location>
            <begin position="21"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="255" mass="25029" checksum="C4D593741CD434B1" modified="2016-02-17" version="1">MRLSPVLALLTAAALAAALAACGGKDAAAGGDGTAAGDPAALPTPEGGGRGGITGMPDAGQPGPAGAPAAAAPLDENGNPLPPADPAALPTDPDAVAANDPALPVPAGADPANADAASASQPAADGAATAAEPTPEDAVAVVRDYYAAINSRNYGRAYALWSDGGRASGQDAQQFANGFANTAGVSVELAPPGRVDAGAGQRHIEVPVSITATQRDGSQRRYVGGYTLRRTVVDGASAEQRAWRIASADIRELKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDP8</accession>
    <name>A0A0S2DDP8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Calpain catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_06770</name>
        <name evidence="4" type="ORF">GLE_1253</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25406.1"/>
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    <keyword evidence="1" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="3">
        <location>
            <begin position="1"/>
            <end position="303"/>
        </location>
    </feature>
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            <begin position="94"/>
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        </location>
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        </location>
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        </location>
    </feature>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
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        </location>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="ALN56688.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="61" mass="6687" checksum="FC292F634E3CD9AE" modified="2016-02-17" version="1">MDAIAGQYFHRRKLQVVRGSDEDTLASRHCGKDRLGCTGAAGPSGAGNRDRLGRRRLWAAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE64</accession>
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        </submittedName>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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            <begin position="37"/>
            <end position="59"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="140" mass="14398" checksum="50DCDB4D0961566F" modified="2016-02-17" version="1">MKNAIFAVAGALAGLAIQAAGMQLTLAALLSGWDGPFSGGGLFAATTLLLLLLPTGVCAGAVARRYLFLVPALLLLAVGWEMYLGISGDVADTIAGNLDVLDLVDGLTLFLWAAMALSIGIVQGCRLSWRAWPKPVAKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEC7</accession>
    <name>A0A0S2DEC7_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="3" type="ORF">FE772_07875</name>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW25595.1"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56858">
        <property type="protein sequence ID" value="ALN56858"/>
        <property type="gene ID" value="GLE_1501"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1501"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1482"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="185" mass="19052" checksum="F3E11F7F412B53BB" modified="2016-02-17" version="1">MAAAPSAAKTEPLSECERGRLAARKTGGCGLVGMLACVASIGGIFPLVVVALEPEGLSWGAAVAIAFAVVCGLGLIAFVTANADDRVEADAAAGIKLIVTGRVVQMPTDSSDGGPPSRCLWVVVDGGASRPLIFQADEALYRAVRIDDAVRIAYVPNSMTIIQLRTAGYEYSICDDGEAGEKRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEU6</accession>
    <name>A0A0S2DEU6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Protease HtpX</fullName>
            <ecNumber evidence="12">3.4.24.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Heat shock protein HtpX</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12 16" type="primary">htpX</name>
        <name evidence="15" type="ORF">BV903_23890</name>
        <name evidence="16" type="ORF">FE772_09290</name>
        <name evidence="14" type="ORF">GLE_1811</name>
    </gene>
    <organism evidence="14 17">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">C3</strain>
        </source>
    </reference>
    <reference evidence="15 18" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 18">B25</strain>
        </source>
    </reference>
    <reference evidence="16 19" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 19">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell membrane</location>
            <topology evidence="12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the peptidase M48B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="12"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000087">
        <property type="protein sequence ID" value="OPD61401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947064.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000087.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1811"/>
    <dbReference type="EnsemblBacteria" id="ALN57163">
        <property type="protein sequence ID" value="ALN57163"/>
        <property type="gene ID" value="GLE_1811"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61401">
        <property type="protein sequence ID" value="OPD61401"/>
        <property type="gene ID" value="BV903_23890"/>
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    <sequence length="304" mass="32471" checksum="A8017552136341A4" modified="2016-02-17" version="1">MFKRIALFLATNLAVLVLLGIVMSVLQNVFGIRLGNNGAILVMAAVFGFGGSLISLLMSKWVAKKSTGAYVIEQPRNETEQWLVSTVRRQAEAAGIGMPEVAIYDAPEINAFATGANRNNSLVAVSTGLIRAMTRDEAEAVLAHEVSHVANGDMVTMALIQGVLNTFVLVAARIVGGWIDAMMSGNREGGGRGLFYFVTVFALDIVFGLLASMIAMAFSRYREFRADAGGARLAGREKMIAALKRLSLTYGESTLPNQVQAFGISGAVGHGLSKLMRSHPPLEERIQALIDAPQERASGSAVVR</sequence>
</entry>
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</entry>
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    <accession>A0A0S2DF09</accession>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
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            </authorList>
        </citation>
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        </source>
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        <property type="entry name" value="ABC_TRANSPORTER_2"/>
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    </dbReference>
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        <location>
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        <ligand>
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        <source>
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    </evidence>
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        <source>
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            <dbReference type="PROSITE" id="PS50929"/>
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        <source>
            <dbReference type="EMBL" id="ALN57090.1"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW25774.1"/>
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    </evidence>
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    </evidence>
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    </evidence>
    <sequence length="598" mass="63665" checksum="A104E16287BE57DD" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF19</accession>
    <name>A0A0S2DF19_LYSEN</name>
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        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="27"/>
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            <begin position="28"/>
            <end position="73"/>
        </location>
    </feature>
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            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="73" mass="7815" checksum="FCF843FA14F39EF4" modified="2016-02-17" version="1">MSLRKPTALAALAVAVFGFAASLTASAQIDQCERCRVVWEDCLLHAENQAQTQACDRAYGQCMSPIDCPAPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFL1</accession>
    <name>A0A0S2DFL1_LYSEN</name>
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        <submittedName>
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        <submittedName>
            <fullName evidence="13">Isovaleryl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BV903_10900</name>
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    </gene>
    <organism evidence="12 15">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">C3</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">B25</strain>
        </source>
    </reference>
    <reference evidence="14 17" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
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    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="OPD63906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="QCW25954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947181.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1974"/>
    <dbReference type="EnsemblBacteria" id="ALN57324">
        <property type="protein sequence ID" value="ALN57324"/>
        <property type="gene ID" value="GLE_1974"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63906">
        <property type="protein sequence ID" value="OPD63906"/>
        <property type="gene ID" value="BV903_10900"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1974"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="term" value="P:organonitrogen compound catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
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        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
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        <property type="entry name" value="AcylCo_DH-like_C"/>
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        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF00441">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0274">FAD</keyword>
    <keyword evidence="3 8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="8"/>
            <end position="119"/>
        </location>
    </feature>
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        <location>
            <begin position="123"/>
            <end position="220"/>
        </location>
    </feature>
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        <location>
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            <end position="380"/>
        </location>
    </feature>
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        <location>
            <begin position="181"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
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        </location>
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        <location>
            <begin position="124"/>
            <end position="133"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
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        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
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        <location>
            <begin position="158"/>
            <end position="160"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
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        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="339"/>
            <end position="343"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="368"/>
            <end position="370"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR634183-1"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU362125"/>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN57324.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="OPD63906.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW25954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="385" mass="41455" checksum="28197F8DF009DBC3" modified="2016-02-17" version="1">MRSFPLGEEIDALRDAVRRFAEAEIAPRAEQIDHDNAFPQDLWPKLGEMGLLGMTVPGEFGGSEMGYLAHLVAMEEISRASGSIGLSYGAHSNLCVSNLFANGNQAQRAKYLPKLCSGEWKGALAMSEPGAGSDVVGSMSCRAELRDGVWVANGNKMWITNGPEADVLLVYMRTAGKDAGSKCMTAFIVEKGMKGFSTAQKLDKLGMRGSNTCELVFENCEIPAENVVGEVNQGVKVLMSGLNTERLVLTGGPLGLMQSAMDIALPYVRERKQFDAAIGTFGLMQGKIADMYTSLQSSRAFAYQVARDFDSGYKSRVDAASCLLHASDAAVEVALEAIQTLGGNGYINEYPTGRILRDAKLYAIGAGTNEIRRMLIGRELFDGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFP6</accession>
    <name>A0A0S2DFP6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF853 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_10750</name>
        <name evidence="3" type="ORF">GLE_2128</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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        </lineage>
    </organism>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
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    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="7"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="230" mass="24380" checksum="88CA18247E70DB22" modified="2016-02-17" version="1">MSGKPTIVLVHGFWGGAAHWAKTIVELSRKGYTDLRAVEIPLTSLADDAARTRKMIEQAPGPVLLVGHSYGGAVITEAGNHDKVAGLVYIAAFAPDSGESPGGITQEHLPEAAPNLAPDSDGYLWLKADKFHESFCQDLSAEEGLVMAVTQKAPLASTFGDAISTPAWKSKPTWYQISAHDRMIAPQNQQRMSARMNPNKTITLEASHASLASKPAEVAALIGEAAKAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGJ1</accession>
    <name>A0A0S2DGJ1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NADH-quinone oxidoreductase subunit I</fullName>
            <ecNumber evidence="6">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">NADH dehydrogenase I subunit I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">NDH-1 subunit I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 11" type="primary">nuoI</name>
        <name evidence="10" type="ORF">BV903_08645</name>
        <name evidence="12" type="ORF">D9T17_13305</name>
        <name evidence="11" type="ORF">FE772_10935</name>
        <name evidence="8" type="ORF">GLE_2167</name>
        <name evidence="9" type="ORF">LEN_2872</name>
        <name evidence="13" type="ORF">SAMN05421681_10484</name>
    </gene>
    <organism evidence="8 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 14">C3</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2016" name="DNA Res." volume="0" first="0" last="0">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer, Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M497-1</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="3">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">ATCC 29487</strain>
        </source>
    </reference>
    <reference evidence="9 17" key="4">
        <citation type="journal article" date="2017" name="DNA Res." volume="24" first="169" last="177">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
            <dbReference type="PubMed" id="28065880"/>
            <dbReference type="DOI" id=".1093/dnares/dsw055"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 17">M497-1</strain>
        </source>
    </reference>
    <reference evidence="10 16" key="5">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 16">B25</strain>
        </source>
    </reference>
    <reference evidence="12 18" key="6">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 18">OH11</strain>
        </source>
    </reference>
    <reference evidence="11 19" key="7">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 19">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 2 [4Fe-4S] clusters per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the complex I 23 kDa subunit family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP014940">
        <property type="protein sequence ID" value="BAV98359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000018">
        <property type="protein sequence ID" value="OPD64361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000033">
        <property type="protein sequence ID" value="ROU06429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNOG01000004">
        <property type="protein sequence ID" value="SDX16807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947332.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2167"/>
    <dbReference type="EnsemblBacteria" id="ALN57517">
        <property type="protein sequence ID" value="ALN57517"/>
        <property type="gene ID" value="GLE_2167"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAV98359">
        <property type="protein sequence ID" value="BAV98359"/>
        <property type="gene ID" value="LEN_2872"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64361">
        <property type="protein sequence ID" value="OPD64361"/>
        <property type="gene ID" value="BV903_08645"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDX16807">
        <property type="protein sequence ID" value="SDX16807"/>
        <property type="gene ID" value="SAMN05421681_10484"/>
    </dbReference>
    <dbReference type="KEGG" id="lem:LEN_2872"/>
    <dbReference type="KEGG" id="lez:GLE_2167"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2130"/>
    <dbReference type="OMA" id="RGDLYYT"/>
    <dbReference type="OrthoDB" id="1619561at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000183696">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000218824">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050136">
        <property type="term" value="F:NADH dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01351">
        <property type="entry name" value="NDH1_NuoI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010226">
        <property type="entry name" value="NADH_quinone_OxRdtase_chainI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10849">
        <property type="entry name" value="PTHR10849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01971">
        <property type="entry name" value="NuoI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0874">Quinone</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="6 9" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="53"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="93"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN57517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAV98359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD64361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW26109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROU06429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDX16807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000183696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000218824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="162" mass="18638" checksum="D13233CC71208DC3" modified="2016-02-17" version="1">MNRIVSYFKSLLLIELAQGLGLTLKYLFKPKYTLMYPMEKTPQSPRFRGVHALRRYPNGEERCIACKLCEAVCPALAITIDSEKRADGTRRTTRYDIDLFKCIFCGFCEESCPVDSIVETHIHEYHFDQRGQNIVTKPQLLAIGDRLETEIAERRAADAAFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGQ1</accession>
    <name>A0A0S2DGQ1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Chaperone protein DnaJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 14" type="primary">dnaJ</name>
        <name evidence="15" type="ORF">FE772_11255</name>
        <name evidence="14" type="ORF">GLE_2233</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">C3</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 2 Zn(2+) ions per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="9">The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DnaJ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947385.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2233"/>
    <dbReference type="EnsemblBacteria" id="ALN57582">
        <property type="protein sequence ID" value="ALN57582"/>
        <property type="gene ID" value="GLE_2233"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2233"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2198"/>
    <dbReference type="OMA" id="DLHCTVT"/>
    <dbReference type="OrthoDB" id="1738789at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="SSF49493"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="SSF57938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02349">
        <property type="entry name" value="DnaJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0677">Repeat</keyword>
    <keyword evidence="7 9" id="KW-0346">Stress response</keyword>
    <keyword evidence="6 9 10" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="12">
        <location>
            <begin position="5"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="13">
        <location>
            <begin position="133"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="9">
        <location>
            <begin position="146"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="9">
        <location>
            <begin position="162"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="9">
        <location>
            <begin position="184"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="9">
        <location>
            <begin position="198"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="10">
        <location>
            <begin position="133"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN57582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW26161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="377" mass="40915" checksum="1497F93116D5328D" modified="2016-02-17" version="1">MSKRDYYEVLGVQRNASDDDLKKAYRRCAMKFHPDRNPGDQAAEASFKECKEAYEVLSDASKRRVYDQHGHAAFEHGMGGGGAGPGFADMGDIFGDIFGNIFGGGGGGGARGPRRGADIGYVMELSLEEAVGGVEKQIEIPTLDECETCKGSGSADGKIETCTTCNGRGQVRFQRGIFSMQQACPHCNGRGQTIANPCGDCHGQGRVERTKTLQVKIPAGVDNGDRIRLTGEGEAGPTGSPPGDLYVEVRVREHEIFQRDGDDLHCEVPIRISQAALGDIVRVPTLGGEVELRIPAETQSGKLFRLRDKGVKSVRSRKPGDLYCRVAVETPVNLTVEQRELLEKFEATFVGEGARKHSPRSSTFIDGVKGFWDRMTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGT5</accession>
    <name>A0A0S2DGT5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4166 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2211</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2211"/>
    <dbReference type="EnsemblBacteria" id="ALN57560">
        <property type="protein sequence ID" value="ALN57560"/>
        <property type="gene ID" value="GLE_2211"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2211"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2173"/>
    <dbReference type="OMA" id="IWTRLYA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025311">
        <property type="entry name" value="DUF4166"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13761">
        <property type="entry name" value="DUF4166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4166" evidence="2">
        <location>
            <begin position="64"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="245" mass="27814" checksum="2A57ED02E6EB6287" modified="2016-02-17" version="1">MQRIDLPAQTGANAAAPATADRPATGRREHKRPETQAPAAAGLEPAHDLAALLKAALGPRWALLHPHIRARFELAAGQAQAEYVGDMHQVRCTRLGALFARLIRYARVLPHHNADDVPFRFDVEPLRRELGWIKTRTYHFAQEIFSFRSRMTLGAGGELLEHFGGGLGMRVRLEVLPNRLVFVDDGYFLHWRGLRLPLPRPLWPGRFVLVHRDLDAEQFEVCIDVAHPWFGPLFHQEGRFQRLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGY5</accession>
    <name>A0A0S2DGY5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_12680</name>
        <name evidence="1" type="ORF">GLE_2524</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947606.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2524"/>
    <dbReference type="EnsemblBacteria" id="ALN57873">
        <property type="protein sequence ID" value="ALN57873"/>
        <property type="gene ID" value="GLE_2524"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2524"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2486"/>
    <dbReference type="OrthoDB" id="491477at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="375" mass="41171" checksum="27CE679E59DE932F" modified="2016-02-17" version="1">MAEIAETADTPVREVAILCSGVALGVYLPGLEIARRLRSHGVRGRVFVLEAFQPADVEDALIRARERHQRDFRALRMSQQLVRDISPTLDAAALAALAARLDAAGTTHLLALSGFWLPWAAAYARERAHCTLEALHIDSVPSPSWLPYAQRPEFAQAAHRYFIDRAAPRAAFRLEIGEAAPVAHAQRPPELLLHGGGWSVGTFASAVDDVLAAGYRASIVRGSAADLQPREGVRNLLLDPQWRAWRDTGPEQLGEFPRLGFADADGELRYRQSDAVPDLFEITRASLAVVSKPGGSTLIDSMAAATPVLFLAPSGKHEQANAEAWIALGYGAWFEQWREDGAQREALERMHARLLRDRAQVPEYCRQLAAELDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGZ6</accession>
    <name>A0A0S2DGZ6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TetR/AcrR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_12800</name>
        <name evidence="4" type="ORF">GLE_2551</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947629.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57900">
        <property type="protein sequence ID" value="ALN57900"/>
        <property type="gene ID" value="GLE_2551"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2551"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2511"/>
    <dbReference type="OMA" id="FMATVHG"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="18"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="206" mass="22444" checksum="454170DB544C79C7" modified="2016-02-17" version="1">MKPTASKRSASDPQAPPSPKAEEILQRTSELLALGGYDSFSYADIAEQVQVRKASIHHHFPSKVDLVKATVARHRESSRRGLQALSERVADPFDRLGEYCRWWAACIESANPPICLCALLAAELPSVPVEVASEVRGHFEDLSAWLEQTLAQGADSGRLRLTASAHAEAMTFMAAVHGAMLTARALGDARLFWSIAQASLERLRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH04</accession>
    <name>A0A0S2DH04_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2485"/>
    <dbReference type="EnsemblBacteria" id="ALN57834">
        <property type="protein sequence ID" value="ALN57834"/>
        <property type="gene ID" value="GLE_2485"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2485"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2447"/>
    <dbReference type="OMA" id="HQPPISL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070290">
        <property type="term" value="F:N-acylphosphatidylethanolamine-specific phospholipase D activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024884">
        <property type="entry name" value="NAPE-PLD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038896">
        <property type="entry name" value="NAPE-PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="104"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="373" mass="41151" checksum="E91B7DFF5C40D3BD" modified="2016-02-17" version="1">MSICLPFAAKPRLSSADHASHANRAASPQFADGRFHNVVPRPPTGVRKMLRIIADALWNKPADAVPAVAPAVRPLTARQLARAPDRSLYRLGHSTVLVKLRGGWWITDPVFAQRASPLQWIGPKRFHAPPIALADLPPLRGVILSHDHFDHLDRATVLRLAKTAGVFLTPLGVGDRLIGWGVDPAKVRQFDWWQGTCIDGVRFVATPAQHFSGRGLLDGDKTLWASWTILDESGDGDTLRLFFSGDTGYFAGFAEIGRRFGPFDVTLLETGAYDANWPHVHMQPEQTVQAHLDLRGRWLLPIHNGTFDLALHPWTEPFERVSALAAQRGVALSTPRMGERVDLRAPAATAPWWREADAAEPFSTDLTEQESAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH10</accession>
    <name>A0A0S2DH10_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_2567</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2567"/>
    <dbReference type="EnsemblBacteria" id="ALN57916">
        <property type="protein sequence ID" value="ALN57916"/>
        <property type="gene ID" value="GLE_2567"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2567"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2526"/>
    <dbReference type="OMA" id="ASGYFEF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="70"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="337"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="342"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="367" mass="38322" checksum="50CDDE744770786B" modified="2016-02-17" version="1">MNSTTACLLLAGATALLCACSQQKPATPRAPESVRAVTVARVESRALASAASASGLLVAREEAAVGVEQAGVRVLRVLVEEGARVRAGQPLAVLDDALLRERLAQARAQAAQAGSEAERVRGLDGSGVMSEEEIGRRRSQARIAQAQLRELETQSRQTTVRAPVSGVVIERSARPGSLSGGEPLFRIVRDDQVELDAEVPETAILGIEPGQPVAVTLADGQVFAGRVRLVSPRIDPKTKLGRVRVALPVDADLRVGGFARAAFAGRSAPVATVPEKAVHFEASGPQLTLIDRDDRARRVAVKTGRRSGGVVELLQGPPVGSRVALAGGAFLIDGDRVRPEPVVPEPVAPEPVAPTPHAPKPASAAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH73</accession>
    <name>A0A0S2DH73_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_11725</name>
        <name evidence="2" type="ORF">GLE_2339</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947464.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57688">
        <property type="protein sequence ID" value="ALN57688"/>
        <property type="gene ID" value="GLE_2339"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2339"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2301"/>
    <dbReference type="OrthoDB" id="2167834at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242222" evidence="1">
        <location>
            <begin position="29"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="161" mass="15870" checksum="EAB0AA1B8D32CA16" modified="2016-02-17" version="1">MDYAIRAKLFAAVAALGLGLLAAPHADAASQCKTLKLLPGVVQVYATVDGAAAGDSAFCTADFACPTGSTKVEVFGTALATTRDAVIAVDNTANLSSGEQVSSNCIATVVGNGKRVSVSTCNAKAEAPANKGTADTSACSVYAESPAGARVGANATCFCGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH80</accession>
    <name>A0A0S2DH80_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_02275</name>
        <name evidence="4" type="ORF">FE772_12005</name>
        <name evidence="2" type="ORF">GLE_2398</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000004">
        <property type="protein sequence ID" value="OPD65609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947511.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57747">
        <property type="protein sequence ID" value="ALN57747"/>
        <property type="gene ID" value="GLE_2398"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65609">
        <property type="protein sequence ID" value="OPD65609"/>
        <property type="gene ID" value="BV903_02275"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2398"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2360"/>
    <dbReference type="OMA" id="TYHIERT"/>
    <dbReference type="OrthoDB" id="2036081at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045752">
        <property type="entry name" value="DUF6180"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19678">
        <property type="entry name" value="DUF6180"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595561" evidence="1">
        <location>
            <begin position="22"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD65609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="129" mass="13301" checksum="D4DBEC5F9F5EEE13" modified="2016-02-17" version="1">MRIASVSILCIGLALPLSAAAADFSLGYEVDRVPAAQLSVQACNAAIGRGAAALGYVVRANQDQKTLSLHVSGPRQEGRSLVAYCIAAGNHTAWVVQAFDYSGPGLSEPGVIAKKVAGEIRKAIKPAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHI3</accession>
    <name>A0A0S2DHI3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aminoglycoside 4'-O-nucleotidyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2537</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57886">
        <property type="protein sequence ID" value="ALN57886"/>
        <property type="gene ID" value="GLE_2537"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2537"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2499"/>
    <dbReference type="OrthoDB" id="702172at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012481">
        <property type="entry name" value="KNTase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002934">
        <property type="entry name" value="Polymerase_NTP_transf_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07827">
        <property type="entry name" value="KNTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01909">
        <property type="entry name" value="NTP_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transf_2" evidence="1">
        <location>
            <begin position="48"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="KNTase_C" evidence="2">
        <location>
            <begin position="153"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="293" mass="31945" checksum="723178F46812F7F9" modified="2016-02-17" version="1">MMENQMMENRTMEHALPNGSELPNGRLDDIFSGPQAVAADERSALSARVVESVRERFGEHLQHLVLYGSTGRGEDRPHSDIDLWGIVSDELYGAQFQKAIEWVYGPGKILVMLFSRTMAEAVAREVDESWPITRAKFLHSRLVWASPGNENLLAELRAIAANPDPERAGRAMAGIISGTLYELMGKLRNRSAPHAMIAGTFAMHLALVTGLGARYAYTTFGAVLREALNLPGPDGAQELYAMVLSGELSDIARVEAVVERAWAGLSSWQAGPAFTAALQRRVSHTFGSLEAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHN3</accession>
    <name>A0A0S2DHN3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Deoxyribodipyrimidine photolyase</fullName>
            <ecNumber evidence="9">4.1.99.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">phrB</name>
        <name evidence="9" type="ORF">GLE_2636</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA photolyase class-1 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DNA photolyase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.3" evidence="9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947694.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2636"/>
    <dbReference type="EnsemblBacteria" id="ALN57984">
        <property type="protein sequence ID" value="ALN57984"/>
        <property type="gene ID" value="GLE_2636"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2636"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2595"/>
    <dbReference type="OMA" id="WQWSASS"/>
    <dbReference type="OrthoDB" id="184000at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003904">
        <property type="term" value="F:deoxyribodipyrimidine photo-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901363">
        <property type="term" value="F:heterocyclic compound binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097159">
        <property type="term" value="F:organic cyclic compound binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051716">
        <property type="term" value="P:cellular response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018394">
        <property type="entry name" value="DNA_photolyase_1_CS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="PTHR11455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="SSF48173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="SSF52425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00394">
        <property type="entry name" value="DNA_PHOTOLYASES_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0157">Chromophore</keyword>
    <keyword evidence="5 7" id="KW-0274">FAD</keyword>
    <keyword evidence="4 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="8">
        <location>
            <begin position="6"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN57984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="476" mass="54185" checksum="A7D9EABC5C9EA4EE" modified="2016-02-17" version="1">MPEAQPSALVWFRDDLRLDDNPALRAALEAGFVPVPVYIHAPDEHGAWAPGAASDAWRHHSLAALDADLRKRGSHLRRFFGPSLATLQSLALATGAQAVFWNRRYEPYIEKRDTRIKQQLRRTGLEAESFNGSLLFEPWTLRTKQGGPFKVFTPFWRAALADWREHPAWQAPASLPATREGPEGVPLDALRLLPKLGWDREFWQHWSPGEAGARAALETFVDGALRGYAEQRDRPDRVGTSRLSPHLHFGEIAPWRAVAALQAERNAGNARDVDAAIRELGWREFAHHLLHHFPDTPEQNFNPRFADFDWARAAPPKLEPWQQGRTGVPIVDAGMRELWATGWMHNRVRMIVASYLTKHLRLHWRHGARWFWDTLVDADLANNTLGWQWVAGTGADAAPYFRVFNPVTQSEKFDPDGAYIARWVPELAGLPVPLRFAPWQDPRRLRREAPDYPPQPLVDLAAGRDAALEAYRRLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHZ9</accession>
    <name>A0A0S2DHZ9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF58 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947716.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2665"/>
    <dbReference type="EnsemblBacteria" id="ALN58013">
        <property type="protein sequence ID" value="ALN58013"/>
        <property type="gene ID" value="GLE_2665"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2665"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2624"/>
    <dbReference type="OMA" id="ARDDHLY"/>
    <dbReference type="OrthoDB" id="848990at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF58" evidence="1">
        <location>
            <begin position="40"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="297" mass="32941" checksum="1C6467FB44C097D2" modified="2016-02-17" version="1">MRDLIPADVRARLRSLSLVSRRAVGAHGIGAHRSRSRGAGLEFAQYRAYEPGDELRQVDWKLYARSDRFFVREAERESPLAVWLLLDASASMDQRDGARPDYPRLDAAKAIAACVAELALRQNDRFGLMVLREDGLRMLPPATGARQRDRLLLELHGLRAHGAWPAPASLRPLWERIGAGDLVLMLGDGLDEAALAVAERLAAARREVLSVRILTVEERDFPFRGGHRFRDPETGEELLGDGAALRREFIERFGAARRAVDARLDAAGVRHAEHTLDEPVDLPLRRLFGARDAAAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI26</accession>
    <name>A0A0S2DI26_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF2845 domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Transcriptional regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_14180</name>
        <name evidence="2" type="ORF">GLE_2840</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947851.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58188">
        <property type="protein sequence ID" value="ALN58188"/>
        <property type="gene ID" value="GLE_2840"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2840"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2798"/>
    <dbReference type="OrthoDB" id="2065724at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242210" evidence="1">
        <location>
            <begin position="20"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="88" mass="9559" checksum="79F0AF778E5708DE" modified="2016-02-17" version="1">MRQIFAFLLFAALSTAALAQAVAFGNKLVSVGDPVGRVFEVAGQPSRTVPVENKFGAREGERLEYFVGNKTVLITVRDGKVTQVQEVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI56</accession>
    <name>A0A0S2DI56_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58158">
        <property type="protein sequence ID" value="ALN58158"/>
        <property type="gene ID" value="GLE_2810"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2810"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="105" mass="11726" checksum="2D6240F72FF1EE13" modified="2016-02-17" version="1">MLSLRRRGGRRSRRRGGRRRLGGRRGRSRLTAYHQGHGDHQCAMGRILHADLAGERRVRWGCCITLACNGCDGAALRPYASTSANALASAAYQPSFDQREIGRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIH0</accession>
    <name>A0A0S2DIH0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphoserine aminotransferase</fullName>
            <ecNumber evidence="8">2.6.1.52</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Phosphohydroxythreonine aminotransferase</fullName>
            <shortName evidence="8">PSAT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">serC</name>
        <name evidence="12" type="ORF">FE772_14925</name>
        <name evidence="11" type="ORF">GLE_2984</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4-phosphooxybutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:16573"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58452"/>
            <dbReference type="ChEBI" id="CHEBI:58538"/>
            <dbReference type="EC" id="2.6.1.52"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8 9">
            <text>2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:14329"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57524"/>
            <dbReference type="EC" id="2.6.1.52"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
        <text evidence="8">Binds 1 pyridoxal phosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 8 9">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 3/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.52" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947959.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2984"/>
    <dbReference type="EnsemblBacteria" id="ALN58332">
        <property type="protein sequence ID" value="ALN58332"/>
        <property type="gene ID" value="GLE_2984"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2984"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2945"/>
    <dbReference type="OMA" id="GYRASMY"/>
    <dbReference type="OrthoDB" id="996960at2"/>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00197"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00244">
        <property type="reaction ID" value="UER00311"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004648">
        <property type="term" value="F:O-phospho-L-serine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00160">
        <property type="entry name" value="SerC_aminotrans_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022278">
        <property type="entry name" value="Pser_aminoTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43247">
        <property type="entry name" value="PTHR43247"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000525">
        <property type="entry name" value="SerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01364">
        <property type="entry name" value="serC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 9 11" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6 8" id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8 9" id="KW-0718">Serine biosynthesis</keyword>
    <keyword evidence="8 9 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="10">
        <location>
            <begin position="5"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="8">
        <location>
            <begin position="76"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="8">
        <location>
            <begin position="237"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN58332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW26746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="361" mass="39253" checksum="59488383B4FC90E3" modified="2016-02-17" version="1">MSRAFNFSAGPATLPEPVLLQAQSELLEWNNAGASIVELSHRGPEFIQVAAEAERDLRALMAIPDDYAVLFLQGGATAQQALIALNFANPGQAVDYVVTGHWGKTALKQVKPYVSANVAANGEAGGFRDIPARADWNLSKDVAYVHYTANETIHGVEFRDIPDVGDVPLVADFSSSIAAEPIDVSKFGVIYAGAQKNLGPVGVSVVIVRRDLLERAGQPRADIFDYRSHVKGESMLNTPPTWNWYLAGLVFKWMLAEGGVEEFAQRNARKAGLLYDVIDNSGGYYRNEVAVAARSRMNVPFFLKDEALDKPFLKEAEAAGLISLKGHRALGGMRASIYNAMPEAGVQALASFMRDFQQRHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIH3</accession>
    <name>A0A0S2DIH3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Histidinol-phosphate aminotransferase</fullName>
            <ecNumber evidence="6">2.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Imidazole acetol-phosphate transaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hisC</name>
        <name evidence="9" type="ORF">FE772_14915</name>
        <name evidence="8" type="ORF">GLE_2982</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>2-oxoglutarate + L-histidinol phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23744"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="2.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.9" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947957.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2982"/>
    <dbReference type="EnsemblBacteria" id="ALN58330">
        <property type="protein sequence ID" value="ALN58330"/>
        <property type="gene ID" value="GLE_2982"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2982"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2943"/>
    <dbReference type="OMA" id="NYHVAGF"/>
    <dbReference type="OrthoDB" id="1248286at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00012"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004400">
        <property type="term" value="F:histidinol-phosphate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01023">
        <property type="entry name" value="HisC_aminotrans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005861">
        <property type="entry name" value="HisP_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01141">
        <property type="entry name" value="hisC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 6 8" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="7">
        <location>
            <begin position="49"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW26744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="385" mass="41040" checksum="9F8DCFFBE1FDB026" modified="2016-02-17" version="1">MSQPAPLAAAPAFDEAWFAARAQPGVQRLKAYDPGHDLVALRRQYGEAHLVELGSNENPYGPSPAARAAILDSLHALHRYPDPLGGDLKRALARTHGVEVGQILLGNGSHELLMQLGQVFAGPGEEVVFSRYGFAVFALSTQAAGARMRIVEALPREAAMPCGHDLDAIAAAVGADTKLVYVANPNNPTGTWFGRDALVAFLDKIPAHVIVVMDEAYAEMADAPDYASALSVLDRYPNVAVTRTFSKAYGLAGLRVGYLIAQPGLIAVMDRLRESFNVNGPALAACEAALGDEDHLRWACARNAEQRSALAEALARRGLRVFPSQTNFVLVEFGARTPQVEAALVARGVILRPMGGYGLADCIRISVGSADENRRLLAALDEVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIU1</accession>
    <name>A0A0S2DIU1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-phosphoshikimate 1-carboxyvinyltransferase</fullName>
            <ecNumber evidence="7">2.5.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">5-enolpyruvylshikimate-3-phosphate synthase</fullName>
            <shortName evidence="7">EPSP synthase</shortName>
            <shortName evidence="7">EPSPS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">aroA</name>
        <name evidence="10" type="ORF">BV903_02995</name>
        <name evidence="9" type="ORF">GLE_2981</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">B25</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21256"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="EC" id="2.5.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the EPSP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.19" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000005">
        <property type="protein sequence ID" value="OPD65500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947956.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000005.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2981"/>
    <dbReference type="EnsemblBacteria" id="ALN58329">
        <property type="protein sequence ID" value="ALN58329"/>
        <property type="gene ID" value="GLE_2981"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65500">
        <property type="protein sequence ID" value="OPD65500"/>
        <property type="gene ID" value="BV903_02995"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2981"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2942"/>
    <dbReference type="OMA" id="YEDHRMA"/>
    <dbReference type="OrthoDB" id="533829at2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00089"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003866">
        <property type="term" value="F:3-phosphoshikimate 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01556">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00210">
        <property type="entry name" value="EPSP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006264">
        <property type="entry name" value="EPSP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023193">
        <property type="entry name" value="EPSP_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000505">
        <property type="entry name" value="EPSPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="SSF55205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01356">
        <property type="entry name" value="aroA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00104">
        <property type="entry name" value="EPSP_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00885">
        <property type="entry name" value="EPSP_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="EPSP_synthase" evidence="8">
        <location>
            <begin position="15"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate-3-phosphate binding" evidence="7">
        <location>
            <begin position="28"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoenolpyruvate" evidence="7">
        <location>
            <begin position="99"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="322"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="350"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="349"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="353"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="394"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN58329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD65500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="439" mass="45235" checksum="11CBC62FDF072F8E" modified="2016-02-17" version="1">MSASESSQAWTAGPGAALRGSIRVPGDKSVSHRAVMLGALAEGVTRVTGFLEGEDTRATARVFEQLGVRIETPSASERIVHGVGLHGLRGSDAALDCGNAGTGMRLLAGALAGQAFDSVLVGDASLSKRPMRRVTEPLAAMGARIDSEDGGLPPLRIRGGRELRGIEYTLPVASAQVKSALLLAGLYAQGETVVREPHPTRDYTERMLAAFGWPIEFSPGHARLSGGHALRATDVAVPADFSSAAFFLVAASVVPGSELVLEAVGMNPRRTGLLSALRLMGADIVEENPRSEGGEPVADLRVRHARLRGVEVPQALVPDMIDEFPALFVAAAVAQGRTVVSGAAELRVKESDRIATMAAGLRALGVAIEETPDGAIIDGGGLSGGAVESHGDHRIAMSFAVAAQLATGEVRIGDVANVATSFPGFEALAAQAGMRVGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIV7</accession>
    <name>A0A0S2DIV7_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_15510</name>
        <name evidence="3" type="ORF">GLE_3115</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_3115"/>
    <dbReference type="EnsemblBacteria" id="ALN58462">
        <property type="protein sequence ID" value="ALN58462"/>
        <property type="gene ID" value="GLE_3115"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3115"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3072"/>
    <dbReference type="OMA" id="VGAPKRY"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
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    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
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    </dbReference>
    <dbReference type="Pfam" id="PF03372">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
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    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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            <begin position="1"/>
            <end position="24"/>
        </location>
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            <begin position="25"/>
            <end position="290"/>
        </location>
    </feature>
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        <location>
            <begin position="48"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="290" mass="31600" checksum="EBEA8C32F273CAD1" modified="2016-02-17" version="1">MSGARARWRAGVCVMLAAALAACAAPQRASAPQAAQANDAQAREVRVLTLNLWHDKGDWPRRRALILAEVARLKPDLIALQEVLQRPGLRNQAQDLGEALGYRVGFVSVDPPDAPRRYGNAILIAGTGSDAQQRKLEPLDDYRSAAHVRSDKADVDFYATHLHNERGGGAIRARQVASLLAFVDASAHGARTLIAGDFNTEADAPELAALRARYADAFATAHPRLAADPARASTLNPAYLPAQRIDHVFYDRRGFAVKEARIVLNESRDGVWPSDHFGLFVRLQPLPAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIY1</accession>
    <name>A0A0S2DIY1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF2147 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_15710</name>
        <name evidence="3" type="ORF">GLE_3160</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948087.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58506">
        <property type="protein sequence ID" value="ALN58506"/>
        <property type="gene ID" value="GLE_3160"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3160"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3116"/>
    <dbReference type="OMA" id="CTDARKD"/>
    <dbReference type="OrthoDB" id="1848240at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019223">
        <property type="entry name" value="DUF2147"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09917">
        <property type="entry name" value="DUF2147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242313" evidence="1">
        <location>
            <begin position="20"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2147" evidence="2">
        <location>
            <begin position="25"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="146" mass="15916" checksum="32C83D3ADEAC490E" modified="2016-02-17" version="1">MRKQLLALLLLALPVAAFAQATPVGSWTTIDDKTQKPKSVVEIYEAKDGSLAGRVNEVLQSEHGPNPVCDKCDGERKGKPVKGMVILWGIRKSGDTWEGGKILDPASGKVYSVKVTPQDGGKKLEVRGFMGFSLIGRSQTWMRHEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ65</accession>
    <name>A0A0S2DJ65_LYSEN</name>
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        <recommendedName>
            <fullName evidence="4">Catalase</fullName>
            <ecNumber evidence="4">1.11.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FE772_16075</name>
        <name evidence="14" type="ORF">GLE_3240</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">C3</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 H2O2 = 2 H2O + O2</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 12">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the catalase family.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948147.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3240"/>
    <dbReference type="EnsemblBacteria" id="ALN58586">
        <property type="protein sequence ID" value="ALN58586"/>
        <property type="gene ID" value="GLE_3240"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3240"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3193"/>
    <dbReference type="OMA" id="WTCYVQV"/>
    <dbReference type="OrthoDB" id="1584770at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08156">
        <property type="entry name" value="catalase_clade_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040333">
        <property type="entry name" value="Catalase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024711">
        <property type="entry name" value="Catalase_clade1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002226">
        <property type="entry name" value="Catalase_haem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465">
        <property type="entry name" value="PTHR11465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038928">
        <property type="entry name" value="Catalase_clade1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF56634"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00437">
        <property type="entry name" value="CATALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="9 12" id="KW-0408">Iron</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 14" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase" evidence="13">
        <location>
            <begin position="14"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR038928-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR038928-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN58586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW26926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="487" mass="55407" checksum="042A5DB99052315A" modified="2016-02-17" version="1">MSPPDDSKPRSKLTTAFGAPVVDNQNSMTAGPRGPLLMQDLWLIEKLANLNREIIPERRMHAKGSGAFGTFTVTGDIRRYTRAKIFDGVGKQTPMFARFTTVAGERGAADAERDIRGFALKFYTEEGNWDLVGNNTPVFFVRDPRKFPDLNKAVKRDPRSNLRSARNNWDFWTSLPEALHQVTIVMSDRGIPASYRHMHGFGSHTYSFINADNERYWVKFHLKTQQGIKNLTDAEAGELIGRDRESHQRDLFEAIDRGDFPKWKVYIQVMPELDADKVPYHPFDLTKVWPKKDYPLIEVGEMELNRNPDNFYADVEQSAFAPNNLVPGISYSPDKMLQARLFAYSDAQRYRLGVNHHQIPVNAARCPVHSNHRDGAMRVDGNYGGELHYEPNSYGQWQEQPEYREPPLRINGDADFWNFREDDADYYSQPGDLFRLMTPAQQQALFDNTARAMGDAPEFIKRRHIGNCAKADPAYGAGVAKALGLGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJD2</accession>
    <name>A0A0S2DJD2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GumN protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">TraB/GumN family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_15725</name>
        <name evidence="3" type="ORF">GLE_3163</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948090.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3163"/>
    <dbReference type="EnsemblBacteria" id="ALN58509">
        <property type="protein sequence ID" value="ALN58509"/>
        <property type="gene ID" value="GLE_3163"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3163"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3119"/>
    <dbReference type="OMA" id="QTMISWW"/>
    <dbReference type="OrthoDB" id="1991552at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002816">
        <property type="entry name" value="TraB/PrgY/GumN_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01963">
        <property type="entry name" value="TraB_PrgY_gumN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726730" evidence="2">
        <location>
            <begin position="19"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="353" mass="38722" checksum="723279820347F9C2" modified="2016-02-17" version="1">MRLLKLFVLPLCAAVALSAPLTSATATGAVAQAAQAAAKPPPVPLLWRVSDADNAVFLLGSFHLLRADDYPLSDDIQRAFAGSEKLVFEVAPDEMFDPSVGQRFLERARYQDGRTLSQTLPADLREKLNRVLAKNGRSLSQVDSLEPWFVNLSLVLGVSQSLGFSSQLGLDQYLMRQAAEAGKGASGLESMDHQLDVMDASPADEQIKALREFLDRPTEVPDMLEEMHTAWREADLAKLDEKARVEMQQKTPQTYRIVNVERNEAWVPQIQKLLDEQKKGDTLVVVGSLHLLGNDGLVERLRAKGYKIERICSACATGTADLAPMPPAALPPAPPVKLTPDDARESKKAEPRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJD3</accession>
    <name>A0A0S2DJD3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948267.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3401"/>
    <dbReference type="EnsemblBacteria" id="ALN58747">
        <property type="protein sequence ID" value="ALN58747"/>
        <property type="gene ID" value="GLE_3401"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3401"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3350"/>
    <dbReference type="OMA" id="VESEQAW"/>
    <dbReference type="OrthoDB" id="637794at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014917">
        <property type="entry name" value="DUF1800"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08811">
        <property type="entry name" value="DUF1800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="518" mass="55941" checksum="264B1EDFA2F9D3DC" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJF6</accession>
    <name>A0A0S2DJF6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase, families S8 and S53/bacterial pre-peptidase C-terminal domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLE_3294</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3294"/>
    <dbReference type="EnsemblBacteria" id="ALN58640">
        <property type="protein sequence ID" value="ALN58640"/>
        <property type="gene ID" value="GLE_3294"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3294"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3245"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07496">
        <property type="entry name" value="Peptidases_S8_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007280">
        <property type="entry name" value="Peptidase_C_arc/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034176">
        <property type="entry name" value="Peptidases_S8_13"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04151">
        <property type="entry name" value="PPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase_S8" evidence="7">
        <location>
            <begin position="438"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="domain" description="PPC" evidence="8">
        <location>
            <begin position="789"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="175"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="23"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="240"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN58640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="956" mass="99749" checksum="11E6D6DBB9473E1C" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJT5</accession>
    <name>A0A0S2DJT5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF502 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_17000</name>
        <name evidence="2" type="ORF">GLE_3451</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948303.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3451"/>
    <dbReference type="EnsemblBacteria" id="ALN58796">
        <property type="protein sequence ID" value="ALN58796"/>
        <property type="gene ID" value="GLE_3451"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3451"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3399"/>
    <dbReference type="OMA" id="DWSVDQA"/>
    <dbReference type="OrthoDB" id="1305123at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007462">
        <property type="entry name" value="COV1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31876">
        <property type="entry name" value="PTHR31876"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04367">
        <property type="entry name" value="DUF502"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="229" mass="24801" checksum="62BC757BE2A14ED8" modified="2016-02-17" version="1">MRPPNLQRLFLSGLLTLLPIWLTWVVVKFVFVLLSDISKPLVEPLLRDVALAHPQALGWLGSEWVQTALALIATVAVILLTGALARRVVGQTLLRWFESLIRRIPLASTIYGSARQLLDILQTKPDGTQRVVLVDFPHTEMKSIGFVTKVMREEGSGRELAAVYVPTTPNPTSGYLEIVPVEKITPTDWSVDQAMSFIISGGAVSPATIPFSVPSAAAATAAAPDKDAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJV2</accession>
    <name>A0A0S2DJV2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3343</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948226.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3343"/>
    <dbReference type="EnsemblBacteria" id="ALN58689">
        <property type="protein sequence ID" value="ALN58689"/>
        <property type="gene ID" value="GLE_3343"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3343"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3293"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="320" mass="35030" checksum="A63E5479E1CB05A3" modified="2016-02-17" version="1">MRRFRPPRSLRPAAASDSPARWLPMAILAAACASVCALAYPRSPAAMPQRWAPAGIASDQYESSPTFSPDGRELYFMRSDRDFAQWRILHSRCTDAGWSPPAPPAFAAARPGLDADPFVSADGKRVYFVSARHDPKGEDLDIYYVERETGDCKTDDCWSAPVRLPAPVNSPASELLPRALADGRLLFGSARAGGLGQGDLYLAAPRPGGGWRVRNLGAPVSSAANEYEAEISRDGRELIAVTDRGDRSHLYRYRLENGRWRARGRIAARADAFQVGPLLSPRGDRLLFAQADGERSGEFFLIDLKPDPDPRWPPHCAGAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJV3</accession>
    <name>A0A0S2DJV3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_17120</name>
        <name evidence="2" type="ORF">GLE_3475</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057950186.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3475"/>
    <dbReference type="EnsemblBacteria" id="ALN58820">
        <property type="protein sequence ID" value="ALN58820"/>
        <property type="gene ID" value="GLE_3475"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3475"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3422"/>
    <dbReference type="OMA" id="VNLWIGV"/>
    <dbReference type="OrthoDB" id="2076129at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="90" mass="9302" checksum="EA8C132318A14680" modified="2016-02-17" version="1">MHTVLVILGGFVLLAVCLLAGRGFGGAGAAPLILAIKAFLPLWLLGAGINLYIGVARAGYTVAEELPIFLGVYAVPAAVAALLWWRLAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK05</accession>
    <name>A0A0S2DK05_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">bpX6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3489</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948327.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3489"/>
    <dbReference type="EnsemblBacteria" id="ALN58834">
        <property type="protein sequence ID" value="ALN58834"/>
        <property type="gene ID" value="GLE_3489"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3489"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3434"/>
    <dbReference type="OMA" id="VVRQWFL"/>
    <dbReference type="OrthoDB" id="163528at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045547">
        <property type="entry name" value="bpX6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19922">
        <property type="entry name" value="bpX6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="bpX6" evidence="1">
        <location>
            <begin position="9"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="939" mass="100711" checksum="137780128C6E863C" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK10</accession>
    <name>A0A0S2DK10_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">dTDP-glucose 4,6-dehydratase</fullName>
            <ecNumber evidence="4 5">4.2.1.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rfbB</name>
        <name evidence="8" type="ORF">FE772_17925</name>
        <name evidence="7" type="ORF">GLE_3643</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O</text>
            <dbReference type="Rhea" id="RHEA:17221"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57477"/>
            <dbReference type="ChEBI" id="CHEBI:57649"/>
            <dbReference type="EC" id="4.2.1.46"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 5">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.46" evidence="4 5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948439.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3643"/>
    <dbReference type="EnsemblBacteria" id="ALN58987">
        <property type="protein sequence ID" value="ALN58987"/>
        <property type="gene ID" value="GLE_3643"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3643"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3587"/>
    <dbReference type="OMA" id="EWCQHVQ"/>
    <dbReference type="OrthoDB" id="707977at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008460">
        <property type="term" value="F:dTDP-glucose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009225">
        <property type="term" value="P:nucleotide-sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05246">
        <property type="entry name" value="dTDP_GD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005888">
        <property type="entry name" value="dTDP_Gluc_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01181">
        <property type="entry name" value="dTDP_gluc_dehyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="6">
        <location>
            <begin position="5"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW27229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="350" mass="38097" checksum="4CCF72825BFAAA4D" modified="2016-02-17" version="1">MPTWLVTGGAGFIGGNFVLDAVRRGVKVVNLDLLTYAGNRDTLAPLDGEAGHAFVQGDIGDAGLVGRLLAEHRPDAIVNFAAESHVDRSIDGPAAFVHTNVVGTLSLLEQARDYWKSLDAAGRDGFRFLHVSTDEVYGSLGENGKFSETTPYAPNSPYSASKAASDHLVRAFHHTYGLPTLTTNCSNNYGPYQFPEKLIPLVIAKALAGEALPVYGDGMNVRDWLYVGDHCAAIARVLEAGRVGETYNVGGDAERPNLTVVKTICALLDARRPLADGRARESLIAFVADRPGHDRRYAIDASKLKNELGWAPTVTFEQGIERTVEWYLSNQEWVRRVLDGSYRLERIGQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKD8</accession>
    <name>A0A0S2DKD8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-acetylmuramoyl-L-alanine amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_18390</name>
        <name evidence="3" type="ORF">GLE_3734</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948509.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3734"/>
    <dbReference type="EnsemblBacteria" id="ALN59078">
        <property type="protein sequence ID" value="ALN59078"/>
        <property type="gene ID" value="GLE_3734"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3734"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3679"/>
    <dbReference type="OrthoDB" id="1584918at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06583">
        <property type="entry name" value="PGRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036505">
        <property type="entry name" value="Amidase/PGRP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002502">
        <property type="entry name" value="Amidase_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01510">
        <property type="entry name" value="Amidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00644">
        <property type="entry name" value="Ami_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55846">
        <property type="entry name" value="SSF55846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetylmuramoyl-L-alanine amidase" evidence="2">
        <location>
            <begin position="52"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="206" mass="21742" checksum="13CD49BB6F3DF20E" modified="2016-02-17" version="1">MTNLTPNAGPHDAAFDAPHVCAGCDNAEAAAHAAGAGSGPGKPTVNRWEPTSHHSSRNGQDIDHIVVHYTTSRNIEGTISHFKHGSPQTSAHYLIGRDGALVQMVGDGERAWHAGNALMNARSIGIEHVAAVGDRIAEQQARTSAALIGWLMREYEIPKSQVIPHICVPRNTDCCGDLFAGFGGGVKAGAEAQRKALHAWMSSMGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKE2</accession>
    <name>A0A0S2DKE2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">rplQ</name>
        <name evidence="7" type="ORF">BV903_22910</name>
        <name evidence="9" type="ORF">D9T17_09555</name>
        <name evidence="8" type="ORF">FE772_18525</name>
        <name evidence="6" type="ORF">GLE_3765</name>
    </gene>
    <organism evidence="6 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 10">C3</strain>
        </source>
    </reference>
    <reference evidence="7 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">OH11</strain>
        </source>
    </reference>
    <reference evidence="8 13" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 13">YC36</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Contacts protein L32.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the bacterial ribosomal protein bL17 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000077">
        <property type="protein sequence ID" value="OPD61592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000023">
        <property type="protein sequence ID" value="ROU07206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948532.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3765"/>
    <dbReference type="EnsemblBacteria" id="ALN59109">
        <property type="protein sequence ID" value="ALN59109"/>
        <property type="gene ID" value="GLE_3765"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61592">
        <property type="protein sequence ID" value="OPD61592"/>
        <property type="gene ID" value="BV903_22910"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3765"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3709"/>
    <dbReference type="OMA" id="YAVTELF"/>
    <dbReference type="OrthoDB" id="1838961at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01368">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000456">
        <property type="entry name" value="Ribosomal_L17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036373">
        <property type="entry name" value="Ribosomal_L17_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413">
        <property type="entry name" value="PTHR14413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01196">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64263">
        <property type="entry name" value="SSF64263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00059">
        <property type="entry name" value="L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01167">
        <property type="entry name" value="RIBOSOMAL_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD61592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW27337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROU07206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="124" mass="13780" checksum="5719BF3E28C1EF2A" modified="2016-02-17" version="1">MRHQKAGRKFSRTSAHRDAMFTNMAASLIKHGLIRTTLPKAKELRRVAEPLITLAKVDGVANRRLAFSRLRDKEAVGTLFTTLGPRYATRPGGYLRILKCGFRAGDNAPMAYVELVDRPEAAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKF1</accession>
    <name>A0A0S2DKF1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase</fullName>
            <shortName evidence="6">UDP-N-acetylglucosamine acyltransferase</shortName>
            <ecNumber evidence="6">2.3.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">lpxA</name>
        <name evidence="9" type="ORF">BV903_17765</name>
        <name evidence="10" type="ORF">FE772_16690</name>
        <name evidence="8" type="ORF">GLE_3382</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a (3R)-hydroxyacyl-[ACP] + UDP-N-acetyl-alpha-D-glucosamine = a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:67812"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="ChEBI" id="CHEBI:173225"/>
            <dbReference type="EC" id="2.3.1.129"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 1/6.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the transferase hexapeptide repeat family. LpxA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.129" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000048">
        <property type="protein sequence ID" value="OPD62522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948255.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000048.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3382"/>
    <dbReference type="EnsemblBacteria" id="ALN58728">
        <property type="protein sequence ID" value="ALN58728"/>
        <property type="gene ID" value="GLE_3382"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62522">
        <property type="protein sequence ID" value="OPD62522"/>
        <property type="gene ID" value="BV903_17765"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3382"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3332"/>
    <dbReference type="OMA" id="ECVTINR"/>
    <dbReference type="OrthoDB" id="971098at2"/>
    <dbReference type="UniPathway" id="UPA00359">
        <property type="reaction ID" value="UER00477"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008780">
        <property type="term" value="F:acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03351">
        <property type="entry name" value="LbH_UDP-GlcNAc_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00387">
        <property type="entry name" value="LpxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029098">
        <property type="entry name" value="Acetyltransf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037157">
        <property type="entry name" value="Acetyltransf_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010137">
        <property type="entry name" value="Lipid_A_LpxA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43480">
        <property type="entry name" value="PTHR43480"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13720">
        <property type="entry name" value="Acetyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000456">
        <property type="entry name" value="UDP-GlcNAc_acltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01852">
        <property type="entry name" value="lipid_A_lpxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Acetyltransf_11" evidence="7">
        <location>
            <begin position="177"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD62522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="260" mass="27380" checksum="9121C5AE5407AF90" modified="2016-02-17" version="1">MSAAIHPTAFVDPAAKLGDGVVVGAFCYIGADVEVGAGTAFGPHCVVQGPTRIGRDNRFHAQCAIGGDPQDKKFAGERTELVIGDGNSFREFVTVNRGTGSGGGVTRIGDRNWLLAYTHIAHDCQVGNDCVFSNNSTLAGHVVVEDHVIMSGFAGIHQFCRVGAHAFIGMGALVNGDVAPFLMVAQDGYGRPRGINAEGLKRRGFGPERIAAIKRAYRAVFMSGASLEDARAKLEALAADSADVRALLDFIGNGERPLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKR7</accession>
    <name>A0A0S2DKR7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6 8">50S ribosomal protein L3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 10" type="primary">rplC</name>
        <name evidence="12" type="ORF">BV903_23035</name>
        <name evidence="14" type="ORF">D9T17_09430</name>
        <name evidence="13" type="ORF">FE772_18650</name>
        <name evidence="10" type="ORF">GLE_3790</name>
        <name evidence="11" type="ORF">LEN_1353</name>
        <name evidence="15" type="ORF">SAMN05421681_1103</name>
    </gene>
    <organism evidence="10 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 16">C3</strain>
        </source>
    </reference>
    <reference evidence="19" key="2">
        <citation type="journal article" date="2016" name="DNA Res." volume="0" first="0" last="0">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer, Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">M497-1</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="3">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">ATCC 29487</strain>
        </source>
    </reference>
    <reference evidence="11 19" key="4">
        <citation type="journal article" date="2017" name="DNA Res." volume="24" first="169" last="177">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
            <dbReference type="PubMed" id="28065880"/>
            <dbReference type="DOI" id=".1093/dnares/dsw055"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 19">M497-1</strain>
        </source>
    </reference>
    <reference evidence="12 18" key="5">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 18">B25</strain>
        </source>
    </reference>
    <reference evidence="14 20" key="6">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 20">OH11</strain>
        </source>
    </reference>
    <reference evidence="13 21" key="7">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 21">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.</text>
    </comment>
    <comment type="PTM">
        <text evidence="6">Methylated by PrmB.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP014940">
        <property type="protein sequence ID" value="BAV96840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000077">
        <property type="protein sequence ID" value="OPD61617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000023">
        <property type="protein sequence ID" value="ROU07183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNOG01000010">
        <property type="protein sequence ID" value="SDY02948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948555.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3790"/>
    <dbReference type="EnsemblBacteria" id="ALN59134">
        <property type="protein sequence ID" value="ALN59134"/>
        <property type="gene ID" value="GLE_3790"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAV96840">
        <property type="protein sequence ID" value="BAV96840"/>
        <property type="gene ID" value="LEN_1353"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61617">
        <property type="protein sequence ID" value="OPD61617"/>
        <property type="gene ID" value="BV903_23035"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY02948">
        <property type="protein sequence ID" value="SDY02948"/>
        <property type="gene ID" value="SAMN05421681_1103"/>
    </dbReference>
    <dbReference type="KEGG" id="lem:LEN_1353"/>
    <dbReference type="KEGG" id="lez:GLE_3790"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3734"/>
    <dbReference type="OMA" id="KRMAGRY"/>
    <dbReference type="OrthoDB" id="1270636at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000183696">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000218824">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01325_B">
        <property type="entry name" value="Ribosomal_L3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_L3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019927">
        <property type="entry name" value="Ribosomal_L3_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_L3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229">
        <property type="entry name" value="PTHR11229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03625">
        <property type="entry name" value="L3_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0488">Methylation</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 8" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="142"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="modified residue" description="N5-methylglutamine" evidence="6">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAV96840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OPD61617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW27361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROU07183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="SDY02948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000183696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000218824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="217" mass="22990" checksum="EACE50DB40BDD4BD" modified="2016-02-17" version="1">MTAKKYSLGIVGRKAGMSRFFTEDGKSVPVTLIEATPNRITQIKTEDTDGYSAVQVTVGVRRAALVNKPEAGHLAKAKVEAGRGLWELRVEADQIGAFEVGGEIKADIFSAGQLVDVQGVTKGKGFQGTIKRWNFRMGDATHGNSLSHRSPGSIGQRQTPGRVFPGKKMSGHMGAVQQSTQRLEVVKVDAERGLIAIKGAVPGAPGGDVIVRPSSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKY9</accession>
    <name>A0A0S2DKY9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nitroreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_3871</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="2">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the nitroreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3871"/>
    <dbReference type="EnsemblBacteria" id="ALN59214">
        <property type="protein sequence ID" value="ALN59214"/>
        <property type="gene ID" value="GLE_3871"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3871"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3810"/>
    <dbReference type="OMA" id="IPEWEQV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02135">
        <property type="entry name" value="YdjA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026021">
        <property type="entry name" value="YdjA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000232">
        <property type="entry name" value="YdjA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="105"/>
            <end position="107"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000232-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="158" mass="17315" checksum="71FF6621A1798235" modified="2016-02-17" version="1">MLAAAVRVPDHGKRVPFRFLTLQGDARHVLGERVAARGIERFPDAGPAAVEKDRGRFSYAPLIVAVIAQLGPDEKIPELERTLTAGCVCFALLQAAQALGYGAVWLTGWPAYDEQVERWLGVQAHERIVGFIHIGTAKLEAPERERPDPLALTQAWSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL33</accession>
    <name>A0A0S2DL33_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_19570</name>
        <name evidence="2" type="ORF">GLE_3992</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948697.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59334">
        <property type="protein sequence ID" value="ALN59334"/>
        <property type="gene ID" value="GLE_3992"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3992"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3929"/>
    <dbReference type="OMA" id="LENWICD"/>
    <dbReference type="OrthoDB" id="1831282at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="36"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="169" mass="18507" checksum="5D59D380898A2994" modified="2016-02-17" version="1">MTPLTELEGAVLSEIHHRRQQNAFQVRRAFQVSPSIEWSGSAGAVYPAVARLQRRGLIAVGEAADKRATRPLSLTAEGEAALLAWASDGERAASVGLDPFRLRSGIWMGLPPEQRAPVLGEIAAQIEANLRFLDAYVQTVDGIEAVRLRMSMQLQRARLEWIAQALAQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL71</accession>
    <name>A0A0S2DL71_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_19455</name>
        <name evidence="1" type="ORF">GLE_3966</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948681.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59308">
        <property type="protein sequence ID" value="ALN59308"/>
        <property type="gene ID" value="GLE_3966"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3966"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3903"/>
    <dbReference type="OMA" id="NEDHYEL"/>
    <dbReference type="OrthoDB" id="1900440at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="164" mass="18730" checksum="BD78B60AB1A16012" modified="2016-02-17" version="1">MTSPSFRYLRNDEELGWSGFDAYFDYLAGIRERLGEALYAFAADSDRYGLHARGSLHDAWLQRLALAPADACAQRPRMGLELDLLGPWHDRVLCLRYDEVSAYSFVQPPRDGDAAQDLLCHELRLDPTGECLEHFLQFDDGLCILVACRSMRFEEKMLEPPAQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLE7</accession>
    <name>A0A0S2DLE7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome-binding ATPase YchF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 8" type="primary">ychF</name>
        <name evidence="9" type="ORF">FE772_18745</name>
        <name evidence="8" type="ORF">GLE_3806</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948568.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3806"/>
    <dbReference type="EnsemblBacteria" id="ALN59149">
        <property type="protein sequence ID" value="ALN59149"/>
        <property type="gene ID" value="GLE_3806"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3806"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3749"/>
    <dbReference type="OMA" id="VLRCFDN"/>
    <dbReference type="OrthoDB" id="603226at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04867">
        <property type="entry name" value="TGS_YchF_OLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01900">
        <property type="entry name" value="YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00944">
        <property type="entry name" value="YchF_OLA1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004396">
        <property type="entry name" value="ATPase_YchF/OLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023192">
        <property type="entry name" value="TGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013029">
        <property type="entry name" value="YchF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041706">
        <property type="entry name" value="YchF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06071">
        <property type="entry name" value="YchF-GTPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006641">
        <property type="entry name" value="CHP00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00092">
        <property type="entry name" value="TIGR00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="6">
        <location>
            <begin position="3"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="7">
        <location>
            <begin position="278"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="130"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="12"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW27376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="363" mass="39122" checksum="328C42BBF7E25C8B" modified="2016-02-17" version="1">MGIKCGIVGLPNVGKSTLFNALTKAGIAAANFPFCTIEPNVGAVPVPDPRLNALAEIVKPQKLIPTAVEFVDIAGLVAGAASGQGLGNKFLAHIREVDAITHVVRCFEHPDVIHVNNKVDPIADIETIDTELALADLESVEKALQRAERSAKTGDKEAIARKDILGRVRVGLDAGKPARALDLSEDDKAALRDLFLLTLKPVMYVANVLEDGFENNPHLDAVRARAVTEGAQVVPVSAAIEEELSQLDDADRDAFLADLGLEEPGLNRLIRAGYALLGLQTYFTAGVKEVRAWTVRAGSTAPQAAAVIHTDFEKGFIRAETIAYDDFIKYKGESGARDAGRLRLEGKEYRVQEGDVLHFRFNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLK4</accession>
    <name>A0A0S2DLK4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4184</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59526">
        <property type="protein sequence ID" value="ALN59526"/>
        <property type="gene ID" value="GLE_4184"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4184"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4126"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="71" mass="7741" checksum="1C48F136A33725E4" modified="2016-02-17" version="1">MINDERAFSILTSAGAARRAPGVIGFRDRLLPRLRRLAGQPVKPPASQPGALEAFVLRQRDGIDLRADCSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLP2</accession>
    <name>A0A0S2DLP2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4027</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59369">
        <property type="protein sequence ID" value="ALN59369"/>
        <property type="gene ID" value="GLE_4027"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4027"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3966"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025240">
        <property type="entry name" value="DUF4189"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13827">
        <property type="entry name" value="DUF4189"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595346" evidence="1">
        <location>
            <begin position="24"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4189" evidence="2">
        <location>
            <begin position="83"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4189" evidence="2">
        <location>
            <begin position="212"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="408" mass="42610" checksum="71E8FD945D2C0465" modified="2016-02-17" version="1">MNSMRKILLPALLFLGWSVQASAQCSVSGGQQQQQCMQNFVQNVVVPYQQAMQATAQNQPLPPPDSPMELMQAKAGAQARKGWGAVAASPGLAQVGLAGDLGNQRKAESAALKQCADQGGQGCTLMASANNACIALAFNADTQFASAVGQDEIAASRGALSGCNAKSPDKICNLRGEPLCSGVAGGLLQTGGMSTQQRTHLFEIAGDDRQYFGALAGNGKIVYSAANALSQADAEKSAKERCTGPACKLIAAHSNSCLVAAWPKKGGAPFVAESPYPEAARVDALTQCAAANGAGCLVSSPNCSGRAYFDYDYARIHAGAKADSSRSRQAGAALLEAWVGRTEAEFRAHWGSPSATTDIMQGESRLTYEKGYRSKSGVEHSCKVAVFTRAYKVFSYLTEGDVCADVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLS6</accession>
    <name>A0A0S2DLS6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phospho-N-acetylmuramoyl-pentapeptide-transferase</fullName>
            <ecNumber evidence="9">2.7.8.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">UDP-MurNAc-pentapeptide phosphotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 10" type="primary">mraY</name>
        <name evidence="11" type="ORF">BV903_07600</name>
        <name evidence="12" type="ORF">FE772_20260</name>
        <name evidence="10" type="ORF">GLE_4133</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">C3</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine = di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP</text>
            <dbReference type="Rhea" id="RHEA:28386"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:61387"/>
            <dbReference type="EC" id="2.7.8.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="9">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyltransferase 4 family. MraY subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.13" evidence="9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000015">
        <property type="protein sequence ID" value="OPD64520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948812.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4133"/>
    <dbReference type="EnsemblBacteria" id="ALN59475">
        <property type="protein sequence ID" value="ALN59475"/>
        <property type="gene ID" value="GLE_4133"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64520">
        <property type="protein sequence ID" value="OPD64520"/>
        <property type="gene ID" value="BV903_07600"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4133"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4075"/>
    <dbReference type="OMA" id="LMSPLHH"/>
    <dbReference type="OrthoDB" id="1151822at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008963">
        <property type="term" value="F:phospho-N-acetylmuramoyl-pentapeptide-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051992">
        <property type="term" value="F:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06852">
        <property type="entry name" value="GT_MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00038">
        <property type="entry name" value="MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003524">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018480">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22926">
        <property type="entry name" value="PTHR22926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10555">
        <property type="entry name" value="MraY_sig1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00445">
        <property type="entry name" value="mraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01347">
        <property type="entry name" value="MRAY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01348">
        <property type="entry name" value="MRAY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0133">Cell shape</keyword>
    <keyword evidence="9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="66"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="240"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OPD64520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW27624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="361" mass="39472" checksum="300E3925E05BF2B6" modified="2016-02-17" version="1">MLLELTRWLEQLQSLFNIFGYLTFRGILSALTSLALSLWWGPAVIRKLGQLKGGQPIRKDGPQSHFSKAGTPTMGGALILFTVMASVLLWGDLRNKYVWIVLLVMLAFGAIGWYDDWIKIVKRDPNGLKSRWKYLLQSIFGLAAGLYLWLYADVPAATTFYVPLFKSVALPLAGVSFVALAYLWIVGFSNAVNLTDGLDGLAIMPTVLVACALGIFAYASGHAEFSKYLQIPAVPGAGELVIICAAIAGAGLGFLWFNTYPAMVFMGDIGALALGAVLGTIAIIVRQELVLVIMGGIFVIETLSVMIQVASFKLTGKRVFRMAPIHHHFELKGWPEPRVIVRFWIISVVLVLVGLATLKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLX7</accession>
    <name>A0A0S2DLX7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3817</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3817"/>
    <dbReference type="EnsemblBacteria" id="ALN59160">
        <property type="protein sequence ID" value="ALN59160"/>
        <property type="gene ID" value="GLE_3817"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3817"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3759"/>
    <dbReference type="OMA" id="PSMAEAH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029489">
        <property type="entry name" value="OGT/SEC/SPY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13844">
        <property type="entry name" value="Glyco_transf_41"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="53"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_transf_41" evidence="2">
        <location>
            <begin position="135"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_transf_41" evidence="2">
        <location>
            <begin position="365"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="575" mass="61644" checksum="F3EB2D11FB84A82B" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLY9</accession>
    <name>A0A0S2DLY9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase</fullName>
            <shortName evidence="10">NN:DBI PRT</shortName>
            <ecNumber evidence="4 10">2.4.2.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">N(1)-alpha-phosphoribosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 11" type="primary">cobT</name>
        <name evidence="11" type="ORF">GLE_4083</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>5,6-dimethylbenzimidazole + nicotinate beta-D-ribonucleotide = alpha-ribazole 5'-phosphate + H(+) + nicotinate</text>
            <dbReference type="Rhea" id="RHEA:11196"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15890"/>
            <dbReference type="ChEBI" id="CHEBI:32544"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:57918"/>
            <dbReference type="EC" id="2.4.2.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Nucleoside biosynthesis; alpha-ribazole biosynthesis; alpha-ribazole from 5,6-dimethylbenzimidazole: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the CobT family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.21" evidence="4 10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4083"/>
    <dbReference type="EnsemblBacteria" id="ALN59425">
        <property type="protein sequence ID" value="ALN59425"/>
        <property type="gene ID" value="GLE_4083"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4083"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4025"/>
    <dbReference type="OMA" id="AWMRKCA"/>
    <dbReference type="UniPathway" id="UPA00061">
        <property type="reaction ID" value="UER00516"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008939">
        <property type="term" value="F:nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02439">
        <property type="entry name" value="DMB-PRT_CobT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1610.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00230">
        <property type="entry name" value="CobT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003200">
        <property type="entry name" value="Nict_dMeBzImd_PRibTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017846">
        <property type="entry name" value="Nict_dMeBzImd_PRibTrfase_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023195">
        <property type="entry name" value="Nict_dMeBzImd_PRibTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036087">
        <property type="entry name" value="Nict_dMeBzImd_PRibTrfase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02277">
        <property type="entry name" value="DBI_PRT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52733">
        <property type="entry name" value="SSF52733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03160">
        <property type="entry name" value="cobT_DBIPRT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="7 10 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10 11" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN59425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="362" mass="36695" checksum="F75BF7773CCD13AA" modified="2016-02-17" version="1">MNDETSWWLRECLRADEDSAAQARARQDQLTKPPGSLGRLEELAVRLAGLQRSQRPSLQRVWISVFAADHGVAAEGVSAFPQAVTGEMLRNFAGGGAAIAVLARSLGASLDVVNLGTVNDPGPIKGVHRAIVAASTANFCEAAAMTPAQLRAALAAGAASVRAARDAGAQLFVGGEMGIANTTAAAALASALLDCAPARLAGAGTGLDAAGIAHKTAVIERALALHADAGSDWERLRRLGGFEIAALTGAYIACAQVGVAVLVDGFIATVAALAAQRLNPGCGPWLLYAHRSHERGHAALLDALDAQPLLDLGLRLGEASGAAVAVPLLRLACELHAGMATFAQAGVSGANGSHSDPAAARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM14</accession>
    <name>A0A0S2DM14_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4105 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4430</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4430"/>
    <dbReference type="EnsemblBacteria" id="ALN59771">
        <property type="protein sequence ID" value="ALN59771"/>
        <property type="gene ID" value="GLE_4430"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4430"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4367"/>
    <dbReference type="OMA" id="GGFFRQF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025178">
        <property type="entry name" value="DUF4105"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13387">
        <property type="entry name" value="DUF4105"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4105" evidence="2">
        <location>
            <begin position="140"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="359" mass="39812" checksum="A7D80EDD58457CE9" modified="2016-02-17" version="1">MPAEDIPPAPSAGRRWLRIAAMGLAALAILAVAAWGAGLIAFQFPGAALLRNGLIVLWCLLGVAACVALPWRRRGAARRPALIAFAAGFAALLAWWSAIAPSQDRDWADDVARQFDAQVRGDRVVLHNVRNFQWRSESDYTPRWETREYDLSRLSSADLVLSYWMGPDIAHTLVSFGFDDGQRLVFSLEIRKQRGESFSALGGFFRRFEQVLVAADERDIVRTRSNARGEDVYLYRLNVPPRTLRPMFLGFLAKADALRRAPSFYNTLTSNCTTVVFEIARHVVPDLPLDYRLLAAGHFAEYVYDQGGLTPGYSYAQLHERGYVNPRARSIPADAADADAYSRAIRRGVPGIAAAETAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM57</accession>
    <name>A0A0S2DM57_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59632">
        <property type="protein sequence ID" value="ALN59632"/>
        <property type="gene ID" value="GLE_4291"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4291"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4230"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="39" mass="4357" checksum="FAF667EA09DBB67E" modified="2016-02-17" version="1">MRAGARGHAWPREVAPRSALARSRLAPLLQGLRPVRIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMD6</accession>
    <name>A0A0S2DMD6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Integrase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_4295</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the transposition of the insertion element.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transposase IS30 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59636">
        <property type="protein sequence ID" value="ALN59636"/>
        <property type="gene ID" value="GLE_4295"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4295"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4234"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001598">
        <property type="entry name" value="Transposase_IS30_CS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01043">
        <property type="entry name" value="TRANSPOSASE_IS30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="4">
        <location>
            <begin position="94"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="59"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="259" mass="29341" checksum="EB1937CBEE293B2C" modified="2016-02-17" version="1">MSRXXXXXXXTVLVAATDADKLRDLYPDRPWLRVSHETIYTAIYAMPRGELRRQVTRLLRQGRKSGRRTRQGSDARGHLPDLPNIRLRPPAAHERLMPGHWEGDLIVGAHNRSAIGVLVCRRTLYVKLVKLADATAHTVLEAFSSAFEGVPESLKKTLTYDQGKEMASHRQLSERTGLAIYFADPHSPWQRGTCENTNGLLRQYFPKGTDLSVHSAQRLKEVAWEMNNRPRRSLGRRSPVEVLYEELKNPRAQGDALGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMN0</accession>
    <name>A0A0S2DMN0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB-dependent receptor</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">TonB-dependent receptor domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BV903_11985</name>
        <name evidence="9" type="ORF">GLE_4423</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">B25</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000028">
        <property type="protein sequence ID" value="OPD63763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949042.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000028.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4423"/>
    <dbReference type="EnsemblBacteria" id="ALN59764">
        <property type="protein sequence ID" value="ALN59764"/>
        <property type="gene ID" value="GLE_4423"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63763">
        <property type="protein sequence ID" value="OPD63763"/>
        <property type="gene ID" value="BV903_11985"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4423"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4361"/>
    <dbReference type="OMA" id="WQVGAFY"/>
    <dbReference type="OrthoDB" id="514956at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595850" evidence="6">
        <location>
            <begin position="49"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="83"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="7">
        <location>
            <begin position="330"/>
            <end position="792"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN59764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD63763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="794" mass="86310" checksum="40A75ED7CC962E24" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMW5</accession>
    <name>A0A0S2DMW5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent protease subunit HslV</fullName>
            <ecNumber evidence="7">3.4.25.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 8" type="primary">hslV</name>
        <name evidence="9" type="ORF">BV903_03590</name>
        <name evidence="10" type="ORF">FE772_22125</name>
        <name evidence="8" type="ORF">GLE_4531</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP-dependent cleavage of peptide bonds with broad specificity.</text>
            <dbReference type="EC" id="3.4.25.2"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="7">Allosterically activated by HslU binding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase T1B family. HslV subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.25.2" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000006">
        <property type="protein sequence ID" value="OPD65380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949125.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4531"/>
    <dbReference type="EnsemblBacteria" id="ALN59872">
        <property type="protein sequence ID" value="ALN59872"/>
        <property type="gene ID" value="GLE_4531"/>
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    <dbReference type="EnsemblBacteria" id="OPD65380">
        <property type="protein sequence ID" value="OPD65380"/>
        <property type="gene ID" value="BV903_03590"/>
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    <dbReference type="KEGG" id="lez:GLE_4531"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4467"/>
    <dbReference type="OMA" id="IMKGNAR"/>
    <dbReference type="OrthoDB" id="1129370at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009376">
        <property type="term" value="C:HslUV protease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005839">
        <property type="term" value="C:proteasome core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01913">
        <property type="entry name" value="protease_HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00248">
        <property type="entry name" value="HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022281">
        <property type="entry name" value="ATP-dep_Prtase_HsIV_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="PTHR32194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039093">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03692">
        <property type="entry name" value="ATP_dep_HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0915">Sodium</keyword>
    <keyword evidence="4 7" id="KW-0888">Threonine protease</keyword>
    <feature type="active site" evidence="7">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </ligand>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD65380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="183" mass="19413" checksum="A07AD928DFFC0A71" modified="2016-02-17" version="1">MDPSQNPNVFHATTIVSVRRDGRVAIAGDGQVTLGHTVMKSNARKVRRLGRDGQVLAGFAGAAADAFTLFELFEAKLEKHGQLTRAAVELAKDWRTERRLGKLEALLAVADKETSLVISGTGDVIEPEDGIVAIGSGGMYALSAARALMAHSSLDARGIATEAINIAGDVCIYTNRNVVVEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMY7</accession>
    <name>A0A0S2DMY7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BV903_03645</name>
        <name evidence="5" type="ORF">GLE_4543</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">B25</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="ALN59884"/>
        <property type="gene ID" value="GLE_4543"/>
    </dbReference>
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        <property type="gene ID" value="BV903_03645"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD65390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="164" mass="17345" checksum="2CDFD0B094319C1C" modified="2016-02-17" version="1">MVAAVDKFLAAKSYHASMSMGPGAATETDFVAPDRMRVRLGAVGDQVLIGDTMYVTVQGKTRKQPAPGGGVAGTRSREKVLGNLQTLKVAALGSETLAGTATRKYKVENSQPNKTSSTFWVAADTGYPVQAVNVAEVGGKTYTSTLKYSRYNDPSIRIEAPAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNM4</accession>
    <name>A0A0S2DNM4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4656</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59997">
        <property type="protein sequence ID" value="ALN59997"/>
        <property type="gene ID" value="GLE_4656"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4656"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4592"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="445" mass="48977" checksum="A1CA2282C53B84C9" modified="2016-02-17" version="1">MARSEQRFQRTAAAIGEANMAGAAADAVARLQTGADAVLQAGLNDRLAAGDARIDRDFDGRWDAMQAKARREAQAQAQAQAQAQAQAAAVREARFFAGSRHAGLSGQDLELSLAASSQRLRDNAARAEEDAEMLANIREFEAREARHEQRYGPREHRPMPKPSLEKQIWDYSPQGRSWNVLGAMGGDVLMSLGMAEVVKNEYGPDYTVHPFTKEWMSPGEVKDTRFLTLVGFVPMARAETAVAGEFKGMLSSLRTFFSSASDDAIRMVPGGNAKGLPFRVVENDSPRIFGQELEYSCGAACARTLLQDSGVDIAERAVREEFRRFNLNGGVMADDLAGAMNKIGDARGVERKFTGGMIEGDRIEELLPQFKAMTEAGDPFFANLNRHWVIVDGFDSGAGVVRIRDPWNNNIPKGEFRFFEHGRTVEMNEAEFINRWKATDGSAVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNR9</accession>
    <name>A0A0S2DNR9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Efflux transporter outer membrane subunit</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_22820</name>
        <name evidence="4" type="ORF">GLE_4688</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949238.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4688"/>
    <dbReference type="EnsemblBacteria" id="ALN60029">
        <property type="protein sequence ID" value="ALN60029"/>
        <property type="gene ID" value="GLE_4688"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4688"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4623"/>
    <dbReference type="OMA" id="NFMVTNL"/>
    <dbReference type="OrthoDB" id="1619477at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5034034607" evidence="2">
        <location>
            <begin position="24"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW28052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="485" mass="52025" checksum="DD2A437E079B7896" modified="2016-02-17" version="1">MSKFSTHALALAIALAATGCVSLAPKLPAQEAGIPAQWPLPPTTQSFVGAQPLTSDPAASQTAAASEGAAVADIGWRDFFEDPNLEQLIGRALDNNRDLRVAVLNVERARAQYRIQRADRLPALNATAQLRRTGGDNQQVVDEYQAGASIANFELDLFGRVRSLSQSALQRYFAEEEARRAAQLSLIAEVANAYLTLAADRELLSVSEATLKNQQSAYDLTQKRRELGAVSGLELSQARTQVEQARADAARYAGQVAQDTNALNLLVGEQVDPALLPSKLTAGVTGLAALPQGLPSEVLLRRPDVLQAEHLLRAQNANIGAARAAFFPSISLTGFLGSASNELSGLFDSNTRSWLVNPVVNIPIFQGGKLRANLASAKADQKIALAQYEKAIQAGFRDVSDALALTKTLAEQRQAQEALVEAAARADQLSTARYKAGRDSYLNQLDAQRTLYGAQQGLVTTRLAEQSNRVALYKVLGGGWNERSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNU5</accession>
    <name>A0A0S2DNU5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase sigma factor RpoH</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">RNA polymerase sigma-32 factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">rpoH</name>
        <name evidence="10" type="ORF">BV903_06580</name>
        <name evidence="11" type="ORF">FE772_23695</name>
        <name evidence="9" type="ORF">GLE_4879</name>
    </gene>
    <organism evidence="9 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">C3</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts with the RNA polymerase core enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the sigma-70 factor family. RpoH subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000012">
        <property type="protein sequence ID" value="OPD64697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949384.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000012.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4879"/>
    <dbReference type="EnsemblBacteria" id="ALN60220">
        <property type="protein sequence ID" value="ALN60220"/>
        <property type="gene ID" value="GLE_4879"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64697">
        <property type="protein sequence ID" value="OPD64697"/>
        <property type="gene ID" value="BV903_06580"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4879"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4810"/>
    <dbReference type="OMA" id="YQRWLAE"/>
    <dbReference type="OrthoDB" id="1565734at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00961">
        <property type="entry name" value="Sigma70_RpoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012759">
        <property type="entry name" value="RNA_pol_sigma_RpoH_proteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000770">
        <property type="entry name" value="RNA_pol_sigma-SigE/K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02392">
        <property type="entry name" value="rpoH_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2 6" id="KW-0346">Stress response</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="1 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="7">
        <location>
            <begin position="85"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_sigma70" evidence="8">
        <location>
            <begin position="260"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="6">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-2" evidence="6">
        <location>
            <begin position="61"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-4" evidence="6">
        <location>
            <begin position="236"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Interaction with polymerase core subunit RpoC" evidence="6">
        <location>
            <begin position="85"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN60220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD64697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW28201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="292" mass="32845" checksum="CFEACA0438A69503" modified="2016-02-17" version="1">MTSIAQSSALVANNLPVPSALGSLDAYIGAVHQIPVLTAEDEQALARRFRDEEDLDAARELVHSHLRFVVHVARGYNGYGLQIGDLIQEGNIGLMKAVKRFDPEQGVRLVSFAVHWIRAEMHEFILKNWRIVKVATTKAQRKLFFNLRKSKKRLGWMNAEEVSQVAKDLNVSEREVLEMESRLSGRDIGFDAPADEDDDHAPPSPAAYLRAAEEDPSQSYEREDEEDNQLALLREGLAGLDARSRDIVKRRWLDADSKVTLQELADEYGVSAERIRQIEANALKKMRGLFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP46</accession>
    <name>A0A0S2DP46_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Taurine catabolism dioxygenase TauD, TfdA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4812</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949332.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4812"/>
    <dbReference type="EnsemblBacteria" id="ALN60153">
        <property type="protein sequence ID" value="ALN60153"/>
        <property type="gene ID" value="GLE_4812"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4812"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4744"/>
    <dbReference type="OMA" id="HIFANNY"/>
    <dbReference type="OrthoDB" id="1742732at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD" evidence="2">
        <location>
            <begin position="27"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="278" mass="31283" checksum="16789089E13EDD93" modified="2016-02-17" version="1">MNYEMSPMQPFGLMLRPAGGAVDVRELPIAELREHVRRHRLLALRGFGSFAGAEDFADYCEGWGEVSLWPFGKVLELVEHEAPEDHIFDNKYVPLHWDGMYRKQVPEFQVFHCVSAPAVAQGGRTTFSDTAGALERAAPDLRSLWSRATGVYRRKMEFYDSKTIAPVVTAHPVRGFPVIRYNEPPAADAAGFVNRPDLEFVGVEPNELGEFHRSLHEALYAPQNLYAHAWQDGDVVVTDNYTLLHGREGFVSGAPRHLRRVHVLGDPPLDNPHLVAYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPE8</accession>
    <name>A0A0S2DPE8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pteridine-dependent deoxygenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Pteridine-dependent deoxygenase like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_24135</name>
        <name evidence="1" type="ORF">GLE_4979</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949459.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4979"/>
    <dbReference type="EnsemblBacteria" id="ALN60320">
        <property type="protein sequence ID" value="ALN60320"/>
        <property type="gene ID" value="GLE_4979"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4979"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4906"/>
    <dbReference type="OMA" id="QVSAYHY"/>
    <dbReference type="OrthoDB" id="1999999at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="338" mass="36947" checksum="93FF0B4A42F6EA27" modified="2016-02-17" version="1">MSAAAATVAGPRLDVDYLDTDPAQALAQDDTLALFGFGQDAPHHDDPRYLRVPLEPVGDRRLERWRGNGPVARGRDGDLAWAEDGALQFGVIEVDEPAPLPGEPANGEIGRAAEYLYRKLLAFTAQRGYPQLLRIWNYLDGITLGHGDEERYRVFCVGRAAGLGEFPIARLPAATAIGRVDGARRLQVYWLASRTAGTPLENPRQVSAYRYPRQYGPQSPSFARAMLPPGPARMPLLLSGTAAVVGHESRHAESVLAQLEETLANFDSLIGAARQHRPDLPPAFGPGSRLKVYVRDLPDLPIVAAELDRRYGDRVPRILVHAAVCRHELLVEIDGVHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPG1</accession>
    <name>A0A0S2DPG1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Proline hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_24375</name>
        <name evidence="3" type="ORF">GLE_5028</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5028"/>
    <dbReference type="EnsemblBacteria" id="ALN60369">
        <property type="protein sequence ID" value="ALN60369"/>
        <property type="gene ID" value="GLE_5028"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5028"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4956"/>
    <dbReference type="OMA" id="MARHRFG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018655">
        <property type="entry name" value="DUF2086"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09859">
        <property type="entry name" value="Oxygenase-NA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="2">
        <location>
            <begin position="137"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="251" mass="28284" checksum="B706633F3E063B1E" modified="2016-02-17" version="1">MRAETDTAADAVRDPRQRLCRRIVGYDWDALTAALDANGWAVLPKLLGARQCAALAEGYDEDARYRSRVIMQRHGFGRGEYRYFRYPLPPLLQTLRESLYPRLAPVATRWNAMLGVDDAYPDTLEAFLARCHAAGQTRPTPLLLRYGAGDYNCLHQDVYGAHVFPLQVAILLSQPGRDFDGGEFVLTEQRPRMQSRAQVVPLQQGDAVIFAVRHRPQRGARGFYRVNLRHGVSALRAGTRHTLGVIFHDAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPM9</accession>
    <name>A0A0S2DPM9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">GLE_5165</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949601.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5165"/>
    <dbReference type="EnsemblBacteria" id="ALN60506">
        <property type="protein sequence ID" value="ALN60506"/>
        <property type="gene ID" value="GLE_5165"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5165"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5087"/>
    <dbReference type="OMA" id="CTADVFQ"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003122">
        <property type="entry name" value="Tar_rcpt_lig-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02203">
        <property type="entry name" value="TarH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 10" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="HAMP" evidence="16">
        <location>
            <begin position="213"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="14">
        <location>
            <begin position="284"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="15">
        <location>
            <begin position="372"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="12">
        <location>
            <begin position="442"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="13">
        <location>
            <begin position="701"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="domain" description="HPt" evidence="17">
        <location>
            <begin position="864"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="408"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="10">
        <location>
            <position position="750"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="9">
        <location>
            <position position="903"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ALN60506.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="955" mass="103025" checksum="23F9FA3683637AAF" modified="2016-02-17" version="1"> </sequence>
</entry>
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    <accession>A0A0S2DPV8</accession>
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        </submittedName>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 7">C3</strain>
        </source>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
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    <dbReference type="STRING" id="69.GLE_5353"/>
    <dbReference type="EnsemblBacteria" id="ALN60694">
        <property type="protein sequence ID" value="ALN60694"/>
        <property type="gene ID" value="GLE_5353"/>
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    <dbReference type="KEGG" id="lez:GLE_5353"/>
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    <dbReference type="OMA" id="IMCAFLV"/>
    <dbReference type="OrthoDB" id="1926714at2"/>
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    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="match status" value="1"/>
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        <location>
            <begin position="2"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
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    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW24294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="248" mass="26815" checksum="CF1E19FCAF63E5DC" modified="2016-02-17" version="1">MIIAHDLHKSFKTKTGTVAAVQGVDFEARDGQITGLLGPNGAGKTTTLRMLYTLMRPDRGEVRVDGVDAAQDPAAVRRALGVLPDARGVYKRLTARENIAYFGELHGLGRAQIEQRTLALAKALDMGDILDRQTEGFSQGQRTKTAIARALVHDPRNVILDEPTNGLDVMTTRAMRGFLRGLREEGRCVIFSSHIMQEVAALCDRIVIIAKGQVVAAGTADELRAQTGEDNLEDAFVKAIGSDEGLHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPY6</accession>
    <name>A0A0S2DPY6_LYSEN</name>
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        <submittedName>
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        </submittedName>
    </protein>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.-.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ALN60528">
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        <property type="gene ID" value="GLE_5187"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5187"/>
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    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        </location>
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    <evidence type="ECO:0000256" key="1">
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    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="159" mass="16473" checksum="1DD734E5CDD1FEE6" modified="2016-02-17" version="1">MSASDPTSPAAPAAQPPAAKPLFRGATTVDDLNRLSRNTAMEPLGIVFTEIGPDYVRGTMPVDPRTHQPYGLLHGGASVLLAETLGSSAGNLCCAAGKVCVGIEINANHVRGVRSGTVVGTARPIHVGASTQVWDIRIEDEAGRLVCVSRLTLAVVPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ11</accession>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    <reference evidence="2 4" key="2">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
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    </dbReference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="ALN60827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="1158" mass="128040" checksum="757074ABE72772AA" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQG3</accession>
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    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="GLE_5511"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5511"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5425"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="38" mass="4313" checksum="F630EA72202C6A05" modified="2016-02-17" version="1">MPGNPTIHHINAWRDFAASLISAFPDWKMRSMSPTVTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQT7</accession>
    <name>A0A0S2DQT7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5523</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5523"/>
    <dbReference type="EnsemblBacteria" id="ALN60864">
        <property type="protein sequence ID" value="ALN60864"/>
        <property type="gene ID" value="GLE_5523"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5523"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="148" mass="15945" checksum="E3318FBC8C2BDFBA" modified="2016-02-17" version="1">MADGSIDAARADAEWAASTDPAQSTLGARTRPARARATAAAFADDGAPGAPTSNSYAQARTANEVLKAQHHKLRIAQLRGELIDRQQAVGQVFALARAERDAWLNWPARISSMLAAELGIDPHAMHIALEREVRQHLSELGDFVARLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQU8</accession>
    <name>A0A0S2DQU8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">2,5-didehydrogluconate reductase DkgB</fullName>
            <ecNumber evidence="6">1.1.1.346</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="5">2,5-diketo-d-gluconic acid reductase B</fullName>
            <ecNumber evidence="5">1.1.1.274</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">dkgB</name>
        <name evidence="6" type="ORF">FE772_00035</name>
        <name evidence="5" type="ORF">GLE_5346</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.346" evidence="6"/>
    <dbReference type="EC" id="1.1.1.274" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949738.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5346"/>
    <dbReference type="EnsemblBacteria" id="ALN60687">
        <property type="protein sequence ID" value="ALN60687"/>
        <property type="gene ID" value="GLE_5346"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5346"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5262"/>
    <dbReference type="OMA" id="WRHPDEP"/>
    <dbReference type="OrthoDB" id="1035565at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050580">
        <property type="term" value="F:2,5-didehydrogluconate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="PTHR43827"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00798">
        <property type="entry name" value="ALDOKETO_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="4">
        <location>
            <begin position="7"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="3">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW24291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="267" mass="29040" checksum="E6BB5F3DCFD14003" modified="2016-02-17" version="1">MSVPAFGLGTFRLQGQTVVDSVRTGLELGYRAIDTAQIYGNEAQVGQALADSGVARGEVYLTTKIWIDNLARERLIPSLRESLAKLRTDYVDLTLIHWPSPNDAVAVDEFMAAVLQAKREGLTRAIGVSNFNIELMQRAIAAVGSDEIATNQVELHPYLQNHKLAQFAREAGIGLTSYMTLAYGKVLNDPVLVDIAGKHRATPAQVALAWAMQSGYAVIPSSTKRENLAGNLLAMSLRLDDEDLRRIAALDRGERLTDPAGLAPAWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQX7</accession>
    <name>A0A0S2DQX7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Outer membrane usher protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLE_5456</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cell outer membrane</location>
            <topology evidence="2 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the fimbrial export usher family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5456"/>
    <dbReference type="EnsemblBacteria" id="ALN60797">
        <property type="protein sequence ID" value="ALN60797"/>
        <property type="gene ID" value="GLE_5456"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5456"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5371"/>
    <dbReference type="OMA" id="QACKTID"/>
    <dbReference type="OrthoDB" id="120032at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015473">
        <property type="term" value="F:fimbrial usher porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009297">
        <property type="term" value="P:pilus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000015">
        <property type="entry name" value="Fimb_usher"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018030">
        <property type="entry name" value="Fimbrial_membr_usher_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042186">
        <property type="entry name" value="FimD_plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025949">
        <property type="entry name" value="PapC-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043142">
        <property type="entry name" value="PapC-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025885">
        <property type="entry name" value="PapC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037224">
        <property type="entry name" value="PapC_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30451">
        <property type="entry name" value="PTHR30451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13953">
        <property type="entry name" value="PapC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13954">
        <property type="entry name" value="PapC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00577">
        <property type="entry name" value="Usher"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141729">
        <property type="entry name" value="SSF141729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01151">
        <property type="entry name" value="FIMBRIAL_USHER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="10" id="KW-1029">Fimbrium biogenesis</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PapC_N" evidence="13">
        <location>
            <begin position="111"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="PapC_C" evidence="12">
        <location>
            <begin position="808"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="39"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="43"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="58"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="91"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN60797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="894" mass="93857" checksum="A2AA9B11345B1302" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2D9Z1</accession>
    <name>A0A0S2D9Z1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0013</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55372">
        <property type="protein sequence ID" value="ALN55372"/>
        <property type="gene ID" value="GLE_0013"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0013"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="44" mass="4765" checksum="490E71840CAB3468" modified="2016-02-17" version="1">MAAIAPSALFYATPWRWYFHTAPVDSVQDARAVQLGSSLPPSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA12</accession>
    <name>A0A0S2DA12_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tail length tape measure protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_01080</name>
        <name evidence="1" type="ORF">GLE_0029</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945740.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0029"/>
    <dbReference type="EnsemblBacteria" id="ALN55388">
        <property type="protein sequence ID" value="ALN55388"/>
        <property type="gene ID" value="GLE_0029"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0029"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.36"/>
    <dbReference type="OrthoDB" id="1197582at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="353" mass="36342" checksum="FB2E2860E1D514E4" modified="2016-02-17" version="1">MEAKIERVFGDQSRQEQSIQTRQQARLLTEIGARRELLDLHGRTAAEVDQLLPKMDALAAKTGSPEAIERVKDLTAQVAALKTQSNELVVTLTNGFETGLGSALEGLATGTLTLRQALTGLVQDMARSLAQLASQQLAALATAKLMSLVGKIAGGDKTPDLAQPDPVQAAAAGAAYATPIAGASVALGVAGGVVLKAAGAMQAAAATLAAANATKGASGFFAAGGFTGIGPKYAPAGIVHRGEFVNRREVVRQPGARSFLERFNRVGMAALDGLRGFAGGGFVLPAPTTRAPVRRSVSERSAASASGSRSSQITNVLYLDPREIVNVIGSQAGRQVILSTIRANAPTVRQDLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA15</accession>
    <name>A0A0S2DA15_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_01070</name>
        <name evidence="1" type="ORF">GLE_0027</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945738.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0027"/>
    <dbReference type="EnsemblBacteria" id="ALN55386">
        <property type="protein sequence ID" value="ALN55386"/>
        <property type="gene ID" value="GLE_0027"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0027"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.34"/>
    <dbReference type="OMA" id="WATESEH"/>
    <dbReference type="OrthoDB" id="1865189at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="198" mass="21506" checksum="F9E5C5407842EF36" modified="2016-02-17" version="1">MSSAWNNFNDAESPSFALIPKGSLVKVRMTIKPGGYNDPANGWMHGWATRGDTGAVYLNAEFVVVEGKYARRKLWTLIGLHSPKGPTWGQMGRSFIKGVLNSAHALHPDDMSAAAQQGRCIESFGDLDGVVFAGKVDWEKDSYGEDKAVIKMPIMPDHPQYRECMSGESPAISRDMPAHIAQATTAATTPSGRPAWAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA74</accession>
    <name>A0A0S2DA74_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">4-hydroxybenzoate octaprenyltransferase</fullName>
            <ecNumber evidence="9">2.5.1.39</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">4-HB polyprenyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 10" type="primary">ubiA</name>
        <name evidence="11" type="ORF">BV903_05565</name>
        <name evidence="12" type="ORF">FE772_01210</name>
        <name evidence="10" type="ORF">GLE_0054</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">C3</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>4-hydroxybenzoate + all-trans-octaprenyl diphosphate = 4-hydroxy-3-all-trans-octaprenylbenzoate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:27782"/>
            <dbReference type="ChEBI" id="CHEBI:1617"/>
            <dbReference type="ChEBI" id="CHEBI:17879"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57711"/>
            <dbReference type="EC" id="2.5.1.39"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="9">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the UbiA prenyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.39" evidence="9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000010">
        <property type="protein sequence ID" value="OPD64958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945761.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0054"/>
    <dbReference type="EnsemblBacteria" id="ALN55413">
        <property type="protein sequence ID" value="ALN55413"/>
        <property type="gene ID" value="GLE_0054"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64958">
        <property type="protein sequence ID" value="OPD64958"/>
        <property type="gene ID" value="BV903_05565"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0054"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.61"/>
    <dbReference type="OMA" id="MVVYPYG"/>
    <dbReference type="OrthoDB" id="1472516at2"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002083">
        <property type="term" value="F:4-hydroxybenzoate decaprenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047293">
        <property type="term" value="F:4-hydroxybenzoate nonaprenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008412">
        <property type="term" value="F:4-hydroxybenzoate octaprenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13959">
        <property type="entry name" value="PT_UbiA_COQ2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01635">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006370">
        <property type="entry name" value="HB_polyprenyltransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039653">
        <property type="entry name" value="Prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030470">
        <property type="entry name" value="UbiA_prenylTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048">
        <property type="entry name" value="PTHR11048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01474">
        <property type="entry name" value="ubiA_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00943">
        <property type="entry name" value="UBIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 9" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="151"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="244"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN55413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OPD64958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW24499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="303" mass="33923" checksum="F5BD69F093351A43" modified="2016-02-17" version="1">MQRAHSHLPAPDWRRRLSLYWKLTRGDRPIGWLLLLWPTWWGLWIAAGGMPSLWVLFVFSAGVWLTRAAGCVINDYADRWLDPHVERTKHRPLATGEVRGREALAVFAALMLAAFALVLTLNRLTVLMSAVGVVLAASYPYLKRYTHLPQVYLGMAFGWGIPMAFAAVRGEVPAVAWLLYAANILWSTAYDTWYAMVDREDDLKMGSKSTAILFGELDLVAIGVLYALMFAALFLVGQRAGLGPWYYAGLAAAAALVAYEFVIARGRERERCFRAFLHNHWVGLTIFAGLALDYLLRNTSTVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAB5</accession>
    <name>A0A0S2DAB5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type I pili usher pathway</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0102</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945797.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0102"/>
    <dbReference type="EnsemblBacteria" id="ALN55461">
        <property type="protein sequence ID" value="ALN55461"/>
        <property type="gene ID" value="GLE_0102"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0102"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.106"/>
    <dbReference type="OMA" id="QVRTYRW"/>
    <dbReference type="OrthoDB" id="1105091at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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            <end position="153"/>
        </location>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="252" mass="26848" checksum="ADE1B5A17DD21411" modified="2016-02-17" version="1">MGGGRFRQAVRTRAIRLALGAALAAPACPALAAGLQVTPTQLTLGRDRPADALWLNNTGPATLRAQVRVFRWLQQDGQERLEPDPGLAVSPPMLELAPGARQLVRVIRLGAPPAQEAAYRLIVDELPPADAAQGPGLQFVLRYSVPVFLAPAAAGPIAPRLRAQLQFEDERPFLAVDNRGDQHAQLADLTFVDAQGRRHAIAAGLLGYAHAGQRMRWALQAPAALLRGPGTLEARINGEPDAQALALDPPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAM7</accession>
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        </submittedName>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 5">C3</strain>
        </source>
    </reference>
    <reference evidence="2 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">OH11</strain>
        </source>
    </reference>
    <reference evidence="3 8" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW24595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000006">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55540">
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        <property type="gene ID" value="GLE_0181"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD61643"/>
        <property type="gene ID" value="BV903_22710"/>
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    <dbReference type="Proteomes" id="UP000190203">
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    <dbReference type="Proteomes" id="UP000308311">
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    </dbReference>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="EMBL" id="OPD61643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
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            <dbReference type="EMBL" id="QCW24595.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROU08863.1"/>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="81" mass="9031" checksum="24CEACEB0ACE963D" modified="2016-02-17" version="1">MAQPKSHLEIALASIPVFTNDGTLDVTELQKLLDLALRDATVDEDEKRVLGNIFKQAELGTLDPEVQRRIDQARRQHGIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAT1</accession>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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        </subcellularLocation>
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        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
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    </dbReference>
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        </location>
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            <end position="762"/>
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        <source>
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        <source>
            <dbReference type="RuleBase" id="RU003357"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00593"/>
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            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN55553.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW24605.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="762" mass="82990" checksum="D73B4535370B7C6B" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAW3</accession>
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        </submittedName>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="199" mass="22030" checksum="58731A1CE379DACF" modified="2016-02-17" version="1">MTEPLPPASEPAARVSDAQRNRNRLTLLLIAAFFFVPMLVAGVMRFTDRHPAINRQHGELLEPKPDLRELAPSLIDGKPYPWNPGARVWRILVAPKPDCAQECVALSHELDTVWQLFGKDADQVDLLWLGEPPAGAARPASLRVLGPAPQLRERLPRLDDPAGTPVYVVDPNGFVILRYAPGFQPGGLRTDLSRLLKLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB29</accession>
    <name>A0A0S2DB29_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribonuclease BN</fullName>
            <ecNumber evidence="5">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rbn</name>
        <name evidence="5" type="ORF">GLE_0307</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
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    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
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    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017039">
        <property type="entry name" value="Virul_fac_BrkB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30213">
        <property type="entry name" value="PTHR30213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03631">
        <property type="entry name" value="Virul_fac_BrkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00765">
        <property type="entry name" value="yihY_not_rbn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="96"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="165"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="211"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="244"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="279"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN55665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="361" mass="38261" checksum="58E86FBD044B14E5" modified="2016-02-17" version="1">MPSTDPRRPDDALPRSAAAGTGRPMPGSDAQADARETIATAEPAPAPLPPSPGDAGGRSAAAGLAHDAMQRVHSLQARLEQSWPGKFVQRFVDYDILALAAALSFYTLLSLAPLVLMVLWLSTALYPSAQEEFFRQMGLLAGNEVENTARLIVANAQHRPGTGSMAAMLGTLALLVGASAVFGQLQAALNRVFRSDAKRLGGLAVWLRKRLLSFGMVISVGFLLVVSMAAQAALQLLIAYVPDLLPAFAAGFSFLLYAAVFAAMYRWLPDRPVTRRRALFGGALTAGMFMLGRSAIGLYLGQASLGTAYGPAGGLVVMLVWMYYCAVVFLVGALITAMLDEHARVRRRLADERAAAGLDAG</sequence>
</entry>
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    <accession>A0A0S2DB78</accession>
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        </submittedName>
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    <gene>
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    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946038.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0441"/>
    <dbReference type="EnsemblBacteria" id="ALN55799">
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        <property type="gene ID" value="GLE_0441"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0441"/>
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    <dbReference type="OMA" id="DFPIKQL"/>
    <dbReference type="OrthoDB" id="602613at2"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016990">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018101">
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    </dbReference>
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    </dbReference>
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            <begin position="207"/>
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            <begin position="326"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN55799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW24788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="605" mass="65540" checksum="8CF2461F153251B9" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB90</accession>
    <name>A0A0S2DB90_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta fold hydrolase</fullName>
        </submittedName>
        <submittedName>
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            <ecNumber evidence="2">3.8.1.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dhlA</name>
        <name evidence="3" type="ORF">FE772_01870</name>
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    </gene>
    <organism evidence="2 4">
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        <lineage>
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            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.8.1.5" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN55560">
        <property type="protein sequence ID" value="ALN55560"/>
        <property type="gene ID" value="GLE_0201"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="37"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="300" mass="33396" checksum="86ACD62C5CEEAC21" modified="2016-02-17" version="1">MTSSSRFPDYPFQPQRFEVRPGIGLSYLDQGPRDGEVVVMLHGNPSWSYYWRKLVLGLHDRYRCIVPDHVGMGLSDKPGDERYEYTLQSRVDDVEALLKHLNIDGPMTLAVHDWGGGIGFGWGLKHSEQIKRLVITNTGAFPLPAAKPLPKRLRLGRDSSVGTGLIRGLNAFAGGAARLGVSKPMPAEVRRAYVAPYDSWANRIATSRFVQDIPLGEGDKAWPLVQAMGRKLPEYADRPAFIGWGLGDFVFDHHFLKGFTDALPRAEVHAFKDAGHYVLEDKADELVPAVRAFLDRHPLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBE6</accession>
    <name>A0A0S2DBE6_LYSEN</name>
    <protein>
        <submittedName>
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        </submittedName>
        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lysE</name>
        <name evidence="7" type="ORF">FE772_03255</name>
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    </gene>
    <organism evidence="6 8">
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW24839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946084.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0503"/>
    <dbReference type="EnsemblBacteria" id="ALN55861">
        <property type="protein sequence ID" value="ALN55861"/>
        <property type="gene ID" value="GLE_0503"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0503"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.498"/>
    <dbReference type="OMA" id="FARPRAW"/>
    <dbReference type="OrthoDB" id="1953934at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
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    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="147"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN55861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW24839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="205" mass="21618" checksum="0FA652F7C50ACE85" modified="2016-02-17" version="1">MLSAAALAGFLASAGLIIAIGAQNAFVLRQGLARRHVGPVVAICAFSDIALILAGVAGIGALVQAWPTLLQVLRFGGAAFLGVYGFLAARRAWQGSGGLAASNAQQQTLRTAVLTCLAFTFLNPHVYLDTMVLLGSLSTRYDGDLRWAFAIGACLASVVWFASLGFGARLLQPVFRNPRAWRVLDGGIALFMWALCLMLLLQPLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBI3</accession>
    <name>A0A0S2DBI3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phospholipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_03090</name>
        <name evidence="2" type="ORF">GLE_0465</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW24807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946057.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0465"/>
    <dbReference type="EnsemblBacteria" id="ALN55823">
        <property type="protein sequence ID" value="ALN55823"/>
        <property type="gene ID" value="GLE_0465"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0465"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.461"/>
    <dbReference type="OrthoDB" id="1706469at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <begin position="31"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="428"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="449" mass="47701" checksum="063A98E5D19EFAA0" modified="2016-02-17" version="1">MSDPNPKVPKPSFADRIKGFAESFAKHSANEFDLSGTGQDLSHSAPEPPTAKPSFAFKPMAPQPVPVPTFSMPSFGASHHGSTHHGPTGRPAPLPPMPAPSSSSSGTGGIELDPLTAAAIMHDGYKDKSTRDLNGWTRVGDEELRALPQPLNPDDFHRHPSGMRADLYRKGDAYTLEFRGTQVAADWPHNISQATGYGSGQYDAAVELTEQVKASLPDGLKFVVGHSKGGGQAYVSGQANGVDSVIANPAWPHVATLEKYGVVVDASELRPKNTTLHVNGEPLTALQQLGATSLVPPHGPMIDFQPPPHVPRQSPLLRHYVEGMEPDMDMAKNIISGLDRMGYQTFIHGAKVLENACADQRAGELATLAKSQHMPQVDAIIKGEKGGGFLVCGDVRDSSAQRIHFGGAVPEGELARDTCKRINDALQANPTQTQGGAPQQAQTGPGFAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBQ2</accession>
    <name>A0A0S2DBQ2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Gammaproteobacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946156.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55963">
        <property type="protein sequence ID" value="ALN55963"/>
        <property type="gene ID" value="GLE_0605"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0605"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.597"/>
    <dbReference type="OrthoDB" id="1469401at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="327" mass="34378" checksum="7120F16F9F2C1E58" modified="2016-02-17" version="1">MTRPSSVPLKRVRIAAAIALALAAIVAVYLMGRHQGRLASHEEAAGPVAAEGRAATDTLAPAAGAPSGAALPPPGAPLKRGFAALQARADAGDAGAATRLYRDLSQCRRFARLERDVRRYSDEVMAGGDGADARSRQGSRAALEAAEANERVLDALRAQCQGVDAAMLGALVPNLHKAALLGEPYARACYLARGPGLDAAGLLDHPERLSAYRGTARTLIERGIADGDWRVLDQLRGAYEPGADSLLAAAVGDDAAQRYRYLKLFRLGAPSQPGATDEDLATAAARLGPTQLADADAWATRTFNQNFHGRRIDADGPLWDPCVFPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBV5</accession>
    <name>A0A0S2DBV5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_03915</name>
        <name evidence="2" type="ORF">GLE_0642</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946183.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0642"/>
    <dbReference type="EnsemblBacteria" id="ALN56000">
        <property type="protein sequence ID" value="ALN56000"/>
        <property type="gene ID" value="GLE_0642"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0642"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.631"/>
    <dbReference type="OrthoDB" id="2087347at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011846">
        <property type="entry name" value="Cyd_oper_YbgE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09600">
        <property type="entry name" value="Cyd_oper_YbgE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="100" mass="10355" checksum="4A4928F1418C92EF" modified="2016-02-17" version="1">MDVADAAERAAPAGGWARALSLLLAASLSLALLFLPAMRGAELGPGAHGLLTPLVAAICAGFVHGVGFRPRLAWARALLHPALLWPLMLGLAALWTRSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBX3</accession>
    <name>A0A0S2DBX3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Beta-lactamase</fullName>
            <ecNumber evidence="2 4">3.5.2.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_0645</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a beta-lactam + H2O = a substituted beta-amino acid</text>
            <dbReference type="Rhea" id="RHEA:20401"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35627"/>
            <dbReference type="ChEBI" id="CHEBI:140347"/>
            <dbReference type="EC" id="3.5.2.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the class-C beta-lactamase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.6" evidence="2 4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946185.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0645"/>
    <dbReference type="EnsemblBacteria" id="ALN56003">
        <property type="protein sequence ID" value="ALN56003"/>
        <property type="gene ID" value="GLE_0645"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0645"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.634"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008800">
        <property type="term" value="F:beta-lactamase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017001">
        <property type="term" value="P:antibiotic catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001586">
        <property type="entry name" value="Beta-lactam_class-C_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021860">
        <property type="entry name" value="Peptidase_S12_Pab87-rel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11954">
        <property type="entry name" value="DUF3471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00336">
        <property type="entry name" value="BETA_LACTAMASE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594728" description="Beta-lactamase" evidence="5">
        <location>
            <begin position="29"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="6">
        <location>
            <begin position="53"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3471" evidence="7">
        <location>
            <begin position="497"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF11954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN56003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="587" mass="60565" checksum="8A8FCAE15B43B880" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC38</accession>
    <name>A0A0S2DC38_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FE772_04355</name>
        <name evidence="10" type="ORF">GLE_0733</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0733"/>
    <dbReference type="EnsemblBacteria" id="ALN56091">
        <property type="protein sequence ID" value="ALN56091"/>
        <property type="gene ID" value="GLE_0733"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0733"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.721"/>
    <dbReference type="OMA" id="GNRFAYS"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011662">
        <property type="entry name" value="Secretin/TonB_short_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07660">
        <property type="entry name" value="STN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00965">
        <property type="entry name" value="STN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0798">TonB box</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242650" evidence="8">
        <location>
            <begin position="23"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="domain" description="STN" evidence="9">
        <location>
            <begin position="55"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="108"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN56091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW25016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="954" mass="104383" checksum="AE6593098CC5A107" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC46</accession>
    <name>A0A0S2DC46_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF2188 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_15490</name>
        <name evidence="3" type="ORF">FE772_03565</name>
        <name evidence="1" type="ORF">GLE_0570</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000040">
        <property type="protein sequence ID" value="OPD63036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946133.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55928">
        <property type="protein sequence ID" value="ALN55928"/>
        <property type="gene ID" value="GLE_0570"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63036">
        <property type="protein sequence ID" value="OPD63036"/>
        <property type="gene ID" value="BV903_15490"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0570"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.564"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018691">
        <property type="entry name" value="DUF2188"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09954">
        <property type="entry name" value="DUF2188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD63036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="87" mass="9918" checksum="EF47F1D44298E353" modified="2016-02-17" version="1">MSTLVTIYEVVSHAQRFWRLRINGSQEIAFPTRDIASAAARVRARRQNQDTGGHTEVWVQRLDGRMDREAVFLGGTAGAMCAEWRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCG3</accession>
    <name>A0A0S2DCG3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase</fullName>
            <ecNumber evidence="6">6.3.2.45</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Murein peptide ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 10" type="primary">mpl</name>
        <name evidence="10" type="ORF">GLE_0859</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + L-alanyl-gamma-D-glutamyl-meso-diaminoheptanedioate + UDP-N-acetyl-alpha-D-muramate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate</text>
            <dbReference type="Rhea" id="RHEA:29563"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61401"/>
            <dbReference type="ChEBI" id="CHEBI:70757"/>
            <dbReference type="ChEBI" id="CHEBI:83905"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.45"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cell wall biogenesis; peptidoglycan recycling.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MurCDEF family. Mpl subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.45" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946351.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0859"/>
    <dbReference type="EnsemblBacteria" id="ALN56217">
        <property type="protein sequence ID" value="ALN56217"/>
        <property type="gene ID" value="GLE_0859"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0859"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.848"/>
    <dbReference type="OMA" id="SGIAWDH"/>
    <dbReference type="OrthoDB" id="307881at2"/>
    <dbReference type="UniPathway" id="UPA00544"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106418">
        <property type="term" value="F:UDP-N-acetylmuramate-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009254">
        <property type="term" value="P:peptidoglycan turnover"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02020">
        <property type="entry name" value="Mpl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005757">
        <property type="entry name" value="Mpl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01081">
        <property type="entry name" value="mpl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 6" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 6" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5 6" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 6" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="7">
        <location>
            <begin position="3"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="9">
        <location>
            <begin position="108"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="8">
        <location>
            <begin position="314"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="110"/>
            <end position="116"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN56217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="454" mass="48582" checksum="89C19929047CBC14" modified="2016-02-17" version="1">MKLHILGIAGTFMGGVAALARELGHDVEGSDQTVYPPMSTQLERLGIALRQGYTPDNISADCDEIVVGNALSRGNPAVEQVLDDGRRYTSGAQWLSERVLPGRDTLAVAGTHGKTTTTTILTWLLEAAGRAPGFLIGGVAEDFGASARIGAGREFVVEADEYDTAFFDKRSKFVHYRPLVAILNNLEYDHADIFPDVAAIQRQFHHLVRTVPRRGRLIVNGEDARLAEVLAMGCWTPVERFGLDGGDYEWSARLIEADGSAFALLHRGAEIGEVRWPLLGRHNVMNALAALAAAHAVGVDVAAVLPALANFRSVKRRLEVIGEAAGVTVYDDFAHHPTAIETTLAGLRARVGAARIVVAMEPRSNSMRLGAHADALAPSLREADTVVFLHRPELAWDAGKVVAGLRGEGVAVADADALIAALRERARAGDHVVFMSNGGFDGAPRRFFAALQGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCG5</accession>
    <name>A0A0S2DCG5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0848</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946342.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56206">
        <property type="protein sequence ID" value="ALN56206"/>
        <property type="gene ID" value="GLE_0848"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0848"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.836"/>
    <dbReference type="OrthoDB" id="1929841at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="194" mass="20523" checksum="34A25EBA44ABA67E" modified="2016-02-17" version="1">MKPAAPPTAPAASAPQAAGAETTIQGPNGVRIEVRFDYRASSRLARIDYRLHNPAAAPPLAVFDRGDLHQVRIGRQKLGAIGQPGFVEQNGDVEILHAAMPLPDPAPTSPPTPLAAKVAPGATLAGAFQTQIWSEAEPKRLRWCVGVMPFEASFFDAPAKTADGEVWSAPFSAADAQQMLCTPWFDVAKGAFEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCL9</accession>
    <name>A0A0S2DCL9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">IS30 family transposase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">ISMsm8, transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_05225</name>
        <name evidence="5" type="ORF">GLE_0915</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the transposition of the insertion element.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transposase IS30 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946392.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56273">
        <property type="protein sequence ID" value="ALN56273"/>
        <property type="gene ID" value="GLE_0915"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0915"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.903"/>
    <dbReference type="OMA" id="MFHHERI"/>
    <dbReference type="OrthoDB" id="1780129at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025246">
        <property type="entry name" value="IS30-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001598">
        <property type="entry name" value="Transposase_IS30_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13936">
        <property type="entry name" value="HTH_38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01043">
        <property type="entry name" value="TRANSPOSASE_IS30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="4">
        <location>
            <begin position="188"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="154"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW25156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="353" mass="40649" checksum="4DFFAADF3FEC0156" modified="2016-02-17" version="1">MGQQYSHLSAEERGAIMVLIAQGASGRQIAQTLGRAQSTIARELRRNGYRSDLAAPLRGRPRLEPDYDATRAGRRAQRLRRRARVRRKLRRDTVLWRRVRYWLERCWSPQQIADKLRDLYPDRPWLRVSHETIYTAIYAMPRGELRRQVTRLLRQGRKSGRRTRQGSDARGHLPDLPNIRLRPPAAHERLMPGHWEGDLIVGAHNRSAIGVLVCRRTLYVKLVKLADATAHTVLEAFSSAFEGVPESLKKTLTYDQGKEMASHRQLSERTGLAIYFADPHSPWQRGTCENTNGLLRQYFPKGTDLSVHSAQRLKEVAWEMNNRPRRSLGRRSPVEVLYEELKKPRAQGDALGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD66</accession>
    <name>A0A0S2DD66_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_1120</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1120"/>
    <dbReference type="EnsemblBacteria" id="ALN56478">
        <property type="protein sequence ID" value="ALN56478"/>
        <property type="gene ID" value="GLE_1120"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1120"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1106"/>
    <dbReference type="OMA" id="SIPYQFN"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025392">
        <property type="entry name" value="DUF4124"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13511">
        <property type="entry name" value="DUF4124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594850" evidence="1">
        <location>
            <begin position="26"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4124" evidence="3">
        <location>
            <begin position="16"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="2">
        <location>
            <begin position="188"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="314" mass="33822" checksum="DE8717D6F9D731AA" modified="2016-02-17" version="1">MPRPTSLIVPSLILAATLAVPAAQAGKLYRWTDRNGVTHYGDRAPSDAVAAAAGAAEVKVIPYRSEPGSIARLRVQQDGDRYLAWADNSLAGPIEVRLDFNHSNNIIGSPLLPASATLDPRASAVVSVLSAQDPSRGGDFELSMRSVPGDPRARPQNADYLLPLRQQQFRIDQGYGGHFSHSEPEHRYAVDFAADIGTPVLAARDGTVMQVESDFDKAGLNLEKFGDRANFVRILHDDGTMALYAHLKADDGVMVRVGQRVRAGQQIGLSGNTGFSTGPHLHFAVQVNRGMRLESIPFRMTGPQGPLRLGGSVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD94</accession>
    <name>A0A0S2DD94_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_06025</name>
        <name evidence="2" type="ORF">GLE_1094</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946521.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56452">
        <property type="protein sequence ID" value="ALN56452"/>
        <property type="gene ID" value="GLE_1094"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1094"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1081"/>
    <dbReference type="OrthoDB" id="1843642at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="127" mass="14349" checksum="BD650D90F1AC3D73" modified="2016-02-17" version="1">MTATPWIYLAGLHSLGFAVFHMAFWRIFRWRDTLRTATVADRAIIQILNLRLIYIASGVAALCFLFADELHSTALGRAVLLGMSLFWVGRTIEQFVFLRINRPMVHALTALFVLGAVLFAVPLWMPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-06-17" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDA3</accession>
    <name>A0A0S2DDA3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1113</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56471">
        <property type="protein sequence ID" value="ALN56471"/>
        <property type="gene ID" value="GLE_1113"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1113"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1099"/>
    <dbReference type="OrthoDB" id="2040275at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594956" evidence="2">
        <location>
            <begin position="26"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="200" mass="21727" checksum="C7F1E6D5F9491011" modified="2016-02-17" version="1">MNGFRSLRPHRAAFAGALVLTLSLAACDRAAPPEETAPVAAAPSAPPDLTQGPATATISADGRTLSVGVPERSLEETAAKFFNQRADRFDSVAILAQGKRDDVYQVLVRAEAASDPKRDGGRCRDGREVKLRHLEFDLSSMSMTSSQDLESCLRRLRVVAQRRLADGGFEYDLEEIDADGDPSSMYLRYDGKDYGRPAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDE5</accession>
    <name>A0A0S2DDE5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BolA family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">BolA family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">BolA/IbaG family iron-sulfur metabolism protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_16420</name>
        <name evidence="6" type="ORF">D9T17_21135</name>
        <name evidence="5" type="ORF">FE772_06510</name>
        <name evidence="3" type="ORF">GLE_1198</name>
    </gene>
    <organism evidence="3 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">C3</strain>
        </source>
    </reference>
    <reference evidence="4 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">OH11</strain>
        </source>
    </reference>
    <reference evidence="5 10" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 10">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the BolA/IbaG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000043">
        <property type="protein sequence ID" value="OPD62863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000053">
        <property type="protein sequence ID" value="ROU04946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946592.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000053.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1198"/>
    <dbReference type="EnsemblBacteria" id="ALN56556">
        <property type="protein sequence ID" value="ALN56556"/>
        <property type="gene ID" value="GLE_1198"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62863">
        <property type="protein sequence ID" value="OPD62863"/>
        <property type="gene ID" value="BV903_16420"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1198"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1183"/>
    <dbReference type="OMA" id="HQLVYGA"/>
    <dbReference type="OrthoDB" id="2009812at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002634">
        <property type="entry name" value="BolA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036065">
        <property type="entry name" value="BolA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01722">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003113">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82657">
        <property type="entry name" value="SSF82657"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD62863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROU04946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="78" mass="8322" checksum="434C27A1BC720B1F" modified="2016-02-17" version="1">MNADTIRSLIEQGLPGAQAQVRGDDGVHFEATVVAEAFRGKLPLARHRLVYATLGERMGGEIHALALKTLTPEEAGQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDE8</accession>
    <name>A0A0S2DDE8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Na+ dependent nucleoside transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="11">Na+ dependent nucleoside transporter domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="12">NupC/NupG family nucleoside CNT transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BV903_03845</name>
        <name evidence="12" type="ORF">FE772_05855</name>
        <name evidence="10" type="ORF">GLE_1055</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">C3</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000007">
        <property type="protein sequence ID" value="OPD65236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946492.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1055"/>
    <dbReference type="EnsemblBacteria" id="ALN56413">
        <property type="protein sequence ID" value="ALN56413"/>
        <property type="gene ID" value="GLE_1055"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65236">
        <property type="protein sequence ID" value="OPD65236"/>
        <property type="gene ID" value="BV903_03845"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1055"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1044"/>
    <dbReference type="OMA" id="IVWHTVI"/>
    <dbReference type="OrthoDB" id="437016at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Nucleos_tra2_C"/>
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    </dbReference>
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        <property type="entry name" value="Nucleos_tra2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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        </location>
    </feature>
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    </feature>
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            <end position="431"/>
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        <location>
            <begin position="208"/>
            <end position="425"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00009033"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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            <dbReference type="Pfam" id="PF07662"/>
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            <dbReference type="Pfam" id="PF07670"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN56413.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="OPD65236.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW25253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="432" mass="45025" checksum="3FF6BEC225D2AEB8" modified="2016-02-17" version="1">MDSISRVGFGLFGLAVLVAIAWVFSVNRRKVDWKLVAIGITLQIAFAAVVLLVPGGKDVFDAIGKGFVHVLEFVGAGSKFIFGDLMDVSKFGFIFAFQVLPTIIFFSALMGVLYHLGVMQAVVRGMAWAITKVMRVSGAETTSVCASVFIGQTEAPLTVRPYIPKMTESELITMMIGGMAHIAGGVLAAYVGMLGAGDPESQAFYAKHLLAASIMAAPATLVIAKILVPETGEPLTRGTIKMEVEKNTANIIDAAAAGAGDGLRLALNIGAMLLAFIALMALINAPLTWIGEHTGLAAAIGKPTDLSTILGFVLAPIAWVIGTPWADANVVGGLIGEKVVLNEFVAYTHLADIVNGKVAGVSLSDEGRLIATYALCGFANFSSIAIQIGGIGGLAPERRQDLARFGLRAVLGGSIATFMTATIAGVLTHFAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDI8</accession>
    <name>A0A0S2DDI8_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">DUF4198 domain-containing protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">FE772_06730</name>
        <name evidence="2" type="ORF">GLE_1245</name>
    </gene>
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        <name type="scientific">Lysobacter enzymogenes</name>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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    <dbReference type="EnsemblBacteria" id="ALN56602">
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    <dbReference type="Proteomes" id="UP000308311">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
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            <begin position="23"/>
            <end position="269"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="269" mass="28889" checksum="8391F0CA9BA5DE00" modified="2016-02-17" version="1">MKTKLVLATALAALALAGSAHAHKAWLQPSQTVFSDKGSWMTVDAAVSNDLFYFNHVPLPLERLQVTAPDGSSVAPQNGATGKLRSVFDLQLQQEGTYKIAMNNEGMFASYKLGGEAKRWRGKASEFKGAIPAGATEVNASESLGRVETFATVGKPSTSVFKTTGKGIELVPVTHPNDLFAGEAATFQLLIDGKPASGLKIEVVPGATRYRNEQAEILVTTGADGKFEVKWPQAGMYWLETASEDAKTTLPDAKQRRLSYVAVFEVLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDK5</accession>
    <name>A0A0S2DDK5_LYSEN</name>
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        <submittedName>
            <fullName evidence="10">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FE772_06535</name>
        <name evidence="10" type="ORF">GLE_1203</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW25370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946595.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1203"/>
    <dbReference type="EnsemblBacteria" id="ALN56561">
        <property type="protein sequence ID" value="ALN56561"/>
        <property type="gene ID" value="GLE_1203"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1203"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1188"/>
    <dbReference type="OMA" id="YSRSGAN"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010917">
        <property type="entry name" value="TonB_rcpt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01156">
        <property type="entry name" value="TONB_DEPENDENT_REC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726642" evidence="7">
        <location>
            <begin position="24"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="60"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="275"/>
            <end position="748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN56561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW25370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="751" mass="82499" checksum="7F2345D0EF937CEF" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDM0</accession>
    <name>A0A0S2DDM0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FeS assembly ATPase SufC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">sufC</name>
        <name evidence="6" type="ORF">GLE_1258</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. Ycf16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1258"/>
    <dbReference type="EnsemblBacteria" id="ALN56615">
        <property type="protein sequence ID" value="ALN56615"/>
        <property type="gene ID" value="GLE_1258"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1258"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1242"/>
    <dbReference type="OMA" id="MAMLEPK"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03217">
        <property type="entry name" value="ABC_FeS_Assembly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010230">
        <property type="entry name" value="FeS-cluster_ATPase_SufC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43204">
        <property type="entry name" value="PTHR43204"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="sufC"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="12"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN56615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="264" mass="28682" checksum="C28B9F944AD56EE0" modified="2016-02-17" version="1">MTTESTKNPAMLKIENLHVSVAGKEILKGLTLELIPGQVHAIMGPNGAGKSTLGNVLAGREGYEVTAGSVEFDGRDLLALEPEERAAAGVFLAFQYPVEIPGVNNTYFLRAALNAQRKARGEAELDSMQFLKLVREKLAVLHLKDELLHRGVNEGFSGGEKKRNEIFQLALLEPRLAILDETDSGLDIDALKAVADGVNALRSPERAFLVITHYQRLLDYIKPDVVHVLADGRIVETGGAELALELEAHGYAWLKDRVAPQSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDM3</accession>
    <name>A0A0S2DDM3_LYSEN</name>
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        <submittedName>
            <fullName evidence="4">Sporulation and cell division repeat protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Sporulation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_07125</name>
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    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
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        </lineage>
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    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="QCW25469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1337"/>
    <dbReference type="EnsemblBacteria" id="ALN56694">
        <property type="protein sequence ID" value="ALN56694"/>
        <property type="gene ID" value="GLE_1337"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1337"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1319"/>
    <dbReference type="OMA" id="MQARESH"/>
    <dbReference type="OrthoDB" id="1408120at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042834">
        <property type="term" value="F:peptidoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007730">
        <property type="entry name" value="SPOR-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036680">
        <property type="entry name" value="SPOR-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05036">
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        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
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            <end position="191"/>
        </location>
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    <feature type="domain" description="SPOR" evidence="3">
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            <end position="365"/>
        </location>
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        <location>
            <begin position="33"/>
            <end position="96"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="289"/>
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            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="367" mass="37202" checksum="7D2B139A3718B5F5" modified="2016-02-17" version="1">MEPALKQRLIGALVLVALAVIFLPMLIKGPAPESGASDVPLTLPDQPQGGQGETRELPLVTPGDAPQDGMVGMERPQPEPGAAAPAGNGQTLPTVDTAAGRQGMQPAAAAGGDYAVSFGSYASAGDADRVIAALQAARLPGYQETAAGANGRTVYRVRIGPFATQADAEAARLNSTKVRNDINAKVVVLNADAADLASGPAPAPAKPASTPAPLNDTKPAKPAALPPEPAKPVAAKPAEPKPTEPKPAKPADTKPVAAAKPVETKPLEPAKPVEKPAAKPEPAKPAAAGTGFAVQLGAFGNAEEANKLRDRARAAGFSAFVEQVRTDKGTLNRVRIGPVVNRADADKLKGQVGSKLGIGDALVKPHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDR4</accession>
    <name>A0A0S2DDR4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1401</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56758">
        <property type="protein sequence ID" value="ALN56758"/>
        <property type="gene ID" value="GLE_1401"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="41" mass="4363" checksum="16B550B5957E7F4B" modified="2016-02-17" version="1">MSDCRSCASCGCDTALATQAMAARSKPAPPCKKRRCLITCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDZ3</accession>
    <name>A0A0S2DDZ3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4440 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1364"/>
    <dbReference type="EnsemblBacteria" id="ALN56721">
        <property type="protein sequence ID" value="ALN56721"/>
        <property type="gene ID" value="GLE_1364"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1364"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1346"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027843">
        <property type="entry name" value="DUF4440"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14534">
        <property type="entry name" value="DUF4440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4440" evidence="1">
        <location>
            <begin position="16"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="156" mass="17318" checksum="67097858DCDBEE68" modified="2016-02-17" version="1">MDAAPRLSAEECAVWARELGFARALAEHDAAAFAAFVHPQAAFGAGQPQPTRGREAIAAQWADLIAGKRLRLRWYPQRVTVAGVGDVAWSTGPALYQRIDPGAQPRYLIGQYQSVWRRDTDGVWRVLFDDGIAPRPATEAEAMAFERGRREDCPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEC5</accession>
    <name>A0A0S2DEC5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF1963 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_08440</name>
        <name evidence="3" type="ORF">GLE_1625</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946930.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56982">
        <property type="protein sequence ID" value="ALN56982"/>
        <property type="gene ID" value="GLE_1625"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1625"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1606"/>
    <dbReference type="OMA" id="GMLQFFI"/>
    <dbReference type="OrthoDB" id="1878535at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015315">
        <property type="entry name" value="DUF1963"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035948">
        <property type="entry name" value="YwqG-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09234">
        <property type="entry name" value="DUF1963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103032">
        <property type="entry name" value="SSF103032"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="348" mass="36667" checksum="903F3DB1E98F6F73" modified="2016-02-17" version="1">MNTGKAVLLSAAIVAAMLGAVGGGLYLLDRRIKQAGGHTMTIPLPGGEAGKTGAPRGSKASASRCGQDDGDDCLAKAALAPAAPALERSRRAVARIALEPMAADELKASKVGGRAYWAAGREYPRDPQGRALSLLAQIDLAAAPKMPGYPARGLLQFFVDGDDYYGAALDAADRGDRMRALAQQKGFRVVYWADAAAPAVAVPAGANSESLPFDPAKPRRMRFSADSESIGASDVGIGAALGGDPTDLAAQYLRDHPGAAGSGADLSDEDLNERIADYLDRSGHKLGGHPQFTQSDPRVSGDRRVLLFQLDSDDEMMWGDSGIANFFIDPDDLARADFSRVSYHWDCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEI1</accession>
    <name>A0A0S2DEI1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cation diffusion facilitator family transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Cation transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_08435</name>
        <name evidence="7" type="ORF">GLE_1624</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946929.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1624"/>
    <dbReference type="EnsemblBacteria" id="ALN56981">
        <property type="protein sequence ID" value="ALN56981"/>
        <property type="gene ID" value="GLE_1624"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1624"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1605"/>
    <dbReference type="OMA" id="HMRTLHL"/>
    <dbReference type="OrthoDB" id="381612at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006829">
        <property type="term" value="P:zinc ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040177">
        <property type="entry name" value="SLC30A9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13414">
        <property type="entry name" value="PTHR13414"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="SSF160240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="SSF161111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN56981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW25690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="304" mass="33097" checksum="51E7F26286293887" modified="2016-02-17" version="1">MAGGGDSTRAILFALGANFAIAVAKGVAAFFTGSSAMLAETVHSLADCGNQGLLILGLKQAKRPPSPDYPLGYGKAIYFWSFLVAVMLFTVGGMFSLYEGIHKLQHPEPLKQWWWAAGVLAFGIVAEAISMRACLQEVDKARGQRSLWQWFRESRQAELVVIFGEDLAALLGLVLALGAVMMTVVTGNPIWDAIGTVSIGALLIIVAVFVAIEVKAMLIGQSVDPLRQQQIREFLDARPEIARVISLITLQLGNEVMVSVQAQMREEHSVAGLTEQINTVERAMKQAFPEVRWSFFEPDHKPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEM3</accession>
    <name>A0A0S2DEM3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cell division protein FtsB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 7" type="primary">ftsB</name>
        <name evidence="6" type="ORF">BV903_21670</name>
        <name evidence="7" type="ORF">FE772_07815</name>
        <name evidence="5" type="ORF">GLE_1489</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of a complex composed of FtsB, FtsL and FtsQ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <text evidence="3">Localizes to the division septum.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FtsB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000072">
        <property type="protein sequence ID" value="OPD61787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1489"/>
    <dbReference type="EnsemblBacteria" id="ALN56846">
        <property type="protein sequence ID" value="ALN56846"/>
        <property type="gene ID" value="GLE_1489"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61787">
        <property type="protein sequence ID" value="OPD61787"/>
        <property type="gene ID" value="BV903_21670"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1489"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1470"/>
    <dbReference type="OMA" id="PRIKTKA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00599">
        <property type="entry name" value="FtsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023081">
        <property type="entry name" value="Cell_div_FtsB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007060">
        <property type="entry name" value="FtsL/DivIC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37485">
        <property type="entry name" value="PTHR37485"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04977">
        <property type="entry name" value="DivIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 6" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="topological domain" description="Cytoplasmic" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="topological domain" description="Periplasmic" evidence="3">
        <location>
            <begin position="32"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="100"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="39"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD61787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW25587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="160" mass="16761" checksum="9A78CF863B0F51A2" modified="2016-02-17" version="1">MAEKSRKAWLGVVALALLALLAALQYRLWWAGGGGGGSVAALQAQVDGQTRENQGLQQRNDALAAEVEDLKSGEAAVEERARSELGMIKPGETFYRVVEARPQPPGPNAAAAVNAVQNGAAAGQDAADEEPSLEEQVDEPPTEVPPSTPEPHPMPAPVQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEV5</accession>
    <name>A0A0S2DEV5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_09025</name>
        <name evidence="2" type="ORF">GLE_1753</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947026.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1753"/>
    <dbReference type="EnsemblBacteria" id="ALN57108">
        <property type="protein sequence ID" value="ALN57108"/>
        <property type="gene ID" value="GLE_1753"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1753"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1729"/>
    <dbReference type="OMA" id="YVPYCTG"/>
    <dbReference type="OrthoDB" id="1074190at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004963">
        <property type="entry name" value="PAE/NOTUM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21562">
        <property type="entry name" value="PTHR21562"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03283">
        <property type="entry name" value="PAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242153" evidence="1">
        <location>
            <begin position="27"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="467" mass="50756" checksum="A37866CC61972458" modified="2016-02-17" version="1">MAALSRYVAVALVGGAVAFSSLPSQAEQGDYGFFQTLKNLVSPPKPDNKVQPKQRTGQYPLLSADAGRASGFDPGAYYQWQTVQLPAETGAICGNGSPYKIFVNRVPDTTNTIIYMEGGGACWDYASCTGATGVRGARNPNGVPDDYMKLLNPGASLVSPFVTRVSPFDAVKTQGWNMVYVPYCTGDIYSGDKVAVYDDPSGQKPPLVWHHNGLRNTRAIIAWLKDNLPRPGQMLNTGCSAGGAGSLISYDTFRTDVAPTQGFLIDDSGPIFPTPKNANPAEYPSQPLMTKIRDVWGLDAPNGPLAFLAAGLPQMDLNELGSIYPALSSKHTGDRLGHTHFWQDLNYSSYSYERFHDDIAQAPNQAAKEALIHAKWGTDTQRLSARLNGLDNFGGYFPQYRALNESHCTTIVDFKNGDVQAQNLELKNFIDSVLDGNGKVLDASETSDAADKAKPFNFLYWLVDQLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF28</accession>
    <name>A0A0S2DF28_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_12610</name>
        <name evidence="3" type="ORF">FE772_08175</name>
        <name evidence="1" type="ORF">GLE_1568</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000031">
        <property type="protein sequence ID" value="OPD63556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946883.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000031.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56925">
        <property type="protein sequence ID" value="ALN56925"/>
        <property type="gene ID" value="GLE_1568"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63556">
        <property type="protein sequence ID" value="OPD63556"/>
        <property type="gene ID" value="BV903_12610"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1568"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1548"/>
    <dbReference type="OrthoDB" id="1570803at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD63556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="151" mass="16644" checksum="47BF15778DA076D6" modified="2016-02-17" version="1">MAEHHFQLVPVDPRFYPAPDAIDTAQAVVRALIPSAEEVHASCRPGIHFFDAGEGFEEPKCPFCDADTAPWWSDAMSDAWDGTHFNELRITTPCCGASTSLDQLRYPNGDRFGSFIIEAALADPAENPSSEQISQLQSILGCQLVAYWITR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFL2</accession>
    <name>A0A0S2DFL2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_13495</name>
        <name evidence="4" type="ORF">FE772_09070</name>
        <name evidence="2" type="ORF">GLE_1762</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000034">
        <property type="protein sequence ID" value="OPD63438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947033.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57117">
        <property type="protein sequence ID" value="ALN57117"/>
        <property type="gene ID" value="GLE_1762"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63438">
        <property type="protein sequence ID" value="OPD63438"/>
        <property type="gene ID" value="BV903_13495"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1762"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1738"/>
    <dbReference type="OrthoDB" id="2203736at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594947" evidence="1">
        <location>
            <begin position="31"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="76" mass="8229" checksum="1987FE25EB62A3D7" modified="2016-02-17" version="1">MNTRNRSIRLRLGAFALAAFGFAATMTATAAGFGCDHCLPEYYGCRDAGGDYDSCVNAFWQCQTSNGCMISLPPEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFS2</accession>
    <name>A0A0S2DFS2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1846</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947091.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57198">
        <property type="protein sequence ID" value="ALN57198"/>
        <property type="gene ID" value="GLE_1846"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1846"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1817"/>
    <dbReference type="OMA" id="WMFPNVD"/>
    <dbReference type="OrthoDB" id="1096413at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042171">
        <property type="entry name" value="Acyl-CoA_hotdog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="282" mass="30815" checksum="D7B0CE50BBA188F5" modified="2016-02-17" version="1">MSAADRPHDDDTPWYFEPLGGLRFAPSAHVGGGWNPREQHIAPAFGLLTHLIERHRDQRRDDGLVLGRLCFDIHGVLPMAPFEVELEVIRPGRTIERVEARIVHGGRTAVVLHAWLLARTDTAALAGTPEPPLPAPEQLPPWDFGSVWPGGFVRSVRARRREQAPGRCVFWVDTDVALLQGETVSPTARLLGLVDIANGATPRVAPERAVFPNLDLTAHLLRAPVGAWIGFDTSVSFGPDGIGLTHSWVHDERGLVGTVSQCLTVRPVAVQPGRSYKGARRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGM2</accession>
    <name>A0A0S2DGM2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2434</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57783">
        <property type="protein sequence ID" value="ALN57783"/>
        <property type="gene ID" value="GLE_2434"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2434"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2396"/>
    <dbReference type="OMA" id="MYEPSIC"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009594">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06719">
        <property type="entry name" value="AraC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="196"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="316" mass="34698" checksum="440259D2BF11A3D0" modified="2016-02-17" version="1">MSATDSTARRARMVELVARLAPGEGYTRSRLDSVSLMRCERPVQRTPALYEPSIVIVVQGRKRAFHNDRAYVYDAQHYLALAVPLPFETETEASADEPMFGIALRIDPSAIAELALSLDRMRPDSEVPPATMVASPMDERMSDAAVRLLEALCDPAESALLAPAIAREIAFLALTGEQGGSLRAAMAQGGHFGRIAKALRRIHDQYDRKLDVTSLAGEASMSVPAFHARFKAVTAASPIQYIKAMRLHQARLLMIRNGCAAADAARRVGYESASQFNREFKRMFGRPPLEEARELQRILRVSEPVQATAGRAASSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGQ8</accession>
    <name>A0A0S2DGQ8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Undecaprenyl-phosphate glucose phosphotransferase</fullName>
            <ecNumber evidence="9">2.7.8.-</ecNumber>
            <ecNumber evidence="11">2.7.8.31</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BV903_01350</name>
        <name evidence="11" type="ORF">FE772_12270</name>
        <name evidence="9" type="ORF">GLE_2455</name>
    </gene>
    <organism evidence="9 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">C3</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial sugar transferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.-" evidence="9"/>
    <dbReference type="EC" id="2.7.8.31" evidence="11"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000003">
        <property type="protein sequence ID" value="OPD65675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947550.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2455"/>
    <dbReference type="EnsemblBacteria" id="ALN57804">
        <property type="protein sequence ID" value="ALN57804"/>
        <property type="gene ID" value="GLE_2455"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65675">
        <property type="protein sequence ID" value="OPD65675"/>
        <property type="gene ID" value="BV903_01350"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2455"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2417"/>
    <dbReference type="OMA" id="RPHALQH"/>
    <dbReference type="OrthoDB" id="1759731at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003362">
        <property type="entry name" value="Bact_transf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017475">
        <property type="entry name" value="EPS_sugar_tfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017473">
        <property type="entry name" value="Undecaprenyl-P_gluc_Ptfrase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02397">
        <property type="entry name" value="Bac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03025">
        <property type="entry name" value="EPS_sugtrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03023">
        <property type="entry name" value="WcaJ_sugtrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_transf" evidence="8">
        <location>
            <begin position="287"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN57804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD65675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW26324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="481" mass="53526" checksum="9B5D8127CB2892BB" modified="2016-02-17" version="1">MRLGFSSALFAFARPSALRNIVALARLAHFLIVFGAGALALHALQGGPPRASEHYLALSALAGALCVLVFHSFGLYGHDMFGSRLLIRRTLLAWGAAFGLVMTLHLLFRFLRPLPDGSLALWFALSFVLFVGGRLVMLWLFQRRIRQGAFIQRSVILGMTDNALRLAEQIHHRADVVSGLVGYIDDRRTHRLSEPPPSSLPRLGDIDDLERLIRDGGVDQVLVALPAQARGRNEDLAQRLRRLPVQVLLVPDMGSFHFAHRKLVPVAGVPMFVIAEPPLQGWAPVLKRAEDLALSALALLALAPLMALVALAVKLDSPGPVLFRQKRYGYNQRLIEVFKFRSMHHHLRDEHAARQTGRADPRVTRVGRFIRKTSLDELPQLFNVLAGSMSLVGPRPHATATKAANVLFEDAVQEYVARHRVKPGITGLAQINGYRGETDTIEKIQRRVEYDLEYIENWSLWLDLSILLRTLPAVLSAEAAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGX6</accession>
    <name>A0A0S2DGX6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2546</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57895">
        <property type="protein sequence ID" value="ALN57895"/>
        <property type="gene ID" value="GLE_2546"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2546"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="74" mass="8289" checksum="56566DA1BDD31940" modified="2016-02-17" version="1">MDGSGHEETCRKVGAAVAARPRASGHGGVRGGGGYVRWIRRARPRRPQDEFRVRPHRSRRDGGSVPRRARRFAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGZ4</accession>
    <name>A0A0S2DGZ4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2313</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_2313"/>
    <dbReference type="EnsemblBacteria" id="ALN57662">
        <property type="protein sequence ID" value="ALN57662"/>
        <property type="gene ID" value="GLE_2313"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2313"/>
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    <dbReference type="OMA" id="HFEVCYY"/>
    <dbReference type="OrthoDB" id="891566at2"/>
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        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
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        <property type="entry name" value="FemAB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04339">
        <property type="entry name" value="FemAB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="408" mass="46068" checksum="0B1CFD8F2A5ED5B0" modified="2016-02-17" version="1">MSEAGDAYAVRLLGALADVPAAQWDALHDGANPFLAHAFLHGLEATGCLREDWGWTPHHLSVWRGEHLVAAMPAYLKQNSHGEFVFDHAWARAYEQHGLDYYPKWLAAVPYSPVTGPRLLAREPEHRRLLLQAMTQLCERQELSSAHVNFHREDEDAAFAAEGDGAWLQRVDVQYHWRNPADPHGLRWRDFDQFLAAFDHKHRKNIRQERAKVARAGVVFRTVEGAQASDADLATMYGFYRSTFDQYGNHAALTLDFLRHLARTMPRALVMFLAEYEGEPVAGALCLRGDDTLYGRYWGAHAQLPGLHFETCYYQGIEYCLREGLHAFEPGAQGEHKLARGFLPAEVRSRHWIAHPAFRDALRPWCREEAASIRRYAATLRAHSPFKAEAADAAADDDAPPDRPSSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH79</accession>
    <name>A0A0S2DH79_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_11420</name>
        <name evidence="1" type="ORF">GLE_2266</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
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    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW26190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947411.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57615">
        <property type="protein sequence ID" value="ALN57615"/>
        <property type="gene ID" value="GLE_2266"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2266"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2231"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="103" mass="11334" checksum="16B14F161E2B9093" modified="2016-02-17" version="1">MGYEYDLVPDDPDDYLRRRAALIDAATALPSFSRRAGAWELWLSDPARPADGWEQAQLVFGERDVRVTCMTPLSAMVRADLRALPGLFGGARYVDDDGGPAAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHF5</accession>
    <name>A0A0S2DHF5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methionine synthase</fullName>
            <ecNumber evidence="5">2.1.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">5-methyltetrahydrofolate--homocysteine methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">metH</name>
        <name evidence="15" type="ORF">FE772_13500</name>
        <name evidence="14" type="ORF">GLE_2695</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">C3</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:11172"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="2.1.1.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 7">
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (MetH route): step 1/1.</text>
    </comment>
    <comment type="domain">
        <text evidence="5">Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the vitamin-B12 dependent methionine synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.13" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947743.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2695"/>
    <dbReference type="EnsemblBacteria" id="ALN58043">
        <property type="protein sequence ID" value="ALN58043"/>
        <property type="gene ID" value="GLE_2695"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2695"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2654"/>
    <dbReference type="OMA" id="ADCIAMS"/>
    <dbReference type="OrthoDB" id="118138at2"/>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00081"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008705">
        <property type="term" value="F:methionine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042558">
        <property type="term" value="P:pteridine-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02069">
        <property type="entry name" value="methionine_synthase_B12_BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.196.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003759">
        <property type="entry name" value="Cbl-bd_cap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033706">
        <property type="entry name" value="Met_synthase_B12-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011822">
        <property type="entry name" value="MetH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036594">
        <property type="entry name" value="Meth_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004223">
        <property type="entry name" value="VitB12-dep_Met_synth_activ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037010">
        <property type="entry name" value="VitB12-dep_Met_synth_activ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02607">
        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02965">
        <property type="entry name" value="Met_synt_B12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000381">
        <property type="entry name" value="MetH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01018">
        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47644">
        <property type="entry name" value="SSF47644"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="SSF51717"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56507">
        <property type="entry name" value="SSF56507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02082">
        <property type="entry name" value="metH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50974">
        <property type="entry name" value="ADOMET_ACTIVATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51337">
        <property type="entry name" value="B12_BINDING_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="4 5 6" id="KW-0170">Cobalt</keyword>
    <keyword evidence="5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="5 8 14" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 8 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Pterin-binding" evidence="10">
        <location>
            <begin position="25"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="B12-binding N-terminal" evidence="13">
        <location>
            <begin position="317"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="B12-binding" evidence="12">
        <location>
            <begin position="417"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="domain" description="AdoMet activation" evidence="11">
        <location>
            <begin position="568"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="region of interest" description="Methylcob(III)alamin binding" evidence="7">
        <location>
            <begin position="427"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="686"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="7">
        <location>
            <begin position="884"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="361"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="430"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
        <ligandPart>
            <name>Co</name>
            <dbReference type="ChEBI" id="CHEBI:27638"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="475"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="479"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="531"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="618"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="829"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000381-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000381-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN58043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW26525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="922" mass="102106" checksum="BE9AD8087B51CE8D" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHJ9</accession>
    <name>A0A0S2DHJ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Flagellar rod assembly protein/muramidase FlgJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_14000</name>
        <name evidence="3" type="ORF">GLE_2803</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947826.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2803"/>
    <dbReference type="EnsemblBacteria" id="ALN58151">
        <property type="protein sequence ID" value="ALN58151"/>
        <property type="gene ID" value="GLE_2803"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2803"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2760"/>
    <dbReference type="OrthoDB" id="1779712at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002901">
        <property type="entry name" value="MGlyc_endo_b_GlcNAc-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01832">
        <property type="entry name" value="Glucosaminidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00047">
        <property type="entry name" value="LYZ2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0282">Flagellum</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LYZ2" evidence="2">
        <location>
            <begin position="2"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="390" mass="42151" checksum="4573B25EF88C4478" modified="2016-02-17" version="1">MGNKEEFIADLYPAAVRVSKQTGMSAELILAQAALETGWGEKVLPGTNNIFNIKDSKGWDGPSKTFNVWEIEGGKKVWKDQDFRVYGSIDEALTDRVKFLKENSRYTKAGLFEEGTLGNLEKEAKALQKAGYATDPHYAEQLAKVFNGPTMRRGIALAESRGAPELSEHKPGEHKPATPAKPADAMADGRLRQGEEGPAVKAMQERLNELGFRDAKGQPLKPDGDFGAATKHALQQAQRAYGLDDDGIAGPKTLEALKKAPPEKGALLSDPANRDNGLYKQAVEGLEKLGPGAFKDRAELERAAGTLTYEARVSGLTSINAVVANANGTGLFAVQGELNDPSARRVHADKEQAVNTPLERSSQQLKQDVPEQPKLAPEQAQERAPKTMTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHK5</accession>
    <name>A0A0S2DHK5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mutator MutT protein</fullName>
            <ecNumber evidence="4">3.6.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mutT</name>
        <name evidence="5" type="ORF">BV903_25460</name>
        <name evidence="4" type="ORF">GLE_2689</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">B25</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000118">
        <property type="protein sequence ID" value="OPD61096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947737.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000118.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58037">
        <property type="protein sequence ID" value="ALN58037"/>
        <property type="gene ID" value="GLE_2689"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61096">
        <property type="protein sequence ID" value="OPD61096"/>
        <property type="gene ID" value="BV903_25460"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2689"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2648"/>
    <dbReference type="OMA" id="PDVWDLP"/>
    <dbReference type="OrthoDB" id="1846332at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="7"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD61096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="137" mass="14853" checksum="583976C71EB5BC7D" modified="2016-02-17" version="1">MSADPTPPIGWVGALLLRDGLVLLGLRALHKRLAPGRWDLPGGHVEPGETPEQALWRELAEETGVGPPADPAAAARIVAEFAFDGVVLRLYAVRDWVGEPRALGDEHQRLQWFAPAQAAALPDLSHPRLGELLRRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DID7</accession>
    <name>A0A0S2DID7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3025</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947989.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3025"/>
    <dbReference type="EnsemblBacteria" id="ALN58373">
        <property type="protein sequence ID" value="ALN58373"/>
        <property type="gene ID" value="GLE_3025"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3025"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2986"/>
    <dbReference type="OMA" id="IAHAYGF"/>
    <dbReference type="OrthoDB" id="1815257at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043767">
        <property type="entry name" value="DUF5713"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18977">
        <property type="entry name" value="DUF5713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="113" mass="12785" checksum="48AA378F6653BF26" modified="2016-02-17" version="1">MTIANTQLQQYDFLADMQADAYFPPFLVAKGQQILIRLCEAIEAERPQSLAALYPLTHAATEEFNRLAEEFERHDSEIETAARENIGEDVEAIAHAYGFDAADIEELIAPRDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIL6</accession>
    <name>A0A0S2DIL6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2889</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58237">
        <property type="protein sequence ID" value="ALN58237"/>
        <property type="gene ID" value="GLE_2889"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2889"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2851"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595245" evidence="1">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="49" mass="5284" checksum="F4806EB9143BE203" modified="2016-02-17" version="1">MSRAKLFLTCCAFAFGLTVSLSAFARPCCSSCDPNQPDSRCWIICSDGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIR4</accession>
    <name>A0A0S2DIR4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_14955</name>
        <name evidence="1" type="ORF">GLE_2990</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947964.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2990"/>
    <dbReference type="EnsemblBacteria" id="ALN58338">
        <property type="protein sequence ID" value="ALN58338"/>
        <property type="gene ID" value="GLE_2990"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2990"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2951"/>
    <dbReference type="OMA" id="GPKDFSQ"/>
    <dbReference type="OrthoDB" id="1519720at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="240" mass="27218" checksum="198619E3E2DC406A" modified="2016-02-17" version="1">MSRTADLSRRMACLLARHQALHDPAREPRNALRWLPELRQWQARRLEASFDRFLRDPRRRPAAQFFLSDVYNDRDFSRRDADIARVLPMMQKLLPGPLLATVADAIELGLLTQAFDLRMSERLHALAPRRRRLDGPLYAQAYRACGLPRLREHQIELIEAVGLGLGKAVRMPGILTLLKLSRGPAKAAGLAELQGFLERGFAAFAQLGDVREFIAEIGSDEREVAQRLFDSDADPFPDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIU4</accession>
    <name>A0A0S2DIU4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9 10">Protein RecA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">Recombinase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 14" type="primary">recA</name>
        <name evidence="15" type="ORF">BV903_09255</name>
        <name evidence="16" type="ORF">FE772_15920</name>
        <name evidence="14" type="ORF">GLE_3203</name>
    </gene>
    <organism evidence="14 17">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">C3</strain>
        </source>
    </reference>
    <reference evidence="15 18" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 18">B25</strain>
        </source>
    </reference>
    <reference evidence="16 19" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 19">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9 11">Belongs to the RecA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000020">
        <property type="protein sequence ID" value="OPD64226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948120.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000020.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3203"/>
    <dbReference type="EnsemblBacteria" id="ALN58549">
        <property type="protein sequence ID" value="ALN58549"/>
        <property type="gene ID" value="GLE_3203"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64226">
        <property type="protein sequence ID" value="OPD64226"/>
        <property type="gene ID" value="BV903_09255"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3203"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3158"/>
    <dbReference type="OMA" id="EGARHMS"/>
    <dbReference type="OrthoDB" id="1080436at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
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        <property type="project" value="InterPro"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00983">
        <property type="entry name" value="recA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00268">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013765">
        <property type="entry name" value="DNA_recomb/repair_RecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020584">
        <property type="entry name" value="DNA_recomb/repair_RecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023400">
        <property type="entry name" value="RecA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45900">
        <property type="entry name" value="PTHR45900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00154">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00142">
        <property type="entry name" value="RECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54752">
        <property type="entry name" value="SSF54752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02012">
        <property type="entry name" value="tigrfam_recA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00321">
        <property type="entry name" value="RECA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
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    </dbReference>
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        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 11" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 9 11" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="8 9 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 9 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 9 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 10" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="RECA_2" evidence="12">
        <location>
            <begin position="35"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="RECA_3" evidence="13">
        <location>
            <begin position="199"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="65"/>
            <end position="72"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN58549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OPD64226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QCW26902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="341" mass="36740" checksum="BB66B1707D165905" modified="2016-02-17" version="1">MDENKKRALAAALGQIEKQFGKGSVMRMGDRAVEAAEVIGTGSLMLDIALGIGGLPKGRVVEIYGPESSGKTTLTLQAIAQCQKNGGTAAFIDAEHALDPIYAAKLGVNIDDLLVSQPDTGEQALEIADMLVRSAAVDMVVVDSVAALTPKAEIEGEMGDQLPGLQARLMSQALRKLTGNIKRSNVLVIFINQLRMKIGVMMPGQSPETTTGGNALKFYASVRLDIRRIGAIKKGDEIIGNQTKIKVVKNKMAPPFKQIVTEILYGEGISREGELIDMGVEAKLVEKSGAWYSCDGERIGQGKENARQYLKENPEMAQRLEANLREKFVPAEASREEAAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIV4</accession>
    <name>A0A0S2DIV4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58432">
        <property type="protein sequence ID" value="ALN58432"/>
        <property type="gene ID" value="GLE_3085"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3085"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3044"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="72" mass="7353" checksum="AF89AD156F3D62D6" modified="2016-02-17" version="1">MAAQGTAAESTKVLGHGRVSRWTAHGGASAWETAATSLPGYGGWDASAGRRRSIGPPLGGRDADRPAPWSAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ29</accession>
    <name>A0A0S2DJ29_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Patatin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_15325</name>
        <name evidence="5" type="ORF">GLE_3066</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948019.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3066"/>
    <dbReference type="EnsemblBacteria" id="ALN58413">
        <property type="protein sequence ID" value="ALN58413"/>
        <property type="gene ID" value="GLE_3066"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3066"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3026"/>
    <dbReference type="OMA" id="WANNPVM"/>
    <dbReference type="OrthoDB" id="373926at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="4">
        <location>
            <begin position="7"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="2">
        <location>
            <begin position="11"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="72"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="210"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW26809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="343" mass="37028" checksum="65CF0C4C1324093E" modified="2016-02-17" version="1">MKMRRILCLDGGGIRGLVSCHWLAGVEQALAQAGKPPAGKARAENARDVPAPSAKTTGDKHGLLDRFDLLAGSSTGALVACGLAAGFSPDALAQLYRDQRHTIFPNLAGRLWSRANRLVSDGFSAPRYDGSGIEQVLRKVFGKTTLGQLKAPVLVTSYDTISRTPVIFKSFDPKHRDLPVWEVCRASTAAPTYFPAHPMKVEGKHCALIDGGVVANNPTACAIAEALRKDAKVDNSRDLVVLSVGTGERTRSISLESARTWGALEWAVPIIDVLFDGNTDSVDYIARQLVGDGYYRMQAELLVGLDDLDDTSETNVLALETLAKEYLTRPATKKMLAQLVKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ32</accession>
    <name>A0A0S2DJ32_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rluC</name>
        <name evidence="5" type="ORF">GLE_2948</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for synthesis of pseudouridine from uracil.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2948"/>
    <dbReference type="EnsemblBacteria" id="ALN58296">
        <property type="protein sequence ID" value="ALN58296"/>
        <property type="gene ID" value="GLE_2948"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2948"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2910"/>
    <dbReference type="OMA" id="PKTHVYR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="4">
        <location>
            <begin position="10"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR606225-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="305" mass="33653" checksum="CB29CC3763106BA3" modified="2016-02-17" version="1">MRVPDDREGQRLDNFLLGQLKGAPRSLIYKLVRSGQVRVNGGRAKAERKLEAGDEVRIPPVRLTEAGDKPAPPKGFLEAMERAIVFEDARLLALSKPSGVASHGGSGISFGAIETLRALRPNQTLELVHRLDRDTSGLLIVAKKRSALTEMQALMREEGGIAKRYLALLTGRMPDGVMTVDAPLHIGLRQGGERHVQVHRDGKASLSHFKVLERRGGQSYCEVRIETGRTHQIRVHSQHIGHPVAGDDKYGEAEVNKKLRDQFGLRRLFLHASTLEFALDGGRERYSLNAPLAPELIEVLDRLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ45</accession>
    <name>A0A0S2DJ45_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutathione peroxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hyr1</name>
        <name evidence="8" type="ORF">D9T17_17410</name>
        <name evidence="7" type="ORF">FE772_15385</name>
        <name evidence="6" type="ORF">GLE_3082</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">OH11</strain>
        </source>
    </reference>
    <reference evidence="7 11" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 11">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glutathione peroxidase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000043">
        <property type="protein sequence ID" value="ROU05698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948029.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3082"/>
    <dbReference type="EnsemblBacteria" id="ALN58429">
        <property type="protein sequence ID" value="ALN58429"/>
        <property type="gene ID" value="GLE_3082"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3082"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3041"/>
    <dbReference type="OMA" id="KVVRFWR"/>
    <dbReference type="OrthoDB" id="1635499at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00340">
        <property type="entry name" value="GSH_Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000889">
        <property type="entry name" value="Glutathione_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029759">
        <property type="entry name" value="GPX_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592">
        <property type="entry name" value="PTHR11592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00255">
        <property type="entry name" value="GSHPx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000303">
        <property type="entry name" value="Glutathion_perox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01011">
        <property type="entry name" value="GLUTPROXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00460">
        <property type="entry name" value="GLUTATHIONE_PEROXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51355">
        <property type="entry name" value="GLUTATHIONE_PEROXID_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 5 6" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="4">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000303-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW26818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROU05698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="161" mass="18184" checksum="D04D81546A61725E" modified="2016-02-17" version="1">MTIAYDFSAVDIDGRDQSLDRYRGKVLLIVNVASKCGFTPQYTGLEKLQRDYQSRGFDVLGFPCDQFGHQEPGDEAEIKEFCSLTYDVSFPMYSKVDVNGDKAHPLWKWLKDEKGGFLGIDAIKWNFTKFLVGRDGRVLKRYAPTDKPESIAADIEKALAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJH0</accession>
    <name>A0A0S2DJH0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Arginase</fullName>
            <ecNumber evidence="3 10">3.5.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rocF</name>
        <name evidence="12" type="ORF">FE772_15955</name>
        <name evidence="11" type="ORF">GLE_3211</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>H2O + L-arginine = L-ornithine + urea</text>
            <dbReference type="Rhea" id="RHEA:20569"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="EC" id="3.5.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="10">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the arginase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.3.1" evidence="3 10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948126.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3211"/>
    <dbReference type="EnsemblBacteria" id="ALN58557">
        <property type="protein sequence ID" value="ALN58557"/>
        <property type="gene ID" value="GLE_3211"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3211"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3166"/>
    <dbReference type="OMA" id="DTPFQIV"/>
    <dbReference type="OrthoDB" id="1598732at2"/>
    <dbReference type="UniPathway" id="UPA00158">
        <property type="reaction ID" value="UER00270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004053">
        <property type="term" value="F:arginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006525">
        <property type="term" value="P:arginine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000050">
        <property type="term" value="P:urea cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd09989">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014033">
        <property type="entry name" value="Arginase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020855">
        <property type="entry name" value="Ureohydrolase_Mn_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43782">
        <property type="entry name" value="PTHR43782"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036979">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00116">
        <property type="entry name" value="ARGINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01229">
        <property type="entry name" value="rocF_arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01053">
        <property type="entry name" value="ARGINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0056">Arginine metabolism</keyword>
    <keyword evidence="7 9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN58557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW26907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="313" mass="33114" checksum="FBD5144A0F2BFD9E" modified="2016-02-17" version="1">MSSPTASPVSALPVSLIGAPTDVGAGDRGARLGPEALRIAGLREALHGLGLDVADRGNLDGPPNPWTGPVDGYRHLDEVIAWNRQVMNAVSAELGLGRMPILLGGDHCLGLGSITAVAQHCRAHGKKLRVLWLDAHADFNTNDITPSGNLHGMPVACLIGLGPRELTHLGGEAPAMQAGQMRQIGTRSVDAGEKQLIRRHGLPVYDMRRIGDLGIKRVMEDALADLDEDTHLHVSFDVDFLDPSIAPGVGTGVAGGPNYREAQLAMEMIAESGRMGSLDIVELNPILDRDNATALIAIDLVESLFGKSTLVRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJI6</accession>
    <name>A0A0S2DJI6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Potassium transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="10">Transporter, monovalent cation:proton antiporter-2 (CPA2) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BV903_20550</name>
        <name evidence="12" type="ORF">FE772_16535</name>
        <name evidence="10" type="ORF">GLE_3345</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">C3</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000062">
        <property type="protein sequence ID" value="OPD62073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948228.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000062.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3345"/>
    <dbReference type="EnsemblBacteria" id="ALN58691">
        <property type="protein sequence ID" value="ALN58691"/>
        <property type="gene ID" value="GLE_3345"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62073">
        <property type="protein sequence ID" value="OPD62073"/>
        <property type="gene ID" value="BV903_20550"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3345"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3295"/>
    <dbReference type="OMA" id="MMMLYMG"/>
    <dbReference type="OrthoDB" id="941006at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004771">
        <property type="entry name" value="K/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00932">
        <property type="entry name" value="2a37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0050">Antiport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="303"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="338"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="9">
        <location>
            <begin position="409"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="587"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN58691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OPD62073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW27009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="609" mass="64055" checksum="27484F7804281D21" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJS5</accession>
    <name>A0A0S2DJS5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3543</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3543"/>
    <dbReference type="EnsemblBacteria" id="ALN58887">
        <property type="protein sequence ID" value="ALN58887"/>
        <property type="gene ID" value="GLE_3543"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3543"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3487"/>
    <dbReference type="OMA" id="PRMPCFI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045500">
        <property type="entry name" value="DUF6491"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20101">
        <property type="entry name" value="DUF6491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="190" mass="20932" checksum="244BB1AD36D22A80" modified="2016-02-17" version="1">MPAGDAPAARAKRMMRAYSHRRRCRHKETPMKRPTVAIPRGRAARLLAACLAVAALAGCASAGPKLDDAQRLALYRQHAGAPVDSFQYFGRIDGWTPLGDSALGLWTKPSQAYLLELRGSCQGLDFAQAITVTNQMGRVHQRFDKVVVLDRQSIKMPCFIDRILPLDVKALKQAQHDLRSAGTMPEESKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJZ7</accession>
    <name>A0A0S2DJZ7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Hemolysin</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="14">HlyC/CorC family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BV903_21525</name>
        <name evidence="14" type="ORF">FE772_17240</name>
        <name evidence="12" type="ORF">GLE_3503</name>
    </gene>
    <organism evidence="12 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">C3</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">B25</strain>
        </source>
    </reference>
    <reference evidence="14 17" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000071">
        <property type="protein sequence ID" value="OPD61861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948339.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000071.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3503"/>
    <dbReference type="EnsemblBacteria" id="ALN58848">
        <property type="protein sequence ID" value="ALN58848"/>
        <property type="gene ID" value="GLE_3503"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61861">
        <property type="protein sequence ID" value="OPD61861"/>
        <property type="gene ID" value="BV903_21525"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3503"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3447"/>
    <dbReference type="OMA" id="EHTMVRN"/>
    <dbReference type="OrthoDB" id="1155802at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="11">
        <location>
            <begin position="1"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="217"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="281"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN58848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OPD61861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW27120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="443" mass="48106" checksum="052AEAB6942A6EED" modified="2016-02-17" version="1">MLELLIVVALIVLNAFFAMSEMALMTSRKLRLKQMAETSKGARTALALAEQPDNLLSSVQIGITGIGVLTGYFGGESIGLVIAGWLSHVLTGDFAQYARPIGIGTAMALITASQVIFGELIPKRLALTNPERIASTVAVVLYTITRVASPVVRALGAINRFVLRLLGIKDDARSEISEEEIRLLVSESHEQGVIDADERKMVNRVLSLGDRTADSLMTPRTRIAWLDASASREENLAIMRESPFSRFPVYRGSDQDVLGVLEAKALLADLVQGRVPDLFGQLKEALFVSESTHALKLLEIFREEQQSVALVVDEYGDVTGLITVNDLLGAVIGRVQNADSDDQPGPVVQREDGSYLVDGALPVEELREVVGGRLPNEDEHDFNTVAGMVIAHFGRIPHVGEHFAWAGWRIEVIDLDGPRIDKLLLQPQQAKPAESGDDDATSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKN1</accession>
    <name>A0A0S2DKN1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">30S ribosomal protein S4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">rpsD</name>
        <name evidence="12" type="ORF">BV903_22920</name>
        <name evidence="14" type="ORF">D9T17_09545</name>
        <name evidence="13" type="ORF">FE772_18535</name>
        <name evidence="11" type="ORF">GLE_3767</name>
    </gene>
    <organism evidence="11 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 15">C3</strain>
        </source>
    </reference>
    <reference evidence="12 16" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 16">B25</strain>
        </source>
    </reference>
    <reference evidence="14 17" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">OH11</strain>
        </source>
    </reference>
    <reference evidence="13 18" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 18">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="7">With S5 and S12 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000077">
        <property type="protein sequence ID" value="OPD61594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000023">
        <property type="protein sequence ID" value="ROU07204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948534.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3767"/>
    <dbReference type="EnsemblBacteria" id="ALN59111">
        <property type="protein sequence ID" value="ALN59111"/>
        <property type="gene ID" value="GLE_3767"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61594">
        <property type="protein sequence ID" value="OPD61594"/>
        <property type="gene ID" value="BV903_22920"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3767"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3711"/>
    <dbReference type="OMA" id="NVVFRMG"/>
    <dbReference type="OrthoDB" id="1211060at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01306_B">
        <property type="entry name" value="Ribosomal_S4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_S4/S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001912">
        <property type="entry name" value="Ribosomal_S4/S9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005709">
        <property type="entry name" value="Ribosomal_S4_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018079">
        <property type="entry name" value="Ribosomal_S4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="PTHR11831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF4">
        <property type="entry name" value="PTHR11831:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00163">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01390">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01017">
        <property type="entry name" value="rpsD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00632">
        <property type="entry name" value="RIBOSOMAL_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_S4" evidence="10">
        <location>
            <begin position="3"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="S4" evidence="9">
        <location>
            <begin position="98"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN59111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OPD61594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW27339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROU07204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="209" mass="23418" checksum="8216AED73F58D513" modified="2016-02-17" version="1">MARYIGPTCKLARREGADLSLKSSARALDSKCKLEQKPGQHGPTARKGKLSDYATQLREKQKVKRIYGLLERQFRNYYKKASTKKGNTGENLLQFLETRLDNVVYRMGFAVTRPAARQLVSHRGVTVNGKSVNLPSYQVKAGDIIALSERAQKQLRVQESLTVSSQMDLSPSWVEVDSKKFSGVFKAIPDRADLPADINEALIVELYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKP6</accession>
    <name>A0A0S2DKP6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_18915</name>
        <name evidence="3" type="ORF">GLE_3846</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948594.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59189">
        <property type="protein sequence ID" value="ALN59189"/>
        <property type="gene ID" value="GLE_3846"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3846"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3786"/>
    <dbReference type="OrthoDB" id="1834394at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726733" evidence="2">
        <location>
            <begin position="27"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="185" mass="19394" checksum="3AA0A3AD8FF35920" modified="2016-02-17" version="1">MSPLSRRFVPSVIAVSLCLAVGACMASGSASSDAAASPTPESAPNPPSEASVDAVPTPEPPPMPSDRAADPRKPKAEVGEPAGAGPFGQFIVKYRDDSQPLKQLGAVQPRLDRTAGQLGKRRLKLTWKHRMGINADVFSVAPALDRAEAVALMQAFAADPDVQFIEPDNHISLGPIIRSPAPVDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKQ5</accession>
    <name>A0A0S2DKQ5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Transcription termination/antitermination protein NusG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">nusG</name>
        <name evidence="9" type="ORF">GLE_3802</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Participates in transcription elongation, termination and antitermination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the NusG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3802"/>
    <dbReference type="EnsemblBacteria" id="ALN59146">
        <property type="protein sequence ID" value="ALN59146"/>
        <property type="gene ID" value="GLE_3802"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3802"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3746"/>
    <dbReference type="OMA" id="DGPFNGF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006354">
        <property type="term" value="P:DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00948">
        <property type="entry name" value="NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006645">
        <property type="entry name" value="NGN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036735">
        <property type="entry name" value="NGN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043425">
        <property type="entry name" value="NusG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001062">
        <property type="entry name" value="Transcrpt_antiterm_NusG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015869">
        <property type="entry name" value="Transcrpt_antiterm_NusG_bac_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30265">
        <property type="entry name" value="PTHR30265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30265:SF2">
        <property type="entry name" value="PTHR30265:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02357">
        <property type="entry name" value="NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00338">
        <property type="entry name" value="NUSGTNSCPFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00738">
        <property type="entry name" value="NGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82679">
        <property type="entry name" value="SSF82679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00922">
        <property type="entry name" value="nusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01014">
        <property type="entry name" value="NUSG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 5 6" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="3 5 6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 5 6" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="NGN" evidence="7">
        <location>
            <begin position="6"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="8">
        <location>
            <begin position="136"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN59146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="191" mass="21948" checksum="4B5B5EF7C0D4218F" modified="2016-02-17" version="1">MNTQENKRWYVVHAYSGFEKSVAQALRDRIVRFEMTDRFGEVLVPTEEVVEMRSGQKRRSERKFFPGYVLVQIATHDEAGIPRIDSESWHLIKETPKVMGFIGGTADRPLPIQDVEADRILQRVQEGVEKPRPKVLFEPGEMVRVIDGPFVDFNGVVEEINYEKSRLRVAVLIFGRSTPVELEFGQVEKAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKR5</accession>
    <name>A0A0S2DKR5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_17200</name>
        <name evidence="2" type="ORF">GLE_3495</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948332.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58840">
        <property type="protein sequence ID" value="ALN58840"/>
        <property type="gene ID" value="GLE_3495"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3495"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3440"/>
    <dbReference type="OMA" id="YTIADEP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="159" mass="16932" checksum="F3641F10F6B8A575" modified="2016-02-17" version="1">MAERALYRLPDEPLPSGLSRYATDPLWPLLTLMLAGGGFGLAWFAFNSAALGSPTRMREWGCVALSLLGAPALVIAVTVAVGAGWLTPAAAQYALLSVLLLKVAVAYALYLMQQRTFDIWEHYGGEPRNGMPLTILLAVVGRGALDLSALPPLLRAALQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKU1</accession>
    <name>A0A0S2DKU1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948580.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59168">
        <property type="protein sequence ID" value="ALN59168"/>
        <property type="gene ID" value="GLE_3825"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3825"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3767"/>
    <dbReference type="OMA" id="AFIPNEM"/>
    <dbReference type="OrthoDB" id="2029956at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594906" evidence="1">
        <location>
            <begin position="30"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="146" mass="14579" checksum="1B69695807251E57" modified="2016-02-17" version="1">MPRNAERLLLLAAACVAAIALPAGMPARAAVQSDAASRQSATSLDASVEVPVAAAHALSQGAKFSVTAIQASGNAVAVTVSAVGAGTSLVVKLSAEQARDLGLSVGASVAITAVAAGWLISDAAGHVFCFVPDERARRHVHSRKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKY1</accession>
    <name>A0A0S2DKY1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3981</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59323">
        <property type="protein sequence ID" value="ALN59323"/>
        <property type="gene ID" value="GLE_3981"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3981"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3919"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="37" mass="4271" checksum="D4F8A4DD88580049" modified="2016-02-17" version="1">MNRAVAEQLVWEGGCGRAFRPDAFRSGRRDLKKQHRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKY8</accession>
    <name>A0A0S2DKY8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">3-oxoacyl-[acyl-carrier-protein (ACP)] synthase III</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Ketoacyl-ACP synthase III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_17795</name>
        <name evidence="5" type="ORF">GLE_3615</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58959.1"/>
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        <source>
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    <evidence type="ECO:0000259" key="3">
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            <dbReference type="Pfam" id="PF08545"/>
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    </evidence>
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            <dbReference type="EMBL" id="ALN58959.1"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW27206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="361" mass="37991" checksum="BC40A2FF9F987BF0" modified="2016-02-17" version="1">MDIRTTQHSPPSGSAADTAGARRGHGATADLDWRVRIAGLGRYLPRRRVDSAQIEDRVGLPRGWALENSGVAFRHWAEPETERASWMGAQAALQACERAGIEPGSVDLIVNASGSAERAIPDGGPLLQRELGLGRSGIASLSVHATCLSFVAALELAAERIHHGRIERALVVSSEIASVGLDFANPEVCTLFGDGAAAAVLERAAQDSPSRIHRIAWRTMGEGVEITTLRGGGSWRPPLGPNTVPADALFSMQGQAALRSGIRLVPHVMRRLGLDDMAARAALRWVAPHQASRAALDVIEQIGFAGAAMVRTLEDTGNCIAASIPLALEQGVREGQIRRGDTGILLGTGAGLSGVGLTLTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="49" mass="5553" checksum="ED6D81378F0841A6" modified="2016-02-17" version="1">MLSRTEDIKVGPVKVHTKFTLDFSDGFHVVIEGHVETFINLDFGPIRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLM8</accession>
    <name>A0A0S2DLM8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">LamG domain-containing protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="6" type="ORF">FE772_19960</name>
        <name evidence="5" type="ORF">GLE_4066</name>
    </gene>
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        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    <dbReference type="EnsemblBacteria" id="ALN59408">
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        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
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        <location>
            <begin position="23"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="LamGL" evidence="4">
        <location>
            <begin position="92"/>
            <end position="234"/>
        </location>
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        <location>
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            <end position="371"/>
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        <location>
            <begin position="348"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59408.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW27578.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="398" mass="42358" checksum="BB8303BCA4C69C76" modified="2016-02-17" version="1">MNRSSWFLALAVALAPMLAAQAAPPRVSNGLVGEWHLDLSGTSAPDTSGYGRNGSVIGGAASSWGWLGSAADLSGGKYIEVPNSANLNVGTGSFTVAAWVRLAAPGSSGVKTLIENRGDGSGRGYSFGIDQGRNVLLQLNDGSTWGNYVSDGSVSLAANRWHHIAAVVNRSSAPYTISFYVDGRRATGQPTPMAGNLDNTTRPFMIGGHISSPTYRFNDRADEVLVYNRALPADASGGLGDIMFPGRTNYQPTFWNDGGTRQRYNNCYNYANGRATNTFAQPGRAASAQYSSLSCAAVRAAAERDGLEPVADTAINAASYKNIAALVVAPGYDYHWYRRDANGKWTHKPGQTAATNRDNSGNEIGDPRTANRGPYSDFCGFYRVWSDSIEGSGHEQIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLT8</accession>
    <name>A0A0S2DLT8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">30S ribosomal protein S11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">rpsK</name>
        <name evidence="11" type="ORF">BV903_22925</name>
        <name evidence="13" type="ORF">D9T17_09540</name>
        <name evidence="12" type="ORF">FE772_18540</name>
        <name evidence="9" type="ORF">GLE_3768</name>
        <name evidence="10" type="ORF">LEN_1375</name>
        <name evidence="14" type="ORF">SAMN05421681_11025</name>
    </gene>
    <organism evidence="9 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 15">C3</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="journal article" date="2016" name="DNA Res." volume="0" first="0" last="0">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer, Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">M497-1</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="3">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">ATCC 29487</strain>
        </source>
    </reference>
    <reference evidence="10 18" key="4">
        <citation type="journal article" date="2017" name="DNA Res." volume="24" first="169" last="177">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
            <dbReference type="PubMed" id="28065880"/>
            <dbReference type="DOI" id=".1093/dnares/dsw055"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 18">M497-1</strain>
        </source>
    </reference>
    <reference evidence="11 17" key="5">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 17">B25</strain>
        </source>
    </reference>
    <reference evidence="13 19" key="6">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 19">OH11</strain>
        </source>
    </reference>
    <reference evidence="12 20" key="7">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 20">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="BAV96862.1"/>
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    </dbReference>
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        <property type="protein sequence ID" value="OPD61595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW27340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000023">
        <property type="protein sequence ID" value="ROU07203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNOG01000010">
        <property type="protein sequence ID" value="SDY03596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948535.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3768"/>
    <dbReference type="EnsemblBacteria" id="ALN59112">
        <property type="protein sequence ID" value="ALN59112"/>
        <property type="gene ID" value="GLE_3768"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAV96862">
        <property type="protein sequence ID" value="BAV96862"/>
        <property type="gene ID" value="LEN_1375"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61595">
        <property type="protein sequence ID" value="OPD61595"/>
        <property type="gene ID" value="BV903_22925"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY03596">
        <property type="protein sequence ID" value="SDY03596"/>
        <property type="gene ID" value="SAMN05421681_11025"/>
    </dbReference>
    <dbReference type="KEGG" id="lem:LEN_1375"/>
    <dbReference type="KEGG" id="lez:GLE_3768"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3712"/>
    <dbReference type="OMA" id="KWGVAHI"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000183696">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000218824">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01310">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019981">
        <property type="entry name" value="Ribosomal_S11_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018102">
        <property type="entry name" value="Ribosomal_S11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_S11_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11759">
        <property type="entry name" value="PTHR11759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00411">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002131">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03632">
        <property type="entry name" value="uS11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00054">
        <property type="entry name" value="RIBOSOMAL_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN59112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAV96862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OPD61595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW27340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROU07203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="SDY03596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000183696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000218824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="130" mass="13854" checksum="F98DD4D86AB9DF88" modified="2016-02-17" version="1">MAKPAAVKTKKKIKRVVTDGIAHVHASFNNTIITITDRQGNALSWATSGGAGFRGSRKSTPFAAQVAAEKAGRAALDYGVKSLEVRIKGPGPGRESAVRSLNNVGYKIINIIDVTPIPHNGCRPPKKRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLY7</accession>
    <name>A0A0S2DLY7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Asparaginase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BV903_23475</name>
        <name evidence="6" type="ORF">FE772_18875</name>
        <name evidence="4" type="ORF">GLE_3833</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">C3</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000082">
        <property type="protein sequence ID" value="OPD61489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948587.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000082.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3833"/>
    <dbReference type="EnsemblBacteria" id="ALN59176">
        <property type="protein sequence ID" value="ALN59176"/>
        <property type="gene ID" value="GLE_3833"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61489">
        <property type="protein sequence ID" value="OPD61489"/>
        <property type="gene ID" value="BV903_23475"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3833"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3775"/>
    <dbReference type="OMA" id="PGVYVAM"/>
    <dbReference type="OrthoDB" id="1659551at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004067">
        <property type="term" value="F:asparaginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036152">
        <property type="entry name" value="Asp/glu_Ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006034">
        <property type="entry name" value="Asparaginase/glutaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027474">
        <property type="entry name" value="L-asparaginase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037152">
        <property type="entry name" value="L-asparaginase_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00710">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001220">
        <property type="entry name" value="L-ASNase_gatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00139">
        <property type="entry name" value="ASNGLNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53774">
        <property type="entry name" value="SSF53774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51732">
        <property type="entry name" value="ASN_GLN_ASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Asparaginase" evidence="3">
        <location>
            <begin position="3"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="83"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="active site" description="O-isoaspartyl threonine intermediate" evidence="1">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR001220-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001220-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD61489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW27396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="161" mass="17589" checksum="1581B3FFEE9590E6" modified="2016-02-17" version="1">MDKLCIVTTGGTIDKIYFDDKSDYQIGEPQIGHILEELGVGFRYNVIPIIRKDSLHISAQDRELIRATIAAQDARHVLVTHGTDSMVETAKVLATIADKTIVLTGALNPARFRGSDAEFNIGTAVGAVQSLPPGVYIAMNGRIWDPAKVRKNVEANRFEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM39</accession>
    <name>A0A0S2DM39_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">Signal peptidase I</fullName>
            <ecNumber evidence="3 7">3.4.21.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">lepB</name>
        <name evidence="11" type="ORF">BV903_11995</name>
        <name evidence="12" type="ORF">FE772_21610</name>
        <name evidence="10" type="ORF">GLE_4425</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">C3</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.</text>
            <dbReference type="EC" id="3.4.21.89"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the peptidase S26 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.89" evidence="3 7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000028">
        <property type="protein sequence ID" value="OPD63765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949044.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000028.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4425"/>
    <dbReference type="EnsemblBacteria" id="ALN59766">
        <property type="protein sequence ID" value="ALN59766"/>
        <property type="gene ID" value="GLE_4425"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63765">
        <property type="protein sequence ID" value="OPD63765"/>
        <property type="gene ID" value="BV903_11995"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4425"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4363"/>
    <dbReference type="OMA" id="SDSRFWG"/>
    <dbReference type="OrthoDB" id="1741894at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019758">
        <property type="entry name" value="Pept_S26A_signal_pept_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019757">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Lys-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019756">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43390">
        <property type="entry name" value="PTHR43390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02227">
        <property type="entry name" value="sigpep_I_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00501">
        <property type="entry name" value="SPASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00760">
        <property type="entry name" value="SPASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00761">
        <property type="entry name" value="SPASE_I_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S26" evidence="9">
        <location>
            <begin position="47"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR600223-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OPD63765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW27859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="261" mass="29282" checksum="321810A018DFFF23" modified="2016-02-17" version="1">MRWFEIALVSLTAFTGLVWLLDKHWLARRRAARAGLLDEGEEPWVVDYSKAFFPVLLVVLVLRSFVAEPFRIPSNSMMPTLLTGDFVLTNKFVYGLRLPISNTKVLPLGAPERGDVVVFHSVQRADVNLIKRVVGLPGDRVEYRDGRLTINGAAVAYQPVGVYTGHGSGAEATGAQELSETLGRHVHRVLLRRDLPQPLLAEGEWTVPAGQYFVMGDNRDNSEDSRYWGFLPERNLVGRAFLVWLNFDDGFDFERIGTSIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM94</accession>
    <name>A0A0S2DM94_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_03330</name>
        <name evidence="3" type="ORF">FE772_21835</name>
        <name evidence="1" type="ORF">GLE_4473</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000006">
        <property type="protein sequence ID" value="OPD65407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59814">
        <property type="protein sequence ID" value="ALN59814"/>
        <property type="gene ID" value="GLE_4473"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65407">
        <property type="protein sequence ID" value="OPD65407"/>
        <property type="gene ID" value="BV903_03330"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4473"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4410"/>
    <dbReference type="OMA" id="CFERDDS"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD65407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="114" mass="12977" checksum="2A51D55252B58275" modified="2016-02-17" version="1">MSQSDDAQHYFTQQVAHLLQGRDSAVVDAAQLTDFDWQQLCFEREDQLELKFSGAGGEKVFRFGYEDYFVAEPYVARSPAERCIGRQDKLVLKKKYPGYKDTVEFQLADGAATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMA2</accession>
    <name>A0A0S2DMA2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4381"/>
    <dbReference type="EnsemblBacteria" id="ALN59722">
        <property type="protein sequence ID" value="ALN59722"/>
        <property type="gene ID" value="GLE_4381"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4381"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4320"/>
    <dbReference type="OMA" id="MHVHVWD"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="393"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="528" mass="56642" checksum="7C55FE3284B34A71" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMC9</accession>
    <name>A0A0S2DMC9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lipoprotein, LppC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4143</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4143"/>
    <dbReference type="EnsemblBacteria" id="ALN59485">
        <property type="protein sequence ID" value="ALN59485"/>
        <property type="gene ID" value="GLE_4143"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4143"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4085"/>
    <dbReference type="OMA" id="WQWITSI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007443">
        <property type="entry name" value="LpoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38038">
        <property type="entry name" value="PTHR38038"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04348">
        <property type="entry name" value="LppC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="450" mass="47007" checksum="15ECFB343A5F4911" modified="2016-02-17" version="1">MFCALAATAVLGGCASVETRPVATVAASNPIVAQAQHLARNHASLSGAERSENERQIERLLGQLDDATLSREANALIEGDPLYNFVGRALMKRGLPLPRPFDRTSDWSFHSAQRPPAEADGYRPPVKLAVLLPSTGPAAAAAAAVRDGLLAAYYGESRRRPEIHFYDTAGTPAGTLSAYDKAAAEGNDFVIGPLGRDEVSALFGKNALPVPVLALNRGNTPPPSGNVSFSLTPEDEGTAAADYLVERKAKRVLVIAGDDDSQRRAVAAFKERLAGRGAAVTDAIGEGTADLTPFVTKEGGVDAVFLAVKGSVGRTLVPKMALSGLADKPRAATSQLLLGTGKPEQDRVLDGIAFPSESWISGGIRGLPPAVGTAQQLPTARGPAARLFAFGYDAWQLSAYLERLAGRSDAYVAGATGVLRIDGFGNVLRTPAWSTFSSGVAVPLADASRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMF4</accession>
    <name>A0A0S2DMF4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Glutathione S-transferase, N-domain</fullName>
            <ecNumber evidence="2">2.5.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_21430</name>
        <name evidence="2" type="ORF">GLE_4387</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.5.1.18" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949012.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4387"/>
    <dbReference type="EnsemblBacteria" id="ALN59728">
        <property type="protein sequence ID" value="ALN59728"/>
        <property type="gene ID" value="GLE_4387"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4387"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4326"/>
    <dbReference type="OMA" id="VDIGTIA"/>
    <dbReference type="OrthoDB" id="1819702at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034343">
        <property type="entry name" value="YibF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42673:SF12">
        <property type="entry name" value="PTHR42673:SF12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="205" mass="23022" checksum="5254B41D3A57627B" modified="2016-02-17" version="1">MRLLYQTHSPFARKALVFALEAGLGECIEVVHHETSPTLRNEAVYAQNPLGKVPVLLRPGLAPIFDSDVICAYLDALHAGAPLIPADGEARWHALRLQAVAQGLADAGIKVRWETVRRPEALRYEVLREGYTQKLVESYDWLERELDTDSPLHVGHIAVATALSWLEFRELPDFRIGRPRLAAWQDAFERRASMRATPLSGQTHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMK7</accession>
    <name>A0A0S2DMK7_LYSEN</name>
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        <submittedName>
            <fullName evidence="4">DUF1801 domain-containing protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="4" type="ORF">FE772_21925</name>
        <name evidence="2" type="ORF">GLE_4490</name>
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        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ALN59831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD65349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4490"/>
    <dbReference type="EnsemblBacteria" id="ALN59831">
        <property type="protein sequence ID" value="ALN59831"/>
        <property type="gene ID" value="GLE_4490"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65349">
        <property type="protein sequence ID" value="OPD65349"/>
        <property type="gene ID" value="BV903_03415"/>
    </dbReference>
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    <dbReference type="PATRIC" id="fig|69.6.peg.4427"/>
    <dbReference type="OMA" id="GVPVWEH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR014922">
        <property type="entry name" value="DUF1801"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08818">
        <property type="entry name" value="DUF1801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1801" evidence="1">
        <location>
            <begin position="33"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD65349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="135" mass="14682" checksum="B5255E3B9F241271" modified="2016-02-17" version="1">MSKNTGADAAPTDVAASRLIDERIQELADWRGETLAQVRKLIREADPQIVEEWKWRGVPVWSRGGIVCTGETYKSAVKLTFAKGASLPDPKGLFNASLDGNTRRAIDIHEGDKIDGKALQALVRAAIALNASKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DML4</accession>
    <name>A0A0S2DML4_LYSEN</name>
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        <submittedName>
            <fullName evidence="6">ABC transporter, ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">ABC-F family ATP-binding cassette domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FE772_19990</name>
        <name evidence="6" type="ORF">GLE_4074</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW27584.1"/>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4074"/>
    <dbReference type="EnsemblBacteria" id="ALN59416">
        <property type="protein sequence ID" value="ALN59416"/>
        <property type="gene ID" value="GLE_4074"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4074"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4016"/>
    <dbReference type="OMA" id="CTHIADI"/>
    <dbReference type="OrthoDB" id="1112046at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
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        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
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        <property type="match status" value="2"/>
    </dbReference>
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    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="2"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="313"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="558"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
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        <location>
            <begin position="345"/>
            <end position="352"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW27584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="620" mass="67820" checksum="1920C91045C8FD71" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMV7</accession>
    <name>A0A0S2DMV7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rod shape-determining protein MreD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">mreD</name>
        <name evidence="11" type="ORF">BV903_03490</name>
        <name evidence="10" type="ORF">GLE_4511</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">B25</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the MreD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000006">
        <property type="protein sequence ID" value="OPD65362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949110.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4511"/>
    <dbReference type="EnsemblBacteria" id="ALN59852">
        <property type="protein sequence ID" value="ALN59852"/>
        <property type="gene ID" value="GLE_4511"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65362">
        <property type="protein sequence ID" value="OPD65362"/>
        <property type="gene ID" value="BV903_03490"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4511"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4447"/>
    <dbReference type="OMA" id="YWAMALP"/>
    <dbReference type="OrthoDB" id="1888959at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007227">
        <property type="entry name" value="Cell_shape_determining_MreD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026034">
        <property type="entry name" value="MreD_proteobac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37484">
        <property type="entry name" value="PTHR37484"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04093">
        <property type="entry name" value="MreD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018472">
        <property type="entry name" value="MreD_proteobac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03426">
        <property type="entry name" value="shape_MreD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR018472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OPD65362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="161" mass="18164" checksum="8C53277028D97176" modified="2016-02-17" version="1">MTRARHHWVLPVSLIAALALSLLPMPQVLAPLRPFWLGLVLAYWVIEDPERVGLGFAFIVGLCGDLVSDGLLGEQALRLVVMAFILQRFRARLRFFPLSQQALAIGGLMLNDRIVTAVVHMVLREPSLPTTYWFAPLVGMALWPVIFLLLDALRLGTWRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN26</accession>
    <name>A0A0S2DN26_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Flagellar M-ring protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">fliF</name>
        <name evidence="16" type="ORF">GLE_4637</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 12">The M ring may be actively involved in energy transduction.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The M ring is integral to the inner membrane of the cell and may be connected to the flagellar rod via the S ring. The S (supramembrane ring) lies just distal to the M ring. The L and P rings lie in the outer membrane and the periplasmic space, respectively.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 12">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the FliF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949201.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4637"/>
    <dbReference type="EnsemblBacteria" id="ALN59978">
        <property type="protein sequence ID" value="ALN59978"/>
        <property type="gene ID" value="GLE_4637"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4637"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4573"/>
    <dbReference type="OMA" id="ERAQHAN"/>
    <dbReference type="OrthoDB" id="167675at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009431">
        <property type="term" value="C:bacterial-type flagellum basal body, MS ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013556">
        <property type="entry name" value="Flag_M-ring_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000067">
        <property type="entry name" value="FlgMring_FliF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006182">
        <property type="entry name" value="FliF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043427">
        <property type="entry name" value="YscJ/FliF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30046">
        <property type="entry name" value="PTHR30046"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30046:SF0">
        <property type="entry name" value="PTHR30046:SF0"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01514">
        <property type="entry name" value="YscJ_FliF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08345">
        <property type="entry name" value="YscJ_FliF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004862">
        <property type="entry name" value="FliF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01009">
        <property type="entry name" value="FLGMRINGFLIF"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00206">
        <property type="entry name" value="fliF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="16" id="KW-0966">Cell projection</keyword>
    <keyword evidence="16" id="KW-0969">Cilium</keyword>
    <keyword evidence="16" id="KW-0282">Flagellum</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="YscJ_FliF" evidence="14">
        <location>
            <begin position="48"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="YscJ_FliF_C" evidence="15">
        <location>
            <begin position="251"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR004862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ALN59978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="485" mass="51278" checksum="160628962737B994" modified="2016-02-17" version="1">MDTATHTPNAGGWLARLQADPRRRQIAVAVALSLLIFALLLGGYLMLRPNYIVLFRGLKPLDAAAVVKELEKEKIPYRYDEAANAILVPEGESKATRIKLGSADLRLQDVVGLELFKDSDLGLTEFAQKVNYQRALQGEVARTLMSLEEVDMARVHLTLPESSIFRRDQVKPKASVTIFPKSSAPLGEDSIRGIQKLVAASVPGMAPGDVIVLDQRGAAATADEIGDVSDPKFALKQAIERSYEKKISEQLARVLRETGATVSVNAEINFDQVQTTRETGIAPPAEAAPRALPPLPVVAGASAAPGAADPLPPLPASSAAAAPAAPVRTNRVLEQIVSAPGTVRRLSVAIVLEREQPAEVVEKVQAVVAASAGIDGKRGDVVSIVVRDPALPVAAAATPVAALPALAAPRAQPVSAATANATAFAAKDVALLGAAGVLLLVGGVAWRALRRREPAARRLSEHEREEFAARLKRLLQEQGDAHVRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNB5</accession>
    <name>A0A0S2DNB5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4733</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60074">
        <property type="protein sequence ID" value="ALN60074"/>
        <property type="gene ID" value="GLE_4733"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4733"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4667"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="74" mass="8322" checksum="7E267CB6A9BDAFDB" modified="2016-02-17" version="1">MNIAARVRAPRRSRQRIAETAAAPPRFSAAPARASPAANAMFAPSRRRRCPSLRRRMRLRRHRPGLAARPGPDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNN1</accession>
    <name>A0A0S2DNN1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Flagellar hook-basal body complex protein FliE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">fliE</name>
        <name evidence="6" type="ORF">GLE_4636</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the FliE family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4636"/>
    <dbReference type="EnsemblBacteria" id="ALN59977">
        <property type="protein sequence ID" value="ALN59977"/>
        <property type="gene ID" value="GLE_4636"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4636"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4572"/>
    <dbReference type="OMA" id="VMAMEQA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00724">
        <property type="entry name" value="FliE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001624">
        <property type="entry name" value="FliE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34653">
        <property type="entry name" value="PTHR34653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02049">
        <property type="entry name" value="FliE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01006">
        <property type="entry name" value="FLGHOOKFLIE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00205">
        <property type="entry name" value="fliE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595454" description="Flagellar hook-basal body complex protein FliE" evidence="5">
        <location>
            <begin position="18"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="104" mass="10755" checksum="E325C435E407D2C1" modified="2016-02-17" version="1">MSIDAIAALSAAQAAAAAPQAAAPAAAPQAAGQDFGSMLLANVMHADASVQAAESAVQAFALDGQAPPHQVMLALEEARMSLHFALQVRNRLVEGYQELMRMQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNN4</accession>
    <name>A0A0S2DNN4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949253.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60051">
        <property type="protein sequence ID" value="ALN60051"/>
        <property type="gene ID" value="GLE_4710"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4710"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4644"/>
    <dbReference type="OrthoDB" id="148722at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="706" mass="76385" checksum="3DF0DB009345F3FE" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNP8</accession>
    <name>A0A0S2DNP8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase</fullName>
            <ecNumber evidence="3">2.5.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_23220</name>
        <name evidence="3" type="ORF">GLE_4772</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.5.1.18" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949303.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4772"/>
    <dbReference type="EnsemblBacteria" id="ALN60113">
        <property type="protein sequence ID" value="ALN60113"/>
        <property type="gene ID" value="GLE_4772"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4772"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4706"/>
    <dbReference type="OMA" id="TIAMWTR"/>
    <dbReference type="OrthoDB" id="1246633at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="89"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="206" mass="23391" checksum="117FA8F1FB7FC8AC" modified="2016-02-17" version="1">MKLYYTPHTCSFAPHIVARELGLPLELRRVRLGAEARVVAEDRDYRELSPLGYVPLLQLDDGRLLREGVAILRYLGDQDPAAGLSAPLGSVERAEQDQWLTFINSELHKTFSPWLFHPEYGEAPGRIAGERLQPRLALVDRHLEGREFLGERFGIADAYLYTVAGWARLLKLDLAPYPNLAAYLTRLDQRPSVREALRAEREDGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNQ4</accession>
    <name>A0A0S2DNQ4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4792</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60133">
        <property type="protein sequence ID" value="ALN60133"/>
        <property type="gene ID" value="GLE_4792"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4792"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4725"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="38" mass="3975" checksum="1950CF26660C9889" modified="2016-02-17" version="1">MSSPVRTRKGRNHRGTPPVGAXXXXXXXAIAAIARVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP07</accession>
    <name>A0A0S2DP07_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/beta fold hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Carboxylesterase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Phospholipase/carboxylesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_03695</name>
        <name evidence="4" type="ORF">FE772_22230</name>
        <name evidence="2" type="ORF">GLE_4555</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000006">
        <property type="protein sequence ID" value="OPD65417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057950296.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4555"/>
    <dbReference type="EnsemblBacteria" id="ALN59896">
        <property type="protein sequence ID" value="ALN59896"/>
        <property type="gene ID" value="GLE_4555"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65417">
        <property type="protein sequence ID" value="OPD65417"/>
        <property type="gene ID" value="BV903_03695"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4555"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4491"/>
    <dbReference type="OMA" id="WYDILAM"/>
    <dbReference type="OrthoDB" id="1195966at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
        <property type="entry name" value="Abhydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_2" evidence="1">
        <location>
            <begin position="24"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD65417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="234" mass="25073" checksum="CFC9F6733C9614AF" modified="2016-02-17" version="1">MNNATSDAAVAAPLETVEIETGPQPAWTVLWLHGLGDSGEGWAPVVPELVRKDWPALRFVFPHAPVRAVTINNGARMRAWYDIRDFQDLANRADEAGVEESVAQVEALIAREAGRGVPAARVILAGFSQGGAIALAAGLRRREPLAGLIALSTYLPMADRLVREAAPAASAQPLFMAHGSYDPVVPFQGGEMAAARLRTLGFNIDWHTYPMAHQACAEEIDAVAAWLSQRFAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP95</accession>
    <name>A0A0S2DP95_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Small ribosomal subunit biogenesis GTPase RsgA</fullName>
            <ecNumber evidence="3">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">engC</name>
        <name evidence="3" type="synonym">rsgA</name>
        <name evidence="7" type="ORF">GLE_4786</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4786"/>
    <dbReference type="EnsemblBacteria" id="ALN60127">
        <property type="protein sequence ID" value="ALN60127"/>
        <property type="gene ID" value="GLE_4786"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4786"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4719"/>
    <dbReference type="OMA" id="RFHDCAH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01854">
        <property type="entry name" value="YjeQ_EngC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01820">
        <property type="entry name" value="GTPase_RsgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004881">
        <property type="entry name" value="Ribosome_biogen_GTPase_RsgA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010914">
        <property type="entry name" value="RsgA_GTPase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32120">
        <property type="entry name" value="PTHR32120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03193">
        <property type="entry name" value="RsgA_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00157">
        <property type="entry name" value="TIGR00157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50936">
        <property type="entry name" value="ENGC_GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CP-type G" evidence="6">
        <location>
            <begin position="76"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="ENGC_GTPASE" evidence="5">
        <location>
            <begin position="82"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="120"/>
            <end position="123"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="178"/>
            <end position="186"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN60127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="332" mass="35878" checksum="17084111E49D2DDE" modified="2016-02-17" version="1">MIEQHRSGYVVSDGPDSAGFPVDSLPEWQRPRFPPEQRPGVGDWLLIERAGSRDKVVALLPRHSAIKRGAAGEHYKQQLIAANIDTVFVVCGLDADFNPRRIERYLLLVRGGAEPVIVLTKADAALAADPEAVALATGALVELSQGIQVRAVNARDRDGVLAALSPWLGPGRTVVLVGSSGAGKSTITNSLLGSDRMKTGAVRESDARGRHTTTHRALIPLPSGACLIDTPGMRELKPTGEEDIGENFADVEALAEQCKFRDCSHHREPGCAVRAAIEAGKLDPQRFANYLKLREEVAGAANKLANRRAQKSEEKVLGKALNKRLDEKYGRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPA4</accession>
    <name>A0A0S2DPA4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FE772_23700</name>
        <name evidence="9" type="ORF">GLE_4880</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949385.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4880"/>
    <dbReference type="EnsemblBacteria" id="ALN60221">
        <property type="protein sequence ID" value="ALN60221"/>
        <property type="gene ID" value="GLE_4880"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4880"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4811"/>
    <dbReference type="OMA" id="ANGRYIN"/>
    <dbReference type="OrthoDB" id="71288at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726689" evidence="6">
        <location>
            <begin position="35"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="70"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="7">
        <location>
            <begin position="473"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="268"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN60221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW28202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="1040" mass="112436" checksum="8D99BF063834CF68" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPF4</accession>
    <name>A0A0S2DPF4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridine nucleotide-disulfide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_24030</name>
        <name evidence="2" type="ORF">GLE_5262</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000089">
        <property type="protein sequence ID" value="OPD61373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949675.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000089.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5262"/>
    <dbReference type="EnsemblBacteria" id="ALN60603">
        <property type="protein sequence ID" value="ALN60603"/>
        <property type="gene ID" value="GLE_5262"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61373">
        <property type="protein sequence ID" value="OPD61373"/>
        <property type="gene ID" value="BV903_24030"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5262"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5181"/>
    <dbReference type="OMA" id="LTMIDQV"/>
    <dbReference type="OrthoDB" id="1239213at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038732">
        <property type="entry name" value="HpyO_NAD-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13454">
        <property type="entry name" value="NAD_binding_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_binding_9" evidence="1">
        <location>
            <begin position="5"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="460" mass="49467" checksum="F358801AD5B6705F" modified="2016-02-17" version="1">MRITIVGAGFSGSALASELARNAGPGVELCLVGQPESYGRGIAYGEARPEHLLNVRASDLGATPEAPGGFADWLNLTDRARGSYLPRLLFGEYLHAQLQAAVAGSTAAFSQIRHEAIAVERASAGFRVHLADGSDFLTDKVVLAVGALPPQPLAGVGPRLAVHPSYIGWPWQDGAIDAIAPDARLLIVGTGLTMADVVTTLRKRGHRGPIVALSRHGLLPRAHEDAAPAPVALPPAVLHALDSHAPRELLRALRNLAPVIDDWRSLVDALRPYLQGFWAGMPAAQRGGFLRHLRSYWEALRHRIAPQLAEELQALRESGQLQIRAGRLLRARRGDDAVEALIRERGGQQLRSERFDVLIRATGLDTDVERTTHPLIAHLRESGLVAADPLGLGLRASARFEVLDHKDVAVRGLYAIGPLLRAQLWEITAVPELRVAARDLAGRLLSTAAVARNRPVLATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPI6</accession>
    <name>A0A0S2DPI6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative cyanophycinase</fullName>
            <ecNumber evidence="5">3.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_5060</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S51 family.</text>
    </comment>
    <dbReference type="EC" id="3.-.-.-" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5060"/>
    <dbReference type="EnsemblBacteria" id="ALN60401">
        <property type="protein sequence ID" value="ALN60401"/>
        <property type="gene ID" value="GLE_5060"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5060"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4988"/>
    <dbReference type="OMA" id="FIARQIQ"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005320">
        <property type="entry name" value="Peptidase_S51"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03575">
        <property type="entry name" value="Peptidase_S51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595937" evidence="4">
        <location>
            <begin position="36"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="381" mass="40957" checksum="216AD3BD9DA3BE7F" modified="2016-02-17" version="1">MRSSSMWSLSALRRKTLAGLWLAAGLACATLGAYAQAPAGGADPAQRDGYRYYEIGRLDAPRPQPTRAGLMLVGGGDWPREAFAWMVERAGHGRIVILRASGTVEAQNEFFHDIGGITGAQTLVFQDRRAASDPQVLDIVRQADGIFIAGGDQSRYVRFWKDTPLARALDAHVRAGKPIGGTSAGLAILGAYAYGAMDGGSVVSQTALDDPAGPMLTMVDDFLHLPYLHNVVTDSHFGKRQRLGRLIAFLARLSKEHGRHDLVGLGVDEYTALCIDAHGEGSVFSGNGGKVWLVKPRQPARVFAQGEPLSQRAVPVIGIGEGSALRMRDFKVERPAFVELYDVESGQLILREDPADGDAAREGLRLPNLSYGADDDELVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPM0</accession>
    <name>A0A0S2DPM0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA polymerase sigma factor, sigma-70 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Sigma-70 family RNA polymerase sigma factor</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BV903_16545</name>
        <name evidence="8" type="ORF">FE772_24520</name>
        <name evidence="6" type="ORF">GLE_5059</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">C3</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000044">
        <property type="protein sequence ID" value="OPD62785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949523.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000044.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5059"/>
    <dbReference type="EnsemblBacteria" id="ALN60400">
        <property type="protein sequence ID" value="ALN60400"/>
        <property type="gene ID" value="GLE_5059"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62785">
        <property type="protein sequence ID" value="OPD62785"/>
        <property type="gene ID" value="BV903_16545"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5059"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4987"/>
    <dbReference type="OMA" id="VRKCFIL"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="4">
        <location>
            <begin position="16"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="5">
        <location>
            <begin position="110"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="172"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN60400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD62785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW28341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="208" mass="23686" checksum="72CA333A6ECE63B7" modified="2016-02-17" version="1">MDTDLDAWFAADILVHEAALVQYLRRVWPHPDEIHDLRQEVYVRVYEAAGKARPHQPKPFLFATARHLMTDRLRRGRVVSIEPVGDFESLNVLIDECSPERRLGARQNLRRLAEAFDRLPQRCREAVWLRRVEELPQKQVAQRMGITEKTVEKQIAKGMRLLAEHYFGGEAQADGAGAQGRARREAAHPSATDEGTHGQDGHGRKQGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPN3</accession>
    <name>A0A0S2DPN3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutaredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_4795</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949320.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4795"/>
    <dbReference type="EnsemblBacteria" id="ALN60136">
        <property type="protein sequence ID" value="ALN60136"/>
        <property type="gene ID" value="GLE_4795"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4795"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4728"/>
    <dbReference type="OMA" id="QPSMPQC"/>
    <dbReference type="OrthoDB" id="2001991at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097573">
        <property type="term" value="F:glutathione oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03028">
        <property type="entry name" value="GRX_PICOT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033658">
        <property type="entry name" value="GRX_PICOT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="PTHR10293"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="SSF89360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00365">
        <property type="entry name" value="TIGR00365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="4">
        <location>
            <begin position="220"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="308" mass="32737" checksum="138DC834C533DB04" modified="2016-02-17" version="1">MSLTPELRSRIESLLQSNRVVLFMKGAPDAPQCGFSAKAAGTLNALLPQGYAHVDVLGDGEIREGIKAYGEWPTIPQLYIDGQLVGGSDIILQMAGNGELHGLLGLAAPDRSPPKLEISPAAAKMLREAVAGAGEGYAVQLEVDARHNVRLQLAPVDADAVAVEIDGVRVQTDWINARRADGVSIDWADDERGRGLVITNPNAPPAVRSIAPADVRERVQAGSLRLIDVRPADERALAQADVAFDTFDHGTDALEGLPKDAPIAFLCHRGGRSAQAAEQFRQLGFREVYNVVGGIDAWADLGGGIAKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPS4</accession>
    <name>A0A0S2DPS4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Phospholipase D Active site motif</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLE_5321</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60662.1"/>
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            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
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        <location>
            <begin position="46"/>
            <end position="68"/>
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            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
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        <source>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN60662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="478" mass="53817" checksum="4C605C6F87061E8C" modified="2016-02-17" version="1">MPDSLTAVWQDLIHIPHIGFYLTAGWAVYLVWLGTWIVLQKREPVATLSWLFSLALLPYIGFLIYFFFGPQRIHRQRLRRVRARAALPPPPPGLTPSPEAIELSRLGQATTGLPPTTATDARLLIDGGAKYASLLADIAQAREHIHLEYYIYQPDGIGTALRDALVERARAGVKVRLLLDAVGSGSTSKRFLQPLLDAGGEAAWFHPMKLRWFWHRPWLNLRTHRKIVVIDGRVGYTGGINITDEEDERARKDAYRDLHLRLEGDVVRELELVFIEDWCYATGQPPLKQLHLAPQPGTIAAQVVSSGPDSNWEAIHRVHVGAIHAARRRVWLVTPYFVPGEAARMALTSAALGGLDVRLLVPKLSDSRLVTYAARSYFDELLEAGVKIHEYGPRMLHTKALLCDDESVIIGSANFDHRSFRLNFEISVMFYNADVAGRLATLIEQECSRAPRVRNDRNRSLWRVRLPEALARLVSPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPX3</accession>
    <name>A0A0S2DPX3_LYSEN</name>
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        <submittedName>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_5171"/>
    <dbReference type="EnsemblBacteria" id="ALN60512">
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        <property type="gene ID" value="GLE_5171"/>
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    </dbReference>
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            <begin position="9"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="115" mass="12462" checksum="0BDEE1F6F964BDF0" modified="2016-02-17" version="1">MSDSHQELLFSYGTLQLAAVQQATFGRLLQGEPDALVGFRRTMVKIDDPQVVATSGETHHPIVAASGDAADRVAGTVFAISAAELAHADEYEVDDYRRVEAELASGRRAWVYVQA</sequence>
</entry>
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    <accession>A0A0S2DPY0</accession>
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    <protein>
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        <lineage>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60604">
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        <property type="gene ID" value="GLE_5263"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5263"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5182"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="47" mass="4857" checksum="E6D9AA0A161A02BB" modified="2016-02-17" version="1">MLIASETKVSELKSLPQERSAQAHAAVVGGPSGPTLSDPPASDVDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ32</accession>
    <name>A0A0S2DQ32_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_00785</name>
        <name evidence="1" type="ORF">GLE_5518</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW24419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949857.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60859">
        <property type="protein sequence ID" value="ALN60859"/>
        <property type="gene ID" value="GLE_5518"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5518"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5432"/>
    <dbReference type="OrthoDB" id="2065980at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="64" mass="7059" checksum="811270EF7C1E80B5" modified="2016-02-17" version="1">MSSPNDADLWFLKAIAATVLVAAANGTLDLNERARDELIRRGLDPEGEWVGPSRARELHYPTPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ51</accession>
    <name>A0A0S2DQ51_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Blue copper oxidase CueO</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">cueO</name>
        <name evidence="6" type="ORF">GLE_5074</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949534.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5074"/>
    <dbReference type="EnsemblBacteria" id="ALN60415">
        <property type="protein sequence ID" value="ALN60415"/>
        <property type="gene ID" value="GLE_5074"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5074"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5001"/>
    <dbReference type="OMA" id="LLPKQWG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="3"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    <evidence type="ECO:0000259" key="4">
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            <dbReference type="Pfam" id="PF07732"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN60415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="544" mass="60124" checksum="24045522ADEA65F2" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQF2</accession>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Fernandez C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Feng T."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <source>
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        <source>
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</entry>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome"/>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
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    </evidence>
    <sequence length="43" mass="4972" checksum="DDCE3773479CABAE" modified="2016-02-17" version="1">MFFSPPLSTSTTLNSVDPKLNRLRRFFHLRQAIPDKSMLLSAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQI9</accession>
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </evidence>
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        <source>
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        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="71" mass="7627" checksum="ADCBAB8173A33361" modified="2016-02-17" version="1">MRSIRRHTLIFAAAFALAAGFAGGAAAQRNCSICTGIYDNCMAKPDASEYECVLEHNRCAKSLGCPFKPQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQQ6</accession>
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        <submittedName>
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    </protein>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="entry name" value="Galactose-bd-like_sf"/>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN60801.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
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    </evidence>
    <sequence length="585" mass="60546" checksum="F992DD6994B7126A" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA64</accession>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_0087"/>
    <dbReference type="EnsemblBacteria" id="ALN55446">
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        <property type="gene ID" value="GLE_0087"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0087"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.92"/>
    <dbReference type="OMA" id="MCGLIKR"/>
    <dbReference type="OrthoDB" id="1497607at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
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    </dbReference>
    <dbReference type="GO" id="GO:0005840">
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        <property type="project" value="UniProtKB-KW"/>
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    <keyword evidence="2" id="KW-0808">Transferase</keyword>
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            <begin position="9"/>
            <end position="169"/>
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    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="179" mass="19338" checksum="475A6D43D922E0F2" modified="2016-02-17" version="1">MPTIHTDRLTLRELAAGDAGFILELLNEPGFLGGIGDRGVRDLDGALRYIHDGPAASYARHGFGLWRVELREGGEPIGLCGLLRRDTLPDPDLGYAFLQRHWQRGYAVEAGEAVLRYAGATLALPRVLAIVNPDNASSIKVLERLGMRAQGTIRHGTENRDVRLYATAEVDAGADAAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA67</accession>
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        <submittedName>
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        </submittedName>
    </protein>
    <gene>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="QCW24511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945775.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55434">
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        <property type="gene ID" value="GLE_0075"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0075"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.80"/>
    <dbReference type="OMA" id="ACFSVAF"/>
    <dbReference type="OrthoDB" id="626204at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:transmembrane transporter activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS"/>
    </dbReference>
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        <property type="entry name" value="MFS_dom"/>
    </dbReference>
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        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TCRTETA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="15"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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        </location>
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            <end position="132"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="5">
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        </location>
    </feature>
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        <location>
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        </location>
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            <begin position="15"/>
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        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
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    </evidence>
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        </source>
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        </source>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW24511.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="425" mass="45124" checksum="AC2AF6A6B4CCC1BC" modified="2016-02-17" version="1">MTSASAPASGARRAALVFIFITVLIDVLSFGLIIPVLPHLIEKFVDGDTAIAAYWVGVFGTVFALVQFLFSPIQGSLSDRYGRRPVILLSCLGLGLDFLLMAVADSLPLLLIGRIISGITAASFTTANAYIADITAPEQRAKSFGMIGAAFGVGFVIGPLIGAYLGEVDLRLPFWFAAGLALLNFLYGLFVLPESLPPQRRSARFDWAHANPFGALLLLKRYPQVFGLAAVVFVANVAHYVYPSIFVLFADYQYHWGLREVGWALLVVGVFNVVVNVALIGRAVARLGERRTLLLGLACGVAGFVIYGLADHGWLFLLGLPISALWAMATPATQALLTRQVDADAQGRIQGALMSLIALAGVVGPGLYAGSFGYFIGPHAPVHLPGVPWFIAAALLALGWLIAWRYARVPPAPAPPAAGAAEALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAC7</accession>
    <name>A0A0S2DAC7_LYSEN</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_01095</name>
        <name evidence="1" type="ORF">GLE_0032</name>
    </gene>
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        <lineage>
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            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW24477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_0032"/>
    <dbReference type="EnsemblBacteria" id="ALN55391">
        <property type="protein sequence ID" value="ALN55391"/>
        <property type="gene ID" value="GLE_0032"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0032"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.39"/>
    <dbReference type="OrthoDB" id="1942480at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="311" mass="34028" checksum="EFF500565C2567D5" modified="2016-02-17" version="1">MAYTTAIASDPNELLDKLRVFAQGNGWSVDGWRDRTVKAGKALSVHADSLFVTFLSELAAGDSARPGPFVGAFGHTGYATHANADVQAEASGPVWANYAQGPYSAVHFFGRTAPQPYLHVVLETQAGTFKHFGTGRLVTRGIVNTGQYVYGSQWYYDDSYVNSPDDGRHAIAFDDSFTNYLTTATRVRADYDGMAPRWHAVSDTGSDPRALYCGWRRRAAPINLLKEFGHSTLTGRAPGQPLWCAVPRGGDLSTDVGHPPDLRFIRLDSYAPGEELVLGSDRWKMFPVHRKNGPVGTPNSGVYGYAYRITE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAD8</accession>
    <name>A0A0S2DAD8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Membrane protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="11">Trimeric intracellular cation channel family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BV903_24740</name>
        <name evidence="11" type="ORF">FE772_01655</name>
        <name evidence="9" type="ORF">GLE_0151</name>
    </gene>
    <organism evidence="9 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">C3</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0126 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000098">
        <property type="protein sequence ID" value="OPD61236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945833.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000098.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55510">
        <property type="protein sequence ID" value="ALN55510"/>
        <property type="gene ID" value="GLE_0151"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61236">
        <property type="protein sequence ID" value="OPD61236"/>
        <property type="gene ID" value="BV903_24740"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0151"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.153"/>
    <dbReference type="OMA" id="MPKFDYQ"/>
    <dbReference type="OrthoDB" id="1665397at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005115">
        <property type="entry name" value="Gly_transporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03458">
        <property type="entry name" value="Gly_transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Gly_transporter" evidence="8">
        <location>
            <begin position="5"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Gly_transporter" evidence="8">
        <location>
            <begin position="90"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN55510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD61236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW24572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="201" mass="21696" checksum="E99D14561C2206A4" modified="2016-02-17" version="1">MLLQIIYLIAISAEAMTGALAAGRRRMDLFGVVIIACVTALGGGSLRDIVLGHYPLGWVRHPEYLGYTVGAAFAATFLAKKLHYLRRTFLWLDALGLIAFTLIGCAVAREAGHQPAIVVVAGMLTGAFGGVLRDVLCNEIPLVFQRELYAVISLLTGVAYLALLRLGVAENVAVLACLGGGFAVRLLAIRYEWEMPKFVYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAN3</accession>
    <name>A0A0S2DAN3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Acyl-CoA desaturase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Fatty acid desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BV903_24710</name>
        <name evidence="11" type="ORF">FE772_01630</name>
        <name evidence="9" type="ORF">GLE_0144</name>
    </gene>
    <organism evidence="9 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">C3</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000098">
        <property type="protein sequence ID" value="OPD61228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945828.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000098.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0144"/>
    <dbReference type="EnsemblBacteria" id="ALN55503">
        <property type="protein sequence ID" value="ALN55503"/>
        <property type="gene ID" value="GLE_0144"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61228">
        <property type="protein sequence ID" value="OPD61228"/>
        <property type="gene ID" value="BV903_24710"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0144"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.146"/>
    <dbReference type="OMA" id="AQNTREW"/>
    <dbReference type="OrthoDB" id="797871at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016717">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03505">
        <property type="entry name" value="Delta9-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015876">
        <property type="entry name" value="Acyl-CoA_DS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351">
        <property type="entry name" value="PTHR11351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00075">
        <property type="entry name" value="FACDDSATRASE"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="FA_desaturase" evidence="8">
        <location>
            <begin position="19"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN55503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD61228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW24567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="398" mass="45657" checksum="45EBD69D53117127" modified="2016-02-17" version="1">MPASLIDFLAGGLVQARFWELAVYFLVVTQLTILSVTLYLHRSMAHRSVDFHPVLAHFFRFWTWLTTSMITKEWAAIHRKHHAKCETEEDPHSPQFKGIDTVMWRGVELYREARTEREDIEKYGKGCPDDWIERKLYTPWATMGPVVLLFASFALFGFAGVAIWALQMVWIPFWAAGVVNGLGHWWGYRNFETTDTATNLTPWGFWIGGEELHNNHHAFPSSAKFALRKWEFDIGWTAIRGLAALRLAKVLRVAPTLDVRPNIAMPDGETLKALLAIRFQAMTDFYRNVTLPTLREDAGDRVRALPRRLRKGLADGGRWLDDGARARLQTWVAERPRMAQLADFRQRLAQVLDDRSHDAQATLQRLHAWCVEAEASGIHTLQAFSERLKGYALAPVRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAU0</accession>
    <name>A0A0S2DAU0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0158</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55517">
        <property type="protein sequence ID" value="ALN55517"/>
        <property type="gene ID" value="GLE_0158"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0158"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.160"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="53" mass="5482" checksum="73370E91093E4AD2" modified="2016-02-17" version="1">MRVVAAAASRPWIFAANPKFAVAACAAPTGSPGRSGASRERATTPTAPSERRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAV7</accession>
    <name>A0A0S2DAV7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55676">
        <property type="protein sequence ID" value="ALN55676"/>
        <property type="gene ID" value="GLE_0318"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0318"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.315"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="92" mass="10314" checksum="7DBC324B8257018D" modified="2016-02-17" version="1">MPPRSRRGHIADDGNTRAACAHRLRPTRFIEFSGAPMPCASDARACRRARDSVTPNAFRSERRISPFVVVGKPSQRQSRHSHAAYCEKVKNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB47</accession>
    <name>A0A0S2DB47_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase_C39_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_02805</name>
        <name evidence="3" type="ORF">GLE_0402</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946008.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0402"/>
    <dbReference type="EnsemblBacteria" id="ALN55760">
        <property type="protein sequence ID" value="ALN55760"/>
        <property type="gene ID" value="GLE_0402"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0402"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.399"/>
    <dbReference type="OMA" id="IQWSSGG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039564">
        <property type="entry name" value="Peptidase_C39-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13529">
        <property type="entry name" value="Peptidase_C39_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726522" description="Peptidase_C39_2 domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_C39_2" evidence="2">
        <location>
            <begin position="26"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="181" mass="20538" checksum="5DFD64969489F35C" modified="2016-02-17" version="1">MNLKNKLSTAALLALAALGTASAGVLNVPLYKQEHSNWCWAASASMIMSYHGKWVTQCSMANYSFGINYACGNNTFYWNSYANQGNWNYDVDDAMNYFWGSQRFYQQNGYLSQANLKARIDANKPFIMSWRWSSGGAHDVVVTGYSGNYVYFNDPWDGSYYRTYAATVSATDRQWEDSLLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBB8</accession>
    <name>A0A0S2DBB8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable GTP-binding protein EngB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">engB</name>
        <name evidence="10" type="ORF">GLE_0335</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Necessary for normal cell division and for the maintenance of normal septation.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0335"/>
    <dbReference type="EnsemblBacteria" id="ALN55693">
        <property type="protein sequence ID" value="ALN55693"/>
        <property type="gene ID" value="GLE_0335"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0335"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.332"/>
    <dbReference type="OMA" id="LMMDIRH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01876">
        <property type="entry name" value="YihA_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00321">
        <property type="entry name" value="GTPase_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030393">
        <property type="entry name" value="G_ENGB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019987">
        <property type="entry name" value="GTP-bd_ribosome_bio_YsxC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03598">
        <property type="entry name" value="GTPase_YsxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51706">
        <property type="entry name" value="G_ENGB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0717">Septation</keyword>
    <feature type="domain" description="EngB-type G" evidence="9">
        <location>
            <begin position="26"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN55693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="213" mass="23428" checksum="1D29F0F6C1E3CC0A" modified="2016-02-17" version="1">MGMSNPLARARYLLSAHNVKQLPPDGGFEVAFAGRSNAGKSSALNALCQQNALARVSKTPGRTQQLVFFDVSPLHRGPEPAPEPDRFLVDLPGYGYAKVPQDLQAHWQAFLDRYFQTRQALRGLVVVMDIRHPLKDYDRQMIAYAVNRGLPAHALLTKADKFGRGQQQQALMAVRKDLHASYGDTVSVQTFSGESKQGVDEARAVVGGWLELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBJ0</accession>
    <name>A0A0S2DBJ0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0551"/>
    <dbReference type="EnsemblBacteria" id="ALN55909">
        <property type="protein sequence ID" value="ALN55909"/>
        <property type="gene ID" value="GLE_0551"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0551"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.545"/>
    <dbReference type="OMA" id="DANACFR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594889" evidence="1">
        <location>
            <begin position="29"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="300" mass="32750" checksum="5D68B5824DBE9C0E" modified="2016-02-17" version="1">MKIHRRGARAALLSLAVACACAVGPACAQAPAQTAPAAPTAPTAPAAAKLYDSFTLDSKILGETRRINVYAPPAYAARGRDRHPVLYMPDGGLQEDFPHVADAVDRAIADGAIAPMFVVGIENTQRKRDMTGPTEVAEELKLAPTLGGSAQFRAFIRDELIPQVERRLRTDARRGIVGESLAGLFVAETFLREPRLFDVYIAISPSLWWNRDALLTQAPALLRENLKALPRRTLRLYSADEDNIAPQTQRLADLLRAQAPAGLTWGYWPRPDLTHGTIYRAVEDESIRAAFAAPARAPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-08-12" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBS4</accession>
    <name>A0A0S2DBS4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TetR/AcrR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_03680</name>
        <name evidence="3" type="ORF">GLE_0599</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55957">
        <property type="protein sequence ID" value="ALN55957"/>
        <property type="gene ID" value="GLE_0599"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0599"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.591"/>
    <dbReference type="OMA" id="IRCEHVM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041586">
        <property type="entry name" value="PsrA_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17939">
        <property type="entry name" value="TetR_C_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
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    </dbReference>
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        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="268" mass="29346" checksum="DA3B18702395BA7F" modified="2016-02-17" version="1">MNNPRANSSDTRRRLLEAAEALFIRHGYEGMLLRQITSEAKVNLAAVNYHFGSKEALVQELLSSRLDRLNAERLQLLSLCEERFGAATLDAPTVLGILFVPAVRLSRDSAGGISFMRLLGRVYSDPSPFVRGFLYEHYQPIYERFFEAFARALPHQSRNELGTRLHFALKALSGVLAGENMDELIAAICVGEAVSDSLMLGRLVAFVSPLLTTPFDNLAQVRQVEQVMGLAPAAAQAADATLRADGEPAAGRKPRGILPLWAEKVVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCD3</accession>
    <name>A0A0S2DCD3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_0837</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0837"/>
    <dbReference type="EnsemblBacteria" id="ALN56195">
        <property type="protein sequence ID" value="ALN56195"/>
        <property type="gene ID" value="GLE_0837"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0837"/>
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    <dbReference type="OMA" id="ADDGHTF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="762" mass="82587" checksum="F0B4B2EFF738D3FD" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCM2</accession>
    <name>A0A0S2DCM2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Guanylate kinase</fullName>
            <ecNumber evidence="2 9">2.7.4.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">GMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 11" type="primary">gmk</name>
        <name evidence="12" type="ORF">BV903_19750</name>
        <name evidence="13" type="ORF">FE772_05205</name>
        <name evidence="11" type="ORF">GLE_0910</name>
    </gene>
    <organism evidence="11 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">C3</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">B25</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential for recycling GMP and indirectly, cGMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + GMP = ADP + GDP</text>
            <dbReference type="Rhea" id="RHEA:20780"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the guanylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.8" evidence="2 9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000057">
        <property type="protein sequence ID" value="OPD62225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946388.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000057.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0910"/>
    <dbReference type="EnsemblBacteria" id="ALN56268">
        <property type="protein sequence ID" value="ALN56268"/>
        <property type="gene ID" value="GLE_0910"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62225">
        <property type="protein sequence ID" value="OPD62225"/>
        <property type="gene ID" value="BV903_19750"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0910"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.898"/>
    <dbReference type="OMA" id="EWAVVHG"/>
    <dbReference type="OrthoDB" id="1502854at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004385">
        <property type="term" value="F:guanylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00328">
        <property type="entry name" value="Guanylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017665">
        <property type="entry name" value="Guanylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020590">
        <property type="entry name" value="Guanylate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03263">
        <property type="entry name" value="guanyl_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00856">
        <property type="entry name" value="GUANYLATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Guanylate kinase-like" evidence="10">
        <location>
            <begin position="3"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="10"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN56268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OPD62225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW25152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="206" mass="23096" checksum="E5D8BE58EBE3467F" modified="2016-02-17" version="1">MRGTLYIVAAPSGAGKSSIVNAVLARDPNIRLSISFTSRKPRPGERHAEHYHFVSEQEFEAMVAEGDFFEHARVHGDWKGSARQSVEPFLSAGKDVLLEIDWQGARQVRKKVPDAVSVFILPPSRQALESRMRSRGQDTEEVIGQRLAAARDEMSHYGEFDYVIVNEIFDTAVDEMCAIFTASRLRREAQVARHSRLITALLVDEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="3 4">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="gene ID" value="GLE_0928"/>
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            <begin position="1"/>
            <end position="43"/>
        </location>
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            <begin position="44"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="337" mass="36090" checksum="F78B5FA7FCABBA86" modified="2016-02-17" version="1">MQGSQTRTASAADSRHPRRLLHDMLLAAALASAMLAATPAAVADTGATPATSASPASAKPRPAPAARASAAVSTVADLVARLRTRAAASQRSPAVRADYLALLRAQGLSEQQLPYPDFAWLRLLFEASRDGGYWNLRWAITDREPNSDAIWRQWQSVRAPAPDRATAVAECDELSAFYAVLARLGGVGGVGLLWPTSNHTVAVWSRPGPPREARIVVPTTLIFLGRNDSFGTRGFDPWKQKRIYPYTRADIAPSQRLPPALAAFLIAQADRYADASGLSLQRLRELREGVLKGSLGAAEAASQARRQRDALPAGAQADLAAYAHFIAAMRGRGPELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCS8</accession>
    <name>A0A0S2DCS8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0968</name>
    </gene>
    <organism evidence="2 3">
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN56326">
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        <property type="gene ID" value="GLE_0968"/>
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    <dbReference type="KEGG" id="lez:GLE_0968"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="366" mass="39259" checksum="BA777ABCB54156A7" modified="2016-02-17" version="1">MALAACGRDPQAPPAAAVTLGSQNETPKPAPAAVSEEDILKGTYWPPAKLDGGSARISCEYDYPRFGDGDTLESLDFFSLVDAMSPCQQRGVVRVRYQGKIGAGFTALTQRVAAMAARMEIPTRILDIDSSGGHVEEALRAGDSIAESGWAIWVRENSVCHSACVLVLAAGDTRSIEGKVGIHRLMRDRSTATSRAELSRELRAINQQVRDYLERNGVATAVSDLMMTVANRDLRILTPDELKQYGLDGTNAAQDDLDRIRLARKCGDDFVRRRESFRRAFDAQCMGTGKSFESMPECAEQLQAQFGFPDKACPGESPADLYARDLPPPLLDEAAAGEGAAEPADGKPAGAAGKNEPPAKADKAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCT6</accession>
    <name>A0A0S2DCT6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
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        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">gapA</name>
        <name evidence="11" type="synonym">gap</name>
        <name evidence="11" type="ORF">FE772_05440</name>
        <name evidence="10" type="ORF">GLE_0962</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
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    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946426.1">
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    <dbReference type="STRING" id="69.GLE_0962"/>
    <dbReference type="EnsemblBacteria" id="ALN56320">
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        <property type="gene ID" value="GLE_0962"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0962"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.949"/>
    <dbReference type="OMA" id="NCVAPMA"/>
    <dbReference type="OrthoDB" id="944149at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10836">
        <property type="entry name" value="PTHR10836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <feature type="domain" description="Gp_dh_N" evidence="9">
        <location>
            <begin position="3"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="151"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="211"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="12"/>
            <end position="13"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="80"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="316"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Activates thiol group during catalysis" evidence="6">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU361160"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN56320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW25184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="334" mass="36027" checksum="8AEFE1D4C58BA9FF" modified="2016-02-17" version="1">MTIKVGINGFGRIGRNVLRAAVQNFDGEIEIVAINDLLEPDYLAYMLQYDSVHGRFKGTIAVEGNTLVVNGKKIRLTQERDPANLKWDEVGAEVVIESTGLFLDKATAQKHLDAGAKKVVLSAPSKDDTPMFVYGVNDKTYQGEAIVSNASCTTNCLAPLAKVLNDKWGIKRGLMTTVHAATATQKTVDGPSNKDWRGGRGILENIIPSSTGAAKAVGVVIPELNKKLTGMSFRVPTSDVSVVDLTVELNKDATYAEICAEMKAQSEGALKGVLGYTEDKVVATDFRGDARTSIFDADAGIALDGTFVKLVSWYDNEWGYSNKCLEMVKVVVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCT7</accession>
    <name>A0A0S2DCT7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_05360</name>
        <name evidence="2" type="ORF">GLE_0945</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56303">
        <property type="protein sequence ID" value="ALN56303"/>
        <property type="gene ID" value="GLE_0945"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0945"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.933"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="120" mass="14368" checksum="F9DB3E4A6C57D615" modified="2016-02-17" version="1">MIRDLRKARRPAGFFFARRFVWERRESRPRKRSYCVGFVLVTWLATWLQSDTNRNGRHSGERRNPTEAMKSRRYVPKQQIAPGRHSGERWNATEAMKSRRYVPKQQIAPGRHSGERRNPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCX4</accession>
    <name>A0A0S2DCX4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Thiazole synthase</fullName>
            <ecNumber evidence="4 6">2.8.1.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">thiG</name>
        <name evidence="9" type="ORF">FE772_05635</name>
        <name evidence="8" type="ORF">GLE_1006</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + [sulfur-carrier protein ThiS]-C-terminal Gly-NH-CH2-C(O)SH = 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + [sulfur-carrier protein ThiS]-C-terminal Gly-Gly + 2 H(+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:26297"/>
            <dbReference type="Rhea" id="RHEA-COMP:12908"/>
            <dbReference type="Rhea" id="RHEA-COMP:12909"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
            <dbReference type="ChEBI" id="CHEBI:77846"/>
            <dbReference type="ChEBI" id="CHEBI:90619"/>
            <dbReference type="ChEBI" id="CHEBI:90778"/>
            <dbReference type="EC" id="2.8.1.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotetramer. Forms heterodimers with either ThiH or ThiS.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ThiG family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.10" evidence="4 6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946459.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1006"/>
    <dbReference type="EnsemblBacteria" id="ALN56364">
        <property type="protein sequence ID" value="ALN56364"/>
        <property type="gene ID" value="GLE_1006"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1006"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.994"/>
    <dbReference type="OMA" id="PHNFQLI"/>
    <dbReference type="OrthoDB" id="784095at2"/>
    <dbReference type="UniPathway" id="UPA00060"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04728">
        <property type="entry name" value="ThiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00443">
        <property type="entry name" value="ThiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033983">
        <property type="entry name" value="Thiazole_synthase_ThiG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008867">
        <property type="entry name" value="ThiG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34266">
        <property type="entry name" value="PTHR34266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05690">
        <property type="entry name" value="ThiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="5 6" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ThiG" evidence="7">
        <location>
            <begin position="12"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="DXP binding" evidence="6">
        <location>
            <begin position="193"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="DXP binding" evidence="6">
        <location>
            <begin position="215"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with DXP" evidence="6">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN56364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW25217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="264" mass="27896" checksum="E93E067AD5DFC03F" modified="2016-02-17" version="1">MTDTAFSDPLVIAGKTYRSRLLTGTGKFKDLTETRLATEAAAAEIVTVAIRRTNIGQNPGEPNLLDVLPPDRYTLLPNTAGCYTADDAVRTCRLARELLDGHTLVKLEVLGDQRTLFPDVIQTLAAAETLVKDGFDVMVYTSDDPILAKRLEEIGCVAVMPLAAPIGSGLGVQNKYNLLEIVENAKVPIIVDAGVGTASDAAIAMELGCHGVLMNTAIAGARDPILMAHAMKLAVEAGRAAFLAGRIPRKRYASASSPVDGLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD70</accession>
    <name>A0A0S2DD70_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_06270</name>
        <name evidence="1" type="ORF">GLE_1149</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946554.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56507">
        <property type="protein sequence ID" value="ALN56507"/>
        <property type="gene ID" value="GLE_1149"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1149"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1134"/>
    <dbReference type="OMA" id="ERAVINH"/>
    <dbReference type="OrthoDB" id="1821827at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="189" mass="20470" checksum="444947F274C75023" modified="2016-02-17" version="1">MAAVSLLEMLLLRRALARPAPAPADADEPAPPTDQEPAVANEFEFLDKHYDPTDLPEIAAQTALERFGNYPNARTSTVIFGVAWQALTESIQHAVLNYNNGGIYDAPVAAVLSEDANQWQIILTGLRFVNATRTMVGGRPQYTVSEYSNGSIFLTAQALGGQALGEIVHLGNGFGDWVQDVELKNPPTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDG5</accession>
    <name>A0A0S2DDG5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4153 domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_06395</name>
        <name evidence="2" type="ORF">GLE_1174</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1174"/>
    <dbReference type="EnsemblBacteria" id="ALN56532">
        <property type="protein sequence ID" value="ALN56532"/>
        <property type="gene ID" value="GLE_1174"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1174"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1159"/>
    <dbReference type="OMA" id="WALWLRI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025291">
        <property type="entry name" value="DUF4153"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13687">
        <property type="entry name" value="DUF4153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="294"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="362"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="609" mass="66370" checksum="B489B7148D573DCB" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDI9</accession>
    <name>A0A0S2DDI9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">prpC</name>
        <name evidence="9" type="ORF">FE772_06935</name>
        <name evidence="8" type="ORF">GLE_1289</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16845"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5 7">Belongs to the citrate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946662.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1289"/>
    <dbReference type="EnsemblBacteria" id="ALN56646">
        <property type="protein sequence ID" value="ALN56646"/>
        <property type="gene ID" value="GLE_1289"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1289"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1272"/>
    <dbReference type="OMA" id="NEAVMHM"/>
    <dbReference type="OrthoDB" id="1412360at2"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00717"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036440">
        <property type="term" value="F:citrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011278">
        <property type="entry name" value="2-MeCitrate/Citrate_synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024176">
        <property type="entry name" value="Citrate_synthase_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739">
        <property type="entry name" value="PTHR11739"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001369">
        <property type="entry name" value="Citrate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="SSF48256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01800">
        <property type="entry name" value="cit_synth_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 7" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="270"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001369-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN56646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW25439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="384" mass="42328" checksum="7FADCDF359B63D8E" modified="2016-02-17" version="1">MSDNATQVLPKAKKSVALSGTAAGNTALCTVGRSGNDLHYRGYDIHDLATKSTFEEVSHLLVHGVLPTASQLKAYKTKLKRLRGLPAIVTDALELVPANAHPMDVLRTGCSVLGTVLPEREGHPASEARDIADRLIASFGSMLLYWWHFTRNGRRIECETDDDSVAAHFLHLLHGEPPSQLLADSLDKSLILYAEHEFNASTFTARVIAGTGSDLHSCITGAIGALRGPKHGGANEVAMDIISRYNSAEEAETDIRARVERKEIVIGFGHPVYTVGDPRNPIIKEISRALCKDGGNQVLFDVSERIETLMWDMKKMFPNLDWYSASAYHMMGIPTPMFTPLFVIARTTGWSAHVIEQREDGKIIRPSANYTGPEDREYVPIEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDJ2</accession>
    <name>A0A0S2DDJ2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3-hydroxybutyrate dehydrogenase</fullName>
            <ecNumber evidence="2 3">1.1.1.30</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="2">D-beta-hydroxybutyrate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">bdh</name>
        <name evidence="3" type="synonym">bdhA</name>
        <name evidence="4" type="ORF">BV903_09925</name>
        <name evidence="5" type="ORF">FE772_06820</name>
        <name evidence="2" type="ORF">GLE_1263</name>
        <name evidence="3" type="ORF">LEN_3668</name>
        <name evidence="6" type="ORF">SAMN05421681_102351</name>
    </gene>
    <organism evidence="2 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 7">C3</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2016" name="DNA Res." volume="0" first="0" last="0">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer, Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M497-1</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="3">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">ATCC 29487</strain>
        </source>
    </reference>
    <reference evidence="3 10" key="4">
        <citation type="journal article" date="2017" name="DNA Res." volume="24" first="169" last="177">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
            <dbReference type="PubMed" id="28065880"/>
            <dbReference type="DOI" id=".1093/dnares/dsw055"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 10">M497-1</strain>
        </source>
    </reference>
    <reference evidence="4 9" key="5">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">B25</strain>
        </source>
    </reference>
    <reference evidence="5 11" key="6">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 11">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.30" evidence="2 3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP014940">
        <property type="protein sequence ID" value="BAV99155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000021">
        <property type="protein sequence ID" value="OPD64184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNOG01000002">
        <property type="protein sequence ID" value="SDW61513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946640.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1263"/>
    <dbReference type="EnsemblBacteria" id="ALN56620">
        <property type="protein sequence ID" value="ALN56620"/>
        <property type="gene ID" value="GLE_1263"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAV99155">
        <property type="protein sequence ID" value="BAV99155"/>
        <property type="gene ID" value="LEN_3668"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64184">
        <property type="protein sequence ID" value="OPD64184"/>
        <property type="gene ID" value="BV903_09925"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDW61513">
        <property type="protein sequence ID" value="SDW61513"/>
        <property type="gene ID" value="SAMN05421681_102351"/>
    </dbReference>
    <dbReference type="KEGG" id="lem:LEN_3668"/>
    <dbReference type="KEGG" id="lez:GLE_1263"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1247"/>
    <dbReference type="OMA" id="RSHVICP"/>
    <dbReference type="OrthoDB" id="1094766at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000183696">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000218824">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003858">
        <property type="term" value="F:3-hydroxybutyrate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011294">
        <property type="entry name" value="3-OHbutyrate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01963">
        <property type="entry name" value="PHB_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAV99155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD64184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDW61513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000183696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000218824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="261" mass="27216" checksum="581930C309393427" modified="2016-02-17" version="1">MSSIQGKVAVVTGAASGIGKEIAFELSRAGAAIAIADLNQAGAQAVADEIAAAGGRAIGVAMDVTDEAAVNAGIEQVVAQLGGIDILVSNAGIQIVNPIENYAFADWKKMLAIHLDGAFLTTKAALPHMYKGDKGGVVIYMGSVHSHEASPLKSAYVTAKHGLLGLSRVLAKEGAKHNVRSHVVCPGFVRTPLVDKQIPEQAKELGISEDEVIKKVMLGNTVDGVFTTVQDVAQTVRFLAEFPSAALTGQSFVVSHGWYMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDP5</accession>
    <name>A0A0S2DDP5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1252</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56609">
        <property type="protein sequence ID" value="ALN56609"/>
        <property type="gene ID" value="GLE_1252"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1252"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1236"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="145" mass="16529" checksum="E4A8F2D511782489" modified="2016-02-17" version="1">MASCKTIEPANSTLKDMQEWATPEPLDRVSPANEQRRAKAEMVRWVEQYLKHEYRVIDQRFVLTAPGSTDGAAIGSKAHQFVTQKLGGGVRISGWFDDDNYRFLLWTFGNGAPRYVIFVLTRDFLPGTDERRMVGYLELELAAKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDU0</accession>
    <name>A0A0S2DDU0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56477">
        <property type="protein sequence ID" value="ALN56477"/>
        <property type="gene ID" value="GLE_1119"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1119"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1105"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="73" mass="7625" checksum="7C42107198DB9430" modified="2016-02-17" version="1">MLGDFGHGNGAPGARRVGRRGQRLYLPAGPALRALRLLPVGATRVATATSGGRRELGAPRSRLASLLQRPRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE69</accession>
    <name>A0A0S2DE69_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">5'-nucleotidase SurE</fullName>
            <ecNumber evidence="5">3.1.3.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Nucleoside 5'-monophosphate phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">surE</name>
        <name evidence="8" type="ORF">BV903_21705</name>
        <name evidence="9" type="ORF">FE772_07850</name>
        <name evidence="7" type="ORF">GLE_1496</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate</text>
            <dbReference type="Rhea" id="RHEA:12484"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18254"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
            <dbReference type="EC" id="3.1.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="5">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the SurE nucleotidase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.5" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000072">
        <property type="protein sequence ID" value="OPD61794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946823.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000072.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1496"/>
    <dbReference type="EnsemblBacteria" id="ALN56853">
        <property type="protein sequence ID" value="ALN56853"/>
        <property type="gene ID" value="GLE_1496"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61794">
        <property type="protein sequence ID" value="OPD61794"/>
        <property type="gene ID" value="BV903_21705"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1496"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1477"/>
    <dbReference type="OMA" id="DCVHIAL"/>
    <dbReference type="OrthoDB" id="1909278at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106411">
        <property type="term" value="F:XMP 5'-nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00060">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030048">
        <property type="entry name" value="SurE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002828">
        <property type="entry name" value="SurE-like_Pase/nucleotidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036523">
        <property type="entry name" value="SurE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30457">
        <property type="entry name" value="PTHR30457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01975">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64167">
        <property type="entry name" value="SSF64167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00087">
        <property type="entry name" value="surE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SurE" evidence="6">
        <location>
            <begin position="3"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN56853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD61794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW25591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="264" mass="28085" checksum="B6F1BA057D340A88" modified="2016-02-17" version="1">MRVLVSNDDGVDAPGIRILAQGLREAGHEVLVVAPDRDRSGASNSLTLDMPVRVARLDETTWRVYGTPTDCVHVALAGMLELEPDIVVSGINTTANMGDDVIYSGTVAAAMEGRFLGLPAVAMSLAAADHDGRHYETAARAAVEIIARLRTDPLPADTILNVNVPDLAWDEVAGFEVTRLGNRHRAEACIPQRDPRGRQWWWIGPAGAEADAGAGTDFHAVRTGNISITPIHVDLTRYQALEQVASWVGGLAASLDAPKAESAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEC9</accession>
    <name>A0A0S2DEC9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1312</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56669">
        <property type="protein sequence ID" value="ALN56669"/>
        <property type="gene ID" value="GLE_1312"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1312"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1296"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046116">
        <property type="entry name" value="DUF6053"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19523">
        <property type="entry name" value="DUF6053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="94" mass="9741" checksum="7A0D0FE64D752300" modified="2016-02-17" version="1">MRASVGGRAGSDNPQNQAFIGFSYERAELRRASSRGATGDRLSPRRNVAEPAALAAFVGGASAPMLFALIAAIWNKSIGVEAPPTKAVLMGPIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DED6</accession>
    <name>A0A0S2DED6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YkgJ family cysteine cluster protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Zinc/iron-chelating domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_07020</name>
        <name evidence="3" type="ORF">FE772_08510</name>
        <name evidence="1" type="ORF">GLE_1641</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000013">
        <property type="protein sequence ID" value="OPD64635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946938.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000013.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56998">
        <property type="protein sequence ID" value="ALN56998"/>
        <property type="gene ID" value="GLE_1641"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64635">
        <property type="protein sequence ID" value="OPD64635"/>
        <property type="gene ID" value="BV903_07020"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1641"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1620"/>
    <dbReference type="OMA" id="ECVPGCH"/>
    <dbReference type="OrthoDB" id="1677662at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005358">
        <property type="entry name" value="Puta_zinc/iron-chelating_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03692">
        <property type="entry name" value="CxxCxxCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD64635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="117" mass="12835" checksum="06CCA0A2C900233A" modified="2016-02-17" version="1">MTRDDPELTALRARIPAFGCRAGCHDCCGPVTASAQEMARLPFKPEAERDAALAAWSCPHLGPHGCEAYEERPLICRLFGTTPRLRCPNGCGPETMIDEAAENAVHAYLRRTRQVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DED8</accession>
    <name>A0A0S2DED8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA dimethylallyltransferase</fullName>
            <ecNumber evidence="5">2.5.1.75</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Dimethylallyl diphosphate:tRNA dimethylallyltransferase</fullName>
            <shortName evidence="5">DMAPP:tRNA dimethylallyltransferase</shortName>
            <shortName evidence="5">DMATase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Isopentenyl-diphosphate:tRNA isopentenyltransferase</fullName>
            <shortName evidence="5">IPP transferase</shortName>
            <shortName evidence="5">IPPT</shortName>
            <shortName evidence="5">IPTase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 10" type="primary">miaA</name>
        <name evidence="10" type="ORF">GLE_1509</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5 7">Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5 6">
            <text>adenosine(37) in tRNA + dimethylallyl diphosphate = diphosphate + N(6)-dimethylallyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:26482"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10375"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74415"/>
            <dbReference type="EC" id="2.5.1.75"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5 8">Belongs to the IPP transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.75" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1509"/>
    <dbReference type="EnsemblBacteria" id="ALN56866">
        <property type="protein sequence ID" value="ALN56866"/>
        <property type="gene ID" value="GLE_1509"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1509"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1490"/>
    <dbReference type="OMA" id="YAKRQYT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052381">
        <property type="term" value="F:tRNA dimethylallyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00185">
        <property type="entry name" value="IPP_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039657">
        <property type="entry name" value="Dimethylallyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018022">
        <property type="entry name" value="IPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11088">
        <property type="entry name" value="PTHR11088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00174">
        <property type="entry name" value="miaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 6" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="81"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <begin position="104"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <begin position="228"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="79"/>
            <end position="86"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN56866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="392" mass="42894" checksum="CD807627F1FC61F9" modified="2016-02-17" version="1">MQIPVEPPPARGRAAAPNARRSGVAQRPRPIAAVALRRRAGFRGPRGCARLRVAHRRAIRRPRMTASHDPRPLAIALMGPTASGKTALALDWAARLDAEIVSVDSALVYRGLDIGAAKPSAAERAAVPHHLIDVREPWQAYSAAEFASDARAAMDQIAARGRLPILAGGTGLYFHALLHGLSDMPEADPATRAALAEEAARRGWAALHAELAALDPQAAARIHATDAQRIQRALEVWRLSGRTISDWRLASAARPRLPFRVLKLVLAPAERAVLHARIERRFEQMLADGFLDEVRALRALPGLAAHPSPLELPAIRAVGYRQAWEHLDGAFDAAQLRDRGIFATRQLAKRQLTWLRGELDARWFDPLRDAAELEHALRLFAGARLRAPRQGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEM7</accession>
    <name>A0A0S2DEM7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1744</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57099">
        <property type="protein sequence ID" value="ALN57099"/>
        <property type="gene ID" value="GLE_1744"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1744"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1720"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="50" mass="5726" checksum="9322BB1BBDAE6F5D" modified="2016-02-17" version="1">MSEGRRWWNGAGRRALWPDPEKRWRALVGGPSGPTALRSIRGDPQQKRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEU5</accession>
    <name>A0A0S2DEU5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1737</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947016.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1737"/>
    <dbReference type="EnsemblBacteria" id="ALN57092">
        <property type="protein sequence ID" value="ALN57092"/>
        <property type="gene ID" value="GLE_1737"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1737"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1714"/>
    <dbReference type="OMA" id="TKQEYNA"/>
    <dbReference type="OrthoDB" id="2076741at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="467" mass="47162" checksum="94B96DE693065654" modified="2016-02-17" version="1">MNRRPDAPDPLSPEERDLAERLLRLGPHDGPSAALDAAILAAARAAVAAEPVPDAASQAAAALAAAPLAAAPQAAAPQAAAPQAAAPQAAPARPTAPQTGAPRARPNKTRWPAWIGVAASLTLAVGVAWQLRPLDKAPSALSEEQAAPAVAAMPQAEAGADAAANAAADAAIAVPEMPAAAAQAPALPDLPASAPAQRAPAADVLAAPQPPEPMPIEDLPPAPVLAKPAPAPARAESPPVEDRALESRAAASKAVENHAAEKRAAADAAPPAARELDRRAKSEAPRAAQAQSTQAMPAPADAPPPPAPPPPPAPAPAIAPPAAQGYGYSAPAAAAPAGAARARGQPAAESKRAAGQVEGLSRREAERPVAAPPAEAAANAPIAAEAQRAAPPQQNAADATVLERVQITGSRIGPSQHANALAPEQWLERIRQYRDDGELDLARQDLREFRRAHPRARIPKDLRSLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEV6</accession>
    <name>A0A0S2DEV6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-hydroxyacyl-CoA dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">fadJ</name>
        <name evidence="14" type="ORF">FE772_08805</name>
        <name evidence="13" type="ORF">GLE_1702</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">C3</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:22432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57318"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="1.1.1.35"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.35" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946988.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1702"/>
    <dbReference type="EnsemblBacteria" id="ALN57057">
        <property type="protein sequence ID" value="ALN57057"/>
        <property type="gene ID" value="GLE_1702"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1702"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1680"/>
    <dbReference type="OMA" id="GYGWPVY"/>
    <dbReference type="OrthoDB" id="977512at2"/>
    <dbReference type="UniPathway" id="UPA00659"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003857">
        <property type="term" value="F:3-hydroxyacyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3HCDH_N" evidence="12">
        <location>
            <begin position="318"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="11">
        <location>
            <begin position="495"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN57057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW25752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="689" mass="74231" checksum="B2B15DA73420DBA5" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEX2</accession>
    <name>A0A0S2DEX2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycine dehydrogenase (decarboxylating)</fullName>
            <ecNumber evidence="7">1.4.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glycine cleavage system P-protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glycine decarboxylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glycine dehydrogenase (aminomethyl-transferring)</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">gcvP</name>
        <name evidence="10" type="ORF">FE772_08095</name>
        <name evidence="9" type="ORF">GLE_1547</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>(R)-N(6)-lipoyl-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[glycine-cleavage complex H protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:24304"/>
            <dbReference type="Rhea" id="RHEA-COMP:10494"/>
            <dbReference type="Rhea" id="RHEA-COMP:10495"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="1.4.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 7">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the GcvP family.</text>
    </comment>
    <dbReference type="EC" id="1.4.4.2" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946867.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1547"/>
    <dbReference type="EnsemblBacteria" id="ALN56904">
        <property type="protein sequence ID" value="ALN56904"/>
        <property type="gene ID" value="GLE_1547"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1547"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1529"/>
    <dbReference type="OMA" id="CVPMSEY"/>
    <dbReference type="OrthoDB" id="70707at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004375">
        <property type="term" value="F:glycine dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00613">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00711">
        <property type="entry name" value="GcvP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003437">
        <property type="entry name" value="GcvP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020581">
        <property type="entry name" value="GDC_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11773">
        <property type="entry name" value="PTHR11773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02347">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00461">
        <property type="entry name" value="gcvP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7 8">
        <location>
            <position position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR603437-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW25634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="953" mass="103136" checksum="22D0A7849A82AA97" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF91</accession>
    <name>A0A0S2DF91_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Methylcrotonoyl-CoA carboxylase</fullName>
            <ecNumber evidence="5">6.4.1.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_10005</name>
        <name evidence="5" type="ORF">GLE_1967</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.4.1.4" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947177.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1967"/>
    <dbReference type="EnsemblBacteria" id="ALN57318">
        <property type="protein sequence ID" value="ALN57318"/>
        <property type="gene ID" value="GLE_1967"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1967"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1932"/>
    <dbReference type="OMA" id="AYLPIMS"/>
    <dbReference type="OrthoDB" id="123223at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004485">
        <property type="term" value="F:methylcrotonoyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="22"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="4">
        <location>
            <begin position="278"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW25949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="536" mass="57772" checksum="1C857D355B67315A" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFB8</accession>
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        <submittedName>
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        </submittedName>
    </protein>
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    </gene>
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    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN57257">
        <property type="protein sequence ID" value="ALN57257"/>
        <property type="gene ID" value="GLE_1906"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1906"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1874"/>
    <dbReference type="OMA" id="WIDGQAR"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="197" mass="21708" checksum="789970F5F423934A" modified="2016-02-17" version="1">MSAKPTGPADDLPVIAFDDAAAFERWLETPPAKRGLWLKIAKKGKGAVTVDYAQALDVALCHGWIDGQKRSLDEVYFLQRFVPRRPRSLWSQINIGKCEALIAQGRMRPGGQREIDAARADGRWAAAYASSSKIEVPQDLAAALAKSPKAREFFEGLDAGNRYAVLWRVHTAKKAETRAARIAKLVEMLGRGEKIHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFD4</accession>
    <name>A0A0S2DFD4_LYSEN</name>
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        </submittedName>
        <submittedName>
            <fullName evidence="3">Long-chain fatty acid--CoA ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_09485</name>
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    <organism evidence="2 4">
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            <taxon>Proteobacteria</taxon>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
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    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ALN57203">
        <property type="protein sequence ID" value="ALN57203"/>
        <property type="gene ID" value="GLE_1851"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1851"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1822"/>
    <dbReference type="OMA" id="MSRFTET"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="AMP-dep_Synth/Lig"/>
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        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="27"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="562" mass="58805" checksum="EE06CB2155419D96" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFQ5</accession>
    <name>A0A0S2DFQ5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_09830</name>
        <name evidence="2" type="ORF">GLE_1932</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW25919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57283">
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        <property type="gene ID" value="GLE_1932"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1932"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1898"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="337" mass="37541" checksum="0D58162810DFCC60" modified="2016-02-17" version="1">MLTHLRRLFRSSAAQAPAPAVSTPPPDIHMHWFGDTRRPIPDWERIAVAERPDWSIAESDAFWTAAAEHWLRALAESLGSGYRVQSSERFLLLTAMPPAQAQAYLKFCETARRRIVRNLGPLAQPVGGGKHVCLVFIEDDAYYDYIAHYYPEGGEYAMSAGVFLNAGYGHFALCESHADAMQPTIAHELTHALLAHLPIPTWLNEGMAVNTEHSLFPHLAHPSAQLYTPDEIERKHIKFWTAERIQEFWSGAAFHRTDDGSLLSYDLAKKMVALAAHDHAAFVPFVLAAHRDDGGAKAAERLEYPVENLVEAVLGEGDWEPRPQGWRGPAQPAREAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG84</accession>
    <name>A0A0S2DG84_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADH-quinone oxidoreductase subunit E</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">NADH dehydrogenase I subunit E</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">NDH-1 subunit E</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">nuoE</name>
        <name evidence="11" type="ORF">FE772_10915</name>
        <name evidence="10" type="ORF">GLE_2163</name>
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    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="9">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 24 kDa subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW26106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947329.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2163"/>
    <dbReference type="EnsemblBacteria" id="ALN57513">
        <property type="protein sequence ID" value="ALN57513"/>
        <property type="gene ID" value="GLE_2163"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2163"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2126"/>
    <dbReference type="OMA" id="MYDTKPV"/>
    <dbReference type="OrthoDB" id="1206880at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03064">
        <property type="entry name" value="TRX_Fd_NuoE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002023">
        <property type="entry name" value="NuoE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042128">
        <property type="entry name" value="NuoE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041921">
        <property type="entry name" value="NuoE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
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</entry>
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            <authorList>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Feng T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </location>
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    <evidence type="ECO:0000256" key="1">
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
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    </evidence>
    <sequence length="69" mass="7309" checksum="CC52CEC654B7CDC7" modified="2016-02-17" version="1">MKSRHTLLAALAAFAFSASAIAVAAPPFNPCQQCRDAYQRCMNNGGLDGTRDCETPFSQCLLSAGCPLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGJ7</accession>
    <name>A0A0S2DGJ7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2308</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57657">
        <property type="protein sequence ID" value="ALN57657"/>
        <property type="gene ID" value="GLE_2308"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2308"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2273"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="51" mass="5251" checksum="36A95908795283CE" modified="2016-02-17" version="1">MDAFAGAMVAAAMCVVRIAPRCAGESPALAWKTRDDACASRHGGCVVATRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGQ0</accession>
    <name>A0A0S2DGQ0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Chaperone protein DnaK</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">HSP70</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Heat shock 70 kDa protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Heat shock protein 70</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">dnaK</name>
        <name evidence="11" type="ORF">FE772_11250</name>
        <name evidence="10" type="ORF">GLE_2232</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts as a chaperone.</text>
    </comment>
    <comment type="induction">
        <text evidence="7">By stress conditions e.g. heat shock.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947384.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2232"/>
    <dbReference type="EnsemblBacteria" id="ALN57581">
        <property type="protein sequence ID" value="ALN57581"/>
        <property type="gene ID" value="GLE_2232"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2232"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2197"/>
    <dbReference type="OMA" id="ISIKRHM"/>
    <dbReference type="OrthoDB" id="161217at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00332">
        <property type="entry name" value="DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012725">
        <property type="entry name" value="Chaperone_DnaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="SSF100920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02350">
        <property type="entry name" value="prok_dnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="5 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="579"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphothreonine; by autocatalysis" evidence="7">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN57581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW26160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="639" mass="68137" checksum="E082FF7B5C096EE6" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGY2</accession>
    <name>A0A0S2DGY2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Leucyl/phenylalanyl-tRNA--protein transferase</fullName>
            <ecNumber evidence="4">2.3.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">L/F-transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Leucyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Phenyalanyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">aat</name>
        <name evidence="6" type="ORF">GLE_2312</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein] = H(+) + N-terminal L-leucyl-L-arginyl-[protein] + tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:50416"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="Rhea" id="RHEA-COMP:12672"/>
            <dbReference type="Rhea" id="RHEA-COMP:12673"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64719"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:133044"/>
            <dbReference type="EC" id="2.3.2.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-leucyl-tRNA(Leu) + N-terminal L-lysyl-[protein] = H(+) + N-terminal L-leucyl-L-lysyl-[protein] + tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:12340"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="Rhea" id="RHEA-COMP:12670"/>
            <dbReference type="Rhea" id="RHEA-COMP:12671"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:65249"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:133043"/>
            <dbReference type="EC" id="2.3.2.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an N-terminal L-alpha-aminoacyl-[protein] + L-phenylalanyl-tRNA(Phe) = an N-terminal L-phenylalanyl-L-alpha-aminoacyl-[protein] + tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:43632"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="Rhea" id="RHEA-COMP:10636"/>
            <dbReference type="Rhea" id="RHEA-COMP:10637"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:78597"/>
            <dbReference type="ChEBI" id="CHEBI:83561"/>
            <dbReference type="EC" id="2.3.2.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the L/F-transferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.6" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947441.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2312"/>
    <dbReference type="EnsemblBacteria" id="ALN57661">
        <property type="protein sequence ID" value="ALN57661"/>
        <property type="gene ID" value="GLE_2312"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2312"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2277"/>
    <dbReference type="OMA" id="YRQGIFP"/>
    <dbReference type="OrthoDB" id="1670846at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008914">
        <property type="term" value="F:leucyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3550">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00688">
        <property type="entry name" value="Leu_Phe_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004616">
        <property type="entry name" value="Leu/Phe-tRNA_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042203">
        <property type="entry name" value="Leu/Phe-tRNA_Trfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042221">
        <property type="entry name" value="Leu/Phe-tRNA_Trfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30098">
        <property type="entry name" value="PTHR30098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03588">
        <property type="entry name" value="Leu_Phe_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00667">
        <property type="entry name" value="aat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="252" mass="27016" checksum="5BC8F7E4E34C4B8E" modified="2016-02-17" version="1">MKRLPFLLPSDPEAPFPPGDRALSEPDGLLAVGGDLGPARLLNAYRSGVFPWPSEGYPLLWWCPDPRTVFRTDGVRLASKFRRGLRRSAWTVRADTAFEAVIGACAAAPRPGQDGTWIVPEMIEAYTRMHRLGHAHSVEVFDGEALVGGIYGIAIGRMFYGESMFSAVSGGSKAALAALARRLHGWGWPLLDAQVENPHLASLGAEAMPRARFLERAGELAALPGFEPGPWTGRFGTMAAAELAESLPAPGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGY7</accession>
    <name>A0A0S2DGY7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chemotaxis protein CheW</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2 4">Purine-binding Chemotaxis protein CheW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cheW</name>
        <name evidence="3" type="ORF">BV903_01340</name>
        <name evidence="4" type="ORF">FE772_12260</name>
        <name evidence="2" type="ORF">GLE_2452</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000003">
        <property type="protein sequence ID" value="OPD65673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947548.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2452"/>
    <dbReference type="EnsemblBacteria" id="ALN57801">
        <property type="protein sequence ID" value="ALN57801"/>
        <property type="gene ID" value="GLE_2452"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65673">
        <property type="protein sequence ID" value="OPD65673"/>
        <property type="gene ID" value="BV903_01340"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2452"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2415"/>
    <dbReference type="OMA" id="IAQAPAW"/>
    <dbReference type="OrthoDB" id="1711729at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039315">
        <property type="entry name" value="CheW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22617">
        <property type="entry name" value="PTHR22617"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheW-like" evidence="1">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD65673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="153" mass="16942" checksum="D83B0CC524136723" modified="2016-02-17" version="1">MLFLVFQLDAERYAIDAATVTAVLPQVELRRLPQAHPAVAGVFDYRGEVVPLIDLCRLALARPARAAMSTRIVLADYRDRAGQARRLGLLAERVLDTVRLEPQAFAPSGVDQPQARYLGPVARDPHGLLQWIGVRELLPDDVHDLLFQQAAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGZ5</accession>
    <name>A0A0S2DGZ5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57624">
        <property type="protein sequence ID" value="ALN57624"/>
        <property type="gene ID" value="GLE_2275"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2275"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2240"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="110" mass="11301" checksum="03147CDA4A963191" modified="2016-02-17" version="1">MAACRSXXXXXXXGRSSRAAAARRRAAARAAVGCAAARQGAVAARAAPTRAAGRAGPRGLLESPVHPHTHTPGHDRTQSRPPANRRPQGPAGFAQGVSLTTTPKSSAWKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH34</accession>
    <name>A0A0S2DH34_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type VI secretion protein, VC_A0107 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Type VI secretion system contractile sheath small subunit</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Type VI secretion system-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tssB</name>
        <name evidence="2" type="ORF">BV903_00055</name>
        <name evidence="3" type="ORF">FE772_12905</name>
        <name evidence="1" type="ORF">GLE_2572</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000001">
        <property type="protein sequence ID" value="OPD65944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947645.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2572"/>
    <dbReference type="EnsemblBacteria" id="ALN57921">
        <property type="protein sequence ID" value="ALN57921"/>
        <property type="gene ID" value="GLE_2572"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65944">
        <property type="protein sequence ID" value="OPD65944"/>
        <property type="gene ID" value="BV903_00055"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2572"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2531"/>
    <dbReference type="OMA" id="ANLDTYM"/>
    <dbReference type="OrthoDB" id="1278805at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008312">
        <property type="entry name" value="T6SS_TssB1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35850">
        <property type="entry name" value="PTHR35850"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05591">
        <property type="entry name" value="T6SS_VipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028301">
        <property type="entry name" value="UCP028301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03358">
        <property type="entry name" value="VI_chp_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD65944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="167" mass="18610" checksum="FF4D91DC884F6DC6" modified="2016-02-17" version="1">MSVQNSQKFIARNRAPRVQIEYDVEIYGAQKKVQVPFVMGVLSDLSGANSVDLPPIEERKALEIDVDNFDSRMRAMKPRVQISVPNTLTGEGELAVDLTFERLEDFSPAEVVKRIEPMAKLLEARTQLSNLSTYLDGKAGAERLIADTIRDPALLRALASTPNPERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIJ5</accession>
    <name>A0A0S2DIJ5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LysR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_14880</name>
        <name evidence="4" type="ORF">GLE_2975</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2975"/>
    <dbReference type="EnsemblBacteria" id="ALN58323">
        <property type="protein sequence ID" value="ALN58323"/>
        <property type="gene ID" value="GLE_2975"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2975"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2936"/>
    <dbReference type="OMA" id="PRYVADD"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="311"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="340" mass="37524" checksum="C61E1B5CE81BD080" modified="2016-02-17" version="1">MHDLNDLYYFAMVVDHAGFAAAERALGIPKSRLSRRISQLETDLGVRLLQRSTRRFAVTEVGNSVYRHAQSMLAEAQAAREVVDRLSAEPRGVIRVSVPVGLAQQQIPKLLPEFLAKYPQVRVQLNVSNRRVDIINEGVDVALRVRSKLDDDGSLVMRSFGQIQELLVASPKYLNRMGRPSNPDELAEHVTLSISEDDARQRWELHGPDGEVRKVELKPRVMGFDFPMLMALAEQGVGITLLPETVCAEAVRRGELEVVLPNWRLPQGIFHAVFASRRGLLPAVRVFIDFLAEKAPSLVESARLQCSDIKGGQPCPDSVAARDAKAGKKTDKGAGVPAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIK5</accession>
    <name>A0A0S2DIK5_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3106</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
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            <end position="77"/>
        </location>
    </feature>
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        <location>
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            <end position="542"/>
        </location>
    </feature>
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            <begin position="1"/>
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        </location>
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            <end position="472"/>
        </location>
    </feature>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN58453.1"/>
        </source>
    </evidence>
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        </source>
    </evidence>
    <sequence length="542" mass="53526" checksum="13F4A7E65FFDAC41" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58322.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
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</entry>
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    <accession>A0A0S2DIQ1</accession>
    <name>A0A0S2DIQ1_LYSEN</name>
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            <authorList>
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    <reference evidence="5 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
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                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">OH11</strain>
        </source>
    </reference>
    <reference evidence="6 11" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 11">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
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        </subcellularLocation>
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    </dbReference>
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    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58410">
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        <property type="gene ID" value="GLE_3063"/>
    </dbReference>
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        <property type="gene ID" value="BV903_14685"/>
    </dbReference>
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    <dbReference type="OMA" id="GPCANKV"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="CSD"/>
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        <property type="entry name" value="CSP_DNA-bd"/>
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    </dbReference>
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    </evidence>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="69" mass="7624" checksum="AAFFEBCBF20F2E2C" modified="2016-02-17" version="1">MSGKEIGTVKWFNDAKGFGFISRENGEDVFVHFRAIQSQGFKSLKEGQKVSFTVVQGQKGLQADAVEPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIQ6</accession>
    <name>A0A0S2DIQ6_LYSEN</name>
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    </gene>
    <organism evidence="7 8">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="MFS_dom"/>
    </dbReference>
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        <property type="entry name" value="MFS_trans_sf"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <proteinExistence type="predicted"/>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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        </location>
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            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="305"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="360"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="461"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="14"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="496" mass="49885" checksum="33A4290F1A4B8528" modified="2016-02-17" version="1">MPAPSPALAGHSRLLTGLLLALFLGALEQTIVATALPAIVRDLAGFDLLGWALSAYLLATAAATPVIGKLSDLHGRRALLRACMALFALGSAICALAPDMRTLIGGRAVQGIGGAGLIVVAQAAVAQLAGPAQRSRYAGYFALVWAAAGLIGPLLGGALSDWLHWRAIFWINLPLGALVLWIGAPGLRALGPGHGEGRIDLAATALFAVATGAFLLALSWGGARHPWLSAPVLAALAVALATGAVFFARQRRSADPLLAPAWLRDPAIGPALAASLLLYGFYIAVAVLMPAYWQLGHGLRSTVSGALLVPALIAGAAGALIGGRAAARSGDYKRPVLPGLAIAALTLTLMGALASQLSAWSVSALLALVAFGIGPCTATVNAVAQNAAPARQLGALTGAMALSRTLGTAVVVAAGSAMIVAHVRLGGGALAGGLLAGGESAAAQTLPETTRALLRDAYAELFFFAAAGIALALLCYAWIRPRTAHAAELAEPAPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIR2</accession>
    <name>A0A0S2DIR2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Redoxin domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_3079</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3079"/>
    <dbReference type="EnsemblBacteria" id="ALN58426">
        <property type="protein sequence ID" value="ALN58426"/>
        <property type="gene ID" value="GLE_3079"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3079"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3038"/>
    <dbReference type="OMA" id="IPHMVII"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015036">
        <property type="term" value="F:disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="36"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="185" mass="20116" checksum="FE947DCA222434FE" modified="2016-02-17" version="1">MALACAGVYSSTSAQTPAPAATPAAAQPARAASAAPALGDPAPDFLGLDRSGRPVKVSDYRGKPVVISFWAGWCAPCRRELPMLSTLQRSVGREHLQVIAVNLNEPRHDYEEFLRLNPDLDLDFIRDPGSAARYYGVRTVPNLFVVDRDGKLVQAHRGYSQEKIEQFVRELAPLLPPRAARKPGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIR7</accession>
    <name>A0A0S2DIR7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3037</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58384">
        <property type="protein sequence ID" value="ALN58384"/>
        <property type="gene ID" value="GLE_3037"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3037"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2997"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="44" mass="4553" checksum="E91635446B323DB1" modified="2016-02-17" version="1">MPRRSRDPTVGAALAATAPTQPRRMPGCERGILVRADAVPAAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIT4</accession>
    <name>A0A0S2DIT4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2953</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947936.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2953"/>
    <dbReference type="EnsemblBacteria" id="ALN58301">
        <property type="protein sequence ID" value="ALN58301"/>
        <property type="gene ID" value="GLE_2953"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2953"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2915"/>
    <dbReference type="OMA" id="PNAWDHA"/>
    <dbReference type="OrthoDB" id="1485205at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016833">
        <property type="term" value="F:oxo-acid-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00377">
        <property type="entry name" value="ICL_PEPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039556">
        <property type="entry name" value="ICL/PEPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="275" mass="28982" checksum="8651DAF48BA582E4" modified="2016-02-17" version="1">MTPQSERADRFRRLHHDDPQRPGPLLLANAWDAGSARLIESLGAPAVATTSAGVAWAHGFADGDHLPVPRLVATVADIVRAVRVPLSVDVEGGYSDDPDTVADHVAGLVEVGAVGINIEDGGGAPELLCAKIERIRQATATLGVALFVNARTDVYLRGLVPEAQRVDETLARAARYREAGADGLFVPGLTDETQVRAIAAGAGLPLNLLARAALPPAPQLREWGVRRLSAGSDLAQSAHARVRALAADFLRDGDSRPLSAQALPYSELNALFSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIT5</accession>
    <name>A0A0S2DIT5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycerophosphoryl diester phosphodiesterase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3097</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948039.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3097"/>
    <dbReference type="EnsemblBacteria" id="ALN58444">
        <property type="protein sequence ID" value="ALN58444"/>
        <property type="gene ID" value="GLE_3097"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3097"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3055"/>
    <dbReference type="OMA" id="RCTIYFL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="SSF51695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595258" evidence="1">
        <location>
            <begin position="26"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="GP-PDE" evidence="2">
        <location>
            <begin position="50"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="437" mass="47263" checksum="D86E8835268A78D3" modified="2016-02-17" version="1">MPHPNLPRRPLAALALLLFAAAAGAAAPERKPSMPHASPPTSAAPGQQGLIVIAHRGASGYRPEHTLEAYRLAIAQGADFIEPDLVATRDGELVVRHENEISGTTDVAAHPEFADRKTTKTIDGESLTGWFTEDFTLAELKTLRAKERIPQVRPGNTRYDGQFPIATLKEVIALAKQESRDGRVVGIYPETKHPTWFASEGRHLDGSPIGISLGQKLVDTLVAEGFTDPRRIYIQSFEVGNLIELKQRILPKAGIDLPLVQLYGDFERDTPYDIVYNRRSGADLARIYGDLAQAIPGGLAAARYGALTEPAALRWMQAHYASGLGPYKASLIERAPLPAKRDADGDGHALLATRNTGIVHPVLARALALGLQVHPYTVRAEEPFLTQTANGIDQSALGEALQLYGLGVQGFFIDNPDIGVAARNLFLEQSKIAPIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ27</accession>
    <name>A0A0S2DJ27_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Potassium-transporting ATPase KdpC subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP phosphohydrolase [potassium-transporting] C chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Potassium-binding and translocating subunit C</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Potassium-translocating ATPase C chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 13" type="primary">kdpC</name>
        <name evidence="13" type="ORF">GLE_3194</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">The system is composed of three essential subunits: KdpA, KdpB and KdpC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
            <topology evidence="11">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the KdpC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3194"/>
    <dbReference type="EnsemblBacteria" id="ALN58540">
        <property type="protein sequence ID" value="ALN58540"/>
        <property type="gene ID" value="GLE_3194"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3194"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3149"/>
    <dbReference type="OMA" id="KYFWPRP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008556">
        <property type="term" value="F:P-type potassium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00276">
        <property type="entry name" value="KdpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003820">
        <property type="entry name" value="KdpC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30042">
        <property type="entry name" value="PTHR30042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02669">
        <property type="entry name" value="KdpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001296">
        <property type="entry name" value="K_ATPase_KdpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00681">
        <property type="entry name" value="kdpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 11" id="KW-0630">Potassium</keyword>
    <keyword evidence="3 11" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="22"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN58540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="199" mass="20724" checksum="B146EE225EA2A2EF" modified="2016-02-17" version="1">MNTQPTCAASIDDRQSLRAPSLYAVVCLLGFGLAYSLAGTAIGRVAFPAQATGSILERDGRAVGSELVAQPFADARYFQPRPSAAKYDPMAASGSNQARSNPDLRKRLAEETAAIAQREGIAESEVPAELATQSGGGLDPHISPRSAQVQAARVAQARGLDADRVAALIASNTEAPQFGALGEPRVNVLKLNLALDAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJP4</accession>
    <name>A0A0S2DJP4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3149</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3149"/>
    <dbReference type="EnsemblBacteria" id="ALN58495">
        <property type="protein sequence ID" value="ALN58495"/>
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    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3149"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3106"/>
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    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="54" mass="5903" checksum="DD3EB1FA142B4156" modified="2016-02-17" version="1">MKSHVVGALILIVIGTLFLLNNLGFTNLSVTKLLVTWWPAILIAVGLGLLFKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJP7</accession>
    <name>A0A0S2DJP7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3158</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58504">
        <property type="protein sequence ID" value="ALN58504"/>
        <property type="gene ID" value="GLE_3158"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3158"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="50" mass="5698" checksum="CC580D2DC9E8EB38" modified="2016-02-17" version="1">MQAERIGYCHGVSPSWKVMRERGRCRVDLRVLVAFPGFNGSFTKLNLTRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJW4</accession>
    <name>A0A0S2DJW4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Oxidoreductase, short chain dehydrogenase/reductase family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">SDR family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_17115</name>
        <name evidence="1" type="ORF">GLE_3474</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948319.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3474"/>
    <dbReference type="EnsemblBacteria" id="ALN58819">
        <property type="protein sequence ID" value="ALN58819"/>
        <property type="gene ID" value="GLE_3474"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3474"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3421"/>
    <dbReference type="OMA" id="ERVEFHK"/>
    <dbReference type="OrthoDB" id="1821409at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="257" mass="27026" checksum="78E52A7B1C360613" modified="2016-02-17" version="1">MPDRSLTGKHLVIGGGAKNLGGLISRELAQAGAAGIAVHYNSDATRAAAEETVAAVKAAGADAFAHQGDLTRPAEVAKLFDAAKAKFGKLDIAINTTGMVIKKPLVEVTEAEYDTMFAVNSKAAFFFIQEAGKKLADDGNICTIVSSLLAAYTPFYAVYPGSKAPIEHFTRAASKEFGERGISVNAVGPGPMDTPFFYPAESKESAAYHATAAALSNRTKSGLTEIQDIAPLVKFLVTDGWWITGQTIFANGGYTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJX3</accession>
    <name>A0A0S2DJX3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_17685</name>
        <name evidence="2" type="ORF">GLE_3589</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948400.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58933">
        <property type="protein sequence ID" value="ALN58933"/>
        <property type="gene ID" value="GLE_3589"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3589"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3533"/>
    <dbReference type="OMA" id="WYTPNPW"/>
    <dbReference type="OrthoDB" id="1801225at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="176" mass="18823" checksum="3565AB3FE1A5A4BF" modified="2016-02-17" version="1">MASPIAATAPYWVPALSMLMIYRRVRRNFGVQPWRPVRSGIRLGVLVLVAAMLCALGAFQPSLALALGLGIGATLGALLGLLALKHTHVAWRDDQRTYTPNPWIGGALTALLVGRIAWRYTHEGFAATQAPSALTMGMATVLIGYSLAYVIGLMVQMRRLAAERAATSASTPPVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK09</accession>
    <name>A0A0S2DK09_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Translocator protein, LysE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_3432</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58777">
        <property type="protein sequence ID" value="ALN58777"/>
        <property type="gene ID" value="GLE_3432"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3432"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3382"/>
    <dbReference type="OMA" id="LHMACCA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006324">
        <property type="entry name" value="LeuE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="236" mass="24213" checksum="AF3A2A3423703ED9" modified="2016-02-17" version="1">MAVPANNSDKRAIRATPCRRTGPIMAGMDLPTALLFCATVFPLICTPGPDMLFVASQSLGGGAAAGLRATAGVCAGYLLHSLLAALGLAALVAASPPLFQALRWIGVAYLAWLAFKLLRSALRRGALDVQAFERGGRRDALRRGFLTAALNPKGMMIYLAILPQFMRADAPAAPQAVALSALFVSGCALVYAALSLALGRGARGGGATTLGGRRRRWIDGVAGGLIAAAAGKLALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK81</accession>
    <name>A0A0S2DK81_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein translocase subunit SecD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 11" type="primary">secD</name>
        <name evidence="12" type="ORF">BV903_21580</name>
        <name evidence="13" type="ORF">FE772_17295</name>
        <name evidence="11" type="ORF">GLE_3513</name>
    </gene>
    <organism evidence="11 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">C3</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">B25</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SecD/SecF family. SecD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000071">
        <property type="protein sequence ID" value="OPD61869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948346.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000071.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3513"/>
    <dbReference type="EnsemblBacteria" id="ALN58857">
        <property type="protein sequence ID" value="ALN58857"/>
        <property type="gene ID" value="GLE_3513"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61869">
        <property type="protein sequence ID" value="OPD61869"/>
        <property type="gene ID" value="BV903_21580"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3513"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3457"/>
    <dbReference type="OMA" id="MVVYYRL"/>
    <dbReference type="OrthoDB" id="121331at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01463_B">
        <property type="entry name" value="SecD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005791">
        <property type="entry name" value="SecD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027398">
        <property type="entry name" value="SecD-TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022645">
        <property type="entry name" value="SecD/SecF_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022646">
        <property type="entry name" value="SecD/SecF_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07549">
        <property type="entry name" value="Sec_GG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13721">
        <property type="entry name" value="SecD-TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02355">
        <property type="entry name" value="SecD_SecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00916">
        <property type="entry name" value="2A0604s01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01129">
        <property type="entry name" value="secD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="460"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="485"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="580"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="domain" description="SecD-TM1" evidence="10">
        <location>
            <begin position="4"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN58857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OPD61869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW27130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="619" mass="66531" checksum="0D0E80802CBC1940" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKU5</accession>
    <name>A0A0S2DKU5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3832</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3832"/>
    <dbReference type="EnsemblBacteria" id="ALN59175">
        <property type="protein sequence ID" value="ALN59175"/>
        <property type="gene ID" value="GLE_3832"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3832"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3774"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018643">
        <property type="entry name" value="DUF2069_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09842">
        <property type="entry name" value="DUF2069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="176" mass="18200" checksum="7B8062B6BD8A0C8A" modified="2016-02-17" version="1">MSASGPGAHGPGPDAARPDEAGPDNAGPGERAPAARVADGGAHERSVIDDGTAQGHAGHGATTARPGSQWVLLVCLLALAALFALWYLLPGRHWIAGLTVFVLPPALLAAGVALRSRLAGYWAGVLALFWFCHGVMLAWSSPGERLYAWIEVVLALAVIFSANLAGLKARLGRKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKZ7</accession>
    <name>A0A0S2DKZ7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8 11">50S ribosomal protein L22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">rplV</name>
        <name evidence="15" type="ORF">D9T17_09455</name>
        <name evidence="14" type="ORF">FE772_18625</name>
        <name evidence="12" type="ORF">GLE_3785</name>
        <name evidence="13" type="ORF">LEN_1358</name>
        <name evidence="16" type="ORF">SAMN05421681_1108</name>
    </gene>
    <organism evidence="12 17">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 17">C3</strain>
        </source>
    </reference>
    <reference evidence="19" key="2">
        <citation type="journal article" date="2016" name="DNA Res." volume="0" first="0" last="0">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer, Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">M497-1</strain>
        </source>
    </reference>
    <reference evidence="16 18" key="3">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">ATCC 29487</strain>
        </source>
    </reference>
    <reference evidence="13 19" key="4">
        <citation type="journal article" date="2017" name="DNA Res." volume="24" first="169" last="177">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
            <dbReference type="PubMed" id="28065880"/>
            <dbReference type="DOI" id=".1093/dnares/dsw055"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 19">M497-1</strain>
        </source>
    </reference>
    <reference evidence="15 20" key="5">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 20">OH11</strain>
        </source>
    </reference>
    <reference evidence="14 21" key="6">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 21">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="7">This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="8 11">This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8 10">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 9">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP014940">
        <property type="protein sequence ID" value="BAV96845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000023">
        <property type="protein sequence ID" value="ROU07358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNOG01000010">
        <property type="protein sequence ID" value="SDY03094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_055902442.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3785"/>
    <dbReference type="EnsemblBacteria" id="ALN59129">
        <property type="protein sequence ID" value="ALN59129"/>
        <property type="gene ID" value="GLE_3785"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAV96845">
        <property type="protein sequence ID" value="BAV96845"/>
        <property type="gene ID" value="LEN_1358"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY03094">
        <property type="protein sequence ID" value="SDY03094"/>
        <property type="gene ID" value="SAMN05421681_1108"/>
    </dbReference>
    <dbReference type="KEGG" id="lem:LEN_1358"/>
    <dbReference type="KEGG" id="lez:GLE_3785"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3729"/>
    <dbReference type="OMA" id="KRIQPRA"/>
    <dbReference type="OrthoDB" id="1666043at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000183696">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000218824">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00336">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01331_B">
        <property type="entry name" value="Ribosomal_L22_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_L22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018260">
        <property type="entry name" value="Ribosomal_L22/L17_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_L22/L17_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005727">
        <property type="entry name" value="Ribosomal_L22_bac/chlpt-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501">
        <property type="entry name" value="PTHR13501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="SSF54843"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01044">
        <property type="entry name" value="rplV_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00464">
        <property type="entry name" value="RIBOSOMAL_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 8 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8 10" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN59129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="BAV96845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW27356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROU07358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="SDY03094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000183696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000218824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="111" mass="11991" checksum="DBBF1FAE3D808D64" modified="2016-02-17" version="1">MEAKAILRTARISPQKARLVADQVRGLSAERAVNLLKFSDKKAAALIRKVVESAIANAENNQGADVDDLKVKTIMVDEGPALKRFMARAKGRGTRILKRTSHITVVVGAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL00</accession>
    <name>A0A0S2DL00_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytidine and deoxycytidylate deaminase zinc-binding domain protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Nucleoside deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_19140</name>
        <name evidence="2" type="ORF">GLE_3896</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948629.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3896"/>
    <dbReference type="EnsemblBacteria" id="ALN59239">
        <property type="protein sequence ID" value="ALN59239"/>
        <property type="gene ID" value="GLE_3896"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3896"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3834"/>
    <dbReference type="OMA" id="LVVNWRP"/>
    <dbReference type="OrthoDB" id="1890883at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="1">
        <location>
            <begin position="32"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="191" mass="20937" checksum="6C9A18D4A706F75E" modified="2016-02-17" version="1">MSTKIQNPLTRQVQLLLPDWVDAAVDRSRVYASDEDKVALAVELSRRNVELRTGGPFGAAVFDGHGRVVGVGVNRVVPQNCSVAHAEMMAFMCAQTAVSQFRLNELGPMTLATSAQPCCMCYGASFWAGINNLLIGARSEDVMRLTEFDEGPLPADWIGELERRGIAVRRDLQREAACEVLRKYGESGVSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLE0</accession>
    <name>A0A0S2DLE0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ATP-dependent helicase</fullName>
            <ecNumber evidence="6">3.6.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">dinG</name>
        <name evidence="6" type="ORF">GLE_3970</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.1.-" evidence="6"/>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="ALN59312"/>
        <property type="gene ID" value="GLE_3970"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
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        <property type="project" value="InterPro"/>
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="2"/>
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        <property type="entry name" value="ATP-dep_Helicase_C"/>
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        <property type="entry name" value="DinG/Rad3-like"/>
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        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
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        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="PTHR11472"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
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    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="19"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="383"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="713" mass="77398" checksum="F542BD52AFB49F95" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLG6</accession>
    <name>A0A0S2DLG6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Polyphosphate kinase 2</fullName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ppk2</name>
        <name evidence="7" type="ORF">FE772_18820</name>
        <name evidence="6" type="ORF">GLE_3822</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.1" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="QCW27386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948577.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3822"/>
    <dbReference type="EnsemblBacteria" id="ALN59165">
        <property type="protein sequence ID" value="ALN59165"/>
        <property type="gene ID" value="GLE_3822"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3822"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3764"/>
    <dbReference type="OMA" id="ESTQWYY"/>
    <dbReference type="OrthoDB" id="953793at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:polyphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016898">
        <property type="entry name" value="Polyphosphate_phosphotransfera"/>
    </dbReference>
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        <property type="entry name" value="PPK2-related"/>
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        <property type="entry name" value="PPK2_PA0141"/>
    </dbReference>
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        <property type="entry name" value="PPK2"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PPK2_P_aer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPK2" evidence="5">
        <location>
            <begin position="4"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="231"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009924"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW27386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="269" mass="30417" checksum="796837450993AE25" modified="2016-02-17" version="1">MSKLKRKDYEAQLEPLQLELAAMGRWLQHSGKRLMVIFEGRDTAGKGGAIGSISENLNPRQCHIAALSKPSEREAGQWYFQRYVPHLPAAGEIVLFDRSWYNRAGVEQVMGFAKPEQVKAFLKQAPMFEKLLVDDGILLFKYWLCCDQAQQEERFAERLNDPLKRWKLSPIDLQARAHYDDYTRAREAMLEATHTKHAPWTLVDFNDQRQGRLSLIRDLLSRLPDTEVAPAKLDFPPLKGKPAKEKFGVLKPIGGKSGGKSGGKSGDKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLK2</accession>
    <name>A0A0S2DLK2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59463">
        <property type="protein sequence ID" value="ALN59463"/>
        <property type="gene ID" value="GLE_4121"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4121"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4063"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="49" mass="5404" checksum="E06E3C6115FC1E6A" modified="2016-02-17" version="1">MPWAVGLIRPRPGIRDSGSARAPMPIPSRPRRSRALLPNPRPRDPRPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLP5</accession>
    <name>A0A0S2DLP5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Electron transfer flavoprotein beta subunit</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Electron transfer flavoprotein subunit beta/FixA family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">EtfB protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">etfB</name>
        <name evidence="5" type="ORF">BV903_04380</name>
        <name evidence="6" type="ORF">FE772_20730</name>
        <name evidence="4" type="ORF">GLE_4233</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">C3</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ETF beta-subunit/FixA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000008">
        <property type="protein sequence ID" value="OPD65162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948889.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000008.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4233"/>
    <dbReference type="EnsemblBacteria" id="ALN59574">
        <property type="protein sequence ID" value="ALN59574"/>
        <property type="gene ID" value="GLE_4233"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65162">
        <property type="protein sequence ID" value="OPD65162"/>
        <property type="gene ID" value="BV903_04380"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4233"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4174"/>
    <dbReference type="OMA" id="YNGGMVP"/>
    <dbReference type="OrthoDB" id="1027643at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01714">
        <property type="entry name" value="ETF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012255">
        <property type="entry name" value="ETF_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033948">
        <property type="entry name" value="ETF_beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21294">
        <property type="entry name" value="PTHR21294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000090">
        <property type="entry name" value="Beta-ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ETF" evidence="3">
        <location>
            <begin position="23"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD65162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW27702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="248" mass="26711" checksum="666A726444CB0A9B" modified="2016-02-17" version="1">MKILVGYKRVVDYNVRIQVKPDGSGVVTDGVKLSANPFDEIALEEALRLRDKGIATEVVVATIAPADAQAHLRNGLAMGANRAIHVVSDQPIQPLTAARTLLKLIEKEQPDIVILGKQAIDDDANQTGQMLATLWGRPQATFASKLEVADGKATVTREVDAGLETLEVDLPAVVTTDLRLNEPRFIKLPDIMKAKSKPLETIQFADLGVDAGDTLKTTHYAPPPKRSKGVMVKDAAELVAALKQKGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM61</accession>
    <name>A0A0S2DM61_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4478</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949085.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59819">
        <property type="protein sequence ID" value="ALN59819"/>
        <property type="gene ID" value="GLE_4478"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4478"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4415"/>
    <dbReference type="OrthoDB" id="2161064at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="232" mass="25387" checksum="99D64AE1119C52C8" modified="2016-02-17" version="1">MGPRDRQHSIRLKAPGLLALLLFAAVLAVAVPALRKPEHEGWIALPPQPMEATGPDIRELLRKSAQFAPAGEPPLAASCGADEVEAERLPPDFARPPAPAQTDDAPIRQRYAVLIGGPDRKTWRLDLRLDGERARLRALAPGAAATERELPLAALAPLREALSAPELWSAPQRSSVFCADRHRLRQAFFEACIDGRYYARDRACDRNAWPLLDGLWRQARALTTDAAPTPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM86</accession>
    <name>A0A0S2DM86_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948654.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59272">
        <property type="protein sequence ID" value="ALN59272"/>
        <property type="gene ID" value="GLE_3930"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3930"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3867"/>
    <dbReference type="OMA" id="ICIERTP"/>
    <dbReference type="OrthoDB" id="1107969at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594960" evidence="1">
        <location>
            <begin position="23"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="403" mass="43559" checksum="B5095FB078360D0D" modified="2016-02-17" version="1">MKSGWLGLLLAMSALGAPAAFAAADAAAAAPTTVIVLGVDHAAQLVSERDRPALLDAFLDRAKPDAICIERTPEAFARGDFYEFTYEAQDVAVPFARRRGIELCPIDWEPPVEDQRLGFGLALDAPPELRPLNGMFGFLSFAAPSLQRDLFHADDPAKLEKVTNWAATPAAKARHDLPRRLYLYRTYLQAQRVAAAARAHPGGRVVVVVGEFHKRDIEAILADEPGLRLVQPSSLGRPSEAEAAAHDRPEYQAAIAGFNLLGVQAASGAVDYAFVGRALAALEAGGATPQTRLLRVRLELRQGRIARAEAIARYGAIAAEAGAARFGWTGVKDAGRVDSWFDPFGNLDVRRRALLEAARETLAQGDAAAASVLLDQCAAGLSPRQQEQLRGYWRRDIEPRERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMA7</accession>
    <name>A0A0S2DMA7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-demethoxyubiquinol 3-hydroxylase</fullName>
            <shortName evidence="7">DMQ hydroxylase</shortName>
            <ecNumber evidence="7">1.14.99.60</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">coq7</name>
        <name evidence="8" type="ORF">GLE_4263</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + AH2 + O2 = A + a 3-demethylubiquinol + H2O</text>
            <dbReference type="Rhea" id="RHEA:50908"/>
            <dbReference type="Rhea" id="RHEA-COMP:10859"/>
            <dbReference type="Rhea" id="RHEA-COMP:10914"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:84167"/>
            <dbReference type="ChEBI" id="CHEBI:84422"/>
            <dbReference type="EC" id="1.14.99.60"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="7">Binds 2 iron ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the COQ7 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.60" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4263"/>
    <dbReference type="EnsemblBacteria" id="ALN59604">
        <property type="protein sequence ID" value="ALN59604"/>
        <property type="gene ID" value="GLE_4263"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4263"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4202"/>
    <dbReference type="OMA" id="NPLWYGG"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008682">
        <property type="term" value="F:3-demethoxyubiquinol 3-hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01042">
        <property type="entry name" value="DMQH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01658">
        <property type="entry name" value="COQ7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011566">
        <property type="entry name" value="Ubq_synth_Coq7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11237">
        <property type="entry name" value="PTHR11237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03232">
        <property type="entry name" value="COQ7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0830">Ubiquinone</keyword>
    <keyword evidence="1 7" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="202" mass="21963" checksum="37DBBFFCAA3CDBBB" modified="2016-02-17" version="1">MLSEAQRALDTVFGAPLAERPNPAGSTAELVLEPQEKRHSAGLMRINHVGEVCAQALYCGQAAVARDESTREHLLHAAQEETDHLAWCADRLRELDSRPSLLNPVWYAGSFAIGALAGLRGDGWNLGFVVETERQVEAHIDEHLESLPEGDQRSRAILRTMKADEARHAANAEAAGARILPMPVPTIMAAASKVMKAVAYRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMG0</accession>
    <name>A0A0S2DMG0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59931">
        <property type="protein sequence ID" value="ALN59931"/>
        <property type="gene ID" value="GLE_4590"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4590"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="105" mass="11967" checksum="1C6CBCFE9AFEEE1B" modified="2016-02-17" version="1">MRASGHDRSSVYSELLVPICWLHACSTDRTGGCRNGRTSEGRGPSRSASSRSCRRWTGLQVSRCIRLRPNRYRQRCGAFGSGRGKQRKRLDRVNERPQCMSRKIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMG1</accession>
    <name>A0A0S2DMG1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">LPS export ABC transporter permease LptG</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="10">Putative permease, YjgP/YjgQ family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">lptG</name>
        <name evidence="11" type="ORF">BV903_04210</name>
        <name evidence="12" type="ORF">FE772_20555</name>
        <name evidence="10" type="ORF">GLE_4191</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">C3</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the LptF/LptG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000008">
        <property type="protein sequence ID" value="OPD65131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948858.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000008.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4191"/>
    <dbReference type="EnsemblBacteria" id="ALN59533">
        <property type="protein sequence ID" value="ALN59533"/>
        <property type="gene ID" value="GLE_4191"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65131">
        <property type="protein sequence ID" value="OPD65131"/>
        <property type="gene ID" value="BV903_04210"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4191"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4133"/>
    <dbReference type="OMA" id="WFTSKLA"/>
    <dbReference type="OrthoDB" id="1558251at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030923">
        <property type="entry name" value="LptG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005495">
        <property type="entry name" value="LptG/LptF_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33529">
        <property type="entry name" value="PTHR33529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03739">
        <property type="entry name" value="LptF_LptG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04408">
        <property type="entry name" value="LptG_lptG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="103"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="284"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="314"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="344"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OPD65131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW27670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="366" mass="40661" checksum="738E7DEE173E9EA4" modified="2016-02-17" version="1">MKPFPKIHDIYVGRVVLSTVLLTWAVLLGLDFMLSFVGEFGDIGKGRYGIMQALAYMALTVPRRAYALFPYASVVGSLMALGQLASTSELTVLRAVGLSRRRLSIAVAGALALLTLLMVFNGETLAPAAQRRAESLKAAAKSNNQVVAEYSGLWAREGDVILAASQGQERSQGADRWLELRNVNLYQFGADGRLVSIAVAGVAEHRPGGWLLRDVTRTTFHEKSAEKKHIAEERWESKLDSSALMSGTNRPRYLSATALHKAIEDRQRNQLDAGEFEAHYWGRWFYPLNVLALCLAAVPFAFGSLRSGGMSKRLFIGIVFALMFWLLQNQFVELAKVFRFDFRLAYLMPTVVMLSVSAFLFRRRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMK0</accession>
    <name>A0A0S2DMK0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.48</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4421</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.48" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4421"/>
    <dbReference type="EnsemblBacteria" id="ALN59762">
        <property type="protein sequence ID" value="ALN59762"/>
        <property type="gene ID" value="GLE_4421"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4421"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4359"/>
    <dbReference type="OMA" id="NEVLWFM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595458" evidence="1">
        <location>
            <begin position="26"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="2">
        <location>
            <begin position="107"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="382" mass="41306" checksum="8A22145B1A8F76D4" modified="2016-02-17" version="1">MNAFALRPWSLGLALYAACLGSAFAATPAAAAPPPAAEAAFDDGPYIRYGDGELIARWVCAGKVLERRYPAARWPVRVPPRCGFERPILVRAPAQPPADAADAAAARIAALSDVHGQYDLLVRLLQAHGIVGRDLRWRYGHGHLVVVGDVFDRGPKVNQALWLLYSLEQQAREAGGGVHYLIGNHEAMALGGDLRYVNPGYQRSAAALGETYPQLYGPDSVLGQWLRTRPAIARVGGLLFVHGGISPDYLAGDGDIERGNALYRASLGTPKAVWQDDPRLSPLYNGKTSPIWYRGYFTDPALQREQVDAIAARLGVSRIVVGHTTHHHIASYFDGRVIGVDSGLKNGESGEILLVEDGRFSRGALDGGRLPLLPGERLRDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMZ8</accession>
    <name>A0A0S2DMZ8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Efflux RND transporter periplasmic adaptor subunit</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_22250</name>
        <name evidence="5" type="ORF">GLE_4559</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949145.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4559"/>
    <dbReference type="EnsemblBacteria" id="ALN59900">
        <property type="protein sequence ID" value="ALN59900"/>
        <property type="gene ID" value="GLE_4559"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4559"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4495"/>
    <dbReference type="OMA" id="NNDTRIW"/>
    <dbReference type="OrthoDB" id="1174564at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242247" evidence="3">
        <location>
            <begin position="21"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="154"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="22"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW27963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="344" mass="35495" checksum="8221DEE9D19547D8" modified="2016-02-17" version="1">MKPELLIAAGLLALSLSACGGASDQDKAAPAAAAQGKDDHADEGDSGHAHKEAEGEAGHGESAPGKGGGEETPEAATIPNEIARRSGIVAAAAGPGTVADEHDVQGLITPLEGRVARITARYPGPVRSLRANIGDAVKAGQTLATIDSNLSLTTYGISAPISGVVLARNASVGEVAVEGTPLFEIADLSTLWVDLHVFGADASHLRPGLPVTVMRMGEDKGVDTVIDRILPGTATASQSTVARASIKNPDGLWRPGSAVHARVTVEQQPVALAVPLTALQRMDDGDVVFVRDGERYSARPVKLGRRDARRAEVLSGLKAGEQVVVEQSFLIKADIEKSGASHEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN11</accession>
    <name>A0A0S2DN11_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Tyrosine recombinase XerC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11 15" type="primary">xerC</name>
        <name evidence="15" type="ORF">GLE_4532</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the 'phage' integrase family. XerC subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4532"/>
    <dbReference type="EnsemblBacteria" id="ALN59873">
        <property type="protein sequence ID" value="ALN59873"/>
        <property type="gene ID" value="GLE_4532"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4532"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4468"/>
    <dbReference type="OMA" id="HSFASHM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009037">
        <property type="term" value="F:tyrosine-based site-specific recombinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01808">
        <property type="entry name" value="Recomb_XerC_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011931">
        <property type="entry name" value="Recomb_XerC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023009">
        <property type="entry name" value="Tyrosine_recombinase_XerC/XerD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02899">
        <property type="entry name" value="Phage_int_SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02224">
        <property type="entry name" value="recomb_XerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="6 11" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="4 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0229">DNA integration</keyword>
    <keyword evidence="9 11" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="8 11 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="14">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="13">
        <location>
            <begin position="108"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <feature type="active site" description="O-(3'-phospho-DNA)-tyrosine intermediate" evidence="11">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ALN59873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="297" mass="33038" checksum="1271AB5C781059E3" modified="2016-02-17" version="1">MRGMNPVDAFLDHLRVEKRMSAHTLDAYRRDLDALTVWTLQHAGGDVLALQAEDIRAFIAAEHRRGLTPKSLQRRLSACRSFYAWQVRQGALEASPAAPIRAPKAPRKLPQVLDPDEAKSLVEVDTDAPLGLRDRALLELFYSSGLRLSELCALRWRDLDLDDALVTVLGKGNKQRSVPLGSHARAALGEWRASTGAANDAFVFPGRGGAQISARAVQLRVRALAQRQGLFKRVHPHLLRHSFASHILESSGDLRGVQELLGHADISTTQIYTHLDFQHLAKVYDAAHPRAKRKREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN14</accession>
    <name>A0A0S2DN14_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DegV family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4338</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948974.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4338"/>
    <dbReference type="EnsemblBacteria" id="ALN59679">
        <property type="protein sequence ID" value="ALN59679"/>
        <property type="gene ID" value="GLE_4338"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4338"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4277"/>
    <dbReference type="OMA" id="HHIESTF"/>
    <dbReference type="OrthoDB" id="1554133at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004371">
        <property type="term" value="F:glycerone kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003797">
        <property type="entry name" value="DegV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043168">
        <property type="entry name" value="DegV_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004007">
        <property type="entry name" value="DhaL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036117">
        <property type="entry name" value="DhaL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033470">
        <property type="entry name" value="UPF_DhaK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02734">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02645">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01121">
        <property type="entry name" value="Dak1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01120">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101473">
        <property type="entry name" value="SSF101473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00762">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51482">
        <property type="entry name" value="DEGV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51480">
        <property type="entry name" value="DHAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DhaL" evidence="2">
        <location>
            <begin position="11"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="612" mass="64095" checksum="2E9D04B62EB9E20B" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN28</accession>
    <name>A0A0S2DN28_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DMSO reductase anchor subunit (DmsC)</fullName>
            <ecNumber evidence="2">1.8.99.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dmsC</name>
        <name evidence="2" type="ORF">GLE_4548</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.8.99.-" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949139.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4548"/>
    <dbReference type="EnsemblBacteria" id="ALN59889">
        <property type="protein sequence ID" value="ALN59889"/>
        <property type="gene ID" value="GLE_4548"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4548"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4484"/>
    <dbReference type="OMA" id="NPRNAWR"/>
    <dbReference type="OrthoDB" id="909963at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019645">
        <property type="term" value="P:anaerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007059">
        <property type="entry name" value="DmsC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38095">
        <property type="entry name" value="PTHR38095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04976">
        <property type="entry name" value="DmsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="317" mass="33591" checksum="383B99B95357FF38" modified="2016-02-17" version="1">MHPAFSVIFFTTLSGAGYGLMAWLGALALLQHAGLRGAPQLPSFALGAGLLASLVLVTIGLLSSTAHLGKPLRAWRAFSQWRTSWLSREGVMALLTYAPALALLGWLLALGPQRALPPAWPALAGAALAVCALLTVACTAMIYASLPPIPAWRHPLVVPVYLAFALLSGAALLAALPASFAAGRVAAWAVLALAPLTALLKWRYWRAIDRDRLPVTRGEAIGLPARAPSVFERPHTQDNYLTREMGYVLARKHAVKLRAIALALFAALPLALAALALALPAATAPLMAVAALSVLAGALVERWLFFAQARHLVTLYY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2022-05-25" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN66</accession>
    <name>Y3070_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Probable ATPase FE772_23070</fullName>
            <ecNumber evidence="4">3.6.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_23070</name>
        <name evidence="2" type="ORF">Ga0399710_4916</name>
        <name evidence="5" type="ORF">GLE_4746</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="journal article" date="2015" name="BMC Genomics" volume="16" first="991" last="991">
            <title>Comparative genomics and metabolic profiling of the genus Lysobacter.</title>
            <authorList>
                <person name="de Bruijn I."/>
                <person name="Cheng X."/>
                <person name="de Jager V."/>
                <person name="Exposito R.G."/>
                <person name="Watrous J."/>
                <person name="Patel N."/>
                <person name="Postma J."/>
                <person name="Dorrestein P.C."/>
                <person name="Kobayashi D."/>
                <person name="Raaijmakers J.M."/>
            </authorList>
            <dbReference type="PubMed" id="26597042"/>
            <dbReference type="DOI" id="10.1186/s12864-015-2191-z"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="journal article" date="2019" name="Appl. Environ. Microbiol." volume="85" first="0" last="0">
            <title>Interspecies and Intraspecies Signals Synergistically Regulate Lysobacter enzymogenes Twitching Motility.</title>
            <authorList>
                <person name="Feng T."/>
                <person name="Han Y."/>
                <person name="Li B."/>
                <person name="Li Z."/>
                <person name="Yu Y."/>
                <person name="Sun Q."/>
                <person name="Li X."/>
                <person name="Du L."/>
                <person name="Zhang X.H."/>
                <person name="Wang Y."/>
            </authorList>
            <dbReference type="PubMed" id="31540995"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>YC36</strain>
        </source>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2022" name="Science" volume="375" first="221" last="225">
            <title>Bacterial gasdermins reveal an ancient mechanism of cell death.</title>
            <authorList>
                <person name="Johnson A.G."/>
                <person name="Wein T."/>
                <person name="Mayer M.L."/>
                <person name="Duncan-Lowey B."/>
                <person name="Yirmiya E."/>
                <person name="Oppenheimer-Shaanan Y."/>
                <person name="Amitai G."/>
                <person name="Sorek R."/>
                <person name="Kranzusch P.J."/>
            </authorList>
            <dbReference type="PubMed" id="35025633"/>
            <dbReference type="DOI" id="10.1126/science.abj8432"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>MUTAGENESIS OF LYS-223</scope>
        <source>
            <strain>YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 4">Involved in defense against bacteriophages. When this probable 4 gene operon (bGSDM-FE772_23060-FE772_23065-FE772_23070) is inserted into E.coli it provides nearly 100-fold protection against phages T5 and T6 and about 8-fold against phage T4. The operon without bGSDM no longer protects against phage (PubMed:35025633). Probably a nucleotide hydrolase, possibly of ATP.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949283.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60087">
        <property type="protein sequence ID" value="ALN60087"/>
        <property type="gene ID" value="GLE_4746"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4746"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4680"/>
    <dbReference type="OrthoDB" id="1099662at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword id="KW-0051">Antiviral defense</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000455582" description="Probable ATPase FE772_23070">
        <location>
            <begin position="1"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="217"/>
            <end position="224"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="mutagenesis site" description="4-gene operon no longer protects against phage." evidence="1">
        <original>K</original>
        <variation>A</variation>
        <location>
            <position position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000269" key="1">
        <source>
            <dbReference type="PubMed" id="35025633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="2">
        <source>
            <dbReference type="PubMed" id="35025633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <evidence type="ECO:0000305" key="4">
        <source>
            <dbReference type="PubMed" id="35025633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000312" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000312" key="6">
        <source>
            <dbReference type="EMBL" id="QCW28098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000312" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000312" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN60087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1068" mass="116113" checksum="CD12FBC564350833" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNA7</accession>
    <name>A0A0S2DNA7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Xanthine dehydrogenase accessory factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4566</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949148.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4566"/>
    <dbReference type="EnsemblBacteria" id="ALN59907">
        <property type="protein sequence ID" value="ALN59907"/>
        <property type="gene ID" value="GLE_4566"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4566"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4502"/>
    <dbReference type="OMA" id="FALGCNG"/>
    <dbReference type="OrthoDB" id="1879870at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003777">
        <property type="entry name" value="XdhC_CoxI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027051">
        <property type="entry name" value="XdhC_Rossmann_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13478">
        <property type="entry name" value="XdhC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02625">
        <property type="entry name" value="XdhC_CoxI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XdhC_CoxI" evidence="1">
        <location>
            <begin position="29"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="XdhC_C" evidence="2">
        <location>
            <begin position="193"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="341" mass="35696" checksum="CEAE716D380332DE" modified="2016-02-17" version="1">MADSPEPGSSPRSAPGGARAVLEASAAATARGDPATLALVLETEGSTYVRAGAMALFGAREGQVGWLSGGCVEPEIEQRAAEAAAAQGIDWIDIDTRSDEDLFAGSAQGCRGRLRLALLPLAGLRDWPALVDEWRRGHGDLRLDLQAGGALTAAVGDERQRWTLPAASLPWPSAPGSAEPGRWRLEIAAPPSVLVLGAGPETPTLLPLLRTLGWMTTLVERRPRWAALAALADHALARSPAQALATARAHDAALVMHHHFELDREALEHLGGDGGQGIGFVGLLGPQRRRDDLFRVLPAAARDALAARLHSPIGLALGGEGPEAIALSVAAQLQRHRHGAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNF1</accession>
    <name>A0A0S2DNF1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4757</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60098">
        <property type="protein sequence ID" value="ALN60098"/>
        <property type="gene ID" value="GLE_4757"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4757"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="137" mass="14852" checksum="56CF8A47711F20B2" modified="2016-02-17" version="1">MFAWNSHRTLSLGWVERPVVQAMSDARNFADESLSHAHAQFRAPRLHGPACAARRSAKRKLLCSQRPRPRASDSACAPGLLNLDGKRFLAAATTHLRDAANESLPMQRGASGTCVRFSGARGAAELDAAHVYTERSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNJ8</accession>
    <name>A0A0S2DNJ8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetoacetyl-CoA reductase</fullName>
            <ecNumber evidence="3">1.1.1.36</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">phbB</name>
        <name evidence="4" type="ORF">FE772_23275</name>
        <name evidence="3" type="ORF">GLE_4783</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.36" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949313.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4783"/>
    <dbReference type="EnsemblBacteria" id="ALN60124">
        <property type="protein sequence ID" value="ALN60124"/>
        <property type="gene ID" value="GLE_4783"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4783"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4717"/>
    <dbReference type="OMA" id="EFHSCDV"/>
    <dbReference type="OrthoDB" id="1601931at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018454">
        <property type="term" value="F:acetoacetyl-CoA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042619">
        <property type="term" value="P:poly-hydroxybutyrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011283">
        <property type="entry name" value="Acetoacetyl-CoA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01829">
        <property type="entry name" value="AcAcCoA_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="246" mass="25727" checksum="3712C35693FC751B" modified="2016-02-17" version="1">MTLRIAYVTSGMGSLGTAICRKLADSGHTVVAGCGPNSPRKAGWLREQRELGYDFIASEGNAADWDSTVAAFAKVKAEVGEVDVLVNNAGGTRDVLFRQMSRGDWNAVMAGNLNTLFNITKQVVDGMAARGWGRIVNIGSVSAQKGQIGQINYATAKAAMHGFTRALAQEFAARGVTVNTISPGYVASAAISAFPPDVLDRLAASVPVRRLGKPEEVASLCAWLAGDDAAFVTGADYAVNGGLQMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNP7</accession>
    <name>A0A0S2DNP7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Primosomal protein N'</fullName>
            <ecNumber evidence="9">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP-dependent helicase PriA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 11" type="primary">priA</name>
        <name evidence="11" type="ORF">GLE_4865</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the primosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the helicase family. PriA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4865"/>
    <dbReference type="EnsemblBacteria" id="ALN60206">
        <property type="protein sequence ID" value="ALN60206"/>
        <property type="gene ID" value="GLE_4865"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4865"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4797"/>
    <dbReference type="OMA" id="RCHYCGY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006268">
        <property type="term" value="P:DNA unwinding involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00983">
        <property type="entry name" value="PriA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005259">
        <property type="entry name" value="PriA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041222">
        <property type="entry name" value="PriA_3primeBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042115">
        <property type="entry name" value="PriA_3primeBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041236">
        <property type="entry name" value="PriA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040498">
        <property type="entry name" value="PriA_CRR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17764">
        <property type="entry name" value="PriA_3primeBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18074">
        <property type="entry name" value="PriA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18319">
        <property type="entry name" value="PriA_CRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00595">
        <property type="entry name" value="priA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 9" id="KW-0639">Primosome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="211"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="9">
        <location>
            <begin position="436"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="9">
        <location>
            <begin position="468"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN60206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="745" mass="80322" checksum="4C04B42D683D2E5C" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNS3</accession>
    <name>A0A0S2DNS3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 10">Phosphoenolpyruvate carboxylase</fullName>
            <shortName evidence="10">PEPC</shortName>
            <shortName evidence="10">PEPCase</shortName>
            <ecNumber evidence="5 10">4.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10 13" type="primary">ppc</name>
        <name evidence="13" type="ORF">GLE_4845</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 10">Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>oxaloacetate + phosphate = hydrogencarbonate + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:28370"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.1.1.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the PEPCase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.31" evidence="5 10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4845"/>
    <dbReference type="EnsemblBacteria" id="ALN60186">
        <property type="protein sequence ID" value="ALN60186"/>
        <property type="gene ID" value="GLE_4845"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4845"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4775"/>
    <dbReference type="OMA" id="PWVFGWT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008964">
        <property type="term" value="F:phosphoenolpyruvate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006107">
        <property type="term" value="P:oxaloacetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00595">
        <property type="entry name" value="PEPcase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021135">
        <property type="entry name" value="PEP_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022805">
        <property type="entry name" value="PEP_COase_bac/pln-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018129">
        <property type="entry name" value="PEP_COase_Lys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033129">
        <property type="entry name" value="PEPCASE_His_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30523">
        <property type="entry name" value="PTHR30523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00311">
        <property type="entry name" value="PEPcase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00150">
        <property type="entry name" value="PEPCARBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00781">
        <property type="entry name" value="PEPCASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00393">
        <property type="entry name" value="PEPCASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="8 10 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="10 11">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <feature type="active site" evidence="10 12">
        <location>
            <position position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN60186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="920" mass="100208" checksum="0A735FB0409E8BE8" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP34</accession>
    <name>A0A0S2DP34_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Integral membrane protein, TerC family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">TerC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_24555</name>
        <name evidence="7" type="ORF">GLE_5065</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TerC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949527.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5065"/>
    <dbReference type="EnsemblBacteria" id="ALN60406">
        <property type="protein sequence ID" value="ALN60406"/>
        <property type="gene ID" value="GLE_5065"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5065"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4992"/>
    <dbReference type="OMA" id="ADHAREY"/>
    <dbReference type="OrthoDB" id="1917125at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005496">
        <property type="entry name" value="Integral_membrane_TerC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022369">
        <property type="entry name" value="Integral_membrane_TerC_rswitch"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30238:SF0">
        <property type="entry name" value="PTHR30238:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03741">
        <property type="entry name" value="TerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03718">
        <property type="entry name" value="R_switched_Alx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN60406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW28346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="320" mass="35261" checksum="CC9E09BCCD652365" modified="2016-02-17" version="1">METIGSPMLWGAFAAFVVVALLVDLVLMRHGGPHKVTFKEAAWWSVGWIALALVFNAALWWYVSRESGAEVGNRIGLEFLTGYLVEKSLAVDNIFVFLMLFTYFAVPEEQRQRVLVIGILGAIVLRSVLIFAGALLLAKFHWVLYVFGAFLVFTGIKMLMAAGKSPDLEQNPVLKWMRGHLRLTDDYHDSKLSIVRDGKRWFTPLFAVIALIGVTDVIFAVDSIPAIFAITADPFIVLTSNVFAVLGLRAMFFLLQGMADRFHLLPYGLATVLVFIGAKMLLIDIYKIPILVSLLGVAAIIGTSVVLSLVRPPKPEAGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP53</accession>
    <name>A0A0S2DP53_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sulfate ABC transporter ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Sulfate ABC transporter, ATP-binding protein</fullName>
            <ecNumber evidence="7">3.6.3.25</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Sulfate/molybdate ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">cysA</name>
        <name evidence="8" type="ORF">BV903_12175</name>
        <name evidence="9" type="ORF">FE772_24195</name>
        <name evidence="7" type="ORF">GLE_4991</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.3.25" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000029">
        <property type="protein sequence ID" value="OPD63674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949468.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000029.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4991"/>
    <dbReference type="EnsemblBacteria" id="ALN60332">
        <property type="protein sequence ID" value="ALN60332"/>
        <property type="gene ID" value="GLE_4991"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63674">
        <property type="protein sequence ID" value="OPD63674"/>
        <property type="gene ID" value="BV903_12175"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4991"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4919"/>
    <dbReference type="OMA" id="HLGWEIQ"/>
    <dbReference type="OrthoDB" id="1220708at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015419">
        <property type="term" value="F:ABC-type sulfate transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102025">
        <property type="term" value="F:ABC-type thiosulfate transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041193">
        <property type="entry name" value="CysA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005666">
        <property type="entry name" value="Sulph_transpt1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17850">
        <property type="entry name" value="CysA_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00968">
        <property type="entry name" value="3a0106s01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0764">Sulfate transport</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="3"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN60332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD63674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW28284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="347" mass="38050" checksum="33E2DD3C6C65ADE4" modified="2016-02-17" version="1">MDLHLKAIAKRYANVAALDAVDLDVASGELVALLGPSGSGKTTLLRVIAGLLQPDSGQMLFGQTDATRLSLRERNVGFVFQHYALFKHMTVAENIAFGLRSRPRARRPDKAAIAARVRELLGLIQLPELGSRYPEQLSGGQKQRVALARALAIDPTVLLLDEPFGALDAKVRVELRRWLRRLHDQTGQTTLFVTHDQEEALELADRVVVLKDGRIEQIGTPDEIYSAPASAYVFDFIGRANVIDGQTEGGELSVDGHGLRLPVDLHSRSRARLYVRPHDIGLVGEGEGLPARVLSSHRLAERITLELNVEGQARPLELDLVATPDAVTPASGSLVHVRPLRYRVYSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPE4</accession>
    <name>A0A0S2DPE4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5125</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60466">
        <property type="protein sequence ID" value="ALN60466"/>
        <property type="gene ID" value="GLE_5125"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5125"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5050"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="236" mass="25672" checksum="46D00EE0EB71D4F1" modified="2016-02-17" version="1">MASSLPFPAPVTDAAPSPEALRAAADRLVSALAAHSDPEYRLSVLKRVVRRLGEDRYPLFIRLLGVVAESDDVRAQRLLADTFGTALRRMDLPGGALSSWGATRLPDATGPVAVSALSGHFFGATPRRLLGPVEYLTVWHLQRTQRTALGAETFRTALARLIALLNRSEDARTLYPQKLAADAQNEMEGAYTRATRERLRALADAWRAGRSPEEVAQAALEVADAPLPGQWVVRDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPF2</accession>
    <name>A0A0S2DPF2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-demethylubiquinone-9 3-methyltransferase domain protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">VOC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_24655</name>
        <name evidence="2" type="ORF">GLE_5085</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949545.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
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    <dbReference type="KEGG" id="lez:GLE_5085"/>
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        <property type="project" value="UniProtKB-KW"/>
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    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
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        <location>
            <begin position="3"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="150" mass="16320" checksum="C0F188637CF04551" modified="2016-02-17" version="1">MQLTTYLSFDGDCREAFETYQTILGGKIHALMPFGDNPGCEGLAAAEREKIMHGCYELDGFMLMGTDATEQYPYQGVKGAHVTLSLNDPEQAARIFKALAQGGKIEMPLQETFWALAYGILTDRFGVPWMVNCVQAMGCVDGEGHGQAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPI2</accession>
    <name>A0A0S2DPI2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4956</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4956"/>
    <dbReference type="EnsemblBacteria" id="ALN60297">
        <property type="protein sequence ID" value="ALN60297"/>
        <property type="gene ID" value="GLE_4956"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4956"/>
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    <dbReference type="OMA" id="TWTAVMQ"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
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        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0472">Membrane</keyword>
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        <location>
            <begin position="522"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="566"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="606"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="636"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="70"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="667" mass="72412" checksum="D54EE991FE3CAA45" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPV2</accession>
    <name>A0A0S2DPV2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LysR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_25305</name>
        <name evidence="4" type="ORF">GLE_5229</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5229"/>
    <dbReference type="EnsemblBacteria" id="ALN60570">
        <property type="protein sequence ID" value="ALN60570"/>
        <property type="gene ID" value="GLE_5229"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5229"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5147"/>
    <dbReference type="OMA" id="HNCLGFS"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
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        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="3">
        <location>
            <begin position="3"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="354"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="357"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW28474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="388" mass="42535" checksum="26876511A6F682C9" modified="2016-02-17" version="1">MAHDLNDTLIFVKVVESGSFIAAAQALRLPKTTVSRKVQELETRLGAQLLHRTTRKLGLTEAGNVYYEHCQRIARELAEAESAVGQLQGGPRGWLRITAPYSVGITWIAPLLGEFHARHPEVRVEMNLSNETVDMIDQGIDVALRLGSLPDSNLIARKLAVFRTQIYASPNYLARHGEPLHPDDLRHHRTLAMPKSRRSNNEYVWPLSDGERTVDYVVDPVMVANDPGPLRGALLCGEALMLAADVTVKAFAEQGYVQRVLAGWTGPEYEFNAVFPRGQVQSPKVRAFVDFLVERLNFDADYMQVLCPDAKRFRKASEEAEAAMAHGLAKEAGDTRAIAVPVVEAIEAIAEAMDNGGKRPAKARGAAKADAAPARRDDTPSDEDAALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPW7</accession>
    <name>A0A0S2DPW7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_25565</name>
        <name evidence="1" type="ORF">GLE_5287</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949691.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60628">
        <property type="protein sequence ID" value="ALN60628"/>
        <property type="gene ID" value="GLE_5287"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5287"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5205"/>
    <dbReference type="OMA" id="APRAHIR"/>
    <dbReference type="OrthoDB" id="1006710at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="222" mass="23862" checksum="A46D5516943815DD" modified="2016-02-17" version="1">MDPRISVNKLGEYMTATPARRRQIVRDQKHVPAVKAVRYQHAREAISGLIASGLADGARAHGIAQALRREAGGSEFETQDRAHSADAIDSFVELSAGFDLDSLVPVAADARCADGIELAGVRVVARPDALLLDPQSGEAVGCVKLHFSKSQPLNETGANYVAAALQAHLERKLSAPGVVRPSRCYVVDIATRRIYTAPKASKRRLDGLTAACAEIKDRWDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ00</accession>
    <name>A0A0S2DQ00_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxymuconolactone decarboxylase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_06770</name>
        <name evidence="4" type="ORF">FE772_23890</name>
        <name evidence="2" type="ORF">GLE_4923</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000012">
        <property type="protein sequence ID" value="OPD64729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949418.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000012.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4923"/>
    <dbReference type="EnsemblBacteria" id="ALN60264">
        <property type="protein sequence ID" value="ALN60264"/>
        <property type="gene ID" value="GLE_4923"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64729">
        <property type="protein sequence ID" value="OPD64729"/>
        <property type="gene ID" value="BV903_06770"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4923"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4852"/>
    <dbReference type="OMA" id="KFMEFSM"/>
    <dbReference type="OrthoDB" id="1893149at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004675">
        <property type="entry name" value="AhpD_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00778">
        <property type="entry name" value="ahpD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="12"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="159" mass="18061" checksum="9A2A50A014FA5011" modified="2016-02-17" version="1">MTQRLDYQQQSPELFKKLVDFSMATKKPSLGHTLLDLVNIRASQLNGCGFCLDMHVKEATIRGERPLRLHHVAIWRESTLFAPRERAALAWTEALTQLSPQGVPDELYDRVRTQLSEQEIVELTYAVMTINAWNRINVAFRATPGSHDKAFGLDKAQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ06</accession>
    <name>A0A0S2DQ06_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">DNA gyrase subunit B</fullName>
            <ecNumber evidence="4 12">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12 14" type="primary">gyrB</name>
        <name evidence="15" type="ORF">FE772_25780</name>
        <name evidence="14" type="ORF">GLE_5335</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">C3</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="12">Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the type II topoisomerase GyrB family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the type II topoisomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="4 12"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949730.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5335"/>
    <dbReference type="EnsemblBacteria" id="ALN60676">
        <property type="protein sequence ID" value="ALN60676"/>
        <property type="gene ID" value="GLE_5335"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5335"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5252"/>
    <dbReference type="OMA" id="LWETTMH"/>
    <dbReference type="OrthoDB" id="205481at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03366">
        <property type="entry name" value="TOPRIM_TopoIIA_GyrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.670">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01898">
        <property type="entry name" value="GyrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002288">
        <property type="entry name" value="DNA_gyrase_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011557">
        <property type="entry name" value="GyrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041423">
        <property type="entry name" value="GyrB_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001241">
        <property type="entry name" value="Topo_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013759">
        <property type="entry name" value="Topo_IIA_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013506">
        <property type="entry name" value="Topo_IIA_bsu_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018522">
        <property type="entry name" value="TopoIIA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034160">
        <property type="entry name" value="TOPRIM_GyrB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00204">
        <property type="entry name" value="DNA_gyraseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00986">
        <property type="entry name" value="DNA_gyraseB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18053">
        <property type="entry name" value="GyrB_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00433">
        <property type="entry name" value="TOP2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01059">
        <property type="entry name" value="gyrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00177">
        <property type="entry name" value="TOPOISOMERASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 12 14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 12" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="13">
        <location>
            <begin position="427"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN60676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW28551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="810" mass="89180" checksum="15505AE23F570963" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQE8</accession>
    <name>A0A0S2DQE8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5497</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5497"/>
    <dbReference type="EnsemblBacteria" id="ALN60838">
        <property type="protein sequence ID" value="ALN60838"/>
        <property type="gene ID" value="GLE_5497"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5497"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5412"/>
    <dbReference type="OMA" id="LTECTVR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="71" mass="8138" checksum="8FFD18C0768D4EC3" modified="2016-02-17" version="1">MPASTTPPLASDKLLRSSELADRWQLTECTVRKWRSNNLGPEYIKVGGSIRYRLDDVLRYEQAFGERRAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQF3</accession>
    <name>A0A0S2DQF3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo/keto reductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Oxidoreductase, aldo/keto reductase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_05225</name>
        <name evidence="4" type="ORF">FE772_00295</name>
        <name evidence="2" type="ORF">GLE_5405</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000010">
        <property type="protein sequence ID" value="OPD64897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949785.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5405"/>
    <dbReference type="EnsemblBacteria" id="ALN60746">
        <property type="protein sequence ID" value="ALN60746"/>
        <property type="gene ID" value="GLE_5405"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64897">
        <property type="protein sequence ID" value="OPD64897"/>
        <property type="gene ID" value="BV903_05225"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5405"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5320"/>
    <dbReference type="OMA" id="RRMLPKY"/>
    <dbReference type="OrthoDB" id="1054546at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="19"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="333" mass="35937" checksum="5205FB8FC382B758" modified="2016-02-17" version="1">MTTLPTRRLGRNGPTVSALGLGCMGMSFAYGAADQDESLATLERALERGMTFLDTADIYGPHANEELLGGFLQGRRDQVFLATKFGFVTDPANPGARTVSGRPEYVRSAVEGSLKRLRTDRIDLYYQHRVDPNVPIEDTVGAMAELVAQGKVRYLGLSEPSAQTLERAQAVHPITAVQSEYSLWTRDPENNGVLATCERLGVGFVPYSPLGRGFLTGAITDTGSLSRDDFRLSTPRFQGDNFARNLELAQQAKDLAASKGCTPAQLALAWVLAQGEHIVPIPGTKRRKYLDDNLGAVEVTLTADDLARLDAVFAPGAAAGERYTEAGMAMIGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQI4</accession>
    <name>A0A0S2DQI4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Efflux transporter outer membrane subunit</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BV903_05275</name>
        <name evidence="6" type="ORF">FE772_00340</name>
        <name evidence="4" type="ORF">GLE_5414</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">C3</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000010">
        <property type="protein sequence ID" value="OPD64907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949794.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5414"/>
    <dbReference type="EnsemblBacteria" id="ALN60755">
        <property type="protein sequence ID" value="ALN60755"/>
        <property type="gene ID" value="GLE_5414"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64907">
        <property type="protein sequence ID" value="OPD64907"/>
        <property type="gene ID" value="BV903_05275"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5414"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5330"/>
    <dbReference type="OMA" id="WWRNFHD"/>
    <dbReference type="OrthoDB" id="1619477at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006519689" evidence="2">
        <location>
            <begin position="22"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="377"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD64907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW24346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="463" mass="48996" checksum="892790395E200353" modified="2016-02-17" version="1">MSRLRTLARTAALAAATAALAACVTVAPPPALDAPPAAWRDAPGAGIAVQRDWWRGYNDPALSQLVETALEHNTDLRLAAARVAEARALLDAQGAQQWPTLDLAGSATRARSVGAATGRPNLSTVSQPQFQAAYEVDLWGRLGSLTDAARANLLASQTGADSVRLSVAAAVASGYLGLRASDARLDVARRTLASRENALKLAQRRYDTGYTSRLELAQAQAEYRATAQVVPQLALAIRRQEDALSVLLGRAPQPIQRGRPLAEIAAPALPAAGVPSQLLRRRPDIAQGEAQIAASDASLAAARAQLLPSLRLTGSIGSLESSLLHGDPIRVWSVGGSVLAPLFNAGRLRAGVHASAARRDQAVLGYQKTVLTAFAEVEDAMAAIAHLREQREQAVQQQQALAEALRIAHNRYNEGYASYLEELDAQRNLFNAELTALQLQGDALTAEVNLYKALGGGWEAAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQJ7</accession>
    <name>A0A0S2DQJ7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_25005</name>
        <name evidence="2" type="ORF">GLE_5163</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949599.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5163"/>
    <dbReference type="EnsemblBacteria" id="ALN60504">
        <property type="protein sequence ID" value="ALN60504"/>
        <property type="gene ID" value="GLE_5163"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5163"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5085"/>
    <dbReference type="OMA" id="VQWYAAA"/>
    <dbReference type="OrthoDB" id="1318120at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726743" evidence="1">
        <location>
            <begin position="24"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="212" mass="23487" checksum="5A3E7698C04ACDB4" modified="2016-02-17" version="1">MFIRNLLLASALAAALASGAAAAQSLPKPNEFYFDADAQTARPVIAVRETGEAAMDRLAKILERKPRAPAEAAQLAHLAMEAGRTELGRQLYGRALHEIDSGSAQWRAIHWNYAWDLYHAGAGEDALKIFVTLHNARGVSASWMPPTYAVVLWSLGRKDEALQWYAAAVRTEPDQWRNASRYAELLPNWRESDRATLVEVQKAWAANPPAWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQT4</accession>
    <name>A0A0S2DQT4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_5408</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949788.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5408"/>
    <dbReference type="EnsemblBacteria" id="ALN60749">
        <property type="protein sequence ID" value="ALN60749"/>
        <property type="gene ID" value="GLE_5408"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5408"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5323"/>
    <dbReference type="OMA" id="FAHERIF"/>
    <dbReference type="OrthoDB" id="537440at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595592" evidence="1">
        <location>
            <begin position="23"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="46"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="570" mass="62036" checksum="3F4CDAAFF253EAE3" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAM0</accession>
    <name>A0A0S2DAM0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glycine--tRNA ligase alpha subunit</fullName>
            <ecNumber evidence="9">6.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glycyl-tRNA synthetase alpha subunit</fullName>
            <shortName evidence="9">GlyRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 10" type="primary">glyQ</name>
        <name evidence="11" type="ORF">FE772_01555</name>
        <name evidence="10" type="ORF">GLE_0128</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly)</text>
            <dbReference type="Rhea" id="RHEA:16013"/>
            <dbReference type="Rhea" id="RHEA-COMP:9664"/>
            <dbReference type="Rhea" id="RHEA-COMP:9683"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.14"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 9">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945815.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0128"/>
    <dbReference type="EnsemblBacteria" id="ALN55487">
        <property type="protein sequence ID" value="ALN55487"/>
        <property type="gene ID" value="GLE_0128"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0128"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.131"/>
    <dbReference type="OMA" id="SYYQFQV"/>
    <dbReference type="OrthoDB" id="676868at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006426">
        <property type="term" value="P:glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00733">
        <property type="entry name" value="GlyRS_alpha_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00254">
        <property type="entry name" value="Gly_tRNA_synth_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006194">
        <property type="entry name" value="Gly-tRNA-synth_heterodimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002310">
        <property type="entry name" value="Gly-tRNA_ligase_asu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02091">
        <property type="entry name" value="tRNA-synt_2e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01044">
        <property type="entry name" value="TRNASYNTHGA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00388">
        <property type="entry name" value="glyQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50861">
        <property type="entry name" value="AA_TRNA_LIGASE_II_GLYAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN55487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW24554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="311" mass="35340" checksum="752E10811CF7462A" modified="2016-02-17" version="1">MSATDAPTTAITFQSMIQRLNAYWAERGCVLIQPLDLEVGAGTFHPATFLRALGPEPWNAAYVQPSRRPTDGRYGENPNRLQRYYQYQVAMKPSPDNIVELYFDSLKALGVDPRVHDLRLVEDNWESPTLGAWGLGWEVWLNGMEVTQFTYFQQAGGIECKPVLGEITYGLERLCMYLQNVDNVYDLVWTYGPDGTPVTYGDVYHQNEVEQSAYNFEHADVDELFHRFDACEKEAQKLIDLGLPLPAYDQVCKASHSFNLLDARRAISVTERQRYILRVRRIAQGVAEAYFAQREKLGFPGLKQAPKAEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAN7</accession>
    <name>A0A0S2DAN7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">M23 peptidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_0263</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0263"/>
    <dbReference type="EnsemblBacteria" id="ALN55622">
        <property type="protein sequence ID" value="ALN55622"/>
        <property type="gene ID" value="GLE_0263"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0263"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.264"/>
    <dbReference type="OMA" id="FTNRGKT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045834">
        <property type="entry name" value="Csd3_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19425">
        <property type="entry name" value="Csd3_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Csd3_N2" evidence="6">
        <location>
            <begin position="165"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="5">
        <location>
            <begin position="300"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF19425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN55622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="470" mass="50830" checksum="CA9FD310279DB4E4" modified="2016-02-17" version="1">MLARHLSDGFNGRWSGRQWVQAGLFATLGMMVAAVVPGFSQSTASVRAHEPRQSLALALPPLTLARLKGETGDSWQLVRVNRGQTLGSVFKDMDIPKSTMSQILEQPGAREALMRMKPGTELGFDIPVNGSLRTFRYDQDEGHRVELSIAGDKVTDKKVIARQSQVRTVVLSGKVGKSLFRSARKVGLTPANINTLTDDIFKYDIDFNEDVGTDDRFSVVVEQTWREGELISTGPILAATFTSDGKLHTGFRFDRGGKPEYFTGDGRPLKKSFIRMPIPYARLTSGFGTRRHPVLGSIRMHAGVDYAAGTGTPIMAAGDARVQFVGWKGGYGRAVILDHGRGYTTLYGHMSNFSKIKPGQRVPQGTVIGYVGSSGMATGPHLHYEFRVNGVHRNPLSITMPPPEPLSGMALAQFRQQTAVALGRIRQVENIIYADAGPAPAAAPAVAAAAVAKTVAVAKTKGKKKKTSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAV4</accession>
    <name>A0A0S2DAV4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cyclic nucleotide-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Diguanylate cyclase (GGDEF) domain</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">GGDEF domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BV903_12845</name>
        <name evidence="9" type="ORF">D9T17_01720</name>
        <name evidence="8" type="ORF">FE772_01970</name>
        <name evidence="5" type="ORF">GLE_0226</name>
    </gene>
    <organism evidence="5 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 10">C3</strain>
        </source>
    </reference>
    <reference evidence="7 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 11">B25</strain>
        </source>
    </reference>
    <reference evidence="6" key="3">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <title>Cyclic di-GMP signaling enzymes in Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Xu G."/>
                <person name="Qian G."/>
                <person name="Liu F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">OH11</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="4">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">OH11</strain>
        </source>
    </reference>
    <reference evidence="8 13" key="5">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 13">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MG387201">
        <property type="protein sequence ID" value="ATU81889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000032">
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        <property type="entry name" value="Nucleotide_cyclase"/>
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    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="27"/>
            <end position="127"/>
        </location>
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        <location>
            <begin position="212"/>
            <end position="344"/>
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    <evidence type="ECO:0000256" key="1">
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        <source>
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            <dbReference type="PROSITE" id="PS50042"/>
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        <source>
            <dbReference type="PROSITE" id="PS50887"/>
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        <source>
            <dbReference type="EMBL" id="ALN55585.1"/>
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        <source>
            <dbReference type="EMBL" id="ATU81889.1"/>
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        <source>
            <dbReference type="EMBL" id="OPD63508.1"/>
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        <source>
            <dbReference type="EMBL" id="QCW24626.1"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ROU09060.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
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    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
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    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="349" mass="38614" checksum="BCD9C920200D0E09" modified="2016-02-17" version="1">MNRDMAAPSAGRDTDNSAMTAAPTDVAMAVLTPGEFELFAEIGRPRRVEAGQVLFRRGELGTTMFVIARGAIVLDFGDDLVTKRLGVREFFGELGLLIGDHARSADAIAATDGLLVELRHEEFQRLVDRDPSLVSYFLRRAIMRVVLNEQSLIRRLRRRNQDLEAALDSLYATTHQLNQTEELVRTDDLTGLYNRRGLTLHLQDARAAGLAETLGLVLVDCDRFKQVNDEHGHLAGDRVLQSVANILRSVAGVEDIACRLGGDEFCLLVAARTRQDVMRFADFIVHTVHGLLMIPQSPPTICPVSVGACLVSAKRDWNDWYAQADAALYQAKRLGGNRVHWQDAELSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB37</accession>
    <name>A0A0S2DB37_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">Nuclear transport factor 2 family protein</fullName>
        </submittedName>
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        <name evidence="3" type="ORF">FE772_02655</name>
        <name evidence="2" type="ORF">GLE_0373</name>
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        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
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            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55731.1"/>
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        <property type="protein sequence ID" value="QCW24734.1"/>
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    <dbReference type="EnsemblBacteria" id="ALN55731">
        <property type="protein sequence ID" value="ALN55731"/>
        <property type="gene ID" value="GLE_0373"/>
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        <property type="component" value="Chromosome"/>
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        <property type="component" value="Chromosome"/>
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        <property type="entry name" value="NTF2-like_dom_sf"/>
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        <property type="entry name" value="SnoaL-like"/>
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        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="8"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="121" mass="13535" checksum="28DBA0E9C9E49A08" modified="2016-02-17" version="1">MDIQQIADRYVELCRAGQHEQIQDELYADDAVSIEAPGHQNGPLGNVQGLDAIREKGRKFMEDVVEIHSSWCSDPVVGGDWFTLAMGIDATYKSMGRGPMTEVAVYKVRDGKIVHEQFFYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBC7</accession>
    <name>A0A0S2DBC7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ClpV1 family type VI secretion ATPase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="11">Type VI secretion system ATPase TssH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">clpV</name>
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        <name evidence="11" type="ORF">FE772_03040</name>
        <name evidence="10" type="ORF">GLE_0454</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ClpA/ClpB family.</text>
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    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW24797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946048.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0454"/>
    <dbReference type="EnsemblBacteria" id="ALN55812">
        <property type="protein sequence ID" value="ALN55812"/>
        <property type="gene ID" value="GLE_0454"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0454"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.452"/>
    <dbReference type="OMA" id="YGGERKM"/>
    <dbReference type="OrthoDB" id="44062at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017729">
        <property type="entry name" value="ATPase_T6SS_ClpV1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03345">
        <property type="entry name" value="VI_ClpV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clp R" evidence="9">
        <location>
            <begin position="9"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="538"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="448"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN55812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW24797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="928" mass="100149" checksum="E69342EB7E296370" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBE3</accession>
    <name>A0A0S2DBE3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0486</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55844">
        <property type="protein sequence ID" value="ALN55844"/>
        <property type="gene ID" value="GLE_0486"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0486"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.482"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="167" mass="19453" checksum="B057C048775BCB6C" modified="2016-02-17" version="1">MVRGFSTARRLRAAKRSIEMHSPIPMHGPLEKPGEARAAARTAADDEAGFVRLSEHEWAQFVEVARTLIQLRPAEEDNTRRFVEAVLTVMSGRRFWAQLPSERFGKWYLHHHRNLRWLERGVWLALAQRGAFGSERSRQMIGFVERQRASLQRQRARRRARLLSKDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBI0</accession>
    <name>A0A0S2DBI0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Glycosyl transferase, group 2 family protein</fullName>
            <ecNumber evidence="9">2.4.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLE_0541</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GtrA family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0541"/>
    <dbReference type="EnsemblBacteria" id="ALN55899">
        <property type="protein sequence ID" value="ALN55899"/>
        <property type="gene ID" value="GLE_0541"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0541"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.535"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007267">
        <property type="entry name" value="GtrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04138">
        <property type="entry name" value="GtrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="GtrA" evidence="8">
        <location>
            <begin position="19"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="7">
        <location>
            <begin position="163"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN55899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="396" mass="43466" checksum="F1861D68B3459AE4" modified="2016-02-17" version="1">MNALPAPTASSRLRGELARFLLVGFTAVAIDFAVYRGLLWLALDVHPAKTAGYVAGAAFGYFANRAFTFRVGARWHPRELLGFLAVYAVALAANVAVNALALAVLDRGEIALALAFVAATGVSAAMNFIGLKLFVFGADAAPAAAPRAGAAAGDSAGARTTLSLVIPCYNEAANLPLLVARLRETFRDERVEAVLVDNGSSDDSPAVLARLLEGQSRIRSVRVEVNRGYGHGILAGLRAARGEVIGWTHADMQTDPFDALRGLQLFDADADPRRLFVKGRRHGRPLGDVAFTVGMSAFETVLLGRRMWDINAQPTLFPRAFFETWREPPQDFALDLYAYHQALHQGLRVQRFPVRFGERAHGHSHWNVNWRAKLRFIKRTVDFSLRLRRELRERPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBS0</accession>
    <name>A0A0S2DBS0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0622</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55980">
        <property type="protein sequence ID" value="ALN55980"/>
        <property type="gene ID" value="GLE_0622"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0622"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.614"/>
    <dbReference type="OMA" id="GCLVEQA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000944">
        <property type="entry name" value="Tscrpt_reg_Rrf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33221">
        <property type="entry name" value="PTHR33221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02082">
        <property type="entry name" value="Rrf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51197">
        <property type="entry name" value="HTH_RRF2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="137" mass="14494" checksum="53467B4E1DFBCEB1" modified="2016-02-17" version="1">MAESPRPVTSEVLARAMRTNPVVVRRTMAGLREAGLVRSEKGHGGGWSIARPLDAITLLDIYRGIGAPGLFALGHRSDNPHCLVEKAVNHALDGAFDAAQSLLLERFGAVTLAALSADFHAGMLAAGHTIDLEHAHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC33</accession>
    <name>A0A0S2DC33_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF2884 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_04060</name>
        <name evidence="2" type="ORF">GLE_0673</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946205.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0673"/>
    <dbReference type="EnsemblBacteria" id="ALN56031">
        <property type="protein sequence ID" value="ALN56031"/>
        <property type="gene ID" value="GLE_0673"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0673"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.662"/>
    <dbReference type="OMA" id="HYFIGPG"/>
    <dbReference type="OrthoDB" id="1570370at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021307">
        <property type="entry name" value="DUF2884"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11101">
        <property type="entry name" value="DUF2884"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726793" evidence="1">
        <location>
            <begin position="24"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="260" mass="28057" checksum="E916A2FB9D52F73D" modified="2016-02-17" version="1">MPARPLFRFAAAATMLVCGAASASVEIDSRCEIDSPYQLTLNERSLILTRQDGAPKAIVMRQGRLFVDDRWVELSAQDARRLAEFERGARATMPETQAIAREAADIALAALGEVAVKLGNHPDRTQAKVAQARKQLDAGLRDAIGPTRFSGKLLGDGIGKAVGEAVPLVIGDLVGGAVSAALSGDVKRFEQLDNLDAQIEAAVKPRAESLERRSDRLCQSVRALDELENALAYRFDGRPLDLLKVDYTPAPPRTDEAGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCA2</accession>
    <name>A0A0S2DCA2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase, zinc-binding dehydrogenase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0776</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946292.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0776"/>
    <dbReference type="EnsemblBacteria" id="ALN56134">
        <property type="protein sequence ID" value="ALN56134"/>
        <property type="gene ID" value="GLE_0776"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0776"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.765"/>
    <dbReference type="OMA" id="NHICTIR"/>
    <dbReference type="OrthoDB" id="884088at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="9"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="336" mass="35109" checksum="EF9427A615E086CB" modified="2016-02-17" version="1">MDAFQLHGTTLDSLRRVERPEPRPGPGQVRIRVAAASVNYRDYALATGRYQADLPRPFVPLSDGVGRIDALGAGVAGWAVGERVLGHYTTAWLDGPFRSANHLSKLGGPLDGWLARWIVLPADAIARVPAALDDASAATLPVSGLTAWSALRTLELAPGASVLVQGSGSVSLTALQLAAARGLDVIATSGDAAKAQRLRELGARAVIDYRNTPDLAAAVRGLTGGRGVDGIVDVVGGPQFLNLLNAAVDNAHIAVIGFLDSMNVDGNLIGPIMARQLNIHGVSVGSLRDLRAFLDEVDARGIAPVVGERFAFERGADAIASIADRRGFGKPVVLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCE6</accession>
    <name>A0A0S2DCE6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0853</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946345.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0853"/>
    <dbReference type="EnsemblBacteria" id="ALN56211">
        <property type="protein sequence ID" value="ALN56211"/>
        <property type="gene ID" value="GLE_0853"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0853"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.841"/>
    <dbReference type="OMA" id="PFGHRWN"/>
    <dbReference type="OrthoDB" id="1467120at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="2"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="152" mass="16589" checksum="5559EE42324DFADE" modified="2016-02-17" version="1">MAVHELFSYLCVGDAQAAVAFYCKVFDATEKFRLVEPGGRIGHVELDLGGTTLMLCEEFPEVDIRRPVAGAGHSHTLHLHVDDADDVVARAVAAGARLAMAPRDHFYGERSGTVIDPFGHRWNIGHSIEALEPDEMQRRYDRDPGCGDATGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCG2</accession>
    <name>A0A0S2DCG2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Ion transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="13">Transporter, cation channel family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BV903_23940</name>
        <name evidence="16" type="ORF">D9T17_22905</name>
        <name evidence="15" type="ORF">FE772_04995</name>
        <name evidence="13" type="ORF">GLE_0869</name>
    </gene>
    <organism evidence="13 17">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 17">C3</strain>
        </source>
    </reference>
    <reference evidence="14 18" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 18">B25</strain>
        </source>
    </reference>
    <reference evidence="16 19" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 19">OH11</strain>
        </source>
    </reference>
    <reference evidence="15 20" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 20">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000088">
        <property type="protein sequence ID" value="OPD61387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000057">
        <property type="protein sequence ID" value="ROU04593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946357.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000057.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0869"/>
    <dbReference type="EnsemblBacteria" id="ALN56227">
        <property type="protein sequence ID" value="ALN56227"/>
        <property type="gene ID" value="GLE_0869"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61387">
        <property type="protein sequence ID" value="OPD61387"/>
        <property type="gene ID" value="BV903_23940"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0869"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.858"/>
    <dbReference type="OMA" id="KGIYWAI"/>
    <dbReference type="OrthoDB" id="1991946at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008076">
        <property type="term" value="C:voltage-gated potassium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028325">
        <property type="entry name" value="VG_K_chnl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11537">
        <property type="entry name" value="PTHR11537"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="Ion_trans" evidence="12">
        <location>
            <begin position="35"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN56227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OPD61387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW25123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROU04593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="290" mass="32593" checksum="26E6424F343569C4" modified="2016-02-17" version="1">MRLLLDPQLNPAAESGWRRRWFDIIHRHDTPPSRNFDLLLIALILASVLVIMGDSVPRFHARWSSWLYGLEWIFTVLFTIEYGLRLAVVRRPWRYALSSWGLIDLLSILPTYLSLLIPGSQSLLVVRVLRMLRLFRILKLTQYVEEGGMLVGALWRSRRKIFVFISAVLTVVVIFGALMYVVEGPEHGFTSIPTGMYWAIVTMATVGFGDIAPGTPLGRFIASVLILIGYSVIAVPTGIYTAELASSLREASHERGHLDRRGCPQCGLEGHDPEALFCRNCGHHLPTPMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCI0</accession>
    <name>A0A0S2DCI0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Rubredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLE_0875</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the rubredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0875"/>
    <dbReference type="EnsemblBacteria" id="ALN56233">
        <property type="protein sequence ID" value="ALN56233"/>
        <property type="gene ID" value="GLE_0875"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0875"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.864"/>
    <dbReference type="OMA" id="CLECHYI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00730">
        <property type="entry name" value="rubredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024934">
        <property type="entry name" value="Rubredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024935">
        <property type="entry name" value="Rubredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018527">
        <property type="entry name" value="Rubredoxin_Fe_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00301">
        <property type="entry name" value="Rubredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00163">
        <property type="entry name" value="RUBREDOXIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00202">
        <property type="entry name" value="RUBREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50903">
        <property type="entry name" value="RUBREDOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="23"/>
            <end position="74"/>
        </location>
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        <source>
            <dbReference type="ARBA" id="ARBA00001965"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00005337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="76" mass="8582" checksum="3DA8092773021265" modified="2016-02-17" version="1">MTMRVPQNLHYPPMSETAATTAYRTWMCVVCGFIYDEALGLPEEGIAAGTRWEDVPDTWTCPDCGVTKDDFEMMQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCK0</accession>
    <name>A0A0S2DCK0_LYSEN</name>
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        <name evidence="8" type="ORF">GLE_0841</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        <subcellularLocation>
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        </subcellularLocation>
    </comment>
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    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="151"/>
        </location>
    </feature>
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        <location>
            <begin position="339"/>
            <end position="952"/>
        </location>
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        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN56199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="955" mass="103532" checksum="9147B60E9C0F8CCE" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCN4</accession>
    <name>A0A0S2DCN4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
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    </gene>
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        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <property type="gene ID" value="GLE_0920"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="95" mass="9823" checksum="C8FFA2AA002EE5B3" modified="2016-02-17" version="1">MSRYPFAALSGLCLLLALWRAASALREWSADSPGSSIGELVFIVAPLTVLAGIFFVGCRWARGTAGFGGALAALLGVAALIAFFAAVSSIQLKTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCX7</accession>
    <name>A0A0S2DCX7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bleomycin resistance protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BV903_23610</name>
        <name evidence="7" type="ORF">FE772_05675</name>
        <name evidence="5" type="ORF">GLE_1016</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
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            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bleomycin resistance protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD61459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946462.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000083.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1016"/>
    <dbReference type="EnsemblBacteria" id="ALN56374">
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        <property type="gene ID" value="GLE_1016"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61459">
        <property type="protein sequence ID" value="OPD61459"/>
        <property type="gene ID" value="BV903_23610"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1016"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1004"/>
    <dbReference type="OMA" id="HHGDGTP"/>
    <dbReference type="OrthoDB" id="1900922at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
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        <location>
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            <end position="119"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD61459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW25222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="119" mass="13434" checksum="C183B8B0D202CB00" modified="2016-02-17" version="1">MRQTVIPQLRVLSAERSLPFYVDGLGFSVDWQHQFEPGFPLFLQITREGQTLFLTEHTGDCEVGGAVYLIVPDVDECHRRFRANGVTPTEAPHDTPWGSREMSVTDPDGNRLRFATDAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCY2</accession>
    <name>A0A0S2DCY2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Citrate transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">SLC13 family permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BV903_23560</name>
        <name evidence="10" type="ORF">FE772_05625</name>
        <name evidence="8" type="ORF">GLE_1004</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="ALN56362.1"/>
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        </source>
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        <source>
            <dbReference type="EMBL" id="ALN56362.1"/>
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        <source>
            <dbReference type="EMBL" id="OPD61453.1"/>
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        <source>
            <dbReference type="EMBL" id="QCW25215.1"/>
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        <source>
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        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
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    <sequence length="615" mass="64999" checksum="01121EE486A60A81" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD51</accession>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 6">C3</strain>
        </source>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
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            <dbReference type="Pfam" id="PF07411"/>
        </source>
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            <dbReference type="EMBL" id="QCW25249.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDC2</accession>
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        <submittedName>
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        </submittedName>
    </protein>
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        <name evidence="4" type="ORF">FE772_06180</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="gene ID" value="GLE_1129"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
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        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
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        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
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        <location>
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            <end position="334"/>
        </location>
    </feature>
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        <location>
            <begin position="70"/>
            <end position="326"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="334" mass="36929" checksum="F0382B35C159D36D" modified="2016-02-17" version="1">MRSLALASLLTLLAPALHAEPAPKPVAYGAELEGFDYPYPVQRYRFQSQGKAVQMAYLDVRPERANGRTVVVLHGKNFCAATWESAIAALRGAGYRVIAPDQLGFCKSSKPAHHQYSLHELAANTHALLASLGIERADIVGHSMGGMLAARYALMYPQATARLAMVNPIGLEDWKALGVPWRSVDDNYARELKTSAASIRKYQQEVYYSGQWKPEYQRWVDMLAGLYAGPGRERVAWNQALTSEMVFTQPVVHEFARLRVPTVLFIGQRDRTAINRDLADDALKARLGLYPELGRAAAKAIAGAKLVEFDDLGHSPQVEAPQRFEAALLDALRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDD1</accession>
    <name>A0A0S2DDD1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1212</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56569">
        <property type="protein sequence ID" value="ALN56569"/>
        <property type="gene ID" value="GLE_1212"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1212"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1197"/>
    <dbReference type="OMA" id="RVRLQMM"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017741">
        <property type="entry name" value="FAD-dependent_OxRdtase_HpnW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03364">
        <property type="entry name" value="HpnW_proposed"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="8"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="385" mass="41704" checksum="D175BB4A65AA3E49" modified="2016-02-17" version="1">MKNSDSALVVGAGIVGLAIARALAVRGHRVTVLERYDRAVGASVRNFGMIWPIGVTNGAAYERALRSRAIWQEVIDGAQLWHDPCGSLHVAYAQDEFEVLAQYAEANRALRPCALLGRDQALAKSPALVADGLRGALFNRDELLVDPREALAALPGYLHERYGVEFHWRTPVTAVESGRAHSGTRRFEADRVFVCSGPEFEQLFPQLYAAAPLTRCKLQMLRLAAPDDGLRLGAALCGGLSLVHYAGFQQAADVAPLRARYQAQYGELIELGIHVMAAQNGRGEITVGDSHVYAHTHDPFDEQAINARVLDYLGGFLRLREPRALQTWHGIYPKLTDGSSEFVAEPLPGVTVVNAVGGGGLGMTLSFGLAEEIVDGRYAAVRRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDD8</accession>
    <name>A0A0S2DDD8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56503">
        <property type="protein sequence ID" value="ALN56503"/>
        <property type="gene ID" value="GLE_1145"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1145"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1130"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="86" mass="8872" checksum="FC5619A90D2E0535" modified="2016-02-17" version="1">MILFFLGSRAKGAGTKWIPACAGMTGAGASAASPHHRLPSPSRPPPCRSGASRDRANPTTAQTSSSDLHAPPRVCLTAVRPRDIAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDK7</accession>
    <name>A0A0S2DDK7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">Cysteine desulfurase</fullName>
            <ecNumber evidence="4 7">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">sufS</name>
        <name evidence="10" type="ORF">FE772_06785</name>
        <name evidence="9" type="ORF">GLE_1256</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="4 7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946634.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1256"/>
    <dbReference type="EnsemblBacteria" id="ALN56613">
        <property type="protein sequence ID" value="ALN56613"/>
        <property type="gene ID" value="GLE_1256"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1256"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1240"/>
    <dbReference type="OMA" id="HKLCGPT"/>
    <dbReference type="OrthoDB" id="446447at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006534">
        <property type="term" value="P:cysteine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06453">
        <property type="entry name" value="SufS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010970">
        <property type="entry name" value="Cys_dSase_SufS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01979">
        <property type="entry name" value="sufS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="8">
        <location>
            <begin position="33"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW25409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="413" mass="44455" checksum="F08F34E00A41E6F4" modified="2016-02-17" version="1">MTVAAPTPAAIDWTAVRADFPVLTREVHGKPLIYFDSANTGQKPNAVIETVDDFYRRHNANVSRAVHTLGTEATEAYEGARAKLARFLNVRGDELVLCSGTTFAINLVAYSWALPRLKPGDAIVLTRMEHHANIVPWQLVAQRTGATIKVAELDELGRLDLAQLYSLLTPEVKLLALTHVSNVLGTVNPVREICREARKRGIATLVDGSQAAPHRALDIAAIGCDFYALTGHKMSGPTGTGALWARREHLDAMPPFIGGGEMIKEVRFEGTVFADGPRRFEAGTPNIAGFAGLGAAVDYLGALGMDNIEAREQALLERFTAALGEVPGLRIFGTAPDKAAVVSFLVEGAHAHDLATLLDLEGVAIRSGHHCAHPLMQHFGVPATCRASLAYYNTFEEIDAFVAALNKVRTLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDR1</accession>
    <name>A0A0S2DDR1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1087</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56445">
        <property type="protein sequence ID" value="ALN56445"/>
        <property type="gene ID" value="GLE_1087"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1087"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1074"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="79" mass="8415" checksum="A3FEDD7A77322A4C" modified="2016-02-17" version="1">MVATPVSRGQASAAPTAAASADGHPDLRHRAAVRVGSRKRPRISPSRVPSGIALEQASRDSATWATNPARRIAPRRPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDU1</accession>
    <name>A0A0S2DDU1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Zinc-type alcohol dehydrogenase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_06995</name>
        <name evidence="3" type="ORF">GLE_1301</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946672.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1301"/>
    <dbReference type="EnsemblBacteria" id="ALN56658">
        <property type="protein sequence ID" value="ALN56658"/>
        <property type="gene ID" value="GLE_1301"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1301"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1284"/>
    <dbReference type="OMA" id="HICTIVE"/>
    <dbReference type="OrthoDB" id="1752728at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08252">
        <property type="entry name" value="AL_MDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014182">
        <property type="entry name" value="ADH_Zn_typ-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
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        <property type="match status" value="1"/>
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    <dbReference type="SMART" id="SM00829">
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
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    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="2">
        <location>
            <begin position="13"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU364000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="338" mass="36319" checksum="8D44331CBF006BCC" modified="2016-02-17" version="1">MKAVALTRYLPIDDPQSLTDVELPAPVASGHDLLVRVEAVSVNPVDTKVRSPKPQVEAQPRVLGYDAAGTVEAVGERVSRFKVGDKVYYSGDITRPGSNSELQLVDERIVGSAPASLDAAQAAALPLTAITAWELLFQRMPFDSENGGRGKTLLVIAGAGGVGSIAIQIAKRAGFEVIATASRPQTVEWCRKMGADRVIDHRQPLAPQLKALGIEQVDAALNLADTDRYWDELGELLAPQGHVGLIVEPAGALKIGDPYKLKCIGIHWEMMFARARFGTADMIEQGRILDRVAQLIDAGELQGTHSETLGRIDAATLREAHRRLESGTTIGKLVLAGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDY2</accession>
    <name>A0A0S2DDY2_LYSEN</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1486</name>
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    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56843">
        <property type="protein sequence ID" value="ALN56843"/>
        <property type="gene ID" value="GLE_1486"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1486"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1467"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="39" mass="4224" checksum="5C9D9F7318B515B3" modified="2016-02-17" version="1">MPDPARPDPTAEAAAAHAAVAIFSVSRHCSRRPRARRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDY5</accession>
    <name>A0A0S2DDY5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1404</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56761">
        <property type="protein sequence ID" value="ALN56761"/>
        <property type="gene ID" value="GLE_1404"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1404"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="71" mass="7516" checksum="CDD166FAD7662983" modified="2016-02-17" version="1">MGSRGGWHIGGSSCAAQPGGSRDPEFLVLSCPRRRGQRDGHRVADDRATAPRAEPSFGGGRAARGPSRQMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE27</accession>
    <name>A0A0S2DE27_LYSEN</name>
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        <recommendedName>
            <fullName evidence="8">Neutral metalloproteinase</fullName>
            <ecNumber evidence="8">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLE_1464</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Extracellular zinc metalloprotease.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase M4 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946796.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1464"/>
    <dbReference type="EnsemblBacteria" id="ALN56821">
        <property type="protein sequence ID" value="ALN56821"/>
        <property type="gene ID" value="GLE_1464"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1464"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1445"/>
    <dbReference type="OMA" id="TFDAENM"/>
    <dbReference type="OrthoDB" id="1465483at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011096">
        <property type="entry name" value="FTP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023612">
        <property type="entry name" value="Peptidase_M4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001570">
        <property type="entry name" value="Peptidase_M4_C_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013856">
        <property type="entry name" value="Peptidase_M4_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07504">
        <property type="entry name" value="FTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01447">
        <property type="entry name" value="Peptidase_M4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02868">
        <property type="entry name" value="Peptidase_M4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00730">
        <property type="entry name" value="THERMOLYSIN"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 8" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0964">Secreted</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023094623" description="Neutral metalloproteinase" evidence="8">
        <location>
            <begin position="21"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="domain" description="FTP" evidence="11">
        <location>
            <begin position="116"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M4" evidence="9">
        <location>
            <begin position="259"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M4_C" evidence="10">
        <location>
            <begin position="415"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="397"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR623612-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN56821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="596" mass="61967" checksum="2A23224467EC75C8" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE48</accession>
    <name>A0A0S2DE48_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1545</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56902">
        <property type="protein sequence ID" value="ALN56902"/>
        <property type="gene ID" value="GLE_1545"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1545"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1527"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="46" mass="5179" checksum="C5674E4719B11866" modified="2016-02-17" version="1">MHAHRRVRALERHFLRINPLASPASQGCIGAARYERTHARLGSAQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE56</accession>
    <name>A0A0S2DE56_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CysB family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">HTH-type transcriptional regulator CysB</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">LysR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_09785</name>
        <name evidence="5" type="ORF">D9T17_20995</name>
        <name evidence="3" type="ORF">GLE_1232</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000021">
        <property type="protein sequence ID" value="OPD64162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000052">
        <property type="protein sequence ID" value="ROU04981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946616.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000052.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1232"/>
    <dbReference type="EnsemblBacteria" id="ALN56589">
        <property type="protein sequence ID" value="ALN56589"/>
        <property type="gene ID" value="GLE_1232"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64162">
        <property type="protein sequence ID" value="OPD64162"/>
        <property type="gene ID" value="BV903_09785"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1232"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1216"/>
    <dbReference type="OMA" id="FLRTYMY"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD64162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU04981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <sequence length="327" mass="35506" checksum="5172B43238685E0A" modified="2016-02-17" version="1">MTLTQLRYLVAIADSGLNITLAAERVHATQPGLSKQLKQLEDELGFLLFVRKGRSLEAIAPAGERVLAHARRILEEAANIRAYAANERGQHAGRLVLSTTHTQARYVLPPAIAQVKRDFPQVSVHLQAAADGEVLAHLSHGNADLAVISTAGAPPEGGLAVPLFRWRRVVLVPRAHPLAKLDRAPTLAELAAQPLISYESSTRPESSLRRAFAAGGHEPQLAMTARDADLIKTYVRTGLGVGLLAEMAVTSRDDDLKALTAPDAVPECITWAVIPRARVLRDYALELVHGLAPQIDRRDLRRVLEGNLEPAWPKAPSWIELTQSISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE68</accession>
    <name>A0A0S2DE68_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AraC family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BV903_12600</name>
        <name evidence="6" type="ORF">FE772_08165</name>
        <name evidence="4" type="ORF">GLE_1566</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">C3</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000031">
        <property type="protein sequence ID" value="OPD63554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946881.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1566"/>
    <dbReference type="EnsemblBacteria" id="ALN56923">
        <property type="protein sequence ID" value="ALN56923"/>
        <property type="gene ID" value="GLE_1566"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63554">
        <property type="protein sequence ID" value="OPD63554"/>
        <property type="gene ID" value="BV903_12600"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1566"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1546"/>
    <dbReference type="OMA" id="FVADTHS"/>
    <dbReference type="OrthoDB" id="1757088at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="3">
        <location>
            <begin position="156"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD63554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW25646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="260" mass="29409" checksum="ED86477D16CEA9B3" modified="2016-02-17" version="1">MRRSRQFHYPYRSLPGPLLLRYEALAVDTESALHRHPWGQLAFVESGSMAFAVEGEPLFAPPGYAAWIPAGMDHTSHNRREAKCRLINIAERYTPALPAAPGIVRLHPLFLAGVEDLFDRGIEIPDTPADRRLARVLIDKLLATPMLQRFVPHSDDRLLGPILDALQHAPGDNTTLEEWAQRVHTTERTLSRRCRDELGMSFSQWRQRLRFQQSIPLLELGRSVQQVSAQMGYASASAFIAMFQQFSGTTPQKFRQGKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEK3</accession>
    <name>A0A0S2DEK3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1644</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1644"/>
    <dbReference type="EnsemblBacteria" id="ALN57001">
        <property type="protein sequence ID" value="ALN57001"/>
        <property type="gene ID" value="GLE_1644"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1644"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1623"/>
    <dbReference type="OMA" id="MFRHQGK"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010699">
        <property type="entry name" value="DUF1275"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06912">
        <property type="entry name" value="DUF1275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="208" mass="21474" checksum="343C70A8CBBA536C" modified="2016-02-17" version="1">MLACVAGMVNVAGVLGFEHQALTHLTGTATLLGAAAAAGRPLAALQLFGVIAAYLAGAMLSGAIVQGRSLRLGRRYGVVLSIESALLFAAVPLFRHAPMLGGLTGAMAMGLQNAMATTFSGSVLRTTHLTGMFTDLGIGLGHALRGQDVPRRRILLSALVICGFLAGAALGAALYRQWGYRMLYLPAALTGAAGSGYALYRQLRPFSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEL8</accession>
    <name>A0A0S2DEL8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Na+/H+ antiporter NhaC family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Na+/H+ antiporter family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FE772_08580</name>
        <name evidence="8" type="ORF">GLE_1656</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946951.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57013">
        <property type="protein sequence ID" value="ALN57013"/>
        <property type="gene ID" value="GLE_1656"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1656"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1635"/>
    <dbReference type="OMA" id="AMCMIYL"/>
    <dbReference type="OrthoDB" id="580055at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018461">
        <property type="entry name" value="Na/H_Antiport_NhaC-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03553">
        <property type="entry name" value="Na_H_antiporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="300"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_antiporter" evidence="7">
        <location>
            <begin position="84"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_antiporter" evidence="7">
        <location>
            <begin position="242"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN57013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW25716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="449" mass="46268" checksum="3FF0B62076F15159" modified="2016-02-17" version="1">MNEPLRPGAPIVPSALALTPLLLFLALFFGAGLYFTAHGDAMGFYQLHAPVAILPALALAAFIAWRRGIKPLETLLEGMGDHNVVLMCLIFLLAGGFVEVSKAIGAVDAIVALGVGNVHPALLLPALFVVAGFISMSLGTSMGTIAAVAPIALGVSDASGLDRALVLGAVIGGATFGDNLSVISDTAIVASRTQGCTMREKFRENLKLALPAALGTLVLLGFLGETAPVQTPDPVSPWLILPYLIVLGLAIAGVDVIIVLSLGLVVAGLFGVFFAEDFGFAAYTTHIWDGFESMVEITLLSLLVGGLGALMKAAGGLAWLAQVIGKFARGHRSRRAGEVSIAALSATTDVFTANNTVAILISGGLARDVAQQHGVPPARAASVLDIFACVTQGILPYGAQILLAASLSKVSPLQLVGNVHYSWLLGAVTIVAMLWPSRKLKAEEAVAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF24</accession>
    <name>A0A0S2DF24_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diguanylate cyclase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Sensor domain-containing diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_09015</name>
        <name evidence="2" type="ORF">GLE_1751</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057950041.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1751"/>
    <dbReference type="EnsemblBacteria" id="ALN57106">
        <property type="protein sequence ID" value="ALN57106"/>
        <property type="gene ID" value="GLE_1751"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1751"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1727"/>
    <dbReference type="OMA" id="DPLTQLW"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="1">
        <location>
            <begin position="236"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="363" mass="39539" checksum="CAA380D1C467FD3D" modified="2016-02-17" version="1">MQKPPTPVNEAQRLQALRSYDILDTPPERDFDDLVAIAAAVCDAPIALVSLIDEQRQWFKARTGLAATQTPRELAFCAHAILRPDQTLVVPDARDDARFAGNPLVLDDPNIRFYAGAPLVTPEGHGLGTLCVIDTKPRDLADKQHQALTALSRQASRAMELRRVSRALARQLQESEWYEHRLLQYQSELEASNAALEASNADLAALTRTDPLTGLPNRRAFALALEQAVARSHAAAPLQVAVLDIDHFKTINDVHGHAEGDRVLLAVADALRLYAPGPGSVARYGGEEFMLLFEAPQPQAQLQCEFVREAIANLPLGLPLTVSIGLAAYRTGEEPAATFARADQALYAAKRGGRNRVVLAESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFC9</accession>
    <name>A0A0S2DFC9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">3-deoxy-D-manno-octulosonic acid kinase</fullName>
            <shortName evidence="7">Kdo kinase</shortName>
            <ecNumber evidence="5 7">2.7.1.166</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">kdkA</name>
        <name evidence="9" type="ORF">BV903_07145</name>
        <name evidence="8" type="ORF">GLE_1666</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">B25</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>alpha-Kdo-(2-&gt;6)-lipid IVA + ATP = 4-O-phospho-alpha-Kdo-(2-&gt;6)-lipid IVA + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28506"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:60364"/>
            <dbReference type="ChEBI" id="CHEBI:61589"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.166"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Bacterial outer membrane biogenesis; LPS core biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
            <orientation evidence="7">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the protein kinase superfamily. KdkA/RfaP family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.166" evidence="5 7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000013">
        <property type="protein sequence ID" value="OPD64658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946959.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1666"/>
    <dbReference type="EnsemblBacteria" id="ALN57023">
        <property type="protein sequence ID" value="ALN57023"/>
        <property type="gene ID" value="GLE_1666"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64658">
        <property type="protein sequence ID" value="OPD64658"/>
        <property type="gene ID" value="BV903_07145"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1666"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1645"/>
    <dbReference type="OMA" id="YYRGGLW"/>
    <dbReference type="OrthoDB" id="1643499at2"/>
    <dbReference type="UniPathway" id="UPA00958"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009244">
        <property type="term" value="P:lipopolysaccharide core region biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00521">
        <property type="entry name" value="KDO_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022826">
        <property type="entry name" value="KDO_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="7">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN57023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD64658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="249" mass="27986" checksum="42C7DC1555AAA7C0" modified="2016-02-17" version="1">MTGYDAAEGLTPYRDDSGYGAILFDRARVQQAAPEWFVPGYWGAQARPVDSGGRGGAWFVDAPFGRAVLRRYLRGGLVARFNRDRYGWRGGDRTRSFAEFRLTREAARRGLPVPAPIAALYRREGLQYRAAILVARLDDVRSLADRAAVAGDGAPWEETGRLVARCHRAGLDHADLNATNLLFDAAGRGWVIDLDRGQFRIPATGWRERNLARLKRSLLKLRGPRPPAEVERDFARLRAAYDRAWERGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFD0</accession>
    <name>A0A0S2DFD0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphatidylglycerophosphatase B-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_1747</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="ALN57102"/>
        <property type="gene ID" value="GLE_1747"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1747"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1723"/>
    <dbReference type="OMA" id="WPTRWRW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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            <begin position="60"/>
            <end position="78"/>
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            <end position="137"/>
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    <feature type="transmembrane region" description="Helical" evidence="2">
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            <end position="165"/>
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        <location>
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            <end position="256"/>
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            <begin position="144"/>
            <end position="253"/>
        </location>
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            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="270" mass="29933" checksum="CF101ED07B3FDAEB" modified="2016-02-17" version="1">MSEDPRADAAPPRSVAASVESPHPQGARSQEQHAARRRGADDSAFEQEARFGAALLRRHGWTLLLVFAGLLLPLWAFAELADDIHRQESLVYDVPVLEYAHGLSRHSLDLFFSVIAKLGYQWGVVPFDIVLVIALTVTRRFREASYAAIALGGSGLLNIAAKQFFARERPSLWESIAPEHNYSFPSGHAMGSMTLAAVLILLCWPTRWRWLVVAAMVPFTVLVGFSRLYLGVHYPSDILAGWAVATAWAVAVYLLVYRGGVRRPWQAREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFI9</accession>
    <name>A0A0S2DFI9_LYSEN</name>
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        <submittedName>
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        </submittedName>
    </protein>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
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    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
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    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2053"/>
    <dbReference type="EnsemblBacteria" id="ALN57403">
        <property type="protein sequence ID" value="ALN57403"/>
        <property type="gene ID" value="GLE_2053"/>
    </dbReference>
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    <dbReference type="PATRIC" id="fig|69.6.peg.2018"/>
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    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="term" value="P:cell wall macromolecule catabolic process"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:chitin catabolic process"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        </location>
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        </location>
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        <location>
            <begin position="118"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        <source>
            <dbReference type="Pfam" id="PF00182"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN57403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="317" mass="34063" checksum="C627EEEAAF304B1B" modified="2016-02-17" version="1">MSKLATSPLRLRTALARAAGLFGLLCAHSAFAAPQAPFADDALAPAAVAPAACNYVEWTRGVNYTLGTIVRFPPNGQFYKLVNVGTNGSDGTDPTISTWYWQPTTCDGGGPSPGGFVVSEAQFNQMFPNRNGFYTYSGLIAALRSYPNFAKEGGDTIARQEAAAFLANVHHETGGLVHIREQNQANWDHYCQPAGTCGGKQYYGRGPIQLSWNYNYSAAGNALGLDLINNPDWVATNSAISWQTALWYWMTQRGAASNTPHQAMVNLRAFGETIRAINGGIECNAGGIGHQQMLNRVQIYRGFSATLGVPAGNNLEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFJ4</accession>
    <name>A0A0S2DFJ4_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="4" type="ORF">BV903_10615</name>
        <name evidence="3" type="ORF">GLE_2064</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD63940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57414">
        <property type="protein sequence ID" value="ALN57414"/>
        <property type="gene ID" value="GLE_2064"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63940">
        <property type="protein sequence ID" value="OPD63940"/>
        <property type="gene ID" value="BV903_10615"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="28"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD63940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="278" mass="29160" checksum="0BE0D833B60283AA" modified="2016-02-17" version="1">MSASGSAPLLAAIAATALLAACQRQAAPTPTAEAPKPATAAAPTAKPAAAPAATDPAALQAAVEATMKQQYGDSFDAAQGCWKFSARFEQGGSEDYCMRAGRPEVVDLQGERRLYLAAHNVPDAEGYLYGHASSGLMGAFVLGPDGRGGWTLLAGDRQLTSGSSGYCGCDDAQLVRIGARTMAWKFASGGVWQGIVVSSYSLVAPVGDKVRDLSQIPEVAEDDQDHEYAIEIDGSDLAKPFFPLRVTQRPQQPGKGKETVQVVEFDPIKQVYALPEAK</sequence>
</entry>
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    <accession>A0A0S2DFR8</accession>
    <name>A0A0S2DFR8_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">GLE_2095</name>
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    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="69"/>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    <dbReference type="PATRIC" id="fig|69.6.peg.2059"/>
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    </dbReference>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="chain" id="PRO_5006594767" evidence="1">
        <location>
            <begin position="25"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="225" mass="23528" checksum="B45B61D6C0D11BBC" modified="2016-02-17" version="1">MPRLPVPSSAVALCMLAAAFACVAADAPTAVQQTADAAVVDLARGCWIRHAPARPDGRDTVLLRLLPDPERRDWLRGEIARVGDDPDRRLQLWLARDGRRALLSAASVRDPDAPAARVGAAPGPVPMRTPPGAIHPVLDLDPDGLARLLLGGDDRVAFGRSPRRLTAVGGTAGRSAEIDYRAEAGPPLRLRVNAAEERLSVTVGGADIGTGAPLAVFAGVRDGCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFU7</accession>
    <name>A0A0S2DFU7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Glycosyltransferase family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_10500</name>
        <name evidence="3" type="ORF">GLE_2075</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW26036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947259.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2075"/>
    <dbReference type="EnsemblBacteria" id="ALN57425">
        <property type="protein sequence ID" value="ALN57425"/>
        <property type="gene ID" value="GLE_2075"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2075"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2040"/>
    <dbReference type="OMA" id="SMTAFRF"/>
    <dbReference type="OrthoDB" id="948440at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="14"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="200"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="405" mass="44944" checksum="3C7BAFB81730D303" modified="2016-02-17" version="1">MNILMLSDVYFPRVNGVSTSIRTFAQSLARMGHAVTLVAPDYGPGSGQELHDSDEFEIVRLPARVIFFDPEDRLIRAPELRRVLPELAQRHWDVIHIHTPFQAHRLGVRLAERTGRPTVETYHTYFEEYIGHYLPWAPVALLRLVARRLSRMLCHGVDHLIVPTAQMVEVLDRYGIATPSTVLPTGIDLDEFSRGDGARFRAEHGIEATRPTLVTVSRLAVEKNIAFLLQVARRLVADFPELMFIIAGEGPDAERLKRLSKEYGLDANVRFFGNLDRRTTLLDAYRAGDAFVFASPTETQGLVLIEAMALGVPIVSTAVMGTATVLRDARSAVISEENVEDFAAHVSRVLRSPELRAQLSAAGPVDARGWSTQGLMEQVVALYQRLAQAAPRKLAASKPQAQAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGC3</accession>
    <name>A0A0S2DGC3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">D-glycerate dehydrogenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">D-isomer specific 2-hydroxyacid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_10810</name>
        <name evidence="7" type="ORF">GLE_2141</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947311.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2141"/>
    <dbReference type="EnsemblBacteria" id="ALN57491">
        <property type="protein sequence ID" value="ALN57491"/>
        <property type="gene ID" value="GLE_2141"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2141"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2105"/>
    <dbReference type="OMA" id="KMKPNCI"/>
    <dbReference type="OrthoDB" id="1638924at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh" evidence="5">
        <location>
            <begin position="12"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="2-Hacid_dh_C" evidence="6">
        <location>
            <begin position="111"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW26087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="337" mass="36262" checksum="746991F6E2849718" modified="2016-02-17" version="1">MSERPRVWVSQPLFADVLARLGEHFEVEATREVTRHEPAAVNAILRRMDGALVTLNDPIGAEQIAGAQRLRAIANVGVGYNNLDIAALSAAGILASNTPDVLTETTADFGFALMMAAARRMSEAERWLRDGHWQRWSFDSLLGADVHGATLAILGMGRIGQAIARRATGFGMRTLYHNRSRLPAAVEAECKAQYVGFDELLARADHLVLVLPYSPQSHHLIDAAALAKLQPHATLTNIARGGIVDEDALCDALEHDRLGAAGLDVYEGEPRLNPRLLQQRRVVLTPHIASGSLATRRAMVALAVDNLIAALGFGPRAGDPPSPINGGTRDRGPGTRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGG1</accession>
    <name>A0A0S2DGG1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2316</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57665">
        <property type="protein sequence ID" value="ALN57665"/>
        <property type="gene ID" value="GLE_2316"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2316"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2281"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="44" mass="4937" checksum="50C4A92455CB1962" modified="2016-02-17" version="1">MPCSGIFYTPAYGPMNRLQAPALRELASIPFCAQRIPYSPRSYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGH0</accession>
    <name>A0A0S2DGH0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">4'-phosphopantetheinyl transferase</fullName>
            <ecNumber evidence="3">2.7.8.-</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="4">4'-phosphopantetheinyl transferase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sfp</name>
        <name evidence="4" type="ORF">FE772_10610</name>
        <name evidence="3" type="ORF">GLE_2098</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.8.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947277.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2098"/>
    <dbReference type="EnsemblBacteria" id="ALN57448">
        <property type="protein sequence ID" value="ALN57448"/>
        <property type="gene ID" value="GLE_2098"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2098"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2062"/>
    <dbReference type="OMA" id="RYWTCKE"/>
    <dbReference type="OrthoDB" id="1542506at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="SSF56214"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACPS" evidence="2">
        <location>
            <begin position="114"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="277" mass="30744" checksum="AEDF4B8C48B23941" modified="2016-02-17" version="1">MHLHADDIAIWIARLDEADDSALAARWRALLDGSERARELRYRLADDRRRHLLARALARTALARHTGIAPQRLRFVRGRHGKPELAGDNPGDHRFNLSHAAGVVALAVARGRALGIDTESLRARALSLGAVERNFAADEIAELRALPAAARARRTIEHWTLKEAYAKARGIGLSLPLDRFGVRVDDARLRLWMAPGFDDAPERWRLWQFLDGEDQLLALCAQHRPDAAPARIRAIACSPLRYETPIALRLLRASGEDALPLSEASGENDGCPRLAPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGK9</accession>
    <name>A0A0S2DGK9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase, short chain dehydrogenase/reductase family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">SDR family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_12160</name>
        <name evidence="2" type="ORF">GLE_2433</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947535.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2433"/>
    <dbReference type="EnsemblBacteria" id="ALN57782">
        <property type="protein sequence ID" value="ALN57782"/>
        <property type="gene ID" value="GLE_2433"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2433"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2395"/>
    <dbReference type="OMA" id="ANAIMYA"/>
    <dbReference type="OrthoDB" id="1261526at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="246" mass="26078" checksum="F57EBC54EC005C78" modified="2016-02-17" version="1">MSLVTASPKTILVTGASSGIGEATARELARRGHRVVVGARRGERLDALCRELAGAGAQVAWRELDVTRLDDMQGFVAFAEERFGPVDVLVNNAGVMPLSPLSALKIDEWDRMLDVNVRGVLHGIAATLPGMQARGRGQIVNVSSIGGHAVWPNAAVYCATKYAVRAISDGLRQETDTIRVTIVSPGVVESELADTITDAGAREAMKAFREVALPAQAIAEAVAYAVEQPAHVDVSELIVRPTASPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGL6</accession>
    <name>A0A0S2DGL6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57729">
        <property type="protein sequence ID" value="ALN57729"/>
        <property type="gene ID" value="GLE_2380"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2380"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2341"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="300" mass="32158" checksum="E9B071E9B20C7E6B" modified="2016-02-17" version="1">MDGEGRHHRRGSHVGGGGNGGGGQRGRAKARAPRRRCRRGCARYRCADGIGFALSRRARGGCRNARSGVTGCARGMPQGSQPAGDAVPYRCAARCGGRGGRRAGKGEGRAGRREAVGFFKGLAPCREEMIRVAGGVVPGVSRAGAPWAIGGRRRTRSLLFWSGRAMPLRRNTGIETAKTVLRRSVGAVNAGARCAVQVAMVIALRGADDHTIALAPRCARRSRSRRRRARSRKTPRKWRYTKHLRAKGKAFASTRCANERSMIEWTDPANRSRRAEAGLGRRQRTADSNGGAALLAVSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGM6</accession>
    <name>A0A0S2DGM6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome bo(3) ubiquinol oxidase subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Cytochrome o ubiquinol oxidase subunit 4</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Oxidase bo(3) subunit 4</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Ubiquinol oxidase polypeptide IV</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Ubiquinol oxidase subunit 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">cyoD</name>
        <name evidence="18" type="ORF">BV903_02165</name>
        <name evidence="19" type="ORF">FE772_11885</name>
        <name evidence="17" type="ORF">GLE_2374</name>
    </gene>
    <organism evidence="17 20">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="17 20" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 20">C3</strain>
        </source>
    </reference>
    <reference evidence="18 21" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 21">B25</strain>
        </source>
    </reference>
    <reference evidence="19 22" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 22">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterooctamer of two A chains, two B chains, two C chains and two D chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome c oxidase bacterial subunit 4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000004">
        <property type="protein sequence ID" value="OPD65591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947491.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2374"/>
    <dbReference type="EnsemblBacteria" id="ALN57723">
        <property type="protein sequence ID" value="ALN57723"/>
        <property type="gene ID" value="GLE_2374"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65591">
        <property type="protein sequence ID" value="OPD65591"/>
        <property type="gene ID" value="BV903_02165"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2374"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2335"/>
    <dbReference type="OMA" id="IVVHMVF"/>
    <dbReference type="OrthoDB" id="2088013at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009486">
        <property type="term" value="F:cytochrome bo3 ubiquinol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015990">
        <property type="term" value="P:electron transport coupled proton transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005171">
        <property type="entry name" value="Cyt_c_oxidase_su4_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014210">
        <property type="entry name" value="Cyt_o_ubiqinol_oxidase_su4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03626">
        <property type="entry name" value="COX4_pro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02847">
        <property type="entry name" value="CyoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="8"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ALN57723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OPD65591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="QCW26266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="134" mass="15020" checksum="C462694FF253E01D" modified="2016-02-17" version="1">MTQSAQHHDNAHGHDDHGHDHEEHDDYHGTVKGYTIGFLLSVFLTAIPFWLVMAKVLPSSGVTAAVILAFAVVQIVVHMVYFLHMNTKSEGGWNMLALIFTIVIVVITLAGSLWVMHHLNVNMMPMPHEMRNMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGR4</accession>
    <name>A0A0S2DGR4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase, zinc-binding dehydrogenase family/NAD-binding Rossmann fold</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Zinc-binding dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_11330</name>
        <name evidence="2" type="ORF">GLE_2248</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947398.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2248"/>
    <dbReference type="EnsemblBacteria" id="ALN57597">
        <property type="protein sequence ID" value="ALN57597"/>
        <property type="gene ID" value="GLE_2248"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2248"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2213"/>
    <dbReference type="OMA" id="YVRWTER"/>
    <dbReference type="OrthoDB" id="1465613at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
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        <location>
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            <end position="365"/>
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            <dbReference type="EMBL" id="ALN57597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26175.1"/>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
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    </evidence>
    <sequence length="718" mass="76694" checksum="31372F6BAC481E5A" modified="2016-02-17" version="1"> </sequence>
</entry>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242172" evidence="1">
        <location>
            <begin position="20"/>
            <end position="853"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="853" mass="96207" checksum="46A986F3EFA4CD3E" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH40</accession>
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        <submittedName>
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        <submittedName>
            <fullName evidence="10">ABC transporter, ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FE772_12645</name>
        <name evidence="10" type="ORF">GLE_2517</name>
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    <organism evidence="10 12">
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        <lineage>
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    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ALN57866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="QCW26386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947601.1">
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN57866">
        <property type="protein sequence ID" value="ALN57866"/>
        <property type="gene ID" value="GLE_2517"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2517"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2480"/>
    <dbReference type="OMA" id="PQEPEIF"/>
    <dbReference type="OrthoDB" id="643917at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
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        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
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        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 10" id="KW-0067">ATP-binding</keyword>
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    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="282"/>
        </location>
    </feature>
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        <location>
            <begin position="36"/>
            <end position="322"/>
        </location>
    </feature>
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        <location>
            <begin position="354"/>
            <end position="607"/>
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    </feature>
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        <location>
            <begin position="390"/>
            <end position="397"/>
        </location>
        <ligand>
            <name>ATP</name>
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        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN57866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW26386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="623" mass="66862" checksum="4F3C1CA9883E971C" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHM5</accession>
    <name>A0A0S2DHM5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Kynureninase</fullName>
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        </recommendedName>
        <alternativeName>
            <fullName evidence="4">L-kynurenine hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">kynU</name>
        <name evidence="8" type="ORF">FE772_13415</name>
        <name evidence="7" type="ORF">GLE_2678</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>3-hydroxy-L-kynurenine + H2O = 3-hydroxyanthranilate + H(+) + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:25143"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36559"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:58125"/>
            <dbReference type="EC" id="3.7.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>H2O + L-kynurenine = anthranilate + H(+) + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:16813"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:57959"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="3.7.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 5">Amino-acid degradation; L-kynurenine degradation; L-alanine and anthranilate from L-kynurenine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 5">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the kynureninase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.7.1.3" evidence="4 5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947728.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2678"/>
    <dbReference type="EnsemblBacteria" id="ALN58026">
        <property type="protein sequence ID" value="ALN58026"/>
        <property type="gene ID" value="GLE_2678"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2678"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2637"/>
    <dbReference type="OMA" id="TFPTDGY"/>
    <dbReference type="OrthoDB" id="1474443at2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00329"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00334">
        <property type="reaction ID" value="UER00455"/>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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</entry>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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    </evidence>
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</entry>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
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        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="256" mass="28011" checksum="CC9205E2F1761BF7" modified="2016-02-17" version="1">MNQTITQRLSILPLALAVVVAGAAALAPVPAQAFYASEITQVLNKVQLQAQNMKLVQQLTELRNQVTQLKAQFDQLNPGNFQLGSLTGFRDKESQELSERLPAASYGLDESCQKGKSSVADDQYKVCAKRVEISNLRFNAMVKMLKEVKKRDEQIEKLMNDRKTLTGPENKGKLDANTNQVMQLQAQMENDIQNGKTTLDTYTTILQTLDDDMVALAQRALTNKPGGKGWLSSMAGAAVQGVALKAGLKAAESRDL</sequence>
</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
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    <sequence length="41" mass="4230" checksum="CFA659133F651286" modified="2016-02-17" version="1">MSCDRRGIPDVATAESGCAAFAPGNRRSPPGHRKFARAASG</sequence>
</entry>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <dbReference type="EMBL" id="ALN58387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
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        </source>
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    <sequence length="175" mass="18331" checksum="84B95DCAC9A5AC9C" modified="2016-02-17" version="1">MDAAAAAMRVAARAGGRLAGSLRSSLARAFVSAPNAGPVPGCVDWRPSRLLAAALAALGLLAGVAALASELPAHLGWPVAALAAGWGAALARRELRRPPRRLRLAGARAWLDDAPIAQAGLYWRGPLARLEFRDAQGRRGRLLWWPDSLDAHGRRELRLAAAVAIDAPAPRSVAP</sequence>
</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <source>
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    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN58317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="215" mass="23031" checksum="E85084271F37F062" modified="2016-02-17" version="1">MIPSRSTFSGWPLLGVIAIAVLAMTGLTIAAQAALVDGVHSAVRATARSSFALFLLAFTASAFAVLLPGTASAALLRERRYIGLGFAFSHLVHAVLIYAYGRLAPEFWPSRSGLANVPGTIGYAFLLAMTITSFKPVARRMSATAWKRLHTAGMWVLAAVFALSYFKRIPMNPAYALPFALLTAAVAIRALGKLAQANKRRQRDARAHTAVLRSS</sequence>
</entry>
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            <authorList>
                <person name="Kobayashi D.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </location>
    </feature>
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        <location>
            <begin position="34"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN58629.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="541" mass="56037" checksum="9E12B99C8375594B" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ52</accession>
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    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
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    </gene>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="57" mass="5900" checksum="050B2755233F1C6E" modified="2016-02-17" version="1">MAFAPKELEEIAADFGGRFHAWGKIRLVGSGALDRTHATTMGASTGTGNPGPESRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJE3</accession>
    <name>A0A0S2DJE3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_20480</name>
        <name evidence="5" type="ORF">FE772_16420</name>
        <name evidence="3" type="ORF">GLE_3320</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
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    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000062">
        <property type="protein sequence ID" value="OPD62061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948206.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000062.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3320"/>
    <dbReference type="EnsemblBacteria" id="ALN58666">
        <property type="protein sequence ID" value="ALN58666"/>
        <property type="gene ID" value="GLE_3320"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62061">
        <property type="protein sequence ID" value="OPD62061"/>
        <property type="gene ID" value="BV903_20480"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3320"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3270"/>
    <dbReference type="OMA" id="KKEGKCG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595238" evidence="2">
        <location>
            <begin position="30"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD62061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="124" mass="12090" checksum="C341FD99F8C54B7C" modified="2016-02-17" version="1">MSKKINKPVALALGATLLGGLSLSASAFAMSDLSQGYMLGAQQAQTAEKAADAKATDAKKAEGSCGAKKAEGSCGGDKKKAEGSCGGDKKKAEGSCGGDKKKADAKGKKAGEGKCGEGKCGGSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJH9</accession>
    <name>A0A0S2DJH9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FE772_15390</name>
        <name evidence="9" type="ORF">GLE_3084</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948030.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3084"/>
    <dbReference type="EnsemblBacteria" id="ALN58431">
        <property type="protein sequence ID" value="ALN58431"/>
        <property type="gene ID" value="GLE_3084"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3084"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3043"/>
    <dbReference type="OMA" id="AFPRFYI"/>
    <dbReference type="OrthoDB" id="514956at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726669" evidence="6">
        <location>
            <begin position="34"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="65"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="7">
        <location>
            <begin position="279"/>
            <end position="759"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN58431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW26819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="766" mass="83846" checksum="29EFC6431B391EF7" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJJ3</accession>
    <name>A0A0S2DJJ3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3462</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58807">
        <property type="protein sequence ID" value="ALN58807"/>
        <property type="gene ID" value="GLE_3462"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3462"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3410"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="40" mass="4950" checksum="8B32D0A3F3481223" modified="2016-02-17" version="1">MSRHWHWCLRVCGYDDRSTRNRSAASTHRQRQHRCRDLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJM6</accession>
    <name>A0A0S2DJM6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Riboflavin biosynthesis protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="12">Riboflavin kinase</fullName>
                <ecNumber evidence="12">2.7.1.26</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="12">Flavokinase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="12">FMN adenylyltransferase</fullName>
                <ecNumber evidence="12">2.7.7.2</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="12">FAD pyrophosphorylase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="12">FAD synthase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="15" type="primary">ribF</name>
        <name evidence="15" type="ORF">GLE_3287</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 12">
            <text>ATP + FMN + H(+) = diphosphate + FAD</text>
            <dbReference type="Rhea" id="RHEA:17237"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="2.7.7.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>ATP + riboflavin = ADP + FMN + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14357"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57986"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 12">Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 12">Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the ribF family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.26" evidence="12"/>
    <dbReference type="EC" id="2.7.7.2" evidence="12"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3287"/>
    <dbReference type="EnsemblBacteria" id="ALN58633">
        <property type="protein sequence ID" value="ALN58633"/>
        <property type="gene ID" value="GLE_3287"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3287"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3239"/>
    <dbReference type="OMA" id="HRGHQAI"/>
    <dbReference type="UniPathway" id="UPA00276">
        <property type="reaction ID" value="UER00406"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00277">
        <property type="reaction ID" value="UER00407"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003919">
        <property type="term" value="F:FMN adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008531">
        <property type="term" value="F:riboflavin kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006747">
        <property type="term" value="P:FAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009398">
        <property type="term" value="P:FMN biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02064">
        <property type="entry name" value="FAD_synthetase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015864">
        <property type="entry name" value="FAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023468">
        <property type="entry name" value="Riboflavin_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002606">
        <property type="entry name" value="Riboflavin_kinase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015865">
        <property type="entry name" value="Riboflavin_kinase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023465">
        <property type="entry name" value="Riboflavin_kinase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749">
        <property type="entry name" value="PTHR22749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06574">
        <property type="entry name" value="FAD_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01687">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004491">
        <property type="entry name" value="FAD_Synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00904">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82114">
        <property type="entry name" value="SSF82114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00083">
        <property type="entry name" value="ribF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 12" id="KW-0274">FAD</keyword>
    <keyword evidence="6 12" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 12" id="KW-0288">FMN</keyword>
    <keyword evidence="12" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12 15" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Flavokinase" evidence="14">
        <location>
            <begin position="166"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="300"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR004491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ALN58633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="319" mass="34570" checksum="A61CC49A9F054144" modified="2016-02-17" version="1">MVCIGAFDGLHLGHRALVRHTVARARALGVPAVALSFEPLPREFFAPAAPPPRLLLPRAKAEGLLALDADQVGLLRFNGELSRWSGEEFVQRVLVEQLAAREVWVGPQFRFGKARGGDIALLRRMGEAAGFGAHEIEPVHLDGERVSSTRIREILLAGDFAAAARLLGRPYAIGGHVVRGRQLGRTLGFPTANLRFGGKTPALSGIYATWVHGIGERPWSSVSSLGTRPTVAGVEPLLEAHLFDFDGDLYGRRIEVEFVAHLRAELKFPDLATLTQQMHRDAAQARQSLALDAQRRQLHPALPPDPLRASGADAAETTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJT6</accession>
    <name>A0A0S2DJT6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribonuclease T</fullName>
            <ecNumber evidence="4">3.1.13.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Exoribonuclease T</fullName>
            <shortName evidence="4">RNase T</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">rnt</name>
        <name evidence="7" type="ORF">FE772_16435</name>
        <name evidence="6" type="ORF">GLE_3323</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="4">Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RNase T family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.-" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948208.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3323"/>
    <dbReference type="EnsemblBacteria" id="ALN58669">
        <property type="protein sequence ID" value="ALN58669"/>
        <property type="gene ID" value="GLE_3323"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3323"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3273"/>
    <dbReference type="OMA" id="CYMVNHL"/>
    <dbReference type="OrthoDB" id="1985371at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016896">
        <property type="term" value="F:exoribonuclease activity, producing 5'-phosphomonoesters"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00157">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005987">
        <property type="entry name" value="RNase_T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30231:SF2">
        <property type="entry name" value="PTHR30231:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01298">
        <property type="entry name" value="RNaseT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Exonuclease" evidence="5">
        <location>
            <begin position="28"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="4">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="33"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="site" description="Important for substrate binding and specificity" evidence="4">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate binding and specificity" evidence="4">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate binding and specificity" evidence="4">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW26989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="215" mass="22985" checksum="55086D368FDB5CA5" modified="2016-02-17" version="1">MIDPGPASSAAPAAPVPATLATRFRGYLPVVVDVETGGFDWNKHALLEIAVQPIELDGDGRLVPGEVASSHVVPAAGTLIDPKSLEVTGIDIDHPFRDAKPERQALEAVFAPVREAVKRHGCQRAILVGHNAHFDLNFLNAAVARSGHKRNPFHPFSVFDTVTLAGVAYGQTVLARAVQAAGFVWNGEEAHSAVYDTERTAELFCKIVNAWPARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJZ3</accession>
    <name>A0A0S2DJZ3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type IV pilin protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Type IV pilus assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pilE</name>
        <name evidence="3" type="ORF">FE772_17820</name>
        <name evidence="2" type="ORF">GLE_3621</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057950210.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3621"/>
    <dbReference type="EnsemblBacteria" id="ALN58965">
        <property type="protein sequence ID" value="ALN58965"/>
        <property type="gene ID" value="GLE_3621"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3621"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3565"/>
    <dbReference type="OMA" id="ERSHTTN"/>
    <dbReference type="OrthoDB" id="1857712at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043683">
        <property type="term" value="P:type IV pilus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000983">
        <property type="entry name" value="Bac_GSPG_pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031982">
        <property type="entry name" value="PilE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16732">
        <property type="entry name" value="ComP_DUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00813">
        <property type="entry name" value="BCTERIALGSPG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="152" mass="16189" checksum="65176585D3C6C0A5" modified="2016-02-17" version="1">MSVQGFAELHGHGRARRQAGFTLVELMIAVAIVGILAAIAYPAYDDSVRKGRRAQAKADLVELAQRAERFYTLNNTYAGFWGSVPSGDKRSPRTGNAFYLLERSSGDTDANAFTLSATPTGAQVADSGCGTLSINQAGVRSISGSMEPARCW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK77</accession>
    <name>A0A0S2DK77_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Enoyl-CoA hydratase/isomerase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_16335</name>
        <name evidence="2" type="ORF">GLE_3302</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
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        <property type="protein sequence ID" value="ALN58648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW26971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948191.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3302"/>
    <dbReference type="EnsemblBacteria" id="ALN58648">
        <property type="protein sequence ID" value="ALN58648"/>
        <property type="gene ID" value="GLE_3302"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3302"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3252"/>
    <dbReference type="OMA" id="WFMSSFL"/>
    <dbReference type="OrthoDB" id="1498685at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="252" mass="26996" checksum="016CC3ABC5C15A94" modified="2016-02-17" version="1">MNCVETQTHGDIVEIKLARAPVNALNPALCNAAREAVEHAIGHGAQGIVLSGGPKVFSAGLDVPYLLSLGDQRDHLLLAWQSFFGLARTLASAQVPVVAAIAGHAPAGGCVLTLCCDYRVMAAGAYRIGLNETQVGLVAPEGIQRLMRRVVGTYRAERLLVAGAMVDADTALRIGLVDELVEIEQVAAHAREWLQQLLSLPRSAMLQTRALARADLIEALRPEHIELDRFVDSWYSPDTQAALQALVAKLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK84</accession>
    <name>A0A0S2DK84_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_18170</name>
        <name evidence="3" type="ORF">GLE_3686</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948473.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3686"/>
    <dbReference type="EnsemblBacteria" id="ALN59030">
        <property type="protein sequence ID" value="ALN59030"/>
        <property type="gene ID" value="GLE_3686"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3686"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3630"/>
    <dbReference type="OrthoDB" id="1278405at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242207" evidence="2">
        <location>
            <begin position="29"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="442"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="832" mass="89104" checksum="F80DE4014DA2FE49" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKE3</accession>
    <name>A0A0S2DKE3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3671</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3671"/>
    <dbReference type="EnsemblBacteria" id="ALN59015">
        <property type="protein sequence ID" value="ALN59015"/>
        <property type="gene ID" value="GLE_3671"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3671"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3614"/>
    <dbReference type="OMA" id="HQRWATG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="513" mass="54971" checksum="EEC8C626521D7C56" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKJ8</accession>
    <name>A0A0S2DKJ8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histidine kinase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_17470</name>
        <name evidence="2" type="ORF">GLE_3549</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW27157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948373.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3549"/>
    <dbReference type="EnsemblBacteria" id="ALN58893">
        <property type="protein sequence ID" value="ALN58893"/>
        <property type="gene ID" value="GLE_3549"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3549"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3493"/>
    <dbReference type="OMA" id="CEGYSNE"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="1">
        <location>
            <begin position="148"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="238" mass="26504" checksum="14631B678CFFB929" modified="2016-02-17" version="1">MSDPSDLRTLYQELLQRLQRNEREFRRLGRAVWRVQEDERRRIARDLHDGVGQNLTALKLRLHDIQSALEPQQTALREGLAQALALCADTLEDTRELSRLLRPPILDDLGLEAALRWLARSHDGRDGARVELELGALPELDGELQTVLFRTAQEALANAARHAQARRVRIGLHCRGDELHLDVRDDGRGCDPVAALASGGNGLGGMRERLRLYGGRLEIASAPGAGLRLSARLPLDYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKK9</accession>
    <name>A0A0S2DKK9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3742</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59086">
        <property type="protein sequence ID" value="ALN59086"/>
        <property type="gene ID" value="GLE_3742"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3742"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="38" mass="3758" checksum="57A6D606E78D3B62" modified="2016-02-17" version="1">MAAAGVEHGRGLGAGTRDPGPGTGSLGFLDLPRLPARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKL1</accession>
    <name>A0A0S2DKL1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Peptidase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="11">Peptidase, family M13</fullName>
            <ecNumber evidence="11">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FE772_17155</name>
        <name evidence="11" type="ORF">GLE_3486</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M13 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="11"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58831">
        <property type="protein sequence ID" value="ALN58831"/>
        <property type="gene ID" value="GLE_3486"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3486"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3431"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08662">
        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="PTHR11733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00786">
        <property type="entry name" value="NEPRILYSIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242209" evidence="8">
        <location>
            <begin position="23"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M13_N" evidence="10">
        <location>
            <begin position="69"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M13" evidence="9">
        <location>
            <begin position="497"/>
            <end position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN58831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW27107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="701" mass="76110" checksum="BFAEC12053D44472" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKL3</accession>
    <name>A0A0S2DKL3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_17800</name>
        <name evidence="2" type="ORF">GLE_3617</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948419.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58961">
        <property type="protein sequence ID" value="ALN58961"/>
        <property type="gene ID" value="GLE_3617"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3617"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3561"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="79" mass="8668" checksum="AD359CE0AE89D30D" modified="2016-02-17" version="1">MTPSPAPTPPPKSGLLRREALGFWFLGLGALGLVRAWMRATRHGGFETDTVSLLWLIGSAVLVVISAARIWRTLRSARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKU0</accession>
    <name>A0A0S2DKU0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Non-homologous end joining protein Ku</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ku</name>
        <name evidence="6" type="ORF">BV903_07540</name>
        <name evidence="7" type="ORF">FE772_18215</name>
        <name evidence="5" type="ORF">GLE_3697</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer. Interacts with LigD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prokaryotic Ku family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000014">
        <property type="protein sequence ID" value="OPD64608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948480.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000014.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3697"/>
    <dbReference type="EnsemblBacteria" id="ALN59041">
        <property type="protein sequence ID" value="ALN59041"/>
        <property type="gene ID" value="GLE_3697"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64608">
        <property type="protein sequence ID" value="OPD64608"/>
        <property type="gene ID" value="BV903_07540"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3697"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3641"/>
    <dbReference type="OMA" id="IRYRKVC"/>
    <dbReference type="OrthoDB" id="1724780at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00789">
        <property type="entry name" value="KU_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01875">
        <property type="entry name" value="Prokaryotic_Ku"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006164">
        <property type="entry name" value="Ku70/Ku80_beta-barrel_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009187">
        <property type="entry name" value="Prok_Ku"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016194">
        <property type="entry name" value="SPOC-like_C_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41251">
        <property type="entry name" value="PTHR41251"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02735">
        <property type="entry name" value="Ku"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006493">
        <property type="entry name" value="Prok_Ku"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00559">
        <property type="entry name" value="Ku78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100939">
        <property type="entry name" value="SSF100939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02772">
        <property type="entry name" value="Ku_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ku" evidence="4">
        <location>
            <begin position="53"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="267"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="280"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD64608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW27282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="303" mass="33750" checksum="CE1A41CF6CAEBD94" modified="2016-02-17" version="1">MARPIWTGTISFGLLNIPVKLMAGERRVDLHFRMLDSRNKAPIRYERVNEETGEEVPWKEIVKAFEYDKGSYVVLEAADIAAAAPDHTETVDIDAFVDAAQIGSEYYDKPYILEPGKKAEKGYVLLREVLEKTGKVGIGRVVIRTREYLAALAPKGNALVLLILRYAQELVDPEDYKLPEGGLAKWKISAREVEMAQQLIESMTAPWKPESYKDDFRQRLHKVIEQRVKAKKVVRGKQADESKLPENAATNVIDFAELLKRSLAKKGAAAPAKAAGKRAAKTAKAAKKKPAKPAARSRATKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKW9</accession>
    <name>A0A0S2DKW9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GumN protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">TraB/GumN family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_09095</name>
        <name evidence="4" type="ORF">FE772_17530</name>
        <name evidence="2" type="ORF">GLE_3560</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000019">
        <property type="protein sequence ID" value="OPD64326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948382.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3560"/>
    <dbReference type="EnsemblBacteria" id="ALN58904">
        <property type="protein sequence ID" value="ALN58904"/>
        <property type="gene ID" value="GLE_3560"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64326">
        <property type="protein sequence ID" value="OPD64326"/>
        <property type="gene ID" value="BV903_09095"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3560"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3504"/>
    <dbReference type="OMA" id="FVIANER"/>
    <dbReference type="OrthoDB" id="1991552at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010916">
        <property type="entry name" value="TonB_box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002816">
        <property type="entry name" value="TraB/PrgY/GumN_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01963">
        <property type="entry name" value="TraB_PrgY_gumN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00430">
        <property type="entry name" value="TONB_DEPENDENT_REC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595772" evidence="1">
        <location>
            <begin position="19"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="332" mass="35950" checksum="00AE28BAB535E7ED" modified="2016-02-17" version="1">MRRALTALALLALLPAAAAQTPTPPPAGDIRDLDTLVVTGEQPGPGLWKVTRGGHVLWILGTVSPLPKDMTWLSRQVEATIADSQEVIAPPSVSLGTELGMFRTMMLIPTALKARKNPDGKTLQDVVPADLYARWSALKARYIGRDGGVEKWRPIFAAQELYEAAIKQSGLSLKGVVQPVVEKAAKQHGVPVTEARVTLKIDDPKATLKEFADSAMDDRECFAKTLSRIETDLEAMRARGNAWAVGDIATLRTLPQGDQYRTCLEALAATGVARRLNLGDLRQRVTANWLERAQEAIAKNNSTFASLPVADLLESGGLLDKLRDAGYTVEDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLD2</accession>
    <name>A0A0S2DLD2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Corrinoid adenosyltransferase</fullName>
            <ecNumber evidence="4">2.5.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Cob(II)alamin adenosyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Cob(II)yrinic acid a,c-diamide adenosyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Cobinamide/cobalamin adenosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BV903_19070</name>
        <name evidence="9" type="ORF">FE772_19185</name>
        <name evidence="7" type="ORF">GLE_3907</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2 ATP + 2 cob(II)alamin + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)alamin + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate</text>
            <dbReference type="Rhea" id="RHEA:28671"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="2.5.1.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2 ATP + 2 cob(II)yrinate a,c diamide + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)yrinate a,c-diamide + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate</text>
            <dbReference type="Rhea" id="RHEA:11528"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:58503"/>
            <dbReference type="ChEBI" id="CHEBI:58537"/>
            <dbReference type="EC" id="2.5.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 2/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the Cob(I)alamin adenosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.17" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000054">
        <property type="protein sequence ID" value="OPD62328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948637.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000054.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3907"/>
    <dbReference type="EnsemblBacteria" id="ALN59249">
        <property type="protein sequence ID" value="ALN59249"/>
        <property type="gene ID" value="GLE_3907"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62328">
        <property type="protein sequence ID" value="OPD62328"/>
        <property type="gene ID" value="BV903_19070"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3907"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3844"/>
    <dbReference type="OMA" id="HQACTVV"/>
    <dbReference type="OrthoDB" id="1401910at2"/>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00233"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008817">
        <property type="term" value="F:cob(I)yrinic acid a,c-diamide adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016030">
        <property type="entry name" value="CblAdoTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036451">
        <property type="entry name" value="CblAdoTrfase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029499">
        <property type="entry name" value="PduO-typ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12213">
        <property type="entry name" value="PTHR12213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01923">
        <property type="entry name" value="Cob_adeno_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89028">
        <property type="entry name" value="SSF89028"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00636">
        <property type="entry name" value="PduO_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cob_adeno_trans" evidence="6">
        <location>
            <begin position="8"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD62328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW27444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="184" mass="20120" checksum="0C7B5DEDF2BBF840" modified="2016-02-17" version="1">MGNRLSKIYTRTGDDGSTGLGDGSRTGKDSARVGAYGTVDEANSTIGLILAAELPDEVREQLVSIQHQMFDLGAELCIPGHAAIFAADIDRLEHWLDAHNEHLPPLKEFILPAGGEAAARCHIARTVVRRAEREAVALARVEDIRPEAVRYLNRLSDLLFVIARVLARAGGHGEVTWNHERRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLF3</accession>
    <name>A0A0S2DLF3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Universal stress protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Universal stress protein family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_19635</name>
        <name evidence="2" type="ORF">GLE_4004</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948706.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59346">
        <property type="protein sequence ID" value="ALN59346"/>
        <property type="gene ID" value="GLE_4004"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4004"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3941"/>
    <dbReference type="OMA" id="AYGHPRW"/>
    <dbReference type="OrthoDB" id="2040681at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="196"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="273" mass="29694" checksum="91E64CAEA51715D8" modified="2016-02-17" version="1">MYKDLLLPMMSGRIPDPALQAARTLCKQWNARLTVLVGVSHAQPEPMAWEYFSGSLGSTMQECAETTVRAMAEAADARLREAGIEYEICRTSLSWATPAQMCMEHARLADVILLEADPPGALHPHRLFGELAASGGRPILSLPTGSGAIAMERALIAWNATREATRAIHDAIPWLQRMRAVEILVVEDGRFQAHAQDALICAHLRRHGVEAQIVRRSSSGGDAGQTIRVYAAESRTDLIVAGAYGHPRVMEMVFGGATRSLLANSPAPVFFSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLX5</accession>
    <name>A0A0S2DLX5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_11715</name>
        <name evidence="3" type="ORF">GLE_4366</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000028">
        <property type="protein sequence ID" value="OPD63714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948996.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000028.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59707">
        <property type="protein sequence ID" value="ALN59707"/>
        <property type="gene ID" value="GLE_4366"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63714">
        <property type="protein sequence ID" value="OPD63714"/>
        <property type="gene ID" value="BV903_11715"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4366"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4305"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595419" evidence="2">
        <location>
            <begin position="25"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD63714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="60" mass="5633" checksum="320C10FECD1E4175" modified="2016-02-17" version="1">MKIDLRTAAYASIVLGALSLAACASKGETTPDAPASSSSTPSSAPADAATAPPPTSGDGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM33</accession>
    <name>A0A0S2DM33_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_20760</name>
        <name evidence="1" type="ORF">GLE_4239</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948895.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59580">
        <property type="protein sequence ID" value="ALN59580"/>
        <property type="gene ID" value="GLE_4239"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4239"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4180"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="179" mass="18258" checksum="CA26A6E54227731A" modified="2016-02-17" version="1">MSARSSLPSPAWAARARPLRAGAAAAALALALCACKPPDIPGPVAETEYKLGAVPESSVGKIKLNYWKLEGPVKAGQPFALGISITNGSEVWLAAGTADSLRLSASWLEPTTYAARAPTVTIERKTGVGSGVSGAEQFTLVAPPAAGRVLLKLVLTDADGTSLEAAGVGPLHYDLTVDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMN4</accession>
    <name>A0A0S2DMN4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE</fullName>
            <ecNumber evidence="6">2.1.1.163</ecNumber>
            <ecNumber evidence="6">2.1.1.201</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">2-methoxy-6-polyprenyl-1,4-benzoquinol methylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Demethylmenaquinone methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 7" type="primary">ubiE</name>
        <name evidence="8" type="ORF">FE772_22080</name>
        <name evidence="7" type="ORF">GLE_4522</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 2-demethylmenaquinol + S-adenosyl-L-methionine = a menaquinol + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42640"/>
            <dbReference type="Rhea" id="RHEA-COMP:9539"/>
            <dbReference type="Rhea" id="RHEA-COMP:9563"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18151"/>
            <dbReference type="ChEBI" id="CHEBI:55437"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.1.1.163"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 2-methoxy-6-all-trans-polyprenyl-1,4-benzoquinol + S-adenosyl-L-methionine = a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:28286"/>
            <dbReference type="Rhea" id="RHEA-COMP:10858"/>
            <dbReference type="Rhea" id="RHEA-COMP:10859"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:84166"/>
            <dbReference type="ChEBI" id="CHEBI:84167"/>
            <dbReference type="EC" id="2.1.1.201"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Quinol/quinone metabolism; menaquinone biosynthesis; menaquinol from 1,4-dihydroxy-2-naphthoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.163" evidence="6"/>
    <dbReference type="EC" id="2.1.1.201" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949119.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4522"/>
    <dbReference type="EnsemblBacteria" id="ALN59863">
        <property type="protein sequence ID" value="ALN59863"/>
        <property type="gene ID" value="GLE_4522"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4522"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4458"/>
    <dbReference type="OMA" id="VRNFENL"/>
    <dbReference type="OrthoDB" id="1431378at2"/>
    <dbReference type="UniPathway" id="UPA00079">
        <property type="reaction ID" value="UER00169"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043333">
        <property type="term" value="F:2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043770">
        <property type="term" value="F:demethylmenaquinone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102094">
        <property type="term" value="F:S-adenosylmethionine:2-demethylmenaquinol methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102955">
        <property type="term" value="F:S-adenosylmethionine:2-demethylmenaquinol-7 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102027">
        <property type="term" value="F:S-adenosylmethionine:2-demethylquinol-8 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009060">
        <property type="term" value="P:aerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01813">
        <property type="entry name" value="MenG_UbiE_methyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004033">
        <property type="entry name" value="UbiE/COQ5_MeTrFase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023576">
        <property type="entry name" value="UbiE/COQ5_MeTrFase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01209">
        <property type="entry name" value="Ubie_methyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01934">
        <property type="entry name" value="MenG_MenH_UbiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51608">
        <property type="entry name" value="SAM_MT_UBIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01183">
        <property type="entry name" value="UBIE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01184">
        <property type="entry name" value="UBIE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="2 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0830">Ubiquinone</keyword>
    <keyword evidence="4 6" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="6">
        <location>
            <begin position="126"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW27932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="254" mass="28585" checksum="61C06F817A9CB6BE" modified="2016-02-17" version="1">MNESKPQTDDTTHFGFRDVPREQKRKLVGEVFSSVAGNYDLMNDLMSLGIHRVWKRYFTATAQVRRGDRVLDLAGGTGDIAALLRDRVGDSGSIVLGDINYDMLKVGRDRMTDRGRVSGFEYVQCNAEALPFPDASFDLVTIAFGLRNVTDKDAALREMLRVLKVGGQARVLEFSEVKAEWFKPIYDFHSFNVLPKLGKLFANDSDSYRYLAESIRKHPPQDELKRMMVDAGFARVDYKNLSAGICAVHTGYKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMP9</accession>
    <name>A0A0S2DMP9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4193</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59535">
        <property type="protein sequence ID" value="ALN59535"/>
        <property type="gene ID" value="GLE_4193"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4193"/>
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    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="99" mass="10776" checksum="974DB48B89AB4A2A" modified="2016-02-17" version="1">MSTYNRPAMPRPILRTHALRHALRGGPRNRRKAGDAGRGRIRDRGQARHGVPGPESDRSPGGEGRPAVERTPEFKASPPDAEAHSEARPHASCRSLTVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMQ6</accession>
    <name>A0A0S2DMQ6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4304</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59645">
        <property type="protein sequence ID" value="ALN59645"/>
        <property type="gene ID" value="GLE_4304"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4304"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4243"/>
    <dbReference type="OMA" id="CNDIDEH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="168" mass="18850" checksum="AE051229464E367A" modified="2016-02-17" version="1">MDMLKELIDLLTCRELDPEELAELVASIENAGDDPDLDWMDDPSPEELIQNAIVFKLVNHLAVGDKIDEVHEQVSDFFAEPLADFPRHANGRGYLPDEYFAWLDPLLAERGKDGGGYRLMLLDDSFSDQLNALLVWRKDTARVLELAGALALSIESSTERSLGHRPVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMR4</accession>
    <name>A0A0S2DMR4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sensor histidine kinase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Two-component system sensor protein</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fimS</name>
        <name evidence="4" type="ORF">FE772_22225</name>
        <name evidence="3" type="ORF">GLE_4554</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4554"/>
    <dbReference type="EnsemblBacteria" id="ALN59895">
        <property type="protein sequence ID" value="ALN59895"/>
        <property type="gene ID" value="GLE_4554"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4554"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4490"/>
    <dbReference type="OMA" id="NSMNTIA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010559">
        <property type="entry name" value="Sig_transdc_His_kin_internal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06580">
        <property type="entry name" value="His_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="His_kinase" evidence="2">
        <location>
            <begin position="162"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="356" mass="38449" checksum="07A3E40150E00DD6" modified="2016-02-17" version="1">MADLRSGTAASEPEPWLPDLCRLPRLVVMLSMAELIVIVLALAPDGSAWNLSRFVSSSAFALWLALAISVLLCVSRRQLSRLPPGLGGFIATATAAAIAAAVAAVTHWIDSVTGVGLIPAGTTFARFVGGTAAIAILAVSVVLRYLYVNDSWKAQVRANARAEVEALQARIKPHFLFNSMNTIAGLVRSDPAVAERAVLDLSDLFRAALGASKSDSSLTEEVELAERYLAIEQLRLGERLRVVWRKREPLPWKMPLPRLVLQPLVENAVLHGISRLPGGGEVEIELTQLSDHLLLRIRNPAPAPAEARAGARHAQHSIGQRLRYAYGPTARMTAGWDGGYYLCELHVPTGVEAQSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN27</accession>
    <name>A0A0S2DN27_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Transporter, major facilitator family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_22855</name>
        <name evidence="7" type="ORF">GLE_4697</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949244.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60038">
        <property type="protein sequence ID" value="ALN60038"/>
        <property type="gene ID" value="GLE_4697"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4697"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4631"/>
    <dbReference type="OMA" id="CKPRMLE"/>
    <dbReference type="OrthoDB" id="806182at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="273"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="330"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="362"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="391"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="21"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN60038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW28059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="423" mass="43935" checksum="02BC37BC7503A4EF" modified="2016-02-17" version="1">MSANAAPASAVRPLWQGRAWVLAGIVLSAFTLRTAVTSLTPLLDALGREFGFGATMTGVFGMVPTAAFALFGVATPALAHRIGLERAALLAMAVAALGLLARGFVGDTWQLLAANAVALAGMGIGNVVLPPLVKRYFGDRVGAVSTAYITVLQLGTILPALAAVPLAQAAGWRISLASWSLVAAAAALPWISVLWMEARGRSAQARALAQAHDRAVAGGDEAPELPAAAARGKVWRSPVAWGMTLMFGMTSLVTYSMFTWLPKLLVEAGGSPALGGAMVALFSTLGMISALTMPALAVRIANPFPIVLACVLCYLGGFAGLLLAPMHGTFLWVALIGLGPSTFPLALTLINLRTRTPAGSAALSGFMQGLGYTLSCLGPLTFGWLHELSHGWVWPFAMLGGCLLVLIAGGRMACQPRYLEDSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN93</accession>
    <name>A0A0S2DN93_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">R body protein RebB-like protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">RebA protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rebA</name>
        <name evidence="2" type="ORF">BV903_15750</name>
        <name evidence="4" type="ORF">D9T17_06035</name>
        <name evidence="3" type="ORF">FE772_22720</name>
        <name evidence="1" type="ORF">GLE_4663</name>
    </gene>
    <organism evidence="1 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 5">C3</strain>
        </source>
    </reference>
    <reference evidence="2 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">OH11</strain>
        </source>
    </reference>
    <reference evidence="3 8" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000041">
        <property type="protein sequence ID" value="OPD62929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000019">
        <property type="protein sequence ID" value="ROU07766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949220.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60004">
        <property type="protein sequence ID" value="ALN60004"/>
        <property type="gene ID" value="GLE_4663"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62929">
        <property type="protein sequence ID" value="OPD62929"/>
        <property type="gene ID" value="BV903_15750"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4663"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4599"/>
    <dbReference type="OMA" id="CQVCQVN"/>
    <dbReference type="OrthoDB" id="2059941at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021070">
        <property type="entry name" value="Killing_trait_RebB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11747">
        <property type="entry name" value="RebB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD62929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROU07766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="112" mass="11649" checksum="AA028995319DC6D2" modified="2016-02-17" version="1">MAYPTAVNNQITDAVTQSNVKVIAEGPAFAMGSMYQASAHSTGILFENAIASQQQQTSLSQAATNQGVMQIYTVDTTAAAGATEKIAQTGVADNLTSLMTVLQSFKSNPYGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNG3</accession>
    <name>A0A0S2DNG3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4676</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60017">
        <property type="protein sequence ID" value="ALN60017"/>
        <property type="gene ID" value="GLE_4676"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4676"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4612"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="43" mass="4717" checksum="C04BA4863B4159D2" modified="2016-02-17" version="1">MPAAGLALAGEEQSEAVIRAHARCLIQRMRDAVRERAAKNIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNI6</accession>
    <name>A0A0S2DNI6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Excalibur domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_4728</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949266.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4728"/>
    <dbReference type="EnsemblBacteria" id="ALN60069">
        <property type="protein sequence ID" value="ALN60069"/>
        <property type="gene ID" value="GLE_4728"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4728"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4662"/>
    <dbReference type="OMA" id="SMHRIAI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008613">
        <property type="entry name" value="Excalibur_Ca-bd_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05901">
        <property type="entry name" value="Excalibur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00894">
        <property type="entry name" value="Excalibur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595448" evidence="2">
        <location>
            <begin position="30"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Excalibur" evidence="3">
        <location>
            <begin position="94"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="130" mass="13298" checksum="4EF18BE9D50F7799" modified="2016-02-17" version="1">MKPIHERRRRTALAALLAVLAAAPPAAPAHGGGLDRHGCHHDRRNGGYHCHRGSAPATAALDRGGSALQPPGRRGLRPLPVDAAGGGNTHGATAYPNCAAARAAGAAPLLRGDPGYSRRLDRDGDGRACE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNP2</accession>
    <name>A0A0S2DNP2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_4839</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949351.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4839"/>
    <dbReference type="EnsemblBacteria" id="ALN60180">
        <property type="protein sequence ID" value="ALN60180"/>
        <property type="gene ID" value="GLE_4839"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4839"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4769"/>
    <dbReference type="OMA" id="VNLSDMY"/>
    <dbReference type="OrthoDB" id="1200399at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595331" evidence="2">
        <location>
            <begin position="37"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="73"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="383" mass="39773" checksum="DC2A9537E66BF27E" modified="2016-02-17" version="1">MNRPLRTLAPLPRAALSAAVAGLVLFAATGCGRSEAETAQAPATPEVLTVKAKAAEPVYDLSLPARAQAGESAALYARATGFVSERKAELGDKVGAGQVLATISAPEIDQAVREARAVLAQANADEELAKVNYQRAQQLINTGAVSKEYFSDRKGSYDVAVAARNAAQARLTSALERQSFTAVRAPFAGVVVARNIERGDRVVGDSATATVPMFEVAVLDPLRVVVDVPQNVSLQISNGLQAEVSFPELPGQVFQAEVARSARALSRDAGVMRTELRLPNPDGRIPAGMVGSARLHLPRAATAVVLPVSTVVQRAAGTQVATVTPGSTLTYRDVTVGRNLGNEIEVLTGIAPGDTVVLAPNALLAEGNKVSAKALPPPAAKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNY5</accession>
    <name>A0A0S2DNY5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Transporter, major facilitator family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_24320</name>
        <name evidence="7" type="ORF">GLE_5017</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5017"/>
    <dbReference type="EnsemblBacteria" id="ALN60358">
        <property type="protein sequence ID" value="ALN60358"/>
        <property type="gene ID" value="GLE_5017"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5017"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4945"/>
    <dbReference type="OMA" id="TVCVWTL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="117"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="311"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="348"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="25"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN60358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW28307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="409" mass="42240" checksum="42C2F3E46099AFC4" modified="2016-02-17" version="1">MNAAATPAASVAAGPVLDEAARKRALNGLLVYTFFMVAGFAMLMPLVAVHYVDGVGMAAAAVGLALAVRQLLQQGLALLGGMLSDRYGARRMICLGVLLRAAGFASLAFAADLPLLLLAMALSALGGAMFEAPYQASIAALTDAQSRPRYYAISNWVSGVATTLGPLLGVALLRFDFRIVCLAAAACFALNFVIALRLLPKFEMPPQPPPLRHGLGLVRANRAFATLVGWLMLYWFLAVQINISFPLLAQKLAGSVDGVGAMFALSAGITVALQYGLVRWLERRLSAAQVLVLGVALMALSTGAIAFAGSYAGLLACVAGYALGAVMTRPTQQTLIAGLADARALGTFLGVSSLSLAVGGGLGNIAGGWLMDVAAATQRPWLPWAVFCAVGLSSALGLHLALRGRAAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNY8</accession>
    <name>A0A0S2DNY8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DGPF domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_5086</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YciI family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5086"/>
    <dbReference type="EnsemblBacteria" id="ALN60427">
        <property type="protein sequence ID" value="ALN60427"/>
        <property type="gene ID" value="GLE_5086"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5086"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5013"/>
    <dbReference type="OMA" id="AMGKFNE"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII" evidence="2">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="138" mass="14895" checksum="B7D4425A72061615" modified="2016-02-17" version="1">MLIVKATPDSEAGVMPGTELLAAMGAYNEELVRAGVLLAGEGLHPSARGARVYFDGRARRVADGPFDAPGELIAGFWLIQARSLEEAVEWVKRVPNPDGAQSQIEIRRVFDAADFGEALTPELQATEARLREQVGGRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP11</accession>
    <name>A0A0S2DP11_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MBL fold metallo-hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Metallo-beta-lactamase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_23720</name>
        <name evidence="2" type="ORF">GLE_4884</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949389.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4884"/>
    <dbReference type="EnsemblBacteria" id="ALN60225">
        <property type="protein sequence ID" value="ALN60225"/>
        <property type="gene ID" value="GLE_4884"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4884"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4815"/>
    <dbReference type="OMA" id="ICADERQ"/>
    <dbReference type="OrthoDB" id="1152855at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="72"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="268" mass="30053" checksum="223BBDF93C239214" modified="2016-02-17" version="1">MPCPICETCGTQFAESAAPPTHCPVCEDERQYVGWNGQRWTTMESLAQRHRLRIDEDAGVLSLSMSPGFAIDQRAMFLPTGAGNLLWETLSLVTDEAVRALRARGGVDLIAISHPHFYASMVEWSRAFGDVPIYLHEADREWVQRPSPAIRWWHGDELALSDDVVLIRCGGHFDGSTALHWRRDGARGAALFPGDALQVVSDRRHTTFMYSYPNYIPMKPADVRAMRERIERFAFEDVYGYSLGRNILGGGRAAVDASFQRYFDAIAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP90</accession>
    <name>A0A0S2DP90_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Cell division ATP-binding protein FtsE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">ftsE</name>
        <name evidence="10" type="ORF">GLE_4915</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer. Forms a membrane-associated complex with FtsX.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
            <orientation evidence="7">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4915"/>
    <dbReference type="EnsemblBacteria" id="ALN60256">
        <property type="protein sequence ID" value="ALN60256"/>
        <property type="gene ID" value="GLE_4915"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4915"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4845"/>
    <dbReference type="OMA" id="PTRGHID"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </evidence>
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            <dbReference type="PROSITE" id="PS50893"/>
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    <evidence type="ECO:0000313" key="10">
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            <dbReference type="EMBL" id="ALN60256.1"/>
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            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
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    <sequence length="272" mass="29354" checksum="FBCB3F7A1CB0E384" modified="2016-02-17" version="1">MRCSGSSRARPILDEAAPAAARTQTEPPRRTPMSSGDSLCDTSAMTVLRFDNVSKRYSSGHEALSEVSFEVAAGEMLFVTGHSGAGKSTLLKLIHLSERPSRGAVVFADKNLLKVRGRRIALHRRDVGVVFQDHRLLADRSVADNVALPLLLRGLRRGDIGRRVRSALEKVGLGARATALPGELSAGEQQRVGIARAIIGEPRLLVADEPTGNLDPTLSAEIMALFQSLPERGTSVLIASHDLALVKRMKKRVLVLNHGRLVDDIAPEDLAE</sequence>
</entry>
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    <accession>A0A0S2DPB7</accession>
    <name>A0A0S2DPB7_LYSEN</name>
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        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_24490</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
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    <dbReference type="EnsemblBacteria" id="ALN60394">
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        <location>
            <begin position="4139"/>
            <end position="4186"/>
        </location>
    </feature>
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        <source>
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        <source>
            <dbReference type="EMBL" id="ALN60394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28336.1"/>
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    </evidence>
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        <source>
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        <source>
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        </source>
    </evidence>
    <sequence length="4874" mass="527907" checksum="C33B983E9F87E5AB" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPC8</accession>
    <name>A0A0S2DPC8_LYSEN</name>
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            <fullName evidence="3">Dipeptidyl peptidase IV</fullName>
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        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">GLE_4950</name>
    </gene>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.-.-" evidence="3"/>
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    </dbReference>
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        <location>
            <begin position="126"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="1">
        <location>
            <begin position="558"/>
            <end position="752"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="753" mass="82968" checksum="D735FE1E1869973D" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPE1</accession>
    <name>A0A0S2DPE1_LYSEN</name>
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        <submittedName>
            <fullName evidence="1">4-oxalocrotonate tautomerase</fullName>
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    </protein>
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        <name evidence="1" type="primary">xylH</name>
        <name evidence="3" type="ORF">D9T17_04970</name>
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    </gene>
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        <name type="scientific">Lysobacter enzymogenes</name>
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            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">OH11</strain>
        </source>
    </reference>
    <reference evidence="2 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.3.2.-" evidence="1"/>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="ROU08266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="protein sequence ID" value="ALN60249"/>
        <property type="gene ID" value="GLE_4908"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014347">
        <property type="entry name" value="Tautomerase/MIF_sf"/>
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        <property type="entry name" value="SSF55331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROU08266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="136" mass="15098" checksum="BBE98D1022DD37D2" modified="2016-02-17" version="1">MPHLNLQISGPADPALARRASALVADLTVETLGKPRELIAIEVRFVDRALWFVDGRSLEELGRNSFFLDISITDETNTKDEKARFIERAYAQLSALIGEVHEVSYIHVVDARAAAYGYGGATQERRYQAARIAAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPF5</accession>
    <name>A0A0S2DPF5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cupin domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4924</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949419.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4924"/>
    <dbReference type="EnsemblBacteria" id="ALN60265">
        <property type="protein sequence ID" value="ALN60265"/>
        <property type="gene ID" value="GLE_4924"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4924"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4853"/>
    <dbReference type="OMA" id="KMNDGPT"/>
    <dbReference type="OrthoDB" id="1928636at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595933" evidence="1">
        <location>
            <begin position="21"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin_2" evidence="2">
        <location>
            <begin position="59"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="142" mass="14565" checksum="033256ADD21AF7E2" modified="2016-02-17" version="1">MSPRLSALALFLAAACPVAAAAHGAAPAAGHAAPAPVVTEVMRKPLPDYPGKEALMLSVEYPPGGADPVHRHDAHAFVYVVEGAIVMGVAGGKEVELKAGESFYEAPGDLHTVGRNASDKRPAKFVVVLLKDAGKPALMPVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPY3</accession>
    <name>A0A0S2DPY3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5303</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5303"/>
    <dbReference type="EnsemblBacteria" id="ALN60644">
        <property type="protein sequence ID" value="ALN60644"/>
        <property type="gene ID" value="GLE_5303"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5303"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5221"/>
    <dbReference type="OMA" id="WNRNLML"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="38"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="440" mass="48468" checksum="05BBC7D0A3D85910" modified="2016-02-17" version="1">MADLLPPPMHSDETPTYYTATKKYDLRFPSLEQDIDADVVVIGGGFSGINTALELAERGVTDVVVLEARHLGFGGTGRNGGQIMAGIGHDLDAIKKDVGEDGVRAIFAISDQGAAIIQSRIRRYGIDADFHHGYGYLGFNARQAKTLRAWEKEFKALSPDQDIRYLEGAEVRSIIGSQAYGSALLHMGGGHVHSLNLLLGEAQALAGHGARIFEHSPALQVEYGERIRVRTAKGSVRAQKLLWACDSFLNGLEPELHRSTINTYAFQLMTEPLPDELIERISPIRGAYSDIRPVIDYFRVTRENRLLFGSATPIVEHIPRDLKQWNRRLMLKVFPYLKDVAIDLAWGGPMALSPNLFPQIGSLPGRPNAFFVQGYSGFGVTPSHIVCQVLSEGILGGSPRYALLSSVSRASVHAKDQLRPLICTLGKSWHQLSGYWNGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ10</accession>
    <name>A0A0S2DQ10_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Efflux ABC transporter, permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLE_5219</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5219"/>
    <dbReference type="EnsemblBacteria" id="ALN60560">
        <property type="protein sequence ID" value="ALN60560"/>
        <property type="gene ID" value="GLE_5219"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5219"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5137"/>
    <dbReference type="OMA" id="FYRHQTQ"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="293"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="346"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="377"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="9">
        <location>
            <begin position="26"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="322"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN60560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="417" mass="45213" checksum="9C796D2C90ABC277" modified="2016-02-17" version="1">MSRLLAWLPPIWREAVEELWRRRLRTLLTLLGLIFGVGAIVAMQAVGEGSRREALRLVESLGLNNLIVEAKAQQDENSLREIRARSLGLSLADADAALAVVPGAQRYAAEKPIRTHSVFSDDGRSDAQASGVSPDYFQLSSLRVAKGRALTAQDDRALAAVAVLGHQAAADLFPGADPLGRYLKVNHVWLQVVGVLADRDLSKDQFEGVQLGLESNRVYVPLASARARFKFNPQEDEVDRVLLRLGDPSQLAQGARVLSTVLGQRHAGSADFRLVVPQQLFQQHQKTQRIFRVVMGAIAGVSLLVGGIGIMNIMLANVLERRREIGLLRALGARRRDVVAQFLREATVICVSGAALGLLFGVLLAYLIAAFAGWQVAWAPIPVLLSATFCAAVGLAFGVYPARQAARLDPIAALRHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQC5</accession>
    <name>A0A0S2DQC5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PspA/IM30 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_00390</name>
        <name evidence="4" type="ORF">GLE_5429</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PspA/IM30 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949802.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5429"/>
    <dbReference type="EnsemblBacteria" id="ALN60770">
        <property type="protein sequence ID" value="ALN60770"/>
        <property type="gene ID" value="GLE_5429"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5429"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5345"/>
    <dbReference type="OrthoDB" id="1886134at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007157">
        <property type="entry name" value="PspA_IM30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31088">
        <property type="entry name" value="PTHR31088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04012">
        <property type="entry name" value="PspA_IM30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="229"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="89"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW24354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="254" mass="28024" checksum="3F7EF4A2B05B335A" modified="2016-02-17" version="1">MSILQKILTLFRGTAHEAGQAVVDANALKILDQEIRDAGTELSRSKEELTKVMAQRQLQANRSKDRFAKKAEYETYIAGALRQGNEQLAREVAERLAAVENDLKNDEQAITSYDNSISQLKTAIAATERKLARVKQQVDTVKATEAVQRAQTAVASRHSGANGKVTTALDSLERIQQRQAERGARLEAAAQLESEAGEGDLNKRLQAAGLLPESTSVDNILERFREKPVQQLSHEPLSLPAAEIKETDKVERKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQD7</accession>
    <name>A0A0S2DQD7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Aminodeoxychorismate synthase</fullName>
            <ecNumber evidence="2">2.6.1.85</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pabB</name>
        <name evidence="7" type="ORF">GLE_5441</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the anthranilate synthase component I family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.85" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949811.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5441"/>
    <dbReference type="EnsemblBacteria" id="ALN60782">
        <property type="protein sequence ID" value="ALN60782"/>
        <property type="gene ID" value="GLE_5441"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5441"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5357"/>
    <dbReference type="OMA" id="DWSVNIR"/>
    <dbReference type="OrthoDB" id="1786019at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046820">
        <property type="term" value="F:4-amino-4-deoxychorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009396">
        <property type="term" value="P:folic acid-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005802">
        <property type="entry name" value="ADC_synth_comp_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="PTHR11236"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00553">
        <property type="entry name" value="pabB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00566">
        <property type="entry name" value="trpG_papA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="4">
        <location>
            <begin position="4"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Anth_synt_I_N" evidence="6">
        <location>
            <begin position="259"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate_bind" evidence="5">
        <location>
            <begin position="435"/>
            <end position="689"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN60782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="721" mass="77516" checksum="DB8A23117F3468F4" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQH6</accession>
    <name>A0A0S2DQH6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5482</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60823">
        <property type="protein sequence ID" value="ALN60823"/>
        <property type="gene ID" value="GLE_5482"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5482"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5396"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="52" mass="6003" checksum="6F836EA72CB75C91" modified="2016-02-17" version="1">MRDINSYDVGISQNSKHFVFIFLVRNKNFSGGGGEIWVSKESLKVERTSNYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-01-23" modified="2021-06-02" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A1EBU7</accession>
    <name>A1EBU7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein orf5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">orf5</name>
        <name evidence="4" type="ORF">BV903_11070</name>
        <name evidence="5" type="ORF">FE772_24730</name>
        <name evidence="3" type="ORF">GLE_5103</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2006-11" db="EMBL/GenBank/DDBJ databases">
            <title>A type III secretion system from the microbial antagonist and biological control bacterium, Lysobacter enzymogenes strain C3.</title>
            <authorList>
                <person name="Reedy R.M."/>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="EF119743">
        <property type="protein sequence ID" value="ABL60000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000026">
        <property type="protein sequence ID" value="OPD63844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949556.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60444">
        <property type="protein sequence ID" value="ALN60444"/>
        <property type="gene ID" value="GLE_5103"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63844">
        <property type="protein sequence ID" value="OPD63844"/>
        <property type="gene ID" value="BV903_11070"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5103"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5028"/>
    <dbReference type="OrthoDB" id="1899890at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABL60000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD63844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW28378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="262" mass="28452" checksum="3B4777DBC235A25E" modified="2007-01-23" version="1">MSTIRNSSANEDAKRAQQLAQEAQLSDRQRAARQSAPAESVDQFRELMQQRQAVGQKGEQTLGAQPEDGQYAAGDAAAQALRGRQQNALERGRNQYAQDQTAQNQAAQGQARQHGVEQKSRDEQRYSVGFDRGGGDGQSSEQSGLWLAQQAMRADQTAPMQAPAPTSNAAAFAELVERHVRQLAVGGGGADGGDGQVLLRLSDQTLPGTDLLLSKTADGWQLRADSRSRSSYDAIREAGPELMRRFAERNLGRLSIDPHFHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA43</accession>
    <name>A0A0S2DA43_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Biotin synthase</fullName>
            <ecNumber evidence="3 13">2.8.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13 16" type="primary">bioB</name>
        <name evidence="16" type="ORF">GLE_0061</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>(4R,5S)-dethiobiotin + [sulfur carrier]-SH + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + [sulfur carrier]-H + biotin + 2 L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:22060"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:149473"/>
            <dbReference type="EC" id="2.8.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="13 14">Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="13 14">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 13">Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the radical SAM superfamily. Biotin synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.6" evidence="3 13"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0061"/>
    <dbReference type="EnsemblBacteria" id="ALN55420">
        <property type="protein sequence ID" value="ALN55420"/>
        <property type="gene ID" value="GLE_0061"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0061"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.67"/>
    <dbReference type="OMA" id="ADRFCMG"/>
    <dbReference type="UniPathway" id="UPA00078">
        <property type="reaction ID" value="UER00162"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004076">
        <property type="term" value="F:biotin synthase activity"/>
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        <location>
            <begin position="46"/>
            <end position="270"/>
        </location>
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            <position position="61"/>
        </location>
        <ligand>
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        <location>
            <position position="105"/>
        </location>
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        </ligand>
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        </location>
        <ligand>
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        </ligand>
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        </ligand>
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        </source>
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        <source>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
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        <source>
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        </source>
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            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="347" mass="37865" checksum="BF3CCD448AD362A6" modified="2016-02-17" version="1">MPNMSPESTPLRHDWSRAEVRALFDLSFPELLHRAASVHKAHFDPAEVQVSTLLSVKTGGCPEDCAYCPQAQRYHTGVDATKLMSTEAVLEKAKQAKAAGASRFCMGAAWRSPKDRDIPKVAAMIREVKSLGLETCATLGMLSGEQAQKLKAAGLDYYNHNLDTAPEFYNEIIRTREFQDRLDTLEHVRDAGMKTCCGGIVGMGESREQRAGLLQTLANLPAHPDSVPINRLVQVEGTPLAGTTELDPFEFVRTIAVARLMMPKSMVRLSAGRESMSDELQALCFLAGANSIFYGEKLLTTGNPDTERDLALFARLGLRPMQVVETAGTVHASIEDHEALPAHTCAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA52</accession>
    <name>A0A0S2DA52_LYSEN</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0022</name>
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        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
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            <taxon>Bacteria</taxon>
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        </lineage>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="42" mass="4483" checksum="3C4ED4F85753D0AC" modified="2016-02-17" version="1">MRIGDECGGGAVARRRASQRCEWCNNPLLFIGSPRMTTSGGA</sequence>
</entry>
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    <accession>A0A0S2DA57</accession>
    <name>A0A0S2DA57_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0056</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55415">
        <property type="protein sequence ID" value="ALN55415"/>
        <property type="gene ID" value="GLE_0056"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="47" mass="5016" checksum="D4696E0F71529E7E" modified="2016-02-17" version="1">MPPLRTSAAAPSLPGIAITLCGARACVNARRGRNRSRRAPDPILFDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAM2</accession>
    <name>A0A0S2DAM2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GntR family transcriptional regulator</fullName>
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        <submittedName>
            <fullName evidence="6">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FE772_01935</name>
        <name evidence="6" type="ORF">GLE_0218</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW24620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0218"/>
    <dbReference type="EnsemblBacteria" id="ALN55577">
        <property type="protein sequence ID" value="ALN55577"/>
        <property type="gene ID" value="GLE_0218"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0218"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.220"/>
    <dbReference type="OMA" id="FHRAINI"/>
    <dbReference type="OrthoDB" id="1911275at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="5">
        <location>
            <begin position="6"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="213"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN55577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW24620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="236" mass="26365" checksum="6B464BB35DDE38F2" modified="2016-02-17" version="1">MSILPRSLSDQAFEVVRERILSTQIPPLAPIRQELLAEELGISKIPLREALSRLEEQGLLSSHPNRGFFVPPLSSTEAEEVFALRLKIEPEAAAQACLVACDAGQEAARAAFEAWERSDHADPNASVRCNRAFHLALVTPGGRQITAQLVERLQVLAERYVRKHLEPAGREARAANEHLGILQSWLQRDAARVDQLLSTHILSTLHDLRAQLEQIPQTGPTLPDFRRAPRRRREPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAM3</accession>
    <name>A0A0S2DAM3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Inner membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_0241</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0324 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0241"/>
    <dbReference type="EnsemblBacteria" id="ALN55600">
        <property type="protein sequence ID" value="ALN55600"/>
        <property type="gene ID" value="GLE_0241"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0241"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.243"/>
    <dbReference type="OMA" id="FGLWCAI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004630">
        <property type="entry name" value="UPF0324_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018383">
        <property type="entry name" value="UPF0324_pro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30106">
        <property type="entry name" value="PTHR30106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03601">
        <property type="entry name" value="Cons_hypoth698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00698">
        <property type="entry name" value="TIGR00698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="268"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="325"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN55600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="354" mass="35738" checksum="258E2D8D2F57FA54" modified="2016-02-17" version="1">MSAALTPTSPVPAAPQGAHRQPGFWPGLALAAAIAAAAMGLAALPALQAAGLSALTLAIVLGIAAGNTVFPAIAGRVGSGVDFSKAMLLRAGIVLYGLRVTFQEIAGVGAAGLAVDIVVVAGIFCLGTWLGTRWLKLDRETSMLIGAGSAICGAAAVMATEPVVKGQAHKVSVAVATVVVFGTVGMFVYPWAYPYLGLSEHAYGVFAGSTIHEVAQVVVAGRAVSEQAASAAVIEKMLRVMLLAPFLLILSSRLGAGGGADGTRSKIVIPWFALLFVAVSGINSLHLLPAAWKAALIQLDTVLLAMAMAALGLRTHIGAIRQAGAKPMLLAAVLFATLTVGGYALNVGAAKLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAT6</accession>
    <name>A0A0S2DAT6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0073</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55432">
        <property type="protein sequence ID" value="ALN55432"/>
        <property type="gene ID" value="GLE_0073"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0073"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="98" mass="10178" checksum="569F995462FF2B07" modified="2016-02-17" version="1">MPGLHRISGTKGVPWIASSLPQRVVSARPASVGTLPRGARHGVGFRRSAVSWSSLPVGSATRVALATSLSLVALARRPSTAGADFRPHRSVGNRACPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAW5</accession>
    <name>A0A0S2DAW5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0322</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55680">
        <property type="protein sequence ID" value="ALN55680"/>
        <property type="gene ID" value="GLE_0322"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0322"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.319"/>
    <dbReference type="OMA" id="MIVIFRT"/>
    <dbReference type="OrthoDB" id="1912724at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="177" mass="18834" checksum="BAA20E858DEA478B" modified="2016-02-17" version="1">MVALLLLSAAAHAGGAPFSCELGTARDKRPVVVNAQDVESGAATYFLRYGGKPAQPAIRDIEHSRGLDARLSCLGGKRRAMLLFGEFGAGYPHGVVLSYNPATAAFERIDFAERALPSRIYLGERGSLVVIPTGGRGETDARYVVYRYAAGKGQDEESEATDELPAAAGYTVITLNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB08</accession>
    <name>A0A0S2DB08_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, lacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_0377</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945990.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0377"/>
    <dbReference type="EnsemblBacteria" id="ALN55735">
        <property type="protein sequence ID" value="ALN55735"/>
        <property type="gene ID" value="GLE_0377"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0377"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.374"/>
    <dbReference type="OMA" id="RANEWET"/>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="11"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN55735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="350" mass="37583" checksum="FFE1049E05305647" modified="2016-02-17" version="1">MNDAPAPRGRVTLADIARACGLSRATVSLVLRGSPLVHADTRARVEAELKRQGYVYHRGAANLRRKVSTGVALVINDLSNPFFAEFAAGVDEWLATAGFVTLLGSTNESVERQQAVLNSLMEHDPAGIILSPAEGSDGARVRAQVGERTPVLVFNRELDSTAWDFLALDNTHGARLATRHLLDRGHRRIAFFGGHRDSSSCRQRRQGYREALAEAGIEPEPQWLIECAPTRLEAAQQTGALFVRDPAPTAAVCYNDAVALGLMAGLVARGRRAGGDFAVVGFDDIPEAAVASPPLTTIAVDPRARGRQAAELILKRLREPELAPAHTIAPVRLQARSSSEVHLTPPGEPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB30</accession>
    <name>A0A0S2DB30_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterial membrane flanked domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0364</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0364"/>
    <dbReference type="EnsemblBacteria" id="ALN55722">
        <property type="protein sequence ID" value="ALN55722"/>
        <property type="gene ID" value="GLE_0364"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0364"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.361"/>
    <dbReference type="OMA" id="EVMLHPF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005182">
        <property type="entry name" value="DUF304"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014529">
        <property type="entry name" value="UCP026631"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03703">
        <property type="entry name" value="bPH_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026631">
        <property type="entry name" value="UCP026631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="399"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="2">
        <location>
            <begin position="95"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="2">
        <location>
            <begin position="287"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="2">
        <location>
            <begin position="434"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="525" mass="58176" checksum="277627FB0AE566FF" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB52</accession>
    <name>A0A0S2DB52_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">50S ribosomal protein L28</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmB</name>
        <name evidence="5" type="ORF">GLE_0169</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL28 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0169"/>
    <dbReference type="EnsemblBacteria" id="ALN55528">
        <property type="protein sequence ID" value="ALN55528"/>
        <property type="gene ID" value="GLE_0169"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0169"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.171"/>
    <dbReference type="OMA" id="HTRRRWE"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="L28p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026569">
        <property type="entry name" value="Ribo_L28/L24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037147">
        <property type="entry name" value="Ribo_L28/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001383">
        <property type="entry name" value="Ribosomal_L28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528">
        <property type="entry name" value="PTHR13528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00830">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="SSF143800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00009">
        <property type="entry name" value="L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN55528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="57" mass="6797" checksum="3EFAA9004AEE3FCB" modified="2016-02-17" version="1">MNKTRRRFLPNLHERRFWVASENRWVKLRVSAHALRTIDKNGIDAVLAELRARGEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB53</accession>
    <name>A0A0S2DB53_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AGE family epimerase/isomerase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">N-acylglucosamine 2-epimerase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_02660</name>
        <name evidence="3" type="ORF">GLE_0374</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the N-acylglucosamine 2-epimerase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945987.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0374"/>
    <dbReference type="EnsemblBacteria" id="ALN55732">
        <property type="protein sequence ID" value="ALN55732"/>
        <property type="gene ID" value="GLE_0374"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0374"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.371"/>
    <dbReference type="OMA" id="WVQAETF"/>
    <dbReference type="OrthoDB" id="783590at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00249">
        <property type="entry name" value="AGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034116">
        <property type="entry name" value="AGE_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="404" mass="46942" checksum="2EBB9643BE9513DB" modified="2016-02-17" version="1">MNLPLDPLPNFRDADTLLAHIRDTLAFYDPVALDADGGFFHYFRDDGSVYDASHRHLVSSTRFVFNYAMAAVEFGRDDYRERARHGLRYLRDVHRNPDTGGYAWTIRDGRPEDRMNHCYGVAFVLLAYSCGVKAGIGEAAAWMDETWNLLEARFWEPEFGLYRDEADADWNFTGYRGQNANMHMCEAMLAAYEASNDARYLERALTLAQNMTQRQAAQADGLVWEHYDRDWNIDWDYHRDDPKHLFRPWGFQPGHQTEWAKLLLILDRHLSARGDASAWLVPTARHLFDTAIARSWDDEFGGLAYGFAPDGAVCDDDKYFWVQAESLATAALLAVRTGENLYWQWYDKLWAYAWQHMVDHRYGAWYRILDRRNGKYSDEKSPAGKTDYHTMGACYEVIRWLRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBM1</accession>
    <name>A0A0S2DBM1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0573</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55931">
        <property type="protein sequence ID" value="ALN55931"/>
        <property type="gene ID" value="GLE_0573"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0573"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.566"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="37" mass="4221" checksum="79473B1A0DA6E657" modified="2016-02-17" version="1">MVAGRRLRSRRRRRAAGIAPRPTRAALRRGECAFATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBX6</accession>
    <name>A0A0S2DBX6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56030">
        <property type="protein sequence ID" value="ALN56030"/>
        <property type="gene ID" value="GLE_0672"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0672"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.661"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="96" mass="10830" checksum="87C618B25FF6878A" modified="2016-02-17" version="1">MSDAHGRNMNDVRACFGARRARTRKRVDAMARMRARRLNGTETKRFVFAGSSPRMRSRGAENRCMRNPPRARSAPPAARPHPAPCASRHDRHGQPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBY8</accession>
    <name>A0A0S2DBY8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">LysE family translocator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Translocator protein, LysE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FE772_03920</name>
        <name evidence="6" type="ORF">GLE_0643</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946184.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56001">
        <property type="protein sequence ID" value="ALN56001"/>
        <property type="gene ID" value="GLE_0643"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0643"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.632"/>
    <dbReference type="OMA" id="FARMGHW"/>
    <dbReference type="OrthoDB" id="1927576at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006324">
        <property type="entry name" value="LeuE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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            <end position="95"/>
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    <feature type="transmembrane region" description="Helical" evidence="5">
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            <begin position="116"/>
            <end position="137"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="149"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN56001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW24944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="207" mass="21671" checksum="98EF3D3F09C5D218" modified="2016-02-17" version="1">MDPQTLAAFFATALFLAVVPGPDNVFVLTQSALRGKRAGLWVVLGLCSGLLVHTAAVALGVAALFERSPLAFDLLKYAGAAYLLYLAWQSLRAPAMAIDAGAGARGNAGRLYLRGIVMNVSNPKVSIFFLAFLPQFVDKQAGSVTLQMLALGATFILATALVFGALALSAGAVGQRFARSQRAQRWMNRAAAAVFAGLAAKLATAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC60</accession>
    <name>A0A0S2DC60_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56108">
        <property type="protein sequence ID" value="ALN56108"/>
        <property type="gene ID" value="GLE_0750"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0750"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.738"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="51" mass="5464" checksum="025796AA19CF0533" modified="2016-02-17" version="1">MRGGRRRVLRPARQSRAAAVSPGAPAGPLWRYPRGDGAAGCPPARIRARSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCG6</accession>
    <name>A0A0S2DCG6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">K(+)-insensitive pyrophosphate-energized proton pump</fullName>
            <ecNumber evidence="9">7.1.3.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Membrane-bound proton-translocating pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Pyrophosphate-energized inorganic pyrophosphatase</fullName>
            <shortName evidence="9">H(+)-PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hppA</name>
        <name evidence="14" type="ORF">FE772_04915</name>
        <name evidence="13" type="ORF">GLE_0850</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">C3</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>diphosphate + H(+)(in) + H2O = 2 H(+)(out) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:13973"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="7.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="7.1.3.1" evidence="9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946343.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0850"/>
    <dbReference type="EnsemblBacteria" id="ALN56208">
        <property type="protein sequence ID" value="ALN56208"/>
        <property type="gene ID" value="GLE_0850"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0850"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.838"/>
    <dbReference type="OMA" id="MATTAMQ"/>
    <dbReference type="OrthoDB" id="98036at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009678">
        <property type="term" value="F:pyrophosphate hydrolysis-driven proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01129">
        <property type="entry name" value="PPase_energized_pump"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004131">
        <property type="entry name" value="PPase-energised_H-pump"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31998">
        <property type="entry name" value="PTHR31998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03030">
        <property type="entry name" value="H_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01104">
        <property type="entry name" value="V_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="122"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="235"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="322"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="367"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="399"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="462"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="499"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="568"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="593"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="12">
        <location>
            <begin position="729"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="695"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="816"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="site" description="Determinant of potassium independence" evidence="9">
        <location>
            <position position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN56208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW25112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="837" mass="84953" checksum="5BC0261D4EEB9516" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCH6</accession>
    <name>A0A0S2DCH6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">SNARE associated Golgi protein/PAP2 superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_0864</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DedA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <source>
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        <source>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="669" mass="73388" checksum="9611898DC62CE394" modified="2016-02-17" version="1"> </sequence>
</entry>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">C3</strain>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="ALN56533.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
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</entry>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
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    </dbReference>
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    </dbReference>
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        </location>
    </feature>
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        </source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW28660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="304" mass="33818" checksum="DE41C29E17514563" modified="2016-02-17" version="1">MDRIADLNLFLRVLDLGSISAAARSLDLSAAVASQRLKRLERDLGVRLLHRTTRQLHATAEGLALAERGRALIEELEGLTDDLRRAGSEPAGQLRVTTSAAFGRLYLSPLLPEFQRRYPLVRLSVNLSDENLDLIAAGMDLAIRIGRLDDSNLVARKLANNRRVLACSPEYLRRHGAPRAPQDLAAHECLLLVGAQGRMENWRVLDAAGRESVVRVNGRLESNFGEVLRDAAIAGLGIAHFSVWHVHEDLRAGRLVQVLPKHRLPDTAIHAVMPQRRYVPLRVRAFIDFMAESFGEVPPWERGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDN2</accession>
    <name>A0A0S2DDN2_LYSEN</name>
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        <submittedName>
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        </submittedName>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_06855</name>
        <name evidence="2" type="ORF">GLE_1271</name>
    </gene>
    <organism evidence="2 4">
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        <lineage>
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            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1271"/>
    <dbReference type="EnsemblBacteria" id="ALN56628">
        <property type="protein sequence ID" value="ALN56628"/>
        <property type="gene ID" value="GLE_1271"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1271"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1254"/>
    <dbReference type="OMA" id="RYRMVYL"/>
    <dbReference type="OrthoDB" id="1268974at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003313">
        <property type="entry name" value="AraC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037923">
        <property type="entry name" value="HTH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02311">
        <property type="entry name" value="AraC_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51215">
        <property type="entry name" value="SSF51215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="174"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="274" mass="31425" checksum="0B146A4A8D3195EA" modified="2016-02-17" version="1">MQGVPDRFDATSDAAQFRQVAHRPGVELYRAHIVRHSFDPHTHEAYGLGAIESGVERFRYRGSDHLAPPDSLVLMNPDVLHTGHAVTAEGWRYRMIYVEPQAAAQITGDEGWWFDDAVRHDPARARRVTARLDALWHAREPLAFDSQLHALLDEFRDHARMPRRARPEAPKRFVPVLDYLRAQLAERVTLEELAAVADLSPFHFLRQFRAQYHVTPQQMLMALRLYEAKRLLAAGLPPARIAAETGLTDQAHFTRAFQRRYGITPARYQKQIRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDU2</accession>
    <name>A0A0S2DDU2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Urocanate hydratase</fullName>
            <shortName evidence="9">Urocanase</shortName>
            <ecNumber evidence="4 9">4.2.1.49</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Imidazolonepropionate hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 13" type="primary">hutU</name>
        <name evidence="14" type="ORF">FE772_07255</name>
        <name evidence="13" type="ORF">GLE_1368</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">C3</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>4-imidazolone-5-propanoate = H2O + trans-urocanate</text>
            <dbReference type="Rhea" id="RHEA:13101"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17771"/>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
            <dbReference type="EC" id="4.2.1.49"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="9">Binds 1 NAD(+) per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Amino-acid degradation; L-histidine degradation into L-glutamate; N-formimidoyl-L-glutamate from L-histidine: step 2/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the urocanase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.49" evidence="4 9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946720.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1368"/>
    <dbReference type="EnsemblBacteria" id="ALN56725">
        <property type="protein sequence ID" value="ALN56725"/>
        <property type="gene ID" value="GLE_1368"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1368"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1350"/>
    <dbReference type="OMA" id="LVGDWAN"/>
    <dbReference type="OrthoDB" id="100619at2"/>
    <dbReference type="UniPathway" id="UPA00379">
        <property type="reaction ID" value="UER00550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016153">
        <property type="term" value="F:urocanate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019556">
        <property type="term" value="P:histidine catabolic process to glutamate and formamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019557">
        <property type="term" value="P:histidine catabolic process to glutamate and formate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00577">
        <property type="entry name" value="HutU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023637">
        <property type="entry name" value="Urocanase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035401">
        <property type="entry name" value="Urocanase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038364">
        <property type="entry name" value="Urocanase_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023636">
        <property type="entry name" value="Urocanase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035400">
        <property type="entry name" value="Urocanase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035085">
        <property type="entry name" value="Urocanase_Rossmann-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036190">
        <property type="entry name" value="Urocanase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12216">
        <property type="entry name" value="PTHR12216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01175">
        <property type="entry name" value="Urocanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17392">
        <property type="entry name" value="Urocanase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17391">
        <property type="entry name" value="Urocanase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001423">
        <property type="entry name" value="Urocanate_hydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111326">
        <property type="entry name" value="SSF111326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01228">
        <property type="entry name" value="hutU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01233">
        <property type="entry name" value="UROCANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0369">Histidine metabolism</keyword>
    <keyword evidence="7 9 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 9" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Urocanase_N" evidence="11">
        <location>
            <begin position="13"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Urocanase" evidence="10">
        <location>
            <begin position="142"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="Urocanase_C" evidence="12">
        <location>
            <begin position="353"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="412"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="54"/>
            <end position="55"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="178"/>
            <end position="180"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="244"/>
            <end position="245"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="265"/>
            <end position="269"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="275"/>
            <end position="276"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="494"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN56725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW25492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="556" mass="60797" checksum="3FC00473885B1C10" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDZ5</accession>
    <name>A0A0S2DDZ5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FdhF/YdeP family oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Oxidoreductase alpha (Molybdopterin) subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_07500</name>
        <name evidence="7" type="ORF">GLE_1420</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946763.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1420"/>
    <dbReference type="EnsemblBacteria" id="ALN56777">
        <property type="protein sequence ID" value="ALN56777"/>
        <property type="gene ID" value="GLE_1420"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1420"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1399"/>
    <dbReference type="OMA" id="DCSDLCH"/>
    <dbReference type="OrthoDB" id="50471at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008863">
        <property type="term" value="F:formate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02787">
        <property type="entry name" value="MopB_CT_ydeP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02767">
        <property type="entry name" value="MopB_ydeP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037951">
        <property type="entry name" value="MopB_CT_YdeP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010046">
        <property type="entry name" value="Mopterin_OxRdtse_a_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041953">
        <property type="entry name" value="YdeP_MopB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43105:SF4">
        <property type="entry name" value="PTHR43105:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01701">
        <property type="entry name" value="Fdhalpha-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Molybdopterin" evidence="5">
        <location>
            <begin position="110"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="Molydop_binding" evidence="6">
        <location>
            <begin position="650"/>
            <end position="757"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN56777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW25531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="784" mass="86252" checksum="A1F314A52DAFB4B5" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE57</accession>
    <name>A0A0S2DE57_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_13090</name>
        <name evidence="4" type="ORF">FE772_07535</name>
        <name evidence="2" type="ORF">GLE_1428</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000033">
        <property type="protein sequence ID" value="OPD63469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946768.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1428"/>
    <dbReference type="EnsemblBacteria" id="ALN56785">
        <property type="protein sequence ID" value="ALN56785"/>
        <property type="gene ID" value="GLE_1428"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63469">
        <property type="protein sequence ID" value="OPD63469"/>
        <property type="gene ID" value="BV903_13090"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1428"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1409"/>
    <dbReference type="OMA" id="LMPHMDD"/>
    <dbReference type="OrthoDB" id="2052675at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="98" mass="10570" checksum="0BE0A20062BDA22C" modified="2016-02-17" version="1">MPLLRLRITGNDDDARAIGNLLNSLDGIERVEEVADLMPHMDDADSSSAGLPDDTGPGVHELEIDAPNAATANKVREAVEALAFDLDVLVEFEAEEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEK6</accession>
    <name>A0A0S2DEK6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ErfK/YbiS/YcfS/YnhG family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_1723</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YkuD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1723"/>
    <dbReference type="EnsemblBacteria" id="ALN57078">
        <property type="protein sequence ID" value="ALN57078"/>
        <property type="gene ID" value="GLE_1723"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1723"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1701"/>
    <dbReference type="OMA" id="MIHGLPN"/>
    <dbReference type="OrthoDB" id="1654458at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071972">
        <property type="term" value="F:peptidoglycan L,D-transpeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16913">
        <property type="entry name" value="YkuD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005490">
        <property type="entry name" value="LD_TPept_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038063">
        <property type="entry name" value="Transpep_catalytic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03734">
        <property type="entry name" value="YkuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141523">
        <property type="entry name" value="SSF141523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594753" evidence="5">
        <location>
            <begin position="31"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="YkuD" evidence="6">
        <location>
            <begin position="49"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="179" mass="19270" checksum="6A1936503B2AAD26" modified="2016-02-17" version="1">MSASLRSNRAIGAIPAMAAAALLAVSLAWAAPASARTPPAMAAKAEQADFIVVDKSARRMQLLRGGKVLKSYAILLGDAPTGHKRQQGDERTPEGEYRISGRNQNSRFHLSLRVSYPNAADRKQAQARGVDPGGDIMIHGGTPPGYRRDWTDGCVAVTDREIEDIWSRVPTGTPIRIDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEM0</accession>
    <name>A0A0S2DEM0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Hydroxyacylglutathione hydrolase</fullName>
            <ecNumber evidence="5">3.1.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Glyoxalase II</fullName>
            <shortName evidence="5">Glx II</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">gloB</name>
        <name evidence="8" type="ORF">FE772_08590</name>
        <name evidence="7" type="ORF">GLE_1658</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>an S-(2-hydroxyacyl)glutathione + H2O = a 2-hydroxy carboxylate + glutathione + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21864"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58896"/>
            <dbReference type="ChEBI" id="CHEBI:71261"/>
            <dbReference type="EC" id="3.1.2.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.6" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946953.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1658"/>
    <dbReference type="EnsemblBacteria" id="ALN57015">
        <property type="protein sequence ID" value="ALN57015"/>
        <property type="gene ID" value="GLE_1658"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1658"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1637"/>
    <dbReference type="OMA" id="NYIWLLQ"/>
    <dbReference type="OrthoDB" id="733552at2"/>
    <dbReference type="UniPathway" id="UPA00619">
        <property type="reaction ID" value="UER00676"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004416">
        <property type="term" value="F:hydroxyacylglutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019243">
        <property type="term" value="P:methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07723">
        <property type="entry name" value="hydroxyacylglutathione_hydrolase_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01374">
        <property type="entry name" value="Glyoxalase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035680">
        <property type="entry name" value="Clx_II_MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032282">
        <property type="entry name" value="HAGH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017782">
        <property type="entry name" value="Hydroxyacylglutathione_Hdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16123">
        <property type="entry name" value="HAGH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005457">
        <property type="entry name" value="Glx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03413">
        <property type="entry name" value="GSH_gloB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lactamase_B" evidence="6">
        <location>
            <begin position="11"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW25718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="260" mass="27782" checksum="04A5EB0209616487" modified="2016-02-17" version="1">MRLTALPALSDNYIWVLAGDDGRALIVDPGEPGPVLAAAADGLVPEAILLTHHHNDHIGGTAALLERWPQIPVYSPQDERIAEATQRLGEGARFDAAGHAVRILEVPGHTRSHIAYVIDDGPDGAPLAFTGDTLFSLGCGRLFEGTPAQMLASLDRLAALPDPTRVCCGHEYTLSNAAFARVVDPDNPALRRRIEQAQAMRNAGLATLPVTLAEERATNPFLRSRAPALVAAVAARLGRAPADEVETFAELRSWKDGFRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEP9</accession>
    <name>A0A0S2DEP9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">3-oxoacyl-[acyl-carrier-protein] synthase 3</fullName>
            <ecNumber evidence="8">2.3.1.180</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">3-oxoacyl-[acyl-carrier-protein] synthase III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Beta-ketoacyl-ACP synthase III</fullName>
            <shortName evidence="8">KAS III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">fabH</name>
        <name evidence="12" type="ORF">FE772_08755</name>
        <name evidence="11" type="ORF">GLE_1689</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>acetyl-CoA + H(+) + malonyl-[ACP] = 3-oxobutanoyl-[ACP] + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:12080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9625"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78450"/>
            <dbReference type="EC" id="2.3.1.180"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the thiolase-like superfamily. FabH family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.180" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946980.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1689"/>
    <dbReference type="EnsemblBacteria" id="ALN57045">
        <property type="protein sequence ID" value="ALN57045"/>
        <property type="gene ID" value="GLE_1689"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1689"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1667"/>
    <dbReference type="OMA" id="WGSEGDK"/>
    <dbReference type="OrthoDB" id="872193at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033818">
        <property type="term" value="F:beta-ketoacyl-acyl-carrier-protein synthase III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01815">
        <property type="entry name" value="FabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013751">
        <property type="entry name" value="ACP_syn_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004655">
        <property type="entry name" value="FabH_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08545">
        <property type="entry name" value="ACP_syn_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00747">
        <property type="entry name" value="fabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACP_syn_III" evidence="10">
        <location>
            <begin position="110"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="ACP_syn_III_C" evidence="9">
        <location>
            <begin position="237"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="ACP-binding" evidence="8">
        <location>
            <begin position="254"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN57045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW25743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="326" mass="35075" checksum="C878866EE38D48FA" modified="2016-02-17" version="1">MTDRIYARIAGTGSYLPAQVVTNDELAKRVETSDEWIRTRTGIRQRHVAAEGETTVDLAYQASLRALEAAGTTPEEIDLIILGTTTPDLIFPSSACLLQHRLGANGCPAFDVNAACSGFVYALTVADKFIRSGAAKTVLVVGAETLTRMLDWTDRSTCVLFGDGAGAVVLKADSETGILSTHLHADGGKKELLWNPVGVSAGFKPEEHNAGVRVLMTGNEVFKHAVKALDSVVEETLEANGLDRHEIDWLIPHQANLRIIEATAKRLDMPMERVIVTVDKHGNTSSGSVPLALDEAVRSGKVQRGQLLLLEAFGGGFTWGSALLRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEW0</accession>
    <name>A0A0S2DEW0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BV903_13295</name>
        <name evidence="8" type="ORF">FE772_08860</name>
        <name evidence="6" type="ORF">GLE_1713</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">C3</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000034">
        <property type="protein sequence ID" value="OPD63403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946997.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1713"/>
    <dbReference type="EnsemblBacteria" id="ALN57068">
        <property type="protein sequence ID" value="ALN57068"/>
        <property type="gene ID" value="GLE_1713"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63403">
        <property type="protein sequence ID" value="OPD63403"/>
        <property type="gene ID" value="BV903_13295"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1713"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1691"/>
    <dbReference type="OMA" id="ERRHDLW"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="8"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="HPt" evidence="5">
        <location>
            <begin position="156"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="2">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD63403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW25759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="241" mass="25310" checksum="B981D5313F8CE149" modified="2016-02-17" version="1">MKNSQVPRVLLVEDDPTSRAFLTAAVEAVPAQVDGADSLAAAMALGASTDYQLWLFDAHLPDGSGSELLERLRRSHPATPALAHTATGESEVRDRLIASGFCEVLVKPLPAAAVRGAIRRLLGLPESDAPAAACAADADTAPVWDDESAARALNGNRAHILTLRGLFVQELPNARRSILAAAQLGNLDALRGELHKLRASCGFVGAARLGQTVQALQAQLDSAEGLARFDQVARETIELAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEY9</accession>
    <name>A0A0S2DEY9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_1563</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946879.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1563"/>
    <dbReference type="EnsemblBacteria" id="ALN56920">
        <property type="protein sequence ID" value="ALN56920"/>
        <property type="gene ID" value="GLE_1563"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1563"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1543"/>
    <dbReference type="OMA" id="ANAFWLG"/>
    <dbReference type="OrthoDB" id="72068at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="14"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="1">
        <location>
            <begin position="14"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="525"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1107" mass="121999" checksum="DF287A5EEAF84ABB" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF86</accession>
    <name>A0A0S2DF86_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1833</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57185">
        <property type="protein sequence ID" value="ALN57185"/>
        <property type="gene ID" value="GLE_1833"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1833"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1804"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="75" mass="7508" checksum="A1EAF36E4B3AB407" modified="2016-02-17" version="1">MQAHGRKAWVRVHSSGRARCAGRRGEHFPAAARTCAGRAAPRAAAGICAVPARSGAARAPGERDAAPPGAPRGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFE2</accession>
    <name>A0A0S2DFE2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Probable alginate O-acetylase</fullName>
            <ecNumber evidence="11">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FE772_09240</name>
        <name evidence="13" type="ORF">GLE_1799</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">C3</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">YC36</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2 11">Glycan biosynthesis; alginate biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the membrane-bound acyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="11"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947057.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1799"/>
    <dbReference type="EnsemblBacteria" id="ALN57152">
        <property type="protein sequence ID" value="ALN57152"/>
        <property type="gene ID" value="GLE_1799"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1799"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1771"/>
    <dbReference type="OMA" id="IIWGAWH"/>
    <dbReference type="OrthoDB" id="1297594at2"/>
    <dbReference type="UniPathway" id="UPA00286"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042121">
        <property type="term" value="P:alginic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024194">
        <property type="entry name" value="Ac/AlaTfrase_AlgI/DltB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028362">
        <property type="entry name" value="AlgI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500217">
        <property type="entry name" value="AlgI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016636">
        <property type="entry name" value="AlgI_DltB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7 11" id="KW-0016">Alginate biosynthesis</keyword>
    <keyword evidence="11" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="30"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="315"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="359"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="414"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="444"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR016636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN57152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW25820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="474" mass="53860" checksum="18BEF479EE915621" modified="2016-02-17" version="1">MVFSSPAFLFVFFPLFFGLYFLLPRALRNAWILLSSVLFYALGAGPFTLLPLGLVAANWALSHLIERLRDRRIGALPADRLALWLGVAMNLIPLLLFKYLVFFAQIAADFLGPMAAFDPAKLGWILPLGISFYSFHFISYLVDVYQRHIPAERSVAKFAIYIFLFPHLVAGPIVRFAEIKSQLGIERRGLVGRDVYWGLLIFIVGLAKKILIADPLGSVVDVVHSGDLHLSTYSAWLAALCYSFQIYFDFSGYTDMAIGMARMMGFRFPQNFDRPYTSHSVTEFWRRWHMTLSRWFRDYLYIPLGGNRGSAQRTYFNLLVIFVLCGLWHGAAYTFLVWGLGHGLLLVLERAKLLRLQNLPAANLWVFALVTLLWVPFRSKDLATTGKLLKAMFGLEPSVPLWVEANRMLANPKILFLLALAALICLIGRPTFDKLRSFSFKTPALMPVYCAVLYFLACISVVESGFNPFIYFQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFI1</accession>
    <name>A0A0S2DFI1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Alpha-lytic protease prodomain/trypsin</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="11">S1 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FE772_08930</name>
        <name evidence="10" type="ORF">GLE_1730</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947011.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1730"/>
    <dbReference type="EnsemblBacteria" id="ALN57085">
        <property type="protein sequence ID" value="ALN57085"/>
        <property type="gene ID" value="GLE_1730"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1730"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1708"/>
    <dbReference type="OMA" id="YTGNVRC"/>
    <dbReference type="OrthoDB" id="1110723at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.50">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037295">
        <property type="entry name" value="Alpha-lytic_protease_prodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004236">
        <property type="entry name" value="Pept_S1_alpha_lytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001316">
        <property type="entry name" value="Pept_S1A_streptogrisin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035070">
        <property type="entry name" value="Streptogrisin_prodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02983">
        <property type="entry name" value="Pro_Al_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001134">
        <property type="entry name" value="Streptogrisin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00861">
        <property type="entry name" value="ALYTICPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54806">
        <property type="entry name" value="SSF54806"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 10" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242135" evidence="7">
        <location>
            <begin position="34"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Pro_Al_protease" evidence="9">
        <location>
            <begin position="119"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="8">
        <location>
            <begin position="229"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="235"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="343"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="301"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="337"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001134-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001134-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN57085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW25771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="398" mass="41303" checksum="C9E50AAB9EC6084B" modified="2016-02-17" version="1">MYVSNHRSRRIARASVFCVAAALAAMSSGAALASEQVSPELKFAMQRDLGIFPAQLPQYLQTEKLARTQAAAIEREFGAQFAGSWIERNQDGSFKVVAATSGARKSTTLGGVEVRNVRYSLKQLQASMDQLDAGANARVKGISKPLDGVQSWYVDAQTNSIVVKVDEGATDAGVDFVALSGADSAQVRIERSPGKLQTTANIIGGIEYSINNASLCSVGFSVTRGATKGFVTAGHCGTVNAVARIGGAQVGTFAARVFPGNDRAWVSLTSAQTLLPRVSNYSGGYITVRGSSEAAIGAAVCRSGRTTGYQCGTITAKNVTANYAEGAVRGLTNANACMGRGDSGGSWITSAGQAQGVMSGGNVQSNGNNCGIPASQRSSLFERLTPILSQYGLTLVTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFK2</accession>
    <name>A0A0S2DFK2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_1915</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57266">
        <property type="protein sequence ID" value="ALN57266"/>
        <property type="gene ID" value="GLE_1915"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1915"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1882"/>
    <dbReference type="OMA" id="VIAKYWG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="124"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="236"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="280"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="392"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="417"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="450" mass="47336" checksum="99FA58F5658BDEBF" modified="2016-02-17" version="1">MLGIGAVIGAGIFVLSGHAAAEHAGPAIVLSFVVAGIACALAGLCYAEFSAMLPVSGSAYSYSYATLGEFVAWFIGWNLVLEYLFAASTVAVGWSGYLNSLLTTFGVGLPASLSAAPLNMVDGAFVYTGGLVNLPAVVIVAALSGLCYVGITQSAFINTIIVAIKVVVITLFVAFAAKYVNPDNWVPFIPESQGPGKYGIDGVIRGASVVFFAYIGFDAVSTAAGEAKNPQRDMPIGILGSLVICTIIYIIVSGVLTGLLPYHMLSTPKPVATALEAYPALGWLKLVVEIGAIAGLSSVILVMLMGQPRIFYSMAKDGLLPQFFAKVHPKFQTPYVGTIIVGVFACILAGLFPINLLGELVSMGTLLAFATVCVGVLILRNTRPDLPRPFRVPLAVVVCPLGAAACLYLFWKPFSEHWHLMTGWTAIGMLIYFGYGYHNSKLRKAAGGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFM6</accession>
    <name>A0A0S2DFM6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947116.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1880"/>
    <dbReference type="EnsemblBacteria" id="ALN57232">
        <property type="protein sequence ID" value="ALN57232"/>
        <property type="gene ID" value="GLE_1880"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1880"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1851"/>
    <dbReference type="OMA" id="HEMANRF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="200" mass="21853" checksum="02131821BF22A859" modified="2016-02-17" version="1">MRKDDRYGRDDRPVPFDKLSMNTPAPQSRTYLITGMSGAGKSSVVRELIALGFDAIDLDSAQWSHWVDAAVDDALTPEQGRDWVWREDRVAALLAKPSRAPRLLAGTASNMAAFYDRFDAVVLLSASEDCLLQRLRERGAGEYGSTQAQRAAVRELIAQVEPLLRESADLTLDSSGPVAATVRDLLRALDLTAALPTPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFP2</accession>
    <name>A0A0S2DFP2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase, families S8 and S53</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_2063</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
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            <taxon>Proteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="GLE_2063"/>
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    <dbReference type="KEGG" id="lez:GLE_2063"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2028"/>
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    <dbReference type="Proteomes" id="UP000061569">
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
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        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
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        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase_S8" evidence="5">
        <location>
            <begin position="275"/>
            <end position="570"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="722" mass="74798" checksum="5F387E355549D648" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG33</accession>
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        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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        <lineage>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
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        <location>
            <begin position="276"/>
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        </location>
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            <begin position="108"/>
            <end position="135"/>
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            <begin position="341"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="379" mass="40661" checksum="64BFE649C186B79F" modified="2016-02-17" version="1">MTATLKHGRTLIWVAALAATGAGMYYWGRRSSAETPPPALAASAGEAAPSKAGAAPAASAAIARYDAGTARPLPPIDSPLRLVLPELQRRAASEPAAACRLAAEMEYCDSLRMRLAGAENNLDMFERQLERMPQDTAPQREQRQRMAESYQTMTDRLLTQSEHCAQVPPISAEQRAAYWRRAALAGQPAAMRHYASGNAFRYQELLDNLPGLATYRGEAESIARTAAQRGDARMLASLAYAYSPQRDGMRRGFLGQVVRPNAVESLALFLQLRDGLPAQDSDGPEAAPGGPGARGPRGGRFNSREMLDAQIRALTRDLSPEQVSQARERAAERAQSWSTPTAPAPPAPPGGAPSNAPPMFLMQGGFVPDVQRQECEGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGC7</accession>
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            <fullName evidence="1">Uncharacterized protein</fullName>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57686">
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        <property type="gene ID" value="GLE_2337"/>
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="61" mass="6670" checksum="6AFBEC650EC27B69" modified="2016-02-17" version="1">MHETSPFEGAGRMPADQSVSIRCRAPTRRLGWAALARRQDGCGVCKRSDHAGKYLLHASSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGG7</accession>
    <name>A0A0S2DGG7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2293</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57642">
        <property type="protein sequence ID" value="ALN57642"/>
        <property type="gene ID" value="GLE_2293"/>
    </dbReference>
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    <dbReference type="PATRIC" id="fig|69.6.peg.2258"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="40" mass="4470" checksum="A68504F0CF06480F" modified="2016-02-17" version="1">MRACAMGQDVPYGAAPRKVLDLVACDLKQAFFFGYFLLSR</sequence>
</entry>
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    <accession>A0A0S2DGJ0</accession>
    <name>A0A0S2DGJ0_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">SWIM zinc finger protein</fullName>
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    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2287</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947423.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2287"/>
    <dbReference type="EnsemblBacteria" id="ALN57636">
        <property type="protein sequence ID" value="ALN57636"/>
        <property type="gene ID" value="GLE_2287"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2287"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2252"/>
    <dbReference type="OMA" id="KFPCKHG"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
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        <location>
            <begin position="54"/>
            <end position="87"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="446" mass="48327" checksum="7171E236AAC677CF" modified="2016-02-17" version="1">MESALTAEQALALAPDGASAKAATGLASDRHWVSLGGDAEALWGECKGSGAKPYQAQVDLGALVTRCSCPSRKFPCKHALALLLMHARGGIAADARPAWVEEWLNSRRDRAEKKEQAAAKAVAAQAADPEAAAAAAAKREAARWKRIDQGTAELQRWIGDQLRRGLASFGAQQRAEWTAMAARMVDAQAPALSAQLLAATDAMAAGIAGAPAVVERFGLIWLLREAVVRRATLSPQRLADVRAALGWVYDKDDLSTLGESVSDRWIVQGQRIDERDDRLFERRVWLRGQASGRDALLHDYAYGGRGWEQQWLDGRAVEATLRFFPGSAPLRALALEQGAAQPAPRWSQPAADAIEAASLAFAANPWLQWWPLALADAIPLYENERWWLHTPAGRLPLALGDAAGWNLLARSGGRALQVMGEWDGRELRPLSAWRGEDAAHNWSLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGM9</accession>
    <name>A0A0S2DGM9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2384</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57733">
        <property type="protein sequence ID" value="ALN57733"/>
        <property type="gene ID" value="GLE_2384"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2384"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2346"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="84" mass="9531" checksum="CC120B2DB3557F3D" modified="2016-02-17" version="1">MSERQVREDFATLQATGTVPGKARLERIEFTDGWSDGAEFEVYFCLPASDGPGRGCERRNIGLSYQQREGRWRLFSVQAEQAVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGR6</accession>
    <name>A0A0S2DGR6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">CorA-like Mg2+ transporter protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Magnesium transporter CorA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_11965</name>
        <name evidence="7" type="ORF">GLE_2389</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947503.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57738">
        <property type="protein sequence ID" value="ALN57738"/>
        <property type="gene ID" value="GLE_2389"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2389"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2351"/>
    <dbReference type="OMA" id="GFVWAYR"/>
    <dbReference type="OrthoDB" id="822653at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="SSF143865"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="SSF144083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="312"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW26279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="338" mass="36964" checksum="56988DDD79DDD253" modified="2016-02-17" version="1">MRIADASYGSNEDGLIWGYRFVPGQPAQPISTDAVAAFLAAPADGDGRGFLWLHFSLSNTGSERYLRRALRMPDAFYDSLRSEVGSTRLELDDNALIAVVHDVLFDSSFDASEVGTTSLCIGPRLLVSARLRPLRSVDQLRAAVRSGQVFRSPVELLAHLLRDQASVLGEILRKCTVQVDRIEDRLLDNRIATDRKQLGALRRSLVRLQRLLAPEPTALFRLLNRPPDWIGRNDIGDLQQAAEEFSTAIGDSAALVERVKLIQEELAALVNEQTGRTLFVLTVVTVVALPINLVAGLFGMNVGGIPLAENPHGFLSVVIGLCVLTAVLAYAAFGRRRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGT7</accession>
    <name>A0A0S2DGT7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter, ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">ATP-binding cassette domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_12700</name>
        <name evidence="5" type="ORF">GLE_2529</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947611.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2529"/>
    <dbReference type="EnsemblBacteria" id="ALN57878">
        <property type="protein sequence ID" value="ALN57878"/>
        <property type="gene ID" value="GLE_2529"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2529"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2491"/>
    <dbReference type="OMA" id="VEGPRQW"/>
    <dbReference type="OrthoDB" id="1926714at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="55"/>
            <end position="62"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW26395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="321" mass="36370" checksum="A421A9A5F6C93141" modified="2016-02-17" version="1">MIEVERLSKTFAYHTKKEGLLGSIGNLFHRPTLHKQAVSEVSFRIEGGEIVGLLGPNGAGKSTLIKMLSGILYPTSGSARVAGYVPWERALAFRRSIGIVMGQRSQLWPDLPAMDSYLLNQRIYDVEETAFRRVIVELSGLLDVRRLLDIQVRRLSLGERIKLDLIGALLHSPRVVFLDEPTIGLDFAAQKSIRGFIRDYCDRFGATIVLTSHYSTDIEDLCRRVIVTHHGKLLYDGELVRIADRFSFAKIVRFRVRSAAAAVALPFDYALQEKPDGEYWIEARSEHVNEVIRVLLDRLEVEDLRIEHLPLERSIESLYVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH32</accession>
    <name>A0A0S2DH32_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase, short chain dehydrogenase/reductase family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">SDR family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_11785</name>
        <name evidence="2" type="ORF">GLE_2350</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947472.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2350"/>
    <dbReference type="EnsemblBacteria" id="ALN57699">
        <property type="protein sequence ID" value="ALN57699"/>
        <property type="gene ID" value="GLE_2350"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2350"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2312"/>
    <dbReference type="OMA" id="RAMTVYA"/>
    <dbReference type="OrthoDB" id="1186478at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="251" mass="27100" checksum="7A5D1017BBEA3D2D" modified="2016-02-17" version="1">MRKRILITGASSGLGRGMAREFAGLGRDLALCARRLDRLQTLKAELEAAHPGIRVAVRSLDVTDHDAVFRVFGELRDELGGLDRVVVNAGIGQGAPVGKGQFALNRAIVETNFLAALAQCEAAMETFRAAGQGHLVLISSMSAMRGLRGGLTAYAASKAGVAALAEGIRTDMLRKPSIRVSTVFPGYIRTEMNDGAPAAHTPFIIDEATGCRLLARAIEKEPNKAYVPWWPWAPLGWWMKRAPLSWVARLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH61</accession>
    <name>A0A0S2DH61_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ubiquinol oxidase subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">cyoA</name>
        <name evidence="15" type="ORF">FE772_11900</name>
        <name evidence="14" type="ORF">GLE_2377</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">C3</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the cytochrome c oxidase subunit 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947494.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2377"/>
    <dbReference type="EnsemblBacteria" id="ALN57726">
        <property type="protein sequence ID" value="ALN57726"/>
        <property type="gene ID" value="GLE_2377"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2377"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2338"/>
    <dbReference type="OMA" id="TAMNSFF"/>
    <dbReference type="OrthoDB" id="1654242at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070469">
        <property type="term" value="C:respirasome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009486">
        <property type="term" value="F:cytochrome bo3 ubiquinol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016682">
        <property type="term" value="F:oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04212">
        <property type="entry name" value="CuRO_UO_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045187">
        <property type="entry name" value="CcO_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002429">
        <property type="entry name" value="CcO_II-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010514">
        <property type="entry name" value="COX_ARM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034227">
        <property type="entry name" value="CuRO_UO_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011759">
        <property type="entry name" value="Cyt_c_oxidase_su2_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036257">
        <property type="entry name" value="Cyt_c_oxidase_su2_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006333">
        <property type="entry name" value="Cyt_o_ubiquinol_oxidase_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22888">
        <property type="entry name" value="PTHR22888"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00116">
        <property type="entry name" value="COX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06481">
        <property type="entry name" value="COX_ARM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000292">
        <property type="entry name" value="Ubi_od_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81464">
        <property type="entry name" value="SSF81464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01433">
        <property type="entry name" value="CyoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50857">
        <property type="entry name" value="COX2_CUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50999">
        <property type="entry name" value="COX2_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="9 10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="COX2_TM" evidence="13">
        <location>
            <begin position="19"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="COX2_CUA" evidence="12">
        <location>
            <begin position="131"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN57726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW26269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="349" mass="38206" checksum="ED3B0714234AA7D9" modified="2016-02-17" version="1">MNAIKSLLRPLLLAGALLPLAGCNTLLLNAPGDVARQQGDLIIVSTVLMLLIIVPVIALTLFFAWRYRASNTKATYKPDWDHSTQLELLIWAAPLLIIIVLGAITWVSTHTLDPYRPLDRIKAGQPVAADVKPLEIEVVALDWKWLFLYPEYNIATINEIAAPVDRPIKFKITASSVMNSFYIPALAGQIYAMPGMETQLHAVMNHPGEYEGFSANYSGAGFSHMRFKFHGLDQAGFDRWVQSNRAGGQTLERAGYLELEKPSEKEPVRRYSAVAPGLYKAILNRCVDASKMCMDEMMMIDANGGLGNSANALAPRRRGDLRGGPVVLSAMCVTEPSAVPSWGVATLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHI6</accession>
    <name>A0A0S2DHI6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Carbonic anhydrase</fullName>
            <ecNumber evidence="3 6">4.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Carbonate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BV903_18780</name>
        <name evidence="9" type="ORF">FE772_13390</name>
        <name evidence="7" type="ORF">GLE_2673</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Reversible hydration of carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>H(+) + hydrogencarbonate = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="3 6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000052">
        <property type="protein sequence ID" value="OPD62400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947723.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000052.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2673"/>
    <dbReference type="EnsemblBacteria" id="ALN58021">
        <property type="protein sequence ID" value="ALN58021"/>
        <property type="gene ID" value="GLE_2673"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62400">
        <property type="protein sequence ID" value="OPD62400"/>
        <property type="gene ID" value="BV903_18780"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2673"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2632"/>
    <dbReference type="OMA" id="PANEIIG"/>
    <dbReference type="OrthoDB" id="1841447at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015976">
        <property type="term" value="P:carbon utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015892">
        <property type="entry name" value="Carbonic_anhydrase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002">
        <property type="entry name" value="PTHR11002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="SSF53056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00704">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00705">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD62400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW26507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="221" mass="24996" checksum="BF62309DC6C5319F" modified="2016-02-17" version="1">MNPLDDLLERNREWSERINAEDPDFFARLSKQQAPEYLWIGCSDSRVPANQIIDMAPGEVFVHRNIANVVVHTDLNCLSVIQYAVDVLKVKHILVVGHYGCGGVHAALHGTRVGLADNWLRHVSDVADKHSECMNHAHESERHDRLCELNAIEQVFNVCMTTIVRDAWSRDQPLSVHGWVYSLRNGRVHDTGMNVHSFKSLQPAYERALARVHSTHGGSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHJ0</accession>
    <name>A0A0S2DHJ0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rrf2 family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator, Rrf2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_02255</name>
        <name evidence="3" type="ORF">FE772_11985</name>
        <name evidence="1" type="ORF">GLE_2394</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000004">
        <property type="protein sequence ID" value="OPD65606.1"/>
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        <property type="gene ID" value="BV903_02255"/>
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        </source>
    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
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</entry>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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            <end position="22"/>
        </location>
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            <begin position="23"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="141" mass="15413" checksum="8B8358F928CB0B59" modified="2016-02-17" version="1">MRNSIATSPRLWTAIALTVALAGCATRPAPDFGGRWKPVNRYAEVPDEIPLHKSYVYYPSPMDGTLKNMLTRWSKDANLKLDYQHYSDFTLFQGVSQINTTSLPDAISQLNSAYSGHGVSISREGEQIVVRSSGAPAPASP</sequence>
</entry>
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    <accession>A0A0S2DHR6</accession>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
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    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW26655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="303" mass="33455" checksum="93A5C7CAEA6D915C" modified="2016-02-17" version="1">MTIGEYSQIYRGKRVVEFRMGATPAGGDVVYRLTQDYDSEESQRALLDDFLSKVDPAELETLIVGAWSEAHDEGPQGYIDALIEYRAKLPKLTALFFGDMTYEDCEISWITQTSYNPLLAAFPQLQSLRVRGSTSLELQAFSHDALEELAIECGGLPSQIVDAVAGSTLPALKHLELWLGSDNYGFDGGLAPYQNLLAKIGPERLRYLGLRDSEISDEVAVWLAQQPWLGSLQTLDLSLGTIGDVGAQALAESPNLGALERIDLSHHYISEEWQAKLRALPCQVVLDDPEEEDDGDRYVAVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHU1</accession>
    <name>A0A0S2DHU1_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">Acyl-CoA ligase</fullName>
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    <gene>
        <name evidence="3" type="ORF">GLE_2522</name>
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    <organism evidence="3 4">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="STRING" id="69.GLE_2522"/>
    <dbReference type="EnsemblBacteria" id="ALN57871">
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        <property type="gene ID" value="GLE_2522"/>
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    <dbReference type="KEGG" id="lez:GLE_2522"/>
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    <dbReference type="OMA" id="AVWSGDT"/>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
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        </location>
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        <location>
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        </location>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN57871.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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    </evidence>
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</entry>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="GLE_2644"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2644"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="95" mass="10259" checksum="AE6EDAEB0EC802EB" modified="2016-02-17" version="1">MNADDSVRKADGVRWRPVPQAECLMVFSPHSGRIHWLALDTWLLFELCDGRNVDAVARGYAELAGDKLGGGDARARAERGLASLLGSRLIEAAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHX1</accession>
    <name>A0A0S2DHX1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_19775</name>
        <name evidence="4" type="ORF">FE772_13590</name>
        <name evidence="2" type="ORF">GLE_2714</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000058">
        <property type="protein sequence ID" value="OPD62175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947760.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000058.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58062">
        <property type="protein sequence ID" value="ALN58062"/>
        <property type="gene ID" value="GLE_2714"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62175">
        <property type="protein sequence ID" value="OPD62175"/>
        <property type="gene ID" value="BV903_19775"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2714"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2673"/>
    <dbReference type="OrthoDB" id="2102264at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595170" evidence="1">
        <location>
            <begin position="20"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="59" mass="6201" checksum="DF89BF4D91B333B6" modified="2016-02-17" version="1">MKSNRFLRYAAIVSLLACAACKPQSIPYFDDAHVDLSARAAPAAVDAAKVAVASVRTAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI10</accession>
    <name>A0A0S2DI10_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Energy transducer TonB</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="11">TonB family C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FE772_14690</name>
        <name evidence="11" type="ORF">GLE_2946</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TonB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947931.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2946"/>
    <dbReference type="EnsemblBacteria" id="ALN58294">
        <property type="protein sequence ID" value="ALN58294"/>
        <property type="gene ID" value="GLE_2946"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2946"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2908"/>
    <dbReference type="OMA" id="YSPQLAC"/>
    <dbReference type="OrthoDB" id="2074833at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242447" evidence="9">
        <location>
            <begin position="21"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_C" evidence="10">
        <location>
            <begin position="45"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN58294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW28768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="137" mass="14219" checksum="0BA9CE3CC7F881B4" modified="2016-02-17" version="1">MNLKRRLLAPSLAFAFAAMAAGCGQRAAEEPIVPSTPLRAVDTPPPDYPLEIGCDQVGGKVVLQLTVGPEGKPTRARVLTGSGVPELDAAATKGVQRWRFEAATRNGKPVATDIQVPVTFHAPAERPAHCGQASGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI70</accession>
    <name>A0A0S2DI70_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">TIM barrel protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Xylose isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_13065</name>
        <name evidence="5" type="ORF">GLE_2603</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the hyi family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2603"/>
    <dbReference type="EnsemblBacteria" id="ALN57951">
        <property type="protein sequence ID" value="ALN57951"/>
        <property type="gene ID" value="GLE_2603"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2603"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2563"/>
    <dbReference type="OMA" id="GHYHTGG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026040">
        <property type="entry name" value="HyI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006241">
        <property type="entry name" value="HyI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="4">
        <location>
            <begin position="107"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR006241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR006241-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW26455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="292" mass="32077" checksum="60FC64F5AD4911EE" modified="2016-02-17" version="1">MSFMNPKITRRNAIRAAAMAGLGLTAAAVAPGIAAPAALKGRLKHSVARWTFPKQSVAELCRTVKDIGFSAIDLVGPEDWPTLKAHGVFSSMCNGAELGLKNGFAGKEFHDQLVERYTRHIDLVADAGYRNLICFSGNRNGMDPQQGLANAEAGLKRILGHAEKRGVVLVMELLNSRVDHPDYLCDRSAWGVALCERIGSDHFGLLYDIYHMQIMEGDIIATIGKHHSWFKHYHTAGVPGRHEIGANQELNYPAICRAIRDTGFDGYLAQEFMPEAPDPVESLREAIRLCDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIX7</accession>
    <name>A0A0S2DIX7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nucleotide sugar dehydrogenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Nucleotide sugar dehydrogenase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_15020</name>
        <name evidence="5" type="ORF">GLE_3005</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947974.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3005"/>
    <dbReference type="EnsemblBacteria" id="ALN58353">
        <property type="protein sequence ID" value="ALN58353"/>
        <property type="gene ID" value="GLE_3005"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3005"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2966"/>
    <dbReference type="OMA" id="GHCLPID"/>
    <dbReference type="OrthoDB" id="295459at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028359">
        <property type="entry name" value="UDP_ManNAc/GlcNAc_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500136">
        <property type="entry name" value="UDP_ManNAc_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="SSF52413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh_C" evidence="4">
        <location>
            <begin position="322"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW26763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="429" mass="47048" checksum="E4B491F11C0A5AFB" modified="2016-02-17" version="1">MAQHDNSIAHARIGVIGLGYVGLPLALEFGKRYDTVGYDIDPVRVAQLSTGEDRHHEHGADEIRAAARLRFSAALEDLDDRDVFVVTVPTPVDEHKRPDFTPLILASRALGGVLKAGGTVIYESTVYPGATEEICIPELERVSGLRCNVDFFVGYSPERINPGDRQRRLVDIPKVTSGSSPAAAERVDALYRSIIPAGTHRASSLRVAEASKVIENTQRDANIALVNEFALIFQRLGIDTTEVLEAAGTKWNFLPFRPGLVGGHCIGVDPYYLIQKAQSAGYYPDILLACRRINDAMGGFVAAEVIKRMIQRGVAIAGSRILILGLTFKENCADLRNTRVIDLAREFGEYRARVEICDPWANAEEARREYGLDMVEAPERGAYDAVVIAVAHEQFRTLGAAGARAYGKPGALLYDIKSLYPREDVDARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIZ2</accession>
    <name>A0A0S2DIZ2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3021</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58369">
        <property type="protein sequence ID" value="ALN58369"/>
        <property type="gene ID" value="GLE_3021"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3021"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2982"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="162" mass="16960" checksum="ABAD7E0DDB338247" modified="2016-02-17" version="1">MNKTVDATTPADAGPIRVLHFAMRARRHDNACARRLRALRRSAAHCLLLLALLADLIALPAWSMGLPFAAPAASARCERAPSADATLAAAAQMTADFGDPSPHAPDLLDAASATGEHAECEPCVLPPSLRTPAPSRHNAALPELRQAARATPHGPDPRPPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ37</accession>
    <name>A0A0S2DJ37_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">LapA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BV903_02745</name>
        <name evidence="9" type="ORF">FE772_14580</name>
        <name evidence="7" type="ORF">GLE_2923</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000005">
        <property type="protein sequence ID" value="OPD65453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947914.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58271">
        <property type="protein sequence ID" value="ALN58271"/>
        <property type="gene ID" value="GLE_2923"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65453">
        <property type="protein sequence ID" value="OPD65453"/>
        <property type="gene ID" value="BV903_02745"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2923"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2885"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010445">
        <property type="entry name" value="LapA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06305">
        <property type="entry name" value="LapA_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="LapA_dom" evidence="6">
        <location>
            <begin position="22"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD65453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW26696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="94" mass="9501" checksum="0E45E4CFA2965D77" modified="2016-02-17" version="1">MRLIRVLIAVLCLAAGAVLGALNRQSVSIDLGFGFVPATSLGIVLIVSLLAGALIGGLAISASVVLPLRRRLARAERGRADSGAGLPAVTTVEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ95</accession>
    <name>A0A0S2DJ95_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 6">Elongation factor Ts</fullName>
            <shortName evidence="5">EF-Ts</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">tsf</name>
        <name evidence="10" type="ORF">BV903_17675</name>
        <name evidence="11" type="ORF">FE772_16600</name>
        <name evidence="9" type="ORF">GLE_3363</name>
    </gene>
    <organism evidence="9 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">C3</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the EF-Ts family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000048">
        <property type="protein sequence ID" value="OPD62506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948239.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000048.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3363"/>
    <dbReference type="EnsemblBacteria" id="ALN58709">
        <property type="protein sequence ID" value="ALN58709"/>
        <property type="gene ID" value="GLE_3363"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62506">
        <property type="protein sequence ID" value="OPD62506"/>
        <property type="gene ID" value="BV903_17675"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3363"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3313"/>
    <dbReference type="OMA" id="DAGMMDC"/>
    <dbReference type="OrthoDB" id="1405357at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00050">
        <property type="entry name" value="EF_Ts"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036402">
        <property type="entry name" value="EF-Ts_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001816">
        <property type="entry name" value="Transl_elong_EFTs/EF1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014039">
        <property type="entry name" value="Transl_elong_EFTs/EF1B_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018101">
        <property type="entry name" value="Transl_elong_Ts_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11741">
        <property type="entry name" value="PTHR11741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00889">
        <property type="entry name" value="EF_TS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="SSF46934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54713">
        <property type="entry name" value="SSF54713"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00116">
        <property type="entry name" value="tsf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01126">
        <property type="entry name" value="EF_TS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01127">
        <property type="entry name" value="EF_TS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 6" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="4 5 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF_TS" evidence="8">
        <location>
            <begin position="71"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Involved in Mg(2+) ion dislocation from EF-Tu" evidence="5">
        <location>
            <begin position="80"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN58709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD62506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW27018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="293" mass="30920" checksum="C22077BF2BBABFAD" modified="2016-02-17" version="1">MAEITASLVKELRERTGAGMMECKKALTETNGDLEAAVEWLRKSGAVKAEKKADRVAAEGRIAVAQDGGKAVLVEINSETDFVAKDSNFLAFTDAVAQVALTSGAADVEALKAAKLPTGESVEETRAAVIAKVGENLQVRRLVRLESANNVAAYVHGGKIGVLIELKGGDAELARGIAMHVAAMNPPHIKASDVPAEFVAKEKEIELAKMSDKDKAKPADILEKIISGKIAKIVNEVTLYGQPYVLNSDQTVEQAVKAAGADVVSMTRLVVGEGIEKQTDDFAAEVMKQAGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJB7</accession>
    <name>A0A0S2DJB7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">KfrA_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3019</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947986.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58367">
        <property type="protein sequence ID" value="ALN58367"/>
        <property type="gene ID" value="GLE_3019"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3019"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2980"/>
    <dbReference type="OrthoDB" id="399615at1236"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021104">
        <property type="entry name" value="KfrA_DNA-bd_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11740">
        <property type="entry name" value="KfrA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KfrA_N" evidence="2">
        <location>
            <begin position="41"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="177" mass="19482" checksum="D50F635974D0925F" modified="2016-02-17" version="1">MATDQDALWRIRQSLAEEGRLGGARGSQERVPLDQGQLDDIAWRMLRAGVQPTVEAIRAVYGSGSPNRLHPMLRRFYAGLATRLQLAPLADEVPVPLRQLWLQALDLASDAVRERHDAQAEELRQRVAELERREAALERKLKRLRRDGAAPRPPAAAAQAEPAAPANPPSGDEPSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJD9</accession>
    <name>A0A0S2DJD9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Poly(A) polymerase I</fullName>
            <shortName evidence="5">PAP I</shortName>
            <ecNumber evidence="5">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 11" type="primary">pcnB</name>
        <name evidence="12" type="ORF">FE772_15790</name>
        <name evidence="11" type="ORF">GLE_3179</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide</text>
            <dbReference type="Rhea" id="RHEA:11332"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17347"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="ChEBI" id="CHEBI:173115"/>
            <dbReference type="EC" id="2.7.7.19"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948101.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3179"/>
    <dbReference type="EnsemblBacteria" id="ALN58525">
        <property type="protein sequence ID" value="ALN58525"/>
        <property type="gene ID" value="GLE_3179"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3179"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3134"/>
    <dbReference type="OMA" id="THKNEFI"/>
    <dbReference type="OrthoDB" id="2018439at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004652">
        <property type="term" value="F:polynucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006378">
        <property type="term" value="P:mRNA polyadenylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05398">
        <property type="entry name" value="NT_ClassII-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00957">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010206">
        <property type="entry name" value="PolA_pol_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025866">
        <property type="entry name" value="PolyA_pol_arg_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032828">
        <property type="entry name" value="PolyA_RNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12626">
        <property type="entry name" value="PolyA_pol_arg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12627">
        <property type="entry name" value="PolyA_pol_RNAbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01942">
        <property type="entry name" value="pcnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PolyA_pol" evidence="8">
        <location>
            <begin position="47"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="PolyA_pol_RNAbd" evidence="10">
        <location>
            <begin position="202"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="PolyA_pol_arg_C" evidence="9">
        <location>
            <begin position="318"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="407"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="414"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN58525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW26885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="455" mass="51022" checksum="BB63F2DB5E25FEA7" modified="2016-02-17" version="1">MQADNISSHIQTSLRVIPRDQHNVSRKDISPNALRVLYRLRDSGFGAYLVGGAVRDILVGGHPKDFDVATDATPEQVKGLFRNCRLIGRRFRLAHVVYGREIIEVATFRANIDDGSGDRETDDGGRLLRDNVYGSIEDDAVRRDFTANALYYAVEDFSVRDYVGGFEDVQNRLMRLIGDPETRYREDPVRMLRAVRLAAKLGFEIERDTAAPIPKLAPLLAEAAPARLFEECLKLFLSGHAVESFLGLERYGLLPALLPESAAALKSNRSGALRRMVLEGLKGTDARVAADEPVSPAFLFALLLWPAYCRDLMGLQAQGVHTAEAQRRAADRVTLHQLATIALPRRFSLPMQEIWLLQSRFQQRQRKRVFRLLSHPRFRAAFDFLSLRTAASDEHSADVEFWREAQQHPNESLAQHEAQHERAGEDGGDEEGGDGQAPRKRRRRRRGAPVGGAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJT7</accession>
    <name>A0A0S2DJT7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58697">
        <property type="protein sequence ID" value="ALN58697"/>
        <property type="gene ID" value="GLE_3351"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3351"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3301"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="55" mass="6109" checksum="CC3EE2A213F8E487" modified="2016-02-17" version="1">MLLRPRRRAVAAADLSNRFLPLAPRPPAVRCRGLDQPRFSAARSRSPQRTQANAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJW1</accession>
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        <submittedName>
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        </submittedName>
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    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
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        </lineage>
    </organism>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58917">
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    <dbReference type="PATRIC" id="fig|69.6.peg.3517"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="53" mass="5908" checksum="0C78FEC3D1920D08" modified="2016-02-17" version="1">MSEQTRLIGRMVAIESEQMEGAEQNAAFVAATTYRRTSPFNEIDFADNGDQIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK44</accession>
    <name>A0A0S2DK44_LYSEN</name>
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        <submittedName>
            <fullName evidence="7">Non-ribosomal peptide synthase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_3675</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP013140">
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        <property type="gene ID" value="GLE_3675"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3675"/>
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    </dbReference>
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        <property type="project" value="InterPro"/>
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        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="match status" value="7"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ACP-like_sf"/>
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        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
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        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
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        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
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        <property type="entry name" value="NRPS_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
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        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
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        <property type="match status" value="7"/>
    </dbReference>
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        <property type="match status" value="10"/>
    </dbReference>
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        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="7"/>
    </dbReference>
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        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="7"/>
    </dbReference>
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        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="7"/>
    </dbReference>
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        <property type="entry name" value="NRPS-para261"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="6"/>
    </dbReference>
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        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="7"/>
    </dbReference>
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    <keyword evidence="2 5" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="959"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="2015"/>
            <end position="2089"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
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            <end position="3627"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="4605"/>
            <end position="4680"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
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            <end position="6151"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
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        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="8712"/>
            <end position="8786"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="5">
        <location>
            <position position="994"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="5">
        <location>
            <position position="2050"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="5">
        <location>
            <position position="3587"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="5">
        <location>
            <position position="4640"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="5">
        <location>
            <position position="6112"/>
        </location>
    </feature>
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        <location>
            <position position="7662"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="5">
        <location>
            <position position="8747"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="9289" mass="1006614" checksum="1E5D431F79669E11" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK59</accession>
    <name>A0A0S2DK59_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Helix-turn-helix domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    <organism evidence="2 4">
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        <lineage>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="5"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="187" mass="20585" checksum="F65B774C00FB4C75" modified="2016-02-17" version="1">MAARLRSLRKKYGWTIEALAQQTGLTKSYLSKVERGLSVPSIAVALKLAHAFKIDVEQLFSDATGERASYTVVRAGERTPIARSGKASKPAYEGIATQLSHKRLLPFMMYPPKDFATSEFKEHAGEELMFVHKGEVEVMLAGQSVRLGVGDSLYFDAQIPHRVRSAGAQQAQVLIVVHDAQAEAERD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKE4</accession>
    <name>A0A0S2DKE4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cupin-like domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Pass1-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_18015</name>
        <name evidence="2" type="ORF">GLE_3664</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948453.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3664"/>
    <dbReference type="EnsemblBacteria" id="ALN59008">
        <property type="protein sequence ID" value="ALN59008"/>
        <property type="gene ID" value="GLE_3664"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3664"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3608"/>
    <dbReference type="OMA" id="YPALWWH"/>
    <dbReference type="OrthoDB" id="1885303at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="1">
        <location>
            <begin position="114"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="336" mass="37075" checksum="BD5C8BE9AB3DA9F4" modified="2016-02-17" version="1">MPPAVDAIEELHGIDAAALPQELLQPTRPYVLRGLAAHWPLTLAGASAQAGAAYLKQFASDAPVTVSVAPPQADGRIDYRPDLLGFGFAQQKAPLAAVLDALLHHADDPAPPTIYVGSTTIDTWLPGLRERNDLGFGAVQPLASIWIGNRTRIPAHQDVPDNIACVVAGRRRVTLFPPGQLRNLYIGPLDRTPAGQAVSLVDFAAPDYDRHPDFAEAMRHARVAELGPGDAVLIPSMWWHHMQALDSYNVLVNYWWRQSPRWMDTPMNALLHAIMSVRDLPPAQREIWREAFRHYVFDADAQTSAHIPETMRGALAPLDEARARELRARLLQGLNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKH9</accession>
    <name>A0A0S2DKH9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ssb</name>
        <name evidence="7" type="ORF">FE772_18305</name>
        <name evidence="6" type="ORF">GLE_3716</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948496.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3716"/>
    <dbReference type="EnsemblBacteria" id="ALN59060">
        <property type="protein sequence ID" value="ALN59060"/>
        <property type="gene ID" value="GLE_3716"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3716"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3661"/>
    <dbReference type="OMA" id="GQMQERT"/>
    <dbReference type="OrthoDB" id="1942216at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="108"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Important for interaction with partner proteins" evidence="2">
        <location>
            <begin position="189"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="172"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW27299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="194" mass="19880" checksum="B81C8AE9F4C59E74" modified="2016-02-17" version="1">MARGINKVILVGNLGNDPETKYTQGGMAVTTISLATTSVRKDRDGNNQERTEWHRVKLFGKLGEIAGEYLRKGRQVYIEGSIRYDKFTGQDGVEKYFTDIIADEMQMLGGGGEGGGGGGGRSEGGGRGEFRGGGGGGGERPARSAGGGGYGGGGGGGGSGGGYGGGRDSGQRREAPPAKSNDFGDDFADDDIPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKK1</accession>
    <name>A0A0S2DKK1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_18345</name>
        <name evidence="1" type="ORF">GLE_3724</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948501.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59068">
        <property type="protein sequence ID" value="ALN59068"/>
        <property type="gene ID" value="GLE_3724"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3724"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3669"/>
    <dbReference type="OrthoDB" id="2074885at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="79" mass="8906" checksum="D49709659E12AEB2" modified="2016-02-17" version="1">MPRRTAPATPADYVLLPADAYHGLQAFRDELIGIAQTIDPATPSPEIRKPEQSRRRALARVFRLWADQVHGNLETIRSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL07</accession>
    <name>A0A0S2DL07_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_18970</name>
        <name evidence="2" type="ORF">GLE_3860</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948601.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3860"/>
    <dbReference type="EnsemblBacteria" id="ALN59203">
        <property type="protein sequence ID" value="ALN59203"/>
        <property type="gene ID" value="GLE_3860"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3860"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3799"/>
    <dbReference type="OrthoDB" id="1785082at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="200"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="309" mass="34674" checksum="36385C7179604BC1" modified="2016-02-17" version="1">MSVHHHRIRFAEHLDLGAGAHPGPSLDLNRPWSPTPAGLHLVCASGRAVQLDLPPGWLSLWLPLQGPLRLEAADSAWDLAPGHLQVWRDGRVRSGARGPCWWLCLCGPEAAWKPHLAGAPQALGSELFPWEGVAARDARRLLVRLARLGARPTELAASGPTLLRTLAELLREEQRELLERLARCSGRTLRRRQQTLLRLLRVQHLIRRHPDVRLDLGRLARSASYSPCHLIRIYRDVFDETPTEYAARLRSDRAWRMVRDTRMPVCEITEALGFESQSAFCRAFKNSFGVTATQARRAEGARLARGRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLE2</accession>
    <name>A0A0S2DLE2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_20000</name>
        <name evidence="3" type="ORF">GLE_4076</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948764.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59418">
        <property type="protein sequence ID" value="ALN59418"/>
        <property type="gene ID" value="GLE_4076"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4076"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4018"/>
    <dbReference type="OrthoDB" id="2157832at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242336" evidence="2">
        <location>
            <begin position="30"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="103" mass="11387" checksum="DCB431C6D6B304AC" modified="2016-02-17" version="1">MFKSRLLPPVLLATVTAISALLPISSAFAACNDCPWLFVRCMSRADTPEKEQACEESRQLCEETFCNNPRAARLSASPAIVENPLPQARDLADRRPQARRSAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLF6</accession>
    <name>A0A0S2DLF6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="13">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLE_4092</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948776.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4092"/>
    <dbReference type="EnsemblBacteria" id="ALN59434">
        <property type="protein sequence ID" value="ALN59434"/>
        <property type="gene ID" value="GLE_4092"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4092"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4034"/>
    <dbReference type="OMA" id="GHWAVNA"/>
    <dbReference type="OrthoDB" id="71288at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015420">
        <property type="term" value="F:ABC-type vitamin B12 transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010101">
        <property type="entry name" value="B12_transptr_BtuB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01779">
        <property type="entry name" value="TonB-B12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0626">Porin</keyword>
    <keyword evidence="13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="5 9" id="KW-0798">TonB box</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595219" evidence="10">
        <location>
            <begin position="31"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="12">
        <location>
            <begin position="51"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="11">
        <location>
            <begin position="222"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN59434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="628" mass="68424" checksum="91C63D5CE5E1B52F" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLG5</accession>
    <name>A0A0S2DLG5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">50S ribosomal protein L25</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">General stress protein CTC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">rplY</name>
        <name evidence="6" type="synonym">ctc</name>
        <name evidence="10" type="ORF">BV903_21145</name>
        <name evidence="11" type="ORF">FE772_18755</name>
        <name evidence="9" type="ORF">GLE_3808</name>
    </gene>
    <organism evidence="9 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">C3</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000067">
        <property type="protein sequence ID" value="OPD61944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948570.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000067.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3808"/>
    <dbReference type="EnsemblBacteria" id="ALN59151">
        <property type="protein sequence ID" value="ALN59151"/>
        <property type="gene ID" value="GLE_3808"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61944">
        <property type="protein sequence ID" value="OPD61944"/>
        <property type="gene ID" value="BV903_21145"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3808"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3751"/>
    <dbReference type="OMA" id="HVDFYEV"/>
    <dbReference type="OrthoDB" id="1673077at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00495">
        <property type="entry name" value="Ribosomal_L25_TL5_CTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01336">
        <property type="entry name" value="Ribosomal_L25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01334">
        <property type="entry name" value="Ribosomal_L25_CTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_L25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029751">
        <property type="entry name" value="Ribosomal_L25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_L25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020057">
        <property type="entry name" value="Ribosomal_L25_b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037121">
        <property type="entry name" value="Ribosomal_L25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001021">
        <property type="entry name" value="Ribosomal_L25_long"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020055">
        <property type="entry name" value="Ribosomal_L25_short"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01386">
        <property type="entry name" value="Ribosomal_L25p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14693">
        <property type="entry name" value="Ribosomal_TL5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="SSF50715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00731">
        <property type="entry name" value="bL25_bact_ctc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_TL5_C" evidence="8">
        <location>
            <begin position="102"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="190"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN59151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD61944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW27378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="219" mass="24236" checksum="7E27B21C9A7F83F1" modified="2016-02-17" version="1">MSEHTIKATGRNVEGKGASRRLRHAASIPAIVYGGSAAPQPIQLEHEKIWLASQHEWFYSSILNLDVDGKVEQVLLRDMQRHPFKQIIMHLDFQRVDANQALRVAVPLHFLNEDKSPAGKSADVVVTHELNEVEVSCLPKDLPEFIEIDLSELKVGDIVHLSDLKLPKGVEIPELKLGKEHDVAIVIAKHGKEEAEPAEDAPAADVPAAKVAKKDEDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLP9</accession>
    <name>A0A0S2DLP9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 11">Chaperone protein ClpB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11 13" type="primary">clpB</name>
        <name evidence="14" type="ORF">FE772_20100</name>
        <name evidence="13" type="ORF">GLE_4098</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">C3</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homohexamer. The oligomerization is ATP-dependent.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homohexamer; The oligomerization is ATP-dependent.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948780.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4098"/>
    <dbReference type="EnsemblBacteria" id="ALN59440">
        <property type="protein sequence ID" value="ALN59440"/>
        <property type="gene ID" value="GLE_4098"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4098"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4040"/>
    <dbReference type="OMA" id="SKMMQGE"/>
    <dbReference type="OrthoDB" id="44062at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017730">
        <property type="entry name" value="Chaperonin_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03346">
        <property type="entry name" value="chaperone_ClpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Clp R" evidence="12">
        <location>
            <begin position="3"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="412"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN59440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW27597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="861" mass="94901" checksum="6B9701E0C19727A4" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLW0</accession>
    <name>A0A0S2DLW0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD-superfamily hydrolase, subfamily IB</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Haloacid dehalogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_04550</name>
        <name evidence="3" type="ORF">FE772_20900</name>
        <name evidence="1" type="ORF">GLE_4269</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000008">
        <property type="protein sequence ID" value="OPD65193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948917.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000008.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4269"/>
    <dbReference type="EnsemblBacteria" id="ALN59610">
        <property type="protein sequence ID" value="ALN59610"/>
        <property type="gene ID" value="GLE_4269"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65193">
        <property type="protein sequence ID" value="OPD65193"/>
        <property type="gene ID" value="BV903_04550"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4269"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4207"/>
    <dbReference type="OMA" id="ISGYVWI"/>
    <dbReference type="OrthoDB" id="1472357at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD65193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="250" mass="26980" checksum="6C83E516973AAE98" modified="2016-02-17" version="1">MSLRPAAAGRFPAVREGAPLVVFDFDHTLYDGDSGSHLFAWLIKRSWWRMALALLITPLAGPMVAWLRTRRVGISAYVWVGTVGMSGARTLDAAIDRYVAGHTEQIRARLLPIALDVLHRHREQGDQVVVATGAPPELARAILAFVAHEDVPVVGTLVGPRLGALGARRHCHSHMKMTMLREAGFTAPVESAYSDSSADLPLLQAARKPVVVNPKARRVEMFQRVLPPGTPILNWGCPGRGGEPVGSAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLZ1</accession>
    <name>A0A0S2DLZ1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Membrane protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Proteolipid membrane potential modulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">YqaE/Pmp3 family membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BV903_07755</name>
        <name evidence="8" type="ORF">FE772_20420</name>
        <name evidence="6" type="ORF">GLE_4164</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">C3</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
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            <authorList>
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
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                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Feng T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <property type="gene ID" value="BV903_11695"/>
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            <dbReference type="EMBL" id="QCW27803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="62" mass="6798" checksum="A3B864DBEE44BF4A" modified="2016-02-17" version="1">MLPSVEAHCPYCGEPIELLVDDSAGDQRYIEDCQVCCRPIVVAVSVDEDGEPRVDVFAENEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM90</accession>
    <name>A0A0S2DM90_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4303</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59644">
        <property type="protein sequence ID" value="ALN59644"/>
        <property type="gene ID" value="GLE_4303"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4303"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4242"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="46" mass="4983" checksum="BD7D33EFEC40D88E" modified="2016-02-17" version="1">MKTAAAPALERRCAAAKIRNGVVERRRHAADARGDQPHSESDSEPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM97</accession>
    <name>A0A0S2DM97_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_21545</name>
        <name evidence="1" type="ORF">GLE_4410</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59751">
        <property type="protein sequence ID" value="ALN59751"/>
        <property type="gene ID" value="GLE_4410"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4410"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4349"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="180" mass="19392" checksum="43764834F1BB6B3C" modified="2016-02-17" version="1">MECSDRVSMRNRLFRIAMSTVFLVGCGTSPHKSAVEKLDARILIQSPAQLGGKGIDQVVGSLQARYGVALGTSLSPLVNARQSITLDDGTVIVQTLTDINAVGDAARDVRVDVAAQPCLPIARAAAWIHARRLSATPGSEVISGHVDYRFEDAQVRIDLTGEFGGKECLRVIEIYRQSQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMA4</accession>
    <name>A0A0S2DMA4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">C-5 sterol desaturase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Fatty acid hydroxylase superfamily</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Sterol desaturase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_11805</name>
        <name evidence="5" type="ORF">FE772_21425</name>
        <name evidence="3" type="ORF">GLE_4385</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000028">
        <property type="protein sequence ID" value="OPD63730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949011.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000028.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4385"/>
    <dbReference type="EnsemblBacteria" id="ALN59726">
        <property type="protein sequence ID" value="ALN59726"/>
        <property type="gene ID" value="GLE_4385"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63730">
        <property type="protein sequence ID" value="OPD63730"/>
        <property type="gene ID" value="BV903_11805"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4385"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4324"/>
    <dbReference type="OMA" id="HSSQHYN"/>
    <dbReference type="OrthoDB" id="2048011at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="2">
        <location>
            <begin position="81"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD63730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW27823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="281" mass="32691" checksum="77AE0A73DA5782E6" modified="2016-02-17" version="1">MEEWILLALAPVFLALIALEAWYWRKRRPGQYSLRDTLSNAALALMHQASDAIAWLLVIGLYYAVYAHRLFDLPASVWTIAALFVAQDFFYYWFHRASHRVRWLWASHVTHHSSERLNLSTAFRQSLTYPISGMWVFWLPLAWIGFEPKHIVAVVAINLAFQFFVHTEAVGKLGWLEKVFNTPSHHRVHHARNPRYIDRNYAGVLIVWDKLFGTYVEEDAATPCEYGIVGQIRSHNPIRLTFHEWIAMFADAWRARGLRGALGQLFGPPERSLAHLERVRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMH2</accession>
    <name>A0A0S2DMH2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4461</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59802">
        <property type="protein sequence ID" value="ALN59802"/>
        <property type="gene ID" value="GLE_4461"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4461"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4398"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="52" mass="5189" checksum="4B3DCE765CBAA700" modified="2016-02-17" version="1">MSAPLSPAAADTCHGRDMAAPARGRGFAPAQRKTAAAGNPGDGRLRRAASAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMK3</accession>
    <name>A0A0S2DMK3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Inner membrane protein YbcI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948822.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4145"/>
    <dbReference type="EnsemblBacteria" id="ALN59487">
        <property type="protein sequence ID" value="ALN59487"/>
        <property type="gene ID" value="GLE_4145"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4145"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4087"/>
    <dbReference type="OMA" id="FTVWIPL"/>
    <dbReference type="OrthoDB" id="1667936at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007404">
        <property type="entry name" value="YdjM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04307">
        <property type="entry name" value="YdjM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="197" mass="20917" checksum="2901A402F8D7A36D" modified="2016-02-17" version="1">MPTVMTHAVVPLALGLALGRQRISPRLLAAGALAAMLPDADVVAFKLGIAYADDFGHRGASHSFAFAAALAALGALAAPWLRAPRWRAAWWLFLCAASHPLLDALTDGGLGVALYWPWSDARIFAPWRPIEVSPIGARFFSARGLEVLWSEAQWVVLPALSLGIVGALLRKLMRAPAATAPRRGRAGQESAGQEPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMS5</accession>
    <name>A0A0S2DMS5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_4570</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4570"/>
    <dbReference type="EnsemblBacteria" id="ALN59911">
        <property type="protein sequence ID" value="ALN59911"/>
        <property type="gene ID" value="GLE_4570"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4570"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4506"/>
    <dbReference type="OMA" id="TIAWAVY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="3">
        <location>
            <begin position="22"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="74"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="312" mass="33935" checksum="C27E90643939AAB0" modified="2016-02-17" version="1">MNNRSRPADVAAPLSWDDYRFLLAIGRAGSLNGAAKRLGVSHPTVFRRVNAIERALGVRLFERAREGYAPTPNGEEAIAAAAQIEERIAATERRLAGLDARPTGTVRLATVEPLLHRVLPPLLARFRRAHPGIVVQVTADNHTQDLSRHEADLALRPGGEPPEGLVGRKLARLASAVYRPRALRLPRGAGPQDLDGYDWLLPAGNLAHIAMAQWLRRMQYDRRAVFSANSLLGLREAAVAGLGLTVLPCYLGDGERGLVRVGDPVEAMGADLWLLQHPDLRRTERVRALAEALREGVRALQPDLSGRAGPIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMS7</accession>
    <name>A0A0S2DMS7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Bifunctional ligase/repressor BirA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Biotin operon repressor</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Biotin--[acetyl-CoA-carboxylase] ligase</fullName>
            <ecNumber evidence="3">6.3.4.15</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Biotin--protein ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Biotin-[acetyl-CoA carboxylase] synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">birA</name>
        <name evidence="5" type="ORF">GLE_4336</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>ATP + biotin + L-lysyl-[protein] = AMP + diphosphate + H(+) + N(6)-biotinyl-L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:11756"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.15"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the biotin--protein ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.15" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948972.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4336"/>
    <dbReference type="EnsemblBacteria" id="ALN59677">
        <property type="protein sequence ID" value="ALN59677"/>
        <property type="gene ID" value="GLE_4336"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4336"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4275"/>
    <dbReference type="OMA" id="AVWKHIE"/>
    <dbReference type="OrthoDB" id="1842956at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004077">
        <property type="term" value="F:biotin-[acetyl-CoA-carboxylase] ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00978">
        <property type="entry name" value="Bifunct_BirA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030855">
        <property type="entry name" value="Bifunct_BirA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004408">
        <property type="entry name" value="Biotin_CoA_COase_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003142">
        <property type="entry name" value="BPL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013196">
        <property type="entry name" value="HTH_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008988">
        <property type="entry name" value="Transcriptional_repressor_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02237">
        <property type="entry name" value="BPL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08279">
        <property type="entry name" value="HTH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50037">
        <property type="entry name" value="SSF50037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00121">
        <property type="entry name" value="birA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0092">Biotin</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="4">
        <location>
            <begin position="79"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="3">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Biotin binding" evidence="3">
        <location>
            <begin position="90"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Biotin binding" evidence="3">
        <location>
            <begin position="117"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="333" mass="34391" checksum="7652D1620F958EB8" modified="2016-02-17" version="1">MDDRALLQRLIAGPATGDALAAASGQTRAAVWKRIEALREAGVAIEAKPGRGYALSQPLDLLDAAAIEAALSAPARARLDSLDVAWSIDSTNSELLRRATPARGAAVLLAERQTGGRGRRGRVWASPLAAHLYLSLARAFGGGLARLGGLSLVAGIAAAQALHALGFAAVRLKWPNDLVALDGDGLRKLGGLLVEGGGEYAGPARAVIGLGLNVRMPAAAAQIDQPWCDLAGLAELAGARPPTRDAVVAALLDALLPALDEFDTQGLAPFLDRYAAYDALAGQAVGVLGSDREHRGVALGLADDGALRVRLDDGEERRFHAGEVSVRRGGATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMT3</accession>
    <name>A0A0S2DMT3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_20370</name>
        <name evidence="2" type="ORF">GLE_4154</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948830.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4154"/>
    <dbReference type="EnsemblBacteria" id="ALN59496">
        <property type="protein sequence ID" value="ALN59496"/>
        <property type="gene ID" value="GLE_4154"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4154"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4096"/>
    <dbReference type="OMA" id="WDCATGN"/>
    <dbReference type="OrthoDB" id="1687413at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="44"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="258" mass="28700" checksum="0A691DCA0B0CDC7D" modified="2016-02-17" version="1">MQRNDFKDHFSAIADTYATSRPEYPDALFDAIAAHVPAHSEVWEPGCGSGQATRGLAARWARVHASDPSAQQLQRHWAHAAAMRGEGNVRLSVAPGERCELDDGSLGLVAVAQALHWFERERFFAQCERVLAPGGVLAAWCYGDFEIPEGMDAAVSGFRADIDQYWQRENAEVREGYAGYGWPFEALPAPALWVSARWGLARFLGYLNSLSASERRKLATGEDPVYAHRSALSRAWGPPDSERELRWPLTLHLRRKPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN09</accession>
    <name>A0A0S2DN09_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4613</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4613"/>
    <dbReference type="EnsemblBacteria" id="ALN59954">
        <property type="protein sequence ID" value="ALN59954"/>
        <property type="gene ID" value="GLE_4613"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4613"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4548"/>
    <dbReference type="OMA" id="GWCLTHK"/>
    <dbReference type="OrthoDB" id="1785082at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="144"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="251" mass="27972" checksum="565A6AF1AAB7630A" modified="2016-02-17" version="1">MATALPALQPDPVRIDAELMQTLCDALADVVFFVKDEAGRYTHANLTLVRRLGLKRREEVIGRDVAEVFPARLAARYAQQDRRVLDGGTIENQLEVHLYPNRRPGWCLTGKRPLALPDGGRGLVGLSRDLGAPDGRDPTYERLRRVLEHMQAHYAGPLRIAALARLADLSVAQLERHFQRVFQLTPQQSLTRLRIEAAMRELCGDASIAEVGLACGFTDQSAFARQFKAMVGMAPRDYRALHRGGQWGPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN79</accession>
    <name>A0A0S2DN79_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4524</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4524"/>
    <dbReference type="EnsemblBacteria" id="ALN59865">
        <property type="protein sequence ID" value="ALN59865"/>
        <property type="gene ID" value="GLE_4524"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4524"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4460"/>
    <dbReference type="OMA" id="WIGGMKF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007339">
        <property type="entry name" value="RclC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40106">
        <property type="entry name" value="PTHR40106"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04224">
        <property type="entry name" value="DUF417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="300" mass="31620" checksum="3171F4F5452335BB" modified="2016-02-17" version="1">MHCAMQRAPMARVWEVSARVLGLWMLWFGAMRALDFEIAALAQFLNASGLAGLASQAAWLSPALGALECAIGAALLLAPAGRWRRGAALAAMAFWGAGLLGLLSPAAWIHQPPYDGFPVIGSGQTLLKHLGIAGLALGVFAHERGCARGGARALWTLWAGQMLVLVWIGLMKFTQVEAEGVAGLMRSSPLFSWLYGPLDVQGASNLIGAVELATAASIALWPWRPRLARWGLWAAVATYLLTNSFLFTLPGWQPDYGAPFVGGTGQFLLKDLLLLLGALALLRAGATERRGGSAGAAPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNF0</accession>
    <name>A0A0S2DNF0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60021">
        <property type="protein sequence ID" value="ALN60021"/>
        <property type="gene ID" value="GLE_4680"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4680"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4616"/>
    <dbReference type="OMA" id="QCNKKEI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="289" mass="33575" checksum="1C0E9AA56D1F3DE0" modified="2016-02-17" version="1">MRSDMYKVIVERPRTGAGWTKPGRQPREPDDRRACEGMRPRGRSRKWLNENLRPLQRWLERQAGRRWDAVYSELCKGVDRRNTVQQHIHEHLRDFVAVDVLEIGGRLCVARDWGGVVALADSRCDLYVDPRNGCLMRNEEAAADRARRRREHLLEVRARQAGWREGVRRLDDTAQLHRVDGIWYRVELAPVPPPRPSKRKPGACVPVPAFDALLRDKVGSCAGKRCGLYGRCDVYARSKRQLSQAELIAYRLRNGDGPDPFDPRWTATRRERTRKCRGPLYFGEQHKEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNI1</accession>
    <name>A0A0S2DNI1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GDSL-like Lipase/Acylhydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">SGNH/GDSL hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_23295</name>
        <name evidence="2" type="ORF">GLE_4789</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949317.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4789"/>
    <dbReference type="EnsemblBacteria" id="ALN60130">
        <property type="protein sequence ID" value="ALN60130"/>
        <property type="gene ID" value="GLE_4789"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4789"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4722"/>
    <dbReference type="OMA" id="IIATTGW"/>
    <dbReference type="OrthoDB" id="1247435at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH_hydro" evidence="1">
        <location>
            <begin position="7"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="204" mass="21889" checksum="AA6F368B4E9C8BF8" modified="2016-02-17" version="1">MAQSYLALGDSYSIGEAVPEAGRWPVQLAAGLRARGVELASPRIIATTGWTTDELALALDLAEPLGDWDFVSLLIGVNNQYRGRSAAQYAGEYRQLLERTIGYARGRPDRVLALSIPDWGATPFGARDKRGAATIGAELDVFNITAGEICARHGVAFVDIAPLSRELVAQPAMLADDGLHPSAQMYARWTELALPVAEGLLRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNJ5</accession>
    <name>A0A0S2DNJ5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4801</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ALN60142">
        <property type="protein sequence ID" value="ALN60142"/>
        <property type="gene ID" value="GLE_4801"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4801"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4733"/>
    <dbReference type="OMA" id="GHWWLNQ"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
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        <property type="match status" value="1"/>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <end position="287"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="316" mass="33932" checksum="39DD6ABE687CF47B" modified="2016-02-17" version="1">MLSRWDGDARADLKAVVVLRDGQLAAQRYYNGNDAQSLHDIRSAGKSVTALLAGIAADRGRLRFDQPAARCLPGAGQALAGARVSDLLSMRSGLDADDENPQSPGNEDRLDEAADPVAFALSAPRREPPGTRYAYNSLTAYLAGLCVEGATGQPLDAFADAHLFAPLGIAHWRWQRDAGGHAKGQGNLSLRAGDFARIGQMALDDGRWQGREIVRADTLRAILAPRARIGAVDPYADEYGYMWYRKRLRVGAGEVPVAFASGNGGNKLYLVPSLRMVVAIQSSAYGRGYGQRRSQDILRALLGAAPTRADGTEKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNK6</accession>
    <name>A0A0S2DNK6_LYSEN</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4791</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60132">
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        <property type="gene ID" value="GLE_4791"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4791"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4724"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="50" mass="5553" checksum="801AFBD83ADA4DE1" modified="2016-02-17" version="1">MGQDAPYGAAPRAFRAIVALDPKKIRPFLWLLSLWLQTKKVTRPLADGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNW9</accession>
    <name>A0A0S2DNW9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PepSY domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_23005</name>
        <name evidence="2" type="ORF">GLE_4732</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4732"/>
    <dbReference type="EnsemblBacteria" id="ALN60073">
        <property type="protein sequence ID" value="ALN60073"/>
        <property type="gene ID" value="GLE_4732"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4732"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4666"/>
    <dbReference type="OMA" id="GMAQVEQ"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="21"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="PepSY" evidence="1">
        <location>
            <begin position="103"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="160" mass="17390" checksum="C44EEA6AB9115CBE" modified="2016-02-17" version="1">MRSKPIPPRPVPPRLGGRILLALALAVAGAGLSAGAQVRENQTALTEHDVRNRLAERGYTRVNDLDFSGGVWRADARSADGNRVQVALDPTDGRIYPDEQVAQLSRRDIQASLSAAGYTDIHDLDYRDGLWLAKAEDPGGRDVELRLDPDNGRIVGVDKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP56</accession>
    <name>A0A0S2DP56_LYSEN</name>
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        <submittedName>
            <fullName evidence="4">Porin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_24380</name>
        <name evidence="3" type="ORF">GLE_5029</name>
    </gene>
    <organism evidence="3 5">
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        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW28318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_5029"/>
    <dbReference type="EnsemblBacteria" id="ALN60370">
        <property type="protein sequence ID" value="ALN60370"/>
        <property type="gene ID" value="GLE_5029"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5029"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4957"/>
    <dbReference type="OMA" id="LNQNWGL"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
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    <dbReference type="Pfam" id="PF13505">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726591" evidence="1">
        <location>
            <begin position="21"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="2">
        <location>
            <begin position="7"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="216" mass="23934" checksum="5BE6495050206569" modified="2016-02-17" version="1">MKRALLALTLAAALPFTASAAEGISYNYVEAGYAKFDAKNKFADSDGWTIAGSYAFHPNFHVFGSYSQQETDSKNLNIDGNVFRIPSTDVDRFNVGLGYNHELSSRVDLVTRIAYEQNKYDFDNALGGGSQKFKGGFVEAGVRGSLAPNWEGYAFAGYQDFDKAERYGDLTKQYDGKFYGRVGTQVKFNQSWGITADAKFVDGGHKEFFIGPRFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP84</accession>
    <name>A0A0S2DP84_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Binding-protein-dependent transport system inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BV903_12140</name>
        <name evidence="8" type="ORF">FE772_24160</name>
        <name evidence="6" type="ORF">GLE_4984</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">C3</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000029">
        <property type="protein sequence ID" value="OPD63667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949462.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000029.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4984"/>
    <dbReference type="EnsemblBacteria" id="ALN60325">
        <property type="protein sequence ID" value="ALN60325"/>
        <property type="gene ID" value="GLE_4984"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63667">
        <property type="protein sequence ID" value="OPD63667"/>
        <property type="gene ID" value="BV903_12140"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4984"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4911"/>
    <dbReference type="OMA" id="YYRVVRN"/>
    <dbReference type="OrthoDB" id="1734230at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="76"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="189"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="238"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="72"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN60325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD63667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW28278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="288" mass="30502" checksum="5618AA0A7D623E6E" modified="2016-02-17" version="1">MRFVTPLPPLARTCLTVLGLLAAACWLGPWLGRYGPVLPDWEALSAAPGTAGHWFGTDAIGRDVFARTLAGGRLSLGIGLLASVVALVIGLGYGAVAGLAGGWVERWMLRVLDVFSALPFLLVVILLLTLFDRSLWLLLAAIGGYVWIDLARVMRAEAARLREAAFVLAAQAAGASFGQRLRWHVLPNLLPLALVYLGLILPQAILVESFLGFLGLSIDEPSSSWGGLLAEGVQELDSAPWTLLFPAGFLVATLAAFQFLGDGLRDWLDVRGQAQARGDGPAPEAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPC3</accession>
    <name>A0A0S2DPC3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Trans-aconitate 2-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.144</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tam</name>
        <name evidence="2" type="ORF">FE772_24500</name>
        <name evidence="1" type="ORF">GLE_5055</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.144" evidence="1"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949520.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5055"/>
    <dbReference type="EnsemblBacteria" id="ALN60396">
        <property type="protein sequence ID" value="ALN60396"/>
        <property type="gene ID" value="GLE_5055"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5055"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4983"/>
    <dbReference type="OMA" id="YLAFADH"/>
    <dbReference type="OrthoDB" id="1739932at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030798">
        <property type="term" value="F:trans-aconitate 2-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023149">
        <property type="entry name" value="Trans_acon_MeTrfase_C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="255" mass="28374" checksum="206FE58E9F2257DD" modified="2016-02-17" version="1">MWDPAKYLDFADLRGRPFFDLTARIGAREPRRVVDLGCGPGNLTAALAQRWPQAALEASDNSPEMVAAARQAGLDAQLLDVRDWTPKPDTDVVISNAVLQWVPEHRELLQRWVRELPAGAWIAIQVPGNFDAPSHALTRRLAASAGWADTLGAIGLRDEGAVDAPTEYAERLARLGCQVDAWETSYTQRLHGENAVLEWITGTALRPIKAALSAHDWQHFRTELAAMLDEAYPPRSDGTTWFEFRRIFVVARTPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPI0</accession>
    <name>A0A0S2DPI0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Type III secretion apparatus protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">epaO</name>
        <name evidence="6" type="ORF">BV903_11145</name>
        <name evidence="5" type="ORF">GLE_5119</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">B25</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FliN/MopA/SpaO family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000026">
        <property type="protein sequence ID" value="OPD63857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949569.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5119"/>
    <dbReference type="EnsemblBacteria" id="ALN60460">
        <property type="protein sequence ID" value="ALN60460"/>
        <property type="gene ID" value="GLE_5119"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63857">
        <property type="protein sequence ID" value="OPD63857"/>
        <property type="gene ID" value="BV903_11145"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5119"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5044"/>
    <dbReference type="OrthoDB" id="816330at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030254">
        <property type="term" value="P:protein secretion by the type III secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001543">
        <property type="entry name" value="FliN-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036429">
        <property type="entry name" value="SpoA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003283">
        <property type="entry name" value="T3SS_OMP_SpaO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013385">
        <property type="entry name" value="T3SS_SpaO/YscQ/SpaO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01052">
        <property type="entry name" value="FliMN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01339">
        <property type="entry name" value="TYPE3OMOPROT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101801">
        <property type="entry name" value="SSF101801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02551">
        <property type="entry name" value="SpaO_YscQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="FliMN_C" evidence="4">
        <location>
            <begin position="299"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="269"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD63857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="367" mass="39705" checksum="FEF7AB6C64CEA117" modified="2016-02-17" version="1">MADTQADIGAPARAGEDLAARAQPLRGKVPALPLWQAQALCAFFGAPQRWPLREGGGWLEFFRAGPIDGETVTLEGDGARVRLQLDSGLALDADTGLHWSGYRGRSRVLAWSLAHESQLMKLSQALDVALIPVVDDGAASLRELQARGGEDDGLWLGFRILDGAGQARSRGHLRIPPGWVDRLLLRAEPFERARGDGDGEQYRDWSQLPVPVTLSWDGPSLRYAQWRQLRAGDVLVIGNYQRPPPVRALAPGLAWPLAPVADGWRIDGPPLTLSTHQETSAMSDPESAADAPEAATGPDVPVRLEFDLGRLECRYEDLAGFQPGYVFALPSRLEGANVVIRANGRDAGRGEIVAVGETLGVRLLSWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPI8</accession>
    <name>A0A0S2DPI8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4747</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60088">
        <property type="protein sequence ID" value="ALN60088"/>
        <property type="gene ID" value="GLE_4747"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4747"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4681"/>
    <dbReference type="OMA" id="SIPQIFW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010767">
        <property type="entry name" value="Phage_CGC-2007_Cje0229"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07087">
        <property type="entry name" value="DUF1353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="189" mass="20327" checksum="335FA021CF058B2E" modified="2016-02-17" version="1">MPDGDAEVVAEAAADYGRFVGLPAKIALDENGRSAELLEPIGYVATSGVEWPVPAGAWLDGASIPKAFWSVIGGPFEGKYREPSIVHDHYCIVKTQPWRDTHRMFHAAMLCRGVSGFKARVMYYAVYRFGPRWGVPGDIAEAAPAQAAEVADDANADSILRDVEAIRDGALSLHDIEQLADRSADSPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPS0</accession>
    <name>A0A0S2DPS0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_25355</name>
        <name evidence="2" type="ORF">GLE_5239</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60580">
        <property type="protein sequence ID" value="ALN60580"/>
        <property type="gene ID" value="GLE_5239"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5239"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5157"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="92" mass="10369" checksum="6638116D903AB680" modified="2016-02-17" version="1">MRIRAVLFLRAAMLQRKRRARRPHHRNCDETFAVTAMTRSRLAPLLQGLRPLAMQSIAVIPAKANRSDAAPPPHPEAAKPQTRHSGESRNPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ27</accession>
    <name>A0A0S2DQ27_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_24440</name>
        <name evidence="2" type="ORF">GLE_5042</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949510.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60383">
        <property type="protein sequence ID" value="ALN60383"/>
        <property type="gene ID" value="GLE_5042"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5042"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4970"/>
    <dbReference type="OMA" id="RASWIME"/>
    <dbReference type="OrthoDB" id="1732011at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242240" evidence="1">
        <location>
            <begin position="21"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="242" mass="27168" checksum="B3D23B1D666F80A4" modified="2016-02-17" version="1">MRPYALLLFALASLPHSAAAMTFMEANFVCPIDGQPFQTRVAASGTAFGRYFDGQHYGPIASPWPLPVCPGNGFVVFDRERRYGEAELARLREFVASAEYRGWVANDTPYYRLARQQAVLGESEDAIAQSLLVATWEAGPRRYPRYAEEALAAWQRRALREAGSGGYDTRMLVGELQRRLGRFDDARATFEALRADRGFPGKRLGAEEADYRRKIVEAQLALIRDRSVAHARLDENGEIVDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQK1</accession>
    <name>A0A0S2DQK1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Intermembrane phospholipid transport system permease protein MlaE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BV903_25005</name>
        <name evidence="13" type="ORF">FE772_25330</name>
        <name evidence="11" type="ORF">GLE_5234</name>
    </gene>
    <organism evidence="11 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">C3</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">B25</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell inner membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the MlaE permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000103">
        <property type="protein sequence ID" value="OPD61177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949653.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000103.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5234"/>
    <dbReference type="EnsemblBacteria" id="ALN60575">
        <property type="protein sequence ID" value="ALN60575"/>
        <property type="gene ID" value="GLE_5234"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61177">
        <property type="protein sequence ID" value="OPD61177"/>
        <property type="gene ID" value="BV903_25005"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5234"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5152"/>
    <dbReference type="OMA" id="NYLVFPK"/>
    <dbReference type="OrthoDB" id="1253502at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003453">
        <property type="entry name" value="ABC_MlaE_Proteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030802">
        <property type="entry name" value="Permease_MalE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30188">
        <property type="entry name" value="PTHR30188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02405">
        <property type="entry name" value="MlaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00056">
        <property type="entry name" value="TIGR00056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="138"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="224"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN60575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OPD61177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW28476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="249" mass="26474" checksum="1C443978501DBE87" modified="2016-02-17" version="1">MALFDVVRSLGRAGLFSLSVFRASKPTADFFRELIREIYKIGARSLPIIAVGGAFVGLSVTLLGYRALDTYGAANQVSAMLGLGLYRELGPVLTALLFIGRAGSSIAAELGLMRATDQITALGLMAIDPVGKAVAPRFWAAVLCVPLLTGFFCSLAISASYFESVHVIGLEPGIFWQVLKDSVDFFDDFLMAFVKSAVFGGTAALVAAYVGYHAEPTIEGTSVATTQAVVNASLLVLMFNFVMSAFLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQS9</accession>
    <name>A0A0S2DQS9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">dam</name>
        <name evidence="5" type="ORF">GLE_5512</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949854.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5512"/>
    <dbReference type="REBASE" id="132002">
        <property type="entry name" value="M.LenC3ORF5512P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60853">
        <property type="protein sequence ID" value="ALN60853"/>
        <property type="gene ID" value="GLE_5512"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5512"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5426"/>
    <dbReference type="OMA" id="GDWDKDK"/>
    <dbReference type="OrthoDB" id="1487464at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006306">
        <property type="term" value="P:DNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002941">
        <property type="entry name" value="DNA_methylase_N4/N6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015840">
        <property type="entry name" value="DNA_MeTrfase_ParB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB/Sulfiredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001091">
        <property type="entry name" value="RM_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01555">
        <property type="entry name" value="N6_N4_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02195">
        <property type="entry name" value="ParBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036758">
        <property type="entry name" value="Aden_M_ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00508">
        <property type="entry name" value="S21N4MTFRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00470">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ParB" evidence="4">
        <location>
            <begin position="6"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="422" mass="46780" checksum="0E7250292BC6FFA4" modified="2016-02-17" version="1">MTLQIEQRPIGALIPYARNARTHSDAQVAQIAASILEFGWTNPILVDGANGVIAGHGRLLAARQLGLDIVPVIELAHLTSAQKRAYILADNRLAENAGWDDELLALELAELRDAEFDLDLIGFSDEEIDELLGIGEDAGLTDEDAAPEPEPESVSKRGDVWICGNHRVVCGDATSADDYAALLGGELIDMTFTDPPYNVDYGNNPRDKIRGTQREILNDNLGTDFGSFLESACRNLLEVTKGAVYVAMSSSELDRLQVAFRAAGGRWSDFIIWAKNHFVMGRADYQRQYEAILYGWRDGNDRFWCGARDQGDVWFIDRPARSELHPTMKPVALVERAIRNSSKSRDLVLDPFGGSGTTMIACEKTGRRARLIELDPKYVDVIVRRWQSFSGKNALLCSSGQTFLQIESERCSSERHESTSLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA28</accession>
    <name>A0A0S2DA28_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0033</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0033"/>
    <dbReference type="EnsemblBacteria" id="ALN55392">
        <property type="protein sequence ID" value="ALN55392"/>
        <property type="gene ID" value="GLE_0033"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0033"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.40"/>
    <dbReference type="OMA" id="WHRPAAC"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="526" mass="58040" checksum="3F093C66743E2511" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAK6</accession>
    <name>A0A0S2DAK6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA-cytidine(32) 2-sulfurtransferase</fullName>
            <ecNumber evidence="6">2.8.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Two-thiocytidine biosynthesis protein A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA 2-thiocytidine biosynthesis protein TtcA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ttcA</name>
        <name evidence="9" type="ORF">GLE_0114</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>AH2 + ATP + cytidine(32) in tRNA + S-sulfanyl-L-cysteinyl-[cysteine desulfurase] = 2-thiocytidine(32) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[cysteine desulfurase]</text>
            <dbReference type="Rhea" id="RHEA:57048"/>
            <dbReference type="Rhea" id="RHEA-COMP:10288"/>
            <dbReference type="Rhea" id="RHEA-COMP:12157"/>
            <dbReference type="Rhea" id="RHEA-COMP:12158"/>
            <dbReference type="Rhea" id="RHEA-COMP:14821"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:141453"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">tRNA modification.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="6">The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TtcA family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.-" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0114"/>
    <dbReference type="EnsemblBacteria" id="ALN55473">
        <property type="protein sequence ID" value="ALN55473"/>
        <property type="gene ID" value="GLE_0114"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0114"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.117"/>
    <dbReference type="OMA" id="MNLDQKQ"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034227">
        <property type="term" value="P:tRNA thio-modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01850">
        <property type="entry name" value="TtcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012089">
        <property type="entry name" value="tRNA_Cyd_32_2_STrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="ATP_bind_3" evidence="8">
        <location>
            <begin position="64"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="PP-loop motif" evidence="6">
        <location>
            <begin position="70"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN55473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="315" mass="34836" checksum="B11D9C116B9DF76B" modified="2016-02-17" version="1">MFTDPWRRIGGLMSTVLPLAEPVRRARDAAAPAAPAAPERLGARLRHQVGRAIADFGMIEDGDKVMVCLSGGKDSYTLLDILLQLQKKAPVKFELVAVNLDQKQPDFPEHVLPQYLESIGVAYKILEQDTYSVVTRVVPEGKTMCSLCSRLRRGALYTYAAEQGFTKIALGHHRDDLVATFFLNLFFHAKLSGMPPKLLSDDGRHVVIRPLAYVREDDIVEYAAAKQFPIIPCNLCGSQENLQRKQVKRMMDAWERDTPGRLEIISRALGDIRPSQLSDPKLFDFLGLGQAGSAASKPPVWLDEAGSDDPVAQIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAN4</accession>
    <name>A0A0S2DAN4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0094</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55453">
        <property type="protein sequence ID" value="ALN55453"/>
        <property type="gene ID" value="GLE_0094"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0094"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="57" mass="6264" checksum="A3E83A15A804C274" modified="2016-02-17" version="1">MRMQARGVPRRAGEGAAESVWHAMPEGQKRRRRLSAPSIRTASGPGRSAWDRTMGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAP6</accession>
    <name>A0A0S2DAP6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945837.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0160"/>
    <dbReference type="EnsemblBacteria" id="ALN55519">
        <property type="protein sequence ID" value="ALN55519"/>
        <property type="gene ID" value="GLE_0160"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0160"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.162"/>
    <dbReference type="OrthoDB" id="2095346at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="115" mass="12532" checksum="8F08026B8A17DABC" modified="2016-02-17" version="1">MQSIDVLIAIIGGASACGVAAAVWLRRRRGSEPAAPGESPFEADPPWHEVLGVTADADRAEIEAAHRATRDAHVPERVAHLSARARRQAQWRLMQIDRAYAAAMRELGLGRDRSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAS7</accession>
    <name>A0A0S2DAS7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_02025</name>
        <name evidence="3" type="ORF">GLE_0239</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55598">
        <property type="protein sequence ID" value="ALN55598"/>
        <property type="gene ID" value="GLE_0239"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0239"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.241"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="92" mass="10361" checksum="52CE9FD511A9C976" modified="2016-02-17" version="1">MNWLRLLRPRGLFVKQAVSFFLVFSAVRFVAGVIDVRVSGARFERADPATTQAIRTTPRSAPRRRCGRNFSPDAFRSDGEGCSSDLGQERRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAY2</accession>
    <name>A0A0S2DAY2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA topoisomerase 1</fullName>
            <ecNumber evidence="8">5.6.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">DNA topoisomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">topA</name>
        <name evidence="12" type="ORF">FE772_02540</name>
        <name evidence="11" type="ORF">GLE_0349</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945971.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0349"/>
    <dbReference type="EnsemblBacteria" id="ALN55707">
        <property type="protein sequence ID" value="ALN55707"/>
        <property type="gene ID" value="GLE_0349"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0349"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.346"/>
    <dbReference type="OMA" id="PECKYTR"/>
    <dbReference type="OrthoDB" id="223233at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03363">
        <property type="entry name" value="TOPRIM_TopoIA_TopoI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00952">
        <property type="entry name" value="Topoisom_1_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023406">
        <property type="entry name" value="Topo_IA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005733">
        <property type="entry name" value="TopoI_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028612">
        <property type="entry name" value="Topoisom_1_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025589">
        <property type="entry name" value="Toprim_C_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034149">
        <property type="entry name" value="TOPRIM_TopoI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42785">
        <property type="entry name" value="PTHR42785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13368">
        <property type="entry name" value="Toprim_C_rpt"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="SSF56712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01051">
        <property type="entry name" value="topA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00396">
        <property type="entry name" value="TOPOISOMERASE_I_PROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="10">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with DNA" evidence="8">
        <location>
            <begin position="167"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="437"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="577"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="763"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="820"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="763"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="8">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="33"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN55707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW24717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="853" mass="94338" checksum="F9FB28A39AA2797D" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAZ2</accession>
    <name>A0A0S2DAZ2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lipid-binding SYLF domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BV903_05865</name>
        <name evidence="6" type="ORF">FE772_01520</name>
        <name evidence="4" type="ORF">GLE_0121</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">C3</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000010">
        <property type="protein sequence ID" value="OPD65007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945810.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0121"/>
    <dbReference type="EnsemblBacteria" id="ALN55480">
        <property type="protein sequence ID" value="ALN55480"/>
        <property type="gene ID" value="GLE_0121"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65007">
        <property type="protein sequence ID" value="OPD65007"/>
        <property type="gene ID" value="BV903_05865"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0121"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.124"/>
    <dbReference type="OMA" id="MKIPEQA"/>
    <dbReference type="OrthoDB" id="1355636at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007461">
        <property type="entry name" value="Ysc84_actin-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04366">
        <property type="entry name" value="Ysc84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594795" evidence="2">
        <location>
            <begin position="27"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="Ysc84" evidence="3">
        <location>
            <begin position="104"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN55480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD65007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW24548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="309" mass="31803" checksum="7416DAB169A09AFC" modified="2016-02-17" version="1">MSRPQSRLLSLSLALSLGLSATAAVAGPDEDQRARDAMRVLGDIQQIPESAIPDKLFDEARAIVVVPDTLKVGLVFGGRRGHGLVSVKNPDGTWSNPSFIKLTGGSVGFQAGVQSSDIVLVFRGARGLDSIVNGKLTLGGDASVAAGPVGRTAAAATDGQLKAEIWSWSRARGLFAGIALDGAVLSIDDAANQAVYGSGNTPRMIFEGRASGQPSNAVVDFRDRLEEASAAARAKRVAEDQRPELGTTVYPAPGVTVAPPAGAAPAQAAPAHQRLAPAQPAQPQPVQGQPAPFENIPAQPNPAKVEPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAZ4</accession>
    <name>A0A0S2DAZ4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="12">2-polyprenylphenol 6-hydroxylase</fullName>
            <ecNumber evidence="12">1.14.13.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ubiB</name>
        <name evidence="12" type="ORF">GLE_0206</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">C3</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; ubiquinone biosynthesis [regulation].</text>
    </comment>
    <dbReference type="EC" id="1.14.13.-" evidence="12"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0206"/>
    <dbReference type="EnsemblBacteria" id="ALN55565">
        <property type="protein sequence ID" value="ALN55565"/>
        <property type="gene ID" value="GLE_0206"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0206"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.208"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd13972">
        <property type="entry name" value="UbiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010232">
        <property type="entry name" value="UbiB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045308">
        <property type="entry name" value="UbiB_bact"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01982">
        <property type="entry name" value="UbiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="544"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="574"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1" evidence="11">
        <location>
            <begin position="128"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN55565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="600" mass="66877" checksum="78DDC32F972681B9" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAZ6</accession>
    <name>A0A0S2DAZ6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidoglycan-binding LysM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0354</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0354"/>
    <dbReference type="EnsemblBacteria" id="ALN55712">
        <property type="protein sequence ID" value="ALN55712"/>
        <property type="gene ID" value="GLE_0354"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0354"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.351"/>
    <dbReference type="OMA" id="PELWGMN"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="351" mass="39288" checksum="C97D514CBF0E279D" modified="2016-02-17" version="1">MVKRGDTLWDISARFLKKPWLWPEIWQANPQIKNPHLIYPGDVISLAYLDRVAQAQVQPGPRQEAAITGVPLSEIEPFLKNLRVVDKFEDLPYVVGLEEDRLRVTQGQVAYIKGLPEASPGTRYAVVRPTQRYTRLDRVACCDIMRAADLDFRGKRTVDFEAIWTDVVVPDKGRELLGYELMQISTGTLSRGAVSGMQASTLVIDDTGREIRVGDRLIPVEAQPYDLQFFPHPPKAQFDYGRAQVLAVADLIRNGGPRDVIALSVGARDGIDNGTVFSTWRVGSRAVDRVKVGPDRDETTVGKNSRVRLPDEFAGHAMVFRTFDKVSYALIMDGVRPTKVGFELKHPDSPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB23</accession>
    <name>A0A0S2DB23_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0386</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0386"/>
    <dbReference type="EnsemblBacteria" id="ALN55744">
        <property type="protein sequence ID" value="ALN55744"/>
        <property type="gene ID" value="GLE_0386"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0386"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.383"/>
    <dbReference type="OMA" id="KQWRSDA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="80" mass="8776" checksum="3CC7DB4EFD79F393" modified="2016-02-17" version="1">MLIATLVRQIVKQARSPDQEGVSSWLFIGQCAASLGFVVYSVLLDNWAFVVTNSCLLATAVVGQMLAWRSRRFRGEGKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB92</accession>
    <name>A0A0S2DB92_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55713">
        <property type="protein sequence ID" value="ALN55713"/>
        <property type="gene ID" value="GLE_0355"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0355"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.352"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="77" mass="8644" checksum="C0AB5D7DA102BABE" modified="2016-02-17" version="1">MVATQFRRDGVRGNSQQRSGENRANRFKHGGHLPDSPSRFALCGHPDYSPEVAQHYQALTGYGRPVMGVQCNENLRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBK6</accession>
    <name>A0A0S2DBK6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, AraC family</fullName>
        </submittedName>
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    <gene>
        <name evidence="4" type="ORF">GLE_0552</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 5">C3</strain>
        </source>
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        <property type="gene ID" value="GLE_0552"/>
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    <dbReference type="KEGG" id="lez:GLE_0552"/>
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        <property type="component" value="Chromosome"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:sequence-specific DNA binding"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="AraC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037923">
        <property type="entry name" value="HTH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02311">
        <property type="entry name" value="AraC_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="SSF51215"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-0804">Transcription</keyword>
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            <begin position="146"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN55910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="247" mass="26971" checksum="3BDAAA310E62A024" modified="2016-02-17" version="1">MQSIRCKAYAPASAMPAHRHDEPSLCLVVSGRYEETQRGRAVAHGPGHLLYCAAGEPHSQRFAGEGARKLLLRPAPAALEFLDARGALEPGRHVAAPRLAALARELAAELDARDDCAAMVVEGLVLELLGLFGRGGEERGRAAWLQRVRDYLHEHQAGELALEGVAREVGRHPTHVAREFKRAFGVSVGGYLREIRVQRAERLLDGERASLAQIAIACGFCDQAHMSRVFRALRGTTPAARRRARRG</sequence>
</entry>
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    <accession>A0A0S2DBZ8</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">C3</strain>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="38" mass="4400" checksum="054A3DC201ADD30B" modified="2016-02-17" version="1">MNRRAAVASRAPSLRVRPADARARRRCGESRHPPDFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC12</accession>
    <name>A0A0S2DC12_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0522</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946093.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0522"/>
    <dbReference type="EnsemblBacteria" id="ALN55880">
        <property type="protein sequence ID" value="ALN55880"/>
        <property type="gene ID" value="GLE_0522"/>
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    <dbReference type="PATRIC" id="fig|69.6.peg.517"/>
    <dbReference type="OMA" id="TKLGDEW"/>
    <dbReference type="OrthoDB" id="226396at2"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="DUF802"/>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="50"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="DUF802" evidence="2">
        <location>
            <begin position="330"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="DUF802" evidence="2">
        <location>
            <begin position="385"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="820" mass="86589" checksum="B8BC039A1DFCC9E3" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC78</accession>
    <name>A0A0S2DC78_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Oxacillin resistance-associated protein fmtc</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLE_0774</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0774"/>
    <dbReference type="EnsemblBacteria" id="ALN56132">
        <property type="protein sequence ID" value="ALN56132"/>
        <property type="gene ID" value="GLE_0774"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0774"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.763"/>
    <dbReference type="OMA" id="WEPRYMA"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050071">
        <property type="term" value="F:lysyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
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        <property type="entry name" value="LPG_synthase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09924">
        <property type="entry name" value="LPG_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="112"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="144"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="192"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="227"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="318"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="360"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="383"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="405"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="443"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="482"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="LPG_synthase_C" evidence="9">
        <location>
            <begin position="525"/>
            <end position="812"/>
        </location>
    </feature>
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        <location>
            <begin position="840"/>
            <end position="875"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN56132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="875" mass="94127" checksum="AA75181A180AEE8D" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCA9</accession>
    <name>A0A0S2DCA9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 13">2-isopropylmalate synthase</fullName>
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        </recommendedName>
        <alternativeName>
            <fullName evidence="11 13">Alpha-IPM synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12 13">Alpha-isopropylmalate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 15" type="primary">leuA</name>
        <name evidence="16" type="ORF">FE772_04765</name>
        <name evidence="15" type="ORF">GLE_0819</name>
    </gene>
    <organism evidence="15 17">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="15 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">C3</strain>
        </source>
    </reference>
    <reference evidence="16 18" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13">Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>3-methyl-2-oxobutanoate + acetyl-CoA + H2O = (2S)-2-isopropylmalate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21524"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 13">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.13" evidence="6 13"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946320.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0819"/>
    <dbReference type="EnsemblBacteria" id="ALN56177">
        <property type="protein sequence ID" value="ALN56177"/>
        <property type="gene ID" value="GLE_0819"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0819"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.808"/>
    <dbReference type="OMA" id="NTMRMLV"/>
    <dbReference type="OrthoDB" id="840579at2"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003852">
        <property type="term" value="F:2-isopropylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01025">
        <property type="entry name" value="LeuA_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013709">
        <property type="entry name" value="2-isopropylmalate_synth_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036230">
        <property type="entry name" value="LeuA_allosteric_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005671">
        <property type="entry name" value="LeuA_bact_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08502">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00917">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110921">
        <property type="entry name" value="SSF110921"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00973">
        <property type="entry name" value="leuA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00815">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00816">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 13" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8 13" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="14">
        <location>
            <begin position="22"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ALN56177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QCW25086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="538" mass="57400" checksum="378D773BB18F5AD4" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCN9</accession>
    <name>A0A0S2DCN9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Y1_Tnp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0949</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0949"/>
    <dbReference type="EnsemblBacteria" id="ALN56307">
        <property type="protein sequence ID" value="ALN56307"/>
        <property type="gene ID" value="GLE_0949"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0949"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.936"/>
    <dbReference type="OMA" id="HWDCVWL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01797">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="20"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="175" mass="19886" checksum="C69809307424072F" modified="2016-02-17" version="1">MNSPSDSPGYRALRRGRCSEQQRIYLVTTVCICRRRMFASDHVARVAADAIADPDKWLGAQLLCWVLMPDHWHGLIRFNSEVRLESVVASMKGRAARTVNRALNRKGFVWMPGFHDRALRTEEELLPAARYIVANPKRAGLVRRVGDYPYWDAIWTDRRASGLKALPQQPSGPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCQ6</accession>
    <name>A0A0S2DCQ6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase</fullName>
            <ecNumber evidence="10">2.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cobalamin-independent methionine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Methionine synthase, vitamin-B12 independent isozyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 13" type="primary">metE</name>
        <name evidence="13" type="ORF">GLE_0965</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = L-methionine + tetrahydropteroyltri-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:21196"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58140"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="ChEBI" id="CHEBI:58207"/>
            <dbReference type="EC" id="2.1.1.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (MetE route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the vitamin-B12 independent methionine synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.14" evidence="10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0965"/>
    <dbReference type="EnsemblBacteria" id="ALN56323">
        <property type="protein sequence ID" value="ALN56323"/>
        <property type="gene ID" value="GLE_0965"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0965"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.952"/>
    <dbReference type="OMA" id="KVMKGML"/>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00082"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003871">
        <property type="term" value="F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03311">
        <property type="entry name" value="CIMS_C_terminal_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00172">
        <property type="entry name" value="Meth_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013215">
        <property type="entry name" value="Cbl-indep_Met_Synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006276">
        <property type="entry name" value="Cobalamin-indep_Met_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002629">
        <property type="entry name" value="Met_Synth_C/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08267">
        <property type="entry name" value="Meth_synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01717">
        <property type="entry name" value="Meth_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000382">
        <property type="entry name" value="MeTrfase_B12_ind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="SSF51726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01371">
        <property type="entry name" value="met_syn_B12ind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 10" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="4 10 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 10 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Meth_synt_1" evidence="12">
        <location>
            <begin position="7"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="Meth_synt_2" evidence="11">
        <location>
            <begin position="429"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-methyltetrahydropteroyltri-L-glutamate binding" evidence="10">
        <location>
            <begin position="18"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="L-homocysteine binding" evidence="10">
        <location>
            <begin position="434"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="L-methionine binding" evidence="10">
        <location>
            <begin position="434"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-methyltetrahydropteroyltri-L-glutamate binding" evidence="10">
        <location>
            <begin position="518"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="697"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>5-methyltetrahydropteroyltri-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58207"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="487"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="564"/>
        </location>
        <ligand>
            <name>5-methyltetrahydropteroyltri-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58207"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="602"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="608"/>
        </location>
        <ligand>
            <name>5-methyltetrahydropteroyltri-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58207"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="644"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="646"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="668"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="729"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN56323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="761" mass="83606" checksum="894DD39E3A5DD663" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD27</accession>
    <name>A0A0S2DD27_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_05680</name>
        <name evidence="1" type="ORF">GLE_1017</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56375">
        <property type="protein sequence ID" value="ALN56375"/>
        <property type="gene ID" value="GLE_1017"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1017"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1005"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="311" mass="34856" checksum="7E8047F38504B9FE" modified="2016-02-17" version="1">MTTATDLTALLLDALGQRIDEPAAARLAQAMGVKPFKNATPNNSVHIGNRKLGLEVAATARIVNRAFFPPRKDGRRWVSWVSHAFVYPNYRGALPPGFDWSLDDAALAARFRRRVEGGLEEVRYALPSPREGLEAKATLDEDRDRPRHLLIRVAEESDYATIHPGGDPAHSVEDGFFAAWCALNDVLRADRLDADALAALRERRTTPLAFLSGPLGGLLWQGDVRPRHASFCHAYAKRLMAPDAACALFDARELFGDANYWRKPGEAMTEDNWENFDRIAPRYSQRLAQWRRGEIRSTVDRPQPDDDADRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD52</accession>
    <name>A0A0S2DD52_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_04105</name>
        <name evidence="3" type="ORF">FE772_06125</name>
        <name evidence="1" type="ORF">GLE_1117</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD65278.1"/>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946536.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000007.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56475">
        <property type="protein sequence ID" value="ALN56475"/>
        <property type="gene ID" value="GLE_1117"/>
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        <property type="gene ID" value="BV903_04105"/>
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    <dbReference type="OrthoDB" id="1659768at2"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD65278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="162" mass="18820" checksum="F954AD965CDBFFEA" modified="2016-02-17" version="1">MSRLRQWWLYLLSKRSEVAALDYKDAYMGKVIMDIHRLRSDKAQALVPLRALQPIHRIDRESALQATRARAEALAARREELLARGRLDLAALSEIIPSVSQIKVVADGARWLAFEGNGRLYAMREAFGEDCELLVEVEEYRFPKPHKIQRRLRRIRKLNALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD92</accession>
    <name>A0A0S2DD92_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">S-adenosylmethionine synthase</fullName>
            <shortName evidence="11">AdoMet synthase</shortName>
            <ecNumber evidence="11">2.5.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">MAT</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Methionine adenosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 17" type="primary">metK</name>
        <name evidence="18" type="ORF">BV903_03785</name>
        <name evidence="20" type="ORF">D9T17_21810</name>
        <name evidence="19" type="ORF">FE772_05795</name>
        <name evidence="17" type="ORF">GLE_1041</name>
    </gene>
    <organism evidence="17 21">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="17 21" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 21">C3</strain>
        </source>
    </reference>
    <reference evidence="18 22" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 22">B25</strain>
        </source>
    </reference>
    <reference evidence="20 23" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 23">OH11</strain>
        </source>
    </reference>
    <reference evidence="19 24" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 24">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + H2O + L-methionine = diphosphate + phosphate + S-adenosyl-L-methionine</text>
            <dbReference type="Rhea" id="RHEA:21080"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.5.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="11">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 2 divalent ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11 13">Belongs to the AdoMet synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.6" evidence="11"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000007">
        <property type="protein sequence ID" value="OPD65226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000055">
        <property type="protein sequence ID" value="ROU04762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946483.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000055.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1041"/>
    <dbReference type="EnsemblBacteria" id="ALN56399">
        <property type="protein sequence ID" value="ALN56399"/>
        <property type="gene ID" value="GLE_1041"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65226">
        <property type="protein sequence ID" value="OPD65226"/>
        <property type="gene ID" value="BV903_03785"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1041"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1029"/>
    <dbReference type="OMA" id="MPYLRPD"/>
    <dbReference type="OrthoDB" id="1024388at2"/>
    <dbReference type="UniPathway" id="UPA00315">
        <property type="reaction ID" value="UER00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004478">
        <property type="term" value="F:methionine adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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</entry>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Feng T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9 12">YC36</strain>
        </source>
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    </dbReference>
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            <end position="52"/>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
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        <source>
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    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="289" mass="29952" checksum="14A4BC9F8740D0D1" modified="2016-02-17" version="1">MTALDWGLLLIVALSALLGMARGLIGVAMSLAAWLLAGLGAFLFGGDVAHALGDSGLSWGSYAAGYTLCFAAIWIGVGILGYVIRTVAHSYGLSEMDRLMGLGLGTLRGLIFACALLVVLGMTTLPRERSWRDSSLAKVLMPGAQLMRSALPDPMAAKVDLEGRGGSLQETVQTEAGQLEKNIKGKMQLPTGGLDSLGGALPGAFGGQGPARGDPAQALPQPLPEPQAQRRGGGSGNPLTDMLPGALRDLMPKVPSGQGAGHRPRAGEDGRIQDDGRPIDSRNDDKHVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDW9</accession>
    <name>A0A0S2DDW9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nicotinate phosphoribosyltransferase</fullName>
            <ecNumber evidence="5 6">6.3.4.21</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Nicotinate phosphoribosyltransferase (NAPRTase) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pncB</name>
        <name evidence="6" type="ORF">FE772_07330</name>
        <name evidence="5" type="ORF">GLE_1383</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAPRTase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.21" evidence="5 6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946734.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1383"/>
    <dbReference type="EnsemblBacteria" id="ALN56740">
        <property type="protein sequence ID" value="ALN56740"/>
        <property type="gene ID" value="GLE_1383"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1383"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1365"/>
    <dbReference type="OMA" id="TFGFAMK"/>
    <dbReference type="OrthoDB" id="241792at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004516">
        <property type="term" value="F:nicotinate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01569">
        <property type="entry name" value="PBEF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041529">
        <property type="entry name" value="DUF5598"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041525">
        <property type="entry name" value="N/Namide_PRibTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016471">
        <property type="entry name" value="Nicotinamide_PRibTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43816">
        <property type="entry name" value="PTHR43816"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18127">
        <property type="entry name" value="NAMPT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04095">
        <property type="entry name" value="NAPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005943">
        <property type="entry name" value="NMPRT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="SSF51690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NAMPT_N" evidence="4">
        <location>
            <begin position="6"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="NAPRTase" evidence="3">
        <location>
            <begin position="172"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Nicotinamide ribonucleotide binding" evidence="2">
        <location>
            <begin position="293"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Nicotinamide ribonucleotide binding" evidence="2">
        <location>
            <begin position="334"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>beta-nicotinamide D-ribonucleotide</name>
            <dbReference type="ChEBI" id="CHEBI:14649"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="365"/>
        </location>
        <ligand>
            <name>beta-nicotinamide D-ribonucleotide</name>
            <dbReference type="ChEBI" id="CHEBI:14649"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="373"/>
        </location>
        <ligand>
            <name>beta-nicotinamide D-ribonucleotide</name>
            <dbReference type="ChEBI" id="CHEBI:14649"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR005943-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF18127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW25505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="474" mass="52797" checksum="EC6CA661071EDEC3" modified="2016-02-17" version="1">MQCLDNLLLNTDSYKASHWLQYPPGTDATFFYIESRGGVYDRTVFFGLQAILKEYLAKPVTHADIDEARDLFAAHGEPFNEAGWRYIVDKHDGLMPIRIRAVPEGTVVPTHQALVTIESTDPQAYWVPSYLETLLLRLWYPVTVATTSWHAKQTIRQFLERTSDDPEGQLPFKLHDFGARGVSSTESAALGGAAHLVNFLGTDTVSGLLLAKRYYHEPMAGYSIPAAEHSTITSWGREREVDAYRNMLDQFAKPGAIVAVVSDSYDIFHAIREHWGKTLREQVIASGATLVVRPDSGDPVDVVHQCLSLLDEAFGHTVNGKGYKVLNHVRVIQGDGINPTSIRAILERATSYGYATDNLAFGMGGALLQRLDRDTQKFALKCSAARVDGEWIDVYKDPVTDKGKSSKRGRMTLLRHREYGHFKTVPVPADAPSLEEATKPVGYEDAMVTVWEDGKLIADWTFAQVRERANAARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE23</accession>
    <name>A0A0S2DE23_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidylprolyl isomerase</fullName>
            <ecNumber evidence="1">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_07545</name>
        <name evidence="4" type="ORF">GLE_1431</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.2.1.8" evidence="1"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946770.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1431"/>
    <dbReference type="EnsemblBacteria" id="ALN56788">
        <property type="protein sequence ID" value="ALN56788"/>
        <property type="gene ID" value="GLE_1431"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1431"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1412"/>
    <dbReference type="OMA" id="RVQDNYV"/>
    <dbReference type="OrthoDB" id="1861282at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044665">
        <property type="entry name" value="E_coli_cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43246">
        <property type="entry name" value="PTHR43246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726724" description="Peptidylprolyl isomerase" evidence="2">
        <location>
            <begin position="26"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="3">
        <location>
            <begin position="66"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="311" mass="33448" checksum="D85E2D4146157B27" modified="2016-02-17" version="1">MTSIARTAPLALSLALAAATAAAAAATPAKPAAKGRTLQQILDASQPSDWRALDPRNTIYLELERGRAVIELAPQFAPEHVANIRALAHNGYWNGLSVNRSQDNYVVQWGDPEEDAAKRKPLGPGAKDKLPAEFARKSAGLKMTVLPDTDGWAKQAGFVDGFPAARDSATGSSWLAHCYGTVGAGRDMAADSSNGSELYVVIGQSPRHLDRNITTVGRVVQGMELLSVLPRGTGALGFYEKPSERAPIVSIALAADLPEAQRAKLEVLRTDTPLFAELVEARRNRRDDWYLQPAGHINLCNMPLPVREKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE25</accession>
    <name>A0A0S2DE25_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">UDP-N-acetylglucosamine 1-carboxyvinyltransferase</fullName>
            <ecNumber evidence="8">2.5.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Enoylpyruvate transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">UDP-N-acetylglucosamine enolpyruvyl transferase</fullName>
            <shortName evidence="8">EPT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">murA</name>
        <name evidence="11" type="ORF">BV903_16425</name>
        <name evidence="12" type="ORF">FE772_06515</name>
        <name evidence="10" type="ORF">GLE_1199</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">C3</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:18681"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:68483"/>
            <dbReference type="EC" id="2.5.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the EPSP synthase family. MurA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.7" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="1 8" id="KW-0132">Cell division</keyword>
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    <keyword evidence="2 8 10" id="KW-0808">Transferase</keyword>
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        <location>
            <begin position="6"/>
            <end position="407"/>
        </location>
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    <feature type="region of interest" description="Phosphoenolpyruvate binding" evidence="8">
        <location>
            <begin position="22"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-N-acetylglucosamine binding" evidence="8">
        <location>
            <begin position="121"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="92"/>
        </location>
        <ligand>
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        </ligand>
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        <location>
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        </location>
        <ligand>
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        <location>
            <position position="116"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
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    </evidence>
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    </evidence>
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            <dbReference type="EMBL" id="OPD62864.1"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
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    <sequence length="418" mass="43751" checksum="EE1CB24974BD373A" modified="2016-02-17" version="1">MQKIVVQGGQPLNGEVQISGAKNAVLPILCATLLADAPVTIRNVPRLHDVLTTAKLLGELGAGVSSEGASITVDPTTVNSHVAPYELVKTMRASVLVLGPLLAKYGQAEVSLPGGCAIGSRPVDQHIKGLQALGAEIVVENGYIKAHSNGRLKGARFVFDVVSVTGTENVLMAAALAEGTSVLENAAMEPEVVDLADCLNALGARIENAGSGRIVVHGVEKLHGGSHDVLPDRIETGTFLVAAAMTGGRVTVTGSRADTLDSVLDKLRDAGAKIDVDGDRITLDMGGRRARAVDLVTAPYPAFPTDMQAQFMALNCTAEGAGVINETIFENRFMHVNELLRLGADIRVDGHTAVVRGVAKLSGAPVMATDLRASACLILAGLVAQGETTIDRIYHLDRGYENIEQKLSGLGAKIRRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE61</accession>
    <name>A0A0S2DE61_LYSEN</name>
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        <submittedName>
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        </submittedName>
    </protein>
    <gene>
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            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="293" mass="31803" checksum="8B91762F23A1BDCA" modified="2016-02-17" version="1">MTPIQHRVQFDFEVEFTNGGGLQGQGFRLDIADAELAAYIVRDLRLLMAGPVRILNKTVLVEAHKRAAGALESGAVRYVDLSHTIEDGLVTYPGLPPAHICDYLSREASREVYAEGTQFQIGRIDMVANTGTYIDCPSHRYADGKDLSQIGPEDCADLDALVVRVPESLRAIDDSHFRGLELRGRAVLVHTGWDRHFATPAYGVGHPFLTEAAALWLRDCGVRLVGIDSVNIDDTSGKSRPVHSTLLGAGILIVEHLRNLAALPDAGFSFSAVPPKVKGMGTFPVRALAKLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DED5</accession>
    <name>A0A0S2DED5_LYSEN</name>
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        <submittedName>
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        </submittedName>
        <submittedName>
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        </submittedName>
        <submittedName>
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        </submittedName>
        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BV903_21435</name>
        <name evidence="9" type="ORF">D9T17_20480</name>
        <name evidence="8" type="ORF">FE772_07200</name>
        <name evidence="5" type="ORF">GLE_1355</name>
        <name evidence="6" type="ORF">LEN_3592</name>
        <name evidence="10" type="ORF">SAMN05421681_102274</name>
    </gene>
    <organism evidence="5 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 11">C3</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2016" name="DNA Res." volume="0" first="0" last="0">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer, Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M497-1</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="3">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">ATCC 29487</strain>
        </source>
    </reference>
    <reference evidence="6 14" key="4">
        <citation type="journal article" date="2017" name="DNA Res." volume="24" first="169" last="177">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
            <dbReference type="PubMed" id="28065880"/>
            <dbReference type="DOI" id=".1093/dnares/dsw055"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 14">M497-1</strain>
        </source>
    </reference>
    <reference evidence="7 13" key="5">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 13">B25</strain>
        </source>
    </reference>
    <reference evidence="9 15" key="6">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 15">OH11</strain>
        </source>
    </reference>
    <reference evidence="8 16" key="7">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 16">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bTHX family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP014940">
        <property type="protein sequence ID" value="BAV99079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000070">
        <property type="protein sequence ID" value="OPD61891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000048">
        <property type="protein sequence ID" value="ROU05197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNOG01000002">
        <property type="protein sequence ID" value="SDW58772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946712.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000048.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1355"/>
    <dbReference type="EnsemblBacteria" id="ALN56712">
        <property type="protein sequence ID" value="ALN56712"/>
        <property type="gene ID" value="GLE_1355"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAV99079">
        <property type="protein sequence ID" value="BAV99079"/>
        <property type="gene ID" value="LEN_3592"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61891">
        <property type="protein sequence ID" value="OPD61891"/>
        <property type="gene ID" value="BV903_21435"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDW58772">
        <property type="protein sequence ID" value="SDW58772"/>
        <property type="gene ID" value="SAMN05421681_102274"/>
    </dbReference>
    <dbReference type="KEGG" id="lem:LEN_3592"/>
    <dbReference type="KEGG" id="lez:GLE_1355"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1337"/>
    <dbReference type="OMA" id="YGNTRKR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000183696">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000218824">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030826">
        <property type="entry name" value="Ribo_THX"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04560">
        <property type="entry name" value="ribo_THX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAV99079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD61891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW25483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROU05197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDW58772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000183696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000218824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="61" mass="6220" checksum="3D6DA130914A5C89" modified="2016-02-17" version="1">MGKGDRKTAKGKRYNSSYGNARKAVTKATGSAAAPAAKKTAKTAVAKAPAKKVVAKKATKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEH9</accession>
    <name>A0A0S2DEH9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">LysR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_19240</name>
        <name evidence="5" type="ORF">FE772_07295</name>
        <name evidence="3" type="ORF">GLE_1376</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000055">
        <property type="protein sequence ID" value="OPD62277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946728.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000055.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1376"/>
    <dbReference type="EnsemblBacteria" id="ALN56733">
        <property type="protein sequence ID" value="ALN56733"/>
        <property type="gene ID" value="GLE_1376"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62277">
        <property type="protein sequence ID" value="OPD62277"/>
        <property type="gene ID" value="BV903_19240"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1376"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1358"/>
    <dbReference type="OMA" id="WALNDEQ"/>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="10"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD62277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="313" mass="34364" checksum="776D42D75F2A89AA" modified="2016-02-17" version="1">MAVNDRLLGIVAFVQSAEAGSFAVAADRLGVTRSAIGKRIARLEQQLGVRLFHRSTRRQSLSEDGQAYYERCVKALAELDAAEAALDSGRREPSGRLRISAPVMFGRHCVAPVVLELSRRHPKLEIDLSFNDRMVDLVEEGYDLGIRVGRLRDSATLAARLLTQEHLGICAAPAYLAKRGLPREIDDFAGHDAVIYGRHGQLVPWRLRDGDGEVREPQVNARLRFDDLQAIADAAIAGAGLAQLPCWLLSRYLRSGELQMVMHADRVVGSRISAVWPHTHYLPLRTRAAIDLLVERIPGMVGTGFGKPLAAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEJ6</accession>
    <name>A0A0S2DEJ6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 8">Glucans biosynthesis glucosyltransferase H</fullName>
            <ecNumber evidence="8">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">opgH</name>
        <name evidence="10" type="ORF">GLE_1640</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Glycan metabolism; osmoregulated periplasmic glucan (OPG) biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the glycosyltransferase 2 family. OpgH subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1640"/>
    <dbReference type="EnsemblBacteria" id="ALN56997">
        <property type="protein sequence ID" value="ALN56997"/>
        <property type="gene ID" value="GLE_1640"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1640"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1619"/>
    <dbReference type="OMA" id="TAGLHYW"/>
    <dbReference type="UniPathway" id="UPA00637"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009250">
        <property type="term" value="P:glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01072">
        <property type="entry name" value="MdoH_OpgH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023725">
        <property type="entry name" value="Glucans_biosynth_gluTrFase_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13632">
        <property type="entry name" value="Glyco_trans_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="92"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="409"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="464"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="499"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="555"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="582"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="9">
        <location>
            <begin position="238"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN56997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="649" mass="71541" checksum="0881237AF557BC87" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEV7</accession>
    <name>A0A0S2DEV7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dipeptidase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Renal dipeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_08020</name>
        <name evidence="2" type="ORF">GLE_1531</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1531"/>
    <dbReference type="EnsemblBacteria" id="ALN56888">
        <property type="protein sequence ID" value="ALN56888"/>
        <property type="gene ID" value="GLE_1531"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1531"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1513"/>
    <dbReference type="OMA" id="CDHPRNI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008257">
        <property type="entry name" value="Pept_M19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443">
        <property type="entry name" value="PTHR10443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01244">
        <property type="entry name" value="Peptidase_M19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51365">
        <property type="entry name" value="RENAL_DIPEPTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242557" evidence="1">
        <location>
            <begin position="30"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="385" mass="42227" checksum="FE97155184C2BE4D" modified="2016-02-17" version="1">MTPAPVRLSRRRLLQASAAVAALALPLHAAAAAAPPRPTHEQLKGYSPRVRAIVERALVIDMLAPLRLDMREDVYAQELDPRRIADFRLSGIDVFHNSWGLTGADARERVAEYLAGWHGLLARNSDLFVLVGRAADLDRAKREGKIAVISGVQNAEHFRKVEDVRFFHGLGLRCAQLTYNSQTTIGSGSTEREDGGLSDYGVAIVAEMEKVGMLVDVSHCGDRTTLDAIELARGPIAITHSNCRALNDHPRLKSDEAIRKLAAKGGVMGITGVRMFVGAKEPTTLDSMIDHIDHVARLVGIEHVGIGSDADLYGYDAMPADQLKALKASYKASYGFRERIDIEGFDRPTKIYELTQALLRRGYGESDIEAVLGGNFRRLLGQVWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF38</accession>
    <name>A0A0S2DF38_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cyclase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_09220</name>
        <name evidence="2" type="ORF">GLE_1795</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947053.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1795"/>
    <dbReference type="EnsemblBacteria" id="ALN57148">
        <property type="protein sequence ID" value="ALN57148"/>
        <property type="gene ID" value="GLE_1795"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1795"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1767"/>
    <dbReference type="OMA" id="WPCQNTD"/>
    <dbReference type="OrthoDB" id="831439at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="SSF102198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726645" evidence="1">
        <location>
            <begin position="23"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="326" mass="35583" checksum="7F7EA8DD6F1AD30E" modified="2016-02-17" version="1">MNVPRSLAAVALALALSPLASASAAEVGRSPWGADDQIGRLNLITEQSRAAVLGRLRGGKVYDLATEYFIGMPSWQAAGDPHYQFWMTHTPRGTRVDDPMQVGAAMNAHTSYTGSAFSMYSHTGTHIDALNHFGIGGRIWNGFEADRHLGDRGWNKAGIEKFPPLVARGVMLDIAAAKGVDMLPDQYRITRQDLREALDKQKTQLQRGDIVLIRTGRMKLFERADAYIAQPPGLGIDAARYLVEEAGAMVLGADNLSLETFPSEVQGEYVPLHTYLLAQHGVPIIELIALDELSRDRVYEFAFIGGPLKIRGGDAAPLRPIAIPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFN6</accession>
    <name>A0A0S2DFN6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Choloylglycine hydrolase</fullName>
            <ecNumber evidence="4">3.5.1.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">cbh</name>
        <name evidence="4" type="ORF">GLE_2049</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C59 family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.24" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947243.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2049"/>
    <dbReference type="EnsemblBacteria" id="ALN57399">
        <property type="protein sequence ID" value="ALN57399"/>
        <property type="gene ID" value="GLE_2049"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2049"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2014"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045302">
        <property type="term" value="F:choloylglycine hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029132">
        <property type="entry name" value="CBAH/NAAA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02275">
        <property type="entry name" value="CBAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBAH" evidence="3">
        <location>
            <begin position="21"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="376" mass="40380" checksum="3CBFF6ED891008A3" modified="2016-02-17" version="1">MCTNFLLSVPNVPSGSPGALQHITARCMELTGTLATRLYRVPAQQKFPIFRDHSQPWTGQYGFVALADPETMPEFTTFIDGINQAGLSCAALWLPGTQYATKADSGEQPVAFHDFVAWVMSQFDSVPTLVSALANVRIVGPQPDAPTYLPVHFIATDSQGLSAVIECIGGQTIVYGPDYRNGATNDAVLTNAPTYDWHRSNLEIYEKLSVVGSGTSRKADSGPPVGAGTVGLPGDITSPSRFIKAWFLRKGLGLLPRDGKGWLPTAKLDGATDSTQTVVNVALQLVQIVQATPYGTALVSSDKHPLPQQGDWTMWQVARDHTNAVYYFNSAFNATVQRVDLSQLDFGGGSVSAGKLASVQVMPAPGPWYNDLSAQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFS5</accession>
    <name>A0A0S2DFS5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2113</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57463">
        <property type="protein sequence ID" value="ALN57463"/>
        <property type="gene ID" value="GLE_2113"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2113"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2077"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="77" mass="8535" checksum="E7562A3E9DAE13EE" modified="2016-02-17" version="1">MTMLNVENLDAKHASGLRTSTQSAHDALVTAGVVIYSRPRSVRHPIFNREAASDYHPDAFPGGPRLGRRRLIINIIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG11</accession>
    <name>A0A0S2DG11_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">MarR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_11125</name>
        <name evidence="3" type="ORF">GLE_2208</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2208"/>
    <dbReference type="EnsemblBacteria" id="ALN57557">
        <property type="protein sequence ID" value="ALN57557"/>
        <property type="gene ID" value="GLE_2208"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2208"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2170"/>
    <dbReference type="OMA" id="WGVNRSV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="2">
        <location>
            <begin position="26"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="246" mass="27369" checksum="870D086A54F7AADD" modified="2016-02-17" version="1">MSLSPLQERFILHWGEMGSRWGVNRTVAQIHALLFLSERAITADEICETLNLARSNVSTSLRELQAWNLARVSHVLGDRRDHFETCKDVWDIFRAVVQERRRREIEPTLSMLRTAVLDGDNAAVAPDPADPRDRLTLARMREVLEFMETGTSWIDEMNRLDPKTLIKLLKMGARIQQFVRGPVKPLPEPQARAAGVLFADEAGEGDAIGHDALKHDAPERDAPEHDPGKTDAGEGDAAAPPGARSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG37</accession>
    <name>A0A0S2DG37_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57341">
        <property type="protein sequence ID" value="ALN57341"/>
        <property type="gene ID" value="GLE_1991"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1991"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1958"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="184" mass="19674" checksum="E02B6E028AD19EC8" modified="2016-02-17" version="1">MQAVAALFASEKGGDWDAYSSLSEVNWTDPTPQETIKGRYSRSGRILLKGFSIKDIPNGRPGTEYATAKKNEGESTISISGSLSGVESVSISKPFYSDDYLGILKTQFGASNVSVIANKCPAPDYQEGAGDGAFFEATLADKRQVFIQASQQDGGKYTGGFTVFDLARTRPSEAIAAMNCSQIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG46</accession>
    <name>A0A0S2DG46_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2256</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57605">
        <property type="protein sequence ID" value="ALN57605"/>
        <property type="gene ID" value="GLE_2256"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2256"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2221"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="78" mass="8730" checksum="6D92208682BE9269" modified="2016-02-17" version="1">MPPCCASAAMAGQLPLRQPALRACLRLSLADAERNFRVCWPGMCALRVHSRRTASCHSWIAKYCAPVSRLPMGFRKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH78</accession>
    <name>A0A0S2DH78_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Endonuclease</fullName>
            <ecNumber evidence="6">3.1.30.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BV903_02250</name>
        <name evidence="12" type="ORF">FE772_11980</name>
        <name evidence="10" type="ORF">GLE_2393</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">C3</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DNA/RNA non-specific endonuclease family.</text>
    </comment>
    <dbReference type="EC" id="3.1.30.-" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000004">
        <property type="protein sequence ID" value="OPD65605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947507.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2393"/>
    <dbReference type="EnsemblBacteria" id="ALN57742">
        <property type="protein sequence ID" value="ALN57742"/>
        <property type="gene ID" value="GLE_2393"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65605">
        <property type="protein sequence ID" value="OPD65605"/>
        <property type="gene ID" value="BV903_02250"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2393"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2355"/>
    <dbReference type="OMA" id="HGPLWSA"/>
    <dbReference type="OrthoDB" id="1438016at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018524">
        <property type="entry name" value="DNA/RNA_endonuclease_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001604">
        <property type="entry name" value="DNA/RNA_non-sp_Endonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044929">
        <property type="entry name" value="DNA/RNA_non-sp_Endonuclease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020821">
        <property type="entry name" value="Extracellular_endonuc_su_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040255">
        <property type="entry name" value="Non-specific_endonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13966">
        <property type="entry name" value="PTHR13966"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01223">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00892">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00477">
        <property type="entry name" value="NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="SSF54060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01070">
        <property type="entry name" value="NUCLEASE_NON_SPEC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 10" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595177" description="Endonuclease" evidence="7">
        <location>
            <begin position="23"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="Endonuclease_NS" evidence="9">
        <location>
            <begin position="54"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="NUC" evidence="8">
        <location>
            <begin position="55"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN57742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OPD65605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW26282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="257" mass="27445" checksum="4329A46E4F6DABED" modified="2016-02-17" version="1">MPPVARLATALVLALAAPAALAATCTSAHNDQYPSGRKPVLSNADLNEQTVSICYQDYNLYASKVTGTNLWSAQHLTRAKVIGAESISRIDSSFFSEPGFPTKHASYTNSGYDRGHMMPAGDASTTPAQKETFSVANIVPQTGKLNRGSWAKIENIVRTVAKEWDAAYVVTGPDFDNMNTTIASGAVVVPTQTWKAVYVPSAGVAGAYWCVNSTAPTCSLISLNELKRRAFVDPFPSLGTALRAQTASDWTDILVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH94</accession>
    <name>A0A0S2DH94_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein MgtC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FE772_12080</name>
        <name evidence="9" type="ORF">GLE_2414</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MgtC/SapB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2414"/>
    <dbReference type="EnsemblBacteria" id="ALN57763">
        <property type="protein sequence ID" value="ALN57763"/>
        <property type="gene ID" value="GLE_2414"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2414"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2376"/>
    <dbReference type="OMA" id="AANLWLT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003416">
        <property type="entry name" value="MgtC/SapB/SrpB/YhiD_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33778">
        <property type="entry name" value="PTHR33778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02308">
        <property type="entry name" value="MgtC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01837">
        <property type="entry name" value="MGTCSAPBPROT"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="150"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN57763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW26296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="179" mass="18757" checksum="B536A6E5AFEC36D3" modified="2016-02-17" version="1">MDWSEQLWVVGGAAYAMLLGGAIGFERELKNRPAGFRTHMLVAGASSLLIGMGLLALNDPRFRMPFLINMDPMRLVEAVIAGVSFIGAGTIFAWRGGRDIAGITTAASLLMAAVIGACAGLRYHVLALAATALTLLVLVALKRAERGLGLKPKAESESESKAGSESRSGAGPDSTSDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHD8</accession>
    <name>A0A0S2DHD8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_13185</name>
        <name evidence="7" type="ORF">GLE_2630</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947689.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2630"/>
    <dbReference type="EnsemblBacteria" id="ALN57978">
        <property type="protein sequence ID" value="ALN57978"/>
        <property type="gene ID" value="GLE_2630"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2630"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2589"/>
    <dbReference type="OMA" id="NASPKTH"/>
    <dbReference type="OrthoDB" id="943486at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="72"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="169"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW26476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="254" mass="26121" checksum="ED935FFDF10E91F0" modified="2016-02-17" version="1">MNAFLRTGLWLGGAVLAAGAAGAAALWSGIYDVGADAPHTRPVYAVLEYARERSVATRASAIAVPADLDDAERVRRGAGNYAAMCAGCHLTPGAGPSELSRGLYPAPPNLSQREVDAASAFWTIKHGIKASGMPAWGGSMDDAHLWDLVAFLGRLPSLDAQGYRELVARSDGHSHGGGEDASGHGAMGGHAHRNDARSGAGDAQGHDAGAGDAATGGHAHAHDDAHQPAPRDNAKAAPPTEDAHTHRDGRSHRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHJ4</accession>
    <name>A0A0S2DHJ4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947607.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57874">
        <property type="protein sequence ID" value="ALN57874"/>
        <property type="gene ID" value="GLE_2525"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2525"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2487"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="3"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="330" mass="36462" checksum="1B87B08CA40D9AC9" modified="2016-02-17" version="1">MSLRIGVLGAAEISPLAIFRAVAALPGAELVAIGSRRPGAAQAQARLHGLACACLDDQELLARRDIDWVYVPAANTDHYRDCEAALRTGKHVLVEKPATLSARELQALIALATTHGLSLVEAIMTRHHPWQAWLAEQVRARTWGRLLRHSTRLRHGLREGDRFRLRPGGGVLWDDGVYWLQAAQAVAGIDLGACAIEQAQADAVDVPTRVRIELTAPDGMKTDLEAEFALPRQAEHAFEFERARVVLGDFFRARIGRHKIHLDIAHASGERERVSFDEQNYYLNQLAYLAGDARDEDWPAQAQRSVERIAMLEALHGRLRPTLDGPSADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHJ8</accession>
    <name>A0A0S2DHJ8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nucleoprotein/polynucleotide-associated enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2701</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947748.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2701"/>
    <dbReference type="EnsemblBacteria" id="ALN58049">
        <property type="protein sequence ID" value="ALN58049"/>
        <property type="gene ID" value="GLE_2701"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2701"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2660"/>
    <dbReference type="OMA" id="ARAHGNG"/>
    <dbReference type="OrthoDB" id="1467864at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018636">
        <property type="entry name" value="DUF2058"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09831">
        <property type="entry name" value="DUF2058"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0543">Viral nucleoprotein</keyword>
    <keyword evidence="3" id="KW-0946">Virion</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="135"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="260" mass="27620" checksum="5C4251877123924B" modified="2016-02-17" version="1">MSDSLRDQLLGLGFKPAPKPERHERKGEDRRGGKPGAGGKPHGGKPQARADGGARGDGRPGGSTSGNHKPGGQERSGARPGQGRPGGKPGEAGAGRAGAKPGERGRGGRPGQGGRAATREDIDLAKAYAIRAQREKDERIAAEQAKQEEARLRREARARLAELLKDQALNVADADIARHFPYGGKIKRVYVTAEQLKQLNAGELGVLQQEGRYLLVTAAMLAQAEEIFPPAVALKVDPNAPADEDPYADPMYQVPDDLVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHM0</accession>
    <name>A0A0S2DHM0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Isochorismate synthase</fullName>
            <ecNumber evidence="3">5.4.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">menF</name>
        <name evidence="7" type="ORF">GLE_2624</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>chorismate = isochorismate</text>
            <dbReference type="Rhea" id="RHEA:18985"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29780"/>
            <dbReference type="EC" id="5.4.4.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the isochorismate synthase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.4.2" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2624"/>
    <dbReference type="EnsemblBacteria" id="ALN57972">
        <property type="protein sequence ID" value="ALN57972"/>
        <property type="gene ID" value="GLE_2624"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2624"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2583"/>
    <dbReference type="OMA" id="IVIRAIC"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008909">
        <property type="term" value="F:isochorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004561">
        <property type="entry name" value="IsoChor_synthase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00543">
        <property type="entry name" value="isochor_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chorismate_bind" evidence="6">
        <location>
            <begin position="160"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="436" mass="45847" checksum="102E39D8FFDDD9BE" modified="2016-02-17" version="1">MSEEAQLAPLAPVPASESNAGESTAGESGIGGFDASASSHEPAETSAAPALLSSYRAHDSLFSSSHTQLHARGVLQPLTRASDDDLAGASERLLAQVAAEAGRLPLLGAVPFEGGQPARLWVPAQAAFAAGRARHRGAVHGEARHADRIEPNVQPVPAPAQFKRNVERSLQRIHDGGLRKVVMSRSLRIDARVEVAQLLAQLLARAPSAYTFAMDLAGAGGPAACLIGSSPELLLSKRGARIVSNPLAGSIPRSADPHEDRRRAEGLLQSAKDLHEHALVIEDVAAALRPFCRELQVPAAPSLLATPTMWHLSTRVDGVLRDPTTSSLRLALALHPTPAVCGYPTEPARRTIRELEGYDRGLFTGLVGWCDSEGDGEWAVTIRCALVEEHRATVFAGAGIVAGSQPEAELAETTAKLRTMLGAMGLAHVAEAEGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHS6</accession>
    <name>A0A0S2DHS6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2839</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947850.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2839"/>
    <dbReference type="EnsemblBacteria" id="ALN58187">
        <property type="protein sequence ID" value="ALN58187"/>
        <property type="gene ID" value="GLE_2839"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2839"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2797"/>
    <dbReference type="OMA" id="HYIVLRP"/>
    <dbReference type="OrthoDB" id="1574819at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="186" mass="19154" checksum="2CC8BF7FB2FB7E24" modified="2016-02-17" version="1">MSPAPGAQPLEFGGHILLLSGPPGAGKTTLARALAAMPGSAKAHLHGDDFWRALGHGAIAPYRPEAHAQNAAVIDALAAAAQGYAGGGLFVVVDGVIGPWFLAPFRRLAAPVHYLVLQPPLQAAIERCGARGHGLSDAQTIAALHRQLSELGRWQPHALPTGEAGADDLLQSILRILAAGAHRLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHT6</accession>
    <name>A0A0S2DHT6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">PspC domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Stress-responsive transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BV903_06420</name>
        <name evidence="11" type="ORF">D9T17_16315</name>
        <name evidence="10" type="ORF">FE772_14255</name>
        <name evidence="8" type="ORF">GLE_2855</name>
    </gene>
    <organism evidence="8 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 12">C3</strain>
        </source>
    </reference>
    <reference evidence="9 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">OH11</strain>
        </source>
    </reference>
    <reference evidence="10 15" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 15">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000011">
        <property type="protein sequence ID" value="OPD64832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000041">
        <property type="protein sequence ID" value="ROU05756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947864.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2855"/>
    <dbReference type="EnsemblBacteria" id="ALN58203">
        <property type="protein sequence ID" value="ALN58203"/>
        <property type="gene ID" value="GLE_2855"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64832">
        <property type="protein sequence ID" value="OPD64832"/>
        <property type="gene ID" value="BV903_06420"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2855"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2817"/>
    <dbReference type="OMA" id="GPQFLIY"/>
    <dbReference type="OrthoDB" id="2022704at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007168">
        <property type="entry name" value="Phageshock_PspC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04024">
        <property type="entry name" value="PspC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="PspC" evidence="7">
        <location>
            <begin position="7"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD64832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW26646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROU05756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="67" mass="7324" checksum="3BC774D92B120F25" modified="2016-02-17" version="1">MSSATRSLCRSRHDRMLAGVCGGLALRLRWNPVLVRAGFVVLALATFVLPVALAYLVLWLLIPEEGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHV8</accession>
    <name>A0A0S2DHV8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-binding response regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_2633</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2633"/>
    <dbReference type="EnsemblBacteria" id="ALN57981">
        <property type="protein sequence ID" value="ALN57981"/>
        <property type="gene ID" value="GLE_2633"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2633"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2592"/>
    <dbReference type="OMA" id="VSGMTIK"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="19"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="160"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="228" mass="24078" checksum="8329A85232A13C9A" modified="2016-02-17" version="1">MNDMPDATDMPDFPREPLRIALSDDHPVVRAGVRALLDAGGGDAWTVVAEAAGADELLGLLAVTPLDLLITDFSMPGSRAGDGLTLLGLIRRRYPQLPVIVLTMIGNPPMLRSIADTGVAGLLDKAAAANELAQAVSAVAQGQHYYGRALSAALDPAAALARAGQALSPREAEVLRLFVAGFGVSQIAAQLHRSKQTISRQKTDAMAKLGLRNDREIYEYARSEGLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI09</accession>
    <name>A0A0S2DI09_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="12">TonB family C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLE_2979</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TonB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947954.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2979"/>
    <dbReference type="EnsemblBacteria" id="ALN58327">
        <property type="protein sequence ID" value="ALN58327"/>
        <property type="gene ID" value="GLE_2979"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2979"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2940"/>
    <dbReference type="OMA" id="FHPAQRN"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_C" evidence="11">
        <location>
            <begin position="143"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="52"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="64"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN58327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="222" mass="22971" checksum="F148FEFDBCD79E79" modified="2016-02-17" version="1">MSTPSPAPRRSLNLAAWLPSGKAWLWVAGAFAIGLALFAWVWQSNRGSGDGFYRAQGTPPTSEQPFYAPLPAPAPADGSAAPAPAPQQQLPEAAQSGGDERPQLVENPSPPPPPQASPSAPAPAPAAPTGAYVAAAPLSANRAPQYPPASLRRGEGGTVRVQVRVNEQGEVDDAEVVQGSGVRALDRAAVSAVRAWRFRPATRGGRPAADTVIVPITFNPNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI75</accession>
    <name>A0A0S2DI75_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Agmatine deiminase</fullName>
            <ecNumber evidence="2">3.5.3.12</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Agmatine deiminase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">aguA</name>
        <name evidence="3" type="ORF">FE772_14610</name>
        <name evidence="2" type="ORF">GLE_2929</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.3.12" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947919.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2929"/>
    <dbReference type="EnsemblBacteria" id="ALN58277">
        <property type="protein sequence ID" value="ALN58277"/>
        <property type="gene ID" value="GLE_2929"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2929"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2891"/>
    <dbReference type="OMA" id="WCRDHGP"/>
    <dbReference type="OrthoDB" id="771174at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047632">
        <property type="term" value="F:agmatine deiminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004668">
        <property type="term" value="F:protein-arginine deiminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009446">
        <property type="term" value="P:putrescine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007466">
        <property type="entry name" value="Peptidyl-Arg-deiminase_porph"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31377">
        <property type="entry name" value="PTHR31377"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04371">
        <property type="entry name" value="PAD_porph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="345" mass="38440" checksum="6574089153A6B038" modified="2016-02-17" version="1">MTNNALRFPAEWEPQSAVLIAWPNADTDWADRLGEVEETYIALVAAITRFQPALICVADDDVQAYARARLSSARIDMSRVRFIDAPYDDTWLRDSGPITLKREDGGFRLLDFRFTGWGGKFDASQDDLLVERLHEQGVFADSERESIDFALEGGGIETDGAGTLLTTWRCLHERHPTLSRDEITAKLSAWLRQERVLWLDHGYLEGDDTDAHIDTLARFAAVDAIVYQGCDDPSDSHYAELQAMGAELATLRTRDGQPYRLFELPWAQPIIDEDRRLAASYANFLIVDGAVLMPAYGDAADAAAQAVLAQAFPDREIVAVPCRPLIWQNGSLHCVTMQLPRGVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI83</accession>
    <name>A0A0S2DI83_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">LysE family translocator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Translocator protein, LysE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FE772_14815</name>
        <name evidence="6" type="ORF">GLE_2961</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947941.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2961"/>
    <dbReference type="EnsemblBacteria" id="ALN58309">
        <property type="protein sequence ID" value="ALN58309"/>
        <property type="gene ID" value="GLE_2961"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2961"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2922"/>
    <dbReference type="OMA" id="LAVRHWI"/>
    <dbReference type="OrthoDB" id="1927576at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006324">
        <property type="entry name" value="LeuE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="69"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="190"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW26728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="208" mass="22040" checksum="815A68D420951F72" modified="2016-02-17" version="1">MQELLAIVTITTLAVISPGPDFAMVSRNSLLHSRRAGALTALGIALGVWVHVGYTLLGVGLLIRESIQLYAALKLLGALYLIWLGVRMLRSRAHDAPAPNAPNAPVARGDLAALRAGFLTNALNPKCTVFVVSLFLQVVGPDTPLAIKLGYGAFVSGAHLLWFALVALLFSQGAVRARLLRWRVAIDRAFGALLVGFGAVLAGSALRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI97</accession>
    <name>A0A0S2DI97_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_14600</name>
        <name evidence="4" type="ORF">FE772_15295</name>
        <name evidence="2" type="ORF">GLE_3060</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000037">
        <property type="protein sequence ID" value="OPD63209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948013.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000037.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3060"/>
    <dbReference type="EnsemblBacteria" id="ALN58407">
        <property type="protein sequence ID" value="ALN58407"/>
        <property type="gene ID" value="GLE_3060"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63209">
        <property type="protein sequence ID" value="OPD63209"/>
        <property type="gene ID" value="BV903_14600"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3060"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3020"/>
    <dbReference type="OMA" id="IGEDRRF"/>
    <dbReference type="OrthoDB" id="2061303at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010980">
        <property type="entry name" value="Cyt_c/b562"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002321">
        <property type="entry name" value="Cyt_c_II"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47175">
        <property type="entry name" value="SSF47175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51009">
        <property type="entry name" value="CYTCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="150" mass="16202" checksum="EFA805270DDB4EE4" modified="2016-02-17" version="1">MSDTQPTAAAPKRKGNGSKYLFLFLIGLVGGVVATVMAMRALDQRKDHFPDSVMHVQAWHLGELSGKVKQNRCAATDTLPHIKALRTMADDLDPAFPSLKDDQRFSQHSAKMRAALDNALANPPVSCAGVTTVAEQIGEACKACHQDFRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIA1</accession>
    <name>A0A0S2DIA1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter, ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ugpC</name>
        <name evidence="7" type="ORF">FE772_13850</name>
        <name evidence="6" type="ORF">GLE_2773</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947803.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2773"/>
    <dbReference type="EnsemblBacteria" id="ALN58121">
        <property type="protein sequence ID" value="ALN58121"/>
        <property type="gene ID" value="GLE_2773"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2773"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2730"/>
    <dbReference type="OMA" id="ETILYAS"/>
    <dbReference type="OrthoDB" id="1200451at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03301">
        <property type="entry name" value="ABC_MalK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015855">
        <property type="entry name" value="ABC_transpr_MalK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW26583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="364" mass="40111" checksum="7616B8F07D2CEF75" modified="2016-02-17" version="1">MAKVSLQHLRKVYPNGYVGVADASFDIADGELLVLVGPSGCGKSTLLRMIAGLETISGGELRIGERLVNQVPPKDRDIAMVFQSYALYPHMTVAENLGFGLKLRGLGKAEIARQVGEAAAMLELEPLLERKPAALSGGQRQRVALGRALVRKAQVFLLDEPLSNLDAKLRMTMRVEIARLHRQLGTTMVYVTHDQVEAMTLGHRIVVMKEGKIQQIDTPMELYNRPVNLFVATFLGSPKMNVLWGPVVERDDGLHLQIGEGVQLRLRPQGELLEKVRGYLGRELMVGLRPEDLHLADAGPDTLPAKVEVVEPVGNEAFLNLGCGGCDLVVRLPPFHLPQAGDTVHLSYAAERMHFFDRQSELRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIH1</accession>
    <name>A0A0S2DIH1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AHS1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_3140</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3140"/>
    <dbReference type="EnsemblBacteria" id="ALN58487">
        <property type="protein sequence ID" value="ALN58487"/>
        <property type="gene ID" value="GLE_3140"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3140"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3098"/>
    <dbReference type="OMA" id="MPWMLAA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003833">
        <property type="entry name" value="CT_C_D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010016">
        <property type="entry name" value="KipI_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34698">
        <property type="entry name" value="PTHR34698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02682">
        <property type="entry name" value="CT_C_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00796">
        <property type="entry name" value="AHS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00370">
        <property type="entry name" value="TIGR00370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AHS1" evidence="4">
        <location>
            <begin position="22"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="255" mass="26764" checksum="CD68B44F38BB5D8E" modified="2016-02-17" version="1">MNDPAANPAGADRRPREGAAAVEFEALADDAWLLRLGERIDDALNARVHALAARVRAPAPPWLRDLVPAYASLAVFFDPAQTDAATVRDWLLQRCGESVDGGNIAAAGAARVVEIPVAYGGEFGPDLDEAASQLGLTAAQLVERHSGGDYRVAMIGFAPGFPYLSGLDPALALPRLASPRTQVAAGSVAIGGAQTGIYPRPGPGGWRLLGRTPLRLFDARREAPSLLQPGDRVRLRAIGADEFHALSDPARATPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DII5</accession>
    <name>A0A0S2DII5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2998</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58346">
        <property type="protein sequence ID" value="ALN58346"/>
        <property type="gene ID" value="GLE_2998"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2998"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2959"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="45" mass="4681" checksum="38D7B6B8198F01B7" modified="2016-02-17" version="1">MRFPPGGAGDGAGARSGGPRPGRDAAGSRRLGRNRRPPRRRAADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIK1</accession>
    <name>A0A0S2DIK1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Toxic anion resistance</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Toxic anion resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">telA</name>
        <name evidence="2" type="ORF">FE772_15075</name>
        <name evidence="1" type="ORF">GLE_3016</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947983.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3016"/>
    <dbReference type="EnsemblBacteria" id="ALN58364">
        <property type="protein sequence ID" value="ALN58364"/>
        <property type="gene ID" value="GLE_3016"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3016"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2977"/>
    <dbReference type="OMA" id="QGYLAMD"/>
    <dbReference type="OrthoDB" id="498244at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008863">
        <property type="entry name" value="Toxic_anion-R_TelA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38432">
        <property type="entry name" value="PTHR38432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05816">
        <property type="entry name" value="TelA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="408" mass="44475" checksum="BA7AF4FF4D5EE10F" modified="2016-02-17" version="1">MSTTQTPGTTTLLAEPVAPLTLDMPEPALTVAEPDQAAAMIPFKDETRTQVLSQADQFIADLLALDPHSEDFRSRVDSAFRLGRKEIGDSTLLTNKFLDRNFVADADSPAFKVMSEMRILFEDLNPSKEGDLLAAHKLLGLIPFGNKLRAYLQRFDSAGDSIRKTIDSLYGVQDELARDDQALYATMQKLLEALTRLKAADVFAEQLDGKLSAALDSLKAADPARAKAVEQEVLFYVRQASVDIKTQILVCINGYKMLEGLRKTGRELRNGCDRMATIGMSSLSIAATLARAQGYQLQVMDALKSSSRAIEGLIASTSTQFGQHVDRVAEFQSNPLIGVQTLQNAFDTTFAALDRMDEFRSKAIGAMGTNIEQLRGLIAKGEARMNREREAVAAVRQSIAAPAGPVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIP8</accession>
    <name>A0A0S2DIP8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAD assembly factor SdhE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_15200</name>
        <name evidence="4" type="ORF">GLE_3041</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SdhE FAD assembly factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947999.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3041"/>
    <dbReference type="EnsemblBacteria" id="ALN58388">
        <property type="protein sequence ID" value="ALN58388"/>
        <property type="gene ID" value="GLE_3041"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3041"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3001"/>
    <dbReference type="OMA" id="FEHEYDT"/>
    <dbReference type="OrthoDB" id="2055100at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005631">
        <property type="entry name" value="SDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036714">
        <property type="entry name" value="SDH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03937">
        <property type="entry name" value="Sdh5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109910">
        <property type="entry name" value="SSF109910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="90" mass="10981" checksum="29FCFEF675EC11C1" modified="2016-02-17" version="1">MSDTPSADERDELELRRLRWRCRRGMRELDQLFGRYLDRAWRASSEHERGLFLRLLETEDDKLWHWFMGHEEAQDAQLQALVEKIRNLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-06-17" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIQ2</accession>
    <name>A0A0S2DIQ2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF5625 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3188</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58534">
        <property type="protein sequence ID" value="ALN58534"/>
        <property type="gene ID" value="GLE_3188"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3188"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3142"/>
    <dbReference type="OrthoDB" id="2102278at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041008">
        <property type="entry name" value="DUF5625"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18539">
        <property type="entry name" value="DUF5625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5625" evidence="2">
        <location>
            <begin position="34"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="216" mass="23900" checksum="AB3710AE40E84EEF" modified="2016-02-17" version="1">MRIALAVFALALLARIGFELWADEVQGEPLDDAPIAVASGGALDARIRLRVRDSYRMQLVFLIPPDGRERLRNLLAEPVPRGGPPVSEGVVVPLRWSLSEADSGRVVAQGEPRTEGLDAWNSDMFWREAASFAAKPGWYRLRVQATRPVPELAGVTTLINVGLRPKASSSWQTEWAWFGRLLCLLLDPLLLLAGLLLAWFVGRRLWFARRAIAAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIY3</accession>
    <name>A0A0S2DIY3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58597">
        <property type="protein sequence ID" value="ALN58597"/>
        <property type="gene ID" value="GLE_3251"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3251"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3205"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="44" mass="4800" checksum="1204E6DD0BCE745C" modified="2016-02-17" version="1">MQPADQAAFGVPMQASKPRSCESHDPWLHRDKAVSFGTRACALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ54</accession>
    <name>A0A0S2DJ54_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phosphate transport system permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">pstC</name>
        <name evidence="12" type="ORF">FE772_16395</name>
        <name evidence="11" type="ORF">GLE_3315</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948201.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3315"/>
    <dbReference type="EnsemblBacteria" id="ALN58661">
        <property type="protein sequence ID" value="ALN58661"/>
        <property type="gene ID" value="GLE_3315"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3315"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3265"/>
    <dbReference type="OMA" id="VIRMSVL"/>
    <dbReference type="OrthoDB" id="1325025at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MetI-like"/>
    </dbReference>
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        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011864">
        <property type="entry name" value="Phosphate_PstC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02138">
        <property type="entry name" value="phosphate_pstC"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
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    <keyword evidence="9" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="26"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="83"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="120"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="292"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="83"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN58661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW26981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="324" mass="34829" checksum="627C40DD720043D9" modified="2016-02-17" version="1">MNATALPAQTGTSSARDVKDARQDRLFRYVLTATVVFVLIALASAALSMLWGGRHVLEEEGLDFFITAQWNPVENHYGALVPIYGTIVTALIAMVIAVPVSFGIAFFLTEVAPRWARGPIGTAIELLAGIPSIIYGMWGLFVLVPVMTEYVTPWLNDNIGTWPVIGALFQGPPLGIGMLTAGIVLAIMVIPFISSVMREVFLTVPTRLKESAYALGSTKWEVSWDIVLPYTRSAVIGGIFLGLGRALGETMAVAFVIGNSVNFSASLLEPGTTIAALIANDFGEATETYRSALLLLGFVLFIVTFVVLAAARLMLMQLARKEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJF9</accession>
    <name>A0A0S2DJF9_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_15875</name>
        <name evidence="2" type="ORF">GLE_3195</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW26897.1"/>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN58541">
        <property type="protein sequence ID" value="ALN58541"/>
        <property type="gene ID" value="GLE_3195"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3195"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3150"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242235" evidence="1">
        <location>
            <begin position="29"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="75" mass="8078" checksum="365DDAD2AED45845" modified="2016-02-17" version="1">MKRLFEGKRTLLLALAGVATFAAGFAYAAAHPCVECGIERDRCLASGTNPTLCQAMYKTCWQENGCNPTNPGNPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJJ8</accession>
    <name>A0A0S2DJJ8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 4" type="primary">rpsP</name>
        <name evidence="5" type="ORF">BV903_24620</name>
        <name evidence="6" type="ORF">FE772_16125</name>
        <name evidence="4" type="ORF">GLE_3255</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">C3</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial ribosomal protein bS16 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000096">
        <property type="protein sequence ID" value="OPD61260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948155.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000096.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3255"/>
    <dbReference type="EnsemblBacteria" id="ALN58601">
        <property type="protein sequence ID" value="ALN58601"/>
        <property type="gene ID" value="GLE_3255"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61260">
        <property type="protein sequence ID" value="OPD61260"/>
        <property type="gene ID" value="BV903_24620"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3255"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3209"/>
    <dbReference type="OMA" id="GFYNPIA"/>
    <dbReference type="OrthoDB" id="1937072at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00385">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000307">
        <property type="entry name" value="Ribosomal_S16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020592">
        <property type="entry name" value="Ribosomal_S16_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023803">
        <property type="entry name" value="Ribosomal_S16_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12919">
        <property type="entry name" value="PTHR12919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00886">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54565">
        <property type="entry name" value="SSF54565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00002">
        <property type="entry name" value="S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00732">
        <property type="entry name" value="RIBOSOMAL_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD61260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW26935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="85" mass="9489" checksum="91109FEDC413CF62" modified="2016-02-17" version="1">MVKIRLTRGGAKKRPFYHIIVTDSRSARDGRNIERVGFYNPVAAGNEKRVELNLDRVKHWVANGAQLTDKVADLYKQAVKAAPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJN5</accession>
    <name>A0A0S2DJN5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome-recycling factor</fullName>
            <shortName evidence="3">RRF</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Ribosome-releasing factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">frr</name>
        <name evidence="6" type="ORF">BV903_17725</name>
        <name evidence="7" type="ORF">FE772_16650</name>
        <name evidence="5" type="ORF">GLE_3374</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the RRF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <source>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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        <source>
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    </evidence>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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        <source>
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    </evidence>
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</entry>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <source>
            <dbReference type="EMBL" id="ALN59067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="43" mass="5156" checksum="FBE96ABB415805F3" modified="2016-02-17" version="1">MEELQPIRLRLQRQHALGFDRFREMIEGQLQRRAGPAKIGRPR</sequence>
</entry>
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    <accession>A0A0S2DKF8</accession>
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    <protein>
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        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">FE772_17885</name>
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="DUF819"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="303"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="329"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="419" mass="44092" checksum="366A6A8E2B3E42FB" modified="2016-02-17" version="1">MPDTARTALISNDIVVLGLIAATLGLVFWTSAQQTGFWKKFYTFVPALLLCYFIPGIYNTVGLVDGNNTKLYNPVASRVLLPAALVLLTLTIDLKGVLKLGPKLLIMYAVSSLSVAFGAIVAFVVMRAVHPETVAGDTWGGMAALAGSWIGGGANMLAMKEIFQVDATTFGQFAVVDVGVGYVWMAALIFLASRAQAIDARSGADVSGIEELKQRIEHFRAQHERVASLTDLAMIVGIAFGVVGLAHAIAGPLSAWFGANVSWARTVSLHEPFFWVVAVSTFAGLGLSFTRARQLEGAGASKIGSLLLYFLIACIGLQMDILALLDKPWLFALGIIWIAVHIAILWGVGRLLKVPLFYFAIGSQSNIGGPASAPVVASAFHPSLAPVGALLGTLGYATGTGLAYLVGITLRSIAGDTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKL2</accession>
    <name>A0A0S2DKL2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3754</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948525.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59098">
        <property type="protein sequence ID" value="ALN59098"/>
        <property type="gene ID" value="GLE_3754"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3754"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3698"/>
    <dbReference type="OrthoDB" id="2165004at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="192" mass="20461" checksum="01B9FC92AA9DC8A9" modified="2016-02-17" version="1">MELHSLIWWLAGLVPGLALGWWLRARIAAKQPIRQIADAPGPQPLRPASEPAPQAVAAPSTPAAVPAPAPADSAPMVSSLEPAPAEPAPTEPAPAEPAPPAWPEAVQELFDRGQAVEAIVLIRRTLGAPLARKAARERFADPGASAPLPAEVRKLADDGKKLDAIRRLCDLTHMDLPLAQRLVEHYVAHPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKL9</accession>
    <name>A0A0S2DKL9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3447</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58792">
        <property type="protein sequence ID" value="ALN58792"/>
        <property type="gene ID" value="GLE_3447"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3447"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="504"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="510"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="524" mass="57122" checksum="3364A9AFE99483FA" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLL8</accession>
    <name>A0A0S2DLL8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">H-NS histone family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">H-NS histone family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BV903_25170</name>
        <name evidence="9" type="ORF">FE772_19585</name>
        <name evidence="7" type="ORF">GLE_3995</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histone-like protein H-NS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000106">
        <property type="protein sequence ID" value="OPD61153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948700.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000106.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59337">
        <property type="protein sequence ID" value="ALN59337"/>
        <property type="gene ID" value="GLE_3995"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61153">
        <property type="protein sequence ID" value="OPD61153"/>
        <property type="gene ID" value="BV903_25170"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3995"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3932"/>
    <dbReference type="OMA" id="MPRWLAS"/>
    <dbReference type="OrthoDB" id="1911889at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009295">
        <property type="term" value="C:nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027444">
        <property type="entry name" value="H-NS_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037150">
        <property type="entry name" value="H-NS_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001801">
        <property type="entry name" value="Histone_HNS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00816">
        <property type="entry name" value="Histone_HNS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00528">
        <property type="entry name" value="HNS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNS" evidence="6">
        <location>
            <begin position="71"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="65"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="76"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD61153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW27512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="139" mass="15576" checksum="25A748E6CE198879" modified="2016-02-17" version="1">MNIDIEKLGLRELTALLSAAEQRKQLLAKRRSPALVRRKAAALAAQHGYTIEELFGDQPVAEIAAKKRSPRRKPSKVAAKYRDPDNKRNTWSGRGRMPRWLAQKTKHGRSATDFLIPGLAKPTARKTNSIGRRTLVKQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLN1</accession>
    <name>A0A0S2DLN1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cell division protein FtsQ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ftsQ</name>
        <name evidence="10" type="ORF">GLE_4128</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of a complex composed of FtsB, FtsL and FtsQ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <text evidence="8">Localizes to the division septum.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the FtsQ/DivIB family. FtsQ subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4128"/>
    <dbReference type="EnsemblBacteria" id="ALN59470">
        <property type="protein sequence ID" value="ALN59470"/>
        <property type="gene ID" value="GLE_4128"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4128"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4070"/>
    <dbReference type="OMA" id="MARIQRF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090529">
        <property type="term" value="P:cell septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00911">
        <property type="entry name" value="FtsQ_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005548">
        <property type="entry name" value="Cell_div_FtsQ/DivIB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026579">
        <property type="entry name" value="FtsQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045335">
        <property type="entry name" value="FtsQ_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034746">
        <property type="entry name" value="POTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013685">
        <property type="entry name" value="POTRA_FtsQ_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35851">
        <property type="entry name" value="PTHR35851"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03799">
        <property type="entry name" value="FtsQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08478">
        <property type="entry name" value="POTRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51779">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 8 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="POTRA" evidence="9">
        <location>
            <begin position="23"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="236" mass="26468" checksum="230AFA4BE0706DBA" modified="2016-02-17" version="1">MALVLVALPVVAVLNGWIGANQWPLKRLRVTGEFERVDAASLRKTLLPYAQRGFFAVDLPKAQDAVSKLPWVERAEVRKRWPDVLEVTVVEHKPFARWGEDRLLSEQGRLFPIGKDLQVPDKLPRFGGPESRVADVVALYNESRELFAPVGLEVRDVEVDQRGSWTMGLSNGARIVIGRTEQRSRLSRFVHMLPQLTAQKAQVLERADLRYTNGFSLTWAPAQQAPAAAPKQQGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLR0</accession>
    <name>A0A0S2DLR0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Homogentisate 1,2-dioxygenase</fullName>
            <shortName evidence="6">HGDO</shortName>
            <ecNumber evidence="6">1.13.11.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Homogentisate oxygenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Homogentisic acid oxidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Homogentisicase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">hmgA</name>
        <name evidence="9" type="ORF">FE772_21055</name>
        <name evidence="8" type="ORF">GLE_4302</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>homogentisate + O2 = 4-maleylacetoacetate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15449"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16169"/>
            <dbReference type="ChEBI" id="CHEBI:17105"/>
            <dbReference type="EC" id="1.13.11.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 4/6.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Hexamer; dimer of trimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the homogentisate dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.5" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4302"/>
    <dbReference type="EnsemblBacteria" id="ALN59643">
        <property type="protein sequence ID" value="ALN59643"/>
        <property type="gene ID" value="GLE_4302"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4302"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4241"/>
    <dbReference type="OMA" id="FMFETRW"/>
    <dbReference type="UniPathway" id="UPA00139">
        <property type="reaction ID" value="UER00339"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004411">
        <property type="term" value="F:homogentisate 1,2-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006572">
        <property type="term" value="P:tyrosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00334">
        <property type="entry name" value="Homogentis_dioxygen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005708">
        <property type="entry name" value="Homogentis_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022950">
        <property type="entry name" value="Homogentis_dOase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11056">
        <property type="entry name" value="PTHR11056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04209">
        <property type="entry name" value="HgmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01015">
        <property type="entry name" value="hmgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 6" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="392"/>
        </location>
        <ligand>
            <name>homogentisate</name>
            <dbReference type="ChEBI" id="CHEBI:16169"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="411"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW27763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="460" mass="50271" checksum="BC8FE0B1DFEADA18" modified="2016-02-17" version="1">MSTAANDIDNVIPMPSTDSVRQRPRGYMSGFGNEFATEAVAGALPEGQNSPQRAPFGLYAEQLSGTAFTAPRKENRRSWLYRIRPAAMHGAFSPFAQPRFHNDFGDGPVSPDQLRWDPLPLPLSESGSEGGVDFVDGLYTMAGNGSAAGQHGCGIHLYAANRSMQGRFFYNADGETLIVPQLGRLLIGTELGALEVEPMEVAVIPRGIRFRVELVDGASRGYVCENFGALLRLPDLGPIGSNGLANPRDFSTPHASYEDLEGTFELVAKFQGHLWRADIGHSPLDVVAWHGNFAPYKYDLRRFNTIGSISFDHPDPSIFTVLTSPSDTPGTANIDFVIFPPRWLVAQHTFRPPWFHRNVASEFMGLVHGVYDAKAGGFAPGGASLHNCMTGHGPDAETFEKASHADLSKPHVITDTMAFMFETRAVIRPAAQAFDAAHRQRDYQACWAGLQKHFDPVGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLT1</accession>
    <name>A0A0S2DLT1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyl transferase family 2</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase, group 2 family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_04410</name>
        <name evidence="5" type="ORF">FE772_20750</name>
        <name evidence="3" type="ORF">GLE_4237</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000008">
        <property type="protein sequence ID" value="OPD65168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948893.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000008.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4237"/>
    <dbReference type="EnsemblBacteria" id="ALN59578">
        <property type="protein sequence ID" value="ALN59578"/>
        <property type="gene ID" value="GLE_4237"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65168">
        <property type="protein sequence ID" value="OPD65168"/>
        <property type="gene ID" value="BV903_04410"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4237"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4178"/>
    <dbReference type="OMA" id="MLFRLNT"/>
    <dbReference type="OrthoDB" id="1064289at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="17"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD65168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW27706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="340" mass="37231" checksum="C6CF64B660C7DA46" modified="2016-02-17" version="1">MTRDANAPCSWTSGIAVVIPSYKVTRHILGVLAAIGPEVDAVYCVDDACPDNSGEFIERNATDPRVRVLRNPHNQGVGGAMITGYQQAIADGATVIVKIDGDGQMDPALLPAFVAPILAGEADYTKGNRFWDLAQIRQMPLARRIGNLGLSFMAKASTGYWDVFDPTNGYTAIHARVAAMLPFNSISKRYFFETDILFRLNTVRAVVIDVPMDARYGDETSGLKASKIFFEFLFKHARNLGKRVGYNYFLRDLSLASLELLAAVLLLGFGLGFGGWHWVRSVQAESATPVGTVMIATVAVVSGLQFLLAFFGYDIASVPRRPLSQLLARRPLIKRISHDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM26</accession>
    <name>A0A0S2DM26_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6 8">Proline iminopeptidase</fullName>
            <shortName evidence="6">PIP</shortName>
            <ecNumber evidence="4 6 8">3.4.11.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Prolyl aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pip</name>
        <name evidence="11" type="ORF">FE772_19070</name>
        <name evidence="10" type="ORF">GLE_3881</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6 8">
            <text>Release of N-terminal proline from a peptide.</text>
            <dbReference type="EC" id="3.4.11.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6 8">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.5" evidence="4 6 8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948619.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3881"/>
    <dbReference type="EnsemblBacteria" id="ALN59224">
        <property type="protein sequence ID" value="ALN59224"/>
        <property type="gene ID" value="GLE_3881"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3881"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3820"/>
    <dbReference type="OMA" id="FYQDGAS"/>
    <dbReference type="OrthoDB" id="665798at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002410">
        <property type="entry name" value="Peptidase_S33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005944">
        <property type="entry name" value="Pro_iminopeptidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43722">
        <property type="entry name" value="PTHR43722"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006431">
        <property type="entry name" value="Pept_S33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00793">
        <property type="entry name" value="PROAMNOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01249">
        <property type="entry name" value="pro_imino_pep_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 10" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="9">
        <location>
            <begin position="35"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR006431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR006431-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW27426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="313" mass="35524" checksum="7039C3D53E099D5D" modified="2016-02-17" version="1">MRTLYPELEPFDTGTLQVDERHTLHYEQCGNPDGKPVVLLHGGPGAGCSAKMRRFHDPAKYRIVLFDQRGSGRSTPHADLTDNTTWDLVADIEKLRAKLGIERWQVFGGSWGSTLALAYAQTHPQRVTELVLRGIFMLRRWELEWFYQEGASRLFPDAWEHYVNAIPAVERHDLISAFHRRLTSSDEKTRLDAARAWSVWEGATSFLHVDDDFVSGHEDAKFALAFARIENHYFVNGGFFEVEEQLLRDAHKIADIPGAIVHGRYDVVCPVQNAWELKKAWPKAELTITPASGHSAFEAENVDALVRATDRFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMA8</accession>
    <name>A0A0S2DMA8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="4">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_4319</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948958.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4319"/>
    <dbReference type="EnsemblBacteria" id="ALN59660">
        <property type="protein sequence ID" value="ALN59660"/>
        <property type="gene ID" value="GLE_4319"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4319"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4258"/>
    <dbReference type="OMA" id="RAMAQNM"/>
    <dbReference type="OrthoDB" id="1626282at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 4" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="6">
        <location>
            <begin position="4"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="7">
        <location>
            <begin position="153"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="83"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="215"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="455" mass="46934" checksum="DE251AD1D6091CDD" modified="2016-02-17" version="1">MSDTKTFLLPDLGEGLPDATIVEWAVKVGDTIRLDDTLVSMETAKAVVEVPSPVSGKVLKLAGAAGDVIVTGTMLAEFEIDPNMPQRADGQDTGHHHGGGHAAPAAAPAPAKTEEAPAKAEGNERADSGTVVGAMQSSDAVRSEQAVAVGGVKAMPAVRALARKLGVDLGRVRATGADGTVSSDDVKRAAADGSAKIGSAPAAAVAPRAAAVAEAPAPAAAPARSTLSQSGRPMRTQPPGAAVTGQPEQLKGVRRNMARVMADAHSKVVPTTLADDADIHAWLPGNDITGRLVRAIVVACKTVPALNAWFDGDKLTRTLHPHVDIGIAVDTDDGLFVPALRNADVLDPRGVREAINRLRAQVEDRSIPASELSGYTISLSNFGMFAGRYATPVVVPPTVAIVAAGKGRHQMTPVMGGFESHKVIPLSLTFDHRACTGGEAARFLKAMIDDLARAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DME6</accession>
    <name>A0A0S2DME6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RelA/SpoT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_3978</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the relA/spoT family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3978"/>
    <dbReference type="EnsemblBacteria" id="ALN59320">
        <property type="protein sequence ID" value="ALN59320"/>
        <property type="gene ID" value="GLE_3978"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3978"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3916"/>
    <dbReference type="OMA" id="TEIGHNC"/>
    <dbReference type="OrthoDB" id="204079at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00015"/>
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    </dbReference>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="392"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="3">
        <location>
            <begin position="651"/>
            <end position="724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="724" mass="79614" checksum="ACBCB3AFD46DE381" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMH9</accession>
    <name>A0A0S2DMH9_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
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        <lineage>
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        </lineage>
    </organism>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="63" mass="6701" checksum="8B61049159195BE0" modified="2016-02-17" version="1">MSGQEPAARAAVGIDAPRAASAHRQGARPGSRAHCLKRLKRGLQPAGAEPALLRWAAPQPRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMI9</accession>
    <name>A0A0S2DMI9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Prolyl oligopeptidase, N-terminal beta-propeller domain</fullName>
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        <submittedName>
            <fullName evidence="5">S9 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_22155</name>
        <name evidence="4" type="ORF">GLE_4537</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN59878">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        </location>
    </feature>
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            <end position="721"/>
        </location>
    </feature>
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            <end position="439"/>
        </location>
    </feature>
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        <location>
            <begin position="498"/>
            <end position="712"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW27945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="721" mass="81455" checksum="ADAA9B9D7D3D48A7" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMM2</accession>
    <name>A0A0S2DMM2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase, short chain dehydrogenase/reductase family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">SDR family NAD(P)-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_21665</name>
        <name evidence="2" type="ORF">GLE_4437</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
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        <property type="protein sequence ID" value="ALN59778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW27868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949053.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4437"/>
    <dbReference type="EnsemblBacteria" id="ALN59778">
        <property type="protein sequence ID" value="ALN59778"/>
        <property type="gene ID" value="GLE_4437"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4437"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4374"/>
    <dbReference type="OMA" id="LALQYPK"/>
    <dbReference type="OrthoDB" id="968232at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
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    </dbReference>
    <dbReference type="Pfam" id="PF00106">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
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        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="235" mass="24950" checksum="68F7ABA7E95F3E82" modified="2016-02-17" version="1">MTDANDDTRIALVTGGNRGIGLAVCEGFARRGVRVYMGCRDLDEGRAAIKRRGLAGVEPIRLDVCSDASMTAAVGAIADAHGHLDLLVNNAGMSVGVRDKPSDESLAQARATFDVNFFGPWRLSQLALPLMRGRPQAHIINVSSGHGSSTRIEGNNLGYRSSKSALNVLTQAMAAELADSGIRVNCMTPGWVRTKLGGIAAPRSPEEGADTILWLALDGGGETGRFYKDKALFPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMT6</accession>
    <name>A0A0S2DMT6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytidine and deoxycytidylate deaminase zinc-binding region</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Nucleoside deaminase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">tRNA-specific adenosine deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_03560</name>
        <name evidence="4" type="ORF">FE772_22095</name>
        <name evidence="2" type="ORF">GLE_4525</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000006">
        <property type="protein sequence ID" value="OPD65376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949121.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4525"/>
    <dbReference type="EnsemblBacteria" id="ALN59866">
        <property type="protein sequence ID" value="ALN59866"/>
        <property type="gene ID" value="GLE_4525"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65376">
        <property type="protein sequence ID" value="OPD65376"/>
        <property type="gene ID" value="BV903_03560"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4525"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4461"/>
    <dbReference type="OMA" id="AILHAEM"/>
    <dbReference type="OrthoDB" id="1890883at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
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        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="5"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD65376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="151" mass="16533" checksum="B3BBE835287734A8" modified="2016-02-17" version="1">MIATPDYRALLATAVAEARQGIAEGGIPIGAALYHNDGRLLGCGHNRRIQENDPSVHGETDAFRKAGRQRRYRDTIMVTTLAPCWYCSGLVRQFNIGTVVVGESVNFRGGIDWLRESGVEVIDLADQECIDLLGGYIAANPEVWNEDIGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMZ6</accession>
    <name>A0A0S2DMZ6_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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        <name evidence="3" type="ORF">GLE_4516</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59857">
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        <property type="gene ID" value="GLE_4516"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4516"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4452"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242256" evidence="2">
        <location>
            <begin position="26"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="230" mass="24472" checksum="58AAA4235276EA5E" modified="2016-02-17" version="1">MHEPGCFRWLVALALATGACGVAQAQAQATSAPSAVAPAALDPPARPTTPESASGAPQPGSLRARALSALDGAEDLTLYSLQPWEPPPSPPQWQDLSAVELSRREASLEQRSRRDWCKRERCFHDQRVLGRTRLAAADRPAVRAALAQALGQVPDASSLCMPSYRHAVSFVSAGLRYEVLLCYQCDQIAVAAGREREAGDSGGLGDRAAVDAILRRAGIALAKSAYDEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNC0</accession>
    <name>A0A0S2DNC0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TetR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">TetR/AcrR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BV903_15855</name>
        <name evidence="6" type="ORF">FE772_22815</name>
        <name evidence="4" type="ORF">GLE_4687</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">C3</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000041">
        <property type="protein sequence ID" value="OPD62945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949237.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4687"/>
    <dbReference type="EnsemblBacteria" id="ALN60028">
        <property type="protein sequence ID" value="ALN60028"/>
        <property type="gene ID" value="GLE_4687"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62945">
        <property type="protein sequence ID" value="OPD62945"/>
        <property type="gene ID" value="BV903_15855"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4687"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4622"/>
    <dbReference type="OMA" id="PGNIYRY"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039538">
        <property type="entry name" value="BetI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13977">
        <property type="entry name" value="TetR_C_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="20"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="2">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD62945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW28051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="210" mass="22277" checksum="16AEC6CDA232AD5B" modified="2016-02-17" version="1">MSSPGNTTAKPSAKAAARAQAQRERILVAAQRCFVVHGFHAASMANIAETAGMSAGLIYRYFKGKNDIILAIIERQLEEARADVAKLNTSSDLVGGIAEVFQQWQANDPGITSAALFLELTAEATRDPEIAAATHASDKVFRADLASWFARSAAEGGLGVPQDQVGTRVLILQSLIEGLAMRAISQPDLTVDQVKTALSQFLPSLLTAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNH1</accession>
    <name>A0A0S2DNH1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4926</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949421.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60267">
        <property type="protein sequence ID" value="ALN60267"/>
        <property type="gene ID" value="GLE_4926"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4926"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4855"/>
    <dbReference type="OrthoDB" id="322125at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="287"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="577"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="585"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="601" mass="62529" checksum="CCB39EC55DD274D7" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNI2</accession>
    <name>A0A0S2DNI2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flavohemoglobin expression-modulating QEGLA motif protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_23280</name>
        <name evidence="1" type="ORF">GLE_4785</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949314.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4785"/>
    <dbReference type="EnsemblBacteria" id="ALN60126">
        <property type="protein sequence ID" value="ALN60126"/>
        <property type="gene ID" value="GLE_4785"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4785"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4718"/>
    <dbReference type="OMA" id="FIMVYNY"/>
    <dbReference type="OrthoDB" id="859435at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012656">
        <property type="entry name" value="CHP02421_QEGLA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012548">
        <property type="entry name" value="DUF1704"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31817">
        <property type="entry name" value="PTHR31817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08014">
        <property type="entry name" value="DUF1704"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01154">
        <property type="entry name" value="DUF1704"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02421">
        <property type="entry name" value="QEGLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="424" mass="46575" checksum="109D4B7C577EC3B8" modified="2016-02-17" version="1">MSALPIELSPDLQHHAELDARMVRAARGIKLLTMASWPAGLEVKFLADYARGAATLPVIDYPKHDFSEVRAELEAIAQAADPDHPLGEYLIESAHSWGIAAQLLECLGTRRVTDFSVQLFGKPDVALPGQGPSTREAANHFISIANELDRELMSPAETVQISATALSLQLQRDLDDYFDSRVIDVVLDPDLIAKAAAGATRIRLRSGAAFSDYDRHQLLQHEAFVHSLTALNGRLQPVLPSLALSSPRSTATQEGLATFAEQITGSIDIGRMKRLSLRIDAVAMALDGADFIQVFRYFIDAGQSPDDSFASAQRVFRGVPTDGGAAFTKDTVYLRGLVGVHTFFRWALRQQKLHLCRWLFAGKMTLGDVQRFEPLFQAGVLAPPRWMPPWITRANGLAGMLAFSLFANRIRLDHMAEGDFSEIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNI8</accession>
    <name>A0A0S2DNI8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent protease ATPase subunit HslU</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Unfoldase HslU</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">hslU</name>
        <name evidence="9" type="ORF">GLE_4530</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the ClpX chaperone family. HslU subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4530"/>
    <dbReference type="EnsemblBacteria" id="ALN59871">
        <property type="protein sequence ID" value="ALN59871"/>
        <property type="gene ID" value="GLE_4530"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4530"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4466"/>
    <dbReference type="OMA" id="KYGMIKT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009376">
        <property type="term" value="C:HslUV protease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036402">
        <property type="term" value="F:proteasome-activating activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043335">
        <property type="term" value="P:protein unfolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00249">
        <property type="entry name" value="HslU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004491">
        <property type="entry name" value="HslU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102:SF3">
        <property type="entry name" value="PTHR48102:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00390">
        <property type="entry name" value="hslU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="AAA" evidence="7">
        <location>
            <begin position="55"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="ClpB_D2-small" evidence="8">
        <location>
            <begin position="350"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="66"/>
            <end position="71"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="336"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="408"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN59871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="458" mass="50737" checksum="4E0743D909BDAC74" modified="2016-02-17" version="1">MKPDNSHATMTPREIVQELDRHIVGQHSAKRAVAIALRNRWRRMQLPAELRNEVMPKNILMIGPTGVGKTEIARRLATLANAPFVKVEATRFTEVGYVGKDVEQIVRDLADTAVKLYREQAKVRVRVQAEERAEDRILDALLPKRVPGGFGFGSETPAADHSAPDSDTRAKLRKQLRSGELDEREIEIETAVNLGGVDIMAPPGMEEMGQQLRQMFSQVSGGKTHKKHLSIKAARPQLIEEEAAKLVNEDDVRQAAIEACEQHGIVFIDEIDKVAKRSEAGVSGGDVSREGVQRDLLPLVEGSTVSTKYGAVKTDHILFIASGAFHLAKPSDLIPELQGRFPIRVELGALSKDDFVRILTEPKAALTTQYVELLRTEGVTLEFTGDAVDRLAEIAAQVNERQENIGARRLHTVLERLLDVLSYEAPDRDGQAVTIDKAYVDQHLGELVKDPDLSRYIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNK8</accession>
    <name>A0A0S2DNK8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pyridoxal-dependent decarboxylase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_4817</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the group II decarboxylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4817"/>
    <dbReference type="EnsemblBacteria" id="ALN60158">
        <property type="protein sequence ID" value="ALN60158"/>
        <property type="gene ID" value="GLE_4817"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4817"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4748"/>
    <dbReference type="OMA" id="TNWVDSI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016830">
        <property type="term" value="F:carbon-carbon lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN60158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="568" mass="63125" checksum="E864F19C6CF39156" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNY3</accession>
    <name>A0A0S2DNY3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60276">
        <property type="protein sequence ID" value="ALN60276"/>
        <property type="gene ID" value="GLE_4935"/>
    </dbReference>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="41" mass="4370" checksum="41BECF22FC939207" modified="2016-02-17" version="1">MCLHGAVCAVGFIFAPQHAPRAPGSWEHLNRKGGERGVVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
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            <taxon>Proteobacteria</taxon>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
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            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="133" mass="14604" checksum="FF49FD8DC9F2F8C7" modified="2016-02-17" version="1">MRNRRPYTQTRGASRAGRVRARKRDFGPGRSFARTHRNRPRAPETPDSRDPHHASAAQPSCPARAFDFHGNRAALRHRVHHVDSAVIAGLQAGRIFRPAPLQGAPAPRQRQDRHATGLAAGAGRGCCDDRGQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPH7</accession>
    <name>A0A0S2DPH7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4960</name>
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    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
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            <end position="255"/>
        </location>
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            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="433" mass="48088" checksum="0291E6C738598DDA" modified="2016-02-17" version="1">MSASDPRRSPRLRETLDWPAFVAQDWDRRPVLFKGVAHGRPFALDEVFRSAVAAAARSRRRLPEEPDNTVLTLGRLQQLDPAPWMPRREDASLDGYRQRMLAALGERRYALVISAFHSYRWPLWRSERAFFAPLWREAGLPVTGAITTLFHGNYESTPVGVHRDRFATFMVPVQGRKRMRFWTRKPWREAISTLPDYRAHLDSSFLVEAEPGDVLYWPADYYHVGESVDGGVCTSVNLGVPRHEHRPVYELEDLMVDLGRADAQIDPAAQLLRAALPADLAVLAPARIGADGVLAEALPPALRAALDSARAMAAPAALRTRVRAVSLQRLSAGGFEPPPARAPARAFAADARVALIDTVLRRREPGGWRFAAHGHGLRVDGEAAAERALLARLDPGAPVPVRELLRGRAGERRAAAALLAWLDECRALRRLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPJ3</accession>
    <name>A0A0S2DPJ3_LYSEN</name>
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        <submittedName>
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    </protein>
    <gene>
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    </gene>
    <organism evidence="9 10">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TonB-dependent receptor family.</text>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0798">TonB box</keyword>
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        <location>
            <begin position="1"/>
            <end position="23"/>
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        </location>
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            <begin position="308"/>
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        </location>
    </feature>
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            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU003357"/>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN60474.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="893" mass="96957" checksum="B76684B35C90C4D3" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPM5</accession>
    <name>A0A0S2DPM5_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">V4R domain</fullName>
        </submittedName>
    </protein>
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    </gene>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
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        <property type="protein sequence ID" value="ALN60562"/>
        <property type="gene ID" value="GLE_5221"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5221"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5139"/>
    <dbReference type="OrthoDB" id="1676460at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
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            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="267" mass="28959" checksum="26BC7446331E97BA" modified="2016-02-17" version="1">MVDVEFRVVSERRDGLLLALGQVVIANGFTLLRQRMLNSDEGVVLVMVVRGPADQLLVLEEKLGTHHLVQSFEASPYEGGSAPPPPVRANGAGNGNGHASAPPPPAPSAPPLAPTPATAAPIDVQRVETLLPQLARNYPNILLQLVALERELPPAQREATLRYIGQRVGAWVYKRDFALGGQLPLADSVRRIALPAMRQLVQAELQDDVLRVRNSPFCHRGEHGECCHFLRGMLGGLLEGQHGGTVRVVESQCRNTGAETCRFEFEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPP0</accession>
    <name>A0A0S2DPP0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5289</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60630">
        <property type="protein sequence ID" value="ALN60630"/>
        <property type="gene ID" value="GLE_5289"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5289"/>
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    <dbReference type="OMA" id="KYAGATM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595944" evidence="1">
        <location>
            <begin position="24"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="246" mass="24266" checksum="18A72E67CC8EB92F" modified="2016-02-17" version="1">MKRPSLRLALLLALAAATPPASALPPLRADLVDDATLAALNGRYFDAQMLVGLRVDLISSVATPQQGAAMASGSLLVLRDGAGFSVRSDARSQAAAGVGADASAAAASGAESVRMHGIGQLAQIAGDGNRLSNLAAIEFVDAAGLAAGAGGFNGRTHSDSAAGALRAQVTFLDGAAAVGVQAPGVSLQQRLDGGLGGIAQSGHIAGEGVAAGNRLQLQIATAPMTPQLGRELGLLQALAGLRGVPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPQ5</accession>
    <name>A0A0S2DPQ5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_11090</name>
        <name evidence="1" type="ORF">GLE_5107</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000026">
        <property type="protein sequence ID" value="OPD63847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949559.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60448">
        <property type="protein sequence ID" value="ALN60448"/>
        <property type="gene ID" value="GLE_5107"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63847">
        <property type="protein sequence ID" value="OPD63847"/>
        <property type="gene ID" value="BV903_11090"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5107"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5032"/>
    <dbReference type="OrthoDB" id="1539723at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD63847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="215" mass="23486" checksum="022FD02986559AC5" modified="2016-02-17" version="1">MSAAALRAVLAETDASWHGLGEDERIAPELLAAGRESAIGRRLLGAWLAAEAAPALLAPQPGAGFAAAALRWPRARVERLVRDLGALAYAPAIRAEVRREPVRRLKQALDNAYLLALDSQVWDGKVQNQLALQLGEHLDRALRAADDAPLYALLDLRGRAELRLWAERRDPGLADWARLLLPRHLHDEAPALVAHLPPDVVERLHTHHGARPLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPV3</accession>
    <name>A0A0S2DPV3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator FeaR</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">feaR</name>
        <name evidence="4" type="ORF">FE772_25650</name>
        <name evidence="3" type="ORF">GLE_5306</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949707.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60647">
        <property type="protein sequence ID" value="ALN60647"/>
        <property type="gene ID" value="GLE_5306"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5306"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5224"/>
    <dbReference type="OMA" id="MLHVLMD"/>
    <dbReference type="OrthoDB" id="1785082at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035418">
        <property type="entry name" value="AraC-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14525">
        <property type="entry name" value="AraC_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="213"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="321" mass="35772" checksum="5C50EDEB9BCFDDA4" modified="2016-02-17" version="1">MFQQVCSTHDIDTWSRSLQGVCGLFETQPAHEHSLFIGDLRYRDFAELRLARIRTNAARLLYRAPGGDRLDDRYCFLVMQTYGRSRIRQDGETTELSPGSLALIDPTRSCEILPQGLMEHASLHLERSRVCRSLRGAARSFGKIGAGSVSARLLRGLVEQLADSTLPAHATCGEEGAALQEALLQLLAPAWKAARPHGEADAEAGTPAAALRERACRLIDECLPDPCLGPKLVARQLGTSLRQLHRLFEESDESVSRYILHRRLERAASNLGDPALTSRSITELAYRWGFTDSTHFSRIFKRRYDCSPRQYRSRALAVAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ12</accession>
    <name>A0A0S2DQ12_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">GlsB/YeaQ/YmgE family stress response membrane protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Transglycosylase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Transglycosylase-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BV903_12265</name>
        <name evidence="11" type="ORF">D9T17_04530</name>
        <name evidence="10" type="ORF">FE772_24295</name>
        <name evidence="8" type="ORF">GLE_5010</name>
    </gene>
    <organism evidence="8 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 12">C3</strain>
        </source>
    </reference>
    <reference evidence="9 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">OH11</strain>
        </source>
    </reference>
    <reference evidence="10 15" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 15">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0410 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000029">
        <property type="protein sequence ID" value="OPD63690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000013">
        <property type="protein sequence ID" value="ROU08342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949485.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000013.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60351">
        <property type="protein sequence ID" value="ALN60351"/>
        <property type="gene ID" value="GLE_5010"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63690">
        <property type="protein sequence ID" value="OPD63690"/>
        <property type="gene ID" value="BV903_12265"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5010"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4938"/>
    <dbReference type="OMA" id="GGGWWFT"/>
    <dbReference type="OrthoDB" id="2084822at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007341">
        <property type="entry name" value="Transgly_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33884">
        <property type="entry name" value="PTHR33884"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04226">
        <property type="entry name" value="Transgly_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="30"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="61"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN60351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD63690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW28303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROU08342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="91" mass="9330" checksum="DDD364315CEA1418" modified="2016-02-17" version="1">MLGIIIWLIVGGIIGWIASMIMRTDGQQGVFLNIIVGIVGAFLGGWLGGVLGIGAGTINSGAFNIAGLALSLVGAIVLLGIVNLFRRGRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ13</accession>
    <name>A0A0S2DQ13_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">M61 family metallopeptidase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Peptidase, M61 (Glycyl aminopeptidase) family</fullName>
            <ecNumber evidence="4">3.4.11.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_25215</name>
        <name evidence="4" type="ORF">GLE_5208</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.11.-" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949635.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5208"/>
    <dbReference type="EnsemblBacteria" id="ALN60549">
        <property type="protein sequence ID" value="ALN60549"/>
        <property type="gene ID" value="GLE_5208"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5208"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5127"/>
    <dbReference type="OMA" id="DWDVNPY"/>
    <dbReference type="OrthoDB" id="679125at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024191">
        <property type="entry name" value="Peptidase_M61"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007963">
        <property type="entry name" value="Peptidase_M61_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040756">
        <property type="entry name" value="Peptidase_M61_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05299">
        <property type="entry name" value="Peptidase_M61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17899">
        <property type="entry name" value="Peptidase_M61_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016493">
        <property type="entry name" value="Glycyl_aminpptds"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242472" evidence="1">
        <location>
            <begin position="22"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M61_N" evidence="3">
        <location>
            <begin position="37"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M61" evidence="2">
        <location>
            <begin position="305"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW28459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="627" mass="69113" checksum="585B4F421E82A8B8" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ15</accession>
    <name>A0A0S2DQ15_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5351</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60692">
        <property type="protein sequence ID" value="ALN60692"/>
        <property type="gene ID" value="GLE_5351"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5351"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046116">
        <property type="entry name" value="DUF6053"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19523">
        <property type="entry name" value="DUF6053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="60" mass="6065" checksum="6860BCBE17219AF4" modified="2016-02-17" version="1">MGGPSGPTLLFQVAAIGSKSVGPEGPPTQPAGLAARTKKPGASRAFSFRFEPTAAINRPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQB0</accession>
    <name>A0A0S2DQB0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CAAX amino terminal protease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_5334</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5334"/>
    <dbReference type="EnsemblBacteria" id="ALN60675">
        <property type="protein sequence ID" value="ALN60675"/>
        <property type="gene ID" value="GLE_5334"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5334"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5251"/>
    <dbReference type="OMA" id="LLYYWRR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="194"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="303" mass="31166" checksum="ADC6C5835B16C5DC" modified="2016-02-17" version="1">MASGSTQAGSKQAGSRLARSSDVASAHADPAPGSPGPTPAIAAPPPANAAFAHRAAPPPPASLAPLLGAFAIDLLLALALLAGLSVLGTLGWGFAQGLRGLDGAQAAPGLTATMLIALSATAISALTVYYFRRNANAVERAASWRALWRPSSWGWIAIAPIVLVTCSTLIVAAAQAQGLDVTPTNQILGPAIRAQPALWLTFAVLIAPAYEELLFRRVLFGRLWAAGRPWLGLVLSSVAFALVHEPPGLGAGRGAGVLVLWTVYTLMGAVFAWIYRRSGSLWVPYLAHAGNNLLATLPLLAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQV7</accession>
    <name>A0A0S2DQV7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cysteine desulfurase</fullName>
            <ecNumber evidence="4">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">iscS</name>
        <name evidence="11" type="ORF">GLE_5484</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5484"/>
    <dbReference type="EnsemblBacteria" id="ALN60825">
        <property type="protein sequence ID" value="ALN60825"/>
        <property type="gene ID" value="GLE_5484"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5484"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5399"/>
    <dbReference type="OMA" id="YDHERIT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010240">
        <property type="entry name" value="Cys_deSase_IscS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601:SF34">
        <property type="entry name" value="PTHR11601:SF34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="10">
        <location>
            <begin position="2"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN60825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="184" mass="19459" checksum="6D64F0BBECCE5599" modified="2016-02-17" version="1">MSVSAHKIYGPKGIGALYVSPAARLRMRAQITGGGQQGGLRAGTLPTPLIVGFGEAARLMKEEGAAEVSRLAQLHARLWTQLVDQVGGVHLNGSADHRWVGNLNLRFDDVDADSLLLMVPQLAVSTGSACTAGTPEPSKVLRALGLSLEQASQSLRIGLGRMTTCDQIDRAVELIADAVRRLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-06-17" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA93</accession>
    <name>A0A0S2DA93_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0108</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55467">
        <property type="protein sequence ID" value="ALN55467"/>
        <property type="gene ID" value="GLE_0108"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0108"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.111"/>
    <dbReference type="OrthoDB" id="2133924at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="196" mass="22017" checksum="7923E99BDD4776DF" modified="2016-02-17" version="1">MEALVTTLEIQAYAPTDGAPRWQREPVWRDELIVVSDVVEVASKTQADIDRLVAQEQARYKATGNAEAIGKLNAQRGGDRFERKRVLALQQEHERAMTDAQSSNWSAQDVKRQRATSWSENKCARMLTAVQQAGSDLEKMLDALYAQQLPRRLGSKDAPVSDDINGRHPHPLPGGAYVYRVDYDPVPLGYREDLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAC3</accession>
    <name>A0A0S2DAC3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pkn5</name>
        <name evidence="8" type="ORF">GLE_0140</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945824.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="SMR" id="A0A0S2DAC3"/>
    <dbReference type="STRING" id="69.GLE_0140"/>
    <dbReference type="EnsemblBacteria" id="ALN55499">
        <property type="protein sequence ID" value="ALN55499"/>
        <property type="gene ID" value="GLE_0140"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0140"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.142"/>
    <dbReference type="OMA" id="HERYVAN"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="77"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN55499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="940" mass="103939" checksum="E4829A7B07AC571E" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAC6</accession>
    <name>A0A0S2DAC6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ADP-ribosyl-[dinitrogen reductase] glycohydrolase</fullName>
            <ecNumber evidence="1">3.2.2.24</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="2">ADP-ribosylglycohydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">draG</name>
        <name evidence="2" type="ORF">FE772_01580</name>
        <name evidence="1" type="ORF">GLE_0134</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.2.24" evidence="1"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945820.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0134"/>
    <dbReference type="EnsemblBacteria" id="ALN55493">
        <property type="protein sequence ID" value="ALN55493"/>
        <property type="gene ID" value="GLE_0134"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0134"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.137"/>
    <dbReference type="OMA" id="HERIYHE"/>
    <dbReference type="OrthoDB" id="1661477at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047407">
        <property type="term" value="F:ADP-ribosyl-[dinitrogen reductase] hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005502">
        <property type="entry name" value="Ribosyl_crysJ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036705">
        <property type="entry name" value="Ribosyl_crysJ1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03747">
        <property type="entry name" value="ADP_ribosyl_GH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101478">
        <property type="entry name" value="SSF101478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="280" mass="30004" checksum="45DDC1E56971D953" modified="2016-02-17" version="1">MLLELAIGDAYGAGFEYAADRIVRERNDGAHYVRHPRHAIEPGCYTDDTQMSLAIAEALAEGDPWTRESLAERFVAAFKRDPREGYASRFHGLLTEVRDGADLLARIVPDSAKSGAAMRAPPIGALADTAEVVRRAELQARITHDTPDGVAAAVAAALCTHYFVHRRGAKDGLAGYLAAHVPGPWREPWRGKVGALGMDSVHAAVAAVLAHSRMSELLRACIAYTGDVDTVATIALAAGACSEEIAQDLPASLYDGLENGRYGREYLIALDARLMALATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAS9</accession>
    <name>A0A0S2DAS9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">AmpG family muropeptide MFS transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Major facilitator superfamily MFS_1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FE772_02120</name>
        <name evidence="6" type="ORF">GLE_0260</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945910.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0260"/>
    <dbReference type="EnsemblBacteria" id="ALN55619">
        <property type="protein sequence ID" value="ALN55619"/>
        <property type="gene ID" value="GLE_0260"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0260"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.261"/>
    <dbReference type="OMA" id="ANPFYVD"/>
    <dbReference type="OrthoDB" id="1165704at2"/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Feng T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
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        <property type="protein sequence ID" value="OPD62610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="NZ_MTAY01000047.1"/>
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    <dbReference type="EnsemblBacteria" id="ALN55807">
        <property type="protein sequence ID" value="ALN55807"/>
        <property type="gene ID" value="GLE_0449"/>
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        <property type="protein sequence ID" value="OPD62610"/>
        <property type="gene ID" value="BV903_17570"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0449"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.447"/>
    <dbReference type="OMA" id="ESQDKDH"/>
    <dbReference type="OrthoDB" id="1153621at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036624">
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    <dbReference type="Pfam" id="PF05638">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD62610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="177" mass="19344" checksum="B1974A3DB520E208" modified="2016-02-17" version="1">MSNGNQELKQKPSIFLKIGPFKGESRDNDHKDWIELLDFHFEVVQPRSATGSSTGGHTAARSEISTINIVKEADLSSTAFLQAAANGSTLDKMTVNVRRADGKDGKAINYRVFEAMNIVVSKVRTYVGSNGLLMEDIQLSIATMKDTYTAQGIEGGPKGNSTFQYSWSKNTPQYTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBL4</accession>
    <name>A0A0S2DBL4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_03540</name>
        <name evidence="2" type="ORF">GLE_0564</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0564"/>
    <dbReference type="EnsemblBacteria" id="ALN55922">
        <property type="protein sequence ID" value="ALN55922"/>
        <property type="gene ID" value="GLE_0564"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0564"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.558"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="SSF48613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="274"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="433" mass="47552" checksum="604B2704B5CA9B25" modified="2016-02-17" version="1">MNTASASNASAPPAPSPSRHDLHAFWTLADDLQRQTVDHAGALFAFVETASPPRLFSLLAQYRSFTDYYIADIALLIARLPPGRMRSFLADILFDELGSGDATQAHPQLYDDFLASLRIEHAPHDRLPLAANLALLDAARAALVAPGASAAYGVGLRGMGGECVCQVYLARLHEHLVRNPYIREHHDRIDWIFWELHVGEHDIAHREKLRALIGEQIGGMDAGSVAELERGYRDSMAAWQSFWSHIHAAATAPDPRAHARGPGDCAGAGDAPIAQFHLAIGVHDLQQARAFYCDVLGAKQGRSTRNLVDLDFYGHHLVIHQAPRESTGENAFGSAFYGETVKVPHFGMNLNWRDWSALAERIKSRGYGFIDPPHVRMRDLPGEHATMFLADPSGNALEFKAFRNHAEVFATIFSPHTRDTDSLDGLVKKAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBR9</accession>
    <name>A0A0S2DBR9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2 3">FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_03765</name>
        <name evidence="2" type="ORF">GLE_0612</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946162.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55970">
        <property type="protein sequence ID" value="ALN55970"/>
        <property type="gene ID" value="GLE_0612"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0612"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.604"/>
    <dbReference type="OrthoDB" id="948949at1224"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="1">
        <location>
            <begin position="53"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="550" mass="59764" checksum="9CA1C04197E14296" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBS1</accession>
    <name>A0A0S2DBS1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GTP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BV903_15665</name>
        <name evidence="6" type="ORF">FE772_03755</name>
        <name evidence="4" type="ORF">GLE_0610</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">C3</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000040">
        <property type="protein sequence ID" value="OPD63066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946161.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0610"/>
    <dbReference type="EnsemblBacteria" id="ALN55968">
        <property type="protein sequence ID" value="ALN55968"/>
        <property type="gene ID" value="GLE_0610"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63066">
        <property type="protein sequence ID" value="OPD63066"/>
        <property type="gene ID" value="BV903_15665"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0610"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.602"/>
    <dbReference type="OMA" id="GVDDNYG"/>
    <dbReference type="OrthoDB" id="1438064at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN55968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD63066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW24915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="182" mass="19631" checksum="A7849BFA69FE35FD" modified="2016-02-17" version="1">MNDLIKLAFVGNMGAGKTTAIRAISDGEPISTEMPISHAGEGGKTHTTVAMDYATIELDDGELLHVYGVPGQRYLDFMWPLVCEGAVGIVVLVAADDPDMIGQADALLREFARIAPAASFAVGVTRADLSDDFALLQLRDALGRRGHRLPMARLDARDSAQVETLIRMLLSYRYAESRINAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBU0</accession>
    <name>A0A0S2DBU0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-oxoadipate enol-lactonase</fullName>
            <ecNumber evidence="2">3.1.1.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pcaD</name>
        <name evidence="3" type="ORF">FE772_03955</name>
        <name evidence="2" type="ORF">GLE_0651</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.24" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0651"/>
    <dbReference type="EnsemblBacteria" id="ALN56009">
        <property type="protein sequence ID" value="ALN56009"/>
        <property type="gene ID" value="GLE_0651"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0651"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.640"/>
    <dbReference type="OMA" id="AYAACCD"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047570">
        <property type="term" value="F:3-oxoadipate enol-lactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042952">
        <property type="term" value="P:beta-ketoadipate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026968">
        <property type="entry name" value="PcaD/CatD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02427">
        <property type="entry name" value="protocat_pcaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="42"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="280" mass="29889" checksum="18183A696121F135" modified="2016-02-17" version="1">MSIVAAVPNPVPNPVPNNVSGHVVAGDGTRIAYRFDGDSERPVLVLSNSIATDLHMWDAQIPALSARFRVLRYDARGHGGSDAPAGAYSLDRLGRDVLELLDALGLERVHFLGLSLGGFVGQWLAIHAPQRIDRLVLSNTSAHLGPAAAFDERIREALAAPDMSAIAARFLRDWFPPAMLDSADPRIEPFRDALLAMRATGLAGSFAAVRDADLRRTAASIAAPTLVIAGRSDPVTLAEHGRVLAETVPGARFLLLPAVHMANIECADAFERAVIEFLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBZ6</accession>
    <name>A0A0S2DBZ6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0625</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0625"/>
    <dbReference type="EnsemblBacteria" id="ALN55983">
        <property type="protein sequence ID" value="ALN55983"/>
        <property type="gene ID" value="GLE_0625"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0625"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.616"/>
    <dbReference type="OMA" id="VPGQTRY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594818" evidence="2">
        <location>
            <begin position="24"/>
            <end position="1258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1258" mass="139983" checksum="0C49FF40F092A899" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC05</accession>
    <name>A0A0S2DC05_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Efflux ABC transporter, permease protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="11">FtsX-like permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FE772_04165</name>
        <name evidence="10" type="ORF">GLE_0697</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946225.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0697"/>
    <dbReference type="EnsemblBacteria" id="ALN56055">
        <property type="protein sequence ID" value="ALN56055"/>
        <property type="gene ID" value="GLE_0697"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0697"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.685"/>
    <dbReference type="OMA" id="MFNIERR"/>
    <dbReference type="OrthoDB" id="768211at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="284"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="372"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="9">
        <location>
            <begin position="59"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="315"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN56055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW24987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="408" mass="44560" checksum="61B25C2C3828BDEC" modified="2016-02-17" version="1">MDIRPILTTLRRHKTAAALIVFEVALTCAIICNALFLIQTRIARLDRPSGMAEKELLALRISDISNGNETDALTRSDLAALRAIPGVRSATISNQVRYGDSAWNSGIGPKPSQQVETASVTTFFGDAQLLDTLGAKLVAGRNFSEDEIVDFNQRIKPDAPPIPVAIVTKALADKLFPGQDPLGRPFYNGGTDGIRIIGVIEHLLRPNELTGPAAADYSVIFPSRVDYNNGFYLIRVNDPAQRKQVLEAVGRTLSKNGSQRILDKDYGVLEEMADKFHRTDRSMVWLLGAVCVALLIVTALGIVGLASFWVQQRTKQIGVRRALGATRGQILRYFQTENFLLTGIGIVLGMVIAFAINLLLMKYYELPRLPVLYLPLGALSLWLLGQLAVYGPARRAAMVPPALATRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC56</accession>
    <name>A0A0S2DC56_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5 7">Bacterioferritin</fullName>
            <ecNumber evidence="5">1.16.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">bfr</name>
        <name evidence="10" type="ORF">BV903_22480</name>
        <name evidence="12" type="ORF">D9T17_23535</name>
        <name evidence="11" type="ORF">FE772_04310</name>
        <name evidence="9" type="ORF">GLE_0723</name>
    </gene>
    <organism evidence="9 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 13">C3</strain>
        </source>
    </reference>
    <reference evidence="10 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">OH11</strain>
        </source>
    </reference>
    <reference evidence="11 16" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 16">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>4 Fe(2+) + 4 H(+) + O2 = 4 Fe(3+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11148"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.16.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 7">Belongs to the bacterioferritin family.</text>
    </comment>
    <dbReference type="EC" id="1.16.3.1" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000075">
        <property type="protein sequence ID" value="OPD61668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="5 6 7" id="KW-0479">Metal-binding</keyword>
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            <begin position="1"/>
            <end position="145"/>
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        <ligand>
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            <label>1</label>
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        </location>
        <ligand>
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            <note>ligand shared between dimeric partners</note>
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        <ligandPart>
            <name>Fe</name>
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        </ligandPart>
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            <position position="54"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
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        </location>
        <ligand>
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            <label>2</label>
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        </location>
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        <location>
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            <dbReference type="ChEBI" id="CHEBI:24875"/>
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        <source>
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        <source>
            <dbReference type="EMBL" id="ROU04528.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
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    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
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    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="158" mass="18352" checksum="94FD191D8B726736" modified="2016-02-17" version="1">MKGDAKVIEYLNKALYNELTAINQYFLHAKMLKNWGLKELAEHEYHESIDEMKHADKLSDRILFLDGLPNFQALGKLRIGENPRELLECDLALELEAIPLLREAIKYCETVSDYVSRKLFADILDSEEEHVDWIETQLALIERIGEQNYLLTKIEDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC90</accession>
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        </recommendedName>
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        <name type="scientific">Lysobacter enzymogenes</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
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                <person name="Feng T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="match status" value="1"/>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="195" mass="21299" checksum="29690248AFE2DFEB" modified="2016-02-17" version="1">MSKALPDDALDQLFRSARTHNVLGGEISDETLRQLYDLTKWGPTSANGSPARFVFVKSPQAKEKLRPALSEGNLAKTMAAPVTVIVAHDLEFYEKLPYLFPHDDARSWFAGNDAAINVTAFRNGSLQGAYLILAARSLGLDTGAMSGFDNAKVDEAFFAGTKIKSNFLINLGHGDHDKLFPRSPRLPFDEAACIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCB9</accession>
    <name>A0A0S2DCB9_LYSEN</name>
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        <submittedName>
            <fullName evidence="4">O-Antigen Polymerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_0800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0800"/>
    <dbReference type="EnsemblBacteria" id="ALN56158">
        <property type="protein sequence ID" value="ALN56158"/>
        <property type="gene ID" value="GLE_0800"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0800"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.789"/>
    <dbReference type="OMA" id="LAYVAMW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007016">
        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04932">
        <property type="entry name" value="Wzy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="40"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="231"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="382"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="434"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="458" mass="48119" checksum="031375E3073D2FCA" modified="2016-02-17" version="1">MPKPAAPSPGAPASFAADAAGAMRAPPPQEIVGWRWAPAWVLAYVALLFAPGFAETVLSLGALTMLVKLTLGRMRTGPRLLSDAAWALTSALFAAYWLPELVSAIDAVDPARALREAAVDLRYLPFLWLVAAAVASRRGRNITFGGLAAILALWIADALLQGLSGGIESPLFRAIDAAKQAISGHGMCTASELAVVDRLGGVLGPCNLKLGQVIASFSPFLLYAAGRRFGLAGWLTATALTGIVVVLAGSRASWITFALVLLLSGWRLLGWKKLLALFACGLLALVVLDRSSSQVHERLVRTAHIVSADVAGLDDALSGRARIWRAAGCMIAAHPLNGVGARGFREAFPGCDPMPGVTTSWGDGPALHAHQLLLEVLSETGAFGLLLWLAGAALAWRAWAFADAQARERARPAMVALAVTVFPLNTHLAFYSTFWGGLTLLLAALYAGSLLAQPRSEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCV5</accession>
    <name>A0A0S2DCV5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AAA family ATPase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Methanol dehydrogenase regulatory protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">MoxR family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_12315</name>
        <name evidence="4" type="ORF">FE772_05325</name>
        <name evidence="2" type="ORF">GLE_0937</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000030">
        <property type="protein sequence ID" value="OPD63604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946408.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000030.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0937"/>
    <dbReference type="EnsemblBacteria" id="ALN56295">
        <property type="protein sequence ID" value="ALN56295"/>
        <property type="gene ID" value="GLE_0937"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63604">
        <property type="protein sequence ID" value="OPD63604"/>
        <property type="gene ID" value="BV903_12315"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0937"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.925"/>
    <dbReference type="OMA" id="SRAWAWL"/>
    <dbReference type="OrthoDB" id="688156at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="54"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="342" mass="37350" checksum="CC01E850300E3629" modified="2016-02-17" version="1">MDSATDHAQTPVAATSPADVARLHDAFRQLRDALAVEIVGQSELIERLLIALLADGHLLVEGAPGLAKTSAVRALAARLEADFARVQFTPDLLPADLTGTEVWRPQEGRFEFQAGPIFHPILLADEINRAPAKVQSALLEAMGERQVTVGRATYALPPLFLVMATQNPIEQEGTFPLPEAQLDRFLMHVRIGYPEAAAEAEILRLARERARQTLKPAPVAVQRMPLADVFAARSAVLDLHVAPAVERYLVELVLASRDAARYDATLARRIAWGASPRGSIALERCARAHAWLAGRDFVTPDDVRAIAPDVLRHRILPSYEATAEGWDGDRLLGELLKKVPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD21</accession>
    <name>A0A0S2DD21_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HOASN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0890"/>
    <dbReference type="EnsemblBacteria" id="ALN56248">
        <property type="protein sequence ID" value="ALN56248"/>
        <property type="gene ID" value="GLE_0890"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0890"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.879"/>
    <dbReference type="OMA" id="RDAHHEY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1240.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029474">
        <property type="entry name" value="HOASN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037061">
        <property type="entry name" value="Lytic_TGlycoase_superhlx_L_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039068">
        <property type="entry name" value="PqqC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40279">
        <property type="entry name" value="PTHR40279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14515">
        <property type="entry name" value="HOASN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="SSF48613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HOASN" evidence="1">
        <location>
            <begin position="12"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="335" mass="38201" checksum="4E6ADE1C8797BEB1" modified="2016-02-17" version="1">MNATMPASVAPNHSLPQLDSLQSNRARILARALHPEAPYAHLQTAGKTLSELAESALKGDRDAHHEYQKLLYILSLSDDTGTALTRRWLSNEGYRVEERHIPAADVPHALSEAEFLARIEQEVAARSREKHPMSEYIFEGRASRAQLQVFLRRQWFRTFRLYRDAADLLVNLVDVDEAAALGRYLYGELGEESEQGSHPRLLAKLLRAIGLDADFQAVSTLPEEIAYLNNRVRSFRNPDVGWGLAVFYITEIVVPGNHEKLYKALLKAGLSEDEAEYYRIHVSLVPPRAKREWSLIAKRLPDHAFQKSFLTSLAQHFRVERAYYDAVWDEMRAVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDF1</accession>
    <name>A0A0S2DDF1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56538">
        <property type="protein sequence ID" value="ALN56538"/>
        <property type="gene ID" value="GLE_1180"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1180"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1165"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="130" mass="13982" checksum="0F3C2BEAF164BD88" modified="2016-02-17" version="1">MRWPLEGEAGKQKVAAALRRSFFMKPLQARQFSGEGPVKLADGNVLSSAWIGELSGQIDIGVAAEPCVSPELAAGWIGARGEATLDAHGVDRGKTYQAQGAGVRVEFTTTPSTYRCIDSINIYPFDDPRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDF3</accession>
    <name>A0A0S2DDF3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_06600</name>
        <name evidence="3" type="ORF">GLE_1217</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946606.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1217"/>
    <dbReference type="EnsemblBacteria" id="ALN56574">
        <property type="protein sequence ID" value="ALN56574"/>
        <property type="gene ID" value="GLE_1217"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1217"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1202"/>
    <dbReference type="OMA" id="DADHLRM"/>
    <dbReference type="OrthoDB" id="1976167at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="115"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="154" mass="15944" checksum="C5971A92FAF5220E" modified="2016-02-17" version="1">MNDPLPTAAPTPAPNAAPASASASKDADQLDLIGILYYVLAAFAALFSLFPLLHVGMGIAMLTGAFDQPGNPNPPPAAVGWVFVIFGAGFILCGLAFAALLVLGGRRMRQRRSHTLCAVVAGVSCMFMPFGTILGVFALVLLLKPETKALFGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDL2</accession>
    <name>A0A0S2DDL2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Translocator protein, LysE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_1277</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946651.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1277"/>
    <dbReference type="EnsemblBacteria" id="ALN56634">
        <property type="protein sequence ID" value="ALN56634"/>
        <property type="gene ID" value="GLE_1277"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1277"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1260"/>
    <dbReference type="OMA" id="SIHFVIA"/>
    <dbReference type="OrthoDB" id="1927576at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006324">
        <property type="entry name" value="LeuE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="150"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN56634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="210" mass="21962" checksum="6AC3BC5EA5E8A63F" modified="2016-02-17" version="1">MFDASTLAAYLIAAAVLVFIPGPGTAWIVAQSAAGGTARGIQAAFGLETATLIHALAAGLGLSALLATSALAFEVLKYAGAAYLIWLGIKAWRGGPATAAPAADAPPPARISARQVYWRSVMTGVLNPKVALFFLAFLPQFVHPERGMVWLQFLVLGALLSLIGLSNSLILSFAVGRFGRRFGGGGGRWKERLTGSVFIALGLRLAVQQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE07</accession>
    <name>A0A0S2DE07_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Phosphoenolpyruvate-protein phosphotransferase</fullName>
            <ecNumber evidence="5 13">2.7.3.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Phosphotransferase system, enzyme I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="primary">ptsP</name>
        <name evidence="21" type="ORF">FE772_06435</name>
        <name evidence="20" type="ORF">GLE_1183</name>
    </gene>
    <organism evidence="20 22">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="20 22" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 22">C3</strain>
        </source>
    </reference>
    <reference evidence="21 23" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 23">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl-[protein] + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:23880"/>
            <dbReference type="Rhea" id="RHEA-COMP:9745"/>
            <dbReference type="Rhea" id="RHEA-COMP:9746"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:64837"/>
            <dbReference type="EC" id="2.7.3.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 13 16">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.7.3.9" evidence="5 13"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946578.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1183"/>
    <dbReference type="EnsemblBacteria" id="ALN56541">
        <property type="protein sequence ID" value="ALN56541"/>
        <property type="gene ID" value="GLE_1183"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1183"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1168"/>
    <dbReference type="OMA" id="CNAEWAL"/>
    <dbReference type="OrthoDB" id="467393at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008965">
        <property type="term" value="F:phosphoenolpyruvate-protein phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024692">
        <property type="entry name" value="PTS_EI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006318">
        <property type="entry name" value="PTS_EI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008731">
        <property type="entry name" value="PTS_EIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036618">
        <property type="entry name" value="PtsI_HPr-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05524">
        <property type="entry name" value="PEP-utilisers_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000732">
        <property type="entry name" value="PTS_enzyme_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47831">
        <property type="entry name" value="SSF47831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01417">
        <property type="entry name" value="PTS_I_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="13 16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 13 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 13" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="21" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="13 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 13" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PEP-utilisers_N" evidence="19">
        <location>
            <begin position="6"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="17">
        <location>
            <begin position="155"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers_C" evidence="18">
        <location>
            <begin position="252"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="PEP binding" evidence="15">
        <location>
            <begin position="456"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="14">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="14">
        <location>
            <position position="504"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="433"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="457"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="467"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR000732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF05524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ALN56541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="QCW25352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="569" mass="62209" checksum="C97D18EA94F4BEC9" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE21</accession>
    <name>A0A0S2DE21_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56607">
        <property type="protein sequence ID" value="ALN56607"/>
        <property type="gene ID" value="GLE_1250"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1250"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1234"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="54" mass="6297" checksum="DAE854F7ABA0B459" modified="2016-02-17" version="1">MDGWLDDDNYMMFLWKFGDSSPRYVALAITNDFLPSTHERALVGYFELVPSARH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEQ3</accession>
    <name>A0A0S2DEQ3_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1777</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="66" mass="6985" checksum="0D8824B67774272A" modified="2016-02-17" version="1">MERRTYGICHLKLATGWGRAPDSTRGQVAEGATGVKGAAARGSCGRGFSPDALVPDRRDLSARRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEQ7</accession>
    <name>A0A0S2DEQ7_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">Feruloyl-CoA synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1645</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1645"/>
    <dbReference type="EnsemblBacteria" id="ALN57002">
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        <property type="gene ID" value="GLE_1645"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1645"/>
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    <dbReference type="OMA" id="LGCITHG"/>
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        <property type="component" value="Chromosome"/>
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    </dbReference>
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    </dbReference>
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    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="79"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="520"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="615" mass="67462" checksum="8BDE2FD1FB6BD89F" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEZ2</accession>
    <name>A0A0S2DEZ2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_08940</name>
        <name evidence="3" type="ORF">GLE_1734</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
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    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW25773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947013.1">
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57089">
        <property type="protein sequence ID" value="ALN57089"/>
        <property type="gene ID" value="GLE_1734"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1734"/>
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    <dbReference type="OrthoDB" id="2120597at2"/>
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    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726648" evidence="2">
        <location>
            <begin position="23"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="191" mass="20299" checksum="5FC31DA11E97D61C" modified="2016-02-17" version="1">MHRIASFAFSLALALAATPSLAAPAPAAAAQAAVETVGVYSNVRVSGGEDPHAEGYDVELYRENGVLFGLFYSSQGMVGDTPRGRLQDVRYDAASGKLSFRAKLTIGQEFSKDSGPDGRPSRDLFEFDGTLGAKTLSGALLHRSGYAPSEAGERQMVTLKRDAQRSRDAGELAPASRAQWLAEPVPNGPQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF43</accession>
    <name>A0A0S2DF43_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1768</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57122">
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        <property type="gene ID" value="GLE_1768"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1768"/>
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    <dbReference type="OMA" id="GHSTERT"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594930" evidence="1">
        <location>
            <begin position="32"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="158" mass="16830" checksum="01FE211F066E525F" modified="2016-02-17" version="1">MSSFATSRPASPRLLLPLAAALLLGAGAAHAQSDNEVYESAIAKASRLCPGHSKERTTPGVRAVPVGALRVLAQRNYTMCPDRRLDAATPAVWYGQVGVFAWNPEVQGAAQLIAKQVDAMTRKEEFPAETLVWKADGSAATGTVVPMFEPRPRPVGSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF81</accession>
    <name>A0A0S2DF81_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Malonyl CoA-acyl carrier protein transacylase</fullName>
            <ecNumber evidence="3">2.3.1.39</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1885</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.39" evidence="3"/>
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        <property type="protein sequence ID" value="ALN57237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947120.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1885"/>
    <dbReference type="EnsemblBacteria" id="ALN57237">
        <property type="protein sequence ID" value="ALN57237"/>
        <property type="gene ID" value="GLE_1885"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1885"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1855"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004314">
        <property type="term" value="F:[acyl-carrier-protein] S-malonyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
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        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_AT" evidence="2">
        <location>
            <begin position="2"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="630" mass="65196" checksum="9B3806255A9162A5" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFA4</accession>
    <name>A0A0S2DFA4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase, families S8 and S53</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_1749</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
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            <authorList>
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    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594770" evidence="3">
        <location>
            <begin position="17"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="212"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="335"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="4">
        <location>
            <begin position="464"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="387"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="601" mass="66511" checksum="63DECF8529E10EB4" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFX2</accession>
    <name>A0A0S2DFX2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1856</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57208">
        <property type="protein sequence ID" value="ALN57208"/>
        <property type="gene ID" value="GLE_1856"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1856"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1827"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="79" mass="8691" checksum="569D69714D3A1651" modified="2016-02-17" version="1">MPVDAFKALSAFQQELHGIVRTLQPEVLIEIGYPAGQDHRLLREVFQALARRLDPVMDACVWSPVGDDGAGPGASRRLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFZ3</accession>
    <name>A0A0S2DFZ3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">YhhN-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_2134</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM86 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947304.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2134"/>
    <dbReference type="EnsemblBacteria" id="ALN57484">
        <property type="protein sequence ID" value="ALN57484"/>
        <property type="gene ID" value="GLE_2134"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2134"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2098"/>
    <dbReference type="OMA" id="ACFKCLP"/>
    <dbReference type="OrthoDB" id="1768508at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012506">
        <property type="entry name" value="YhhN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31885">
        <property type="entry name" value="PTHR31885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07947">
        <property type="entry name" value="YhhN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="226" mass="23554" checksum="1BD3BD5497B862F2" modified="2016-02-17" version="1">MSERGIEQARGWGAVVALSAALAIVGAYAGGAAIWLHYAFKPSTTLLIAAMVWRLGAGAGADAGYRRAIFAGLLLSTAGDVFLMLPGDWFVFGLASFLCAHVAYLAGLCRRARPFAAAWPFLAYAILAGAVLAVLWPHLPGELRIPVVVYVAVLAAMAAQAAAVWRRRADAAGVAAAIGGACFVFSDATLAIDRFAAPFAAAQALVLASYWAAQWWIGRSATLARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG31</accession>
    <name>A0A0S2DG31_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcription termination/antitermination protein NusA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">nusA</name>
        <name evidence="10" type="ORF">BV903_08685</name>
        <name evidence="12" type="ORF">D9T17_13345</name>
        <name evidence="11" type="ORF">FE772_10975</name>
        <name evidence="9" type="ORF">GLE_2175</name>
    </gene>
    <organism evidence="9 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 13">C3</strain>
        </source>
    </reference>
    <reference evidence="10 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">OH11</strain>
        </source>
    </reference>
    <reference evidence="11 16" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 16">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Participates in both transcription termination and antitermination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NusA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000018">
        <property type="protein sequence ID" value="OPD64367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000033">
        <property type="protein sequence ID" value="ROU06435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947338.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2175"/>
    <dbReference type="EnsemblBacteria" id="ALN57524">
        <property type="protein sequence ID" value="ALN57524"/>
        <property type="gene ID" value="GLE_2175"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64367">
        <property type="protein sequence ID" value="OPD64367"/>
        <property type="gene ID" value="BV903_08685"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2175"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2137"/>
    <dbReference type="OMA" id="MDIDMSA"/>
    <dbReference type="OrthoDB" id="384865at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1480.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00945_B">
        <property type="entry name" value="NusA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010995">
        <property type="entry name" value="DNA_repair_Rad51/TF_NusA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025249">
        <property type="entry name" value="KH_dom_NusA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030842">
        <property type="entry name" value="NusA_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036555">
        <property type="entry name" value="NusA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013735">
        <property type="entry name" value="TF_NusA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010214">
        <property type="entry name" value="Tscrpt_termin_fac_NusA_C_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010213">
        <property type="entry name" value="Tscrpt_termination_fac_NusA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22648">
        <property type="entry name" value="PTHR22648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13184">
        <property type="entry name" value="KH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08529">
        <property type="entry name" value="NusA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47794">
        <property type="entry name" value="SSF47794"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69705">
        <property type="entry name" value="SSF69705"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01953">
        <property type="entry name" value="NusA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01954">
        <property type="entry name" value="nusA_Cterm_rpt"/>
        <property type="match status" value="2"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="6 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="5 7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 7" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="S1 motif" evidence="8">
        <location>
            <begin position="139"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN57524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD64367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW26116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROU06435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="495" mass="54591" checksum="7F788358CF34659C" modified="2016-02-17" version="1">MSKELLLVVDAVANEKGVPREVIFEAIEAALASAAKKRYHDEDVLVRVSIDQKDGSYETFRRMEVVADDVVMESPDRQIRLMDAVDEVEGVEVGDYIEEQIENPEFGRIAAQAAKQVIVQRVREAERAQVVDAWKDRVGELVTGIVKRVERGNIYVDLGGNSEAIIPKDKGIPRDVLRAGDRVRGYLFDVRTEPRGPQLFISRAAPEFMMELFKLEVPEVGQGLVSIKACARDPGDRAKIAVLAHDNRTDPIGACIGMRGSRVQAVSNELNGERVDIVLWSDNPAQFVINAMAPAEVQSIIVDEEKHSMDLAVAEERLAQAIGKGGQNVRLASRLSGWQLNVMTQDQVTAKSEAEQNAARQLFQDKLEVDEEIAGILVSEGFSTVEEIAYVPVGELLAVEGFDEDIVEELRARARDALLNEALAAEEELDEHQPAADLLELAGMDEALAFTLASRGVVSRDDLADLATDELTDIEGVDEERAAALIMEARKHWFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGB8</accession>
    <name>A0A0S2DGB8_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2189</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57538">
        <property type="protein sequence ID" value="ALN57538"/>
        <property type="gene ID" value="GLE_2189"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2189"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2151"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="131" mass="14106" checksum="5B294581DBC2A34C" modified="2016-02-17" version="1">MPTLTAATQGPMKPRTAVRRPADRPGIVVSAETGDNAGTARPTAAQLKKRARKNARAEAHRPGPCVVSLRRRRPSWRLPAEGGLSRSLAARPGAANRTCQNPQRPRRAAGRARCAGSALMIRDHRRPPAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGH1</accession>
    <name>A0A0S2DGH1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_08740</name>
        <name evidence="5" type="ORF">FE772_11030</name>
        <name evidence="3" type="ORF">GLE_2187</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000018">
        <property type="protein sequence ID" value="OPD64377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947349.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000018.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57536">
        <property type="protein sequence ID" value="ALN57536"/>
        <property type="gene ID" value="GLE_2187"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64377">
        <property type="protein sequence ID" value="OPD64377"/>
        <property type="gene ID" value="BV903_08740"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2187"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2149"/>
    <dbReference type="OrthoDB" id="2046305at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594998" evidence="2">
        <location>
            <begin position="25"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD64377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="164" mass="17626" checksum="FA8104DE52AAB255" modified="2016-02-17" version="1">MNASLGRILIVAAGAAILASSALAMTVIGGPGDQRLARMDLRRTHDLQRIESEIERYAERHGRLPADLAELAAQPGVALGVADPQTAMPYRYLPGAAGRYRLCAGFDTDSGQRDAARRSDSEVDDEWRHPRGEFCFDGDASDSMEEGDASDSVEESDASDATQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGK7</accession>
    <name>A0A0S2DGK7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947347.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57533">
        <property type="protein sequence ID" value="ALN57533"/>
        <property type="gene ID" value="GLE_2184"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2184"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2146"/>
    <dbReference type="OMA" id="SERAYHF"/>
    <dbReference type="OrthoDB" id="1705862at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018715">
        <property type="entry name" value="DUF2239"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09998">
        <property type="entry name" value="DUF2239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="215" mass="22661" checksum="734B354E0DA2D178" modified="2016-02-17" version="1">MTTSTAPGYTAFAGQRLLARGRLADVAVAVHAAAARASAAELLVFDDRTGQQIDLHLGGDAQAVAERYRERPDAADAAPDDDAPQPGPAQREPAQRGRGRPRLGVTAREVTLLPRHWDWLAAQPGGASVTLRKLIDQARKQGEAGMRQRLAREAAYRCLNALAGNAPGAEDATRALFAGDAAGFARRLDAWPADVRAYLLALSADAFAASEAATT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGL2</accession>
    <name>A0A0S2DGL2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_11805</name>
        <name evidence="2" type="ORF">GLE_2358</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947476.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57707">
        <property type="protein sequence ID" value="ALN57707"/>
        <property type="gene ID" value="GLE_2358"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2358"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2319"/>
    <dbReference type="OrthoDB" id="1784317at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="121" mass="13786" checksum="ED75549079436F4C" modified="2016-02-17" version="1">MRLESLQTAGQRRSAAVAPLAGAPSPMSPDAVDLDSELSYWRANYRLLFGRPGLRFSDYEPAVKLGLDAYVRGQVEDWPELDEQLRDRYRRVHGASRLDWNDARAVAVAACERIQRERGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGS3</accession>
    <name>A0A0S2DGS3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF1501 domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Tat (Twin-arginine translocation) pathway signal sequence protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_11065</name>
        <name evidence="3" type="ORF">GLE_2195</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947355.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2195"/>
    <dbReference type="EnsemblBacteria" id="ALN57544">
        <property type="protein sequence ID" value="ALN57544"/>
        <property type="gene ID" value="GLE_2195"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2195"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2157"/>
    <dbReference type="OMA" id="VASHEHI"/>
    <dbReference type="OrthoDB" id="663130at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10518">
        <property type="entry name" value="TAT_signal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726805" evidence="2">
        <location>
            <begin position="34"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="481" mass="50227" checksum="8666C575F0115DF1" modified="2016-02-17" version="1">MTTRRDFLKGTCATAAATAVAGPSLLFANPALAAANGHDTVVHLFLRGGLDGLNLVVPIDGADRTFYEQARPNLAIAATGAYGALPLTLASGGGTGFGLHPSASGLRDLWVSGRMAIVHACGLLTSVTRSHFDAQLYIDLGTPGAQGIGSGWMARAMNTQPGLDGSERVPALGVAARQPAGLLSSVQALTMASPSDFALNAGAWSWQMARAGAPTGFRGVNETLSDLWGRTSPLELGGQRADRALQVIATQSYSALPAGWPTGTFAQQLWTIAQSIQFDLGLRYATLDLGGWDTHDGQGTAGSGYHYYQNKIAELSQALSAFHAALEASGHAGRVTVVVQSEFGRRVRANANGGTDHGYGNPVLVLGGAVNGRRFYGSWSGLDPEILSPHFGDVPVTTDHRQVLSELLVKRMGNSNLATVFPGYSGYAPMGIVRDVGALAPAPKPAPGARRFGAAPVTAPATAQEPDLMQRLMRYVQELVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH67</accession>
    <name>A0A0S2DH67_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_2593</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947662.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2593"/>
    <dbReference type="EnsemblBacteria" id="ALN57941">
        <property type="protein sequence ID" value="ALN57941"/>
        <property type="gene ID" value="GLE_2593"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2593"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2552"/>
    <dbReference type="OMA" id="QFKSHNA"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045812">
        <property type="entry name" value="DAHL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19443">
        <property type="entry name" value="DAHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="454"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="802" mass="86810" checksum="915DAD97D2B0C8F1" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH86</accession>
    <name>A0A0S2DH86_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FMN-binding negative transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Transcriptional regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_13325</name>
        <name evidence="1" type="ORF">GLE_2659</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947711.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2659"/>
    <dbReference type="EnsemblBacteria" id="ALN58007">
        <property type="protein sequence ID" value="ALN58007"/>
        <property type="gene ID" value="GLE_2659"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2659"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2618"/>
    <dbReference type="OMA" id="ARANPQW"/>
    <dbReference type="OrthoDB" id="1804797at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007396">
        <property type="entry name" value="TR_PAI2-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35802">
        <property type="entry name" value="PTHR35802"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04299">
        <property type="entry name" value="FMN_bind_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010372">
        <property type="entry name" value="PaiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="211" mass="23866" checksum="EBD3EC5BE500206E" modified="2016-02-17" version="1">MYLPRAFDETDLGALDRLAAADAFATLVTVRGDAPQVSHLPVLYARERERIELRGHWARPNPQARHAGAALAILHGPHAYISPGWYPDKETAARVPTWNYAVAHLHGQLHTFDDEAALAALVDELSVRHEARVGGDWRFESERDELRRQLRGIVGFRFAVERIELKFKLSQNHPLANRENVAARLQAQDREDSRAVAALMRERMAARGRED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH89</accession>
    <name>A0A0S2DH89_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase, group 1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2461</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2461"/>
    <dbReference type="EnsemblBacteria" id="ALN57810">
        <property type="protein sequence ID" value="ALN57810"/>
        <property type="gene ID" value="GLE_2461"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2461"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2423"/>
    <dbReference type="OMA" id="SYYREGI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="34"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="200"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="388" mass="42528" checksum="69B3D4F2413926BF" modified="2016-02-17" version="1">MTRASVTSAHRGWELLPPQPRRALHLINGEHYAGAERVQDLLAQQLPRFGWDVDFACLKPGAFERERSARDSRIITVPMRSRLDMGPARRVAELLERGGYDLLHTHTVRSLLVGRFAARRARRPLLHHIHSRTDRDTENALRNRVNSAIQRFGAARAARLVAVSHGTAHYLRGLGYDDEVVRVVPNGVPVNPAPRPWIAPDGAWTLGMVALFRPRKGVEMLIDALAQLRAQGRDVSLRAVGGFESDAYREQVLAHAQARGVAEQIHWTGFTRDVSAELARIDLFVLPSLYGEGLPMVLIEALSLGLPVVATANEGVPEVLADGRAGELVPSGDATALAAAVAALMDDPARAAALAGRGLQRQRERYSDVAMARQVAAVYEEVLQEAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHA7</accession>
    <name>A0A0S2DHA7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_00445</name>
        <name evidence="1" type="ORF">GLE_2631</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000001">
        <property type="protein sequence ID" value="OPD66015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947690.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57979">
        <property type="protein sequence ID" value="ALN57979"/>
        <property type="gene ID" value="GLE_2631"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD66015">
        <property type="protein sequence ID" value="OPD66015"/>
        <property type="gene ID" value="BV903_00445"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2631"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2590"/>
    <dbReference type="OMA" id="MQAGELH"/>
    <dbReference type="OrthoDB" id="1689984at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD66015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="142" mass="15264" checksum="2C8CF038FDB21DF6" modified="2016-02-17" version="1">MSINSKARRDAKKRKLARARPVAAVGASIEPHAELRDTDGRLLGGIVRRDGEWTLGLGGRIVGGSESAARVLALLERAASLHRREGRQVSLGCSSALRRAADQELAERGLSSEQFREELEKELAIDPPPALNVVADAGDARH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHB7</accession>
    <name>A0A0S2DHB7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2456</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57805">
        <property type="protein sequence ID" value="ALN57805"/>
        <property type="gene ID" value="GLE_2456"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2456"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2418"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="76" mass="8782" checksum="E86069F77C02ADF6" modified="2016-02-17" version="1">MNRRAATASAFRRFSGRADGVRACARRRHRQPINCDLNLIFDRARDARPAHRVRRRFLLNQSIARSFSAATQGRTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHE6</accession>
    <name>A0A0S2DHE6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4142 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2478</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2478"/>
    <dbReference type="EnsemblBacteria" id="ALN57827">
        <property type="protein sequence ID" value="ALN57827"/>
        <property type="gene ID" value="GLE_2478"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2478"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2440"/>
    <dbReference type="OMA" id="RNAFMRN"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025419">
        <property type="entry name" value="DUF4142"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13628">
        <property type="entry name" value="DUF4142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4142" evidence="2">
        <location>
            <begin position="44"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="7"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="185" mass="19634" checksum="62073E914BB99A86" modified="2016-02-17" version="1">MALLLAAAAPAQDPPPTRTTSPAHAGIGGHKTAEATQRDADSLALGLLAALDENEIAAAQQAQQKRVSGPYLEFARMMQTQHGENLRRTRQLGVLSASAEVEALKSKGRAELAELGRHQGRDYESAYAKAMVAGHQDALDLVDRRLSELARSAAVKRHLAETRQHVAMHLALAKGLPAVAATAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHH8</accession>
    <name>A0A0S2DHH8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transporter, major facilitator superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_2378</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2378"/>
    <dbReference type="EnsemblBacteria" id="ALN57727">
        <property type="protein sequence ID" value="ALN57727"/>
        <property type="gene ID" value="GLE_2378"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2378"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2339"/>
    <dbReference type="OMA" id="DFFVYGI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="272"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="366"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="405"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="432"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="45"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="455" mass="48720" checksum="5A64E78C302CC738" modified="2016-02-17" version="1">MRTFFPAPRTELQQTMQTPNHANPDSMTVSVHGTDSHAEVAPGDIAVGVVIGRASEYFDFFVYGIASALVFPSVFFPHLGKLEGTLWSFAIFALAFISRPLGTVLFMWIQRRWDRSTKLTIALFLLGTCTAGIAFLPGFAKIGALSLVLLSVFRLGQGVALGGSWDGLPSLLALNAPKERRGWYAMLGQLGAPVGFMIAAALFAYLSTALSRQDFLDWGWRYPFFAAFALNVVALFARLRLVVTHEYERELGEQQLEPTPVLELFQAKGRHVVIGAFAALASYALFHIVTIFPLSWIVLYSDQSVPQFLVVQIVGAALAAGAVVASGWIADKFGRPRTLAALAAAIAMFSGFAPTLLGSGELGQDVFILVGFILLGLSYGQAAGSVTANFGAKYRYTGAALTSDLAWLIGAAFAPLVALGLCAHFGLGFVGVYLLSGAVCTMAALGVNRMLKLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHI7</accession>
    <name>A0A0S2DHI7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Biopolymer transport protein ExbB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">exbB</name>
        <name evidence="16" type="ORF">GLE_2542</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">The accessory proteins ExbB and ExbD seem to form a complex with TonB.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 13">Membrane</location>
            <topology evidence="1 13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the exbB/tolQ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2542"/>
    <dbReference type="EnsemblBacteria" id="ALN57891">
        <property type="protein sequence ID" value="ALN57891"/>
        <property type="gene ID" value="GLE_2542"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2542"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2503"/>
    <dbReference type="OMA" id="PHMVKVG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
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    </dbReference>
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    <keyword evidence="9 13" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
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            <begin position="24"/>
            <end position="45"/>
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            <end position="196"/>
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    </evidence>
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        </source>
    </evidence>
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    <evidence type="ECO:0000256" key="7">
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
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    </evidence>
    <sequence length="239" mass="24837" checksum="A3EFB08DEEFCCBBD" modified="2016-02-17" version="1">MSLPNDVSAAALTPWQMYLAADPVVKAVMIALALASVASWTVLVAKSWELSRLHRGLRRARAALLDAAQLPCDSGDQALRDGAARDLIEAARSELRLCGGGFDPAGIKERIGSRLERIELAHARQWRKGVGLLASIGAIAPFVGLFGTVWGIMNSFVGIAHANATSLAVVAPGIAEALLATALGLVAAIPAVAIYNHFTRALAGLRATLGDVSASVQQSVSRDLDRPHGRAAAAVAAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHP9</accession>
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="2 5" key="2">
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            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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    </dbReference>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
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    </evidence>
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    </evidence>
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        <source>
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        <source>
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    </evidence>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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        <text evidence="1">Belongs to the UPF0337 (CsbD) family.</text>
    </comment>
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    </dbReference>
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    </dbReference>
    <dbReference type="RefSeq" id="WP_057947664.1">
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        <property type="gene ID" value="GLE_2596"/>
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        <property type="gene ID" value="BV903_00170"/>
    </dbReference>
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    <dbReference type="PATRIC" id="fig|69.6.peg.2556"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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            <end position="56"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF05532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD65965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="65" mass="7303" checksum="FEF4740BE7990582" modified="2016-02-17" version="1">MNKDIIAGKWTQLKGQAKAKWGDLTDDDLDVAEGNAQYLAGKLQEKYGWAKDRAEKEVKDFSDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHS7</accession>
    <name>A0A0S2DHS7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_2688</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58036.1"/>
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        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2688"/>
    <dbReference type="EnsemblBacteria" id="ALN58036">
        <property type="protein sequence ID" value="ALN58036"/>
        <property type="gene ID" value="GLE_2688"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
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        <property type="entry name" value="Amoino_acid_permease_CS"/>
    </dbReference>
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        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
        <property type="entry name" value="AMINO_ACID_PERMEASE_1"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="203"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="364"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="407"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="431"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="AA_permease" evidence="7">
        <location>
            <begin position="23"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="457" mass="47528" checksum="0B905267FAFED102" modified="2016-02-17" version="1">MTASPAAASADPQLGHALKSRQLVMMGLGSAIGAGLFLGSGVGVQTAGPAVLLSYLIAGTLIIIVMRALGEMAAARPTSGAFSVYAADAMGPTAGATLGWLWWVQIVIVVAAESVGAAGLLATVWPQLPVAATSLVFMSAFTLVNLLGVRNFGEFEFWFAILKVAAILIFIAIGAALLLGLLPDVPSPGLSHFTEHGGFAPKGWAGIGAALLVVVFAFGGTEIVAVAAAETQDPERSITQAIRTVAWRILVFYIGSLAVIIAVVPWTSEALKSPFAAVLEAARIPGAATAITLVAVVALLSALNANLYGASRMIYSLAQRQEAPRFLARLSRSQVPVAAVLASVAFGFIATALELLYPDKVLPALLNVVGSTCLLVWTLSLVAQLILRRRADRAGIALPFKMWAFPYVTWLGLGILALVFVLALMTPGPRVQLLSTVGLTLGIAAVSEIARRMRARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHX0</accession>
    <name>A0A0S2DHX0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">UDP-glucose 6-dehydrogenase</fullName>
            <ecNumber evidence="4 7">1.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ugd</name>
        <name evidence="13" type="ORF">FE772_13535</name>
        <name evidence="12" type="ORF">GLE_2703</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">C3</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>H2O + 2 NAD(+) + UDP-alpha-D-glucose = 3 H(+) + 2 NADH + UDP-alpha-D-glucuronate</text>
            <dbReference type="Rhea" id="RHEA:23596"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="1.1.1.22"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; UDP-alpha-D-glucuronate biosynthesis; UDP-alpha-D-glucuronate from UDP-alpha-D-glucose: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.22" evidence="4 7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947750.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2703"/>
    <dbReference type="EnsemblBacteria" id="ALN58051">
        <property type="protein sequence ID" value="ALN58051"/>
        <property type="gene ID" value="GLE_2703"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2703"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2662"/>
    <dbReference type="OMA" id="CECLNLP"/>
    <dbReference type="OrthoDB" id="647136at2"/>
    <dbReference type="UniPathway" id="UPA00038">
        <property type="reaction ID" value="UER00491"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003979">
        <property type="term" value="F:UDP-glucose 6-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006065">
        <property type="term" value="P:UDP-glucuronate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028357">
        <property type="entry name" value="UDPglc_DH_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500134">
        <property type="entry name" value="UDPglc_DH_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="SSF52413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 10" id="KW-0520">NAD</keyword>
    <keyword evidence="5 7 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh_C" evidence="11">
        <location>
            <begin position="320"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="155"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="255"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN58051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW26531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="447" mass="48437" checksum="1FB6C9A11E6B4B1E" modified="2016-02-17" version="1">MRVTIFGTGYVGLVTGTCLADVGHDVVCVDIDQAKVEGLNRGAIPIYEPGLEPMVKANHAAGRLHFTTDAAGAIAHGDLIFIAVGTPPDEDGSADLKYVLAVAQTIGRHIERPVIVVNKSTVPVGTADKVQASIAAELAARGAQVPFDVASNPEFLKEGDAVNDCMRPDRIVIGAANPLAVEKLKRLYAPFNRNHERIVVMDVRSAELTKYAANAMLATKISFMNEIANIAEKVGADIEMVRQGIGSDPRIGWHFIYPGAGYGGSCFPKDVQALARTAQQHGYGARLLDAVESVNDSQKGHLFELIQRHYGGDVRGKTFAVWGLAFKPNTDDMREASSRRLLAQLWEAGAKVRAYDPEASEEAQRIFGEREDLVLCDSARAALADADALVVVTEWKQFRSPDFVRVRQALADAVIFDGRNLYHPDEVEAADLAYYGIGRGRSIRIDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI99</accession>
    <name>A0A0S2DI99_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58238">
        <property type="protein sequence ID" value="ALN58238"/>
        <property type="gene ID" value="GLE_2890"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2890"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2852"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="70" mass="7599" checksum="72F2CC8C368D18EB" modified="2016-02-17" version="1">MAKAARASGGARRESRRRLPSGDGAAAPSAALHRRREGWRCGSGISRALGACAAMRRRQRRRARPCPRSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIA6</accession>
    <name>A0A0S2DIA6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">6-phosphogluconolactonase</fullName>
            <shortName evidence="7">6PGL</shortName>
            <ecNumber evidence="5 7">3.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">pgl</name>
        <name evidence="9" type="ORF">GLE_2777</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12556"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="3.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.31" evidence="5 7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2777"/>
    <dbReference type="EnsemblBacteria" id="ALN58125">
        <property type="protein sequence ID" value="ALN58125"/>
        <property type="gene ID" value="GLE_2777"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2777"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2734"/>
    <dbReference type="OMA" id="CAHADAM"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00409"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01400">
        <property type="entry name" value="6PGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005900">
        <property type="entry name" value="6-phosphogluconolactonase_DevB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039104">
        <property type="entry name" value="PGLS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11054">
        <property type="entry name" value="PTHR11054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01198">
        <property type="entry name" value="pgl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine_iso" evidence="8">
        <location>
            <begin position="27"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN58125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="248" mass="27185" checksum="BAE9B107D1CED8B3" modified="2016-02-17" version="1">MLDDPAPVPHDPAQPEAAPYRWHEHRNADAWVWACAVAIAAELRRDLARRPRSRLLLSGGTTPAPVYRALARAPLDWARVDVALVDERWLQPSDPDSNAWLVKQNLLRDNAAMARFESLTRPGHGMEEAVAFANAHARQDVSAAVLGMGEDGHTASLFPGMAAFDRVLASKQPYVAIDAGGLPGAKQWSKRISLTPNGLAYARSRFLLIQGQAKREVFAQALADGNPKRWPVLLAMQGEVALDVHWCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIH8</accession>
    <name>A0A0S2DIH8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CAAX amino protease family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947852.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58189">
        <property type="protein sequence ID" value="ALN58189"/>
        <property type="gene ID" value="GLE_2841"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2841"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2799"/>
    <dbReference type="OMA" id="DEEPMFR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="246" mass="25864" checksum="87D1F9F915A93C03" modified="2016-02-17" version="1">MDAAIFSLSFAVAAFVVFALCKPFDRRLTLAAGALFALYLGLDDLVTGLASSVPALAVVGGAWNWSGKLYSLALAALVALALGIKPAALGLTLRQRHLGTSLAVLGLFVVWGLGLGLWFKPGVADAETLAFQVSMPGLAEELAYRGIAPALLLGWIGGREPRQEERMPWAAIVATAVLFGLWHGLGYARGAYSFDPISALFPFIGSLAGGWLRFRSGSLLFPLLIHSVANLAFHLSAHLDAYLGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIJ4</accession>
    <name>A0A0S2DIJ4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FMN dependent NADH:quinone oxidoreductase</fullName>
            <ecNumber evidence="6">1.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Azo-dye reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">FMN-dependent NADH-azo compound oxidoreductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">FMN-dependent NADH-azoreductase</fullName>
            <ecNumber evidence="6">1.7.1.17</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">azoR</name>
        <name evidence="9" type="ORF">FE772_14885</name>
        <name evidence="8" type="ORF">GLE_2976</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.</text>
    </comment>
    <comment type="function">
        <text evidence="6">Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 a quinone + H(+) + NADH = 2 a 1,4-benzosemiquinone + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:65952"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="ChEBI" id="CHEBI:134225"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>anthranilate + N,N-dimethyl-1,4-phenylenediamine + 2 NAD(+) = 2-(4-dimethylaminophenyl)diazenylbenzoate + 2 H(+) + 2 NADH</text>
            <dbReference type="Rhea" id="RHEA:55872"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15783"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:71579"/>
            <dbReference type="EC" id="1.7.1.17"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="5">
            <dbReference type="Rhea" id="RHEA:55874"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="6">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the azoreductase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.6.5.-" evidence="6"/>
    <dbReference type="EC" id="1.7.1.17" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947951.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2976"/>
    <dbReference type="EnsemblBacteria" id="ALN58324">
        <property type="protein sequence ID" value="ALN58324"/>
        <property type="gene ID" value="GLE_2976"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2976"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2937"/>
    <dbReference type="OMA" id="GAPFYNF"/>
    <dbReference type="OrthoDB" id="1402654at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016652">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01216">
        <property type="entry name" value="Azoreductase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003680">
        <property type="entry name" value="Flavodoxin_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023048">
        <property type="entry name" value="NADH:quinone_OxRdtase_FMN_depd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02525">
        <property type="entry name" value="Flavodoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2 6" id="KW-0288">FMN</keyword>
    <keyword evidence="4 6" id="KW-0520">NAD</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin_2" evidence="7">
        <location>
            <begin position="1"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="85"/>
            <end position="88"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW26739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="192" mass="20640" checksum="BA0F7AADBF8F3606" modified="2016-02-17" version="1">MKLLHIDSSALGANSVTRELSAAVAARWQDDLPGVVVDHLDLDADPIPHLTGRSLAKDDPAENDRSERILQQFLQADVIVIGAPMYNFGIPSTLKAWIDRIAVAGKTFRYTAEGPEGLAKGKKAIIVSGRGGLHSGQPSDFQETYLRHVLGFVGVTDVEFVRAEGVSYSPQHRADALAAAHASIPRPQRLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIP4</accession>
    <name>A0A0S2DIP4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2852</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="276" mass="29116" checksum="A905C2CC4425C3A1" modified="2016-02-17" version="1">MCLIALAWQHHPRYRLALIANRDEAHARPTAPAGADPDDAHAFGGRDLSQGGSWLMVSDRGRLAAVTNVRDGRQPETAPRSRGALVRDFVHGAMSARQCLDALRADAAQFGRFNLLLWDGDALRFGSNHPPAGAGGYQTFAVAPGVHAMTNGAFDAAWPKSGLATRALSAWLDSPASLQAPLRRDGDAPSSADPGLAMLLAAMADTTLAPDEALPDTGVGLELEHLLSPPFVLGERYGTRCSTIVLVGADGIDFIERRYGPNGADGGESATHLPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIW5</accession>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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            <end position="26"/>
        </location>
    </feature>
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            <begin position="27"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58587.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW26927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="69" mass="7087" checksum="0B3FF0C4973BE9CF" modified="2016-02-17" version="1">MKRMHMGWLAAAALVFGLGFGASASASDPGCYSTCQELANDCRAQAGGGSTAHCGRLYRECIAACNLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ62</accession>
    <name>A0A0S2DJ62_LYSEN</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58449">
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        <property type="gene ID" value="GLE_3102"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="79" mass="8177" checksum="B84FFA7F1D33C7E9" modified="2016-02-17" version="1">MWEGLQARRFCSESPRPERKASGLKALPQKSRIAAATQRSPQATESASRAGAALLSSIRGATDAPQAARSGSPAVSGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJC5</accession>
    <name>A0A0S2DJC5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">30S ribosomal protein S20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">rpsT</name>
        <name evidence="11" type="ORF">BV903_20975</name>
        <name evidence="13" type="ORF">D9T17_11765</name>
        <name evidence="12" type="ORF">FE772_16285</name>
        <name evidence="10" type="ORF">GLE_3290</name>
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    <organism evidence="10 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="10 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 14">C3</strain>
        </source>
    </reference>
    <reference evidence="11 15" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 15">B25</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">OH11</strain>
        </source>
    </reference>
    <reference evidence="12 17" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Binds directly to 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the bacterial ribosomal protein bS20 family.</text>
    </comment>
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        <property type="protein sequence ID" value="ALN58636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000066">
        <property type="protein sequence ID" value="OPD61955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="protein sequence ID" value="ROU06833.1"/>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_RCTY01000028.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3290"/>
    <dbReference type="EnsemblBacteria" id="ALN58636">
        <property type="protein sequence ID" value="ALN58636"/>
        <property type="gene ID" value="GLE_3290"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD61955"/>
        <property type="gene ID" value="BV903_20975"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3290"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3241"/>
    <dbReference type="OMA" id="GVIHKNA"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:translation"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Ribosomal_S20_sf"/>
    </dbReference>
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        <property type="entry name" value="PTHR33398"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0699">rRNA-binding</keyword>
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        </location>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN58636.1"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="OPD61955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW26961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROU06833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="90" mass="9721" checksum="F68AE8D2DFCC8BC9" modified="2016-02-17" version="1">MANIKSAKKRAKQTVVRNARNASQRSMLRTAVKKVLKALGENDAAGAKSAFDVAQPILDRFSARGLIHKNKAARHKSRLSARIKALATAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJH5</accession>
    <name>A0A0S2DJH5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Exodeoxyribonuclease 7 small subunit</fullName>
            <ecNumber evidence="3">3.1.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Exodeoxyribonuclease VII small subunit</fullName>
            <shortName evidence="3">Exonuclease VII small subunit</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">xseB</name>
        <name evidence="7" type="ORF">BV903_17820</name>
        <name evidence="9" type="ORF">D9T17_11270</name>
        <name evidence="8" type="ORF">FE772_16745</name>
        <name evidence="6" type="ORF">GLE_3396</name>
    </gene>
    <organism evidence="6 10">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 10">C3</strain>
        </source>
    </reference>
    <reference evidence="7 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">OH11</strain>
        </source>
    </reference>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 13">YC36</strain>
        </source>
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        <reaction evidence="3">
            <text>Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
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        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterooligomer composed of large and small subunits.</text>
    </comment>
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        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Exonuc_7_S"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Exonuc_VII_S"/>
    </dbReference>
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        <property type="entry name" value="Exonuc_VII_ssu_sf"/>
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        <property type="entry name" value="PTHR34137"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="xseB"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_00337"/>
        </source>
    </evidence>
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    <evidence type="ECO:0000256" key="5">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW27045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROU07076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="91" mass="9920" checksum="3A7B036E8AF1BC6C" modified="2016-02-17" version="1">MPRKTTTEASPVADFEQSLDALEQLVEKMEHGEMSLEESLAAYERGVGLYRRCQSALEQAELRVRLLTDPQEPASAEPFGNAGPPGSDVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJK5</accession>
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        <submittedName>
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        </submittedName>
    </protein>
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    </gene>
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        </lineage>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ALN58821.1"/>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN58821">
        <property type="protein sequence ID" value="ALN58821"/>
        <property type="gene ID" value="GLE_3476"/>
    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW27101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="396" mass="42970" checksum="0E23717848E184CA" modified="2016-02-17" version="1">MTPSRPSLLRLREGHAKVGFAELFFDLVFVFAVTQLSHTLLEHLDLAGALRTGLLFLGVWWLWIYTSWVTNWLDPEKVPVRLMIFALMLGGLLLSSSLPHAFAERGLAYGATFAAMQVGRTAFMLWALRGGRSPGNFRNFVRILVWLCVSAVFWLLGGLAEPEARLWWWLAAVAIEYLGPISFFRVPGLGRSSLTDWDIEGGHLSERCGLFVIIALGESILITGATYAKLDWNPTTLAAFVSAFLGSVAMWWIYFDSGAARGEHRMVHGGDAARQARLAYTYLHLPIVGGIIVCAVADELVLVHPGHADAAGVAAIVGGPALYLLGCALFKWVTNTRKFPPLSHLAGLAMLLALWFAAGPLHLSALALGAATTTVFVVVAGWETAALRRGNAAPAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJL0</accession>
    <name>A0A0S2DJL0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">BCCT family transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Transporter, betaine/carnitine/choline transporter (BCCT) family</fullName>
        </submittedName>
    </protein>
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        <name evidence="9" type="ORF">FE772_17130</name>
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    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="QCW27102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948321.1">
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_3478"/>
    <dbReference type="EnsemblBacteria" id="ALN58823">
        <property type="protein sequence ID" value="ALN58823"/>
        <property type="gene ID" value="GLE_3478"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3478"/>
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        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071705">
        <property type="term" value="P:nitrogen compound transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000060">
        <property type="entry name" value="BCCT_transptr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30047">
        <property type="entry name" value="PTHR30047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02028">
        <property type="entry name" value="BCCT"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="bcct"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="306"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="336"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="391"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="430"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="459"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="507"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW27102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="534" mass="58131" checksum="CF1924F7D0A76C7F" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJT4</accession>
    <name>A0A0S2DJT4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3442</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58787">
        <property type="protein sequence ID" value="ALN58787"/>
        <property type="gene ID" value="GLE_3442"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3442"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="69" mass="7418" checksum="E4F39E99E5E6468E" modified="2016-02-17" version="1">MRSDHGRVGSVLGGRGVWRAQARGREAPSVPRRANGKRRTFECAAPRRDSPRAAAGPGQHASRAGRRST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJZ4</accession>
    <name>A0A0S2DJZ4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">S-adenosylmethionine:tRNA ribosyltransferase-isomerase</fullName>
            <ecNumber evidence="5">2.4.99.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Queuosine biosynthesis protein QueA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">queA</name>
        <name evidence="7" type="ORF">FE772_17310</name>
        <name evidence="6" type="ORF">GLE_3516</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>7-aminomethyl-7-carbaguanosine(34) in tRNA + S-adenosyl-L-methionine = adenine + epoxyqueuosine(34) in tRNA + H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:32155"/>
            <dbReference type="Rhea" id="RHEA-COMP:10342"/>
            <dbReference type="Rhea" id="RHEA-COMP:10346"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:82833"/>
            <dbReference type="ChEBI" id="CHEBI:82834"/>
            <dbReference type="EC" id="2.4.99.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the QueA family.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.17" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948349.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3516"/>
    <dbReference type="EnsemblBacteria" id="ALN58860">
        <property type="protein sequence ID" value="ALN58860"/>
        <property type="gene ID" value="GLE_3516"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3516"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3460"/>
    <dbReference type="OMA" id="YSYGDGM"/>
    <dbReference type="OrthoDB" id="368001at2"/>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051075">
        <property type="term" value="F:S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00113">
        <property type="entry name" value="QueA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003699">
        <property type="entry name" value="QueA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042118">
        <property type="entry name" value="QueA_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042119">
        <property type="entry name" value="QueA_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036100">
        <property type="entry name" value="QueA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30307">
        <property type="entry name" value="PTHR30307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02547">
        <property type="entry name" value="Queuosine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111337">
        <property type="entry name" value="SSF111337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00113">
        <property type="entry name" value="queA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 5" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW27133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="346" mass="38081" checksum="B483B13E5A4FDE5B" modified="2016-02-17" version="1">MKKSDFHYDLPPELIAQAPLPERSASRLLRVPPAPAALEDRNVRDLPQLLQPGDLLVFNDTRVIPARLFGQKSTGGRVEILIERLLGGNEARAQLGVSKSPKEGARIAMDAGGEAEVLGRDGEFYRLRFHVSESLEQWLLHAGRLPLPPYIQREPGRDDAERYQTVFAREVGAVAAPTAGLHFDESLLQALRERGVQFGHVTLHVGAGTFQPVRADDLSQHVMHSEWLNVGAGLVEQIRRTRAAGGRVIGVGTTVVRALESATRQGGGELQPYAGETRLFILPGYRIRSVDAMVTNFHLPESTLLMMISAFAGKQRVFDAYAHAIAQRYRFFSYGDAMLLSASDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK30</accession>
    <name>A0A0S2DK30_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aga operon transcriptional repressor</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">DeoR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BV903_07345</name>
        <name evidence="8" type="ORF">D9T17_09875</name>
        <name evidence="7" type="ORF">FE772_17990</name>
        <name evidence="5" type="ORF">GLE_3659</name>
    </gene>
    <organism evidence="5 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 9">C3</strain>
        </source>
    </reference>
    <reference evidence="6 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">OH11</strain>
        </source>
    </reference>
    <reference evidence="7 12" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 12">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000014">
        <property type="protein sequence ID" value="OPD64576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000023">
        <property type="protein sequence ID" value="ROU07265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948449.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3659"/>
    <dbReference type="EnsemblBacteria" id="ALN59003">
        <property type="protein sequence ID" value="ALN59003"/>
        <property type="gene ID" value="GLE_3659"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64576">
        <property type="protein sequence ID" value="OPD64576"/>
        <property type="gene ID" value="BV903_07345"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3659"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3603"/>
    <dbReference type="OMA" id="FDNDVTR"/>
    <dbReference type="OrthoDB" id="1629121at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014036">
        <property type="entry name" value="DeoR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018356">
        <property type="entry name" value="Tscrpt_reg_HTH_DeoR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00455">
        <property type="entry name" value="DeoRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08220">
        <property type="entry name" value="HTH_DeoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00037">
        <property type="entry name" value="HTHLACR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00420">
        <property type="entry name" value="HTH_DEOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00894">
        <property type="entry name" value="HTH_DEOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="4">
        <location>
            <begin position="6"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD64576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW27240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROU07265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="260" mass="28589" checksum="A71F7E1C42CB93E5" modified="2016-02-17" version="1">MATRNTRSRRQQILQCLIEQGSVQVAELVERFEVSAVTIRADLSHIESQGLATRTHGGATLVRTPPQEQDIHEKDALNLPLKERIGARAAQLVQAGDNIIIDSGSTTMTLARHLRGHRDVTVMTNGLNIAWELANAPGVDVLLSGGLLRKQSLSLQGSQAEASLNAYSFDTLFLGVDGLDLQFGLTTHDEAEARLNHRMVEHARRIVVLTDASKFGRVSLHRIARLDQIHAIITDPGIDERYREGLLRLGIEVIIAEPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKB0</accession>
    <name>A0A0S2DKB0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glucose/sorbosone dehydrogenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">L-sorbosone dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_17005</name>
        <name evidence="3" type="ORF">GLE_3452</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948304.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58797">
        <property type="protein sequence ID" value="ALN58797"/>
        <property type="gene ID" value="GLE_3452"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3452"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3400"/>
    <dbReference type="OrthoDB" id="1150223at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012938">
        <property type="entry name" value="Glc/Sorbosone_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07995">
        <property type="entry name" value="GSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726673" evidence="1">
        <location>
            <begin position="24"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="GSDH" evidence="2">
        <location>
            <begin position="66"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="392" mass="43173" checksum="2B27679111378FAB" modified="2016-02-17" version="1">MNRRSAFSFCLAAALALPFAAAAAALTPHPVALDDGRSFSLDLPADLEIVPVVQGLKRVRFFARSPDGRLFVTDLHDLSDNKLGRVYALDGWDEKRERYTKVSVYLDKQRNPNSVAFHTDARGQQWLYVANTDKLLRYRYRNGDVKPSSEPETLATFPDYGLSYKYGGWHLTRSLAFGGGKLYVAVGSSCNACVEKEEVRAAILQMNPDGSGQRTYARGLRNAVGLLYRDGQLYATNQGSDHLGDDKPDETMFAVKDGADYGWPYCYFSRGKVLADPKFPRKQGCAAVPKTFAYFPSHASALGLTWFPASDGGQLRDEFAVALHGSSKLKLGHGYRIVRVGADGRARGDLVAGFLQDGKSVGRPCDVLALGRDSFLFTDDKSGVIYKVRPKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKS1</accession>
    <name>A0A0S2DKS1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC-2 type transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_19060</name>
        <name evidence="2" type="ORF">GLE_3878</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948617.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3878"/>
    <dbReference type="EnsemblBacteria" id="ALN59221">
        <property type="protein sequence ID" value="ALN59221"/>
        <property type="gene ID" value="GLE_3878"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3878"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3817"/>
    <dbReference type="OMA" id="FHISYIE"/>
    <dbReference type="OrthoDB" id="1543624at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="261" mass="28558" checksum="62FD5710F0658551" modified="2016-02-17" version="1">MLLNHLIQSLRQPDHWLYGSWLDTAIRYRRMRLGLLWLLVPTAVYIWGIGGFLASMQPGLDASRFLAHVALGFAVFRMVSAVMTDSTSVFSGFQYFIYDGHLRLTDYILRNLARSFYYFLLSLPLVLAAAIASPDFTPGGLPLATLGLAVVLVNLFSFSVLLGLAGARYPDLGELMGSVMMAAFLVTPVVWYPGAVPADSTPGLLMRANPFHHLLVAVRAPLLGETIDPASWLYLPILTVAGLVAAALAYRGCARRVAAWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKW2</accession>
    <name>A0A0S2DKW2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidase, M28 family/proprotein convertase P-domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_3837</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948590.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3837"/>
    <dbReference type="EnsemblBacteria" id="ALN59180">
        <property type="protein sequence ID" value="ALN59180"/>
        <property type="gene ID" value="GLE_3837"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3837"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3779"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002884">
        <property type="entry name" value="P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="PTHR12147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01483">
        <property type="entry name" value="P_proprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51829">
        <property type="entry name" value="P_HOMO_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595771" evidence="3">
        <location>
            <begin position="36"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="domain" description="P/Homo B" evidence="4">
        <location>
            <begin position="438"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="558" mass="59082" checksum="DFF39E1DB6328DBF" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKW6</accession>
    <name>A0A0S2DKW6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Energy transducer TonB</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="11">TonB family C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FE772_19450</name>
        <name evidence="11" type="ORF">GLE_3965</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TonB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948680.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3965"/>
    <dbReference type="EnsemblBacteria" id="ALN59307">
        <property type="protein sequence ID" value="ALN59307"/>
        <property type="gene ID" value="GLE_3965"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3965"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3902"/>
    <dbReference type="OMA" id="NRDGSLY"/>
    <dbReference type="OrthoDB" id="1664469at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="TonB_C" evidence="10">
        <location>
            <begin position="207"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="73"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="110"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN59307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW27490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="293" mass="32071" checksum="A9C01F3267D03DCD" modified="2016-02-17" version="1">MSAGVPHLPGGGLAEPQRFSATMVLSVLVHGIFLLGVGYTLERAAPVVPTLDVILTQTQTALTPKQADFLAQANNQGGGEHDKSTRPRDNQSGPSPQAEAGVAQMALRAQSPAAQPQPTARVVSSTRGETTTARERIAQTPAERPLPNGQRKIEHDIEMARLAAEIHMRSERYAKRPTRKFVSASTTEYAWAGYLREWVDRVERVGNLNYPDEARRRRLAGQVVISVAVRRNGSVERADIVRSSGVRLLDDSALRIARLAEPYPPLPKTEENPDILHVTRTWNFLPGGSLVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL56</accession>
    <name>A0A0S2DL56_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">ABC transporter, ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BV903_16125</name>
        <name evidence="8" type="ORF">FE772_19055</name>
        <name evidence="6" type="ORF">GLE_3877</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">C3</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000042">
        <property type="protein sequence ID" value="OPD62918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948616.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3877"/>
    <dbReference type="EnsemblBacteria" id="ALN59220">
        <property type="protein sequence ID" value="ALN59220"/>
        <property type="gene ID" value="GLE_3877"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62918">
        <property type="protein sequence ID" value="OPD62918"/>
        <property type="gene ID" value="BV903_16125"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3877"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3816"/>
    <dbReference type="OrthoDB" id="887953at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03220">
        <property type="entry name" value="ABC_KpsT_Wzt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015860">
        <property type="entry name" value="ABC_transpr_TagH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="31"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="63"/>
            <end position="70"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD62918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW27423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="381" mass="42018" checksum="68CEE533AC97BFCA" modified="2016-02-17" version="1">MAMDVHLRAEQVALELPLDMQNTPVGRKLGLRSSLSGSTRRYVSVLSGIDFAAADGDRIAVIGLNGAGKTTLLRVLNGAFQPTRGWVRRHGRTQSLLTPMLGFAEQASVAENVYLRGTAMGLRRAQLQSALGDILEFANLGDRASHRLHTLSAGQRTRLGFAISTAVQPDILLMDEWIATGDSAFLHRAQERMTDRFHGSRIVVMAGHSTELHRRLCNKALVLDAGRMRFFGAIEDGLACYRDLVSAADGRLRQQLAAQDPLLFGNASGFVEKVRIREGRIEIEGWAIGERGREIEVLCVEVDGQRRFIEGFDRVEREDVLRALAKRSGRYGFRFAFADPAGRERESLQTMLVSAGMERERLGAPLQRLANALEDEAPALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLJ4</accession>
    <name>A0A0S2DLJ4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4168</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59510">
        <property type="protein sequence ID" value="ALN59510"/>
        <property type="gene ID" value="GLE_4168"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4168"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4110"/>
    <dbReference type="OMA" id="WRERLEV"/>
    <dbReference type="OrthoDB" id="1706771at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="296" mass="32712" checksum="E375B97C84E198EF" modified="2016-02-17" version="1">MPMSLLSKLFRGRRPARADAGVCPAPLDLHAFTERYAQALRALWPQARLRVGHGARLADTRIDWSLPDGFAATQFVASGYRRYLDAPEALERVLAEQVEAARALQRRHALGAQAGDDDAILPVLKTRGWHEVALQQARAIGGGAGIAFVVEALAGDLVLSFVEDRADSMDYLSPSEAERRGLAPDALRARALRNLQRFLPELEIEGGDGRYVLRLDRNYDASMALLFEHWRERAPVRGEPVFAIAARDELWLCGRDDDEGVQRLGEAAAEISRTSAYGLSSALFVWRDGALRVLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLK6</accession>
    <name>A0A0S2DLK6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ISMsm8, transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_4034</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the transposition of the insertion element.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transposase IS30 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59376">
        <property type="protein sequence ID" value="ALN59376"/>
        <property type="gene ID" value="GLE_4034"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4034"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3976"/>
    <dbReference type="OMA" id="MHTIARS"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025246">
        <property type="entry name" value="IS30-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001598">
        <property type="entry name" value="Transposase_IS30_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13936">
        <property type="entry name" value="HTH_38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01043">
        <property type="entry name" value="TRANSPOSASE_IS30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="4">
        <location>
            <begin position="164"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="133"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="333" mass="38352" checksum="7B4086B365C83181" modified="2016-02-17" version="1">MAWVRQGLSARQIARELQRAQSIITRELRRNGRALIGRPRKVPGYDAALAQQRAVGLRQRPRRPRKLRGDAALWPEVLILLRAGWSPQQASLKLRRLHPDDSAWHVSHETIYRALYAMPRGELRRQILLRHKRAARRPQRRTPDGRGRMTDLPSIHDRPPEVEERLLPGHWEGDLIKGARNQSSVGVLVCRQSLFVMLVRLPDATAQSVLEGFTQAFARLPPRLRKTLTYDQGKEMALHRQLSKGVGLNVYFADPHSPWQRGRCENINGLLRQYLPKGTDLSVHSQRDLDRIAWRLNMRPRVSLDVRMPAEVFLERLYGRPVNFSIEDVIAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLL1</accession>
    <name>A0A0S2DLL1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aspartate--tRNA(Asp/Asn) ligase</fullName>
            <ecNumber evidence="7">6.1.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Aspartyl-tRNA synthetase</fullName>
            <shortName evidence="7">AspRS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Non-discriminating aspartyl-tRNA synthetase</fullName>
            <shortName evidence="7">ND-AspRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">aspS</name>
        <name evidence="10" type="ORF">FE772_19975</name>
        <name evidence="9" type="ORF">GLE_4069</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + L-aspartate + tRNA(Asx) = AMP + diphosphate + L-aspartyl-tRNA(Asx)</text>
            <dbReference type="Rhea" id="RHEA:18349"/>
            <dbReference type="Rhea" id="RHEA-COMP:9710"/>
            <dbReference type="Rhea" id="RHEA-COMP:9711"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.23"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.23" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948760.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4069"/>
    <dbReference type="EnsemblBacteria" id="ALN59411">
        <property type="protein sequence ID" value="ALN59411"/>
        <property type="gene ID" value="GLE_4069"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4069"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4012"/>
    <dbReference type="OMA" id="YQLDVEM"/>
    <dbReference type="OrthoDB" id="226836at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050560">
        <property type="term" value="F:aspartate-tRNA(Asn) ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00044">
        <property type="entry name" value="Asp_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004524">
        <property type="entry name" value="Asp-tRNA-ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004115">
        <property type="entry name" value="GAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029351">
        <property type="entry name" value="GAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF5">
        <property type="entry name" value="PTHR22594:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02938">
        <property type="entry name" value="GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55261">
        <property type="entry name" value="SSF55261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00459">
        <property type="entry name" value="aspS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="141"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Aspartate" evidence="7">
        <location>
            <begin position="193"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="215"/>
            <end position="217"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="447"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="481"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="488"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="533"/>
            <end position="536"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for tRNA non-discrimination" evidence="7">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN59411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="588" mass="65236" checksum="D9E278E8E3653386" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLR5</accession>
    <name>A0A0S2DLR5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Type II secretion system protein K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">gspK</name>
        <name evidence="13" type="ORF">GLE_4176</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the GSP K family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4176"/>
    <dbReference type="EnsemblBacteria" id="ALN59518">
        <property type="protein sequence ID" value="ALN59518"/>
        <property type="gene ID" value="GLE_4176"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4176"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4118"/>
    <dbReference type="OMA" id="RKRWIAD"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005628">
        <property type="entry name" value="GspK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038072">
        <property type="entry name" value="GspK_central_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38831">
        <property type="entry name" value="PTHR38831"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03934">
        <property type="entry name" value="T2SSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002786">
        <property type="entry name" value="XcpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158544">
        <property type="entry name" value="SSF158544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR002786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN59518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="327" mass="35010" checksum="1F6CD01F2D84279A" modified="2016-02-17" version="1">METGMGDRETTKRLRGVGMVARPRVDRDVAFAGPSRTRGAALLLVMWLVALLTALIGAFALTARTENLQGRVQVRGLVAHNAARAGVEYALTRVAMSDQKLQWLPDGRPNRWRYGDAQLEIKIVDENGKVDLNQADAQLLTALLQATGKMEQSEAARLAGAIIDWRDADTLTQPAGGAEDADYASAGRPYGAKDAEFESVAELQQVLGISPELYARIEPLVTVYSGRTRPEQAFAAKEVLDAMGLNGADLVRQRERNQPGSQLQGAGAGGVGGGLVGERSGTYSIESRARLTDGRESVLRVVVRAGGGAVPGMPYTPLRWEEGASTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLU0</accession>
    <name>A0A0S2DLU0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thiamine-monophosphate kinase</fullName>
            <shortName evidence="2">TMP kinase</shortName>
            <shortName evidence="2">Thiamine-phosphate kinase</shortName>
            <ecNumber evidence="2">2.7.4.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 5" type="primary">thiL</name>
        <name evidence="5" type="ORF">GLE_4149</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + thiamine phosphate = ADP + thiamine diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15913"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine diphosphate from thiamine phosphate: step 1/1.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thiamine-monophosphate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.16" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948825.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4149"/>
    <dbReference type="EnsemblBacteria" id="ALN59491">
        <property type="protein sequence ID" value="ALN59491"/>
        <property type="gene ID" value="GLE_4149"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4149"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4091"/>
    <dbReference type="OMA" id="HFRRDWS"/>
    <dbReference type="OrthoDB" id="1016556at2"/>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00142"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009030">
        <property type="term" value="F:thiamine-phosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02194">
        <property type="entry name" value="ThiL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02128">
        <property type="entry name" value="TMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006283">
        <property type="entry name" value="ThiL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30270">
        <property type="entry name" value="PTHR30270"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005303">
        <property type="entry name" value="Thiam_monoph_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01379">
        <property type="entry name" value="thiL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AIRS" evidence="3">
        <location>
            <begin position="30"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="4">
        <location>
            <begin position="156"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="31"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="126"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>5</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="346" mass="35383" checksum="7F53BC735403F61D" modified="2016-02-17" version="1">MAEFDLIAAIRARAAALADARGDVALGIGDDAALLAPPAGRQLVVATDTLNRGVHFADDAAAGDIGWKSLAVNLSDLAAMGAEPAWCTLSLSLPDGDARARAAFVEGFADGFLELAARHRVALVGGDTTRGPLSVCVTAIGFVEPGWALRRDAAGVGDEIWVTGTLGDAGTALALDGIEGYRDFAVRRIDGADAGAGVDSEADAASAWLYQRLRRPQPRVAAGRALRGLARAGIDVSDGLLADLGHICVASGVGACLDAAALPASPALLAACAADARRALQLGGGDDYELCFTAPARQRDSIARALAAADTPAVVIGRIEAEPGVRVRLADGVMWTPSKRGYQHFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM12</accession>
    <name>A0A0S2DM12_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_19610</name>
        <name evidence="1" type="ORF">GLE_4001</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59343">
        <property type="protein sequence ID" value="ALN59343"/>
        <property type="gene ID" value="GLE_4001"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4001"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3937"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="166" mass="19043" checksum="4D03FB31F919B573" modified="2016-02-17" version="1">MSDTKPDTTPLRATDTSRRRYLCLAAAALLLVFGRPAGHYAGFCFARWEFIKEDERNRAVYNFLRERNIQRLTGVDGAVIRIEDNGFHYSDYASFKRANPDCCSYSERGPENIAMKTHAQLSGGQRYFVRVQYSPVHPDQTRILGEEPYVYHLSISNCAEVGWIRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM28</accession>
    <name>A0A0S2DM28_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sel1 repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_20515</name>
        <name evidence="2" type="ORF">GLE_4182</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948851.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
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        <property type="gene ID" value="GLE_4182"/>
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    <dbReference type="KEGG" id="lez:GLE_4182"/>
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    <dbReference type="OMA" id="PYACKYL"/>
    <dbReference type="OrthoDB" id="1018734at2"/>
    <dbReference type="Proteomes" id="UP000061569">
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        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="417" mass="44750" checksum="7B72EBD4BD3545C2" modified="2016-02-17" version="1">MKRLLHGLVLLCGLAAADAVAGCAAAEETVAACRIEGQQKQVSICLYEDESGPMDVAYRYGPVQGKEELVLRVPLMELGYLTANGAGVTVDETATFASGDHSYRVTFGFRDGRKPDPSALHKFGTVQVLRQGATLAELACAPETIVRTPDLLLERMRERGRTHASDGTTLSNYDIDRPGPLSEAAPCARKNDVDTCWSLGVSAARAGDLALALGYYDKSCDAGFVTYGCYDGGKLYLHNRQLRDYAKAYERLDRSCKGSDPGQAPYACKYLGWMHQTGIGAKKDNAEAWRLLSAACFVRAEEPLIDGEGCDLLAKTILIGHPLGDAQAQRNSVGSGYLVYLALAMGCTDAADTVCAKAKTMLADAKAARAAWVAYCDEDSGDCAGMLQPQENFGATLSQRERLFAHYQDALKTLGAP</sequence>
</entry>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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            <begin position="26"/>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
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</entry>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
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    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="ALN59798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="251" mass="27845" checksum="5BF73436A4E823FC" modified="2016-02-17" version="1">MAAMSFPVRAITLDLDDTIWPIAPVMLRAEAVLDQWLRTHAPRTAALYPIDAVRALRDRIAGERPDLAHDYTTQRRLTLQHMLRESGDDLALAEPAFDAFFAARCEVEHYADSEAALARLAARVPLAALSNGNADLKRIGLMPLFRFQLGAREHGRAKPDASIFHAACARLEFEPAQVLHVGDDIEMDVVGGRGAGLRTCWINREARQWPGQHPRPDLEFSTLTELADWLDRTSLDRAVVDGASRTDTTCA</sequence>
</entry>
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        </submittedName>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="gene ID" value="GLE_4394"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4394"/>
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    <dbReference type="OMA" id="YRFAHRE"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="164" mass="17070" checksum="5DC4518BD5ACE7EC" modified="2016-02-17" version="1">MAGRAHPMQAKYLLARTALRDATWFFDTFGGADGSGCLARFWELVGSELPEHERVAAQGLAAQGLALDDGSPALLLSLPAPERNDAHFVAAVAGSGGVRVFCLERSLSFPEQRECTVIAELAADHRANWGNGPAADAGAFLAAVDAIVSGARPGPMATVPMQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMF0</accession>
    <name>A0A0S2DMF0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_4311</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4311"/>
    <dbReference type="EnsemblBacteria" id="ALN59652">
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        <property type="gene ID" value="GLE_4311"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4311"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
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        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001322">
        <property type="entry name" value="Lamin_tail_dom"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594971" evidence="2">
        <location>
            <begin position="24"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="domain" description="LTD" evidence="3">
        <location>
            <begin position="11"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1150"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1150"/>
            <end position="1167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1175" mass="121941" checksum="314640397806FB56" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMJ2</accession>
    <name>A0A0S2DMJ2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4408</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59749">
        <property type="protein sequence ID" value="ALN59749"/>
        <property type="gene ID" value="GLE_4408"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4408"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4347"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="179" mass="20604" checksum="6624AAF49A1B9D87" modified="2016-02-17" version="1">MAQTKPVASEEAPARVAVSRPAKPACPSQDFKQFLKSFANRGDVQAAYTAQPYKVKLPYYWVHSTAAGDPRYPRWDVQERHGAAQIGYRFDTRTNAYVSDSGKLALDEQWRRPEQAALKPRKIGGFKIKRLSAGRYEVVADGFVHSYVKKSGCWYFEQSWSFEPLAYCKWPEQCKRWQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMX1</accession>
    <name>A0A0S2DMX1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_21890</name>
        <name evidence="1" type="ORF">GLE_4484</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949090.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59825">
        <property type="protein sequence ID" value="ALN59825"/>
        <property type="gene ID" value="GLE_4484"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4484"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4421"/>
    <dbReference type="OrthoDB" id="1752780at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="146" mass="16533" checksum="EBA63C5580326C8C" modified="2016-02-17" version="1">MDAAFLAATGTLRYSPQLGHGGHTRRDGGSTLWWLIVDCDPELGRYLRHQFLLGHRRTRQLQSPLWGAHISAIRGERPPLEALWKRWDGATVAFEYDPAVRETDGFVWCPVRCERLLTLREELGLPREPQPALHLTIGNSRVGGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN12</accession>
    <name>A0A0S2DN12_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RtcB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_22795</name>
        <name evidence="4" type="ORF">GLE_4681</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="3">Binds 2 manganese ions per subunit.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949233.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4681"/>
    <dbReference type="EnsemblBacteria" id="ALN60022">
        <property type="protein sequence ID" value="ALN60022"/>
        <property type="gene ID" value="GLE_4681"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4681"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4617"/>
    <dbReference type="OMA" id="PGSMGDY"/>
    <dbReference type="OrthoDB" id="1384936at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008452">
        <property type="term" value="F:RNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001233">
        <property type="entry name" value="RtcB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036025">
        <property type="entry name" value="RtcB-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01139">
        <property type="entry name" value="RtcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103365">
        <property type="entry name" value="SSF103365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="GMP-histidine intermediate" evidence="1">
        <location>
            <position position="335"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="168"/>
            <end position="172"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="279"/>
            <end position="280"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="311"/>
            <end position="314"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="335"/>
            <end position="338"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="405"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW28047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="406" mass="44238" checksum="75E5BDBF8F59A3D5" modified="2016-02-17" version="1">MSTPHYELLHADEGVAPVKAWIRGVPVDEGAKRQLRNIAALPHVGPWVAAMPDVHLGKGATVGSVVPTRGAIIPAAVGVDIGCGMAAVRTTLRTQDLPDSLARVRAAIEHCVPVGNGRGGEHRRLPDSHATRLAKSGLATRLDAIHAKHRKLRTDKLDKQIGTLGGGNHFIELCLDEAGAVWVMLHSGSRGTGNLIGSYFIELARIKLEKRTLGFHLPDKDLAFLLEGEPLFDDYVEAVGWAQDYARHNREAMMDRVLHAMRIQLPKFQLDKTAVNCHHNYVQREQHFGEPLWVTRKGAVSAREGELGIIPGSMGARSYIVRGKGNADSFHSCSHGAGRVMSRAEARRSITLKQHREATAHVECRKDAAVIDESPAAYKPIEAVMAAQADLVEVVHTLRQVVCIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN23</accession>
    <name>A0A0S2DN23_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Octanoyltransferase</fullName>
            <ecNumber evidence="6 7">2.3.1.181</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lipoate-protein ligase B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoyl/octanoyl transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 12" type="primary">lipB</name>
        <name evidence="13" type="ORF">FE772_21850</name>
        <name evidence="12" type="ORF">GLE_4476</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">C3</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6 7">Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6 7">
            <text>L-lysyl-[protein] + octanoyl-[ACP] = H(+) + holo-[ACP] + N(6)-octanoyl-L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9636"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78463"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="EC" id="2.3.1.181"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 6 7">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="6">In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the LipB family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.181" evidence="6 7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949084.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4476"/>
    <dbReference type="EnsemblBacteria" id="ALN59817">
        <property type="protein sequence ID" value="ALN59817"/>
        <property type="gene ID" value="GLE_4476"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4476"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4413"/>
    <dbReference type="OMA" id="GEVTYHC"/>
    <dbReference type="OrthoDB" id="1806796at2"/>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00592"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033819">
        <property type="term" value="F:lipoyl(octanoyl) transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16444">
        <property type="entry name" value="LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00013">
        <property type="entry name" value="LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000544">
        <property type="entry name" value="Octanoyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020605">
        <property type="entry name" value="Octanoyltransferase_CS"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016262">
        <property type="entry name" value="LPLase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00214">
        <property type="entry name" value="lipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01313">
        <property type="entry name" value="LIPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="11">
        <location>
            <begin position="47"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6 9">
        <location>
            <begin position="86"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6 9">
        <location>
            <begin position="153"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6 9">
        <location>
            <begin position="166"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="6 8">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <feature type="site" description="Lowers pKa of active site Cys" evidence="6 10">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR016262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN59817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW27896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="231" mass="25143" checksum="FFC05911A1774B0B" modified="2016-02-17" version="1">MDAVVDAVAEFFGAPSAPPRAQLRDLGRQPYEPVWRAMQAFTDGRDGDTPDELWLVEHDPVFTLGQAGKDEHVLMPGDIPVIHVDRGGQVTYHGPGQIVLYPLLDLRRLKVGVREYVDRIEQAVIDTLGEWNIEGARRDGAPGVYVAGAKVMALGIRVRRGCTFHGLAFNIAMDLSPYQRINPCGYQGLQVTSVLDLGGPSGMDQVKPVLVANIARQFGLSVEDAAPLNFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN33</accession>
    <name>A0A0S2DN33_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-acetylmuramoyl-L-alanine amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4698</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4698"/>
    <dbReference type="EnsemblBacteria" id="ALN60039">
        <property type="protein sequence ID" value="ALN60039"/>
        <property type="gene ID" value="GLE_4698"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4698"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4632"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06583">
        <property type="entry name" value="PGRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036505">
        <property type="entry name" value="Amidase/PGRP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002502">
        <property type="entry name" value="Amidase_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01510">
        <property type="entry name" value="Amidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00644">
        <property type="entry name" value="Ami_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55846">
        <property type="entry name" value="SSF55846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595869" evidence="1">
        <location>
            <begin position="24"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetylmuramoyl-L-alanine amidase" evidence="2">
        <location>
            <begin position="276"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="534" mass="57343" checksum="FA82EFBFA092F658" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNA8</accession>
    <name>A0A0S2DNA8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4286 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_23625</name>
        <name evidence="1" type="ORF">GLE_4862</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949371.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4862"/>
    <dbReference type="EnsemblBacteria" id="ALN60203">
        <property type="protein sequence ID" value="ALN60203"/>
        <property type="gene ID" value="GLE_4862"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4862"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4793"/>
    <dbReference type="OMA" id="EHAPKMR"/>
    <dbReference type="OrthoDB" id="1286390at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025563">
        <property type="entry name" value="DUF4286"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14114">
        <property type="entry name" value="DUF4286"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="108" mass="11943" checksum="AA0930EF77D29528" modified="2016-02-17" version="1">MHATADETIYEVSLDVDAAVAADFLAWLRGHIDEICALPGFLGADLHELADPAPAPGRLALCVRYRLRDAAALETYLRDHAPRMRAEGLARFGGRFDASRRVMRVLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNG9</accession>
    <name>A0A0S2DNG9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Pyruvate dehydrogenase E1 component</fullName>
            <ecNumber evidence="4 10">1.2.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">aceE</name>
        <name evidence="16" type="ORF">FE772_23205</name>
        <name evidence="15" type="ORF">GLE_4769</name>
    </gene>
    <organism evidence="15 17">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="15 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">C3</strain>
        </source>
    </reference>
    <reference evidence="16 18" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>(R)-N(6)-lipoyl-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + H(+) + pyruvate = (R)-N(6)-(S(8)-acetyldihydrolipoyl)-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + CO2</text>
            <dbReference type="Rhea" id="RHEA:19189"/>
            <dbReference type="Rhea" id="RHEA-COMP:10480"/>
            <dbReference type="Rhea" id="RHEA-COMP:10481"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="1.2.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).</text>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="4 10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949301.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4769"/>
    <dbReference type="EnsemblBacteria" id="ALN60110">
        <property type="protein sequence ID" value="ALN60110"/>
        <property type="gene ID" value="GLE_4769"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4769"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4704"/>
    <dbReference type="OMA" id="PDEYRTF"/>
    <dbReference type="OrthoDB" id="49937at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02017">
        <property type="entry name" value="TPP_E1_EcPDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035807">
        <property type="entry name" value="PDC_E1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004660">
        <property type="entry name" value="PDH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041621">
        <property type="entry name" value="PDH_E1_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43825:SF3">
        <property type="entry name" value="PTHR43825:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17831">
        <property type="entry name" value="PDH_E1_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000156">
        <property type="entry name" value="Pyruvate_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00759">
        <property type="entry name" value="aceE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10 15" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="TRANSKETOLASE_1" evidence="13">
        <location>
            <begin position="109"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="PDH_E1_M" evidence="14">
        <location>
            <begin position="498"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003157"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Feng T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <dbReference type="OMA" id="LQGREMP"/>
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    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
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    </dbReference>
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        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="12"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="195" mass="21189" checksum="47BE8966FC34C325" modified="2016-02-17" version="1">MTTAPAKRMSKADRREQLLETAMAMVREQGTDALSLGALAERAGVSKPIAYEHFGTRSGLLIALYRRIDERQAATAAQDFARTPKRLGDVARLMGASYMSCFRTAGPECHAIFAALKGDEEMERVQSELTAAYVEFYRGLLAPYAKVDDAELQRRCVAIVGAGEALSREMTHGRIDEADAAATMASLIEATLARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQK0</accession>
    <name>A0A0S2DQK0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_04830</name>
        <name evidence="3" type="ORF">FE772_25680</name>
        <name evidence="1" type="ORF">GLE_5312</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000009">
        <property type="protein sequence ID" value="OPD65068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949711.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000009.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60653">
        <property type="protein sequence ID" value="ALN60653"/>
        <property type="gene ID" value="GLE_5312"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65068">
        <property type="protein sequence ID" value="OPD65068"/>
        <property type="gene ID" value="BV903_04830"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5312"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5230"/>
    <dbReference type="OrthoDB" id="2043855at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD65068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="72" mass="7945" checksum="9A6153F8DDFF8F3B" modified="2016-02-17" version="1">MIFTVQLNESTYHGRTLSCDVADERFADAASASAAAKAEAFDLSMQLRVAVAIRIFEDSRIYLSHIMPAPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQP9</accession>
    <name>A0A0S2DQP9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_00095</name>
        <name evidence="3" type="ORF">GLE_5360</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949747.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60701">
        <property type="protein sequence ID" value="ALN60701"/>
        <property type="gene ID" value="GLE_5360"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5360"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5275"/>
    <dbReference type="OMA" id="TARYNGQ"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726697" evidence="2">
        <location>
            <begin position="21"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="179" mass="18262" checksum="3B43881928CE1E04" modified="2016-02-17" version="1">MRLMPLAAIASIVFLAACTAPDQNKDAAAPPPAEVAPAAGADAGAPPATDPAAPPSAKIGADQVGKLSPVPAFKGFGEHWSIDIQSTGEMNHKVDLTWGSGGEKASGTARYNGQPADAPSTLIVLSGELNTKDGAKPMTIEISRKECIDDGDNKHMQSVAVHVDGLDKFDGGCGDLAVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQR5</accession>
    <name>A0A0S2DQR5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase, short chain dehydrogenase/reductase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5227</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5227"/>
    <dbReference type="EnsemblBacteria" id="ALN60568">
        <property type="protein sequence ID" value="ALN60568"/>
        <property type="gene ID" value="GLE_5227"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5227"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5145"/>
    <dbReference type="OMA" id="YPDVPCK"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="329" mass="34304" checksum="469201CF2CDABC46" modified="2016-02-17" version="1">MKAPLVVLGATGGVGRGVVQAAIDSGRPVIAVARRSSELKALKAGYPQADLTVLAGSVANDAAGAKLARALRKLGRPFAGVVAAVCGSAERGRLLDSPAQFLRRKLDEDLLPHLAAARHLLPLLAESDRGGTYVLIGGPGSEHPWAGYGHRSIGAAALRMLARVLHDEARQQAVRVQLLAVDTPVCTEFNQRHSCPEWPSALSVGQRALALIDHDAGDEPPRPIVPYAVRAPGPALLPPRIRLPSPPASREHATPASSAPPATSQPATSPAPTSTNTVPKTVPLPAAAIATAQEPDCTSDDKTQRCLLDARALLKSLTAPNPKQEPTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DR50</accession>
    <name>A0A0S2DR50_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_5458</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60799">
        <property type="protein sequence ID" value="ALN60799"/>
        <property type="gene ID" value="GLE_5458"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5458"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5373"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="89" mass="9480" checksum="2450C949D7C5E983" modified="2016-02-17" version="1">MVAACAAPTGASDGSCASVGATRVATAKPQQRRRFRRRRDAAVAVRAIAAKAASGAAYWIRRSIDDLNSNRPLNSTLCVWGNTGRARFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA59</accession>
    <name>A0A0S2DA59_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATP-dependent DNA helicase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">DEAD/DEAH box helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_01330</name>
        <name evidence="4" type="ORF">GLE_0083</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
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</entry>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
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    <reference evidence="3 6" key="3">
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            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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        <source>
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    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="147" mass="16740" checksum="2BAD54AA7AAA6910" modified="2016-02-17" version="1">MTVLTLQWTFVEFEQYEAAEHEHSEIHVAAVTEQASFHTRLYVTRAQVRALASALRAWRLSGEAPHARWGEERGAMDIRFGFEPPGRVAIALRLRQRPIHTGFGVMADQVELYLASEPILIDHFADQLADMAEWKSRSAELQAAHFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    <reference evidence="18 20" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 20">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
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            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="14">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glutamate synthase family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="reaction ID" value="UER00089"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Glu_synthdom"/>
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        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Glu_syn_central"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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    <keyword evidence="8 17" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
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    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="16">
        <location>
            <begin position="31"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
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        </source>
    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ALN55431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="QCW24510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="1497" mass="163293" checksum="5A8F9AFB127407F8" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAN2</accession>
    <name>A0A0S2DAN2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribosomal large subunit pseudouridine synthase C</fullName>
            <ecNumber evidence="2">5.4.99.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rluC</name>
        <name evidence="2" type="ORF">GLE_0212</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.4.99.-" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0212"/>
    <dbReference type="EnsemblBacteria" id="ALN55571">
        <property type="protein sequence ID" value="ALN55571"/>
        <property type="gene ID" value="GLE_0212"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0212"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.214"/>
    <dbReference type="OMA" id="DRHETQF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
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        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="1">
        <location>
            <begin position="35"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="255" mass="27864" checksum="C8E5EDA19A1A35AF" modified="2016-02-17" version="1">MHPMFSSLIPHTDATATADAATAGGLPVLYADQALAIIDKPAGLMVHDSALARGETDFAADRLREQFGRPIFLVHRLDRATSGCLLLAFDRDTASALGKVLMSREVEKDYLAVCRGWPADDAFEVDHDLDGGPGKPLKKPAQTRFAVLARTELAIASAGFDTSRYALLRAQPLTGRFRQIRRHLKHLSHHLIGDTSHGDGRHNRSFRMLGIHRMLLHAQRLAFVHPHSGERIEAVAPADAEFAKALALFEGGEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBH6</accession>
    <name>A0A0S2DBH6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">O-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_03350</name>
        <name evidence="4" type="ORF">GLE_0526</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946097.1">
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_0526"/>
    <dbReference type="EnsemblBacteria" id="ALN55884">
        <property type="protein sequence ID" value="ALN55884"/>
        <property type="gene ID" value="GLE_0526"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0526"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
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        <property type="entry name" value="SAM_O-MeTrfase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
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    </dbReference>
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    </dbReference>
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    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN55884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW24851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="231" mass="25124" checksum="87CC29552402E928" modified="2016-02-17" version="1">MNTSAASRGAASTLTAAPLSALIQRLFDEADATSPMDLPEVAAMPRDEHERLMRSTTEYLDFYGRLKDMPLAVSRETGILLYQLARSTGARSIVEFGTSFGISTLHLAAALRDNGGGRLISSEFEPSKVERARANLAAGGLADLVEIREGDALRTFAADLPEWIDLVLLDGAKALYPRVLDLLEPRLRPGALIVADNADYSPDYLQRVRSPQRGYLSVPFGDDVELSMRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBJ4</accession>
    <name>A0A0S2DBJ4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbohydrate binding family 9 domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Membrane associated hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_03395</name>
        <name evidence="3" type="ORF">GLE_0536</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW24859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0536"/>
    <dbReference type="EnsemblBacteria" id="ALN55894">
        <property type="protein sequence ID" value="ALN55894"/>
        <property type="gene ID" value="GLE_0536"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0536"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.530"/>
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    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726636" evidence="1">
        <location>
            <begin position="23"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5916" evidence="2">
        <location>
            <begin position="259"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="740" mass="84329" checksum="A0C18AFE8D06C124" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBK0</accession>
    <name>A0A0S2DBK0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoribulokinase</fullName>
            <ecNumber evidence="3">2.7.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">prk</name>
        <name evidence="6" type="ORF">GLE_0539</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + D-ribulose 5-phosphate = ADP + D-ribulose 1,5-bisphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19365"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57870"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.19"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphoribulokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.19" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0539"/>
    <dbReference type="EnsemblBacteria" id="ALN55897">
        <property type="protein sequence ID" value="ALN55897"/>
        <property type="gene ID" value="GLE_0539"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0539"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.533"/>
    <dbReference type="OMA" id="WNGQTDI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008974">
        <property type="term" value="F:phosphoribulokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006082">
        <property type="entry name" value="PRK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PHRIBLKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="158"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="217"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="262"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="331"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="5">
        <location>
            <begin position="410"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN55897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="704" mass="78327" checksum="2E76A7DCC937E237" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBK1</accession>
    <name>A0A0S2DBK1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lanthionine synthetase C-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0558</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946123.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0558"/>
    <dbReference type="EnsemblBacteria" id="ALN55916">
        <property type="protein sequence ID" value="ALN55916"/>
        <property type="gene ID" value="GLE_0558"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0558"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.552"/>
    <dbReference type="OMA" id="MIAWCHG"/>
    <dbReference type="OrthoDB" id="50133at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04792">
        <property type="entry name" value="LanM-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007822">
        <property type="entry name" value="LANC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025410">
        <property type="entry name" value="Lant_dehyd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017146">
        <property type="entry name" value="Lanti_2_LanM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13575">
        <property type="entry name" value="DUF4135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05147">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037228">
        <property type="entry name" value="Lant_mod_RumM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01950">
        <property type="entry name" value="LANCSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM01260">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03897">
        <property type="entry name" value="lanti_2_LanM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4135" evidence="1">
        <location>
            <begin position="104"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="954" mass="103336" checksum="73DF441987C662D2" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC15</accession>
    <name>A0A0S2DC15_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">GtrA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FE772_04140</name>
        <name evidence="8" type="ORF">GLE_0691</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GtrA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946220.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0691"/>
    <dbReference type="EnsemblBacteria" id="ALN56049">
        <property type="protein sequence ID" value="ALN56049"/>
        <property type="gene ID" value="GLE_0691"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0691"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.679"/>
    <dbReference type="OMA" id="QYTWLAK"/>
    <dbReference type="OrthoDB" id="1813832at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007267">
        <property type="entry name" value="GtrA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04138">
        <property type="entry name" value="GtrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="GtrA" evidence="7">
        <location>
            <begin position="10"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN56049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW24982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="127" mass="14117" checksum="2E98CF01F168B4E7" modified="2016-02-17" version="1">MSLTRQGRNYLIFGAIQYCVDWGMMVGLSHMGMPVEAANLAGRVSGALLGFWLNGRFTFNGEDSALGRRQFGRFVALWIGSTVLSTVAISLVDTHAGLKWTWLAKPVIELALAVVGFTLSRYWVYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCA5</accession>
    <name>A0A0S2DCA5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">3-deoxy-D-manno-octulosonic acid transferase</fullName>
            <shortName evidence="9">Kdo transferase</shortName>
            <ecNumber evidence="3 9">2.4.99.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 9">Lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">waaA</name>
        <name evidence="12" type="ORF">BV903_09505</name>
        <name evidence="11" type="ORF">GLE_0803</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">B25</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>CMP-3-deoxy-beta-D-manno-octulosonate + lipid IVA (E. coli) = alpha-Kdo-(2-&gt;6)-lipid IVA + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28066"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58603"/>
            <dbReference type="ChEBI" id="CHEBI:60364"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:85987"/>
            <dbReference type="EC" id="2.4.99.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Bacterial outer membrane biogenesis; LPS core biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the glycosyltransferase group 1 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.12" evidence="3 9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000021">
        <property type="protein sequence ID" value="OPD64116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946308.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0803"/>
    <dbReference type="EnsemblBacteria" id="ALN56161">
        <property type="protein sequence ID" value="ALN56161"/>
        <property type="gene ID" value="GLE_0803"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64116">
        <property type="protein sequence ID" value="OPD64116"/>
        <property type="gene ID" value="BV903_09505"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0803"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.792"/>
    <dbReference type="OMA" id="FIKYEFW"/>
    <dbReference type="OrthoDB" id="1163086at2"/>
    <dbReference type="UniPathway" id="UPA00958"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043842">
        <property type="term" value="F:Kdo transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009244">
        <property type="term" value="P:lipopolysaccharide core region biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11720">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007507">
        <property type="entry name" value="Glycos_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038107">
        <property type="entry name" value="Glycos_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039901">
        <property type="entry name" value="Kdotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42755">
        <property type="entry name" value="PTHR42755"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04413">
        <property type="entry name" value="Glycos_transf_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_N" evidence="10">
        <location>
            <begin position="42"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR639901-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR639901-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN56161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OPD64116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="431" mass="47901" checksum="59F2A44B641789CC" modified="2016-02-17" version="1">MRKDLIERLLRGLYSVALYLLAPVTVYHLIWRGFRQPAYFRGWLERYAVYRGPAQTRTLWLHAVSVGEVNAAIPLVNALRRGRPDLRLLVTTITPTGADRARAAWSDSVEHVYLPYDLPGAVGRFLKHHQPCAALIMETELWPNLLFGCRDRGIPAYILNARLSERSLRGYRVLAPLVSRALRTVRTVAAQSHADGQRFVELGADPRQVVETGNLKFDVSVPDALEDFAQECHRHTGERPVWIAASTHEDEEAVTVAMHRHLRERFPGLLLLWAPRHPERFRVVAENARSAGWQVSTRSRARWPQPGDDVFVIDTLGELMSFYACADVAFVGGSLQPIGGHNLLEPAATGTAIVTGPHLHNFVEIAQRLDDAGALRIGQDAEQVEAAVERLLADPAERAQMVAAGRALVETGRGALARTMALLQPALPPRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCM4</accession>
    <name>A0A0S2DCM4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0918</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0918"/>
    <dbReference type="EnsemblBacteria" id="ALN56276">
        <property type="protein sequence ID" value="ALN56276"/>
        <property type="gene ID" value="GLE_0918"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0918"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.906"/>
    <dbReference type="OMA" id="NCAHCHN"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022269">
        <property type="entry name" value="CHP03806_HNE0200"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03806">
        <property type="entry name" value="chp_HNE_0200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594977" evidence="1">
        <location>
            <begin position="22"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="397" mass="43167" checksum="15D07CDDECC2ECD3" modified="2016-02-17" version="1">MSMRCVVAVLLSLLVAGCSKPQEPAPAAQGAVPAAPAALAADAPWAPVRFFADGQPESLADWNLLRVAGGRLQLNREVLPYDLNTALFSDYAHKLRTVWMPKGQAANYAADEEFDFPVGTVFSKTFYYPRGEGEAVLRSYDEGPDLRGGGLEMSKVRLIETRLLLRRQDGWVALPYVWNREQTGAKLMRGGELVSLELVAADGGRESADYAVPDQNQCAGCHGTDMKSKALHPIGPKARHLNRDFAYPDDGLQNQIARWTRAGYLQGAPAPQQAPRDANWRDPAAPLDARARAYLDINCGHCHSPKGPGNTSGLWLNAATQEPLRLGRCKLPIAAGHGTGDHRYGVVPGKPDESILVYRMRSGDPSVMMPELGRSVVHEEGVQLIRDWIAAQQGQCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCM6</accession>
    <name>A0A0S2DCM6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pilus assembly protein PilM</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Type IV pilus assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pilM</name>
        <name evidence="2" type="ORF">BV903_12290</name>
        <name evidence="4" type="ORF">D9T17_22620</name>
        <name evidence="3" type="ORF">FE772_05300</name>
        <name evidence="1" type="ORF">GLE_0932</name>
    </gene>
    <organism evidence="1 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 5">C3</strain>
        </source>
    </reference>
    <reference evidence="2 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">OH11</strain>
        </source>
    </reference>
    <reference evidence="3 8" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000030">
        <property type="protein sequence ID" value="OPD63600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000056">
        <property type="protein sequence ID" value="ROU04644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946404.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000056.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0932"/>
    <dbReference type="EnsemblBacteria" id="ALN56290">
        <property type="protein sequence ID" value="ALN56290"/>
        <property type="gene ID" value="GLE_0932"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63600">
        <property type="protein sequence ID" value="OPD63600"/>
        <property type="gene ID" value="BV903_12290"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0932"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.920"/>
    <dbReference type="OMA" id="EKVQDRQ"/>
    <dbReference type="OrthoDB" id="1750212at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005883">
        <property type="entry name" value="PilM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11104">
        <property type="entry name" value="PilM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019169">
        <property type="entry name" value="PilM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01175">
        <property type="entry name" value="pilM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD63600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROU04644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="352" mass="37713" checksum="66E4A3AE035ECC79" modified="2016-02-17" version="1">MGLITKSQPALVGVDISSTAVKLLQLSRAGNRYRVEHYAVEPLPPNAVVEKNIVEVEAVGEAIKRAVARSGTRAKHAAAAVAGSSVITRVIGMPADLDEDDLESQVELEAANYVPYPIDEVNHDFEVLGPMPGSPDMIQVLLAASRSENVEVRASALELGGLTPRVMDVEAFAIENAFALLADTLSGPRDGLVALVDSGATMTTLNVLRNGRSLYHREQVFGGKQLTDEVMRRYGLSYEEAGLAKRQGGLPESYQAEVLEPFKEAMVQQVSRLLQFFYAGSEFNRVDQIVLAGGGASIPRIAEMVEEQLGIPTTVANPLAHMTLGPRVQAHALAQDAPALMIACGLALRSFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCP8</accession>
    <name>A0A0S2DCP8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Co-chaperonin GroES</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">10 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Chaperonin-10</fullName>
            <shortName evidence="3">Cpn10</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">groS</name>
        <name evidence="3 6" type="synonym">groES</name>
        <name evidence="8" type="ORF">D9T17_23250</name>
        <name evidence="7" type="ORF">FE772_04610</name>
        <name evidence="5" type="ORF">GLE_0783</name>
        <name evidence="6" type="ORF">LEN_4159</name>
        <name evidence="9" type="ORF">SAMN05421681_1126</name>
    </gene>
    <organism evidence="5 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 10">C3</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2016" name="DNA Res." volume="0" first="0" last="0">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer, Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M497-1</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="3">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">ATCC 29487</strain>
        </source>
    </reference>
    <reference evidence="6 12" key="4">
        <citation type="journal article" date="2017" name="DNA Res." volume="24" first="169" last="177">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
            <dbReference type="PubMed" id="28065880"/>
            <dbReference type="DOI" id=".1093/dnares/dsw055"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 12">M497-1</strain>
        </source>
    </reference>
    <reference evidence="8 13" key="5">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 13">OH11</strain>
        </source>
    </reference>
    <reference evidence="7 14" key="6">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <source>
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        </source>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="612" mass="68293" checksum="7DD0E638A982940D" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD07</accession>
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        <submittedName>
            <fullName evidence="3">Diguanylate cyclase</fullName>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">C3</strain>
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        </source>
    </evidence>
    <sequence length="379" mass="41847" checksum="1CC1E33B540E7549" modified="2016-02-17" version="1">MYQGVGGRMRSVLIALLARPDEIMLEIGAGGELLVARLRAVLAAMLLLLPLFNALGGGSVKETLIGLGGAVFVNVFSQLWLALARRQRRYRWLPFCTAAFDVTATTAVLAMLAVQHLPAGLNSLIVWCGYLLAILMTALRSDGRVTLFSGVLALLQYGLLVLWVFAAAGSPEDLMSSDYGAVTVGSQTQRLLLLAMMTLATSMVVYRMQRLIEMSGTDGLTRLPNRTWLTHRIPRLFDAVRRDGGSLTLALIDLDHFKRINDDYGHRLGDRSLRHLVAVLREQAEPSEWLVRLSGGEFLLVMRKPLGTAFEEVDAIRRTVAERPFEPGRGAEPLWLSFSAGLVTFPQEGGDLSRLLRRADLRLQRAKQSGRNRVVARDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD36</accession>
    <name>A0A0S2DD36_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">dITP/XTP pyrophosphatase</fullName>
            <ecNumber evidence="7">3.6.1.66</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Non-canonical purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Non-standard purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Nucleoside-triphosphate diphosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Nucleoside-triphosphate pyrophosphatase</fullName>
            <shortName evidence="7">NTPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rdgB</name>
        <name evidence="10" type="ORF">FE772_05185</name>
        <name evidence="9" type="ORF">GLE_0906</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>H2O + ITP = diphosphate + H(+) + IMP</text>
            <dbReference type="Rhea" id="RHEA:29399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>H2O + XTP = diphosphate + H(+) + XMP</text>
            <dbReference type="Rhea" id="RHEA:28610"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:61314"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>dITP + H2O = dIMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28342"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61194"/>
            <dbReference type="ChEBI" id="CHEBI:61382"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the HAM1 NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.66" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946384.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0906"/>
    <dbReference type="EnsemblBacteria" id="ALN56264">
        <property type="protein sequence ID" value="ALN56264"/>
        <property type="gene ID" value="GLE_0906"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0906"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.894"/>
    <dbReference type="OMA" id="DCFADDT"/>
    <dbReference type="OrthoDB" id="1824064at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035870">
        <property type="term" value="F:dITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:nucleoside-triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036222">
        <property type="term" value="F:XTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009146">
        <property type="term" value="P:purine nucleoside triphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00515">
        <property type="entry name" value="HAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01405">
        <property type="entry name" value="Non_canon_purine_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020922">
        <property type="entry name" value="dITP/XTP_pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002637">
        <property type="entry name" value="Ham1p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067">
        <property type="entry name" value="PTHR11067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01725">
        <property type="entry name" value="Ham1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00042">
        <property type="entry name" value="TIGR00042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="7"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="181"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW25148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="198" mass="21203" checksum="BF41A1BEF901A0A7" modified="2016-02-17" version="1">MKLVLASSNAGKLVELRDLLGATGIELVAQSDLGVEDIEETGSTFVENALLKARHASAVTGLPALADDSGICVDALGGAPGLYSARYSGRHGDNEGNIDKLLAALKDVPDERRGAHFYAVIVALRHAGDPRPIIAEGVWNGRILHRRQGSRGFGYQPVFLDTEHNISAGEIDDALKNRVSHRARALAALRERLPELAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD44</accession>
    <name>A0A0S2DD44_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(P)H dehydrogenase (quinone)</fullName>
            <ecNumber evidence="4">1.6.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">NAD(P)H:quinone oxidoreductase</fullName>
            <shortName evidence="4">NQO</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">wrbA</name>
        <name evidence="7" type="ORF">BV903_03990</name>
        <name evidence="8" type="ORF">FE772_06010</name>
        <name evidence="6" type="ORF">GLE_1091</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">C3</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a quinone + H(+) + NADH = a quinol + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:46160"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.6.5.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a quinone + H(+) + NADPH = a quinol + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:46164"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.6.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="4">Binds 1 FMN per monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the WrbA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.6.5.2" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000007">
        <property type="protein sequence ID" value="OPD65261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946518.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1091"/>
    <dbReference type="EnsemblBacteria" id="ALN56449">
        <property type="protein sequence ID" value="ALN56449"/>
        <property type="gene ID" value="GLE_1091"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65261">
        <property type="protein sequence ID" value="OPD65261"/>
        <property type="gene ID" value="BV903_03990"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1091"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1078"/>
    <dbReference type="OMA" id="LHFGMVI"/>
    <dbReference type="OrthoDB" id="796211at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003955">
        <property type="term" value="F:NAD(P)H dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01017">
        <property type="entry name" value="NQOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010089">
        <property type="entry name" value="Flavoprotein_WrbA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037513">
        <property type="entry name" value="NQO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01755">
        <property type="entry name" value="flav_wrbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 4" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="5">
        <location>
            <begin position="4"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="78"/>
            <end position="80"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN56449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD65261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW25282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="199" mass="21233" checksum="D6B88E7280AE33D5" modified="2016-02-17" version="1">MAKVLVLYYSAYGHCEKMAEAVAEGAREAGAQVDIKRVPELVPEEVARKSHYKLDQAAPVAQIADLEHYDAIVVGTGTRFGRMSSQMANFLDQAGGLWAKGALHGKVGAAFTSTATQHGGQETTLFSIITNLLHFGMVIVGLNYGYAGQMRLDEVTGGSPYGTTTITGGDGSRQPTQNELDAARYQGREVAETAKKLHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDB1</accession>
    <name>A0A0S2DDB1_LYSEN</name>
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        <submittedName>
            <fullName evidence="4">Glycosyl transferase, group 2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_1110</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
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    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    <dbReference type="EnsemblBacteria" id="ALN56468">
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    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1110"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
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            <begin position="270"/>
            <end position="295"/>
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        <location>
            <begin position="11"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="350" mass="38146" checksum="7AFE34110B8662B8" modified="2016-02-17" version="1">MRGMNRERVTVVLAAFDEAQSLPLLQPRIAAALDALAADGVDGQVLYVDDGSRDATWAILQGFAAADPRVGLLRLSRNFGKEAALTAGLDLVETGAALILDADGQDPPELIPQFVAKWREGYDDVYGTRLEREGEGWFKRSSAHAFYRVIGRLSRTPIPADTGDFRLLSPRALAALRQLRERHRFMKGLFGWVGYNRIGLPYHRGARAAGRSKFNFWRLWNLALEGITSFSTAPLRLATYLGLATAALAFAFALKVVLKALLFGDPVQGWPTMMAVILFLGGVQLIALGLIGEYLGRLYEESKQRPLYLVDTFRPAAGVSSGQTPLSTFPTLAQGDGRAHSKAAVGDESP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDM6</accession>
    <name>A0A0S2DDM6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein YebE</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Tellurite resistance TerB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_20770</name>
        <name evidence="4" type="ORF">FE772_06875</name>
        <name evidence="2" type="ORF">GLE_1276</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000064">
        <property type="protein sequence ID" value="OPD61996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946650.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000064.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1276"/>
    <dbReference type="EnsemblBacteria" id="ALN56633">
        <property type="protein sequence ID" value="ALN56633"/>
        <property type="gene ID" value="GLE_1276"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61996">
        <property type="protein sequence ID" value="OPD61996"/>
        <property type="gene ID" value="BV903_20770"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1276"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1259"/>
    <dbReference type="OMA" id="EMAAEMY"/>
    <dbReference type="OrthoDB" id="1281424at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd07178">
        <property type="entry name" value="terB_like_YebE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029024">
        <property type="entry name" value="TerB-like"/>
    </dbReference>
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        <property type="entry name" value="YebE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04391">
        <property type="entry name" value="DUF533"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF158682"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="244" mass="26203" checksum="04BBF12E5B4AF645" modified="2016-02-17" version="1">MKTQGFLDQLLKTAQNSLGGGGGLGDLLGGGKPLARTEPQRGHERRDEPSRGLLNADFGKGALAGGALGLLLGNKKLRKHAGKFALAGGVAAVGVLAYKAYGDYKRQQEGPGAAEPRTVDRLPPPQAEQHSRAILQALVAASKADGHIDAREREAIEGEFVRIDGDTQLRTWLHAELEKPLDPAEVARAAETPEIGAEMYLASLLAADEQNYMERAYLDELARQLKIDDALKARLEQQLRDAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDP4</accession>
    <name>A0A0S2DDP4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1082</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56440">
        <property type="protein sequence ID" value="ALN56440"/>
        <property type="gene ID" value="GLE_1082"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1082"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1069"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="70" mass="7072" checksum="ADF8024281A0E57F" modified="2016-02-17" version="1">MACGAHRATVSAGARANAPNIGAWRGGAAFPAGRSGASRDRGVAGRVAYAVSRSRLAPLLQGDTRPAARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE30</accession>
    <name>A0A0S2DE30_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1266</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946641.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1266"/>
    <dbReference type="EnsemblBacteria" id="ALN56623">
        <property type="protein sequence ID" value="ALN56623"/>
        <property type="gene ID" value="GLE_1266"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1266"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1250"/>
    <dbReference type="OrthoDB" id="120742at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045670">
        <property type="entry name" value="DUF5916"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19313">
        <property type="entry name" value="DUF5916"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595005" evidence="1">
        <location>
            <begin position="26"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5916" evidence="2">
        <location>
            <begin position="223"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5916" evidence="2">
        <location>
            <begin position="379"/>
            <end position="749"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="753" mass="84498" checksum="0D01538FE4CDB93C" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEL3</accession>
    <name>A0A0S2DEL3_LYSEN</name>
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        <submittedName>
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        </submittedName>
        <submittedName>
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        </submittedName>
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        <name evidence="6" type="ORF">FE772_08395</name>
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        <name type="scientific">Lysobacter enzymogenes</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
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        <text evidence="1 2">Belongs to the pirin family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN56972">
        <property type="protein sequence ID" value="ALN56972"/>
        <property type="gene ID" value="GLE_1615"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1615"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1595"/>
    <dbReference type="OMA" id="RPHPHIN"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Pirin"/>
    </dbReference>
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        <property type="entry name" value="Pirin_C_dom"/>
    </dbReference>
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        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
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        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
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        <property type="entry name" value="PTHR13903"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="120"/>
        </location>
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        <location>
            <begin position="173"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW25683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="286" mass="31418" checksum="5410A2369FF09FC8" modified="2016-02-17" version="1">MTTIVAPRVHDLGGFQVRRAVPSLQARSVGPFVFVDHMGPAEFAPGQGIDVRPHPHIGLATVTFLWAGAIGHRDTLGSVQDIHPGDVNWMTAGRGIAHSERTPDAPRAVGQAVHGLQTWVALPRSFEETAPAFHHHPAATLPQQRRDGAWLRIVAGRGFGEESPVRVFADTLYVAIDLDPGSELDIEDSHAERALYVLEGESQLDGADLPEKHLVVLDPGTRPRLRAKTPLKAMLLGGEPLDGPRHLWWNFVSSSRERIEQAKQDWAEGRFGQIPGEHEFIPLPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DER7</accession>
    <name>A0A0S2DER7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">BV903_07130</name>
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        <name evidence="1" type="ORF">GLE_1663</name>
    </gene>
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        </lineage>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000013">
        <property type="protein sequence ID" value="OPD64656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946957.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1663"/>
    <dbReference type="EnsemblBacteria" id="ALN57020">
        <property type="protein sequence ID" value="ALN57020"/>
        <property type="gene ID" value="GLE_1663"/>
    </dbReference>
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        <property type="gene ID" value="BV903_07130"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046163">
        <property type="entry name" value="DUF6165"/>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD64656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="134" mass="15349" checksum="AA2B808BE990AE86" modified="2016-02-17" version="1">MSEILVPVSFGELLDKIAILQIKSERMSDEAKLANVRAELTALERTWMAHPAAGNDIVRLRAELKAVNERLWVIEDDIRVKEKRQEFDAEFIRLARSVYVENDVRARVKKEINLALGSTYVEEKSYQDYGTGPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF05</accession>
    <name>A0A0S2DF05_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DUF4190 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_13490</name>
        <name evidence="5" type="ORF">FE772_09065</name>
        <name evidence="3" type="ORF">GLE_1761</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ALN57116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD63437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW25794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947032.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1761"/>
    <dbReference type="EnsemblBacteria" id="ALN57116">
        <property type="protein sequence ID" value="ALN57116"/>
        <property type="gene ID" value="GLE_1761"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63437">
        <property type="protein sequence ID" value="OPD63437"/>
        <property type="gene ID" value="BV903_13490"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1761"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1737"/>
    <dbReference type="OMA" id="SICAIIT"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="DUF4190"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4190" evidence="2">
        <location>
            <begin position="11"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD63437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="96" mass="9954" checksum="97206252EB919D38" modified="2016-02-17" version="1">MQVPARETNVLAILSLIAGILGWTLLPVLGSLAAIVTGHIARGQIRREPQRYDGAGLAIGGLILGWSSVIIAVLTVVVIVLFFGGIAALLAFSGQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFB4</accession>
    <name>A0A0S2DFB4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase, group 2 family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_09610</name>
        <name evidence="2" type="ORF">GLE_1876</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1876"/>
    <dbReference type="EnsemblBacteria" id="ALN57228">
        <property type="protein sequence ID" value="ALN57228"/>
        <property type="gene ID" value="GLE_1876"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1876"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1847"/>
    <dbReference type="OMA" id="SAIVPEY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="427"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="460"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="496" mass="55346" checksum="680FB5158A416A6E" modified="2016-02-17" version="1">MQRMHDARESFHPQAFPHRSRFVRFACPLQHLACGSASRGPYRRVRSAKPDPCETQRRARQRRAVAFAFAGCARPMPNTFVPDRPGFGRFVLDALALDHLVLSQFVLTGVVGFSTLILFACLLFLAGWACWRRLRQPPPRALARYPFVSILVPFYNEPERSLLCTLESIERSEYPGPVEVLLVDDGSTNATAAAVAQWLAQPRGKRYEFIARERNGGAKGLALDAALPRLSPDSDVVTVIDSDTVIAPGALRSAVEALYASPRHAAACGLIVPAGRHQSWLHRLQFYEHIGALAAIRYVQSKLGSVNVVAGAFSLHRTQVIRELGGWGEWLVEDIAWTWRALAHGYSIAYAPDAIAYTICPTTLMGLFRQRRRWARGRLESFRVAWGISWARTMKMLPWWLLWAQSALAPTLLLLIAGALFYRSHALLAVAALNWLLMAALNFVSVLHARERLQLGLTDLLLVSVYNTVIDALLLPANLIGLLDELRGGRKSWMTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFG6</accession>
    <name>A0A0S2DFG6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1907</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57258">
        <property type="protein sequence ID" value="ALN57258"/>
        <property type="gene ID" value="GLE_1907"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1907"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1875"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="56" mass="6267" checksum="08EF3AF49831AC55" modified="2016-02-17" version="1">MDTDNVPHVGYDTLPLVVPAKAGIHFALAQHRQRTSASLEKIEPEQQRNGFRLSPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFL6</accession>
    <name>A0A0S2DFL6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57380">
        <property type="protein sequence ID" value="ALN57380"/>
        <property type="gene ID" value="GLE_2030"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2030"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1995"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594764" evidence="1">
        <location>
            <begin position="21"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="268" mass="29014" checksum="2AE11DFFBBAA1F05" modified="2016-02-17" version="1">MRQSAIAAMACFALAWPALGAAGAHGISLGAGEVPKGWAAIAAPEDAAQWQCAIDALRPWQVSADDGERVRIAPPQPAPPLQVALADGVMRAAGDGRIEWTPRQGAAAKAGFVLSNADLRPRAATEFGGDVFLAEGRSHDGRHEGAIVRFERRDAQRWRIHRALELDATPAAAARSGERDWVVLTQTGLVAIDLAAQRQRPLHRNPRWARLQPQSLQASGAGWLIGTAHGLIRLQPFGEHYSEQWLVPENCRRLAAPQCGCRPQRLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFR6</accession>
    <name>A0A0S2DFR6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hydroxymethylglutaryl-CoA lyase</fullName>
            <ecNumber evidence="4">4.1.3.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mvaB</name>
        <name evidence="5" type="ORF">FE772_09910</name>
        <name evidence="4" type="ORF">GLE_1948</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HMG-CoA lyase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.4" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947164.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1948"/>
    <dbReference type="EnsemblBacteria" id="ALN57299">
        <property type="protein sequence ID" value="ALN57299"/>
        <property type="gene ID" value="GLE_1948"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1948"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1913"/>
    <dbReference type="OMA" id="FGGCPMA"/>
    <dbReference type="OrthoDB" id="1111394at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004419">
        <property type="term" value="F:hydroxymethylglutaryl-CoA lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043594">
        <property type="entry name" value="HMGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42738">
        <property type="entry name" value="PTHR42738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="3">
        <location>
            <begin position="11"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="303" mass="31261" checksum="7CA88D4CC6093F45" modified="2016-02-17" version="1">MNQPATPPASVRIVEVGPRDGLQNEKAQIATADKIALIDRLSATGLRSIEATSFVSPKWVPQLADAAEVFAGIARRPGVHYPVLVPNEQGYERARAVGVEEIAVFTAASEAFNRKNINASIDESLARFAPVMARAKADGVAVRGYVSTVLGCPYQGAVPVGDVVRVARALFDMGCYEISLGDTIGVGTPGKARAMFKAVAAEVPLTALAVHFHDTYGQALANILACLEEGAAVVDSAVSGTGGCPYAKGASGNVASEDVVYMLHGLGVSTGVDIDALADTGRWLAALLGRETGSKVGKALAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFU4</accession>
    <name>A0A0S2DFU4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription elongation factor GreB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Transcript cleavage factor GreB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 8" type="primary">greB</name>
        <name evidence="8" type="ORF">FE772_10740</name>
        <name evidence="7" type="ORF">GLE_2126</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the GreA/GreB family. GreB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947299.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2126"/>
    <dbReference type="EnsemblBacteria" id="ALN57476">
        <property type="protein sequence ID" value="ALN57476"/>
        <property type="gene ID" value="GLE_2126"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2126"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2090"/>
    <dbReference type="OMA" id="DQIFFGA"/>
    <dbReference type="OrthoDB" id="1591985at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00105">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00930">
        <property type="entry name" value="GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036953">
        <property type="entry name" value="GreA/GreB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018151">
        <property type="entry name" value="TF_GreA/GreB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028624">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001437">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_C"/>
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    </dbReference>
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    </dbReference>
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        <location>
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        <location>
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        <source>
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        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
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        <source>
            <dbReference type="Pfam" id="PF01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW26074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="170" mass="19139" checksum="0BF004F149CB6687" modified="2016-02-17" version="1">MGRWRPPAEHSTALITREGHARLKHELDELWRLRRPEVVKALAAAAAEGDRSENAEYTYRKKQLAEIDRRVRYLSKRLPLLRVIESTPSDPQSVFFGAWVEVEDVASGELARYRIVGPDETDARLGHISIDSPLARAMLKRRVDDEFEAVLPAGPARFAIVEVSYAPPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG09</accession>
    <name>A0A0S2DG09_LYSEN</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_10840</name>
        <name evidence="3" type="ORF">FE772_09955</name>
        <name evidence="1" type="ORF">GLE_1959</name>
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        <name type="scientific">Lysobacter enzymogenes</name>
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        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947170.1">
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    <dbReference type="EnsemblBacteria" id="ALN57310">
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        <property type="gene ID" value="GLE_1959"/>
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        <property type="gene ID" value="BV903_10840"/>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="EMBL" id="OPD63894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25940.1"/>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="179" mass="20413" checksum="AFA5FFF8F730617C" modified="2016-02-17" version="1">MSEPASLYARFTLSHEQYEAFMNSAPARPAGFADWQSWFDRREMSGGSRVPPEILADLDAASVAEVIKAWREDAWTGTPPVEYDEIRRTLRIAMLQASENYHEMLRLLTPLRGAARFNEPGADDFVVILDFLWDEQAIEAYVRFGDGGSRFDEDCAPEHLEEARTYLREALDYLQSRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN57593">
        <property type="protein sequence ID" value="ALN57593"/>
        <property type="gene ID" value="GLE_2244"/>
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    <dbReference type="KEGG" id="lez:GLE_2244"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2209"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="GlmS_trans"/>
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        <property type="entry name" value="Ntn_hydrolases_N"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937:SF0">
        <property type="entry name" value="PTHR10937:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="1">
        <location>
            <begin position="2"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="548" mass="59760" checksum="CE7509033302CDDD" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGG0</accession>
    <name>A0A0S2DGG0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">UDP-N-acetylglucosamine 2-epimerase</fullName>
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        </submittedName>
        <submittedName>
            <fullName evidence="11">UDP-N-acetylglucosamine 2-epimerase (Non-hydrolyzing)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FE772_11370</name>
        <name evidence="10" type="ORF">GLE_2255</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UDP-N-acetylglucosamine 2-epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.14" evidence="10 11"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2255"/>
    <dbReference type="EnsemblBacteria" id="ALN57604">
        <property type="protein sequence ID" value="ALN57604"/>
        <property type="gene ID" value="GLE_2255"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2255"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2220"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008963">
        <property type="term" value="F:phospho-N-acetylmuramoyl-pentapeptide-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008761">
        <property type="term" value="F:UDP-N-acetylglucosamine 2-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003331">
        <property type="entry name" value="UDP_GlcNAc_Epimerase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029767">
        <property type="entry name" value="WecB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43174">
        <property type="entry name" value="PTHR43174"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02350">
        <property type="entry name" value="Epimerase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00236">
        <property type="entry name" value="wecB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="322"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="Epimerase_2" evidence="9">
        <location>
            <begin position="440"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN57604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW26183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="799" mass="86206" checksum="7327AF71F9AA509C" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGI5</accession>
    <name>A0A0S2DGI5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent outer membrane receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLE_2269</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947412.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2269"/>
    <dbReference type="EnsemblBacteria" id="ALN57618">
        <property type="protein sequence ID" value="ALN57618"/>
        <property type="gene ID" value="GLE_2269"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2269"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2234"/>
    <dbReference type="OMA" id="GVEFKIP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595135" evidence="6">
        <location>
            <begin position="28"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="80"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="7">
        <location>
            <begin position="386"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="826"/>
            <end position="845"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN57618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="977" mass="106910" checksum="C1B7D018D33902B7" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGI7</accession>
    <name>A0A0S2DGI7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphotransferase enzyme family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Phosphotransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_11775</name>
        <name evidence="2" type="ORF">GLE_2348</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947470.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2348"/>
    <dbReference type="EnsemblBacteria" id="ALN57697">
        <property type="protein sequence ID" value="ALN57697"/>
        <property type="gene ID" value="GLE_2348"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2348"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2310"/>
    <dbReference type="OMA" id="FVDYYAE"/>
    <dbReference type="OrthoDB" id="1457558at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05154">
        <property type="entry name" value="ACAD10_11_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041726">
        <property type="entry name" value="ACAD10_11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="40"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="358" mass="41189" checksum="0AF0AAAA3D34AA46" modified="2016-02-17" version="1">MSAAFRDDARPVRAGEELDAAAVDAWLKPRLPHLQGTPEIAQYAGGASNWTYRLRYANDDLILRRPPAGKKAKSAHDMGREFRIQQALRPVFEFVPRMHAHCDDDSVIGAEFYVMQRLDGLILRKNPPAGFDLSRERVAALAHNVLDTLVALHQVDYRAAGLDGLAPGAGYAQRQIAGWSKRYGDARTWNVPRGGKIMAWLRENLPQEEIIRLTHNDFRFDNVVLDRDDPTRVIGVLDWELATLGDPLMDVGNLLAYWVQADDDFIARDTRRQPTHLAGMPSRREVMDYYSQRTGWRPRSWAFYEVYGLFRLSAIAQQIYYRYHHGQTRNPAFKRFWLSVNYLHWRCRRAIARAERGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGJ8</accession>
    <name>A0A0S2DGJ8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2285</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57634">
        <property type="protein sequence ID" value="ALN57634"/>
        <property type="gene ID" value="GLE_2285"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2285"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2250"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="41" mass="4854" checksum="4930513999750AAF" modified="2016-02-17" version="1">MGKPRTVQTHRDPLFNRCRFSVRLPRSAPAYGVFSRLEHRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGQ2</accession>
    <name>A0A0S2DGQ2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Carbamoyl-phosphate synthase large chain</fullName>
            <ecNumber evidence="13">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Carbamoyl-phosphate synthetase ammonia chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 17" type="primary">carB</name>
        <name evidence="18" type="ORF">FE772_11285</name>
        <name evidence="17" type="ORF">GLE_2238</name>
    </gene>
    <organism evidence="17 19">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="17 19" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">C3</strain>
        </source>
    </reference>
    <reference evidence="18 20" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 20">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="13">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="13">Binds 4 Mg(2+) or Mn(2+) ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="13">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the CarB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.5" evidence="13"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947390.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2238"/>
    <dbReference type="EnsemblBacteria" id="ALN57587">
        <property type="protein sequence ID" value="ALN57587"/>
        <property type="gene ID" value="GLE_2238"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2238"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2203"/>
    <dbReference type="OMA" id="IEPAGIH"/>
    <dbReference type="OrthoDB" id="48855at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00171"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01424">
        <property type="entry name" value="MGS_CPS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01210_A">
        <property type="entry name" value="CPSase_L_chain_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01210_B">
        <property type="entry name" value="CPSase_L_chain_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006275">
        <property type="entry name" value="CarbamoylP_synth_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005480">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo"/>
    </dbReference>
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        <property type="entry name" value="CarbamoylP_synth_lsu_oligo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005483">
        <property type="entry name" value="CbamoylP_synth_lsu_CPSase_dom"/>
    </dbReference>
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        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033937">
        <property type="entry name" value="MGS_CPS_CarB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02787">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00098">
        <property type="entry name" value="CPSASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01096">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF48108"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52335"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01369">
        <property type="entry name" value="CPSaseII_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="13" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="9 13 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13 17" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0464">Manganese</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 13 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 13" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ATP-grasp" evidence="15">
        <location>
            <begin position="133"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="15">
        <location>
            <begin position="679"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="domain" description="MGS-like" evidence="16">
        <location>
            <begin position="943"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carboxyphosphate synthetic domain" evidence="13">
        <location>
            <begin position="1"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Allosteric domain" evidence="13">
        <location>
            <begin position="943"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
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        <location>
            <position position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
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        <location>
            <position position="830"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="847"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="849"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>4</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001777"/>
        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004812"/>
        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00009799"/>
        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
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        <source>
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        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ALN57587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="QCW26167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="1081" mass="117405" checksum="518854187E0B84B5" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGV3</accession>
    <name>A0A0S2DGV3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aldo/keto reductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Aryl-alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_12580</name>
        <name evidence="3" type="ORF">GLE_2503</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW26373.1"/>
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        <property type="protein sequence ID" value="ALN57852"/>
        <property type="gene ID" value="GLE_2503"/>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="InterPro"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
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        <property type="entry name" value="SSF51430"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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            <begin position="15"/>
            <end position="287"/>
        </location>
    </feature>
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            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="309" mass="33471" checksum="EF45A29C6C6F7CD4" modified="2016-02-17" version="1">MRYSFLGSTGLKVSELCLGATEFGGSTPADEARRIWARCLDAGVNFVDTADFSPESERLLGEWIGDRRDQLVISSKVFRRTGPGPNQLGLSRKHIVQSCEASLRRLKTDYIDLYFAHSDDFLTPLEETLGAFDQLVRQGKVLYLGASNYAAWRLNEALWTAQGNGWARYCCVQALYNLHQRDIEAELLPMCAHKGLGAIAWSPLARGALTDAKAGREAAPAAVDAALAQVAAQLGRPRAQVALRWALNRAGMNAVAMGPSSLAQAEENLGACDLELDAGQMAALDAAGAPRRPYPANLEPLARALRNDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGZ9</accession>
    <name>A0A0S2DGZ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hemolysin activation/secretion protein family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2328</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2328"/>
    <dbReference type="EnsemblBacteria" id="ALN57677">
        <property type="protein sequence ID" value="ALN57677"/>
        <property type="gene ID" value="GLE_2328"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2328"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2292"/>
    <dbReference type="OMA" id="TYFTAPQ"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005565">
        <property type="entry name" value="Hemolysn_activator_HlyB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013686">
        <property type="entry name" value="Polypept-transport_assoc_ShlB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08479">
        <property type="entry name" value="POTRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03865">
        <property type="entry name" value="ShlB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POTRA_2" evidence="2">
        <location>
            <begin position="8"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="ShlB" evidence="1">
        <location>
            <begin position="148"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="501" mass="54212" checksum="6580300285A898CA" modified="2016-02-17" version="1">MPAAAARFDILAYQVLGNSKLSNLDIEKVVYPHLGPKRSEEDVENARAALQSLYDSRGYPTVSVAIPEQDVATGLVTLQVNEQKIGRLRVNGADYFSPDDIERAAPSLAEGAVPNFKDVQRDIVALNQLPDRRVTPEIKAGTTPNTVDVDLNVEDKLPLHGSLELNNRNSANTSDQRLAASVRYDNLWQLGHSISLSAQVAPQRSSDAQVYSASYLARFGASPWSLLGYAVRSKSDIAVVGDLNVIGNGTLAGLRLMRSFAAGEGFYHSLSVGADYKDFTESLIQGADRGAVPIEYFPLSVNYNADWVKERSVAELALSAVFNLRGVGDGRAAFDAKRYQAQPNFFYLRAGGSYTWKSAGDAQLMLRLQTQFAGEPLISNEQFSIGGLDSVRGYYESEALGDLGGAATLEARTPSFADKLGDAFQELRLRAFVDAGYARINDPLPEQSRSETLVSAGLGATIKAFGHLNGSIDVAHPLSSPSGRERKPDSVEVGVRLWGEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH33</accession>
    <name>A0A0S2DH33_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Methyltransferase domain family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_2642</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947700.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57990">
        <property type="protein sequence ID" value="ALN57990"/>
        <property type="gene ID" value="GLE_2642"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2642"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2601"/>
    <dbReference type="OrthoDB" id="1515497at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000179">
        <property type="term" value="F:rRNA (adenine-N6,N6-)-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="rADc" evidence="5">
        <location>
            <begin position="96"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="291" mass="32190" checksum="1513988653393983" modified="2016-02-17" version="1">MQDFRSQRPAPASFADPAAGDAGEAPCAGEIWRSRADPAEAVMVLRCGADAVDYAWLDRDAADGRTPLAHWAQRFEVVLEQADHTHATPVRRHWLIDTQAERLRGARVLELGAHTGGLTQALLVHAAQVVAVENNPRCVRHLRERFGERLGIVAGDMHHALWDLGQDRFDVVVCAGVLYHSAHPFLLLEAMAHLRPRAILIDTLDDGVAELRVAVPNLVNSCNYRYNRRPDCGYSMVLGERLIAGAMARLGYGAMQRIDTAAATIAPERDSAYFQQWRRSLSAWFLRDGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHE4</accession>
    <name>A0A0S2DHE4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Oxoglutarate dehydrogenase (succinyl-transferring)</fullName>
            <ecNumber evidence="4">1.2.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">sucA</name>
        <name evidence="9" type="ORF">BV903_19815</name>
        <name evidence="10" type="ORF">FE772_13630</name>
        <name evidence="8" type="ORF">GLE_2723</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the alpha-ketoglutarate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.2" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000058">
        <property type="protein sequence ID" value="OPD62181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947766.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000058.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2723"/>
    <dbReference type="EnsemblBacteria" id="ALN58071">
        <property type="protein sequence ID" value="ALN58071"/>
        <property type="gene ID" value="GLE_2723"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62181">
        <property type="protein sequence ID" value="OPD62181"/>
        <property type="gene ID" value="BV903_19815"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2723"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2681"/>
    <dbReference type="OMA" id="RDSYCRT"/>
    <dbReference type="OrthoDB" id="29166at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004591">
        <property type="term" value="F:oxoglutarate dehydrogenase (succinyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032106">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011603">
        <property type="entry name" value="2oxoglutarate_DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031717">
        <property type="entry name" value="KGD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042179">
        <property type="entry name" value="KGD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152">
        <property type="entry name" value="PTHR23152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16078">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16870">
        <property type="entry name" value="OxoGdeHyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000157">
        <property type="entry name" value="Oxoglu_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00239">
        <property type="entry name" value="2oxo_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Transket_pyr" evidence="7">
        <location>
            <begin position="594"/>
            <end position="787"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD62181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW26547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="943" mass="103687" checksum="ED8BA8DD3A647BC0" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHI4</accession>
    <name>A0A0S2DHI4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YcII domain protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">YciI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_06075</name>
        <name evidence="5" type="ORF">FE772_13915</name>
        <name evidence="3" type="ORF">GLE_2787</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YciI family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000011">
        <property type="protein sequence ID" value="OPD64776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947812.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000011.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2787"/>
    <dbReference type="EnsemblBacteria" id="ALN58135">
        <property type="protein sequence ID" value="ALN58135"/>
        <property type="gene ID" value="GLE_2787"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64776">
        <property type="protein sequence ID" value="OPD64776"/>
        <property type="gene ID" value="BV903_06075"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2787"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2743"/>
    <dbReference type="OMA" id="MWYMISS"/>
    <dbReference type="OrthoDB" id="1780176at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII" evidence="2">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD64776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="99" mass="10798" checksum="23B1CD145C847879" modified="2016-02-17" version="1">MWYLIEGYDVADALPKRGPARPAHLQRLHDLRDQGRLLLAGPCPAIDAEDPGPAGFSGSVIVAEFESLDAARAWADADPYVEAGVYARVDVRPFRKVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHJ3</accession>
    <name>A0A0S2DHJ3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Copper resistance protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">copB</name>
        <name evidence="4" type="ORF">FE772_13180</name>
        <name evidence="3" type="ORF">GLE_2629</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2629"/>
    <dbReference type="EnsemblBacteria" id="ALN57977">
        <property type="protein sequence ID" value="ALN57977"/>
        <property type="gene ID" value="GLE_2629"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2629"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2588"/>
    <dbReference type="OMA" id="DMSDMDH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006878">
        <property type="term" value="P:cellular copper ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036709">
        <property type="entry name" value="Autotransporte_beta_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007939">
        <property type="entry name" value="Cu-R_B_prcur"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05275">
        <property type="entry name" value="CopB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103515">
        <property type="entry name" value="SSF103515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033243132" evidence="2">
        <location>
            <begin position="25"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="372" mass="40825" checksum="40AA640327FC7BB1" modified="2016-02-17" version="1">MKTTARLPRSALALALSFAGVAGAQQHDHAAHATDAAPAAAMDRSRMNHSHAGNKTPAKTAAAQSKAAAADPAQTNHSQMDHSRMDHSGPATPAAASEPDAAMDRSKMDHSQMDHSKMDHSQMGHGAAPRADAPQQPREPIPAVTDADRTAAFPPISLHMQHAPEFGHMVVFNRLEAVDAEHGSAQAWEGQAWFGNDTDRLWLRSEGEREDGRTESANLEALYGRAISPWWDVVAGVRHDFRPERSQTWAAFGLQGLSPYKFEVSATAYLGERGQSALNLEAEYELLLTNRLILQPLVEVEFYGKDDPRRETGAGLSSAEAGLRLRYEFSRKFAPYIGVSWERAFGDTADYRRAHGERIEDTRLVAGVRLWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHM6</accession>
    <name>A0A0S2DHM6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58009">
        <property type="protein sequence ID" value="ALN58009"/>
        <property type="gene ID" value="GLE_2661"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2661"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2620"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046116">
        <property type="entry name" value="DUF6053"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19523">
        <property type="entry name" value="DUF6053"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="84" mass="8321" checksum="307E09359060D1E2" modified="2016-02-17" version="1">MGGALAPTLFAQVASGFHRGGSESVGPEGPPTEAKALPQEHRLEAYVGGASAPTPFAQVASGFHRDGSESVGPEGPPTAAKALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHP7</accession>
    <name>A0A0S2DHP7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chain length determinant protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_12280</name>
        <name evidence="3" type="ORF">GLE_2458</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947552.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2458"/>
    <dbReference type="EnsemblBacteria" id="ALN57807">
        <property type="protein sequence ID" value="ALN57807"/>
        <property type="gene ID" value="GLE_2458"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2458"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2420"/>
    <dbReference type="OMA" id="DRELDNS"/>
    <dbReference type="OrthoDB" id="727511at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="448"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="199"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="369"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="499" mass="55133" checksum="B7BDF8E599E8730D" modified="2016-02-17" version="1">MDLDLDRDPAARPAPSAAPSAASALREWLEIAFRDKRRIAAAFALCFGLTVLAALLPTARYQSEASVLVRLGHEYVYVADNTDGSSGGAMPLMFDRTEALSAETQILASRDLIAEVVRHVGLGRLYPDIARQREDSDRPKLDQAVERFRQGLDAQLLKGATVIQIGFSHRDPALAQAALRTLLQTYLARRAAVFSDGQVRFLEGQVAAVDKRLQRAEQDLSRFKRAHGIVDYGQQIGLLLQQGNELESRLNDTDQQARTASERAKTLTRLANATPANLVQFSESLGDPQVPRQLLELRLKEQGLRSRYVDDNPLVVNAGNDVATAEAFIRDQRKAPPTTVRTGRNPVREAAELDLLRARSDESALAGSRKALQDTLQQLRRRADELSRQQIELAALSREQKLLEDSYGNYARKLEAARITEAREQKQRTTVSVLQAASWPLKAKSARLPILAIGLCLSVVAALLVAFLSQALRSSFQSPEQLERAFGLPVLATLPRVQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHX7</accession>
    <name>A0A0S2DHX7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLE_2765</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2765"/>
    <dbReference type="EnsemblBacteria" id="ALN58113">
        <property type="protein sequence ID" value="ALN58113"/>
        <property type="gene ID" value="GLE_2765"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2765"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2722"/>
    <dbReference type="OMA" id="DWWSIGN"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595606" evidence="6">
        <location>
            <begin position="32"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="67"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="7">
        <location>
            <begin position="407"/>
            <end position="802"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
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            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN58113.1"/>
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</entry>
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">YC36</strain>
        </source>
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            <end position="234"/>
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    </feature>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="ALN58343.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW26756.1"/>
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    </evidence>
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            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
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            <dbReference type="Proteomes" id="UP000308311"/>
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    </evidence>
    <sequence length="662" mass="73363" checksum="C0D461373DCFA842" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI51</accession>
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            <dbReference type="Pfam" id="PF04471"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI74</accession>
    <name>A0A0S2DI74_LYSEN</name>
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        </submittedName>
    </protein>
    <gene>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Fernandez C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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    </dbReference>
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        <source>
            <dbReference type="Pfam" id="PF03135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58163.1"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="817" mass="91341" checksum="746CDF850553EEFA" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIA7</accession>
    <name>A0A0S2DIA7_LYSEN</name>
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        <submittedName>
            <fullName evidence="4">DUF2721 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_06555</name>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
    <dbReference type="EMBL" id="MTAY01000011">
        <property type="protein sequence ID" value="OPD64850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947880.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000011.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2880"/>
    <dbReference type="EnsemblBacteria" id="ALN58228">
        <property type="protein sequence ID" value="ALN58228"/>
        <property type="gene ID" value="GLE_2880"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64850">
        <property type="protein sequence ID" value="OPD64850"/>
        <property type="gene ID" value="BV903_06555"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2880"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2842"/>
    <dbReference type="OMA" id="IYESRHN"/>
    <dbReference type="OrthoDB" id="1812267at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021279">
        <property type="entry name" value="DUF2721"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11026">
        <property type="entry name" value="DUF2721"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="161" mass="17531" checksum="8B0AC59D946E8256" modified="2016-02-17" version="1">MTANAPDVHYAILTAMLAPAFFLTATASLLLSANNRLARVIDRARVLLKELAETEDAEERELIERHILRQKKRSRIILRGSQLLYTAISFFVGTSLTVAGDAVLGYRLGLVPTVLAAFGVLSMFAASLLLARESSLAVEAVNEEMDHGHASAVKRWAKARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIF9</accession>
    <name>A0A0S2DIF9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2063 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2968</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947947.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2968"/>
    <dbReference type="EnsemblBacteria" id="ALN58316">
        <property type="protein sequence ID" value="ALN58316"/>
        <property type="gene ID" value="GLE_2968"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2968"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2929"/>
    <dbReference type="OMA" id="WQLELAH"/>
    <dbReference type="OrthoDB" id="1675974at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018640">
        <property type="entry name" value="DUF2063"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044922">
        <property type="entry name" value="DUF2063_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09836">
        <property type="entry name" value="DUF2063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2063" evidence="1">
        <location>
            <begin position="8"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="261" mass="28963" checksum="0F6C775CFFA99BD0" modified="2016-02-17" version="1">MSERLRRQQFALTRHLRDPNRYPPPPGIEERRLRVYRELLFGSIEGLLAGGFPVVRATLGEADWRALVRRFYAAHRCATPLFPLVGGEFVDFLQRPRGRVRGAPWLAELAHYEWAEAALLSCDDAAPAHRADGDLLDGVPLLAPWAWPLAYRWPVHEIGPALRPRRAPAAPTLLLVHRDRDGDVRFARLTPLSYRLLAAVRAQPRSGADHLRALAVEAGAPAESWFAEGRAALAQWRDQGVVLGTAAEAVPPSSAIARSRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DII9</accession>
    <name>A0A0S2DII9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58348">
        <property type="protein sequence ID" value="ALN58348"/>
        <property type="gene ID" value="GLE_3000"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3000"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2961"/>
    <dbReference type="OMA" id="ARIAQWT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="141" mass="14987" checksum="0D4A9EBE4CDD15CB" modified="2016-02-17" version="1">MGKRNKQAAAKPAASPTTTLRHLWLAGLGLAAVARREALAGAGRAAGQVEALQRRVREAASDARGNVVDGIENVRGQVEPKVVQFSAEVEARLAPVLDKLGLKGQRKPRAQRKGRKPAAKSKAPAARRAPRKPAARRARKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIJ0</accession>
    <name>A0A0S2DIJ0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Flavocytochrome MsrQ</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">msrQ</name>
        <name evidence="11" type="ORF">FE772_14935</name>
        <name evidence="10" type="ORF">GLE_2986</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="8">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="8">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the MsrQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2986"/>
    <dbReference type="EnsemblBacteria" id="ALN58334">
        <property type="protein sequence ID" value="ALN58334"/>
        <property type="gene ID" value="GLE_2986"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2986"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2947"/>
    <dbReference type="OMA" id="LHFFWMR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01207">
        <property type="entry name" value="MsrQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022837">
        <property type="entry name" value="MsrQ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36964">
        <property type="entry name" value="PTHR36964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0288">FMN</keyword>
    <keyword evidence="8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Ferric oxidoreductase" evidence="9">
        <location>
            <begin position="72"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN58334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW26748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="227" mass="25279" checksum="846B31389059BF62" modified="2016-02-17" version="1">MSDAVPAAAAAPVARRAASPRKTPPGVVAAKALAHLLALTPAAILGWQVWQEFSTGQGGLGADPVAEIEHRLGLWALRFLMIALAVTPLRQLSGQAVLLRFRRLLGLYAFFYASLHFAAYLVLDLRGYWTQVFEEIAKRPYITVGFLAWLGLVPLAITSTQGMMRRLGRLWGRLHQLVYAIAVLAVLHFWWLVKSDIREPALYAGILAALLGWRVWKRLNKRRPKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIN4</accession>
    <name>A0A0S2DIN4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3004</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58352">
        <property type="protein sequence ID" value="ALN58352"/>
        <property type="gene ID" value="GLE_3004"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3004"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2965"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="43" mass="4540" checksum="50F4AFD4BD6D711F" modified="2016-02-17" version="1">MQGLYGRGRIAVLLGLTAVVGGASAPMLSFPVVRGDRIEKRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIX2</accession>
    <name>A0A0S2DIX2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-dependent RNA helicase DeaD</fullName>
            <ecNumber evidence="6">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Cold-shock DEAD box protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 13" type="primary">deaD</name>
        <name evidence="6" type="synonym">csdA</name>
        <name evidence="13" type="ORF">GLE_3131</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948065.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3131"/>
    <dbReference type="EnsemblBacteria" id="ALN58478">
        <property type="protein sequence ID" value="ALN58478"/>
        <property type="gene ID" value="GLE_3131"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3131"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3089"/>
    <dbReference type="OMA" id="LPQGMPK"/>
    <dbReference type="OrthoDB" id="626183at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070417">
        <property type="term" value="P:cellular response to cold"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12499">
        <property type="entry name" value="RRM_EcCsdA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00964">
        <property type="entry name" value="DEAD_helicase_DeaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034415">
        <property type="entry name" value="CsdA_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005580">
        <property type="entry name" value="DbpA/CsdA_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028618">
        <property type="entry name" value="DEAD_helicase_DeaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03880">
        <property type="entry name" value="DbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="12">
        <location>
            <begin position="13"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="44"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="239"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="440"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="628"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="7">
        <location>
            <begin position="13"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="452"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="536"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="655"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN58478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="678" mass="74471" checksum="C32B50328B9815B8" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIZ0</accession>
    <name>A0A0S2DIZ0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3136</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3136"/>
    <dbReference type="EnsemblBacteria" id="ALN58483">
        <property type="protein sequence ID" value="ALN58483"/>
        <property type="gene ID" value="GLE_3136"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3136"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3094"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="HI0933-like_dom_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TIGR00275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="394" mass="42553" checksum="39E1F961443CDE02" modified="2016-02-17" version="1">MAERFDALVVGAGAAGLMCALTAGRRGRRVLVIEHANKVGKKILMSGGGRCNFTNTGTTPANYLSANPHFCKSALARYTPWDFIAMVERHRIAYHEKELGQLFCDVSSKLIVKMLVDECLAAGVRIETDCSIERIAHEDGGDFRAHTARGAFAAPALAVASGGLSIPSMGASGFGYEIARRFGHDVLPTRAGLVPLTLSGKHQERLADLSGLSLPVTASCNGRDFSNQMLITHRGVSGPSILQISSYWQPGDDLRLDLLPGRDALEWLQRQQRERAAAELKTVLGETLPKRFAQRLCEHWLANKPLKQYNLPELKQLAATLSAWPLVASGTEGYRTAEVTLGGVDTDGVSSSTMQSKRVPGLYFIGEVLDVTGWLGGYNFQWAWASGNAAGLAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ07</accession>
    <name>A0A0S2DJ07_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF1684 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_15730</name>
        <name evidence="1" type="ORF">GLE_3164</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3164"/>
    <dbReference type="EnsemblBacteria" id="ALN58510">
        <property type="protein sequence ID" value="ALN58510"/>
        <property type="gene ID" value="GLE_3164"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3164"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3120"/>
    <dbReference type="OMA" id="NLPCAYT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012467">
        <property type="entry name" value="DUF1684"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41913">
        <property type="entry name" value="PTHR41913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07920">
        <property type="entry name" value="DUF1684"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="340" mass="36510" checksum="93656C6A66361D6E" modified="2016-02-17" version="1">MTAAVRSCAVPAAGALPSHSGASRWWLCAAAALALAGCGSPEQQARAEREAERAVHAIQDFQRDQQIWREQRHRELLKPDGWTSLVGLHPIEPGAHYFGSDADNGIRVGVGPGHIGLLNLDKGRLRFVPERGLALTLNEQPLKGAAVLLADDSPAGPTRIGFDEGKGVLTAIKRGGRWYLRVRHADAPSRVGFSAIEYWPAKQDWKLSAKFVAHPAGQTIEVANIIGVIEPTPNPGAVEFERDGRSFRLEALDQGGEELMLVFADRTSGHGSYSAGRFLDVPRPNPQGKVTVDFNKAYNPPCAFTPFATCPLPPQGNRLDLEVTAGEKAYKPAGAAAHAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ30</accession>
    <name>A0A0S2DJ30_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3208</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58554">
        <property type="protein sequence ID" value="ALN58554"/>
        <property type="gene ID" value="GLE_3208"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3208"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3163"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="44" mass="4167" checksum="A4C14C61BCFE546E" modified="2016-02-17" version="1">MDGAGAAGKGAVTTPAAVGASAIAMAASRLAPFLQSDLVPRLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ82</accession>
    <name>A0A0S2DJ82_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_17680</name>
        <name evidence="4" type="ORF">FE772_16605</name>
        <name evidence="2" type="ORF">GLE_3364</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000048">
        <property type="protein sequence ID" value="OPD62507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948240.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000048.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58710">
        <property type="protein sequence ID" value="ALN58710"/>
        <property type="gene ID" value="GLE_3364"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62507">
        <property type="protein sequence ID" value="OPD62507"/>
        <property type="gene ID" value="BV903_17680"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3364"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3314"/>
    <dbReference type="OrthoDB" id="2173109at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595105" evidence="1">
        <location>
            <begin position="26"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="77" mass="8432" checksum="5ABC43C39A012DC1" modified="2016-02-17" version="1">MNVLSKTLCALGLCGLLLSMPAARADPVEGSFYTETTCEYAGWAFEIVLTKYRYTGGQWTVVSRTTTYAESCPPLEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ88</accession>
    <name>A0A0S2DJ88_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycine cleavage system transcriptional repressor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">gvcR</name>
        <name evidence="2" type="ORF">GLE_3184</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3184"/>
    <dbReference type="EnsemblBacteria" id="ALN58530">
        <property type="protein sequence ID" value="ALN58530"/>
        <property type="gene ID" value="GLE_3184"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3184"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3139"/>
    <dbReference type="OMA" id="TGGTMLN"/>
    <dbReference type="OrthoDB" id="1859752at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016867">
        <property type="entry name" value="GcvR"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028103">
        <property type="entry name" value="GcvR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR028103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="186" mass="20588" checksum="C526AC1D9268DA41" modified="2016-02-17" version="1">MTDSASRPSPNDNHLLINAYTTHPESPLLSVTRRIADSGCNLVDARLATVGRDVSVTALAQGSWDSVAKLEAMMARLEREEGLKLVWYRTGAKQVQSNLLPYIVEVVAADKPGILFQLADFFDRQGITIESLHCSRYRAMQTGADMFSAQITIGVPSSMHIAALRDDFLEFCDHLNLDAIMDPMKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ99</accession>
    <name>A0A0S2DJ99_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ECF sigma factor family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Sigma-70 family RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_15630</name>
        <name evidence="2" type="ORF">GLE_3142</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948074.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000027.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3142"/>
    <dbReference type="EnsemblBacteria" id="ALN58489">
        <property type="protein sequence ID" value="ALN58489"/>
        <property type="gene ID" value="GLE_3142"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3142"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3100"/>
    <dbReference type="OMA" id="RWESRTH"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011517">
        <property type="entry name" value="RNA_pol_sigma70_ECF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07638">
        <property type="entry name" value="Sigma70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02999">
        <property type="entry name" value="Sig-70_X6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="221" mass="25040" checksum="912D65B7C03E3FA7" modified="2016-02-17" version="1">MTQESPPPDSTAAPAGPDAFEFPQATLDSVTQLIAAAQGGQPGAWDRVYALLYNDLHEAASLQIRRRWRRGSKRSPTSLINRTWLRLNQDKLTLNNRQHLLAVLSQAMRYALLDEVRRLKRLKYEESYLADKADPHYEPSYDPDLDQLLSIDRALEALSAVEPRLTQLVEMRYFAGMSDIEIGEVLGLTDRTIRRDWRKARAFLAAHLRVGPDLDGEDDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJN4</accession>
    <name>A0A0S2DJN4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA(Ile)-lysidine synthase</fullName>
            <ecNumber evidence="7">6.3.4.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">tRNA(Ile)-2-lysyl-cytidine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">tRNA(Ile)-lysidine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">tilS</name>
        <name evidence="9" type="ORF">GLE_3394</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + cytidine(34) in tRNA(Ile2) + L-lysine = AMP + diphosphate + H(+) + lysidine(34) in tRNA(Ile2)</text>
            <dbReference type="Rhea" id="RHEA:43744"/>
            <dbReference type="Rhea" id="RHEA-COMP:10625"/>
            <dbReference type="Rhea" id="RHEA-COMP:10670"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:83665"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.19"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the tRNA(Ile)-lysidine synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.19" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948263.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3394"/>
    <dbReference type="EnsemblBacteria" id="ALN58740">
        <property type="protein sequence ID" value="ALN58740"/>
        <property type="gene ID" value="GLE_3394"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3394"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3343"/>
    <dbReference type="OMA" id="WHGDHQW"/>
    <dbReference type="OrthoDB" id="666797at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01992">
        <property type="entry name" value="PP-ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01161">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012796">
        <property type="entry name" value="Lysidine-tRNA-synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012094">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012795">
        <property type="entry name" value="tRNA_Ile_lys_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015262">
        <property type="entry name" value="tRNA_Ile_lys_synt_subst-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033">
        <property type="entry name" value="PTHR43033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09179">
        <property type="entry name" value="TilS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11734">
        <property type="entry name" value="TilS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00977">
        <property type="entry name" value="TilS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02433">
        <property type="entry name" value="lysidine_TilS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02432">
        <property type="entry name" value="lysidine_TilS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TilS_C" evidence="8">
        <location>
            <begin position="357"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="26"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN58740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="433" mass="46743" checksum="269F24E86DAF3718" modified="2016-02-17" version="1">MPASGADALPAALAALPAAPLCVGYSGGLDSSALLHALAASPQARARGLRAWHVHHGLHPQADAWAAHCADVCAGYGLELTVSRVSVARDGGDGPEAAARAARHAAFAAGLGAGEVLALAHHRDDQAETVLLRLLRGSGPDGLAAMREWRECGRGRLWRPLLALSRAQLEAYAQHHGLRWIDDPSNAEDRYDRNFLRQRVLPLLRERWPQAPAALAQSARLQEDAAGLLEEGDALALAQARSLDPHALSRSALRALAPARRARVLRRWIAALGLPPLPAQGVARIDTELLSARADADAEFAWNGARVRAWRDLLHAAPQRPPLPPDWRADWDGAAPLALPGGGRWHLHGTDRFDAVLRAHPRAGGERIALPGRDHRHSLKHALQALGVPPWERERLPLLSAADGELLAAGDLLYSARLQAWLRERAARLEWEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJQ2</accession>
    <name>A0A0S2DJQ2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3477</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58822">
        <property type="protein sequence ID" value="ALN58822"/>
        <property type="gene ID" value="GLE_3477"/>
    </dbReference>
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    <dbReference type="PATRIC" id="fig|69.6.peg.3424"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="118" mass="13224" checksum="CEED2D795617E19F" modified="2016-02-17" version="1">MRAREFFARRAPLRGTRESGRTRPGRPRARAQPTEAAAMRDRRRRSASRAMAAAVAAQADARVRCEMRSPAIVANAGFSAFTRPRPHRAARRLGFGGRAFRPDAFVSGRRNLKQKHRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJR8</accession>
    <name>A0A0S2DJR8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3493</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58838">
        <property type="protein sequence ID" value="ALN58838"/>
        <property type="gene ID" value="GLE_3493"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3493"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3438"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="59" mass="6126" checksum="B31BAD932E12A90E" modified="2016-02-17" version="1">MAATARERCAAHDPNATAVAVSRGPRLQCALWPRHARAADPPTDSTPARRAGHAAARAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK01</accession>
    <name>A0A0S2DK01_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_16725</name>
        <name evidence="1" type="ORF">GLE_3391</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948260.1">
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58737">
        <property type="protein sequence ID" value="ALN58737"/>
        <property type="gene ID" value="GLE_3391"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3391"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3340"/>
    <dbReference type="OrthoDB" id="922874at1224"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="261" mass="28399" checksum="84DECC0CDCF9F81C" modified="2016-02-17" version="1">MALGTFFKWAGGGAVALLAALCLLLQGAYWYGASMLPEQLPQPRREYPALARETLWRSLGGGDSAISVRRLNIFSYAGLIFEAVATYLARPGELAKEPADLRLVDWTSSAVRSAIVEARYAHIVAPSPSPSGGSNAEALQQLSYDHQFESLALFIRSSREWPAERMADLVLDSGDYGRDSATLEQAALAYFAQPVERLTREELTVLVLLDRGLGDRDPHCHAQAFREAYADALQTIGDPKLPALSAQTLVRLQPIACPPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK88</accession>
    <name>A0A0S2DK88_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_18310</name>
        <name evidence="1" type="ORF">GLE_3717</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948497.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59061">
        <property type="protein sequence ID" value="ALN59061"/>
        <property type="gene ID" value="GLE_3717"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3717"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3662"/>
    <dbReference type="OrthoDB" id="1961380at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="96" mass="10546" checksum="CEBE1B6BC5C7E74E" modified="2016-02-17" version="1">MRDDTQPITAEVLDPVVNCAIVKLSSRAFPGVLLQGDTLYTMYCRAQHALAGLDPATDEDEYDTLADLVEHLGECLGIYERTLARCGYSLPYYTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKG6</accession>
    <name>A0A0S2DKG6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_18230</name>
        <name evidence="1" type="ORF">GLE_3700</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948483.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59044">
        <property type="protein sequence ID" value="ALN59044"/>
        <property type="gene ID" value="GLE_3700"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3700"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3644"/>
    <dbReference type="OrthoDB" id="1784317at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="148" mass="16470" checksum="423EAD51FAEAB9D4" modified="2016-02-17" version="1">MHRLPLDRNDFIPLPAAVPLGPGLSQRAGQTAAGDGVAQAAHSIDELRASVYPMAPEVIDMESELGYWRGHYRGLPGGSALRYGDYEPAVKLGMDAYMRSRGRGIDDMEDELEACYRRTRGLSRLDWQQARAVVRLAWNHLHLRGLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL01</accession>
    <name>A0A0S2DL01_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Magnesium transport protein CorA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 8" type="primary">corA</name>
        <name evidence="9" type="ORF">FE772_17865</name>
        <name evidence="8" type="ORF">GLE_3631</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Mediates influx of magnesium ions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948429.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58975">
        <property type="protein sequence ID" value="ALN58975"/>
        <property type="gene ID" value="GLE_3631"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3631"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3575"/>
    <dbReference type="OMA" id="IQKYFRD"/>
    <dbReference type="OrthoDB" id="822653at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015087">
        <property type="term" value="F:cobalt ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004488">
        <property type="entry name" value="Mg/Co-transport_prot_CorA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="SSF143865"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="SSF144083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00383">
        <property type="entry name" value="corA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW27219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="330" mass="37310" checksum="71FA5FA49754FCDB" modified="2016-02-17" version="1">MSDPSLPQCVINCAAYDRNGGRRDITLDQISDVLAVDDGSFVWVGLYEPDENILDKLQEEFCLHDLAVEDAHNAHQRPKIEAYGNSLFIAIHTAQKIDNRIRFGETHLFVGPRYLVTVRHGASISYKNARMRMEREPDLLEHGPGAALYAVLDSVVDNFMPIVEGFTQELNELEKDIFAEDFRNETVRELYDLKRELTRLRMAVSPLQDILGQLARSRGGLIDEEIQLYFRDVLDHAVRINETTDTLREMLTAAVSVNLSLVTVRQGEIVKRLGAWAALLAAPTLIASWYGMNFTHMPELAGQFSYGILISVVVVTCLVLYIGFKRAKWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL42</accession>
    <name>A0A0S2DL42_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 5">Thymidylate synthase</fullName>
            <shortName evidence="5">TS</shortName>
            <shortName evidence="5">TSase</shortName>
            <ecNumber evidence="1 5">2.1.1.45</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">thyA</name>
        <name evidence="8" type="ORF">GLE_3920</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + dUMP = 7,8-dihydrofolate + dTMP</text>
            <dbReference type="Rhea" id="RHEA:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57451"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="2.1.1.45"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Pyrimidine metabolism; dTTP biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.45" evidence="1 5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3920"/>
    <dbReference type="EnsemblBacteria" id="ALN59262">
        <property type="protein sequence ID" value="ALN59262"/>
        <property type="gene ID" value="GLE_3920"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3920"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3857"/>
    <dbReference type="OMA" id="KQYLDLC"/>
    <dbReference type="UniPathway" id="UPA00575"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004799">
        <property type="term" value="F:thymidylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006231">
        <property type="term" value="P:dTMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00351">
        <property type="entry name" value="TS_Pyrimidine_HMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.572.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00008">
        <property type="entry name" value="Thymidy_synth_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045097">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023451">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036926">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000398">
        <property type="entry name" value="Thymidylate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020940">
        <property type="entry name" value="Thymidylate_synthase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11548">
        <property type="entry name" value="PTHR11548"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00303">
        <property type="entry name" value="Thymidylat_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00108">
        <property type="entry name" value="THYMDSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55831">
        <property type="entry name" value="SSF55831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03284">
        <property type="entry name" value="thym_sym"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00091">
        <property type="entry name" value="THYMIDYLATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4 5" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylat_synt" evidence="7">
        <location>
            <begin position="3"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="89"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="129"/>
            <end position="132"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="170"/>
            <end position="172"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="227" mass="25372" checksum="99B773BB42B9CEAD" modified="2016-02-17" version="1">MNAGFPLVTTKKLHLRSIVHELLWFLQGATNIAYLKDNKVSIWDEWADADGELGPVYGKQWRSWSDGAGGEIDQIRWVVEEIKRNPDSRRLMVSAWNVADLPKMALMPCHALFQFYVVDGKLSCQLYQRSGDIFLGVPFNIASYALLTHMVAQVCGLGVGDFVHTLGDAHLYSNHFEQAREQLARAPRALPRLKLDPTVTDLFAFGYDDIAIEGYDPAPAIKAPVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL44</accession>
    <name>A0A0S2DL44_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MazG family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3943</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3943"/>
    <dbReference type="EnsemblBacteria" id="ALN59285">
        <property type="protein sequence ID" value="ALN59285"/>
        <property type="gene ID" value="GLE_3943"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3943"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3880"/>
    <dbReference type="OMA" id="HPHIYGD"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004518">
        <property type="entry name" value="MazG_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011551">
        <property type="entry name" value="NTP_PyrPHydrolase_MazG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30522">
        <property type="entry name" value="PTHR30522"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03819">
        <property type="entry name" value="MazG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00444">
        <property type="entry name" value="mazG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MazG" evidence="1">
        <location>
            <begin position="31"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="MazG" evidence="1">
        <location>
            <begin position="171"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="275" mass="30550" checksum="DF9C107DE5F39A0B" modified="2016-02-17" version="1">MLNLPPGIAGLLEIMARLRDPQRGCPWDVEQTFATIVPYTIEEAYEVADAVDRGDRDALKDELGDLLLQVVFHARMAQEEGAFGFDDVVAAISDKMVRRHPHVFGEASVEDAQAQTAAWEELKRREREAAGEADASALAGIARGLPEWQRAVKLQKRAATVGFDWPAPTPVIAKLHEEIEEVRAEFDAVAAAPDDAAARDRLEEEIGDVLFVCANLARHAKVDVGAALRRANLKFERRFRAMELQAAQDGMALAELPLERQDDYWEQAKRAERGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL55</accession>
    <name>A0A0S2DL55_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59039">
        <property type="protein sequence ID" value="ALN59039"/>
        <property type="gene ID" value="GLE_3695"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3695"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3639"/>
    <dbReference type="OMA" id="LWRCSNP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="115" mass="12479" checksum="82F074B6A9226661" modified="2016-02-17" version="1">MLTTPDGRYIVVRGRLWRATSPHLSATQKAQAVGDLMAARRAVAAAAGRADALREARRRVDQAKRALGERGPVWWTDGAPDYNRRMIQRSPYAAWYAATSAGEAEGDAPGGDGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLA5</accession>
    <name>A0A0S2DLA5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3984</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59326">
        <property type="protein sequence ID" value="ALN59326"/>
        <property type="gene ID" value="GLE_3984"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3984"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="72" mass="7221" checksum="4433575EDDFF8D90" modified="2016-02-17" version="1">MAEDAVEDFECGGRHGPSLAARPRAAVGECAGRGVGRRRGGGSGAAGGSCGRALRPDALFSGRGDRSGRHRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLD3</accession>
    <name>A0A0S2DLD3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rplD</name>
        <name evidence="8" type="ORF">BV903_23030</name>
        <name evidence="9" type="ORF">FE772_18645</name>
        <name evidence="7" type="ORF">GLE_3789</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Forms part of the polypeptide exit tunnel.</text>
    </comment>
    <comment type="function">
        <text evidence="5">One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000077">
        <property type="protein sequence ID" value="OPD61616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948554.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000077.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3789"/>
    <dbReference type="EnsemblBacteria" id="ALN59133">
        <property type="protein sequence ID" value="ALN59133"/>
        <property type="gene ID" value="GLE_3789"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61616">
        <property type="protein sequence ID" value="OPD61616"/>
        <property type="gene ID" value="BV903_23030"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3789"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3733"/>
    <dbReference type="OMA" id="PQVHILE"/>
    <dbReference type="OrthoDB" id="1572673at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01328_B">
        <property type="entry name" value="Ribosomal_L4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_L4/L1e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_L4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013005">
        <property type="entry name" value="Ribosomal_uL4/L1e"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746">
        <property type="entry name" value="PTHR10746"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="SSF52166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03953">
        <property type="entry name" value="rplD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="42"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD61616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW27360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="201" mass="21810" checksum="76330F7485F5F453" modified="2016-02-17" version="1">MELAINNSSKTLSVSDEIFGREFSEDLVHQVVVAYRNAGRAGTKAQKTRSEVNGTTKKSKKQKGGGARHGALTAPIFVGGGVTFAAKPRSFAQKVNRKMYRAAIAAILSELNRQGRITVVESFDIDAPKTKGLIEKLKSLEVGRRPLIVTEEATENLYLSARNLPYVEVRDVQGLDPVALVGADSVVLTSDAVKKIEEWLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLJ0</accession>
    <name>A0A0S2DLJ0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4006</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59348">
        <property type="protein sequence ID" value="ALN59348"/>
        <property type="gene ID" value="GLE_4006"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4006"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3943"/>
    <dbReference type="OMA" id="RQEFARM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007251">
        <property type="entry name" value="Iron_permease_Fet4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04120">
        <property type="entry name" value="Iron_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="74" mass="8593" checksum="984D6797BDC153D4" modified="2016-02-17" version="1">MINTATTIVTFLMVFLIQNTQSRDTEAIQIKLDELIRATEQANNALMDIEELDEESLDAFRRRYEELAARSRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLJ2</accession>
    <name>A0A0S2DLJ2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3963</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59305">
        <property type="protein sequence ID" value="ALN59305"/>
        <property type="gene ID" value="GLE_3963"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3963"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3900"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="47" mass="5229" checksum="902227FCCA735806" modified="2016-02-17" version="1">MRSRLYFKPHAGCQARIPRPETEYASRSDRRTNLPAVTLSPAAAPST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLN0</accession>
    <name>A0A0S2DLN0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase, GNAT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4011</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4011"/>
    <dbReference type="EnsemblBacteria" id="ALN59353">
        <property type="protein sequence ID" value="ALN59353"/>
        <property type="gene ID" value="GLE_4011"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4011"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3948"/>
    <dbReference type="OMA" id="FHRHTDT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="109" mass="11457" checksum="BC17235FF0CFF7CD" modified="2016-02-17" version="1">MAELDGALLGVVAVQACGDIGLLRSLTVDANGRGRGLGQALVERAEAHARARGLLRLVLLTETAAAFFSRRGYVPAERGDMPAQIQSTAQFRSLCPATASCWSKHLGPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLQ1</accession>
    <name>A0A0S2DLQ1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Type II secretion system protein E</fullName>
            <shortName evidence="3">T2SS protein E</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Type II traffic warden ATPase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">gspE</name>
        <name evidence="5" type="ORF">GLE_4183</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4183"/>
    <dbReference type="EnsemblBacteria" id="ALN59525">
        <property type="protein sequence ID" value="ALN59525"/>
        <property type="gene ID" value="GLE_4183"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4183"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4125"/>
    <dbReference type="OMA" id="QAGMRTM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037257">
        <property type="entry name" value="T2SS_E_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013369">
        <property type="entry name" value="T2SS_GspE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007831">
        <property type="entry name" value="T2SS_GspE_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05157">
        <property type="entry name" value="T2SSE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160246">
        <property type="entry name" value="SSF160246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02533">
        <property type="entry name" value="type_II_gspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="T2SP_E" evidence="4">
        <location>
            <begin position="404"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="588" mass="64225" checksum="3689EF024D690CBE" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLZ7</accession>
    <name>A0A0S2DLZ7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Subtilase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_3849</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948595.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3849"/>
    <dbReference type="EnsemblBacteria" id="ALN59192">
        <property type="protein sequence ID" value="ALN59192"/>
        <property type="gene ID" value="GLE_3849"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3849"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3789"/>
    <dbReference type="OMA" id="WQFSRGA"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595421" evidence="6">
        <location>
            <begin position="29"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="7">
        <location>
            <begin position="159"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="463" mass="45536" checksum="FB3F34D0AA7EE83F" modified="2016-02-17" version="1">MPASSHRLNALAAATALALLGAAAPACAGQAHLAGLGDDGNRQYIVKFRGGSAPSREVAAMKAALDAAAARAGAPKLSALRAMALPGMRVVTTPGPLKRAQATALMRQLAADPNVEFVQVDGGVTVKMTPNDPQFSRQWHYADTAAGIRAPTAWNATAGAGVVVAVVDSGILSHTDLNANVLPGYDFVSAVNGRNAAECAIDGLSAGCGKSLDGDGRDANPHDAGNIPHGNHVAGTIAAVTNNGLGVAGIAHAAKIVPVRAAGSQGYNAHSDTIDAIVWASGGHVAGVPDNLNPAEVINVSLGSDIACTPAWQAGVDAAAANGALVVVAAGNGNNDVSGNVPAGCNNVVAVAATDKNGAKSSFSAWGAKIDLAAPGGDGLFNQVQSTVANNGYGAMSGTSMASPHVAGVAALVRSLAPGKTPAQVEALLKSTARPIPASKCSRGCGAGLVDAAAAVAAAQSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMC3</accession>
    <name>A0A0S2DMC3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TIGR02678 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_20950</name>
        <name evidence="2" type="ORF">GLE_4279</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948927.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4279"/>
    <dbReference type="EnsemblBacteria" id="ALN59620">
        <property type="protein sequence ID" value="ALN59620"/>
        <property type="gene ID" value="GLE_4279"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4279"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4218"/>
    <dbReference type="OMA" id="GYERRRY"/>
    <dbReference type="OrthoDB" id="1197197at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013494">
        <property type="entry name" value="CHP02678"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09661">
        <property type="entry name" value="DUF2398"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02678">
        <property type="entry name" value="TIGR02678"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="422" mass="46903" checksum="AFE09FC26734F8AE" modified="2016-02-17" version="1">MSPRPPHRRSRSVGEWQQTQQQDEFRRALRALLMWPLMASAHPEFSAVRRQAERLREWFAREAGWPLQVDREGARLYKRPANVSDPSRGLPGYDRRRYVLLCLACAVLERADPQITLRLIGERVVQQAGDHALAEQGFAFTLGTPGERRELVAVCRTLLDHGVLERVAGEEENFVREGVGQQADALYDVHRRLLAGLLAAVRGPSTWSAEDAPIGLEARLHALLAGFEVDSEQGRRDAMRHRLTRRLLDDPVLYLDSLDEETYGYFVNQRGVLAARLCDATGLVAEQRAEGLALVDESGQLTDVAMPAEGTEAHVTLLVAEYLATRLRRARVPIHVAEAEIASFLREAAARYGKFWRKSARAPGAERELTDIAVERLCRLGLLTRVDGAVLPLPAIARFALGRTEVRDAAGTASLLPLAADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMR5</accession>
    <name>A0A0S2DMR5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative peptidoglycan binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4488</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949094.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4488"/>
    <dbReference type="EnsemblBacteria" id="ALN59829">
        <property type="protein sequence ID" value="ALN59829"/>
        <property type="gene ID" value="GLE_4488"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4488"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4425"/>
    <dbReference type="OrthoDB" id="1803009at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PG_binding_1" evidence="2">
        <location>
            <begin position="187"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="2">
        <location>
            <begin position="519"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="575"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="740"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="575"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="760" mass="80216" checksum="780FCAC362D4D668" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN43</accession>
    <name>A0A0S2DN43_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Efflux ABC transporter, permease protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="11">FtsX-like permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FE772_21785</name>
        <name evidence="10" type="ORF">GLE_4464</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949074.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4464"/>
    <dbReference type="EnsemblBacteria" id="ALN59805">
        <property type="protein sequence ID" value="ALN59805"/>
        <property type="gene ID" value="GLE_4464"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4464"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4401"/>
    <dbReference type="OMA" id="NWFGGVY"/>
    <dbReference type="OrthoDB" id="768211at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="306"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="352"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="9">
        <location>
            <begin position="23"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="291"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW27885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="388" mass="42189" checksum="1AFA00FD0070BC10" modified="2016-02-17" version="1">MKYFHLIWAELMRRKTRTALTLLSIVAAFLLFGLLDGVRESFDQAGNSANGAKRLQTGSRLSFIQPLPMSLNDRIAQVQGVKQVSYANWFGGAYQDPHNQIFSFAVASNYLDLYPEIQVDKAQRKAFDETRTGVLVGAQLMQRFGWKVGQKLPLQSTIFPNSDGSKNWNFDIVGTIAAADKKTGGWYDQMVLLHWKYFDDSNPYNRGQVGWYITEVGDVNQADRVAKAIDAISANSDHESKTQTEAASAANWMKQMADIGLIVGSIMGAVFFTLVLLTGNTMAQAVRERTSELAVLKTIGFPDRSVLMLVLAESVLLLLIGGVVGVALARLMGPIVSAGSRGAINIPPISGHSWALALGLMVAIGLVVGALPAIRAMRLNIVDALAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN47</accession>
    <name>A0A0S2DN47_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endoribonuclease L-PSP family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_21350</name>
        <name evidence="2" type="ORF">GLE_4370</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948998.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4370"/>
    <dbReference type="EnsemblBacteria" id="ALN59711">
        <property type="protein sequence ID" value="ALN59711"/>
        <property type="gene ID" value="GLE_4370"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4370"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4309"/>
    <dbReference type="OMA" id="YGDTKTQ"/>
    <dbReference type="OrthoDB" id="1850770at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="165" mass="17196" checksum="2DC552693CF45AD3" modified="2016-02-17" version="1">MSGAGETVRRHRFDGGDGHGQGPQAGDRLLASGGALPFLAAATLPPGCELVLLSGHTPPVIDAAVPADRIAAYGDTFAQTDGTLGELQRSLHGLGLTMGDLVQLRVYVVGDPALGGRMDNEGFSRAYSRWFGTPEQPRLVARTRVQVAGLVNPGWLVEIEAVAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNA6</accession>
    <name>A0A0S2DNA6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">NADP-dependent malic enzyme</fullName>
            <ecNumber evidence="11">1.1.1.40</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">maeB</name>
        <name evidence="12" type="ORF">FE772_23245</name>
        <name evidence="11" type="ORF">GLE_4777</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the malic enzymes family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.40" evidence="11"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949308.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4777"/>
    <dbReference type="EnsemblBacteria" id="ALN60118">
        <property type="protein sequence ID" value="ALN60118"/>
        <property type="gene ID" value="GLE_4777"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4777"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4711"/>
    <dbReference type="OMA" id="NIWVTDL"/>
    <dbReference type="OrthoDB" id="654531at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004471">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004473">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008948">
        <property type="term" value="F:oxaloacetate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05311">
        <property type="entry name" value="NAD_bind_2_malic_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045213">
        <property type="entry name" value="Malic_NAD-bd_bact_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012188">
        <property type="entry name" value="ME_PTA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042113">
        <property type="entry name" value="P_AcTrfase_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042112">
        <property type="entry name" value="P_AcTrfase_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002505">
        <property type="entry name" value="PTA_PTB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01515">
        <property type="entry name" value="PTA_PTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036684">
        <property type="entry name" value="ME_PTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="4 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="malic" evidence="10">
        <location>
            <begin position="19"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Malic_M" evidence="9">
        <location>
            <begin position="164"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="77"/>
            <end position="84"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR036684-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR036684-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR036684-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN60118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW28131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="770" mass="83682" checksum="762F36DB50CA4A56" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNC7</accession>
    <name>A0A0S2DNC7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Calmodulin-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_23025</name>
        <name evidence="2" type="ORF">GLE_4737</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949274.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4737"/>
    <dbReference type="EnsemblBacteria" id="ALN60078">
        <property type="protein sequence ID" value="ALN60078"/>
        <property type="gene ID" value="GLE_4737"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4737"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4671"/>
    <dbReference type="OrthoDB" id="1499496at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044159">
        <property type="entry name" value="IQM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31250">
        <property type="entry name" value="PTHR31250"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="158" mass="17826" checksum="CBBCB9A58346B6D0" modified="2016-02-17" version="1">MSDKYLTTPRRPQFEGEHLPGNRVWHGTHVHYLSDAELPGYRVRIRDGLLYGADGALFDTRDAYTHWSGRGRAIFVMHGDGALYSAPEHRVGEFHHSSLGQGQPVAGAGELEAREGRLLAITDHSSHYCPPRRFTEQVLAELAEGGVDLRWVTQEFRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNM7</accession>
    <name>A0A0S2DNM7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4815</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60156">
        <property type="protein sequence ID" value="ALN60156"/>
        <property type="gene ID" value="GLE_4815"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4815"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4746"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="39" mass="4672" checksum="E6F8E8AD3C80358B" modified="2016-02-17" version="1">MRSLRGAALHAIARTRFFDDRKSRAFPMRRLRDCVMHKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNV8</accession>
    <name>A0A0S2DNV8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF1203 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_23685</name>
        <name evidence="1" type="ORF">GLE_4877</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949382.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60218">
        <property type="protein sequence ID" value="ALN60218"/>
        <property type="gene ID" value="GLE_4877"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4877"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4808"/>
    <dbReference type="OMA" id="RSARNNC"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009593">
        <property type="entry name" value="DUF1203"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06718">
        <property type="entry name" value="DUF1203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF034110">
        <property type="entry name" value="DUF1203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="160" mass="17639" checksum="AB2BAB9835301D51" modified="2016-02-17" version="1">MHAYRIDGLAPHAFAPLFALDDDALRAHGMRRVVADSPTGYPCRVSLAEAAPGERLLLLTFEHHDCDGPYRASGPIFVREGAARAPTLRNRLPSILATRHLSLRAYDGDGWMLQARALEGRDAEAAVQELFEDPRVARIHAHNARYGCFLCTIAREPAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP93</accession>
    <name>A0A0S2DP93_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription termination factor Rho</fullName>
            <ecNumber evidence="8">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">ATP-dependent helicase Rho</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">rho</name>
        <name evidence="13" type="ORF">BV903_06750</name>
        <name evidence="12" type="ORF">GLE_4918</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">C3</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">B25</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homohexamer. The homohexamer assembles into an open ring structure.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the Rho family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000012">
        <property type="protein sequence ID" value="OPD64726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4918"/>
    <dbReference type="EnsemblBacteria" id="ALN60259">
        <property type="protein sequence ID" value="ALN60259"/>
        <property type="gene ID" value="GLE_4918"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64726">
        <property type="protein sequence ID" value="OPD64726"/>
        <property type="gene ID" value="BV903_06750"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4918"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4848"/>
    <dbReference type="OMA" id="TRLCRAH"/>
    <dbReference type="OrthoDB" id="1619125at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008186">
        <property type="term" value="F:ATP-dependent activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04459">
        <property type="entry name" value="Rho_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01128">
        <property type="entry name" value="rho_factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01884">
        <property type="entry name" value="Rho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041703">
        <property type="entry name" value="Rho_factor_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011112">
        <property type="entry name" value="Rho_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036269">
        <property type="entry name" value="Rho_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011113">
        <property type="entry name" value="Rho_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004665">
        <property type="entry name" value="Term_rho"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46425">
        <property type="entry name" value="PTHR46425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07498">
        <property type="entry name" value="Rho_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07497">
        <property type="entry name" value="Rho_RNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00959">
        <property type="entry name" value="Rho_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68912">
        <property type="entry name" value="SSF68912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00767">
        <property type="entry name" value="rho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51856">
        <property type="entry name" value="RHO_RNA_BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 8" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="Rho RNA-BD" evidence="11">
        <location>
            <begin position="227"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="93"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="348"/>
            <end position="353"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="360"/>
            <end position="365"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="391"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN60259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OPD64726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="597" mass="65135" checksum="577717A1AD72A1E0" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPG2</accession>
    <name>A0A0S2DPG2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tetratricopeptide repeat domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_15975</name>
        <name evidence="1" type="ORF">GLE_4715</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000041">
        <property type="protein sequence ID" value="OPD62967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949258.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60056">
        <property type="protein sequence ID" value="ALN60056"/>
        <property type="gene ID" value="GLE_4715"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62967">
        <property type="protein sequence ID" value="OPD62967"/>
        <property type="gene ID" value="BV903_15975"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4715"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4649"/>
    <dbReference type="OrthoDB" id="1896869at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD62967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="178" mass="18968" checksum="0A076DEBFA473BDF" modified="2016-02-17" version="1">MTEPRPDLTALLQRAHAAIAQARDVEAVRLLQRVLECDPDNVHAQYLLAIQHAQLGLYDRAEQRLRAVLARLPGFVVARFQLAQLLLMRGIASDARQWLRPVLDAPAPLGDYARALDAAAAGEAARACALIEAAQRLPQPIPELAADMDRLLAGLRAAPANAAGGTSAPTPPARVAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPS8</accession>
    <name>A0A0S2DPS8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Metal/formaldehyde-sensitive transcriptional repressor</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_10555</name>
        <name evidence="5" type="ORF">D9T17_05255</name>
        <name evidence="4" type="ORF">FE772_23525</name>
        <name evidence="2" type="ORF">GLE_4843</name>
    </gene>
    <organism evidence="2 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">C3</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 9" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FrmR/RcnR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000023">
        <property type="protein sequence ID" value="OPD64020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000015">
        <property type="protein sequence ID" value="ROU08198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949354.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4843"/>
    <dbReference type="EnsemblBacteria" id="ALN60184">
        <property type="protein sequence ID" value="ALN60184"/>
        <property type="gene ID" value="GLE_4843"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64020">
        <property type="protein sequence ID" value="OPD64020"/>
        <property type="gene ID" value="BV903_10555"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4843"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4773"/>
    <dbReference type="OMA" id="DCGPILQ"/>
    <dbReference type="OrthoDB" id="1868412at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003735">
        <property type="entry name" value="Metal_Tscrpt_repr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038390">
        <property type="entry name" value="Metal_Tscrpt_repr_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33677">
        <property type="entry name" value="PTHR33677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02583">
        <property type="entry name" value="Trns_repr_metal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU08198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="90" mass="9716" checksum="CFD87E24B8E6CD90" modified="2016-02-17" version="1">MPHSPAEKKLVLARVRRIKGQAEALERALEAGSECAAVLQQIAAIRGAVNGLMSQVLESHIREELGQAVADRGREASIDEIAALVRSYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPU1</accession>
    <name>A0A0S2DPU1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FE772_24665</name>
        <name evidence="9" type="ORF">GLE_5088</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949547.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5088"/>
    <dbReference type="EnsemblBacteria" id="ALN60429">
        <property type="protein sequence ID" value="ALN60429"/>
        <property type="gene ID" value="GLE_5088"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5088"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5015"/>
    <dbReference type="OMA" id="DVTNCIG"/>
    <dbReference type="OrthoDB" id="71288at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726693" evidence="6">
        <location>
            <begin position="35"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="60"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="7">
        <location>
            <begin position="393"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN60429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW28366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="930" mass="98783" checksum="2150717A8C3F8BCE" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPU6</accession>
    <name>A0A0S2DPU6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Tetracycline resistance protein, class A (TetA(A))</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLE_5172</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60513">
        <property type="protein sequence ID" value="ALN60513"/>
        <property type="gene ID" value="GLE_5172"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5172"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5094"/>
    <dbReference type="OMA" id="LYADSFH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="192"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="399"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="432"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="9">
        <location>
            <begin position="65"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN60513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="475" mass="48232" checksum="C7CD79E04FBA5B48" modified="2016-02-17" version="1">MRTPIQSPAAAPAEPAGSASPAGPMPAEPTPAPAAGRDPPGAEATATTRSPAPAPAPGASGLNLALVLILATVALDAIGIGLIAPVLPQLLDAFGVHANLALHAGALTALYALMQFVCAPALGALSDRFGRRPVLLCSLFGSALDYLLMACAPWLSLLYLGRAIAGVSGASGSVAGAYIADISDESQRARRYGWLGASFGLGLVAGPVIGGLLGAVWLRAPFLAAAALATLNFALAWLALPEPRRPRAPAPQRARPSLRELAPWHSLRELGRLPDLAPLLWLYLAMQLAGQVPGTLWAIYGHDRFGWNPTAVGLSLAAFGIIHSLFQAFATGRISDRFGPSRTLLGGVISDVLGYLAFAFARSVATLAPGLLLAAGGGIGGPALLAMSSERTDEARQGALQGVLASLASLAAVIGPLLFGAIYVAGAGHWDGWVWVVGAALYLPCVPALRKLLRGPANASAAPADAAPIEAAPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPW1</accession>
    <name>A0A0S2DPW1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">LacI family DNA-binding transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">LacI family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BV903_07940</name>
        <name evidence="8" type="ORF">FE772_25130</name>
        <name evidence="6" type="ORF">GLE_5188</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">C3</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000016">
        <property type="protein sequence ID" value="OPD64468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949619.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5188"/>
    <dbReference type="EnsemblBacteria" id="ALN60529">
        <property type="protein sequence ID" value="ALN60529"/>
        <property type="gene ID" value="GLE_5188"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64468">
        <property type="protein sequence ID" value="OPD64468"/>
        <property type="gene ID" value="BV903_07940"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5188"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5108"/>
    <dbReference type="OMA" id="YVLNGPA"/>
    <dbReference type="OrthoDB" id="664909at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
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        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
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        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HTHLACI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="5">
        <location>
            <begin position="4"/>
            <end position="58"/>
        </location>
    </feature>
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            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN60529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD64468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW28447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="348" mass="37803" checksum="D1DC3C2F77EBC559" modified="2016-02-17" version="1">MRRPTIKDVAELAQVSLKTVSRVINDESGVRARTRARVHEAIAELDYRPDPSARSLRSAQPYALGVVYDNPNPYYIISVQNGVLAACRETGYGLQIHPCDSSSPLLAADLIDLVQGARLAGLVLAPPMSERMELVSELLAHGIKLVRIVSAAEDPRDGAPCVWVDDRDAAYDITEHLIQLGHQRIGFLWGGKSHRSSWERYKGYAQALTDYGIGEDENLVLPGDYSFDDGFRGARRLFALPDRPTAIFGSNDEIAAGVLAAAKSSGMHVPYDLSIAGFEDSPFSKQSWPTLTTARQATEEIARHAAYRLIAELRRESDTPAEAPANEGFSPILVVRGSTAPPRPAGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPX1</accession>
    <name>A0A0S2DPX1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tetratricopeptide repeat domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_06640</name>
        <name evidence="1" type="ORF">GLE_4891</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000012">
        <property type="protein sequence ID" value="OPD64709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60232">
        <property type="protein sequence ID" value="ALN60232"/>
        <property type="gene ID" value="GLE_4891"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64709">
        <property type="protein sequence ID" value="OPD64709"/>
        <property type="gene ID" value="BV903_06640"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4891"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4822"/>
    <dbReference type="OrthoDB" id="2018331at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD64709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="146" mass="15649" checksum="110123BC3C0EC9EC" modified="2016-02-17" version="1">MDMNALPDDLESRVLDLANQAIAHQAAGEHRQAAKHWGRAIALADSGLGSDDIRHWLSAGAAETLYRLGDYAACIVAARAAQEWSRQQHAPLAALLLGQAQLRLGRREAALQALREARALGGEAVWDAIDLDLRAAAARLLRSDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ58</accession>
    <name>A0A0S2DQ58_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">EamA family transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Integral membrane protein DUF6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_05075</name>
        <name evidence="3" type="ORF">GLE_5370</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000009">
        <property type="protein sequence ID" value="OPD65108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949755.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000009.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60711">
        <property type="protein sequence ID" value="ALN60711"/>
        <property type="gene ID" value="GLE_5370"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65108">
        <property type="protein sequence ID" value="OPD65108"/>
        <property type="gene ID" value="BV903_05075"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5370"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5285"/>
    <dbReference type="OMA" id="MVMMAIE"/>
    <dbReference type="OrthoDB" id="1515911at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQU5</accession>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="47" mass="4828" checksum="9AED646B188E8249" modified="2016-02-17" version="1">MGGASAPTPFDPMRHTAQDRRPATSASPPPRRADLPALAAIAAHTPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DRE7</accession>
    <name>A0A0S2DRE7_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_00930</name>
        <name evidence="2" type="ORF">GLE_5538</name>
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        <name type="scientific">Lysobacter enzymogenes</name>
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            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60879">
        <property type="protein sequence ID" value="ALN60879"/>
        <property type="gene ID" value="GLE_5538"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5538"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5457"/>
    <dbReference type="OMA" id="REANICR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="9"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="116" mass="12659" checksum="7C742E42D137E977" modified="2016-02-17" version="1">MLTSFGKTLRKIRIDHAITLGQLGALTGVSAAFISALERGKPVPANFIAKVCQELALKPEEVLELERAAAHQTKEITLTINGRSDKARELAVAFARRFESLSDDEVQKILGSLSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-11-13" modified="2020-06-17" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A8BB78</accession>
    <name>A8BB78_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HSAF sterol desaturase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Sterol desaturase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_3213</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2007" name="Antimicrob. Agents Chemother." volume="51" first="64" last="72">
            <title>Structure and biosynthesis of heat-stable antifungal factor (HSAF), a broad-spectrum antimycotic with a novel mode of action.</title>
            <authorList>
                <person name="Yu F."/>
                <person name="Zaleta-Rivera K."/>
                <person name="Zhu X."/>
                <person name="Huffman J."/>
                <person name="Millet J.C."/>
                <person name="Harris S.D."/>
                <person name="Yuen G."/>
                <person name="Li X.C."/>
                <person name="Du L."/>
            </authorList>
            <dbReference type="PubMed" id="17074795"/>
            <dbReference type="DOI" id="10.1128/AAC.00931-06"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">C3</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2009-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Du L."/>
                <person name="Xie Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">C3</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="EF028635">
        <property type="protein sequence ID" value="ABL86392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58559">
        <property type="protein sequence ID" value="ALN58559"/>
        <property type="gene ID" value="GLE_3213"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3213"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3168"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="217"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="3">
        <location>
            <begin position="157"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABL86392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="353" mass="37982" checksum="9F9E9FE68E17EE5F" modified="2007-11-13" version="1">MNGLSEHTLETRAASQQESDATGQDGAAAAGAAIIAGPNADPVTPAATTRLDFLRHCAHPLLMLAVAGYAYAAIARGWDLGGANFAFVLLTVGYLALLERLIPYERRWLPDRREWGLYGVYFFLTVVGGALAQIPLMAAVSAVAPLHPALPLWAEIPLALLLSSLASYAVHRAGHDVPLLWRLHGVHHVPDKVNVGNNGVNHVLDVTLAQFVVQFSLALSGFSAHALFAVGIFVIAQGYFVHANIDVRLGWLNHVLASPELHRMHHSADKHEAGHFGSDLSVWDRLFGSYTWRPGKRPRQIGLFAPGTFPPNRALLSTLLHPLRPRRYPPVPPPSPACAPLASAAPAADRAPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA69</accession>
    <name>A0A0S2DA69_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phage-tail_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_01120</name>
        <name evidence="2" type="ORF">GLE_0037</name>
    </gene>
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        <lineage>
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    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="gene ID" value="GLE_0037"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0037"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.44"/>
    <dbReference type="OMA" id="VTWAHRD"/>
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    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032876">
        <property type="entry name" value="J_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13550">
        <property type="entry name" value="Phage-tail_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage-tail_3" evidence="1">
        <location>
            <begin position="201"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="737" mass="79001" checksum="D482BE882ACAE256" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAA4</accession>
    <name>A0A0S2DAA4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0104</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0104"/>
    <dbReference type="EnsemblBacteria" id="ALN55463">
        <property type="protein sequence ID" value="ALN55463"/>
        <property type="gene ID" value="GLE_0104"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0104"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.108"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594849" evidence="2">
        <location>
            <begin position="31"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="445" mass="45785" checksum="8171977D6CC2B0C8" modified="2016-02-17" version="1">MSLVRRAGAAVLTTAVLLAAAGCGPDPAPAETVPTLPAQAVTQLVSDLRRNDLAGYARHAVPPELHQRLEQAWSQGRTVWPLTELPLDDRFASFIAALAEQDAERKLVATYRRQFAGADTELRSAAKTLGLFASQYVRSEPGYSETERDHHAQLIEALSGWAQTAPLGDSQRAREAIPQLVSAARATGLAGPDGFAKAGMDRSLRRLGPFAERLKQVLGQYGLGLDAALDSVDASLAEQTGDTARVRVRYQLAGQPVDAYVLVERIDGRWYLSDVLRHARAEAEATSKPAPSATMAQRLAALAKVQARAPSAVPAKPAAAPAPAVPAVPATVAGDQAGAAPGAVPGAATEELKPVGAAVPAATEVRPEGAGKAAGARPAERALPEGKPAEARPSAADGRTGAGAKPAAGEAKPAAAGKSFPAEAKPASRSAAKPAAATGEPPKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAI7</accession>
    <name>A0A0S2DAI7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_01795</name>
        <name evidence="2" type="ORF">GLE_0184</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945859.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0184"/>
    <dbReference type="EnsemblBacteria" id="ALN55543">
        <property type="protein sequence ID" value="ALN55543"/>
        <property type="gene ID" value="GLE_0184"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0184"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.186"/>
    <dbReference type="OMA" id="GEFFWVA"/>
    <dbReference type="OrthoDB" id="2059359at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="227" mass="24427" checksum="5E0E64C08E2B04A1" modified="2016-02-17" version="1">MGEFFSTILTLPTAFYTVLLGVVVGYWLLSALGLAGGEMIDGWIGGDGHGHGAHGFGDHTLVDGAHHPQHGIFDPLMRLGLGGIPITVVLTVIVLVGWVLTYYADVYLLRLVPGTPLRIAAGAAIIFVNFCISLPVAALALRPLRKLLRKMQPGPPRPILGQVATIRSPVNRVTGTASVEDGGAGLILQIRDEDPQRFKRGDRIVLIEYLEDQNAYRAVSEDEFRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAY6</accession>
    <name>A0A0S2DAY6_LYSEN</name>
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        <submittedName>
            <fullName evidence="8">Thiol:disulfide interchange protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Thiol:disulfide interchange protein DsbA/DsbL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FE772_02465</name>
        <name evidence="8" type="ORF">GLE_0332</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW24704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945959.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0332"/>
    <dbReference type="EnsemblBacteria" id="ALN55690">
        <property type="protein sequence ID" value="ALN55690"/>
        <property type="gene ID" value="GLE_0332"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0332"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.329"/>
    <dbReference type="OMA" id="AVEFFWY"/>
    <dbReference type="OrthoDB" id="1805428at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015036">
        <property type="term" value="F:disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd03019">
        <property type="entry name" value="DsbA_DsbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023205">
        <property type="entry name" value="DsbA/DsbL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13462">
        <property type="entry name" value="Thioredoxin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0574">Periplasm</keyword>
    <keyword evidence="4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726634" evidence="6">
        <location>
            <begin position="23"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="7">
        <location>
            <begin position="68"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="33"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN55690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW24704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="286" mass="29711" checksum="28BB43D0B1C6FFEF" modified="2016-02-17" version="1">MNSRIATLSRYPLLLGALIALAACGKTETPAETAAPAAPAATETAPAAAPAEGTPAAPAAGETAAPAQADPAIAPAATATPPAGPAPVAGTDYQEIPGGQPFDPAPGKIEVAEIFSYTCPHCAQFEPLLVEWRKKQTADVKFTPIAGPFGANPIPFEKAFYAAQTLGLIDKTHEAMFRAVHIDQSIDYRTVNDQTFGDFYAKYGVKPADFIGTMNSFAITAKGKRAEQFMARSGVDASPSLVINGKYLVKGKGFEDYLRIADHLVARERAAMAGAAPAPAAAPVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB16</accession>
    <name>A0A0S2DB16_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Twin transmembrane helix small protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_23715</name>
        <name evidence="4" type="ORF">FE772_02280</name>
        <name evidence="2" type="ORF">GLE_0291</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000085">
        <property type="protein sequence ID" value="OPD61432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945931.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000085.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0291"/>
    <dbReference type="EnsemblBacteria" id="ALN55649">
        <property type="protein sequence ID" value="ALN55649"/>
        <property type="gene ID" value="GLE_0291"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61432">
        <property type="protein sequence ID" value="OPD61432"/>
        <property type="gene ID" value="BV903_23715"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0291"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.290"/>
    <dbReference type="OMA" id="RSLMFRV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021313">
        <property type="entry name" value="DUF2909"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11137">
        <property type="entry name" value="DUF2909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="75" mass="8163" checksum="9365786AC5A97440" modified="2016-02-17" version="1">MSQELKVLLVVAFLAVILWNLGAGLYYMLVDKGQSKRTVNALTRRIVLSVALILIVAVSIWMGWITPHGVGSNPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB57</accession>
    <name>A0A0S2DB57_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0407</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55765">
        <property type="protein sequence ID" value="ALN55765"/>
        <property type="gene ID" value="GLE_0407"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0407"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.404"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594909" evidence="1">
        <location>
            <begin position="25"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="245" mass="27091" checksum="27931763747C6FC0" modified="2016-02-17" version="1">MTAARFKPAVLAILISAVSCGVHAQGSNAGVRLSCIAAEKDAEGEWIATRDLSVSDGTATATRDRYEWRSAKRLSFGPGMTLKWELDYDWPRDEAARKTVREDRVAAILHFRFDAQAIGKPLKKPERSWIHFYRSTDPEERFSVSTSSLTSIMFWDKFDNGDLSTRAIVPLDHLLAFGTGFDTLVWNIRTAPDQFGATQAPAKGVIPIASMRGKVSKIPKLRLMLDKKSANFGSECHAPIVMTSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB76</accession>
    <name>A0A0S2DB76_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA protecting protein DprA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">dprA</name>
        <name evidence="4" type="ORF">GLE_0353</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DprA/Smf family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0353"/>
    <dbReference type="EnsemblBacteria" id="ALN55711">
        <property type="protein sequence ID" value="ALN55711"/>
        <property type="gene ID" value="GLE_0353"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0353"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.350"/>
    <dbReference type="OMA" id="LALWFEL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009294">
        <property type="term" value="P:DNA-mediated transformation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003488">
        <property type="entry name" value="DprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041614">
        <property type="entry name" value="DprA_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43022">
        <property type="entry name" value="PTHR43022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02481">
        <property type="entry name" value="DNA_processg_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17782">
        <property type="entry name" value="DprA_WH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00732">
        <property type="entry name" value="dprA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DprA_WH" evidence="3">
        <location>
            <begin position="402"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN55711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="466" mass="47524" checksum="B1C0A6360C71C5DE" modified="2016-02-17" version="1">MPDADAPASYPNQNPNPDPRAQPRGGPRPPAAPAGEAPLDAALDAAPAAATRTAGARSDGPIRSEADALALLRLLAAGGSSAARRALLDACGGAAAALAAGPSAWSQAALSTAQVARLRAPTGEAFWREAGWTDDADRRLLDWLARPDRQLIAWTDPDYPALLRRAPNPPLALFVAGEPGLLWHPAVAVVGSRSPTPAGSGNAAGFARALARSGLAVTSGLAAGIDATAHRAALDAGGLTVAVLGTGPDLAYPRRHADLLARIAAEGAVASEYPPGTQARPAHFPARNRIVAGLSLGTLVVEAAERSGALITARLAAECGREVFAVPGSIHNPLARGCHRLIREGAGLVESAAEVAAALAPVAAELADGLRRRLGAPIDGGHAAVIQAGQDGSGPVSGDADPAPAQTDFADPDYQSLWNALGFDPTGMDELVHRTGLTTAELSSMLLVMELEGRVAAQHGRYFRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBL6</accession>
    <name>A0A0S2DBL6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0574</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55932">
        <property type="protein sequence ID" value="ALN55932"/>
        <property type="gene ID" value="GLE_0574"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0574"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.567"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="132" mass="14027" checksum="380AC2BE36115B72" modified="2016-02-17" version="1">MHVVHVGLRIAHPRRQALRERRPGERRAHARRTASARQVARRNARGERRGAGRGKAACAVPTSATGRSPDSRATRMRPAGAFPRVRAVADAGCNSPTVAGAVPEWDSRPHRLPVSPCALAGAGGRTPVARAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBQ9</accession>
    <name>A0A0S2DBQ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0596</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55954">
        <property type="protein sequence ID" value="ALN55954"/>
        <property type="gene ID" value="GLE_0596"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0596"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.588"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="63" mass="6437" checksum="DE105C237372DFF5" modified="2016-02-17" version="1">MGACLCDERSGAGSTSDPCDAADSTARFVAPRNVAGPAAISFLRGLPAVSCPASPRTRQWEIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBR1</accession>
    <name>A0A0S2DBR1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0594</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55952">
        <property type="protein sequence ID" value="ALN55952"/>
        <property type="gene ID" value="GLE_0594"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0594"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.586"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="50" mass="5230" checksum="C7B5020C4910044E" modified="2016-02-17" version="1">MAEGSCTRAGGACGARELLNLAFVVRDNTPIARSGPEMVICDPQVLNVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBX7</accession>
    <name>A0A0S2DBX7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0678</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0678"/>
    <dbReference type="EnsemblBacteria" id="ALN56036">
        <property type="protein sequence ID" value="ALN56036"/>
        <property type="gene ID" value="GLE_0678"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0678"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.666"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="295" mass="31829" checksum="4C04C82630E034D2" modified="2016-02-17" version="1">MERSPISTSPRRRAKTRSFVLAALVAAFGLGEAAATVVLPRFPSEADYLACPGGQAWRDGTRARIDRADLLRRSLSPPRDPALREAVLRLSAQALQRPYLDGSNPGVEAAAAAADAAAAAADAAAAAADAAADSMADGKGAQPGRAPPSPPAEVQAAVRRLGDILRRQPMPGIAEIGEDGVQALWGAIERDRGDAARQERLAEAFLDTQRRSPGIDPFTLRNAMERVDELRLADGRRQRYGTQFDYPERKVVQRPVESERAMDAYRAEFGMMPAALETCLRQRLENPYGFLPGFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC40</accession>
    <name>A0A0S2DC40_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small-conductance mechanosensitive channel</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BV903_22555</name>
        <name evidence="5" type="ORF">GLE_0738</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">B25</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homoheptamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell inner membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000075">
        <property type="protein sequence ID" value="OPD61679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0738"/>
    <dbReference type="EnsemblBacteria" id="ALN56096">
        <property type="protein sequence ID" value="ALN56096"/>
        <property type="gene ID" value="GLE_0738"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61679">
        <property type="protein sequence ID" value="OPD61679"/>
        <property type="gene ID" value="BV903_22555"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0738"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.726"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0407">Ion channel</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU369025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD61679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="199" mass="22468" checksum="3480838A3F6A6D77" modified="2016-02-17" version="1">MLAQATYIATKIGEAFAILAIAWLLTTLLRQLLRRMSTRYDLAPAFALGLRRGLSTVIYITALLMFLNRVGISGSVVWTTLTGFVAVGAVAFFAAWSVLSNIFCAFLILTTRPFRLYDYIEVLENGDKPGLKGRVVDINFVYTTLQETHANGDDTVLQVPNSQFFQRTTRRWRHEPEWSRVVREQKTAESAEWQDAGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC50</accession>
    <name>A0A0S2DC50_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56098">
        <property type="protein sequence ID" value="ALN56098"/>
        <property type="gene ID" value="GLE_0740"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0740"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.728"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="77" mass="8213" checksum="A2CA25A9407DCEA0" modified="2016-02-17" version="1">MPAGASRRRKIVRAWRPPRGLGQRRAARRNRGDATMPATTTAAATTAGARAPTGPRAGDDAARGAILNPPWCLRRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC86</accession>
    <name>A0A0S2DC86_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HTH type transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">XRE family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_19960</name>
        <name evidence="4" type="ORF">D9T17_23270</name>
        <name evidence="2" type="ORF">GLE_0779</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">OH11</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000059">
        <property type="protein sequence ID" value="OPD62160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000058">
        <property type="protein sequence ID" value="ROU04570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946293.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000058.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0779"/>
    <dbReference type="EnsemblBacteria" id="ALN56137">
        <property type="protein sequence ID" value="ALN56137"/>
        <property type="gene ID" value="GLE_0779"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62160">
        <property type="protein sequence ID" value="OPD62160"/>
        <property type="gene ID" value="BV903_19960"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0779"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.768"/>
    <dbReference type="OMA" id="QFEWLAT"/>
    <dbReference type="OrthoDB" id="1933795at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="7"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROU04570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <sequence length="136" mass="14537" checksum="EB49D571378DDFBB" modified="2016-02-17" version="1">MTPQQRIRLARRHAGLSQAALGTAVGVQRSAVGHWESAQGKFPSVTHLREVALATGVQFEWLATGRGRMNLSQDTAMDSVAAADALLVEDALELRLLAAFREAPARARVPLVEIAEQLAQSRTGRSRALGKARGGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC93</accession>
    <name>A0A0S2DC93_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chaperonin GroEL</fullName>
            <ecNumber evidence="6">5.6.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">60 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Chaperonin-60</fullName>
            <shortName evidence="6">Cpn60</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">groL</name>
        <name evidence="6" type="synonym">groEL</name>
        <name evidence="10" type="ORF">FE772_04615</name>
        <name evidence="9" type="ORF">GLE_0784</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <dbReference type="EC" id="5.6.1.7" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946297.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0784"/>
    <dbReference type="EnsemblBacteria" id="ALN56142">
        <property type="protein sequence ID" value="ALN56142"/>
        <property type="gene ID" value="GLE_0784"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0784"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.773"/>
    <dbReference type="OMA" id="LKDQHMN"/>
    <dbReference type="OrthoDB" id="265347at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00600">
        <property type="entry name" value="CH60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018370">
        <property type="entry name" value="Chaperonin_Cpn60_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="SSF48592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="SSF52029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="SSF54849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02348">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00296">
        <property type="entry name" value="CHAPERONINS_CPN60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="30"/>
            <end position="33"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="87"/>
            <end position="91"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="415"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="479"/>
            <end position="481"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="495"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW25062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="545" mass="57285" checksum="622F25EFC81C6A2B" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCV7</accession>
    <name>A0A0S2DCV7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0972</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56330">
        <property type="protein sequence ID" value="ALN56330"/>
        <property type="gene ID" value="GLE_0972"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0972"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.959"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="50" mass="5488" checksum="D9D0B9E9DF3A1ED1" modified="2016-02-17" version="1">MRSEQGRSGVPGCSSQDGEHAAYLVDQRFYFWQIGGSQPAYPLANQQLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCY9</accession>
    <name>A0A0S2DCY9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Probable alpha-L-glutamate ligase</fullName>
            <ecNumber evidence="7">6.3.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">rimK</name>
        <name evidence="11" type="ORF">FE772_05705</name>
        <name evidence="10" type="ORF">GLE_1022</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="7">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="7">Binds 2 magnesium or manganese ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the RimK family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.-" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946467.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1022"/>
    <dbReference type="EnsemblBacteria" id="ALN56380">
        <property type="protein sequence ID" value="ALN56380"/>
        <property type="gene ID" value="GLE_1022"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1022"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1010"/>
    <dbReference type="OMA" id="CYMNIAS"/>
    <dbReference type="OrthoDB" id="937913at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016881">
        <property type="term" value="F:acid-amino acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01552">
        <property type="entry name" value="RimK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013651">
        <property type="entry name" value="ATP-grasp_RimK-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023533">
        <property type="entry name" value="RimK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041107">
        <property type="entry name" value="Rimk_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004666">
        <property type="entry name" value="RpS6_RimK/Lys_biosynth_LsyX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08443">
        <property type="entry name" value="RimK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18030">
        <property type="entry name" value="Rimk_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00768">
        <property type="entry name" value="rimK_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 7" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="11" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="ATP-grasp" evidence="9">
        <location>
            <begin position="104"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="178"/>
            <end position="179"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="211"/>
            <end position="213"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN56380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW25227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="302" mass="32420" checksum="18514E3EEEAE6114" modified="2016-02-17" version="1">MKLAILSRNTKLYSTRRLVEAARDRGHSVRVLDPLRCYMRIASDGFQMHYKGREIAGYHAVIPRIGASVTRYGSAVLRQFELMDSYSPNSSDAILRARDKLRSHQLLAAQGIGLPATVFGDNPDDTADLLSMLGPPPHVIKLNEGTQGAGVMLTEKLSASKGVIEALRGLYANFLVQEFVAEAKGADLRCFVVGGKVVAAMKRQAPKGDFRSNLHRGGTAKGVRASAAEQDVAVRAAQVLGLGVAGVDLIRSARGPLVLEVNASPGLEGIEEASGVDVAIEIVDYVAGRVREKPARRLAARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD37</accession>
    <name>A0A0S2DD37_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adenosylhomocysteinase</fullName>
            <ecNumber evidence="4">3.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">S-adenosyl-L-homocysteine hydrolase</fullName>
            <shortName evidence="4">AdoHcyase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 9" type="primary">ahcY</name>
        <name evidence="10" type="ORF">FE772_05760</name>
        <name evidence="9" type="ORF">GLE_1033</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>H2O + S-adenosyl-L-homocysteine = adenosine + L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:21708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="3.3.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 6">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="4 6">Binds 1 NAD(+) per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 6">Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the adenosylhomocysteinase family.</text>
    </comment>
    <dbReference type="EC" id="3.3.1.1" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946477.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1033"/>
    <dbReference type="EnsemblBacteria" id="ALN56391">
        <property type="protein sequence ID" value="ALN56391"/>
        <property type="gene ID" value="GLE_1033"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1033"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1021"/>
    <dbReference type="OMA" id="NKYGCRE"/>
    <dbReference type="OrthoDB" id="522981at2"/>
    <dbReference type="UniPathway" id="UPA00314">
        <property type="reaction ID" value="UER00076"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004013">
        <property type="term" value="F:adenosylhomocysteinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00401">
        <property type="entry name" value="SAHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1480">
        <property type="match status" value="1"/>
    </dbReference>
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        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
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    </evidence>
    <sequence length="476" mass="51987" checksum="0EE9126565768BEC" modified="2016-02-17" version="1">MNAVPKTFSTEGDYKVADISLADWGRKEIDIAEHEMPGLMSIRKKYAAAQSLKGVRVTGSLHMTIQTAVLIETLRDLGADVRWASCNIFSTQDHAAAAIAASGTPVFAWKGESLEEYWDCTLAALSFPNGQGPELVVDDGGDVTLLIHKGYELENGDGWVNTPSGNHEEQVIKNLLKRVHAERPGFWHEVVKHWKGVSEETTTGVHRLYQLAEAGSLLVPAINVNDSVTKSKFDNLYGCRESLADGLKRAMDVMLAGKVAVVCGYGDVGKGSAHSLRAYGARVVVTEIDPINALQAAMEGFEVNTVESTLGRGDIYVTTTGNKDVLTLDHMSKMKDQAIVCNIGHFDNEIQVDALNASGAKRLNIKPQVDKYTFGNGNSIFLLAEGRLVNLGCATGHPSFVMSNSFSNQTLAQIDLWANKDTYEAKVYILPKKLDEEVARLHLEKIGVKLTTLTAEQAQYLGVSVDGPYKPDHYRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD61</accession>
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            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
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                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9 11">YC36</strain>
        </source>
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    <comment type="function">
        <text evidence="6">Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.</text>
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        </subcellularLocation>
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        <text evidence="2 6">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.</text>
    </comment>
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    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
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    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="9"/>
            <end position="278"/>
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        <location>
            <begin position="18"/>
            <end position="25"/>
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        <ligand>
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        <ligand>
            <name>GTP</name>
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        <location>
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            <end position="143"/>
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        <ligand>
            <name>GTP</name>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN56476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW25302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="534" mass="59128" checksum="1EAED24A97108C31" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDG2</accession>
    <name>A0A0S2DDG2_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="3" type="ORF">BV903_09850</name>
        <name evidence="2" type="ORF">GLE_1246</name>
    </gene>
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        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000021">
        <property type="protein sequence ID" value="OPD64170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_MTAY01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1246"/>
    <dbReference type="EnsemblBacteria" id="ALN56603">
        <property type="protein sequence ID" value="ALN56603"/>
        <property type="gene ID" value="GLE_1246"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64170">
        <property type="protein sequence ID" value="OPD64170"/>
        <property type="gene ID" value="BV903_09850"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1246"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1230"/>
    <dbReference type="OMA" id="EGTKWLK"/>
    <dbReference type="OrthoDB" id="2021063at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014469">
        <property type="entry name" value="DUF2271"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10029">
        <property type="entry name" value="DUF2271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF014995">
        <property type="entry name" value="UCP014995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595018" evidence="1">
        <location>
            <begin position="22"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="171" mass="18727" checksum="4D2E0DC30F5F6B13" modified="2016-02-17" version="1">MKPSMFKILIPALTLPLPAFAADLELNIEVPRINAAEYHRPYVAAWIEKADNSVASNLLVWYDVDMKNGEGTKWLKDMRQWWRRSGRTLSMPVDGVSGATRPVGQHAVAFKGGSKQLAGLAPGSYTLVVEAAREVGGREMLTIPFEWPAKAQKLSAQGKTELGKVGLVVKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDT5</accession>
    <name>A0A0S2DDT5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1335</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56692">
        <property type="protein sequence ID" value="ALN56692"/>
        <property type="gene ID" value="GLE_1335"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1335"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1317"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="92" mass="9769" checksum="AB404B3A6369A317" modified="2016-02-17" version="1">MHAAIVADPGAGRTVRRSGWVVADPRGRGVGVSGLRGGVEVIAAGRQSPPGPSRRLENRLLLLLLLLAWTSPHRRPLFRRPGGRAHGCARAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDU3</accession>
    <name>A0A0S2DDU3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1438</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56795">
        <property type="protein sequence ID" value="ALN56795"/>
        <property type="gene ID" value="GLE_1438"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1438"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1418"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="96" mass="10825" checksum="8BCDDFD9382F173D" modified="2016-02-17" version="1">MLTLTPKQERWMMLIVLALIAIAMYAAAWQSLFGPSGRKEDVEVWWIVAVSMAFTYQAGYRNVLKNLGPLVFVLALLLPTTLQLIGVAIRLVRIYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDY1</accession>
    <name>A0A0S2DDY1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DoxX family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_07420</name>
        <name evidence="7" type="ORF">GLE_1402</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DoxX family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946750.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1402"/>
    <dbReference type="EnsemblBacteria" id="ALN56759">
        <property type="protein sequence ID" value="ALN56759"/>
        <property type="gene ID" value="GLE_1402"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1402"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1383"/>
    <dbReference type="OMA" id="HGGYALE"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07681">
        <property type="entry name" value="DoxX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN56759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW25521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="131" mass="13511" checksum="269B1E4E563E7154" modified="2016-02-17" version="1">MTTERWSDLGKLILRLSLGALILLHGIAKLRGGTEGIVGMVEAHGLPGFLGYGVLLGEVLGPALLILGWHARIGAVLVAGNMLVAIALVHLGQLGQLNDQGGWAIELQAMFLATAAAVALLGPGKYSLNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDY4</accession>
    <name>A0A0S2DDY4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2-amino-3-ketobutyrate coenzyme A ligase</fullName>
            <shortName evidence="1">AKB ligase</shortName>
            <ecNumber evidence="1">2.3.1.29</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Glycine acetyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 3" type="primary">kbl</name>
        <name evidence="4" type="ORF">BV903_24485</name>
        <name evidence="5" type="ORF">FE772_07060</name>
        <name evidence="3" type="ORF">GLE_1318</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + glycine = (2S)-2-amino-3-oxobutanoate + CoA</text>
            <dbReference type="Rhea" id="RHEA:20736"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78948"/>
            <dbReference type="EC" id="2.3.1.29"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
        <text evidence="1">Binds 1 pyridoxal phosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-threonine degradation via oxydo-reductase pathway; glycine from L-threonine: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.29" evidence="1"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000095">
        <property type="protein sequence ID" value="OPD61280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946684.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000095.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1318"/>
    <dbReference type="EnsemblBacteria" id="ALN56675">
        <property type="protein sequence ID" value="ALN56675"/>
        <property type="gene ID" value="GLE_1318"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61280">
        <property type="protein sequence ID" value="OPD61280"/>
        <property type="gene ID" value="BV903_24485"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1318"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1302"/>
    <dbReference type="OMA" id="MDTHGFG"/>
    <dbReference type="OrthoDB" id="479874at2"/>
    <dbReference type="UniPathway" id="UPA00046">
        <property type="reaction ID" value="UER00506"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008890">
        <property type="term" value="F:glycine C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019518">
        <property type="term" value="P:L-threonine catabolic process to glycine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00985">
        <property type="entry name" value="2am3keto_CoA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011282">
        <property type="entry name" value="2am3keto_CoA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01822">
        <property type="entry name" value="2am3keto_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="41"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="1">
        <location>
            <begin position="109"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="1">
        <location>
            <begin position="239"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding; shared with dimeric partner" evidence="1">
        <location>
            <begin position="272"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="366"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD61280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="397" mass="42951" checksum="08E3CB53BA96AFF0" modified="2016-02-17" version="1">MSLTQHYADTLEEIRAAGLFKSERIITSPQSAQIELADGRNVLNFCANNYLGLADHPDIIQAAKDALDSHGFGMASVRFICGTQDLHKQLESTISDFFGKQDTILYAACFDANGGLFEPLLGENDAIISDALNHASIIDGVRLCKAKRFRYANCDMADLEKQLQAADAAGCKTKLITTDGVFSMDGFIAPLDEIVALAEKYGALVHIDECHATGFLGANGRGSAEVKGVLDRIDIITGTLGKAMGGALGGFTTAKKEVIELLRQRSRPYLFSNSLPPHVVAAGIKAFQMLAAAGDLRERLAQNTAYFRERMTAAGFDVKPGVHPISPVMLYDAPLAQKFAERLLEEGIYAIGFFFPVVPQGQARIRTQMSAAHTREHLDRAIDAFIKIGRELGVIGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE98</accession>
    <name>A0A0S2DE98_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56687">
        <property type="protein sequence ID" value="ALN56687"/>
        <property type="gene ID" value="GLE_1330"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1330"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1313"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="46" mass="4703" checksum="82E437C5B8D6D17E" modified="2016-02-17" version="1">MRVRRDAGRAERANGSRDASSWPTPSLVPGGRAGGGGRVSAARKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEC2</accession>
    <name>A0A0S2DEC2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1462</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56819">
        <property type="protein sequence ID" value="ALN56819"/>
        <property type="gene ID" value="GLE_1462"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1462"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1443"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="58" mass="6031" checksum="10F3C4A021312F5E" modified="2016-02-17" version="1">MDTAVGYESVGPEGPPTKAPKVISQKHRPHRPAVVGGASAPMLLPQVAAPHLIGKRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEH5</accession>
    <name>A0A0S2DEH5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Aquaporin Z</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10 12" type="primary">aqpZ</name>
        <name evidence="12" type="ORF">FE772_08380</name>
        <name evidence="11" type="ORF">GLE_1612</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946921.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1612"/>
    <dbReference type="EnsemblBacteria" id="ALN56969">
        <property type="protein sequence ID" value="ALN56969"/>
        <property type="gene ID" value="GLE_1612"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1612"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1592"/>
    <dbReference type="OMA" id="IFKALMY"/>
    <dbReference type="OrthoDB" id="1744995at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00333">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01146">
        <property type="entry name" value="Aquaporin_Z"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034294">
        <property type="entry name" value="Aquaporin_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023743">
        <property type="entry name" value="Aquaporin_Z"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45724">
        <property type="entry name" value="PTHR45724"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="SSF81338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00861">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="NPA 1" evidence="10">
        <location>
            <begin position="67"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="NPA 2" evidence="10">
        <location>
            <begin position="193"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="site" description="Involved in tetramerization or stability of the tetramer" evidence="10">
        <location>
            <position position="20"/>
        </location>
    </feature>
    <feature type="site" description="Selectivity filter" evidence="10">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <feature type="site" description="Selectivity filter" evidence="10">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <feature type="site" description="Selectivity filter" evidence="10">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="site" description="Selectivity filter" evidence="10">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN56969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW25680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="237" mass="23948" checksum="611CF7F03DCED1A8" modified="2016-02-17" version="1">MIKRLGAEFIGTFWLVLGGCGSAVLAANFGGAGNPLGIGLLGVALAFGLTVLTGAYALGHISGGHFNPAVSFGLWAGGRFPAKDLLPYIVAQVLGAILAGFVLFHIASGTGSFVIDPNAAGTFASNGYDLMSPGGYSASAAFLTEVVMTAMFLVIILGATHKNAPAGFAPIAIGLGLTLIHLISIPVTNTSVNPARSTGVALFAGAAALSQLWMFWVAPIVGGLIGGAVYRWLGKDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEI6</accession>
    <name>A0A0S2DEI6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_1628</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946933.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1628"/>
    <dbReference type="EnsemblBacteria" id="ALN56985">
        <property type="protein sequence ID" value="ALN56985"/>
        <property type="gene ID" value="GLE_1628"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1628"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1609"/>
    <dbReference type="OMA" id="KRLGEPW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="2"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="125"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="125"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN56985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="229" mass="24823" checksum="7F52A3ABA3F75D06" modified="2016-02-17" version="1">MRILLVEDESAIADTVLYALRAEGFEAVHCLTGGEALREVARAPFDLAVLDIGLPDIGGFALCRELRRGRDLPVIFLTAQNAEADRILGLEIGADDYVTKPFSPRELATRVRVVLRRAGVGNGGAGVAAAADPEPGFAHDPEGKRIRYRGQALDLTRYEYGLLAALLQRPGAVLSRAQLMDRVWGDALDSGDRTVDTHIKTLRAKLREIAAEADPIRTHRGLGYSLDNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEJ5</accession>
    <name>A0A0S2DEJ5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_19335</name>
        <name evidence="2" type="ORF">GLE_1392</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000055">
        <property type="protein sequence ID" value="OPD62293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56749">
        <property type="protein sequence ID" value="ALN56749"/>
        <property type="gene ID" value="GLE_1392"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62293">
        <property type="protein sequence ID" value="OPD62293"/>
        <property type="gene ID" value="BV903_19335"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1392"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1374"/>
    <dbReference type="OMA" id="PRCRTCR"/>
    <dbReference type="OrthoDB" id="1672336at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="219" mass="24426" checksum="58DDF88FAE19D428" modified="2016-02-17" version="1">MELDELKQAWQALGDKLDRQHRMERLRLREERGRRMRSGLRPLVWGQALQMAAGVLLTIWGAAFWSAHAHSAHLLAFGLALHLYGIALVVCGAWVQSCVAGIDYTAPVLALQRRLAALRRAYVRGGLAVGLAWWLLWMPALAAILMSLFGVDLYRNAPSMFVYGGAVGVAGLLASAWFLRWSRDPARPRLRRAVDDGVAGASVRRAEAVLEEIERFERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEQ0</accession>
    <name>A0A0S2DEQ0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Malonyl CoA-acyl carrier protein transacylase</fullName>
            <ecNumber evidence="2 5">2.3.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_1691</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>holo-[ACP] + malonyl-CoA = CoA + malonyl-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:41792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="EC" id="2.3.1.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the fabD family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.39" evidence="2 5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1691"/>
    <dbReference type="EnsemblBacteria" id="ALN57047">
        <property type="protein sequence ID" value="ALN57047"/>
        <property type="gene ID" value="GLE_1691"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1691"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1669"/>
    <dbReference type="OMA" id="AANYNCP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004314">
        <property type="term" value="F:[acyl-carrier-protein] S-malonyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024925">
        <property type="entry name" value="Malonyl_CoA-ACP_transAc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004410">
        <property type="entry name" value="Malonyl_CoA-ACP_transAc_FabD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000446">
        <property type="entry name" value="Mct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00128">
        <property type="entry name" value="fabD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_AT" evidence="7">
        <location>
            <begin position="11"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000446-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN57047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="315" mass="32857" checksum="6293C6792596ACBF" modified="2016-02-17" version="1">MRVSDQRLSFVFPGQGSQSLGMLAELSELHAGVRESFAEASDGAGVDLWALSQGGPDEMLNRTEYTQPALLAAGVAVWRLWQARGGAQPALLAGHSLGEYTALVAAGALSLRDGAHLVRLRGQLMQEAAPAGVGAMAAVLGAEDALVEEICQAVSGSEVVVPANYNSPGQIVIGGHAGAVDKALTRLAESGVRKAVKLAVSVPSHTPLMREAANRLAEAMAGLEWRLPGLPVVQNVDAQIHASVEAIRDALVRQLYLPVQWTGCVQALAAAGVQRTAECGPGKVLTGLVKRIDKSIDGRAIGTPAEFETALAEWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEU1</accession>
    <name>A0A0S2DEU1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1553</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56910">
        <property type="protein sequence ID" value="ALN56910"/>
        <property type="gene ID" value="GLE_1553"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1553"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="37" mass="3682" checksum="1FFBA0C898828022" modified="2016-02-17" version="1">MLVGHGDPGVGPARERRLGDAVGSTASAACCGRMAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF06</accession>
    <name>A0A0S2DF06_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1805</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57157">
        <property type="protein sequence ID" value="ALN57157"/>
        <property type="gene ID" value="GLE_1805"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1805"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1776"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="41" mass="4512" checksum="41B0A0A61ED10D83" modified="2016-02-17" version="1">MILRLFLLAAMGPEATAKSKWVPAFAGMTAMKQRCDEATVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF44</accession>
    <name>A0A0S2DF44_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heptosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1665"/>
    <dbReference type="EnsemblBacteria" id="ALN57022">
        <property type="protein sequence ID" value="ALN57022"/>
        <property type="gene ID" value="GLE_1665"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1665"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1644"/>
    <dbReference type="OMA" id="HMAVTQG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03789">
        <property type="entry name" value="GT9_LPS_heptosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002201">
        <property type="entry name" value="Glyco_trans_9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01075">
        <property type="entry name" value="Glyco_transf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="363" mass="39748" checksum="0F9C94F567EB5C7D" modified="2016-02-17" version="1">MNQSTPSSSTLPPAPALCLLRLSALGDVTHVVPLVRTLRKARPQASIAWIIGKGERRLLEGLEGVDFIEYDKKSGWAGMRALRRGLRERGLPGGRFDALLQMQVAARANLLSAFVPATRRIGYDRSRSKDLHGLFVNERIPDRPGIHVLDAIGSFCEPLGLRQTEVVWDLPVPDDAREWARAQWPDDGAPTLLVSPCSSHTLRNWRPERYAAVADHAAGLGWRVVMCGGRSQLERDTTDAILAAMTHPALDLVGKDTLKQLPALLERGQLLMTPDSGPMHIANAMGTKVLGLHAASNPARSGPYSDLRYCADRYDAAARKYLGKPAAQIAWGTKIEHDGVMDLIAVEDGIAAFERYRADHPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF72</accession>
    <name>A0A0S2DF72_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutamyl-Q tRNA(Asp) synthetase</fullName>
            <shortName evidence="5">Glu-Q-RSs</shortName>
            <ecNumber evidence="5">6.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">gluQ</name>
        <name evidence="9" type="ORF">GLE_1810</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1810"/>
    <dbReference type="EnsemblBacteria" id="ALN57162">
        <property type="protein sequence ID" value="ALN57162"/>
        <property type="gene ID" value="GLE_1810"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1810"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1781"/>
    <dbReference type="OMA" id="WLLRMED"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01428">
        <property type="entry name" value="Glu_Q_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022380">
        <property type="entry name" value="Glu-Q_tRNA(Asp)_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03838">
        <property type="entry name" value="queuosine_YadB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1c" evidence="8">
        <location>
            <begin position="23"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glutamate binding" evidence="5">
        <location>
            <begin position="25"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="5">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="5">
        <location>
            <begin position="248"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN57162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="322" mass="34453" checksum="D865A920AAAE3FCB" modified="2016-02-17" version="1">MSGHKHSIGGDNSDSEAATPSYRGRFAPSPTGDLHAGSLLAAFASWLLARRAGGEWLVRIEDLDPPREVPGAAQRQLDALAAFGLDSDLPVLRQSRRHAQYQAALDRLLAQDLAFACHCSRSDLAASGGVHRRCVAHGPRPGHAAPQPAVRLRVADGAVVEFDDLLLGRQRQDVAREVGDFVLRRADGHWAYQLAVVVDDAEQGVTDVVRGADLLDSTARQILLQRALRLPTPRYAHLPLLLDAHGRKLSKSEAAHPLDPADPLPALRAAWAALGQDARALVAVETVTQLLRAARDSFNPAQIPQAASGLAAMHNDPDANAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF79</accession>
    <name>A0A0S2DF79_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DUF1508 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_17250</name>
        <name evidence="5" type="ORF">FE772_09660</name>
        <name evidence="3" type="ORF">GLE_1887</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0339 family. Duplicated subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000046">
        <property type="protein sequence ID" value="OPD62680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947122.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000046.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1887"/>
    <dbReference type="EnsemblBacteria" id="ALN57239">
        <property type="protein sequence ID" value="ALN57239"/>
        <property type="gene ID" value="GLE_1887"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62680">
        <property type="protein sequence ID" value="OPD62680"/>
        <property type="gene ID" value="BV903_17250"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1887"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1857"/>
    <dbReference type="OrthoDB" id="1984963at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010879">
        <property type="entry name" value="DUF1508"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036913">
        <property type="entry name" value="YegP-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07411">
        <property type="entry name" value="DUF1508"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160113">
        <property type="entry name" value="SSF160113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1508" evidence="2">
        <location>
            <begin position="23"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD62680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="67" mass="7501" checksum="358622CF5CAB9710" modified="2016-02-17" version="1">MRFEIYRKGDDVLGNTPGTEDPYTWRLLADNDDILATGEGYANKTDCYHAINLVKSATTQTLVVDFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF96</accession>
    <name>A0A0S2DF96_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase</fullName>
            <ecNumber evidence="8 10">5.3.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">hisA</name>
        <name evidence="12" type="ORF">BV903_17310</name>
        <name evidence="13" type="ORF">FE772_09720</name>
        <name evidence="11" type="ORF">GLE_1902</name>
    </gene>
    <organism evidence="11 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">C3</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">B25</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8 10">
            <text>1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:15469"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="5.3.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8 10">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 4/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 8 9">Belongs to the HisA/HisF family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.16" evidence="8 10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000046">
        <property type="protein sequence ID" value="OPD62690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947131.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000046.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1902"/>
    <dbReference type="EnsemblBacteria" id="ALN57253">
        <property type="protein sequence ID" value="ALN57253"/>
        <property type="gene ID" value="GLE_1902"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62690">
        <property type="protein sequence ID" value="OPD62690"/>
        <property type="gene ID" value="BV903_17310"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1902"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1870"/>
    <dbReference type="OMA" id="EWLHLVD"/>
    <dbReference type="OrthoDB" id="794219at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00009"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003949">
        <property type="term" value="F:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04732">
        <property type="entry name" value="HisA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01014">
        <property type="entry name" value="HisA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006063">
        <property type="entry name" value="HisA_bact_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044524">
        <property type="entry name" value="Isoase_HisA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023016">
        <property type="entry name" value="Isoase_HisA-like_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43090">
        <property type="entry name" value="PTHR43090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00007">
        <property type="entry name" value="TIGR00007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7 8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN57253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OPD62690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW25901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="249" mass="27195" checksum="54084B4C3BF9BB4A" modified="2016-02-17" version="1">MGNSTLYPAIDVRDGRVVRLHQGDYAQETRYETEPLALATRYAEAGAKWLHLIDLDAARYGGYTLAPLLRAITTSSWMRVQTGGGVRSEADVEAILDAGADRVVVGSLAVKDPDLVIAWLKRFGSERITIALDVRQNERGEWELPVAGWTQDSGVRLEPLLERYAQAGLRHLLCTDVSRDGTMAGPNLDLYKHIREIAPDVQLQASGGIRDIADIVAADSIGCSGAVLGKALIEGRFQLTDALKQVRRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFE0</accession>
    <name>A0A0S2DFE0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Histidinol dehydrogenase</fullName>
            <shortName evidence="5">HDH</shortName>
            <ecNumber evidence="5">1.1.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 12" type="primary">hisD</name>
        <name evidence="12" type="ORF">GLE_1898</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + L-histidinol + 2 NAD(+) = 3 H(+) + L-histidine + 2 NADH</text>
            <dbReference type="Rhea" id="RHEA:20641"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5 10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 9/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6 11">Belongs to the histidinol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.23" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1898"/>
    <dbReference type="EnsemblBacteria" id="ALN57249">
        <property type="protein sequence ID" value="ALN57249"/>
        <property type="gene ID" value="GLE_1898"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1898"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1866"/>
    <dbReference type="OMA" id="MVTGPGN"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00014"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004399">
        <property type="term" value="F:histidinol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06572">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01024">
        <property type="entry name" value="HisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001692">
        <property type="entry name" value="Histidinol_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022695">
        <property type="entry name" value="Histidinol_DH_monofunct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012131">
        <property type="entry name" value="Hstdl_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256">
        <property type="entry name" value="PTHR21256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00815">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000099">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00083">
        <property type="entry name" value="HOLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00069">
        <property type="entry name" value="hisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00611">
        <property type="entry name" value="HISOL_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="2 5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0520">NAD</keyword>
    <keyword evidence="4 5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 10" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5 7">
        <location>
            <position position="336"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5 7">
        <location>
            <position position="337"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 9">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 9 10">
        <location>
            <position position="269"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 9 10">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 9">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 9 10">
        <location>
            <position position="370"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 9">
        <location>
            <position position="424"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 9 10">
        <location>
            <position position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN57249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="452" mass="46975" checksum="58C909DD6C43F497" modified="2016-02-17" version="1">MNLPATAAAMQRYQWGALSADARAQALRRPAQETRQATADAVAAILAEVRADGDAALRRFGQRFDGVAPESFAVGQAEFEAADAALSAQLRAAIDEAARRIERFHAAGMTPAYALDTAEGVRCERVLRPIPRVGLYVPAGSAPLPSTALMLGVPARLAGCREVVLCTPPRKDGSADPAVLYAARRCGIGKVYKVGGAQAIAAMAFGSDSIGKCDKLFGPGNAYVTEAKRQVALLEGGAAIDMPAGPSEVLVIADAGARADFVAADLLSQAEHGADSQVILLSDDAALLDAVDVELERQLARLSRADTARAALAKSRSIQVDSIASAMQVSNRYAPEHLILALRDARAWLAQVEAAGSVFLGDWAPEALGDYCSGTNHVLPTSGAARYAGGLNVASFQVAITVQEVQPRGLQEIGPCAVVLAQAEGLDAHREAVALRLAALAEAEAATPAQRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFF8</accession>
    <name>A0A0S2DFF8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Two component heavy metal response transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_09160</name>
        <name evidence="5" type="ORF">GLE_1780</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947045.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1780"/>
    <dbReference type="EnsemblBacteria" id="ALN57134">
        <property type="protein sequence ID" value="ALN57134"/>
        <property type="gene ID" value="GLE_1780"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1780"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1754"/>
    <dbReference type="OMA" id="GHVVECS"/>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006291">
        <property type="entry name" value="PcoR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01387">
        <property type="entry name" value="cztR_silR_copR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="2"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="123"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="123"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW25808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="235" mass="26373" checksum="6C6E58A6121E72F0" modified="2016-02-17" version="1">MKLLIVEDEAKTADYLRDGLAEQGWSVDVARDGNSGLHLAREFDYDVIVLDVMLPGLDGFSVLRELRLRKQTPVIMLTARDRIDDRVHGLGAGADDYLVKPFSFIELLARLQALVRRGRQQESTELNIGDLQINLLARRAFRDGNRLDLTGKEFALLALLAQRRGQILSKTVIAAQVWDINFDSNTNVVEVAIKRLRAKIDGPFRNKLLHTVRGMGYVLETREDEDAAANARPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFK5</accession>
    <name>A0A0S2DFK5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FeoA domain</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Ferrous iron transport protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_09935</name>
        <name evidence="4" type="ORF">GLE_1955</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FeoA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947167.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1955"/>
    <dbReference type="EnsemblBacteria" id="ALN57306">
        <property type="protein sequence ID" value="ALN57306"/>
        <property type="gene ID" value="GLE_1955"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1955"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1920"/>
    <dbReference type="OMA" id="VQIIAYG"/>
    <dbReference type="OrthoDB" id="2047422at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007167">
        <property type="entry name" value="Fe-transptr_FeoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038157">
        <property type="entry name" value="FeoA_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008988">
        <property type="entry name" value="Transcriptional_repressor_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04023">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00899">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50037">
        <property type="entry name" value="SSF50037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeoA" evidence="3">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="84" mass="9101" checksum="79D02B380112D4A3" modified="2016-02-17" version="1">MKLSELPRRIAATVETVDDQAPNDTIARRLRELGFVAGERVEVMAAGPVAAEPLLVQIGYTRFALRRSEAARVRVKPLSAEGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFM2</accession>
    <name>A0A0S2DFM2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1979</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57329">
        <property type="protein sequence ID" value="ALN57329"/>
        <property type="gene ID" value="GLE_1979"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1979"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1944"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046116">
        <property type="entry name" value="DUF6053"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19523">
        <property type="entry name" value="DUF6053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="63" mass="6655" checksum="3AF0D26AD90BD7AA" modified="2016-02-17" version="1">MTAARRPAKWRAGRKWRRRPAASVFVGGPSGPTLSDRIAAIRNDSVGPEGPPTNARAAGETSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFS7</accession>
    <name>A0A0S2DFS7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2012</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2012"/>
    <dbReference type="EnsemblBacteria" id="ALN57362">
        <property type="protein sequence ID" value="ALN57362"/>
        <property type="gene ID" value="GLE_2012"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2012"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1977"/>
    <dbReference type="OrthoDB" id="958405at1224"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594768" evidence="1">
        <location>
            <begin position="28"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="170" mass="17495" checksum="C361599B7A79C522" modified="2016-02-17" version="1">MKARTLVAALALSALSTLFGAAGCARAPDGTVDPLAGAQPVRGDVAFYLVAEDGAADARTLPVLRPFPGQEPRVALKPMPAIARGQIAQVALSTDENGQASLDLRLNEEGARRLAQITRDNLGKRMAVVVGATAVSVATIQGEIPGGRLRIGGLAQGDAQALHRELTVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFU8</accession>
    <name>A0A0S2DFU8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PqaA protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pqaA</name>
        <name evidence="4" type="ORF">FE772_10390</name>
        <name evidence="3" type="ORF">GLE_2051</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947244.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2051"/>
    <dbReference type="EnsemblBacteria" id="ALN57401">
        <property type="protein sequence ID" value="ALN57401"/>
        <property type="gene ID" value="GLE_2051"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2051"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2016"/>
    <dbReference type="OMA" id="VPKYIVN"/>
    <dbReference type="OrthoDB" id="505680at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009199">
        <property type="entry name" value="PhoPQ-act_pathogen-rel_PqaA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31497">
        <property type="entry name" value="PTHR31497"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10142">
        <property type="entry name" value="PhoPQ_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF014728">
        <property type="entry name" value="PqaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242138" evidence="2">
        <location>
            <begin position="28"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="507" mass="55475" checksum="8B4A57353C22681C" modified="2016-02-17" version="1">MKPPRFARYVPTLACVAALAACASLHAAAPAAQRAPTADFGQAWPEYRQRQSRLPLRYEAIERVRLDGAERRSYRLYSQSWPESGGADPAQWSHRVDLYVPDAARPKSALLVINNGTNRGNGSDPQRPPSDFSEELARETAVATQTIVVSVSDAPNQYLALPGEPPRKEDALVAATWRRFLDEPVASNATLPLHVPMAEAAVKAMDLAQRELAPYRLRSFVVTGASKRAWAAWLTAIGDARVGAIVSYVIDMRIAPLIGHIGRVYGGGWPIALQPYYQEGITRRYQEPAFARLMQVDDPYSYLAGRHRARLGIPKYLVSASGDDFFPPDAQRLYVDDLPGATALRAAPNSNHGGIRDHIRTTLIPALQRWNRHQALPQVRARLGERDGALRLSARASERPVSARLWLAENPDSRDFRYACGVRYREQPLDLRRNAVEAALAKPARGWGAAFVEFAFADGFVATSPVFVYPDAQFPNQPPPNGSGACLVLPPHAPTHAPAAAPAAANG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFV8</accession>
    <name>A0A0S2DFV8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 12">Aspartate-semialdehyde dehydrogenase</fullName>
            <shortName evidence="12">ASA dehydrogenase</shortName>
            <shortName evidence="12">ASADH</shortName>
            <ecNumber evidence="7 12">1.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Aspartate-beta-semialdehyde dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12 14" type="primary">asd</name>
        <name evidence="15" type="ORF">FE772_10815</name>
        <name evidence="14" type="ORF">GLE_2142</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">C3</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho-L-aspartate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:24284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.2.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 12">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 12">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the aspartate-semialdehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.11" evidence="7 12"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947312.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2142"/>
    <dbReference type="EnsemblBacteria" id="ALN57492">
        <property type="protein sequence ID" value="ALN57492"/>
        <property type="gene ID" value="GLE_2142"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2142"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2106"/>
    <dbReference type="OMA" id="CEEEMKM"/>
    <dbReference type="OrthoDB" id="1799040at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00016"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00463"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00464"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004073">
        <property type="term" value="F:aspartate-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071266">
        <property type="term" value="P:'de novo' L-methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02121">
        <property type="entry name" value="ASADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012080">
        <property type="entry name" value="Asp_semialdehyde_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005986">
        <property type="entry name" value="Asp_semialdehyde_DH_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01296">
        <property type="entry name" value="asd_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 12" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="11 12" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="12" id="KW-0521">NADP</keyword>
    <keyword evidence="12 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="13">
        <location>
            <begin position="8"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="12">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="15"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="43"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="163"/>
            <end position="164"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN57492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW26088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="340" mass="36371" checksum="5E1EEE2A90AC4C9C" modified="2016-02-17" version="1">MNAKTSCNVAVVGATGAVGETMLKVLAERKFPIGKLHVLASERSAGEKIEFEGQTLVVEDLAAFDPKGVDIALFSAGGSVSKEYAPKFAAAGAVVIDNSSAFRYQDDVPLVVSEVNPEALKNRPLGIVANPNCSTMQLMVALAPIHRQAKLERINIATYQSVSGTGKRAMEELGRQTAALLSFQEAQPEIYPVQIAFNVIPHGGDFTDNGYTTEEMKLVWETRKILGDDSIGVNATVVRVPVFYGHSEAVHIETRDKLSAADARALLEKAPGLVVVDEAKGGGYPTPVTHASGEDPVFVGRVRDDISHPRGLSLWVVADNIRKGAATNAVQLAELVWAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG16</accession>
    <name>A0A0S2DG16_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH-quinone oxidoreductase subunit H</fullName>
            <ecNumber evidence="5">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">NADH dehydrogenase I subunit H</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">NDH-1 subunit H</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">nuoH</name>
        <name evidence="7" type="ORF">GLE_2166</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cell membrane</location>
            <topology evidence="5 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the complex I subunit 1 family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2166"/>
    <dbReference type="EnsemblBacteria" id="ALN57516">
        <property type="protein sequence ID" value="ALN57516"/>
        <property type="gene ID" value="GLE_2166"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2166"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2129"/>
    <dbReference type="OMA" id="MYVGMGI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01350">
        <property type="entry name" value="NDH1_NuoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001694">
        <property type="entry name" value="NADH_UbQ_OxRdtase_su1/FPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018086">
        <property type="entry name" value="NADH_UbQ_OxRdtase_su1_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11432">
        <property type="entry name" value="PTHR11432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00146">
        <property type="entry name" value="NADHdh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00668">
        <property type="entry name" value="COMPLEX1_ND1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0874">Quinone</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="200"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="354" mass="39275" checksum="C5F858BE463C51DE" modified="2016-02-17" version="1">MFMTQLVDPLHNWFLSLGMVGAVLWIVLKILLIAMPVIITVAFYVVWERKLIGWMHVRHGPMYVGMGILQAFADVFKLLFKEVIQPAKAESFLYKLAPLLTLAPAFAAWAVVPFDAKLVLSNANAGLLYLLAMTSLGVYGIILAGWASNSKYAFLGAMRAAAQVVSYEIAMGFAMVGVMVGAGSLNLTDIVMAQSGNAGALEWFALPMLPLFVVYFISGVAETNRAPFDVVEGESEIVAGHMVEYSGSAFALFFLAEYANMILISFLTSIFFVGGWLSPFQGLGIPFLSVDGWWWLLAKVFFFASCFIWFRASFPRYRYDQIMRLGWKVFIPLTIAWIVVVALMSYYGIFLPGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG25</accession>
    <name>A0A0S2DG25_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-binding transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Trp operon repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_17280</name>
        <name evidence="4" type="ORF">D9T17_17900</name>
        <name evidence="3" type="ORF">FE772_09690</name>
        <name evidence="1" type="ORF">GLE_1896</name>
    </gene>
    <organism evidence="1 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 5">C3</strain>
        </source>
    </reference>
    <reference evidence="2 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">OH11</strain>
        </source>
    </reference>
    <reference evidence="3 8" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000046">
        <property type="protein sequence ID" value="OPD62685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000044">
        <property type="protein sequence ID" value="ROU05571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947126.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000044.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1896"/>
    <dbReference type="EnsemblBacteria" id="ALN57247">
        <property type="protein sequence ID" value="ALN57247"/>
        <property type="gene ID" value="GLE_1896"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62685">
        <property type="protein sequence ID" value="OPD62685"/>
        <property type="gene ID" value="BV903_17280"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1896"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1864"/>
    <dbReference type="OMA" id="DECYRFF"/>
    <dbReference type="OrthoDB" id="1926997at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000831">
        <property type="entry name" value="Trp_repress"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038116">
        <property type="entry name" value="TrpR-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013368">
        <property type="entry name" value="YecD_YerC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40080">
        <property type="entry name" value="PTHR40080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01371">
        <property type="entry name" value="Trp_repressor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF012508">
        <property type="entry name" value="YerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="SSF48295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02531">
        <property type="entry name" value="yecD_yerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD62685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROU05571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="104" mass="11477" checksum="A300467CB6F8FC12" modified="2016-02-17" version="1">MKRRAVATVEATEDALGELAAALSALRAPEQVRAFLEDLCTPAELEAMSDRWRVVPLLDEGVPYREIHERTQVSVTTIGRVARVLERGAGGYAAALQRRGPRHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGF8</accession>
    <name>A0A0S2DGF8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase, families S8 and S53</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_1993</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947195.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1993"/>
    <dbReference type="EnsemblBacteria" id="ALN57343">
        <property type="protein sequence ID" value="ALN57343"/>
        <property type="gene ID" value="GLE_1993"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1993"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1960"/>
    <dbReference type="OMA" id="YIAMEYW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
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    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594778" evidence="4">
        <location>
            <begin position="24"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="5">
        <location>
            <begin position="237"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="500" mass="51780" checksum="88A54C7F1AA10186" modified="2016-02-17" version="1">MRSIAHSRPTLLLRALLPCLALAAIPAVAAAASPSNPTAPQVLLSKPIKTQLGRYDSREFIEVKFVDDSRVSLHGNRLSSAKFGRLAALEGLTGGAGPVAALEPLFRADAATLQALAKSAQTADSQPDLSQWFRLRVKPGQDIARVIDELNAMSIVETAYAAPLPVAPPASPAYHDFQTYKLPAAQSGIDSDYARTVAGGNGAGIRVLDVEYSWNTNHEDLSKLRLAGARINNGTPSDPFNDNNHGTAVMGQLVADNNGIGVTGLVDGASAHVTNAMNTERGYDPANAILTAANALRAGDVILIEQQAAGPSACNGYVPTEWIPSVHAAIVTATNKGIHVVQAGGNGNMNLDNTACFGSPFPGGRADSGAIIVGAGGPRSIIWCSDSVAERAKQPFSSYGSRVNVQAWGRCVTTTGYGNLYNGGVNAYYTKTFSGTSSASPIVAAAVVALSGIAKQRGITLTPRQMRDLLKNTGTPQAGGGGNIGPLPNLRAAIAQLGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGT3</accession>
    <name>A0A0S2DGT3_LYSEN</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2388</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57737">
        <property type="protein sequence ID" value="ALN57737"/>
        <property type="gene ID" value="GLE_2388"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2388"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2350"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="46" mass="5132" checksum="A231C61F82BF450D" modified="2016-02-17" version="1">MKKTIDMPLIVKSGVRLIEPTSTLEAHDVQPEITADELDFLEAHAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH05</accession>
    <name>A0A0S2DH05_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Transporter, major facilitator family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_13100</name>
        <name evidence="7" type="ORF">GLE_2610</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947675.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2610"/>
    <dbReference type="EnsemblBacteria" id="ALN57958">
        <property type="protein sequence ID" value="ALN57958"/>
        <property type="gene ID" value="GLE_2610"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2610"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2570"/>
    <dbReference type="OMA" id="GQIGMAF"/>
    <dbReference type="OrthoDB" id="791272at2"/>
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    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004740">
        <property type="entry name" value="Nuc_H_symport"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
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        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="115"/>
        </location>
    </feature>
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        <location>
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            <end position="153"/>
        </location>
    </feature>
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            <end position="181"/>
        </location>
    </feature>
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        <location>
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            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="359"/>
        </location>
    </feature>
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        <location>
            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="162"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW26462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="409" mass="43974" checksum="179E8E5BC6BD9461" modified="2016-02-17" version="1">MTFTMPRLSAMMFLQFFIWGAWFVTLGTYLVQGPLQASASQVATAFLSQSIGAIVAPFLVGLIADRYFAAQRILALLHLAGAALMWGASTATSFGAFSACVMAYMLLFMPTLALANSIAMRHMQAPEKQFPPVRVAGSIGWIVAGVLIGWLGWEQAHRLDLTFKMAAAASLLLGLYALTLPHTPPLERQREAGLGQILGLDALRLLKSRSYLVFFLASIAICIPLSFYYNFTNPYLNDLGVRGAAGLQSLGQVSEVLLMLAMPFLFARLGVKTMLALGMAAWVLRYVLFAYGDAGAGFALLVTGIVLHGICYDFFFVTGQIYTDAHAGPAFRSSAQGFITLATYGVGMLIGSFLSGAVVEHYTTAAGRDWQQIWLFPAGVALLVLAAFLLLFRERPAAVSAAPPTPSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH16</accession>
    <name>A0A0S2DH16_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2334</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947461.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2334"/>
    <dbReference type="EnsemblBacteria" id="ALN57683">
        <property type="protein sequence ID" value="ALN57683"/>
        <property type="gene ID" value="GLE_2334"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2334"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2298"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="114" mass="11977" checksum="0C207E8725688AE7" modified="2016-02-17" version="1">MMLALCAVAAALPAQRRILPASQPAPPPCVQVRIGHDEAGRWDCVNAAIKTEVGKTAPVSAADSPGERLAPIGQGLAVPAATRQRLGDQYGKSIVPQRPERVFPATPLSRPPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH42</accession>
    <name>A0A0S2DH42_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_13055</name>
        <name evidence="4" type="ORF">GLE_2600</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57948">
        <property type="protein sequence ID" value="ALN57948"/>
        <property type="gene ID" value="GLE_2600"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2600"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2560"/>
    <dbReference type="OMA" id="ANTMTEQ"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726656" evidence="3">
        <location>
            <begin position="32"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="175"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="231"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="380"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="288"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="429" mass="46338" checksum="B5D4B0C7D4A284EB" modified="2016-02-17" version="1">MPDLARHRLIPACVLGLALLYGMTAPASALASGAQDDAAPAAAVGASPGGPAPALTPTLAPAPAPAPKVSAVDGVLQLDDIAEVTVANLKEWAATHDPAKLVPFIDGRAIRGNYPEEVHPHEGRIYFHLKITPESKEHWTDLLGAPDSMRRPVRFSIGLEDHAPFETVHDKTNPLLMTVISPVFGATAALVASLTLILFIRLARSTSIIREPGAAPADGSPKAYNLGRTQMAFWFFLIYVSYLVIWLITDMLDTITPSLLGLMGISAGTALSEALIDSSKDSAHSERRWNLSAERRELEKTIADLKLERAGLDAGAAATPDEIAQRERLDGKIQAARARLTQATHRFSSLDSKKSARASRGFLRDVMADRDGYSFHRFQIFAWTIVLGIMFVSSVYNSLAMPEFSATLLGLMGLSSGTYIGFKFPERQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHE1</accession>
    <name>A0A0S2DHE1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-glucosidase</fullName>
            <ecNumber evidence="4">3.2.1.21</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_2523</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.21" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2523"/>
    <dbReference type="EnsemblBacteria" id="ALN57872">
        <property type="protein sequence ID" value="ALN57872"/>
        <property type="gene ID" value="GLE_2523"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2523"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2485"/>
    <dbReference type="OMA" id="TLITDWD"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102483">
        <property type="term" value="F:scopolin beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="SSF52279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fn3_like" evidence="3">
        <location>
            <begin position="632"/>
            <end position="701"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="734" mass="79213" checksum="4190AF5C7A2DB974" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHE7</accession>
    <name>A0A0S2DHE7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Biopolymer transporter ExbD</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Transport energizing protein, ExbD/TolR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BV903_01975</name>
        <name evidence="11" type="ORF">D9T17_14070</name>
        <name evidence="10" type="ORF">FE772_11685</name>
        <name evidence="8" type="ORF">GLE_2330</name>
    </gene>
    <organism evidence="8 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 12">C3</strain>
        </source>
    </reference>
    <reference evidence="9 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">OH11</strain>
        </source>
    </reference>
    <reference evidence="10 15" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 15">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000004">
        <property type="protein sequence ID" value="OPD65560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000034">
        <property type="protein sequence ID" value="ROU06370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947457.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2330"/>
    <dbReference type="EnsemblBacteria" id="ALN57679">
        <property type="protein sequence ID" value="ALN57679"/>
        <property type="gene ID" value="GLE_2330"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65560">
        <property type="protein sequence ID" value="OPD65560"/>
        <property type="gene ID" value="BV903_01975"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2330"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2294"/>
    <dbReference type="OMA" id="MIDIMMF"/>
    <dbReference type="OrthoDB" id="1940365at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30558">
        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN57679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD65560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW26233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROU06370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="134" mass="14288" checksum="A3FA7F217FA9231C" modified="2016-02-17" version="1">MKVQGKKPYDDINITPMLDLAYVLLVIFIIMTTAAVQGIKVDLPKASAAQPLSQPKTKVIAIDNAGQVSIDAVPVSMSELEQQLRNALANDAELPVILRGDRAVQYDKVMAVLDLCSKLGISSIGLASQRQAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHF4</accession>
    <name>A0A0S2DHF4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Polyketide synthase pksM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLE_2494</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947581.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2494"/>
    <dbReference type="EnsemblBacteria" id="ALN57843">
        <property type="protein sequence ID" value="ALN57843"/>
        <property type="gene ID" value="GLE_2494"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2494"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2457"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="9">
        <location>
            <begin position="961"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="9">
        <location>
            <begin position="2902"/>
            <end position="2978"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="9">
        <location>
            <begin position="3026"/>
            <end position="3099"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="9">
        <location>
            <begin position="4528"/>
            <end position="4604"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="9">
        <location>
            <begin position="5320"/>
            <end position="5397"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="9">
        <location>
            <begin position="5453"/>
            <end position="5530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1049"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="2851"/>
            <end position="2889"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="4488"/>
            <end position="4527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="4623"/>
            <end position="4658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="5297"/>
            <end position="5318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="5400"/>
            <end position="5423"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="7">
        <location>
            <position position="1000"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="7">
        <location>
            <position position="2939"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="7">
        <location>
            <position position="3060"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="7">
        <location>
            <position position="4565"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="7">
        <location>
            <position position="5357"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="7">
        <location>
            <position position="5490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN57843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="5579" mass="588907" checksum="41A3605F9FF7A6A8" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI41</accession>
    <name>A0A0S2DI41_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58098">
        <property type="protein sequence ID" value="ALN58098"/>
        <property type="gene ID" value="GLE_2750"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2750"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="75" mass="8094" checksum="ABBCC3B5C8D61314" modified="2016-02-17" version="1">MGPIPTQKQALGGVFQLRCNIRGGPCARAARDVRRGRGKSRFPIPIARPRPRSRPAPATPARGASRRPGKRAQVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIA0</accession>
    <name>A0A0S2DIA0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CDP-diacylglycerol--serine O-phosphatidyltransferase</fullName>
            <ecNumber evidence="3">2.7.8.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pssA</name>
        <name evidence="4" type="ORF">FE772_14280</name>
        <name evidence="3" type="ORF">GLE_2860</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.8" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947868.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2860"/>
    <dbReference type="EnsemblBacteria" id="ALN58208">
        <property type="protein sequence ID" value="ALN58208"/>
        <property type="gene ID" value="GLE_2860"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2860"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2822"/>
    <dbReference type="OMA" id="CGMISKS"/>
    <dbReference type="OrthoDB" id="1232102at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003882">
        <property type="term" value="F:CDP-diacylglycerol-serine O-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="204" mass="22201" checksum="757EE1123C1FF55C" modified="2016-02-17" version="1">MPRHFSMLREFHLADWFTLANAFCGTGAIFAAMRFLQDGDVRNLMIGMALIPLAFVFDALDGRVARWRKSSSTLGRELDSLADVISFGVAPAALAYACGLQGGWDWVVLSYFVGCGVSRLARYNVTAEALAGDEGKVKYFEGTPIPTSLLLVIVLAVAAWQGAIGENLWFGGVRVGPWLFHPLVLMFALSGSLMISKTLRIPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIB9</accession>
    <name>A0A0S2DIB9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome c-type biogenesis protein CcmE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Cytochrome c maturation protein E</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Heme chaperone CcmE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 8" type="primary">ccmE</name>
        <name evidence="4" type="synonym">cycJ</name>
        <name evidence="9" type="ORF">FE772_14135</name>
        <name evidence="8" type="ORF">GLE_2830</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CcmE/CycJ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947846.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2830"/>
    <dbReference type="EnsemblBacteria" id="ALN58178">
        <property type="protein sequence ID" value="ALN58178"/>
        <property type="gene ID" value="GLE_2830"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2830"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2788"/>
    <dbReference type="OMA" id="HVEFAVH"/>
    <dbReference type="OrthoDB" id="1724595at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017003">
        <property type="term" value="P:protein-heme linkage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01959">
        <property type="entry name" value="CcmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004329">
        <property type="entry name" value="CcmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036127">
        <property type="entry name" value="CcmE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34128">
        <property type="entry name" value="PTHR34128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03100">
        <property type="entry name" value="CcmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82093">
        <property type="entry name" value="SSF82093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2 4" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="1 4 5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242188" description="Cytochrome c-type biogenesis protein CcmE" evidence="7">
        <location>
            <begin position="25"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="4">
        <location>
            <begin position="1"/>
            <end position="8"/>
        </location>
    </feature>
    <feature type="topological domain" description="Extracellular" evidence="4">
        <location>
            <begin position="30"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="4 5">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="4 5">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604329-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW26629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="155" mass="16565" checksum="76BF4701325379E0" modified="2016-02-17" version="1">MNPTRRRRLLWVLGLVAAAGAATALVATALQRNIAYLYTPSEVLRGEAGGHARFRLGGMVAAGSFQRTTGSLDASFRVTDGDAQVPVKYTGILPDLFREKQAVVATGRMQGDTFVAEEILAKHDESYMPKEVADKMGQAHKKHDVAAPGGAEAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIC4</accession>
    <name>A0A0S2DIC4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2804</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58152">
        <property type="protein sequence ID" value="ALN58152"/>
        <property type="gene ID" value="GLE_2804"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2804"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2761"/>
    <dbReference type="OrthoDB" id="1712553at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="242" mass="25398" checksum="2939E072A119A91B" modified="2016-02-17" version="1">MTFDITWNRPMNPHSHRLSILAALLTLALVGCDRQASAPSSPVAPADGAAGSSPASARPDSPSPASSVPAQAAAMNNEIPQGFSSYASESIGDNKQCVAGAASDEDGMNQRPVAYLAQASGKPIWTRTLDLPADTYQSRATHCLRQGDALYVLLQSDTQPEQSLSQTLLRVVKLNLADGAVQAGGDVVVPGAQGAYSALAEEGAKHLRWDNGNVVVSGQYFQLDAPDQRRDFSTTLKPDLGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ10</accession>
    <name>A0A0S2DJ10_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">N-acetyltransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_14625</name>
        <name evidence="2" type="ORF">GLE_2932</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947921.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2932"/>
    <dbReference type="EnsemblBacteria" id="ALN58280">
        <property type="protein sequence ID" value="ALN58280"/>
        <property type="gene ID" value="GLE_2932"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2932"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2894"/>
    <dbReference type="OMA" id="YRERHAY"/>
    <dbReference type="OrthoDB" id="1809950at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="190" mass="20526" checksum="2C9233906894627A" modified="2016-02-17" version="1">MAAAAPPLRLRAAVESDLDAIAALYALEVREGVATYEYDVPDRSEMRRRWRAIVEAGYPYLVAERIEDGAARFAGYAYASAYRTRIGYRWTVENSVYVEPASHGCGIGGALMRRLIADCTALGFRQMVAVIGDGSNAASVALHERLGFKLAGVFPGLGRKHGRWLDTVQMVLPLGDGDVGEPDPGVPGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ55</accession>
    <name>A0A0S2DJ55_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phosphate ABC transporter ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Phosphate ABC transporter ATP-binding protein PstB</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Phosphate ABC transporter, ATP-binding protein</fullName>
            <ecNumber evidence="6">3.6.3.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pstB</name>
        <name evidence="7" type="ORF">BV903_20465</name>
        <name evidence="8" type="ORF">FE772_16405</name>
        <name evidence="6" type="ORF">GLE_3317</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">C3</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.3.27" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000062">
        <property type="protein sequence ID" value="OPD62058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948203.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000062.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3317"/>
    <dbReference type="EnsemblBacteria" id="ALN58663">
        <property type="protein sequence ID" value="ALN58663"/>
        <property type="gene ID" value="GLE_3317"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62058">
        <property type="protein sequence ID" value="OPD62058"/>
        <property type="gene ID" value="BV903_20465"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3317"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3267"/>
    <dbReference type="OMA" id="TIDICRV"/>
    <dbReference type="OrthoDB" id="1416748at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015415">
        <property type="term" value="F:ATPase-coupled phosphate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03260">
        <property type="entry name" value="ABC_PstB_phosphate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015850">
        <property type="entry name" value="ABC_transpr_PstB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005670">
        <property type="entry name" value="Phosp_transpt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423">
        <property type="entry name" value="PTHR43423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423:SF3">
        <property type="entry name" value="PTHR43423:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00972">
        <property type="entry name" value="3a0107s01c2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="28"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="60"/>
            <end position="67"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD62058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW26983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="274" mass="30636" checksum="E288344E275C6442" modified="2016-02-17" version="1">MNDARSSDARLSVATPSREAAGANPVKLAARDLNFYYDKFHALKSINLEIPEKQVTALIGPSGCGKSTLLRIFNRIYALYPKLEARGQVLLDGENILDPKYPMNRLRSKVGMVFQKPVPFPMTIFENVAYGIRHHEKLSKSEMNDRVEQALRQGALWDEVKDKLGQSALGLSGGQQQRLCIARAVALRPSVLLLDEPTSALDPISTSRIEQLVEELKKDYTIAIVTHNMQQAARVSDFTAFMYLGDLIEHGPTEQIFSKPTKQQTEDYITGRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJC3</accession>
    <name>A0A0S2DJC3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MarR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_24595</name>
        <name evidence="5" type="ORF">D9T17_11890</name>
        <name evidence="4" type="ORF">FE772_16150</name>
        <name evidence="2" type="ORF">GLE_3262</name>
    </gene>
    <organism evidence="2 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">C3</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 9" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000096">
        <property type="protein sequence ID" value="OPD61255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000029">
        <property type="protein sequence ID" value="ROU06809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948160.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000029.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3262"/>
    <dbReference type="EnsemblBacteria" id="ALN58608">
        <property type="protein sequence ID" value="ALN58608"/>
        <property type="gene ID" value="GLE_3262"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61255">
        <property type="protein sequence ID" value="OPD61255"/>
        <property type="gene ID" value="BV903_24595"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3262"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3215"/>
    <dbReference type="OMA" id="MICPATT"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023187">
        <property type="entry name" value="Tscrpt_reg_MarR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01117">
        <property type="entry name" value="HTH_MARR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="12"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU06809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="152" mass="16810" checksum="C1D50100147EBB9E" modified="2016-02-17" version="1">MTTPTPTQPCSTSNLGLLFRQVRDAMWAQMERELAQAGHDLTFSQFITLKELAIGTAGVTELARAAQLNPGAMTRLLDKLESRGLVARVADPDDRRALNIHLTEAGTAIWADIDQCGRRVRERAMSGLSDSDREQLYRLLEQVRDNLSLSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJE0</accession>
    <name>A0A0S2DJE0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">UvrABC system protein A</fullName>
            <shortName evidence="13">UvrA protein</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Excinuclease ABC subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 17" type="primary">uvrA</name>
        <name evidence="18" type="ORF">FE772_16315</name>
        <name evidence="17" type="ORF">GLE_3297</name>
    </gene>
    <organism evidence="17 19">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="17 19" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">C3</strain>
        </source>
    </reference>
    <reference evidence="18 20" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 20">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Forms a heterotetramer with UvrB during the search for lesions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the ABC transporter superfamily. UvrA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948188.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3297"/>
    <dbReference type="EnsemblBacteria" id="ALN58643">
        <property type="protein sequence ID" value="ALN58643"/>
        <property type="gene ID" value="GLE_3297"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3297"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3247"/>
    <dbReference type="OMA" id="PFEGIIP"/>
    <dbReference type="OrthoDB" id="152379at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00205">
        <property type="entry name" value="UvrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004602">
        <property type="entry name" value="UvrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041552">
        <property type="entry name" value="UvrA_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041102">
        <property type="entry name" value="UvrA_inter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17755">
        <property type="entry name" value="UvrA_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17760">
        <property type="entry name" value="UvrA_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00630">
        <property type="entry name" value="uvra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 13" id="KW-0228">DNA excision</keyword>
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        <location>
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            <end position="938"/>
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            <end position="282"/>
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            <end position="767"/>
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            <begin position="947"/>
            <end position="992"/>
        </location>
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        <location>
            <begin position="33"/>
            <end position="40"/>
        </location>
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        <location>
            <begin position="642"/>
            <end position="649"/>
        </location>
        <ligand>
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        <source>
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        <source>
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        </source>
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        </source>
    </evidence>
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        <source>
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        </source>
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        <source>
            <dbReference type="PROSITE" id="PS50893"/>
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        </source>
    </evidence>
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        <source>
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    <sequence length="992" mass="109027" checksum="37C917C35F2B48D5" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJE2</accession>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
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            </authorList>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="169" mass="17283" checksum="9E28926B08095123" modified="2016-02-17" version="1">MNTKNIRLLGVAAAASLALAGCATSPGYGGGGYGGGGYNNYPQQPQPGYGDQNRCYDCGVVTRIEQISTQGTAPSATGAVLGGLVGAVAGRKIADDHTDSKGRKNSATVAGAVAGAVAGNAIQNRVGAPSYNVYVRMDDGRTQVVTQKDLDGIRENTYVRVANGRAYIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJF2</accession>
    <name>A0A0S2DJF2_LYSEN</name>
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        <submittedName>
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        <submittedName>
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        <name evidence="7" type="ORF">BV903_24585</name>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">C3</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
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        <property type="protein sequence ID" value="ALN58610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD61253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW26941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948162.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000096.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3264"/>
    <dbReference type="EnsemblBacteria" id="ALN58610">
        <property type="protein sequence ID" value="ALN58610"/>
        <property type="gene ID" value="GLE_3264"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61253">
        <property type="protein sequence ID" value="OPD61253"/>
        <property type="gene ID" value="BV903_24585"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3264"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3217"/>
    <dbReference type="OMA" id="VQITPQI"/>
    <dbReference type="OrthoDB" id="1680841at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="CusB_dom_1"/>
    </dbReference>
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        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
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        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CusB_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="4">
        <location>
            <begin position="64"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="5">
        <location>
            <begin position="137"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="CusB_dom_1" evidence="3">
        <location>
            <begin position="293"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD61253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW26941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="398" mass="42387" checksum="3487B7A9E721BED0" modified="2016-02-17" version="1">MTTEVNPNAAAAAPAAPPKNGKRRKALLILFAVVAIAAVAWTLYYMLVLRWHQDTDDAYVQGNVVNITPQVQGTVVSIGADDGMKVSAGQVLVQLDPNDAQVAYDQSVANLANTVRQVRGLFSAVDAGQADLSAREVAVQKARADVKRREGLVASGAVSAEELAHARDELASAEASLSSSRGSLARNRALVDATTVARQPQVAAAAAQLRQAYLNLQRSAIVAPVNGYVGKRNVQLGQRVAPGTALMTIIPLNEVWVDANFKETQLAKMRIGQPVELHSDLYGSDVRYDGKVVSLGLGTGSAFSLLPAQNASGNWIKIIQRVPVRIEIEPKQLAEHPLRLGLSMHVDVAIRDQNGAVLAAEPPAKPVLSTQAYAKQLHDADAMIDKIVRENLPGVQHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJQ9</accession>
    <name>A0A0S2DJQ9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatidate cytidylyltransferase</fullName>
            <ecNumber evidence="7">2.7.7.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FE772_16660</name>
        <name evidence="9" type="ORF">GLE_3376</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-1,2-diacyl-sn-glycerol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:16229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.7.7.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CDS family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.41" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948250.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3376"/>
    <dbReference type="EnsemblBacteria" id="ALN58722">
        <property type="protein sequence ID" value="ALN58722"/>
        <property type="gene ID" value="GLE_3376"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3376"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3326"/>
    <dbReference type="OMA" id="VPAWCAL"/>
    <dbReference type="OrthoDB" id="1533756at2"/>
    <dbReference type="UniPathway" id="UPA00557">
        <property type="reaction ID" value="UER00614"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016024">
        <property type="term" value="P:CDP-diacylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000374">
        <property type="entry name" value="PC_trans"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01315">
        <property type="entry name" value="CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="28"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="120"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN58722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="284" mass="29924" checksum="F6362AF1A7AFDDF5" modified="2016-02-17" version="1">MTKTRLIAALVMAPVAIAAILLLPTPWLIAAAAVVFLAGLWEWFDLAEIEDTLSRTVLLVVHMALMVALVWASRGGGAGDPGQPPSMVLFKIASLVGVIWWLLALLWLQRFNFASDHRTYARMFKLAAAALSVIPAWCALTWIHAEGGNGHWWLLTALAVVWAADSGAYFAGRKFGMLKLAPRVSPNKTVEGLIGGAVAGVAVGVGLSLLAGATAAQLPWVALVSLVAVLFSVVGDLFESLLKRHVGVKDSGHLIPGHGGVLDRIDGVLAALPAFALGKAIFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJU7</accession>
    <name>A0A0S2DJU7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_17035</name>
        <name evidence="1" type="ORF">GLE_3459</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948308.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58804">
        <property type="protein sequence ID" value="ALN58804"/>
        <property type="gene ID" value="GLE_3459"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3459"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3407"/>
    <dbReference type="OMA" id="HAWGESS"/>
    <dbReference type="OrthoDB" id="2007523at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="97" mass="10633" checksum="4E468F0065087D51" modified="2016-02-17" version="1">MNMHDWVLLKIEIEWSKGELVIGLVDAGSTPVEIKASGMRAFHLERGHAWGESSSLYEAIGPMEVDSGFSRLSLMMQSGDALVVEAESFVLPADIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJU9</accession>
    <name>A0A0S2DJU9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_3526</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948356.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3526"/>
    <dbReference type="EnsemblBacteria" id="ALN58870">
        <property type="protein sequence ID" value="ALN58870"/>
        <property type="gene ID" value="GLE_3526"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3526"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3470"/>
    <dbReference type="OMA" id="WWSESAT"/>
    <dbReference type="OrthoDB" id="1411953at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012430">
        <property type="entry name" value="TMEM43_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07787">
        <property type="entry name" value="TMEM43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594858" evidence="6">
        <location>
            <begin position="28"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="257" mass="27912" checksum="81F1002BBC9F9F7D" modified="2016-02-17" version="1">MNRSAAARALFAFALAASMCAALPAAAQDEDSGEPIGEPVAGKNLRDRDFGVLTRQFGLDRRVEMYQWRRAADPAAGQGGYERIWNSAPIDSSQFAPGHVNPAGLPLENKRWWSESATLDGKPLDSEVLRALGEWSVFRPNFSRLPSNLAATFQPEGDGLGSSENPLAPQIGDLRVTWRELRLPALEGKLELREGAWQLKPEAAAAALNAAPARPSATVLGELPQDRRWSWAWLVAGVAVAGAALVWLRGRRRKRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJY5</accession>
    <name>A0A0S2DJY5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF4870 domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Orotate phosphoribosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_17835</name>
        <name evidence="4" type="ORF">FE772_16760</name>
        <name evidence="2" type="ORF">GLE_3399</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000048">
        <property type="protein sequence ID" value="OPD62535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3399"/>
    <dbReference type="EnsemblBacteria" id="ALN58745">
        <property type="protein sequence ID" value="ALN58745"/>
        <property type="gene ID" value="GLE_3399"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62535">
        <property type="protein sequence ID" value="OPD62535"/>
        <property type="gene ID" value="BV903_17835"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3399"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3348"/>
    <dbReference type="OMA" id="LIVWLMK"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="DUF4870"/>
    </dbReference>
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        <property type="entry name" value="DUF4870"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="115" mass="12479" checksum="D715E8E309DE8746" modified="2016-02-17" version="1">MNDISQDEKTWGMLAHLSTLVGLIVPFGTILGPLVVWLIKKDTMPFVADQGKEALNFNITVLIAMIIGGILTLVLIGVLVMIAVGLAWLVLTIMAALAANKGEAYRYPFTLRLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK16</accession>
    <name>A0A0S2DK16_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribonuclease G</fullName>
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            <ecNumber evidence="7">3.1.4.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">cafA</name>
        <name evidence="8" type="ORF">FE772_16810</name>
        <name evidence="7" type="ORF">GLE_3407</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="3.1.26.-" evidence="8"/>
    <dbReference type="EC" id="3.1.4.-" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW27052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948273.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3407"/>
    <dbReference type="EnsemblBacteria" id="ALN58753">
        <property type="protein sequence ID" value="ALN58753"/>
        <property type="gene ID" value="GLE_3407"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3407"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3357"/>
    <dbReference type="OMA" id="TKGPRIS"/>
    <dbReference type="OrthoDB" id="1209444at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:ribonuclease activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NA-bd_OB-fold"/>
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        <property type="entry name" value="RNA-bd_AU-1/RNase_E/G"/>
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        <property type="entry name" value="RNase_E/G"/>
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        <property type="entry name" value="S1_dom"/>
    </dbReference>
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        <property type="entry name" value="S1_domain"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="39"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW27052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="495" mass="55552" checksum="91229705F7B7C8F5" modified="2016-02-17" version="1">MTEEILVNVTPRETRVAVVENGMLQELHIERGWRRGVVGNIYKGKVQRVMPGMQAAFVEIGLERAAFLHAADIVKPNQSGEGEGDEAPLPPAPTRPIAELLREGQEIIVQVVKDPIGSKGARLTTQLSIPSRYLVLLPRTRVVGVSARIEDEGERARLKSLVTAQAPASEQHGYIVRTNAEGQPEEALAEDIAYLSRAWALIAEKSRSSKIGERVYEDLSLPLRAVRDLIRRDVEKVKVDSRETSERLRSFAAQYMPGLAEKIEHYTGARPIFDLYGVEDEIQRALDKEVPLKSGGYLVIDQTEAMTTIDVNTGSFLGQRNLEETVYRTNLEAAQSVARQLRLRNLGGIIIIDFIDMTDQEHKRQVLRQLEKALTRDHAKTTVYEFSPLGLVEMTRKRTTESLERQLSEACHECGGRGTLKTPETVTYEIFRDIVRQVRQFDAARLLVIASPKVVARITDEESAAVAELEEFLGKSIRFQADDQYAQEQFDVVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK91</accession>
    <name>A0A0S2DK91_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphate-specific transport system accessory protein PhoU</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">phoU</name>
        <name evidence="6" type="ORF">BV903_20470</name>
        <name evidence="7" type="ORF">FE772_16410</name>
        <name evidence="5" type="ORF">GLE_3318</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Plays a role in the regulation of phosphate uptake.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PhoU family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000062">
        <property type="protein sequence ID" value="OPD62059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948204.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000062.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3318"/>
    <dbReference type="EnsemblBacteria" id="ALN58664">
        <property type="protein sequence ID" value="ALN58664"/>
        <property type="gene ID" value="GLE_3318"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62059">
        <property type="protein sequence ID" value="OPD62059"/>
        <property type="gene ID" value="BV903_20470"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3318"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3268"/>
    <dbReference type="OMA" id="WKHGIET"/>
    <dbReference type="OrthoDB" id="1648549at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030643">
        <property type="term" value="P:cellular phosphate ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045936">
        <property type="term" value="P:negative regulation of phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028366">
        <property type="entry name" value="P_transport_PhoU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
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        <property type="entry name" value="PhoU_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42930">
        <property type="entry name" value="PTHR42930"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01895">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003107">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02135">
        <property type="entry name" value="phoU_full"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PhoU" evidence="4">
        <location>
            <begin position="25"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="PhoU" evidence="4">
        <location>
            <begin position="129"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR003107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD62059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW26984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="236" mass="26366" checksum="F3622695EC8EB070" modified="2016-02-17" version="1">MSNQMHDHIVKSYDDEQRRLLDETLRMGEIAAAQLESALDVVQRRDDKAAERIIANDEAIDALEQEISHDVMKLALRGPMARDLREILAAIRIASDIERVGDYAANVAKRSTALNLSPPLPHVAGLHALGTLAVKQLRDVLVAYRDNDVELAQRVRDRDAEVDTAYTGLFRELLTYMMEDARSITACTHLLFMAKNIERVGDHATNIAENVWFLVKGDEPLPPRDKRDATSTTGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKR3</accession>
    <name>A0A0S2DKR3_LYSEN</name>
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            <fullName evidence="4">DUF1456 family protein</fullName>
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    <gene>
        <name evidence="3" type="ORF">BV903_16055</name>
        <name evidence="4" type="ORF">FE772_18985</name>
        <name evidence="2" type="ORF">GLE_3863</name>
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    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
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        </lineage>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000042">
        <property type="protein sequence ID" value="OPD62905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948604.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000042.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3863"/>
    <dbReference type="EnsemblBacteria" id="ALN59206">
        <property type="protein sequence ID" value="ALN59206"/>
        <property type="gene ID" value="GLE_3863"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62905">
        <property type="protein sequence ID" value="OPD62905"/>
        <property type="gene ID" value="BV903_16055"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3863"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3802"/>
    <dbReference type="OMA" id="KEDDMHA"/>
    <dbReference type="OrthoDB" id="1534707at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009921">
        <property type="entry name" value="DUF1456"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07308">
        <property type="entry name" value="DUF1456"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="4"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1456" evidence="1">
        <location>
            <begin position="88"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="157" mass="17873" checksum="2D2559A6C9ACCEBE" modified="2016-02-17" version="1">MIANDVLRSIRYMLDLSDQKVVDLVHLADPAFAIEKADVQAFLKKDEDEGYAPCDDAVLARFLDGLVFHYRGRDESLPPRPLEKRVSNNLVLKKLRVAFELKDLDMHQAFADAGFPVSKPELSALFRQSDHKNFRLCGDQMLRNFLKGLTLRIRGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKY0</accession>
    <name>A0A0S2DKY0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3883</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59226">
        <property type="protein sequence ID" value="ALN59226"/>
        <property type="gene ID" value="GLE_3883"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3883"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3822"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="91" mass="9677" checksum="1D4FD73822CFED26" modified="2016-02-17" version="1">MVGGGAVAAGRWSDGARVAVATAATRRQCERGFPGVNVWIDLNKAKTFKTERAAEIFPGNQRAAFTPAVQGEFDTAHIIPRDCVAPQHGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKY4</accession>
    <name>A0A0S2DKY4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type IV pilus assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pilY1</name>
        <name evidence="3" type="ORF">GLE_3576</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3576"/>
    <dbReference type="EnsemblBacteria" id="ALN58920">
        <property type="protein sequence ID" value="ALN58920"/>
        <property type="gene ID" value="GLE_3576"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3576"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3520"/>
    <dbReference type="OMA" id="ISEMMFE"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008707">
        <property type="entry name" value="PilC_beta_prop_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05567">
        <property type="entry name" value="Neisseria_PilC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Neisseria_PilC" evidence="2">
        <location>
            <begin position="997"/>
            <end position="1335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1445"/>
            <end position="1475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1446"/>
            <end position="1475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1534" mass="162762" checksum="9076F071F790A920" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL06</accession>
    <name>A0A0S2DL06_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Redoxin domain protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">TlpA family protein disulfide reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_18855</name>
        <name evidence="4" type="ORF">GLE_3829</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948584.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3829"/>
    <dbReference type="EnsemblBacteria" id="ALN59172">
        <property type="protein sequence ID" value="ALN59172"/>
        <property type="gene ID" value="GLE_3829"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3829"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3771"/>
    <dbReference type="OMA" id="LRADEPR"/>
    <dbReference type="OrthoDB" id="1617952at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726813" evidence="2">
        <location>
            <begin position="26"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="65"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW27393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="245" mass="25881" checksum="2FB107726FE3FBD5" modified="2016-02-17" version="1">MISTARTRRALPLLAVAIAATLLGACQKSDDPRSIDRTDEIKRADAERIAAQAAAPAPADKPAEAPAASDVPELRIATLDGKTYDLAEHRGKWVVVNFWATWCAPCIKEMPELSALDAMREHIEVIGLAYEEIDKADMQAFLKQHPVSYPIAVLDVTDPPKSFDTPKGLPMTYLIGPDGKVVEKFLGPVDAKKLEDAIAKAGGPKPGEPAGQGGAGKNGSNEDDSSKDDSSKDDSSKGGPSGGHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL61</accession>
    <name>A0A0S2DL61_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chemotaxis protein CheX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_19380</name>
        <name evidence="3" type="ORF">GLE_3950</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948670.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3950"/>
    <dbReference type="EnsemblBacteria" id="ALN59292">
        <property type="protein sequence ID" value="ALN59292"/>
        <property type="gene ID" value="GLE_3950"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3950"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3887"/>
    <dbReference type="OMA" id="IIPILWE"/>
    <dbReference type="OrthoDB" id="1956590at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028976">
        <property type="entry name" value="CheC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028051">
        <property type="entry name" value="CheX-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13690">
        <property type="entry name" value="CheX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103039">
        <property type="entry name" value="SSF103039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheX" evidence="2">
        <location>
            <begin position="48"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="153" mass="16537" checksum="D473803D47534362" modified="2016-02-17" version="1">MSDLNETEIKVFIDAVTNYFNQLTQEPANVRGAFLDDNGGTAPVFDYSGQIAVSGQFRGTITVSAPRAMIRHLLLALNESDQSDANLRDTIGELANTLAGNARKHFGGEMEISVPRTAAGAIGGSGSRKRPYVIMVSWKTYSASLVVDIERLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL97</accession>
    <name>A0A0S2DL97_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_19595</name>
        <name evidence="1" type="ORF">GLE_3998</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948702.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59340">
        <property type="protein sequence ID" value="ALN59340"/>
        <property type="gene ID" value="GLE_3998"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3998"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3934"/>
    <dbReference type="OrthoDB" id="1992345at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="154" mass="17085" checksum="596A566616536136" modified="2016-02-17" version="1">MLECTPHSVFSWNYSVSGLQLGTAELTFEALSDRGAIAIDGVRFDIRKQGWLDASWTLERDGNTVAIAKRRGMLGRSFDLTHAGAVLLLKPQTLLVRDYHLLLADTVVGTIEPEHPLTRKARVQCDATVAEIVQLFSFWLVAMIWRSTTDASPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLE5</accession>
    <name>A0A0S2DLE5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_4032</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4032"/>
    <dbReference type="EnsemblBacteria" id="ALN59374">
        <property type="protein sequence ID" value="ALN59374"/>
        <property type="gene ID" value="GLE_4032"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4032"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3974"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="5">
        <location>
            <begin position="119"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="325"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="543" mass="58962" checksum="62B4A99B84D55F60" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLM4</accession>
    <name>A0A0S2DLM4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Cobyric acid synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">cobQ</name>
        <name evidence="11" type="ORF">FE772_20045</name>
        <name evidence="10" type="ORF">GLE_4085</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CobB/CobQ family. CobQ subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948770.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4085"/>
    <dbReference type="EnsemblBacteria" id="ALN59427">
        <property type="protein sequence ID" value="ALN59427"/>
        <property type="gene ID" value="GLE_4085"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4085"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4027"/>
    <dbReference type="OMA" id="EIHHGVA"/>
    <dbReference type="OrthoDB" id="744477at2"/>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015420">
        <property type="term" value="F:ABC-type vitamin B12 transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01750">
        <property type="entry name" value="GATase1_CobQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00028">
        <property type="entry name" value="CobQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033949">
        <property type="entry name" value="CobQ_GATase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004459">
        <property type="entry name" value="CobQ_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011698">
        <property type="entry name" value="GATase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21343:SF1">
        <property type="entry name" value="PTHR21343:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07685">
        <property type="entry name" value="GATase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00313">
        <property type="entry name" value="cobQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="10" id="KW-0436">Ligase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiA" evidence="8">
        <location>
            <begin position="11"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="GATase_3" evidence="9">
        <location>
            <begin position="257"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="336"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW27591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="506" mass="53718" checksum="B22AB469F63918D0" modified="2016-02-17" version="1">MSESCGPARVLMVQGCTSDAGKSALVAALCRWLRRRGVAVAPFKPQNMALNSAVTADGGEIGRAQAVQAQAAGLAPHTDFNPILLKPSSDTGAQVIVHGRAVAQLDARAYHDYKRVAMDAVLASHARLCERYAAVVVEGAGSPAEINLRDRDIANMGYAEAVDCPVILIADIDRGGVFAHLVGTLALLSDSERARVAGFVINRFRGDIGLLQSGLDWLERETGKPVLGVLPYLHGLHLEAEDALPRAADAKAGARLRVAVPALPRISNHTDFDALRAHPQVDCRFVGPGDAPPPCDLIVLPGSKATRADLAWLRRNGWAEAIARHLRYGGRVIGICGGLQMLGRTVHDPHGIEGEAGSSEGLGWLDLDTTLQPYKQLRNAKGRLSFADAVAEGYEIHCGVSAGAGLQRPALRLDDGRDDGAISADGQVLGTYLHGVFDHPQALAALLGWAGLEQAEPLDLRGLREHSIDRLADAVERHLDTAALARLFGLGADRDTQPREESACAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLP7</accession>
    <name>A0A0S2DLP7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Probable lipid kinase YegS-like</fullName>
            <ecNumber evidence="11">2.7.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BV903_04600</name>
        <name evidence="13" type="ORF">GLE_4286</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">C3</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">B25</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Probably phosphorylates lipids; the in vivo substrate is unknown.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="11">Binds 1 Mg(2+) ion per subunit. Ca(2+) may be able to substitute.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="11"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000008">
        <property type="protein sequence ID" value="OPD65203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948934.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000008.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4286"/>
    <dbReference type="EnsemblBacteria" id="ALN59627">
        <property type="protein sequence ID" value="ALN59627"/>
        <property type="gene ID" value="GLE_4286"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65203">
        <property type="protein sequence ID" value="OPD65203"/>
        <property type="gene ID" value="BV903_04600"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4286"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4225"/>
    <dbReference type="OMA" id="GFDSRVN"/>
    <dbReference type="OrthoDB" id="869726at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001727">
        <property type="term" value="F:lipid kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01377">
        <property type="entry name" value="YegS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005218">
        <property type="entry name" value="Diacylglycerol/lipid_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022433">
        <property type="entry name" value="Lip_kinase_YegS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045540">
        <property type="entry name" value="YegS/DAGK_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19279">
        <property type="entry name" value="YegS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03702">
        <property type="entry name" value="lip_kinase_YegS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00147">
        <property type="entry name" value="TIGR00147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 11 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 11" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8 11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="10 11" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="12">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="65"/>
            <end position="71"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN59627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OPD65203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="326" mass="34027" checksum="4ABEAE1F8E842B5F" modified="2016-02-17" version="1">MTSPRWRLILNGKSAGNDDVRKAVAALRDRGVALDVRVTWEGGDAERYVAEAIADGVDTVIAGGGDGTLSEVATTLAHRDEDADALPSLGLLPLGTANDFASAATIPTDPAQALDLVQRCPPRPVDLLRLQAPDGLHWAANLASGGFGTQVTLETDAGLKKMLGGLAYVVTGIAKLGRIEPMRARVHGEGFEWEGDFIALGIGNGRQAGGGQALCPDARIDDGLLDVTVVPDLSGEVGATVRALLTEGQHAALERIAARAQLRWVEIESPQPLNLNLDGEPVQSRHFRIDCAPGRVRMHLPPGCPLLSEPAAAETLPGAAAHATAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLV0</accession>
    <name>A0A0S2DLV0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">D-lactate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4146"/>
    <dbReference type="EnsemblBacteria" id="ALN59488">
        <property type="protein sequence ID" value="ALN59488"/>
        <property type="gene ID" value="GLE_4146"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4146"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4088"/>
    <dbReference type="OMA" id="RACNAYS"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-linked_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="1">
        <location>
            <begin position="40"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="464" mass="48362" checksum="71F3BC2B62D85329" modified="2016-02-17" version="1">MNAGAPLPPALHAELAPLLGEAWLTDPGERLAYAYDNSRRLALPDAVALPRTREQVQALVRACRRERVPVIARGRGTNTTGASVPVAGGVVVSFERMNRIVDIRPGDRCAVVEPGVLNGDLQTALKPHGLFWPPDPTSAAYSSVGGNLACNAGGPRAVKYGASRDNVLALTAITGAGELIVCGTATTKGSTGYDLHRLLVGSEGTLALIVEASLRLTPSAPARAALRAVYRDVSSAAQAVARLMAQPVTPSMLEFMDGQCVRLARDVGGADLPLDAGALLMIEADGDAHTLPHAIDALKRAAAGDGLLSLDDAADEAARETLWAARKALSPSLRTLAPGKINEDVVVPVSRIPELVDGVQALAREFDLPIVCFGHAGNGNLHVNLLFDPADADQSARAHAAMGRVFELALALGGTLSGEHGIGLAKRDFMPQAVGAQTLALMRQLKTVFDPDAILNPGKLLPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMD7</accession>
    <name>A0A0S2DMD7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ferredoxin reductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_21455</name>
        <name evidence="7" type="ORF">GLE_4392</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949015.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4392"/>
    <dbReference type="EnsemblBacteria" id="ALN59733">
        <property type="protein sequence ID" value="ALN59733"/>
        <property type="gene ID" value="GLE_4392"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4392"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4331"/>
    <dbReference type="OMA" id="YVRIGVD"/>
    <dbReference type="OrthoDB" id="1885467at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="6">
        <location>
            <begin position="42"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="5">
        <location>
            <begin position="286"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW27829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="368" mass="39797" checksum="F406D276BAB3D78C" modified="2016-02-17" version="1">MNAAVRPAAARPRSRLRRLVSPFVSPQVFDFWASRFHPTWSWERPLARIVGRSEASADAATLLLAPNRHWRGAVAGQHLLIGARIDGVLVTRSYSLSAAPRADGRIEITVKAIEGGKLSGYLHQRARIGEVLELGAAFGEMVLPQRDDGARLFLAAGSGVTPLMAMVRAQAERAMPQPLTLLYWARRREELCFVEELRALAAAHANFQVRFLLTRQEPQAADEDAGRIDADLLARHARDLRERAVFACGPGGFVESARALADGAARSFASEAFTPPPRETREDGHAQVVLARSGRTFELPRGESLLTALEAQGLKLPSGCRMGLCNTCACGKSSGATRHLHTGELHAEPASALRLCVSAPAGDLVLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMG4</accession>
    <name>A0A0S2DMG4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4276</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59617">
        <property type="protein sequence ID" value="ALN59617"/>
        <property type="gene ID" value="GLE_4276"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4276"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4214"/>
    <dbReference type="OMA" id="IAKKMWH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014942">
        <property type="entry name" value="AbiEii"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08843">
        <property type="entry name" value="AbiEii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="181" mass="20581" checksum="004B9093CFB292CE" modified="2016-02-17" version="1">MLMLRIDHRQSRDIDLFVPDPQYLGYVSPRLNDVAESISADYEQAAEYLKLFLPGGEVDVVVGTPLTEQPFDLVEYRGRTIKVETSGEIVAKKMWHRGDRAKARDLFDLCAVDRAEPEQIEAAKPWMARHGAAFLDGLSLRETLLRREFEEIDAIGPRMSFEECFSQAERIIRPVLRGTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMM7</accession>
    <name>A0A0S2DMM7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Anthranilate phosphoribosyltransferase</fullName>
            <ecNumber evidence="5">2.4.2.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">trpD</name>
        <name evidence="9" type="ORF">BV903_04565</name>
        <name evidence="10" type="ORF">FE772_20915</name>
        <name evidence="8" type="ORF">GLE_4272</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>diphosphate + N-(5-phospho-beta-D-ribosyl)anthranilate = 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate</text>
            <dbReference type="Rhea" id="RHEA:11768"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:18277"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5">Binds 2 magnesium ions per monomer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the anthranilate phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.18" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000008">
        <property type="protein sequence ID" value="OPD65196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948920.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000008.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4272"/>
    <dbReference type="EnsemblBacteria" id="ALN59613">
        <property type="protein sequence ID" value="ALN59613"/>
        <property type="gene ID" value="GLE_4272"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65196">
        <property type="protein sequence ID" value="OPD65196"/>
        <property type="gene ID" value="BV903_04565"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4272"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4210"/>
    <dbReference type="OMA" id="GPMTNPA"/>
    <dbReference type="OrthoDB" id="1238435at2"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00041"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004048">
        <property type="term" value="F:anthranilate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00211">
        <property type="entry name" value="TrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005940">
        <property type="entry name" value="Anthranilate_Pribosyl_Tfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000312">
        <property type="entry name" value="Glycosyl_Trfase_fam3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017459">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036320">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43285">
        <property type="entry name" value="PTHR43285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02885">
        <property type="entry name" value="Glycos_trans_3N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47648">
        <property type="entry name" value="SSF47648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="SSF52418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01245">
        <property type="entry name" value="trpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 5" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="1 5 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 5" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Glycos_trans_3N" evidence="7">
        <location>
            <begin position="5"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_3" evidence="6">
        <location>
            <begin position="75"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosylpyrophosphate binding" evidence="5">
        <location>
            <begin position="85"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosylpyrophosphate binding" evidence="5">
        <location>
            <begin position="92"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosylpyrophosphate binding" evidence="5">
        <location>
            <begin position="110"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>anthranilate</name>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>anthranilate</name>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD65196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="342" mass="36347" checksum="5116F00274501BA0" modified="2016-02-17" version="1">MTPQEALQRTIEHREIFHDEMVALMRTIMRGEVSPTMTAAILTGLRVKKETVGEIAGAATVLREFARPVPVADRSHLVDIVGTGGDGAHTFNISTASMFVVAAAGAKVAKHGNRSVSSKSGSADVLEALGAAIELQPEQVAQCIERAGIGFMFAPVHHPAMKVVAPVRREMGVRTLFNILGPLTNPADAPSILMGVFHPDLVGIQVRVLEELGAKRALVVWGRDGMDELSLGAGTLVGELRDGQVREYEVHPEDFGIAMAASRNLRVEDAVESKAMVLQALENRDGLPREIVALNSGAALYVSGKVESIAEGIELARRTLASGAARAKLDEFVALTAQLAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMU8</accession>
    <name>A0A0S2DMU8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Patatin-like phospholipase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BV903_03635</name>
        <name evidence="6" type="ORF">FE772_22170</name>
        <name evidence="4" type="ORF">GLE_4541</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">C3</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">YC36</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000006">
        <property type="protein sequence ID" value="OPD65388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949133.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4541"/>
    <dbReference type="EnsemblBacteria" id="ALN59882">
        <property type="protein sequence ID" value="ALN59882"/>
        <property type="gene ID" value="GLE_4541"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65388">
        <property type="protein sequence ID" value="OPD65388"/>
        <property type="gene ID" value="BV903_03635"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4541"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4477"/>
    <dbReference type="OMA" id="CSMPGLL"/>
    <dbReference type="OrthoDB" id="373926at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="23"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="54"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="170"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD65388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW27948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="322" mass="35078" checksum="E58171E4BBFBC09A" modified="2016-02-17" version="1">MAGADIPRAGQTGLAEQGEPVALVLGAGGARGLAQIGVIEALQARGLRIVAVAGSSSGALVGGLFAAGKMGVYRDWLYSMSRTDMLRLLDPVFGQPALFRGDRLMHALRELIGEPRIEELPVQFTAVAVDLLRQREVWLREGDLWDAIRASIAIPGVFTPYELHGRELVDGGLLAPLPITATRLSDAHRLIAVDMHGWPDQPTGALGRHAGADEARHAPVPASQIVSVKPPPLTRWFRRNQPVTVDPPEDAPPHELSFSELMARSLDTMQAQIARVQLALDPPELVIRIPRDACQFYEFWRAKELIELGREQAEQALDKAGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN50</accession>
    <name>A0A0S2DN50_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_22760</name>
        <name evidence="3" type="ORF">GLE_4673</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4673"/>
    <dbReference type="EnsemblBacteria" id="ALN60014">
        <property type="protein sequence ID" value="ALN60014"/>
        <property type="gene ID" value="GLE_4673"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4673"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4609"/>
    <dbReference type="OMA" id="QYTIAPV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242248" evidence="1">
        <location>
            <begin position="25"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="2">
        <location>
            <begin position="35"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="338" mass="37593" checksum="AB8986D69A5D7BBA" modified="2016-02-17" version="1">MRPSARLRCLLACLLMIAAAAAAAASKPQAPPPDRRIALTVDDLPWVQLPVVSTESILDGHRRLIAAIRRADVPVVGFVNEGKLDADGQPQPARLAMLRDWLDAGAELGNHTYGHSDLHAVGLAAYQDDILRGERQLRPLLQARGQAPRWFRHPYLRAGRSAADKAALARFLDQHGYRIAPVTVDNSDWIWAAAYLRADEPLPAGAKPSAKNDPQRLKARLRRDYVKYMGRKLDYYERQSVALLGYNLPQVWLIHANALNADSYGDLIAMARKRGYRFIGLDEAMRDPAYQRADAYTGPAGPSWLHRWAIGEKRPASFFAGEPSVPDWVLNLAQIDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNA3</accession>
    <name>A0A0S2DNA3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">TonB family domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLE_4556</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TonB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4556"/>
    <dbReference type="EnsemblBacteria" id="ALN59897">
        <property type="protein sequence ID" value="ALN59897"/>
        <property type="gene ID" value="GLE_4556"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4556"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4492"/>
    <dbReference type="OrthoDB" id="2074833at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="TonB_C" evidence="10">
        <location>
            <begin position="290"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="55"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="228"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="381"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN59897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="428" mass="42869" checksum="B53E136C75EDA799" modified="2016-02-17" version="1">MIEPARIVAAGQGPGARRRNGAWGWQDAAAGVALGLGLAILSGCGSGQPAASESAAAAPASAQDAADRAAPLPPALDELDAGGLRDRAARALREQRIHTPAGDSAVDYYLALREKAPGHADVAAALTELQPYVVIAGEQALADGDLAESRRLTDLLARMDPQAPALPRLREGLRSAQGEHERRAREDAERLAGERAEAATLARTQAAQRTAAANAALKAQANASAAAADEAAARASTPPAPVPHPAAAHPTGASAAAASAAPAPAAAAAATPAVPKPAAKIAPRLIADASPRYPSVAITRKLEGSVEVAFTIQPDGSTGAARVLSSQPAGVFDEAALSAVARLRSKAQRPEPSGPAHLELQAAAALSAGRAQRLAADRAIGRRTGGGPDHEPPAAPARAGPAPARRFGAAVGAVGASGHNAAHEQRHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNE8</accession>
    <name>A0A0S2DNE8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4719</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60060">
        <property type="protein sequence ID" value="ALN60060"/>
        <property type="gene ID" value="GLE_4719"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4719"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4653"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="49" mass="5398" checksum="F308465DC55133F1" modified="2016-02-17" version="1">MGFVLACACARRQANIKSFRPQAAGSLSLSEATKKVTKEKALFFRIKSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNF9</accession>
    <name>A0A0S2DNF9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">S-(hydroxymethyl)glutathione dehydrogenase</fullName>
            <ecNumber evidence="5 8">1.1.1.284</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLE_4842</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>NAD(+) + S-(hydroxymethyl)glutathione = H(+) + NADH + S-formylglutathione</text>
            <dbReference type="Rhea" id="RHEA:19985"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58758"/>
            <dbReference type="EC" id="1.1.1.284"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>NADP(+) + S-(hydroxymethyl)glutathione = H(+) + NADPH + S-formylglutathione</text>
            <dbReference type="Rhea" id="RHEA:19981"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57688"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58758"/>
            <dbReference type="EC" id="1.1.1.284"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.284" evidence="5 8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4842"/>
    <dbReference type="EnsemblBacteria" id="ALN60183">
        <property type="protein sequence ID" value="ALN60183"/>
        <property type="gene ID" value="GLE_4842"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4842"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4772"/>
    <dbReference type="OMA" id="IHHYMGT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106322">
        <property type="term" value="F:S-(hydroxymethyl)glutathione dehydrogenase NAD activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106321">
        <property type="term" value="F:S-(hydroxymethyl)glutathione dehydrogenase NADP activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006069">
        <property type="term" value="P:ethanol oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08300">
        <property type="entry name" value="alcohol_DH_class_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014183">
        <property type="entry name" value="ADH_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02818">
        <property type="entry name" value="adh_III_F_hyde"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="7 8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="9">
        <location>
            <begin position="16"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN60183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="373" mass="39440" checksum="1DFB01FEAC555DE1" modified="2016-02-17" version="1">MSRVIKSRAAVAFAAGEPLKIVEIDVQPPKAGEVLVRIHATGVCHTDAFTLSGDDPEGLFPAVLGHEGGGVVVEVGEGVTSLKPGDHVIPLYTAECRECKFCLSGKTNLCQAVRATQGKGLMPDGTSRFSYEGQPIHHYMGCSTFSEYTVVPEISLAVVNPEAPLEKVCLLGCGVTTGIGAVHNTAKVQPGDTVAVFGLGGIGLAVIQGAVQAKAGRIIGVDTNASKFELAKKMGATDCVNPKDSERPIQDVLVEMTDGGVDFSFECIGNVEVMRSALECCHKGWGESVIIGVAGAGQEIKTRPFQLVTGRVWRGTAFGGVKGRTQLPGMVEQAMSGEIDLDPFITHTLPLERINEAFDLMHEGKSIRTVIHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNK7</accession>
    <name>A0A0S2DNK7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4678</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60019">
        <property type="protein sequence ID" value="ALN60019"/>
        <property type="gene ID" value="GLE_4678"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4678"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4614"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="39" mass="4274" checksum="C194E706A8FD1B41" modified="2016-02-17" version="1">MWAAATESVCRNGAVDRVGDANGDKRESRVPSRERGGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNM9</accession>
    <name>A0A0S2DNM9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fmn-dependent NADH-azoreductase 2</fullName>
            <ecNumber evidence="3">1.7.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">azoR</name>
        <name evidence="3" type="ORF">GLE_4905</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.7.-.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4905"/>
    <dbReference type="EnsemblBacteria" id="ALN60246">
        <property type="protein sequence ID" value="ALN60246"/>
        <property type="gene ID" value="GLE_4905"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4905"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4836"/>
    <dbReference type="OMA" id="WIHAAFT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003680">
        <property type="entry name" value="Flavodoxin_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02525">
        <property type="entry name" value="Flavodoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin_2" evidence="2">
        <location>
            <begin position="3"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="167"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="198" mass="22328" checksum="6DA26FA32CBDDB29" modified="2016-02-17" version="1">MRRWRELRPGDDVIVRDVGLHPPAPVTGGWIHAAFTPPAQREPWMREALAESDALVEELLAADLVVVGVPMYNFGMPAQLKAWIDNVVRVGRTFGFDRTREGEPYWPMLADQGRQLVLLSSRGDYGYGRGERLEAINHVEPGVLTPLRYIGIDDAHSVAVEYDEFGDERLRASIERAERDIDALVQRLTAERVLREAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNZ9</accession>
    <name>A0A0S2DNZ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_10440</name>
        <name evidence="3" type="ORF">FE772_23410</name>
        <name evidence="1" type="ORF">GLE_4819</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000023">
        <property type="protein sequence ID" value="OPD63999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949335.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4819"/>
    <dbReference type="EnsemblBacteria" id="ALN60160">
        <property type="protein sequence ID" value="ALN60160"/>
        <property type="gene ID" value="GLE_4819"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63999">
        <property type="protein sequence ID" value="OPD63999"/>
        <property type="gene ID" value="BV903_10440"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4819"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4750"/>
    <dbReference type="OMA" id="DAVEPQW"/>
    <dbReference type="OrthoDB" id="1762786at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD63999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="114" mass="12404" checksum="C0C0295B7910037B" modified="2016-02-17" version="1">MATRYFLSIPDADRARGSDADLSFTAISSEGFAAQLQDALRSDALFERWRAKQPDPDEVDPSLGATDPNATVVGEQRDLRMDLTVVTALSGTVLKHRLRLLAGSGWELRDVTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP26</accession>
    <name>A0A0S2DP26_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4993</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60334">
        <property type="protein sequence ID" value="ALN60334"/>
        <property type="gene ID" value="GLE_4993"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4993"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4921"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="109" mass="12368" checksum="63543DC7ECDADD6F" modified="2016-02-17" version="1">MPYMDNLTGLYQKLSKTDNPHPIHFAIEQKVEFEAAISKIDSTRHDLLHFNSKSWSIGKNYLREEALLACKIIAALCAPTSTIVWHDEEGSVRMQLAVTKLNKALRDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPC6</accession>
    <name>A0A0S2DPC6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Integral membrane protein DUF6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4818</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949334.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60159">
        <property type="protein sequence ID" value="ALN60159"/>
        <property type="gene ID" value="GLE_4818"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4818"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4749"/>
    <dbReference type="OMA" id="VIALQSW"/>
    <dbReference type="OrthoDB" id="1515911at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="13"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="166"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="324" mass="32835" checksum="0D780F925C3F51CD" modified="2016-02-17" version="1">MITATRAGAPLAAIALALAAGTLWGSLGLITRALLGYGLGAAQLALLRLGGAFAITLLAALALRRVRALSMRQWAWLAAIGAVCQALGSVSFSAAVDGAGSSLAIVLLCMGPLFTAAIDRLCFGERLDGAAWRLVLLALSGLALSVLCGRGEPAAAGLFAAPWYAGVAWGLLSGLCYGLFPIFARALGPLDTWVVVSFSLGLGAACLAPLHGAAPAAWPALSDVPAWLWIAALILIPTVFADVLYVRAIALGGPMLATVFALVEVPAAALYARWWLGAPIAPAQWFGIALFCSGLAGLAWCRGTAAAAPAAAADLPAVQPETPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPJ4</accession>
    <name>A0A0S2DPJ4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Peptidase S8</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Peptidase, families S8 and S53</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FE772_24890</name>
        <name evidence="9" type="ORF">GLE_5135</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949581.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5135"/>
    <dbReference type="EnsemblBacteria" id="ALN60476">
        <property type="protein sequence ID" value="ALN60476"/>
        <property type="gene ID" value="GLE_5135"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5135"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5060"/>
    <dbReference type="OMA" id="WTTAGQC"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07496">
        <property type="entry name" value="Peptidases_S8_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034176">
        <property type="entry name" value="Peptidases_S8_13"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726690" evidence="7">
        <location>
            <begin position="29"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="8">
        <location>
            <begin position="159"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="197"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="440"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="440"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN60476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW28407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="465" mass="47077" checksum="75BE7A466307AFE2" modified="2016-02-17" version="1">MSTQSTLRLRRHVLAAAVLGVIAAPAFASDRVDLSGLKADEPVDGFLVTYDAGAPKAAAFQRDLDIALASVGRKDLKIRHTRTISTGAELVEVNRTLDVVEAAALMKSIAADPRVKFVEPNARFYPTFTPNDTNYPSQWGLHGTWGIKANTAWDNTYQGQGKIIAVIDTGITDHPDLVGNLTSPLGYDFISNAATANDGGGRDADPHDPGDWTSAGQCGLGQPARNSSWHGTHVSGIAAGVTNNAAGIAGTAFKAKILSARVLGRCGGTLADIADAITWASGGTVSGVPSVGANKATVINMSLGGGGACSSTSAMQVAITNAYNAGTTVVVAAGNSNAPASGFQPASCANVINVGATTSAGVRASFSNHGSLVDVAAPGQSILSTLNAGTTTPGAFNYVNYNGTSMAAPFVAGIVALMQSKPSPDLSPAQVEQIIKSTASPFATPQSPTIGTGIANADAATDATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPP2</accession>
    <name>A0A0S2DPP2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Relaxation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_07915</name>
        <name evidence="6" type="ORF">D9T17_03785</name>
        <name evidence="5" type="ORF">FE772_25105</name>
        <name evidence="3" type="ORF">GLE_5183</name>
    </gene>
    <organism evidence="3 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">C3</strain>
        </source>
    </reference>
    <reference evidence="4 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">OH11</strain>
        </source>
    </reference>
    <reference evidence="5 10" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 10">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000016">
        <property type="protein sequence ID" value="OPD64464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000011">
        <property type="protein sequence ID" value="ROU08605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949615.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000011.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60524">
        <property type="protein sequence ID" value="ALN60524"/>
        <property type="gene ID" value="GLE_5183"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64464">
        <property type="protein sequence ID" value="OPD64464"/>
        <property type="gene ID" value="BV903_07915"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5183"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5103"/>
    <dbReference type="OMA" id="QFERRCE"/>
    <dbReference type="OrthoDB" id="1696912at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="111"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="10"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD64464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW28442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROU08605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="189" mass="21116" checksum="88D61138B0DF1CBF" modified="2016-02-17" version="1">MQQDELMALISKTAVLMEQFERRCEELERHQRTVAEHLQALAQQVPGVLRQSADDSLRTLPGAVMGKLESGLSEPVGAYEKRLKDAGTLLHAGSQTLAGQLKRMEELHKHLVWKVVGAAFGSVLLLLLGGGWLLWQYRADIDHNRISAELLRAYNQADVTLCDGRLCANVDEKGKAYGDQKQYRPIQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPQ0</accession>
    <name>A0A0S2DPQ0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">YceI like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_5181</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5181"/>
    <dbReference type="EnsemblBacteria" id="ALN60522">
        <property type="protein sequence ID" value="ALN60522"/>
        <property type="gene ID" value="GLE_5181"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5181"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5101"/>
    <dbReference type="OMA" id="RYTGWMR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007372">
        <property type="entry name" value="Lipid/polyisoprenoid-bd_YceI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036761">
        <property type="entry name" value="TTHA0802/YceI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04264">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00867">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101874">
        <property type="entry name" value="SSF101874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595077" evidence="2">
        <location>
            <begin position="35"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="YceI" evidence="3">
        <location>
            <begin position="53"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="239" mass="26342" checksum="345FBA955DE06CE1" modified="2016-02-17" version="1">MSPARPLRPRQRLRGRGAAWAWLLALAGSAGAQASLPPVPPAAPAPGPRVVRQQGFDPLHTRFSFELRTRWGQKVEGEFPRYDGEVNVLADGRHQVRIRLATGEVVVGGSERYTRMARSDRFFAAQRYPYIEFLSEPHPADLARTGGALRGRLTLHGISRMETFVLGPAACARPGEDCDAIAHGSVSRDDYALDGWQFALGNRVRFTMQVRLESTQNKPLSPRPPSPRPPPSAPVPPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQC1</accession>
    <name>A0A0S2DQC1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_00105</name>
        <name evidence="2" type="ORF">GLE_5363</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949749.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60704">
        <property type="protein sequence ID" value="ALN60704"/>
        <property type="gene ID" value="GLE_5363"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5363"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5278"/>
    <dbReference type="OrthoDB" id="1951289at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242474" evidence="1">
        <location>
            <begin position="23"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="155" mass="16277" checksum="ED7D711AB5181BB1" modified="2016-02-17" version="1">MRTFFAAACALVLAGSGAAAHAQQTTFPAPKFRGGNTDWQVVLSTRQTDLSVVYRLRVPQAADPLSSGLRHGAAAAGGYELIGTIGVEKTSVTVKIAPVPLGGVCKIDNGLMGDAYGRFAYSIDVIPEKSKPLSTKADHKPWPAKWSGCGNFTLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQM9</accession>
    <name>A0A0S2DQM9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoadenosine phosphosulfate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5487</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5487"/>
    <dbReference type="EnsemblBacteria" id="ALN60828">
        <property type="protein sequence ID" value="ALN60828"/>
        <property type="gene ID" value="GLE_5487"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5487"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5402"/>
    <dbReference type="OMA" id="LPETYEY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAPS_reduct" evidence="1">
        <location>
            <begin position="6"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="244" mass="28258" checksum="4AEE7B5AF25F637F" modified="2016-02-17" version="1">MRDRVPNMEYIFNDTGKELPETYEYLDRIGDYLGRPVMRLNADKGFDHWYQLYGGMIPSNHRRWCTKMLKLKPFEAYVGDAPVVNYVGIRADEDRQGYISTKPNITPVYPFIEDGLVYADIVRILNQSGVGMPPYTRWGRTRSGCFFCFYQQKIEWVNLLETYPDLFDEAAEYEKEYAPTGNLFTWSNGERLDDLRRPERVAQIKAEAAVRSARGPAKENRSLADVFRAEREVTVDDGCIVCSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQP5</accession>
    <name>A0A0S2DQP5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">H-NS histone family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Virulence regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_00670</name>
        <name evidence="2" type="ORF">GLE_5491</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949844.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60832">
        <property type="protein sequence ID" value="ALN60832"/>
        <property type="gene ID" value="GLE_5491"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5491"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5406"/>
    <dbReference type="OMA" id="APKYWLP"/>
    <dbReference type="OrthoDB" id="1656269at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001801">
        <property type="entry name" value="Histone_HNS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00816">
        <property type="entry name" value="Histone_HNS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="167" mass="17773" checksum="3CAE7AD399F1385F" modified="2016-02-17" version="1">MALTTLQSIDAEIKQLEAQKKLVEKRDSEVPKAIEVLQRYAKVLTPAQRRKLAKISGSGLDADAKAPARASRARKIGKVAPKYRLPTGETWTGRGRTPIAFVAWETGAEGKAWRKTNKGGRFPAIDGASAKTPTSAVSTKASRGAAKKIGKKAAKKAARPAKKAAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA30</accession>
    <name>A0A0S2DA30_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_01160</name>
        <name evidence="1" type="ORF">GLE_0047</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945754.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0047"/>
    <dbReference type="EnsemblBacteria" id="ALN55406">
        <property type="protein sequence ID" value="ALN55406"/>
        <property type="gene ID" value="GLE_0047"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0047"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.54"/>
    <dbReference type="OMA" id="HINDQTW"/>
    <dbReference type="OrthoDB" id="1869306at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="180" mass="20054" checksum="BD41362BBC11B6DA" modified="2016-02-17" version="1">MPTYDKNPTPKQRYDVTVVIENAPGPFAVVHGAVQYDIANMDCLPPAESFSGAQTTPISTFVPIVLKRVNDTTFEGQFALDELVDGDYFGRGICHFKPIGPSFSLKASQAAGDTKFVASRWANELEQADQLTTYYWRASYPRHAKIEDYSDLGSSSPDEYKESVRSELFSVSVRTRKVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAD1</accession>
    <name>A0A0S2DAD1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF2163 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_01105</name>
        <name evidence="3" type="ORF">GLE_0034</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945745.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0034"/>
    <dbReference type="EnsemblBacteria" id="ALN55393">
        <property type="protein sequence ID" value="ALN55393"/>
        <property type="gene ID" value="GLE_0034"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0034"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.41"/>
    <dbReference type="OMA" id="AYPGCAR"/>
    <dbReference type="OrthoDB" id="756610at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011928">
        <property type="entry name" value="Phage_phiJL001_Gp84"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018964">
        <property type="entry name" value="Phage_phiJL001_Gp84_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019228">
        <property type="entry name" value="Phage_phiJL001_Gp84_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09931">
        <property type="entry name" value="DUF2163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09356">
        <property type="entry name" value="Phage_BR0599"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02218">
        <property type="entry name" value="phg_TIGR02218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2163" evidence="2">
        <location>
            <begin position="17"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Phage_BR0599" evidence="1">
        <location>
            <begin position="186"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="271" mass="29278" checksum="757A3D8A4166F785" modified="2016-02-17" version="1">MSFDQYERSTAAGNPRRLYEFVRGGQRWRYTGGDRDFQLDTQTFRAVAISDDGIRQSGHVASDVLTITAPGDFDVARLYRGLPPSTEVAVVVRDIHEGDTEARVSWVGRIAGVNRPRLETSEVRCQSLDAALGQPGLRLAWTRGCPHTLYDRNCRVNPEAHRLPALLATVAGNVVTAGAFGLHPDGWLAGGFLAWDLGEAGIERRGIRFHEGERLILLGAGDGLRVGQAVVAYPGCARTIAICHSKFANAPNYGGVPGLPGKSPFDGTPVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAH1</accession>
    <name>A0A0S2DAH1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PKD repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0166</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945842.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0166"/>
    <dbReference type="EnsemblBacteria" id="ALN55525">
        <property type="protein sequence ID" value="ALN55525"/>
        <property type="gene ID" value="GLE_0166"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0166"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.168"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594785" evidence="1">
        <location>
            <begin position="27"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="412" mass="43486" checksum="64636C64D2F853EC" modified="2016-02-17" version="1">MKLSNATPRALAVALLGWMLATPALAADATPGPSLAGQSRAIDLRLGAQSGLSKSAWSAPVKIHAADAAYIKVHFAQFDLPAGVVLEVSDPKRSEVYRYRKGDLGRYTVDAALGEDGKTRFGAMSVAGDTAVLRLTGTPTEPWAPHHGVRVARYDEGFPQAMMGELSDAGLLNGGGSAKSICGTKDSRPVACYASTDATAVARSKPVALILLNGTKWCTAWRVGPDNRIFTNNHCLDSAADVAGSEFWFNYQATTCAGTTSGALTKVAGDRMLKTNQTLDYTLLTVKNFASISSFGYLSLDVRKPVVGEEIYISGHPDTRMKELSVVSDRDGGGRCKVIDADADGYGTDTDAGYYCDTEGGNSGSPVLARSSHKVVALHHFGGNCNVAAPNRGVKMQLIWPQVSSYFGGVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAT9</accession>
    <name>A0A0S2DAT9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55569">
        <property type="protein sequence ID" value="ALN55569"/>
        <property type="gene ID" value="GLE_0210"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0210"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.212"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="78" mass="8667" checksum="B116CABDC6965FE7" modified="2016-02-17" version="1">MRRRLPSSRKHMLLLLLLLLLLLLLLLLLLLLLLLVLALEFQRSPADPEGARMDARVRHGTGCPLWRIPAPGAGLSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAU3</accession>
    <name>A0A0S2DAU3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0296</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945935.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0296"/>
    <dbReference type="EnsemblBacteria" id="ALN55654">
        <property type="protein sequence ID" value="ALN55654"/>
        <property type="gene ID" value="GLE_0296"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0296"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.295"/>
    <dbReference type="OMA" id="WATTHGE"/>
    <dbReference type="OrthoDB" id="1456605at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594793" evidence="1">
        <location>
            <begin position="24"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro_3" evidence="2">
        <location>
            <begin position="225"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="423" mass="46372" checksum="49209A1F4B36F668" modified="2016-02-17" version="1">MVHSFRLRWLVVGALFAAMGAAADPRATPPADGPARTIEFRDGRWFDGEGFRAGTWYSVDGALTRTRPARVDRVVDLDGGYATPPLAEGHNHDLQNAWGARRFRERYVEGGVQYAAMLCGDPGGTAEAKQALGADAPLDVLYASACISSSDGHPLAMARRDPDGSLRPVEDVHDHDYLVMDSRDDIERKWPRVRAARPDLIKAVLVHSERPERRGDARYFGMNGLRPELLAPLVERAHADGLRVVAHVESAADFRVAVEAGVDMIGHLPGYQIWEGRGEADYRLDDASIALAARRGTALIATAGAAQLVAGDDAGKLERVRALQRDNLRRLLAAGVPLALGSDRFDATVRAEIEYLSALKLMPPARLWRAAVEYTPSLLFPQRRIGRIAEGFEANFIVLDADPLRAPQALDRIRLKVRRGALY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAU8</accession>
    <name>A0A0S2DAU8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0297</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0297"/>
    <dbReference type="EnsemblBacteria" id="ALN55655">
        <property type="protein sequence ID" value="ALN55655"/>
        <property type="gene ID" value="GLE_0297"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0297"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.296"/>
    <dbReference type="OMA" id="HCIDNGV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010916">
        <property type="entry name" value="TonB_box_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00430">
        <property type="entry name" value="TONB_DEPENDENT_REC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595184" evidence="1">
        <location>
            <begin position="33"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="90"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="438" mass="46929" checksum="60EF5587C267BDCC" modified="2016-02-17" version="1">MMRHKNSKAPRAARTGLALACVALTLASPALAQQAPDTLVVTAARLFDASNGRLIENPQIVIHDGRISAVGRAGDAAPEGARRLDLPGMTVLPGLIDMHVHLDSDPSYGGYTGLQFSDRFWSVLAVKHAQQTLQAGFTTVRNVGADAWNDVGLRQAIDEGKLTGPRIVTAAYSFGATGGHCDSTYFPPSMAQKNPYNADSAAEARKSVRELRKYGAQVIKICATGGVFSRNTEPGQQQMSLEEMKAVADEAHQWGLRVAAHAHGAAGIHDAIRAGVDTIEHASLIDEEGIRLAKQHGAWLSMDIFNTDYTQAEGKKNGVLEDNLRKDREVGDIQRENFRRAHAAGVKMVYGTDAGVYPHGLNGKQFAVMTRYGMSPAQAIRAATFDAAQALGRKDVGLIEPGRWGDLIAVAGDPTQDVRLLESVPVVIKGGEVVKDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAV2</accession>
    <name>A0A0S2DAV2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8 10">Thymidine kinase</fullName>
            <ecNumber evidence="2 8 10">2.7.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">tdk</name>
        <name evidence="13" type="ORF">BV903_05715</name>
        <name evidence="15" type="ORF">D9T17_02260</name>
        <name evidence="14" type="ORF">FE772_01370</name>
        <name evidence="12" type="ORF">GLE_0089</name>
    </gene>
    <organism evidence="12 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 16">C3</strain>
        </source>
    </reference>
    <reference evidence="13 17" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 17">B25</strain>
        </source>
    </reference>
    <reference evidence="15 18" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 18">OH11</strain>
        </source>
    </reference>
    <reference evidence="14 19" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 19">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>ATP + thymidine = ADP + dTMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19129"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17748"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.21"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 11">Belongs to the thymidine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.21" evidence="2 8 10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000010">
        <property type="protein sequence ID" value="OPD64985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000006">
        <property type="protein sequence ID" value="ROU08928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945788.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0089"/>
    <dbReference type="EnsemblBacteria" id="ALN55448">
        <property type="protein sequence ID" value="ALN55448"/>
        <property type="gene ID" value="GLE_0089"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64985">
        <property type="protein sequence ID" value="OPD64985"/>
        <property type="gene ID" value="BV903_05715"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0089"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.94"/>
    <dbReference type="OMA" id="ENTVNHK"/>
    <dbReference type="OrthoDB" id="1279539at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004797">
        <property type="term" value="F:thymidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00124">
        <property type="entry name" value="Thymidine_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001267">
        <property type="entry name" value="Thymidine_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11441">
        <property type="entry name" value="PTHR11441"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00265">
        <property type="entry name" value="TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035805">
        <property type="entry name" value="TK_cell"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 10" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="6 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="9"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="88"/>
            <end position="91"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR035805-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN55448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OPD64985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW24526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROU08928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="208" mass="23039" checksum="CAAF20E5ED723779" modified="2016-02-17" version="1">MAKLYFYYSAMNAGKTTTLLQSAHNYRERGMRTAILTPHLDDRAGAGVVASRIGLRAEGVAFERDQDLEALIRADIAAHGALHCVLVDESQFLSRAQVWQLSEVVDALRIPVLCYGLRTDFRGELFEGSQYLLAWADELSEIKTICHSGKKATMNVRVDAAGRAVLDGPQVEIGGNDRYISVSRKEYKKVMRGEGTIEPLQQPLPLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAW1</accession>
    <name>A0A0S2DAW1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">7,8-dihydroneopterin aldolase</fullName>
            <ecNumber evidence="1">4.1.2.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">folB</name>
        <name evidence="4" type="ORF">FE772_02370</name>
        <name evidence="3" type="ORF">GLE_0311</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7,8-dihydroneopterin = 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde</text>
            <dbReference type="Rhea" id="RHEA:10540"/>
            <dbReference type="ChEBI" id="CHEBI:17001"/>
            <dbReference type="ChEBI" id="CHEBI:17071"/>
            <dbReference type="ChEBI" id="CHEBI:44841"/>
            <dbReference type="EC" id="4.1.2.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DHNA family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.25" evidence="1"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945944.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0311"/>
    <dbReference type="EnsemblBacteria" id="ALN55669">
        <property type="protein sequence ID" value="ALN55669"/>
        <property type="gene ID" value="GLE_0311"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0311"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.308"/>
    <dbReference type="OMA" id="GIYEWEK"/>
    <dbReference type="OrthoDB" id="1858654at2"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00154"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004150">
        <property type="term" value="F:dihydroneopterin aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00534">
        <property type="entry name" value="DHNA_DHNTPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006156">
        <property type="entry name" value="Dihydroneopterin_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006157">
        <property type="entry name" value="FolB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42844">
        <property type="entry name" value="PTHR42844"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02152">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00905">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00525">
        <property type="entry name" value="folB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00526">
        <property type="entry name" value="folB_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="1 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FolB" evidence="2">
        <location>
            <begin position="4"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="120" mass="13235" checksum="A962CC9D9EBCEBB3" modified="2016-02-17" version="1">MDHVFIEGLEIEAVIGIYDWEREIRQPLVFDLEMAFDNAVPAASDAIEHTLDYAAVCARITAFVAESRFGLVETLAERVAAIVIEEFGVRRVALKLTKPGAIRNARGVGVRIVREAAARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAX8</accession>
    <name>A0A0S2DAX8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4343 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_02455</name>
        <name evidence="2" type="ORF">GLE_0329</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945957.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0329"/>
    <dbReference type="EnsemblBacteria" id="ALN55687">
        <property type="protein sequence ID" value="ALN55687"/>
        <property type="gene ID" value="GLE_0329"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0329"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.326"/>
    <dbReference type="OMA" id="AWASGCY"/>
    <dbReference type="OrthoDB" id="1881710at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041261">
        <property type="entry name" value="R2K_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18299">
        <property type="entry name" value="R2K_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="R2K_2" evidence="1">
        <location>
            <begin position="82"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="244" mass="27408" checksum="FACBEBD64DC14AAA" modified="2016-02-17" version="1">MPTLILTPRHTDDAQALWKAASRQGWSIERLPGWRVPDRLRDLDDAVFYGEALFAPQIGAALGLRLDNPPEDWLPALPPEYRLREIGLSTLGAQRARTTPAFVKPPNDKSFPARVYTGAELPLGYDEDMPVLVAEVVRWRCELRCFVLDRRLRTWSLYSREGDLARDSGFASSDEEDAQATAFLQRMLDDPRVALPRACVIDVGYIEDRGWACVEQNAAWGAGLYACDAEQALEVIRHASVRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB20</accession>
    <name>A0A0S2DB20_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">KAP family P-loop domain protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">NTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_02695</name>
        <name evidence="2" type="ORF">GLE_0381</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0381"/>
    <dbReference type="EnsemblBacteria" id="ALN55739">
        <property type="protein sequence ID" value="ALN55739"/>
        <property type="gene ID" value="GLE_0381"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0381"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.378"/>
    <dbReference type="OMA" id="NPWWFSG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011646">
        <property type="entry name" value="KAP_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07693">
        <property type="entry name" value="KAP_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KAP NTPase" evidence="1">
        <location>
            <begin position="24"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="723" mass="80227" checksum="F06BD020E9710713" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB50</accession>
    <name>A0A0S2DB50_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55753">
        <property type="protein sequence ID" value="ALN55753"/>
        <property type="gene ID" value="GLE_0395"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0395"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.392"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="290" mass="31195" checksum="5917D2B7FF78D240" modified="2016-02-17" version="1">MGQGGSTGRLTLDQRLLTYSHQSTDASPEKITLSGIKDYMGSNDALSAGHYSNRSDKVEAYNTLSRITAASAMSDERRYDLRTQAYRDFNRNGAMLEKAGIEPPQPPQKEQAATSSQTASKLPEDIQRDLKALLANPHSFLSLNGRGIEAYENCQHKDLRSAIHADQEFVEKGAKYWTLPDDGKRAGIAESWSGHLQSADAHNSVGVHATNRTPIDAIRGAQAELTTAINGGYDITQKGAQNAFSQVALGVNLALNSAQTLAGRGADTVAEQTMLQSPDGHSNQGPTRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB83</accession>
    <name>A0A0S2DB83_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0339</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55697">
        <property type="protein sequence ID" value="ALN55697"/>
        <property type="gene ID" value="GLE_0339"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0339"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.336"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="79" mass="9164" checksum="064F28CE1E28366D" modified="2016-02-17" version="1">MRHGSPPERCVLWPRAHCRRAASAAASGPRSGRMLGMPYGLQRVLHTYSWDAVAFMSQFRPRLRHEYVCRRGGRRGRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB84</accession>
    <name>A0A0S2DB84_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lysine-specific histone demethylase 1</fullName>
            <ecNumber evidence="2">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.-.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55808">
        <property type="protein sequence ID" value="ALN55808"/>
        <property type="gene ID" value="GLE_0450"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0450"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="88" mass="9136" checksum="4E71C045F3EC01F2" modified="2016-02-17" version="1">MVAPRPGSSPVEAARSGPDPLAAGHTRRQRPSLASPRAGFEAEAAPCGGSNVEPAAETPPPAGLHRPKARHPQGRRTSDNLEPQLAVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB94</accession>
    <name>A0A0S2DB94_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Endonuclea_NS_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0303</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945938.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0303"/>
    <dbReference type="EnsemblBacteria" id="ALN55661">
        <property type="protein sequence ID" value="ALN55661"/>
        <property type="gene ID" value="GLE_0303"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0303"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.300"/>
    <dbReference type="OrthoDB" id="1060802at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044927">
        <property type="entry name" value="Endonuclea_NS_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13930">
        <property type="entry name" value="Endonuclea_NS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclea_NS_2" evidence="2">
        <location>
            <begin position="161"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="316" mass="34048" checksum="D5E0F6BE5778FD6E" modified="2016-02-17" version="1">MSDPIHAGLPARPAPLPPPAALPQALRDAPAPLARAQVDALDRDGVQALGDEVAALPLAERESLANELAGKLDAPQLRKLEPAFGRDTIAEAVERRGGPELREAYAALPREDGPVARFVDGIQRALGLSADDAPVDRADPGQTREVSASVTNPDGGEINDATWTVDDQGRPLHAEGTLRTVFSEIDRSDAETAAQRTAADRGIDGDQGGHLLGHRFVTDQGLKNLFPQNGNFNMGAYKTLENEWAAWIDKGMDVRVSIDLSPREADRPDRVRISYEVLDPADGHRVYDQRVSFDNRAGQSYDRIDTGEMDGLIAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBA5</accession>
    <name>A0A0S2DBA5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55576">
        <property type="protein sequence ID" value="ALN55576"/>
        <property type="gene ID" value="GLE_0217"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0217"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.219"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="286" mass="31726" checksum="F0C3CEAE81D776DA" modified="2016-02-17" version="1">MGSGFRRNDGRGVAYPTVGAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAAGSLSLSEATKKVTKEKALFFRIKSHYGSKGARGRAIRGILPHGARAHPCARPPGLRNMGFVRGCVQAKSKAQQRQWQRQRQRQRQDQNGFRXXXXXXXRERTSPPAVIPAKAGIHFDFVVPARSRACRVLWSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBH7</accession>
    <name>A0A0S2DBH7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55878">
        <property type="protein sequence ID" value="ALN55878"/>
        <property type="gene ID" value="GLE_0520"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0520"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.515"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="68" mass="7335" checksum="3272205438EECD38" modified="2016-02-17" version="1">MTAAAIGQIAEIAEIGGFGRRSRGRRRLVASTSTRLRQCIRRDLPRSAAMTAGPTAMPREPRAVASRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBL9</accession>
    <name>A0A0S2DBL9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YcaO-like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_02865</name>
        <name evidence="2" type="ORF">GLE_0415</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946018.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55773">
        <property type="protein sequence ID" value="ALN55773"/>
        <property type="gene ID" value="GLE_0415"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0415"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.412"/>
    <dbReference type="OMA" id="SINNHAY"/>
    <dbReference type="OrthoDB" id="735222at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003776">
        <property type="entry name" value="YcaO-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02624">
        <property type="entry name" value="YcaO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51664">
        <property type="entry name" value="YCAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YcaO" evidence="1">
        <location>
            <begin position="55"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="424" mass="46670" checksum="9C22374F85A6A9F9" modified="2016-02-17" version="1">MIPYERERSLEDADRIIRASIARRGWCIDTDRLGDGLVTAKCFLLDGDGRVLAFGGGKGEPDAAYTGAVYEAVEHHYCKAATLPQQWDYPSAGSIAEDPRYAALPFLSALAEQPQRRLACRSYTAYSGDDTLPVPLFLSFPDYPGSPRATDPRDDFDYASALRFGSNSGTAIGGSFEEAALHGIGEIVERDAWSLFLIAHHLGGDARYGRWIEPASLPDELARAQRIAEARIGCALRLIDITTDLAYPAFIAVAERRLEDEVVYSHGCGASPYPRHAALRALSELVQCVDIKRDTEHLADLDRLSLELLAPYPRLRDCAMGEIDPRRLHRASWDFAEPARAAPRQLLPTVVADLRARGLPLYYAINHREGDDFCVVSSLSPELERFFLVTTGVAMAPGRRGQAFLRKLRRAEAGAGERALPAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBR0</accession>
    <name>A0A0S2DBR0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0479</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55837">
        <property type="protein sequence ID" value="ALN55837"/>
        <property type="gene ID" value="GLE_0479"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0479"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="39" mass="4473" checksum="55D977EFBD128DF3" modified="2016-02-17" version="1">MRRAWFSCARISHRYRRIDGVGAATKVRGDHGRGRCPCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC70</accession>
    <name>A0A0S2DC70_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA pyrophosphohydrolase</fullName>
            <ecNumber evidence="3">3.6.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">(Di)nucleoside polyphosphate hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rppH</name>
        <name evidence="3" type="synonym">nudH</name>
        <name evidence="8" type="ORF">BV903_22470</name>
        <name evidence="10" type="ORF">D9T17_23545</name>
        <name evidence="9" type="ORF">FE772_04300</name>
        <name evidence="7" type="ORF">GLE_0721</name>
    </gene>
    <organism evidence="7 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 11">C3</strain>
        </source>
    </reference>
    <reference evidence="8 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">OH11</strain>
        </source>
    </reference>
    <reference evidence="9 14" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nudix hydrolase family. RppH subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000075">
        <property type="protein sequence ID" value="OPD61667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000059">
        <property type="protein sequence ID" value="ROU04529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946248.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000059.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0721"/>
    <dbReference type="EnsemblBacteria" id="ALN56079">
        <property type="protein sequence ID" value="ALN56079"/>
        <property type="gene ID" value="GLE_0721"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61667">
        <property type="protein sequence ID" value="OPD61667"/>
        <property type="gene ID" value="BV903_22470"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0721"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.709"/>
    <dbReference type="OMA" id="PCVGIML"/>
    <dbReference type="OrthoDB" id="1345242at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016462">
        <property type="term" value="F:pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd03671">
        <property type="entry name" value="Ap4A_hydrolase_plant_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00298">
        <property type="entry name" value="Nudix_RppH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022927">
        <property type="entry name" value="RppH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="6">
        <location>
            <begin position="6"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="165"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Nudix box" evidence="3">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="173"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN56079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD61667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW25008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROU04529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="208" mass="23802" checksum="8DC287BB28C4E7F0" modified="2016-02-17" version="1">MIDPDGYRPNVGIVLMHPDGRLFWARRVHRDGWQFPQGGMNSDETPLEAMYRELREETGLQPHHVEVLGATPGWLRYRLPRRAVRRNDRLVCIGQKQVWFLLRLTGQESDLCLDVTDKPEFDHWRWVDFWYPIEHVVMFKRGVYTSALRHLAPFARHVAGDQAVPMPCPVADARPDPRRDAGLGGRQHQRPRARPGGQSACGGSEPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCB0</accession>
    <name>A0A0S2DCB0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CRP-like protein Clp</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Catabolite activation-like protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FE772_03880</name>
        <name evidence="12" type="ORF">GLE_0634</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">C3</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">YC36</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946177.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0634"/>
    <dbReference type="EnsemblBacteria" id="ALN55992">
        <property type="protein sequence ID" value="ALN55992"/>
        <property type="gene ID" value="GLE_0634"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0634"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.623"/>
    <dbReference type="OMA" id="FCSTCAF"/>
    <dbReference type="OrthoDB" id="1587662at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00034">
        <property type="entry name" value="HTHCRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="6" id="KW-0973">c-di-GMP</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="7" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="10">
        <location>
            <begin position="37"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="HTH crp-type" evidence="11">
        <location>
            <begin position="167"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN55992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW24936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="253" mass="27973" checksum="DD23F889B52CE429" modified="2016-02-17" version="1">MLLDRTVPAEPSLAADFAAADFADDGCAAASQAGDAALESWLQRELPRLGLPLQRRRLRAKQHVFRAGQPRTALYLVHAGFFKTALVSEDGREKITGFRMRGDLLGLDALDMNAYACDAVALDTGELWEVPFARLRNERPQFQERITALLAQEIRRDWNWMLALGTLGADQRVVTFLFDLAARLQTLGFSGECLQLRMTRAELGNFLSLTLETVARSLSRLQARGLIEVAGREIVLRDRVALSGLLAAGGRVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCM5</accession>
    <name>A0A0S2DCM5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase</fullName>
            <ecNumber evidence="3">3.1.7.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BV903_19760</name>
        <name evidence="10" type="ORF">FE772_05215</name>
        <name evidence="8" type="ORF">GLE_0912</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine 3',5'-bis(diphosphate) + H2O = diphosphate + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14253"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:77828"/>
            <dbReference type="EC" id="3.1.7.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; ppGpp biosynthesis; ppGpp from GDP: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the relA/spoT family.</text>
    </comment>
    <dbReference type="EC" id="3.1.7.2" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000057">
        <property type="protein sequence ID" value="OPD62227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946390.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000057.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0912"/>
    <dbReference type="EnsemblBacteria" id="ALN56270">
        <property type="protein sequence ID" value="ALN56270"/>
        <property type="gene ID" value="GLE_0912"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62227">
        <property type="protein sequence ID" value="OPD62227"/>
        <property type="gene ID" value="BV903_19760"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0912"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.900"/>
    <dbReference type="OMA" id="DWISSPK"/>
    <dbReference type="OrthoDB" id="204079at2"/>
    <dbReference type="UniPathway" id="UPA00908">
        <property type="reaction ID" value="UER00886"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015970">
        <property type="term" value="P:guanosine tetraphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05399">
        <property type="entry name" value="NT_Rel-Spo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01668">
        <property type="entry name" value="TGS_RSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004811">
        <property type="entry name" value="RelA/Spo_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045600">
        <property type="entry name" value="RelA/SpoT_AH_RIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007685">
        <property type="entry name" value="RelA_SpoT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033655">
        <property type="entry name" value="TGS_RelA/SpoT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13291">
        <property type="entry name" value="ACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19296">
        <property type="entry name" value="DUF5913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04607">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00954">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00691">
        <property type="entry name" value="spoT_relA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HD" evidence="6">
        <location>
            <begin position="64"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="7">
        <location>
            <begin position="405"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="5">
        <location>
            <begin position="654"/>
            <end position="726"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN56270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD62227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW25154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="726" mass="81205" checksum="8E4CCE82BEC4F48A" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCT0</accession>
    <name>A0A0S2DCT0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0976</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946432.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0976"/>
    <dbReference type="EnsemblBacteria" id="ALN56334">
        <property type="protein sequence ID" value="ALN56334"/>
        <property type="gene ID" value="GLE_0976"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0976"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.963"/>
    <dbReference type="OMA" id="GEGPWYR"/>
    <dbReference type="OrthoDB" id="1639777at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025060">
        <property type="entry name" value="DUF3999"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13163">
        <property type="entry name" value="DUF3999"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594938" evidence="2">
        <location>
            <begin position="20"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="429"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="458" mass="49268" checksum="DED517A6FCF835BA" modified="2016-02-17" version="1">MKSRSLTLALLVLALPLAAAPRQDYARQWPLQLSRDDGGAYRVELDPAVYAQAHSAQLRDIDVIDAGGAIVPAEVFAPEQPLARAPQRRSLPWFPLPAAPAGTNKGWELISEVETDGRLRRVEARSTAGDTAKLPQTALLIDASAVRAPIQALQLQWAPGAALDAAYSVEASDDLDHWRSVTSSGRLLDLQRDGQRLVQRRIAFDAVGEQARYLRLTPQDPQRGAQIVAVEAELSATAAGAPLQWRELKGARVQLKDGGVAFEYRLDGRFPIQQADVALPGNHALQWRLDSRDSEDEGWRAQAGPWMAYAVAGQGAGDRSPARQLASASRDRLWRLRASGAVPGEPVLRLGYRPEVVVFLAQGQPPYALVAGSGRAARADSPLSQLVDALRQSRGNDWRPAEASLGAPGDLAGAAALAAPEPERDWRSWLLWAVLVGGALIVVGFAMSLLRSGKAPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD69</accession>
    <name>A0A0S2DD69_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_1144</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1144"/>
    <dbReference type="EnsemblBacteria" id="ALN56502">
        <property type="protein sequence ID" value="ALN56502"/>
        <property type="gene ID" value="GLE_1144"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1144"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1129"/>
    <dbReference type="OMA" id="FQKMENG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011110">
        <property type="entry name" value="Reg_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011123">
        <property type="entry name" value="Y_Y_Y"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07494">
        <property type="entry name" value="Reg_prop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07495">
        <property type="entry name" value="Y_Y_Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="798"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="856"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="1099"/>
            <end position="1213"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="1148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN56502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1220" mass="132076" checksum="8E98892C5035223B" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDB2</accession>
    <name>A0A0S2DDB2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">Aminoglycoside N(6')-acetyltransferase type 1</fullName>
            <ecNumber evidence="3 7">2.3.1.82</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Aminoglycoside resistance protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLE_1155</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the transfer of an acetyl group from acetyl-CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>acetyl-CoA + kanamycin B = CoA + H(+) + N(6')-acetylkanamycin B</text>
            <dbReference type="Rhea" id="RHEA:16449"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58390"/>
            <dbReference type="ChEBI" id="CHEBI:58549"/>
            <dbReference type="EC" id="2.3.1.82"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2 7">Homodimer.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.82" evidence="3 7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946559.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56513">
        <property type="protein sequence ID" value="ALN56513"/>
        <property type="gene ID" value="GLE_1155"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1155"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1140"/>
    <dbReference type="OMA" id="DYVNGCS"/>
    <dbReference type="OrthoDB" id="2055010at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047663">
        <property type="term" value="F:aminoglycoside 6'-N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024170">
        <property type="entry name" value="Aminoglycoside_N6-AcTrfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000452">
        <property type="entry name" value="6-N-acetyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="8">
        <location>
            <begin position="5"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="152" mass="16776" checksum="78AD45538EA1A350" modified="2016-02-17" version="1">MTQPWRVRAAAPADRAAWATLRAQLWPEQPLAELAADLDGWFEDARLAAFIAEDGEGVCGFAEASLRSDYVNGTESSPVAFLEGWYVAPSHRGRGVGRALVATVEAWGRERGCRELASDALLDNLDSHRAHAACGFEETERVVYFRRRLDAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDD6</accession>
    <name>A0A0S2DDD6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HAD family hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase-like hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_06585</name>
        <name evidence="1" type="ORF">GLE_1214</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946603.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1214"/>
    <dbReference type="EnsemblBacteria" id="ALN56571">
        <property type="protein sequence ID" value="ALN56571"/>
        <property type="gene ID" value="GLE_1214"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1214"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1199"/>
    <dbReference type="OMA" id="TWPGILE"/>
    <dbReference type="OrthoDB" id="1484726at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="229" mass="24240" checksum="B442B78FF2704672" modified="2016-02-17" version="1">MDYRLALFDIAGTTVSDPGFVAQAFVGAMGAAGHPIDPEQCRALMGYRKPEAIARLLGAAATPAKIEAIHDDFVQRMLRCYREQPGVAPLPGAESTFALLRAHGIKVALNTGFSRDIAEAILTRLGWNERIDALIASDEVPAGRPAPHMAQALLRRFGLNDARQLVKIGDTEVDIGEGRNAGAGLVVAVTTGAFARAELEPYAPDAIVDSLFELPALLGIDAVARDDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDL0</accession>
    <name>A0A0S2DDL0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HutD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_06715</name>
        <name evidence="1" type="ORF">GLE_1242</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946621.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1242"/>
    <dbReference type="EnsemblBacteria" id="ALN56599">
        <property type="protein sequence ID" value="ALN56599"/>
        <property type="gene ID" value="GLE_1242"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1242"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1226"/>
    <dbReference type="OMA" id="THDFNLM"/>
    <dbReference type="OrthoDB" id="1912404at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010282">
        <property type="entry name" value="Uncharacterised_HutD/Ves"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37943">
        <property type="entry name" value="PTHR37943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05962">
        <property type="entry name" value="HutD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="205" mass="23018" checksum="C035AC121EB36DEC" modified="2016-02-17" version="1">MPTRPSWCIPANEYRRERWRNQFGWTREIVRMRREAGRDRPAAGEEDWDWRLSIAEIESDAPFSAFPGVDRELVLLSGNGLRLCFDDGEAVELHPPHDKLRFAGERTVTGELIDGPTHDFNLMWRRGRVRAELWHRPLVGPMVLFAEPGQSWAVHLLAGQAHFADGSGLAPLQAGDTAILAAGEDRLRHVLEGGGEVLLVRVGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDQ0</accession>
    <name>A0A0S2DDQ0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dipeptidyl-peptidase</fullName>
            <ecNumber evidence="2">3.4.14.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_07070</name>
        <name evidence="3" type="ORF">GLE_1320</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase S46 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.14.-" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946686.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1320"/>
    <dbReference type="EnsemblBacteria" id="ALN56677">
        <property type="protein sequence ID" value="ALN56677"/>
        <property type="gene ID" value="GLE_1320"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1320"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1304"/>
    <dbReference type="OMA" id="ADTDNWM"/>
    <dbReference type="OrthoDB" id="99817at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070009">
        <property type="term" value="F:serine-type aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019500">
        <property type="entry name" value="Pep_S46"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38469">
        <property type="entry name" value="PTHR38469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10459">
        <property type="entry name" value="Peptidase_S46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0720">Serine protease</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033769748" description="Dipeptidyl-peptidase" evidence="2">
        <location>
            <begin position="20"/>
            <end position="718"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU366067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="718" mass="79125" checksum="1D09C36483E82105" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDQ6</accession>
    <name>A0A0S2DDQ6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 4">Imidazolonepropionase</fullName>
            <ecNumber evidence="1 4">3.5.2.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Imidazolone-5-propionate hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">hutI</name>
        <name evidence="6" type="ORF">GLE_1359</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>4-imidazolone-5-propanoate + H2O = N-formimidoyl-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23660"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58928"/>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
            <dbReference type="EC" id="3.5.2.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="4">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc or iron ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid degradation; L-histidine degradation into L-glutamate; N-formimidoyl-L-glutamate from L-histidine: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-dependent hydrolases superfamily. HutI family.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.7" evidence="1 4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1359"/>
    <dbReference type="EnsemblBacteria" id="ALN56716">
        <property type="protein sequence ID" value="ALN56716"/>
        <property type="gene ID" value="GLE_1359"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1359"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1341"/>
    <dbReference type="OMA" id="CAPHARW"/>
    <dbReference type="UniPathway" id="UPA00379">
        <property type="reaction ID" value="UER00551"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050480">
        <property type="term" value="F:imidazolonepropionase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019556">
        <property type="term" value="P:histidine catabolic process to glutamate and formamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019557">
        <property type="term" value="P:histidine catabolic process to glutamate and formate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01296">
        <property type="entry name" value="Imidazolone-5PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00372">
        <property type="entry name" value="HutI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005920">
        <property type="entry name" value="HutI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42752">
        <property type="entry name" value="PTHR42752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01224">
        <property type="entry name" value="hutI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0369">Histidine metabolism</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="5">
        <location>
            <begin position="129"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>4-imidazolone-5-propanoate</name>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>4-imidazolone-5-propanoate</name>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>4-imidazolone-5-propanoate</name>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="381"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="383"/>
        </location>
        <ligand>
            <name>N-formimidoyl-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58928"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="385"/>
        </location>
        <ligand>
            <name>N-formimidoyl-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58928"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="386"/>
        </location>
        <ligand>
            <name>4-imidazolone-5-propanoate</name>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN56716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="469" mass="49844" checksum="AF1E33BB1634194B" modified="2016-02-17" version="1">MAFMAGILARAAAEENRRGAVLPKPAAHGARIGTMRRRTQPGAAAATRIAAMTSSSPAPDRPPYDSLPYDGLILGASLATLDAAAGYGEIADAALAWRDGRIAWLGPRAQLPAAPEALAAQVIQASGWITPGLIDCHTHLIFAGDRAREFELRLQGASYEEIARAGGGIVSSVRAVREADEDELLRQSLPRARALIADGATTLEIKSGYGLDFDNERKMLRVARRLGETLGVRVRTTYLAAHALPPEYQGRADDYIDAACRWLPRLHAEGLVDAVDAFCEGIGFSPAQTTRMFEAARALDLPVKLHADQLSDLGGGALAAAFDGLSADHVEHTSLDSVRAMAAHGTVAVLLPGAFHVLRETKLPPLDAFREHGVAMALATDCNPGTSPLLSLRQAMQLSCTHFRLTPEEALRGATVHAAKALGLGDAGALKVGASADFALWDIRHPAELCYWLGGRLAQRVYCQGRQIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE60</accession>
    <name>A0A0S2DE60_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Spermidine N(1)-acetyltransferase</fullName>
            <ecNumber evidence="2 4">2.3.1.57</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Spermidine N1-acetyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Spermidine acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">speG</name>
        <name evidence="3" type="ORF">BV903_13095</name>
        <name evidence="4" type="ORF">FE772_07540</name>
        <name evidence="2" type="ORF">GLE_1429</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.57" evidence="2 4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000033">
        <property type="protein sequence ID" value="OPD63470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946769.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1429"/>
    <dbReference type="EnsemblBacteria" id="ALN56786">
        <property type="protein sequence ID" value="ALN56786"/>
        <property type="gene ID" value="GLE_1429"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63470">
        <property type="protein sequence ID" value="OPD63470"/>
        <property type="gene ID" value="BV903_13095"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1429"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1410"/>
    <dbReference type="OMA" id="IYEAKQL"/>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004145">
        <property type="term" value="F:diamine N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="20"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="189" mass="22054" checksum="26FFC3B8A3018A58" modified="2016-02-17" version="1">MTSTPIDESSASAAAAPGGLTLRPLERGDLHFIHVLNNNRSVMGYWFEEPYESFVELEELYRKHIHDQSERRFIIQDGAMERIGLVELVEIDHLHRRAEFLIMISPEHQRRGHARLATRLAINYAFRVLNLYKLYLLVDVDNTRAIRIYEDAGFQREGVLVDEFFTDGRYHDVVRMCLFQHQVLGRVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DED4</accession>
    <name>A0A0S2DED4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1564</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56921">
        <property type="protein sequence ID" value="ALN56921"/>
        <property type="gene ID" value="GLE_1564"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1564"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1544"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="317" mass="33789" checksum="4CAA025804C1AB39" modified="2016-02-17" version="1">MGHRSVRSRVVLQVVGGGAARSLKRAPRPRARPEPARRARGRRGRCAPSQRRAGCVAARKLTNLVACVCIENATSLRSPGACAVSGAWVRSVSGCGRSLRNARARKSAAAAAARNVGRRGAAGCAGTGDAGVRVRIRRSKHRTQKGGDKKSRPGATPRGRHRLAAEGDQPQQSRVDERRGRARSGRGSKARWSAKPRQRPRDREGTEGSPARAAKASRRPDANIGAARDGRQGRAAMRIEQSGGDDMAATVAARADRELDAAHSAERRRAPGYGGRSARLQQDYIEAYAVADFRRTRGFAVAARAAATGTAPWPVRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEE6</accession>
    <name>A0A0S2DEE6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transglycosylase SLT domain/LysM domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_1657</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transglycosylase Slt family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946952.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1657"/>
    <dbReference type="EnsemblBacteria" id="ALN57014">
        <property type="protein sequence ID" value="ALN57014"/>
        <property type="gene ID" value="GLE_1657"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1657"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1636"/>
    <dbReference type="OrthoDB" id="1444566at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008933">
        <property type="term" value="F:lytic transglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000270">
        <property type="term" value="P:peptidoglycan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000189">
        <property type="entry name" value="Transglyc_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008258">
        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00922">
        <property type="entry name" value="TRANSGLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="457"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="344"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="359"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="509" mass="54157" checksum="2C2513B9C8DE3F80" modified="2016-02-17" version="1">MSGPRDRRTPARPRPERRPADAAGPRAAPRRRRLLAALAAGLCWLTALPASAAEAPTAAPQESGPTRNGREIYRSFRDGLADQSCEPGVSTRWRQHFANAPRRLAAKDDDLLPLFGYVVDALRENHLPTEYALIPFVESGYRPGARSAAGPAGLWQMIAITARNHRVPMREGYDGRLSPVESTQAAVRYLKTLHGMFGGDWRLAVMAYNAGEYRVFNAIKRAGVNIADARHDQLTGLSDITTAYVRKLHALSCLMEQADDREEWLSALDRPVPRLAAVTVPDGVDSIGEWAARTDQDVAWLQRLNPAFGDGRIGRPGGRRAPLLAVAANAVGAPAAAAPELATASGELPPSEGRATAAAPSKPDERADKESRPLAALKPGETAQADAKAMAAVKPAEPAKNGPAAPKPGDAAKSEARLAAHATRDGEPTTLGSAEDARVEPLARPAKPQRAQATAPRKHTVGRGENPWTIAKRYGVRAADLLKLNGLAAGAVLKPGQALLIDPPAGKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEJ4</accession>
    <name>A0A0S2DEJ4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_12630</name>
        <name evidence="3" type="ORF">FE772_08190</name>
        <name evidence="1" type="ORF">GLE_1573</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000031">
        <property type="protein sequence ID" value="OPD63560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946886.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1573"/>
    <dbReference type="EnsemblBacteria" id="ALN56930">
        <property type="protein sequence ID" value="ALN56930"/>
        <property type="gene ID" value="GLE_1573"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63560">
        <property type="protein sequence ID" value="OPD63560"/>
        <property type="gene ID" value="BV903_12630"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1573"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1553"/>
    <dbReference type="OMA" id="ADMDAWG"/>
    <dbReference type="OrthoDB" id="1387377at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD63560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="157" mass="16988" checksum="5A0F1EA27BBF85BD" modified="2016-02-17" version="1">MLTLADIGFDDAATLLARYGLALVRVADGDAIPGSYWGDSEAGIIASTVYARADTPVHSMLHEACHLIVLPPQRRAAVHTDATDSVEEEDAVLVLQTVLADALPGVGRERMYADMDAWGYTFRLGSAKAYVEQDAQTSWQWLAERGLVEAPQRTQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF34</accession>
    <name>A0A0S2DF34_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA topoisomerase 4 subunit A</fullName>
            <ecNumber evidence="5">5.6.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Topoisomerase IV subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">parC</name>
        <name evidence="8" type="ORF">FE772_09145</name>
        <name evidence="7" type="ORF">GLE_1776</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterotetramer composed of ParC and ParE.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947042.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1776"/>
    <dbReference type="EnsemblBacteria" id="ALN57130">
        <property type="protein sequence ID" value="ALN57130"/>
        <property type="gene ID" value="GLE_1776"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1776"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1751"/>
    <dbReference type="OMA" id="PRSNRID"/>
    <dbReference type="OrthoDB" id="217468at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019897">
        <property type="term" value="C:extrinsic component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00187">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00936">
        <property type="entry name" value="ParC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035516">
        <property type="entry name" value="Gyrase/topoIV_suA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005742">
        <property type="entry name" value="TopoIV_A_Gneg"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101904">
        <property type="entry name" value="SSF101904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="TOP4c" evidence="6">
        <location>
            <begin position="15"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="5">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="5">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="5">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="5">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="5">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW25805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="747" mass="82256" checksum="EDC3755A5C2B9E33" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF65</accession>
    <name>A0A0S2DF65_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytidine and deoxycytidylate deaminase zinc-binding region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_1828</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1828"/>
    <dbReference type="EnsemblBacteria" id="ALN57180">
        <property type="protein sequence ID" value="ALN57180"/>
        <property type="gene ID" value="GLE_1828"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1828"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1799"/>
    <dbReference type="OMA" id="MCHAAMR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008251">
        <property type="term" value="F:tRNA-specific adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002100">
        <property type="term" value="P:tRNA wobble adenosine to inosine editing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028883">
        <property type="entry name" value="tRNA_aden_deaminase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14437">
        <property type="entry name" value="MafB19-deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="3">
        <location>
            <begin position="8"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="157" mass="16875" checksum="0749EC1CD12AE336" modified="2016-02-17" version="1">MNDRPADPRHLEFMRQALALARANAAAGGRPFGAVLVRDGQVLARAVNRILDTGDPTAHAELLAIREAAHALGLTRLEGCTIYASGHPCPMCLAAMHLAGIEAAYYAYSNEDGEPFGLSTAAVYAQMALPPARQRLPLRQLRPDAEDGLYAQWAQRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFA1</accession>
    <name>A0A0S2DFA1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF1318 domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_08870</name>
        <name evidence="3" type="ORF">GLE_1715</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946999.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1715"/>
    <dbReference type="EnsemblBacteria" id="ALN57070">
        <property type="protein sequence ID" value="ALN57070"/>
        <property type="gene ID" value="GLE_1715"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1715"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1693"/>
    <dbReference type="OMA" id="ETFARRW"/>
    <dbReference type="OrthoDB" id="1714881at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008309">
        <property type="entry name" value="UCP025560"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07027">
        <property type="entry name" value="DUF1318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242133" evidence="2">
        <location>
            <begin position="30"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="211" mass="22831" checksum="30DAE3AF6146CEF7" modified="2016-02-17" version="1">MRRWMGVPVAAVMLTACVTINVYFPAAEAKEAAKEFVEKVIGDTPAAQPQAQPSEGGKSGGSAALDRPSLRWGELASRIDWWSVAGIGSARAQSPDISIKTPAIQAIQSRMAQRFDSQLRAQFDSGALGFASNGTVSVRDAAKIPLSDRVGVNQAVADQNRDSNAVYKEIAVANNHPEWEGQIRQVFSKQWIESAKGGWWYQDAGGAWKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFD7</accession>
    <name>A0A0S2DFD7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Alpha-lytic protease prodomain/trypsin</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="12">S1 family peptidase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="11">Serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BV903_10965</name>
        <name evidence="12" type="ORF">FE772_10115</name>
        <name evidence="10" type="ORF">GLE_1989</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">C3</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000025">
        <property type="protein sequence ID" value="OPD63918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947193.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1989"/>
    <dbReference type="EnsemblBacteria" id="ALN57339">
        <property type="protein sequence ID" value="ALN57339"/>
        <property type="gene ID" value="GLE_1989"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63918">
        <property type="protein sequence ID" value="OPD63918"/>
        <property type="gene ID" value="BV903_10965"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1989"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1956"/>
    <dbReference type="OMA" id="YSIIRAD"/>
    <dbReference type="OrthoDB" id="1110723at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.50">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037295">
        <property type="entry name" value="Alpha-lytic_protease_prodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004236">
        <property type="entry name" value="Pept_S1_alpha_lytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001316">
        <property type="entry name" value="Pept_S1A_streptogrisin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035070">
        <property type="entry name" value="Streptogrisin_prodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02983">
        <property type="entry name" value="Pro_Al_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001134">
        <property type="entry name" value="Streptogrisin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00861">
        <property type="entry name" value="ALYTICPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54806">
        <property type="entry name" value="SSF54806"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 10" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594761" evidence="7">
        <location>
            <begin position="24"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="Pro_Al_protease" evidence="9">
        <location>
            <begin position="109"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="8">
        <location>
            <begin position="221"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="350"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="302"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="344"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001134-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001134-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN57339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OPD63918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW25970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="404" mass="41246" checksum="7D397F142F8694C5" modified="2016-02-17" version="1">MRKIRLSVLAAAVALTASGAALAADDLPAGLKTAMQRDLGLSGNELAQYLKAERLAAAQEKTVEKQLGRNFAGAWLERKADGSFGFVAATTSIKAAKAAAGVETRQARHSLAALNAAKGQLDSQLARNGKAPKGVYSWAVDLPSNSVVVGVAPGSEDAAVDFVALSGLDSTAVRFETLAEAPRRLNNIQGGRGYLRNPGDGYLYACSVGFSVTKGTTPGFATAGHCGDTGEVVYNEDSQWTPGARLGAFAASSMPDGNQTGPDRGWVQVDSNHTLLASVYGYGNGDVAVRGSTEGAVGAALCRSGRTSGWRCGAIRTKNVTVSYVDDNNQPDGTVTGLTQTTACAEGGDSGGSYITSAGQAQGVLSGGSGSCKGKQGRTGGGNSYFTPINSILSAYSLTLKTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFG2</accession>
    <name>A0A0S2DFG2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DnaK family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Molecular chaperone HscC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_10000</name>
        <name evidence="5" type="ORF">GLE_1966</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947176.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1966"/>
    <dbReference type="EnsemblBacteria" id="ALN57317">
        <property type="protein sequence ID" value="ALN57317"/>
        <property type="gene ID" value="GLE_1966"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1966"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1931"/>
    <dbReference type="OMA" id="GHYLPII"/>
    <dbReference type="OrthoDB" id="161217at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10235">
        <property type="entry name" value="HscC_like_NBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042030">
        <property type="entry name" value="HscC_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="SSF100920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW25948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="564" mass="61758" checksum="D88A8F99E1EF3A2A" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFI6</accession>
    <name>A0A0S2DFI6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cysteine--tRNA ligase</fullName>
            <ecNumber evidence="11">6.1.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Cysteinyl-tRNA synthetase</fullName>
            <shortName evidence="11">CysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 13" type="primary">cysS</name>
        <name evidence="14" type="ORF">FE772_09400</name>
        <name evidence="13" type="ORF">GLE_1832</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">C3</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys)</text>
            <dbReference type="Rhea" id="RHEA:17773"/>
            <dbReference type="Rhea" id="RHEA-COMP:9661"/>
            <dbReference type="Rhea" id="RHEA-COMP:9679"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78517"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 11">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.16" evidence="11"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947080.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1832"/>
    <dbReference type="EnsemblBacteria" id="ALN57184">
        <property type="protein sequence ID" value="ALN57184"/>
        <property type="gene ID" value="GLE_1832"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1832"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1803"/>
    <dbReference type="OMA" id="AKYWMHN"/>
    <dbReference type="OrthoDB" id="952207at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004817">
        <property type="term" value="F:cysteine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006423">
        <property type="term" value="P:cysteinyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00672">
        <property type="entry name" value="CysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00041">
        <property type="entry name" value="Cys_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015803">
        <property type="entry name" value="Cys-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015273">
        <property type="entry name" value="Cys-tRNA-synt_Ia_DALR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032678">
        <property type="entry name" value="tRNA-synt_1_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="PTHR10890"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09190">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01406">
        <property type="entry name" value="tRNA-synt_1e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00983">
        <property type="entry name" value="TRNASYNTHCYS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00840">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00435">
        <property type="entry name" value="cysS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11 13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 11 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="DALR_2" evidence="12">
        <location>
            <begin position="340"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="11">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="11">
        <location>
            <begin position="267"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN57184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW25844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="468" mass="51272" checksum="240A2C9DA42A3264" modified="2016-02-17" version="1">MSLHLYNSLSRQVEAFVPLDPARPTMYVCGPTVYNYAHIGNARGPVVFDVLAGLLRRRYGALAYARNITDVDDKINAAAAEQQVPISAITERFAAIYRDDMSALGVRLPDIEPAATAHIGEIVTMIEGLVASGHAYQAEGHVLFSIESYPDYGKLSRRDIDDMRAGARIEVAPYKRDAGDFVLWKPSTGDLPGWDSPWGRGRPGWHIECSAMAAAHLGETIDIHAGGNDLMFPHHENEIAQSECAHGGKTFARFWLHNGMLTFDGEKMAKSRGNIETVHELLAKHPAEALRYALLSAHYRQPLDWSPKLIEQCARTLDRLYGTLRELADVDAGAIAIPAQIEAALNDDLGTPQALAEIARIAAEARKAADPGDKARLKRELLGAGLALGLLQQDPAAWFAGAAGDQDDERIQALVEERTAAKQARDFARADAIRQQLADENILLEDTPQGVRWVRKRPEPQKTEAADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFK9</accession>
    <name>A0A0S2DFK9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2069</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947254.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2069"/>
    <dbReference type="EnsemblBacteria" id="ALN57419">
        <property type="protein sequence ID" value="ALN57419"/>
        <property type="gene ID" value="GLE_2069"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2069"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2034"/>
    <dbReference type="OMA" id="RFERWRP"/>
    <dbReference type="OrthoDB" id="1840839at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="7"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="136"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="371" mass="39601" checksum="188DCE012A694AA9" modified="2016-02-17" version="1">MSEPAPLRVALIGYGFAGKTFHAPLIAATPGLELAVVGSSDAAKVGADLPAVAVVADPLQAATDARAELVVIATPNHSHAPLARAAMAAGKHVVVDKPFTLDLTEARELAALAQRHDRLLSVFQNRRWDSDYLGIKQAVESGRLGAIAHFESHIDRFRPQVRERWREQAGPGTGVWWDLGPHLADQALQLFGPPERVFASLALQREGAVVADWAHVVLEYPRLRAILHAGMLAAGGSPRFLVHGSSGSLLKAHADRQEAQLLAGLTPGAPGWGEDPDPLQWFGPARAEHWPTPAGDQRGYYAAVRDAIRGQGLNPVPPEQAVALMAVLEAAAESAAQGRAIAPDLSEAERAAADEMRLWRAELRASSLAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFZ8</accession>
    <name>A0A0S2DFZ8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HTH-type transcriptional regulator YcaN</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">LysR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ycaN</name>
        <name evidence="4" type="ORF">FE772_11055</name>
        <name evidence="3" type="ORF">GLE_2193</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947354.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2193"/>
    <dbReference type="EnsemblBacteria" id="ALN57542">
        <property type="protein sequence ID" value="ALN57542"/>
        <property type="gene ID" value="GLE_2193"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2193"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2155"/>
    <dbReference type="OMA" id="KRYRWEF"/>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="17"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="313" mass="34446" checksum="9C611CC1604DD702" modified="2016-02-17" version="1">MKSTHQSKGGDLSAYSVFLAVANQRSFRAAAAELDLTPSAISHSIKSLEQRLGIRLFNRTTRSMALTDAGERLLARLRPAMAAIEDAVQEIEERRGTPSGTVRINASEGAIRLVLKPLLARFLREHPQVRLDLVSDGRLSDIVADGFDAGIRLAEAVAQDMVAVTVLDRVRFAALASPAYLAARGRPRVPQDLHGHDCIRFRFESGAIYRWEFERRGSVERINVDGPLTLTDQPLMVEAAIDGIGIAFVPDHLAADALRDGRLQRVLEDWCPDSPGLCLYYPGHRHVSSGLRALIDALSEQRRRWSAQAAAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG26</accession>
    <name>A0A0S2DG26_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Methyltransferase type 12</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_09795</name>
        <name evidence="1" type="ORF">GLE_1921</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947145.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1921"/>
    <dbReference type="EnsemblBacteria" id="ALN57272">
        <property type="protein sequence ID" value="ALN57272"/>
        <property type="gene ID" value="GLE_1921"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1921"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1887"/>
    <dbReference type="OMA" id="WACACLI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="203" mass="22609" checksum="3AEDD17B628108CD" modified="2016-02-17" version="1">MTDADRRNNRRTVAAYEGYARGYAAAVPATPSPQAAADLRRFAASLAPPARVLEIGSGPGWDADFLETLGAQVRRTDVTAAFVRFQIERGKQAYPLDLLSDEIEGTYDGILLLYVVQHFERDQLDEALRKLARALTAQGVALLSHMLGDGDEWEGDAGDYRVVRWPAAAMDERLRRAGFAVEWESFIDSERRPWRSVLARKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGF1</accession>
    <name>A0A0S2DGF1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Copper-translocating P-type ATPase</fullName>
            <ecNumber evidence="13">3.6.3.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLE_2354</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.4" evidence="13"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947474.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2354"/>
    <dbReference type="EnsemblBacteria" id="ALN57703">
        <property type="protein sequence ID" value="ALN57703"/>
        <property type="gene ID" value="GLE_2354"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2354"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2316"/>
    <dbReference type="OMA" id="HWMLPAW"/>
    <dbReference type="OrthoDB" id="237367at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006825">
        <property type="term" value="P:copper ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006122">
        <property type="entry name" value="HMA_Cu_ion-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00003">
        <property type="entry name" value="TIGR00003"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-0187">Copper transport</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="217"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="254"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="431"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="459"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="775"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="798"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="12">
        <location>
            <begin position="13"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="12">
        <location>
            <begin position="80"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="144"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN57703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="824" mass="84672" checksum="22C2E18091D2057F" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGS6</accession>
    <name>A0A0S2DGS6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_11550</name>
        <name evidence="2" type="ORF">GLE_2299</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947432.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2299"/>
    <dbReference type="EnsemblBacteria" id="ALN57648">
        <property type="protein sequence ID" value="ALN57648"/>
        <property type="gene ID" value="GLE_2299"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2299"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2264"/>
    <dbReference type="OrthoDB" id="1701844at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242665" evidence="1">
        <location>
            <begin position="25"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="184" mass="20087" checksum="FBFDDB14100510C5" modified="2016-02-17" version="1">MNRSLSRFASVAVSALVLPLAASAAEAPYRDAAQVRAELAKIVTCEATREEFMRMGSALTPLYYDKPEEVQPALAGWRNAKDANTFVAIFEMPEPIKVYGHSTKQVMMAGEGLLAVIDGDVADALSKQFKLKPSDEPLAKHIRTRELRREALGDGVDATVTQTVSTLSTHPGKTMVGCEYKMVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH70</accession>
    <name>A0A0S2DH70_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2443</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2443"/>
    <dbReference type="EnsemblBacteria" id="ALN57792">
        <property type="protein sequence ID" value="ALN57792"/>
        <property type="gene ID" value="GLE_2443"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2443"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2406"/>
    <dbReference type="OMA" id="SVYSFCM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028348">
        <property type="entry name" value="FAD-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42842">
        <property type="entry name" value="PTHR42842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038984">
        <property type="entry name" value="FAD_binding_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="1">
        <location>
            <begin position="225"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="560" mass="60525" checksum="E2F1A212F4F5CA3A" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH92</accession>
    <name>A0A0S2DH92_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Inner membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_02390</name>
        <name evidence="3" type="ORF">GLE_2424</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">B25</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000004">
        <property type="protein sequence ID" value="OPD65627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947528.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2424"/>
    <dbReference type="EnsemblBacteria" id="ALN57773">
        <property type="protein sequence ID" value="ALN57773"/>
        <property type="gene ID" value="GLE_2424"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65627">
        <property type="protein sequence ID" value="OPD65627"/>
        <property type="gene ID" value="BV903_02390"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2424"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2386"/>
    <dbReference type="OMA" id="HHWPVFL"/>
    <dbReference type="OrthoDB" id="2047758at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007401">
        <property type="entry name" value="DUF454"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35813">
        <property type="entry name" value="PTHR35813"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04304">
        <property type="entry name" value="DUF454"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016789">
        <property type="entry name" value="DUF454"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR016789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD65627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="129" mass="13829" checksum="EC42806C045C4F13" modified="2016-02-17" version="1">MRWLWFALGWLMLALGAIGALLPVMPTTIFLILAVACFARSSPTFERRLLAHPRYGPALRLWREQGAVTRKGKCFASAGMALGFALFCWGAHPSLTLLLAVGAGFAASAAYVLSRPAPRARPLGSSALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHB1</accession>
    <name>A0A0S2DHB1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_00095</name>
        <name evidence="3" type="ORF">FE772_12945</name>
        <name evidence="1" type="ORF">GLE_2580</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000001">
        <property type="protein sequence ID" value="OPD65952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947652.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000001.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57929">
        <property type="protein sequence ID" value="ALN57929"/>
        <property type="gene ID" value="GLE_2580"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65952">
        <property type="protein sequence ID" value="OPD65952"/>
        <property type="gene ID" value="BV903_00095"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2580"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2539"/>
    <dbReference type="OrthoDB" id="2084750at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD65952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="345" mass="38043" checksum="CAF768942DAFC1B9" modified="2016-02-17" version="1">MSNLSREEFLALNAIAKSRRELMFQTFNGTQLKFGKFSYAKGNWHGMATGIYEFQGMIQEKVTEAMLPKIQEAAQAFAADAAGVGNFNELVAALGQESAGQLLKEIIPWVGLVYTTINWAKASKQVITDAHHLYRIKAGDFRSGFRDGTPQAAVDSVQQIIKRELYVGGIDWANQTVGFGTKVAGVFIDMGTATTLGPGIATFIADWLLKLTVIGMDIKQMKAGNRWLQNPGDLSIKVFEECPILGCYLLISADTSSVANLFVADIGLPNWMTQVEQMYESKIEPTVRYARDLVDRSNLQLEGVSGRAQPAKTHVKKDFFLKSKAKAAKDYLRAHVPHRSSRPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHB2</accession>
    <name>A0A0S2DHB2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 16">Aconitate hydratase B</fullName>
            <ecNumber evidence="5 16">4.2.1.3</ecNumber>
            <ecNumber evidence="6 16">4.2.1.99</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">2-methylisocitrate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="primary">acnB</name>
        <name evidence="23" type="ORF">BV903_01845</name>
        <name evidence="24" type="ORF">FE772_11545</name>
        <name evidence="22" type="ORF">GLE_2298</name>
    </gene>
    <organism evidence="22 25">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="22 25" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 25">C3</strain>
        </source>
    </reference>
    <reference evidence="23 26" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 26">B25</strain>
        </source>
    </reference>
    <reference evidence="24 27" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24 27">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = 2-methyl-cis-aconitate + H2O</text>
            <dbReference type="Rhea" id="RHEA:17941"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57429"/>
            <dbReference type="ChEBI" id="CHEBI:57872"/>
            <dbReference type="EC" id="4.2.1.99"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 16">
            <text>citrate = D-threo-isocitrate</text>
            <dbReference type="Rhea" id="RHEA:10336"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="EC" id="4.2.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="17">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 16">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Organic acid metabolism; propanoate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.3" evidence="5 16"/>
    <dbReference type="EC" id="4.2.1.99" evidence="6 16"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000004">
        <property type="protein sequence ID" value="OPD65538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947431.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2298"/>
    <dbReference type="EnsemblBacteria" id="ALN57647">
        <property type="protein sequence ID" value="ALN57647"/>
        <property type="gene ID" value="GLE_2298"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65538">
        <property type="protein sequence ID" value="OPD65538"/>
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</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
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            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
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                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <location>
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            <position position="167"/>
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        <ligand>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
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    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN57938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1038" mass="110712" checksum="F5236FC5E9749008" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHT4</accession>
    <name>A0A0S2DHT4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methanol dehydrogenase regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2666</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947717.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2666"/>
    <dbReference type="EnsemblBacteria" id="ALN58014">
        <property type="protein sequence ID" value="ALN58014"/>
        <property type="gene ID" value="GLE_2666"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2666"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2625"/>
    <dbReference type="OMA" id="RAGQAMI"/>
    <dbReference type="OrthoDB" id="688156at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_3" evidence="1">
        <location>
            <begin position="49"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_lid_2" evidence="2">
        <location>
            <begin position="260"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="333" mass="36027" checksum="0DC130B336FFE424" modified="2016-02-17" version="1">MSGNDNNGDDALQAQLARLGELRAAIAQAIVGQDEVVEQLLIGLLAGGHCLLEGVPGLGKTLLVRSLGQALELQFRRIQFTPDLMPSDILGTELLEEDHGTGHRHFRFQPGPIFTSLLLADELNRTPPKTQAALLEAMQERTVSYAGTTHSLPAPFFVLATQNPLEQAGTYPLPEAQLDRFLLHIRVGYPSEQEEHDILQQTTGSGGAQVPKVMDAQAVLALQARVREVHLGEDVLRWITRLVRASRPAADALIEVRQWVKWGAGPRAGQSLVLAAKARALLHGRFAATREDIIALAAPVMRHRLLLSFAAEAEGKSADDVIAALLRGVPLPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHU2</accession>
    <name>A0A0S2DHU2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Copper resistance protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">copA</name>
        <name evidence="6" type="ORF">GLE_2628</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947688.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2628"/>
    <dbReference type="EnsemblBacteria" id="ALN57976">
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        <property type="gene ID" value="GLE_2628"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2628"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2587"/>
    <dbReference type="OMA" id="WNQMRMS"/>
    <dbReference type="OrthoDB" id="971126at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13874">
        <property type="entry name" value="CuRO_2_CopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13896">
        <property type="entry name" value="CuRO_3_CopA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="Cu-oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006376">
        <property type="entry name" value="Cu-R_CopA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034282">
        <property type="entry name" value="CuRO_2_CopA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034279">
        <property type="entry name" value="CuRO_3_CopA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="PTHR11709"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01480">
        <property type="entry name" value="copper_res_A"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastocyanin-like" evidence="5">
        <location>
            <begin position="60"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="3">
        <location>
            <begin position="181"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="4">
        <location>
            <begin position="497"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="611" mass="67329" checksum="D8AA567D2A35B49D" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHY7</accession>
    <name>A0A0S2DHY7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF3011 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_12900</name>
        <name evidence="2" type="ORF">GLE_2570</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947644.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2570"/>
    <dbReference type="EnsemblBacteria" id="ALN57919">
        <property type="protein sequence ID" value="ALN57919"/>
        <property type="gene ID" value="GLE_2570"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2570"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2529"/>
    <dbReference type="OMA" id="RCESIKN"/>
    <dbReference type="OrthoDB" id="1739867at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021381">
        <property type="entry name" value="DUF3011"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726729" evidence="1">
        <location>
            <begin position="24"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="178" mass="18943" checksum="B7C563F9D85A8E4D" modified="2016-02-17" version="1">MYVRIASGLALAAGLALCAQAEAAPQYGSHGGYGGGDTIRCESDGGRQRYCQADTRGGVRLSRQLSNSSCVQGSSWGYDRRGVWVSQGCRADFEIGRGGRGGSGWGQSGAGWGDRGGGQVLSCDSNKERLNRCNASVRRGARLVRQNSNSPCIEGQSWGWDRNGVWVSNGCRGQFRID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI35</accession>
    <name>A0A0S2DI35_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YiaA/B two helix domain family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_13585</name>
        <name evidence="3" type="ORF">GLE_2713</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947759.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58061">
        <property type="protein sequence ID" value="ALN58061"/>
        <property type="gene ID" value="GLE_2713"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2713"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2672"/>
    <dbReference type="OMA" id="GFYAFAF"/>
    <dbReference type="OrthoDB" id="1733599at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038972">
        <property type="entry name" value="YiaA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008024">
        <property type="entry name" value="YiaAB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37290">
        <property type="entry name" value="PTHR37290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05360">
        <property type="entry name" value="YiaAB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="YiaAB" evidence="2">
        <location>
            <begin position="13"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="YiaAB" evidence="2">
        <location>
            <begin position="77"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="143" mass="15684" checksum="E91618DB709A5E7D" modified="2016-02-17" version="1">MNRAISRKPTAAFVGASWGALLLGSLAYLVGLWNASTMQLNEKGYYLALLLYGLFAAVSVQKSVRDRMEGIPVTNIYYGLAWFSVVTALTLLFVGLWNAELAFSEKGFYAMAYAMSLFAAIAVQKNTRDSGDGGERVEERSFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI43</accession>
    <name>A0A0S2DI43_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_2794</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58142">
        <property type="protein sequence ID" value="ALN58142"/>
        <property type="gene ID" value="GLE_2794"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2794"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2750"/>
    <dbReference type="OMA" id="WFGQPDF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="34"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="213" mass="23268" checksum="37C63666839A3C21" modified="2016-02-17" version="1">MARVDEPVYHRPMPARAAATHNAHNTRRGAAAPQSARERILQTAHDLFSLEGIRATGIDRVIAESGVTKVTLYRHYPSKNELILAFLDYRHERWMAWFDAALRRFGDDAAALAPALAEWFAHPQFRGCAFINTVAELGPALPQAIERAQTHKRAMQARIAALLPAGPARETRARALAVAVDGAIVRAACDGDASDALDALRCMVAATMAKKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI64</accession>
    <name>A0A0S2DI64_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 18">Succinate dehydrogenase flavoprotein subunit</fullName>
            <ecNumber evidence="7 18">1.3.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">sdhA</name>
        <name evidence="22" type="ORF">FE772_15215</name>
        <name evidence="21" type="ORF">GLE_3044</name>
    </gene>
    <organism evidence="21 23">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="21 23" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 23">C3</strain>
        </source>
    </reference>
    <reference evidence="22 24" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 24">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 18">
            <text>a quinone + succinate = a quinol + fumarate</text>
            <dbReference type="Rhea" id="RHEA:40523"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 18">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 18">Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (bacterial route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 18">Cell inner membrane</location>
            <topology evidence="4 18">Peripheral membrane protein</topology>
            <orientation evidence="4 18">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 18">Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.1" evidence="7 18"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3044"/>
    <dbReference type="EnsemblBacteria" id="ALN58391">
        <property type="protein sequence ID" value="ALN58391"/>
        <property type="gene ID" value="GLE_3044"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3044"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3004"/>
    <dbReference type="OMA" id="DPIPIQP"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER01005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008177">
        <property type="term" value="F:succinate dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003952">
        <property type="entry name" value="FRD_SDH_FAD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030664">
        <property type="entry name" value="SdhA/FrdA/AprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011281">
        <property type="entry name" value="Succ_DH_flav_su_fwd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014006">
        <property type="entry name" value="Succ_Dhase_FrdA_Gneg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632">
        <property type="entry name" value="PTHR11632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="SSF46977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="SSF56425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01816">
        <property type="entry name" value="sdhA_forward"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01812">
        <property type="entry name" value="sdhA_frdA_Gneg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00504">
        <property type="entry name" value="FRD_SDH_FAD_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="18" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="18" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13 18" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12 18" id="KW-0274">FAD</keyword>
    <keyword evidence="11 18" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="15 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="14 18" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 18" id="KW-0813">Transport</keyword>
    <keyword evidence="10 18" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="19">
        <location>
            <begin position="13"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="Succ_DH_flav_C" evidence="20">
        <location>
            <begin position="464"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="16">
        <location>
            <position position="291"/>
        </location>
    </feature>
    <feature type="modified residue" description="Tele-8alpha-FAD histidine" evidence="17">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00008040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00019965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR611281-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR611281-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU362051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ALN58391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="QCW26791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="597" mass="64756" checksum="75306477FB39CE87" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIB6</accession>
    <name>A0A0S2DIB6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_13925</name>
        <name evidence="2" type="ORF">GLE_2789</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58137">
        <property type="protein sequence ID" value="ALN58137"/>
        <property type="gene ID" value="GLE_2789"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2789"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2745"/>
    <dbReference type="OMA" id="GPPEAYV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242319" evidence="1">
        <location>
            <begin position="25"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="184" mass="19661" checksum="5D3F5C1E7EE55844" modified="2016-02-17" version="1">MKSARIAALALVVALAACSKPAPAPPAPAAAAPAPAPAASPAAAPAAARPALPEGACAKTEDGFASFLEAFIAEPDKRAAYTSPNFEVREIKAPDQPIAHQTGPTEPFRIALVDYQWSYFEPGKPDGELARIKLDRKLEGDRMRLDFAKAEFSPDDEVVKTLGPPEAYVFQHQQGCWQLTLQLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DID1</accession>
    <name>A0A0S2DID1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Lipopolysaccharide assembly protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 7" type="primary">lapB</name>
        <name evidence="6" type="ORF">BV903_02740</name>
        <name evidence="7" type="ORF">FE772_14575</name>
        <name evidence="5" type="ORF">GLE_2922</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LapB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000005">
        <property type="protein sequence ID" value="OPD65452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947913.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000005.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2922"/>
    <dbReference type="EnsemblBacteria" id="ALN58270">
        <property type="protein sequence ID" value="ALN58270"/>
        <property type="gene ID" value="GLE_2922"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65452">
        <property type="protein sequence ID" value="OPD65452"/>
        <property type="gene ID" value="BV903_02740"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2922"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2884"/>
    <dbReference type="OMA" id="FWQCPGC"/>
    <dbReference type="OrthoDB" id="1425742at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031235">
        <property type="term" value="C:intrinsic component of the cytoplasmic side of the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008653">
        <property type="term" value="P:lipopolysaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046890">
        <property type="term" value="P:regulation of lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00994">
        <property type="entry name" value="LPS_assembly_LapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030865">
        <property type="entry name" value="LapB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041166">
        <property type="entry name" value="Rubredoxin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18073">
        <property type="entry name" value="Rubredoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="2">
        <location>
            <begin position="26"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="Rubredoxin_2" evidence="4">
        <location>
            <begin position="358"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="360"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="363"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="374"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="377"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF18073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD65452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW26695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="392" mass="43843" checksum="00B888DFF200CC4B" modified="2016-02-17" version="1">MEFISQWFWFFLLLPIAALSGWVIGRRGGERHSDNQVSHLSTTYFRGLNYLLNEQPDKAIELFLHIAELDKDTFETQVALGHLFRRRGEVDRAIRLHQALVQRPGLSDQQKVQALLALGEDYMRSGLLDRAETVFSDLVALDMRAPLALRHLIGIYQAERDWGKAIENAQRFEAATGEPMGKLIAQFECELADRHRAAGDAQGAREAVKRAYEADANSVRAGMLEGRIEVEAGNDTAAIRAFERVARADPDYLPEVLPALLSCYERNGDPTGARAFLAEMCEHYRGISPVLALTRMVEAEDGVPAARAYLARQLKDRPSVRGEAALIDLTLAEGADPLATLHDLKHITDQLLVRNPSYRCNRCGFGARSHHWQCPSCKEWGTVKPLLNYAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIF6</accession>
    <name>A0A0S2DIF6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">EF hand domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_02920</name>
        <name evidence="4" type="ORF">FE772_14835</name>
        <name evidence="2" type="ORF">GLE_2966</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000005">
        <property type="protein sequence ID" value="OPD65486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947945.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000005.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2966"/>
    <dbReference type="EnsemblBacteria" id="ALN58314">
        <property type="protein sequence ID" value="ALN58314"/>
        <property type="gene ID" value="GLE_2966"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65486">
        <property type="protein sequence ID" value="OPD65486"/>
        <property type="gene ID" value="BV903_02920"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2966"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2927"/>
    <dbReference type="OMA" id="KCGDASF"/>
    <dbReference type="OrthoDB" id="1732109at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="SSF47473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="1">
        <location>
            <begin position="66"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="1">
        <location>
            <begin position="93"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD65486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="138" mass="14016" checksum="F51F960412D1DE9F" modified="2016-02-17" version="1">MSRNPTTARPVRTLGLLGVALGGGLLLAGQAFASQPLAQGYLVSAGHAAKAAEGKCGEGKCGEESFAKTDANHDGKVSREEFVARAPDRAAEFDAIDKNHDGAISLPEALESVKAARKAAGKPVGEGKCGEGKCGGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIF8</accession>
    <name>A0A0S2DIF8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">LytTR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LytR/AlgR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_15375</name>
        <name evidence="3" type="ORF">GLE_3080</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3080"/>
    <dbReference type="EnsemblBacteria" id="ALN58427">
        <property type="protein sequence ID" value="ALN58427"/>
        <property type="gene ID" value="GLE_3080"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3080"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3039"/>
    <dbReference type="OMA" id="TADIEWI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012379">
        <property type="entry name" value="LytTR_MHYE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF031767">
        <property type="entry name" value="MHYE_LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="2">
        <location>
            <begin position="202"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="307" mass="34534" checksum="B15B6E3F37320398" modified="2016-02-17" version="1">MNADASAALAAVPPATAVEPERGAWDRYRPWRRPVEIAFWVALFAINAAAGTLTSIIDIHRYGLDIPDWAPLVWETSSCATALALVPALVWFTRAVPLQLDGWRRTLALHLLASVVWSVLHVVGMVAIRQAVYASVGERYELGGWGINLVYEYLKDARSYGYMVLWIEGYRLLLRRLQGEASVLAPPDDLPEPAQPERPERFLVRKLGKEFLVAANEVEWLQASSNYVNLRVRGRDYPLRSTMAAIEGQLDPGRFARVHRSYIVNLDCVGEIEPLESGDARITMRDGSHVPCSRRYRAALRRDRRTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIS0</accession>
    <name>A0A0S2DIS0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Epoxyqueuosine reductase</fullName>
            <ecNumber evidence="7">1.17.99.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Queuosine biosynthesis protein QueG</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">queG</name>
        <name evidence="9" type="ORF">GLE_3171</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>AH2 + epoxyqueuosine(34) in tRNA = A + H2O + queuosine(34) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:32159"/>
            <dbReference type="Rhea" id="RHEA-COMP:10345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10346"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:82831"/>
            <dbReference type="ChEBI" id="CHEBI:82834"/>
            <dbReference type="EC" id="1.17.99.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="7">Binds 2 [4Fe-4S] clusters per monomer.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the QueG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.17.99.6" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3171"/>
    <dbReference type="EnsemblBacteria" id="ALN58517">
        <property type="protein sequence ID" value="ALN58517"/>
        <property type="gene ID" value="GLE_3171"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3171"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3126"/>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052693">
        <property type="term" value="F:epoxyqueuosine reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00916">
        <property type="entry name" value="QueG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004453">
        <property type="entry name" value="QueG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013542">
        <property type="entry name" value="QueG_DUF1730"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30002">
        <property type="entry name" value="PTHR30002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08331">
        <property type="entry name" value="DUF1730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00276">
        <property type="entry name" value="TIGR00276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="7" id="KW-0170">Cobalt</keyword>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 7" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="207"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Cob(II)alamin binding" evidence="7">
        <location>
            <begin position="272"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN58517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="396" mass="44494" checksum="D7FDF87ED4E3EC7C" modified="2016-02-17" version="1">MPGFYTCRIVSQIDASPSSPLPGPAGRPAPDYAALARRIRALAREFGFQRCGISGVELGEDEAYLLDWLERGLHGSMDWMARHGELRARPAQLLPGTVRVISVGLDYGRRDDEEAWATLADGERAYVARYALGRDYHKLMRQRLQRLAERLAELVGPFGHRVFVDSAPVLERALARNAGLGWIGKHTCLIDKDGGSWFFLGEIYVDLPLPVDAPASAHCGTCVRCIDVCPTQAIVAPHRLDARRCIAYLTIEHDGAIPLELREPIGNRIFGCDDCQLVCPWNKFAKRSDEPDFRARNDLDRATLAQLFAWEEDEFLRRTEGSAIRRSGHERWLRNIAVALGNAPTTPEAIAALRSRLQHPSELVREHVQWALAKHXXXXXXXRSYRVFGRKRRTAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIS8</accession>
    <name>A0A0S2DIS8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PhoH family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Phosphate starvation-inducible protein PhoH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BV903_09345</name>
        <name evidence="7" type="ORF">FE772_15830</name>
        <name evidence="5" type="ORF">GLE_3187</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhoH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000020">
        <property type="protein sequence ID" value="OPD64238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948108.1">
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_3187"/>
    <dbReference type="EnsemblBacteria" id="ALN58533">
        <property type="protein sequence ID" value="ALN58533"/>
        <property type="gene ID" value="GLE_3187"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64238">
        <property type="protein sequence ID" value="OPD64238"/>
        <property type="gene ID" value="BV903_09345"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3187"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3141"/>
    <dbReference type="OMA" id="KMSPWAQ"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003714">
        <property type="entry name" value="PhoH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02562">
        <property type="entry name" value="PhoH"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PIN_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="4">
        <location>
            <begin position="6"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD64238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW26892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="465" mass="52081" checksum="FDBB248332C8CC7D" modified="2016-02-17" version="1">MTRSKRIYVLDTNVLMHDPTALFKFEEHDVYLPMQVIEELDNGKKGTSEASRNARQVSRFLNELIEAEGTDKISSGISLVRPQGLQLRGAQSIGKLRFQTDSFDAGKRFGTVIPDNHILGAVLALKESDPGAPVVLVSKDINLRIKASIAGIVSEDYENDRALDDFSLLYTGATALPEDFWQRHGKDLKSWTEKGRTFYEIGRTDNDDWYPNQFLYLPGDDESELKVTKVGEERVTLQIVDDFRHHQHSVWGIAARNREQNFALNALMDPEIDFVTLLGTAGTGKTLLALAAGLAQTMDQQRYREIIMTRATVSVGEDIGFLPGTEEEKMTPWMGALTDNLEVLTHNQDGGAWGRAATNDLLASRIKIRSMNFMRGRTFLSRWLILDEAQNLTPKQMKTLITRAGPGTKIVCLGNVEQIDTPYLTETTSGLTYAVDRFKGWAHSAHVTLRRGERSRLADYASEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIU2</accession>
    <name>A0A0S2DIU2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_15400</name>
        <name evidence="2" type="ORF">GLE_3088</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948032.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58435">
        <property type="protein sequence ID" value="ALN58435"/>
        <property type="gene ID" value="GLE_3088"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3088"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3047"/>
    <dbReference type="OrthoDB" id="1467120at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="14"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="137" mass="14919" checksum="CB8BA618057C2516" modified="2016-02-17" version="1">MNQSSQGGAGAPAAQAFVPMIHVASVARSIGFYELLGFAVGNVHRVPECGDEPVWAWMQSPAGAQMMLVRADGPVDDGVQAVLFYVYCDDVDGMRERVRAAGFEAGPMGYPFYRPRGEFRSRDPDGYVLMITHSQDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ11</accession>
    <name>A0A0S2DJ11_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Extracellular protease</fullName>
            <ecNumber evidence="9">3.4.24.-</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="10">Protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">eprA1</name>
        <name evidence="10" type="ORF">FE772_15305</name>
        <name evidence="9" type="ORF">GLE_3062</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948015.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3062"/>
    <dbReference type="EnsemblBacteria" id="ALN58409">
        <property type="protein sequence ID" value="ALN58409"/>
        <property type="gene ID" value="GLE_3062"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3062"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3022"/>
    <dbReference type="OMA" id="RYNTWFG"/>
    <dbReference type="OrthoDB" id="1316225at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11306">
        <property type="entry name" value="M35_peptidyl-Lys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029463">
        <property type="entry name" value="Lys_MEP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034115">
        <property type="entry name" value="M35_peptidyl-Lys"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14521">
        <property type="entry name" value="Aspzincin_M35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01351">
        <property type="entry name" value="Aspzincin_M35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 9" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242573" evidence="7">
        <location>
            <begin position="21"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="Aspzincin_M35" evidence="8">
        <location>
            <begin position="229"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN58409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW26805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="368" mass="38954" checksum="67B464763D024973" modified="2016-02-17" version="1">MKLRIVHVVSVGAVLSGAIAAAVATPPSATQNNPLRIGMVAVTGNADDFLGAVEVSVTNTSKKAVRLPKWQLPSDEFDAKLFSISYNGEAVAYEGKMVKRGLPSAADFAILQPGETVRRIVDLSAGYDLSRTGQYVVTFRAPLQHASTSDRVMLHQANGLPMSAQSAPLQLWVDGIDQLGGAKVAAAKKPVGPTAVVNGVNYVGCTTARTSSAGQAVVQARAYSENAKGYLNAGTVGPRYTTWFGAYTASRYSTARSHFQAIDAALDQNNGQITINCGCTSSAYAYVYANQPYQIYVCNAFWNAPLTGTDSKAGTLVHEMSHFTVVAGTDDHAYGQAAAKNLATSNPTNALDNADNHEYFAENTPFQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJH6</accession>
    <name>A0A0S2DJH6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58656">
        <property type="protein sequence ID" value="ALN58656"/>
        <property type="gene ID" value="GLE_3310"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3310"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3260"/>
    <dbReference type="OMA" id="WAARERY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="160" mass="16554" checksum="90490486AFF11717" modified="2016-02-17" version="1">MSERAPNACVCACADASGARAHAIARALADDDLDRAIALGLLDPDFDAACVCTACAPACAQRSRDARQARLRALAARERYRARDRRLQRRAEERTAQRAAASVRTAAETSADDTAADAATASTASPNLPAAETAPRRALPSAAAAALARAKAKAAQRGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJI1</accession>
    <name>A0A0S2DJI1_LYSEN</name>
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        <submittedName>
            <fullName evidence="14">Hemagglutinin</fullName>
        </submittedName>
    </protein>
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        <name evidence="15" type="ORF">FE772_15415</name>
        <name evidence="14" type="ORF">GLE_3093</name>
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    <organism evidence="14 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">C3</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell surface</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948035.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3093"/>
    <dbReference type="EnsemblBacteria" id="ALN58440">
        <property type="protein sequence ID" value="ALN58440"/>
        <property type="gene ID" value="GLE_3093"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3093"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3051"/>
    <dbReference type="OMA" id="FNAGGTF"/>
    <dbReference type="OrthoDB" id="1211448at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008635">
        <property type="entry name" value="Coiled_stalk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005594">
        <property type="entry name" value="YadA_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03895">
        <property type="entry name" value="YadA_anchor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05662">
        <property type="entry name" value="YadA_stalk"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101967">
        <property type="entry name" value="SSF101967"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726731" evidence="11">
        <location>
            <begin position="50"/>
            <end position="1323"/>
        </location>
    </feature>
    <feature type="domain" description="YadA_stalk" evidence="13">
        <location>
            <begin position="361"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="YadA_stalk" evidence="13">
        <location>
            <begin position="630"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="domain" description="YadA_stalk" evidence="13">
        <location>
            <begin position="735"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="domain" description="YadA_stalk" evidence="13">
        <location>
            <begin position="838"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="domain" description="YadA_stalk" evidence="13">
        <location>
            <begin position="943"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="domain" description="YadA_stalk" evidence="13">
        <location>
            <begin position="1145"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="domain" description="YadA_stalk" evidence="13">
        <location>
            <begin position="1200"/>
            <end position="1232"/>
        </location>
    </feature>
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        <location>
            <begin position="1263"/>
            <end position="1323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF05662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN58440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW26823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="1323" mass="129527" checksum="28F6C74A176A60E0" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJI7</accession>
    <name>A0A0S2DJI7_LYSEN</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3346</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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        </lineage>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58692">
        <property type="protein sequence ID" value="ALN58692"/>
        <property type="gene ID" value="GLE_3346"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3346"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3296"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="53" mass="5647" checksum="FAC4AD3EFB53CDBD" modified="2016-02-17" version="1">MPRRRRAVHVHRTNRAGWGHSLAGTGTRRCARAPHAALPVATLASAPGVRGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJM9</accession>
    <name>A0A0S2DJM9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ALN58746">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="387" mass="41075" checksum="7081895561D35BE3" modified="2016-02-17" version="1">MAHEETMSALERQRRGLLAAFGASALLTLFPRVAAAGASDTRLLLVLLRGGLDGLHLLPPYAEPAYAGLRRDGAVADPIRIDGLFGLHPAMRQSAAMYRAGQLLPLVAVAPPYRQRSHFDAQDCLENGTATPNGARDGWLGRCVRAMSGGQALAVAAVMPLALRGGSDRVSNWWPPLPRPVDPQLLQQLQPLYAADPRLSETFERSAGSGGMPRDGKGAFALPEAMRVAAQRMSAADGPRIGFVEDSGWDSHRNQAPQLQRKLAELDQGLAAAREGFGAAWPRTVVAVVTEFGRTAALNGTDGTDHGTGGMALLCGGAVRGGRIGGDWPGLGPSQLNEGRDLRATTDLRAVFKSVLVEHLGLTDAAVERSVFPDSRGLPPLRDWLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJN1</accession>
    <name>A0A0S2DJN1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3388</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58734">
        <property type="protein sequence ID" value="ALN58734"/>
        <property type="gene ID" value="GLE_3388"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3388"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="58" mass="5833" checksum="744649A0D2307C9E" modified="2016-02-17" version="1">MQVEMNEGSGHAYRFCGRAGGSSCRASRALAAGARDGSRHGGESAGLQGISPAPWGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-06-17" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJP8</accession>
    <name>A0A0S2DJP8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF615 domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">UPF0307 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_16785</name>
        <name evidence="1" type="ORF">GLE_3404</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948270.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58750">
        <property type="protein sequence ID" value="ALN58750"/>
        <property type="gene ID" value="GLE_3404"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3404"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3353"/>
    <dbReference type="OrthoDB" id="1711519at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.60.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023153">
        <property type="entry name" value="PSPTO4464-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006839">
        <property type="entry name" value="Ribosome-assoc_YjgA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04751">
        <property type="entry name" value="DUF615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158710">
        <property type="entry name" value="SSF158710"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="77" mass="9237" checksum="B8CB45487F1D679D" modified="2016-02-17" version="1">MTIDPQLLRIETWRTRLIDQGFDGIEAFAAAYPRADRKRLKRLIQEAASMRHRHRMPRKLLRYIRELDEAANAHPQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJS4</accession>
    <name>A0A0S2DJS4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_3449</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3449"/>
    <dbReference type="EnsemblBacteria" id="ALN58794">
        <property type="protein sequence ID" value="ALN58794"/>
        <property type="gene ID" value="GLE_3449"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3449"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3397"/>
    <dbReference type="OMA" id="FENAAEM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="304"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="21"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="673" mass="72694" checksum="522922C752C38EEA" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJY7</accession>
    <name>A0A0S2DJY7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TetR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">TetR/AcrR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BV903_24240</name>
        <name evidence="6" type="ORF">FE772_17780</name>
        <name evidence="4" type="ORF">GLE_3611</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">C3</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000092">
        <property type="protein sequence ID" value="OPD61314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948415.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000092.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3611"/>
    <dbReference type="EnsemblBacteria" id="ALN58955">
        <property type="protein sequence ID" value="ALN58955"/>
        <property type="gene ID" value="GLE_3611"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61314">
        <property type="protein sequence ID" value="OPD61314"/>
        <property type="gene ID" value="BV903_24240"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3611"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3555"/>
    <dbReference type="OMA" id="PAMLHYY"/>
    <dbReference type="OrthoDB" id="2089619at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041474">
        <property type="entry name" value="NicS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17938">
        <property type="entry name" value="TetR_C_29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="31"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD61314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW27203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="227" mass="24783" checksum="9773D30F3384AC4A" modified="2016-02-17" version="1">MDTPKPARRGRPRKTEAPKRAPGRPAAADNPDLRERLLDAAIACYARQGIAATSLRAIAAEAGVNPALLHYYFGDKEQLQEAVSSERLFPLIVGLREGLADGGDDVFDLVGRFVANMGRIIETHPWLPSLWVREVLCEGGALRQTLLYDKIGPLLPRMLAARFADAQAQGRINADLDPRLLMVSLIGLTLFPAASAPIWRHLFGAEDLDLAAQRRHALALLDKGLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK07</accession>
    <name>A0A0S2DK07_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3606</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58950">
        <property type="protein sequence ID" value="ALN58950"/>
        <property type="gene ID" value="GLE_3606"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3606"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3549"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="39" mass="4210" checksum="8D25EDF028A9073D" modified="2016-02-17" version="1">MSARSPRRAANRRVHAQSAAACALPRRPGASPLRIRRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK53</accession>
    <name>A0A0S2DK53_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DUF5110 domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Glycosyl hydrolase, family 31</fullName>
            <ecNumber evidence="5">3.2.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_17970</name>
        <name evidence="5" type="ORF">GLE_3654</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3654"/>
    <dbReference type="EnsemblBacteria" id="ALN58998">
        <property type="protein sequence ID" value="ALN58998"/>
        <property type="gene ID" value="GLE_3654"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3654"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3598"/>
    <dbReference type="OMA" id="LQWKAFT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032513">
        <property type="entry name" value="AGL_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033403">
        <property type="entry name" value="DUF5110"/>
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        <property type="entry name" value="FA58C"/>
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        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013222">
        <property type="entry name" value="Glyco_hyd_98_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038637">
        <property type="entry name" value="NPCBM_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16338">
        <property type="entry name" value="DUF4968"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DUF5110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08305">
        <property type="entry name" value="NPCBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00776">
        <property type="entry name" value="NPCBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NPCBM" evidence="4">
        <location>
            <begin position="984"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW27237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="1133" mass="123637" checksum="4B8B68DD33C2B014" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKL6</accession>
    <name>A0A0S2DKL6_LYSEN</name>
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        <submittedName>
            <fullName evidence="8">Peptidase, families S8 and S53/proprotein convertase P-domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BV903_16015</name>
        <name evidence="10" type="ORF">FE772_18940</name>
        <name evidence="8" type="ORF">GLE_3852</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000042">
        <property type="protein sequence ID" value="OPD62898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948596.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000042.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3852"/>
    <dbReference type="EnsemblBacteria" id="ALN59195">
        <property type="protein sequence ID" value="ALN59195"/>
        <property type="gene ID" value="GLE_3852"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62898">
        <property type="protein sequence ID" value="OPD62898"/>
        <property type="gene ID" value="BV903_16015"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3852"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3792"/>
    <dbReference type="OMA" id="DTGYVAH"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002884">
        <property type="entry name" value="P_dom"/>
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        <property type="entry name" value="Peptidase_S8/S53_dom"/>
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        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
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        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034176">
        <property type="entry name" value="Peptidases_S8_13"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01483">
        <property type="entry name" value="P_proprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P_HOMO_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
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        <location>
            <begin position="32"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="P/Homo B" evidence="7">
        <location>
            <begin position="474"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD62898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="592" mass="60108" checksum="835FAE1644A1FCE4" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKQ0</accession>
    <name>A0A0S2DKQ0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3519</name>
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    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58863">
        <property type="protein sequence ID" value="ALN58863"/>
        <property type="gene ID" value="GLE_3519"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3519"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3463"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="38" mass="3593" checksum="0333ABD9B9D65CB6" modified="2016-02-17" version="1">MSGRVVSAPAETARAASAPTAIAPAARLTVAADAAELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLF4</accession>
    <name>A0A0S2DLF4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59347">
        <property type="protein sequence ID" value="ALN59347"/>
        <property type="gene ID" value="GLE_4005"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4005"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3942"/>
    <dbReference type="OMA" id="ECECAVT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="25"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="180" mass="19826" checksum="74CAD64810CD1182" modified="2016-02-17" version="1">MNEVHGVVPTSMPQWSQTLRDGSRVRIRPIASADRESERAFIAGLSDESRRHRFLGQISAPSERMLDCLVNIDPIHDAGLVAVTCEADAERIVGAARFSSDPDAVNCECAVVVADQWQGQGLGTALMRHLIDIARARGIERMYSVDMAENADMRELAMYLGFRVRAEPGDASLVVYELPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLG4</accession>
    <name>A0A0S2DLG4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Tyrosine recombinase XerD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11 15" type="primary">xerD</name>
        <name evidence="15" type="ORF">GLE_4189</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the 'phage' integrase family. XerD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4189"/>
    <dbReference type="EnsemblBacteria" id="ALN59531">
        <property type="protein sequence ID" value="ALN59531"/>
        <property type="gene ID" value="GLE_4189"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4189"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4131"/>
    <dbReference type="OMA" id="QAFWYLI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009037">
        <property type="term" value="F:tyrosine-based site-specific recombinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01808">
        <property type="entry name" value="Recomb_XerC_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01807">
        <property type="entry name" value="Recomb_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011932">
        <property type="entry name" value="Recomb_XerD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023009">
        <property type="entry name" value="Tyrosine_recombinase_XerC/XerD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02899">
        <property type="entry name" value="Phage_int_SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02225">
        <property type="entry name" value="recomb_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="6 11" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="4 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0229">DNA integration</keyword>
    <keyword evidence="9 11" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="8 11 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="14">
        <location>
            <begin position="8"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="13">
        <location>
            <begin position="112"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <feature type="active site" description="O-(3'-phospho-DNA)-tyrosine intermediate" evidence="11">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ALN59531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="302" mass="33590" checksum="AE3A3698E7388B88" modified="2016-02-17" version="1">MALPPLEPADADAIASFLDAIWAESGLAQQTLHSYRRDLEGLARWREGRGLAGADRAALFDYLAWRTREGYSPRSNARLLSALRAFYAYRLRRGLRRDDPTALLAPPKLPRSLPKALAESQIDALLAAPEVEQPLGLRDRAMLELMYACGLRVSELVQLPATAINLRQGVLRVMGKGSKERLVPLGEEAQHWLERYLAQARPTLAGKRALAPLFIEPSGEAPSRQAFWHLVKRYAAAAGIDPERISPHGLRHSFATHLLNRGADLRALQLLLGHSSLSTTQIYTLVAREQLKRLHAKHHPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLW6</accession>
    <name>A0A0S2DLW6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">50S ribosomal protein L1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">rplA</name>
        <name evidence="11" type="ORF">BV903_21090</name>
        <name evidence="13" type="ORF">D9T17_09380</name>
        <name evidence="12" type="ORF">FE772_18700</name>
        <name evidence="10" type="ORF">GLE_3800</name>
    </gene>
    <organism evidence="10 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 14">C3</strain>
        </source>
    </reference>
    <reference evidence="11 15" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 15">B25</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">OH11</strain>
        </source>
    </reference>
    <reference evidence="12 17" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.</text>
    </comment>
    <comment type="function">
        <text evidence="8">Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 9">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000067">
        <property type="protein sequence ID" value="OPD61937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000023">
        <property type="protein sequence ID" value="ROU07173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948564.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3800"/>
    <dbReference type="EnsemblBacteria" id="ALN59144">
        <property type="protein sequence ID" value="ALN59144"/>
        <property type="gene ID" value="GLE_3800"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61937">
        <property type="protein sequence ID" value="OPD61937"/>
        <property type="gene ID" value="BV903_21090"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3800"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3744"/>
    <dbReference type="OMA" id="GWTDVDV"/>
    <dbReference type="OrthoDB" id="1671455at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01318_B">
        <property type="entry name" value="Ribosomal_L1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005878">
        <property type="entry name" value="Ribosom_L1_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002143">
        <property type="entry name" value="Ribosomal_L1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_L1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_L1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_L1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023673">
        <property type="entry name" value="Ribosomal_L1_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002155">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="SSF56808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01169">
        <property type="entry name" value="rplA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01199">
        <property type="entry name" value="RIBOSOMAL_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0678">Repressor</keyword>
    <keyword evidence="7 8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 8 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="8" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OPD61937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW27371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROU07173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="232" mass="24162" checksum="1C5FE5A965F0AB77" modified="2016-02-17" version="1">MAMNKREKAIKAAVVPGKAYAFEDAVKIVKTTTKAKFVESVDVAVRLGVDAKKSDQQVRGSTVLPAGTGKTVRVAVFAPAGAKADEALAAGAEAVGMDDLAEKMQAGDLNYDVVIATPDAMRVVGKLGQVLGPRGLMPNPKVGTVSPNPAEAVKNAKGGQVRYRTDKAGIIHCTIGKVSFEDGSLKDNLQALLMDLIKAKPSTSKGQYLQKVSISSTMGPGVIVDQASLTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM17</accession>
    <name>A0A0S2DM17_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Electron transfer flavoprotein-ubiquinone oxidoreductase</fullName>
            <shortName evidence="10">ETF-QO</shortName>
            <ecNumber evidence="10">1.5.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLE_4223</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">Accepts electrons from ETF and reduces ubiquinone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a ubiquinone + reduced [electron-transfer flavoprotein] = a ubiquinol + H(+) + oxidized [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:24052"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="1.5.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="10">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <dbReference type="EC" id="1.5.5.1" evidence="10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4223"/>
    <dbReference type="EnsemblBacteria" id="ALN59564">
        <property type="protein sequence ID" value="ALN59564"/>
        <property type="gene ID" value="GLE_4223"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4223"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4165"/>
    <dbReference type="OMA" id="GGGWMYH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004174">
        <property type="term" value="F:electron-transferring-flavoprotein dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040156">
        <property type="entry name" value="ETF-QO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10617">
        <property type="entry name" value="PTHR10617"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 10" id="KW-0274">FAD</keyword>
    <keyword evidence="4 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <keyword evidence="9 10 13" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="12">
        <location>
            <begin position="491"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="12">
        <location>
            <begin position="531"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="11"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN59564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="571" mass="61559" checksum="D881937C069548AA" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMG9</accession>
    <name>A0A0S2DMG9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_23210</name>
        <name evidence="3" type="ORF">GLE_4343</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000079">
        <property type="protein sequence ID" value="OPD61531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948978.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4343"/>
    <dbReference type="EnsemblBacteria" id="ALN59684">
        <property type="protein sequence ID" value="ALN59684"/>
        <property type="gene ID" value="GLE_4343"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61531">
        <property type="protein sequence ID" value="OPD61531"/>
        <property type="gene ID" value="BV903_23210"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4343"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4282"/>
    <dbReference type="OrthoDB" id="1868160at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595265" evidence="2">
        <location>
            <begin position="25"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD61531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="112" mass="12795" checksum="FB66D7F74BF7532F" modified="2016-02-17" version="1">MHIRSARVPSLLLVASLAAGNAWAQHDGERWRGHDRREGQQQTLSDSVRRFEKESGGGQVLSAERVPFDGRDVNRVKVVDSSGRVRVYMDDPQQRGRRDDDRPTRRDDNNND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMI7</accession>
    <name>A0A0S2DMI7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4497</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59838">
        <property type="protein sequence ID" value="ALN59838"/>
        <property type="gene ID" value="GLE_4497"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4497"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="51" mass="5647" checksum="260FA54B0B1DC0E3" modified="2016-02-17" version="1">MPQPAGPEPQRTRVERDLPPVRAAGFCFIFPYPCGHAEPVAAITARNPPYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMQ9</accession>
    <name>A0A0S2DMQ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4718</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60059">
        <property type="protein sequence ID" value="ALN60059"/>
        <property type="gene ID" value="GLE_4718"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4718"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4652"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="79" mass="8774" checksum="B9EA69CBDB756576" modified="2016-02-17" version="1">MKHSSAPPPREAALRSRSRQVLVLVLVLVLPQLLQLLFAVTQPRPRPTSPSPGGRAHGCARAPWDRMSLMAQPRARCWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN56</accession>
    <name>A0A0S2DN56_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4584</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4584"/>
    <dbReference type="EnsemblBacteria" id="ALN59925">
        <property type="protein sequence ID" value="ALN59925"/>
        <property type="gene ID" value="GLE_4584"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4584"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4520"/>
    <dbReference type="OMA" id="FIQGNSP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018707">
        <property type="entry name" value="LpxR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037107">
        <property type="entry name" value="Put_OMP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09982">
        <property type="entry name" value="DUF2219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595493" evidence="1">
        <location>
            <begin position="20"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="349" mass="38925" checksum="F77DAAD44E91E436" modified="2016-02-17" version="1">MLLSLLFAGTALHAGAAAAQGREACTNGHTRLPPTVNLRLDNDLFGGQDQGYSNGIQLTLVSPNLADYTDDPCIPRLARWINRRLDALQPPQGYEQRNMIATFSQGIFTPTDYSRRDLIRDDRPYAGALLVGLGYNARTGDYLRTTQLQVGIVGPSALGKQVQNAVHRALGDETFQGWDNQLHDEPVFRIVHERMRRFAPKDAHERRWGWDAIGHYGGSFGNLATYANAGMEVRFGLRLPDDFGSTPLRPAGENTAPTEHYNTGDRPFAAHLFLTSDARWVLRDITLDGNTFRASHSVDKRPFVAEVGYGVALMRGRWKFALARYHSTREFEGQKQTPVFGSFTVSRAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNA9</accession>
    <name>A0A0S2DNA9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Band 7 protein family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Slipin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_22785</name>
        <name evidence="3" type="ORF">GLE_4679</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949231.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4679"/>
    <dbReference type="EnsemblBacteria" id="ALN60020">
        <property type="protein sequence ID" value="ALN60020"/>
        <property type="gene ID" value="GLE_4679"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4679"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4615"/>
    <dbReference type="OMA" id="RLYWKGQ"/>
    <dbReference type="OrthoDB" id="809470at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043202">
        <property type="entry name" value="Band-7_stomatin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264">
        <property type="entry name" value="PTHR10264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHB" evidence="2">
        <location>
            <begin position="142"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="376" mass="41238" checksum="05422B4C0B6BC491" modified="2016-02-17" version="1">MFWTKKVVVGDAERVLVYRNRRIERVLGPGVHRLRDLRDELTLDHCNIGNSAYAGNDSEALIAGLGERLSEYFVLADIGNDEVGLVLRNGRYAEVLAPGLRRLYWKGLATIEVRALRLGEGLEIEREVADGLRQIAQLDRVAAHGTVPTESAGLLFVDGKFVRVLAPGAYAFWNLRKNVAVETVELRVQAMEVSGQELLTRDKVTLRVNLAASVRVASPVAARTKVAKYAEHVYRELQYGLRKAVSSKTLDELLGDKASLDADILASARGACAEIGVDVLGVGVKDVILPGEMKEILNAVVQAEKTAQANTIRRREEANATRSLLNTAKLIEDSPVLMRLKELEALEKITEKIDKLTVFGGLEGVMKQLVSLKGHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNG0</accession>
    <name>A0A0S2DNG0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arylamine N-acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4735</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the arylamine N-acetyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.5" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4735"/>
    <dbReference type="EnsemblBacteria" id="ALN60076">
        <property type="protein sequence ID" value="ALN60076"/>
        <property type="gene ID" value="GLE_4735"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4735"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4669"/>
    <dbReference type="OMA" id="CYEHNTL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004060">
        <property type="term" value="F:arylamine N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001447">
        <property type="entry name" value="Arylamine_N-AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11786">
        <property type="entry name" value="PTHR11786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00797">
        <property type="entry name" value="Acetyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01543">
        <property type="entry name" value="ANATRNSFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="309" mass="34013" checksum="79D0B3A80CE35C1C" modified="2016-02-17" version="1">MARSAASVAFIGLTSSAVEGLPWPYPITGRPAMSPRLHDLSRYLQRLGFDAPPPPTLATLAALQQRHSAQFVFETVANLTRAPIALDLDALQRKLLHDGRGGYCYELNGLFQALLRELGFDLRAVAGRVVMGGPEDALTARTHLVALVRLDGADYLADVGFGGMVPTAPLRLDSREPQATPHEPYRLDLRDDGYLLRAEVGGQWRALYVFDLQPLAPIDLEVGNWYVSAHPASPFRDQLLVARTGPGWRKTLNNASFAVHRLGQDSVRRELDGPRAVMEVLEREFGLRLPPGPDVERALARKFEAATRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNH8</accession>
    <name>A0A0S2DNH8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Flagellar motor switch protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fliN</name>
        <name evidence="3" type="ORF">GLE_4646</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FliN/MopA/SpaO family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949210.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4646"/>
    <dbReference type="EnsemblBacteria" id="ALN59987">
        <property type="protein sequence ID" value="ALN59987"/>
        <property type="gene ID" value="GLE_4646"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4646"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4582"/>
    <dbReference type="OMA" id="KTHEPID"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001543">
        <property type="entry name" value="FliN-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001172">
        <property type="entry name" value="FliN_T3SS_HrcQb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036429">
        <property type="entry name" value="SpoA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01052">
        <property type="entry name" value="FliMN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00956">
        <property type="entry name" value="FLGMOTORFLIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101801">
        <property type="entry name" value="SSF101801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FliMN_C" evidence="2">
        <location>
            <begin position="42"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="113" mass="12059" checksum="6CB4E1D10206CCCC" modified="2016-02-17" version="1">MNTPLGVSKIDIMQIDLPEHAAPAAERAAAEPSGQRIPLDMLGEIAVEVEIQLGTARLTVKELMALQAGSLLTLDQHLLQDVDVLLNERVVARGEVVAVGDRFGVRIKELGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNK5</accession>
    <name>A0A0S2DNK5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Flagellum-specific ATP synthase</fullName>
            <ecNumber evidence="5">3.6.3.14</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="6">FliI/YscN family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">fliI</name>
        <name evidence="6" type="ORF">FE772_22620</name>
        <name evidence="5" type="ORF">GLE_4640</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
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    <dbReference type="STRING" id="69.GLE_4640"/>
    <dbReference type="EnsemblBacteria" id="ALN59981">
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        <location>
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        <source>
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    <sequence length="442" mass="46166" checksum="A5B11328E72E4284" modified="2016-02-17" version="1">MALRALLDAIGRVDTATRLGTVTRIMPTFIEADGPGLPLGSLCRVRAGGGQELLAEVAKVETGRITLAPYGAVSGAHVGDSVEALRVGATLPVGPGYLGRIVDPMGAPLDGGGAIGDCERDWPLAGAATSALDRLSPRAPLHSGLRAIDALLTLGVGQRAGIFAGSGVGKTTLLADLAGQVQADVCVLCLVGERGREADDFWRHSLDDAARRRSVMVVASSDQPAILRARSVLAALSLAEYFRAQGKHVLLLLDSITRYALALREIGLAAGEPPTIRAYTPSVFSALPKVIERCGALRQGGAITALMTVLAESDDIDDPMTETLRALLDGHIVLTRALAEQGHYPAIDVPRSISRVFGQVTSSEHRAAAKAAIAQLSLYESSRTLVESGLYAAGTNPELDRALRTRPALLDFLRQDSGQADDAAGSVERLRALLAAGEGSAR</sequence>
</entry>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="312" mass="32387" checksum="0A22BB1B6FF070A6" modified="2016-02-17" version="1">MNLKQALPIAVVSAAIGALAGGAYVRHRDRVEPAPALAAARADAAAAPARDDASGHGGGEAGSPYPRYLALGNGAPASFEALRKRAASDPAFLQDLLQRFRNDPQPDARGELLALLQAVGGEDVLRYALSLAASTRGQDERAGLDLLGGYSLERAEVREALLAKLRAGGDAQREVELIRLLTPAAVADEDAAPVAAQLATLARDPDSEVRAEAVFQLAQWADPVQAEDALHRALLDPAAAVRSKAINAVAGSHARSERLKDALLAIAADPASAPGDRGAAALALQDFRLSRAEYALWKRAQARADAESGEGG</sequence>
</entry>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 3">C3</strain>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
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    </evidence>
    <sequence length="170" mass="17809" checksum="EEE46686619D54E0" modified="2016-02-17" version="1">MHTYIALLRAVNVGGTGKLPMAELRAMCEALGFGEVRTYIASGNVVFRTGLSAAKAKAALEAALHAYAGKPVGAIVRTADEMARALAANPFAQAAPNRAVLIFLDQAPPADALATVRHRKGEELALGEREIYVHYGEGMADSKLAIPAAKAGTARNLNTVVKLIAMAREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </location>
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        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="43" mass="4639" checksum="222D246B087DF037" modified="2016-02-17" version="1">MKTANAKSAAPSPKLAPGQQQKKTQGQGQQFAPRSCSRFIYCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPX7</accession>
    <name>A0A0S2DPX7_LYSEN</name>
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        <submittedName>
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        <name evidence="9" type="ORF">FE772_24995</name>
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    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW28422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_5160"/>
    <dbReference type="EnsemblBacteria" id="ALN60501">
        <property type="protein sequence ID" value="ALN60501"/>
        <property type="gene ID" value="GLE_5160"/>
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        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
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    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
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        </location>
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            <end position="869"/>
        </location>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
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            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
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        </source>
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        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN60501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW28422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="869" mass="94762" checksum="80098197F30C802B" modified="2016-02-17" version="1"> </sequence>
</entry>
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    <accession>A0A0S2DPY1</accession>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="248" mass="26343" checksum="39A97F114943127D" modified="2016-02-17" version="1">MAAAIGCVLAAPAQAQFDAAGQAVLMHQHQVHTGNVLSAEQGALNAGRGRAAPGAVAASSVWSQSLTALARGAASAAAAPDSALRFRRDPALSARVQGEQAGVALKGLSMTPAQMRERFDALLLRYGYARDDLGDVAAAYLAMAWEVANDRNAKDVPGGEAGLRKQLRRALLASPGLRTLSDAQKQELAERLAYAAMRHGVSYEVYRQTGARQELVSLGERVRREVDRQGLDLRRYELVGGQGLSARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
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    </dbReference>
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            <dbReference type="EMBL" id="ALN60312.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="246" mass="25173" checksum="F80C974C4EB1A5E7" modified="2016-02-17" version="1">MSAADTPVRRALVTGGSGDLGGAICLRLAAQGWRVIVHANSGAERAEAVVARIRADGGQAEAVAFDVADGEAARAALERLLQAGPIQGVVNNAGIHDDGPMAGMSDAQWRRVIDVSLHGFFHVTQPLLLPMARTRFGRIVSVSSVAAVLGNRGQSNYAAAKAALHGASKSLAREMASRGITVNVVAPGVVEGRMAAEAFAPEAIKQMVPAGRAGRADEVAAVVAFLCSDDASYVNGQVIGVNGGMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ59</accession>
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    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">GLE_5417</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60758">
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    </dbReference>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="38" mass="4252" checksum="6F226D7109964ABC" modified="2016-02-17" version="1">MRALCHGGRAGDAARARLHRIHFLARAGMWSLAEKHRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ70</accession>
    <name>A0A0S2DQ70_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_5288</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949692.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5288"/>
    <dbReference type="EnsemblBacteria" id="ALN60629">
        <property type="protein sequence ID" value="ALN60629"/>
        <property type="gene ID" value="GLE_5288"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5288"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5206"/>
    <dbReference type="OMA" id="SLKFPYY"/>
    <dbReference type="OrthoDB" id="1970761at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025737">
        <property type="entry name" value="Phenol_MetA_deg_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13557">
        <property type="entry name" value="Phenol_MetA_deg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595412" evidence="2">
        <location>
            <begin position="21"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="56"/>
        </location>
    </feature>
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            <begin position="78"/>
            <end position="154"/>
        </location>
    </feature>
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        <location>
            <begin position="404"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="467" mass="49333" checksum="EFCF5DFEA127EB02" modified="2016-02-17" version="1">MRAAPLSLVLAATLAAPTHAAGASASDGAPSDEAASDPSSSPPPFASLHQRMLEMSRELAAQRAEIERLRGEVDELELAGRGRGLGPSQTAAPDGAQQGAPRDARELAQDARRKAADDARGEGQAAPGNSGDGAAPVQIGQAQRDEDAQRREQEKALVVREHAPLFERRFTFDAGISYSYYDRRQLALSGFLALDAIFLGSINLDQTKASIGTVELSGRYGLSDRLSVEASLPYVYRDSRFVSGGAGGASSVVSEVRMRSQGLGDASVAAYYQWVKESQRWPDIVTSLRVRAPTGRDPFGLKLVQPDADNNNLNIPEDLPTGSGVWAATFNVSALRTYDPVILFGNLGYTYNQPRDFDDISPVAEQVSPARVALGNTVQLSGGLAIALNDRSAVSFSVASASTGATHTTAPGARKRRVAGSSSNSTTFNIGASYVLPSGWTFNGQLAAGLTPDAPNFVFSLRGSRSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQC2</accession>
    <name>A0A0S2DQC2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_5425</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5425"/>
    <dbReference type="EnsemblBacteria" id="ALN60766">
        <property type="protein sequence ID" value="ALN60766"/>
        <property type="gene ID" value="GLE_5425"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5425"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5341"/>
    <dbReference type="OMA" id="QSDGQGC"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595645" evidence="1">
        <location>
            <begin position="23"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="287"/>
            <end position="552"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="592" mass="61444" checksum="24A83B9FFF90E036" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQD2</accession>
    <name>A0A0S2DQD2_LYSEN</name>
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        </submittedName>
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        <name evidence="3" type="ORF">GLE_5154</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
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    </dbReference>
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            <begin position="33"/>
            <end position="51"/>
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        <location>
            <begin position="94"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="271" mass="29523" checksum="44E4657743894D10" modified="2016-02-17" version="1">MHAMNAPPPHAGAVAPTGASAARALRYLVRTPLLLWHVFVHLPLVLLLITLPTARIPWGDIPLEHRVIRAWSAGLMRVFGFRLRRIGTPLPGAALFVANHVSWVDIEILHSQRMMGFVAKREIAGWPVVGWLAARGHTIFHSRGSTESLGGVLHEMLARLRAGRSVGVFPEGGTRGGREIGPFHARIFMAAVEAGVPVQPVALRYGERGDAQAVVAFQGRESFFANFLRLLGEPGRLAEVHFLAPIGPGEADGRRRIAELARQRIVEAMAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQE7</accession>
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        <submittedName>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="73" mass="7776" checksum="863AF9AEF1D2B7DB" modified="2016-02-17" version="1">MRNGKPMPGSVLIRHFAGHDHVVTVKADGNFDYRGQSFTSLSALAKHITGTPWSGPVFFGLRGAGTKPKGGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQL9</accession>
    <name>A0A0S2DQL9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Biopolymer transport exbD2 protein, putative</fullName>
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        <submittedName>
            <fullName evidence="9">Biopolymer transporter ExbD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BV903_04890</name>
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        <name evidence="8" type="ORF">GLE_5328</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD65077.1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN60669">
        <property type="protein sequence ID" value="ALN60669"/>
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    </dbReference>
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        <property type="gene ID" value="BV903_04890"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5328"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5245"/>
    <dbReference type="OMA" id="QGMMENE"/>
    <dbReference type="OrthoDB" id="1940365at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="6" id="KW-0813">Transport</keyword>
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        <location>
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    </evidence>
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    </evidence>
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    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQS8</accession>
    <name>A0A0S2DQS8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5510</name>
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    <organism evidence="1 2">
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60851">
        <property type="protein sequence ID" value="ALN60851"/>
        <property type="gene ID" value="GLE_5510"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5510"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="47" mass="4904" checksum="8E576743E00AF8B2" modified="2016-02-17" version="1">MLFLSDALSSNRSLFPPLSAPPESSGGGVVPKTALSLYAMPDSFLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQV3</accession>
    <name>A0A0S2DQV3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_00850</name>
        <name evidence="2" type="ORF">GLE_5528</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60869">
        <property type="protein sequence ID" value="ALN60869"/>
        <property type="gene ID" value="GLE_5528"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5528"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5444"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242476" evidence="1">
        <location>
            <begin position="24"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="141" mass="15671" checksum="04FDE666A2CE9B73" modified="2016-02-17" version="1">MKQKHFVFFAALLVVATGVPCAAADLPTTCDDDASAAVRSELFRNSRTANLYRATVNGDKESATALAVEIGKTHPDYVKCINRLGAENGDPIAQYNYSTWLTESKDEVTRLRGMYWLRRAATANHELAKEKLAEYRSGKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA21</accession>
    <name>A0A0S2DA21_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_01065</name>
        <name evidence="1" type="ORF">GLE_0026</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945737.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0026"/>
    <dbReference type="EnsemblBacteria" id="ALN55385">
        <property type="protein sequence ID" value="ALN55385"/>
        <property type="gene ID" value="GLE_0026"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0026"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.33"/>
    <dbReference type="OMA" id="CFAWCKT"/>
    <dbReference type="OrthoDB" id="604894at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="275" mass="30698" checksum="331B0ADDCCECE231" modified="2016-02-17" version="1">MTLPIITADQRLAEARGVKGVLVGRWGLGKTYQLWTLDPATTLFVDIEAGDLAVKNWPGDSLRPRTWDDCRDLAVFLGGPNPALRDGQYFSQWHYDQACLKYGDPKVLDRYRTLFIDSITVAGRLCLQWCKGQPQAFSERTNKPDMRGAYGLLGQEMVAWLTHIQHARGRHVWFVGILDERTDDFNRRYYELQIDGSKTGLELPGIVDEVITLAEIPAAEGKPYRAFVCQTANPWGFPAKDRSGRLDVVEPPNLGLLMTKLGAPEAAAPSPSSTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAF6</accession>
    <name>A0A0S2DAF6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0064</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55423">
        <property type="protein sequence ID" value="ALN55423"/>
        <property type="gene ID" value="GLE_0064"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0064"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.70"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="38" mass="4027" checksum="3AEBAEFF0CF43CCC" modified="2016-02-17" version="1">MNPSSRHCPSQPVAPAAGAARRSRERAGCAARVRTPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAH5</accession>
    <name>A0A0S2DAH5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GFA family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Glutathione-dependent formaldehyde-activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_01725</name>
        <name evidence="4" type="ORF">GLE_0170</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945845.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0170"/>
    <dbReference type="EnsemblBacteria" id="ALN55529">
        <property type="protein sequence ID" value="ALN55529"/>
        <property type="gene ID" value="GLE_0170"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0170"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.172"/>
    <dbReference type="OMA" id="ACQKRTG"/>
    <dbReference type="OrthoDB" id="1555973at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="3">
        <location>
            <begin position="4"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN55529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW24585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="132" mass="13996" checksum="FDED316AFEC9F60F" modified="2016-02-17" version="1">MSRRTASCACGQLSLDCEGEPLRISICHCLACQRRTGSAFGYQVRYPEAAVAIRGRFSGYAQAGDSGNVARFGFCPQCGSTVFWRPDALPGIVLVAAGAFADPAFPPPPTVSVYGDRRHAWVALPPGCEALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAS4</accession>
    <name>A0A0S2DAS4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YCII domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_12930</name>
        <name evidence="5" type="ORF">FE772_02055</name>
        <name evidence="3" type="ORF">GLE_0245</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YciI family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000032">
        <property type="protein sequence ID" value="OPD63524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945898.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0245"/>
    <dbReference type="EnsemblBacteria" id="ALN55604">
        <property type="protein sequence ID" value="ALN55604"/>
        <property type="gene ID" value="GLE_0245"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63524">
        <property type="protein sequence ID" value="OPD63524"/>
        <property type="gene ID" value="BV903_12930"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0245"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.247"/>
    <dbReference type="OMA" id="TVHEWNT"/>
    <dbReference type="OrthoDB" id="1780176at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII" evidence="2">
        <location>
            <begin position="21"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD63524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW24640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="84" mass="9424" checksum="F077EC17732F604D" modified="2016-02-17" version="1">MNRYLVMVMRLPQFDTEQIGPHREFLDGLRAQARLELSGGFGDKTGGAYVLRAVDLEEARVLAFADPLHLTGSSRVDVYEWQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAS6</accession>
    <name>A0A0S2DAS6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0276</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="gene ID" value="GLE_0276"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0276"/>
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    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="ALN55634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="217" mass="25795" checksum="B8B13A10C53532E1" modified="2016-02-17" version="1">MDIGAMDRREDLIELKDLRIPVERAQLHGWLYEDAGGEPRWSIEVSGRAQRFGDGDFAQALSPRFYDESLPLRIGDWRELEQQRCRFRWQDDEDQGDSLPTLYLCSHLSLPLSELSLGARDGRRFALRWTGLAEANWDEDYGREMPFRIELQIPFVEQEVRFWQRGDDEEVETAARAILRKRGLSDAHLRYREYRRFRDDPGDEHYRLLRAFFDPVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB68</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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        <name evidence="2" type="ORF">GLE_0411</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
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            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946015.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55769">
        <property type="protein sequence ID" value="ALN55769"/>
        <property type="gene ID" value="GLE_0411"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0411"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.408"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242545" evidence="1">
        <location>
            <begin position="26"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="66" mass="7212" checksum="3564316962EE5880" modified="2016-02-17" version="1">MNVKIRLVALCVFSFGLSFSSVVFASTCENDCARGLYNCYRDGGTEAKCEKFYGICMYNCEVAGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBC2</accession>
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        <submittedName>
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        </submittedName>
    </protein>
    <gene>
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        </lineage>
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    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.</text>
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        <property type="gene ID" value="GLE_0401"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0401"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.398"/>
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        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Ig-like_fold"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ChtBD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        </location>
    </feature>
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        <location>
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            <end position="593"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN55759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="594" mass="60817" checksum="0DDD7319035BD9CD" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBD0</accession>
    <name>A0A0S2DBD0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0469</name>
    </gene>
    <organism evidence="2 3">
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        <lineage>
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    <reference evidence="2 3" key="1">
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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    </dbReference>
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            <end position="26"/>
        </location>
    </feature>
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        <location>
            <begin position="27"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="87" mass="9088" checksum="A509B2D2CADBD42F" modified="2016-02-17" version="1">MKGWIGKGAASAFFVGLMIAAAPAAAEPTYECTASAEGHMFLVPYDHPRDPGYYYQCRGGAWRLIAVCSQSAGCPPAPDPGGPIVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBK7</accession>
    <name>A0A0S2DBK7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0557</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55915">
        <property type="protein sequence ID" value="ALN55915"/>
        <property type="gene ID" value="GLE_0557"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0557"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.551"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="72" mass="8175" checksum="ACF4295C89455896" modified="2016-02-17" version="1">MVGGWWLVVLGRGRAFRAGGSRPWEGLQARRFPIRRRVARTDQKANWAALCPSFRRKPESSLTSLLLLPLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBQ1</accession>
    <name>A0A0S2DBQ1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Linear gramicidin synthetase subunit B</fullName>
            <ecNumber evidence="6">5.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lgrB</name>
        <name evidence="6" type="ORF">GLE_0545</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0545"/>
    <dbReference type="EnsemblBacteria" id="ALN55903">
        <property type="protein sequence ID" value="ALN55903"/>
        <property type="gene ID" value="GLE_0545"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0545"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.539"/>
    <dbReference type="OMA" id="MIPSEWV"/>
    <dbReference type="OrthoDB" id="572620at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043604">
        <property type="term" value="P:amide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
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        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
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        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="1003"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1038"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN55903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1114" mass="121562" checksum="E5AE7CC6531CEBA1" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBS6</accession>
    <name>A0A0S2DBS6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">TonB family C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLE_0614</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TonB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946164.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0614"/>
    <dbReference type="EnsemblBacteria" id="ALN55972">
        <property type="protein sequence ID" value="ALN55972"/>
        <property type="gene ID" value="GLE_0614"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0614"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.606"/>
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    <dbReference type="OrthoDB" id="2074833at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="TonB_C" evidence="10">
        <location>
            <begin position="200"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="89"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN55972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="278" mass="28914" checksum="85BF5FE8A96EEB7D" modified="2016-02-17" version="1">MSAPALQATSAARAMRACSRTLPRARPHGPRPAAREREPWLGGVAVTAALHAALLVALLQLRTPAPATPPTPPAAAVVLELSLLPQAPPAPALDLPPGPAQPERAASRARPPRDVARKRPLPQPPQTLGDTASAPQPAARSEPVEATAAQEQTAASASAPPAVAAVPAPRYAAAQDAAGAGREVPRHWQQLLLGHLERFKRYPRQARRLHQQGVAQLHMTVAGDGGVRAARIEASSGYPGLDEEALAVAQRASPVPAPPADLGDPVEVVVPVEFYIAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBZ9</accession>
    <name>A0A0S2DBZ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BV903_08465</name>
        <name evidence="5" type="ORF">GLE_0699</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000017">
        <property type="protein sequence ID" value="OPD64443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946227.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000017.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0699"/>
    <dbReference type="EnsemblBacteria" id="ALN56057">
        <property type="protein sequence ID" value="ALN56057"/>
        <property type="gene ID" value="GLE_0699"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64443">
        <property type="protein sequence ID" value="OPD64443"/>
        <property type="gene ID" value="BV903_08465"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0699"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.687"/>
    <dbReference type="OMA" id="ALINCPK"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD64443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="240" mass="26231" checksum="DDF477A92173E923" modified="2016-02-17" version="1">MLQMRQVTKVYRTELVETHALRSLDLHVRDGEFVAVTGPSGSGKTTFLNIAGLLETFTGGEYTLDGENVSGLSDDARSRLRNQKIGFIFQSFNLIPDLNLFDNCDVPLRYRRMPAAERRERIEQALTQVGLGSRMRHYPTELSGGQQQRAAIARALAGSPRLLLADEPTGNLDSQMARGVMELLEDINAQGTTIVMVTHDPELAARAQRNVHIVDGMATDLRAEPSLIRAAAGATADATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC10</accession>
    <name>A0A0S2DC10_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Efflux RND transporter periplasmic adaptor subunit</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_04180</name>
        <name evidence="4" type="ORF">GLE_0701</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946229.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0701"/>
    <dbReference type="EnsemblBacteria" id="ALN56059">
        <property type="protein sequence ID" value="ALN56059"/>
        <property type="gene ID" value="GLE_0701"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0701"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.689"/>
    <dbReference type="OMA" id="GNWLTEQ"/>
    <dbReference type="OrthoDB" id="1432684at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="3">
        <location>
            <begin position="96"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW24990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="427" mass="45044" checksum="E620B6E37B05A9AC" modified="2016-02-17" version="1">MSIRDTSAQDHRVAPAAGRSRRRRQWALGAAVGALVLGAGAWVAAGWAAGGASVSAERLRIAEVKRGDLVRDIAADGRVIAANNPILYAIAGGSVDLKVVAGDVVRKGQVLAEIDSPELRSKLAQEQSTLAGLEAEASRAELDGELARSTARKEFDQAGIDRVAAERDLERYNRAFEGGAVAKVDVAKAQDELKKAEIGLSHAREGLGRQDRSAALDARNKRLLAQRQAAIVAEAQRQVDALTLRAPFDGQVGQVQVAQRANVAINDPVLSVVDLSVFEVEIKVPESFARDLAIGMPAQIAGNDGKSYAARISAVSPEVVAGEVVSRLRFAGAQPPALRQNQRLSARIVLDTRRNALTVERGPFLEQDGGTTAYVVAGGVATRRAIRTGASSLSQVEILEGLQPGERIVVSGADQFANAATVRISGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC19</accession>
    <name>A0A0S2DC19_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0712</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946240.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56070">
        <property type="protein sequence ID" value="ALN56070"/>
        <property type="gene ID" value="GLE_0712"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0712"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.700"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="649"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="956"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="696"/>
            <end position="750"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1108" mass="116471" checksum="CBF852400873C53C" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC26</accession>
    <name>A0A0S2DC26_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_04205</name>
        <name evidence="1" type="ORF">GLE_0706</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946234.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56064">
        <property type="protein sequence ID" value="ALN56064"/>
        <property type="gene ID" value="GLE_0706"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0706"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.694"/>
    <dbReference type="OrthoDB" id="2115927at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="295" mass="31859" checksum="9D62BAE5428B929E" modified="2016-02-17" version="1">MLALRHIGRAGGLVLAALLCGCVNLGPVREFAGSSARLTGYQGVTERYVTSADRQLADLPPDKRYDPLRAKLQNLRTVSARDKDTLLKLHATTTGYMAALALLAGEDAYSVAGELGKVSDAIAASEDLHIDAGHVQAYSNIAQRVVDWALAVQQAKDVKRMVERNGEDMDKLLEAMELATQAYGIVLRDEAASYDARSELREAAWTAELKGDSELTPARRDAVVTLLRRTARIDKAAQADALKAQQAAADGLAQVRAAHSALVRNVDRLDDKQLQATLRKAAADLKSIRQSFATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC57</accession>
    <name>A0A0S2DC57_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_04200</name>
        <name evidence="1" type="ORF">GLE_0705</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946233.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56063">
        <property type="protein sequence ID" value="ALN56063"/>
        <property type="gene ID" value="GLE_0705"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0705"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.693"/>
    <dbReference type="OrthoDB" id="2193389at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="133" mass="13708" checksum="9CB183D5E66C8023" modified="2016-02-17" version="1">MPTPLAQAKKSAFDIANQLDDAADAIRDRSRQAYAAGKMSLDEYTDARIKEMELRAEASVVAAVNLGAALDAGAQAGQNIEQAIADAKARIETVKTFRKGLEIVAALVVLAGALASGNAKAVVKAGKGVADLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCC6</accession>
    <name>A0A0S2DCC6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein-L-isoaspartate O-methyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">L-isoaspartyl protein carboxyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Protein L-isoaspartyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Protein-beta-aspartate methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BV903_09525</name>
        <name evidence="8" type="ORF">FE772_04710</name>
        <name evidence="6" type="ORF">GLE_0808</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">C3</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000021">
        <property type="protein sequence ID" value="OPD64120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946312.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0808"/>
    <dbReference type="EnsemblBacteria" id="ALN56166">
        <property type="protein sequence ID" value="ALN56166"/>
        <property type="gene ID" value="GLE_0808"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64120">
        <property type="protein sequence ID" value="OPD64120"/>
        <property type="gene ID" value="BV903_09525"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0808"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.797"/>
    <dbReference type="OMA" id="QIRTWEV"/>
    <dbReference type="OrthoDB" id="1948290at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004719">
        <property type="term" value="F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005369"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013346"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00030757"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00031323"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00031350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN56166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD64120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW25077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="222" mass="24230" checksum="71002DD85BB655DA" modified="2016-02-17" version="1">MTTIDYAKARELMVEQQVRPWDVLDPRVLDVLAELPREAFVADAHKNLAYADLALPLAHGEFMMKPVMEGRTLQSLAVDPTDDVLEIGTGSGYLTACLGRLAREVVSLEIHPDLAATARQRLAAQTILNAQVVDADALNYSTDRRFNAICVTGAVSQIPAQWLQWLQPGGRLFVVRGRSPAMEAVLVGGGERNEVNASRIQSLFETDLAYLQGAAPAPAFEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCE4</accession>
    <name>A0A0S2DCE4_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0839</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56197.1"/>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56197">
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        <property type="gene ID" value="GLE_0839"/>
    </dbReference>
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    <dbReference type="PATRIC" id="fig|69.6.peg.828"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="159" mass="18358" checksum="D27E15F09A402FC3" modified="2016-02-17" version="1">MLVAARIRMRCDPYRLRCAHDASASRRHDRDAVDSSDFRGICAVGAHRARRARMRVRAFELNESFSRREIREGSRYAWRSHSCDADTNVDATRRNERNATQRNATNAQRIRAAMLNDSFMPALLLHTHACKHERTASPHSRTNDARCKPLRQRSVSIDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCR2</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0967</name>
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    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
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        </lineage>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ALN56325">
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        <property type="gene ID" value="GLE_0967"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0967"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.954"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="48" mass="5263" checksum="F24741F630876698" modified="2016-02-17" version="1">MRNHVSSHRSRNRAGPSWPAPRAAPANVSGRLVQAQRARRAWAGRASC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCR7</accession>
    <name>A0A0S2DCR7_LYSEN</name>
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        <submittedName>
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        </submittedName>
        <submittedName>
            <fullName evidence="5">Ribonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_04585</name>
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    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EndA/NucM nuclease family.</text>
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    <dbReference type="EC" id="3.1.-.-" evidence="4"/>
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        <property type="protein sequence ID" value="ALN56136.1"/>
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    </dbReference>
    <dbReference type="EMBL" id="CP040656">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0778"/>
    <dbReference type="EnsemblBacteria" id="ALN56136">
        <property type="protein sequence ID" value="ALN56136"/>
        <property type="gene ID" value="GLE_0778"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0778"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.767"/>
    <dbReference type="OMA" id="QTFGACN"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007346">
        <property type="entry name" value="Endonuclease-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032812">
        <property type="entry name" value="SbsA_Ig"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33607">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Big_5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Endonuclease_1"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
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        <location>
            <begin position="39"/>
            <end position="604"/>
        </location>
    </feature>
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        <location>
            <begin position="211"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="604" mass="62365" checksum="0243E9087504EF62" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCZ4</accession>
    <name>A0A0S2DCZ4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1053</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56411">
        <property type="protein sequence ID" value="ALN56411"/>
        <property type="gene ID" value="GLE_1053"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1053"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1042"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="60" mass="6553" checksum="5D4E74914517ED2C" modified="2016-02-17" version="1">MRTILKSKAVGGAAVAQAACGEPKIQAFQSFRCCQNDSGRAFRPDAFRPGCRDLKQEHRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD46</accession>
    <name>A0A0S2DD46_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FE772_06070</name>
        <name evidence="9" type="ORF">GLE_1104</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW25291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946528.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1104"/>
    <dbReference type="EnsemblBacteria" id="ALN56462">
        <property type="protein sequence ID" value="ALN56462"/>
        <property type="gene ID" value="GLE_1104"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1104"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1091"/>
    <dbReference type="OMA" id="REHAQAY"/>
    <dbReference type="OrthoDB" id="71288at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
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</entry>
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</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
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        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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</entry>
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                <person name="Fernandez C."/>
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            <authorList>
                <person name="Feng T."/>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Feng T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56898">
        <property type="protein sequence ID" value="ALN56898"/>
        <property type="gene ID" value="GLE_1541"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1541"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1523"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="184" mass="19785" checksum="EDF444AFD52FE03D" modified="2016-02-17" version="1">MTDDAAGDTRPFPPELSALRSQARRAFECARTGLLWLALGICIAFLAPKVGELWLTYVAGGAVFVAALVHCRAAAAETRFALDAHRYLGEQWNASPLPGLAGLLRRGRRRLRSAAAAWALAAMVALLVVPIGLTFEVPVALRVHGLVLLLSAGRLQHMATVDRRLLREIGEHVRGLPRGDIVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEJ3</accession>
    <name>A0A0S2DEJ3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_07495</name>
        <name evidence="1" type="ORF">GLE_1419</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946762.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1419"/>
    <dbReference type="EnsemblBacteria" id="ALN56776">
        <property type="protein sequence ID" value="ALN56776"/>
        <property type="gene ID" value="GLE_1419"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1419"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1398"/>
    <dbReference type="OMA" id="GERQCAV"/>
    <dbReference type="OrthoDB" id="2061118at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="85" mass="9196" checksum="2F4CEF76CFFFC042" modified="2016-02-17" version="1">MSASTEPLLALLAQHPDGLSLPRVCKRLGLRMSVLLRELAWLGEEAIGDTPGPGWVRVDERGETRVAVLTERGRARLAAACEAPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEK1</accession>
    <name>A0A0S2DEK1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 9 10">2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase</fullName>
            <shortName evidence="9">MECDP-synthase</shortName>
            <shortName evidence="9">MECPP-synthase</shortName>
            <shortName evidence="9">MECPS</shortName>
            <ecNumber evidence="5 9 10">4.6.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 12" type="primary">ispF</name>
        <name evidence="13" type="ORF">FE772_07825</name>
        <name evidence="12" type="ORF">GLE_1491</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">C3</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9 10">
            <text>4-CDP-2-C-methyl-D-erythritol 2-phosphate = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + CMP</text>
            <dbReference type="Rhea" id="RHEA:23864"/>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
            <dbReference type="ChEBI" id="CHEBI:58483"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="4.6.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="9">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 4/6.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 9">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9 10">Belongs to the IspF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.12" evidence="5 9 10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946818.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1491"/>
    <dbReference type="EnsemblBacteria" id="ALN56848">
        <property type="protein sequence ID" value="ALN56848"/>
        <property type="gene ID" value="GLE_1491"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1491"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1472"/>
    <dbReference type="OMA" id="QHFGTGR"/>
    <dbReference type="OrthoDB" id="1716560at2"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008685">
        <property type="term" value="F:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00554">
        <property type="entry name" value="MECDP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00107">
        <property type="entry name" value="IspF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003526">
        <property type="entry name" value="MECDP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020555">
        <property type="entry name" value="MECDP_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036571">
        <property type="entry name" value="MECDP_synthase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43181">
        <property type="entry name" value="PTHR43181"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02542">
        <property type="entry name" value="YgbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69765">
        <property type="entry name" value="SSF69765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00151">
        <property type="entry name" value="ispF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01350">
        <property type="entry name" value="ISPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 10" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="8 9 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YgbB" evidence="11">
        <location>
            <begin position="3"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="9">
        <location>
            <begin position="10"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="9">
        <location>
            <begin position="36"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="9">
        <location>
            <begin position="58"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="4-CDP-2-C-methyl-D-erythritol 2-phosphate binding" evidence="9">
        <location>
            <begin position="134"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>4-CDP-2-C-methyl-D-erythritol 2-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>4-CDP-2-C-methyl-D-erythritol 2-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="9">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="9">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN56848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW25588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="159" mass="16612" checksum="6BF638D55237A9FA" modified="2016-02-17" version="1">MNIRIGQGYDVHAFGDGDHVMLGGVRVAHERGVIAHSDGDVVLHALCDAMLGALALGDIGKHFPPSDERWRGADSRAFLRHCNDLIAQRGYAVGNCDVTVVCERPKVGPHAQAMRESIAADLGIAVDAVSVKATTSEKLGFTGRGEGIAATAVCLLVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEM1</accession>
    <name>A0A0S2DEM1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acyl-CoA thioesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BV903_13185</name>
        <name evidence="8" type="ORF">D9T17_20030</name>
        <name evidence="7" type="ORF">FE772_07630</name>
        <name evidence="5" type="ORF">GLE_1451</name>
    </gene>
    <organism evidence="5 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 9">C3</strain>
        </source>
    </reference>
    <reference evidence="6 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">OH11</strain>
        </source>
    </reference>
    <reference evidence="7 12" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 12">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acyl coenzyme A hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000033">
        <property type="protein sequence ID" value="OPD63485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000048">
        <property type="protein sequence ID" value="ROU05124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946784.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000048.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1451"/>
    <dbReference type="EnsemblBacteria" id="ALN56808">
        <property type="protein sequence ID" value="ALN56808"/>
        <property type="gene ID" value="GLE_1451"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63485">
        <property type="protein sequence ID" value="OPD63485"/>
        <property type="gene ID" value="BV903_13185"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1451"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1431"/>
    <dbReference type="OMA" id="KWIDQAG"/>
    <dbReference type="OrthoDB" id="1712258at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016790">
        <property type="term" value="F:thiolester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040170">
        <property type="entry name" value="Cytosol_ACT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033120">
        <property type="entry name" value="HOTDOG_ACOT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11049">
        <property type="entry name" value="PTHR11049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51770">
        <property type="entry name" value="HOTDOG_ACOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HotDog ACOT-type" evidence="4">
        <location>
            <begin position="4"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD63485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW25551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROU05124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="165" mass="18079" checksum="9840B1087D79DE61" modified="2016-02-17" version="1">MKGQQRELNLRFLAQPTDVNYGGKVHGGMVMKWIDQAGYAAAVGWSGKYSVTVAVGGIRFVAPIRISDLVTVHTKLIHTGTSSMHFAVDVKARDPGLDDGEPEERLCTHCVIVFVAMDTVEGKPTPVPPWTPVTDDDKRLAEYALKVMELSKGIEATVERYVHEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DES2</accession>
    <name>A0A0S2DES2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FE772_09200</name>
        <name evidence="9" type="ORF">GLE_1789</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947049.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1789"/>
    <dbReference type="EnsemblBacteria" id="ALN57142">
        <property type="protein sequence ID" value="ALN57142"/>
        <property type="gene ID" value="GLE_1789"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1789"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1762"/>
    <dbReference type="OMA" id="YNMSHEL"/>
    <dbReference type="OrthoDB" id="1827824at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="191"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="251"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN57142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW25814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="455" mass="50650" checksum="80CE8624D8B61831" modified="2016-02-17" version="1">MSAPGWTASLARRWWPRRPAPARHGHFGLFVRYYLIVVLIYAVVVVGGISAWLCITDENSRAYGEAQLRGTHYLIEQRYLETPREDWPALGRELSERFAYPVRLASLAELRESLTAREWQRLQRGDVVMESEDEAYTYQRLPGTDQAVALGDFDDVMVQGVPWSELDLIDSIVILAMYFLAIALPLYFLVYRFWRDLRRLRTTAEALSAGELDARAPEVTTQLVNPLGHALNHMAGQVQQVLESQRILAQAVAHEIRTPLARMRFGLEMLEQAGGDDERAHLREGLETDIQRLEHLAAHSVAYARIGRMVGIEREPVPVAALLADLADVFEPEPPLMLSFDGGGVDCLPANREALELALRNLIANALRHARMRVAVSVARAGDGYALQVDDDGEGVPEADRERVFQPFAQLRKHPEGFGLGLALVRVIAEKHGGRASVADSALGGASFRIDLPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DES4</accession>
    <name>A0A0S2DES4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56928">
        <property type="protein sequence ID" value="ALN56928"/>
        <property type="gene ID" value="GLE_1571"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1571"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1551"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="105" mass="10983" checksum="90E42DC02DF09C95" modified="2016-02-17" version="1">MRGADGGARLFSADLSWAQAPQAPVRSRRLYVRRAVRIVLFALLALAAVGVVVINGPADAGPNRSAARALPDPVSEAEVEVDRAVALPAAPAAASRDRHERLAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF53</accession>
    <name>A0A0S2DF53_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">EAL domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">PAS domain S-box protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Sensory box-containing diguanylate cyclase/cyclic diguanylate phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BV903_23895</name>
        <name evidence="8" type="ORF">FE772_09295</name>
        <name evidence="6" type="ORF">GLE_1812</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">C3</strain>
        </source>
    </reference>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="64"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="201" mass="22509" checksum="7EAA31A4AF5EE57D" modified="2016-02-17" version="1">MPAQRPDAIAELRSTLSDYARRWPEEAGHTAPFLELLAETDEARGALQHDAAVWPDPFRRERLAGHFTGSAWLVDRAGARVLLTHHRKLGRWLQLGGHADGDRDLAAVALKEAEEESGLAGLSVEPQLFDLDRHWIPERGEVPGHWHYDLRYVVRAGDSEAFVVGEESLALAWREIDAVLADPDSDDSMRRLARKWLARGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFB7</accession>
    <name>A0A0S2DFB7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Serine protease, autotransporter barrel domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLE_1973</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1973"/>
    <dbReference type="EnsemblBacteria" id="ALN57323">
        <property type="protein sequence ID" value="ALN57323"/>
        <property type="gene ID" value="GLE_1973"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1973"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1938"/>
    <dbReference type="OMA" id="FERLEWA"/>
    <dbReference type="OrthoDB" id="1713183at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04848">
        <property type="entry name" value="Peptidases_S8_Autotransporter_serine_protease_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005546">
        <property type="entry name" value="Autotransporte_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036709">
        <property type="entry name" value="Autotransporte_beta_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013425">
        <property type="entry name" value="Autotrns_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034061">
        <property type="entry name" value="Peptidases_S8_Autotransporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03797">
        <property type="entry name" value="Autotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12951">
        <property type="entry name" value="PATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00869">
        <property type="entry name" value="Autotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103515">
        <property type="entry name" value="SSF103515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02601">
        <property type="entry name" value="autotrns_rpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51208">
        <property type="entry name" value="AUTOTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594760" evidence="7">
        <location>
            <begin position="22"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="domain" description="Autotransporter" evidence="8">
        <location>
            <begin position="656"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="25"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN57323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="928" mass="96117" checksum="F42B79796B6B8AD0" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFJ7</accession>
    <name>A0A0S2DFJ7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_09865</name>
        <name evidence="2" type="ORF">GLE_1939</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947155.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57290">
        <property type="protein sequence ID" value="ALN57290"/>
        <property type="gene ID" value="GLE_1939"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1939"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1904"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="13"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="195" mass="21674" checksum="086AB3EBDF697FF1" modified="2016-02-17" version="1">MSVKRPGLRWADLAAYTLAATGAAASAVLAMRPTGLRQLLAMGLSLLLLAALLACLVRAVRQWDKLRFGGLLAPAALLAAMPLGVEVGQELRTWRFERDLPRYQAMAKWALARAVPGERVDVPIPPEARDLAYLVRVSHEPGCGRIVDFYWGAGFPVKHTVRRYVELPQKLENDACRGYWARGLRRGEHWFEASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFV3</accession>
    <name>A0A0S2DFV3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methyl-accepting chemotaxis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_10150</name>
        <name evidence="4" type="ORF">GLE_1997</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57347">
        <property type="protein sequence ID" value="ALN57347"/>
        <property type="gene ID" value="GLE_1997"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1997"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1964"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="225"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="254"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="153"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="351" mass="38958" checksum="366148C54874BD09" modified="2016-02-17" version="1">MEDTIEGSEFDPMQALSYVSMVMRVVANDLKSVAVSPEMANAYGGFSNHYENYENTTNDLELSTSISGIAAHASTFLKNALKSPDTVGRNESIIRQAIEHAGKLADFARSMPINLAESIQSEPSPSAEETRRSELDRKNTELEQRLTTVSGSTTQLEERVAALTNEVKAELERAREEYGRGKARVDEETRNYADLLSHRAGEAINSDYADSARKELQSANSMRRVSLVFMVAAIAVLAITWLDHSAAVLTWEATTLRFLVALAFSVPAGYLARESARHRDQYHTYLRTALNLKSLAPYISSLPLEQQHLLKTEMAQRLFVINTQASAGDLGVINVHELLALLIKQLQELRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFX3</accession>
    <name>A0A0S2DFX3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Enolase-phosphatase E1</fullName>
            <ecNumber evidence="4">3.1.3.77</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">2,3-diketo-5-methylthio-1-phosphopentane phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">mtnC</name>
        <name evidence="7" type="ORF">FE772_09755</name>
        <name evidence="6" type="ORF">GLE_1910</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:49252"/>
            <dbReference type="ChEBI" id="CHEBI:58828"/>
            <dbReference type="EC" id="3.1.3.77"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="4">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 3/6.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 4/6.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.77" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947137.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1910"/>
    <dbReference type="EnsemblBacteria" id="ALN57261">
        <property type="protein sequence ID" value="ALN57261"/>
        <property type="gene ID" value="GLE_1910"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1910"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1878"/>
    <dbReference type="OMA" id="QLKGHVY"/>
    <dbReference type="OrthoDB" id="1204073at2"/>
    <dbReference type="UniPathway" id="UPA00904">
        <property type="reaction ID" value="UER00876"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043715">
        <property type="term" value="F:2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043716">
        <property type="term" value="F:2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043874">
        <property type="term" value="F:acireductone synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019284">
        <property type="term" value="P:L-methionine salvage from S-adenosylmethionine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01629">
        <property type="entry name" value="HAD_EP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01681">
        <property type="entry name" value="Salvage_MtnC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023943">
        <property type="entry name" value="Enolase-ppase_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00044">
        <property type="entry name" value="enolase-phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01691">
        <property type="entry name" value="enolase-ppase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="204"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW25906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="231" mass="25631" checksum="CE1512DCE4765F4F" modified="2016-02-17" version="1">MPIRAILTDIEGTTSSISFVKDVLFPYARRALPGFVAARGREPNVRKWLDAVAMEHGGVCQDSVVVEVLQGWIDEDRKHTALKALQGMIWADGYNSADFTSHMYPDAAPALRQWKDAGLRLYVYSSGSVPAQRLLFGHSDAGDLTELFSGFFDTEVGGKREAASYERIRESIGLAGDEILFLSDVVEELDAAREAGLETVLIDRREDYPQPREGDATHDHPRATSFDQIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFY2</accession>
    <name>A0A0S2DFY2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Acireductone dioxygenase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase</fullName>
            <shortName evidence="8">DHK-MTPene dioxygenase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Acireductone dioxygenase (Fe(2+)-requiring)</fullName>
            <shortName evidence="8">ARD'</shortName>
            <shortName evidence="8">Fe-ARD</shortName>
            <ecNumber evidence="8">1.13.11.54</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Acireductone dioxygenase (Ni(2+)-requiring)</fullName>
            <shortName evidence="8">ARD</shortName>
            <shortName evidence="8">Ni-ARD</shortName>
            <ecNumber evidence="8">1.13.11.53</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mtnD</name>
        <name evidence="10" type="ORF">FE772_09760</name>
        <name evidence="9" type="ORF">GLE_1911</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 3-(methylsulfanyl)propanoate + CO + formate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:14161"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:17245"/>
            <dbReference type="ChEBI" id="CHEBI:49016"/>
            <dbReference type="ChEBI" id="CHEBI:49252"/>
            <dbReference type="EC" id="1.13.11.53"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 4-methylsulfanyl-2-oxobutanoate + formate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:24504"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:16723"/>
            <dbReference type="ChEBI" id="CHEBI:49252"/>
            <dbReference type="EC" id="1.13.11.54"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="8">Binds 1 Fe(2+) cation per monomer.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
        <text evidence="8">Binds 1 nickel ion per monomer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 5/6.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the acireductone dioxygenase (ARD) family.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.54" evidence="8"/>
    <dbReference type="EC" id="1.13.11.53" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947138.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1911"/>
    <dbReference type="EnsemblBacteria" id="ALN57262">
        <property type="protein sequence ID" value="ALN57262"/>
        <property type="gene ID" value="GLE_1911"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1911"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1879"/>
    <dbReference type="OMA" id="TTHWFDM"/>
    <dbReference type="OrthoDB" id="1964262at2"/>
    <dbReference type="UniPathway" id="UPA00904">
        <property type="reaction ID" value="UER00878"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010308">
        <property type="term" value="F:acireductone dioxygenase (Ni2+-requiring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010309">
        <property type="term" value="F:acireductone dioxygenase [iron(II)-requiring] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019284">
        <property type="term" value="P:L-methionine salvage from S-adenosylmethionine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02232">
        <property type="entry name" value="cupin_ARD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01682">
        <property type="entry name" value="Salvage_MtnD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004313">
        <property type="entry name" value="ARD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023956">
        <property type="entry name" value="ARD_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23418">
        <property type="entry name" value="PTHR23418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03079">
        <property type="entry name" value="ARD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 8 9" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="1 8" id="KW-0533">Nickel</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <feature type="site" description="May play a role in metal incorporation in vivo" evidence="8">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="site" description="May play a role in transmitting local conformational changes" evidence="8">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <feature type="site" description="Important to generate the dianion" evidence="8">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN57262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW25907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="185" mass="20995" checksum="13C89344ADD03002" modified="2016-02-17" version="1">MSRLRIFREDQPDAPKLSTSDQAEIACELAKIGVGFEQWQASKPVKPGDTPETIMDAYRADIDRITVERGFKTVDVVSIAPDNPQRETMRGKFLDEHYHKEDEVRFFVAGSGLFTLHVEPNVYEIKCEQGDLISVPDSTLHWFDMGPEPSFVAIRFFTEPDGWVGYFTGTDLAQQFPRYEKGQAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG19</accession>
    <name>A0A0S2DG19_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Carbonic anhydrase</fullName>
            <ecNumber evidence="3 8">4.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BV903_10905</name>
        <name evidence="12" type="ORF">FE772_10040</name>
        <name evidence="10" type="ORF">GLE_1975</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">C3</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Reversible hydration of carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>H(+) + hydrogencarbonate = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the alpha-carbonic anhydrase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="3 8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000025">
        <property type="protein sequence ID" value="OPD63907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947182.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1975"/>
    <dbReference type="EnsemblBacteria" id="ALN57325">
        <property type="protein sequence ID" value="ALN57325"/>
        <property type="gene ID" value="GLE_1975"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63907">
        <property type="protein sequence ID" value="OPD63907"/>
        <property type="gene ID" value="BV903_10905"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1975"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1940"/>
    <dbReference type="OrthoDB" id="1572675at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03124">
        <property type="entry name" value="alpha_CA_prokaryotic_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041891">
        <property type="entry name" value="Alpha_CA_prokaryot-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001148">
        <property type="entry name" value="CA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036398">
        <property type="entry name" value="CA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023561">
        <property type="entry name" value="Carbonic_anhydrase_a-class"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018338">
        <property type="entry name" value="Carbonic_anhydrase_a-class_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952">
        <property type="entry name" value="PTHR18952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00194">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01057">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51069">
        <property type="entry name" value="SSF51069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00162">
        <property type="entry name" value="ALPHA_CA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51144">
        <property type="entry name" value="ALPHA_CA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="6 8" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594772" description="Carbonic anhydrase" evidence="8">
        <location>
            <begin position="27"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-carbonic anhydrase" evidence="9">
        <location>
            <begin position="39"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN57325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OPD63907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW25955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="254" mass="27928" checksum="6EE1C15446262795" modified="2016-02-17" version="1">MRSSEFAVPAVAVLSFALAAAFAARAEPPAKPAAAGHHEVYDYDRQEAWQALHDKSQSPVDIVAAGALAADPAEPGAIEFSHTHGAVDKVEDNGHAVQVDTHATEAIIRGRHFKLAQFHFHAQSEHTLDGKHFPLEGHFVFKAQDGRLAVVGVMYEQGKANPVAQEVLDDLRPGKAKPAQHEIDIEGLIPKSHGYYHYLGSLTTPPLTENVEWYVMPAPVTMSKQQIDGFLSHYRRNNRNIQPLNGRPLIRYEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG32</accession>
    <name>A0A0S2DG32_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methylthioribulose-1-phosphate dehydratase</fullName>
            <shortName evidence="1">MTRu-1-P dehydratase</shortName>
            <ecNumber evidence="1">4.2.1.109</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1 3" type="primary">mtnB</name>
        <name evidence="4" type="ORF">FE772_09765</name>
        <name evidence="3" type="ORF">GLE_1912</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-methyl-5-thio-D-ribulose 1-phosphate = 5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:15549"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58548"/>
            <dbReference type="ChEBI" id="CHEBI:58828"/>
            <dbReference type="EC" id="4.2.1.109"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 2/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldolase class II family. MtnB subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.109" evidence="1"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947139.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1912"/>
    <dbReference type="EnsemblBacteria" id="ALN57263">
        <property type="protein sequence ID" value="ALN57263"/>
        <property type="gene ID" value="GLE_1912"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1912"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1880"/>
    <dbReference type="OMA" id="IRGHGLY"/>
    <dbReference type="OrthoDB" id="599627at2"/>
    <dbReference type="UniPathway" id="UPA00904">
        <property type="reaction ID" value="UER00875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046570">
        <property type="term" value="F:methylthioribulose 1-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019284">
        <property type="term" value="P:L-methionine salvage from S-adenosylmethionine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005996">
        <property type="term" value="P:monosaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01677">
        <property type="entry name" value="Salvage_MtnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017714">
        <property type="entry name" value="MethylthioRu-1-P_deHdtase_MtnB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10640">
        <property type="entry name" value="PTHR10640"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="SSF53639"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03328">
        <property type="entry name" value="salvage_mtnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Aldolase_II" evidence="2">
        <location>
            <begin position="17"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="212" mass="23757" checksum="2703787D7862F33B" modified="2016-02-17" version="1">MNSPLPYDPQRLAHCAGEIIVNVRELAQRGWTPATSSNFSRRIDGQHVAITVSGRDKGRLTEDDIMVVDLDGAPVATSHRPSAETLLHTQLYKRYPEIGCVLHTHSQTQTVASRLYAGQGHVHLEGYELLKAFAGTTTHDTELDLPVYPNTQDMPTLAAQVDATLDQQTLWGYLIDGHGLYAWGRDMGEARRHLEAFEFLLGCELELRRLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG65</accession>
    <name>A0A0S2DG65_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Tryptophan synthase beta chain</fullName>
            <ecNumber evidence="11">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11 13" type="primary">trpB</name>
        <name evidence="14" type="ORF">FE772_10840</name>
        <name evidence="13" type="ORF">GLE_2147</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">C3</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 11">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the TrpB family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="11"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947316.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2147"/>
    <dbReference type="EnsemblBacteria" id="ALN57497">
        <property type="protein sequence ID" value="ALN57497"/>
        <property type="gene ID" value="GLE_2147"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2147"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2111"/>
    <dbReference type="OMA" id="HGMKSYF"/>
    <dbReference type="OrthoDB" id="912282at2"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06446">
        <property type="entry name" value="Trp-synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00133">
        <property type="entry name" value="Trp_synth_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006653">
        <property type="entry name" value="Trp_synth_b_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006654">
        <property type="entry name" value="Trp_synth_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023026">
        <property type="entry name" value="Trp_synth_beta/beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001413">
        <property type="entry name" value="Trp_syn_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00263">
        <property type="entry name" value="trpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00168">
        <property type="entry name" value="TRP_SYNTHASE_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="10 11 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="PALP" evidence="12">
        <location>
            <begin position="66"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="11">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN57497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW26093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="408" mass="43674" checksum="7450B6A6E96EEA8A" modified="2016-02-17" version="1">MSADPIAQPIDFHQYPDANGHFGRFGGRFVAETLIAPIEELARAYDAARVDPAFVQAFDNDLAHYVGRPSPIYHAQRLSDEVGGARILLKREDLNHTGAHKINNTIGQALLASRMGKTRIIAETGAGQHGVASATVAARLGLECVVYMGATDIERQKINVYRMKLLGATVVPVTSGSQTLKDALNEAMRDWVTNVRDTFYIIGTVAGPDPYPRMVRDFNAVVGREARAQMLAEYGRLPDAITACVGGGSNAIGLFHAFLNDRDVRIVGAEAAGDGIDTGRHAASLAAGRPGVLHGNRTYVLCDDDGQIVETHSVSAGLDYPGVGPEHAFLKDTGRAEYVGVTDDEALDAFRTLARTEGILAALESSHAIAQAIKLARSMPKDQVVLCNLSGRGDKDVHTIAGREGLHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG98</accession>
    <name>A0A0S2DG98_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57588">
        <property type="protein sequence ID" value="ALN57588"/>
        <property type="gene ID" value="GLE_2239"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2239"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2204"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="73" mass="8025" checksum="A0E97F0EB7DBED2E" modified="2016-02-17" version="1">MWEGLQARCFRRRSARSGRKASGLKALPQAFPFGFQGLSSAGLPRHNAPGHIFETTAPGPRIRPASHRRGTKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGF9</accession>
    <name>A0A0S2DGF9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">NADH-quinone oxidoreductase subunit L</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="10">Proton-translocating NADH-quinone oxidoreductase, chain L family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">nuoL</name>
        <name evidence="11" type="ORF">FE772_10950</name>
        <name evidence="10" type="ORF">GLE_2170</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947335.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2170"/>
    <dbReference type="EnsemblBacteria" id="ALN57520">
        <property type="protein sequence ID" value="ALN57520"/>
        <property type="gene ID" value="GLE_2170"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2170"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2133"/>
    <dbReference type="OMA" id="DDREEAW"/>
    <dbReference type="OrthoDB" id="1274678at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018393">
        <property type="entry name" value="NADHpl_OxRdtase_5_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003945">
        <property type="entry name" value="NU5C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001516">
        <property type="entry name" value="Proton_antipo_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42829">
        <property type="entry name" value="PTHR42829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00662">
        <property type="entry name" value="Proton_antipo_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01974">
        <property type="entry name" value="NDH_I_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="266"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="324"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="352"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="391"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="437"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="521"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="593"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="693"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_N" evidence="9">
        <location>
            <begin position="73"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="8">
        <location>
            <begin position="139"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="472"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN57520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW26112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="716" mass="78287" checksum="3F4395EC934ECDB7" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHF0</accession>
    <name>A0A0S2DHF0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RTX toxin-activating lysine-acyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_01505</name>
        <name evidence="3" type="ORF">GLE_2489</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">B25</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in fatty acylation of protoxin at internal lysine residues, thereby converting it to the active toxin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the RTX toxin acyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000003">
        <property type="protein sequence ID" value="OPD65699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947577.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2489"/>
    <dbReference type="EnsemblBacteria" id="ALN57838">
        <property type="protein sequence ID" value="ALN57838"/>
        <property type="gene ID" value="GLE_2489"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65699">
        <property type="protein sequence ID" value="OPD65699"/>
        <property type="gene ID" value="BV903_01505"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2489"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2451"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019835">
        <property type="term" value="P:cytolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009404">
        <property type="term" value="P:toxin metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003996">
        <property type="entry name" value="RTX_toxin-activating_protC_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02794">
        <property type="entry name" value="HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0204">Cytolysis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU368102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD65699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="165" mass="18807" checksum="54E9145430B5C80F" modified="2016-02-17" version="1">MIAIIEEPRSLSADFLKEIGAVAFVMARHERHRDRPVHALPSRIAPAAMARQIRVFYTAQSMPVGYLTWAWLNPQAERRWIEQPDAPLHPSEWTDGDALWLIDFVTLPGLERRLLNHAKDSLFADQPSIKALHRGADGAARKVSNWRRRGGAWRVADPHWHSARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHG2</accession>
    <name>A0A0S2DHG2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Efflux ABC transporter, permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLE_2505</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2505"/>
    <dbReference type="EnsemblBacteria" id="ALN57854">
        <property type="protein sequence ID" value="ALN57854"/>
        <property type="gene ID" value="GLE_2505"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2505"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2468"/>
    <dbReference type="OMA" id="IGENGIW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="259"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="305"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="354"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="291"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN57854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="395" mass="41188" checksum="C47E5332A54054AD" modified="2016-02-17" version="1">MRMLRLIAQAALMNLQGLSRRRLNALVMVVSIAGAVAVFSGVLAMNAGLDGAMRDAGRPDRAIVLRAGSTVEIASAISLDDVRAIQNSTQVRKNADGTVLLTAEAVGPITLVEKSSGLEVNGTIRGVGPEVLAVRPEIELVAGRMFEPGKFEVVVGRQAMEQFQGLTLGGQVAAYGTQWKIVGVFAARHSMRESELMADATVVMDVSRRPMFQNVTVVLPDAAGVAGFKQAVAANPGIAMDVFSEPEFLQRESRSLNGLLGFMAYVMGGIMALGAMFVAINAMYSSIDDRRREIATLRALGFPPLVVVSSIVVEAALLALLGGALGAVLAALVAGGRTVSTAVGADLRQLVFDVSMTPSVVLQGIAAALAIGVVGGLVPAIRAVRSQVVDDLRAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHU4</accession>
    <name>A0A0S2DHU4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2915</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947906.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58263">
        <property type="protein sequence ID" value="ALN58263"/>
        <property type="gene ID" value="GLE_2915"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2915"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2877"/>
    <dbReference type="OrthoDB" id="2094384at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595049" evidence="2">
        <location>
            <begin position="23"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="98" mass="9727" checksum="401DD1E7C80EDCAE" modified="2016-02-17" version="1">MRRTLAVSLASVLLSLSLGAIAAPQAAPAAQPTTAAKPAPATMPAAKPAAAAAPAKAAPAKAATERCRDAKGKFIACAKKAEATRCRDAKGKFTACPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI81</accession>
    <name>A0A0S2DI81_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Heme exporter protein C</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cytochrome c-type biogenesis protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">ccmC</name>
        <name evidence="11" type="ORF">FE772_14125</name>
        <name evidence="10" type="ORF">GLE_2828</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the CcmC/CycZ/HelC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947845.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2828"/>
    <dbReference type="EnsemblBacteria" id="ALN58176">
        <property type="protein sequence ID" value="ALN58176"/>
        <property type="gene ID" value="GLE_2828"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2828"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2786"/>
    <dbReference type="OMA" id="FHVPMWF"/>
    <dbReference type="OrthoDB" id="955123at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015232">
        <property type="term" value="F:heme transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002541">
        <property type="entry name" value="Cyt_c_assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003557">
        <property type="entry name" value="Cyt_c_biogenesis_CcmC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045062">
        <property type="entry name" value="Cyt_c_biogenesis_CcsA/CcmC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30071">
        <property type="entry name" value="PTHR30071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01578">
        <property type="entry name" value="Cytochrom_C_asm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01386">
        <property type="entry name" value="CCMCBIOGNSIS"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01191">
        <property type="entry name" value="ccmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="136"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_C_asm" evidence="9">
        <location>
            <begin position="44"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN58176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW26627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="250" mass="27977" checksum="44D7C12AD72B8707" modified="2016-02-17" version="1">MNPLVLWFHKLGSPPTFDRFAARWARWGYGLGLLVMAWGIYSALFVAPPHREQLDGFRIFYIHVPSAWMSLAVFALMAVYAAIALVWRIKLCEILAMACAPIGAGFTLITLATGSIWGKPMWGTWWEWDPRLTTELILLFLYLGVIGLYHAIDDRRAAARAAGLLAIVGVALLPVIRYSVVWWNSLHQGSTINMFGPSHMDPSMVPPLIWMLVGTKLWFVGALLARARADNLRRESGKAWVTELATGKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIB3</accession>
    <name>A0A0S2DIB3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Diacylglycerol O-acyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">FE772_13215</name>
        <name evidence="12" type="ORF">GLE_2635</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">C3</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycerol + an acyl-CoA = a triacyl-sn-glycerol + CoA</text>
            <dbReference type="Rhea" id="RHEA:10868"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:64615"/>
            <dbReference type="EC" id="2.3.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycerolipid metabolism; triacylglycerol biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the long-chain O-acyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.20" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947693.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2635"/>
    <dbReference type="EnsemblBacteria" id="ALN57983">
        <property type="protein sequence ID" value="ALN57983"/>
        <property type="gene ID" value="GLE_2635"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2635"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2594"/>
    <dbReference type="OMA" id="TAWLRMD"/>
    <dbReference type="OrthoDB" id="279287at2"/>
    <dbReference type="UniPathway" id="UPA00282"/>
    <dbReference type="UniPathway" id="UPA00356">
        <property type="reaction ID" value="UER00437"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004144">
        <property type="term" value="F:diacylglycerol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014292">
        <property type="entry name" value="Acyl_transf_WS/DGAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045034">
        <property type="entry name" value="O-acyltransferase_WSD1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009721">
        <property type="entry name" value="O-acyltransferase_WSD1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004255">
        <property type="entry name" value="O-acyltransferase_WSD1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31650">
        <property type="entry name" value="PTHR31650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03007">
        <property type="entry name" value="WES_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06974">
        <property type="entry name" value="WS_DGAT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02946">
        <property type="entry name" value="acyl_WS_DGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="WES_acyltransf" evidence="10">
        <location>
            <begin position="19"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="WS_DGAT_C" evidence="11">
        <location>
            <begin position="322"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN57983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW26480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="486" mass="53193" checksum="79FAB1DFEC08A33E" modified="2016-02-17" version="1">MAKAETGAGQRRRARREPMSRVDTAWLRMERPTNPMMITGVLMFAEPMSVDALRKVIKQRFLAYGRFRQKAVDTAAGAYWQTDDDLDLDWHVQHTALPGRGGKRALERFVSQLASSPLDPSRPLWQFHLVERYHGGSALVARLHHSYADGIALVQVLLSLTDTTAQPAKGSDLPHAWLKQDGADVARRVGAVERYMKLGSKAVEKSMEMYRDPTLAAMLAKEGGEIARELLHALSLSDDPPSMLRGKLGVSKRVAWAEPLDLEEVKAVGRACDCTVNDVLMATAAGALRSYMIERGDAVDGLTLRATVPVNLRPLEHARKLGNHFGLVFLDLPVGEANPIRRVERVAECMNNLKNSRQAIVAFGLLAALGMAPAQMQGLALELFSRKATAVATNVPGPQQPLYMAGCRLEEMMFWVPQTGSIGVGISILSYNGRVHFGLIADGKLIPDPDEVIGRFGAEFDKLLYLALMGDWNHALDAEGAAALMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIE3</accession>
    <name>A0A0S2DIE3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Type IV secretion system protein VirB9</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">VirB9 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">virB9</name>
        <name evidence="5" type="ORF">BV903_06255</name>
        <name evidence="6" type="ORF">FE772_14090</name>
        <name evidence="4" type="ORF">GLE_2821</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">C3</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TrbG/VirB9 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000011">
        <property type="protein sequence ID" value="OPD64806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947840.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000011.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2821"/>
    <dbReference type="EnsemblBacteria" id="ALN58169">
        <property type="protein sequence ID" value="ALN58169"/>
        <property type="gene ID" value="GLE_2821"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64806">
        <property type="protein sequence ID" value="OPD64806"/>
        <property type="gene ID" value="BV903_06255"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2821"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2778"/>
    <dbReference type="OMA" id="MPHSEDI"/>
    <dbReference type="OrthoDB" id="1251301at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd06911">
        <property type="entry name" value="VirB9_CagX_TrbG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010258">
        <property type="entry name" value="Conjugal_tfr_TrbG/VirB9/CagX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033645">
        <property type="entry name" value="VirB9/CagX/TrbG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038161">
        <property type="entry name" value="VirB9/CagX/TrbG_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03524">
        <property type="entry name" value="CagX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595239" evidence="3">
        <location>
            <begin position="27"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD64806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW26622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="255" mass="29057" checksum="0959648472F78E4D" modified="2016-02-17" version="1">MNCLRKQSLIALLLLAISGLALPASAQVVQEYEYEANRIYQVRTGLGITTQIELSPSENILDYSTGFSSGWDLSRRDNIFYLKPKNVDVDTNMMIRTTTHSYILELKVVATDWRVLEQAKQAGVQYKIKFVYPNGTEFSAAKESTEQTATELNTTLDKNRLYNFDYQFSSRKKQSWLVPTNVYDDGQFTYIKINALKDLPTGNFPAVFGREREGSEDFVVNTTVEGNTIIVHGTYPYLIIRHGNNVVGLRRKKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIG4</accession>
    <name>A0A0S2DIG4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GMP synthase [glutamine-hydrolyzing]</fullName>
            <ecNumber evidence="9">6.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">GMP synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Glutamine amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 12" type="primary">guaA</name>
        <name evidence="13" type="ORF">FE772_14435</name>
        <name evidence="12" type="ORF">GLE_2893</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">C3</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Catalyzes the synthesis of GMP from XMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O + L-glutamine + XMP = AMP + diphosphate + GMP + 2 H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.2" evidence="9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947886.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2893"/>
    <dbReference type="EnsemblBacteria" id="ALN58241">
        <property type="protein sequence ID" value="ALN58241"/>
        <property type="gene ID" value="GLE_2893"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2893"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2855"/>
    <dbReference type="OMA" id="KRKIIGH"/>
    <dbReference type="OrthoDB" id="504464at2"/>
    <dbReference type="UniPathway" id="UPA00189">
        <property type="reaction ID" value="UER00296"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003922">
        <property type="term" value="F:GMP synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016462">
        <property type="term" value="F:pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01742">
        <property type="entry name" value="GATase1_GMP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01997">
        <property type="entry name" value="GMP_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00344">
        <property type="entry name" value="GMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001674">
        <property type="entry name" value="GMP_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004739">
        <property type="entry name" value="GMP_synth_GATase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022955">
        <property type="entry name" value="GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025777">
        <property type="entry name" value="GMPS_ATP_PPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00958">
        <property type="entry name" value="GMP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00884">
        <property type="entry name" value="guaA_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00888">
        <property type="entry name" value="guaA_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51553">
        <property type="entry name" value="GMPS_ATP_PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5 9 10" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="3 9 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMPS ATP-PPase" evidence="11">
        <location>
            <begin position="205"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="232"/>
            <end position="238"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN58241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW26670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="522" mass="57483" checksum="E52E2EE00E11E01E" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIK8</accession>
    <name>A0A0S2DIK8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DnaJ domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_2731</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947772.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2731"/>
    <dbReference type="EnsemblBacteria" id="ALN58079">
        <property type="protein sequence ID" value="ALN58079"/>
        <property type="gene ID" value="GLE_2731"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2731"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2689"/>
    <dbReference type="OMA" id="WDAGFEF"/>
    <dbReference type="OrthoDB" id="1738789at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="SSF49493"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="4">
        <location>
            <begin position="5"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="298" mass="32071" checksum="E3E38C46B6A4D518" modified="2016-02-17" version="1">MQFKDYYETLGVEPSAGEAEIKTAYRRLARKYHPDVSKEAGAEESFKAVNEAYEALRDPQKRAAYDQLRVRGYRPGDEVQPPPGGFGGGPGGPDFEEIFAGGGAGGGFSDFFETLFGRGRAAPGAGGFQQRGAPPRGDTRARLAVSLETVYEGGQVRISVNHKTLDVRVPKGIRPGQLIRLAGQGTHGDLLLEIEYAAHPQFEVDGRNVIHVLELAPWEAALGASVSVPTLGGPVELKIPANSEAGRKLRLRGRGLPGSPAGDQIVELEVLAPRADNDAQREAYEGLRAAFGEDWRRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIR5</accession>
    <name>A0A0S2DIR5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Acyltransferase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_15380</name>
        <name evidence="3" type="ORF">GLE_3081</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948028.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3081"/>
    <dbReference type="EnsemblBacteria" id="ALN58428">
        <property type="protein sequence ID" value="ALN58428"/>
        <property type="gene ID" value="GLE_3081"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3081"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3040"/>
    <dbReference type="OMA" id="YFSYMLY"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
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            <end position="73"/>
        </location>
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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            <end position="167"/>
        </location>
    </feature>
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        </location>
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            <end position="238"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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            <end position="268"/>
        </location>
    </feature>
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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            <end position="335"/>
        </location>
    </feature>
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            <end position="360"/>
        </location>
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            <end position="359"/>
        </location>
    </feature>
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            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="397" mass="45233" checksum="D3B5E74DA6403906" modified="2016-02-17" version="1">MQRRYDIDALRALAFCLLILYHCAMLYVADWGWHLKSPHLSEGLQWPMLLVNRWRMDLIFLISGLSVHFLLRGTGAGRFLAQRSWRLLLPLTFGCLVVVPIQPYAQGVANGLVEPGFGAFLLRYYQFKPWPQGAFDGWQYGFTWNHLWYLAYLWVYTVVLAALLPLLRSRAGLRLQGALASLRGWALLVLPALPLALFSILLQPHFADTGDLIHDWHRHAIYFTVFLYGYWLGNDAGLWAELTRLRRRTLTLAPLLFAAYLALLKLLPEDVPDAVQYLIWTLRSAYIWTALCAILGWSHQLLNRPLRWLPWATEAVYPWYVLHQSLIVLIAYWILPLKFGPLAEPAIVLAGTVAGCFVLHEIVRRVPLLRPCFGLKARKRRAPAGLGPASAPAPKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ46</accession>
    <name>A0A0S2DJ46_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome C family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_2939</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2939"/>
    <dbReference type="EnsemblBacteria" id="ALN58287">
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        <property type="gene ID" value="GLE_2939"/>
    </dbReference>
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    <dbReference type="OMA" id="KVAMCIG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
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        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
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        <location>
            <begin position="23"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="50"/>
            <end position="131"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="131" mass="13449" checksum="055E5C47A4326AA9" modified="2016-02-17" version="1">MMRPLTIAACFALTLAAASAAAQDPAPAATAPAAAPATAAPAAAAPSIKGNPQTGRQLTYTCQGCHGVTGYKNAYPNYHVPKIVGQSPEYLANALSEYKKGTRKHPTMQAQAQSFSDQDIADIAAFLSSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ90</accession>
    <name>A0A0S2DJ90_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FHA domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_03025</name>
        <name evidence="3" type="ORF">GLE_2987</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD65505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_MTAY01000005.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2987"/>
    <dbReference type="EnsemblBacteria" id="ALN58335">
        <property type="protein sequence ID" value="ALN58335"/>
        <property type="gene ID" value="GLE_2987"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65505">
        <property type="protein sequence ID" value="OPD65505"/>
        <property type="gene ID" value="BV903_03025"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2987"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2948"/>
    <dbReference type="OMA" id="EEGSWIN"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
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        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032030">
        <property type="entry name" value="YscD_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16697">
        <property type="entry name" value="Yop-YscD_cpl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="133"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD65505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="267" mass="28747" checksum="D64391E20F5F99A3" modified="2016-02-17" version="1">MSALKLRYPNREHGDLALKPGVHAIGRDAAGRTVLVDDADAAIAQFSVDRRGVWLQVRDSLHGLHVNGRPVKRMAMLRPGDAIFIDGVELLLVADKPEPAPPFGVEIPADSRMVVRGVGGVHHGRCYTLEQPKVIGRAGDCDIRINEPAFADRHARLEAHADGVVLRDVGSVDGSVVNGQPVRHALLKPGDQLLLDGQHRFVIEAPTRRLSAADALQAQLAQEQAANEDKPIPPSALPSSVRRMPWLLLAAVVMAGLLGLLLLYGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJB0</accession>
    <name>A0A0S2DJB0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Heat shock protein 15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_3246</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the HSP15 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3246"/>
    <dbReference type="EnsemblBacteria" id="ALN58592">
        <property type="protein sequence ID" value="ALN58592"/>
        <property type="gene ID" value="GLE_3246"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3246"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3200"/>
    <dbReference type="OMA" id="IDKYLWC"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003727">
        <property type="term" value="F:single-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025708">
        <property type="entry name" value="HSP15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016821">
        <property type="entry name" value="HSP15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S4" evidence="4">
        <location>
            <begin position="22"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR016821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="146" mass="15979" checksum="53EEA679203ED73D" modified="2016-02-17" version="1">MVSFAPMSKQDETTGAPAQATVRLDLWLWAARFYKTRSLARQAVETGKVEVGGQRAKASRAVRLGDALKVARGEEHFEIAVTGLSDTRGPASLAQTLYAETEASRLAREQARALRAAERNGYRAPETKPDKRARRLIKALGDIDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJI9</accession>
    <name>A0A0S2DJI9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3354</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58700">
        <property type="protein sequence ID" value="ALN58700"/>
        <property type="gene ID" value="GLE_3354"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3354"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3304"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046116">
        <property type="entry name" value="DUF6053"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19523">
        <property type="entry name" value="DUF6053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="43" mass="4262" checksum="8AADAFDE80C1A4C4" modified="2016-02-17" version="1">MQAPPVDSPTRAALFVGGPSDVVPWPFVGGPSGPMPSAQIAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJK3</accession>
    <name>A0A0S2DJK3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58707">
        <property type="protein sequence ID" value="ALN58707"/>
        <property type="gene ID" value="GLE_3361"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3361"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3311"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046116">
        <property type="entry name" value="DUF6053"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19523">
        <property type="entry name" value="DUF6053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="37" mass="3646" checksum="36F777C716688958" modified="2016-02-17" version="1">MGGPSGPTLLAQLAAICNKSVGPEGPPTRAKPDLLMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJN3</accession>
    <name>A0A0S2DJN3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3393"/>
    <dbReference type="EnsemblBacteria" id="ALN58739">
        <property type="protein sequence ID" value="ALN58739"/>
        <property type="gene ID" value="GLE_3393"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3393"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3342"/>
    <dbReference type="OMA" id="NQRRDQY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003959">
        <property type="term" value="F:NADPH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02932">
        <property type="entry name" value="OYE_YqiM_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044152">
        <property type="entry name" value="YqjM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43303">
        <property type="entry name" value="PTHR43303"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_FMN" evidence="1">
        <location>
            <begin position="4"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="355" mass="38742" checksum="BBBCBB88E3981395" modified="2016-02-17" version="1">MSRLFAPLQQRSLTLRNRLAVSPMCQYSASDGLPNNWHLVHLGSRAVGGAGLVLTEACAVSPEGRISAADTGLWNASQAEAWHRVSCFLRSREAAVGVQLAHAGRKASVEAPWLGGRPVAPQDGGWTPVAASPLPYREGATRPRELQPIEIRTVVDDFAAAAQRALDACFQLVEIHAAHGYLLHQFLSPLSNRREDRYGGSFDNRTRLLREVLAAVREVWPERLPLWLRISATDWAEGGWDIEQSVELARMVKDLGVDLIDVSSGGLVPNARIPGDEPGYQVPFSARIRREAGIATGAVGLITRAAQAESIVAQDEADVVLLARELLRDPYFPHRAARELGAAGHVPEQYQRAWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJP2</accession>
    <name>A0A0S2DJP2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Queuine tRNA-ribosyltransferase</fullName>
            <ecNumber evidence="5">2.4.2.29</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Guanine insertion enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">tRNA-guanine transglycosylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">tgt</name>
        <name evidence="8" type="ORF">FE772_17305</name>
        <name evidence="7" type="ORF">GLE_3515</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>7-aminomethyl-7-carbaguanine + guanosine(34) in tRNA = 7-aminomethyl-7-carbaguanosine(34) in tRNA + guanine</text>
            <dbReference type="Rhea" id="RHEA:24104"/>
            <dbReference type="Rhea" id="RHEA-COMP:10341"/>
            <dbReference type="Rhea" id="RHEA-COMP:10342"/>
            <dbReference type="ChEBI" id="CHEBI:16235"/>
            <dbReference type="ChEBI" id="CHEBI:58703"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:82833"/>
            <dbReference type="EC" id="2.4.2.29"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the queuine tRNA-ribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.29" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948348.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3515"/>
    <dbReference type="EnsemblBacteria" id="ALN58859">
        <property type="protein sequence ID" value="ALN58859"/>
        <property type="gene ID" value="GLE_3515"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3515"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3459"/>
    <dbReference type="OMA" id="GIDLFDC"/>
    <dbReference type="OrthoDB" id="1165356at2"/>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008479">
        <property type="term" value="F:queuine tRNA-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101030">
        <property type="term" value="P:tRNA-guanine transglycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00168">
        <property type="entry name" value="Q_tRNA_Tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004803">
        <property type="entry name" value="TGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="SSF51713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00430">
        <property type="entry name" value="Q_tRNA_tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00449">
        <property type="entry name" value="tgt_general"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5 7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 5" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="TGT" evidence="6">
        <location>
            <begin position="15"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="92"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA binding" evidence="5">
        <location>
            <begin position="246"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA binding; important for wobble base 34 recognition" evidence="5">
        <location>
            <begin position="270"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="335"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW27132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="368" mass="40908" checksum="CA21691E081408BA" modified="2016-02-17" version="1">MSRMSFQLLGQDGAARRGRLTFPRGTVETPAFMPVGTYGSVKGIMPEHVRELGAQIILGNTFHLYLRPGLDVIGDHGGLHGFARWNGPILTDSGGFQVFSLAHRRKITEQGVTFASPVDGSKVFLGPEESMNIQRVLDSDIVMIFDECTPYPAAEDVARKSMELSLRWAERSKKAHEGNDAALFGIVQGGVHHGLRTRSAEALKALGFDGYAIGGLAVGEPEAERNEMLEHTCPQLPQDRPRYLMGVGRPEDLVESVARGVDMFDCVMPTRNARNGHYFTAQGTVRVRNAKYERDLRPIEEGCDCYACANGFSRAYLRHLDRCNEMLGPMLGTLHNLRYYQRLMAQMRAAIEQGTFAAFRESFYAARM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJZ6</accession>
    <name>A0A0S2DJZ6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_16875</name>
        <name evidence="4" type="ORF">FE772_17690</name>
        <name evidence="2" type="ORF">GLE_3590</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000045">
        <property type="protein sequence ID" value="OPD62767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58934">
        <property type="protein sequence ID" value="ALN58934"/>
        <property type="gene ID" value="GLE_3590"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62767">
        <property type="protein sequence ID" value="OPD62767"/>
        <property type="gene ID" value="BV903_16875"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3590"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3534"/>
    <dbReference type="OrthoDB" id="1987224at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="182" mass="20891" checksum="1601FB0B0A2D0FE4" modified="2016-02-17" version="1">MRGGPIGWLLVAHFVGALLSLISIEPGCCLFVPEEPDHDRVWRWLLLFWLALAAFSLVRHWPMWSWRSPAWMALLAPWVLAFLLAAFSWPYVYAANALAGSDAVRFDGVAIDRWEEDGRSPTYGVYLRDARSGAVVSLRIDRHEYAALRTGDRAVCDYRRGRLGFYFRWRLGAPQACRFERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK73</accession>
    <name>A0A0S2DK73_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyoxalase_6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3707</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3707"/>
    <dbReference type="EnsemblBacteria" id="ALN59051">
        <property type="protein sequence ID" value="ALN59051"/>
        <property type="gene ID" value="GLE_3707"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3707"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3651"/>
    <dbReference type="OMA" id="MEAPTGQ"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyoxalase_6" evidence="1">
        <location>
            <begin position="9"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="126" mass="14410" checksum="4A45447B37674C42" modified="2016-02-17" version="1">MHRSRLAQLVIDCETTDPDWAAQFWAQALGCRIQALGDAADEMYRRLLMHANQPCLLVQAVPHASRVHLDIETDDVEAEVVRLERLGAARIAQVKRWWVMAAPTGQRFCVLPPQRQDFPAHSNVWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK74</accession>
    <name>A0A0S2DK74_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase</fullName>
            <ecNumber evidence="8 9">2.8.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">(Dimethylallyl)adenosine tRNA methylthiotransferase MiaB</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">tRNA-i(6)A37 methylthiotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 13" type="primary">miaB</name>
        <name evidence="14" type="ORF">FE772_17750</name>
        <name evidence="13" type="ORF">GLE_3604</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">C3</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>[sulfur carrier]-SH + AH2 + N(6)-dimethylallyladenosine(37) in tRNA + 2 S-adenosyl-L-methionine = 2-methylsulfanyl-N(6)-dimethylallyladenosine(37) in tRNA + 5'-deoxyadenosine + [sulfur carrier]-H + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:37067"/>
            <dbReference type="Rhea" id="RHEA-COMP:10375"/>
            <dbReference type="Rhea" id="RHEA-COMP:10376"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:74415"/>
            <dbReference type="ChEBI" id="CHEBI:74417"/>
            <dbReference type="EC" id="2.8.4.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="9">Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the methylthiotransferase family. MiaB subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.4.3" evidence="8 9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948411.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3604"/>
    <dbReference type="EnsemblBacteria" id="ALN58948">
        <property type="protein sequence ID" value="ALN58948"/>
        <property type="gene ID" value="GLE_3604"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3604"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3547"/>
    <dbReference type="OMA" id="CEHFHIP"/>
    <dbReference type="OrthoDB" id="397139at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035596">
        <property type="term" value="F:methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01864">
        <property type="entry name" value="tRNA_metthiotr_MiaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006463">
        <property type="entry name" value="MiaB_methiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01938">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00273">
        <property type="entry name" value="(dimethylallyl)adenosine_tRNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01061">
        <property type="entry name" value="methylthiotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00089">
        <property type="entry name" value="TIGR00089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 9 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="11">
        <location>
            <begin position="22"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="12">
        <location>
            <begin position="162"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="10">
        <location>
            <begin position="403"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN58948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW27199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="474" mass="51846" checksum="C3B9CA4EDBC08AEF" modified="2016-02-17" version="1">MTDLHPLPALPGVAPPSRPGAKKLFIETHGCQMNEYDSAKMADVLAASDGLELTTDASEADVILINTCSIREKAQEKVFSQLGRWKQHKQGERQVIIGVGGCVASQEGAAIVKRAPHVDLVFGPQTLHRLPELIRAKRETGLPQVDISFPEIEKFDRLPEPRAEGPSAFVSIMEGCSKYCSFCVVPYTRGEEVSRPFEDVLVEVAQLAAQGVREINLLGQNVNAYRGPIAGEDGASSAEVADLGLLIRTIAEIDGVDRIRFTTSHPLEFSDSLVEAYRDVPQLADYLHLPVQAGSDRILSAMKRGYTALEFKQKIRKLRAVRPNISISSDFIVGFPGETEADFEKTMKLIEDVGFDQSFSFIYSRRPGTPAADLEDTVTSEEKHARLSRLQAAINANAAKISQAMVGSVQRVLVEGPSRKNPDELTGKTENMRSVNFPAPKRLIGRFVDVTITEALSNSLRGRVRLGDDAHTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKT9</accession>
    <name>A0A0S2DKT9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DUF2007 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_19015</name>
        <name evidence="5" type="ORF">FE772_19130</name>
        <name evidence="3" type="ORF">GLE_3894</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000054">
        <property type="protein sequence ID" value="OPD62319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948628.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000054.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3894"/>
    <dbReference type="EnsemblBacteria" id="ALN59237">
        <property type="protein sequence ID" value="ALN59237"/>
        <property type="gene ID" value="GLE_3894"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62319">
        <property type="protein sequence ID" value="OPD62319"/>
        <property type="gene ID" value="BV903_19015"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3894"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3832"/>
    <dbReference type="OMA" id="EIGLCGQ"/>
    <dbReference type="OrthoDB" id="1917736at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018551">
        <property type="entry name" value="DUF2007"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09413">
        <property type="entry name" value="DUF2007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2007" evidence="2">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD62319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW27435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="90" mass="9490" checksum="C7B928578A6C9849" modified="2016-02-17" version="1">MRVVYEAAHLIDAHLVRHALEDAGIPVFLRGEALIGGMGELPLFGAVQVCVPDAAWPQADEVVQALALGEPPPPEPEPQAAMPPPAWLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKW3</accession>
    <name>A0A0S2DKW3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3949</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59291">
        <property type="protein sequence ID" value="ALN59291"/>
        <property type="gene ID" value="GLE_3949"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3949"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3886"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="486" mass="51577" checksum="873D8F7899F6AEB4" modified="2016-02-17" version="1">MSEHANDPEGGSRPPLAAFAVAALGLALTAAALTAYSAEGLAGAVRLASVRYSLGLAALAGAAVTVGAVAFLALGPLRRQREEQAERAQWRARCEDLLHAFPDGVCLIDADFIVREPVSPSLSAALRCKLWPGMDLVETLRPLLAAETVEALRAYLRQCFAARAGASAPGRNPLQEATFPGPPSRPSQWGFRFEPVRHGERVAYLLVIATDIGERQRIARELAGARMRLRAQIDGLLRACLRDGLQIRSCLGHADAALERARVRLPRLCAAVGAAEREASLRSLLQEARTIKHEAAEIELELLETPAHHLELDLLDLLESAAAARAGDEGARLTGHLELLVERIAMVRDFVVGLDARAARKNAEERTGEAGGERXXXXXXXXXDSAGGGSRTWAGGRVRGTSASARRRTGIAGGRARCTCGGRDDGVGIGGRYGGRGEGRHDAGDRADADDGRPRPRDAAKRSRADNGDAAACVRAGRRDRAGAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL36</accession>
    <name>A0A0S2DL36_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">dTDP-4-dehydrorhamnose reductase</fullName>
            <ecNumber evidence="5 7">1.1.1.133</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rfbD</name>
        <name evidence="10" type="ORF">FE772_17910</name>
        <name evidence="9" type="ORF">GLE_3640</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>dTDP-beta-L-rhamnose + NADP(+) = dTDP-4-dehydro-beta-L-rhamnose + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21796"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57510"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62830"/>
            <dbReference type="EC" id="1.1.1.133"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per monomer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Bacterial outer membrane biogenesis; LPS O-antigen biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Carbohydrate biosynthesis; dTDP-L-rhamnose biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the dTDP-4-dehydrorhamnose reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.133" evidence="5 7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948436.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3640"/>
    <dbReference type="EnsemblBacteria" id="ALN58984">
        <property type="protein sequence ID" value="ALN58984"/>
        <property type="gene ID" value="GLE_3640"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3640"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3584"/>
    <dbReference type="OMA" id="AGETTWH"/>
    <dbReference type="OrthoDB" id="1076083at2"/>
    <dbReference type="UniPathway" id="UPA00124"/>
    <dbReference type="UniPathway" id="UPA00281"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008831">
        <property type="term" value="F:dTDP-4-dehydrorhamnose reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019305">
        <property type="term" value="P:dTDP-rhamnose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009243">
        <property type="term" value="P:O antigen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005913">
        <property type="entry name" value="dTDP_dehydrorham_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491">
        <property type="entry name" value="PTHR10491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01214">
        <property type="entry name" value="rmlD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RmlD_sub_bind" evidence="8">
        <location>
            <begin position="5"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN58984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="305" mass="32662" checksum="86E3B9B41EC7C708" modified="2016-02-17" version="1">MSLGRVLVVGGDGQLGVELRRRLAADAAQVLATTRSGRLADGGACEALDLGEAEAIAPLLRRLRPDHVVNAAAYTAVDRAESEPALAQAINAVAPGRLAQACAELGIGLVHFSTDYVFDGRGQRPYREDDATAPLNVYGRSKLDGERAVAASGARHLILRTAWVYAADQGHNFLRTMLRLGGERDELRVVADQRGSPTPTWLLADAVARILERGIAEPGVRHLAAAGETTWHGFAEAIFAEAVARGLLARAPRVLPIATAEYPTPAQRPAYSVLDTRSLREEYGLELPDWREGLRVSLDGTSHNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL37</accession>
    <name>A0A0S2DL37_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Adenine phosphoribosyltransferase</fullName>
            <shortName evidence="10">APRT</shortName>
            <ecNumber evidence="5 10">2.4.2.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10 12" type="primary">apt</name>
        <name evidence="12" type="ORF">GLE_3892</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine</text>
            <dbReference type="Rhea" id="RHEA:16609"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.4.2.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.7" evidence="5 10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3892"/>
    <dbReference type="EnsemblBacteria" id="ALN59235">
        <property type="protein sequence ID" value="ALN59235"/>
        <property type="gene ID" value="GLE_3892"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3892"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3830"/>
    <dbReference type="OMA" id="KPGIVFR"/>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00646"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003999">
        <property type="term" value="F:adenine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006168">
        <property type="term" value="P:adenine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00004">
        <property type="entry name" value="Aden_phosphoribosyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005764">
        <property type="entry name" value="Ade_phspho_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01090">
        <property type="entry name" value="apt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="11">
        <location>
            <begin position="76"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN59235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="197" mass="20846" checksum="5FEA3EECDC9E7E77" modified="2016-02-17" version="1">MTRADAAGAHNPVIPSVAHAPMTDSLVPIQRLIRSVADFPKPGVTFRDVTPLLADAGGFARCIDALAEPWQGSGVQAVCGIESRGFIFGAALAQKLHAGFVPLRKPGKLPPPLVTVEYELEYGRDSLQARSDALKPGERTLIVDDVLATGGTLAAARELVERLDAVLVGASVLIELPALNGRARWSGEAPVHSLLRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL41</accession>
    <name>A0A0S2DL41_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_07455</name>
        <name evidence="4" type="ORF">FE772_18125</name>
        <name evidence="2" type="ORF">GLE_3679</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000014">
        <property type="protein sequence ID" value="OPD64592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948465.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000014.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59023">
        <property type="protein sequence ID" value="ALN59023"/>
        <property type="gene ID" value="GLE_3679"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64592">
        <property type="protein sequence ID" value="OPD64592"/>
        <property type="gene ID" value="BV903_07455"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3679"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3621"/>
    <dbReference type="OrthoDB" id="2070499at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595321" evidence="1">
        <location>
            <begin position="26"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="93" mass="10436" checksum="AF6CF2125D8A3D46" modified="2016-02-17" version="1">MKMNKYRAVGAAVLMSMVFSGAALAARHHYQVIGEGYGHDRDQAYEAASYYANRSCYLGWGESTQEETILVEEFQPSSGYWYVKLSLGCFSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL68</accession>
    <name>A0A0S2DL68_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">D9T17_08910</name>
        <name evidence="3" type="ORF">FE772_19180</name>
        <name evidence="2" type="ORF">GLE_3906</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">OH11</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000022">
        <property type="protein sequence ID" value="ROU07417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948636.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000022.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3906"/>
    <dbReference type="EnsemblBacteria" id="ALN59248">
        <property type="protein sequence ID" value="ALN59248"/>
        <property type="gene ID" value="GLE_3906"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3906"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3843"/>
    <dbReference type="OMA" id="WTRWAFP"/>
    <dbReference type="OrthoDB" id="1706598at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROU07417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="196" mass="21733" checksum="6804389BD4A3CDEF" modified="2016-02-17" version="1">MKPNTRNSLILALLAVLMVATRVNHWTPIPDASWAVFFIGGFYLRNWTRWAFPALMALAVLIDYAVISRMGISFWDHYCVSAAYWFLVPAYFAMWAGGLFVARNYKRGWSTLATAAVALLASVAVCQLLSQGSFYWISDSVQNKSVAGWAANYFEWLLPYLRTTATYVGIAAVVQAIAASASKTALPAQSDDARKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL74</accession>
    <name>A0A0S2DL74_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4093</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59435">
        <property type="protein sequence ID" value="ALN59435"/>
        <property type="gene ID" value="GLE_4093"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4093"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4035"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="226" mass="25398" checksum="6FD0D08D952712AD" modified="2016-02-17" version="1">MLHGLRVSRAALSRAADKGRDRRENSAEGHAQARSLRHQARRRSVRAPGRSPGLRVEPVERPCPRFRRRAFPCVKHSGRCGAWTRLPLRGQLRLERADRSGEQIRGATGFPFQSPDCAGDHLERAHLNSRDARASERHRQHAALFRTGPIQSSPRPRPCWRRACARSGPAPHPRSLFVFRPPARRAYATGGSFCPRSAAQRRKRGAYHFLITCVSRFLAASLTGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLD9</accession>
    <name>A0A0S2DLD9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">POTRA domain, ShlB-type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_3988</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3988"/>
    <dbReference type="EnsemblBacteria" id="ALN59330">
        <property type="protein sequence ID" value="ALN59330"/>
        <property type="gene ID" value="GLE_3988"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3988"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3925"/>
    <dbReference type="OMA" id="NIVEINV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005565">
        <property type="entry name" value="Hemolysn_activator_HlyB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013686">
        <property type="entry name" value="Polypept-transport_assoc_ShlB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08479">
        <property type="entry name" value="POTRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03865">
        <property type="entry name" value="ShlB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595798" evidence="2">
        <location>
            <begin position="29"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA_2" evidence="4">
        <location>
            <begin position="79"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="ShlB" evidence="3">
        <location>
            <begin position="241"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="572" mass="62487" checksum="4CBA50A7C681EBE5" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLK9</accession>
    <name>A0A0S2DLK9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase</fullName>
            <ecNumber evidence="7">6.3.2.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Meso-A2pm-adding enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Meso-diaminopimelate-adding enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-tripeptide synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-N-acetylmuramyl-tripeptide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">murE</name>
        <name evidence="13" type="ORF">FE772_20270</name>
        <name evidence="12" type="ORF">GLE_4135</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">C3</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + meso-2,6-diaminoheptanedioate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate</text>
            <dbReference type="Rhea" id="RHEA:23676"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
            <dbReference type="ChEBI" id="CHEBI:83905"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7 8">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="7">Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the MurCDEF family. MurE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.13" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948814.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4135"/>
    <dbReference type="EnsemblBacteria" id="ALN59477">
        <property type="protein sequence ID" value="ALN59477"/>
        <property type="gene ID" value="GLE_4135"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4135"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4077"/>
    <dbReference type="OMA" id="CFMEVSS"/>
    <dbReference type="OrthoDB" id="1861122at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008765">
        <property type="term" value="F:UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00208">
        <property type="entry name" value="MurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005761">
        <property type="entry name" value="UDP-N-AcMur-Glu-dNH2Pim_ligase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="SSF63418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01085">
        <property type="entry name" value="murE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 7 8" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 7 8" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7 8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7 8" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="9">
        <location>
            <begin position="23"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="11">
        <location>
            <begin position="110"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="10">
        <location>
            <begin position="334"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-MurNAc-L-Ala-D-Glu binding" evidence="7">
        <location>
            <begin position="154"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Meso-diaminopimelate binding" evidence="7">
        <location>
            <begin position="409"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Meso-diaminopimelate recognition motif" evidence="7">
        <location>
            <begin position="409"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="112"/>
            <end position="118"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="385"/>
        </location>
        <ligand>
            <name>meso-2,6-diaminoheptanedioate</name>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>meso-2,6-diaminoheptanedioate</name>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="464"/>
        </location>
        <ligand>
            <name>meso-2,6-diaminoheptanedioate</name>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="7">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN59477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW27626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="507" mass="53411" checksum="4C5F1B3FE7DD8C45" modified="2016-02-17" version="1">MSRSMLLSELLPDVAGIPGDLRIGGLAMDSRAVRAGDAFVAIAGFGAHGLKFVEQARASGAAAILFEPPAPDDLPAPADAIAVPGLRSRLGEMGDAFHGRPSASMRVVGVTGTNGKTSTVQLIAQAWHLLGLSCGTIGTLGAGLYGQVVPNGFTTPLVLPLHELLAGMRDAGAQAVAMEVSSHALDQGRVAGVHFDVGVFTNLTRDHLDYHGDMASYGAAKARLFGWDGLKAAAINLDDEFGRELLAQLPKRVRGIGLSSRGQAGASVRADRLSFDSRGIGFDLVVGGKAHPVASRLLGRFNVDNLLAVAGALYALEQEPATIARVLSQLEPIHGRMNRLGGDGRLPLVVIDYAHTPDALEQALASLRAHAQARLICVFGCGGERDRGKRPQMAAIAEHGADLAIVTDDNPRGEDGDVIVADILEGFRDPQRALVLRDRRAAIERAIAEAGPDDIVLVAGKGHEPYQEIHGVRHPFDDTLVARAALEARAPHMDVQVPRAQDGQERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLT3</accession>
    <name>A0A0S2DLT3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLE_4281</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4281"/>
    <dbReference type="EnsemblBacteria" id="ALN59622">
        <property type="protein sequence ID" value="ALN59622"/>
        <property type="gene ID" value="GLE_4281"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4281"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4220"/>
    <dbReference type="OMA" id="KGVCDNI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="173"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="234"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN59622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="454" mass="49268" checksum="62BCE54F1278B103" modified="2016-02-17" version="1">MPRSASARLALAVTASFLLAFVLLGIGVHYAVSAMLTQDARDLVRVDAAGLVEMYRDDGRAALLGELRDRIDADEDPDAVYALTAADGRVVAGNVALPRHHRGARWIEFTEHRADGDLRVVAQLQQLPDGTTLLTGTRTRSQDRFLGLMLRTALAALLVAATLGALIGWLTSRWVSHRLRHLDDTAERVGSGEMALRARLDGSDDAFDLLARRFNAMLDRIQDLLDGVRHATDHIAHDLRTPLTRLRNRLEELRRREPGVEAGAQLDAAIGETDQLLHSFGALLRLARIEAQPPVHDEPMLDLSDLVRDAAELYTPIAAERGIALTLDLPEPGVAGLRGDADQLFQMLVNLLDNAVKYAPADTEVGLGVQRERHAVVVRVDDRGPGIPAAERERVFDRFHRLEAHRGSPGTGLGMSLVRAIAHRHGGHIALLDNAPGLRVRVTLGEAGGQGGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM08</accession>
    <name>A0A0S2DM08_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD-dependent dehydratase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2 4">NAD-dependent epimerase/dehydratase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_04440</name>
        <name evidence="4" type="ORF">FE772_20785</name>
        <name evidence="2" type="ORF">GLE_4243</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000008">
        <property type="protein sequence ID" value="OPD65174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948899.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000008.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4243"/>
    <dbReference type="EnsemblBacteria" id="ALN59584">
        <property type="protein sequence ID" value="ALN59584"/>
        <property type="gene ID" value="GLE_4243"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65174">
        <property type="protein sequence ID" value="OPD65174"/>
        <property type="gene ID" value="BV903_04440"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4243"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4184"/>
    <dbReference type="OMA" id="RLRPFNH"/>
    <dbReference type="OrthoDB" id="955232at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="47"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD65174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="311" mass="33954" checksum="4C8ABF8EE68558CE" modified="2016-02-17" version="1">MSGANAADAPRRLLVTGGSGFVGRYVEAAVRAGDFGDYEFHTPDQGWDIRDAEAVNRAVEELRPHAVLHLAAQSFVPRSFEDPRETFEINTLGTLNLLQALKRAGFDGRLLYISSGDVYGQVAEAQMPVTEALLPAPRNPYAVSKLAAEQLCLQWQRSEGLDAIVLRPFNHIGPGQGRQFVLPALASQVAAIAQGRQAPVIEAGDIDTTRDFTDVRDIVAAYAAALRDGVSGQLYLVASGVERKVRDLLEAMCRIEGVQVEVRQDPAKLRRAEQRRMVGSAGALREATGWAPRIPMEQTLQDILLDQRNQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM74</accession>
    <name>A0A0S2DM74_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4307</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59648">
        <property type="protein sequence ID" value="ALN59648"/>
        <property type="gene ID" value="GLE_4307"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4307"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4246"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="47" mass="5161" checksum="4913A5B982C8B51C" modified="2016-02-17" version="1">MRWCATGEAQGAPAMNVGIFHWLILFVLIGGAAGTVWLISYLANRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DME2</accession>
    <name>A0A0S2DME2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Gluconolaconase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">NHL repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_21575</name>
        <name evidence="4" type="ORF">GLE_4417</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW27853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949038.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4417"/>
    <dbReference type="EnsemblBacteria" id="ALN59758">
        <property type="protein sequence ID" value="ALN59758"/>
        <property type="gene ID" value="GLE_4417"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4417"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4355"/>
    <dbReference type="OMA" id="HRVHRIA"/>
    <dbReference type="OrthoDB" id="966287at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001258">
        <property type="entry name" value="NHL_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01436">
        <property type="entry name" value="NHL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51125">
        <property type="entry name" value="NHL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242199" evidence="3">
        <location>
            <begin position="20"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="repeat" description="NHL" evidence="2">
        <location>
            <begin position="125"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="repeat" description="NHL" evidence="2">
        <location>
            <begin position="179"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW27853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="702" mass="74636" checksum="FE85CBF5D178D601" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMF1</accession>
    <name>A0A0S2DMF1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxylase family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">VOC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_22325</name>
        <name evidence="2" type="ORF">GLE_4574</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949154.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4574"/>
    <dbReference type="EnsemblBacteria" id="ALN59915">
        <property type="protein sequence ID" value="ALN59915"/>
        <property type="gene ID" value="GLE_4574"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4574"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4510"/>
    <dbReference type="OMA" id="MNICRVH"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd08352">
        <property type="entry name" value="VOC_Bs_YwkD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037478">
        <property type="entry name" value="YwkD-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="5"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="128" mass="14303" checksum="B3499BADD88D2B6C" modified="2016-02-17" version="1">MHLSAIHHVAIICADYERSRRFYVQTLGLRVIAEAWREARRSHKLDLALPDGGQIELFSFPDPPPRPSYPEACGLRHLAFRTPDLDACIAGLAAHGVAAEPVRVDEYTGRRFAFCADPDGLPIEFYEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMN5</accession>
    <name>A0A0S2DMN5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glucanase</fullName>
            <ecNumber evidence="4">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">bgc</name>
        <name evidence="7" type="ORF">FE772_21370</name>
        <name evidence="6" type="ORF">GLE_4374</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the glycosyl hydrolase 8 (cellulase D) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="A0A0S2DMN5"/>
    <dbReference type="STRING" id="69.GLE_4374"/>
    <dbReference type="EnsemblBacteria" id="ALN59715">
        <property type="protein sequence ID" value="ALN59715"/>
        <property type="gene ID" value="GLE_4374"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4374"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4313"/>
    <dbReference type="OMA" id="CRTPWRL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002037">
        <property type="entry name" value="Glyco_hydro_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019834">
        <property type="entry name" value="Glyco_hydro_8_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01270">
        <property type="entry name" value="Glyco_hydro_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00735">
        <property type="entry name" value="GLHYDRLASE8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00812">
        <property type="entry name" value="GLYCOSYL_HYDROL_F8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242582" description="Glucanase" evidence="5">
        <location>
            <begin position="34"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW27813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="414" mass="44632" checksum="DD8632EB4B57F665" modified="2016-02-17" version="1">MQQAHARPRRGGKRLALVLAAAAVLGVPLAAQAAPNYPFASHRQAYVAGTLSPSVGRAAADQSTASFYRTWKQRYLVPACKAGEYRVKASTADAYVVSEGQGYGMLITVMMAGNDPDAQALFDGLHRYNRGHPSNQNPALLAWAQDINCKNVAGADSATDGDLDIAYALLLADLQWGSGGSINYLAEARKVIAAIRSSNVNANTKLVTLGDWVDSGSPNYYNATRSSDWMLGHFRGFASKLGDSYWTGVLDAHQNLIAKMQSSYAPNTGLLPDFIVNTNTTAKPAPANFLEADTDGWYSWNAGRVPWRIGIDAAVSGDSRSRNAARKLSQWIKVKAGNNANNVRSGYKLDGTVTENYNSTFFTAPFAVAATVDTDQAWLDKLWTYMASGGTSDYYGDSVKLLSMLAVSNNWLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMV3</accession>
    <name>A0A0S2DMV3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cation diffusion facilitator family transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Cation transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_22260</name>
        <name evidence="7" type="ORF">GLE_4561</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="ALN59902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW27965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59902">
        <property type="protein sequence ID" value="ALN59902"/>
        <property type="gene ID" value="GLE_4561"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4561"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4497"/>
    <dbReference type="OMA" id="RTWGWAR"/>
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        <property type="entry name" value="Cation_efflux"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-0813">Transport</keyword>
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            <begin position="18"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW27965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="300" mass="31720" checksum="F13D4AF51C66DCA8" modified="2016-02-17" version="1">MGSGHDHGTAAIRHEKPLWWALGLTGGFLIAEVIGAFLTNSLALLSDAAHMGTDTVALMIALTAVRLSRRPADAKRSFGYARMEAMGAMANGLMLFVVAGYILYEAVGRFAKPAEIATTGMLVIASLGLAVNLIAMRLLRAGSGESLNMKGAYLEVWSDMLGSVAVIAGAIAIRYTGWAWIDPVLAVLIGLWVLPRTWTLLREAGNVLMEGVPKGIDLDAVRALLASTAGVAGVHDLHVWSLGSSTPALTAHLVVAPGTDGEALRRELTKLLDERYGIEHCTLQIENEACEGEACDAPHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMY9</accession>
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        <lineage>
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            <taxon>Gammaproteobacteria</taxon>
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    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW27869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949054.1">
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59779">
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        <property type="gene ID" value="GLE_4438"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4438"/>
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    </dbReference>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
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            <dbReference type="EMBL" id="ALN59779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="251" mass="29015" checksum="8278430249FCB1F5" modified="2016-02-17" version="1">MLITPDFVFIHMPKTGGTFIARMLQKVYGDTAVETGRKHATCDEIPEAERGKPIVSVMRSPFDRYVSQYHYGWWRTQPQEYCDPATIRADFPRYPDVGFADFVKIANRFFVNVHRGVATGYETPRLPPALAPGWHTEQFVRFYCRDSRQAFAGLTEQALQRGRAQPYEYPVEFLKTETLNDDLADLLARFGVGAAQAEAVRMHERVLPELAHETRERADADDYFDEALRDFVLRKESFLFNRFPEYRAVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN18</accession>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">GLE_4641</name>
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        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN59982">
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        <property type="gene ID" value="GLE_4641"/>
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    <dbReference type="PATRIC" id="fig|69.6.peg.4577"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="20"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="159" mass="17664" checksum="73E94EBD64F80B92" modified="2016-02-17" version="1">MNRDRLRQFESIAQLQRVRLDRAQLHAAGLRRELQRAQQACQASLTERDGLQAQWRAALDRGAGLDLAAIAGWRSLAGEAQRRCDENDAAQRQAGDAVDAFARELLRLRTQSERSDADVARERAALARKREEKLGDAALERHNALLHEATSPHAQGAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN59</accession>
    <name>A0A0S2DN59_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ABC transporter substrate-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">MCE family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Mce related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_04325</name>
        <name evidence="5" type="ORF">FE772_20670</name>
        <name evidence="3" type="ORF">GLE_4219</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000008">
        <property type="protein sequence ID" value="OPD65152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948878.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000008.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4219"/>
    <dbReference type="EnsemblBacteria" id="ALN59560">
        <property type="protein sequence ID" value="ALN59560"/>
        <property type="gene ID" value="GLE_4219"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65152">
        <property type="protein sequence ID" value="OPD65152"/>
        <property type="gene ID" value="BV903_04325"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4219"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4161"/>
    <dbReference type="OMA" id="VPGQIIV"/>
    <dbReference type="OrthoDB" id="807474at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003399">
        <property type="entry name" value="Mce/MlaD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02470">
        <property type="entry name" value="MlaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="MlaD" evidence="2">
        <location>
            <begin position="48"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD65152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW27691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="312" mass="33493" checksum="CFE7F3C47E9108E2" modified="2016-02-17" version="1">METKANYVLIGAFTIVVTLFLLLFALWAAKYSSEKSWREYAVIFNEPVTGLSEGSTVQYNGIGVGTVQQLSLAPDDPRRVIAKLRLQADAPVKTDTRAKLSLTGITGTPIIQLTGGSPNSPRLAESGNGDVPIIQTEASALQNIADTANRLVARLDQVLSDDNVQHVSKTLANIESLTGSIADQRGDLRDLIANAKKSSEQLSQTLATTNRAVESVDRELAQKLPGVIDKLDSTLTKLDSAASGANGILNDNRAAISSFANDGLAQLGPTLAELRALVRDLRRISDRLDSNPTRYLLGRDAAKEFEPEKAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNC4</accession>
    <name>A0A0S2DNC4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_04585</name>
        <name evidence="5" type="ORF">FE772_20970</name>
        <name evidence="3" type="ORF">GLE_4283</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD65200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW27747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948931.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000008.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59624">
        <property type="protein sequence ID" value="ALN59624"/>
        <property type="gene ID" value="GLE_4283"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65200">
        <property type="protein sequence ID" value="OPD65200"/>
        <property type="gene ID" value="BV903_04585"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4283"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4222"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
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        <location>
            <begin position="22"/>
            <end position="67"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="31"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD65200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW27747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="67" mass="6414" checksum="EB30C5FBE708B492" modified="2016-02-17" version="1">MNVRNVLLAAALTAFAGSAFAAAPAAAGSTAAPAAKTASHKHKKHHKASKAKAAKAAAAPEAAPASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DND7</accession>
    <name>A0A0S2DND7_LYSEN</name>
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        <submittedName>
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        </submittedName>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
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        <property type="protein sequence ID" value="ALN59901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW27964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949146.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4560"/>
    <dbReference type="EnsemblBacteria" id="ALN59901">
        <property type="protein sequence ID" value="ALN59901"/>
        <property type="gene ID" value="GLE_4560"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4560"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4496"/>
    <dbReference type="OMA" id="LGEIFMW"/>
    <dbReference type="OrthoDB" id="91817at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProt"/>
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        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="AcrB_DN_DC_subdom"/>
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        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004763">
        <property type="entry name" value="CzcA/CusA/SilA/NccA/HelA/CnrA"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="359"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="385"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="411"/>
            <end position="430"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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            <begin position="469"/>
            <end position="488"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="524"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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        <location>
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            <end position="928"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="935"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="985"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="1026"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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        </location>
    </feature>
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            <end position="1093"/>
        </location>
    </feature>
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        <location>
            <begin position="1079"/>
            <end position="1093"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010942"/>
        </source>
    </evidence>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW27964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="1093" mass="117128" checksum="680546855FE56C9F" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNE0</accession>
    <name>A0A0S2DNE0_LYSEN</name>
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        <recommendedName>
            <fullName evidence="9">Na(+)/H(+) antiporter NhaA</fullName>
        </recommendedName>
        <alternativeName>
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        </alternativeName>
    </protein>
    <gene>
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        <name evidence="10" type="ORF">GLE_4299</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>2 H(+)(out) + Na(+)(in) = 2 H(+)(in) + Na(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29251"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.</text>
    </comment>
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        <property type="protein sequence ID" value="ALN59640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW27760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4299"/>
    <dbReference type="EnsemblBacteria" id="ALN59640">
        <property type="protein sequence ID" value="ALN59640"/>
        <property type="gene ID" value="GLE_4299"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4299"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4238"/>
    <dbReference type="OMA" id="MGLMLRC"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015081">
        <property type="term" value="F:sodium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006885">
        <property type="term" value="P:regulation of pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01844">
        <property type="entry name" value="NhaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023171">
        <property type="entry name" value="Na/H_antiporter_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004670">
        <property type="entry name" value="NhaA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30341">
        <property type="entry name" value="PTHR30341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06965">
        <property type="entry name" value="Na_H_antiport_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00773">
        <property type="entry name" value="NhaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0050">Antiport</keyword>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0915">Sodium</keyword>
    <keyword evidence="8 9" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
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</entry>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
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                <person name="Hernandez I."/>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_MTAY01000012.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60252">
        <property type="protein sequence ID" value="ALN60252"/>
        <property type="gene ID" value="GLE_4911"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64721">
        <property type="protein sequence ID" value="OPD64721"/>
        <property type="gene ID" value="BV903_06715"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4911"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4841"/>
    <dbReference type="OMA" id="YDHELLC"/>
    <dbReference type="OrthoDB" id="1292067at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="13"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="204" mass="22597" checksum="01A6EC9981AA3FD4" modified="2016-02-17" version="1">MKSPHPPTLGGLLRALRARNQWTLKQLSELSGIPLSTLSKIEHDRLSLSYERLVQLSQRLNLSMGELFSAPRPAERGVTARRSIGRLRESPHIGGRNYDAYLLCAELRRKRMIPALTRIHARSLQEFGELVRTPGEEFVYVLDGAVALHTEFYDPTVLRAGESSYIDSDMGHAYVLAEGCDSATVLAVAACDDEQPLLDALAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP59</accession>
    <name>A0A0S2DP59_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4932</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60273">
        <property type="protein sequence ID" value="ALN60273"/>
        <property type="gene ID" value="GLE_4932"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4932"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4861"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="56" mass="6248" checksum="6F3D77793D7AF51B" modified="2016-02-17" version="1">MHRRCDAQHTRPFGPRVLPRSARGASAGGRPARTAIRAARRRFAGPGRGSGRRRQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPH1</accession>
    <name>A0A0S2DPH1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hydrolase, alpha/beta fold family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_5153</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5153"/>
    <dbReference type="EnsemblBacteria" id="ALN60494">
        <property type="protein sequence ID" value="ALN60494"/>
        <property type="gene ID" value="GLE_5153"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5153"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5076"/>
    <dbReference type="OMA" id="FWFTGYS"/>
    <dbReference type="OrthoDB" id="1119700at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012020">
        <property type="entry name" value="ABHD4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005211">
        <property type="entry name" value="Ab_hydro_YheT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="72"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="330" mass="36768" checksum="1894C2E5821532B1" modified="2016-02-17" version="1">MLTAADYAPPRWLRNAHVQSVLGSSPLRRRTAEQRLAAAGARTEIHLLETAGGVRLQGLHSAVPGVRPHGLVLLLHGWEGSAESNYMRLTAAQLLGRGFEVFRLNFRDHGDTHHLNEGLFHSNRLEEVVQAAQEVARRFPLRPLSVAGYSLGGNFALRLALRASEIGLPLAHAVAVCPVLDPARTMDSMETGLPMYLWYFERKWRDSLARKRDLFPSVHDFDDRTLGLRMRPLTQWMVERHTDFGTLDRYFEGYSIAGPRLARLQVPASILMAADDPVIPLDAFGELQLPPHSRLEVAPWGGHCGFLENARLDGFAERWIADRLAALAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPH2</accession>
    <name>A0A0S2DPH2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">R2K_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60072">
        <property type="protein sequence ID" value="ALN60072"/>
        <property type="gene ID" value="GLE_4731"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4731"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4665"/>
    <dbReference type="OMA" id="RMEPEMR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041261">
        <property type="entry name" value="R2K_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18299">
        <property type="entry name" value="R2K_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="R2K_2" evidence="1">
        <location>
            <begin position="85"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="253" mass="28035" checksum="2467B4FC97B6B6D1" modified="2016-02-17" version="1">MFRIAYLEERHNVLELEERLVAEALAPRGVEIRRYTRKHIDRRSLPLDEDCFVMGTAPSVHGAMKQLGIPVPAPHDYPQALQPWLHRRVWRETLGAVESWVSEGAAGSLFVKPADRLKTFTGRVFSHPGDLYFLGGGSRRQSVWCSTPVGWRSEFRAYVIGADVIALDHYAGDPDVRPCERAIAEAVRAYHDSGEAPAGYGIDFGVLDNGNTALVEANDGYALGAYGIAADRYAELLMARWAQLMATRLPVGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPU8</accession>
    <name>A0A0S2DPU8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protease 4</fullName>
            <ecNumber evidence="3">3.4.21.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Endopeptidase IV</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Protease IV</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Signal peptide peptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">sppA</name>
        <name evidence="8" type="ORF">FE772_23605</name>
        <name evidence="7" type="ORF">GLE_4859</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase S49 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949368.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4859"/>
    <dbReference type="EnsemblBacteria" id="ALN60200">
        <property type="protein sequence ID" value="ALN60200"/>
        <property type="gene ID" value="GLE_4859"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4859"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4790"/>
    <dbReference type="OMA" id="DPKGQYL"/>
    <dbReference type="OrthoDB" id="1318587at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07023">
        <property type="entry name" value="S49_Sppa_N_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004634">
        <property type="entry name" value="Pept_S49_pIV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004635">
        <property type="entry name" value="Pept_S49_SppA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002142">
        <property type="entry name" value="Peptidase_S49"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01343">
        <property type="entry name" value="Peptidase_S49"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001217">
        <property type="entry name" value="Protease_4_SppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00705">
        <property type="entry name" value="SppA_67K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00706">
        <property type="entry name" value="SppA_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
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</entry>
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            <ecNumber evidence="6">2.3.1.47</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">7-keto-8-amino-pelargonic acid synthase</fullName>
            <shortName evidence="6">7-KAP synthase</shortName>
            <shortName evidence="6">KAPA synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">8-amino-7-ketopelargonate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">bioF</name>
        <name evidence="10" type="ORF">BV903_05595</name>
        <name evidence="9" type="ORF">GLE_0062</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">B25</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>6-carboxyhexanoyl-[ACP] + H(+) + L-alanine = (8S)-8-amino-7-oxononanoate + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:42288"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9955"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78846"/>
            <dbReference type="ChEBI" id="CHEBI:149468"/>
            <dbReference type="EC" id="2.3.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Cofactor biosynthesis; biotin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.47" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000010">
        <property type="protein sequence ID" value="OPD64962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945766.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0062"/>
    <dbReference type="EnsemblBacteria" id="ALN55421">
        <property type="protein sequence ID" value="ALN55421"/>
        <property type="gene ID" value="GLE_0062"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64962">
        <property type="protein sequence ID" value="OPD64962"/>
        <property type="gene ID" value="BV903_05595"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0062"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.68"/>
    <dbReference type="OMA" id="HYHASGI"/>
    <dbReference type="OrthoDB" id="479874at2"/>
    <dbReference type="UniPathway" id="UPA00078"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008710">
        <property type="term" value="F:8-amino-7-oxononanoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01693">
        <property type="entry name" value="BioF_aminotrans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004723">
        <property type="entry name" value="AONS_Archaea/Proteobacteria"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022834">
        <property type="entry name" value="AONS_Proteobacteria"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00858">
        <property type="entry name" value="bioF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4 6" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="8">
        <location>
            <begin position="46"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="6">
        <location>
            <begin position="113"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="358"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6 7">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR604723-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN55421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD64962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="410" mass="44038" checksum="914597A2688C5B17" modified="2016-02-17" version="1">MSSQRILWRDRVHAAQAQRVAAARSRTHRAVSHRDGARCEVDGRSLVNFCGNDYLGLSQHFAVINAFQDAASREGTGGIASHLVCGHHAQHEALERELADWLESPRALLFGSGFMANIAAVQGLLGEEDVCVQDRLNHASLIDAARLAGCRLRRYPHADPEGAIRQLRNVPDGLAMLATDGVFSMDGDIAPLRDLALVARAQKAVLYVDDAHGVGVTGPDGRGTVAAARLSVQEVPLQLATFGKALGSYGAALHGDAELIGHLAETARSHLYTTALPPAQAAATRAAIKLARNDHWRREKLADLTSHFRERAIQLGLELLPSGTPIQPVMCGDDRRALAMAQALEQQGYWVAAIRPPTVPEGRARLRVTFSALHTREQVDGLIEALARAAERVAIERADEAAMAAVGAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAM1</accession>
    <name>A0A0S2DAM1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0247</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55606">
        <property type="protein sequence ID" value="ALN55606"/>
        <property type="gene ID" value="GLE_0247"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0247"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.249"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="143" mass="15061" checksum="545748121B8603CF" modified="2016-02-17" version="1">MDKRILLGCLGGAGMLLLFGLLTKLFGLDARQAIDTGIGPLPLIDILAALVSMFLGGALARHARFRWIALLLPSAMWALTLFAVVAMAQPDSPPPMRSIGAALKYNALAIALTLAAAFAGALLGERFGRKRFGALGSDGLMRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-08-12" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAQ1</accession>
    <name>A0A0S2DAQ1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_0269</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55627">
        <property type="protein sequence ID" value="ALN55627"/>
        <property type="gene ID" value="GLE_0269"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0269"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.268"/>
    <dbReference type="OMA" id="IVRAAYV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.550">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001129">
        <property type="entry name" value="Membr-assoc_MAPEG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
        <property type="entry name" value="MAPEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="SSF161084"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595168" evidence="5">
        <location>
            <begin position="27"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN55627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="131" mass="14022" checksum="D58FE08C7C94DB8B" modified="2016-02-17" version="1">MSMTIAYWCLLAAALLPYLWTSLAKANGQRYDNRDPRGWQARQDNPRSKAAYAAHLNAFEAFPAFAAGVLGAQMAGVDTGWIDVLALAFIAFRVLHGVFYIAGKASLRSAVWAGGFACTVALLVLAALATI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAR3</accession>
    <name>A0A0S2DAR3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA repair protein RadC</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="10">JAB domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">radC</name>
        <name evidence="9" type="ORF">BV903_12955</name>
        <name evidence="10" type="ORF">FE772_02080</name>
        <name evidence="8" type="ORF">GLE_0250</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the UPF0758 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000032">
        <property type="protein sequence ID" value="OPD63529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945903.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0250"/>
    <dbReference type="EnsemblBacteria" id="ALN55609">
        <property type="protein sequence ID" value="ALN55609"/>
        <property type="gene ID" value="GLE_0250"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63529">
        <property type="protein sequence ID" value="OPD63529"/>
        <property type="gene ID" value="BV903_12955"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0250"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.252"/>
    <dbReference type="OMA" id="AMPDYEL"/>
    <dbReference type="OrthoDB" id="1833204at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08071">
        <property type="entry name" value="MPN_DUF2466"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025657">
        <property type="entry name" value="RadC_JAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001405">
        <property type="entry name" value="UPF0758"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020891">
        <property type="entry name" value="UPF0758_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30471">
        <property type="entry name" value="PTHR30471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04002">
        <property type="entry name" value="RadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00608">
        <property type="entry name" value="radc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01302">
        <property type="entry name" value="UPF0758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="7">
        <location>
            <begin position="102"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN55609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD63529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW24645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="224" mass="24279" checksum="EA82B3C5C8464ED1" modified="2016-02-17" version="1">MRIQEWPSAERPREKLLARGATTLSDAELLALILGSGVRGHDAVGTARRLLNEHGPLHALLEQPPARLLRMRGIGKARACALKAALELAARSQMAELERGSAVTDPPSAGRYLAQKLRGRPHEVFAALFLNSRHGVIGYEELFQGTVDGAEVHPREVVRQALQHNAAAVIVGHNHPSGNAEPSPADRAVTQRLKQALALIDVRLLDHFVIGDGKPVSMAMRGWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAX5</accession>
    <name>A0A0S2DAX5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_0327</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0327"/>
    <dbReference type="EnsemblBacteria" id="ALN55685">
        <property type="protein sequence ID" value="ALN55685"/>
        <property type="gene ID" value="GLE_0327"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0327"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.324"/>
    <dbReference type="OMA" id="TFAATWL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN55685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="265" mass="26662" checksum="2DB67DC81F5B207D" modified="2016-02-17" version="1">MAIWLVFLVLGAIAGVLAGLLGVGGGLVLVAALAWIAPAFGIPQEAAMHTALASSLASIVLTATASARAHAKRGSVLWPTVRWMVPGLIVGGWLGSWFAVRIDGEWLRWIVAGYCLIAAAQLLFGKPRAALGEDAPAPQGAAMSGAGVGIGAVSAVVGIGGGSMTVPLLVWRGVAPVRAVGTSSACGVAIGLASAIGYAFNAPPGALPHYAIGYVYLPAAIGVALASVLAAPYGTRLAHRLHGDTLKRVFATFLFLVALSLLLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAX9</accession>
    <name>A0A0S2DAX9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">EEP domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Endonuclease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Endonuclease/exonuclease/phosphatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_25500</name>
        <name evidence="4" type="ORF">FE772_02460</name>
        <name evidence="2" type="ORF">GLE_0331</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000121">
        <property type="protein sequence ID" value="OPD61086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945958.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000121.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0331"/>
    <dbReference type="EnsemblBacteria" id="ALN55689">
        <property type="protein sequence ID" value="ALN55689"/>
        <property type="gene ID" value="GLE_0331"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61086">
        <property type="protein sequence ID" value="OPD61086"/>
        <property type="gene ID" value="BV903_25500"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0331"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.328"/>
    <dbReference type="OMA" id="RYHHYLT"/>
    <dbReference type="OrthoDB" id="1387978at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="252" mass="27307" checksum="F04692D4AE9FDB09" modified="2016-02-17" version="1">MTTRRLRLLSANIQAGSSTRRYSDYATRSWSHVLPAGNKRGSLDTIAQLAGEHDIVGLNESDPGSLRSGFTNQTHYLAQRAGFDYWSHQPNRRVGNVASSANGLLSRLEPREVVDHPLPGRIAGRGVLVAHYGNGDDGLTVAVAHLSLGAGSRASQLAFIAELLHDHPHAVLMGDFNCSADSPEMQALFRDTRLQRPADILPTFPSWRPQRAIDHILLGDGLGYIAAKAMPAAQSDHLALSLELDVPDDALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAZ5</accession>
    <name>A0A0S2DAZ5_LYSEN</name>
    <protein>
        <submittedName>
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        </lineage>
    </organism>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10 12">YC36</strain>
        </source>
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        <subcellularLocation>
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        </subcellularLocation>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN55698">
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        </location>
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        <source>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
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            <dbReference type="Pfam" id="PF07715"/>
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    </evidence>
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            <dbReference type="EMBL" id="ALN55698.1"/>
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            <dbReference type="EMBL" id="QCW24711.1"/>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
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        <source>
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    </evidence>
    <sequence length="935" mass="102324" checksum="387A05E711097033" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
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        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="112" mass="12197" checksum="BAED2C2FDE522394" modified="2016-02-17" version="1">MKMVMAVIKPFKLDDVREALAEAGVAGITATEVKGFGRQKGHTELYRGAEYVVDFLPKIKLEVAVTDDQVETVVEAIMKAAGTGKIGDGKIFVWDLERAVRIRTGEMDGDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB56</accession>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24754.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="586" mass="63226" checksum="ED76F7A4B8A22CFE" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBA9</accession>
    <name>A0A0S2DBA9_LYSEN</name>
    <protein>
        <submittedName>
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        <submittedName>
            <fullName evidence="7">Transporter, major facilitator superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
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    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW24806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55822">
        <property type="protein sequence ID" value="ALN55822"/>
        <property type="gene ID" value="GLE_0464"/>
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    <dbReference type="KEGG" id="lez:GLE_0464"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.460"/>
    <dbReference type="OMA" id="IMDFMVM"/>
    <dbReference type="OrthoDB" id="1384345at2"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="MFS_dom"/>
    </dbReference>
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        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
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        <property type="match status" value="2"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="101"/>
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    </feature>
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        <location>
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            <end position="160"/>
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            <end position="187"/>
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            <end position="241"/>
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            <begin position="253"/>
            <end position="270"/>
        </location>
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        <location>
            <begin position="12"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN55822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW24806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="421" mass="44679" checksum="38EFF41BD99A5F59" modified="2016-02-17" version="1">MYSIDPTRERRLLWLLMLTQFTLIMDFMVMMPLGPQIMRALHISPAQFAAAVSAYSICGGLSGLLAATYIDRFDRRKLLLAMYALFALSNLACALAGSYELLLASRAFAGVSGGVLGSIIMAIIADVIPAQRRGAATGTVMTAFAVASVIGVPVGILLGAHSRWSAPFWLLVALSLLIWLAGARVVPPLDQHLSRQREPLARALPNLIGLFANARHLNAFALTLMLTTSQMLVIPFISPMLVANHGIEPSQLSWMYMAGGVAAFFTSRLIGRLADRHGKQRVYRIAVAVSLLPVLFVTHLPAVGFLAMLLFFPFFMVSMNGRMVPLQALQTTVPQPQQRGAFLSANSAVMSLGTGLGAWLGGLMLSTDASGHIAGYGTVGWVAAGLALCSALWVGRVSAADAPAVATATESAQADARGDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBK4</accession>
    <name>A0A0S2DBK4_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">Peptidase, S41 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_03495</name>
        <name evidence="3" type="ORF">GLE_0553</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_0553"/>
    <dbReference type="EnsemblBacteria" id="ALN55911">
        <property type="protein sequence ID" value="ALN55911"/>
        <property type="gene ID" value="GLE_0553"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0553"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
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    </dbReference>
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    </dbReference>
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            <dbReference type="Pfam" id="PF03572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
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            <dbReference type="EMBL" id="QCW24875.1"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="503" mass="53998" checksum="DA6FAA7569B67B77" modified="2016-02-17" version="1">MRACRLSLLVAAALSVAASPCAAAAFDPAPWRQDYAQLKQALEREYANLAWFASPQGGVDLPALDRATVRALDGAENDAQAERALRDFVAGFGDGHFSFVPSLQPPAAEPVAAPPPADARRLDPAAGCAALGYDGGDARVPFSLPFESLPGFRLLDDGIAGPFRSGLMVAAQGARIGVVRLKEFSRESYPSLCLAAWADPEVVRAGDAQAWRSRLRARIDDDWYGALEAQLKRLAALGAQALIVDVGRNGGGDDSGDIATRLFTRKPLHSSPLLVSQSPTAAGYLDEQLDNLAQARGFGPDAQATQALDRQTERLRAARTDAREGRCDLSWVWRERRDWNGGHCRRLVEAGSAGGPLDNLPAGAYGNARVAKRLHWPIQMDDHWGAWDGPLYVLTDARTFSAAEMFAATLRNNGVARTLGQRTGGDGCGFMLSVEPLTLQRSRLRLRMPNCVRLRSDGSDEVAGIAPDLPLPPREGENARARAQRAIAAVVADWPTHSGDASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBP4</accession>
    <name>A0A0S2DBP4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_02760</name>
        <name evidence="2" type="ORF">GLE_0394</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55752.1"/>
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    </dbReference>
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        <property type="protein sequence ID" value="QCW24750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0394"/>
    <dbReference type="EnsemblBacteria" id="ALN55752">
        <property type="protein sequence ID" value="ALN55752"/>
        <property type="gene ID" value="GLE_0394"/>
    </dbReference>
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    <dbReference type="OMA" id="HICVYDK"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242263" evidence="1">
        <location>
            <begin position="22"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="96" mass="10333" checksum="6A76C2D73F508538" modified="2016-02-17" version="1">MNKALLIAGFFCAFFATNASASSNDAWAEFRKDVDKACRILLGPQPKNAQVTVKVDPFGTESYGAALVTVSAGKQKSQRICIYDKKTNKAELTSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBY4</accession>
    <name>A0A0S2DBY4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0609</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55967">
        <property type="protein sequence ID" value="ALN55967"/>
        <property type="gene ID" value="GLE_0609"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0609"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.601"/>
    <dbReference type="OMA" id="MAGAWIK"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="318" mass="34861" checksum="3C98A0448E92B054" modified="2016-02-17" version="1">MAFKQRYVVASIDLDKSRDARLQAAGELLAGERFEVELRKWDGQPAQVLVVGTETSASRMAVDTALRSGVPVVRIGRLPWDPETVRSLDLYAEPDELSACLRERLDALAPADARAEPVDAAAAPFLRQLLAASADGVCLLERGLFRLVVDFAGARLHMLRRMPYPALIAEALAPNWFVTPLSPRRYSEEFAQDVTASYPLESVLWDIALAHDAPIADVPADRALRLRAWPLLSANALPTHWLLPLSCLLERAWALPQLAQATATSALELERMYAAVLASGLADAEAAAPERRRAHDAQAPGLLRRLARRFGLNLGRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC29</accession>
    <name>A0A0S2DC29_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946147.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
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        <property type="protein sequence ID" value="ALN55949"/>
        <property type="gene ID" value="GLE_0591"/>
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    <dbReference type="KEGG" id="lez:GLE_0591"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.583"/>
    <dbReference type="OrthoDB" id="1087314at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
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        <location>
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            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <end position="233"/>
        </location>
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        <location>
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        </location>
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        <location>
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            <end position="322"/>
        </location>
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        <location>
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        </location>
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        <location>
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            <end position="388"/>
        </location>
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        <location>
            <begin position="400"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="453"/>
            <end position="473"/>
        </location>
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        <location>
            <begin position="485"/>
            <end position="504"/>
        </location>
    </feature>
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        <location>
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            <end position="536"/>
        </location>
    </feature>
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        <location>
            <begin position="543"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="687" mass="72458" checksum="1E20C20DFA097FC8" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC53</accession>
    <name>A0A0S2DC53_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    <organism evidence="2 3">
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="233" mass="24504" checksum="5945463F9D77E972" modified="2016-02-17" version="1">MNADKEAADAGDLAGGYEEVQGVLVAQDADGGWRYRARAPGLARGPDGRAQFTLVGAGAITMLALTASWGVPAATLDAVRAELAARAQLPAAQLGLAPAPVEVGTVRLLLGDGAGGFEELAKAQSSGVPPYHAAFNVMLDAERADKVRKALGGERGWLQLRYEVRDGFEPRRSSDARSEESLAVDVSVRDAQGEAGVSARIDYSERIEADSGRGEPRERSYSADAVDWGLPKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCD4</accession>
    <name>A0A0S2DCD4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">GLE_0785</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946298.1">
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56143">
        <property type="protein sequence ID" value="ALN56143"/>
        <property type="gene ID" value="GLE_0785"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0785"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.774"/>
    <dbReference type="OrthoDB" id="1918655at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="120" mass="12857" checksum="5B034FEAC3FC9F22" modified="2016-02-17" version="1">MHPSEFSAESGAPDPHVQHIDCSNNAAFVLRFVVQRLDGGRAISQSHRVGPFHSGQTRRVDLSALRFHGQPLEVGDRVRLRVGAVGGVRRNGPDVAYAPNGETAVFSVRGTTLAFSIGQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCI7</accession>
    <name>A0A0S2DCI7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Methyltransferase 12</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_19645</name>
        <name evidence="4" type="ORF">FE772_05105</name>
        <name evidence="2" type="ORF">GLE_0887</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000057">
        <property type="protein sequence ID" value="OPD62207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946371.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000057.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0887"/>
    <dbReference type="EnsemblBacteria" id="ALN56245">
        <property type="protein sequence ID" value="ALN56245"/>
        <property type="gene ID" value="GLE_0887"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62207">
        <property type="protein sequence ID" value="OPD62207"/>
        <property type="gene ID" value="BV903_19645"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0887"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.876"/>
    <dbReference type="OMA" id="IHDQAHP"/>
    <dbReference type="OrthoDB" id="1213908at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltranfer_dom" evidence="1">
        <location>
            <begin position="177"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="357" mass="39420" checksum="0F3FF32E57E2DFFF" modified="2016-02-17" version="1">MADGNAIDTDKVEKFSARIMEDYGNTLRGAMLYIGDKVGLFKALWRLGAVTQEELARDTGLNARYLREWLGSMVTGGYLDYDPQARRYRLPDEFAPVLADEDSPYFAGGILQLSVPFVSMAPRIAEAFRNGGGAPEEAYPLETWQGMERMTMPWYKHHLVQRWIPSLDGVEDKLRAGGTVMDFGCGSGLAAITMALAYPKSRVVGCDFHLPSIERARANAVAAGVADRVSFEVADSDVLVGQTFDFVTTFVVIHDAADPQQMLRDLRAATADDGTYLMVELNLSEELHENMNLFGRVMYPQSTLYCMTCSLSHDGAGLGAFMGEKRARAMASEAGFGRFRKVPSERPPLPALFELRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCW6</accession>
    <name>A0A0S2DCW6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0988</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946443.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56346">
        <property type="protein sequence ID" value="ALN56346"/>
        <property type="gene ID" value="GLE_0988"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0988"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.976"/>
    <dbReference type="OrthoDB" id="2049181at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="223" mass="22885" checksum="5B72F92F0B5A512D" modified="2016-02-17" version="1">MSLEPGLFVPTRADALIRGQRKVEAIKAVLDANPGASLRAAKDAVEARTDALLAGSAASLSSPAGEARETAGLPAAALEALQRGQIIEAIKLVRLAHDVDLRTAKQRVEAHLRGDVGADVGTVASQPDAAAASAPGELPADVASLLRGGDRGAAWQLLERKYGATATEALRRIGDHEIARKRGGRGGAAAAGSTVMRGGDRGKLALWALLAAFAALAVAWVLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCY1</accession>
    <name>A0A0S2DCY1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PHP C-domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1010"/>
    <dbReference type="EnsemblBacteria" id="ALN56368">
        <property type="protein sequence ID" value="ALN56368"/>
        <property type="gene ID" value="GLE_1010"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1010"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.998"/>
    <dbReference type="OMA" id="DWRYRAR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594945" evidence="2">
        <location>
            <begin position="26"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="525" mass="55572" checksum="93D50F5B3DDB4C72" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCZ7</accession>
    <name>A0A0S2DCZ7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">tRNA-dihydrouridine synthase B</fullName>
            <ecNumber evidence="10">1.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10 14" type="primary">dusB</name>
        <name evidence="15" type="ORF">FE772_05830</name>
        <name evidence="14" type="ORF">GLE_1048</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">C3</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 10 11">Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 10">
            <text>a 5,6-dihydrouridine in tRNA + NAD(+) = a uridine in tRNA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:54452"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13887"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>a 5,6-dihydrouridine in tRNA + NADP(+) = a uridine in tRNA + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:23624"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13887"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 10 11">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the Dus family. DusB subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the dus family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.-" evidence="10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946488.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1048"/>
    <dbReference type="EnsemblBacteria" id="ALN56406">
        <property type="protein sequence ID" value="ALN56406"/>
        <property type="gene ID" value="GLE_1048"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1048"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1037"/>
    <dbReference type="OMA" id="RPWLFAD"/>
    <dbReference type="OrthoDB" id="1710586at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02042">
        <property type="entry name" value="DusB_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001269">
        <property type="entry name" value="DUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032887">
        <property type="entry name" value="DusB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024036">
        <property type="entry name" value="tRNA-dHydroUridine_Synthase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004652">
        <property type="entry name" value="tRNA_dU_NifR3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006621">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00737">
        <property type="entry name" value="nifR3_yhdG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 10 11" id="KW-0288">FMN</keyword>
    <keyword evidence="10" id="KW-0521">NADP</keyword>
    <keyword evidence="9 10 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 10 11" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="10" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Dus" evidence="13">
        <location>
            <begin position="13"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10 12">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="16"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="200"/>
            <end position="202"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="224"/>
            <end position="225"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00002790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR006621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN56406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW25248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="332" mass="35974" checksum="841DA4CB8E505798" modified="2016-02-17" version="1">MRIGPHSIAPRVILAPMAGVTDKPFRVLCKRLGAGLCVSEMTTSDPRFWTTAKSRHRMDHAGEPAPISVQIAGTVPRVMAEAARYNVDHGAQIVDINMGCPAKKVCNAWAGSALMREPELVAQILEAVVAAVDVPVTLKIRTGWDHDQRNAPLIARIAEQSGIAALAVHGRTRDQQYTGVAEYDTIAAIKAQLSIPVIANGDIDSPRKAAFVLAHTGCDAVMVGRAAQGRPWIFGEIAHFLEHGEERAPPSLAQVREILLGHLEHLHAFYGEVSGVRIARKHLGWYAKDRPENAAFRAVVNRAESAEQQLRLTRDYFDALVAGVVPELPAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD49</accession>
    <name>A0A0S2DD49_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DUF4097 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_06060</name>
        <name evidence="4" type="ORF">GLE_1102</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946526.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1102"/>
    <dbReference type="EnsemblBacteria" id="ALN56460">
        <property type="protein sequence ID" value="ALN56460"/>
        <property type="gene ID" value="GLE_1102"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1102"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1089"/>
    <dbReference type="OMA" id="QFDIETH"/>
    <dbReference type="OrthoDB" id="731668at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025164">
        <property type="entry name" value="DUF4097"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13349">
        <property type="entry name" value="DUF4097"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242140" evidence="2">
        <location>
            <begin position="33"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4097" evidence="3">
        <location>
            <begin position="126"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="315" mass="33165" checksum="31FAB8098F7D5A02" modified="2016-02-17" version="1">MMSAAFRHRSALRACSGSLLALALGAALPAFASTPINESRPLDGLGSVEIDNVKGSIQVRVWDRPEVKIEGELGDGVERLQIEGDRQQLSIKVRYPNRGSGIGFLAGGDKSEPTDLRITVPLRAKLDIDAVSADVDVTGVASRELKIESVSGDVIVAGAPREAEIESVSGDLRLTLNSPKVSAQTVSGDLDLRGRLSGEVSVESVSGRVELAAHESRLYKISGESVSGDLRIDAALADGGEIGLKTVSGDVRLRLPRGLSAVVRGESFSGDLRAPDAQIQRPKHGPGSSFEQRYGSGAGRVRMETFSGDASLDLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDA8</accession>
    <name>A0A0S2DDA8_LYSEN</name>
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        <recommendedName>
            <fullName evidence="6">GDT1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BV903_03855</name>
        <name evidence="9" type="ORF">FE772_05865</name>
        <name evidence="7" type="ORF">GLE_1057</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GDT1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000007">
        <property type="protein sequence ID" value="OPD65238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946494.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1057"/>
    <dbReference type="EnsemblBacteria" id="ALN56415">
        <property type="protein sequence ID" value="ALN56415"/>
        <property type="gene ID" value="GLE_1057"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65238">
        <property type="protein sequence ID" value="OPD65238"/>
        <property type="gene ID" value="BV903_03855"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1057"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1046"/>
    <dbReference type="OMA" id="PDKMDDD"/>
    <dbReference type="OrthoDB" id="2050363at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001727">
        <property type="entry name" value="Gdt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608">
        <property type="entry name" value="PTHR12608"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01169">
        <property type="entry name" value="UPF0016"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN56415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD65238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW25255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="196" mass="20880" checksum="7A63400ADF0EA532" modified="2016-02-17" version="1">MDLSHFPAWVVATAVSTGTVALAEIGDKTQLLALLLAARFRKPVPIILGILLATLLNHALAAWFGTLVAAFLKPEVLRWVVAASFLAVALWTLKPDQLDEGETQFSARGAFIATTIAFFFAEIGDKTQVATVLLATRYEPLWAVIVGTTVGMLLANVPVALLGARFADRLPLKTARFVAAAVFAALALWVAIRGIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDL9</accession>
    <name>A0A0S2DDL9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">GNAT family N-acetyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_09890</name>
        <name evidence="4" type="ORF">FE772_06780</name>
        <name evidence="2" type="ORF">GLE_1255</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
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    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD64178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946633.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1255"/>
    <dbReference type="EnsemblBacteria" id="ALN56612">
        <property type="protein sequence ID" value="ALN56612"/>
        <property type="gene ID" value="GLE_1255"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64178">
        <property type="protein sequence ID" value="OPD64178"/>
        <property type="gene ID" value="BV903_09890"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1255"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1239"/>
    <dbReference type="OMA" id="RAGWTTE"/>
    <dbReference type="OrthoDB" id="2055010at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
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    <dbReference type="Pfam" id="PF00583">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
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        <location>
            <begin position="6"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="180" mass="20007" checksum="D3A19240E5917740" modified="2016-02-17" version="1">MSLDALTFRPATLADTDAVVALVESAYRGDSGRRGWTTESDLLDGRRTGADEIHAVLAKPQNMILLAELDDGSGPRLLACAHIAIEDGAGYFGMFSVDPGLQNGGIGKRVLAQAERIVREQWQTPTMRMTVINVREELIQYYVRRGYLRTGRFKPFPYGDARFGLPKRDDLSFEVLEKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDR3</accession>
    <name>A0A0S2DDR3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1269</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56626">
        <property type="protein sequence ID" value="ALN56626"/>
        <property type="gene ID" value="GLE_1269"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1269"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="86" mass="9560" checksum="09964C23199A23B5" modified="2016-02-17" version="1">MRADAAKCRAGKHGRPRRDTASSSLDERAAQRFCGRASGPMPDCCREAFSHNVRLSWEGLQARCSRFRSPHPFKPRSPPRPQAAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDT0</accession>
    <name>A0A0S2DDT0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Flagellar hook-length control protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_20730</name>
        <name evidence="4" type="ORF">FE772_06835</name>
        <name evidence="2" type="ORF">GLE_1267</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000064">
        <property type="protein sequence ID" value="OPD61988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946642.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000064.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56624">
        <property type="protein sequence ID" value="ALN56624"/>
        <property type="gene ID" value="GLE_1267"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61988">
        <property type="protein sequence ID" value="OPD61988"/>
        <property type="gene ID" value="BV903_20730"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1267"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1251"/>
    <dbReference type="OMA" id="PANCWNP"/>
    <dbReference type="OrthoDB" id="1813067at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0969">Cilium</keyword>
    <keyword evidence="4" id="KW-0282">Flagellum</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594749" evidence="1">
        <location>
            <begin position="25"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="159" mass="16993" checksum="B2CF04180B9B9AB3" modified="2016-02-17" version="1">MDVRAIRIAACTLALSLIAFSAVAAGGKGVTWRKAGHANGVDRVACFSPECDAYQGDTVCSARLPVLCLNQDGAPSPVPTDFYNGWAKGNIALSRAVRGDSFKSRGEADAFCRAEFGPGYRMASHHDGDGGWGWQAYGNIDATTRFWITVIDQPSSCWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDT8</accession>
    <name>A0A0S2DDT8_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Ferritin-like domain-containing protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">FE772_07140</name>
        <name evidence="1" type="ORF">GLE_1340</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
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            <taxon>Proteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946700.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1340"/>
    <dbReference type="EnsemblBacteria" id="ALN56697">
        <property type="protein sequence ID" value="ALN56697"/>
        <property type="gene ID" value="GLE_1340"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1340"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1322"/>
    <dbReference type="OMA" id="WRFAGMP"/>
    <dbReference type="OrthoDB" id="1291114at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007402">
        <property type="entry name" value="DUF455"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011197">
        <property type="entry name" value="UCP012318"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04305">
        <property type="entry name" value="DUF455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF012318">
        <property type="entry name" value="UCP012318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="274" mass="30325" checksum="A555F6EE72E996E9" modified="2016-02-17" version="1">MTAIPATLFDAARACLDAATPEAKVELTFACASAFARGELATPDDAPPPEPIRMPGRPAKPALVHPRELPKRGFGTAEGRAAFVHAIAHIEFNAIDLGWDAVYRFRGLPAQFYADWVGVANDEARHFQLLRDRLRELGYDYGDFDAHNGLWEMAEKTAHDGLARMALVPRVLEARGLDVTPGMIVKLRSIGDEATVAILDTILREEVGHVAAGSRWFRWYCARAGVDPNPRFRELLAEYARAVLYGPFNFDARSAAGFDDEELRMLEAFANTRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEA6</accession>
    <name>A0A0S2DEA6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946654.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1280"/>
    <dbReference type="EnsemblBacteria" id="ALN56637">
        <property type="protein sequence ID" value="ALN56637"/>
        <property type="gene ID" value="GLE_1280"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1280"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1263"/>
    <dbReference type="OMA" id="GYGCACA"/>
    <dbReference type="OrthoDB" id="1757706at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025145">
        <property type="entry name" value="DUF4087"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13316">
        <property type="entry name" value="DUF4087"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595394" evidence="1">
        <location>
            <begin position="29"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="137" mass="14753" checksum="CBE727B48855C41C" modified="2016-02-17" version="1">MARHGRSLLSPRFAVALAAALLAGHAAAAAKPETRCGWFINPTPGNAWLIDPDAQWTVGLQGGHQAEGPWPEPPSEKDWVKHEGDPRGYGYGCACLKVVTGFDHSIVRILSAKGKPLAQCRRDRALTGLEPDYASDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEF6</accession>
    <name>A0A0S2DEF6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine triad nucleotide-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Histidine triad nucleotide-binding protein 2 (Hint-2)(Hint-3)</fullName>
            <ecNumber evidence="3">3.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_08705</name>
        <name evidence="3" type="ORF">GLE_1679</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.-.-.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946971.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1679"/>
    <dbReference type="EnsemblBacteria" id="ALN57035">
        <property type="protein sequence ID" value="ALN57035"/>
        <property type="gene ID" value="GLE_1679"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1679"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1657"/>
    <dbReference type="OMA" id="SDCLFCK"/>
    <dbReference type="OrthoDB" id="1934382at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019808">
        <property type="entry name" value="Histidine_triad_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23089">
        <property type="entry name" value="PTHR23089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00332">
        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00892">
        <property type="entry name" value="HIT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="2">
        <location>
            <begin position="6"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="117" mass="12928" checksum="277C8BEC33E4B766" modified="2016-02-17" version="1">MTDPTIFGKIIRRELPADIVYEDDDLIAFRDIAPQAPVHVLFVPKTPIATLNELKPEQAAVVGKLAYAAAQYAKREGFAEDGYRVVMNCNEHGGQTVFQLHLHLLAGDPLGRFGTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEF8</accession>
    <name>A0A0S2DEF8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1596</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56953">
        <property type="protein sequence ID" value="ALN56953"/>
        <property type="gene ID" value="GLE_1596"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1596"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1576"/>
    <dbReference type="OMA" id="ECNDYLA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595406" evidence="2">
        <location>
            <begin position="18"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="147" mass="14245" checksum="C5ADDBD17F42421E" modified="2016-02-17" version="1">MKVKVLFLAAAVTLALAACNKPADKPADAAPAADAAAAPAGDAAAPAPAATDAAPAAPADAAAPAAAPTAASVGVPECDDYLTKVQACLTDKVPAEQRAGLEGALEQSRTAWTQAASTPQGKAALASACKTALEQSKAQYSAMGCTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEI2</accession>
    <name>A0A0S2DEI2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1572</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56929">
        <property type="protein sequence ID" value="ALN56929"/>
        <property type="gene ID" value="GLE_1572"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1572"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1552"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="42" mass="4507" checksum="5AF38A6FB152A480" modified="2016-02-17" version="1">MRRPLSWHELPAVVGGASVPTLLCPIAVPLQAFGDLSEQHRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEU7</accession>
    <name>A0A0S2DEU7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">RNA polymerase sigma factor, sigma-70 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLE_1738</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1738"/>
    <dbReference type="EnsemblBacteria" id="ALN57093">
        <property type="protein sequence ID" value="ALN57093"/>
        <property type="gene ID" value="GLE_1738"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1738"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1715"/>
    <dbReference type="OMA" id="VKSRMRY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="7">
        <location>
            <begin position="57"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4" evidence="8">
        <location>
            <begin position="161"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="124"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN57093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="214" mass="24680" checksum="34932BDE553C4DE8" modified="2016-02-17" version="1">MILALQLPLYDPAAASKRFPSAPSARNLPPMNTAADTSDDVLMLAWAAGDAGAFEVLYSRHRGPLYRFLLRQLRDSALADEFFQDVWQRVIGARQGWKPDAQFNTWLFRIAHNRLNDYWRGLKHRPATPEDGDERAARVPDPTTPERELSEFEQRRRLQRAIEELPEEQREVVLLRLEQELSLEEIGAITGVGRETVKSRLRYAMDKLRARLTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF50</accession>
    <name>A0A0S2DF50_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1793</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57146">
        <property type="protein sequence ID" value="ALN57146"/>
        <property type="gene ID" value="GLE_1793"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1793"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="40" mass="4288" checksum="73CB631ED815B46B" modified="2016-02-17" version="1">MMPPAGRRGQPGGAIARASPPLRERRRRAHSTHCAGLHCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF76</accession>
    <name>A0A0S2DF76_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1884</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57236">
        <property type="protein sequence ID" value="ALN57236"/>
        <property type="gene ID" value="GLE_1884"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1884"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="59" mass="6888" checksum="E09E156DC95B5A68" modified="2016-02-17" version="1">MRERVHRTVRRGLRRASRRTARCRRAKVRQSFQTVRRTAAEPVMPSPSGFARRRSGHSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF98</accession>
    <name>A0A0S2DF98_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ferrous iron transport protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">feoB</name>
        <name evidence="12" type="ORF">GLE_1956</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Probable transporter of a GTP-driven Fe(2+) uptake system.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1956"/>
    <dbReference type="EnsemblBacteria" id="ALN57307">
        <property type="protein sequence ID" value="ALN57307"/>
        <property type="gene ID" value="GLE_1956"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1956"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1921"/>
    <dbReference type="OMA" id="CITSFAM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015093">
        <property type="term" value="F:ferrous iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055072">
        <property type="term" value="P:iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01879">
        <property type="entry name" value="FeoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003373">
        <property type="entry name" value="Fe2_transport_prot-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011640">
        <property type="entry name" value="Fe2_transport_prot_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030389">
        <property type="entry name" value="G_FEOB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07664">
        <property type="entry name" value="FeoB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02421">
        <property type="entry name" value="FeoB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00437">
        <property type="entry name" value="feoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51711">
        <property type="entry name" value="G_FEOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="4 10" id="KW-0410">Iron transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="228"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="289"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="367"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="405"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="465"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="567"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="602"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="domain" description="FeoB-type G" evidence="11">
        <location>
            <begin position="18"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN57307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="630" mass="67597" checksum="AF364F9456A97FE0" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFC6</accession>
    <name>A0A0S2DFC6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
            <ecNumber evidence="4">1.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">fabG</name>
        <name evidence="6" type="ORF">BV903_07280</name>
        <name evidence="7" type="ORF">FE772_08770</name>
        <name evidence="5" type="ORF">GLE_1692</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 4">Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000013">
        <property type="protein sequence ID" value="OPD64681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946982.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1692"/>
    <dbReference type="EnsemblBacteria" id="ALN57048">
        <property type="protein sequence ID" value="ALN57048"/>
        <property type="gene ID" value="GLE_1692"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64681">
        <property type="protein sequence ID" value="OPD64681"/>
        <property type="gene ID" value="BV903_07280"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1692"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1670"/>
    <dbReference type="OMA" id="KMPERDY"/>
    <dbReference type="OrthoDB" id="1601931at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011284">
        <property type="entry name" value="3oxo_ACP_reduc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01830">
        <property type="entry name" value="3oxo_ACP_reduc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="3 4" id="KW-0521">NADP</keyword>
    <keyword evidence="4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="15"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="63"/>
            <end position="64"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="155"/>
            <end position="159"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR611284-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR611284-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD64681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW25746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="248" mass="25411" checksum="FBD8576D5F965B93" modified="2016-02-17" version="1">MSTTPLSGEIALVTGASRGIGAAIADELAAQGATVIGTATSESGAAAIGERLAAHGGHGRVLNVADPASVESLLDAVAKEIGAISILVNNAGITRDNLLMRMKDEDWQAILDTNLSSVYRTSKAVMRSMMKARKGRIINIASVVGVTGNPGQANYAAAKAGVIAFSKSLAREIGSRGVTVNVVAPGFIDTDMTRDLPQDAKTAMFDQIALGRFGEPADIARAVAFLAGPGAGYITGETLHVNGGMYMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFT0</accession>
    <name>A0A0S2DFT0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DnaJ domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_1964</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947174.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1964"/>
    <dbReference type="EnsemblBacteria" id="ALN57315">
        <property type="protein sequence ID" value="ALN57315"/>
        <property type="gene ID" value="GLE_1964"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1964"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1929"/>
    <dbReference type="OMA" id="WQEESSA"/>
    <dbReference type="OrthoDB" id="1959687at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="325"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="354"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="392"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="425"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="451"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="492"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="61"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="83"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="510" mass="55925" checksum="3045749FAA887251" modified="2016-02-17" version="1">MTPFHRLGLAPDSDERAIKRAYARELKRCRPDDDPDGFQALNEAYQQCLRIAAQRAFALAAAQDAEGGSDDAQTETAAREMPGPVAPAPPSPPAAPTRAPAPAGEAAPPRPRPAPGSRPAARDEPQHAAEPQPRYFDLQAFLGELFDFAQRRLTVDLQRWLRDCEPLYSLQLKHALRAPVAHALAECEPPLAPAATDVIAEYFDLGALYDPDPRLRHWLAVASDRGARSVAFERILGEYRNAHDRLVDRWLFNELQRPALWPRRALIALIPTLPSRLRGLLLRLQRVGPEWLEQRLNPGAVGFWLRACDPERLDPRRIAIAAARIPLYYLAAIWFLSMLMGFDPAPRDNATRNIGLVFAGWAAAALAWIGLRRMQRWMVQRMRWDPLSAYTLALLAACAACAYWLPFQAALIAGIVGFVQARSRATPVPAMVCLLVAALAAVAITPPAARAYDATAPLVVVAAAAVLPLHDLALARRFGVTLAEVRAGAGKLWRLAQILAAVAVAGYLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG56</accession>
    <name>A0A0S2DG56_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2007</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57357">
        <property type="protein sequence ID" value="ALN57357"/>
        <property type="gene ID" value="GLE_2007"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2007"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="57" mass="6646" checksum="3F1256D0BDC9148B" modified="2016-02-17" version="1">MASERRARRPMRSPARLFFGRLAWWRLRRGCGGAXXXXXXXKRRAAKLARWFTSACS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG60</accession>
    <name>A0A0S2DG60_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Polysaccharide biosynthesis tyrosine autokinase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="13">Tyrosine-protein kinase</fullName>
            <ecNumber evidence="13 15">2.7.10.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">epsB</name>
        <name evidence="14" type="ORF">BV903_20235</name>
        <name evidence="15" type="ORF">FE772_11380</name>
        <name evidence="13" type="ORF">GLE_2258</name>
    </gene>
    <organism evidence="13 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">C3</strain>
        </source>
    </reference>
    <reference evidence="14 17" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">B25</strain>
        </source>
    </reference>
    <reference evidence="15 18" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 18">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.10.2" evidence="13 15"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000061">
        <property type="protein sequence ID" value="OPD62096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947405.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000061.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2258"/>
    <dbReference type="EnsemblBacteria" id="ALN57607">
        <property type="protein sequence ID" value="ALN57607"/>
        <property type="gene ID" value="GLE_2258"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62096">
        <property type="protein sequence ID" value="OPD62096"/>
        <property type="gene ID" value="BV903_20235"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2258"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2223"/>
    <dbReference type="OMA" id="QQIYIQL"/>
    <dbReference type="OrthoDB" id="1184929at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004715">
        <property type="term" value="F:non-membrane spanning protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045226">
        <property type="term" value="P:extracellular polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005702">
        <property type="entry name" value="EPS_synthesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032807">
        <property type="entry name" value="GNVR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003856">
        <property type="entry name" value="LPS_length_determ_N_term"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13807">
        <property type="entry name" value="GNVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02706">
        <property type="entry name" value="Wzz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01007">
        <property type="entry name" value="eps_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="447"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Wzz" evidence="11">
        <location>
            <begin position="17"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="GNVR" evidence="12">
        <location>
            <begin position="388"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="CbiA" evidence="10">
        <location>
            <begin position="553"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="276"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN57607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OPD62096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW26185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="740" mass="79446" checksum="0F85043FD777FCBA" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG89</accession>
    <name>A0A0S2DG89_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2288</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947424.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2288"/>
    <dbReference type="EnsemblBacteria" id="ALN57637">
        <property type="protein sequence ID" value="ALN57637"/>
        <property type="gene ID" value="GLE_2288"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2288"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2253"/>
    <dbReference type="OrthoDB" id="1297607at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043746">
        <property type="entry name" value="DUF5691"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18944">
        <property type="entry name" value="DUF5691"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="522" mass="56413" checksum="0BF031F04583B96E" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGA7</accession>
    <name>A0A0S2DGA7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH-quinone oxidoreductase subunit N</fullName>
            <ecNumber evidence="5">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">NADH dehydrogenase I subunit N</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">NDH-1 subunit N</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 10" type="primary">nuoN</name>
        <name evidence="9" type="ORF">BV903_08670</name>
        <name evidence="10" type="ORF">FE772_10960</name>
        <name evidence="8" type="ORF">GLE_2172</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the complex I subunit 2 family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000018">
        <property type="protein sequence ID" value="OPD64365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947336.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2172"/>
    <dbReference type="EnsemblBacteria" id="ALN57522">
        <property type="protein sequence ID" value="ALN57522"/>
        <property type="gene ID" value="GLE_2172"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64365">
        <property type="protein sequence ID" value="OPD64365"/>
        <property type="gene ID" value="BV903_08670"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2172"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2135"/>
    <dbReference type="OMA" id="FYIRVIV"/>
    <dbReference type="OrthoDB" id="1664448at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00445">
        <property type="entry name" value="NDH1_NuoN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010096">
        <property type="entry name" value="NADH-Q_OxRdtase_suN/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
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    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
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    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0874">Quinone</keyword>
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    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="162"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="205"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="328"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="371"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="408"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="450"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="7">
        <location>
            <begin position="127"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN57522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD64365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW26114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="481" mass="51179" checksum="DFA6A2E6E2E4A17E" modified="2016-02-17" version="1">MNMPVRSLADIMPLLPELVVVVGAFALLMLDLFVEERNRIVSHVFSILVVAAATAMIAFDVGGQGTVLSGMFVRDTAADVLKLGIGVVGILSLIYTWPYLRARGLYKGEVGVLMLFAIAGMMFLVSAGSLTMVYVGLEMLALCSYALVAVDRDSPLASEAAIKYFVLGALASGLLLYGLSLIYGATGSLMLDQIAVAASVGPKSMLLITGVVFVVAGIAFKFGAAPFHMWLPDVYQGAPTPITLFIGAAPKLAAFGMTYRLLEVGAHGLDHHWRLLLAGLAVLSLAIGNLSALLQTNLKRLLAYSTVSHVGFLFIGMAGGGAQGFAAAMFYAISYAIMTSAAFAAIIVMSSRGFEADRIDDYKGLNARNPWLAGMILCVMASLAGLPPFLGFWAKLAVLKAALQGDMLWLAIVGVVFAVIGAFYYLRVIKAMYFDEPEGKLPPPNEDRPLRVVFGVNALALLALGIAWNPIMEWCQRAFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGK8</accession>
    <name>A0A0S2DGK8_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Benzoate transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Benzoate/H(+) symporter BenE family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">benE</name>
        <name evidence="3" type="ORF">FE772_11970</name>
        <name evidence="2" type="ORF">GLE_2391</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947505.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57740">
        <property type="protein sequence ID" value="ALN57740"/>
        <property type="gene ID" value="GLE_2391"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2391"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2353"/>
    <dbReference type="OMA" id="MTSQNMP"/>
    <dbReference type="OrthoDB" id="1456447at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042925">
        <property type="term" value="F:benzoate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004711">
        <property type="entry name" value="Benzoate_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30199">
        <property type="entry name" value="PTHR30199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03594">
        <property type="entry name" value="BenE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00843">
        <property type="entry name" value="benE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
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        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
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        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="162"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="278"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="362"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="397" mass="40758" checksum="C23B2FA5ACA3C541" modified="2016-02-17" version="1">MPHLRDLSLSAVVAGFVAVLVGFTSSAAIVFSAAQASGADEAEIASWMWALELGMGITCIGLSLRYKVPVVTAWSTPGAAMLITGAAGLPLAEAIGAFVISAALTVALGFSGWLERVLARLPASLAAGMLAGVLLRFGLNVFTSMQHSFALVFAMFLGFLLARRWLPRYAVLVALAVGIAVAALQGGLHLDKLQLAVAMPVWTTPRFSLAATVGVAIPLFVVTMASQNVPGIAILRAHGYRDTPASPLIGWTGAANLLLAPFGAFALCLAAITAAICMGEDAHEDPRKRYLASVAAGVFYLLTGVFGATVAAAFAAFPQALVMAIAGIALLATIGNGLAAALGDPQERDPALITFLVTASGFTAFQIGSVFWGMVAGVLATVVLRLRKPAAAADPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGQ3</accession>
    <name>A0A0S2DGQ3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rhodanese domain protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Sulfurtransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_10570</name>
        <name evidence="2" type="ORF">GLE_2089</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947270.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2089"/>
    <dbReference type="EnsemblBacteria" id="ALN57439">
        <property type="protein sequence ID" value="ALN57439"/>
        <property type="gene ID" value="GLE_2089"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2089"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2054"/>
    <dbReference type="OMA" id="CDTHTNC"/>
    <dbReference type="OrthoDB" id="684577at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020936">
        <property type="entry name" value="TrhO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040503">
        <property type="entry name" value="TRHO_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43268">
        <property type="entry name" value="PTHR43268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17773">
        <property type="entry name" value="UPF0176_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="131"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="250" mass="27939" checksum="9C67F6FB3BCCFBF2" modified="2016-02-17" version="1">MVVNIAAYHFAVIDDPPQLAQRLREQAERLQLRGTALVAPEGINLFLAGDGEAIESLLADLRADPRFDPRFDTLAAKYSRSRAQPFARLKVKLKREIIAFRRERCSPLRGRAPSVTPDTLARWLDQGHDDAGKRVVLLDTRNREEVGYGSFDNALTLPIDNFTELPEALAPHREALREATVVSFCTGGIRCEKAALWLREDGMDNLLQLDGGILGYFERVGGRHYDGGCFVFDERVALDPQLRPLRDAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH08</accession>
    <name>A0A0S2DH08_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2383</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57732">
        <property type="protein sequence ID" value="ALN57732"/>
        <property type="gene ID" value="GLE_2383"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2383"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="755"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="782"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="828"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="883"/>
            <end position="897"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1077" mass="112829" checksum="0FA0172CB3926536" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH39</accession>
    <name>A0A0S2DH39_LYSEN</name>
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        <submittedName>
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        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">FE772_12065</name>
        <name evidence="2" type="ORF">GLE_2411</name>
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    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_2411"/>
    <dbReference type="EnsemblBacteria" id="ALN57760">
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        <property type="gene ID" value="GLE_2411"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2411"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2373"/>
    <dbReference type="OMA" id="HPFDRTM"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0016787">
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="43"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="232" mass="25274" checksum="E0F23EB7D516BFC4" modified="2016-02-17" version="1">MSDKQALLLLPGLLCDERLWREQIRDLADIADIGVPDLTQDDSVAGMAARVLAQAPPRFALAGLSMGGYVAFEILRQQPQRVRKLALFDTSAAPDSPLRAMQRRAGLRLLDRGRFAGVTQQLLPSLVHAEHVDGPVGAEVRAMAQRVGAQAYRRQQLAILERPDSRPLLASIAVPTLIAVGEDDRLTPPAAAEEIHRGIAGSVLERIAQCGHLPTMERPQVATALLRRWLQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH53</accession>
    <name>A0A0S2DH53_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_02405</name>
        <name evidence="4" type="ORF">FE772_12135</name>
        <name evidence="2" type="ORF">GLE_2427</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000004">
        <property type="protein sequence ID" value="OPD65630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947531.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57776">
        <property type="protein sequence ID" value="ALN57776"/>
        <property type="gene ID" value="GLE_2427"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65630">
        <property type="protein sequence ID" value="OPD65630"/>
        <property type="gene ID" value="BV903_02405"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2427"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2389"/>
    <dbReference type="OrthoDB" id="2056543at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046256">
        <property type="entry name" value="DUF6289"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19806">
        <property type="entry name" value="DUF6289"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595122" evidence="1">
        <location>
            <begin position="22"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD65630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="70" mass="7223" checksum="433E75B67F63E869" modified="2016-02-17" version="1">MQRFKLIVLGALLAASAGTGAATQTQGCFCSTIYYDDAGNTVGVRQPEACGDPGYGPTTKKYKVVAGCVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHR0</accession>
    <name>A0A0S2DHR0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cell envelope biogenesis protein OmpA</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Outer membrane protein, OmpA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_13210</name>
        <name evidence="5" type="ORF">GLE_2634</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW26479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2634"/>
    <dbReference type="EnsemblBacteria" id="ALN57982">
        <property type="protein sequence ID" value="ALN57982"/>
        <property type="gene ID" value="GLE_2634"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2634"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2593"/>
    <dbReference type="OMA" id="IGNYMDK"/>
    <dbReference type="OrthoDB" id="2018797at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027367">
        <property type="entry name" value="Gly-zipper_YMGG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13441">
        <property type="entry name" value="Gly-zipper_YMGG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpA-like" evidence="4">
        <location>
            <begin position="122"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW26479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="240" mass="25099" checksum="CF14762D316F0681" modified="2016-02-17" version="1">MKTPFKLAIAAATVTALLAGCATGGGGYYGGQQQPYPGDPNQPQQQQGGMSKTQKGALIGALAGVAAGLLSGNDATERRQRALIGAGVGGLAGGAIGNYQDRQERALRERMQGTGVDVIRQGDNITLNMPSNITFAFNSANLDPKFDPVLDNVASTLNEYNQTIVEVAGHTDSIGGDAVNQRLSEQRAASVGNYLMSKGLVRDRFILTGAGKTRPIASNDTEAGRAQNRRVEITLVPVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHY3</accession>
    <name>A0A0S2DHY3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF2939 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_18835</name>
        <name evidence="3" type="ORF">FE772_13445</name>
        <name evidence="1" type="ORF">GLE_2684</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000052">
        <property type="protein sequence ID" value="OPD62411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947734.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000052.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2684"/>
    <dbReference type="EnsemblBacteria" id="ALN58032">
        <property type="protein sequence ID" value="ALN58032"/>
        <property type="gene ID" value="GLE_2684"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62411">
        <property type="protein sequence ID" value="OPD62411"/>
        <property type="gene ID" value="BV903_18835"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2684"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2643"/>
    <dbReference type="OMA" id="YLWASPY"/>
    <dbReference type="OrthoDB" id="1692347at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021330">
        <property type="entry name" value="DUF2939"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11159">
        <property type="entry name" value="DUF2939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD62411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="183" mass="19289" checksum="5FEE14CDAFF730F0" modified="2016-02-17" version="1">MKKWIAALVVAAALLLGWVAAGPFMTVNAIRTAVKQGDTAALSKHVDFASVRLGLKAQVDDYLVRRAGPSVQSSLLGAIGLGMASSVAGGAVDAIATPMGIGAVLEGRNLLKRLDPSAPPRDAYAPVEPAEPLKQLSYRFETPSRFTATVANADGDPVVFVLTRQGLSWRVTEVRLPLDKMLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI60</accession>
    <name>A0A0S2DI60_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-hydroxyacyl-CoA dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">fadB</name>
        <name evidence="14" type="ORF">FE772_14535</name>
        <name evidence="13" type="ORF">GLE_2913</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">C3</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:22432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57318"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="1.1.1.35"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.35" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947904.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2913"/>
    <dbReference type="EnsemblBacteria" id="ALN58261">
        <property type="protein sequence ID" value="ALN58261"/>
        <property type="gene ID" value="GLE_2913"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2913"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2875"/>
    <dbReference type="OMA" id="GQGFYKK"/>
    <dbReference type="OrthoDB" id="82358at2"/>
    <dbReference type="UniPathway" id="UPA00659"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003857">
        <property type="term" value="F:3-hydroxyacyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3HCDH_N" evidence="12">
        <location>
            <begin position="10"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="11">
        <location>
            <begin position="195"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN58261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW26687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="791" mass="85325" checksum="13587B565DAC15EA" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIC0</accession>
    <name>A0A0S2DIC0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_2934</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2934"/>
    <dbReference type="EnsemblBacteria" id="ALN58282">
        <property type="protein sequence ID" value="ALN58282"/>
        <property type="gene ID" value="GLE_2934"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2934"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2896"/>
    <dbReference type="OMA" id="LLMHGWE"/>
    <dbReference type="OrthoDB" id="721431at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013595">
        <property type="entry name" value="Pept_S33_TAP-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08386">
        <property type="entry name" value="Abhydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="3">
        <location>
            <begin position="86"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Abhydrolase_4" evidence="2">
        <location>
            <begin position="219"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="308" mass="33567" checksum="C6BF236EBDF8E7EA" modified="2016-02-17" version="1">MRTAITKISTTVRHVAQLYGLRLGFAVGGWLAPEATMRRAAELFCTPFASTRRRALAAPTFDAREDVLRVDGRAIACYVWGEPQRQPYVLFAHGWSSHGTRVARWLPALRAAGYAVVAFDQPAHGRSEGRLATLPDFTRHLQAVGAHYGPAAAVIGHSLGGAATLLAMARGLRAERAVLIAPAADPVAAVKRFARFLWVGEDLCRRMFAYFEARIGISFDSQQAHRNAPSMGRPALIVHDLGDREVPWAEGERYARYWPGARLLTTQGLGHNRIADDTAVIGAALRFLRGEAVGDKVVSSENLPYGMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIF5</accession>
    <name>A0A0S2DIF5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cysteine dioxygenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Cysteine dioxygenase type I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BV903_06330</name>
        <name evidence="4" type="ORF">GLE_2837</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">B25</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cysteine dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000011">
        <property type="protein sequence ID" value="OPD64816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2837"/>
    <dbReference type="EnsemblBacteria" id="ALN58185">
        <property type="protein sequence ID" value="ALN58185"/>
        <property type="gene ID" value="GLE_2837"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64816">
        <property type="protein sequence ID" value="OPD64816"/>
        <property type="gene ID" value="BV903_06330"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2837"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2795"/>
    <dbReference type="OMA" id="WCVEGVW"/>
    <dbReference type="OrthoDB" id="1571420at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010300">
        <property type="entry name" value="CDO_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12918">
        <property type="entry name" value="PTHR12918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05995">
        <property type="entry name" value="CDO_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0883">Thioether bond</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="cross-link" description="3'-(S-cysteinyl)-tyrosine (Cys-Tyr)" evidence="2">
        <location>
            <begin position="101"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR610300-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR610300-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD64816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="198" mass="21916" checksum="93504E750DCE6D34" modified="2016-02-17" version="1">MNATDALPDFDFPGHDKLVAAIDAAVAAGDEHAVTAALRNTLCKMIRDRDVNLPDCVFDPIEDHYARRELYRSPELGYSVVAMTWGPGQGTPMHDHSGLWCVEGVWDGELEITQYELLERNGENFRFRAAGGMHAGPGSAGSLIPPHEYHTIRNASEDAVAVSLHIYKAPMECCSMFVPREGEWFRRVDKALETDEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIQ5</accession>
    <name>A0A0S2DIQ5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RDD family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">RDD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BV903_25055</name>
        <name evidence="9" type="ORF">FE772_15690</name>
        <name evidence="7" type="ORF">GLE_3155</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000104">
        <property type="protein sequence ID" value="OPD61167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948084.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000104.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3155"/>
    <dbReference type="EnsemblBacteria" id="ALN58501">
        <property type="protein sequence ID" value="ALN58501"/>
        <property type="gene ID" value="GLE_3155"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61167">
        <property type="protein sequence ID" value="OPD61167"/>
        <property type="gene ID" value="BV903_25055"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3155"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3112"/>
    <dbReference type="OMA" id="RCLHDHL"/>
    <dbReference type="OrthoDB" id="1974702at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010432">
        <property type="entry name" value="RDD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06271">
        <property type="entry name" value="RDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="31"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="RDD" evidence="6">
        <location>
            <begin position="25"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD61167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW26871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="170" mass="18605" checksum="B3E2F37112FD6ABA" modified="2016-02-17" version="1">MDPQNPYQSPQSPLIAPNGGEQELADRGIRLVAAIIDGVILMVLLVPLMFIGGYMDAVMQAAQTGQQPYGLQIAWGVGALLLFFAVQYLPLSQNGQTWGKKVMKIKIVDQDGNKPDLVTLMGKRYLFQNGIGLIPCLGGLISLVDVLMIFRQDRRCLHDQIAGTRVVVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIZ6</accession>
    <name>A0A0S2DIZ6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">4-hydroxy-3-methylbut-2-enyl diphosphate reductase</fullName>
            <shortName evidence="5">HMBPP reductase</shortName>
            <ecNumber evidence="5">1.17.7.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">ispH</name>
        <name evidence="7" type="synonym">lytB</name>
        <name evidence="7" type="ORF">FE772_16260</name>
        <name evidence="6" type="ORF">GLE_3284</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:24488"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="EC" id="1.17.7.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:24825"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="EC" id="1.17.7.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from (2E)-4-hydroxy-3-methylbutenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the IspH family.</text>
    </comment>
    <dbReference type="EC" id="1.17.7.4" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948178.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3284"/>
    <dbReference type="EnsemblBacteria" id="ALN58630">
        <property type="protein sequence ID" value="ALN58630"/>
        <property type="gene ID" value="GLE_3284"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3284"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3236"/>
    <dbReference type="OMA" id="HNKYVVD"/>
    <dbReference type="OrthoDB" id="1311145at2"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00097"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00059">
        <property type="reaction ID" value="UER00105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051745">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050992">
        <property type="term" value="P:dimethylallyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13944">
        <property type="entry name" value="lytB_ispH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00191">
        <property type="entry name" value="IspH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003451">
        <property type="entry name" value="LytB/IspH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30426">
        <property type="entry name" value="PTHR30426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02401">
        <property type="entry name" value="LYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00216">
        <property type="entry name" value="ispH_lytB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="227"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW26956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="316" mass="34650" checksum="9B1186790E5D0F82" modified="2016-02-17" version="1">MDVLLANPRGFCAGVDRAIEIVKRAIETLGAPIYVRHEVVHNRFVVDDLKHRGAVFVEELDEVPDGATVIFSAHGVSKAVRAEAERRGLKVFDATCPLVTKVHLEVSRHCRAGRDVVLIGHEGHPEVEGTMGQWKREAGSGRIYLVEDADDVAAMQVDQPDNLAYTTQTTLSVDDTRSVIEALRAKYPAIQGPKNDDICYATQNRQDSVRELAARCDLVLVVGSPNSSNSNRLRELAEREGVTSYLIDGADEIDPRWVEGRSRIGITAGASAPEVLVRGVIDRLSELGAQHVTELDGEQESMVFALPKELRLQLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ19</accession>
    <name>A0A0S2DJ19_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3054</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3054"/>
    <dbReference type="EnsemblBacteria" id="ALN58401">
        <property type="protein sequence ID" value="ALN58401"/>
        <property type="gene ID" value="GLE_3054"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3054"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3014"/>
    <dbReference type="OMA" id="DWAFDHL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="13"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="187" mass="20774" checksum="CEB1C9E0C6E255D5" modified="2016-02-17" version="1">MMTIADIELETPRLLLRPPRLEDFDAWAQFMGAGDYLRYIGGPQPRPVAWRGLMSVIGSWAALGYGFFSVFEKSSGRWIGRLGPWQPDGWPGTEVGWGIVESAGGQGYASEGAAASIDWAFDHLGWSEVIHTIDAGNLASKGVARKLGSRYLRQDRLPEPFHEKEVEVWGQSREEWRARRKAGAAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJC9</accession>
    <name>A0A0S2DJC9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3395</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3395"/>
    <dbReference type="EnsemblBacteria" id="ALN58741">
        <property type="protein sequence ID" value="ALN58741"/>
        <property type="gene ID" value="GLE_3395"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3395"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3344"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="102" mass="11109" checksum="853758B4C7BD5691" modified="2016-02-17" version="1">MNDPIDPVSTSPSTAAAPRRGSSAWLWLLLALLVAAGGGWFGWREWQQREVRERXXXXXXXXPAKPTDATSPTARGHRRGRRCPVAACAAPTRQARSLAICL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJT2</accession>
    <name>A0A0S2DJT2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase, UbiE/COQ5 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3509</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948342.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58854">
        <property type="protein sequence ID" value="ALN58854"/>
        <property type="gene ID" value="GLE_3509"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3509"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3453"/>
    <dbReference type="OMA" id="GVMFFED"/>
    <dbReference type="OrthoDB" id="1664438at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="56"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="291" mass="31264" checksum="306598F20E807DB4" modified="2016-02-17" version="1">METPIPDAPPNAEQIEYWNGAVGLRWLTYNDWLDERTAAYGRAAFAAAAPRPGEAVLDIGCGAGATTFELARAVGRDGSATGIDISAPLLGRARERAAALGLAVEFLEADASRPPFAPQRFDLLFSRFGVMFFDDPVAAFAELRKTLKPGGRIAFACWQEPQLNDWYELPLAAIAHLVERAPVDTRQPGPFAFSDPGYTREVLTAAGFAQIELAPFATPFYLGRGATREAMADDAMEQVFRVGPVARLLEGRGEELNAAARDAIRVALLQLADDDGLEVGGAIWVVTARAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK22</accession>
    <name>A0A0S2DK22_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF4442 domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Tetrameric acyl-CoA thioesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_18070</name>
        <name evidence="4" type="ORF">FE772_16985</name>
        <name evidence="2" type="ORF">GLE_3448</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000048">
        <property type="protein sequence ID" value="OPD62567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948301.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000048.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3448"/>
    <dbReference type="EnsemblBacteria" id="ALN58793">
        <property type="protein sequence ID" value="ALN58793"/>
        <property type="gene ID" value="GLE_3448"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62567">
        <property type="protein sequence ID" value="OPD62567"/>
        <property type="gene ID" value="BV903_18070"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3448"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3396"/>
    <dbReference type="OMA" id="HLRWFEN"/>
    <dbReference type="OrthoDB" id="1814691at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027961">
        <property type="entry name" value="DUF4442"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14539">
        <property type="entry name" value="DUF4442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="149" mass="17040" checksum="1D497A6F7EFBB0F4" modified="2016-02-17" version="1">MKASTLRFGLNLWPPFLFTGVHVAAISPDYRHAAVELRMRPWNRNYVGTHFGGSLFAMTDPFWMLLAMNALGRDYIVWDRAGGIEFLKPGRGTVTARFDLSDEILDELRAATAGGDKYLRWFDNDIVDASGETVAKVRKQLYVRRKRDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK34</accession>
    <name>A0A0S2DK34_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Response regulator transcription factor</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_17475</name>
        <name evidence="5" type="ORF">GLE_3550</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948374.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3550"/>
    <dbReference type="EnsemblBacteria" id="ALN58894">
        <property type="protein sequence ID" value="ALN58894"/>
        <property type="gene ID" value="GLE_3550"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3550"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3494"/>
    <dbReference type="OMA" id="LDRFAPM"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RESPONSE_REGULATORY"/>
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    </dbReference>
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    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="7"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="147"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW27158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="215" mass="23490" checksum="89E68406A3C75AB8" modified="2016-02-17" version="1">MSEPNVRVLIADDHTMVRESLAGLLRGAGIDVVAQAADGVQTLQRAQELQPDVVVTDLSMPGLNGLEVVRRLRELAPAPRVLVLTMHQEDEYILQAVRAGAAGYVVKDSPATELLTAVREVHAGRGYFGPQAARALAEQLRHPGRDLGDPYGRLTAREREVFHLIADALTTKEIARRLAISVKTAENHRARVLDKLGVRNSAELVRYASRKGLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK62</accession>
    <name>A0A0S2DK62_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Type II secretion system protein H</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">General secretion pathway protein H</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BV903_16810</name>
        <name evidence="13" type="ORF">GLE_3580</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">C3</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">B25</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000045">
        <property type="protein sequence ID" value="OPD62757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3580"/>
    <dbReference type="EnsemblBacteria" id="ALN58924">
        <property type="protein sequence ID" value="ALN58924"/>
        <property type="gene ID" value="GLE_3580"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62757">
        <property type="protein sequence ID" value="OPD62757"/>
        <property type="gene ID" value="BV903_16810"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3580"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3524"/>
    <dbReference type="OMA" id="NGDWANG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022346">
        <property type="entry name" value="T2SS_GspH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12019">
        <property type="entry name" value="GspH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="GspH" evidence="12">
        <location>
            <begin position="44"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN58924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OPD62757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="176" mass="18782" checksum="7E476297831CF637" modified="2016-02-17" version="1">MSRRRTAGFTLIELLVTIAIGAVLIGLALPSFTDALRSSRVTSAANEFSASVALARSEAIRSGRTGYMCASVNGTSCGGQWNDGWLVWTDLNNNAVADADERPRRTESVRDVDLTATASAGGSTTALKFDNRGRLSEGGKRDFVLKAVSCRSGANQLRKFELSTTGQVTMEKDKCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKA7</accession>
    <name>A0A0S2DKA7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transporter, major facilitator superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_3739</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3739"/>
    <dbReference type="EnsemblBacteria" id="ALN59083">
        <property type="protein sequence ID" value="ALN59083"/>
        <property type="gene ID" value="GLE_3739"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3739"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3684"/>
    <dbReference type="OMA" id="GIGFPYS"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="161"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="290"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="317"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="346"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="374"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="412"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="24"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="442" mass="48479" checksum="9C05B655F1B156A5" modified="2016-02-17" version="1">MSAITTTDAPAAASGMTPGQRLKSIFSGSVGNLVEYYDWYVYSAFSLYFAHVFFPSGDRISQALNAGAIFAVGFLMRPLGGWVFGRYADRHGRRAALMLSVLLMCAGSLIITFTPGYGTIGVFAPILLVAARLMQGLSVGGEYGSSATYLSEMSSRENRGFWSSFLYVTLILGQLLALLVLIVLQQFVLSEEQLRSWGWRIPFGIGAIAAITALYLRRNMQETESFTKLKNSDAPARREGSLRTLMRHPRAVLTVVGLTMGGTLAFYTYTNYMLKFLTISTGFDKETASLINAATLFVYMLMQPLVGALSDRIGRRPILIAFGVLGTILTVPVMHWIRGAQTPMEAFWLIMILLSAVSGYTAINAVVKAELFPVEVRALGVGLPYALTVALFGGTAEPVALWFKKIGMETGFFWYVSACIFCSLLVYALMPDTRKHSTIDRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKE8</accession>
    <name>A0A0S2DKE8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_18460</name>
        <name evidence="2" type="ORF">GLE_3750</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59094">
        <property type="protein sequence ID" value="ALN59094"/>
        <property type="gene ID" value="GLE_3750"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3750"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3694"/>
    <dbReference type="OMA" id="CAANTLQ"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242243" evidence="1">
        <location>
            <begin position="22"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="192" mass="21316" checksum="A2DC93225B479323" modified="2016-02-17" version="1">MTLRLKTFAAALAVLALAGCAANTLQRAGASTVFDLRLDSTLDWARIKGARQETWTIDGTRLNQLRIYSNIKPGEHVFMARKEKASKPDGPWFRSGMRPDELRDLVLDGLREEGAVNLDSGELHPHRFGAVDGLRFDFAMSNADGLNYKGTVAAVEREGKLTSLVWMAPSEHYYSRDAAAVGRMLDTMQFVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKI3</accession>
    <name>A0A0S2DKI3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent outer membrane receptor</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="10">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FE772_18025</name>
        <name evidence="9" type="ORF">GLE_3666</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948455.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3666"/>
    <dbReference type="EnsemblBacteria" id="ALN59010">
        <property type="protein sequence ID" value="ALN59010"/>
        <property type="gene ID" value="GLE_3666"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3666"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3610"/>
    <dbReference type="OMA" id="YTEAYGQ"/>
    <dbReference type="OrthoDB" id="173242at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010104">
        <property type="entry name" value="TonB_rcpt_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01782">
        <property type="entry name" value="TonB-Xanth-Caul"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726732" evidence="6">
        <location>
            <begin position="28"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="81"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="7">
        <location>
            <begin position="497"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="278"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN59010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="1031" mass="111501" checksum="49AF393CC3FD2023" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKK4</accession>
    <name>A0A0S2DKK4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sodium bile acid symporter family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3735</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948510.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3735"/>
    <dbReference type="EnsemblBacteria" id="ALN59079">
        <property type="protein sequence ID" value="ALN59079"/>
        <property type="gene ID" value="GLE_3735"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3735"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3680"/>
    <dbReference type="OMA" id="MEIGIHN"/>
    <dbReference type="OrthoDB" id="1493959at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004710">
        <property type="entry name" value="Bilac:Na_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10361">
        <property type="entry name" value="PTHR10361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="296" mass="30869" checksum="562A29930954852A" modified="2016-02-17" version="1">MQDSVLLKIGLPLAIAIIMCGIGLTLRGEDFRQILRRPRPVAVGLVGHYLLLPLLGFATAWWVARAGGPGAVEFAVGFVLVAACPSGSSSNALTYLARGNVALAVTLTVISALATFLSVPLLVDLALHWFGGETRGIRLPFAQTVLHLAALVLAPVLSGMALRRFAPAFALRVEPWVSRFALGLLLLLIVAICITQREVLTRSLGELGPAALAMGATAIGGGFLLGRIARLGLRDSITVGMEVGVQNSTLAIVIALTLLQSPAIAVPAAVYGLLMYLPAFAAAWLGRRAVARAEGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKL8</accession>
    <name>A0A0S2DKL8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="5">PPIase</shortName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BV903_22850</name>
        <name evidence="10" type="ORF">D9T17_09615</name>
        <name evidence="9" type="ORF">FE772_18465</name>
        <name evidence="7" type="ORF">GLE_3751</name>
    </gene>
    <organism evidence="7 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 11">C3</strain>
        </source>
    </reference>
    <reference evidence="8 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">OH11</strain>
        </source>
    </reference>
    <reference evidence="9 14" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000077">
        <property type="protein sequence ID" value="OPD61583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000023">
        <property type="protein sequence ID" value="ROU07217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948523.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3751"/>
    <dbReference type="EnsemblBacteria" id="ALN59095">
        <property type="protein sequence ID" value="ALN59095"/>
        <property type="gene ID" value="GLE_3751"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61583">
        <property type="protein sequence ID" value="OPD61583"/>
        <property type="gene ID" value="BV903_22850"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3751"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3695"/>
    <dbReference type="OMA" id="VPFHRVM"/>
    <dbReference type="OrthoDB" id="1861282at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PTHR45625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD61583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW27327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROU07217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="168" mass="18113" checksum="38CCE54FB1ED9707" modified="2016-02-17" version="1">MSLIATFDTSRGPIRVELNAEKAPLTVANFVNLAQRGFYDGLNFHRVIPNFMIQGGCPQGTGTGGPGYRFEDETRNGLGHQRGVLSMANAGPGTNGSQFFITHIVCDWLDGKHTVFGKVLEGQEIVDTVQQGDKLNSVKIEGDTAAVLAAKAERVAEWNKVLDANARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKN4</accession>
    <name>A0A0S2DKN4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3502</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58847">
        <property type="protein sequence ID" value="ALN58847"/>
        <property type="gene ID" value="GLE_3502"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3502"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="55" mass="5966" checksum="7FD5ECF6291BF8C5" modified="2016-02-17" version="1">MAENRLQGEHAGSLWAGRGEAVRRVRMGVGDRPGRRRAPPRRRAGTGRAGAIMTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKS2</accession>
    <name>A0A0S2DKS2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glucose 1-dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.47</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Short chain dehydrogenase/reductase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_18260</name>
        <name evidence="2" type="ORF">GLE_3705</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.47" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948488.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3705"/>
    <dbReference type="EnsemblBacteria" id="ALN59049">
        <property type="protein sequence ID" value="ALN59049"/>
        <property type="gene ID" value="GLE_3705"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3705"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3649"/>
    <dbReference type="OMA" id="WEVANVI"/>
    <dbReference type="OrthoDB" id="1135906at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047936">
        <property type="term" value="F:glucose 1-dehydrogenase [NAD(P)] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="287" mass="30579" checksum="419353C83F5C0AA7" modified="2016-02-17" version="1">MNEPVSRTPPPQAQDQQPGQQSEMVPPPLSIRESYRGSGRLRGKVALISGGDSGIGRAVAQHFAREGAKVAIAYLNEDEDAERTRELVIAEDSDCMLIRGDLGDPARCREAVAKTVGAFGRLDILVNNAGEQHEVDAPEQLTPEQVERTFRTNIFAYIHLATAALEHLPKGGSIINTGSVTGVRGHEKLIDYAATKGAIHAFTFSLAQAVADRGIRVNAVAPGPIWTPLIPASFSPDEVAKFGKSTLMKRPGQPAEVAPAYVYLASEEASFVTGQTIHINGGGHISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL25</accession>
    <name>A0A0S2DL25_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">Elongation factor G</fullName>
            <shortName evidence="8">EF-G</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 13" type="primary">fusA</name>
        <name evidence="12" type="ORF">BV903_21055</name>
        <name evidence="13" type="ORF">FE772_18665</name>
        <name evidence="11" type="ORF">GLE_3793</name>
    </gene>
    <organism evidence="11 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">C3</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">B25</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000067">
        <property type="protein sequence ID" value="OPD61930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948557.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000067.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3793"/>
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</entry>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
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</entry>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
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        </source>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="81" mass="9026" checksum="773F7B52AB41FC2E" modified="2016-02-17" version="1">MSLSIRRAKARAAALLDALEVGETWDVSDAERAFNFDRHWAVLVAQAPRGLRGHLLDLGRQARDTSPTFGRLLRSMGLPNR</sequence>
</entry>
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    <name>A0A0S2DLJ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
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        </lineage>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="44" mass="4636" checksum="D131A3698E63FCB3" modified="2016-02-17" version="1">MEAHWETLHGPVRCGQRRGGVPESCLDAACALASAVRRAMAALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLR3</accession>
    <name>A0A0S2DLR3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Prepilin-type N-terminal cleavage/methylation domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Type IV pilus assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pilA</name>
        <name evidence="6" type="ORF">FE772_20170</name>
        <name evidence="5" type="ORF">GLE_4114</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the N-Me-Phe pilin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948795.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4114"/>
    <dbReference type="EnsemblBacteria" id="ALN59456">
        <property type="protein sequence ID" value="ALN59456"/>
        <property type="gene ID" value="GLE_4114"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4114"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4056"/>
    <dbReference type="OMA" id="SEDPITW"/>
    <dbReference type="OrthoDB" id="1970253at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009289">
        <property type="term" value="C:pilus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001082">
        <property type="entry name" value="Pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00114">
        <property type="entry name" value="Pilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0281">Fimbrium</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0488">Methylation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW27609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="147" mass="15480" checksum="C170980682541694" modified="2016-02-17" version="1">MKKQQGFTLIELMIVIAILGILIAIALPAYQDYQVRTKATEGLNVAAAAKLAVAESANDNGGVTKVTKANTAYTFTANSTKYVAAVEVGNEGVINITTRATGATNDIKFTLTPDENDDRSAIAWTCTYTGGDKESQIPSSCRAKAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLS7</accession>
    <name>A0A0S2DLS7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase</fullName>
            <ecNumber evidence="2">2.5.1.145</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 3" type="primary">lgt</name>
        <name evidence="4" type="ORF">BV903_19140</name>
        <name evidence="5" type="ORF">FE772_19250</name>
        <name evidence="3" type="ORF">GLE_3921</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-cysteinyl-[prolipoprotein] = H(+) + S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[prolipoprotein] + sn-glycerol 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:56712"/>
            <dbReference type="Rhea" id="RHEA-COMP:14679"/>
            <dbReference type="Rhea" id="RHEA-COMP:14680"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57685"/>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
            <dbReference type="ChEBI" id="CHEBI:140658"/>
            <dbReference type="EC" id="2.5.1.145"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; lipoprotein biosynthesis (diacylglyceryl transfer).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Lgt family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.145" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000054">
        <property type="protein sequence ID" value="OPD62338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948648.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000054.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3921"/>
    <dbReference type="EnsemblBacteria" id="ALN59263">
        <property type="protein sequence ID" value="ALN59263"/>
        <property type="gene ID" value="GLE_3921"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62338">
        <property type="protein sequence ID" value="OPD62338"/>
        <property type="gene ID" value="BV903_19140"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3921"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3858"/>
    <dbReference type="OMA" id="TDVPWAI"/>
    <dbReference type="OrthoDB" id="435911at2"/>
    <dbReference type="UniPathway" id="UPA00664"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008961">
        <property type="term" value="F:phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042158">
        <property type="term" value="P:lipoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01147">
        <property type="entry name" value="Lgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001640">
        <property type="entry name" value="Lgt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30589">
        <property type="entry name" value="PTHR30589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01790">
        <property type="entry name" value="LGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00544">
        <property type="entry name" value="lgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01311">
        <property type="entry name" value="LGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="19"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="252"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)</name>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD62338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW27457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="297" mass="33366" checksum="0E4D6377B3CD5183" modified="2016-02-17" version="1">MIILHQIDPIAISLGPLQVHWYGIMYLLGFVTAWWLGRQRVRAGRLPGVGEQAYGDLLFYAMLGVVLGGRIGYVLFYGFADLMRDPLMLLRIWEGGMSFHGGLLGVVAAMWWWSRSHRTHFFDTADFIAPLVPPGLGFGRLGNYIGGELWGKFTDGGWGVVFPRAPEFANWSAQQLQTQFAAGALERYARHPSQLYQAALEGLTMFALLWWFSRKPRPRYAVSGLFALLYGAFRFLVEFVRVPDQQLGDHGYLAFGWLTMGQVLSVPLIVLGLFWLWLSTRSPTLQPQPPAAEPAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLU9</accession>
    <name>A0A0S2DLU9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">30S ribosomal protein S3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 13" type="primary">rpsC</name>
        <name evidence="14" type="ORF">BV903_23005</name>
        <name evidence="16" type="ORF">D9T17_09460</name>
        <name evidence="15" type="ORF">FE772_18620</name>
        <name evidence="13" type="ORF">GLE_3784</name>
    </gene>
    <organism evidence="13 17">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 17">C3</strain>
        </source>
    </reference>
    <reference evidence="14 18" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 18">B25</strain>
        </source>
    </reference>
    <reference evidence="16 19" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 19">OH11</strain>
        </source>
    </reference>
    <reference evidence="15 20" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 20">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 10">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000077">
        <property type="protein sequence ID" value="OPD61611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000023">
        <property type="protein sequence ID" value="ROU07187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948550.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3784"/>
    <dbReference type="EnsemblBacteria" id="ALN59128">
        <property type="protein sequence ID" value="ALN59128"/>
        <property type="gene ID" value="GLE_3784"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61611">
        <property type="protein sequence ID" value="OPD61611"/>
        <property type="gene ID" value="BV903_23005"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3784"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3728"/>
    <dbReference type="OMA" id="KTNPIGN"/>
    <dbReference type="OrthoDB" id="1132353at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01309_B">
        <property type="entry name" value="Ribosomal_S3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005704">
        <property type="entry name" value="Ribosomal_S3_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_S3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018280">
        <property type="entry name" value="Ribosomal_S3_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="SSF54821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01009">
        <property type="entry name" value="rpsC_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00548">
        <property type="entry name" value="RIBOSOMAL_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KH type-2" evidence="12">
        <location>
            <begin position="39"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="213"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="216"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN59128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OPD61611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW27355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROU07187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="253" mass="28624" checksum="25A192E3B9E20371" modified="2016-02-17" version="1">MGHKVHPTGIRLGIAKDWNSKWFANKKQYAEYLAADLKVREMLRKKLAQAGISKIFIERPANNARVTIHTARPGVVIGKRGEDIEKLRKEVSNLMGVPAHINVTEVRKPELDAQLVAESIAQQLERRIMFRRAMKRAVGNAMRLGALGIKVNVAGRLNGAEIARSEWYREGRVPLHTLRADIDYGFAEAKTTYGIIGIKTWIYKGEVFDFAQVGQEKQDDSPRNERGDRGDRGDRGDRGDRNDRSGRPAREQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM27</accession>
    <name>A0A0S2DM27_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase</fullName>
            <ecNumber evidence="10">2.4.1.227</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 13" type="primary">murG</name>
        <name evidence="13" type="ORF">GLE_4131</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-glucosamine = di-trans-octa-cis-undecaprenyl diphospho-[N-acetyl-alpha-D-glucosaminyl-(1-&gt;4)]-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + H(+) + UDP</text>
            <dbReference type="Rhea" id="RHEA:31227"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:61387"/>
            <dbReference type="ChEBI" id="CHEBI:61388"/>
            <dbReference type="EC" id="2.4.1.227"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the glycosyltransferase 28 family. MurG subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.227" evidence="10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4131"/>
    <dbReference type="EnsemblBacteria" id="ALN59473">
        <property type="protein sequence ID" value="ALN59473"/>
        <property type="gene ID" value="GLE_4131"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4131"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4073"/>
    <dbReference type="OMA" id="AADMMLC"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051991">
        <property type="term" value="F:UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050511">
        <property type="term" value="F:undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030259">
        <property type="term" value="P:lipid glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00033">
        <property type="entry name" value="MurG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006009">
        <property type="entry name" value="GlcNAc_MurG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01133">
        <property type="entry name" value="murG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="1 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 10" id="KW-0133">Cell shape</keyword>
    <keyword evidence="9 10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 10 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_28" evidence="11">
        <location>
            <begin position="2"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_tran_28_C" evidence="12">
        <location>
            <begin position="179"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-N-acetyl-alpha-D-glucosamine binding" evidence="10">
        <location>
            <begin position="8"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN59473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="352" mass="36420" checksum="24098BD779BB5BFA" modified="2016-02-17" version="1">MLILAGGTGGHIFPGLAVAKALRARGVAVAWLGADGGMETRLVPQHGIEIDTLAIGGVRGKGVATLLRAPFRLAASVRAAGRVLRQRQPRAVVSFGGYAAGPGGLAARLAGLPLIVHEQNRAPGLTNRVLSRFARRVLTGFPDTFGDHDDVVGNPVRAEIAAIAPPAQRFAERSGPLKLLVLGGSQGARALNRAVPEAVAGLRGRVPCEVRHQCGEKMLADAQEAYAKAGVAASLEPFIADMAAAYAWADLVVCRAGALTLAELCAAGVGSVLVPFPQAVDDHQTKNARYLVDRGAAQLLPQAGDDLGARLSATIEILAERGVLLQMAEAARAIAKPDAAERVADAVLEVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DME1</accession>
    <name>A0A0S2DME1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytosol aminopeptidase family, catalytic domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_4458</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M17 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949070.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4458"/>
    <dbReference type="EnsemblBacteria" id="ALN59799">
        <property type="protein sequence ID" value="ALN59799"/>
        <property type="gene ID" value="GLE_4458"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4458"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4395"/>
    <dbReference type="OMA" id="HFDIYGW"/>
    <dbReference type="OrthoDB" id="356206at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00433">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="PTHR11963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00631">
        <property type="entry name" value="CYTOSOL_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTOSOL_AP" evidence="6">
        <location>
            <begin position="305"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="458" mass="48639" checksum="3F7069A9892A3026" modified="2016-02-17" version="1">MSEPLGFTSSASGALPLDLVGRVDFAAWRDALPPASAAWVQTQGFDGAPGTVVLVPGPDGELLGAAIGIGDPLDPYSYGHAPFALPARSWRAPTGLGPGVRDALRLGWGLGSYRFDRYKAPPRAPAQLLAEGFDDEVFAVLAASVRVRDLVNTPTEHMGPDELEQIAREIAERHGARIEVIAGDELLARNFPAIHAVGRASHRAPRLIALDWGDAAHPHVAVVGKGVCFDTGGLDLKPADGMRWMKKDMGGAAHAIALAELIMARKLPLRITLLVPAVENAVGPNAFRPGEVIATRQGTSVEIDNTDAEGRVVLCDALAYAGERKPALLLDFATLTGAARIALGPDLPALYSNQDALAQDWLDAGTAQRDPVWRMPLWRPYLRYLTSHIADIANGGPSKMAGSVTAALYLERFVPADLAWAHLDVYSWNDADRPGRPAGGEAQGLRAVFAMLKARAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMI5</accession>
    <name>A0A0S2DMI5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Methyltransferase domain family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_20765</name>
        <name evidence="3" type="ORF">GLE_4240</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948896.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4240"/>
    <dbReference type="EnsemblBacteria" id="ALN59581">
        <property type="protein sequence ID" value="ALN59581"/>
        <property type="gene ID" value="GLE_4240"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4240"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4181"/>
    <dbReference type="OrthoDB" id="803708at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01444">
        <property type="entry name" value="fkbM_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_21" evidence="1">
        <location>
            <begin position="43"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransf_11" evidence="2">
        <location>
            <begin position="298"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="525" mass="57999" checksum="0182A9E935F38382" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMV2</accession>
    <name>A0A0S2DMV2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">MurR/RpiR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, RpiR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_14105</name>
        <name evidence="5" type="ORF">FE772_22450</name>
        <name evidence="3" type="ORF">GLE_4602</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000036">
        <property type="protein sequence ID" value="OPD63263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949173.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4602"/>
    <dbReference type="EnsemblBacteria" id="ALN59943">
        <property type="protein sequence ID" value="ALN59943"/>
        <property type="gene ID" value="GLE_4602"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63263">
        <property type="protein sequence ID" value="OPD63263"/>
        <property type="gene ID" value="BV903_14105"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4602"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4537"/>
    <dbReference type="OMA" id="QDLEHAP"/>
    <dbReference type="OrthoDB" id="992687at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05013">
        <property type="entry name" value="SIS_RpiR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000281">
        <property type="entry name" value="HTH_RpiR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035472">
        <property type="entry name" value="RpiR-like_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01418">
        <property type="entry name" value="HTH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51071">
        <property type="entry name" value="HTH_RPIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH rpiR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="2">
        <location>
            <begin position="124"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD63263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW27995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="282" mass="30991" checksum="77D2A302079EA4DF" modified="2016-02-17" version="1">MSPLLKIRSERDQMSAIERRIADYLLENAHLLRDYSSQQLANALGISQSSVVKFSQKLGFKGYPDLKFSIGEAIARGDRHDDGAGAQAAPADPNQALAERLWHGKARAEEETRLINPPERIEAIAELIQHARRVYVIGLGEDGVPARALSMKLAMIGILGIHHFDPVLMAASTASAGAGDVLLVLSEQGKLTSLCHLARSFAESGGRVVSATRHTPNPLRAHADHALLVSAHDERAHVEPLLYHSALQHLLDLIFVLLCERGQDRLRQLDRQAERVQDMLDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMX8</accession>
    <name>A0A0S2DMX8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">4Fe-4S dicluster domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Dmso reductase chain B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FE772_22200</name>
        <name evidence="6" type="ORF">GLE_4547</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949138.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4547"/>
    <dbReference type="EnsemblBacteria" id="ALN59888">
        <property type="protein sequence ID" value="ALN59888"/>
        <property type="gene ID" value="GLE_4547"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4547"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4483"/>
    <dbReference type="OMA" id="CENTPCL"/>
    <dbReference type="OrthoDB" id="1762646at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13247">
        <property type="entry name" value="Fer4_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12800">
        <property type="entry name" value="Fer4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="12"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="85"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="119"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="219"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW27954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="261" mass="28161" checksum="F8304E3AE85ABCB6" modified="2016-02-17" version="1">MTALPPPSKKKLGLVIDLDTCVGCHACAVSCKEWNAGGFAAPLTDERPYGEDPSGVWFNRVHSYELAAQDAPAGGGCGVADAPQPAMTLHFPRSCLHCEQPACVTVCPTGASYKRAEDGIVLVDEDKCIGCKLCSWACPYGAREYSAVEGVMKKCTLCVDRIYNENLSEAERQPACVQACPTRARHFGDLGDPESAVSKLVAERGGVDLMAQLGYQPTNKYLPPRPRRAGQAQADAPQREEALDPQALPTVLRWLDRVLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN06</accession>
    <name>A0A0S2DN06_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF4031 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_14005</name>
        <name evidence="4" type="ORF">FE772_22330</name>
        <name evidence="2" type="ORF">GLE_4575</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000036">
        <property type="protein sequence ID" value="OPD63247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949155.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4575"/>
    <dbReference type="EnsemblBacteria" id="ALN59916">
        <property type="protein sequence ID" value="ALN59916"/>
        <property type="gene ID" value="GLE_4575"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63247">
        <property type="protein sequence ID" value="OPD63247"/>
        <property type="gene ID" value="BV903_14005"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4575"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4511"/>
    <dbReference type="OMA" id="AFERDHY"/>
    <dbReference type="OrthoDB" id="1086845at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025109">
        <property type="entry name" value="DUF4031"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13223">
        <property type="entry name" value="DUF4031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4031" evidence="1">
        <location>
            <begin position="3"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="94" mass="10879" checksum="462B338129F2C9A8" modified="2016-02-17" version="1">MTVYVDDAVWPWRGERWAHLMADTLDELHEFAQRLGKPRVSFQDKPSGCHYDVTARMRERALALGAVAISRHRDRAQVRAIIQRARDQAARRAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN51</accession>
    <name>A0A0S2DN51_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase sigma factor, sigma-70 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Sigma-70 family RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_22745</name>
        <name evidence="4" type="ORF">GLE_4669</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949225.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60010">
        <property type="protein sequence ID" value="ALN60010"/>
        <property type="gene ID" value="GLE_4669"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4669"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4605"/>
    <dbReference type="OMA" id="TWREMQG"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="150"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW28039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="209" mass="23859" checksum="A07D1EE08E8607B0" modified="2016-02-17" version="1">MDANGRERVDTEQFRPAPAGAAQDRGAAGGPCADFKLADQMFTEAWRSNLPELEARARRFAEGQRDRAEELLGNAAIKALLFMRRAPHTITDPGGFLFVVLRHVFLDSVRQRSRDREVFDRHREVDGEGGGFAHEGLSALQKLELEEQLERVVAAVARMSRKQRRLFAYRFVEELPYPVIAERLEMNQPLARKHVELLRNRLRVAVGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN77</accession>
    <name>A0A0S2DN77_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4677</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="ALN60018"/>
        <property type="gene ID" value="GLE_4677"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4677"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4613"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="37" mass="4013" checksum="E6491D8870118EC4" modified="2016-02-17" version="1">MRIESNIAKHNAQGHSPAAFACASIPRGRGRDTRTPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNE3</accession>
    <name>A0A0S2DNE3_LYSEN</name>
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        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_4753</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949289.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4753"/>
    <dbReference type="EnsemblBacteria" id="ALN60094">
        <property type="protein sequence ID" value="ALN60094"/>
        <property type="gene ID" value="GLE_4753"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4753"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4687"/>
    <dbReference type="OrthoDB" id="935411at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="216"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN60094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="414" mass="44468" checksum="32851187112D2954" modified="2016-02-17" version="1">MPRARERLLRGLHLRLSAVWTLAWLLCVAALCAVAIATHARLAQLDLASSLRLRATAVYGLTWFDAQGRFHDETARKEPGLLDADADVWVIGNGEPAKVLLAPKRPRFDLADPFASADAALRDGPEGALEGRDRGGRPYLLQAKETYDERDRPVATILVLADPAARDDAQAAFVRRTLLIALGFALFGVLVGHWLSRRSLRPAIASFEQQERFLAAAAHELRTPVARLQALCETAHDGSEPAAQVLAKVERVAAQTAGLVDKLLLLARLDASAAPASKEPVRLDLLVEAILPEDREIEFHAAESVVNADVRLIQTAVRNLIENALVHSARTDAAASVAVAVEAGKVIVEDRGPGFPADRLARLREPFVSGPGSPGSGLGLSIVQHVAQLHGGELRLSNRPGGGARAELVLRERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNK2</accession>
    <name>A0A0S2DNK2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metal dependent phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4379</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949005.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4379"/>
    <dbReference type="EnsemblBacteria" id="ALN59720">
        <property type="protein sequence ID" value="ALN59720"/>
        <property type="gene ID" value="GLE_4379"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4379"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4318"/>
    <dbReference type="OMA" id="FVWASEV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="32"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="181" mass="20246" checksum="D6DF2781997195AA" modified="2016-02-17" version="1">MTHDHGSVLRAAAFAAQRHRRQRRHDAERSPYINHPLALADTLANLGGIADPVVLCAALLHDTVEDTATTLEEIELAFGARVAAVVAQVSDDKSLPKDERKRLQIEHARHISPEARLVKLADKICNLRDLLQSPPPWTRQRKREYFDWAAQVVAGLRGVHPVLEEEFDAVYARIDELGDSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNL0</accession>
    <name>A0A0S2DNL0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphate-selective porin O and P</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Porin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_23265</name>
        <name evidence="2" type="ORF">GLE_4781</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW28134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949311.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4781"/>
    <dbReference type="EnsemblBacteria" id="ALN60122">
        <property type="protein sequence ID" value="ALN60122"/>
        <property type="gene ID" value="GLE_4781"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4781"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4715"/>
    <dbReference type="OMA" id="FRWGVSA"/>
    <dbReference type="OrthoDB" id="1578713at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010870">
        <property type="entry name" value="Porin_O/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07396">
        <property type="entry name" value="Porin_O_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726821" evidence="1">
        <location>
            <begin position="26"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="398" mass="43957" checksum="B64758ABD9930E0E" modified="2016-02-17" version="1">MAVAPHAGACVALCLIAASAGSVAAAEGADDRPVTAELGGRIHWDFAEFDNDRRGAPNPDDTEVRRLWLDVSGKFYGWGYKIEGDFAGLQDEFKGDSVEAKDVYVTRDFKAGKLTVGQFKQYFTLDDRISSNYGVFMERSMFASSVAPLYRLGAAWITAHDDYTIGGSVYSLESIDVWQVKGRAFGARGTWAPRHDSGDALHLGLSLAREYYDHPGRDGANGLRIAPRPAGHLSDNSRATLVNFNRGLDTDVDKYSLEFALARGPVYVQSELSGADFDDGSQRGEIRSAYATVGWFITGENMPYDTKSGRFGRVKPSRPNGAWVVAARYDTIRGKQHLNGAADFSDVSMEQTSVGVNWHLRANLRFMLDWIESRNRNRLAGVTLDRTRAVTGRFQYDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNN7</accession>
    <name>A0A0S2DNN7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase, group 2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4776</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949307.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4776"/>
    <dbReference type="EnsemblBacteria" id="ALN60117">
        <property type="protein sequence ID" value="ALN60117"/>
        <property type="gene ID" value="GLE_4776"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4776"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4710"/>
    <dbReference type="OMA" id="LVNFRRH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="18"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="334" mass="37671" checksum="286225F3B31D4A74" modified="2016-02-17" version="1">MSALPVLESVAEPRPRVSVLLLCFRDADYIRAALDSAFAQTVPCEIIVSNDCSGDGTFEIAEELVAAYRGPHRVHVRKTERNLGVSAHFNDVMALASGEIIVMMAGDDIAYPERVATIVRAFDEHPGATVLGSDFDAIGSHGEPIQVSFRQRPQRYDFDYYVRIGRLIGLLGATMAFRREVYDRFGPLLGPIEDNALSLRGALLGQSLNLRQPLIQYRRHPGSVSGTVFARDEPRALATRRRYERTVQFYRGTADDLEACLRKMPELPRSKRRLAEQVLAMYRIEADAREAILLQPRWRWLGPVLRGLGQRGLRRKSAERALKLLLPRSWFGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNT4</accession>
    <name>A0A0S2DNT4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4758</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60099">
        <property type="protein sequence ID" value="ALN60099"/>
        <property type="gene ID" value="GLE_4758"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4758"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4691"/>
    <dbReference type="OMA" id="NQSGRYY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="250"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="44"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="637" mass="70325" checksum="2145724B26480EC2" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNU7</accession>
    <name>A0A0S2DNU7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60061">
        <property type="protein sequence ID" value="ALN60061"/>
        <property type="gene ID" value="GLE_4720"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4720"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4654"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="40" mass="4337" checksum="70E525556C7AC994" modified="2016-02-17" version="1">MSAAATAPGPGGASFGSRRFAFWVAHPYLRRHSGENHHPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP02</accession>
    <name>A0A0S2DP02_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_23165</name>
        <name evidence="2" type="ORF">GLE_4764</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949298.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60105">
        <property type="protein sequence ID" value="ALN60105"/>
        <property type="gene ID" value="GLE_4764"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4764"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4697"/>
    <dbReference type="OrthoDB" id="1611442at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="372" mass="41716" checksum="E2C05AB7ECE1164C" modified="2016-02-17" version="1">MSTRERDFLESNRSFQAMPDHIRGWILASPNATADFATFFEKGGTIQADPNQSKPLYRPSSPPSIVVNESEWAALRQYGTNPWPQRHMFGMLAHEIGHDKDNTTRPFPAGGSRDEYVQYRSEIEATAIFNAFPIFKDLKDTPEFSKEAPFDSIGYLHGIELAKLYREWNAGELNDKQVVSAIASKVADTRYTLGGPLSDQDGNGVLTHRDAYLQDFEHVLRPKSEAQPSGRGSDDEPKRPQLNDHGRANPEDTLWQNTREKTQEAFAQHGIKPSDQALDCIAGCLSTQARRDGLDRIDHVLLSQHPDGEIGRNVIAVEGHLDDPSHKRSHVNTKAAENVSLEESMRNLATLDAQRNQQPTREAESVDRPLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPB0</accession>
    <name>A0A0S2DPB0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transglycosylase SLT domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4651</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4651"/>
    <dbReference type="EnsemblBacteria" id="ALN59992">
        <property type="protein sequence ID" value="ALN59992"/>
        <property type="gene ID" value="GLE_4651"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4651"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4587"/>
    <dbReference type="OMA" id="AWHLRQK"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008258">
        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595504" evidence="1">
        <location>
            <begin position="19"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="SLT" evidence="2">
        <location>
            <begin position="20"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="194" mass="20412" checksum="9512A50C4AAA8388" modified="2016-02-17" version="1">MAPSLALAALLASAPAAADCIDDAARYQGVHPHVLRAIAYHESRMKPETVNHNKNSTRDIGLMGINTVHGGELSRYGIGPDRLFDPCVNAYVGAWLLRRKVDKYGATWKAVAAYHSETPQIGEAYMRRIQDVMRRWGLLPAVATAAPKPAPAAAQSSANATSEAMAAAAAVAPVATQAATQNGGGELDALATIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPC9</accession>
    <name>A0A0S2DPC9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RecBCD enzyme subunit RecD</fullName>
            <ecNumber evidence="10">3.1.11.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Exonuclease V subunit RecD</fullName>
            <shortName evidence="10">ExoV subunit RecD</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Helicase/nuclease RecBCD subunit RecD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 12" type="primary">recD</name>
        <name evidence="12" type="ORF">GLE_5230</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Exonucleolytic cleavage (in the presence of ATP) in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides.</text>
            <dbReference type="EC" id="3.1.11.5"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the RecD family.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.5" evidence="10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949650.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5230"/>
    <dbReference type="EnsemblBacteria" id="ALN60571">
        <property type="protein sequence ID" value="ALN60571"/>
        <property type="gene ID" value="GLE_5230"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5230"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5148"/>
    <dbReference type="OMA" id="MIDLEMM"/>
    <dbReference type="OrthoDB" id="961809at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009338">
        <property type="term" value="C:exodeoxyribonuclease V complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008854">
        <property type="term" value="F:exodeoxyribonuclease V activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01487">
        <property type="entry name" value="RecD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006344">
        <property type="entry name" value="RecD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041851">
        <property type="entry name" value="RecD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027785">
        <property type="entry name" value="UvrD-like_helicase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13538">
        <property type="entry name" value="UvrD_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01447">
        <property type="entry name" value="recD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 10" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 10 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 10" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD_C_2" evidence="11">
        <location>
            <begin position="560"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="172"/>
            <end position="179"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN60571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="632" mass="67091" checksum="AB3465553BF3948F" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPF7</accession>
    <name>A0A0S2DPF7_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_24920</name>
        <name evidence="2" type="ORF">GLE_5141</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949584.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5141"/>
    <dbReference type="EnsemblBacteria" id="ALN60482">
        <property type="protein sequence ID" value="ALN60482"/>
        <property type="gene ID" value="GLE_5141"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5141"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5066"/>
    <dbReference type="OMA" id="ADMYATS"/>
    <dbReference type="OrthoDB" id="1983082at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="151" mass="16982" checksum="BC966740C2F05EE0" modified="2016-02-17" version="1">MYIREGQLDRPEVIALLREHLQGMAELSPPESIHALDLDGLKHPRISLWSVWDGGELLGCGALKQLDAEHGEIKSMRTADAHRRRGVAAAMLEHILDEAARRAYRRLSLETGSMEGFGPARSLYARYGFDYCGPFADYRDDPHSVFMSKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPH0</accession>
    <name>A0A0S2DPH0_LYSEN</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5143</name>
    </gene>
    <organism evidence="1 2">
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        <lineage>
            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60484">
        <property type="protein sequence ID" value="ALN60484"/>
        <property type="gene ID" value="GLE_5143"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5143"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="38" mass="3943" checksum="215746176DA508EA" modified="2016-02-17" version="1">MVLDELFDVFEGHVPGSGMSKGESDNAGPCCACMCACM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPJ9</accession>
    <name>A0A0S2DPJ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acetyl-CoA acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_5043</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5043"/>
    <dbReference type="EnsemblBacteria" id="ALN60384">
        <property type="protein sequence ID" value="ALN60384"/>
        <property type="gene ID" value="GLE_5043"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5043"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4971"/>
    <dbReference type="OMA" id="DIYEIHE"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="3">
        <location>
            <begin position="10"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="4">
        <location>
            <begin position="288"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="1">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="385"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="428" mass="45697" checksum="11686F5FFC042ABF" modified="2016-02-17" version="1">MLPMRQNRPVAVLGGVRIPFCRQNTAYADVGNLGMSVRTLGALVEKFGLHGQQLGEVAMGAVIKHSSDWNLGREAALSSGLSPLTPGITLQRACGTSLDSIITIANKIATGQIEAGIGGGSDTTSDVPIVYGKSLRRRLLTAARAKTTKDKLAAFKGFHLRELKPEFPGVAEPRTGKSMGDHCEDMAKQWNISRDSQDEWALSSHQKLAAAYERGFFDDLVVSFRGVSRDNVLRADSTLEKLATLKPAFDKTSGRGTLTAANSTPLTDGAAACLLASEEWAQAHNQEVLCYLRDAQVAAVDFVHGEGLLMAPTVAVPEMLKRNGLTLQDFDIYEIHEAFAAQVLCTLRAWESEDYCKNRLGLDAPLGRIDPAKINPNGSSLAAGHPFAATGARIVATAAKELKQRGGGRCLISICTAGGMGVVAILER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-06-17" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ30</accession>
    <name>A0A0S2DQ30_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_00195</name>
        <name evidence="1" type="ORF">GLE_5383</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949765.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60724">
        <property type="protein sequence ID" value="ALN60724"/>
        <property type="gene ID" value="GLE_5383"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5383"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5298"/>
    <dbReference type="OMA" id="KINQSHY"/>
    <dbReference type="OrthoDB" id="1986905at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="110" mass="12327" checksum="7F544DFAC0B9E1D0" modified="2016-02-17" version="1">MVTRIDPAAYDPAGKDEAVRAACAKWTLDAKQATKFFRASREYPDGTHDAFYWLPCSIKGRLRAQGREWDFEINAAATATWIDGDTARRWGCTDKACEPLVLLMPDGNQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQH7</accession>
    <name>A0A0S2DQH7_LYSEN</name>
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        <submittedName>
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        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">GLE_5384</name>
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        <name type="scientific">Lysobacter enzymogenes</name>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949766.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5384"/>
    <dbReference type="EnsemblBacteria" id="ALN60725">
        <property type="protein sequence ID" value="ALN60725"/>
        <property type="gene ID" value="GLE_5384"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5384"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5299"/>
    <dbReference type="OrthoDB" id="1584054at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06583">
        <property type="entry name" value="PGRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036505">
        <property type="entry name" value="Amidase/PGRP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002502">
        <property type="entry name" value="Amidase_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01510">
        <property type="entry name" value="Amidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00644">
        <property type="entry name" value="Ami_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55846">
        <property type="entry name" value="SSF55846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetylmuramoyl-L-alanine amidase" evidence="1">
        <location>
            <begin position="127"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="320" mass="34227" checksum="740E0C7CA2D0C0F5" modified="2016-02-17" version="1">MGTPSFPYDAAHPDHAQFQRTYDAVKAAGPWSDAQARNLAAGLYAELKQHPQMAGFDRVVAGSADAPVPSLFALRGDPSSPAAQRVGVPLSLREVDAAQTLAGYVHASQVDKNGYLEDPAIKRQPIAALEKGAIDAHHGIVMHRTESATAKSALDAFKSGTGTHFLIDKDGTIYQTASLDQKTYHVGKIKGRCVEEGNCSAQEQAWFDKTGWNPKAVHDHEKAKAYPDRFPMNDDSVGIEVVGSYNAKTKTWDAPTAAQTASINKLVGALQKEYGLDDKDVYKHDAISYKTQGEGADLYVPAAANAPAVDGGVQSAAPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQN1</accession>
    <name>A0A0S2DQN1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptidase, families S8 and S53/proprotein convertase P-domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_00585</name>
        <name evidence="7" type="ORF">GLE_5475</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949834.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60816">
        <property type="protein sequence ID" value="ALN60816"/>
        <property type="gene ID" value="GLE_5475"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5475"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5390"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04059">
        <property type="entry name" value="Peptidases_S8_Protein_convertases_Kexins_Furin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034182">
        <property type="entry name" value="Kexin/furin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002884">
        <property type="entry name" value="P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
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    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01483">
        <property type="entry name" value="P_proprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51829">
        <property type="entry name" value="P_HOMO_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
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    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242287" evidence="5">
        <location>
            <begin position="27"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="P/Homo B" evidence="6">
        <location>
            <begin position="459"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN60816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW24384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="587" mass="61499" checksum="6463F1C7F0D59338" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DR05</accession>
    <name>A0A0S2DR05_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_00650</name>
        <name evidence="4" type="ORF">GLE_5488</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5488"/>
    <dbReference type="EnsemblBacteria" id="ALN60829">
        <property type="protein sequence ID" value="ALN60829"/>
        <property type="gene ID" value="GLE_5488"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5488"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5403"/>
    <dbReference type="OMA" id="KNTYDAD"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="566"/>
            <end position="785"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW24395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="788" mass="88583" checksum="DF63F8313E2C6B76" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DRS6</accession>
    <name>A0A0S2DRS6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0010</name>
        <name evidence="2" type="ORF">GLE_5547</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55369">
        <property type="protein sequence ID" value="ALN55369"/>
        <property type="gene ID" value="GLE_0010"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60888">
        <property type="protein sequence ID" value="ALN60888"/>
        <property type="gene ID" value="GLE_5547"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0010"/>
    <dbReference type="KEGG" id="lez:GLE_5547"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.14"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="49" mass="5735" checksum="AE7B81260785A55E" modified="2016-02-17" version="1">MIFSPESIDRPFLKLFKIQQRVVRTARSTDQLIQLDLDCLGIAVLRILY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA17</accession>
    <name>A0A0S2DA17_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-turn-helix domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_01050</name>
        <name evidence="2" type="ORF">GLE_0023</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945735.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0023"/>
    <dbReference type="EnsemblBacteria" id="ALN55382">
        <property type="protein sequence ID" value="ALN55382"/>
        <property type="gene ID" value="GLE_0023"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0023"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.30"/>
    <dbReference type="OMA" id="ARWNISH"/>
    <dbReference type="OrthoDB" id="2076478at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_17" evidence="1">
        <location>
            <begin position="6"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="71" mass="8256" checksum="C4080B7D8947049B" modified="2016-02-17" version="1">MSSNNLTPEQLAERWDIKPETLQRWRCEKVGPRFFKVERRIRYRLEDIVAYENRSLRSSTTSAAGAAEVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAT3</accession>
    <name>A0A0S2DAT3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0208</name>
        <name evidence="2" type="ORF">GLE_2129</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55567">
        <property type="protein sequence ID" value="ALN55567"/>
        <property type="gene ID" value="GLE_0208"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57479">
        <property type="protein sequence ID" value="ALN57479"/>
        <property type="gene ID" value="GLE_2129"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0208"/>
    <dbReference type="KEGG" id="lez:GLE_2129"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2093"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="37" mass="4284" checksum="C6B12DAC830758B2" modified="2016-02-17" version="1">MLDPVAFDSKKKRPFLWLLSLWLQTKKVTRPLADGSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAU1</accession>
    <name>A0A0S2DAU1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protoheme IX farnesyltransferase</fullName>
            <ecNumber evidence="9">2.5.1.141</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Heme B farnesyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Heme O synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 10" type="primary">cyoE</name>
        <name evidence="11" type="ORF">FE772_02300</name>
        <name evidence="10" type="ORF">GLE_0295</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>(2E,6E)-farnesyl diphosphate + H2O + heme b = diphosphate + Fe(II)-heme o</text>
            <dbReference type="Rhea" id="RHEA:28070"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="ChEBI" id="CHEBI:60530"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.141"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Porphyrin-containing compound metabolism; heme O biosynthesis; heme O from protoheme: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="9">Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.141" evidence="9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945934.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0295"/>
    <dbReference type="EnsemblBacteria" id="ALN55653">
        <property type="protein sequence ID" value="ALN55653"/>
        <property type="gene ID" value="GLE_0295"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0295"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.294"/>
    <dbReference type="OMA" id="MYLKRAT"/>
    <dbReference type="OrthoDB" id="1875497at2"/>
    <dbReference type="UniPathway" id="UPA00834">
        <property type="reaction ID" value="UER00712"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008495">
        <property type="term" value="F:protoheme IX farnesyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048034">
        <property type="term" value="P:heme O biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13957">
        <property type="entry name" value="PT_UbiA_Cox10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00154">
        <property type="entry name" value="CyoE_CtaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006369">
        <property type="entry name" value="Protohaem_IX_farnesylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030470">
        <property type="entry name" value="UbiA_prenylTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43448">
        <property type="entry name" value="PTHR43448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01473">
        <property type="entry name" value="cyoE_ctaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00943">
        <property type="entry name" value="UBIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="273"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN55653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW24675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="310" mass="34029" checksum="4E568B61A5A15BF8" modified="2016-02-17" version="1">MSAAPRPTAKQYWDLTKPRVVALIVFTAIVGMFMAVPGWPPLRESVLGFLGIWLAASSAAAINQLLDSRIDAKMARTSWRPIVAGQVTPRQALVFALSLAAASMAILVLWVNAITALLTFASLIGYAVVYTVYLKRATPQNIVIGGIAGAAPPLLGWAAVTGMQGEWDWAHALLLVLIIFVWTPPHFWALAIFRRADYARAMVPMLPVTHGVQYTRWQILFYTVLLVAVTVLPWAAGMSGLFYLGGALVLGAMFLYYAWKLMDPPDELYAMKVFNYSIVYLMALFAFLLADHWLLPALQPAAAFELRAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAV0</accession>
    <name>A0A0S2DAV0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">VanZ like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0317</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0317"/>
    <dbReference type="EnsemblBacteria" id="ALN55675">
        <property type="protein sequence ID" value="ALN55675"/>
        <property type="gene ID" value="GLE_0317"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0317"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.314"/>
    <dbReference type="OMA" id="MADPMDA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="136" mass="14563" checksum="CA0DA3CAD200F291" modified="2016-02-17" version="1">MSAARTLREFRRPALWIALWLAMIAAVIATCLMPAQDLPPAPFDAFDKVEHFTAYLLLSLYAGMLFARVRAQALAAAGLIALGIALEFAQANLTDSRSGDAADALANGLGALAGLWLSRTPVALWLQRLDRALARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB02</accession>
    <name>A0A0S2DB02_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidase M23</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Peptidase, family M23/M37 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BV903_24370</name>
        <name evidence="4" type="ORF">GLE_0273</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000093">
        <property type="protein sequence ID" value="OPD61300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945918.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000093.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0273"/>
    <dbReference type="EnsemblBacteria" id="ALN55631">
        <property type="protein sequence ID" value="ALN55631"/>
        <property type="gene ID" value="GLE_0273"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61300">
        <property type="protein sequence ID" value="OPD61300"/>
        <property type="gene ID" value="BV903_24370"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0273"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.272"/>
    <dbReference type="OMA" id="WPATIRY"/>
    <dbReference type="OrthoDB" id="1891666at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594861" evidence="2">
        <location>
            <begin position="25"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="3">
        <location>
            <begin position="322"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN55631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD61300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="421" mass="45637" checksum="EB7F3AF01EE3E5A3" modified="2016-02-17" version="1">MRIACAWMLALLAALPLAAPPARAAAQQGSSRETERKLEKIKTELKSVAAERRKLEGQRGDAAQKLRAADEQVGRSNRVLRDTETRLAREHAALKQTQDQRDSLKKNLGARRKELEQLLRAAYAQGNDAPLKALLSQDRVADSGRILTYHGYLQRDRARRIDELTAQLRELDRLEREIVERRASLDSTRKQQRAQLGQLEKDRKDRAVLVAQINEKYEDRSTRERELGRDAKGLEQLLAKLRAAAARAEAQRRAAAKARAEREAREARAAAAAAAKGKPAPVRKPPVAVASAPAPQVGGLGWPVSGALLAGFGGTMPDGRSSEGLLIGAPAGATVKAVGDGTVVYSEWMTGYGLLLIVDHGNGYMSLYANNDALLKDAGATVKKGDAVATVGSSGGHGRPALYFELRRGGQPVNPGVWLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB31</accession>
    <name>A0A0S2DB31_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Calcium-binding EF-hand</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">EF-hand domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_02755</name>
        <name evidence="3" type="ORF">GLE_0393</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945999.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0393"/>
    <dbReference type="EnsemblBacteria" id="ALN55751">
        <property type="protein sequence ID" value="ALN55751"/>
        <property type="gene ID" value="GLE_0393"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0393"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.390"/>
    <dbReference type="OrthoDB" id="1913389at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="SSF47473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242255" evidence="1">
        <location>
            <begin position="20"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="59"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="97"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="125" mass="13459" checksum="254110ECF3CF1789" modified="2016-02-17" version="1">MKNAIVLVALSAVAAVANAAPSDPKQTYIDATFSAMDANKDGRVDKSEYAKFQNSRFNQQAESVDAAFKEMDKDGDGKVSKKEAAIVPEIAKYFDGLDSDRDGFLSLKEMQQAMVAAQTADASKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB91</accession>
    <name>A0A0S2DB91_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_02965</name>
        <name evidence="2" type="ORF">GLE_0437</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946034.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0437"/>
    <dbReference type="EnsemblBacteria" id="ALN55795">
        <property type="protein sequence ID" value="ALN55795"/>
        <property type="gene ID" value="GLE_0437"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0437"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.434"/>
    <dbReference type="OMA" id="DHQGSYN"/>
    <dbReference type="OrthoDB" id="606679at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="546" mass="59061" checksum="8A54BD9E2B4385A0" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB93</accession>
    <name>A0A0S2DB93_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">Type IV / VI secretion system protein, DotU family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0443</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0443"/>
    <dbReference type="EnsemblBacteria" id="ALN55801">
        <property type="protein sequence ID" value="ALN55801"/>
        <property type="gene ID" value="GLE_0443"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0443"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.441"/>
    <dbReference type="OMA" id="MLRHEVP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017732">
        <property type="entry name" value="T4/T6SS_DotU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038522">
        <property type="entry name" value="T4/T6SS_DotU_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09850">
        <property type="entry name" value="DotU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03349">
        <property type="entry name" value="IV_VI_DotU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="DotU" evidence="2">
        <location>
            <begin position="20"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="250" mass="27595" checksum="67DAAD7FA6DFFE40" modified="2016-02-17" version="1">MPSLGPSQSAPAPASAPARSLLDLMSDGFYLLMLLKRGQLPSAEAPFVESIKRFLDGTERGAVKLGIGTEDVYAAKYAFCAALDEAILSQPSDLREEWERNPLQLRLFGEHLAGEHFFDRLEQLRAQGAPRLPSLEVYYYCLLLGFEGKYRLEGPEKLGYLTARLGDEIAYLKGKRAPFAPHWAPPDRIQHALRRVTPIWAPVAVVGIGAVLAFLAFSTLAARDTNRQLAQYNDVVQMPADTAQLTITLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBK9</accession>
    <name>A0A0S2DBK9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_03505</name>
        <name evidence="1" type="ORF">GLE_0555</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946122.1">
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55913">
        <property type="protein sequence ID" value="ALN55913"/>
        <property type="gene ID" value="GLE_0555"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0555"/>
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    <dbReference type="OrthoDB" id="2099123at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="115" mass="12387" checksum="6E79CA710FA5D19F" modified="2016-02-17" version="1">MQWDAIVAVVRELRLKARVKPRGSPPPPEWTTFLIVPVPGYVESSGCGPLPFREVEWIEIDPVRVTERGRLLAPAVENLAGELLSRLTALGLQAQGGEGAKVRVAAGEPNARPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBQ4</accession>
    <name>A0A0S2DBQ4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_15630</name>
        <name evidence="4" type="ORF">FE772_03715</name>
        <name evidence="2" type="ORF">GLE_0603</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000040">
        <property type="protein sequence ID" value="OPD63060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946154.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55961">
        <property type="protein sequence ID" value="ALN55961"/>
        <property type="gene ID" value="GLE_0603"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63060">
        <property type="protein sequence ID" value="OPD63060"/>
        <property type="gene ID" value="BV903_15630"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0603"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.595"/>
    <dbReference type="OrthoDB" id="1890830at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594725" evidence="1">
        <location>
            <begin position="26"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="193" mass="19719" checksum="A947DEBCFF83DECE" modified="2016-02-17" version="1">MSKLKYSILALVSAAAICGATSAAAAPGTFLLWNGTSWVNNGQVTFTGRTTASYLQLQLPCDQATFVVDVVNGNAKVSAATFAGSSACTKIVAQNLPWSMVPDTVYTGSNPPFPGAPTLNGPLYGVTISGIRIYLPLPLNVTCPNATGSGSISGALDSSFPANRFAFQGALGPCGVQTQAGYYLSSSVPVTVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC09</accession>
    <name>A0A0S2DC09_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Glutamine--fructose-6-phosphate aminotransferase [isomerizing]</fullName>
            <ecNumber evidence="2 8">2.6.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">GFAT</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Glucosamine-6-phosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Hexosephosphate aminotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">L-glutamine--D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">glmS</name>
        <name evidence="12" type="ORF">FE772_04185</name>
        <name evidence="11" type="ORF">GLE_0702</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:13237"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="2.6.1.16"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.6.1.16" evidence="2 8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946230.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0702"/>
    <dbReference type="EnsemblBacteria" id="ALN56060">
        <property type="protein sequence ID" value="ALN56060"/>
        <property type="gene ID" value="GLE_0702"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0702"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.690"/>
    <dbReference type="OMA" id="GTSHYAG"/>
    <dbReference type="OrthoDB" id="43416at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901137">
        <property type="term" value="P:carbohydrate derivative biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00164">
        <property type="entry name" value="GlmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005855">
        <property type="entry name" value="GlmS_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <source>
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        <source>
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        <source>
            <dbReference type="EMBL" id="QCW25079.1"/>
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    </evidence>
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        <source>
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        <source>
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    </evidence>
    <sequence length="1054" mass="116827" checksum="8123D891E0F193E4" modified="2016-02-17" version="1"> </sequence>
</entry>
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    <accession>A0A0S2DCC2</accession>
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        <submittedName>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="39" mass="4444" checksum="30F1857F15834178" modified="2016-02-17" version="1">MPRLSPKLRMHAGLYRLXXXXXXXSFGASVGRGSRRSYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCH1</accession>
    <name>A0A0S2DCH1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">5-formyltetrahydrofolate cyclo-ligase</fullName>
            <ecNumber evidence="3">6.3.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BV903_19625</name>
        <name evidence="6" type="ORF">FE772_05085</name>
        <name evidence="4" type="ORF">GLE_0884</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">C3</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(6S)-5-formyl-5,6,7,8-tetrahydrofolate + ATP = 5,10-methenyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10488"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.2" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000057">
        <property type="protein sequence ID" value="OPD62204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946368.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000057.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0884"/>
    <dbReference type="EnsemblBacteria" id="ALN56242">
        <property type="protein sequence ID" value="ALN56242"/>
        <property type="gene ID" value="GLE_0884"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62204">
        <property type="protein sequence ID" value="OPD62204"/>
        <property type="gene ID" value="BV903_19625"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0884"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.873"/>
    <dbReference type="OMA" id="MPLVGFD"/>
    <dbReference type="OrthoDB" id="1816478at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030272">
        <property type="term" value="F:5-formyltetrahydrofolate cyclo-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002698">
        <property type="entry name" value="FTHF_cligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23407:SF1">
        <property type="entry name" value="PTHR23407:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01812">
        <property type="entry name" value="5-FTHF_cyc-lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006806">
        <property type="entry name" value="FTHF_cligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02727">
        <property type="entry name" value="MTHFS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="5"/>
            <end position="9"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="133"/>
            <end position="141"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006806-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD62204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW25132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="197" mass="21781" checksum="FF3051C682BD3B7F" modified="2016-02-17" version="1">MTDDRTTLRRELRARRRNLPAAARIGGAEALAAQLLALPFAPPSGYVAGYWAMDGEIALHAWQLRLPRDCVYCLPVLHADQRLRFAPWRPGDPLAANRFGIPEPALAPESLLEPEQMSLIVLPLVGFDGRGHRLGMGGGWYDRSLAFRQRRPAPPWLVGAGFELQRVERLDAADWDVALDAVCTEAGTVDCRSALYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCH4</accession>
    <name>A0A0S2DCH4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endo-beta-N-acetylglucosaminidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0844</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946339.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0844"/>
    <dbReference type="EnsemblBacteria" id="ALN56202">
        <property type="protein sequence ID" value="ALN56202"/>
        <property type="gene ID" value="GLE_0844"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0844"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.833"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50022">
        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F5/8 type C" evidence="1">
        <location>
            <begin position="16"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="175" mass="19207" checksum="39602A631F1DDCFB" modified="2016-02-17" version="1">MNDANLAIARAIVVACAALAVAWPRPGAAGDGGSRGENYALNRPATASPICKPGEEAGKAFDGRLSSKTEHKYCTLQRPAWLQVDLQQRRRVREFVLKHAGAGGEPAAMNTRAYALSLSDDGEHWRPAVRVRDNRRSVRRHAIAPTWARYVRLEVSEPAQAPADPATRIYELEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCM1</accession>
    <name>A0A0S2DCM1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type IV pilus assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pilN</name>
        <name evidence="4" type="ORF">GLE_0933</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946405.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0933"/>
    <dbReference type="EnsemblBacteria" id="ALN56291">
        <property type="protein sequence ID" value="ALN56291"/>
        <property type="gene ID" value="GLE_0933"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0933"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.921"/>
    <dbReference type="OMA" id="LETSGWM"/>
    <dbReference type="OrthoDB" id="1673053at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007813">
        <property type="entry name" value="PilN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05137">
        <property type="entry name" value="PilN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="211"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="57"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="250"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="282" mass="28902" checksum="D1B7087A4DBC2987" modified="2016-02-17" version="1">MARINLLPWRAERRKARQKEFGAMLGLSALAAAALSFLIVFYYSNEISGQEKRNSFLDGQIAEVDKKIAEIEELDKKKAKLLARKEVIEKLQSNRSQMVHLFDSLVRTIPDGAVLTAIKQDAETLTLEGRAQSNARVSTYMRNLEVSGWMSKPDLTIIEAKDGGGKGLPYEFKLTVKLANPNAPKDEDGDGIPDAPAAPAEAAAANAPVAAAGPAPAGAAPAAAAPAANAPAAPGSAPAAPAAAKPGQAPAAPAQPPAAKPAAAPAKPAAPAAAPTKTGAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCW0</accession>
    <name>A0A0S2DCW0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Efflux transporter periplasmic adaptor subunit</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">RND efflux membrane fusion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BV903_12530</name>
        <name evidence="5" type="ORF">GLE_0990</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">B25</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000030">
        <property type="protein sequence ID" value="OPD63643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946445.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000030.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0990"/>
    <dbReference type="EnsemblBacteria" id="ALN56348">
        <property type="protein sequence ID" value="ALN56348"/>
        <property type="gene ID" value="GLE_0990"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63643">
        <property type="protein sequence ID" value="OPD63643"/>
        <property type="gene ID" value="BV903_12530"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0990"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.978"/>
    <dbReference type="OMA" id="SVIKLDF"/>
    <dbReference type="OrthoDB" id="1432684at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594843" evidence="3">
        <location>
            <begin position="21"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="58"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="349"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD63643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="373" mass="38688" checksum="D623224021C18F94" modified="2016-02-17" version="1">MRPRPALRSGCLLAFALALAACGKGGQPQAGAGGGPGGGQGDRPIPVTAEPVRLRAWNDTVQALGNVKARESVTVTAKVSEIVQSVHFDSGDHVAAGQSLVTLSGKAQLAALAQAEATAKEAEQLYQRQTELAAQQLIARSALDTQRATRDATRARVEQMKADIGDRQVRAPFAGVLGIRQVSPGALVTPGTPIATLDDTERVYIDFPVPETLLARVAKGQDVTGTSAAYAGKEFHGSVGTVDARVDPTTRAVTVRADFANPGHLLRPGMLVQVTLIQPERQALLVPEISVVQVGNDSYVYRLKPDATVERADVQVGSRRQGLAEILDGLAVGDTIVVDGTGKLRAGSKVQAAGAPAREAGAPSGAAKDGRNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCW2</accession>
    <name>A0A0S2DCW2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Large-conductance mechanosensitive channel</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10 11" type="primary">mscL</name>
        <name evidence="12" type="ORF">BV903_23540</name>
        <name evidence="13" type="ORF">FE772_05605</name>
        <name evidence="11" type="ORF">GLE_1000</name>
    </gene>
    <organism evidence="11 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">C3</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">B25</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homopentamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell inner membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the MscL family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000083">
        <property type="protein sequence ID" value="OPD61449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946453.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000083.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1000"/>
    <dbReference type="EnsemblBacteria" id="ALN56358">
        <property type="protein sequence ID" value="ALN56358"/>
        <property type="gene ID" value="GLE_1000"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61449">
        <property type="protein sequence ID" value="OPD61449"/>
        <property type="gene ID" value="BV903_23540"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1000"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.988"/>
    <dbReference type="OMA" id="AWIIFLM"/>
    <dbReference type="OrthoDB" id="1863650at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00115">
        <property type="entry name" value="MscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019823">
        <property type="entry name" value="Mechanosensitive_channel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001185">
        <property type="entry name" value="MS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037673">
        <property type="entry name" value="MSC/AndL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036019">
        <property type="entry name" value="MscL_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30266">
        <property type="entry name" value="PTHR30266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01741">
        <property type="entry name" value="MscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01264">
        <property type="entry name" value="MECHCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81330">
        <property type="entry name" value="SSF81330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00220">
        <property type="entry name" value="mscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01327">
        <property type="entry name" value="MSCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="21"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN56358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OPD61449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW25212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="135" mass="14458" checksum="87E940373A001BEE" modified="2016-02-17" version="1">MGMISEFKEFIARGNVVDLAVGVVIGAAFGKIVTALVDGIVMPAIGYITGGVSVSDWKYVLKPSQLDAAGKEVAAEVAIKYGMFLQTAIDFILIAFVIFIVLKAYNKVRKPAEAAPAATPEDVLLLREIRDSLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCX5</accession>
    <name>A0A0S2DCX5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Thiamine biosynthesis protein ThiS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">thiS</name>
        <name evidence="1" type="ORF">GLE_1011</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1011"/>
    <dbReference type="EnsemblBacteria" id="ALN56369">
        <property type="protein sequence ID" value="ALN56369"/>
        <property type="gene ID" value="GLE_1011"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1011"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.999"/>
    <dbReference type="OMA" id="DRMEIVC"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010035">
        <property type="entry name" value="Thi_S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34472">
        <property type="entry name" value="PTHR34472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01683">
        <property type="entry name" value="thiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="101" mass="10275" checksum="C059F1C1E3AD3858" modified="2016-02-17" version="1">MRRIQARHAATARAAGDVGSAARLAAPPGNGDNAGMNILLNGEARALVAPVTLLQLLAAEGLGERRVAVEINGEIVPRGRHGETVLAEGDKVEIVHALGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCY7</accession>
    <name>A0A0S2DCY7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-dependent protease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">ATP-dependent protease La (LON) domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_23910</name>
        <name evidence="4" type="ORF">FE772_04965</name>
        <name evidence="2" type="ORF">GLE_0863</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000088">
        <property type="protein sequence ID" value="OPD61381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946352.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000088.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0863"/>
    <dbReference type="EnsemblBacteria" id="ALN56221">
        <property type="protein sequence ID" value="ALN56221"/>
        <property type="gene ID" value="GLE_0863"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61381">
        <property type="protein sequence ID" value="OPD61381"/>
        <property type="gene ID" value="BV903_23910"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0863"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.852"/>
    <dbReference type="OMA" id="ANRWCEL"/>
    <dbReference type="OrthoDB" id="1474822at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="1">
        <location>
            <begin position="9"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="194" mass="21597" checksum="50430C9EA145274A" modified="2016-02-17" version="1">MPTSDADSLGLFPLHTVLLPGASLGLRVFERRYLDLVRECGRLGRGFGVCLIMQGEEVGEPASAAAYGTEALIEDFGTGEDGLLTLRVRGARRFRAERARVRDNGLQVAHVRWCEPDGEEVVRPQHSLLVTLLERLLEQAGGEHALAPHSRLDDAAWVGWRLAELLPLALQQRQMLLQLDDPHERLERLLTLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD72</accession>
    <name>A0A0S2DD72_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 19">Branched-chain-amino-acid aminotransferase</fullName>
            <shortName evidence="19">BCAT</shortName>
            <ecNumber evidence="10 19">2.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19 20" type="primary">ilvE</name>
        <name evidence="21" type="ORF">FE772_05720</name>
        <name evidence="20" type="ORF">GLE_1025</name>
    </gene>
    <organism evidence="20 22">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="20 22" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 22">C3</strain>
        </source>
    </reference>
    <reference evidence="21 23" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 23">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 19">Acts on leucine, isoleucine and valine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 19">
            <text>2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 19">
            <text>2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:18321"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 19">
            <text>2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24813"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 18">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6 19">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8 19">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7 19">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9 17">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="10 19"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946470.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1025"/>
    <dbReference type="EnsemblBacteria" id="ALN56383">
        <property type="protein sequence ID" value="ALN56383"/>
        <property type="gene ID" value="GLE_1025"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1025"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1013"/>
    <dbReference type="OMA" id="LTEVFAC"/>
    <dbReference type="OrthoDB" id="1275805at2"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00058"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00073"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00062"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052656">
        <property type="term" value="F:L-isoleucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052654">
        <property type="term" value="F:L-leucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052655">
        <property type="term" value="F:L-valine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01557">
        <property type="entry name" value="BCAT_beta_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018300">
        <property type="entry name" value="Aminotrans_IV_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005785">
        <property type="entry name" value="B_amino_transI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033939">
        <property type="entry name" value="BCAT_family"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="SSF56752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01122">
        <property type="entry name" value="ilvE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00770">
        <property type="entry name" value="AA_TRANSFER_CLASS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 19" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12 19 20" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="16 19" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="15 18" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14 19 20" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00003109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00004931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00005072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00013053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00018179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU004106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU004516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU364094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ALN56383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="QCW25229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="304" mass="33145" checksum="BC2BD91B2BAAE76F" modified="2016-02-17" version="1">MQYPEWIWQNGSIKRWAEATTHVMSHALHYGSSVFEGIRTYDTPNGPIIFRLNDHNQRLFASAKIYDMPIPYSLAQINAACHEVIKANGHSTDYLRPVAYRGLGGFGLSADTPTDVAVATWKMGQYLGPSVLEEGIDACVSSWQRFAPNTIPAGAKAGGNYLSGQLVAREARRLGFGEGIALASTGLLSEGAGENLFLVFNGALHTTPVSAALLNGLTRNTIITLARDAGIEVVERDLPREYLYLCDELFMCGTAAEITPIRSVDGRQVGSGRRGPVTERIQELFFGLFNGKTADKYGWLEAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD82</accession>
    <name>A0A0S2DD82_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dodecin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_16220</name>
        <name evidence="4" type="ORF">D9T17_21340</name>
        <name evidence="3" type="ORF">FE772_06285</name>
        <name evidence="1" type="ORF">GLE_1152</name>
    </gene>
    <organism evidence="1 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 5">C3</strain>
        </source>
    </reference>
    <reference evidence="2 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">OH11</strain>
        </source>
    </reference>
    <reference evidence="3 8" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000043">
        <property type="protein sequence ID" value="OPD62829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000054">
        <property type="protein sequence ID" value="ROU04930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946557.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000054.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1152"/>
    <dbReference type="EnsemblBacteria" id="ALN56510">
        <property type="protein sequence ID" value="ALN56510"/>
        <property type="gene ID" value="GLE_1152"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62829">
        <property type="protein sequence ID" value="OPD62829"/>
        <property type="gene ID" value="BV903_16220"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1152"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1137"/>
    <dbReference type="OrthoDB" id="2025589at2"/>
    <dbReference type="Proteomes" id="UP000061569">
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="OPD62829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROU04930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="67" mass="7166" checksum="7FABD77A25DE2D7D" modified="2016-02-17" version="1">MSVAKVIELSTSSTTGIEDAVKSGLAKCAESVKDIQGAWVNEIKVTTDAAGNIQEWRVNLKISFVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDP3</accession>
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        <name type="scientific">Lysobacter enzymogenes</name>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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    </dbReference>
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    </dbReference>
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            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
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            <begin position="53"/>
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        <source>
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            <dbReference type="ARBA" id="ARBA00022989"/>
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            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
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        </source>
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            <dbReference type="EMBL" id="ALN56661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="421" mass="42496" checksum="82B9435F5CFADB88" modified="2016-02-17" version="1">MHAPSPSSSATAPTAGGRARLPVALYALTVGAFGIGTTEFVIMGLLLQVAADLQVGLAAAGLLISGYALGVFVGAPVLTVATGRMPRKAVLVALMLIFTVGNIVCAIAPNYTVLMIARVITSLAHGTFFGVGAVVATGLVPQDRKASAISIMFTGLTVATLLGVPAGAWLGLHFGWRSTFWAVAAIGVIATAVIAALVPRDRGKPEPVALRRELRAVLHPQVLLGLAMTVLGFAGVFTVYTFIQPILTRLSGFGEAAVSPILLVFGGGMILGNLVGGRFADQRLAPALIGTLAALAAVLGVMTFALREPIAAVAFVGLLGVAAFATVPPLQLWVLQKTDAAGQNLASSLNIGAFNLGNALGAWLGGAVIERGPGLGAVTWVAALVTVSGLMLALLAAHLDAKGRARAQRGGEPGAAAACAG</sequence>
</entry>
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    <accession>A0A0S2DDU7</accession>
    <name>A0A0S2DDU7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">OsmC family peroxiredoxin</fullName>
        </submittedName>
        <submittedName>
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        </submittedName>
        <submittedName>
            <fullName evidence="2">OsmC/Ohr family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_20810</name>
        <name evidence="4" type="ORF">FE772_06905</name>
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    </gene>
    <organism evidence="2 5">
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        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
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    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000064">
        <property type="protein sequence ID" value="OPD62003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946657.1">
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_1283"/>
    <dbReference type="EnsemblBacteria" id="ALN56640">
        <property type="protein sequence ID" value="ALN56640"/>
        <property type="gene ID" value="GLE_1283"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62003">
        <property type="protein sequence ID" value="OPD62003"/>
        <property type="gene ID" value="BV903_20810"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1283"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1266"/>
    <dbReference type="OMA" id="ANCPVSQ"/>
    <dbReference type="OrthoDB" id="1655733at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
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            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25433.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="143" mass="14923" checksum="ADDC388BE935AAED" modified="2016-02-17" version="1">MGISRHATAHWEGDLKNGQGRLSTPQSGLLDNTRYGFNSRFGEEKGTNPEELIAAAHAGCFTMALSAKLTEAGHPPASLDTRAEVDLSMEGGPSLSQIRLKVKAQVPGIDAAKFQAIAEDAKANCPVSKALAAVPVSLEAVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDX4</accession>
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    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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    <dbReference type="KEGG" id="lez:GLE_1465"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1446"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="47" mass="5257" checksum="9A11228C6A6932B5" modified="2016-02-17" version="1">MEVRWPRAAAPRCARTTADCAGAADWNKEPSPEQPGHVRPLRELVRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE22</accession>
    <name>A0A0S2DE22_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">N-formylglutamate amidohydrolase</fullName>
            <ecNumber evidence="1 2">3.5.1.68</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="2">N-formylglutamate deformylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hutG</name>
        <name evidence="2" type="ORF">FE772_07735</name>
        <name evidence="1" type="ORF">GLE_1471</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="269" mass="29978" checksum="B88BB041C0236E24" modified="2016-02-17" version="1">MNIPAPAWPVFQLHRGHAPLLISLPHDGSMIPDEFSARMVESARHAPDTDWHVSRLYDFARELGASILVPRYSRYVVDLNRPPDDTSLYPGQNTTGLCPAVQFSGEAVYLDGQAPDEAEVAQRVELYWRPYHETLVAELDRIRGEHGRALLWEGHSIRGEVPFLFDGRLPDLSLGTAAGHSCQPATQARLEAVLAGQGEYDWVANGRFKGGYITRHYGDPSIEVEAVQLELSQRNYMDEDSFAYDDAKAAKLQPLLRALLQAALDSQRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEC8</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
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        <name evidence="2" type="ORF">GLE_1562</name>
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    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
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    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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        <property type="gene ID" value="GLE_1562"/>
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    <dbReference type="KEGG" id="lez:GLE_1562"/>
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        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="173" mass="19416" checksum="EE59D32995F4D043" modified="2016-02-17" version="1">MAKKDSAKNDSAKAAKPAAIADKYARKHKRHKPDGKYPTHRIELTVAHVGFGGNAGKGHYFYSFAPDVVTFQGGPVWIEYAFEAQVQERFEIVNVLTSDAFKQIGEPEFEYDKDGEKNVRKVFLFNKNSVSTLIFFTVLVRDRQSNYNDVELISCDPQVGNDPQITPTKGKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEG3</accession>
    <name>A0A0S2DEG3_LYSEN</name>
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        <submittedName>
            <fullName evidence="6">Pirin family protein</fullName>
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        <submittedName>
            <fullName evidence="5">Pirin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_08365</name>
        <name evidence="5" type="ORF">GLE_1608</name>
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    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the pirin family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ALN56965">
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        <property type="gene ID" value="GLE_1608"/>
    </dbReference>
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    <dbReference type="OMA" id="PHPHRGM"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="126"/>
        </location>
    </feature>
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        <location>
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            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW25678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="285" mass="31106" checksum="9EC2B0FD35775042" modified="2016-02-17" version="1">MATTATTYARVGRKLRGQATSDGAGVRLTRVIGGPQLPDLDPFLLLDEFGTDQPEDYLAGFPEHPHRGFETVTYMLDGRMRHRDNHGNEGVLVPGSVQWMTAGRGLVHSEMPEQEQGRMRGFQLWVNLPAREKMTEPKYQEFAPDRIVQLAPADGVRVRLIAGGLGDARGPISQPATDPVYLDVELQPGAAWEYELPEGHNVFAYVYEGGVSVGDGADARAVDAQEMAVLAGGSTLKLADGGRGSRLIVVGGRPLREPVARYGPFVMNTKQEIMQAFVDFQEGKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEY4</accession>
    <name>A0A0S2DEY4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">OmpA/MotB family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Porin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_09205</name>
        <name evidence="3" type="ORF">GLE_1790</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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            <taxon>Proteobacteria</taxon>
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        </lineage>
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    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57143">
        <property type="protein sequence ID" value="ALN57143"/>
        <property type="gene ID" value="GLE_1790"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1790"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1763"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242294" evidence="1">
        <location>
            <begin position="24"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="2">
        <location>
            <begin position="12"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="205" mass="21735" checksum="4036D5D7674FA433" modified="2016-02-17" version="1">MQRTLSALAAAAIAFTLSTAANAQGAGEREGFYAYGGVGAATTQWDAKRSALPAGQKRSQDKGSTSFVLGGGYRFNRYFAVEGSYHDLFGEVSRRGLGDYDTRSLQLSALGILPIGERFEIFGKASVGRARNEFTPVRGAVGLGKASETVNIAALGVGANYHFTDQLALRLDVTGLSKADSAFRRKAGADDIKTGEATLSVMYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEY6</accession>
    <name>A0A0S2DEY6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1727</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57082">
        <property type="protein sequence ID" value="ALN57082"/>
        <property type="gene ID" value="GLE_1727"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1727"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1705"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594920" evidence="2">
        <location>
            <begin position="25"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="58" mass="6181" checksum="96ECDCBD4F72C846" modified="2016-02-17" version="1">MRGSRRSQALALLALAAVPPPAHGSDFSFALFWLGRGVGVFALCALAAWIWAQSRHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEZ6</accession>
    <name>A0A0S2DEZ6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4189 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1792</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57145">
        <property type="protein sequence ID" value="ALN57145"/>
        <property type="gene ID" value="GLE_1792"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1792"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1765"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025240">
        <property type="entry name" value="DUF4189"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13827">
        <property type="entry name" value="DUF4189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4189" evidence="1">
        <location>
            <begin position="141"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="241" mass="25468" checksum="E21AF0A68A846892" modified="2016-02-17" version="1">MAARGDGAMMADRAGGEGRIGVPMIYACRRFSLSVPIRSVSFVPTDVRIRMRASRACRGDFSGASVRAKPRRTGCVRSRRARRRGSLGESDMKQIHYAAWALMLLFAAGAHAQDCAGARARNDPGCARSPVARVAHWESRWGAFALDEAAGLGAASGERSKPSAERAALAACKRKGGRKCALMLSFADQCGALIAADRGSSVAVSPTAQAATELGLSICRRGGLSGCRPYHAQCSPAQWVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEZ7</accession>
    <name>A0A0S2DEZ7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_08040</name>
        <name evidence="1" type="ORF">GLE_1536</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946858.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56893">
        <property type="protein sequence ID" value="ALN56893"/>
        <property type="gene ID" value="GLE_1536"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1536"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1518"/>
    <dbReference type="OMA" id="PAYDEVW"/>
    <dbReference type="OrthoDB" id="2075148at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="183" mass="20525" checksum="3B3553B195147CBB" modified="2016-02-17" version="1">MPEPMPPPRSLYFHEDDDSQIELLPLAAWAHCKRTLADLHDFAEAHFDGAGYTELMVRPDAPHRLAELRLQPGAVAAVAAAQFPAYDEVWTGYSSSRTRCRGVRAWGEDGFALFADGDESSVEGLWLLADRWWPRHAPRIAALLRSLPRAGELLLVDWPWGHLFALSDAPALERWLAERTAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF93</accession>
    <name>A0A0S2DF93_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Imidazole glycerol phosphate synthase subunit HisH</fullName>
            <ecNumber evidence="9">4.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">IGP synthase glutaminase subunit</fullName>
            <ecNumber evidence="9">3.5.1.2</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">IGP synthase subunit HisH</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">ImGP synthase subunit HisH</fullName>
            <shortName evidence="9">IGPS subunit HisH</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 12" type="primary">hisH</name>
        <name evidence="13" type="ORF">BV903_17305</name>
        <name evidence="15" type="ORF">D9T17_17875</name>
        <name evidence="14" type="ORF">FE772_09715</name>
        <name evidence="12" type="ORF">GLE_1901</name>
    </gene>
    <organism evidence="12 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 16">C3</strain>
        </source>
    </reference>
    <reference evidence="13 17" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 17">B25</strain>
        </source>
    </reference>
    <reference evidence="15 18" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 18">OH11</strain>
        </source>
    </reference>
    <reference evidence="14 19" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 19">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 9">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 9">Heterodimer of HisH and HisF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="4.3.2.10" evidence="9"/>
    <dbReference type="EC" id="3.5.1.2" evidence="9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000046">
        <property type="protein sequence ID" value="OPD62689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000044">
        <property type="protein sequence ID" value="ROU05567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947130.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000044.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1901"/>
    <dbReference type="EnsemblBacteria" id="ALN57252">
        <property type="protein sequence ID" value="ALN57252"/>
        <property type="gene ID" value="GLE_1901"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62689">
        <property type="protein sequence ID" value="OPD62689"/>
        <property type="gene ID" value="BV903_17305"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1901"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1869"/>
    <dbReference type="OMA" id="WVYFVHS"/>
    <dbReference type="OrthoDB" id="1726024at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01748">
        <property type="entry name" value="GATase1_IGP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00278">
        <property type="entry name" value="HisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010139">
        <property type="entry name" value="Imidazole-glycPsynth_HisH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42701">
        <property type="entry name" value="PTHR42701"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000495">
        <property type="entry name" value="Amidotransf_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01855">
        <property type="entry name" value="IMP_synth_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 12" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="11">
        <location>
            <begin position="6"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9 10">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <feature type="active site" evidence="9 10">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <feature type="active site" evidence="9 10">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000495-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN57252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OPD62689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW25900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROU05567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="202" mass="21243" checksum="8BECFCFADF36AC3B" modified="2016-02-17" version="1">MTVVAVIDSGGGNIGSVRYALERLGARSVLTADPATIASADRVILPGVGAAAPAMARLRELDLVATIRRLQQPLLGICLGMQLLYESSEEGEVECLGLLPGRITKLPPGPGVRVPHMGWNLLQKHESNAGARLLAGIGERDQAYFVHSYAAPVTADTLASASYGRRFTAVAGRGRCFGAQFHPERSAAVGSRLLANFLALEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFG9</accession>
    <name>A0A0S2DFG9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1714</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1714"/>
    <dbReference type="EnsemblBacteria" id="ALN57069">
        <property type="protein sequence ID" value="ALN57069"/>
        <property type="gene ID" value="GLE_1714"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1714"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1692"/>
    <dbReference type="OMA" id="IPRVRYR"/>
    <dbReference type="OrthoDB" id="433501at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="675" mass="72136" checksum="D88AA71E57C2E2C6" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFJ5</accession>
    <name>A0A0S2DFJ5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1946</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57297">
        <property type="protein sequence ID" value="ALN57297"/>
        <property type="gene ID" value="GLE_1946"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1946"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1911"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="251" mass="25071" checksum="BDDBD763BCAA6ADF" modified="2016-02-17" version="1">MDALRGDPRVVVIPACAASRVPGRAGADALDSRGMTGRDGCVIVAVISIALRSGFRMPRAASPLPTLVLLASALLAPFAAAALEPAVATPAAAEPAAAAPAAGIGATARAVSAGIVAGIRQGAQQDRNAKPAQIACARALADDAVAAPVQQVIEASLDAQDRAYLEAFYASPLGVKYQAAMLSNADPDKTFSAEEWAQAKAAMASPAYQKLRAATVSSNPLAAQKIGGVLNPLLGECFKDGDGKGGESGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFS6</accession>
    <name>A0A0S2DFS6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2052</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57402">
        <property type="protein sequence ID" value="ALN57402"/>
        <property type="gene ID" value="GLE_2052"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2052"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2017"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595073" evidence="1">
        <location>
            <begin position="21"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="201" mass="20251" checksum="9C4B37009849CF35" modified="2016-02-17" version="1">MNACSSMAIRARGWVPGALAGALLAAGLSACGERGDAPSPPAAAAPATPAASAPAFDFAAWVASNAACAGGFISDVQEAGFDKTLRDAGVGISDDASVGEVGVGSGTLTPGKPIRLHGFPVRRIEFDFGSGATFAVVVEATPEQARAAIGAKPLPQVYRDVYSEGVPMAEATEDVPMPDIRFVRKGDEPGTQEIGCAAFDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFT2</accession>
    <name>A0A0S2DFT2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_09895</name>
        <name evidence="2" type="ORF">GLE_1945</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947161.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57296">
        <property type="protein sequence ID" value="ALN57296"/>
        <property type="gene ID" value="GLE_1945"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1945"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1910"/>
    <dbReference type="OrthoDB" id="2191458at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242660" evidence="1">
        <location>
            <begin position="20"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="153" mass="16239" checksum="61D5D02F03B704EB" modified="2016-02-17" version="1">MKVFAFLAAGLLLSACASAPAVRARADASPCLPDSRQCAIYDFAMADERVLRANGEAVAVDCPWSSDEASLEQRRAHCAELIEVALAVVADRLPDALQRIPVDQVRYEDVGACVDGVARERAGGDCYRRLRAKVPLPWIVPSTGAAAAGSGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFU6</accession>
    <name>A0A0S2DFU6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-demethylubiquinone-9 3-methyltransferase domain protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">VOC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_09235</name>
        <name evidence="2" type="ORF">GLE_1798</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947056.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1798"/>
    <dbReference type="EnsemblBacteria" id="ALN57151">
        <property type="protein sequence ID" value="ALN57151"/>
        <property type="gene ID" value="GLE_1798"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1798"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1770"/>
    <dbReference type="OMA" id="RCFDSPP"/>
    <dbReference type="OrthoDB" id="1889762at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06588">
        <property type="entry name" value="PhnB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009725">
        <property type="entry name" value="3_dmu_93_MTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028973">
        <property type="entry name" value="PhnB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06983">
        <property type="entry name" value="3-dmu-9_3-mt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF021700">
        <property type="entry name" value="3_dmu_93_MTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="3-dmu-9_3-mt" evidence="1">
        <location>
            <begin position="5"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="131" mass="14447" checksum="82DF7B2F26B4D5EC" modified="2016-02-17" version="1">MPVQVCPFLMFAGRCEAAMNLYVSLIPDSRILEVRRYGPGEQGPEGSVMVASFALGDLTVMCSDSPVEHAFDFTPSSSLFVTCESREQLDVLAQALGEGGKVLMPLDNYGFSQRFAWVQDRFGVSWQLNLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFX9</accession>
    <name>A0A0S2DFX9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Protein-export membrane protein SecG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">secG</name>
        <name evidence="13" type="ORF">BV903_08595</name>
        <name evidence="14" type="ORF">FE772_10885</name>
        <name evidence="12" type="ORF">GLE_2158</name>
    </gene>
    <organism evidence="12 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">C3</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">B25</strain>
        </source>
    </reference>
    <reference evidence="14 17" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in protein export. Participates in an early event of protein translocation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the SecG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000018">
        <property type="protein sequence ID" value="OPD64354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947325.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2158"/>
    <dbReference type="EnsemblBacteria" id="ALN57508">
        <property type="protein sequence ID" value="ALN57508"/>
        <property type="gene ID" value="GLE_2158"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64354">
        <property type="protein sequence ID" value="OPD64354"/>
        <property type="gene ID" value="BV903_08595"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2158"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2121"/>
    <dbReference type="OMA" id="VIHLMIV"/>
    <dbReference type="OrthoDB" id="2082234at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004692">
        <property type="entry name" value="SecG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34182">
        <property type="entry name" value="PTHR34182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03840">
        <property type="entry name" value="SecG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01651">
        <property type="entry name" value="SECGEXPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00810">
        <property type="entry name" value="secG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0811">Translocation</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="100"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN57508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OPD64354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW26102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="171" mass="16463" checksum="D106065D6ABBB8BF" modified="2016-02-17" version="1">MLLFLNVIYVLIAIAMIALILMQRGAGAQAGSGFGGGASATVFGARGSSNFLSKSTKWLAVAFFAISLFMAWQASRTAPAQLGKPDLGVMGRVSEQSAPAAPAAAPAAAPSAIPQAPASGVPQAPAAAPSTAPANAAPAGAVPSAPAPAAAPASQPQAQPAAPAKQPANGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG18</accession>
    <name>A0A0S2DG18_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Oligoketide cyclase/lipid transport protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Type II toxin-antitoxin system RatA family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_11215</name>
        <name evidence="5" type="ORF">GLE_2225</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribosome association toxin RatA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947377.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000078.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2225"/>
    <dbReference type="EnsemblBacteria" id="ALN57574">
        <property type="protein sequence ID" value="ALN57574"/>
        <property type="gene ID" value="GLE_2225"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2225"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2190"/>
    <dbReference type="OMA" id="YSVEQMF"/>
    <dbReference type="OrthoDB" id="1691158at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048039">
        <property type="term" value="F:ubiquinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045333">
        <property type="term" value="P:cellular respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07813">
        <property type="entry name" value="COQ10p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044996">
        <property type="entry name" value="COQ10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005031">
        <property type="entry name" value="COQ10_START"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12901">
        <property type="entry name" value="PTHR12901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03364">
        <property type="entry name" value="Polyketide_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-1277">Toxin-antitoxin system</keyword>
    <feature type="domain" description="Polyketide_cyc" evidence="4">
        <location>
            <begin position="10"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW26154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="162" mass="17592" checksum="0DD2176692674CE6" modified="2016-02-17" version="1">MPTIRRSALVEHSAARMFALVNDVAAYPRRFDWCEAAQILEADATHMVARLDLGLGALRTWFTTHNALSPPHHIELKLVDGPFRKLGGRWEFHALDESACKVTLTLEFEPAVKLLGPAMALGFQSLADRMVDDFVRVADRGAEPAPPAEVAAPAPDAGNAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGI9</accession>
    <name>A0A0S2DGI9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB-dependent siderophore receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLE_2417</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2417"/>
    <dbReference type="EnsemblBacteria" id="ALN57766">
        <property type="protein sequence ID" value="ALN57766"/>
        <property type="gene ID" value="GLE_2417"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2417"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2379"/>
    <dbReference type="OMA" id="VETEYHY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015344">
        <property type="term" value="F:siderophore uptake transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010105">
        <property type="entry name" value="TonB_sidphr_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01783">
        <property type="entry name" value="TonB-siderophor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595002" evidence="7">
        <location>
            <begin position="32"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="68"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="245"/>
            <end position="736"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN57766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="738" mass="80343" checksum="368AAE771D17EF1D" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGL5</accession>
    <name>A0A0S2DGL5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AraC family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BV903_02135</name>
        <name evidence="6" type="ORF">FE772_11855</name>
        <name evidence="4" type="ORF">GLE_2368</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">C3</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000004">
        <property type="protein sequence ID" value="OPD65585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947485.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2368"/>
    <dbReference type="EnsemblBacteria" id="ALN57717">
        <property type="protein sequence ID" value="ALN57717"/>
        <property type="gene ID" value="GLE_2368"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65585">
        <property type="protein sequence ID" value="OPD65585"/>
        <property type="gene ID" value="BV903_02135"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2368"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2329"/>
    <dbReference type="OMA" id="TWRQQAC"/>
    <dbReference type="OrthoDB" id="1757088at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003313">
        <property type="entry name" value="AraC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02311">
        <property type="entry name" value="AraC_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="3">
        <location>
            <begin position="157"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD65585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW26260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="265" mass="29135" checksum="4E0409008986D048" modified="2016-02-17" version="1">MRNVLAGQADQLPGRIVATSNEYPTGHRIARHSHRRSQLLYGAHGIMVVGTQAGRWMVPPERAAWIPAGMAHDVHVLAQISTRSIYVEPEVSAALPGDCRVIGVSALMRELLLETLDLPLQADAAGGSRPDLIYSLIVREIERAPVLPLDIPFPSEPRLAARCRAYLAQPSPHDGIDDWCRDLAMSRRTFTRRFRAQTGSSFAQWCRQAAIFAALPRLAAGEPITALALDLGYESASAFTTMFKRLIGMPPSRYLATARAYAPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGQ9</accession>
    <name>A0A0S2DGQ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2416</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57765">
        <property type="protein sequence ID" value="ALN57765"/>
        <property type="gene ID" value="GLE_2416"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2416"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2378"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="45" mass="5306" checksum="F6F2A02EC6AEBC9F" modified="2016-02-17" version="1">MRTDRNSGRAPGCAEARRNRRNRRRRAFARAGRESPPRRGFLLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGW7</accession>
    <name>A0A0S2DGW7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Luciferase-like monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2519</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57868">
        <property type="protein sequence ID" value="ALN57868"/>
        <property type="gene ID" value="GLE_2519"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2519"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2482"/>
    <dbReference type="OMA" id="ERHFHRF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024011">
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    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04020">
        <property type="entry name" value="seco_metab_LLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="1">
        <location>
            <begin position="34"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="366" mass="39969" checksum="9EA15366B89ACAA6" modified="2016-02-17" version="1">MPALPPVPAALAAPRRRRQRERPARMKISLFFFGADSDQADKYRLLFDAVRFADAHGLYAAWVPERHFLRFGGLYGNPSVTAAAIAAMTSRLQIRAGSVVMPLHHPLEVAEAWSMIDHFSNGRAGIAIASGWHVNDFVLAPERYAQRGPIMLDSIELVQRLWRGESVEFANGEGVATPTAILPRPLRPDIPVWMTASSEDGCALAGERGFGLLTSNFGNNYSLDVLGRKVARYRAGARPGAQLTLMLHAYVGASAQDVAAHALPAMMEYLHSNIAMQASQDAGRGEDRGYAELQGRRERKFLQLRAAANINSELSFVGTVEDCVRRARTLQAAGVDEIACLIDFGIAYDATMAGLQRLAEVARRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH22</accession>
    <name>A0A0S2DH22_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TetR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">TetR/AcrR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_01480</name>
        <name evidence="5" type="ORF">FE772_12410</name>
        <name evidence="3" type="ORF">GLE_2484</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000003">
        <property type="protein sequence ID" value="OPD65695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947573.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2484"/>
    <dbReference type="EnsemblBacteria" id="ALN57833">
        <property type="protein sequence ID" value="ALN57833"/>
        <property type="gene ID" value="GLE_2484"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65695">
        <property type="protein sequence ID" value="OPD65695"/>
        <property type="gene ID" value="BV903_01480"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2484"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2446"/>
    <dbReference type="OMA" id="KSFAFWP"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039536">
        <property type="entry name" value="TetR_C_Proteobacteria"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14246">
        <property type="entry name" value="TetR_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="11"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD65695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="205" mass="22813" checksum="9E961A8334951303" modified="2016-02-17" version="1">MPTPAPARLTDRKRAAILDAAIAEFRQAGYEATSMDRVAASAGVSKRTVYNHFPSKEVLFAHILRQLMERTLASPELAYRADRPLRAQLLELVRQKMELLQDESFIDLARAGIASVIPSPERAQQMFGRIGDKEEGLVVWIRAAAADGRLNTDDPGFASTFMFGMIKGFAFWPQITMGQPLLTEEQRDRVAQTATDMFLAHFATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH24</accession>
    <name>A0A0S2DH24_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Group III truncated hemoglobin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_11990</name>
        <name evidence="2" type="ORF">GLE_2395</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947509.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57744">
        <property type="protein sequence ID" value="ALN57744"/>
        <property type="gene ID" value="GLE_2395"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2395"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2357"/>
    <dbReference type="OMA" id="RIAWAMH"/>
    <dbReference type="OrthoDB" id="1697277at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001486">
        <property type="entry name" value="Hemoglobin_trunc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01152">
        <property type="entry name" value="Bac_globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="122" mass="13809" checksum="82DCDCF0D6E04314" modified="2016-02-17" version="1">MRSFEGLDEAALTALVRRFYVAVRADAELGPVFAAAVRDWDEHERRLIDFWTSSMLGSGRYRGNPAQSHLDHASRIRPELFARWLALWRRCSEEVLPPAQAAAVQERAARIGGHLQRLLAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH87</accession>
    <name>A0A0S2DH87_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cellulase</fullName>
            <ecNumber evidence="5">3.2.1.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_2459</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.4" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947553.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2459"/>
    <dbReference type="EnsemblBacteria" id="ALN57808">
        <property type="protein sequence ID" value="ALN57808"/>
        <property type="gene ID" value="GLE_2459"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2459"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2421"/>
    <dbReference type="OMA" id="THQGAEW"/>
    <dbReference type="OrthoDB" id="1395441at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cellulase" evidence="4">
        <location>
            <begin position="43"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="371"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="397" mass="43905" checksum="2C1FB855F7507412" modified="2016-02-17" version="1">MRARRRRGLALGAGLALWLLACAAVEAMPLRRGVALSRWFEASAGAPVSAAELRALRAAGFDHVRIPVDPVSLGWSPRRGPKLDDARLRAAIDAALAAGLDAIVDLHPREQTKQAIERGGEWADGYVALWKALAADWKTLPTQRVAFELFNEPGFYGWTGGLAWSRYQQRLVAAVRGVDRERVLIVSGRKGGSLEGLVELAPLDDDKLIYSFHYYLPYVFTHQGASWMRGDEWTTAGHWRSVRYPAKAAQARLPHTDGGVGRDRARDEIADYFRDGWDRERIAAQWRPLREWAGKHKVRVHCGEFGTIREGVDPDSRYRWIGDVRALAEAEGWGWSVWNYADDFGLTANSNTTGAPRGALEPAALRALGLDARGRGSPAATRTRGQSSPPEPRQGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHC5</accession>
    <name>A0A0S2DHC5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2614</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57962">
        <property type="protein sequence ID" value="ALN57962"/>
        <property type="gene ID" value="GLE_2614"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2614"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2574"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="45" mass="5236" checksum="C98D7E5B00FE1A2A" modified="2016-02-17" version="1">MPVQIDLSTEDFEQLQQEVIGEPDLCDDKMETARVPWTPRWTCIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHH1</accession>
    <name>A0A0S2DHH1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Exodeoxyribonuclease I</fullName>
            <ecNumber evidence="2 12">3.1.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">sbcB</name>
        <name evidence="18" type="ORF">FE772_13425</name>
        <name evidence="17" type="ORF">GLE_2680</name>
    </gene>
    <organism evidence="17 19">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="17 19" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">C3</strain>
        </source>
    </reference>
    <reference evidence="18 20" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 20">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="14">Binds 2 Mg(2+) ions per monomer.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.1" evidence="2 12"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947730.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2680"/>
    <dbReference type="EnsemblBacteria" id="ALN58028">
        <property type="protein sequence ID" value="ALN58028"/>
        <property type="gene ID" value="GLE_2680"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2680"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2639"/>
    <dbReference type="OMA" id="RDRPAQF"/>
    <dbReference type="OrthoDB" id="768812at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-exoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008852">
        <property type="term" value="F:exodeoxyribonuclease I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.20">
        <property type="match status" value="1"/>
    </dbReference>
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        <citation type="journal article" date="2016" name="DNA Res." volume="0" first="0" last="0">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer, Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M497-1</strain>
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        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">ATCC 29487</strain>
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    <reference evidence="9 17" key="4">
        <citation type="journal article" date="2017" name="DNA Res." volume="24" first="169" last="177">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
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            <dbReference type="DOI" id=".1093/dnares/dsw055"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 17">M497-1</strain>
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        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10 16">B25</strain>
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        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 18">OH11</strain>
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    <reference evidence="11 19" key="7">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 19">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6 7">Belongs to the bacterial ribosomal protein bS18 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP014940">
        <property type="protein sequence ID" value="BAV97876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000052">
        <property type="protein sequence ID" value="OPD62382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000037">
        <property type="protein sequence ID" value="ROU06066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNOG01000006">
        <property type="protein sequence ID" value="SDX64201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_031372470.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000037.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2649"/>
    <dbReference type="EnsemblBacteria" id="ALN57997">
        <property type="protein sequence ID" value="ALN57997"/>
        <property type="gene ID" value="GLE_2649"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAV97876">
        <property type="protein sequence ID" value="BAV97876"/>
        <property type="gene ID" value="LEN_2389"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62382">
        <property type="protein sequence ID" value="OPD62382"/>
        <property type="gene ID" value="BV903_18675"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDX64201">
        <property type="protein sequence ID" value="SDX64201"/>
        <property type="gene ID" value="SAMN05421681_106363"/>
    </dbReference>
    <dbReference type="KEGG" id="lem:LEN_2389"/>
    <dbReference type="KEGG" id="lez:GLE_2649"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2608"/>
    <dbReference type="OMA" id="QKKYCRF"/>
    <dbReference type="OrthoDB" id="1940575at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000183696">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000218824">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00270">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001648">
        <property type="entry name" value="Ribosomal_S18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018275">
        <property type="entry name" value="Ribosomal_S18_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036870">
        <property type="entry name" value="Ribosomal_S18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479">
        <property type="entry name" value="PTHR13479"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01084">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00974">
        <property type="entry name" value="RIBOSOMALS18"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46911">
        <property type="entry name" value="SSF46911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00165">
        <property type="entry name" value="S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00057">
        <property type="entry name" value="RIBOSOMAL_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN57997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAV97876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD62382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW26491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROU06066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDX64201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000183696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000218824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="76" mass="8917" checksum="6C4A0988B548A4C4" modified="2016-02-17" version="1">MSKFFRRRKFCKFTAEGVKEIDYKDLNTLRQYLTETGKIVPSRVTGTKSKYQRQLATAVKRARFLALIPYTDNHNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIA2</accession>
    <name>A0A0S2DIA2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Oligoribonuclease</fullName>
            <ecNumber evidence="3">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">orn</name>
        <name evidence="5" type="ORF">GLE_2879</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">3'-to-5' exoribonuclease specific for small oligoribonucleotides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the oligoribonuclease family.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2879"/>
    <dbReference type="EnsemblBacteria" id="ALN58227">
        <property type="protein sequence ID" value="ALN58227"/>
        <property type="gene ID" value="GLE_2879"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2879"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2841"/>
    <dbReference type="OMA" id="AFFHYRN"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-exoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06135">
        <property type="entry name" value="Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00045">
        <property type="entry name" value="Oligoribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022894">
        <property type="entry name" value="Oligoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11046">
        <property type="entry name" value="PTHR11046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="4">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="179" mass="20403" checksum="36A825586B252E8F" modified="2016-02-17" version="1">MIWIDLEMTGLDTDRDSILEIATVVTDAQLNVLAEGPELAIAHPLQRLEAMDEWNRNQHGKSGLWQRVLEQGVAMEEAERQTLEFLARWVAPNTSPICGNSICQDRRFLHRCMPKLEKYFHYRNLDVSTVKELARRWAPEVLAGMHKDSKHTALSDVHDSIAELRHYRGFMGKLGGLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIN3</accession>
    <name>A0A0S2DIN3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3047</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SDHAF4 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3047"/>
    <dbReference type="EnsemblBacteria" id="ALN58394">
        <property type="protein sequence ID" value="ALN58394"/>
        <property type="gene ID" value="GLE_3047"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3047"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3007"/>
    <dbReference type="OMA" id="WTVKGRC"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012875">
        <property type="entry name" value="SDHF4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07896">
        <property type="entry name" value="DUF1674"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="54" mass="5602" checksum="EBB51325E886FCEF" modified="2016-02-17" version="1">MSGAAETGGASPSAKDALVEAAAQAQPPKEHGGRDGLEPTRYGDWEKNGRCIDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIQ9</accession>
    <name>A0A0S2DIQ9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase</fullName>
            <ecNumber evidence="3">2.7.6.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">folK</name>
        <name evidence="14" type="ORF">GLE_3177</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HPPK family.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.3" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948099.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3177"/>
    <dbReference type="EnsemblBacteria" id="ALN58523">
        <property type="protein sequence ID" value="ALN58523"/>
        <property type="gene ID" value="GLE_3177"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3177"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3132"/>
    <dbReference type="OMA" id="QVILRQN"/>
    <dbReference type="OrthoDB" id="1953248at2"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003848">
        <property type="term" value="F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00483">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000550">
        <property type="entry name" value="Hppk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035907">
        <property type="entry name" value="Hppk_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01288">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55083">
        <property type="entry name" value="SSF55083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01498">
        <property type="entry name" value="folK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00794">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="7 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HPPK" evidence="13">
        <location>
            <begin position="95"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS00794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN58523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="171" mass="18122" checksum="5C52B8898F3D32D5" modified="2016-02-17" version="1">MTPTVSAYIGLGSNLGDSAAVLRAAVDALAALPHSRLRRASRLYRTAAWGRTDQPDFLNAVAWLDTALPARELLAAMLGIEREAGRARRADGSDRWGPRTLDLDLLLYGEAVIAETGLQVPHPHLHERAFALAPLVEIAPQASIPGVGPAHEALARIELGGIEVLDEGEGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIV2</accession>
    <name>A0A0S2DIV2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Lipoprotein releasing system, transmembrane protein, LolC/E family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="12">Lipoprotein-releasing ABC transporter permease subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FE772_15190</name>
        <name evidence="11" type="ORF">GLE_3039</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947998.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3039"/>
    <dbReference type="EnsemblBacteria" id="ALN58386">
        <property type="protein sequence ID" value="ALN58386"/>
        <property type="gene ID" value="GLE_3039"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3039"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2999"/>
    <dbReference type="OMA" id="GWWQQNG"/>
    <dbReference type="OrthoDB" id="768211at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042953">
        <property type="term" value="P:lipoprotein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011925">
        <property type="entry name" value="LolCE_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02212">
        <property type="entry name" value="lolCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="22"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="270"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="318"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="10">
        <location>
            <begin position="27"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="9">
        <location>
            <begin position="301"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN58386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW26786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="414" mass="44698" checksum="B166F94EFA36058B" modified="2016-02-17" version="1">MFKPISVAIGLRYLRAKRRNGFISFISLASIAGIALGVTALITTLAVMSGFQREIRDRMLQMAAHATVSAYGEPLQDWRHAVEMATADQRVAGAAPYVEKEALLSAARQQPAIVRGVDPALEGRVSVLADKMVQGKLDSLTPGSFNIVLGKELALWMGAQVGDSVVVMTADGRSTPMGAMPQLKRFTVSGVFEAGYNEYDKGLAVANMQDMQRVLRMGEGVTGVRLKLHDMDQAWDVARDLAVNLGGPYRVTDWSSDNANMFRALKMEKTVMAILLSLIIAMGAFNLVSSQVMLVTDKQADIAIQRTLGLTPMSVMRIFVVQGTLIGIIGTVLGVIGGIVLTLNLEHILKAIEAVLGVQLLPEDVYYITGLPTDLRTSDVTVIACVALAMAFLATIYPAWRAARTAPAEALRYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ94</accession>
    <name>A0A0S2DJ94_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase</fullName>
            <ecNumber evidence="3">2.7.6.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">BV903_14375</name>
        <name evidence="14" type="ORF">GLE_3012</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">C3</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">B25</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HPPK family.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.3" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000037">
        <property type="protein sequence ID" value="OPD63177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947979.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000037.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58360">
        <property type="protein sequence ID" value="ALN58360"/>
        <property type="gene ID" value="GLE_3012"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63177">
        <property type="protein sequence ID" value="OPD63177"/>
        <property type="gene ID" value="BV903_14375"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3012"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2973"/>
    <dbReference type="OrthoDB" id="1831387at2"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003848">
        <property type="term" value="F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000550">
        <property type="entry name" value="Hppk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035907">
        <property type="entry name" value="Hppk_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01288">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55083">
        <property type="entry name" value="SSF55083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="7 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HPPK" evidence="13">
        <location>
            <begin position="7"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN58360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OPD63177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="186" mass="20442" checksum="2024C8F26136BC11" modified="2016-02-17" version="1">MSATALICLGASDGPRAENLLEAGAQLLAEPGTSLAAVSGLYGDRHYLHTGDATLNLVLALDWRDPPQPQALERRFKRIEAGFGRQRDPRRRMPVPLDIDLLGALDADGPRWQPRYDPGRGYLFHGLSQLPLAPLQAALDALQRQRGFRGEDNAHGFYAYAGVGFVRRYLIERAAQLRDAGQREAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJB6</accession>
    <name>A0A0S2DJB6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Ribonuclease</fullName>
            <ecNumber evidence="12">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLE_3385</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 12">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the RNase HII family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="12"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3385"/>
    <dbReference type="EnsemblBacteria" id="ALN58731">
        <property type="protein sequence ID" value="ALN58731"/>
        <property type="gene ID" value="GLE_3385"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3385"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3335"/>
    <dbReference type="OMA" id="YPTKLHL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07182">
        <property type="entry name" value="RNase_HII_bacteria_HII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022898">
        <property type="entry name" value="RNase_HII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001352">
        <property type="entry name" value="RNase_HII/HIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024567">
        <property type="entry name" value="RNase_HII/HIII_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954">
        <property type="entry name" value="PTHR10954"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954:SF18">
        <property type="entry name" value="PTHR10954:SF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01351">
        <property type="entry name" value="RNase_HII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 12" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="10 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 12" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase_HII" evidence="13">
        <location>
            <begin position="2"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN58731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="173" mass="19493" checksum="C902A746DAEAD827" modified="2016-02-17" version="1">MAAVILNPRRRIDGLDDSKKLSERKRDALFPLIQERALAWRIEFVEVEEIDRINIFQATMAGMRRALLALAPQAELARVDGNHLPRDLPCRGEALVGGDALEPAIMAASILAKVARDRLMAQVHQDWPQYGFDRHKGYSTAAHLAALRAHGPCPQHRRSFAPVRIETEQRSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJB9</accession>
    <name>A0A0S2DJB9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3146</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58493">
        <property type="protein sequence ID" value="ALN58493"/>
        <property type="gene ID" value="GLE_3146"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3146"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="108" mass="11317" checksum="25FBA80454828B3A" modified="2016-02-17" version="1">MEHGAVRGPDFLSAGLMLAALAGAALLQLGCICCGALAANPSVRNFGERRNPFWLCCCLLLLLLQRATTSQDQGLPSASGRVTFFVLSHKESNGGVNVQVHHPAPAGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJK9</accession>
    <name>A0A0S2DJK9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">Catalase-peroxidase</fullName>
            <shortName evidence="8">CP</shortName>
            <ecNumber evidence="8 9">1.11.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Peroxidase/catalase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">katG</name>
        <name evidence="12" type="ORF">FE772_16085</name>
        <name evidence="11" type="ORF">GLE_3243</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 9">
            <text>2 H2O2 = 2 H2O + O2</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.21"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>AH2 + H2O2 = A + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:30275"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="EC" id="1.11.1.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="8">Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer or homotetramer.</text>
    </comment>
    <comment type="PTM">
        <text evidence="8">Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the peroxidase family. Peroxidase/catalase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.21" evidence="8 9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948149.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3243"/>
    <dbReference type="EnsemblBacteria" id="ALN58589">
        <property type="protein sequence ID" value="ALN58589"/>
        <property type="gene ID" value="GLE_3243"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3243"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3196"/>
    <dbReference type="OMA" id="MILAGNC"/>
    <dbReference type="OrthoDB" id="49441at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01961">
        <property type="entry name" value="Catal_peroxid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000763">
        <property type="entry name" value="Catalase_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30555">
        <property type="entry name" value="PTHR30555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00460">
        <property type="entry name" value="BPEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 8 9" id="KW-0575">Peroxidase</keyword>
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            <begin position="125"/>
            <end position="420"/>
        </location>
    </feature>
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            <position position="92"/>
        </location>
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    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="255"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
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            <position position="88"/>
        </location>
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    <feature type="cross-link" description="Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-91)" evidence="8">
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            <end position="240"/>
        </location>
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    </evidence>
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            <dbReference type="HAMAP-Rule" id="MF_01961"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU003451"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN58589.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW26928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="726" mass="78685" checksum="67DE61CAFEF57DDF" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJQ3</accession>
    <name>A0A0S2DJQ3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-dependent Clp protease ATP-binding subunit ClpX</fullName>
        </recommendedName>
    </protein>
    <gene>
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        <name evidence="10" type="ORF">BV903_17940</name>
        <name evidence="12" type="ORF">D9T17_11160</name>
        <name evidence="11" type="ORF">FE772_16865</name>
        <name evidence="9" type="ORF">GLE_3418</name>
    </gene>
    <organism evidence="9 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="10 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="11 16" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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        <text evidence="6">ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.</text>
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    <comment type="subunit">
        <text evidence="6">Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the ClpX chaperone family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ALN58764">
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    </dbReference>
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    <dbReference type="OMA" id="HYKRVQA"/>
    <dbReference type="OrthoDB" id="718259at2"/>
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    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="project" value="InterPro"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="InterPro" id="IPR010603">
        <property type="entry name" value="Znf_CppX_C4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038366">
        <property type="entry name" value="Znf_CppX_C4_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06689">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00994">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="clpX"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CLPX_ZB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6 7" id="KW-0143">Chaperone</keyword>
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    <keyword evidence="1 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ClpX-type ZB" evidence="8">
        <location>
            <begin position="7"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="123"/>
            <end position="130"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01250"/>
        </source>
    </evidence>
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            <dbReference type="PROSITE" id="PS51902"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="ALN58764.1"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="OPD62549.1"/>
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    </evidence>
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            <dbReference type="EMBL" id="QCW27061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROU07058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
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            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="431" mass="47764" checksum="BA795F4EDB1A90EA" modified="2016-02-17" version="1">MTDERQGRSTGDSNKILYCSFCGKSQHEVRKLIAGPSVFICDECVELCNDIIREELEEKAQSARSHLPKPREILEVLDQYVIGQQRAKRTLAVAVYNHYKRIESRQKNDDVELSKSNILLVGPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQQGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIASVPPQGGRKHPQQEFLQVDTRNILFVVGGAFAGLDKIIQQRSTEAGGIGFGAKVKSAERKIDIGKILADVEPEDLIKFGLIPEFVGRLPVVATLEELDEPALISILTEPKNAITKQFRKLFEMENVELEFRPDALSAIAKKALKRKTGARGLRTIVESVLLDTMYELPSLENVSKVVVDESVIEHKSEPYLIYQTPPAQQQPKVASAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK67</accession>
    <name>A0A0S2DK67_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">HNH endonuclease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">HNH endonuclease domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">D9T17_10365</name>
        <name evidence="4" type="ORF">FE772_17495</name>
        <name evidence="3" type="ORF">GLE_3554</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000023">
        <property type="protein sequence ID" value="ROU07345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3554"/>
    <dbReference type="EnsemblBacteria" id="ALN58898">
        <property type="protein sequence ID" value="ALN58898"/>
        <property type="gene ID" value="GLE_3554"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3554"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3498"/>
    <dbReference type="OMA" id="GMPLEWI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029471">
        <property type="entry name" value="HNH_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14279">
        <property type="entry name" value="HNH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00507">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNHc" evidence="2">
        <location>
            <begin position="112"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU07345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="219" mass="24297" checksum="0750D22125E7777D" modified="2016-02-17" version="1">MLQREPEVSGVGEPYSPWTGPRAVPRNPLERLNSVRLLSLDAHGRVLDWMNWQDAACLYARGAVAWTLGDPCLQVHGGINRFTGERSVLELHPIVAARGHARPGALDPTPALTNAALFARDGHLCMYCGHDFHRPHLTRDHVVPVSKGGRDIWENVVAACFGCNSRKGNRTPQQAGMPLLAVPYRPSWVEHLILSNRNILADQMAFLKNQLPKNSRRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK92</accession>
    <name>A0A0S2DK92_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LPS-assembly lipoprotein LptE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rlpB</name>
        <name evidence="2" type="synonym">lptE</name>
        <name evidence="3" type="ORF">GLE_3436</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LptE lipoprotein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3436"/>
    <dbReference type="EnsemblBacteria" id="ALN58781">
        <property type="protein sequence ID" value="ALN58781"/>
        <property type="gene ID" value="GLE_3436"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3436"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3386"/>
    <dbReference type="OMA" id="TTVNRNY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01186">
        <property type="entry name" value="LPS_assembly_LptE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007485">
        <property type="entry name" value="LPS_assembly_LptE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38098">
        <property type="entry name" value="PTHR38098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04390">
        <property type="entry name" value="LptE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="160" mass="17598" checksum="CF01D31252A131E3" modified="2016-02-17" version="1">MLALSACGFQLRQALTLPPDLGPVRVVSVDRYSPLAESLAQALTRAGAVPAQDGSTEVAVLDLMSERWGDTPAALDELGRVQEYSLRYAVVFELRKSDGKPLVPRQSIELSRDYVSNPTNAIGTEGEREILMREMRREMSSAVLRRIGAVTERGAVVERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKC4</accession>
    <name>A0A0S2DKC4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="12">DEAD/DEAH box helicase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="11">DEAD/DEAH box helicase/helicase conserved C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FE772_17090</name>
        <name evidence="11" type="ORF">GLE_3468</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948314.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3468"/>
    <dbReference type="EnsemblBacteria" id="ALN58813">
        <property type="protein sequence ID" value="ALN58813"/>
        <property type="gene ID" value="GLE_3468"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3468"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3415"/>
    <dbReference type="OMA" id="KKKTHDM"/>
    <dbReference type="OrthoDB" id="643629at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="10">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="32"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="234"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="377"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="406"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="432"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN58813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW27095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="448" mass="47957" checksum="C6316047E8EE3664" modified="2016-02-17" version="1">MTFESLGLAPALLRALSEQNYATPTPIQAEAIPLAMAGHDLLGGAQTGTGKTAAFGLPLLHRLATAAPQGGPRKPRALILAPTRELALQVSDSLRGYAKYLRLNVHAIYGGAGMGPQLDALRRGVDVLVATPGRLIDHLERGSAKLDAVELLVMDEADRMLDMGFLPAIKRILGRLPASRQTLLFSATFEAQIKQLALEFMRTPQQVQIAAKNVVADAISHRVHPVDGGRKRDLLIQILAARPNDQVIVFGRTKHGCNRLAEQLEDAGLKAVAIHGNKSQAQRQKALRDFKANKARVLVATDVAARGLDIPSLPLVINFDLPMVAEDYVHRIGRTGRNGATGEALSLVSPDEAGLLRQIQRILKDDIEMVSVAGFEPSRPLRMGSDAPGARRPGPGGNNRGNNAPRKPAHRPHGKPAPRHAHAGPKQHRGGNGGGGQQQGQRRDRSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKM8</accession>
    <name>A0A0S2DKM8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Protein translocase subunit SecY</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 13" type="primary">secY</name>
        <name evidence="15" type="ORF">D9T17_09530</name>
        <name evidence="14" type="ORF">FE772_18550</name>
        <name evidence="13" type="ORF">GLE_3770</name>
    </gene>
    <organism evidence="13 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">C3</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">OH11</strain>
        </source>
    </reference>
    <reference evidence="14 18" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 18">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 11">Membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 12">Belongs to the SecY/SEC61-alpha family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000023">
        <property type="protein sequence ID" value="ROU07201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948537.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3770"/>
    <dbReference type="EnsemblBacteria" id="ALN59114">
        <property type="protein sequence ID" value="ALN59114"/>
        <property type="gene ID" value="GLE_3770"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3770"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3714"/>
    <dbReference type="OMA" id="FAMWLGE"/>
    <dbReference type="OrthoDB" id="1567535at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01465">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026593">
        <property type="entry name" value="SecY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002208">
        <property type="entry name" value="SecY/SEC61-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030659">
        <property type="entry name" value="SecY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023201">
        <property type="entry name" value="SecY_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10906">
        <property type="entry name" value="PTHR10906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00344">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004557">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103491">
        <property type="entry name" value="SSF103491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00967">
        <property type="entry name" value="3a0501s007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00755">
        <property type="entry name" value="SECY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00756">
        <property type="entry name" value="SECY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 11" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="377"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="405"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN59114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW27342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ROU07201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="457" mass="49019" checksum="3792B5DEBD0F635F" modified="2016-02-17" version="1">MARSGNAMAGIGGGLGKFTELRQRLLFVIGALIVYRIGSYIPVPGINPEAMVKFMETKQGTIVDMFNMFTGGALHRFSLFALNVMPYISASIIVQLLVQIVPSLKAIQKEGESGRRKINQWSRMGAIPLAVFQAWGIAAGLQSSVAPDGVPVVYAPGMGFILTAVIALTAGTMFLMWLGEQITERGVGNGVSLIIFAGIVAGLPAAVLHMFEQIRNGDMSAIAAIVVILLVFGFTYLVVFVERGQRRITVNYARRQGGRNAYMNQASFLPLKLNMSGVIPAIFASSIVMFPATAATWFAQSNSGSGFSGFLQRLSQWLAPGEPVHMILYAGLIIGFAFFYTALVFNSQETADNLKKSGALIPGIRPGKATADYVDGVLTRLTAAGAIYLVIVCLLPEVMRTQLGTSFYFGGTSLLIVVVVVMDFIAQIQAHLMSHQYESLLKKANLKGGSRGGLARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKN6</accession>
    <name>A0A0S2DKN6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Coenzyme PQQ synthesis protein B</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Pyrroloquinoline quinone biosynthesis protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">pqqB</name>
        <name evidence="9" type="ORF">GLE_3756</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in the transport of PQQ or its precursor to the periplasm.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the PqqB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3756"/>
    <dbReference type="EnsemblBacteria" id="ALN59100">
        <property type="protein sequence ID" value="ALN59100"/>
        <property type="gene ID" value="GLE_3756"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3756"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3700"/>
    <dbReference type="OMA" id="FYIPGCA"/>
    <dbReference type="UniPathway" id="UPA00539"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018189">
        <property type="term" value="P:pyrroloquinoline quinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16274">
        <property type="entry name" value="PQQB-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00653">
        <property type="entry name" value="PQQ_syn_PqqB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011842">
        <property type="entry name" value="PQQ_synth_PqqB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02108">
        <property type="entry name" value="PQQ_syn_pqqB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0884">PQQ biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Lactamase_B" evidence="8">
        <location>
            <begin position="51"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN59100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="310" mass="33827" checksum="AE9FEDBF89A3754B" modified="2016-02-17" version="1">MMRILVLGAAAGGGYPQWNCNTPGSRRAWRGEDGAKRRSQASIAVSADGERWLLVNASPDFRQQVLALPPLWPRHGLRHSPIEAVLLSSGEIDHIAGLLSMRERQRFDLWASARVHALLAQNPIFDALHPDYVTRKPLALDTPTDIVGLDSLLGLRVTAFSVPGKVPLFMESRSPDLRGGDEETLGLEITDGRERFYYIPGCAALTQSLRERLRGAALVFFDGTLWRDDEMQRAGVGGKTGARMGHMSIAGGNGADDAGTLAAFAGLDVRRKLFIHLNTTNPVLDEASPERAQVRAQGWEVAEDGMELTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKP2</accession>
    <name>A0A0S2DKP2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase, families S8 and S53/proprotein convertase P-domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_3847</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3847"/>
    <dbReference type="EnsemblBacteria" id="ALN59190">
        <property type="protein sequence ID" value="ALN59190"/>
        <property type="gene ID" value="GLE_3847"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3847"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3787"/>
    <dbReference type="OMA" id="HPAQGIL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002884">
        <property type="entry name" value="P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01483">
        <property type="entry name" value="P_proprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51829">
        <property type="entry name" value="P_HOMO_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="P/Homo B" evidence="7">
        <location>
            <begin position="531"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="249"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="653" mass="65599" checksum="42FA62AAFED4C0C1" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKV9</accession>
    <name>A0A0S2DKV9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5 7">30S ribosomal protein S12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">rpsL</name>
        <name evidence="10" type="ORF">BV903_21065</name>
        <name evidence="12" type="ORF">D9T17_09405</name>
        <name evidence="11" type="ORF">FE772_18675</name>
        <name evidence="9" type="ORF">GLE_3795</name>
    </gene>
    <organism evidence="9 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 13">C3</strain>
        </source>
    </reference>
    <reference evidence="10 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">OH11</strain>
        </source>
    </reference>
    <reference evidence="11 16" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 16">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5 7">Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="1 5 7">With S4 and S5 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 7">Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 6">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000067">
        <property type="protein sequence ID" value="OPD61932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000023">
        <property type="protein sequence ID" value="ROU07178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948559.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3795"/>
    <dbReference type="EnsemblBacteria" id="ALN59139">
        <property type="protein sequence ID" value="ALN59139"/>
        <property type="gene ID" value="GLE_3795"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61932">
        <property type="protein sequence ID" value="OPD61932"/>
        <property type="gene ID" value="BV903_21065"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3795"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3739"/>
    <dbReference type="OMA" id="SPALEKC"/>
    <dbReference type="OrthoDB" id="1707228at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03368">
        <property type="entry name" value="Ribosomal_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00403_B">
        <property type="entry name" value="Ribosomal_S12_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_S12/S23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005679">
        <property type="entry name" value="Ribosomal_S12_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="PTHR11652"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01034">
        <property type="entry name" value="RIBOSOMALS12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00981">
        <property type="entry name" value="rpsL_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 6 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN59139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD61932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW27366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROU07178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="124" mass="13658" checksum="FD989A94930E08E3" modified="2016-02-17" version="1">MATINQLVRKPRQAATYKSTSPALANCPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTNGYEVISYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGSLDAAGVAKRRQSRSKYGAKRPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL58</accession>
    <name>A0A0S2DL58_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Peptidase, families S8 and S53/PKD domain/proprotein convertase P-domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLE_3850</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3850"/>
    <dbReference type="EnsemblBacteria" id="ALN59193">
        <property type="protein sequence ID" value="ALN59193"/>
        <property type="gene ID" value="GLE_3850"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3850"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3790"/>
    <dbReference type="OMA" id="AYSANAM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002884">
        <property type="entry name" value="P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01483">
        <property type="entry name" value="P_proprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51829">
        <property type="entry name" value="P_HOMO_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595200" evidence="7">
        <location>
            <begin position="32"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="8">
        <location>
            <begin position="486"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="P/Homo B" evidence="9">
        <location>
            <begin position="565"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="210"/>
            <end position="240"/>
        </location>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51829"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN59193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="686" mass="68356" checksum="3CE4792AE23AC200" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL60</accession>
    <name>A0A0S2DL60_LYSEN</name>
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    </gene>
    <organism evidence="2 3">
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="24"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="287" mass="32963" checksum="1D8A191263C82CBD" modified="2016-02-17" version="1">MRHLTTQIDGTDIFYREAGPADAPVLLLPHGYPCSSFQYRNLMPALGDRWRTLAPDFPGFGYSGTPDPQGFGYDFDAYADFLAKFADRLRLKRYALWLHDYGSQIGLRHAIAHPQRIAALIVQNGDIYEDALGPKYATIKRYWADRSPRNRAPLEEAVSEQGFRDEFVGEVSEEVASRVAPDLWKLHWPLMDTPVRREAMVGLMDKLEANLDWFPRYQRYLREQRPPALIVWGPRDGYMPAAAARAYLRDLPDAELHLLDGAGHWLLETHFDQALPRVREFLQRAHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLE8</accession>
    <name>A0A0S2DLE8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">rpsJ</name>
        <name evidence="8" type="ORF">BV903_23040</name>
        <name evidence="10" type="ORF">D9T17_09425</name>
        <name evidence="9" type="ORF">FE772_18655</name>
        <name evidence="6" type="ORF">GLE_3791</name>
        <name evidence="7" type="ORF">LEN_1352</name>
        <name evidence="11" type="ORF">SAMN05421681_1102</name>
    </gene>
    <organism evidence="6 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 12">C3</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2016" name="DNA Res." volume="0" first="0" last="0">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer, Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M497-1</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="3">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">ATCC 29487</strain>
        </source>
    </reference>
    <reference evidence="7 15" key="4">
        <citation type="journal article" date="2017" name="DNA Res." volume="24" first="169" last="177">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
            <dbReference type="PubMed" id="28065880"/>
            <dbReference type="DOI" id=".1093/dnares/dsw055"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 15">M497-1</strain>
        </source>
    </reference>
    <reference evidence="8 14" key="5">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 14">B25</strain>
        </source>
    </reference>
    <reference evidence="10 16" key="6">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 16">OH11</strain>
        </source>
    </reference>
    <reference evidence="9 17" key="7">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the binding of tRNA to the ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="BAV96839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000023">
        <property type="protein sequence ID" value="ROU07182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNOG01000010">
        <property type="protein sequence ID" value="SDY02918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_022968186.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3791"/>
    <dbReference type="EnsemblBacteria" id="ALN59135">
        <property type="protein sequence ID" value="ALN59135"/>
        <property type="gene ID" value="GLE_3791"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAV96839">
        <property type="protein sequence ID" value="BAV96839"/>
        <property type="gene ID" value="LEN_1352"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61618">
        <property type="protein sequence ID" value="OPD61618"/>
        <property type="gene ID" value="BV903_23040"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY02918">
        <property type="protein sequence ID" value="SDY02918"/>
        <property type="gene ID" value="SAMN05421681_1102"/>
    </dbReference>
    <dbReference type="KEGG" id="lem:LEN_1352"/>
    <dbReference type="KEGG" id="lez:GLE_3791"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3735"/>
    <dbReference type="OMA" id="QFEIRVH"/>
    <dbReference type="OrthoDB" id="2012682at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000183696">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000218824">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_S10" evidence="5">
        <location>
            <begin position="7"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAV96839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD61618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW27362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROU07182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY02918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000183696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000218824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="103" mass="11717" checksum="D4DDED5B772C53FF" modified="2016-02-17" version="1">MADQKIRIRLKAYDHRLIDRSASEIVETAKRTGAQVRGPIPLPTKIERYTVLVSPHVDKDARDQYETRTHKRVLDIVDPNDKTVDALMKLELAAGVDVQIKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLS4</accession>
    <name>A0A0S2DLS4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptide-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">SH3 domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_21115</name>
        <name evidence="3" type="ORF">GLE_4318</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948957.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4318"/>
    <dbReference type="EnsemblBacteria" id="ALN59659">
        <property type="protein sequence ID" value="ALN59659"/>
        <property type="gene ID" value="GLE_4318"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4318"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4257"/>
    <dbReference type="OMA" id="FCHEEKY"/>
    <dbReference type="OrthoDB" id="1978757at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014593">
        <property type="entry name" value="UCP034961_SH3_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00018">
        <property type="entry name" value="SH3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07653">
        <property type="entry name" value="SH3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF034961">
        <property type="entry name" value="UCP034961_SH3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SSF50044"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="2">
        <location>
            <begin position="58"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="116" mass="13119" checksum="F8A0E9999AC5DD1E" modified="2016-02-17" version="1">MRAVVLADYRSQYPDPIAFARGAVVRLGERDDEWPAFAWTTLHDGRAGWAPLRWLRPLGDGRAQALRDYDARELDVAAGQDLRLIDEHGGWWWAQRDDGAQGWVPARHLQTIAEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLT0</accession>
    <name>A0A0S2DLT0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB-dependent outer membrane receptor</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="11">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FE772_19995</name>
        <name evidence="10" type="ORF">GLE_4075</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948763.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4075"/>
    <dbReference type="EnsemblBacteria" id="ALN59417">
        <property type="protein sequence ID" value="ALN59417"/>
        <property type="gene ID" value="GLE_4075"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4075"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4017"/>
    <dbReference type="OMA" id="FYRSRNH"/>
    <dbReference type="OrthoDB" id="71288at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010916">
        <property type="entry name" value="TonB_box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00430">
        <property type="entry name" value="TONB_DEPENDENT_REC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726583" evidence="7">
        <location>
            <begin position="23"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="53"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="295"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="223"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="224"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW27585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="798" mass="85822" checksum="7D39EE6A0B138E04" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLY6</accession>
    <name>A0A0S2DLY6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA-dihydrouridine(20/20a) synthase</fullName>
            <ecNumber evidence="6">1.3.1.91</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">U20-specific dihydrouridine synthase</fullName>
            <shortName evidence="6">U20-specific Dus</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA-dihydrouridine synthase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">dusA</name>
        <name evidence="10" type="ORF">GLE_4345</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,6-dihydrouridine(20) in tRNA + NAD(+) = H(+) + NADH + uridine(20) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:53340"/>
            <dbReference type="Rhea" id="RHEA-COMP:13533"/>
            <dbReference type="Rhea" id="RHEA-COMP:13534"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.91"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,6-dihydrouridine(20) in tRNA + NADP(+) = H(+) + NADPH + uridine(20) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:53336"/>
            <dbReference type="Rhea" id="RHEA-COMP:13533"/>
            <dbReference type="Rhea" id="RHEA-COMP:13534"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.91"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,6-dihydrouridine(20a) in tRNA + NAD(+) = H(+) + NADH + uridine(20a) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:53348"/>
            <dbReference type="Rhea" id="RHEA-COMP:13535"/>
            <dbReference type="Rhea" id="RHEA-COMP:13536"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,6-dihydrouridine(20a) in tRNA + NADP(+) = H(+) + NADPH + uridine(20a) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:53344"/>
            <dbReference type="Rhea" id="RHEA-COMP:13535"/>
            <dbReference type="Rhea" id="RHEA-COMP:13536"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6 7">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the Dus family. DusA subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the dus family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.91" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4345"/>
    <dbReference type="EnsemblBacteria" id="ALN59686">
        <property type="protein sequence ID" value="ALN59686"/>
        <property type="gene ID" value="GLE_4345"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4345"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4284"/>
    <dbReference type="OMA" id="LIYPYVD"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102264">
        <property type="term" value="F:tRNA-dihydrouridine20 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02041">
        <property type="entry name" value="DusA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001269">
        <property type="entry name" value="DUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004653">
        <property type="entry name" value="DusA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42907">
        <property type="entry name" value="PTHR42907"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006621">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00742">
        <property type="entry name" value="yjbN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 6 7" id="KW-0288">FMN</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="5 6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Dus" evidence="9">
        <location>
            <begin position="25"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6 8">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="27"/>
            <end position="29"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="221"/>
            <end position="223"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="243"/>
            <end position="244"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="site" description="Interacts with tRNA" evidence="6">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA; defines subfamily-specific binding signature" evidence="6">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA" evidence="6">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA; defines subfamily-specific binding signature" evidence="6">
        <location>
            <position position="307"/>
        </location>
    </feature>
    <feature type="site" description="Interacts with tRNA; defines subfamily-specific binding signature" evidence="6">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR006621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="343" mass="37676" checksum="16FEF0A29695B071" modified="2016-02-17" version="1">MAAMIPTPPTAVSPAIPAPQVRLSVAPMMDWTDSHCRVFHRAIAPHARLYTEMVHANAVIHGDRERLLAMDPVEHPVALQLGGSEPALLAQAARIGADWGFDEINLNCGCPSDRVQAGRFGACLMREPDLVAESVAAMIGACAVPVTVKCRLGVDDEHRFEVFLDFVDRVAAAGCRSFVVHARNAWLKGLSPKENREVPPLRYDWAYRLKRERPGLQVVVNGGIADLTEATAHLEHADGAMLGRAAYHDPYLLHRLDVAWFGGAERSRAELLRSLRPYVEAQLERGVFLKHIARHLLGLFHGERGGRAFRQILSEGAHRPGADWALIERALALTESFAARDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM11</accession>
    <name>A0A0S2DM11_LYSEN</name>
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        <submittedName>
            <fullName evidence="10">Sulfatase</fullName>
            <ecNumber evidence="10">3.1.6.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLE_4115</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.1.6.-" evidence="10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4115"/>
    <dbReference type="EnsemblBacteria" id="ALN59457">
        <property type="protein sequence ID" value="ALN59457"/>
        <property type="gene ID" value="GLE_4115"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4115"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4057"/>
    <dbReference type="OMA" id="WPINANT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016772">
        <property type="term" value="F:transferase activity, transferring phosphorus-containing groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
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        <property type="entry name" value="EptA-like_N"/>
    </dbReference>
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        <property type="entry name" value="PEA_transferase"/>
    </dbReference>
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        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30443">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
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            <end position="85"/>
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            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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        </location>
    </feature>
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        <location>
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        </location>
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        <location>
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            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="568" mass="62552" checksum="6A4DED80E41F7BF8" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM66</accession>
    <name>A0A0S2DM66_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase</fullName>
            <ecNumber evidence="2">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ydhF</name>
        <name evidence="2" type="ORF">GLE_4378</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.-.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949004.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4378"/>
    <dbReference type="EnsemblBacteria" id="ALN59719">
        <property type="protein sequence ID" value="ALN59719"/>
        <property type="gene ID" value="GLE_4378"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4378"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4317"/>
    <dbReference type="OMA" id="VVYAWVM"/>
    <dbReference type="OrthoDB" id="1367386at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="11"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="295" mass="32398" checksum="80E0C8A12BA0370C" modified="2016-02-17" version="1">MSASESLTLSPIVAGCWRMAEWKLDAAGRLRWIEQALELGIDSFDHADIYGDYSVEALFGEALALQPGLRQRIRVVSKCGIKLTSAQRPTHAIKSYDSSRAHVLASVEHSLRALRTDYLDLLLIHRPDLLMDADELAATFAQLKAAGKVLHVGVSNHTPAQLALLHARHPLATHQVELSPLHLPPLDDGTLEQCQALRLRPMLWSPLAGGRLFGGGDECAERVRAVLADLGRRHGGASVATMAYAWLLRHPTRPWPITGSGREQGLRDAVDALRIELSAQDWYEVWQASAGREVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMG3</accession>
    <name>A0A0S2DMG3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arsenical resistance operon repressor</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">arsR</name>
        <name evidence="3" type="ORF">FE772_19670</name>
        <name evidence="2" type="ORF">GLE_4010</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057950246.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59352">
        <property type="protein sequence ID" value="ALN59352"/>
        <property type="gene ID" value="GLE_4010"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4010"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3947"/>
    <dbReference type="OMA" id="QETRLHI"/>
    <dbReference type="OrthoDB" id="1800563at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="109" mass="11653" checksum="75CC167B58DEEF87" modified="2016-02-17" version="1">MEIKSAVTLLAALAQETRLSVFRLLVEQGTDGLPAGQIAERLDISPATLSFHLKELTHAGLTLSRQEGRFVIYSAHYEAMNGLLSFLTENCCAGSPCDATASACAPSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMH6</accession>
    <name>A0A0S2DMH6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Calcium-binding EF-hand containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">EF-hand domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BV903_11685</name>
        <name evidence="6" type="ORF">FE772_21305</name>
        <name evidence="4" type="ORF">GLE_4359</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">C3</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000028">
        <property type="protein sequence ID" value="OPD63709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948991.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000028.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4359"/>
    <dbReference type="EnsemblBacteria" id="ALN59700">
        <property type="protein sequence ID" value="ALN59700"/>
        <property type="gene ID" value="GLE_4359"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63709">
        <property type="protein sequence ID" value="OPD63709"/>
        <property type="gene ID" value="BV903_11685"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4359"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4298"/>
    <dbReference type="OMA" id="AKHHAGM"/>
    <dbReference type="OrthoDB" id="2054772at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="SSF47473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595453" evidence="2">
        <location>
            <begin position="27"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="82"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD63709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW27802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="126" mass="12516" checksum="F64B61F49BDA635B" modified="2016-02-17" version="1">MNIKSRKPLIAALALTAALAAPMAFAQSATEQAPPTGDAATPAATAQEPAAATAAPAPTAQKKSWADVDTDKSGNLSKNEAAAVPALSQVFEQADSDSNGQLTPDEYKNYVAKAQSGGGASSSGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMM6</accession>
    <name>A0A0S2DMM6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948988.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4356"/>
    <dbReference type="EnsemblBacteria" id="ALN59697">
        <property type="protein sequence ID" value="ALN59697"/>
        <property type="gene ID" value="GLE_4356"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4356"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4295"/>
    <dbReference type="OMA" id="QVMTKGD"/>
    <dbReference type="OrthoDB" id="1621438at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594987" evidence="1">
        <location>
            <begin position="36"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="155" mass="15694" checksum="ED180C688E69AD46" modified="2016-02-17" version="1">MSQVSVHAPASTRLRGAALAAALLAALALPGTAAADTLTCKLKFSMSGWSVFYKTSSGSGTIHCSNGQSMSVKIRAKGGGLTVGKSRIDRGTGEFAGVRRISDVLGSYATAEAHAGAARSSKAQVMTKGEVSLALAGTGQGWDLGVAFGKFTISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMP2</accession>
    <name>A0A0S2DMP2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Glutamine-dependent NAD(+) synthetase</fullName>
            <ecNumber evidence="5 6">6.3.5.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 6">NAD(+) synthase [glutamine-hydrolyzing]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 10" type="primary">nadE</name>
        <name evidence="11" type="ORF">BV903_18435</name>
        <name evidence="12" type="ORF">FE772_20135</name>
        <name evidence="10" type="ORF">GLE_4106</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">C3</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>ATP + deamido-NAD(+) + H2O + L-glutamine = AMP + diphosphate + H(+) + L-glutamate + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:24384"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5 6">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the NAD synthetase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 6">In the C-terminal section; belongs to the NAD synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.1" evidence="5 6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000050">
        <property type="protein sequence ID" value="OPD62455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948788.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000050.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4106"/>
    <dbReference type="EnsemblBacteria" id="ALN59448">
        <property type="protein sequence ID" value="ALN59448"/>
        <property type="gene ID" value="GLE_4106"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62455">
        <property type="protein sequence ID" value="OPD62455"/>
        <property type="gene ID" value="BV903_18435"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4106"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4048"/>
    <dbReference type="OMA" id="VLMPSPY"/>
    <dbReference type="OrthoDB" id="1152435at2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00334"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003952">
        <property type="term" value="F:NAD+ synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008795">
        <property type="term" value="F:NAD+ synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000257">
        <property type="term" value="F:nitrilase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00553">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02090">
        <property type="entry name" value="NadE_glutamine_dep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014445">
        <property type="entry name" value="Gln-dep_NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003694">
        <property type="entry name" value="NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000132">
        <property type="entry name" value="Nitrilase/CN_hydratase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090">
        <property type="entry name" value="PTHR23090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006630">
        <property type="entry name" value="NADS_GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00552">
        <property type="entry name" value="nadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00920">
        <property type="entry name" value="NITRIL_CHT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 6 8" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="9">
        <location>
            <begin position="5"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="46"/>
        </location>
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            <position position="119"/>
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        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:58359"/>
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        <location>
            <position position="177"/>
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        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:58359"/>
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        <location>
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        <location>
            <begin position="292"/>
            <end position="299"/>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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        <location>
            <position position="375"/>
        </location>
        <ligand>
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        <source>
            <dbReference type="EMBL" id="ALN59448.1"/>
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        <source>
            <dbReference type="EMBL" id="OPD62455.1"/>
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        <source>
            <dbReference type="EMBL" id="QCW27603.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
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    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
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    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="545" mass="59203" checksum="C29CFD36B68C2896" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMQ1</accession>
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                <person name="Feng T."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <text evidence="1">Belongs to the GST superfamily.</text>
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            <dbReference type="PROSITE" id="PS50405"/>
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        <source>
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</entry>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN59936">
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    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="56"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="378" mass="40984" checksum="8C290F8018E5B80C" modified="2016-02-17" version="1">MSDAMNVAMPAAATGWSGGRLAVVVAACLGAAACAGAPQRAAEQGTDDAARAEQVDALLADYRGRAPGASVLVLRDGRPVLRRGYGMAVLEDSVAAAPRTNYRLASVSKQFTAAAVLLLAQDGALDLDDPIKRWLPSLPQACDAITIRQILSHQSGLIDYEDVMPARFDADARQMRDADVLVALEGQDRTYFAPGGGYRYSNSGYALLALTVQKASGRSFAAFLRERIFAPLDMRDTVAYQRGVSQVAHRAYGYSFEDGRWRRTDQSPTSAVLGDGGIYSSIDDLAKWDAALYDGRLLSDASRRLAFAAHTPTDVAEVGYGYGWRITGETLWHSGETIGFRNVIVRWPQRRLTVVMLSNRNDPEPYRTALKIGALYLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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        <property type="gene ID" value="GLE_4765"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4765"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4698"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="145" mass="16208" checksum="1CCE77E152162238" modified="2016-02-17" version="1">MNEKNQRETLSELTAADLLILPLREGTAGFDRLDQALQDHFGSNNAIGATIRLEAQQPVTLHDGYVIRRYLRPDSSRHLLVELDSEPCFPVARGVELTEPDPRWMDYYQQTGIYKAAGAGMSVGFAADGFRRECITSLEIAKIPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNL1</accession>
    <name>A0A0S2DNL1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-binding response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BV903_06630</name>
        <name evidence="9" type="ORF">D9T17_05040</name>
        <name evidence="8" type="ORF">FE772_23745</name>
        <name evidence="6" type="ORF">GLE_4889</name>
    </gene>
    <organism evidence="6 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 10">C3</strain>
        </source>
    </reference>
    <reference evidence="7 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">OH11</strain>
        </source>
    </reference>
    <reference evidence="8 13" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 13">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000012">
        <property type="protein sequence ID" value="OPD64707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000014">
        <property type="protein sequence ID" value="ROU08280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949394.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000014.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4889"/>
    <dbReference type="EnsemblBacteria" id="ALN60230">
        <property type="protein sequence ID" value="ALN60230"/>
        <property type="gene ID" value="GLE_4889"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64707">
        <property type="protein sequence ID" value="OPD64707"/>
        <property type="gene ID" value="BV903_06630"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4889"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4820"/>
    <dbReference type="OMA" id="VKMTPVI"/>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="128"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="128"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN60230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD64707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW28211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROU08280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="232" mass="26167" checksum="982B4D46990F400D" modified="2016-02-17" version="1">MNKVLLIEDDARLAGLISEYLQRYDFQTSVVLRGDLALPAIENDPPDVIVLDLMLPGMDGFDVCRQIRKQSSLPIVMLTARADLFDQVTGLEVGADDYVLKPVEPRLLLARLRAVLRRSQAQPQAAGPSILSYGGLQIDLTARQVRWKGEEIDLKTADYNLFVILAQAAGRVLSRDELLRRWRGIGFDGVDRTVDVSISRLRRHFADDAHEPRKIKTVWGRGYLFSPIAWED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNN6</accession>
    <name>A0A0S2DNN6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_4922</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60263">
        <property type="protein sequence ID" value="ALN60263"/>
        <property type="gene ID" value="GLE_4922"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4922"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4851"/>
    <dbReference type="OMA" id="LPYRSHF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="3">
        <location>
            <begin position="73"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="383" mass="40798" checksum="8CBCDCB96840EE01" modified="2016-02-17" version="1">MNPHPSVPPRAREDRRANLSAVAPAASRRDPSAGATPPPLACAAPAPVALSPPALPPPSPLSPAFSASYAGVVAFIAVATEGSFARAADRLGIGRSAVSRSVQKLEGQVGARLFSRTTRSTSLTPEGELFFDQCRPGMERIVQALEDLRELRDGPPRGQLRIGAAPGFGRKVLAPLLGEFRRRHPGVAIELVLDERTPELAVDRLDLAFRDGRLDDSQVIAKRLIPMQWLVCAAPDYARRHGLPASPAELARHACLNRRLGGGRLRAWEFKVDGRAQAFAPAAELAFNDDELLLHAAVDGQGLAQLPAYLACDALRSGALVHCLGGYAPDDGGHYLCYLSREQLPKRVRAFIDFATARVRALDLDCALDHACAAAPAPLAAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNS1</accession>
    <name>A0A0S2DNS1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">(2Fe-2S)-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_14145</name>
        <name evidence="2" type="ORF">GLE_4610</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000036">
        <property type="protein sequence ID" value="OPD63270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949179.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4610"/>
    <dbReference type="EnsemblBacteria" id="ALN59951">
        <property type="protein sequence ID" value="ALN59951"/>
        <property type="gene ID" value="GLE_4610"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63270">
        <property type="protein sequence ID" value="OPD63270"/>
        <property type="gene ID" value="BV903_14145"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4610"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4545"/>
    <dbReference type="OMA" id="RPNQRAC"/>
    <dbReference type="OrthoDB" id="1885467at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042204">
        <property type="entry name" value="2Fe-2S-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="82" mass="8588" checksum="2BF7DF6EC028EA58" modified="2016-02-17" version="1">MSAAPVRLDIDGVAVEVPAGASVAAAVALAAPHFRRSRSGQPRAPLCGMGVCFECRVRIDGVEHQRSCLVPAREGMRVACDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNU8</accession>
    <name>A0A0S2DNU8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4861</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949370.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4861"/>
    <dbReference type="EnsemblBacteria" id="ALN60202">
        <property type="protein sequence ID" value="ALN60202"/>
        <property type="gene ID" value="GLE_4861"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4861"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4792"/>
    <dbReference type="OMA" id="HCGQENI"/>
    <dbReference type="OrthoDB" id="1802360at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022134">
        <property type="entry name" value="DUF3667"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="361"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="400"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="435"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="476"/>
            <end position="496"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="498" mass="54681" checksum="CE9F04AC116B8548" modified="2016-02-17" version="1">MSATTEATAASAGHGHDHDHDRPSHCENCRADLHGHYCHECGQSVHNPVRNFGHAVEEVFESFWHLDGRVFRTLRDLLSPGKVARDYLAGHRVRYLPPLRLFVIASVLTFFVAQFAIHVETATHFDIDTAQSTTVRLGNVKKQMRAAQSVVEVEELRARIVGELRVAAAAAPVARSTIEASIAGVQRQADKRIEALRAEQGLSAQDVASQRAEGDRLAAAPKPGSMEAAKDLAEVERLRDARIARLRDEHAAQAAGLRDASTLAAQIRVANAEAGCRIAQLQIGHAASSEGARAHDKDRARYGETDCDGMDDPISFNGKPWDAKTNPLTVTWWPRFANDWLNRQVGKGEANFQRATKDPALYIHALIGAIPSALFLMVPIFALLLKIAYLGSGRGYLEHLVVALYSHTYLCLALLAMFVLMLLGDAIAPHWAGFAWIKGLGIGLLWLWMPIYLLLMEKRVYANGWALTLLRYTLIGGAYFFLMSLATAGIMAAAIVRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP27</accession>
    <name>A0A0S2DP27_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HTH type transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Helix-turn-helix domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_12040</name>
        <name evidence="5" type="ORF">FE772_24030</name>
        <name evidence="3" type="ORF">GLE_4959</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000029">
        <property type="protein sequence ID" value="OPD63651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60300">
        <property type="protein sequence ID" value="ALN60300"/>
        <property type="gene ID" value="GLE_4959"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63651">
        <property type="protein sequence ID" value="OPD63651"/>
        <property type="gene ID" value="BV903_12040"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4959"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4886"/>
    <dbReference type="OMA" id="DSQVGHI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="24"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD63651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW28259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="237" mass="25780" checksum="3A8A8D9203FF3910" modified="2016-02-17" version="1">MPAKRSKTVIVAAPAAAPNPGVALRALRRQRGWTLAEIGARTGLPISTLSKIENGKMSLSFDKLTRIAQGLEVDIGELFSNQPPAGNDAFSGRRSITRAGEGYAIRTENYDHLYPASELLNKRLVPIIAEVRARSLDEFGELIRHSGEEFAMVLEGAIELHTELYAPARLETGDSIYFDSAMGHAYIAAAPGRCRVLAVCSGGEAHLREAMARQDGARQDAARYEPPRPSRARREDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP64</accession>
    <name>A0A0S2DP64_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4603</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949174.1">
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_4603"/>
    <dbReference type="EnsemblBacteria" id="ALN59944">
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        <property type="gene ID" value="GLE_4603"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4603"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4538"/>
    <dbReference type="OMA" id="NHWWDGD"/>
    <dbReference type="OrthoDB" id="1915613at2"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595494" evidence="1">
        <location>
            <begin position="21"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="256" mass="27149" checksum="40193B56FFF6EF24" modified="2016-02-17" version="1">MPRYVPALLFAAAMTLAGCASTRADRAGDGAAQPQLVLVTTADWNATQGRLQRYLFEGGQWLAVGEPVAVSIGRNGAAWGRGLRAAPDDGGPLKREGDGRAPAGMFAVGTAFGYAETAQTALAYAPMSASHYCIDVPASPLYDRIVDARRVGDEAVKGSTEPMRRDLHADGDPRYRLGFVIAHNPAHVPGAGSCIFAHLQRAPGEPTAGCTAMSDAAMDELLAWLRPQARPLFVLLPQAQYRAVWKAWGLPQPVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPB3</accession>
    <name>A0A0S2DPB3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_23680</name>
        <name evidence="2" type="ORF">GLE_4876</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949381.1">
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60217">
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        <property type="gene ID" value="GLE_4876"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4876"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4807"/>
    <dbReference type="OrthoDB" id="1962607at2"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726739" evidence="1">
        <location>
            <begin position="27"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="142" mass="14960" checksum="33B9E9EF7228289A" modified="2016-02-17" version="1">MEVSKMLIAAGFAAALSLVAVAPARAGDLSGAQLTCYVDTFAFDVPQAQWCHSTWTPGTATNPSVAMFEVTGLTAGNYSFAWTDLETGQTPSGCGNAQYCIVPIATETRGDGEARARVVVTDTATGAQRSFDATAWYWDGYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPP4</accession>
    <name>A0A0S2DPP4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">STAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5237</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5237"/>
    <dbReference type="EnsemblBacteria" id="ALN60578">
        <property type="protein sequence ID" value="ALN60578"/>
        <property type="gene ID" value="GLE_5237"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5237"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5155"/>
    <dbReference type="OMA" id="ACIRTQG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13466">
        <property type="entry name" value="STAS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="1">
        <location>
            <begin position="15"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="95" mass="9598" checksum="F9E74BA92BB4C3DB" modified="2016-02-17" version="1">MSPAPASVRRDGETLAFAGVLDRAAAAALWPQARPLAPGARRFDLTGVASVDSAGLALLAELAAQAPGVAVVGEPTGLAELRAAYRLDDSLGFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ35</accession>
    <name>A0A0S2DQ35_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sigma factor regulatory protein, FecR/PupR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_5058</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949522.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5058"/>
    <dbReference type="EnsemblBacteria" id="ALN60399">
        <property type="protein sequence ID" value="ALN60399"/>
        <property type="gene ID" value="GLE_5058"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5058"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4986"/>
    <dbReference type="OMA" id="IMVTSGH"/>
    <dbReference type="OrthoDB" id="1381035at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006860">
        <property type="entry name" value="FecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032623">
        <property type="entry name" value="FecR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012373">
        <property type="entry name" value="Ferrdict_sens_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30273">
        <property type="entry name" value="PTHR30273"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16220">
        <property type="entry name" value="DUF4880"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04773">
        <property type="entry name" value="FecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018266">
        <property type="entry name" value="FecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4880" evidence="4">
        <location>
            <begin position="11"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="FecR" evidence="3">
        <location>
            <begin position="152"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="364" mass="38865" checksum="C22D3107B11926EE" modified="2016-02-17" version="1">MAGSREIEQIAAQWLARRDSGDWPAAAQAELEAWLARATAHRVAFVRLQAAWRQAGRLQALAAGEGGVPARAAWDEVAPPRAPFTSVDAGADAGEDRDRVAPPPRADALTFQPRRAPARASRGPFAAAAAVAALAVGLGWGWLHYGAIERASYRTALGATDEVALADGSRATLSSDSRIEVALSGARRRVELAQGEAFFDVAKDPGRPFAVEAGARRVVAVGTHFSVRRDGADLRVVVTEGTVRLESEPVGGHPQPTTLLPAGSIALAGPNGVLVRSVAVEEAERYVDWRHGFLVFRDTPLAQAAAEFNRYSARKLVIADTAAGELRVGGNFRWSNAEMFVGLLEQAMPVRAERLPDRIVLHSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ69</accession>
    <name>A0A0S2DQ69_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Isocitrate dehydrogenase [NADP]</fullName>
            <ecNumber evidence="3">1.1.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">icd</name>
        <name evidence="7" type="ORF">BV903_05140</name>
        <name evidence="9" type="ORF">D9T17_02955</name>
        <name evidence="8" type="ORF">FE772_00210</name>
        <name evidence="6" type="ORF">GLE_5386</name>
    </gene>
    <organism evidence="6 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 10">C3</strain>
        </source>
    </reference>
    <reference evidence="7 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">OH11</strain>
        </source>
    </reference>
    <reference evidence="8 13" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 13">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19629"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.1.1.42" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000010">
        <property type="protein sequence ID" value="OPD64880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000008">
        <property type="protein sequence ID" value="ROU08765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949768.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000008.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5386"/>
    <dbReference type="EnsemblBacteria" id="ALN60727">
        <property type="protein sequence ID" value="ALN60727"/>
        <property type="gene ID" value="GLE_5386"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64880">
        <property type="protein sequence ID" value="OPD64880"/>
        <property type="gene ID" value="BV903_05140"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5386"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5301"/>
    <dbReference type="OMA" id="CVRPCRY"/>
    <dbReference type="OrthoDB" id="1551125at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004450">
        <property type="term" value="F:isocitrate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004439">
        <property type="entry name" value="Isocitrate_DH_NADP_dimer_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43504">
        <property type="entry name" value="PTHR43504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00183">
        <property type="entry name" value="prok_nadp_idh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Iso_dh" evidence="5">
        <location>
            <begin position="29"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN60727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD64880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW24321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROU08765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="442" mass="47754" checksum="99BAEE0DE6C3B60C" modified="2016-02-17" version="1">MTEFVATPPSGGAKITKTPTGLNVPDRPIIPFIEGDGTGPDIWRASVRVLDAAVAKAYGGQKKIEWLEVYAGEKANNTYGTWLPDGTVQACRDYLVSIKGPLTTPVGGGIRSLNVALRQMLDLYVCLRPVRWFEGVPSPVKKPGDVDMVIFRENTEDIYAGIEWAGGSADAKKVLDFLQAEFPQAFDKIRFGTQAKIDAWQDELVAVGAPKRELGVDVGIGIKPVSFLGTTRLVHAAIEYAIENKRKSVTLVHKGNIMKYTEGGFRDWGYQIAREAFGAVELDGGPWHVIPEGKPGAGLVIKDAIADAFLQQILLRPKEYDVSATLNLNGDYLSDALAAQVGGIGIAPGANINYVTGHAVFEATHGTAPKYADLDKVNPGSVILSGEMMLRYLGWTEAADAIIAAMDKAIASKRVTYDFARLMDGATEVKCSEFADEIIKHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ82</accession>
    <name>A0A0S2DQ82_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5228</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60569">
        <property type="protein sequence ID" value="ALN60569"/>
        <property type="gene ID" value="GLE_5228"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5228"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5146"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021529">
        <property type="entry name" value="DUF2798"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11391">
        <property type="entry name" value="DUF2798"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="75" mass="7903" checksum="B7B770A148257731" modified="2016-02-17" version="1">MSALIGLAVVVFRQGLAQGAEEAWMLAWVLAFTIALPAAMLLMPAIGAVLAHYTRDDKHHVIIPVVGEKVPGAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQD4</accession>
    <name>A0A0S2DQD4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_00180</name>
        <name evidence="2" type="ORF">GLE_5379</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949762.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5379"/>
    <dbReference type="EnsemblBacteria" id="ALN60720">
        <property type="protein sequence ID" value="ALN60720"/>
        <property type="gene ID" value="GLE_5379"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5379"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5294"/>
    <dbReference type="OMA" id="ECWIYGS"/>
    <dbReference type="OrthoDB" id="1938768at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025644">
        <property type="entry name" value="DUF4344"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14247">
        <property type="entry name" value="DUF4344"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="346" mass="38103" checksum="376F801C91030102" modified="2016-02-17" version="1">MVQKIIIGVLAAALIAVCSIWGYSTWQKQQAAAPAPVAAPAAAAVVEPAKPVDAALPAETAPVAAEAAATEKADGTHFTYKYVSPRSPQLLSIYNMASEIDVLRNLPEVNQLDGWLTLPRPINFITAECGTINAFYARDKGDVVLCYEMLDMLVRQGAAIAQANGGSTRDQLKYLMANLRFLMLHETGHALVDMLDLPQTGREEDAVDQLATTLMLSFVSADESEGDIAQNLQLASNFFLLTDSGNHDMATYADEHSVGAQRFFNLQCMIYGHDPGKYLRIVTSGRLPEARALRCEDESKQITRNWMRLIEPNIAPKHRMTREEEQAKIDQIKQKQVENAPAPYVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQJ4</accession>
    <name>A0A0S2DQJ4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADPH-dependent 7-cyano-7-deazaguanine reductase</fullName>
            <ecNumber evidence="2">1.7.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">7-cyano-7-carbaguanine reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">NADPH-dependent nitrile oxidoreductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">PreQ(0) reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 4" type="primary">queF</name>
        <name evidence="5" type="ORF">FE772_00255</name>
        <name evidence="4" type="ORF">GLE_5396</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>7-aminomethyl-7-carbaguanine + 2 NADP(+) = 7-cyano-7-deazaguanine + 3 H(+) + 2 NADPH</text>
            <dbReference type="Rhea" id="RHEA:13409"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:45075"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58703"/>
            <dbReference type="EC" id="1.7.1.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.7.1.13" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949777.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5396"/>
    <dbReference type="EnsemblBacteria" id="ALN60737">
        <property type="protein sequence ID" value="ALN60737"/>
        <property type="gene ID" value="GLE_5396"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5396"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5311"/>
    <dbReference type="OMA" id="QCVERIY"/>
    <dbReference type="OrthoDB" id="1525536at2"/>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046857">
        <property type="term" value="F:oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033739">
        <property type="term" value="F:preQ1 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00817">
        <property type="entry name" value="QueF_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029500">
        <property type="entry name" value="QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029139">
        <property type="entry name" value="QueF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016428">
        <property type="entry name" value="QueF_type2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14489">
        <property type="entry name" value="QueF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14819">
        <property type="entry name" value="QueF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004750">
        <property type="entry name" value="Nitrile_oxidored_YqcD_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03138">
        <property type="entry name" value="QueF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="QueF_N" evidence="3">
        <location>
            <begin position="14"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="81"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="216"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="active site" description="Thioimide intermediate" evidence="2">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="83"/>
            <end position="84"/>
        </location>
        <ligand>
            <name>NADPH</name>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="245"/>
            <end position="246"/>
        </location>
        <ligand>
            <name>NADPH</name>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW24330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="270" mass="29282" checksum="C39FDE4EE76E1AAA" modified="2016-02-17" version="1">MTAHELPLGRHVDYPREYDASLLFPIARALGREHIGVDDAAPPFVGHDRWHAYELSWLDGRGKPRVATATVSVPATSPHLIESKSLKLYLNSFNSSRFDSAQAVLDTIAADLSAAAGAPVAVVFGLPPIDGDGTAESIDGLDVAIDDYGPPNAAHLSADAGEIVEETLNSALLKSNCPVTGQPDWARVVIAYRGPRLDRAGLLRYLVSFRDHAEFHEQCVERIHADLTRIAKPQWLSVEARYTRRGGLDINPWRGSPGLAAPAAGRDERQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQV9</accession>
    <name>A0A0S2DQV9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Enterobactin synthase component D</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">4'-phosphopantetheinyl transferase EntD</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Enterochelin synthase D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLE_5440</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. Plays an essential role in the assembly of the enterobactin by catalyzing the transfer of the 4'-phosphopantetheine (Ppant) moiety from coenzyme A to the apo-domains of both EntB (ArCP domain) and EntF (PCP domain) to yield their holo-forms which make them competent for the activation of 2,3-dihydroxybenzoate (DHB) and L-serine, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>apo-[aryl-carrier protein] + CoA = adenosine 3',5'-bisphosphate + H(+) + holo-[aryl-carrier protein]</text>
            <dbReference type="Rhea" id="RHEA:48404"/>
            <dbReference type="Rhea" id="RHEA-COMP:15903"/>
            <dbReference type="Rhea" id="RHEA-COMP:17557"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>apo-[peptidyl-carrier protein] + CoA = adenosine 3',5'-bisphosphate + H(+) + holo-[peptidyl-carrier protein]</text>
            <dbReference type="Rhea" id="RHEA:46228"/>
            <dbReference type="Rhea" id="RHEA-COMP:11479"/>
            <dbReference type="Rhea" id="RHEA-COMP:11480"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Siderophore biosynthesis; enterobactin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">EntB, EntD, EntE, and EntF form a multienzyme complex called enterobactin synthase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the P-Pant transferase superfamily. EntD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949810.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5440"/>
    <dbReference type="EnsemblBacteria" id="ALN60781">
        <property type="protein sequence ID" value="ALN60781"/>
        <property type="gene ID" value="GLE_5440"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5440"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5356"/>
    <dbReference type="OMA" id="CAVHRES"/>
    <dbReference type="OrthoDB" id="1542506at2"/>
    <dbReference type="UniPathway" id="UPA00017"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009366">
        <property type="term" value="C:enterobactin synthetase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009239">
        <property type="term" value="P:enterobactin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041354">
        <property type="entry name" value="4PPT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003542">
        <property type="entry name" value="Enbac_synth_compD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38096">
        <property type="entry name" value="PTHR38096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17837">
        <property type="entry name" value="4PPT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01399">
        <property type="entry name" value="ENTSNTHTASED"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="SSF56214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0259">Enterobactin biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="4PPT_N" evidence="13">
        <location>
            <begin position="62"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="ACPS" evidence="12">
        <location>
            <begin position="133"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF17837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN60781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="251" mass="26807" checksum="F21CD850E6C49F52" modified="2016-02-17" version="1">MTADAPAAADSESSDPGQAFLREAGDIEIEAFGRRFAGHACRFDLGAYRDGLFARYGIELPAQLDRAVPKRRSEFLAGRLCARRALDRLGAAPATVAIGRDREPLWPPGTIASITHAGDRALCLAASDADTLGLGVDIERPLDAARAAEIRGLVVDADEQARIADGFADPAAGLAATFSAKESLYKALFPQVRRLFGFEAMRLVRVGPQRLDFACAEDLAPGVRRGQGFAAHYRFDADGGVLSLVWLPRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DR57</accession>
    <name>A0A0S2DR57_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyridoxine 5'-phosphate synthase</fullName>
            <shortName evidence="2">PNP synthase</shortName>
            <ecNumber evidence="2">2.6.99.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 3" type="primary">pdxJ</name>
        <name evidence="3" type="ORF">GLE_5323</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate = H(+) + 2 H2O + phosphate + pyridoxine 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:15265"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:58589"/>
            <dbReference type="EC" id="2.6.99.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homooctamer; tetramer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PNP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.6.99.2" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949721.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5323"/>
    <dbReference type="EnsemblBacteria" id="ALN60664">
        <property type="protein sequence ID" value="ALN60664"/>
        <property type="gene ID" value="GLE_5323"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5323"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5240"/>
    <dbReference type="OMA" id="SNAGWDT"/>
    <dbReference type="OrthoDB" id="1159993at2"/>
    <dbReference type="UniPathway" id="UPA00244">
        <property type="reaction ID" value="UER00313"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033856">
        <property type="term" value="F:pyridoxine 5'-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00279">
        <property type="entry name" value="PdxJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004569">
        <property type="entry name" value="PyrdxlP_synth_PdxJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036130">
        <property type="entry name" value="Pyridoxine-5'_phos_synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30456">
        <property type="entry name" value="PTHR30456"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03740">
        <property type="entry name" value="PdxJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63892">
        <property type="entry name" value="SSF63892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00559">
        <property type="entry name" value="pdxJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="3-amino-2-oxopropyl phosphate binding" evidence="2">
        <location>
            <begin position="224"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>3-amino-2-oxopropyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>3-amino-2-oxopropyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>3-amino-2-oxopropyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="2">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="251" mass="26504" checksum="823C2CEB825157E6" modified="2016-02-17" version="1">MTVLSVNVNKIAVLRNSRGGAEPDVVRAARACLDAGAHGITVHPRPDARHIRDYDVYALAELAHARGVEFNIEGNPFAPPRAGYPGMLELCRQTRPAQATLVPDGDDQLTSDHGFDFQRDADTLRPRIAELRELGCRISVFADADRDGIERAAELGAQRVELYTGPYAEAFAAGDAGAALAAFADAARRAQAAGLGVNAGHDLSQANLGAFLRAVPDVLEVSIGHALIGEALYDGLDATVRGYLAVIAGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAA0</accession>
    <name>A0A0S2DAA0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Recombination-associated protein RdgC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">rdgC</name>
        <name evidence="7" type="ORF">BV903_05845</name>
        <name evidence="8" type="ORF">FE772_01500</name>
        <name evidence="6" type="ORF">GLE_0115</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">C3</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">May be involved in recombination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 5">Cytoplasm</location>
            <location evidence="2 5">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the RdgC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000010">
        <property type="protein sequence ID" value="OPD65004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945807.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0115"/>
    <dbReference type="EnsemblBacteria" id="ALN55474">
        <property type="protein sequence ID" value="ALN55474"/>
        <property type="gene ID" value="GLE_0115"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65004">
        <property type="protein sequence ID" value="OPD65004"/>
        <property type="gene ID" value="BV903_05845"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0115"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.118"/>
    <dbReference type="OMA" id="RFDADFT"/>
    <dbReference type="OrthoDB" id="655073at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009295">
        <property type="term" value="C:nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00194">
        <property type="entry name" value="RdgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007476">
        <property type="entry name" value="RdgC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38103">
        <property type="entry name" value="PTHR38103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04381">
        <property type="entry name" value="RdgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN55474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD65004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW24545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="303" mass="33490" checksum="7A11B29C88D5D6D1" modified="2016-02-17" version="1">MFFRNLTFFRFPTTHDLAELDKGLEECRLKPVGPLELSSRGFISPFGRADEEAAISNRIGSAIWLTVGGEDRLLPGAVINDMLAKKLAEIEQKEGRKPGGRTRKRLKDELITDLMPRAFIKPSRTDAIIDLEHGLVIVDSSSRKTAENVISEIRRAVGSFPALPLNAEVAPRSILTGWVAGEPLPDGIMLGDECELRDPVDQGAVVKCQRQELESDEIAKHLETGKQVTRLALSLDDHVSFVIGEDLIVRKFKLLDGAVDQLEHSDGDGLRAELDARFALMSAEVKRLFVVMEKALKLSKVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAP0</accession>
    <name>A0A0S2DAP0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Isocitrate lyase</fullName>
            <ecNumber evidence="1">4.1.3.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Isocitrase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Isocitratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">aceA</name>
        <name evidence="10" type="ORF">FE772_01955</name>
        <name evidence="9" type="ORF">GLE_0223</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>D-threo-isocitrate = glyoxylate + succinate</text>
            <dbReference type="Rhea" id="RHEA:13245"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="EC" id="4.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Can also use Mn(2+) ion.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.1" evidence="1"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945882.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0223"/>
    <dbReference type="EnsemblBacteria" id="ALN55582">
        <property type="protein sequence ID" value="ALN55582"/>
        <property type="gene ID" value="GLE_0223"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0223"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.225"/>
    <dbReference type="OMA" id="LEKDWAE"/>
    <dbReference type="OrthoDB" id="152545at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004451">
        <property type="term" value="F:isocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00377">
        <property type="entry name" value="ICL_PEPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039556">
        <property type="entry name" value="ICL/PEPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006254">
        <property type="entry name" value="Isocitrate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018523">
        <property type="entry name" value="Isocitrate_lyase_ph_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21631">
        <property type="entry name" value="PTHR21631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00463">
        <property type="entry name" value="ICL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001362">
        <property type="entry name" value="Isocit_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01346">
        <property type="entry name" value="isocit_lyase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00161">
        <property type="entry name" value="ISOCITRATE_LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="89"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="189"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="310"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN55582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW24623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="433" mass="47116" checksum="C28F586A7BED549F" modified="2016-02-17" version="1">MSHTLPTADQLRHEWATDPRWAGITRPYSAEDVVRLRGTVPVEHSIAKLGAAKLWNSLHTEDFVNALGALTGNQAMQQVKAGLKAIYLSGWQVAADANIAGEMYPDQSLYPANSVPQVVRRINNTLLRADQIQCAEGTGDIDFLQPIVADAEAGFGGVLNAFELMKGMIEAGASGVHFEDQLASVKKCGHMGGKVLVPTREAVEKLVAARLAADVMGVPTLIVARTDAEAADLLTADIDPNDQPFTTGERTNEGFYKTRNGLDQAISRGLAYAPYADLVWCETGKPDLEFARKFAEAIHAQFPGKLLAYNCSPSFNWKKNLDDATIAKFQKEIATYGYKFQFITLAGFHSLNYGMFNLAHGYARRQMSAFVELQEAEFAAAEKGFTAVKHQREVGTGYFDAVTQTIQGGQSSTVALKGSTEEEQFHESKKAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAW9</accession>
    <name>A0A0S2DAW9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0190"/>
    <dbReference type="EnsemblBacteria" id="ALN55549">
        <property type="protein sequence ID" value="ALN55549"/>
        <property type="gene ID" value="GLE_0190"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0190"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.192"/>
    <dbReference type="OMA" id="ETCANIG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012878">
        <property type="entry name" value="Glyco_hydro_127"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07944">
        <property type="entry name" value="Glyco_hydro_127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="636" mass="69652" checksum="75E28C3F01B7482B" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB36</accession>
    <name>A0A0S2DB36_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Phosphomannomutase</fullName>
            <ecNumber evidence="11">5.4.2.8</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="12">Phosphomannomutase/phosphoglucomutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">BV903_12970</name>
        <name evidence="11" type="ORF">GLE_0254</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">B25</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.8" evidence="11"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000032">
        <property type="protein sequence ID" value="OPD63531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0254"/>
    <dbReference type="EnsemblBacteria" id="ALN55613">
        <property type="protein sequence ID" value="ALN55613"/>
        <property type="gene ID" value="GLE_0254"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63531">
        <property type="protein sequence ID" value="OPD63531"/>
        <property type="gene ID" value="BV903_12970"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0254"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.256"/>
    <dbReference type="OMA" id="PGAMVIY"/>
    <dbReference type="OrthoDB" id="256504at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004615">
        <property type="term" value="F:phosphomannomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_I" evidence="8">
        <location>
            <begin position="320"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="9">
        <location>
            <begin position="467"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="10">
        <location>
            <begin position="569"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="7">
        <location>
            <begin position="699"/>
            <end position="761"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN55613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OPD63531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="772" mass="81802" checksum="4BBE76D4A5F24635" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB58</accession>
    <name>A0A0S2DB58_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fucose-binding lectin II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_02775</name>
        <name evidence="1" type="ORF">GLE_0396</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946002.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55754">
        <property type="protein sequence ID" value="ALN55754"/>
        <property type="gene ID" value="GLE_0396"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0396"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.393"/>
    <dbReference type="OrthoDB" id="1691259at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.400">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036684">
        <property type="entry name" value="Ca_lectin_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0430">Lectin</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="141" mass="15020" checksum="C0FE033B500D0026" modified="2016-02-17" version="1">MAGIQWSAPQSLAYIPTGKLVTFTAMHQAEYTQYVQIIDANNRPISFYCLDGSQATFPISGSGVNVGFLQNGAGRFTMAAGLQVQFGSSGSKVPLVSAGNPVQFFINGSVFGGGTLYVTEDGGDMDYNDTSFVIQWYAYVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB98</accession>
    <name>A0A0S2DB98_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Hydrolase, alpha/beta hydrolase fold family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_02850</name>
        <name evidence="2" type="ORF">GLE_0412</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946016.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55770">
        <property type="protein sequence ID" value="ALN55770"/>
        <property type="gene ID" value="GLE_0412"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0412"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.409"/>
    <dbReference type="OMA" id="LTNCETH"/>
    <dbReference type="OrthoDB" id="1119700at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="69"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="344" mass="37771" checksum="5CF233BF9F8E1F22" modified="2016-02-17" version="1">MKRRALLSACAAAAGWALLPGCRTIGGDGSGGERAPRLDAAAFHASRRLVPTRFGRIACVERGSGPAALFVHGFPLNGFQWRGALERLSPQRRCIAPDLLGLGYSEASARQDLSPQAQSDMLAALLDELAVSEVDLIANDSGGTVAQLLLVRHPGRVRSLILTNCDVHENSPPPQMRNSIQKARDGVYDQKLERHLQDRAYARSAQGIGGSAYTDPASFSDEAIEYYLAPLLASPLRRQQLNRHLAAFEPNPLLAIEPALRRCRVPTRMLWGDADPLFPMRWAQWLDRTLPGSRGVRRVEGGRLFWPEERPDLLADEARALWGLGQPSEARTRANEPFPRIPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBH1</accession>
    <name>A0A0S2DBH1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0516</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946091.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55874">
        <property type="protein sequence ID" value="ALN55874"/>
        <property type="gene ID" value="GLE_0516"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0516"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.511"/>
    <dbReference type="OMA" id="CTARFEI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="130" mass="13665" checksum="244C4EBB623BD4E2" modified="2016-02-17" version="1">MTAAVSMVLFPAAAFDLDWAHATLSAQGLEVAAAAQGLQVRWDEDGPVLRIAFVHGAQVAREAAAIAAGGGYADALRGCDARFEIAIDDLDEALDEMNTLIEVQTTLQEGTGGFLFNDWNGELSPNPSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBZ0</accession>
    <name>A0A0S2DBZ0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0674</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56032">
        <property type="protein sequence ID" value="ALN56032"/>
        <property type="gene ID" value="GLE_0674"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0674"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="81" mass="8360" checksum="62F978564B87C82B" modified="2016-02-17" version="1">MRENPIVACAGGCANRTGAGAVLKAYAAQPVRRRRVRTPQYCRRRPVGEAARAGVDRSASGRAAAVAQRLPASSVRGGAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC28</accession>
    <name>A0A0S2DC28_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">6-carboxy-5,6,7,8-tetrahydropterin synthase</fullName>
            <ecNumber evidence="8">4.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">queD</name>
        <name evidence="11" type="ORF">GLE_0720</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7,8-dihydroneopterin 3'-triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + 2 H(+) + triphosphate</text>
            <dbReference type="Rhea" id="RHEA:27966"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="ChEBI" id="CHEBI:61032"/>
            <dbReference type="EC" id="4.1.2.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8 10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8 10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the PTPS family. QueD subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.-.-.-" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0720"/>
    <dbReference type="EnsemblBacteria" id="ALN56078">
        <property type="protein sequence ID" value="ALN56078"/>
        <property type="gene ID" value="GLE_0720"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0720"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.708"/>
    <dbReference type="OMA" id="KCEKLHG"/>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070497">
        <property type="term" value="F:6-carboxy-5,6,7,8-tetrahydropterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007115">
        <property type="entry name" value="6-PTP_synth/QueD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038418">
        <property type="entry name" value="6-PTP_synth/QueD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12589">
        <property type="entry name" value="PTHR12589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01242">
        <property type="entry name" value="PTPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006113">
        <property type="entry name" value="PTP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03367">
        <property type="entry name" value="queuosine_QueD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 10" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="27"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="9">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="9">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR006113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR006113-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006113-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN56078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="121" mass="13868" checksum="73444F6BFE037AE6" modified="2016-02-17" version="1">MPAIDIFKVFTLEAAHRLPNVPEGHKCARLHGHSFRVEVHLRGDIGEHSGWLMDYADVKKAFQPIHDRLDHHYLNDIEGLDNPTSERLAVWIWEQLKPALPLLSEIVVHETCTAGSRYRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC88</accession>
    <name>A0A0S2DC88_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">1-acyl-sn-glycerol-3-phosphate acyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_04460</name>
        <name evidence="2" type="ORF">GLE_0757</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946277.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0757"/>
    <dbReference type="EnsemblBacteria" id="ALN56115">
        <property type="protein sequence ID" value="ALN56115"/>
        <property type="gene ID" value="GLE_0757"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0757"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.745"/>
    <dbReference type="OMA" id="FANHTSH"/>
    <dbReference type="OrthoDB" id="1756450at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="1">
        <location>
            <begin position="33"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="210" mass="23508" checksum="19A0D2534F0874EA" modified="2016-02-17" version="1">MISHLLAAGFSSAIRLLTGARALWRCSPSADHRVYYGNHVSHGDFVMIWSALPPSLRREVRPVAGADYWQRDALRRYLIREVFNGVLIERDAAARKYDPIDVLCEAVDGGQSLILFPEGTRNQSDEPLLPFKSGLYHLARRRPELEFVPVWIDNLARVMPKGKILPLPLLCTATFGDTLRLGADEDKDAFLQRARDALLALSEQGNGGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCE9</accession>
    <name>A0A0S2DCE9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ATP synthase subunit alpha</fullName>
            <ecNumber evidence="14">7.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">ATP synthase F1 sector subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">F-ATPase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14 18" type="primary">atpA</name>
        <name evidence="19" type="ORF">FE772_04120</name>
        <name evidence="18" type="ORF">GLE_0687</name>
    </gene>
    <organism evidence="18 20">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="18 20" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 20">C3</strain>
        </source>
    </reference>
    <reference evidence="19 21" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 21">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 14">Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cell membrane</location>
            <topology evidence="14">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="14"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946216.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0687"/>
    <dbReference type="EnsemblBacteria" id="ALN56045">
        <property type="protein sequence ID" value="ALN56045"/>
        <property type="gene ID" value="GLE_0687"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0687"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.675"/>
    <dbReference type="OMA" id="LQAPGVM"/>
    <dbReference type="OrthoDB" id="837522at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18113">
        <property type="entry name" value="ATP-synt_F1_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01132">
        <property type="entry name" value="F1_ATPase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01346">
        <property type="entry name" value="ATP_synth_alpha_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000793">
        <property type="entry name" value="ATP_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038376">
        <property type="entry name" value="ATP_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033732">
        <property type="entry name" value="ATP_synth_F1_a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005294">
        <property type="entry name" value="ATP_synth_F1_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00306">
        <property type="entry name" value="ATP-synt_ab_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="SSF50615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00962">
        <property type="entry name" value="atpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="6 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 14" id="KW-0139">CF(1)</keyword>
    <keyword evidence="5 14" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 14" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP-synt_ab_N" evidence="17">
        <location>
            <begin position="32"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab" evidence="15">
        <location>
            <begin position="152"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab_C" evidence="16">
        <location>
            <begin position="385"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="172"/>
            <end position="179"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Required for activity" evidence="14">
        <location>
            <position position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00026013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ALN56045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="QCW24978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="516" mass="55607" checksum="759AF45A3C6D3B8E" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCU0</accession>
    <name>A0A0S2DCU0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_05525</name>
        <name evidence="2" type="ORF">GLE_0984</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946439.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56342">
        <property type="protein sequence ID" value="ALN56342"/>
        <property type="gene ID" value="GLE_0984"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0984"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.972"/>
    <dbReference type="OrthoDB" id="2094697at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="317" mass="34929" checksum="2606DCDB76012DEF" modified="2016-02-17" version="1">MKLRISGQEQEQGQEPQQAQAAPEQAGPSYDVRALNEHLGDRHARQQQPAGPEQGPALDWQRNGPGQWAEPGAQAPQPAQADLTPEQRMQRYREVVQGAMDAYRGEVATERENAASRRAAHPEGPQVNAERAREQEKHWSGIESAASQLNALVKNPIPAAAEARFRPLIDDRVDNMVQLAATPQRPDVERIRNQDDVRGRQPHQELGKDGDGRYHLTDPSTGQRAAANGDFVFVIPVSNPSQVWIGERATGGHTAISRGGDVYYAGEVSFRDGEITRWSNDSGHYRPNADLHRQVGSASIATLEGLLPRDKFQPYNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCW3</accession>
    <name>A0A0S2DCW3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_05670</name>
        <name evidence="1" type="ORF">GLE_1015</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946461.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56373">
        <property type="protein sequence ID" value="ALN56373"/>
        <property type="gene ID" value="GLE_1015"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1015"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1003"/>
    <dbReference type="OMA" id="ANHANYL"/>
    <dbReference type="OrthoDB" id="1956887at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="133" mass="14833" checksum="46BE64E5D8C1F98A" modified="2016-02-17" version="1">MQSKTDANAAWALGLLDWNRAHLTHDSDLSEAAVGERFADRLVVKANGRTYEADRRAYKEFLDGFRRTIAAIDYQVHETVANEASAVLVMSARVDRLDGSVDRFEAMLLLKFDGSGRVELWQEVYVKAEGPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCY4</accession>
    <name>A0A0S2DCY4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Integrase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_1027</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the transposition of the insertion element.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transposase IS30 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56385">
        <property type="protein sequence ID" value="ALN56385"/>
        <property type="gene ID" value="GLE_1027"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1027"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1015"/>
    <dbReference type="OMA" id="EMVAHET"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001598">
        <property type="entry name" value="Transposase_IS30_CS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01043">
        <property type="entry name" value="TRANSPOSASE_IS30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="4">
        <location>
            <begin position="61"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="27"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="226" mass="25552" checksum="C465DAB56D7AE41C" modified="2016-02-17" version="1">MSHETIYTAIYAMPRGELRRQVTRLLRQGRKSGRRTRQGSDARGHLPDLPNIRLRPPAAHERLMPGHWEGDLIVGAHNRSAIGVLVCRRTLYVKLVKLADATAHTVLEAFSSAFEGVPESLKKTLTYDQGKEMASHRQLSERTGLAIYFADPHSPWQRGTCENTNGLLRQYFPKGTDLSVHSAQRLKEVAWEMNNRPRRSLGRRSPVEVLYEELKNPRAQGDALGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD74</accession>
    <name>A0A0S2DD74_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA polymerase sigma-E factor</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">RNA polymerase subunit sigma-24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BV903_04030</name>
        <name evidence="5" type="ORF">GLE_1100</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">B25</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000007">
        <property type="protein sequence ID" value="OPD65267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1100"/>
    <dbReference type="EnsemblBacteria" id="ALN56458">
        <property type="protein sequence ID" value="ALN56458"/>
        <property type="gene ID" value="GLE_1100"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65267">
        <property type="protein sequence ID" value="OPD65267"/>
        <property type="gene ID" value="BV903_04030"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1100"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1087"/>
    <dbReference type="OMA" id="TWMYRIV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="3">
        <location>
            <begin position="39"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="4">
        <location>
            <begin position="135"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD65267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="195" mass="21144" checksum="1FEFC816773FD72C" modified="2016-02-17" version="1">MLTAVNDTMPDAAPALDADADQELVAQAAAGGVAAFEALYRRHASRVHGVIARLVGYHGARAEDLTQEAFVRAWQALPNFRFESAFGTWLHRLAVNTALMELRGRRGRPFEDSDEDVFDTIGSADSAGHVTALSMDLERAVASLPPRARAVLVLYDVEGWKHEEIAAELGMAVGSSKAQLHRARSLLRARLGEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDC9</accession>
    <name>A0A0S2DDC9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/beta hydrolase fold</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Homoserine O-succinyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.46</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_06150</name>
        <name evidence="4" type="ORF">GLE_1122</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.46" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1122"/>
    <dbReference type="EnsemblBacteria" id="ALN56480">
        <property type="protein sequence ID" value="ALN56480"/>
        <property type="gene ID" value="GLE_1122"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1122"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1108"/>
    <dbReference type="OMA" id="QLQCAEQ"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008899">
        <property type="term" value="F:homoserine O-succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008220">
        <property type="entry name" value="HAT_MetX-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268">
        <property type="entry name" value="PTHR32268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000443">
        <property type="entry name" value="Homoser_Ac_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="96"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000443-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="355" mass="38516" checksum="563FC094DEAED864" modified="2016-02-17" version="1">MSFAPSIDSRSAASVERSDSYASYAASAAAFERAPTPRAVRGEIAIELELRHAGRRALRLRYEIQGDRALPAVFVAGGISAHRHLAPSREFAEAGWWESQVGAGRSLDPARHCLVSFDWVGADGALDVAIDPADQADAVAALLDALKIARLQAFVGYSYGAMVGLQFAARHPQRIESLVSISGTHRAHPYAAAWRALQRRAVALGALQCDEAQGLALARELAVLSYRTPEEFAERFGAAQVVDGRVRVDAEDYLDHCGNKYVARTSPTAFLRLSESIDLQQVDPASIRIPVTVVAVGEDRLIPLGDNYELVERLRGETRLRVLRSIYGHDACLKEQSQIDTILREALADCTSAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDN9</accession>
    <name>A0A0S2DDN9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cell wall hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_20855</name>
        <name evidence="5" type="ORF">D9T17_20720</name>
        <name evidence="4" type="ORF">FE772_06955</name>
        <name evidence="2" type="ORF">GLE_1292</name>
    </gene>
    <organism evidence="2 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">C3</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 9" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000064">
        <property type="protein sequence ID" value="OPD62011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000050">
        <property type="protein sequence ID" value="ROU05063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946665.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000050.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1292"/>
    <dbReference type="EnsemblBacteria" id="ALN56649">
        <property type="protein sequence ID" value="ALN56649"/>
        <property type="gene ID" value="GLE_1292"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62011">
        <property type="protein sequence ID" value="OPD62011"/>
        <property type="gene ID" value="BV903_20855"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1292"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1275"/>
    <dbReference type="OMA" id="HTFYKVQ"/>
    <dbReference type="OrthoDB" id="682655at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011105">
        <property type="entry name" value="Cell_wall_hydrolase_SleB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042047">
        <property type="entry name" value="SleB_dom1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07486">
        <property type="entry name" value="Hydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_2" evidence="1">
        <location>
            <begin position="34"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU05063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="152" mass="16597" checksum="D8AF7A23DAF4354C" modified="2016-02-17" version="1">MKLAWILWLASVLPPQTADSLCLSTTVYLEARDQSQRGQQAVAEVALRRRDSGIWGDTVCEVVTANKQFAPTLVSPGTRLSNSEAWAESVNVALAAERNWALPAGQRKEIVPGASHFAAHAIASPSWRNAYQVATIGDHTFYKVQALKPRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDQ2</accession>
    <name>A0A0S2DDQ2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Excinuclease ABC, C subunit-like</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">GIY-YIG nuclease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_07365</name>
        <name evidence="2" type="ORF">GLE_1390</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946741.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1390"/>
    <dbReference type="EnsemblBacteria" id="ALN56747">
        <property type="protein sequence ID" value="ALN56747"/>
        <property type="gene ID" value="GLE_1390"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1390"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1372"/>
    <dbReference type="OMA" id="RLYTGIT"/>
    <dbReference type="OrthoDB" id="2077602at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="90" mass="9773" checksum="F5D304850BE83AAC" modified="2016-02-17" version="1">MPWYVYLIECTDGSLYTGIAVDVERRYAQHAAGKGARYTRAHPPARLLARFEHPDRGAALRAEYAIKQLTAAAKRALCAQAPVAAESATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDX7</accession>
    <name>A0A0S2DDX7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ATP-dependent RNA helicase DbpA</fullName>
            <ecNumber evidence="11">3.6.4.13</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="10">Dead/deah box helicase domain/helicase conserved domain/dbpa rna binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">dbpA</name>
        <name evidence="11" type="ORF">FE772_07415</name>
        <name evidence="10" type="ORF">GLE_1400</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="11"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946749.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1400"/>
    <dbReference type="EnsemblBacteria" id="ALN56757">
        <property type="protein sequence ID" value="ALN56757"/>
        <property type="gene ID" value="GLE_1400"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1400"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1382"/>
    <dbReference type="OMA" id="FGCQALV"/>
    <dbReference type="OrthoDB" id="626183at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005580">
        <property type="entry name" value="DbpA/CsdA_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03880">
        <property type="entry name" value="DbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="9">
        <location>
            <begin position="13"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="44"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="225"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="13"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN56757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW25520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="468" mass="50168" checksum="A725042D9EC4B53A" modified="2016-02-17" version="1">MEPQTPTADAAPAAFDTLPLAPALLQGVAALGYSAMTPVQARALPAILDGRDVIAQAPTGSGKTAAFGLGLLQRLDPAQIRTQALVLCPTRELADQVGQQLRKLAFAIANLKVSVLCGGMPLGPQLASLEHAPHIAVGTPGRLQELLRHGALKLDGLRTLVFDEADRMFDMGFEEAVREIVRKTPKNRQGLLFSATFPDAIRELGRNALRDPVEVTVEGESSAPRIDQYFYEAEAGRKTPLLGALLLEYRPESCVVFCNMRKDTEEVVGSLEHYGFTALALHGEMEQRDRDEVLVRFANRSCNVLVASDVAARGLDVEDLGAVVNYDLPTDPDVYVHRIGRTGRAGRGGVALSLCGPRETARAEQIAQRMGAPLQWRSAQPLGGKARNAPAAPMATLRIDAGKTDKLRPGDILGALTGEAGLKAEAVGKINVFATRSYVAVARGQAAAALARLREGKIKGRKFRVNRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE40</accession>
    <name>A0A0S2DE40_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_16495</name>
        <name evidence="4" type="ORF">FE772_06595</name>
        <name evidence="2" type="ORF">GLE_1216</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000043">
        <property type="protein sequence ID" value="OPD62877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946605.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1216"/>
    <dbReference type="EnsemblBacteria" id="ALN56573">
        <property type="protein sequence ID" value="ALN56573"/>
        <property type="gene ID" value="GLE_1216"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62877">
        <property type="protein sequence ID" value="OPD62877"/>
        <property type="gene ID" value="BV903_16495"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1216"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1201"/>
    <dbReference type="OrthoDB" id="1976167at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="140" mass="14465" checksum="FE02096BBC829670" modified="2016-02-17" version="1">MSHPAPPAVAFGAEDESHLKLLSIFYYVLAALGALALLMAVGITVLLFGYLGAGGAGHDGSVAAGDLTVLIVVMALSVALSLASGILQFMTARRLSQRRGRGLCQFTAAITCLSFPLGTLLGVFTFIVLARPQVRAAFGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEB4</accession>
    <name>A0A0S2DEB4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1609</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56966">
        <property type="protein sequence ID" value="ALN56966"/>
        <property type="gene ID" value="GLE_1609"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1609"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1589"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="146" mass="15364" checksum="44F75FF17DBA1582" modified="2016-02-17" version="1">MAAQVGAGSSRERVLRGRYDAALAGRPRRARCPGCTPTRRIVAAFTASRTRRGFHQEQHAMATRIDPRQFVIVASYVSPGVAAGAGGFVIVGGKLKKVPPRGLRQLQAVYQMLEAADGVGDAKIAAQLQQSAIDLAGVAVGQKAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DED9</accession>
    <name>A0A0S2DED9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1578</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1578"/>
    <dbReference type="EnsemblBacteria" id="ALN56935">
        <property type="protein sequence ID" value="ALN56935"/>
        <property type="gene ID" value="GLE_1578"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1578"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1558"/>
    <dbReference type="OMA" id="MMIPIIF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="2">
        <location>
            <begin position="193"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="390" mass="42548" checksum="40DEA1594E8EDCAD" modified="2016-02-17" version="1">MRFAGLFTWGVAGCWLVIMWLEPEAATSLPGGSEHTFFLLILRWVAIHLAFGAVYWWASRGLGQRRPGPADHALLLVLTACAIGVGYFSNSGIGSILLMVVAGLLPWLLPLRVGVAWLVLSNLSIIPVFVIAIGQPLLVAIVQSVAYAGFSSLVFVSSLVAMQQAQAREDQRRLNAELRATRALLAESARINERTRISRELHDLLGHHLTALSLNLEVAGHLSEGRVKEHVQQAHTLARLLLTDVREAVSQLRENGAIDLSLALRPLAENVPALDIRMDIETPLTLDDPERAHVLLRCAQEIITNAVRHAGAQHLWIDVRRNDGHIVMSARDDGRGADHLIAGNGLRGMRERLVQHGGQLRIETRAEAGFSLRLTLPATAAAMGREGALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEE4</accession>
    <name>A0A0S2DEE4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Septum site-determining protein MinD</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Cell division inhibitor MinD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">minD</name>
        <name evidence="10" type="ORF">FE772_08200</name>
        <name evidence="9" type="ORF">GLE_1575</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with MinC and FtsZ.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ParA family. MinD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946888.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1575"/>
    <dbReference type="EnsemblBacteria" id="ALN56932">
        <property type="protein sequence ID" value="ALN56932"/>
        <property type="gene ID" value="GLE_1575"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1575"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1555"/>
    <dbReference type="OMA" id="CESAKAY"/>
    <dbReference type="OrthoDB" id="1631847at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010223">
        <property type="entry name" value="MinD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025501">
        <property type="entry name" value="MinD_FleN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003092">
        <property type="entry name" value="MinD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01968">
        <property type="entry name" value="minD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiA" evidence="8">
        <location>
            <begin position="5"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW25653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="269" mass="29175" checksum="1C43611FADC603E4" modified="2016-02-17" version="1">MTEIIVVTSGKGGVGKTTTSASLSCGLARRGHKVAVIDFDVGLRNLDLIMGCERRVVYDFVNVVNGEAALKQALIKDKRFENLFILAASQTRDKDALTKEGVQKVLEDLAAEGFDYIVCDSPAGIEKGAFLAMYFADQAVVVVNPEVSSVRDSDRILGLLSSKTRRAENGERVKEHLLLTRYSPKRVETGEMLSIGDVEEILGLKTVGVIPESGDVLNASNKGEPVILETESDAAQAYDDAVARLLGDTRPMRFTQVEKKGFFSKIFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEG8</accession>
    <name>A0A0S2DEG8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">UDP-2,3-diacylglucosamine hydrolase</fullName>
            <ecNumber evidence="9">3.6.1.54</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">UDP-2,3-diacylglucosamine diphosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 11" type="primary">lpxH</name>
        <name evidence="12" type="ORF">FE772_07165</name>
        <name evidence="11" type="ORF">GLE_1346</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>H2O + UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine = 2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosaminyl 1-phosphate + 2 H(+) + UMP</text>
            <dbReference type="Rhea" id="RHEA:25213"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:57957"/>
            <dbReference type="ChEBI" id="CHEBI:78847"/>
            <dbReference type="EC" id="3.6.1.54"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="9">Binds 2 Mn(2+) ions per subunit in a binuclear metal center.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 4/6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the LpxH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.54" evidence="9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946705.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1346"/>
    <dbReference type="EnsemblBacteria" id="ALN56703">
        <property type="protein sequence ID" value="ALN56703"/>
        <property type="gene ID" value="GLE_1346"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1346"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1328"/>
    <dbReference type="OMA" id="FDFWFEY"/>
    <dbReference type="OrthoDB" id="1690667at2"/>
    <dbReference type="UniPathway" id="UPA00359">
        <property type="reaction ID" value="UER00480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019897">
        <property type="term" value="C:extrinsic component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008758">
        <property type="term" value="F:UDP-2,3-diacylglucosamine hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00575">
        <property type="entry name" value="LpxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043461">
        <property type="entry name" value="LpxH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010138">
        <property type="entry name" value="UDP-diacylglucosamine_Hdrlase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34990">
        <property type="entry name" value="PTHR34990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34990:SF1">
        <property type="entry name" value="PTHR34990:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01854">
        <property type="entry name" value="lipid_A_lpxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="2 9" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 9" id="KW-0464">Manganese</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="10">
        <location>
            <begin position="1"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="79"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN56703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW25477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="244" mass="27054" checksum="EA94085EAA296FD5" modified="2016-02-17" version="1">MTTLFISDLHLDAERPQITELFGRFVRDEARGADALYILGDLFEAWVGDDDPAETGAFVAAELKALADSGVPVFFIRGNRDFLLGREYADRAGMRILPDPAVIVLYGRPVLIGHGDLLCTDDVAYQQFRAQTRHPRWQAQFLAQPLAARLAFAQQARAASKAHQAGLKDDGRMETITDVAPATVEETFVRYGVDTMIHGHTHRPAIHELDAGGRACKRVVLGDWYEQGSVLRVDRDGLRLQALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEJ9</accession>
    <name>A0A0S2DEJ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alkilphosphonate uptake protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Alkylphosphonate utilization operon protein PhnA</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Alkylphosphonate utilization protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">phnA</name>
        <name evidence="4" type="ORF">FE772_08515</name>
        <name evidence="2" type="ORF">GLE_1642</name>
        <name evidence="3" type="ORF">LEN_3323</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="journal article" date="2016" name="DNA Res." volume="0" first="0" last="0">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer, Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">M497-1</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="journal article" date="2017" name="DNA Res." volume="24" first="169" last="177">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
            <dbReference type="PubMed" id="28065880"/>
            <dbReference type="DOI" id=".1093/dnares/dsw055"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">M497-1</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP014940">
        <property type="protein sequence ID" value="BAV98810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_055903378.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1642"/>
    <dbReference type="EnsemblBacteria" id="ALN56999">
        <property type="protein sequence ID" value="ALN56999"/>
        <property type="gene ID" value="GLE_1642"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAV98810">
        <property type="protein sequence ID" value="BAV98810"/>
        <property type="gene ID" value="LEN_3323"/>
    </dbReference>
    <dbReference type="KEGG" id="lem:LEN_3323"/>
    <dbReference type="KEGG" id="lez:GLE_1642"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1621"/>
    <dbReference type="OMA" id="PGEIECN"/>
    <dbReference type="OrthoDB" id="1507972at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000218824">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004624">
        <property type="entry name" value="YjdM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013988">
        <property type="entry name" value="YjdM_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30305:SF3">
        <property type="entry name" value="PTHR30305:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03831">
        <property type="entry name" value="YjdM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YjdM" evidence="1">
        <location>
            <begin position="3"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAV98810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000218824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="70" mass="7675" checksum="F86DE2E454D8F39A" modified="2016-02-17" version="1">MIVKDSNGTALADGDSVLVIKDLKVKGTSVTLKRGTLCKNIRLTDDEELIECNVEKVKGLVLRTEFLKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEK5</accession>
    <name>A0A0S2DEK5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aspartate/glutamate leucyltransferase</fullName>
            <ecNumber evidence="4">2.3.2.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">bpt</name>
        <name evidence="8" type="ORF">FE772_08310</name>
        <name evidence="7" type="ORF">GLE_1597</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-leucyl-tRNA(Leu) + N-terminal L-aspartyl-[protein] = H(+) + N-terminal L-leucyl-L-aspartyl-[protein] + tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:50420"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="Rhea" id="RHEA-COMP:12669"/>
            <dbReference type="Rhea" id="RHEA-COMP:12674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64720"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:133042"/>
            <dbReference type="EC" id="2.3.2.29"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-leucyl-tRNA(Leu) + N-terminal L-glutamyl-[protein] = H(+) + N-terminal L-leucyl-L-glutamyl-[protein] + tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:50412"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="Rhea" id="RHEA-COMP:12664"/>
            <dbReference type="Rhea" id="RHEA-COMP:12668"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64721"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:133041"/>
            <dbReference type="EC" id="2.3.2.29"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the R-transferase family. Bpt subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.29" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946909.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1597"/>
    <dbReference type="EnsemblBacteria" id="ALN56954">
        <property type="protein sequence ID" value="ALN56954"/>
        <property type="gene ID" value="GLE_1597"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1597"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1577"/>
    <dbReference type="OMA" id="MVEDSHV"/>
    <dbReference type="OrthoDB" id="1675133at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004057">
        <property type="term" value="F:arginyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008914">
        <property type="term" value="F:leucyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071596">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process via the N-end rule pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00689">
        <property type="entry name" value="Bpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017138">
        <property type="entry name" value="Asp_Glu_LeuTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030700">
        <property type="entry name" value="N-end_Aminoacyl_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007472">
        <property type="entry name" value="N-end_Aminoacyl_Trfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007471">
        <property type="entry name" value="N-end_Aminoacyl_Trfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21367">
        <property type="entry name" value="PTHR21367"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04377">
        <property type="entry name" value="ATE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04376">
        <property type="entry name" value="ATE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037208">
        <property type="entry name" value="ATE_pro_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATE_N" evidence="5">
        <location>
            <begin position="21"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="ATE_C" evidence="6">
        <location>
            <begin position="111"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN56954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW28676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="245" mass="28629" checksum="AE31F3B4182FC740" modified="2016-02-17" version="1">MGTQPQQPDSDDLRLFHTGEHACGYWPERIARDLVLDPRDPRLREWYPHALGWGFRRSGDIVYRPHCSGCRACVAVRIPVDRFVPDRSQRRCLARNAQVEMRVHRAERTPEQLALYKRYLASRHSGGGMDGHGAIEFDQFLIGSWSENRFLELREAGHGRLLAVAVTDVVEDALSAVYTFYDPDLADRSLGTLAILRQIEWARRERRRHLYLGYWIAGHPKMDYKRRFRPLEAFDGRDWRVFTHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEX8</accession>
    <name>A0A0S2DEX8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal RNA large subunit methyltransferase E</fullName>
            <ecNumber evidence="4">2.1.1.166</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">23S rRNA Um2552 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">rRNA (uridine-2'-O-)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 8" type="primary">rrmJ</name>
        <name evidence="4" type="synonym">ftsJ</name>
        <name evidence="4 9" type="synonym">rlmE</name>
        <name evidence="9" type="ORF">FE772_07900</name>
        <name evidence="8" type="ORF">GLE_1506</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>S-adenosyl-L-methionine + uridine(2552) in 23S rRNA = 2'-O-methyluridine(2552) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42720"/>
            <dbReference type="Rhea" id="RHEA-COMP:10202"/>
            <dbReference type="Rhea" id="RHEA-COMP:10203"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74478"/>
            <dbReference type="EC" id="2.1.1.166"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.166" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946832.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1506"/>
    <dbReference type="EnsemblBacteria" id="ALN56863">
        <property type="protein sequence ID" value="ALN56863"/>
        <property type="gene ID" value="GLE_1506"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1506"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1487"/>
    <dbReference type="OMA" id="HRQTDHL"/>
    <dbReference type="OrthoDB" id="1798571at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008650">
        <property type="term" value="F:rRNA (uridine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01547">
        <property type="entry name" value="RNA_methyltr_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015507">
        <property type="entry name" value="rRNA-MeTfrase_E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005461">
        <property type="entry name" value="23S_rRNA_mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FtsJ" evidence="7">
        <location>
            <begin position="29"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4 5">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR005461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN56863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW25600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="215" mass="24220" checksum="49C83525C2F120BA" modified="2016-02-17" version="1">MATRSKSSQRWLKEHFSDPFVKKAKSEGLRSRAAYKLEELVERDRLLKPGMVVVDLGAAPGGWSQWVRQEMERLWPKQAGRIVALDILDMPGLAGVEFIHGDFREDAVLAQLESTLDGQVVDLVLSDMAPNMSGVDAVDLPRAMHLSELAMDFADRHLRVEGTFLIKLFQGVGFDEYVRELRRRYAKVSIRKPAASRKRSPEVYALAQGKRATPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEZ1</accession>
    <name>A0A0S2DEZ1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1854</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57206">
        <property type="protein sequence ID" value="ALN57206"/>
        <property type="gene ID" value="GLE_1854"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1854"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1825"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="66" mass="7113" checksum="E33C66E0517571C0" modified="2016-02-17" version="1">MRNHLSDHGYSANEGVRQRDGGERTLYRSAPTADGIVFVVSAQLAPAGGECIQEIRINANTPEDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF17</accession>
    <name>A0A0S2DF17_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamine cyclotransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Glutaminyl-peptide cyclotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_09150</name>
        <name evidence="2" type="ORF">GLE_1778</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947043.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1778"/>
    <dbReference type="EnsemblBacteria" id="ALN57132">
        <property type="protein sequence ID" value="ALN57132"/>
        <property type="gene ID" value="GLE_1778"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1778"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1752"/>
    <dbReference type="OMA" id="FVTGKNW"/>
    <dbReference type="OrthoDB" id="966287at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016603">
        <property type="term" value="F:glutaminyl-peptide cyclotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017186">
        <property type="term" value="P:peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007788">
        <property type="entry name" value="QCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31270">
        <property type="entry name" value="PTHR31270"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05096">
        <property type="entry name" value="Glu_cyclase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="SSF50969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242298" evidence="1">
        <location>
            <begin position="30"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="273" mass="29932" checksum="6FFBD9ADE392FB5A" modified="2016-02-17" version="1">MPQRRPSPRPLAVAAFSAVLAAACAPSPAAPRTDAPVYSYKVVARYPHDSLAFTQGLIWKDGHLYESTGLNGRSSLRKVKLENGQVLQRRDLPAEVFGEGLTDRGEQLLMLTWTNGSGYVFNRGDFSPAGTFAYAGEGWGLTRSADTVYMSDGSAQLRLLDPATLRERSRIRVTDNGRAVDQLNELEWVKGEIYANVWQTDLIARIDPKTGQVRGWIDLSGLLQGHGTSVRGSDVLNGIAYDAKGDRLFVTGKLWPNLFQIELVPPAKPAPKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFB2</accession>
    <name>A0A0S2DFB2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57007">
        <property type="protein sequence ID" value="ALN57007"/>
        <property type="gene ID" value="GLE_1650"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1650"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1629"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="155" mass="16629" checksum="35541A76F6487C79" modified="2016-02-17" version="1">MAARPAAQPAAQQRHAPRPGRHQDERIHFLDHAIEGIAVAVASIPRTPPLPARRDGGETGASHWPDRSPSPQDRPRRTTPNRRPHAAALPSRCNLPAKLRGCADGADRARNAAEIGASHASCRPDWSIPADRAHPADSTGSTMPPVPCHGHVIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFD2</accession>
    <name>A0A0S2DFD2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_1850</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947095.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1850"/>
    <dbReference type="EnsemblBacteria" id="ALN57202">
        <property type="protein sequence ID" value="ALN57202"/>
        <property type="gene ID" value="GLE_1850"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1850"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1821"/>
    <dbReference type="OMA" id="IRHKCAD"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0274">FAD</keyword>
    <keyword evidence="2 4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="6">
        <location>
            <begin position="123"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="5">
        <location>
            <begin position="229"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="396" mass="42692" checksum="CD9C9BFA6646ED85" modified="2016-02-17" version="1">MTLQMESAFSDIAAFKDHLDAILARESTRRLVEDAEAAGLFPRGIVELLGREGIFAAKWQERPVPALEHTLALSERFGRLGAGGIASAVTLHDSAIAMLRRFGRSQALRDVADQAIAGRAVLCISATEAGAGSDMLGLSSTAVREEGGYRLRGHKKMASPSPVADYIVLALRGIDESHAGRDDLALFLVPTSQLRVGKAFETVGARSISTAPVFFDTWVPAEMMIARPGTGLAVLSWALAQERFAMAAQILGACHLALGVTVARMKRRKTFGVALFDHQALRLRIADLQARVDMMRLALNGLIANAAGFNVRSCSAAKVTAVRLGCEVMSECMHIFGSAGVLETESPLGRWWRDVKMARIGGGTDEMLWEIVAAGLEPDYASYDQMVNEWQPEPLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFH7</accession>
    <name>A0A0S2DFH7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase, S41 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_2048</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947242.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57398">
        <property type="protein sequence ID" value="ALN57398"/>
        <property type="gene ID" value="GLE_2048"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2048"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2013"/>
    <dbReference type="OMA" id="SGTNWEG"/>
    <dbReference type="OrthoDB" id="1646508at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595057" evidence="2">
        <location>
            <begin position="32"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="TSPc" evidence="3">
        <location>
            <begin position="129"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="446" mass="48133" checksum="6DD5E5BECFC6272C" modified="2016-02-17" version="1">MRQSSRPPRLGAWRRRAATLCLIALCAPAVAAPPAAPAGPRAIVAQVADAIDRNFYDPQRAARLAAQLREEAGAGRYDADTDPRDLATALSRRLRPEDNHFRVEWRDPALAAAAPRGPGPRPSADAADASRRRNYGLRAVETLAGNVGYLDLRELPDLDFDDPADPARRALDAALALLAERDAVIVDLRHNGGGSPASVGYLTSAFTPRGAPIYNRFRARLDGQTRSFDEAPLQWYPQPRLDVPLYVLTSARTGSAAEALAYTLQAARRATVIGEASAGAANPGGEFPLADGYRVFVSTGSPTNPITGGNWEGRGVQPDIATAAAQALDTARLRALERIVAARQDGPAALDARWTLEALRAQAAPAAFAAADYLGEYERLRIEDDNGRLLLRDGRRPPQPLTALQRDLFCLSDDPAVRLRFERGADGRVAALETLRSDGRSSRYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFJ8</accession>
    <name>A0A0S2DFJ8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)</fullName>
            <ecNumber evidence="6">1.17.7.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 7" type="primary">ispG</name>
        <name evidence="9" type="synonym">gcpE</name>
        <name evidence="8" type="ORF">BV903_13425</name>
        <name evidence="9" type="ORF">FE772_08990</name>
        <name evidence="7" type="ORF">GLE_1746</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + H2O + oxidized [flavodoxin] = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + reduced [flavodoxin]</text>
            <dbReference type="Rhea" id="RHEA:43604"/>
            <dbReference type="Rhea" id="RHEA-COMP:10622"/>
            <dbReference type="Rhea" id="RHEA-COMP:10623"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:58483"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="EC" id="1.17.7.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 5/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the IspG family.</text>
    </comment>
    <dbReference type="EC" id="1.17.7.3" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000034">
        <property type="protein sequence ID" value="OPD63427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947022.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1746"/>
    <dbReference type="EnsemblBacteria" id="ALN57101">
        <property type="protein sequence ID" value="ALN57101"/>
        <property type="gene ID" value="GLE_1746"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63427">
        <property type="protein sequence ID" value="OPD63427"/>
        <property type="gene ID" value="BV903_13425"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1746"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1722"/>
    <dbReference type="OMA" id="PTCGRTQ"/>
    <dbReference type="OrthoDB" id="665306at2"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00096"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046429">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00159">
        <property type="entry name" value="IspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016425">
        <property type="entry name" value="IspG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004588">
        <property type="entry name" value="IspG_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30454">
        <property type="entry name" value="PTHR30454"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04551">
        <property type="entry name" value="GcpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004640">
        <property type="entry name" value="IspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00612">
        <property type="entry name" value="ispG_gcpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 6" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="357"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="364"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD63427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW25781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="425" mass="44722" checksum="25059F32148DE9EF" modified="2016-02-17" version="1">MNSDAVLPCSVPDFGPLPRRLTRSVAIGGVQVGGGAPVVVQSMTNTDTADVASTTKQVAELWRAGSELVRVTVNTVEAAAAVPRIVDKLAMMGIEVPIIGDFHYNGHQLLSAEPACAEALGKYRINPGNVGFGKKKDSQFATLIEFAIKYAKPVRIGANWGSLDQALAAQLMDENANRAEPWDAGRVLREALIRSALDSAARAVELGLPAERIVLSAKVSGVQELIAVYRELASRGDYALHLGLTEAGIGSKGIVASSAALGVLLQEGIGDTIRISLTPEPGQARSNEVIVAQELLQTMGLRAFTPMVTACPGCGRTTSTFFQELAQTVQEHVRAKMPEWKITHPGAENLTLAVMGCVVNGPGESRHANIGISLPGTGEAPSAPVFEDGEKTVTLRGENIAREFVALIDGYVERRYGVPAAGGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFT9</accession>
    <name>A0A0S2DFT9_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_10470</name>
        <name evidence="2" type="ORF">GLE_2068</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947253.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57418">
        <property type="protein sequence ID" value="ALN57418"/>
        <property type="gene ID" value="GLE_2068"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2068"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2033"/>
    <dbReference type="OrthoDB" id="2147757at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242560" evidence="1">
        <location>
            <begin position="30"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="268" mass="26373" checksum="9B97542205E63FB1" modified="2016-02-17" version="1">MNQRISRSVRLGALACTLGLSFVATHASAQSAEVVSAGVKACALSGGVTVTVLGLNTTLPLPCTGQAQVVAPGSKENSALGLDVGLLGLVSVVKLDVARQRADYTNASGATALDGRSSVGGLSLVQNLVALEGATGALSCDSLTGSTVLQCQASADVANVRIAGGDVITVPSPLPKNFAVPVGGSLRLVVLGIPVEVPVGGALTLNRVDTAGVGSANVSVVHKPVQLTLGGSVSVGGLGLIGVQVEAAATPATINVRGRSPFTAIQVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG38</accession>
    <name>A0A0S2DG38_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Alpha-lytic protease prodomain/trypsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLE_1992</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947194.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1992"/>
    <dbReference type="EnsemblBacteria" id="ALN57342">
        <property type="protein sequence ID" value="ALN57342"/>
        <property type="gene ID" value="GLE_1992"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1992"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1959"/>
    <dbReference type="OMA" id="FYSGAQA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.50">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037295">
        <property type="entry name" value="Alpha-lytic_protease_prodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004236">
        <property type="entry name" value="Pept_S1_alpha_lytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001316">
        <property type="entry name" value="Pept_S1A_streptogrisin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035070">
        <property type="entry name" value="Streptogrisin_prodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02983">
        <property type="entry name" value="Pro_Al_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001134">
        <property type="entry name" value="Streptogrisin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00861">
        <property type="entry name" value="ALYTICPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54806">
        <property type="entry name" value="SSF54806"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 10" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594773" evidence="7">
        <location>
            <begin position="24"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="Pro_Al_protease" evidence="9">
        <location>
            <begin position="109"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="8">
        <location>
            <begin position="221"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="350"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="302"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="344"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001134-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001134-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN57342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="404" mass="41421" checksum="50BC8639D204F8C9" modified="2016-02-17" version="1">MRKFSMSVLAVAAAMVVSGSALAADDLAPALKSAMKRDLGLTDKQLAQYLTTERLATEQEKGLAKQLGDNYAGAWLERKADGSFGFVAASTSVSKAKTLTGIETRQARHSLKALDTAKGQLDNLLARSAKVPKGVYSWSVDLPSNSVVVGVAPGAQATGEDFVARSGLDASVVRFETMNEAPQRRIAIQGGRGMLRNPGDGYLYACSVGFPVTKGSTLGYATAGHCGDVGEIVYQENGQWNPGVRVGTFAASSMPSGTGTGPDRGWVKVDSNHTLSASVYGYGSGDVTVKGSTEAAVGAALCRSGRTSGWHCGAIRTKNMTVSYVDDNGNPDGTVTGLTRTSACAEGGDSGGSFITSVGQAQGVLSGGSGSCSGSQGNPGGGNSYYTPIKPILSAYGLTLKTNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG40</accession>
    <name>A0A0S2DG40_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57395">
        <property type="protein sequence ID" value="ALN57395"/>
        <property type="gene ID" value="GLE_2045"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2045"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2010"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="48" mass="5262" checksum="FAE79EF54657AE66" modified="2016-02-17" version="1">MAADSFRCDRARILPARHDRRRRARAPGAVARLPRAAPAGSIGRRANP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGE0</accession>
    <name>A0A0S2DGE0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">[Acyl-carrier-protein] S-malonyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">fabD</name>
        <name evidence="6" type="ORF">FE772_10635</name>
        <name evidence="5" type="ORF">GLE_2103</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>holo-[ACP] + malonyl-CoA = CoA + malonyl-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:41792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="EC" id="2.3.1.39"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.3.1.39" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2103"/>
    <dbReference type="EnsemblBacteria" id="ALN57453">
        <property type="protein sequence ID" value="ALN57453"/>
        <property type="gene ID" value="GLE_2103"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2103"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2067"/>
    <dbReference type="OMA" id="INQFGRN"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004314">
        <property type="term" value="F:[acyl-carrier-protein] S-malonyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004410">
        <property type="entry name" value="Malonyl_CoA-ACP_transAc_FabD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00128">
        <property type="entry name" value="fabD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_AT" evidence="4">
        <location>
            <begin position="6"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="PKS_AT" evidence="4">
        <location>
            <begin position="314"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW26055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="621" mass="68019" checksum="1D8F111185B1A4BF" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGN3</accession>
    <name>A0A0S2DGN3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Acetyltransf_6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947557.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2465"/>
    <dbReference type="EnsemblBacteria" id="ALN57814">
        <property type="protein sequence ID" value="ALN57814"/>
        <property type="gene ID" value="GLE_2465"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2465"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2427"/>
    <dbReference type="OMA" id="AGGYDYK"/>
    <dbReference type="OrthoDB" id="917865at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038740">
        <property type="entry name" value="BioF2-like_GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13480">
        <property type="entry name" value="Acetyltransf_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyltransf_6" evidence="1">
        <location>
            <begin position="178"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="382" mass="43273" checksum="E53E2D6FD371EF84" modified="2016-02-17" version="1">MNRADDYRVIVERELAPALARWREWERDGAAVGLFQREHWLRAWYATLGAQAGREPLLASIERRHDGRALLALPLVRERRGGLYCIAFADAGVSDYAAPICAPDCPADPVAVRAMFAALRRALPRADLWSLEKMPARVGRRDNPLLQLPGTRASALFGNPVTIGEDFDAWRFSREKTHRKELERSWRVFSRHPQASFERIEDPARALPVMDALEALQREAIQGKGWAYLLDEPGYREFYRELVARGLAGGETVLTALRAGDDIVAALLGLRRGEEYAMIRIGNAAGEWRNCSPGRLVIERTMAALHAQGVRRFDFTIGDYAYKRGFQPEREDLFDSTVALSWKGRPHSLRAGLRHRARAWLADRPELKRRLSALRSRTGDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGP2</accession>
    <name>A0A0S2DGP2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alanine dehydrogenase</fullName>
            <ecNumber evidence="2">1.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ald</name>
        <name evidence="7" type="ORF">FE772_11625</name>
        <name evidence="6" type="ORF">GLE_2317</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AlaDH/PNT family.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.1" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947445.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2317"/>
    <dbReference type="EnsemblBacteria" id="ALN57666">
        <property type="protein sequence ID" value="ALN57666"/>
        <property type="gene ID" value="GLE_2317"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2317"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2282"/>
    <dbReference type="OMA" id="HPYYHLY"/>
    <dbReference type="OrthoDB" id="673280at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000286">
        <property type="term" value="F:alanine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042853">
        <property type="term" value="P:L-alanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05305">
        <property type="entry name" value="L-AlaDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008141">
        <property type="entry name" value="Ala_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42795">
        <property type="entry name" value="PTHR42795"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01262">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01002">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlaDh_PNT_N" evidence="5">
        <location>
            <begin position="4"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="AlaDh_PNT_C" evidence="4">
        <location>
            <begin position="149"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW26222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="356" mass="37837" checksum="0CD779B5C12599C4" modified="2016-02-17" version="1">MRIGVPKETKTLEGRVALVPAAAGDLVKRGHEVWLEQDAGVKSGFKDADYTRLGVKIAPDAAGLYEKGELIVKVKEPIAGDLQHLRKDHLLFCYLHLAAEPALTKHLLDIGLTGVAFETVELPNGDLPLLAPMSVIAGKIGVQVGTHLLHQPMSGKGKLLGGLPSTERGKVVVFGAGKAGGASAALAAAAGANVTVFEMRQDRMDEMMRLGNNVTALYPYHDVVAREVASADLVIGAVLITGAKAPHVMTREMLRDMEDGSVVVDIAIDQGGCFETSRPTTWKEPTYVEEGVTHFCVTNMPGAVPQTSSQAICAAILPWVNKLAAGNDWRNNPALVRGINVEGGKIVHPALQDMKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGZ7</accession>
    <name>A0A0S2DGZ7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_11840</name>
        <name evidence="1" type="ORF">GLE_2365</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947482.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57714">
        <property type="protein sequence ID" value="ALN57714"/>
        <property type="gene ID" value="GLE_2365"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2365"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2326"/>
    <dbReference type="OMA" id="VALHCDD"/>
    <dbReference type="OrthoDB" id="2052268at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="63" mass="6848" checksum="BAE210BC90AA46F0" modified="2016-02-17" version="1">MTKLDKPLRRELDIDGKAYTLTVDPDGLKLTEKGRRNGVELRWSALASGDDAAAPTLPATLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH56</accession>
    <name>A0A0S2DH56_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2627</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947687.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57975">
        <property type="protein sequence ID" value="ALN57975"/>
        <property type="gene ID" value="GLE_2627"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2627"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2586"/>
    <dbReference type="OrthoDB" id="2179607at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595171" evidence="2">
        <location>
            <begin position="25"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="151" mass="15098" checksum="08AD1AA9835E4166" modified="2016-02-17" version="1">MSFLSLLLRLSLIVALSLNGYASAAMIASGGHAMGPHTAMAPAPAAGPAMADCHEGMDLPAMAHADGPMQHHGAAPGSMPDSTPHPGDPAAPQEGDCCGKFACQCDCLQAASIAHAVVPLPPRLDEIAPALPNAHAPPSGVLSLPIRPPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHA6</accession>
    <name>A0A0S2DHA6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-hydroxyanthranilate 3,4-dioxygenase</fullName>
            <ecNumber evidence="3">1.13.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">3-hydroxyanthranilate oxygenase</fullName>
            <shortName evidence="3">3-HAO</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">3-hydroxyanthranilic acid dioxygenase</fullName>
            <shortName evidence="3">HAD</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 4" type="primary">nbaC</name>
        <name evidence="5" type="ORF">BV903_18790</name>
        <name evidence="6" type="ORF">FE772_13400</name>
        <name evidence="4" type="ORF">GLE_2675</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">C3</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 3">Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>3-hydroxyanthranilate + O2 = (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde</text>
            <dbReference type="Rhea" id="RHEA:17953"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:36559"/>
            <dbReference type="ChEBI" id="CHEBI:77612"/>
            <dbReference type="EC" id="1.13.11.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="3">Binds 2 Fe(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the 3-HAO family.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.6" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000052">
        <property type="protein sequence ID" value="OPD62402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947725.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000052.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2675"/>
    <dbReference type="EnsemblBacteria" id="ALN58023">
        <property type="protein sequence ID" value="ALN58023"/>
        <property type="gene ID" value="GLE_2675"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62402">
        <property type="protein sequence ID" value="OPD62402"/>
        <property type="gene ID" value="BV903_18790"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2675"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2634"/>
    <dbReference type="OMA" id="NARKDYH"/>
    <dbReference type="OrthoDB" id="1591291at2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000334">
        <property type="term" value="F:3-hydroxyanthranilate 3,4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034354">
        <property type="term" value="P:'de novo' NAD biosynthetic process from tryptophan"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043420">
        <property type="term" value="P:anthranilate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019805">
        <property type="term" value="P:quinolinate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006569">
        <property type="term" value="P:tryptophan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06123">
        <property type="entry name" value="cupin_HAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00825">
        <property type="entry name" value="3_HAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010329">
        <property type="entry name" value="3hydroanth_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15497">
        <property type="entry name" value="PTHR15497"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06052">
        <property type="entry name" value="3-HAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03037">
        <property type="entry name" value="anthran_nbaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 3" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>O2</name>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD62402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW26508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="176" mass="20617" checksum="5AE2682CF120B921" modified="2016-02-17" version="1">MLPGPINLLSWIEEHRHLLKPPVGNKTIYVGDFIVMVVGGPNQRTDYHWDEGPEWFYQLEGEMVLRIQEDGAVRDIPIRAGEIFLLPARVPHSPQRMPDSVGLVIERKRLEHEDDGLMWFCERCNHKLYEEFFKLRNIETDFPPVFERFYSSREHRSCGQCGHLNPAPARYTMPDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHB3</accession>
    <name>A0A0S2DHB3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YcaO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2387</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947502.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57736">
        <property type="protein sequence ID" value="ALN57736"/>
        <property type="gene ID" value="GLE_2387"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2387"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2349"/>
    <dbReference type="OMA" id="NEWIERD"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003776">
        <property type="entry name" value="YcaO-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02624">
        <property type="entry name" value="YcaO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51664">
        <property type="entry name" value="YCAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YcaO" evidence="1">
        <location>
            <begin position="56"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="426" mass="46260" checksum="95B4CF28C412C8B0" modified="2016-02-17" version="1">MIPLERERSLDEAERAMRDFLDAQGWRAELERVGAPFAATICSLYDQADGRLLGNGFGKGEADPSRVGALFEAVEHLFTGKAPAHAVLSLRSGADCLADPLLAQLPVRAAFAQQPDRRLACRRYRAFAAGEPDAVLPLFLSYPTYLDWRAPQDDFDYASALRFGSNNGTAIGSSLAEAAVHAIGELIERDAWSLFLVGHFLGDPAAHGYLLPAQELPPALARRLGEAEAQLQREIVLIDATSDLGVPCIIATASDLRDGESIHPCGYGASLYPEHAAMRAITELVQALELPQLQPRLAGYSQAVLNALSAYPKLRDCAVFAIDRTRLRRRRWDFQAPAPLPPTALLELLTARLRARGIDLHYAINHHEPGHFCVINVVSLALERFFLVCSGIVMAPGQRGRDLLAGRLPVPGSAAVLDREAGLMPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHB4</accession>
    <name>A0A0S2DHB4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2491</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57840">
        <property type="protein sequence ID" value="ALN57840"/>
        <property type="gene ID" value="GLE_2491"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2491"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2454"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="104" mass="11505" checksum="192CD67345F00F24" modified="2016-02-17" version="1">MTPNGVACLQRRRRARRHRRIRARLRRAGGLRASGLRECGLRASGNSAIRGRFERQARRGDADEPQLSVPADAARLRRFLAVLTGAPCAPRPGAGETAVRLRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHB5</accession>
    <name>A0A0S2DHB5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AcrB multidrug efflux protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Multidrug efflux RND transporter permease subunit</fullName>
        </submittedName>
    </protein>
    <gene>
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                <person name="Fernandez C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Feng T."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
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                <person name="Shinya K."/>
                <person name="Ikeda H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer Lysobacter enzymogenes M497-1.</title>
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                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
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        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
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                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAV97521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROU05874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="SDW92710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000183696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000218824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="208" mass="24043" checksum="B73AD2B3F99FD560" modified="2016-02-17" version="1">MAKQTRQRILDAALIMFNAQGEPNVTTNHIADELEISPGNLYYHFRNKDDIIEQLFARFEERMDAALAAPQGRLPGLEDIWLQLHLVFECIWDYRFLYRDLVEILSRNRRLRMRFARILKRADEQAHLVMRGLSQAGVMRASGDELAATATNVLVIATFWLNYAAARGDKDEHAAIRDGIVQVMMLLSPFLRDAERMHLNTLIRAYLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIX8</accession>
    <name>A0A0S2DIX8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3145</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3145"/>
    <dbReference type="EnsemblBacteria" id="ALN58492">
        <property type="protein sequence ID" value="ALN58492"/>
        <property type="gene ID" value="GLE_3145"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3145"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3103"/>
    <dbReference type="OMA" id="PGHYVQF"/>
    <dbReference type="OrthoDB" id="520320at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="PTHR33361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595095" evidence="2">
        <location>
            <begin position="20"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="593"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="617" mass="66213" checksum="76331674E200E612" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ70</accession>
    <name>A0A0S2DJ70_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_15435</name>
        <name evidence="1" type="ORF">GLE_3098</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948040.1">
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58445">
        <property type="protein sequence ID" value="ALN58445"/>
        <property type="gene ID" value="GLE_3098"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3098"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3056"/>
    <dbReference type="OrthoDB" id="2045884at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="104" mass="10795" checksum="97B58FDFDE97716E" modified="2016-02-17" version="1">MAIASKGSRRIVVDGQAYRWAVRSRPTYTQGLGAPLAFAVQQVGAGEGQILHVVAAAARPDHWLGEPVATIAPAQVAAAIRLGLEAGWTPAAPGSAFELRLLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ71</accession>
    <name>A0A0S2DJ71_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF2169 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_16485</name>
        <name evidence="2" type="ORF">GLE_3333</name>
    </gene>
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        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW26999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948218.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3333"/>
    <dbReference type="EnsemblBacteria" id="ALN58679">
        <property type="protein sequence ID" value="ALN58679"/>
        <property type="gene ID" value="GLE_3333"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3333"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3283"/>
    <dbReference type="OMA" id="HWQARVG"/>
    <dbReference type="OrthoDB" id="994146at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018683">
        <property type="entry name" value="DUF2169"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09937">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2169" evidence="1">
        <location>
            <begin position="20"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="389" mass="42026" checksum="0E939D2533E2C41E" modified="2016-02-17" version="1">MELINGTGYDAAATEAVDHHGRAHLLVVLKASFALPDDDAGLPVALERQRGLLDTDLFEGEPGLSSPLIEADFCLRKSRCDVLFVGSAHAPGNAPATRLEVGLRVGSLDKRLIVHGDRRWTRRFGFGTPTPSRPQPFRSMPLTWSRAFGGTWAGDGEREEPTVCSRNPVGCGYAPRRRRSRILGTAVPNLEAPGRRVRKATGAYEPAGLGPLGRSWEPRAKLAGTYDQAWLDQVFPRLPQDFDEAFFQCAPPDQRIAFPRGGERLELLNLTPGGGRRAFCLPSDLDLPMAAILAPSRAIVTLSPVVDTLVVDGDNGSFDLVWRASLPLKRSLREIGTLGIGKVCKSWWKSRVFGTSDCGCGGKETDEEDLAPVTQALADVAAPGKEAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ75</accession>
    <name>A0A0S2DJ75_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3126</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58473">
        <property type="protein sequence ID" value="ALN58473"/>
        <property type="gene ID" value="GLE_3126"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3126"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3082"/>
    <dbReference type="OMA" id="IWTYDRV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014942">
        <property type="entry name" value="AbiEii"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08843">
        <property type="entry name" value="AbiEii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="315" mass="35897" checksum="CEFB81787BD54577" modified="2016-02-17" version="1">MERARAFAIAQRAAQRASRTIRYPDSTQLSGQGRPDLFDPALKHRSDAFRTGDPAFANDDDRERWYAARASVQAQMLRAIGRSAWRDRLVLRGSVLLHAYLGERARAPGDIDWVVLPDTLKPTDEAAREMLKDLARLLTERETIGPVRIHSDRVGHDDIWTYERAEGRRMTIVWSLDGLPEGQVQFDFVFCERLPQPPVPVGIPLSEGEPVSLLGASAELSLAWKLVWLQTDMWPQGKDLYDAVLLAEHCNMPLRLFVDAIRCNADHADWADDALPDIAAWEIEWDNFRAEYPWVEGDLEDWKRRLAAQLVFSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ89</accession>
    <name>A0A0S2DJ89_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3244</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58590">
        <property type="protein sequence ID" value="ALN58590"/>
        <property type="gene ID" value="GLE_3244"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3244"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3197"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="110" mass="11853" checksum="510D19FF5FAD0AE1" modified="2016-02-17" version="1">MPGGPPPGFFIARRVGDSARANTAPPTVIPAQTEIHFAFAFAFAVGSDATPSQAHAPQPRRACAWMRTRAMGQDVPYGAAPRPVLDLVALDPKKQGLFFGYFLCGLRQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK37</accession>
    <name>A0A0S2DK37_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RHS repeat-associated core domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Wall-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_17075</name>
        <name evidence="2" type="ORF">GLE_3464</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3464"/>
    <dbReference type="EnsemblBacteria" id="ALN58809">
        <property type="protein sequence ID" value="ALN58809"/>
        <property type="gene ID" value="GLE_3464"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3464"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3412"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="534" mass="58009" checksum="EB796A8D21105505" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK64</accession>
    <name>A0A0S2DK64_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3691</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59035">
        <property type="protein sequence ID" value="ALN59035"/>
        <property type="gene ID" value="GLE_3691"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3691"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3635"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="53" mass="5428" checksum="63BA42E49A0E6D19" modified="2016-02-17" version="1">MPAAGRRSGAFVESCVAVDRAAFASAGGRSPVLLAALRLRGVERDLLAMGTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKA1</accession>
    <name>A0A0S2DKA1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Prolyl oligopeptidase family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">S9 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_17890</name>
        <name evidence="5" type="ORF">GLE_3636</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S9C family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948433.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3636"/>
    <dbReference type="EnsemblBacteria" id="ALN58980">
        <property type="protein sequence ID" value="ALN58980"/>
        <property type="gene ID" value="GLE_3636"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3636"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3580"/>
    <dbReference type="OMA" id="YKHWDEW"/>
    <dbReference type="OrthoDB" id="821953at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242174" evidence="3">
        <location>
            <begin position="22"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="4">
        <location>
            <begin position="483"/>
            <end position="692"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW27223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="693" mass="75934" checksum="09C01361F93E6EB6" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKC0</accession>
    <name>A0A0S2DKC0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Peptidase, M48 family</fullName>
            <ecNumber evidence="10">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLE_3749</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948521.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3749"/>
    <dbReference type="EnsemblBacteria" id="ALN59093">
        <property type="protein sequence ID" value="ALN59093"/>
        <property type="gene ID" value="GLE_3749"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3749"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3693"/>
    <dbReference type="OMA" id="HEFAHYR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595354" evidence="8">
        <location>
            <begin position="44"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="9">
        <location>
            <begin position="85"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="411" mass="44579" checksum="A1723B458F291EC4" modified="2016-02-17" version="1">MSRAAVRPPRRSAPAPLRFVAPRLACLRLALACALAAPALASAAAPIEPIRPGERPGAGSTEAELWYGMDQAERDIKTAPALVRDPALNAYVQGVACKVAGEHCADLRVYIVDVPVFNASMAPNGAMLVFTGALLRMQDESELALVLGHEFAHYRQRHGLRGWTKAKSTSAVMASIAIIPSVVALAASLGGLASVSKFSRDMEREADQVGFDRVVGLGYDPQAGAQVWGRMLREEKSSKRSKPWPVFASHPNTAERLEDTAAAAKAHAGAPGEVGRDAYQAAMRPWLDRWLAAELSRRTYDTSIQVIADLREEAQRAGDQGNQGLYGYYLAEAYRRRGKNDDRQRSAQLLSEAVAHADAPPAAWREQAYALRERKDAAAAIDAFRRYLAAAPDAEERPFIEKTIAELETAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKH3</accession>
    <name>A0A0S2DKH3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_3438</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948295.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
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        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
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        <location>
            <begin position="197"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="449"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="227"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="589" mass="64761" checksum="B51BA392C5760771" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKN0</accession>
    <name>A0A0S2DKN0_LYSEN</name>
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        <recommendedName>
            <fullName evidence="9">GspH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
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        <name evidence="10" type="ORF">GLE_3581</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
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            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="GspH" evidence="9">
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            <begin position="42"/>
            <end position="148"/>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN58925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW27182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="178" mass="19948" checksum="83D4DE82896CAFDA" modified="2016-02-17" version="1">MRIKTLDAYEFVAAFLLANLLSLLVSPGPNASFHHLSARSFAQGLAGLYRQAGEHAARTGSPVLLCPVRWIYFHCRQQLDWSRGLMAFADHSRNRIFDPADELLRRELPLPSHLRLRALRGPVQVRFEAGSGRVLADTPWLLCDLRSVPRAWVLRRDSAGGFQVSDANAADTARCRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKN5</accession>
    <name>A0A0S2DKN5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_17055</name>
        <name evidence="1" type="ORF">GLE_3463</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58808">
        <property type="protein sequence ID" value="ALN58808"/>
        <property type="gene ID" value="GLE_3463"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3463"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3411"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="83" mass="9326" checksum="DD93B15D587958E8" modified="2016-02-17" version="1">MILYWFEFQPNSVPQCLDLGCGITARSQDDALRVLHERVPETRGVAIRRIVAGVKIDDLDPGHVLPNLGNYAVRGCWFPLGYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKY6</accession>
    <name>A0A0S2DKY6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alanine dehydrogenase/pyridine nucleotide transhydrogenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">NAD(P) transhydrogenase subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_19015</name>
        <name evidence="5" type="ORF">GLE_3869</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AlaDH/PNT family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW27416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948608.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3869"/>
    <dbReference type="EnsemblBacteria" id="ALN59212">
        <property type="protein sequence ID" value="ALN59212"/>
        <property type="gene ID" value="GLE_3869"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3869"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3808"/>
    <dbReference type="OMA" id="YFPMLMT"/>
    <dbReference type="OrthoDB" id="464096at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008143">
        <property type="entry name" value="Ala_DH/PNT_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01262">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01002">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00837">
        <property type="entry name" value="ALADH_PNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlaDh_PNT_N" evidence="4">
        <location>
            <begin position="7"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="AlaDh_PNT_C" evidence="3">
        <location>
            <begin position="151"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW27416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="372" mass="38674" checksum="57CD43B3DAA72ACB" modified="2016-02-17" version="1">MSGITIGVASETAAGEQRVALTPETCKKLIARGARVRIQRGAGRGASFTDEAYVQAGAELADDAAGATAQADVVLCVQAPDGERLNLLREGAALVGLLQPQADATRGEAIVARQLLAFPLERLPRTTRAQAMDVLSSQAGMAGYKAVLIAAQLAPRFFPMLTTAAGTIRPSRVLIVGAGVAGLQAVATAKRLGAQVEGFDVRPETREQIESLGGKFLDLGVSAAGEGGYARQLTDEERAEQQRRLGEHLKNVDVIVCTAAVPGRPAPKIVTAAMIAGMKPGSVLVDLAAETGGNCELTRPGETVDANGVTIAGPLNLASAGAVHASEMFARNVLNFVSLFVDGGELKYDWDDELLAKTVWPERKAQAQSAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL30</accession>
    <name>A0A0S2DL30_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-(apurinic or apyrimidinic site) lyase</fullName>
            <ecNumber evidence="2">4.2.99.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">mutM</name>
        <name evidence="12" type="ORF">FE772_18195</name>
        <name evidence="11" type="ORF">GLE_3693</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FPG family.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948477.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59037">
        <property type="protein sequence ID" value="ALN59037"/>
        <property type="gene ID" value="GLE_3693"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3693"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3637"/>
    <dbReference type="OMA" id="SWGKHFL"/>
    <dbReference type="OrthoDB" id="1162346at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019104">
        <property type="term" value="F:DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015886">
        <property type="entry name" value="DNA_glyclase/AP_lyase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012319">
        <property type="entry name" value="FPG_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035937">
        <property type="entry name" value="MutM-like_N-ter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01149">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06831">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00898">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01232">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81624">
        <property type="entry name" value="SSF81624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51068">
        <property type="entry name" value="FPG_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="12" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FPG_CAT" evidence="10">
        <location>
            <begin position="2"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN59037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW27279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="252" mass="28977" checksum="7AA7F3442EB7C8BA" modified="2016-02-17" version="1">MPEGPTIVILKEEAAAFDGRVVERVAGNSTQDIQRMRGRRIRAIRSWGKHFLLEFSGFSLRVHLMLYGSYRINERREAAPRLNLQFAGGDELNFYACSVKFIETPLDEVYDWSADVMNPHWDPKSARAKLKQMPQALAADALLDQNVFSGVGNIIKNEVLHRIRLHPESPIGALPPRKLGELIAQARDYSFDFYRWKKAYELKRHLQVHTKTHCPRDGARLSFRKHLGRYKRRAFFCPLCQRLYAPAADTAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLC3</accession>
    <name>A0A0S2DLC3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4041</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59383">
        <property type="protein sequence ID" value="ALN59383"/>
        <property type="gene ID" value="GLE_4041"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4041"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3983"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="84" mass="10110" checksum="CA4D7090D6DBB4E3" modified="2016-02-17" version="1">MTVFEALDHVTYTPDTFTGYWLIENLPKGMSMLDWYGPRYRHCIKRDAKLIEAKCIMQEATFDHWRYAPRKGLKLLDARRGEWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLD4</accession>
    <name>A0A0S2DLD4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Tol-Pal system protein TolR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 7" type="primary">tolR</name>
        <name evidence="8" type="ORF">FE772_19910</name>
        <name evidence="7" type="ORF">GLE_4055</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell inner membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948747.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4055"/>
    <dbReference type="EnsemblBacteria" id="ALN59397">
        <property type="protein sequence ID" value="ALN59397"/>
        <property type="gene ID" value="GLE_4055"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4055"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3998"/>
    <dbReference type="OMA" id="YITEKAM"/>
    <dbReference type="OrthoDB" id="1940365at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02203">
        <property type="entry name" value="TolR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014168">
        <property type="entry name" value="Tol-Pal_TolR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30558">
        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02801">
        <property type="entry name" value="tolR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW27569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="147" mass="15908" checksum="321220B3430EE8F4" modified="2016-02-17" version="1">MSGTIRRPNKRKLKADINVVPYIDVMLVLLIIFMVTAPLLTLGVDVDLPKSNAKSSNTKTDPVVVQVDEAGNFFLTVKAGNKEAVTAQDLAAKVGAIVKQNDKEKLQVYIAGDGRANYQPVMDAMNILQSAGVEKVSLISQPEKGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLJ1</accession>
    <name>A0A0S2DLJ1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59452">
        <property type="protein sequence ID" value="ALN59452"/>
        <property type="gene ID" value="GLE_4110"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4110"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4052"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="47" mass="5153" checksum="1DBC6DE43C001338" modified="2016-02-17" version="1">MSQGATSTRSGEVGMWRHAPRTPTQSAPVLSEDAQQHVCRDLPKCPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLK8</accession>
    <name>A0A0S2DLK8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Cell division protein FtsZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 8" type="primary">ftsZ</name>
        <name evidence="9" type="ORF">FE772_20225</name>
        <name evidence="8" type="ORF">GLE_4126</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="4">Assembles at midcell at the inner surface of the cytoplasmic membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the FtsZ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948806.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4126"/>
    <dbReference type="EnsemblBacteria" id="ALN59468">
        <property type="protein sequence ID" value="ALN59468"/>
        <property type="gene ID" value="GLE_4126"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4126"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4068"/>
    <dbReference type="OMA" id="GNPSIGQ"/>
    <dbReference type="OrthoDB" id="1009041at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051258">
        <property type="term" value="P:protein polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02201">
        <property type="entry name" value="FtsZ_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00909">
        <property type="entry name" value="FtsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000158">
        <property type="entry name" value="Cell_div_FtsZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020805">
        <property type="entry name" value="Cell_div_FtsZ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024757">
        <property type="entry name" value="FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="PTHR30314"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12327">
        <property type="entry name" value="FtsZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00423">
        <property type="entry name" value="CELLDVISFTSZ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="SSF52490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="SSF55307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00065">
        <property type="entry name" value="ftsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01135">
        <property type="entry name" value="FTSZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 5 8" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0717">Septation</keyword>
    <feature type="domain" description="Tubulin" evidence="6">
        <location>
            <begin position="15"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin_C" evidence="7">
        <location>
            <begin position="209"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="23"/>
            <end position="27"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="110"/>
            <end position="112"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW27620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="410" mass="42650" checksum="916CAAAA8F6387B6" modified="2016-02-17" version="1">MAHFELVEKMAPNAVIKVVGVGGGGGNAVAHMVSGNVDGVEFITANTDAQAIKNCGAKLQLQLGSNVTKGLGAGANPEVGRQAALEDRERIMDALTGADMVFITAGMGGGTGTGAAPVVAQLAKEMGILTVAVVTKPFPFEGRRRMQVALKGIEELSHHCDSLITIPNEKLITVLGRNATMIQAFRAANDVLLGAVQGIADLIVRPGLINVDFADVRTVMSEMGLAMMGTGAARGDDRAQAAAESAIQNPLLDDVNLAGANGILVNITAGPDFTMAEFDEVGRTIENFASEDATVVIGTVLDPDMQDEVKVTVVATGLNRVAAKQSVRGHGSSHGFEREAQRAPIQLVRNATTGQPEFSAMDDVGHAPMPSFGGNLRGSARQEPTGPAVADFGSDNSYLDIPAFLRRQAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLU6</accession>
    <name>A0A0S2DLU6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_20075</name>
        <name evidence="2" type="ORF">GLE_4091</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4091"/>
    <dbReference type="EnsemblBacteria" id="ALN59433">
        <property type="protein sequence ID" value="ALN59433"/>
        <property type="gene ID" value="GLE_4091"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4091"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4033"/>
    <dbReference type="OMA" id="NGAFYWW"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="215" mass="23273" checksum="327EEB7197789960" modified="2016-02-17" version="1">MISTTQSQPNRPAPRRHELRPLLAGPAQLAILAVLLTLMAATRFHAVGSALHLPDASMAVFFLGGLYLQRHRLFAGLLVAAVAIDYIAVTGRGLSFFDHYCVTPSYAFLLLAYAVLWYLGRAWAPSMAARPRALAGALAVALVAASASFLISNGAFYWFGGRYADPNFAQYIERVWRWGPLFVGTTMAYVGTALLAHALVARFARPRGAASGPRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM03</accession>
    <name>A0A0S2DM03_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DnaJ domain</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">J domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BV903_04615</name>
        <name evidence="6" type="ORF">FE772_21000</name>
        <name evidence="4" type="ORF">GLE_4289</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">C3</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000008">
        <property type="protein sequence ID" value="OPD65206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948937.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000008.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4289"/>
    <dbReference type="EnsemblBacteria" id="ALN59630">
        <property type="protein sequence ID" value="ALN59630"/>
        <property type="gene ID" value="GLE_4289"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65206">
        <property type="protein sequence ID" value="OPD65206"/>
        <property type="gene ID" value="BV903_04615"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4289"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4228"/>
    <dbReference type="OMA" id="FRPNPLF"/>
    <dbReference type="OrthoDB" id="2072656at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="47"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD65206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW27752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="112" mass="12990" checksum="D42354F4D8D2BF89" modified="2016-02-17" version="1">MKQNWYGKLLGFCVGLALSRGNPWVALVGLLIGHAVDTDWFRLRRDDPYATLGLDREASDAEIDKAYRRLISQHHPDRYANDPAEARERAEARAREINRAYDRIRALRKRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM04</accession>
    <name>A0A0S2DM04_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dgpfaetke domain containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">YciI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_21385</name>
        <name evidence="3" type="ORF">GLE_4377</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YciI family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949003.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4377"/>
    <dbReference type="EnsemblBacteria" id="ALN59718">
        <property type="protein sequence ID" value="ALN59718"/>
        <property type="gene ID" value="GLE_4377"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4377"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4316"/>
    <dbReference type="OMA" id="ELFGGFY"/>
    <dbReference type="OrthoDB" id="2051456at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII" evidence="2">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="129" mass="14127" checksum="3B63D5BEF9FBAC64" modified="2016-02-17" version="1">MRFMMLMIPQGYESAEPGTLPSAERIATMMEYNRALQEAGVLRALDGLHPPSMGARVGFRGGASRVVDGPFPEAKEVLGGYWVIEVGSREEAIAWARRCPGADNETIEVRQIMGMDDFPEDVQQAVGQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM92</accession>
    <name>A0A0S2DM92_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Lytic transglycosylase domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Transglycosylase SLT domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_21330</name>
        <name evidence="4" type="ORF">GLE_4365</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transglycosylase Slt family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948995.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4365"/>
    <dbReference type="EnsemblBacteria" id="ALN59706">
        <property type="protein sequence ID" value="ALN59706"/>
        <property type="gene ID" value="GLE_4365"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4365"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4304"/>
    <dbReference type="OMA" id="WLRAIAH"/>
    <dbReference type="OrthoDB" id="1444566at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008933">
        <property type="term" value="F:lytic transglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000270">
        <property type="term" value="P:peptidoglycan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000189">
        <property type="entry name" value="Transglyc_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008258">
        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00922">
        <property type="entry name" value="TRANSGLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242343" evidence="2">
        <location>
            <begin position="33"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="SLT" evidence="3">
        <location>
            <begin position="136"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW27806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="269" mass="29011" checksum="0977239263C3C121" modified="2016-02-17" version="1">MTAPARPRTLVLRFAVAVAFALLALANTAVQARTVYRCVRDGTVSLATAPEPGSRCEAKQIDDNAVKLPNLWGELGVINGNLYERQQDGKTVYSTRNLPGSVRVMGFSVETPPGEPAHPGLGKVGKPQLDKFAAQFRSAAKANGLDDAWLRAIAHAESGFDARAVSSKGAQGVMQLMPETAKEYGVVDPFSSDESIKAGARHLKSLLRRYNNDLTLATAAYNAGIGTVTRYRGVPPYRETQEYIAKVEALVQRYQLALGTRKPALRAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMK1</accession>
    <name>A0A0S2DMK1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Maleylacetoacetate isomerase</fullName>
            <ecNumber evidence="4">5.2.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">maiA</name>
        <name evidence="5" type="ORF">FE772_20840</name>
        <name evidence="4" type="ORF">GLE_4256</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily. Zeta family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.2" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948908.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4256"/>
    <dbReference type="EnsemblBacteria" id="ALN59597">
        <property type="protein sequence ID" value="ALN59597"/>
        <property type="gene ID" value="GLE_4256"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4256"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4196"/>
    <dbReference type="OMA" id="VYNAHRF"/>
    <dbReference type="OrthoDB" id="1527209at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016034">
        <property type="term" value="F:maleylacetoacetate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009072">
        <property type="term" value="P:aromatic amino acid family metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03191">
        <property type="entry name" value="GST_C_Zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03042">
        <property type="entry name" value="GST_N_Zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005955">
        <property type="entry name" value="GST_Zeta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034330">
        <property type="entry name" value="GST_Zeta_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034333">
        <property type="entry name" value="GST_Zeta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01262">
        <property type="entry name" value="maiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="3"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="91"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW27722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="220" mass="25043" checksum="41E1AB00555FC82C" modified="2016-02-17" version="1">MNDQLRLHSYWRSSASYRVRIGLNLKGLEYETVPVHLVRNGGEQHDPAYRALNPQGLVPVLQHGSRTLTQSIAILEYLDEVWPRPNLLPTTARDRHRVRAIAQTIACEIHPLNNLRVLQYLDGTWNVPQPEREGWIKHWIVEGFTAVEAMLREHPATGVFCEGDTPGLADCCLIPQLYNARRFGAPLEAFPTLLRIERACLELAEFDRARPENQPDCPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMQ0</accession>
    <name>A0A0S2DMQ0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycosyl hydrolase family 25 lysozyme</fullName>
            <ecNumber evidence="5">3.2.1.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BV903_03510</name>
        <name evidence="5" type="ORF">GLE_4515</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">B25</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 25 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.17" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000006">
        <property type="protein sequence ID" value="OPD65366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4515"/>
    <dbReference type="EnsemblBacteria" id="ALN59856">
        <property type="protein sequence ID" value="ALN59856"/>
        <property type="gene ID" value="GLE_4515"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65366">
        <property type="protein sequence ID" value="OPD65366"/>
        <property type="gene ID" value="BV903_03510"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4515"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4451"/>
    <dbReference type="OMA" id="GSYNVGM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003796">
        <property type="term" value="F:lysozyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016998">
        <property type="term" value="P:cell wall macromolecule catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002053">
        <property type="entry name" value="Glyco_hydro_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018077">
        <property type="entry name" value="Glyco_hydro_fam25_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01183">
        <property type="entry name" value="Glyco_hydro_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00641">
        <property type="entry name" value="Glyco_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51904">
        <property type="entry name" value="GLYCOSYL_HYDROL_F25_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="13"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD65366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="261" mass="28641" checksum="87ED003A063F1A8D" modified="2016-02-17" version="1">MPDQFDRTRWRRIAMRTVAVAATALAIGIAARWWFLHWQPDRARYPLRGIDVSHHQGAIDWRAVARDDVAFAYLKASEGGDHRDRRYAANARDARAAGVAVGAYHFFTFCRDGGAQAANFLAAAPAAADALPPAVDLEFGGNCGRRPDGAAMRAELDAFLAPVEAAYGKPALLYVTPEFFDAYRAALPSRPLWRRAILRAPDSRAAWTLWQYHNRARVAGIDGPVDLNVFDGDAAAFARWRDMNAQPRDPPAGAARAASVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMS2</accession>
    <name>A0A0S2DMS2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_21590</name>
        <name evidence="2" type="ORF">GLE_4420</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949041.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59761">
        <property type="protein sequence ID" value="ALN59761"/>
        <property type="gene ID" value="GLE_4420"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4420"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4358"/>
    <dbReference type="OMA" id="THEACTT"/>
    <dbReference type="OrthoDB" id="5971at68"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242463" evidence="1">
        <location>
            <begin position="30"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="172" mass="17666" checksum="750BD524BA38ED3C" modified="2016-02-17" version="1">MNMRKSGRVAAIAALWGLALAGAALPAAAADWVHSGRYQYFSEGPLGGNGSNGCQGGATPLASGDCIADPGTGWAANFNAAMAAADAVEATGVCVLGYQYPSSCRFAGYALNGQGVSASENFYAPNDLPRPCVAGTYAVGYVIFRRVVDAQDGSADDRGIESDYSADEYQCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMZ3</accession>
    <name>A0A0S2DMZ3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">tRNA nucleotidyltransferase</fullName>
            <ecNumber evidence="5">2.7.7.72</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_4444</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.72" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4444"/>
    <dbReference type="EnsemblBacteria" id="ALN59785">
        <property type="protein sequence ID" value="ALN59785"/>
        <property type="gene ID" value="GLE_4444"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4444"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4381"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052929">
        <property type="term" value="F:ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052928">
        <property type="term" value="F:CTP:3'-cytidine-tRNA cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052927">
        <property type="term" value="F:CTP:tRNA cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016437">
        <property type="term" value="F:tRNA cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PolyA_pol" evidence="4">
        <location>
            <begin position="42"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="694" mass="76675" checksum="6207CA73D7700F71" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN62</accession>
    <name>A0A0S2DN62_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4814</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60155">
        <property type="protein sequence ID" value="ALN60155"/>
        <property type="gene ID" value="GLE_4814"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4814"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="46" mass="5226" checksum="5721FD38324EC7C0" modified="2016-02-17" version="1">MRAIACSAAPRSDRIASSMARASRRGAIRRMRAVTNPQRQRRSRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN76</accession>
    <name>A0A0S2DN76_LYSEN</name>
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        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_4600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C40 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_4600"/>
    <dbReference type="EnsemblBacteria" id="ALN59941">
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        <property type="gene ID" value="GLE_4600"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4600"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4535"/>
    <dbReference type="OMA" id="YLKGHIM"/>
    <dbReference type="OrthoDB" id="682655at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000064">
        <property type="entry name" value="NLP_P60_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027017">
        <property type="entry name" value="P60_peptidase_YkfC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
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        <property type="entry name" value="SH3b1_dom"/>
    </dbReference>
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        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SH3_6"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595495" evidence="2">
        <location>
            <begin position="33"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="SH3_6" evidence="4">
        <location>
            <begin position="177"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="NlpC/P60" evidence="3">
        <location>
            <begin position="343"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="483" mass="53849" checksum="9BC56B9006E64503" modified="2016-02-17" version="1">MGTAPSRRRPTRTRALARCIAASALLSGTLFAQSPSTAPAAARDRGIPATGVIGIEEGQLNADYWIRQQRKPDAVILDGRAIARQNARLAELDASVHDIERLPATLPHERVREWIAAISQARDEPLFDERGEDVPAATLRGFDAELALDAIPAQQAVRYGLVVRRADLRTFPTRMRVFNSRGDTDIDRFQESALFPGTPVAVAHESRDRKYWFVVSPLYAAWVEKDRVALGDKPAVFAYTRKTPYLVVTGATARTVHTPEQPGVSDVQLEMGVRVPLLADWPADRPVNGQHHYASHVIELPYRDADGTLKFSPALLPRTADTAADYLPLTQANLVRQGFKFFGERYGWGHSYNTRDCSGFVSEIYRSFGVQLPRNTRDQAVSPAYNRIDLDETLGHEERLKIVKTLEVGDLIYIPGHVMMVVGHEDGWPYVIHDTTGITFRDRTGDLARVHLNGVSVTPLVPLLFNKEQPTVDRITSIQRIRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN98</accession>
    <name>A0A0S2DN98_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">VWA domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">von Willebrand factor, type A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_22945</name>
        <name evidence="2" type="ORF">GLE_4717</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60058">
        <property type="protein sequence ID" value="ALN60058"/>
        <property type="gene ID" value="GLE_4717"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4717"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4651"/>
    <dbReference type="OMA" id="MINYFDY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021908">
        <property type="entry name" value="DUF3520"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022156">
        <property type="entry name" value="Uncharacterised_YfbK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12034">
        <property type="entry name" value="DUF3520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12450">
        <property type="entry name" value="vWF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="1">
        <location>
            <begin position="176"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="550" mass="58641" checksum="F815FC63F4B9FC0A" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNA1</accession>
    <name>A0A0S2DNA1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptidase, families S8 and S53</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_21650</name>
        <name evidence="7" type="ORF">GLE_4434</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949050.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59775">
        <property type="protein sequence ID" value="ALN59775"/>
        <property type="gene ID" value="GLE_4434"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4434"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4371"/>
    <dbReference type="OMA" id="LCHPELV"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04059">
        <property type="entry name" value="Peptidases_S8_Protein_convertases_Kexins_Furin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034182">
        <property type="entry name" value="Kexin/furin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002884">
        <property type="entry name" value="P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
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        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01483">
        <property type="entry name" value="P_proprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51829">
        <property type="entry name" value="P_HOMO_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242348" evidence="5">
        <location>
            <begin position="27"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="P/Homo B" evidence="6">
        <location>
            <begin position="456"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW27865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="587" mass="61300" checksum="3A8F320073478C3A" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="Swiss-Prot" created="2022-05-25" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNG5</accession>
    <name>GSDM_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Gasdermin bGSDM</fullName>
            <shortName evidence="6">bGSDM</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Bacterial gasdermin</fullName>
        </alternativeName>
        <component>
            <recommendedName>
                <fullName evidence="7">Gasdermin bGSDM, N-terminus</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_23055</name>
        <name evidence="6" type="ORF">Ga0399710_4913</name>
        <name evidence="4" type="ORF">GLE_4743</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="2015" name="BMC Genomics" volume="16" first="991" last="991">
            <title>Comparative genomics and metabolic profiling of the genus Lysobacter.</title>
            <authorList>
                <person name="de Bruijn I."/>
                <person name="Cheng X."/>
                <person name="de Jager V."/>
                <person name="Exposito R.G."/>
                <person name="Watrous J."/>
                <person name="Patel N."/>
                <person name="Postma J."/>
                <person name="Dorrestein P.C."/>
                <person name="Kobayashi D."/>
                <person name="Raaijmakers J.M."/>
            </authorList>
            <dbReference type="PubMed" id="26597042"/>
            <dbReference type="DOI" id="10.1186/s12864-015-2191-z"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>C3</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="2019" name="Appl. Environ. Microbiol." volume="85" first="0" last="0">
            <title>Interspecies and Intraspecies Signals Synergistically Regulate Lysobacter enzymogenes Twitching Motility.</title>
            <authorList>
                <person name="Feng T."/>
                <person name="Han Y."/>
                <person name="Li B."/>
                <person name="Li Z."/>
                <person name="Yu Y."/>
                <person name="Sun Q."/>
                <person name="Li X."/>
                <person name="Du L."/>
                <person name="Zhang X.H."/>
                <person name="Wang Y."/>
            </authorList>
            <dbReference type="PubMed" id="31540995"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>YC36</strain>
        </source>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2022" name="Science" volume="375" first="221" last="225">
            <title>Bacterial gasdermins reveal an ancient mechanism of cell death.</title>
            <authorList>
                <person name="Johnson A.G."/>
                <person name="Wein T."/>
                <person name="Mayer M.L."/>
                <person name="Duncan-Lowey B."/>
                <person name="Yirmiya E."/>
                <person name="Oppenheimer-Shaanan Y."/>
                <person name="Amitai G."/>
                <person name="Sorek R."/>
                <person name="Kranzusch P.J."/>
            </authorList>
            <dbReference type="PubMed" id="35025633"/>
            <dbReference type="DOI" id="10.1126/science.abj8432"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>DISRUPTION PHENOTYPE</scope>
        <scope>MUTAGENESIS OF CYS-7</scope>
        <source>
            <strain>YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <molecule>Gasdermin bGSDM</molecule>
        <text evidence="2 3">Involved in defense against bacteriophages. When this probable 4 gene operon (bGSDM-FE772_23060-FE772_23065-FE772_23070) is inserted into E.coli it provides nearly 100-fold protection against phages T5 and T6 and about 8-fold against phage T4. The operon without bGSDM no longer protects against phage (PubMed:35025633). Cleavage of this precursor by its dedicated protease(s) releases the active moiety (gasdermin bGSDM, N-terminus) which inserts into membranes, forming pores and triggering cell death.</text>
    </comment>
    <comment type="function">
        <molecule>Gasdermin bGSDM, N-terminus</molecule>
        <text evidence="2">Pore-forming protein that causes membrane permeabilization via a pyroptosis-like activity. Makes ring-like pores when released.</text>
    </comment>
    <comment type="activity regulation">
        <molecule>Gasdermin bGSDM</molecule>
        <text evidence="2">The full-length protein before cleavage is inactive: intramolecular interactions between the N-terminal domain and the C-terminal region as well as the lipid modification, mediate autoinhibition. The pyroptosis-like-inducing activity is carried by the released N-terminal domain (Gasdermin bGSDM, N-terminus).</text>
    </comment>
    <comment type="subunit">
        <molecule>Gasdermin bGSDM</molecule>
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="subunit">
        <molecule>Gasdermin bGSDM, N-terminus</molecule>
        <text evidence="2">Forms large, probably homooligomeric ring-shaped pores when inserted in membranes.</text>
    </comment>
    <comment type="subcellular location">
        <molecule>Gasdermin bGSDM</molecule>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="subcellular location">
        <molecule>Gasdermin bGSDM, N-terminus</molecule>
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="2">The N-terminus has marked structural similarity to the mammalian gasdermin N-terminal domain. The C-terminal region wraps around the twisted beta sheet core, probably stabilizing the inactive state.</text>
    </comment>
    <comment type="PTM">
        <text evidence="1">Palmitoylation helps stabilize the inactive state; may self palmitoylate.</text>
    </comment>
    <comment type="disruption phenotype">
        <text evidence="3">When deleted from its operon, no longer protects E.coli against bacteriophages T4, T5 or T6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial gasdermin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949280.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60084">
        <property type="protein sequence ID" value="ALN60084"/>
        <property type="gene ID" value="GLE_4743"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4743"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4677"/>
    <dbReference type="OMA" id="TQRDEVE"/>
    <dbReference type="OrthoDB" id="1715617at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword id="KW-0051">Antiviral defense</keyword>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0449">Lipoprotein</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0564">Palmitate</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="chain" id="PRO_0000455570" description="Gasdermin bGSDM">
        <location>
            <begin position="1"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_0000455571" description="Gasdermin bGSDM, N-terminus">
        <location>
            <begin position="1"/>
            <end status="unknown"/>
        </location>
    </feature>
    <feature type="region of interest" description="C-terminal region" evidence="7">
        <location>
            <begin status="unknown"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="lipid moiety-binding region" description="S-palmitoyl cysteine" evidence="1">
        <location>
            <position position="7"/>
        </location>
    </feature>
    <feature type="mutagenesis site" description="4-gene operon still protects against phage." evidence="3">
        <original>C</original>
        <variation>A</variation>
        <location>
            <position position="7"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1">
        <source>
            <dbReference type="UniProtKB" id="P0DV46"/>
        </source>
    </evidence>
    <evidence type="ECO:0000250" key="2">
        <source>
            <dbReference type="UniProtKB" id="P0DV48"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="3">
        <source>
            <dbReference type="PubMed" id="35025633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="4">
        <source>
            <dbReference type="PubMed" id="26597042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="5">
        <source>
            <dbReference type="PubMed" id="31540995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000303" key="6">
        <source>
            <dbReference type="PubMed" id="35025633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="7"/>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN60084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="271" mass="28450" checksum="098999A7443A0A8D" modified="2016-02-17" version="1">MSILPGCKDPSLSALKSKGYNVVQLPRADLRPTQLLVEKSKRLQRLGELLSVFDAAADGPPAPPVSADRPGPNIAGTQSADLDVDLGLSVLRGIISALGGSTLGVDAAFARAATVQFEFSSTLENNSELALIDRFLAASRVNPHARAVAEMLEQDQVYVVTSTLKAQRINVAAKDSNKQSLGLNLPVIQDAIGANVKIAAAAASGSTVSFEGAVPLVFGFQAVRLIFEQGRYRTMRLVDAGGVVAEAVRPDGAADGEPPCYLDVEAMLLDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNH0</accession>
    <name>A0A0S2DNH0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_23515</name>
        <name evidence="1" type="ORF">GLE_4841</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949353.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60182">
        <property type="protein sequence ID" value="ALN60182"/>
        <property type="gene ID" value="GLE_4841"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4841"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4771"/>
    <dbReference type="OrthoDB" id="1962600at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="103" mass="11790" checksum="97BE6AFA5CC7991C" modified="2016-02-17" version="1">MKNVQVVDGAINCVYDVFALDDADFALLFPPGQDVAFIDEILARHPPAALEPVFERLWRNRVPKREVVGLHGLLFYQLDEKKPFYPQRVDELAVNPNGSKLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNI3</accession>
    <name>A0A0S2DNI3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_23590</name>
        <name evidence="2" type="ORF">GLE_4857</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949365.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60198">
        <property type="protein sequence ID" value="ALN60198"/>
        <property type="gene ID" value="GLE_4857"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4857"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4787"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="193" mass="21596" checksum="2C400147F7C7FCD2" modified="2016-02-17" version="1">MSNPAPAEVRRINRLYWIELILAWAGLCASIVWSSEYAETFQYSRDAAWMRWASHALLVALSLGCFAALQRWQPRLAPDRPLTGMNLILTMMVAIGLYALLDIVPIALHRGADPQPLTAVASADPRYSSWSRNCKRRVWIQGDTPLRGLRLCVRDRAMYEQLTASRRIEIAATASPYGIAIQSFRAAPAAQNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNV7</accession>
    <name>A0A0S2DNV7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10 11">Glutathione-regulated potassium-efflux system protein KefB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">kefB</name>
        <name evidence="11" type="ORF">FE772_23915</name>
        <name evidence="10" type="ORF">GLE_4929</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.</text>
    </comment>
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        <property type="gene ID" value="GLE_4929"/>
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    <dbReference type="OrthoDB" id="941006at2"/>
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    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:cation transmembrane transporter activity"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="P:potassium ion transport"/>
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    <feature type="transmembrane region" description="Helical" evidence="8">
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    <feature type="transmembrane region" description="Helical" evidence="8">
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    <feature type="transmembrane region" description="Helical" evidence="8">
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            <end position="515"/>
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        <location>
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        <source>
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        <source>
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        <source>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
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        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN60270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW28238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="613" mass="65648" checksum="928FB75081888266" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNX1</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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            <end position="84"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="84" mass="9222" checksum="9F842259E598C9E1" modified="2016-02-17" version="1">MRSGLSLKPIANLRHPAAGAARAATAKPRLRRELEVSRSRLAPLLQSESKPRWVPARAIPKTKKPSREARAFRGEPDRLSASSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="13" xmlns="http://uniprot.org/uniprot">
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        </submittedName>
    </protein>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="84" mass="9081" checksum="4DD83BE68D593AB6" modified="2016-02-17" version="1">MQCRDRCGACCIAPSITSPIPGMPHGKPAGIPCVQLDDELRCRLFGRPERPRFCGSLQPQAEMCGQSREQALAGLLELDRATAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPA9</accession>
    <name>A0A0S2DPA9_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">DUF4350 domain-containing protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">FE772_24240</name>
        <name evidence="2" type="ORF">GLE_5000</name>
    </gene>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN60341">
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        <property type="gene ID" value="GLE_5000"/>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <feature type="domain" description="DUF4350" evidence="1">
        <location>
            <begin position="48"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="408" mass="45693" checksum="77590AFF6C66A3AE" modified="2016-02-17" version="1">MGRMSRQGLIALALLALVALLGFGGYSLWRKDYVRSEEMVDLPRTGEAASNPLYVLKLALAKDGVKVDARQRLLLSQHPLQPRDTVLIYRDPRTLAAPDAKALLEWVARGGHLIVRTPPWRERLGEAKVPVLEEVGVTLLDAADNEDNGQRSGCANLYERGRESQLVFCGARRFYFYNADAAPEAAWGDEDSAYVYARLPYGEGRVDVLADMDFLSNRGGSALAAFAGVRHGDDEVAQPSNAAFARQVLAPNYRAGTIHLIYAADVPSLWQTLIRNSWMAWLPLLLWLAAWLWQRMQRFGPLRPAPAMERRSLLEHIVASGEHIYRYGYGPSLYASVRAAFLLRLRRRDPYAASIEGEAQLELLAQRYKNEPGLGPAQIRDALAHPLARDHAAFRTRIATLIRMRNRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPD8</accession>
    <name>A0A0S2DPD8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4683</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60024">
        <property type="protein sequence ID" value="ALN60024"/>
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</entry>
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            <authorList>
                <person name="Feng T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
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    <accession>A0A0S2DPV5</accession>
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                <person name="Feng T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </evidence>
    <sequence length="436" mass="46479" checksum="1D8814B886AE1FA2" modified="2016-02-17" version="1">MSRPRIDASHDPALRSWVEGAQDHAQFPIQNLPYGVFAPPGEAARAGAAIGDCILDLRAAAAAGALPADAVPALRGDSLNELFALAPAARAALRLALSRLLSDEACAAAARPWLHRADDCALQLPMRIGDYTDFYAGIHHAENVGRLFRPDRPLLANYKHLPIGYHGRASSVRASGAPVRRPHGQWLAAADAEPEFGPSRRLDFELELGVWIGRGNRLGEPVPIAEAHAHIAGLCLLNDWSARDLQAWEYQPLGPFLGKSFLTTVSPWVVTAEALAPFAVAAPARPAGDPAPLPYLDDPGDRSHGGYAIELEVALRTARMRRDDAPAQTLTRTAAARLYWTAAQMIAHHTSNGCNLQPGDLLGSGTVSGPGEDECGSLLERSRGGRQPLTLANGELRSFLEDGDEVSLNATARAPGYVPIGFGECRGRVVTDSDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ26</accession>
    <name>A0A0S2DQ26_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Lipoprotein VacJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">vacJ</name>
        <name evidence="4" type="ORF">GLE_5238</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MlaA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5238"/>
    <dbReference type="EnsemblBacteria" id="ALN60579">
        <property type="protein sequence ID" value="ALN60579"/>
        <property type="gene ID" value="GLE_5238"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5238"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5156"/>
    <dbReference type="OMA" id="HAFNNVV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007428">
        <property type="entry name" value="MlaA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30035">
        <property type="entry name" value="PTHR30035"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04333">
        <property type="entry name" value="MlaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01805">
        <property type="entry name" value="VACJLIPOPROT"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="361"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="391" mass="41278" checksum="3FE888B3EDDFCF5A" modified="2016-02-17" version="1">MALAAHTVPAAAQDAAPVLPGDPSALTIDTAALAAAAQADAATQATDAGAPVLTDSARALDAAVAATDAAQAEALAGASAIADAQPAPAPDASLDYALAQVDPTAAATPPAEPAAAADDPRTQAERDFDALYGNPQGEYNPVADPTLPAPANVPGGYDPWEKYNRKMHRFNNAVDRGVAKPLARAYTKVVPRPIRLGVSNFFNNLGQPVSMVNALLQGKPKQAAQSLGRFALNTTLGIGGIFDPATAAKLPNRSEDFGQTLGVWGWKRSRYFELPFFGPRTVRDAFGAVGDAPLSPLRRIERDRIRIGLQGLQLVDIRAQLLPLDNLREGAEDEYALVRDSWMQRRDYQIFGDRLEKNGDTALPDYLQDDSNPSVPANAMPVMPTDGAGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ42</accession>
    <name>A0A0S2DQ42_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA binding domain, excisionase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_5349</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949741.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60690">
        <property type="protein sequence ID" value="ALN60690"/>
        <property type="gene ID" value="GLE_5349"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5349"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5265"/>
    <dbReference type="OMA" id="AEVYFVN"/>
    <dbReference type="OrthoDB" id="886332at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03408">
        <property type="entry name" value="SPFH_like_u1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010093">
        <property type="entry name" value="SinI_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033880">
        <property type="entry name" value="SPFH_YdjI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13421">
        <property type="entry name" value="Band_7_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01764">
        <property type="entry name" value="excise"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band_7_1" evidence="2">
        <location>
            <begin position="27"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_17" evidence="1">
        <location>
            <begin position="304"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="352" mass="37870" checksum="BB5BA45D7DD35363" modified="2016-02-17" version="1">MSILGFIKGELLEIIEWTDDSRDTLSYRYPDDDKEIKNGAQLIVRESQQVQFVAAGQYADLFGPGKHTLKTENIPVLSTILGWKYGFDSPFKCDVYFLNTRLFTGNKWGTANPVMMRDADFGVVRLRAFGTYDFRIVDPPKFLREVAGTDQNFRLDEFADTMRSRIVSVFTEALATAKVPALDVASRYSELGDALLPVINPAMTSKYGIEITSFVLENVSVPPEVEKAIDARSSMSAVGNLNDYVKFQMGSAMGQGGDASAAVPAQMAVGFGIAQEMMRGMQGAAPAQAAAPGDAAPAAAGLEVLTPEQAAAALGVSVEDVMAAIAAGDLKARKIGNATRIARSALEEFLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ74</accession>
    <name>A0A0S2DQ74_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5325</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60666">
        <property type="protein sequence ID" value="ALN60666"/>
        <property type="gene ID" value="GLE_5325"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5325"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5242"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="52" mass="6113" checksum="F527A2743AA37B90" modified="2016-02-17" version="1">MDVWRRGFDLIDLSMARIPARNPRSCPHRSKRADRPEKCLELSIFMNGLENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQE1</accession>
    <name>A0A0S2DQE1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_00120</name>
        <name evidence="3" type="ORF">GLE_5366</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949752.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5366"/>
    <dbReference type="EnsemblBacteria" id="ALN60707">
        <property type="protein sequence ID" value="ALN60707"/>
        <property type="gene ID" value="GLE_5366"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5366"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5281"/>
    <dbReference type="OMA" id="DEHSDIG"/>
    <dbReference type="OrthoDB" id="1730786at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="120" mass="12607" checksum="C8453725047E5881" modified="2016-02-17" version="1">MSKFDSLPDRALELVHAISANLKEAAPKAGQWLDTGAKFGVVKAGARTAGGFIRRNPVVAVAAVAGAGLLWYAAARRKARQQAEGEPIEGSARRIDARRAAPGAGRRRSTRNTAEDTAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQI0</accession>
    <name>A0A0S2DQI0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_00185</name>
        <name evidence="3" type="ORF">GLE_5380</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949763.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60721">
        <property type="protein sequence ID" value="ALN60721"/>
        <property type="gene ID" value="GLE_5380"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5380"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5295"/>
    <dbReference type="OrthoDB" id="2203866at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="85"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="268" mass="29138" checksum="4C1FA1FB3EEE27D4" modified="2016-02-17" version="1">MQAETPRGRSDTGSSQAIELSGTTLDAIITDIDRLKRQSQSAIPFGLAGLALVVGGLVYSGWQLNNVRRDIADKRQEMADVDLSLNAKAAQLAESEKRLSEAREQRESLQIEINNLAERIDAVASAPNAAQKNAELNAAMVQAKDLNAAIASAAANDSAPPRYGAYKVDIFYCADRTARNKPLAERARTLGQDGAAQGEWRVRELSEKSNASPGYGIRSDVIRFESDEKAMAGKLRDDVTRLTQVSLSAQQIRYETPNYISLFFCGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQS2</accession>
    <name>A0A0S2DQS2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_05530</name>
        <name evidence="2" type="ORF">GLE_5476</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000010">
        <property type="protein sequence ID" value="OPD64952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949835.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000010.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60817">
        <property type="protein sequence ID" value="ALN60817"/>
        <property type="gene ID" value="GLE_5476"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64952">
        <property type="protein sequence ID" value="OPD64952"/>
        <property type="gene ID" value="BV903_05530"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5476"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5391"/>
    <dbReference type="OrthoDB" id="2184100at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595674" evidence="1">
        <location>
            <begin position="21"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="182" mass="18705" checksum="1FD9C3F16946B6D9" modified="2016-02-17" version="1">MKTQALLVPILLAAAGIASAQTGDNARRELQQAATGDSFSIGDTRFTLAPQAQVSALKTAQAVDAQQVQVGKYQIRLQPSGAKSASKTVAPAKQKMAAAIADTGKPVVVTSTLNVYVADASALDAAVRASGGKLTYSSKVGGNGRIEFGSVQDAMSAMRKIQALAGVKEASPAIIEEENVLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DR75</accession>
    <name>A0A0S2DR75_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9 10">Chromosomal replication initiator protein DnaA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 14" type="primary">dnaA</name>
        <name evidence="15" type="ORF">BV903_04945</name>
        <name evidence="16" type="ORF">FE772_00005</name>
        <name evidence="14" type="ORF">GLE_5339</name>
    </gene>
    <organism evidence="14 17">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">C3</strain>
        </source>
    </reference>
    <reference evidence="15 18" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 18">B25</strain>
        </source>
    </reference>
    <reference evidence="16 19" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 19">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 11">Belongs to the DnaA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000009">
        <property type="protein sequence ID" value="OPD65086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5339"/>
    <dbReference type="EnsemblBacteria" id="ALN60680">
        <property type="protein sequence ID" value="ALN60680"/>
        <property type="gene ID" value="GLE_5339"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65086">
        <property type="protein sequence ID" value="OPD65086"/>
        <property type="gene ID" value="BV903_04945"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5339"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5256"/>
    <dbReference type="OMA" id="REFNPLF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006275">
        <property type="term" value="P:regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06571">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1750.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00377">
        <property type="entry name" value="DnaA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001957">
        <property type="entry name" value="Chromosome_initiator_DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020591">
        <property type="entry name" value="Chromosome_initiator_DnaA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018312">
        <property type="entry name" value="Chromosome_initiator_DnaA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013317">
        <property type="entry name" value="DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013159">
        <property type="entry name" value="DnaA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024633">
        <property type="entry name" value="DnaA_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038454">
        <property type="entry name" value="DnaA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30050:SF2">
        <property type="entry name" value="PTHR30050:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00308">
        <property type="entry name" value="Bac_DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08299">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11638">
        <property type="entry name" value="DnaA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00051">
        <property type="entry name" value="DNAA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00760">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="SSF48295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00362">
        <property type="entry name" value="DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01008">
        <property type="entry name" value="DNAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 9 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="12">
        <location>
            <begin position="177"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_DnaA_C" evidence="13">
        <location>
            <begin position="388"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="185"/>
            <end position="192"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN60680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OPD65086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QCW24287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="480" mass="53868" checksum="C7386D8A0C4E5C4C" modified="2016-02-17" version="1">MSASCVGPLSSVAGRSAAAADRITHKEDTLQMEAWPRCLERLEAEFPVEDVHTWLKPLQATQRDSKTVLYAPNAFVVEHVRERYLARIRELLSYFAGSEDVSLEVGSLPRSPASTQPLPLETTSVVRQAPAAVAAPVEPFQGNLDTHYTFDNFVEGRSNQLGRAAAWQAAQKPGERAHNPLLLYGGTGLGKTHLMFAAGNAMRDANPAMRVMYLRSEQFFSAMMKALQDKTMDAFKRQFQRVDALLIDDIQFFAGKDRTQEEFFHTFNALFDGKQQIILTCDRYPREVEGLEPRLKSRLAWGLSVAIEPPDFETRAQIVISKAKERGAAIPEEVAFLLAKKMRSNVRDLEGALNTLTARANFTGRAITAEFAQETLRDLLRAQQQAIGIPNIQKTVADYYGLQIKDLLSKRRTRSLARPRQVAMALTKELTEHSLPEIGDAFAGRDHTTVLHACRQIRTLMETDGKLREDWDKLIRKLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAD5</accession>
    <name>A0A0S2DAD5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55504">
        <property type="protein sequence ID" value="ALN55504"/>
        <property type="gene ID" value="GLE_0145"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0145"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.147"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594710" evidence="1">
        <location>
            <begin position="30"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="54" mass="5589" checksum="633C3C365CC38FF6" modified="2016-02-17" version="1">MKLFRSKRFKLLALSALFAAGLGFGAAQAGATQECFPSDNCPHGAWVGGCCDPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAF8</accession>
    <name>A0A0S2DAF8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">4'-phosphopantetheinyl transferase</fullName>
            <ecNumber evidence="4">2.7.8.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">sfp</name>
        <name evidence="4" type="ORF">GLE_0179</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.8.-" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945854.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0179"/>
    <dbReference type="EnsemblBacteria" id="ALN55538">
        <property type="protein sequence ID" value="ALN55538"/>
        <property type="gene ID" value="GLE_0179"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0179"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.181"/>
    <dbReference type="OMA" id="ARWHLHE"/>
    <dbReference type="OrthoDB" id="1542506at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="SSF56214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACPS" evidence="3">
        <location>
            <begin position="83"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN55538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="195" mass="21612" checksum="18D35F594258832C" modified="2016-02-17" version="1">MSLSAGSTPPAAAPRWTWLPHPHGEAAEPHARAWLAAELGDAGLQLVRDARQRPHLQPPHQGWDCNWSHSGERLLVALARGARVGVDLERLQRRPRALEIAQRYFTAREADWLAAQADRDLAFLRLWCAKEAVLKAHGHGLSFGLHRLRFEADDSSLRLVECDAELGAAQAWRLQEIAPGPGYLGALAWRPELGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAI1</accession>
    <name>A0A0S2DAI1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0195</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55554">
        <property type="protein sequence ID" value="ALN55554"/>
        <property type="gene ID" value="GLE_0195"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0195"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.197"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="41" mass="4942" checksum="506E983E6EE52451" modified="2016-02-17" version="1">MAASLWRRPRHRAIPGCWRDYAFARRHRTVARYVQRLGFVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAT2</accession>
    <name>A0A0S2DAT2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_02175</name>
        <name evidence="1" type="ORF">GLE_0268</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945915.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0268"/>
    <dbReference type="EnsemblBacteria" id="ALN55626">
        <property type="protein sequence ID" value="ALN55626"/>
        <property type="gene ID" value="GLE_0268"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0268"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.267"/>
    <dbReference type="OMA" id="WQPVEYN"/>
    <dbReference type="OrthoDB" id="597962at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018724">
        <property type="entry name" value="2OG-Fe_dioxygenase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10014">
        <property type="entry name" value="2OG-Fe_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="244" mass="27217" checksum="53393AFAB0E237BE" modified="2016-02-17" version="1">MSALPPSDHEDFARSIRDSGFRFVAGADMRAHLLQHGSLDDWDAFAASWNDLAPDAYLAQVGRHRRRRHAVFHAGRDGTIERQPHQPHYQALSYNALQGDIERWFEPLRQDIADGASLGTVLGFCRDFFSTLAPRTAAWRIELHQFRIEAGPDREGQPTPEGVHRDGVDYVLVLLIDRHNIVSGTTTIHDRDGTELGSFTLTAPLDAALVDDGRVFHGVTAVTPQDPSREAHRDVLVVTFRAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAT5</accession>
    <name>A0A0S2DAT5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF1820 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_02215</name>
        <name evidence="1" type="ORF">GLE_0277</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945920.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0277"/>
    <dbReference type="EnsemblBacteria" id="ALN55635">
        <property type="protein sequence ID" value="ALN55635"/>
        <property type="gene ID" value="GLE_0277"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0277"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.276"/>
    <dbReference type="OMA" id="FPSPIYT"/>
    <dbReference type="OrthoDB" id="1977712at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014949">
        <property type="entry name" value="DUF1820"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08850">
        <property type="entry name" value="DUF1820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028538">
        <property type="entry name" value="DUF1820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="105" mass="11846" checksum="757FB35B8ACF5AAB" modified="2016-02-17" version="1">MSTLYKVTFLNAGKIYELYARKIGAGTLWGFTEVSELVFDLHDGLVVDPTEERLRDEFGNTRVLHLPMQSIVRIEEVERKGQSAIRDAASGERVVTPFPLPAKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBM4</accession>
    <name>A0A0S2DBM4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">VOC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_03290</name>
        <name evidence="2" type="ORF">GLE_0513</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949925.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0513"/>
    <dbReference type="EnsemblBacteria" id="ALN55871">
        <property type="protein sequence ID" value="ALN55871"/>
        <property type="gene ID" value="GLE_0513"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0513"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.508"/>
    <dbReference type="OMA" id="GNMIRIQ"/>
    <dbReference type="OrthoDB" id="1900922at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="4"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="139" mass="15012" checksum="078E2973B0B5B779" modified="2016-02-17" version="1">MNLSIHSSFLPHTDPDASLAFYRDALGFEVRKDVGYQGLRWITVGPAGQPDTAIVLYPPQATPGLTDAEQRAIAEMMAKGSFAMLNLATPDLDGTFAKLQAGDTEIVQEPVDQPYGLRDCAVRDPAGNLIRIQQTPARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC75</accession>
    <name>A0A0S2DC75_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Divalent-cation tolerance protein CutA</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Periplasmic divalent cation tolerance protein CutA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cutA</name>
        <name evidence="3" type="ORF">BV903_19925</name>
        <name evidence="4" type="ORF">FE772_04550</name>
        <name evidence="2" type="ORF">GLE_0772</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CutA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000059">
        <property type="protein sequence ID" value="OPD62155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946288.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000059.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0772"/>
    <dbReference type="EnsemblBacteria" id="ALN56130">
        <property type="protein sequence ID" value="ALN56130"/>
        <property type="gene ID" value="GLE_0772"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62155">
        <property type="protein sequence ID" value="OPD62155"/>
        <property type="gene ID" value="BV903_19925"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0772"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.761"/>
    <dbReference type="OMA" id="VYTTFPD"/>
    <dbReference type="OrthoDB" id="1801957at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010038">
        <property type="term" value="P:response to metal ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004323">
        <property type="entry name" value="Ion_tolerance_CutA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23419">
        <property type="entry name" value="PTHR23419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03091">
        <property type="entry name" value="CutA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="110" mass="12274" checksum="F5F3011AE7E4E702" modified="2016-02-17" version="1">MRSDTLPLLVLTTCPDPASADAIAQALVEEGLAACVTQLPGATSVYRWQGRIERASEIQLLIKTRVTVCAATLQRLAQLHPYELPEMIVVEPRDVSEPYMRWVNEQTPDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCF1</accession>
    <name>A0A0S2DCF1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">ATP:glutamine synthetase adenylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">ATase</fullName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="3">Glutamine synthetase adenylyl-L-tyrosine phosphorylase</fullName>
                <ecNumber evidence="3">2.7.7.89</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="3">Adenylyl removase</fullName>
                <shortName evidence="3">AR</shortName>
                <shortName evidence="3">AT-N</shortName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="3">Glutamine synthetase adenylyl transferase</fullName>
                <ecNumber evidence="3">2.7.7.42</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="3">Adenylyl transferase</fullName>
                <shortName evidence="3">AT</shortName>
                <shortName evidence="3">AT-C</shortName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="3" type="primary">glnE</name>
        <name evidence="6" type="ORF">GLE_0793</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[glutamine synthetase]-L-tyrosine + ATP = [glutamine synthetase]-O(4)-(5'-adenylyl)-L-tyrosine + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:18589"/>
            <dbReference type="Rhea" id="RHEA-COMP:10660"/>
            <dbReference type="Rhea" id="RHEA-COMP:10661"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:83624"/>
            <dbReference type="EC" id="2.7.7.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[glutamine synthetase]-O(4)-(5'-adenylyl)-L-tyrosine + phosphate = [glutamine synthetase]-L-tyrosine + ADP</text>
            <dbReference type="Rhea" id="RHEA:43716"/>
            <dbReference type="Rhea" id="RHEA-COMP:10660"/>
            <dbReference type="Rhea" id="RHEA-COMP:10661"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:83624"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.7.89"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GlnE family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.89" evidence="3"/>
    <dbReference type="EC" id="2.7.7.42" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946302.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0793"/>
    <dbReference type="EnsemblBacteria" id="ALN56151">
        <property type="protein sequence ID" value="ALN56151"/>
        <property type="gene ID" value="GLE_0793"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0793"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.782"/>
    <dbReference type="OMA" id="EFMVQYA"/>
    <dbReference type="OrthoDB" id="427701at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008882">
        <property type="term" value="F:[glutamate-ammonia-ligase] adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047388">
        <property type="term" value="F:[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000820">
        <property type="term" value="P:regulation of glutamine family amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00802">
        <property type="entry name" value="GlnE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023057">
        <property type="entry name" value="GlnE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005190">
        <property type="entry name" value="GlnE_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013546">
        <property type="entry name" value="PII_UdlTrfase/GS_AdlTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30621">
        <property type="entry name" value="PTHR30621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08335">
        <property type="entry name" value="GlnD_UR_UTase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03710">
        <property type="entry name" value="GlnE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GlnE" evidence="4">
        <location>
            <begin position="43"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="GlnD_UR_UTase" evidence="5">
        <location>
            <begin position="304"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="GlnE" evidence="4">
        <location>
            <begin position="555"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="domain" description="GlnD_UR_UTase" evidence="5">
        <location>
            <begin position="822"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="region of interest" description="Adenylyl removase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Adenylyl transferase" evidence="3">
        <location>
            <begin position="451"/>
            <end position="944"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN56151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="944" mass="102175" checksum="E465726BA0982F5B" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCN7</accession>
    <name>A0A0S2DCN7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF58 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0939</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946409.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0939"/>
    <dbReference type="EnsemblBacteria" id="ALN56297">
        <property type="protein sequence ID" value="ALN56297"/>
        <property type="gene ID" value="GLE_0939"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0939"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.926"/>
    <dbReference type="OMA" id="YCDYARL"/>
    <dbReference type="OrthoDB" id="848990at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF58" evidence="1">
        <location>
            <begin position="44"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="298" mass="32111" checksum="D985793E674575EB" modified="2016-02-17" version="1">MSDGVVPSLAELVALRAAVAGRRSARQGRHGVSGQALSPLRGRGMEYAESREYSNGDDARHIDWRLTARTGRAHTKLFQAERERLSLIVADTSPALYFGTRVRFKSVQAARAGAVAAWAAARDGDRIAALRGSLREPPVNPGSGPRGALRVLDAMVRWYARPPAEDAGLEVALDHAARLLRPGSRMVVLAEPGSVAALPQRRWAVLAQHHEVIVLLLTDPIEAAPPQAALPFSHDGQRIELDLGAPAQRQRWHASFVAPVQAALEKLPARGVRVQALSTDAASESWLPLLGRTRPLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCQ2</accession>
    <name>A0A0S2DCQ2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal protein L11 methyltransferase</fullName>
            <shortName evidence="2">L11 Mtase</shortName>
            <ecNumber evidence="2">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 3" type="primary">prmA</name>
        <name evidence="3" type="ORF">GLE_0762</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Methylates ribosomal protein L11.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-lysyl-[protein] + 3 S-adenosyl-L-methionine = 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:54192"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:13826"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the methyltransferase superfamily. PrmA family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0762"/>
    <dbReference type="EnsemblBacteria" id="ALN56120">
        <property type="protein sequence ID" value="ALN56120"/>
        <property type="gene ID" value="GLE_0762"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0762"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.750"/>
    <dbReference type="OMA" id="EFFFIFP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00735">
        <property type="entry name" value="Methyltr_PrmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004498">
        <property type="entry name" value="Ribosomal_PrmA_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000401">
        <property type="entry name" value="RPL11_MTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00406">
        <property type="entry name" value="prmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="317" mass="33857" checksum="B3C27136332A8C7E" modified="2016-02-17" version="1">MAAVFASPRPPMPFLELTLRCSEAEQPRFEAALDDVGALAVTMLDADADSSNERAILEPGVGETPLWQSIVLSALFPHDADALVILAALESFDPELDWSRVGFANVEDQDWERAWMDQYAPLQFGRRTWIVPWNQELPDGADVADAAVVRLDPGLAFGSGTHPTTALCLAWLDTLADAGELAGRRVLDFGCGSGILALAALKLGAAHAVGVDNDPQALIATADNAERNGVAAQLQVHLPPDEPVEAYPVVVANILASALIALADTLAARVAPGGRIALSGILAGQEDEVVARYAEGFEQLQVERLEDWIRVTGVRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD06</accession>
    <name>A0A0S2DD06_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein QmcA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BV903_03905</name>
        <name evidence="7" type="ORF">FE772_05920</name>
        <name evidence="5" type="ORF">GLE_1069</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000007">
        <property type="protein sequence ID" value="OPD65245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946501.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1069"/>
    <dbReference type="EnsemblBacteria" id="ALN56427">
        <property type="protein sequence ID" value="ALN56427"/>
        <property type="gene ID" value="GLE_1069"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65245">
        <property type="protein sequence ID" value="OPD65245"/>
        <property type="gene ID" value="BV903_03905"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1069"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1057"/>
    <dbReference type="OMA" id="TQIRAEM"/>
    <dbReference type="OrthoDB" id="1213601at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018080">
        <property type="entry name" value="Band_7/stomatin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032435">
        <property type="entry name" value="Band_7_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_HflKC_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16200">
        <property type="entry name" value="Band_7_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01270">
        <property type="entry name" value="BAND_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHB" evidence="4">
        <location>
            <begin position="22"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="218"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD65245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW25264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="318" mass="34806" checksum="C1057F6179E14B8B" modified="2016-02-17" version="1">MGAAGSILALVLVFAGVVLLFKTVRMVPQGYQWTVERFGRYTHTMDPGLHFLIPVIYDVGRKINMMEQVLEVPSQDVITKDNAVVKVDGIVFFQVQDAAKAAYEVAQLEIAILNLVMTNIRTAIGSMDLDESLSKRDEINTKVLNAVDAATHPWGLKVNRIELKDIQPPRDLVDSMARQMKAEREKRANILEAEGHRQSEILRAEGDKQAAILEAEGKREAAYREAEARERLAEAEAKATQLVSDAIAAGNVQAINYFVAQKYIEAFKALAQAPNQKFVMMPMESSGVIGSLAGIAELAKDAMAQQAASSARPPRSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD13</accession>
    <name>A0A0S2DD13_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1042</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56400">
        <property type="protein sequence ID" value="ALN56400"/>
        <property type="gene ID" value="GLE_1042"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1042"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1030"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="74" mass="7901" checksum="8FF8B6407BFC9F36" modified="2016-02-17" version="1">MPRSLSRRGDSHMAVWGQSGDSPVRPGSAARKARNGDASSPWKPAILAAGPGWQQRPAPASAERPTRPRPFSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD50</accession>
    <name>A0A0S2DD50_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Channel protein, hemolysin III family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Hemolysin III</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Hemolysin III family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BV903_04095</name>
        <name evidence="9" type="ORF">FE772_06115</name>
        <name evidence="7" type="ORF">GLE_1115</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0073 (Hly-III) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000007">
        <property type="protein sequence ID" value="OPD65276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946534.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000007.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56473">
        <property type="protein sequence ID" value="ALN56473"/>
        <property type="gene ID" value="GLE_1115"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65276">
        <property type="protein sequence ID" value="OPD65276"/>
        <property type="gene ID" value="BV903_04095"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1115"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1101"/>
    <dbReference type="OMA" id="HEVFHSL"/>
    <dbReference type="OrthoDB" id="1659567at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019835">
        <property type="term" value="P:cytolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004254">
        <property type="entry name" value="AdipoR/HlyIII-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005744">
        <property type="entry name" value="Hy-lIII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855">
        <property type="entry name" value="PTHR20855"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03006">
        <property type="entry name" value="HlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01065">
        <property type="entry name" value="hlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN56473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD65276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW25299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="225" mass="24057" checksum="FCF89BBEC44C4FEF" modified="2016-02-17" version="1">MPAAHAPAHGDHSIREEFANALTHGLGATAALAGGAVMITLAALYGDGWQLGSAIVFGISLLLLYIASTLYHAIQHPVAKGRLKVFDHCAIYLLIAGTYTPFTLIGLRGPWGWGLFAAIWGLAAAGIVFKLYYTGRFKLLSTAIYIAMGWLVLVAIKPLLDALDAWALGWLLAGGLCYTLGTVFYHRPSLKYSHAIWHLFVVAGSVCHYIAVLSQVVPSPQALTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD62</accession>
    <name>A0A0S2DD62_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">(2Fe-2S)-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Xanthine dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yagT</name>
        <name evidence="3" type="ORF">FE772_06190</name>
        <name evidence="2" type="ORF">GLE_1131</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946544.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1131"/>
    <dbReference type="EnsemblBacteria" id="ALN56489">
        <property type="protein sequence ID" value="ALN56489"/>
        <property type="gene ID" value="GLE_1131"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1131"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1116"/>
    <dbReference type="OMA" id="MMIDFLH"/>
    <dbReference type="OrthoDB" id="1843415at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="SSF47741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="1">
        <location>
            <begin position="9"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="193" mass="21421" checksum="3DB25978A2AA6688" modified="2016-02-17" version="1">MSQGSLRLIPLTLRINGRDHGPIDVPDDMMLVDVLHEYLGLTGTRFGCGQGVCRACTVIVDDEQGPREVRSCITGAHYFQGKAIRTVEGHAKRGDDGALLELSAVQQAFLDHFSFQCGYCTPGFVNAATVLLERLGKQAARDYQRDEVRALILDALNPHLCRCTGYVRYYQAVEELVLKLPTVRLRTPAEDSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDE9</accession>
    <name>A0A0S2DDE9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4426 domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_06320</name>
        <name evidence="2" type="ORF">GLE_1159</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1159"/>
    <dbReference type="EnsemblBacteria" id="ALN56517">
        <property type="protein sequence ID" value="ALN56517"/>
        <property type="gene ID" value="GLE_1159"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1159"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1144"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025218">
        <property type="entry name" value="DUF4426"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14467">
        <property type="entry name" value="DUF4426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4426" evidence="1">
        <location>
            <begin position="38"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="153" mass="16518" checksum="A3E0EB81212F7F7D" modified="2016-02-17" version="1">MSRRVLAALALALLAGCGRDPSVPPSQGNAAGSETVRQGDVYLHVTAVQTDKLPEQVVRRYGAQRDARTVLVVMSLRLGDGADAKALTAQRVQATATDLLGRKQTLAMREMRDGELVDYVGTAQVAPPDTLRFEVSMDTGHGIHPAKFNRDFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE91</accession>
    <name>A0A0S2DE91_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Calcium-binding EF-hand</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BV903_12755</name>
        <name evidence="4" type="ORF">GLE_1598</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000031">
        <property type="protein sequence ID" value="OPD63583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946910.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1598"/>
    <dbReference type="EnsemblBacteria" id="ALN56955">
        <property type="protein sequence ID" value="ALN56955"/>
        <property type="gene ID" value="GLE_1598"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63583">
        <property type="protein sequence ID" value="OPD63583"/>
        <property type="gene ID" value="BV903_12755"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1598"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1578"/>
    <dbReference type="OMA" id="ERPKWEA"/>
    <dbReference type="OrthoDB" id="1913389at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
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        <property type="match status" value="1"/>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Hernandez I."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
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        <source>
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</entry>
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    <accession>A0A0S2DEL7</accession>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="2">
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        <source>
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        <source>
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    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="358" mass="39646" checksum="722E4E19FC005473" modified="2016-02-17" version="1">MNDPNPDRDAPAPSPADPPPLPPEAHAAYAARVAKIRRFDRPLLALLPVLGGALIGLALRLVFNGEAGSAWAPMLTVFILLAPVAIGAVTVYLAERQQARRLRYHFFAPWLSVTLCMAGTMLFMLEGAICIVLIWPLFAVLASIGGMLMGALCRWAGWSKTPTVYSLAFLPVLLTLFGVGHDEPWRIERVERSVLVQAAPAAVWRQLLDADHIRAAEVDRAWMYRIGVPTPLAGLTHEDAAGLTREVRMGKGIHFRQRSADWQPGRYVQWQYQFAPDSIPPGALDDHVEIGGHYFDLTGTRYTLVPRGAATELRIRMDYRVSTGFNWYAAPLARWLIGDFSDTILQFYRHRAEAAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEL9</accession>
    <name>A0A0S2DEL9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent zinc metalloprotease FtsH</fullName>
            <ecNumber evidence="5">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hflB</name>
        <name evidence="5 10" type="synonym">ftsH</name>
        <name evidence="10" type="ORF">FE772_07905</name>
        <name evidence="9" type="ORF">GLE_1507</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the central section; belongs to the AAA ATPase family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946833.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1507"/>
    <dbReference type="EnsemblBacteria" id="ALN56864">
        <property type="protein sequence ID" value="ALN56864"/>
        <property type="gene ID" value="GLE_1507"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1507"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1488"/>
    <dbReference type="OMA" id="QYGMTER"/>
    <dbReference type="OrthoDB" id="190468at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01458">
        <property type="entry name" value="FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005936">
        <property type="entry name" value="FtsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011546">
        <property type="entry name" value="Pept_M41_FtsH_extracell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06480">
        <property type="entry name" value="FtsH_ext"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="SSF140990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01241">
        <property type="entry name" value="FtsH_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5 10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5 10" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="8">
        <location>
            <begin position="188"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="598"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="419"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="196"/>
            <end position="203"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="418"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="422"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="496"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW25601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="632" mass="69243" checksum="D53E23C3BADAC7D5" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DET6</accession>
    <name>A0A0S2DET6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_08260</name>
        <name evidence="2" type="ORF">GLE_1587</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946900.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56944">
        <property type="protein sequence ID" value="ALN56944"/>
        <property type="gene ID" value="GLE_1587"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1587"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1567"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="123" mass="13271" checksum="7126DE5CF0FCC986" modified="2016-02-17" version="1">MNLPDNALVLPLIMAVSGLPVLVAAVLVARGNLRLINGLDAARLRDPAAAAARFARLLALVAISMFLAALGFYWAHGDYNRILVVTVLLLVSVNGLAATMLIALSRLKRDYRAPRDDPRTGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEX4</accession>
    <name>A0A0S2DEX4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyl-L-citrulline deacetylase</fullName>
            <shortName evidence="2">ACDase</shortName>
            <shortName evidence="2">Acetylcitrulline deacetylase</shortName>
            <ecNumber evidence="2">3.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">argE'</name>
        <name evidence="5" type="ORF">FE772_09420</name>
        <name evidence="4" type="ORF">GLE_1838</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the deacetylation of N-acetyl-L-citrulline to produce L-citrulline. This is a step in an alternative arginine biosynthesis pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + N(2)-acetyl-L-citrulline = acetate + L-citrulline</text>
            <dbReference type="Rhea" id="RHEA:61092"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
            <dbReference type="ChEBI" id="CHEBI:58765"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <text evidence="2">Binds 1 Co(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-arginine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M20A family. N-acetylcitrulline deacetylase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947084.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1838"/>
    <dbReference type="EnsemblBacteria" id="ALN57190">
        <property type="protein sequence ID" value="ALN57190"/>
        <property type="gene ID" value="GLE_1838"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1838"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1809"/>
    <dbReference type="OMA" id="YIVGEPT"/>
    <dbReference type="OrthoDB" id="906744at2"/>
    <dbReference type="UniPathway" id="UPA00068"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019213">
        <property type="term" value="F:deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02236">
        <property type="entry name" value="ACDase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043697">
        <property type="entry name" value="ACDase_ArgE'-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0170">Cobalt</keyword>
    <keyword evidence="1 2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="3">
        <location>
            <begin position="160"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="364" mass="38691" checksum="C35BF9B194AB1099" modified="2016-02-17" version="1">MLPDVLKHLQALVSYDTRNPPREIGTGGIFDYLRSQLPGFRIEVTDFGAGAVSMLAVRGNPRRLFNVHLDTVPSSEAWSADPHTLRVTEDRAIGLGACDIKGAAACLLAAAAVTDGDAAFLFSTDEEANDARCIAGFLATSHGFSEAIVAEPTQCEAVLAHRGISSVLLKFRGVAGHASGANAMQASALHQAVRWGGKALDYVEAQSHQRFGGLTGLRFNIGRVEGGIKANMIAPSAELRFGFRPLPSQSIDGLHELFGTLSDAGIIERYEETFRGPPLPGGDVADAENRRLEARDLADALNLPIGNAVDFWTEASLFSAGGLTAIVYGPGDIAQAHTADEWVALDQLERYARSVARIIGSQAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF66</accession>
    <name>A0A0S2DF66_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="12">TonB family C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLE_1868</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TonB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1868"/>
    <dbReference type="EnsemblBacteria" id="ALN57220">
        <property type="protein sequence ID" value="ALN57220"/>
        <property type="gene ID" value="GLE_1868"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1868"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1839"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043709">
        <property type="term" value="P:cell adhesion involved in single-species biofilm formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023829">
        <property type="entry name" value="PGA_PgaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13994">
        <property type="entry name" value="PgaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03940">
        <property type="entry name" value="PGA_PgaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="84"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="244"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_C" evidence="11">
        <location>
            <begin position="362"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="276"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="287"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="330"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN57220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="442" mass="47133" checksum="04C2F63AE3BBAF44" modified="2016-02-17" version="1">MSNGNERTPGTGGDNPNGDNNGSAAPPRGAGTGRAADGFSRPSHSTAAPPAAPPKPEDTAKPVSHKHDSRLIQKPAMQHPLPRTLWGVVTGAFWLVYLYLWMPVLTLVLWLLGIRTVASELYLRTHEVDPFLMLILPATAAAVVALLLIWAEYNRWRFAGRDGERRSRLADVSIDEVAQALGASDEVAQALNAGRISVLHMDPNHAVPLGVTAVTPTPPAQHPFPPLAPKPRFTRTAAAPGNTWLLAVALGAIALVIGVLIVVSHGYRQIETSAPVHGLEGAPGLDRPALGDDEEGSRFVDPAAKAGDDAAADDAAPAASDPQTATAQQTREAKKRRDNEARARRKPAADNARPKPLPGFSPKPAYPLDALRQWEGGLVTLRVQVSAQGEATKVEISRRSGYRALDRAAVDTVRRWKFSPAVRDGKPVAAVVFVPVEFKPGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFF2</accession>
    <name>A0A0S2DFF2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1866</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947106.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57218">
        <property type="protein sequence ID" value="ALN57218"/>
        <property type="gene ID" value="GLE_1866"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1866"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1837"/>
    <dbReference type="OrthoDB" id="2018531at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027961">
        <property type="entry name" value="DUF4442"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14539">
        <property type="entry name" value="DUF4442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="174" mass="18766" checksum="4AF610018EA5E01E" modified="2016-02-17" version="1">MRSWHERLLGDLSGSLRRLAFLPEAWRYRIVSTALGRQSRYFRTHRLRIVHIAPGRISIGAANHRSLRNRAGALHAMAASVAGEYAAALVVAQHLPRGARLLVKSVHADFRAPLRGDVQAQACIDPEQIGAACAGAGGRLRVAMKVIDATGKAPVRGHVDVVWSSPSSTQDTGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFI2</accession>
    <name>A0A0S2DFI2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phospholipase C</fullName>
            <ecNumber evidence="2">3.1.4.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">plcN</name>
        <name evidence="5" type="ORF">GLE_1923</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial phospholipase C family.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.3" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1923"/>
    <dbReference type="EnsemblBacteria" id="ALN57274">
        <property type="protein sequence ID" value="ALN57274"/>
        <property type="gene ID" value="GLE_1923"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1923"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1889"/>
    <dbReference type="OMA" id="GYYCSLH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034480">
        <property type="term" value="F:phosphatidylcholine phospholipase C activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017767">
        <property type="entry name" value="Bact_PC-PLC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007312">
        <property type="entry name" value="Phosphoesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008475">
        <property type="entry name" value="PLipase_C_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956">
        <property type="entry name" value="PTHR31956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05506">
        <property type="entry name" value="DUF756"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04185">
        <property type="entry name" value="Phosphoesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03396">
        <property type="entry name" value="PC_PLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF756" evidence="4">
        <location>
            <begin position="498"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="domain" description="DUF756" evidence="4">
        <location>
            <begin position="598"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="480"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="695" mass="75570" checksum="5404659038833695" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFL7</accession>
    <name>A0A0S2DFL7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Asparagine synthase</fullName>
            <ecNumber evidence="8">6.3.5.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">asnB</name>
        <name evidence="8" type="ORF">GLE_1791</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asparagine synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.4" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1791"/>
    <dbReference type="EnsemblBacteria" id="ALN57144">
        <property type="protein sequence ID" value="ALN57144"/>
        <property type="gene ID" value="GLE_1791"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1791"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1764"/>
    <dbReference type="OMA" id="MVHQVES"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_Synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00712">
        <property type="entry name" value="AsnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006426">
        <property type="entry name" value="Asn_synth_AEB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033738">
        <property type="entry name" value="AsnB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001589">
        <property type="entry name" value="Asn_synthetase_glu-h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01536">
        <property type="entry name" value="asn_synth_AEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="8" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="7">
        <location>
            <begin position="2"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for beta-aspartyl-AMP intermediate formation" evidence="6">
        <location>
            <position position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN57144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="669" mass="74301" checksum="5D1D951A348F4B4A" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFM0</accession>
    <name>A0A0S2DFM0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">L-sorbosone dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.-</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Sorbosone dehydrogenase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_10600</name>
        <name evidence="2" type="ORF">GLE_2096</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW26050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947275.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57446">
        <property type="protein sequence ID" value="ALN57446"/>
        <property type="gene ID" value="GLE_2096"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2096"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2060"/>
    <dbReference type="OMA" id="GINHHWT"/>
    <dbReference type="OrthoDB" id="1150223at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012938">
        <property type="entry name" value="Glc/Sorbosone_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07995">
        <property type="entry name" value="GSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GSDH" evidence="1">
        <location>
            <begin position="251"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="442" mass="46637" checksum="F392719DD16CDE19" modified="2016-02-17" version="1">MAAALDRGCRWIAAATLALACAGCGERAALQVADGTGPAPQLPKPNPTMIPTVDIAPAVGWRDGARPTPAPGLAVNAFAQGLDHPRWLYVLPNGDVLVAESNAPRSEHKPSGIKAWFAARLMKKAGAGVASADRISLLRDADGDGTAETRTVFLQGLHSPFGMALIGDRLYVANADAVWRFPYRDGETAIAAAGEKVTELPAGINHHWTKNLIANAAGDRLYVTVGSNSNVGENGLAAEEGRAAIWELDPASGEKRLFATGLRNPNGLAWEPQTGALWTAVNERDEIGSDLVPDYITSVEDGAFYGWPYSYYGQHVDARVQPPRPDLVAKAKAPDYALGPHTASLGIAFSDRAKLPAAYAQGLFVGQHGSWNRKPKSGYKVIFVPFANGTPAGPPRDVLSGFLDASEQAQGRPVDVRIDARGALLVSDDVGNTVWRVTAAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFU3</accession>
    <name>A0A0S2DFU3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polymer-forming cytoskeletal protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_09965</name>
        <name evidence="2" type="ORF">GLE_1961</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947172.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1961"/>
    <dbReference type="EnsemblBacteria" id="ALN57312">
        <property type="protein sequence ID" value="ALN57312"/>
        <property type="gene ID" value="GLE_1961"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1961"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1926"/>
    <dbReference type="OMA" id="IDIRKPG"/>
    <dbReference type="OrthoDB" id="1763241at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007607">
        <property type="entry name" value="BacA/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35024">
        <property type="entry name" value="PTHR35024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04519">
        <property type="entry name" value="Bactofilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="204" mass="21147" checksum="C2BDAB5372D92285" modified="2016-02-17" version="1">MAIFNQPAPPKRDTPLPPLQPETALKKEPDTANEFSFGQPSAPTPAPISAPAQAPAPQQRPAEARETAKESLIAADLTIEGKIHGAGHIRIAGRFKGDVQVDGDLTVELGAKVNGGVRARKVVIAGELEGNIDSAQRVELLESGVVVGDVKAGTVTVAAGARVRGQVEFGWEDSGKSVARNDKSDKNDNGKSDKGGKAETGADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFV7</accession>
    <name>A0A0S2DFV7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2067</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2067"/>
    <dbReference type="EnsemblBacteria" id="ALN57417">
        <property type="protein sequence ID" value="ALN57417"/>
        <property type="gene ID" value="GLE_2067"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2067"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2032"/>
    <dbReference type="OMA" id="EYKGAWD"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010499">
        <property type="entry name" value="AraC_E-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029442">
        <property type="entry name" value="GyrI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06445">
        <property type="entry name" value="GyrI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00871">
        <property type="entry name" value="AraC_E_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="15"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="287" mass="31791" checksum="5711CFEFD139B92F" modified="2016-02-17" version="1">MVRSTTFEHYSARIEKVVAFMAQRLDQPLTLAQLAEAGHFSPYHFHRVYRGLMGETIANTQRRLRLHRAAHELLHGHDGIAAIARRAGYASVAAFTRAFAAAYEQPPAAFRKRRAAPPALARADFDPTLESLMYSAQISTLAPHRAVALPHRGDYNGIGAQFERLYGWAGALGLLAAQPPRAFGIYYDSPADTPAERLRSDACLAVPPQTAPGEGMRWIEIAGGRHAVVIHTGPYSELQRAYDWLFCQWLPASGEEAGDAPVYEEYLNDSRSLPPEQWQTSICLPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG44</accession>
    <name>A0A0S2DG44_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2257</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57606">
        <property type="protein sequence ID" value="ALN57606"/>
        <property type="gene ID" value="GLE_2257"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2257"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2222"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="37" mass="4339" checksum="9F72A97C66A0BDDB" modified="2016-02-17" version="1">MSARCATTTPRHATQQPRKDRANQQRKRVSLSREESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG61</accession>
    <name>A0A0S2DG61_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2198</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57547">
        <property type="protein sequence ID" value="ALN57547"/>
        <property type="gene ID" value="GLE_2198"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2198"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2160"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="76" mass="8671" checksum="0C3960BD28B2FE79" modified="2016-02-17" version="1">MRAEAMKHLCCCATYAEMKPAHLLMSPRNLRVRALVCRVRRSALVSPRTLRERARSASRPVRNSKRGKAHERGDTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGH6</accession>
    <name>A0A0S2DGH6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2151</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57501">
        <property type="protein sequence ID" value="ALN57501"/>
        <property type="gene ID" value="GLE_2151"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2151"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="75" mass="7958" checksum="725C44D61B745F47" modified="2016-02-17" version="1">MGDADAVPAALSGGSFLVGAAREPRLRQRNAGAQWRSWVSIRRRPNAAWCCCLRRCLVGAVAACAAPTGSFGQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGR5</accession>
    <name>A0A0S2DGR5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FAD-binding oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Oxidoreductase, FAD binding</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_12400</name>
        <name evidence="3" type="ORF">GLE_2482</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947571.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2482"/>
    <dbReference type="EnsemblBacteria" id="ALN57831">
        <property type="protein sequence ID" value="ALN57831"/>
        <property type="gene ID" value="GLE_2482"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2482"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2444"/>
    <dbReference type="OrthoDB" id="482388at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016899">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010031">
        <property type="entry name" value="FAD_lactone_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762">
        <property type="entry name" value="PTHR43762"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="2">
        <location>
            <begin position="22"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="468" mass="51433" checksum="87BEBB0E2F0C5BD0" modified="2016-02-17" version="1">MSIAALPCAPPLETLNDVHARLNPTQAQVLRPDSVEAACAAVRACARAGQPLIAAGARHAMGGQQFLSGGRVLDTSALCGVLGFDDARGLLTVQAGIRWPALLAWLASSPDNRGGWTIRQKQTGADEFSLGGALASNIHGRGLSYAPFVEDVEDLTLIDAQGELIHASRQQRPELFALVAGGYGLFGIVVALTLRLTPRQVLRREVALARVGELPSAFARAIADGCTYGDFQFAIDPASDDFLDLGVLSCYRPAPDAVASAPRHLQADDFARLLLLAHHQPTRAFDEYADFYLATHGQHYASDAQQTGVYLDGYHAAVDRSLGHCGSEMISELYVPRAALAGFMARAAHSLRRHRAQPIYGTVRLIERDPTSVLAWAREDWACVIFNLHLRHDAEGIDDGARAFRALIDDALWFDGSFYLTYHRWATRAQLEAAHPRLREFLRAKREFDPQQRWQSDWYRHHLAVMQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH65</accession>
    <name>A0A0S2DH65_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-aminomuconate deaminase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_18785</name>
        <name evidence="1" type="ORF">GLE_2674</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000052">
        <property type="protein sequence ID" value="OPD62401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947724.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000052.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2674"/>
    <dbReference type="EnsemblBacteria" id="ALN58022">
        <property type="protein sequence ID" value="ALN58022"/>
        <property type="gene ID" value="GLE_2674"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62401">
        <property type="protein sequence ID" value="OPD62401"/>
        <property type="gene ID" value="BV903_18785"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2674"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2633"/>
    <dbReference type="OMA" id="FLVNMND"/>
    <dbReference type="OrthoDB" id="1850770at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD62401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="145" mass="15687" checksum="12DA19A5EF1C5335" modified="2016-02-17" version="1">MSGAVRTGNAPRPVGSYPHARRAGDLLFLSGVGPRDAASNAVPGNVHDAQGRLIAYDIELQTRSVFANVRAVLEASGATWDDLVDVTVYLTDMARDFAAYNALWAEYFPDIDRAPCRTTLGITALPTPIAIELKCVARLRDAERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH99</accession>
    <name>A0A0S2DH99_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Peptidase S8</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Subtilisin N-terminal region/peptidase, families S8 and S53</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FE772_13225</name>
        <name evidence="9" type="ORF">GLE_2637</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947695.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2637"/>
    <dbReference type="EnsemblBacteria" id="ALN57985">
        <property type="protein sequence ID" value="ALN57985"/>
        <property type="gene ID" value="GLE_2637"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2637"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2596"/>
    <dbReference type="OMA" id="YPAGMAT"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07477">
        <property type="entry name" value="Peptidases_S8_Subtilisin_subset"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034202">
        <property type="entry name" value="Subtilisin_Carlsberg-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242443" evidence="6">
        <location>
            <begin position="26"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="7">
        <location>
            <begin position="155"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="8">
        <location>
            <begin position="382"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="7">
        <location>
            <begin position="471"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN57985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW26481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="551" mass="56044" checksum="56E5D87F88E00E17" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHG3</accession>
    <name>A0A0S2DHG3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative lysyl-tRNA synthetase</fullName>
            <ecNumber evidence="3">6.1.1.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2755</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.1.1.6" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947788.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2755"/>
    <dbReference type="EnsemblBacteria" id="ALN58103">
        <property type="protein sequence ID" value="ALN58103"/>
        <property type="gene ID" value="GLE_2755"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2755"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2712"/>
    <dbReference type="OMA" id="EWYRPGF"/>
    <dbReference type="OrthoDB" id="63621at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004824">
        <property type="term" value="F:lysine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006430">
        <property type="term" value="P:lysyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004525">
        <property type="entry name" value="EpmA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018149">
        <property type="entry name" value="Lys-tRNA-synth_II_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00982">
        <property type="entry name" value="TRNASYNTHLYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00462">
        <property type="entry name" value="genX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="2">
        <location>
            <begin position="19"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="331" mass="36408" checksum="9F76C7F83F3F8C2F" modified="2016-02-17" version="1">MSAATADAGWRPSAGFEALRLRARLNASVRAFFAERGATEVETPVLSRAGNTDPNIASFALEFSGRTDGAPRTRWLRTSPEFPLKRLLAAGFGDCYELGRVFRDGEAGGRHNPEFTMLEWYRLGWDHRRLIGETAALVRAALALVGREASLREVAYRDLYRERLGLDPFTADEAQLRAALGDVVIDPDGLNRDDWLDLLMTHRLQPQFGRDEMLAVRDYPASQCALARVREDGDGFAVAERFELYLGSLELANGYHELADAAEQGARFDRDRGVRAQRGAASPPRDEALLAALASGFPDCAGVALGMDRLLMAMLDTARIADVLAFDFTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHH5</accession>
    <name>A0A0S2DHH5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ImpE protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">ImpE/SciE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_00070</name>
        <name evidence="1" type="ORF">GLE_2575</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000001">
        <property type="protein sequence ID" value="OPD65947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947648.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2575"/>
    <dbReference type="EnsemblBacteria" id="ALN57924">
        <property type="protein sequence ID" value="ALN57924"/>
        <property type="gene ID" value="GLE_2575"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65947">
        <property type="protein sequence ID" value="OPD65947"/>
        <property type="gene ID" value="BV903_00070"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2575"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2534"/>
    <dbReference type="OMA" id="CEFICAG"/>
    <dbReference type="OrthoDB" id="977924at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009211">
        <property type="entry name" value="TagJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07024">
        <property type="entry name" value="ImpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029288">
        <property type="entry name" value="SciE_ImpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD65947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="280" mass="30747" checksum="960C5C370B077201" modified="2016-02-17" version="1">MIRTVSQSQQECSSLLKRGEFDLALRSAMEWAKQHPADAELRIGLFQLLAASGQWSRAREQLQLSARLDAGHGDLAAAYSRVLDAELEREQVMSGQMMPLLLGQAGQWQHDLLLALRQDSQGLAAEAAQRREVALAQAEAAAGEIDGVAFQWLCDADPRFGPCLEVVLETGYAWIAFAQLSEVVLDAPVSLRDLLWQPATLVWRNGDAVAGLVPCRYPGSEHSEHIALRLGRRTDWSGDAAAARGLGQRMLLSDRGEHPLLEIRRIRFDPPPGEAAAWPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHM7</accession>
    <name>A0A0S2DHM7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid adenylation domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_2557</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2557"/>
    <dbReference type="EnsemblBacteria" id="ALN57906">
        <property type="protein sequence ID" value="ALN57906"/>
        <property type="gene ID" value="GLE_2557"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2557"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2517"/>
    <dbReference type="OMA" id="NANMISE"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043604">
        <property type="term" value="P:amide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="1011"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="1082"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="2145"/>
            <end position="2220"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1046"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1117"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="2180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="2241" mass="242191" checksum="499D3EB71186E966" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHZ4</accession>
    <name>A0A0S2DHZ4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SlyX family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2702</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2702"/>
    <dbReference type="EnsemblBacteria" id="ALN58050">
        <property type="protein sequence ID" value="ALN58050"/>
        <property type="gene ID" value="GLE_2702"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2702"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2661"/>
    <dbReference type="OMA" id="NAGMIGH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007236">
        <property type="entry name" value="SlyX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36508">
        <property type="entry name" value="PTHR36508"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04102">
        <property type="entry name" value="SlyX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="10"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="77" mass="8485" checksum="1C8C9419A2EC3C83" modified="2016-02-17" version="1">MSEDPIQQRLVDLETRLAFQEHALTELSDALAAARSEEARNALLLHRALEEIKHLRAAFAASPLTGDASSEPPPPHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI19</accession>
    <name>A0A0S2DI19_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_06155</name>
        <name evidence="5" type="ORF">D9T17_16070</name>
        <name evidence="4" type="ORF">FE772_13985</name>
        <name evidence="2" type="ORF">GLE_2800</name>
    </gene>
    <organism evidence="2 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">C3</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 9" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000011">
        <property type="protein sequence ID" value="OPD64790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000040">
        <property type="protein sequence ID" value="ROU05939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947823.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58148">
        <property type="protein sequence ID" value="ALN58148"/>
        <property type="gene ID" value="GLE_2800"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64790">
        <property type="protein sequence ID" value="OPD64790"/>
        <property type="gene ID" value="BV903_06155"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2800"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2757"/>
    <dbReference type="OrthoDB" id="1961490at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU05939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="178" mass="20371" checksum="6B1F26C41A71BC97" modified="2016-02-17" version="1">MNSQDQQLRAGTDASSQTLDEVRRAQQRNLLSSPSHPQHDLFSQVRVCLDRQDAARQFSPGERDNLAGALLLEATRERQRVDGVAFSQDGKRAFAIEGEADSPTRRISFVDTEQAAQQSLQRSSEQFAQLAREQDVRDQQRQAERERDNERQRQNPERNDEQQPQQSAAARALTRERD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI54</accession>
    <name>A0A0S2DI54_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Bifunctional chorismate mutase/prephenate dehydratase</fullName>
            <ecNumber evidence="8">4.2.1.51</ecNumber>
            <ecNumber evidence="7">5.4.99.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Chorismate mutase-prephenate dehydratase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">p-protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="24" type="primary">pheA</name>
        <name evidence="25" type="ORF">FE772_14920</name>
        <name evidence="24" type="ORF">GLE_2983</name>
    </gene>
    <organism evidence="24 26">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="24 26" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24 26">C3</strain>
        </source>
    </reference>
    <reference evidence="25 27" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="25 27">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H(+) + prephenate = 3-phenylpyruvate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:21648"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:18005"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="EC" id="4.2.1.51"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>chorismate = prephenate</text>
            <dbReference type="Rhea" id="RHEA:13897"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="EC" id="5.4.99.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-phenylalanine biosynthesis; phenylpyruvate from prephenate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Metabolic intermediate biosynthesis; prephenate biosynthesis; prephenate from chorismate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="4.2.1.51" evidence="8"/>
    <dbReference type="EC" id="5.4.99.5" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947958.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2983"/>
    <dbReference type="EnsemblBacteria" id="ALN58331">
        <property type="protein sequence ID" value="ALN58331"/>
        <property type="gene ID" value="GLE_2983"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2983"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2944"/>
    <dbReference type="OMA" id="PLMIYRE"/>
    <dbReference type="OrthoDB" id="1280729at2"/>
    <dbReference type="UniPathway" id="UPA00120">
        <property type="reaction ID" value="UER00203"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00121">
        <property type="reaction ID" value="UER00345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004106">
        <property type="term" value="F:chorismate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004664">
        <property type="term" value="F:prephenate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046417">
        <property type="term" value="P:chorismate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009094">
        <property type="term" value="P:L-phenylalanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.59.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008242">
        <property type="entry name" value="Chor_mutase/pphenate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036263">
        <property type="entry name" value="Chorismate_II_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036979">
        <property type="entry name" value="CM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002701">
        <property type="entry name" value="CM_II_prokaryot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010957">
        <property type="entry name" value="G/b/e-P-prot_chorismate_mutase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001086">
        <property type="entry name" value="Preph_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018528">
        <property type="entry name" value="Preph_deHydtase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01817">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00800">
        <property type="entry name" value="PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001500">
        <property type="entry name" value="Chor_mut_pdt_Ppr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00830">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48600">
        <property type="entry name" value="SSF48600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01807">
        <property type="entry name" value="CM_P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51168">
        <property type="entry name" value="CHORISMATE_MUT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00857">
        <property type="entry name" value="PREPHENATE_DEHYDR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51171">
        <property type="entry name" value="PREPHENATE_DEHYDR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14 24" id="KW-0413">Isomerase</keyword>
    <keyword evidence="15 25" id="KW-0456">Lyase</keyword>
    <keyword evidence="16" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="13" id="KW-0584">Phenylalanine biosynthesis</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chorismate mutase" evidence="21">
        <location>
            <begin position="51"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Prephenate dehydratase" evidence="22">
        <location>
            <begin position="143"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="23">
        <location>
            <begin position="330"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="site" description="Essential for prephenate dehydratase activity" evidence="19">
        <location>
            <position position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00013147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00014401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00031175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00031520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR001500-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="ALN58331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="QCW26745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="411" mass="44730" checksum="C24AFFCAD951ADC1" modified="2016-02-17" version="1">MTTKSSKTAPAKTKPAAAKTKTAAKTAADKGTSKKKPAGKAEAAVEAAVPAAAVPDLATLRTRIDGIDRHIQQLIAERAQFANQVGKAKGKLAAAVDYYRPEREAQVLRRVVDRNDGPLNDEVLVRLFREIMSACLAQQEPLKIGFLGPEGTHSQQAVYKHFGHSIHGLPLSSIEEVFQEVEAGNADFGVVPVENSTQGTIQSTLDMFLTSKLKISGEVELRVHQHLLSRGGRIEDIERVYSHPQSFAQCKAWLRQYLPKAEKIPVSSNAEAARRARNADDAAAIAGVAAANVYGLRSVAGPIEDRPDNTTRFLVVGRELFSPSGNDRTSLLIFIKDQPGALYNVLSPFAKRGLSMNRIESRPGHTGRWQYAFFVDIGGHVQEDAMREALEELQELAHEVKVLGSYPVAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI84</accession>
    <name>A0A0S2DI84_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cold shock protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">DUF1294 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_14345</name>
        <name evidence="3" type="ORF">GLE_2874</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2874"/>
    <dbReference type="EnsemblBacteria" id="ALN58222">
        <property type="protein sequence ID" value="ALN58222"/>
        <property type="gene ID" value="GLE_2874"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2874"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2836"/>
    <dbReference type="OMA" id="HISAFRG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010718">
        <property type="entry name" value="DUF1294"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
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    </dbReference>
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        <property type="entry name" value="DUF1294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="CSD" evidence="2">
        <location>
            <begin position="2"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="212" mass="22927" checksum="7EBE6A1DF449783B" modified="2016-02-17" version="1">MRLAGRICEWNDDKGFGFVVAHDGGARAFVHVKAFQPGSRRPVLGDLISYRVANDAKGRANAVDVRFAGQRIERHPSPSAGPSPLRRIPRRALGVSALLAVAALAALGWVPAAVPLVQGFFSFASYIAYWSDKDAAGASRRRTPENTLHLLDLLGGWPGALIAQQQFRHKTVKPSFQAKFWGTVLLNLVAVAAAVRLGWARALTDLLLDGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI93</accession>
    <name>A0A0S2DI93_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Beta-lactamase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_13795</name>
        <name evidence="3" type="ORF">GLE_2761</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947794.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2761"/>
    <dbReference type="EnsemblBacteria" id="ALN58109">
        <property type="protein sequence ID" value="ALN58109"/>
        <property type="gene ID" value="GLE_2761"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2761"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2718"/>
    <dbReference type="OMA" id="GFQCMMV"/>
    <dbReference type="OrthoDB" id="537440at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242150" evidence="1">
        <location>
            <begin position="22"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="67"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="529" mass="55581" checksum="CBF93C6EAFDFE566" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIB2</accession>
    <name>A0A0S2DIB2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_2920</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polysaccharide synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2920"/>
    <dbReference type="EnsemblBacteria" id="ALN58268">
        <property type="protein sequence ID" value="ALN58268"/>
        <property type="gene ID" value="GLE_2920"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2920"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2882"/>
    <dbReference type="OMA" id="IIIAMPS"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05237">
        <property type="entry name" value="UDP_invert_4-6DH_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003869">
        <property type="entry name" value="Polysac_CapD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02719">
        <property type="entry name" value="Polysacc_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Polysacc_synt_2" evidence="3">
        <location>
            <begin position="285"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="633" mass="69592" checksum="233E3BE4FD44E28A" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DII6</accession>
    <name>A0A0S2DII6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Dipeptidyl carboxypeptidase II</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="12">M3 family metallopeptidase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="10">Peptidyl-dipeptidase dcp</fullName>
            <ecNumber evidence="10">3.4.15.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">dcp</name>
        <name evidence="11" type="ORF">BV903_22135</name>
        <name evidence="12" type="ORF">FE772_15405</name>
        <name evidence="10" type="ORF">GLE_3090</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">C3</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase M3 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.15.5" evidence="10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000073">
        <property type="protein sequence ID" value="OPD61748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948033.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000073.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3090"/>
    <dbReference type="EnsemblBacteria" id="ALN58437">
        <property type="protein sequence ID" value="ALN58437"/>
        <property type="gene ID" value="GLE_3090"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61748">
        <property type="protein sequence ID" value="OPD61748"/>
        <property type="gene ID" value="BV903_22135"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3090"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3049"/>
    <dbReference type="OMA" id="YMITLVN"/>
    <dbReference type="OrthoDB" id="1935578at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06456">
        <property type="entry name" value="M3A_DCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034005">
        <property type="entry name" value="M3A_DCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024077">
        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43660">
        <property type="entry name" value="PTHR43660"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4 7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595078" evidence="8">
        <location>
            <begin position="22"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M3" evidence="9">
        <location>
            <begin position="275"/>
            <end position="726"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN58437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OPD61748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW26821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="737" mass="81745" checksum="3254170487FBFBD5" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIM7</accession>
    <name>A0A0S2DIM7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Serine O-succinyltransferase</fullName>
            <shortName evidence="2">SST</shortName>
            <ecNumber evidence="2">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">metX</name>
        <name evidence="6" type="ORF">FE772_14160</name>
        <name evidence="5" type="ORF">GLE_2836</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Transfers a succinyl group from succinyl-CoA to L-serine, forming succinyl-L-serine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-serine + succinyl-CoA = CoA + O-succinyl-L-serine</text>
            <dbReference type="Rhea" id="RHEA:52820"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:136856"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-serine: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. MetX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947847.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2836"/>
    <dbReference type="EnsemblBacteria" id="ALN58184">
        <property type="protein sequence ID" value="ALN58184"/>
        <property type="gene ID" value="GLE_2836"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2836"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2794"/>
    <dbReference type="OMA" id="TRFCVVS"/>
    <dbReference type="OrthoDB" id="536745at2"/>
    <dbReference type="UniPathway" id="UPA00136">
        <property type="reaction ID" value="UER00199"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016750">
        <property type="term" value="F:O-succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00296">
        <property type="entry name" value="MetX_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008220">
        <property type="entry name" value="HAT_MetX-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268">
        <property type="entry name" value="PTHR32268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000443">
        <property type="entry name" value="Homoser_Ac_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01392">
        <property type="entry name" value="homoserO_Ac_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="46"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Important for substrate specificity" evidence="2">
        <location>
            <begin position="52"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2 3">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <feature type="active site" evidence="2 3">
        <location>
            <position position="324"/>
        </location>
    </feature>
    <feature type="active site" evidence="2 3">
        <location>
            <position position="357"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="358"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for acyl-CoA specificity" evidence="2">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000443-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW26631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="386" mass="42255" checksum="1BD060A603B949B4" modified="2016-02-17" version="1">MTEFIPPGTRHIDLPSPFPMKRGGALTGARIAYETWGELNRQRDNAILIVTGLSPDAHAAANPGNPEPGWWEAMLGPGKPIDSDRWFVICVNSLGSCKGSTGPASLDAARGEPYRLEFPELSVEDGADAAAHVVRALGIARLACVIGNSMGGMTALALLIRHPGLARAHINISGAARALPFSIAIRSLQREAIRLDPKWNQGRYDETDYPESGMRMARKLGVITYRSALEWDGRFGRVRLDSDRLDEEPFGLEFEVESYLEGHARRFVRRFDPNCYLYLSRSMDWFDIGDYCNDGDGLDNDEQVLRGLASIRIEKALAIGVHTDILFPLQQQREIADGLRAGGADARFLPLESPQGHDAFLVDIGRFGPAVAGFLADLPTGVESVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIR8</accession>
    <name>A0A0S2DIR8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD dependent oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">FAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_06125</name>
        <name evidence="3" type="ORF">GLE_2795</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000011">
        <property type="protein sequence ID" value="OPD64785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947819.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000011.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2795"/>
    <dbReference type="EnsemblBacteria" id="ALN58143">
        <property type="protein sequence ID" value="ALN58143"/>
        <property type="gene ID" value="GLE_2795"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64785">
        <property type="protein sequence ID" value="OPD64785"/>
        <property type="gene ID" value="BV903_06125"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2795"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2751"/>
    <dbReference type="OMA" id="FAPGYIG"/>
    <dbReference type="OrthoDB" id="1770293at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="FAD_binding_3" evidence="2">
        <location>
            <begin position="9"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD64785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="384" mass="41819" checksum="7AFD4FD445369EF3" modified="2016-02-17" version="1">MLTDTARFDCDLVVVGASFAGAACALAAARAGLRVVVLERKRDPGDKLRTTGIVVKEAAEQTWLSRAPDSCVHRVERVRLYSPNLRSMALSAPGYYFLTTDTPRLMRWLAQELQRHGVDLRLGASFTQAERDGEGWRIEGVGRARFLVGADGAKSRVAERTGLGRTHEFLYGIEYEFPGASLPESGALHCFVSKRYAPGYIGWVAQNPTGVQAGLALRHDPERARVPDIDGFLARVRDAVGLAPDLQPAATRAGLIPCGGPVFPLARDGAMLTGDAAGIVSPVTAGGIHSAWAHGETLGQAIALHARGVGPAPESIAEDAAPRFRRKRALRWAFDRFQFDWPFDLLLNSTPLRWAAEQVYFHKRGLSEEEIQADAARSRASEHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIV1</accession>
    <name>A0A0S2DIV1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58571">
        <property type="protein sequence ID" value="ALN58571"/>
        <property type="gene ID" value="GLE_3225"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3225"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3179"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="37" mass="3962" checksum="886EB2E73D57FD1D" modified="2016-02-17" version="1">MSRSLRARSVAVRRASAQAGRLQAGLLQAGLPEVDLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ22</accession>
    <name>A0A0S2DJ22_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipoprotein signal peptidase</fullName>
            <ecNumber evidence="6">3.4.23.36</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Prolipoprotein signal peptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Signal peptidase II</fullName>
            <shortName evidence="6">SPase II</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">lspA</name>
        <name evidence="10" type="ORF">FE772_16265</name>
        <name evidence="9" type="ORF">GLE_3285</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">This protein specifically catalyzes the removal of signal peptides from prolipoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>Release of signal peptides from bacterial membrane prolipoproteins. Hydrolyzes -Xaa-Yaa-Zaa-|-(S,diacylglyceryl)Cys-, in which Xaa is hydrophobic (preferably Leu), and Yaa (Ala or Ser) and Zaa (Gly or Ala) have small, neutral side chains.</text>
            <dbReference type="EC" id="3.4.23.36"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Protein modification; lipoprotein biosynthesis (signal peptide cleavage).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 8">Belongs to the peptidase A8 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.36" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948179.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3285"/>
    <dbReference type="EnsemblBacteria" id="ALN58631">
        <property type="protein sequence ID" value="ALN58631"/>
        <property type="gene ID" value="GLE_3285"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3285"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3237"/>
    <dbReference type="OMA" id="NRWYFPA"/>
    <dbReference type="OrthoDB" id="1575081at2"/>
    <dbReference type="UniPathway" id="UPA00665"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00161">
        <property type="entry name" value="LspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001872">
        <property type="entry name" value="Peptidase_A8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33695">
        <property type="entry name" value="PTHR33695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01252">
        <property type="entry name" value="Peptidase_A8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00781">
        <property type="entry name" value="LIPOSIGPTASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00077">
        <property type="entry name" value="lspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00855">
        <property type="entry name" value="SPASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="2 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN58631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW26957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="164" mass="18306" checksum="ADEBC4B574F73509" modified="2016-02-17" version="1">MTSTPAKNALPWLIVSIVVIALDQWSKNWVLSALPEYTPVVVIEGFWNWYRSYNTGAAFSFLSDAGGWQKYFFLALAVGISGLLARWLARTPRGDWKTALPYALVIGGAIGNVIDRLMHGHVVDFIQWYWRSFYWPSFNIADAAIVGGAIGIAAFGLFSKEKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ85</accession>
    <name>A0A0S2DJ85_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3118</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948057.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3118"/>
    <dbReference type="EnsemblBacteria" id="ALN58465">
        <property type="protein sequence ID" value="ALN58465"/>
        <property type="gene ID" value="GLE_3118"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3118"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3075"/>
    <dbReference type="OMA" id="GTYRERT"/>
    <dbReference type="OrthoDB" id="1268974at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="129"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="251" mass="27230" checksum="409B15C291AB67E2" modified="2016-02-17" version="1">MTAAYRTRHERNATLATHRHREPYAALVLDGDYTEASLDGPLPCAPGTLVLHPAFHAHGDRFGRSGASAINLELSPAATPGVTADPAFAARAWCVHDLNEAREVFERAPRRLAELLACAQPLPAAALPDWQGELLRRMNQDEREIAELARELGVSAEHASRALGRSFGMSPRALRREARWRRALRLLAAPMALADVAAAAGFADQSHLHKVVVAHAGCTPLQLRRQVLAPAECRVEAKIKCVQDPHAARAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJA3</accession>
    <name>A0A0S2DJA3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UDP-3-O-acylglucosamine N-acyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.191</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">lpxD</name>
        <name evidence="7" type="ORF">GLE_3380</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a (3R)-hydroxyacyl-[ACP] + a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine = a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + H(+) + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:53836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="ChEBI" id="CHEBI:137740"/>
            <dbReference type="ChEBI" id="CHEBI:137748"/>
            <dbReference type="EC" id="2.3.1.191"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the transferase hexapeptide repeat family. LpxD subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.191" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948253.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3380"/>
    <dbReference type="EnsemblBacteria" id="ALN58726">
        <property type="protein sequence ID" value="ALN58726"/>
        <property type="gene ID" value="GLE_3380"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3380"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3330"/>
    <dbReference type="OMA" id="QIQIAHN"/>
    <dbReference type="OrthoDB" id="1602061at2"/>
    <dbReference type="UniPathway" id="UPA00973"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016410">
        <property type="term" value="F:N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03352">
        <property type="entry name" value="LbH_LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00523">
        <property type="entry name" value="LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007691">
        <property type="entry name" value="LpxD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020573">
        <property type="entry name" value="UDP_GlcNAc_AcTrfase_non-rep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43378">
        <property type="entry name" value="PTHR43378"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04613">
        <property type="entry name" value="LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01853">
        <property type="entry name" value="lipid_A_lpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 5" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="1 5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4 5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="LpxD" evidence="6">
        <location>
            <begin position="26"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="342" mass="35218" checksum="A9054FF26195A85A" modified="2016-02-17" version="1">MDSPGHTARELAERFALGLHGDGEARVSGVGTLAKAGSAQLAFLANPKYRSQLDASAAGVVVMREQDAAGYAGTALIARDPYSAFAKISALFEPRPERPPGIHASAAIDPSAEVSPAAHVGAFVSIGARSRVEAGAMIGPGCVIGEDCTVGEGCELVARVTLVTRVRLGQRVLIHPGAVLGADGFGLAMDAGRWLKVPQLGGVRIGDDCEIGANTCIDRGAIEDTVLEEDVRLDNQIQIGHNVHIGAHSAMAGCSAAAGSAKIGRYCLIGGGAGVLGHLEVCDKVTVTAMSLVTSSIREPGEYSSGTPLMDNRSWRKNAARFKQLDAIARRTRGSGSGDDGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJB1</accession>
    <name>A0A0S2DJB1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Outer membrane protein assembly factor BamA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">yaeT</name>
        <name evidence="6" type="synonym">bamA</name>
        <name evidence="8" type="ORF">GLE_3379</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the Bam complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the BamA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3379"/>
    <dbReference type="EnsemblBacteria" id="ALN58725">
        <property type="protein sequence ID" value="ALN58725"/>
        <property type="gene ID" value="GLE_3379"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3379"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3329"/>
    <dbReference type="OMA" id="IEWISPM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051205">
        <property type="term" value="P:protein insertion into membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01430">
        <property type="entry name" value="OM_assembly_BamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010827">
        <property type="entry name" value="BamA/TamA_POTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039910">
        <property type="entry name" value="D15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023707">
        <property type="entry name" value="OM_assembly_BamA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034746">
        <property type="entry name" value="POTRA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815">
        <property type="entry name" value="PTHR12815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815:SF23">
        <property type="entry name" value="PTHR12815:SF23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07244">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006076">
        <property type="entry name" value="OM_assembly_OMP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03303">
        <property type="entry name" value="OM_YaeT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51779">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 6" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008995360" description="Outer membrane protein assembly factor BamA" evidence="6">
        <location>
            <begin position="30"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="7">
        <location>
            <begin position="49"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="7">
        <location>
            <begin position="117"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="7">
        <location>
            <begin position="200"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="7">
        <location>
            <begin position="291"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="7">
        <location>
            <begin position="372"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="822" mass="91051" checksum="D67391455BB7DE11" modified="2016-02-17" version="1" precursor="true"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJG0</accession>
    <name>A0A0S2DJG0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Phosphate-binding protein PstS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pstS</name>
        <name evidence="10" type="ORF">BV903_20445</name>
        <name evidence="9" type="ORF">GLE_3313</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">B25</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Part of the ABC transporter complex PstSACB involved in phosphate import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 6">The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the PstS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000062">
        <property type="protein sequence ID" value="OPD62054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3313"/>
    <dbReference type="EnsemblBacteria" id="ALN58659">
        <property type="protein sequence ID" value="ALN58659"/>
        <property type="gene ID" value="GLE_3313"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62054">
        <property type="protein sequence ID" value="OPD62054"/>
        <property type="gene ID" value="BV903_20445"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3313"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3263"/>
    <dbReference type="OMA" id="FPYPVYA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042301">
        <property type="term" value="F:phosphate ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005673">
        <property type="entry name" value="ABC_phos-bd_PstS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002756">
        <property type="entry name" value="PstS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00975">
        <property type="entry name" value="3a0107s03"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594844" description="Phosphate-binding protein PstS" evidence="7">
        <location>
            <begin position="25"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="8">
        <location>
            <begin position="22"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN58659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD62054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="339" mass="36144" checksum="3FE3C63469DF6DB6" modified="2016-02-17" version="1">MFNSRSFRVTALALAAAFAFNAQAADVTGAGASFVYPVMSKWSADYAKATNKKVNYQSIGSGGGIAQIKAATVDFGSSDAPLKPEELAKFGLAQFPSVIGGVVPVVNVPGVASGAMKLDGATLANIFLGKITMWNDPAIVALNGGLKLPEKKITVVHRSDGSGTTFNFVNYLSKISPEWKSSVGEGTAVKWPTGIGGKGNEGVAAYVKQIQGGIGYVELSYALQNKMSYSRLKNADGKFVLPTDETFSAAAASADWANSKDFYLVMTNAPGENSWPITATNFILMYKQPKNAEGAKNAKEFFKWVYANGDAQAKTLDYVPLPDALVKQIETYWQSNMSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJG6</accession>
    <name>A0A0S2DJG6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_16440</name>
        <name evidence="1" type="ORF">GLE_3324</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58670">
        <property type="protein sequence ID" value="ALN58670"/>
        <property type="gene ID" value="GLE_3324"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3324"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3274"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="326" mass="36655" checksum="D63EB3341A75111F" modified="2016-02-17" version="1">MDEPATPPYLWIPGLGPDPDALRRLRERAPRPRKPMGEAWFMGGDRHYYTGLMAGAATDWALSELENALTELTSGPTSFDHLDEWSLWFDYLLPRAQERADETWHLHELLVSAVCVHCLDPALPGRDAEFRRDLLDTLGRALMAPSRWRDGRIVADRVLDPLRDYVYGWTLESGAAFSAICSLALRYLETDAVDAWIGSLLAIDDPLWRAVFVVWLDGAEPLLFEDSQPEQAAHDPMKNIAWDWCWVLRGSVPSPRLDPQARVYAFFPPANVAALAAALRRRLGLDALSQWSDALRAACGESRDPGTALWQFETSALRVAERFGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJN6</accession>
    <name>A0A0S2DJN6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_17045</name>
        <name evidence="1" type="ORF">GLE_3461</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58806">
        <property type="protein sequence ID" value="ALN58806"/>
        <property type="gene ID" value="GLE_3461"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3461"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3409"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="105" mass="12440" checksum="DB13C9A228E4A7D9" modified="2016-02-17" version="1">MNRQPVGWLDITVYWDFYDFPRYILARDGLGLYWIFEGSFDDEADEYRDHFIMKCVGLHRDEALRQFEGRVAIPLGVDRSGYERVALTEVAFDESRRKRIRIGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJU0</accession>
    <name>A0A0S2DJU0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-binding response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">KDP operon transcriptional regulatory protein KdpE</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">kdpE</name>
        <name evidence="6" type="ORF">BV903_09290</name>
        <name evidence="7" type="ORF">FE772_15885</name>
        <name evidence="5" type="ORF">GLE_3197</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000020">
        <property type="protein sequence ID" value="OPD64229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948117.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000020.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3197"/>
    <dbReference type="EnsemblBacteria" id="ALN58543">
        <property type="protein sequence ID" value="ALN58543"/>
        <property type="gene ID" value="GLE_3197"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64229">
        <property type="protein sequence ID" value="OPD64229"/>
        <property type="gene ID" value="BV903_09290"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3197"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3152"/>
    <dbReference type="OMA" id="KARKYEV"/>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="19"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="140"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="140"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD64229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW26898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="243" mass="26670" checksum="1D5C11CF624E295E" modified="2016-02-17" version="1">MTHDHAPHAASPQAAPPARVLVVDDEPQIRKFLDIALRAQGYAVELADTGNAGLESLATRGADLVVLDLGLPDRDGFDVLRELRQWSGVPVILLTVRSSEAEKVAALDGGANDYVTKPFGVQELMARVRALLRAHGPQGETLPVFDDGRLRIDLARREVALDGEPVTLARKEYALLALLFQHAGRVVTQPQLLRELWGPTHQEDTHYLRILVGKLRHKLGDDAAAPRYIATEPGVGLRFIDKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJX2</accession>
    <name>A0A0S2DJX2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase, S54 (Rhomboid) family</fullName>
            <ecNumber evidence="8">3.4.21.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BV903_21500</name>
        <name evidence="8" type="ORF">GLE_3497</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">B25</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000071">
        <property type="protein sequence ID" value="OPD61856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948334.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000071.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3497"/>
    <dbReference type="EnsemblBacteria" id="ALN58842">
        <property type="protein sequence ID" value="ALN58842"/>
        <property type="gene ID" value="GLE_3497"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61856">
        <property type="protein sequence ID" value="OPD61856"/>
        <property type="gene ID" value="BV903_21500"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3497"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3442"/>
    <dbReference type="OrthoDB" id="2053476at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="7">
        <location>
            <begin position="61"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD61856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="242" mass="26684" checksum="55C8D42133521A32" modified="2016-02-17" version="1">MVSRLFSSIPSVTRKLLIANVAVFLLQSIAGASEATRAWPLWFELWPWVPAPYEVDGPGFMPWQLLTSGFMHGGLGHLVFNMLALVMFGASIEHEWGARRYAIYYVVCLLGSALLQLAAATYAIYQGQLILTLGASGAIYGLLLAYGVMFPNRKVTLLPFPIVLKARTLVIVYVVASLFYGVFTTGTGVAHFAHLGGMLVGWLLIRWWRSHPPRGGSGGPRRDPRAEALRARRKASKLRLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJX5</accession>
    <name>A0A0S2DJX5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">ABC transporter, ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_17100</name>
        <name evidence="5" type="ORF">GLE_3471</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948316.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58816">
        <property type="protein sequence ID" value="ALN58816"/>
        <property type="gene ID" value="GLE_3471"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3471"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3418"/>
    <dbReference type="OMA" id="MIEYPIF"/>
    <dbReference type="OrthoDB" id="1833499at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW27097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="297" mass="32586" checksum="F4CF536A681C994C" modified="2016-02-17" version="1">MLTIRDLTKTYANGVRALDGICLDIPRGMFGLLGPNGAGKSSLMRTLATLQEADGGSAVLETDGRRIDVLREKDAVRRLLGYLPQDFGVYPKVSALDLLDHFAVLKGLGERKQRREVVEGLLHQVNLWNVRKQKLGGFSGGMRQRFGIAQALLGDPRLVIVDEPTAGLDPEERNRFLNLLAEIGENVAVILSTHIVEDVTDLCPTMAIVDKGKVLLSGEPNAAIAALTGQVWRRQVPKSELDSYETRFTVLSTRLVGGQPVIHVFSADAPEEGFEPVAPDLEDVYFQRLRKHSRVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK58</accession>
    <name>A0A0S2DK58_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_17415</name>
        <name evidence="2" type="ORF">GLE_3539</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057950196.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3539"/>
    <dbReference type="EnsemblBacteria" id="ALN58883">
        <property type="protein sequence ID" value="ALN58883"/>
        <property type="gene ID" value="GLE_3539"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3539"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3483"/>
    <dbReference type="OMA" id="TRCHIGD"/>
    <dbReference type="OrthoDB" id="1687413at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="168" mass="17863" checksum="D2ED165DC3E0B22D" modified="2016-02-17" version="1">MRIEEETHAQRAQTHALNRAAFGRADEADLVDRLRADGLVRLSLVAVEDDEVVGHILFTRLPTRVDGHEVDAVALAPMAVHPHWQGAGVGSALVREGLARLAREGCEAAIVLGHPDYYPRFGFSAALAAKLASPFAGEAFMALELAEGGLRGEAGEVRYPAAFGIDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK99</accession>
    <name>A0A0S2DK99_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Glucose-1-phosphate thymidylyltransferase</fullName>
            <ecNumber evidence="4 5">2.7.7.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rfbA</name>
        <name evidence="8" type="ORF">BV903_24835</name>
        <name evidence="9" type="ORF">FE772_17920</name>
        <name evidence="7" type="ORF">GLE_3642</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>alpha-D-glucose 1-phosphate + dTTP + H(+) = diphosphate + dTDP-alpha-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:15225"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37568"/>
            <dbReference type="ChEBI" id="CHEBI:57477"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.7.7.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the glucose-1-phosphate thymidylyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.24" evidence="4 5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000100">
        <property type="protein sequence ID" value="OPD61210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948438.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000100.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3642"/>
    <dbReference type="EnsemblBacteria" id="ALN58986">
        <property type="protein sequence ID" value="ALN58986"/>
        <property type="gene ID" value="GLE_3642"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61210">
        <property type="protein sequence ID" value="OPD61210"/>
        <property type="gene ID" value="BV903_24835"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3642"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3586"/>
    <dbReference type="OMA" id="FTWLDTG"/>
    <dbReference type="OrthoDB" id="1004719at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008879">
        <property type="term" value="F:glucose-1-phosphate thymidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045226">
        <property type="term" value="P:extracellular polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02538">
        <property type="entry name" value="G1P_TT_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005907">
        <property type="entry name" value="G1P_thy_trans_s"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43532">
        <property type="entry name" value="PTHR43532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01207">
        <property type="entry name" value="rmlA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="6">
        <location>
            <begin position="4"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD61210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW27228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="294" mass="32544" checksum="15B676ACD1F55C1C" modified="2016-02-17" version="1">MNRKGIILAGGSGTRLYPITQAISKQLLPVYDKPMIYYPLSVLMLAGIREVLVINTPHEQPLFQHLLGDGSQWGMRIEYAVQPSPDGLAQAYLIGRDFVAGEPSCLVLGDNIFHGPGLTAILKRADARREGATVFGYWVSDPERYGVAEFDAEGRVIGLEEKPLKPRSRYAVTGLYFYDGRASDFAAQLKPSARGELEITDLNRKYLDEGSLHLEQLGRGYAWLDTGTHQSLLEASNFIETIETRQGLRICCPEEVAYGNGWIDAGQLTDLARPLIKNGYGQYLLSLIERGPVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKB2</accession>
    <name>A0A0S2DKB2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Carbon starvation family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="12">Carbon starvation protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">cstA</name>
        <name evidence="12" type="ORF">FE772_17870</name>
        <name evidence="11" type="ORF">GLE_3632</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="145" mass="15795" checksum="E0B6181A214AEB5E" modified="2016-02-17" version="1">MIARGRARPAVLRLRGLAAAAIAALILAACSQAPPPTEFPGGIAIPSAATDVREHIDDQLRTMTAYYRFDLPPAQLPALAVALHCRLGDVDHGARAAEPGDPAWYAPRPARAHRRCESRIAHWMYELEVDVSRPDRYTVYLSASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKH2</accession>
    <name>A0A0S2DKH2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10 14">Catalase</fullName>
            <ecNumber evidence="3 10 14">1.11.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">katE</name>
        <name evidence="17" type="ORF">GLE_3692</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Serves to protect cells from the toxic effects of hydrogen peroxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 14">
            <text>2 H2O2 = 2 H2O + O2</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10 12">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the catalase family. HPII subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="3 10 14"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3692"/>
    <dbReference type="EnsemblBacteria" id="ALN59036">
        <property type="protein sequence ID" value="ALN59036"/>
        <property type="gene ID" value="GLE_3692"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3692"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3636"/>
    <dbReference type="OMA" id="VMWQMSD"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03132">
        <property type="entry name" value="GATase1_catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1370.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024708">
        <property type="entry name" value="Catalase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024712">
        <property type="entry name" value="Catalase_clade2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043156">
        <property type="entry name" value="Catalase_clade2_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002226">
        <property type="entry name" value="Catalase_haem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041399">
        <property type="entry name" value="Catalase_large_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42821">
        <property type="entry name" value="PTHR42821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18011">
        <property type="entry name" value="Catalase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038927">
        <property type="entry name" value="Catalase_clade2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="SSF56634"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00437">
        <property type="entry name" value="CATALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00438">
        <property type="entry name" value="CATALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10 13" id="KW-0349">Heme</keyword>
    <keyword evidence="9 10 14" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="8 10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="6 10 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 10 14" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase" evidence="16">
        <location>
            <begin position="20"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="11"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="350"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="354"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="361"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR038927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ALN59036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="679" mass="74374" checksum="5F72595600C91789" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKI0</accession>
    <name>A0A0S2DKI0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UPF0056 membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BV903_16850</name>
        <name evidence="11" type="ORF">D9T17_10190</name>
        <name evidence="10" type="ORF">FE772_17665</name>
        <name evidence="8" type="ORF">GLE_3585</name>
    </gene>
    <organism evidence="8 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 12">C3</strain>
        </source>
    </reference>
    <reference evidence="9 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">OH11</strain>
        </source>
    </reference>
    <reference evidence="10 15" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 15">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the UPF0056 (MarC) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000045">
        <property type="protein sequence ID" value="OPD62762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000023">
        <property type="protein sequence ID" value="ROU07317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948396.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3585"/>
    <dbReference type="EnsemblBacteria" id="ALN58929">
        <property type="protein sequence ID" value="ALN58929"/>
        <property type="gene ID" value="GLE_3585"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62762">
        <property type="protein sequence ID" value="OPD62762"/>
        <property type="gene ID" value="BV903_16850"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3585"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3529"/>
    <dbReference type="OMA" id="IRMIFPQ"/>
    <dbReference type="OrthoDB" id="1323133at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002771">
        <property type="entry name" value="Multi_antbiot-R_MarC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33508">
        <property type="entry name" value="PTHR33508"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01914">
        <property type="entry name" value="MarC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD62762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROU07317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="197" mass="21046" checksum="747716D36DF11664" modified="2016-02-17" version="1">MTIASAALLLFIILDPLGNIPVFLSLLRGLPPKRQRIVLARELLIALGVLMLFLWGGKYALELMHLRQESVSIAGGIVLFLIGIRMIFPPPEGLMGEIPDGEPFIVPMAIPLVAGPSGMAAVMLMGSNDPARLGDWSLALLIAWGATAAILFSATILYKLLGRRALIAIERLMGMLLVAISVQMILDGLGSYLPGPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKS6</accession>
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        </submittedName>
    </protein>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_3816"/>
    <dbReference type="EnsemblBacteria" id="ALN59159">
        <property type="protein sequence ID" value="ALN59159"/>
        <property type="gene ID" value="GLE_3816"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3816"/>
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    <dbReference type="OMA" id="RLWILND"/>
    <dbReference type="OrthoDB" id="2055010at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
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        <property type="entry name" value="GNAT_dom"/>
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        <property type="entry name" value="Acetyltransf_1"/>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="3"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
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            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59159.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW27383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="152" mass="16894" checksum="B218E08ADE069C7B" modified="2016-02-17" version="1">MSLAIRRARSADLDLVAPLFDRYRHFYTQRDDAAVSRAFIGERLQRGDSVLLLAALDGADGAGFVQLYPTFSSVRAARVWVLNDLFVEPRARRRGVARALLDVAAAFARADGAARLELETDHDNAQAQALYDAAGWRRFDGTQRYQLPLAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKV2</accession>
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        <submittedName>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59194">
        <property type="protein sequence ID" value="ALN59194"/>
        <property type="gene ID" value="GLE_3851"/>
    </dbReference>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKY2</accession>
    <name>A0A0S2DKY2_LYSEN</name>
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        </submittedName>
    </protein>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59216.1"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_3873"/>
    <dbReference type="EnsemblBacteria" id="ALN59216">
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        <property type="gene ID" value="GLE_3873"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="39"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59216.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW27419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="194" mass="21286" checksum="28CBEA895AC6926A" modified="2016-02-17" version="1">MTADRDHSAQHEPVETIYNGQWLRMMRRGHWEYAERTHGKGMAVIIIAVTPDDNILFVEQFRVPLNARTIEMPAGLVGDDHAHDTLESAAARELIEETGWEPRRVEVLLTGPTSAGMSSERIAFVRASDLHRVGSGGGVAGEDIVVHEVPRADAPAWLMARQAEGYELDLKLWAGLWMIERNPDGSAAAPSAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKZ3</accession>
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    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
    <gene>
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    <reference evidence="1 2" key="1">
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59242">
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    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3899"/>
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="44" mass="4891" checksum="984D23E938624807" modified="2016-02-17" version="1">MWGRVGFVGPRQPGFDGREYIDALRFFAVILAKAGIQGFSCEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLM2</accession>
    <name>A0A0S2DLM2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DUF4398 domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BV903_04485</name>
        <name evidence="6" type="ORF">D9T17_07555</name>
        <name evidence="4" type="ORF">GLE_4254</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">C3</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">OH11</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000008">
        <property type="protein sequence ID" value="OPD65182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000020">
        <property type="protein sequence ID" value="ROU07630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4254"/>
    <dbReference type="EnsemblBacteria" id="ALN59595">
        <property type="protein sequence ID" value="ALN59595"/>
        <property type="gene ID" value="GLE_4254"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65182">
        <property type="protein sequence ID" value="OPD65182"/>
        <property type="gene ID" value="BV903_04485"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4254"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4194"/>
    <dbReference type="OMA" id="YGIACFI"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025511">
        <property type="entry name" value="DUF4398"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14346">
        <property type="entry name" value="DUF4398"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595229" evidence="2">
        <location>
            <begin position="26"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4398" evidence="3">
        <location>
            <begin position="33"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD65182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROU07630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <sequence length="125" mass="13004" checksum="3D1BF0C9D24599B9" modified="2016-02-17" version="1">MSASFAQIRLPLLAAVLASTLAGCASTPPPTGELSAAQQAVMRADDADADQYAPQDLNAARSALSAAQGALSQGKAEDARRLALRASAEADLAFARSKEALTNAELNQRRNEVAELRRRLQGGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLR4</accession>
    <name>A0A0S2DLR4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3919</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59261">
        <property type="protein sequence ID" value="ALN59261"/>
        <property type="gene ID" value="GLE_3919"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3919"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3856"/>
    <dbReference type="OrthoDB" id="1552399at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594940" evidence="2">
        <location>
            <begin position="23"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="224" mass="24382" checksum="1EFA37730B06A200" modified="2016-02-17" version="1">MARVGPRLAAWLLLSLGLVACARPAAPAAKDERPAPAAATVSPRPPDPPMAPPPVPEPGVRAEPEAVGSLPDGSATDAVRGLYDLHMQLRASGLPVGEDLARYRPYLSRHLLALMAPAARERDRMIAEQPGLKPPYLEGDMFTGLDEGATGYRVGARTALGPGRESVELEFVYDRSEPPVRWRGRALMLREDDRWKLDDVEYGDFDAGTTGEFVRSGRLADWFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM71</accession>
    <name>A0A0S2DM71_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">4-hydroxy-4-methyl-2-oxoglutarate aldolase</fullName>
            <shortName evidence="1">HMG aldolase</shortName>
            <ecNumber evidence="1">4.1.1.112</ecNumber>
            <ecNumber evidence="1">4.1.3.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Oxaloacetate decarboxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_20990</name>
        <name evidence="2" type="ORF">GLE_4287</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4-hydroxy-4-methyl-2-oxoglutarate = 2 pyruvate</text>
            <dbReference type="Rhea" id="RHEA:22748"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:58276"/>
            <dbReference type="EC" id="4.1.3.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + oxaloacetate = CO2 + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:15641"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="EC" id="4.1.1.112"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class II aldolase/RraA-like family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.112" evidence="1"/>
    <dbReference type="EC" id="4.1.3.17" evidence="1"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948935.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4287"/>
    <dbReference type="EnsemblBacteria" id="ALN59628">
        <property type="protein sequence ID" value="ALN59628"/>
        <property type="gene ID" value="GLE_4287"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4287"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4226"/>
    <dbReference type="OMA" id="YADWNGV"/>
    <dbReference type="OrthoDB" id="1614890at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047443">
        <property type="term" value="F:4-hydroxy-4-methyl-2-oxoglutarate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008948">
        <property type="term" value="F:oxaloacetate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008428">
        <property type="term" value="F:ribonuclease inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051252">
        <property type="term" value="P:regulation of RNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16841">
        <property type="entry name" value="RraA_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010203">
        <property type="entry name" value="RraA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005493">
        <property type="entry name" value="RraA/RraA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036704">
        <property type="entry name" value="RraA/RraA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03737">
        <property type="entry name" value="RraA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89562">
        <property type="entry name" value="SSF89562"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01935">
        <property type="entry name" value="NOT-MenG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="157" mass="16263" checksum="712652CED2A9DC57" modified="2016-02-17" version="1">MNTCDLCDRHDARVRVLDLPLRDFGGRIGFAGIVSTIKAYEDNSLVREAVAEPGVGRVLVIDGGGSSRRAMLGDQLAAQAVANGWAGVIVFGAIRDSAAIGAMALGVKALGTCPRKTDKHGQGLRDVALAFGGVAIRPGDWVCADEDGVVFADEALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMC6</accession>
    <name>A0A0S2DMC6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ABC_trans_aux domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4220"/>
    <dbReference type="EnsemblBacteria" id="ALN59561">
        <property type="protein sequence ID" value="ALN59561"/>
        <property type="gene ID" value="GLE_4220"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4220"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4162"/>
    <dbReference type="OMA" id="WSLRLNK"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005586">
        <property type="entry name" value="ABC_trans_aux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03886">
        <property type="entry name" value="ABC_trans_aux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC_trans_aux" evidence="1">
        <location>
            <begin position="63"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="239" mass="25572" checksum="6C538B04C93FF083" modified="2016-02-17" version="1">MNSATRRPDRRHANATTMPTTRALRPFSAAPLRLFGAGLAAALALSGCSILDEKPKTPTVQYAPDPRVPADPSWPQANWQLSVSVPSAARMIDSLRIAVRPSGDEVQVYKGAAWAKLPSNMIEDALLRTLEDSGKIAAVARQGSGIGAEYKLVLDLRRFESDYAGNAVPSAVIEINAKLFHTVDQKVVASRTFLQSTPAATTEVRDVVAAFERSLAAGTGEIAGWTLASGDAHEKSHKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMD3</accession>
    <name>A0A0S2DMD3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-acetylmuramoyl-L-alanine amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4371</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4371"/>
    <dbReference type="EnsemblBacteria" id="ALN59712">
        <property type="protein sequence ID" value="ALN59712"/>
        <property type="gene ID" value="GLE_4371"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4371"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4310"/>
    <dbReference type="OMA" id="DTRHPAQ"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06583">
        <property type="entry name" value="PGRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036505">
        <property type="entry name" value="Amidase/PGRP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002502">
        <property type="entry name" value="Amidase_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01510">
        <property type="entry name" value="Amidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00644">
        <property type="entry name" value="Ami_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55846">
        <property type="entry name" value="SSF55846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595380" evidence="1">
        <location>
            <begin position="37"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetylmuramoyl-L-alanine amidase" evidence="2">
        <location>
            <begin position="44"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="274" mass="30161" checksum="A65FC37009E3D17E" modified="2016-02-17" version="1">MFYTRVFATTRRMTSRSLSLSAVLCAALALAGCASAPPHNPLAQWRGSPNHNERRAQLIVLHHTQMDSAEQALRTLQTANSQGRVSAHYLVGEDGRIYQLVAEDRRAWHAGAGRWGEIGDLNSVSIGIELDNDGSEPFAEAQVQSLLRLLDDLTRRLGIDRQAILAHGDLAPSRKSDPSVLFPWKRLADAGFGLWPREPLAPPPPGFDPWAALRLIGYDLRDPGAALASFHRRFRGNEAREWQAGDAEVLYDLQRQLLALPDGAPPPLPAPPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DME3</accession>
    <name>A0A0S2DME3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4558</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4558"/>
    <dbReference type="EnsemblBacteria" id="ALN59899">
        <property type="protein sequence ID" value="ALN59899"/>
        <property type="gene ID" value="GLE_4558"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4558"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4494"/>
    <dbReference type="OMA" id="QVERIYG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595836" evidence="2">
        <location>
            <begin position="22"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="460" mass="49226" checksum="412FFCD68B747F50" modified="2016-02-17" version="1">MRLRPTALAVLTAALCFSAQARPPVAAPAASAAPPGAQDGIHAETGAQRGSVRAASARAASVFTLDDAFGRIQDTHPDLRLFGNQRSVLEAERDIAAQKPAYVAGASIDNALGTGALSGTKAAEVTLTLASVFERGGKLDARRAFAQSRIDALAVDREGRRLDLLAETARRYLAVVAEQRRIELAEFDIAQRKRAVAAARVRLEAGASPESGLLTAQAQLARAELDRSRAQRALLAARQFLAALWGERDPGFAAVAGDPFALPQVQDATALASLLERNPELTRFVDQRRIAESRVRLAQTQSKADVDWQVGLRRQQENGDFGFVASVSMPLGAAARAEPGIRGAQAELAMLETEREAKGLSLYSTLVEAQGRYRLGALETERLKQDVLPRLERAEKAAEYAYRAGAISYLELALLQAESVAVRRQRLDAALDAQLALIEIQRLTGEPFLAVTTAPAGATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DME7</accession>
    <name>A0A0S2DME7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 14">D-alanine--D-alanine ligase</fullName>
            <ecNumber evidence="6 14">6.3.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">D-Ala-D-Ala ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">D-alanylalanine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">ddlA</name>
        <name evidence="14" type="synonym">ddl</name>
        <name evidence="19" type="ORF">BV903_07580</name>
        <name evidence="21" type="ORF">D9T17_08090</name>
        <name evidence="20" type="ORF">FE772_20240</name>
        <name evidence="18" type="ORF">GLE_4129</name>
    </gene>
    <organism evidence="18 22">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="18 22" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 22">C3</strain>
        </source>
    </reference>
    <reference evidence="19 23" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 23">B25</strain>
        </source>
    </reference>
    <reference evidence="21 24" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 24">OH11</strain>
        </source>
    </reference>
    <reference evidence="20 25" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 25">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 14">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>ATP + 2 D-alanine = ADP + D-alanyl-D-alanine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11224"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="15">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="15">Binds 2 magnesium or manganese ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 14">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 14">Belongs to the D-alanine--D-alanine ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.4" evidence="6 14"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000015">
        <property type="protein sequence ID" value="OPD64517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000021">
        <property type="protein sequence ID" value="ROU07486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948809.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4129"/>
    <dbReference type="EnsemblBacteria" id="ALN59471">
        <property type="protein sequence ID" value="ALN59471"/>
        <property type="gene ID" value="GLE_4129"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64517">
        <property type="protein sequence ID" value="OPD64517"/>
        <property type="gene ID" value="BV903_07580"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4129"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4071"/>
    <dbReference type="OMA" id="MQGLLEC"/>
    <dbReference type="OrthoDB" id="764798at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008716">
        <property type="term" value="F:D-alanine-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00047">
        <property type="entry name" value="Dala_Dala_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000291">
        <property type="entry name" value="D-Ala_lig_Van_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005905">
        <property type="entry name" value="D_ala_D_ala"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011095">
        <property type="entry name" value="Dala_Dala_lig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07478">
        <property type="entry name" value="Dala_Dala_lig_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039102">
        <property type="entry name" value="Ddl/VanB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01205">
        <property type="entry name" value="D_ala_D_alaTIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00844">
        <property type="entry name" value="DALA_DALA_LIGASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 14" id="KW-0133">Cell shape</keyword>
    <keyword evidence="13 14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 14 18" id="KW-0436">Ligase</keyword>
    <keyword evidence="15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12 15" id="KW-0464">Manganese</keyword>
    <keyword evidence="15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 14" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="17">
        <location>
            <begin position="117"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR039102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ALN59471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="OPD64517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="QCW27623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ROU07486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="325" mass="34575" checksum="0BCEA1B1FD46A634" modified="2016-02-17" version="1">MSVKFAALRVTDPAVFGRVAVLMGGTSAEREVSLDSGRGVLDALRSRGVDAFAVDGIPALIERIRVGGVDRVFNILHGNKGGGEDGVLQGVLEALGVPYTGSDVLGSALAMDKIRTKQVWIGSGLPTPRFKRIAKGDDVHAAAREIGLPVIIKPSCEGSSVGVSRVLADADIDEAVALAARYPGEMLMEQMIVGDELTVAVLIDGEGYTALPSIRIVPKGEWYDYHAKYIAEDTQYLCPGLDGAAEDEIRRLAMQAFVAAGCKGWGRVDFMRDRDGRFYLIEVNTAPGMTSHSLVPKAARQVGIEYDELCWRVLEATVVAGGGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMF6</accession>
    <name>A0A0S2DMF6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lanthionine synthetase C-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4429</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4429"/>
    <dbReference type="EnsemblBacteria" id="ALN59770">
        <property type="protein sequence ID" value="ALN59770"/>
        <property type="gene ID" value="GLE_4429"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4429"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4366"/>
    <dbReference type="OMA" id="CENLIAC"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04792">
        <property type="entry name" value="LanM-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007822">
        <property type="entry name" value="LANC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025410">
        <property type="entry name" value="Lant_dehyd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017146">
        <property type="entry name" value="Lanti_2_LanM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13575">
        <property type="entry name" value="DUF4135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05147">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037228">
        <property type="entry name" value="Lant_mod_RumM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01950">
        <property type="entry name" value="LANCSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM01260">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03897">
        <property type="entry name" value="lanti_2_LanM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4135" evidence="2">
        <location>
            <begin position="106"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="519"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="942" mass="100931" checksum="82D04B4C4D5D476D" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DML3</accession>
    <name>A0A0S2DML3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc-dependent peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_21225</name>
        <name evidence="1" type="ORF">GLE_4340</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948976.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4340"/>
    <dbReference type="EnsemblBacteria" id="ALN59681">
        <property type="protein sequence ID" value="ALN59681"/>
        <property type="gene ID" value="GLE_4340"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4340"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4279"/>
    <dbReference type="OMA" id="EHSGEAW"/>
    <dbReference type="OrthoDB" id="1806453at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd20169">
        <property type="entry name" value="Peptidase_M90_mtfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010384">
        <property type="entry name" value="MtfA_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042252">
        <property type="entry name" value="MtfA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30164">
        <property type="entry name" value="PTHR30164"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06167">
        <property type="entry name" value="Peptidase_M90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="248" mass="27809" checksum="97CD47B0C92EEE05" modified="2016-02-17" version="1">MFEFLRRLRRPAAIDDALWRDTVAAVPWAQALDAPRRERLRELSARFLHEKTISAIGEFELGDLQRAQLAALCCLPLLEFGAEGLRGWSQLIVYPDAFRVGRTHLDAAGVLHEWEDELIGESWEAGPLILSWADVAADCADPRAGFCVAAHEMAHKLDALDGALDGTPPLPRPWQREWARHFQSAYDAFIEAVDSGCEVAIDPYAGEAPEEFFAVATEYHFSDPRLLREAMPEVADHLRRLYGESPFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMW4</accession>
    <name>A0A0S2DMW4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator HexR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">hexR</name>
        <name evidence="3" type="ORF">GLE_4618</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949186.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4618"/>
    <dbReference type="EnsemblBacteria" id="ALN59959">
        <property type="protein sequence ID" value="ALN59959"/>
        <property type="gene ID" value="GLE_4618"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4618"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4553"/>
    <dbReference type="OMA" id="VPFIHRS"/>
    <dbReference type="OrthoDB" id="992687at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05013">
        <property type="entry name" value="SIS_RpiR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000281">
        <property type="entry name" value="HTH_RpiR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035472">
        <property type="entry name" value="RpiR-like_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01418">
        <property type="entry name" value="HTH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51071">
        <property type="entry name" value="HTH_RPIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH rpiR-type" evidence="1">
        <location>
            <begin position="3"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="2">
        <location>
            <begin position="123"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="290" mass="29749" checksum="62AEE9A86F486CBB" modified="2016-02-17" version="1">MSDNLIPAIRGALHALRPAERKVAAVVLAELDFAAGASIRELAARAGVSEPSVTRFSRAVGCGSLRQFKRRLSHSLAAGVPYQAVTIDKRDGAALLVHKVCDSIAAALDEMRERTDPAALDEAAALIAGARRVCCIGVGPGCAAVAQEACLRLQRLDIAASAHSDGESQRLAAGLLGAQDALLAISLSGCSAEIADCARIARRQGARTIALTAAGTPLSRDADVPLLLPPSSAATPYSPGVAQLMQLALADMLAIAVALRQQPAVLEKARRAAVGLERAPSAPAPGTVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN03</accession>
    <name>A0A0S2DN03_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase, families S8 and S53/outer membrane autotransporter barrel domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_4579</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949159.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4579"/>
    <dbReference type="EnsemblBacteria" id="ALN59920">
        <property type="protein sequence ID" value="ALN59920"/>
        <property type="gene ID" value="GLE_4579"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4579"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4516"/>
    <dbReference type="OMA" id="GMHGVAY"/>
    <dbReference type="OrthoDB" id="1713183at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04848">
        <property type="entry name" value="Peptidases_S8_Autotransporter_serine_protease_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005546">
        <property type="entry name" value="Autotransporte_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036709">
        <property type="entry name" value="Autotransporte_beta_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006315">
        <property type="entry name" value="OM_autotransptr_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034061">
        <property type="entry name" value="Peptidases_S8_Autotransporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03797">
        <property type="entry name" value="Autotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00869">
        <property type="entry name" value="Autotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103515">
        <property type="entry name" value="SSF103515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01414">
        <property type="entry name" value="autotrans_barl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51208">
        <property type="entry name" value="AUTOTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
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        <location>
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            <end position="1045"/>
        </location>
    </feature>
    <feature type="domain" description="Autotransporter" evidence="5">
        <location>
            <begin position="767"/>
            <end position="1045"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1045" mass="109451" checksum="52426478090F30B4" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNF5</accession>
    <name>A0A0S2DNF5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Gfo/Idh/MocA family oxidoreductase</fullName>
        </submittedName>
        <submittedName>
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        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">GLE_4614</name>
    </gene>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_4614"/>
    <dbReference type="EnsemblBacteria" id="ALN59955">
        <property type="protein sequence ID" value="ALN59955"/>
        <property type="gene ID" value="GLE_4614"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4614"/>
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    <dbReference type="OMA" id="MESGKHA"/>
    <dbReference type="OrthoDB" id="1465613at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
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    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
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    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51735"/>
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    </dbReference>
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        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="34"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="454" mass="49803" checksum="A2E092F746C72CE1" modified="2016-02-17" version="1">MNRRDFIASSATAGTLLAANAFAPALARKRSTLRLGMIGTGMRGQVLLKELVRRDDVEVVALCDIEPIMLGRALAMIDKAGKPKPATYGDGGDGGDVEAYRKMLAKGGLDGVIVATPWEYHAPMAIAAMQAGIAVGCEVVAGITLDDHWQVLRTQLKTGTPYMLLENVCYRRDVLAVLNMVRQGLFGELVHLQGGYQHDLRAVKFNNGNPDQPYGSGVEFGPKGWSEARWRTEHSVKRDGDLYPSHGIGPCAMAANIHRGNRFTYLSAMSSKPRGLHDYIVKKAGADHPNAKVKFKLGDLVTTQIACANGETIVLQHDTSLPRPYSLGFRVQGTDGLWMDVNDSIHIEGKSKPHEWDKAEVWLDKYDHPLWKRHGATAAGAGHGGMDWFVINAFVEALKAGAPMPIDIFDAVAWSAITPLSEQSIAEHRTLEFPDFTDGKWKDRKPIFGFDELY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNU1</accession>
    <name>A0A0S2DNU1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thioredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">trx</name>
        <name evidence="9" type="synonym">trxA</name>
        <name evidence="8" type="ORF">BV903_06745</name>
        <name evidence="10" type="ORF">D9T17_04925</name>
        <name evidence="9" type="ORF">FE772_23865</name>
        <name evidence="7" type="ORF">GLE_4917</name>
    </gene>
    <organism evidence="7 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 11">C3</strain>
        </source>
    </reference>
    <reference evidence="8 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">OH11</strain>
        </source>
    </reference>
    <reference evidence="9 14" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 14">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the thioredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000012">
        <property type="protein sequence ID" value="OPD64725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000014">
        <property type="protein sequence ID" value="ROU08258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949414.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000014.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4917"/>
    <dbReference type="EnsemblBacteria" id="ALN60258">
        <property type="protein sequence ID" value="ALN60258"/>
        <property type="gene ID" value="GLE_4917"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64725">
        <property type="protein sequence ID" value="OPD64725"/>
        <property type="gene ID" value="BV903_06745"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4917"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4847"/>
    <dbReference type="OMA" id="CRVISPI"/>
    <dbReference type="OrthoDB" id="1630944at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 5" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="6">
        <location>
            <begin position="4"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="5">
        <location>
            <begin position="33"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN60258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD64725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW28232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROU08258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="110" mass="12057" checksum="5EA99BF6964D3D75" modified="2016-02-17" version="1">MSEKVLHAGAADFDATVLQSSEPVLVDFWAPWCGPCKAIGPIVEQLADQYDGRAKVVKVDVQEHPALGVRFNIRSIPMLMMFKDGQIHSTQLGAPPNIKTLLTQMIDKAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNW2</accession>
    <name>A0A0S2DNW2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UDP-glucoronosyl and UDP-glucosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4895"/>
    <dbReference type="EnsemblBacteria" id="ALN60236">
        <property type="protein sequence ID" value="ALN60236"/>
        <property type="gene ID" value="GLE_4895"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4895"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4826"/>
    <dbReference type="OMA" id="ICPFFGD"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030259">
        <property type="term" value="P:lipid glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033072">
        <property type="term" value="P:vancomycin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_28" evidence="1">
        <location>
            <begin position="26"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="461" mass="49640" checksum="1A1E7133028AACA9" modified="2016-02-17" version="1">MSASASAVAATLPIAAQPTDPTPGAVVIFTVGTQGDARPCIGLGQSLKRAGYPVRIVTSENFAPLVREAGLEFAAISADFSDLLTNNPETVDKALNPWYLVQHTRAKFAQWAATWAQEARPACKGAALLVGTGIVTQLAKAIGEADGIPFIQAHLQPFTPSRKLSPLSFWSEREFPGAVNMALFSVMKLLAWYTLKPAVNGAIRPQLKLPLFPWYGPFFDKNPERMRVLYGYSRHILPPPDDWPAEVKVTGSWFLDQADVWQPPQALADFLAEGDKPVYFGFGSMLANNAEALTQVVLDAVRLSGRRAVLATGWGGLRCDPGRLNDQVYVIEAAPHDWLFPRMAATVQHGGAGTTVAAARAGVPSVFVPFFGDQPFWARRMHALGAAPPALDRRTVTAEQMAQAVAQALQPERVRAAAELGEKIRAENGGASAVRALTEWGLLPPPRLARDTAAPALERVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP10</accession>
    <name>A0A0S2DP10_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SpoIID/LytB domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4706</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949250.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4706"/>
    <dbReference type="EnsemblBacteria" id="ALN60047">
        <property type="protein sequence ID" value="ALN60047"/>
        <property type="gene ID" value="GLE_4706"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4706"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4640"/>
    <dbReference type="OrthoDB" id="1584918at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030435">
        <property type="term" value="P:sporulation resulting in formation of a cellular spore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013486">
        <property type="entry name" value="SpoIID/LytB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013693">
        <property type="entry name" value="SpoIID/LytB_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30032:SF4">
        <property type="entry name" value="PTHR30032:SF4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08486">
        <property type="entry name" value="SpoIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoIID" evidence="1">
        <location>
            <begin position="339"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="713" mass="74779" checksum="FF4B2F401B94CB55" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP37</accession>
    <name>A0A0S2DP37_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase</fullName>
            <ecNumber evidence="1">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4816</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949333.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4816"/>
    <dbReference type="EnsemblBacteria" id="ALN60157">
        <property type="protein sequence ID" value="ALN60157"/>
        <property type="gene ID" value="GLE_4816"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4816"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4747"/>
    <dbReference type="OMA" id="DFQARGC"/>
    <dbReference type="OrthoDB" id="417859at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901605">
        <property type="term" value="P:alpha-amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="42"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="414" mass="44821" checksum="6333176DB4FA68D8" modified="2016-02-17" version="1">MNPMTDPAPAQSAPRDAFALLKTLAERHRARQDAPGFAGAPLLDLSIGNPDLAPEPRWRERLQHYVGRDDLHGYGEFRADLNQRLRERFAAYYQRRFLPAGAPTLLDPQRHVVDLLGSKEGIFHSLFACLKPGDAVLMPDPSYTVYQSTARLLGARVELFACDERGQPRLESIRAEQLRGARVLVICSPSNPTGIALSPAKLDEVLDFARRHDLYVLIDRAYAEIAFEPPRGGVLGGAALPAPGALERVLELHSLSKSCGLAGWRIGFAAGAPALVAKIRAAKFNADFGTFLPLQCVAAEMLDELETIAARNSAVYAARMRRFVDGAAALGWRIAPSHGTFFLWAPLPPGFDGDDLDFVEALLDATGVLVAPGSGFGPGGAGRVRIALVQAEAVLDEALRRLRAWPALRRDAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP52</accession>
    <name>A0A0S2DP52_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_23480</name>
        <name evidence="1" type="ORF">GLE_4832</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949347.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4832"/>
    <dbReference type="EnsemblBacteria" id="ALN60173">
        <property type="protein sequence ID" value="ALN60173"/>
        <property type="gene ID" value="GLE_4832"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4832"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4763"/>
    <dbReference type="OMA" id="WAWKIAQ"/>
    <dbReference type="OrthoDB" id="1688794at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="167" mass="18299" checksum="753D4354EA003AF6" modified="2016-02-17" version="1">MVFDYMDYFVSMSVGLTGFASEAIAPEIDPVGIKAVYLQAFDEKLPDGMAEQILQRYKALFDAAGGKPGNEEQLVGQMLAGSGTSPAQILAMRQLIFLWYAGAWPTVQYDNSPSRGQTFSSVISAESYTQGLVWRVMQSHPMGSSTYNYGYWAADPPPLSAYLENPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP87</accession>
    <name>A0A0S2DP87_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4864</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4864"/>
    <dbReference type="EnsemblBacteria" id="ALN60205">
        <property type="protein sequence ID" value="ALN60205"/>
        <property type="gene ID" value="GLE_4864"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4864"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4796"/>
    <dbReference type="OMA" id="ADFYAWY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="302" mass="31423" checksum="0D297A807ABC0718" modified="2016-02-17" version="1">MLAELQAGDAAAGDAALVAAMAGFRSLAAETALNEWPARFWSLLLTQPGLRQRTAVAIALDATDRLGELGSGPRAALLLRLAAGLAEPEAAAVLHVAPATYRMALQRALPRHADGSADPQAWQQLREQIHRRIKTLPPERLQRLAQARDAALRNAAPGAAPPGRRAPVQARPRPRWLMPLLWSLLALCALAFAATFWWPAGLPGGWLGDGPDGVTVAPLAEGSGPAERYSRDAGLIADGDFGLLADPQGEAASAAVDFDSWLAARDAGTIPAVAAPPAEPAATPDPAGSDRAGLETDAQEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPB9</accession>
    <name>A0A0S2DPB9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Patatin-like phospholipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_4896</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949399.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60237">
        <property type="protein sequence ID" value="ALN60237"/>
        <property type="gene ID" value="GLE_4896"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4896"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4827"/>
    <dbReference type="OMA" id="LINWGYA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN60237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="421" mass="47847" checksum="891D23C18FE822A4" modified="2016-02-17" version="1">MQSTDVELERLRVRREARRAELAAHSGVNQREGRALCLSGGGYRAALFHLGGLLRLHEAGLLAGLSLVSSVSGGSIVSAWLACRYLDTRRDRDESFAAWSDRIDFRAEVVEPFRAVAARDIRTLPVLATLPFNWLKPSWRIGLLERGYIRAFGERHLDELPECPSFVFCATDLSFGVNWEFSRRRVGDYLAGYLRDGARRVRLSCAVAASSCFPPVFGPVRFEAAPGDYQRGDYRGDDGDALRARIELSDGGVYDNLATEPSLRRYREVLVSDAGGPFVFESKRWWLSRLMRYTQVIGNQAEALRKRLFFGQAESGSFSGVYWSLTGYRDEGADGYSPALVREVLGRLRTDLDRFLDVEFEVLVNHGYFAAHDALWRQNGWVSETSPAVWPYPDRADENRVRRWLRRSHARVLHRRWWGAS</sequence>
</entry>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    </dbReference>
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    </dbReference>
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            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60486.1"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="QCW28413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="189" mass="19397" checksum="049E43AEE70326D3" modified="2016-02-17" version="1">MSDPHAPHADASGLEQELLEDQALSAAERYAAFLAAVADSGRFWVAESGEYLLTLFDGDGQELLPAWPSAATARAALAQARAQSPNLAGYAPAPRELAAWRERAAAAMDEAGVGVGAFPDLAMQCAVVAPAQLLEHLDALIAESDADAATEADETDGDAGDDSAGAPAALDLAQAQRALAQKFAKPKGD</sequence>
</entry>
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        <source>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <property type="gene ID" value="GLE_5124"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5124"/>
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="105" mass="10736" checksum="7D8868C69E3CFFCE" modified="2016-02-17" version="1">MSSIGPDSRIDRAGLDSQTLEALRVREPATQGASLPAAVAEAVPAYAPPARDPGEETLNADAWRGVAAGERQLPGDSGLERELGQLDLSAAADRGADAVLDSLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPR8</accession>
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    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 4">C3</strain>
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    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
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                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="gene ID" value="GLE_5094"/>
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        <property type="gene ID" value="BV903_16700"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD62811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="74" mass="8660" checksum="423A264AD9AE80EC" modified="2016-02-17" version="1">MHRTRAELDGDLCQLTAALPLWRRHWSDDAVFWPRVDSLIERLLTVTPRDDRCRVVSHINRIIAAQGLEHAPYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPV6</accession>
    <name>A0A0S2DPV6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5155</name>
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    <organism evidence="2 3">
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="gene ID" value="GLE_5155"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5155"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5078"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="54" mass="5912" checksum="91B7C2D271E745B3" modified="2016-02-17" version="1">MGRRRIHCVHDTEAPPQRPASFGGTPRPAKPGAAALKFRPDRHAAFETPAPPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQH3</accession>
    <name>A0A0S2DQH3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">LacI family DNA-binding transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">LacI family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, lacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BV903_11205</name>
        <name evidence="8" type="ORF">D9T17_04005</name>
        <name evidence="7" type="ORF">FE772_24875</name>
        <name evidence="5" type="ORF">GLE_5131</name>
    </gene>
    <organism evidence="5 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 9">C3</strain>
        </source>
    </reference>
    <reference evidence="6 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">OH11</strain>
        </source>
    </reference>
    <reference evidence="7 12" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 12">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000026">
        <property type="protein sequence ID" value="OPD63866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000012">
        <property type="protein sequence ID" value="ROU08460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949578.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000012.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5131"/>
    <dbReference type="EnsemblBacteria" id="ALN60472">
        <property type="protein sequence ID" value="ALN60472"/>
        <property type="gene ID" value="GLE_5131"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63866">
        <property type="protein sequence ID" value="OPD63866"/>
        <property type="gene ID" value="BV903_11205"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5131"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5056"/>
    <dbReference type="OMA" id="SHYQAMI"/>
    <dbReference type="OrthoDB" id="664909at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00036">
        <property type="entry name" value="HTHLACI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD63866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW28404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROU08460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="341" mass="37638" checksum="632E3F0A8EB5AAD8" modified="2016-02-17" version="1">MRVRIEDVAEEAGVSMKTVSRVLNQEPNVSEETRKRVEAAARKLQYRPNPSARSLAGQRSFLVALLYDNPSSNYLMEVQAGMLDACNSQHYNLMLAPVTYTDKKLVAHVDEIVQRSRADGLVLTPPLTDHPGLMKRLGQLAIPYANISPKLRGERIGVVLDEERAVRELMAHLVSLGHRRIAHIKGHPEHGASQWRLNGYRDGLAAAGIGFDPELVVEGDFHYDTGAICAQRLLLMDDPPTAIFAANDDMAAGTIRTASEMGLSIPGDVSVCGFDDTPISRQIYPPLTTVRQPTREMGRLATHELFKRIKAPDAGQLILAPYELQLRKSTGPVGKPRARKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQL1</accession>
    <name>A0A0S2DQL1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="2">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hsdM</name>
        <name evidence="6" type="ORF">GLE_5543</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5543"/>
    <dbReference type="EnsemblBacteria" id="ALN60884">
        <property type="protein sequence ID" value="ALN60884"/>
        <property type="gene ID" value="GLE_5543"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5543"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5464"/>
    <dbReference type="OMA" id="TRHFYKY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="D12N6_MeTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HsdM_N" evidence="5">
        <location>
            <begin position="66"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="N6_Mtase" evidence="4">
        <location>
            <begin position="210"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="27"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN60884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="727" mass="81913" checksum="A071A5E2BA1812C0" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQU2</accession>
    <name>A0A0S2DQU2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_00885</name>
        <name evidence="1" type="ORF">GLE_5533</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949871.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60874">
        <property type="protein sequence ID" value="ALN60874"/>
        <property type="gene ID" value="GLE_5533"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5533"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5452"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="74" mass="8177" checksum="CD9B31827409AC48" modified="2016-02-17" version="1">MTQPTDPLDSLSVSPAAQVIDYVPASAASPPADDMDSMSPYEKLAYLAYVLPARIYAANPWLLDPKYRNYLENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQZ3</accession>
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        </submittedName>
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        <name evidence="3" type="ORF">GLE_5394</name>
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    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW24328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_5394"/>
    <dbReference type="EnsemblBacteria" id="ALN60735">
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        <property type="gene ID" value="GLE_5394"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5394"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5309"/>
    <dbReference type="OMA" id="MIKTTPL"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
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        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242244" evidence="2">
        <location>
            <begin position="23"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="170" mass="17460" checksum="CDBA31D5DC100852" modified="2016-02-17" version="1">MLIRNRTTYAVAAALVASLALAGCKKKEEPAPTPPPAAETPAPAPAPEPAPAPVAATATVASVDLGSAVGADKKVTAAATTFKPKDTVHASVTTNTSDPSATVATKIGAKWTFQDGQTVKEDQPTEINATNGGVTEFSINSPKGFPEGKYKVEITQDGNVVQSKEFEVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DR67</accession>
    <name>A0A0S2DR67_LYSEN</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
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    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5474"/>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="102" mass="10458" checksum="3B8261F90AA270C2" modified="2016-02-17" version="1">MRAQFVSLARGSAQAIDARYARMSAATMAHEGSAIPLTGCACFYGNARYSARRGSMRGESPSALRASRARCGCLLGSYTPSRGGGEAAAAADDVWCGASVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA34</accession>
    <name>A0A0S2DA34_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_01145</name>
        <name evidence="1" type="ORF">GLE_0043</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55402">
        <property type="protein sequence ID" value="ALN55402"/>
        <property type="gene ID" value="GLE_0043"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0043"/>
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    <dbReference type="OrthoDB" id="2210869at2"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="109" mass="12137" checksum="B8AB8DF4FC68BB39" modified="2016-02-17" version="1">MVTPPGAVYDVVNHGSLGWRIRLNDEDEPRYFPNREGCVAEAAARARHQHALTGQPTEVWAPGYDGVRQCVVRYMKPSDLDELLRRGTSHFQLLGVSYADGPLFLNAQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA97</accession>
    <name>A0A0S2DA97_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    <organism evidence="1 2">
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        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="ALN55447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="277" mass="31472" checksum="94CCE6948DE071D3" modified="2016-02-17" version="1">MTEPDRLHEIHPIAEDKRRAVLDALAAIEREHDVRVIYACESGSRGWGFSSPDSDYDARFVYVHRQPWYLTVNERTGPGEPQRDVIELPIEADLDVAGWDLRKALRLVSKSNPTLLEWLRSPIVYRRDDALAAGLHGLAERFYSPVAAWHHYLSLARGTFNAHLGGDSIRTKKYLYVLRPVLACQWIEREDVAPPMAFESLLERLLPDGPVREAIEDLLVRKRRSAEVEAGPRVPALSDFLAAELERMQTQPPQLAPGRGRGEELDEFLRAALAQPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA98</accession>
    <name>A0A0S2DA98_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">GLE_0053</name>
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    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ALN55412">
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        <property type="gene ID" value="GLE_0053"/>
    </dbReference>
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    <dbReference type="PATRIC" id="fig|69.6.peg.60"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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        <property type="project" value="InterPro"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="68" mass="7725" checksum="FEF0FC94E3984834" modified="2016-02-17" version="1">MRKERGYSQDHLAYSIPIDRAHVGLIENGKSAASIITLVKFAIALECEVGDLFPYVEDLRPYADWLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAE3</accession>
    <name>A0A0S2DAE3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_01690</name>
        <name evidence="2" type="ORF">GLE_0161</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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            <taxon>Proteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945838.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55520">
        <property type="protein sequence ID" value="ALN55520"/>
        <property type="gene ID" value="GLE_0161"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0161"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.163"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="163" mass="17850" checksum="3847886C234521C5" modified="2016-02-17" version="1">MPPTPSKPRRFTVGTPWLFGFGAFACAGAVVLAAIAAYQRVWIGVAVTTMLFGGSGAALMLTAVTLEGDEDGLTVIRLHKRVRIAWRDIVAAAGDARSLSLRTRELRETVLSYSHWRGADKNRLYLLMREKLLAHGAQVEPGLRGFLRMDEDLSGVLPREGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAN0</accession>
    <name>A0A0S2DAN0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase, 2-nitropropane dioxygenase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945887.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0230"/>
    <dbReference type="EnsemblBacteria" id="ALN55589">
        <property type="protein sequence ID" value="ALN55589"/>
        <property type="gene ID" value="GLE_0230"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0230"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.232"/>
    <dbReference type="OMA" id="MDNARPF"/>
    <dbReference type="OrthoDB" id="275153at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NMO" evidence="1">
        <location>
            <begin position="7"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="356" mass="37234" checksum="D56B9379FA4D4C4B" modified="2016-02-17" version="1">MWPDRRIQELFGIALPIVQAPMAGAHDAALAIAAARAGALGSLPCAMLSPQQAREQVAQYRAATDAPVNLNFFCHRPAAADPAREAAWRERLRPYYLEFGLDPAAASAAAARAPFDEAWCALVEELRPQVVSFHFGLPAPELLARVRASGARAIASATTVAEAVWLEQRGCDAIVAQGNEAGGHRGVFLEGEDVSTQAGLFALLPRIADAVTVPVIAAGGVFDGRGIAAAFALGAAAVQVGTAYLFCPEATIAPLHRRALSAGEGDDTALTNVFSGRPARGIVNRAMRELGPLSPLAPAFPGAGAALAPLRARAEPAGDDDFMSLWSGQARRAHALGAFELTRELARQAQDLLDRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAQ5</accession>
    <name>A0A0S2DAQ5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA/pantothenate metabolism flavoprotein</fullName>
            <ecNumber evidence="2">4.1.1.36</ecNumber>
            <ecNumber evidence="2">6.3.2.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.1.1.36" evidence="2"/>
    <dbReference type="EC" id="6.3.2.5" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0251"/>
    <dbReference type="EnsemblBacteria" id="ALN55610">
        <property type="protein sequence ID" value="ALN55610"/>
        <property type="gene ID" value="GLE_0251"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0251"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.253"/>
    <dbReference type="OMA" id="NTRMYDH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004632">
        <property type="term" value="F:phosphopantothenate--cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004633">
        <property type="term" value="F:phosphopantothenoylcysteine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015941">
        <property type="term" value="P:pantothenate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005252">
        <property type="entry name" value="CoaBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="SSF52507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00521">
        <property type="entry name" value="coaBC_dfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavoprotein" evidence="1">
        <location>
            <begin position="13"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="194" mass="20556" checksum="C6AF2D1A6F8EAC6E" modified="2016-02-17" version="1">MAQDPTPPLHAQRILLCVCGGIAAYKAADLVRRLQDAGAQVRVAMTENATRFVGPATFQALSGQPVRTSLWDEAAELAMGHIELARWAQRILIAPATADMIAKLAHGFADDLISTLCLASEAPVTIAPAMNHRMWGHPATQANVATLRERGVGFLGPGEGRMAEPESGPGRLLEPHEIVSALEQAAALAQEARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAR8</accession>
    <name>A0A0S2DAR8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Ribokinase</fullName>
            <shortName evidence="6">RK</shortName>
            <ecNumber evidence="2 6">2.7.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">rbsK</name>
        <name evidence="8" type="ORF">GLE_0192</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + D-ribose = ADP + D-ribose 5-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13697"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:47013"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="6">Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Carbohydrate metabolism; D-ribose degradation; D-ribose 5-phosphate from beta-D-ribopyranose: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.15" evidence="2 6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0192"/>
    <dbReference type="EnsemblBacteria" id="ALN55551">
        <property type="protein sequence ID" value="ALN55551"/>
        <property type="gene ID" value="GLE_0192"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0192"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.194"/>
    <dbReference type="OMA" id="AMDSIPF"/>
    <dbReference type="UniPathway" id="UPA00916">
        <property type="reaction ID" value="UER00889"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004747">
        <property type="term" value="F:ribokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019303">
        <property type="term" value="P:D-ribose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01174">
        <property type="entry name" value="ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01987">
        <property type="entry name" value="Ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011877">
        <property type="entry name" value="D_ribokin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002139">
        <property type="entry name" value="Ribo/fructo_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00990">
        <property type="entry name" value="RIBOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 6" id="KW-0630">Potassium</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="7">
        <location>
            <begin position="8"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="16"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="44"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="213"/>
            <end position="218"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="244"/>
            <end position="245"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN55551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="319" mass="32138" checksum="84A5A03596D20035" modified="2016-02-17" version="1">MTANTPRTVLVAGSANLDFVVRAAHAPAPGETVLGRELATYPGGKGANQALACAHAGAAPTRMLLALGEDAHAEPIERSLREGGVELHVRRCAERATGSAFVCVADDGENAIVVAPGANAALRGDDLPALDGIAWLLLQLESPLDAVADWARQARAAGVAVALNAAPARALPAALLDDVDLLIVNEGELAALTGIDDLDAAVAAVRVPRVVVTLGARGCLARVDGARLRQDAFAVEAVDTTAAGDTFCGVLVAALARGDGFDTALRRACAASALACTRPGAQSSVPSHAEVEALLHTAADRNSAGGTSVPMPSAQVAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAZ0</accession>
    <name>A0A0S2DAZ0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">LacI family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BV903_18885</name>
        <name evidence="7" type="ORF">FE772_02515</name>
        <name evidence="5" type="ORF">GLE_0343</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000053">
        <property type="protein sequence ID" value="OPD62359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945967.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000053.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0343"/>
    <dbReference type="EnsemblBacteria" id="ALN55701">
        <property type="protein sequence ID" value="ALN55701"/>
        <property type="gene ID" value="GLE_0343"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62359">
        <property type="protein sequence ID" value="OPD62359"/>
        <property type="gene ID" value="BV903_18885"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0343"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.340"/>
    <dbReference type="OMA" id="DGLIFCS"/>
    <dbReference type="OrthoDB" id="1796334at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="7"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN55701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD62359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW24713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="342" mass="37048" checksum="0E6ACA1FCDCD42B2" modified="2016-02-17" version="1">MRKKTKATSVDIAHLAGVSQATVSRVLSGSPLVNAETRKRVEAVVRELNYKVDRHASSLRRQRSGTLALLLFEDPTPDESHINPFFLSMLGSITRACARHGQDLLISFQQLSDDWAADYEDSMKADGLILLGYGDYLAYQGKLQRLVEQGTRFVRWGAVLPDQPGLSIGCENLGGGRQAGAHLVALGRRRVAFLGDASSHYPEFLDRFLGCEQALNDAGLALDRALQVDAESAEDAGHAAALELLARGLPFDAVFAASDLIAIGAMRALTERGLRVPEDVSVIGFDDLPMARFAHPPLTTVFQDTKQAGELLVEALMRLIRGEDAASQRLPTTLVVRKSCGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB33</accession>
    <name>A0A0S2DB33_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Carbohydrate kinase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Fructokinase-1</fullName>
            <ecNumber evidence="4">2.7.1.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">scrK</name>
        <name evidence="5" type="ORF">FE772_02665</name>
        <name evidence="4" type="ORF">GLE_0375</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.4" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945988.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0375"/>
    <dbReference type="EnsemblBacteria" id="ALN55733">
        <property type="protein sequence ID" value="ALN55733"/>
        <property type="gene ID" value="GLE_0375"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0375"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.372"/>
    <dbReference type="OMA" id="NWRPTFW"/>
    <dbReference type="OrthoDB" id="1604782at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008865">
        <property type="term" value="F:fructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="3">
        <location>
            <begin position="16"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN55733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW24736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="343" mass="36066" checksum="A4FDC966B589BCBA" modified="2016-02-17" version="1">MSAVPSSSGASGANAAIVCFGEALIDFLARPAQSPGEPRHFVEYAGGAPANVAVAAARLGAHARFVGMLGRDMFGDFIADQLSGYGVDTRDVRRTDAAKTALAFVSLDGDGERSFSFYRPPAADLLFRDADFSPDGFADAGVFHVCSNSLTEEAIAAATLAGMRRARLAGALVSMDMNLRPSLWPAGFDPAPRLLAALLEADLIKLCGSEFEFLARHLGGEEAALQRLWHGYATCVLITDGATPIRWYTRTRGGSVATFKVAPSDTTGAGDAFVGGLLRRLVALGVSAANFNDFLQREDELTDALRYAAAAGALATTRHGAFAAMPSAADVERLMQEQAQEPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB51</accession>
    <name>A0A0S2DB51_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Multifunctional CCA protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="11">CCA-adding enzyme</fullName>
                <ecNumber evidence="11">2.7.7.72</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="11">CCA tRNA nucleotidyltransferase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="11">tRNA CCA-pyrophosphorylase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="11">tRNA adenylyl-/cytidylyl-transferase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="11">tRNA nucleotidyltransferase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="11">tRNA-NT</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="11">2'-nucleotidase</fullName>
                <ecNumber evidence="11">3.1.3.-</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="11">2',3'-cyclic phosphodiesterase</fullName>
                <ecNumber evidence="11">3.1.4.-</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="11">Phosphatase</fullName>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="11 13" type="primary">cca</name>
        <name evidence="14" type="ORF">FE772_02425</name>
        <name evidence="13" type="ORF">GLE_0323</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">C3</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a tRNA precursor + ATP + 2 CTP = a tRNA with a 3' CCA end + 3 diphosphate</text>
            <dbReference type="Rhea" id="RHEA:14433"/>
            <dbReference type="Rhea" id="RHEA-COMP:10465"/>
            <dbReference type="Rhea" id="RHEA-COMP:10468"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:74896"/>
            <dbReference type="ChEBI" id="CHEBI:83071"/>
            <dbReference type="EC" id="2.7.7.72"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Magnesium is required for nucleotidyltransferase activity.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
        <text evidence="11">Nickel for phosphatase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Monomer. Can also form homodimers and oligomers.</text>
    </comment>
    <comment type="domain">
        <text evidence="11">Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="11">A single active site specifically recognizes both ATP and CTP and is responsible for their addition.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.72" evidence="11"/>
    <dbReference type="EC" id="3.1.3.-" evidence="11"/>
    <dbReference type="EC" id="3.1.4.-" evidence="11"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945952.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0323"/>
    <dbReference type="EnsemblBacteria" id="ALN55681">
        <property type="protein sequence ID" value="ALN55681"/>
        <property type="gene ID" value="GLE_0323"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0323"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.320"/>
    <dbReference type="OMA" id="RFECEGW"/>
    <dbReference type="OrthoDB" id="2018439at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052929">
        <property type="term" value="F:ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052928">
        <property type="term" value="F:CTP:3'-cytidine-tRNA cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052927">
        <property type="term" value="F:CTP:tRNA cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004112">
        <property type="term" value="F:cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016437">
        <property type="term" value="F:tRNA cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042245">
        <property type="term" value="P:RNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001680">
        <property type="term" value="P:tRNA 3'-terminal CCA addition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05398">
        <property type="entry name" value="NT_ClassII-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01261">
        <property type="entry name" value="CCA_bact_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012006">
        <property type="entry name" value="CCA_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032828">
        <property type="entry name" value="PolyA_RNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12627">
        <property type="entry name" value="PolyA_pol_RNAbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000813">
        <property type="entry name" value="CCA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="1 11" id="KW-0533">Nickel</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 11 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0692">RNA repair</keyword>
    <keyword evidence="10 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 11 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 11" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="HD" evidence="12">
        <location>
            <begin position="229"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="8"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022800"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN55681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW24697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="415" mass="45463" checksum="B48731B454242AA9" modified="2016-02-17" version="1">MKTYLVGGAVRDSLLGLPAGDRDYVVVGETPEAMLAAGFKAVGKDFPVFLHPDTGEEYALARTERKSGRGYRGFVVDADPSVSLEDDLGRRDFTINAIARDEGDGRLVDPYGGARDLEAKVLRHVGEAFVEDPLRVLRAARFMARFAAHGFSVAPETMALMRRMAESGELADLVPERVWQETRRALACATPSAFLRTLHEAGALAVALPEVDALYGVPQRPEYHPEVDTGIHTEMVVDMAARLAPGDDLIGFAALTHDLGKARTPADLLPRHHNHEHNGLQPLAELCARLKVPTDHRLLAEAVCREHLNVHRLAEMRPRSVYELIARCDGWRNPRRIEQMALVCEADKRGRLGLEDSDYPSRQALVDALHAGLKVRAGDLKPGLSGPAVGEAMRRARIEAIAALRREGTQDSPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB80</accession>
    <name>A0A0S2DB80_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0439</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55797">
        <property type="protein sequence ID" value="ALN55797"/>
        <property type="gene ID" value="GLE_0439"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0439"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="46" mass="5153" checksum="AE234B1ED2A63172" modified="2016-02-17" version="1">MSSSELKQERSPLFRANMKTGMSDMPAIKQQHGRTASRANPRPLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBC9</accession>
    <name>A0A0S2DBC9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0472</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55830">
        <property type="protein sequence ID" value="ALN55830"/>
        <property type="gene ID" value="GLE_0472"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0472"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.468"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="39" mass="4063" checksum="C5541137E3B7E169" modified="2016-02-17" version="1">MQHMTVHDPVQSDAVQPSTLSNTRSACANSPLENNGPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBP5</accession>
    <name>A0A0S2DBP5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Siderophore-interacting FAD-binding domain protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Siderophore-interacting protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_03080</name>
        <name evidence="2" type="ORF">GLE_0463</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946055.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0463"/>
    <dbReference type="EnsemblBacteria" id="ALN55821">
        <property type="protein sequence ID" value="ALN55821"/>
        <property type="gene ID" value="GLE_0463"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0463"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.459"/>
    <dbReference type="OMA" id="VHAFVHG"/>
    <dbReference type="OrthoDB" id="1630289at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FAD-bd_9_SIP"/>
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        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
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        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007037">
        <property type="entry name" value="SIP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039374">
        <property type="entry name" value="SIP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30157">
        <property type="entry name" value="PTHR30157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08021">
        <property type="entry name" value="FAD_binding_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04954">
        <property type="entry name" value="SIP"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="1">
        <location>
            <begin position="14"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="275" mass="30165" checksum="968F1C35B5EF7367" modified="2016-02-17" version="1">MQDTSSELAVVRVRHPLKLRLLRVDRVEPVTPHLLRVVLSGEDLADFVSASFDDHVKVLFPAPGQERPTMPTLGPAGFVFADGVERPPVRDFTPRRFDPAARELELEFALHEAGPASDWARQARAGDWLGIGGPRGSRVVPAGFAWHLLIGDDTAMPAIARRLQELPATARAIAVLEVEDASARIDFASAAALQTQWCYRNGADPAGDPPLLRAVRELRWPHDRDAGYVWAAGETSAIRAVRQHLLSERGVDKARLHAAGYWKRGAQGAHEPLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBT7</accession>
    <name>A0A0S2DBT7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribbon-helix-helix protein, CopG family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_08165</name>
        <name evidence="2" type="ORF">GLE_0630</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000017">
        <property type="protein sequence ID" value="OPD64390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946174.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000017.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55988">
        <property type="protein sequence ID" value="ALN55988"/>
        <property type="gene ID" value="GLE_0630"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64390">
        <property type="protein sequence ID" value="OPD64390"/>
        <property type="gene ID" value="BV903_08165"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0630"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.620"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002145">
        <property type="entry name" value="CopG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01402">
        <property type="entry name" value="RHH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RHH_1" evidence="1">
        <location>
            <begin position="7"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="70" mass="8260" checksum="09EFA385B309F733" modified="2016-02-17" version="1">MKHQRMTLSLEAGEMAELEQMAKRGNSNKTEVIRRAVRIHMLLEQMRSEGKELHVQDQPDSRQLERLVFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBY2</accession>
    <name>A0A0S2DBY2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP synthase subunit b</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">ATP synthase F(0) sector subunit b</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">ATPase subunit I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">F-type ATPase subunit b</fullName>
            <shortName evidence="13">F-ATPase subunit b</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 16" type="primary">atpF</name>
        <name evidence="17" type="ORF">BV903_08400</name>
        <name evidence="19" type="ORF">D9T17_23730</name>
        <name evidence="18" type="ORF">FE772_04110</name>
        <name evidence="16" type="ORF">GLE_0685</name>
    </gene>
    <organism evidence="16 20">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="16 20" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 20">C3</strain>
        </source>
    </reference>
    <reference evidence="17 21" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 21">B25</strain>
        </source>
    </reference>
    <reference evidence="19 22" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 22">OH11</strain>
        </source>
    </reference>
    <reference evidence="18 23" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 23">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.</text>
    </comment>
    <comment type="function">
        <text evidence="11 13">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13 14">Belongs to the ATPase B chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000017">
        <property type="protein sequence ID" value="OPD64430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000061">
        <property type="protein sequence ID" value="ROU04432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946214.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000061.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0685"/>
    <dbReference type="EnsemblBacteria" id="ALN56043">
        <property type="protein sequence ID" value="ALN56043"/>
        <property type="gene ID" value="GLE_0685"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64430">
        <property type="protein sequence ID" value="OPD64430"/>
        <property type="gene ID" value="BV903_08400"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0685"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.673"/>
    <dbReference type="OMA" id="FAWKPIL"/>
    <dbReference type="OrthoDB" id="1999641at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01398">
        <property type="entry name" value="ATP_synth_b_bprime"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028987">
        <property type="entry name" value="ATP_synth_B-like_membr_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002146">
        <property type="entry name" value="ATP_synth_b/b'su_bac/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005864">
        <property type="entry name" value="ATP_synth_F0_bsu_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00430">
        <property type="entry name" value="ATP-synt_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81573">
        <property type="entry name" value="SSF81573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01144">
        <property type="entry name" value="ATP_synt_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 13 14" id="KW-0138">CF(0)</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 13 14" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 13 14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 13 14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="47"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ALN56043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OPD64430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="QCW24976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ROU04432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="156" mass="17264" checksum="6CD48B48654FC513" modified="2016-02-17" version="1">MNINMTFFGQMITFAILIWFTMKFIWPPLNKAIEERQQKIAQGLANAEGAEVLIQQARAQADEIVREARVKANEVVEQAHSRANQIVDQAKTDAMVEGTRLKALADAEIAAAADRAREDLRKQVSALAVTGAEKLLKREIDANAHKALLDELAAEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-06-17" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC44</accession>
    <name>A0A0S2DC44_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0742</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56100">
        <property type="protein sequence ID" value="ALN56100"/>
        <property type="gene ID" value="GLE_0742"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0742"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.730"/>
    <dbReference type="OrthoDB" id="2182508at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="118" mass="12952" checksum="29CA6EFF35B75969" modified="2016-02-17" version="1">MDGCHFHIEILAPSGLSGIEAHLADCAMPLQPYRSGFNDQVILRHGGDIDEFEFAMDPSTTGLLHASGSIFREESQAWRMVESLSRALRLAGFAHRAGMDNAAGNGLFREIDYRWGGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD90</accession>
    <name>A0A0S2DD90_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4442 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_06030</name>
        <name evidence="1" type="ORF">GLE_1095</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946522.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1095"/>
    <dbReference type="EnsemblBacteria" id="ALN56453">
        <property type="protein sequence ID" value="ALN56453"/>
        <property type="gene ID" value="GLE_1095"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1095"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1082"/>
    <dbReference type="OMA" id="AVCFKAP"/>
    <dbReference type="OrthoDB" id="1814691at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027961">
        <property type="entry name" value="DUF4442"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14539">
        <property type="entry name" value="DUF4442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="158" mass="17388" checksum="86B1DA60A53CC918" modified="2016-02-17" version="1">MSANVLALYKKLTRYPAGHWLFSRAVCMKAPYFGSIKPRFESLEPNRCTATIKHRRAVTNHLGTVHAIAMCNLAELTGGVMTDVSIPKSMRWIPIGMQVEYLKKAVGTLRAVATPAAPIVESDAPYDLPVNVEIANSAGEPVFRARIAMRVSPKPQRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDM7</accession>
    <name>A0A0S2DDM7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_1066</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946498.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1066"/>
    <dbReference type="EnsemblBacteria" id="ALN56424">
        <property type="protein sequence ID" value="ALN56424"/>
        <property type="gene ID" value="GLE_1066"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1066"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1054"/>
    <dbReference type="OMA" id="ISEAMRW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594978" evidence="2">
        <location>
            <begin position="26"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="3">
        <location>
            <begin position="79"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="419" mass="43368" checksum="579E1694D594824C" modified="2016-02-17" version="1">MSFHFLLPAALAAAVAGSLAAPAVAAPTAAAPARTTTYSYVYRYSGDGAPQVLAQLAPEPPRSGAYPRGAMPQPAPFGPVLISDNQRRPQLGVILAPDARSGVSILAVTPGSAAARAGLHSGDRLLAVDGRKIAGADGEARLGNARELLGALKLGQPARILYQRGKQEATLEVEPQAGERVMMFRNADGSRYVLNTEMRSMRIDRDGRAGVGEAGVAVAPGLRTEIYRIGPDLDCAGNDKDKRAACNMPLISEAMRWNGLNLASVDPKLGRYFGAQRGVLVISAPLELKGLEAGDVIQSVDGRAVDTPREAMDALRGKREGAQVEIGYLRDRANAKLKLTVPKAVAWVPPPPPPAPPAPPAPPTAPVPPAPAVAPPAPPAPPPPPPPPPAPPKGKVASAPPAPPAPVQLARGAQGYRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDP0</accession>
    <name>A0A0S2DDP0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946663.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1290"/>
    <dbReference type="EnsemblBacteria" id="ALN56647">
        <property type="protein sequence ID" value="ALN56647"/>
        <property type="gene ID" value="GLE_1290"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1290"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1273"/>
    <dbReference type="OMA" id="QLKIERC"/>
    <dbReference type="OrthoDB" id="2090294at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="172" mass="18153" checksum="1F0EACB90D13A752" modified="2016-02-17" version="1">MRDSDVPVKTNEGRDEIEHRTRKLPPMLRSILLIVDGERSARHLRELAVSLHGPADALEQLEQLGLIASSAAVAASLAATPRAPAAASSAGAAAPAPAASASPQRYQALYALMSEAVREHLGLRGYFLQLKIERCANSDELAALLPELSAALAKVRKDDVAARIEAQFAAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDQ3</accession>
    <name>A0A0S2DDQ3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipolytic enzyme, G-D-S-L family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">SGNH/GDSL hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_07000</name>
        <name evidence="3" type="ORF">GLE_1303</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946673.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1303"/>
    <dbReference type="EnsemblBacteria" id="ALN56660">
        <property type="protein sequence ID" value="ALN56660"/>
        <property type="gene ID" value="GLE_1303"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1303"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1286"/>
    <dbReference type="OMA" id="RYAMIFE"/>
    <dbReference type="OrthoDB" id="1247435at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726723" evidence="1">
        <location>
            <begin position="24"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH_hydro" evidence="2">
        <location>
            <begin position="205"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="414" mass="44236" checksum="22A25CD312783078" modified="2016-02-17" version="1">MNPLLRSFAAAALALSLLAPAYAAEPAHWVGTWTASPQATWDAGFVLPNNAPDRLRDQTVRQVARISVGGTRVRIALSNAYGREPVVIGAARVARSLGGSRIDAGSDRALTFGGRAEVTLLPGAPVLSDPVELSAPALAELAVSLYLPQDTALRSFHWEGGQDAYLARGDRSAQAALDGADTVSSRPYLSGIYVESARPLRTVVAFGDSITDGAASSINRNHRWPDFLAQRLASRDIAVLNAGISGAQVLNDGMGVNALARFERDVLAQRPDSVVLLMGINDIGWPGSSFEPAREAMSAQRLIGGYRQLIARARQAGVRIIGATLTPFEHALPDAPVKRYFNPQKERVRQQVNAWIRDSGEFDAVADFDALLRDPAHPASMQAAFDSGDRLHPGDAGYRAMADSLDETVLFGAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDQ9</accession>
    <name>A0A0S2DDQ9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Elongation factor G</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">fusA</name>
        <name evidence="10" type="ORF">FE772_06980</name>
        <name evidence="9" type="ORF">GLE_1297</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946669.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1297"/>
    <dbReference type="EnsemblBacteria" id="ALN56654">
        <property type="protein sequence ID" value="ALN56654"/>
        <property type="gene ID" value="GLE_1297"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1297"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1280"/>
    <dbReference type="OrthoDB" id="88967at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004540">
        <property type="entry name" value="Transl_elong_EFG/EF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00484">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="8">
        <location>
            <begin position="12"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW25447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="686" mass="73251" checksum="DC91ED77FA4EC0B9" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE05</accession>
    <name>A0A0S2DE05_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1334</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56691">
        <property type="protein sequence ID" value="ALN56691"/>
        <property type="gene ID" value="GLE_1334"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1334"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1316"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="81" mass="9193" checksum="7644F768316190AD" modified="2016-02-17" version="1">MRCRGRGSHRSYSRIRNSTIVIPAKAGIHVDVAAAFAVIDVSRDDKPPSKAFVRKRPSYFLLSARQKKVAKEKRLFKVKSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEA0</accession>
    <name>A0A0S2DEA0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acyl-peptide hydrolase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Acylaminoacyl-peptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLE_1469</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S9C family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1469"/>
    <dbReference type="EnsemblBacteria" id="ALN56826">
        <property type="protein sequence ID" value="ALN56826"/>
        <property type="gene ID" value="GLE_1469"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1469"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1450"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002471">
        <property type="entry name" value="Pept_S9_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002469">
        <property type="entry name" value="Peptidase_S9B_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00930">
        <property type="entry name" value="DPPIV_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00708">
        <property type="entry name" value="PRO_ENDOPEP_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0007">Acetylation</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595045" description="Acyl-peptide hydrolase" evidence="7">
        <location>
            <begin position="25"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="domain" description="DPPIV_N" evidence="9">
        <location>
            <begin position="271"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="8">
        <location>
            <begin position="501"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00032284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN56826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="703" mass="76148" checksum="CF87F84F49717B44" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DED1</accession>
    <name>A0A0S2DED1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Exopolyphosphatase</fullName>
            <ecNumber evidence="3">3.6.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ppx</name>
        <name evidence="7" type="ORF">BV903_07045</name>
        <name evidence="8" type="ORF">FE772_08535</name>
        <name evidence="6" type="ORF">GLE_1646</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">C3</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[phosphate](n) + H2O = [phosphate](n-1) + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21528"/>
            <dbReference type="Rhea" id="RHEA-COMP:9859"/>
            <dbReference type="Rhea" id="RHEA-COMP:14279"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16838"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="3.6.1.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GppA/Ppx family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.11" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000013">
        <property type="protein sequence ID" value="OPD64640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946942.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1646"/>
    <dbReference type="EnsemblBacteria" id="ALN57003">
        <property type="protein sequence ID" value="ALN57003"/>
        <property type="gene ID" value="GLE_1646"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64640">
        <property type="protein sequence ID" value="OPD64640"/>
        <property type="gene ID" value="BV903_07045"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1646"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1625"/>
    <dbReference type="OMA" id="RISEGCY"/>
    <dbReference type="OrthoDB" id="1862004at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004309">
        <property type="term" value="F:exopolyphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006793">
        <property type="term" value="P:phosphorus metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022371">
        <property type="entry name" value="Exopolyphosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003695">
        <property type="entry name" value="Ppx_GppA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030673">
        <property type="entry name" value="PyroPPase_GppA_Ppx"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02541">
        <property type="entry name" value="Ppx-GppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001267">
        <property type="entry name" value="Pyrophosphatase_GppA_Ppx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03706">
        <property type="entry name" value="exo_poly_only"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ppx-GppA" evidence="5">
        <location>
            <begin position="31"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD64640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW25707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="509" mass="55749" checksum="878F80ABAE759103" modified="2016-02-17" version="1">MNNVFPTSRLPLEDGDLLAAVDMGSNSFHMVVARYVLGQLRTVDRLRETVRMAEGLDRKGGLAPEVRQRALECLSRFGQRIRDVPPQRVRAIATNTVRRLAAPQAFLMPAESALGHAIEVVSGREEARLIYLGVAHAQPSKPGERRLVIDIGGGSTECIVGAGFEAIERESLQVGCIASTRRFFDNGKLSKKKWRDALNEVSAEFQQFAGTYRSLGWHEALGSSGTNKAIGEICAAMKLTKGAVTAEALPVLRDELLRADRIEAIDLPGLSSDRRPVIAGGILILEAAFNVLGLQRMAISKAAMREGVLYDMLGRGGADDPRDAAVASLVKRYGIDEPQSKRVEATLLRLFDQVAKAWNLDADDRLMLLRAARLHELGLAIAHSQYHVHSSYVIENSDISGFSRQQQQFLAALVRTHRRSIPKSAFDALPDRLLSAVRRSSALLRLAVLLHRAHESDPIPQLDAHAEGNTLTLTVSRRWLDSRPLVRADLEGEPQDMAGLGISLKLLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEG7</accession>
    <name>A0A0S2DEG7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56964">
        <property type="protein sequence ID" value="ALN56964"/>
        <property type="gene ID" value="GLE_1607"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1607"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="45" mass="4770" checksum="3D32DB2B92E5796E" modified="2016-02-17" version="1">MRERREPRPRKRSHAETRAASGNPAVAACAAPTAGCAGYGTDSRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEN4</accession>
    <name>A0A0S2DEN4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Molybdopterin synthase catalytic subunit</fullName>
            <ecNumber evidence="4">2.8.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">MPT synthase subunit 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Molybdenum cofactor biosynthesis protein E</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Molybdopterin-converting factor large subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Molybdopterin-converting factor subunit 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">moaE</name>
        <name evidence="12" type="ORF">FE772_08660</name>
        <name evidence="11" type="ORF">GLE_1672</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-NH-CH2-C(O)SH + cyclic pyranopterin phosphate + H2O = 2 [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-Gly + 4 H(+) + molybdopterin</text>
            <dbReference type="Rhea" id="RHEA:26333"/>
            <dbReference type="Rhea" id="RHEA-COMP:12160"/>
            <dbReference type="Rhea" id="RHEA-COMP:12202"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58698"/>
            <dbReference type="ChEBI" id="CHEBI:59648"/>
            <dbReference type="ChEBI" id="CHEBI:90619"/>
            <dbReference type="ChEBI" id="CHEBI:90778"/>
            <dbReference type="EC" id="2.8.1.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MoaE family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.12" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946965.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1672"/>
    <dbReference type="EnsemblBacteria" id="ALN57029">
        <property type="protein sequence ID" value="ALN57029"/>
        <property type="gene ID" value="GLE_1672"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1672"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1651"/>
    <dbReference type="OMA" id="WPLQRVS"/>
    <dbReference type="OrthoDB" id="1877633at2"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030366">
        <property type="term" value="F:molybdopterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00756">
        <property type="entry name" value="MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036563">
        <property type="entry name" value="MoaE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003448">
        <property type="entry name" value="Mopterin_biosynth_MoaE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02391">
        <property type="entry name" value="MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54690">
        <property type="entry name" value="SSF54690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00026066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN57029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW25729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="158" mass="17001" checksum="18CD62178C5448FC" modified="2016-02-17" version="1">MTDSDASASRSAAPEVRFALSAAAFEIAPLRAGLLSDQAGAYASFEGWVRDHHGGRAVLGLRYESYAELALSEGEKVLAEARERFAIVDARCVHRVGDLAIGELAVWVGVSAAHRDAAFAACRYIIDETKARVPIWKHERYADGEADWLHPLPPAAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEP3</accession>
    <name>A0A0S2DEP3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_06930</name>
        <name evidence="4" type="ORF">FE772_08420</name>
        <name evidence="2" type="ORF">GLE_1621</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000013">
        <property type="protein sequence ID" value="OPD64621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946927.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000013.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56978">
        <property type="protein sequence ID" value="ALN56978"/>
        <property type="gene ID" value="GLE_1621"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64621">
        <property type="protein sequence ID" value="OPD64621"/>
        <property type="gene ID" value="BV903_06930"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1621"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1602"/>
    <dbReference type="OrthoDB" id="2217515at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595029" evidence="1">
        <location>
            <begin position="32"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="92" mass="9977" checksum="0EDF0A101239541E" modified="2016-02-17" version="1">MQRNHRHRALRRAAVAALILAGCVFSLSSLALPVPPPNGGGWLIYTYYAKNESGQDVVVGMRYQGGCPGPQPHNSGVTTPRFTYQYVSCGQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DES9</accession>
    <name>A0A0S2DES9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1537</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Xanthomonadaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56894">
        <property type="protein sequence ID" value="ALN56894"/>
        <property type="gene ID" value="GLE_1537"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1537"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1519"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="144" mass="16341" checksum="4BC3E5B0B390E7F8" modified="2016-02-17" version="1">MATIPAPYCVSSDPAARRWWSELSEDSKHALIRSWGDDERADPIAATARRAATLLKHCLREQAHANRHWQPDDGLQPLHEHMAAQGIAPTRLHGWPDPPIARHSQIYDHGMIWNIKYAQGRWDIHTEWCSADARALAERWAASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF90</accession>
    <name>A0A0S2DF90_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cell envelope integrity protein CreD</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Inner membrane protein CreD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">creD</name>
        <name evidence="3" type="ORF">FE772_08470</name>
        <name evidence="2" type="ORF">GLE_1632</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1632"/>
    <dbReference type="EnsemblBacteria" id="ALN56989">
        <property type="protein sequence ID" value="ALN56989"/>
        <property type="gene ID" value="GLE_1632"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1632"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1612"/>
    <dbReference type="OMA" id="RVHPIQY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010364">
        <property type="entry name" value="Uncharacterised_IM_CreD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30092">
        <property type="entry name" value="PTHR30092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06123">
        <property type="entry name" value="CreD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004548">
        <property type="entry name" value="CreD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="325"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="376"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="405"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="479" mass="51779" checksum="9E5B29E6979AC63B" modified="2016-02-17" version="1">MRVWLKMLMVLGLTLAILVPLLMIGGVIDERQGYRAQAVATVARSYAGAQAFSGPALIVPYEDTWISEEKDEKGVIKRVAHREQGRWTYFPGKLEVEGELLPRERRLGLYKVLVYEWQGKAKAGFVANIPADPVAEPGMTVNGIARTIGKPWISYGFADVRGLRDPKLRLDGLDAAVEDGLGARDGGGIHARLGAPAAATQLKVQTELEFTLGGTESLAVVPLGKDNRFSLRSKWPHPNYGGSFPPSSDSIGNDGFRADWRVSSVATNAQRQYLAGVTLPTVGLSGRGDEGPEAAAEIGSEINAIQVTLKDPVNVYSQADRATKYGLLFVLLTFVGFFMFELIKQLRIHPIQYGLVGLALAIFFLLLVSLSEHIEFGLSYLIASVACIGLLVFYLSAVLRSVPRALGFGAMLVTLYGALYGLLISEDNALALGAGLLFAILAAIMVITRKVDWYQLGASAPKRREAAVPPPLPERDAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF97</accession>
    <name>A0A0S2DF97_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Phosphoglycolate phosphatase</fullName>
            <shortName evidence="10">PGP</shortName>
            <shortName evidence="10">PGPase</shortName>
            <ecNumber evidence="5 10">3.1.3.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">gph</name>
        <name evidence="12" type="ORF">BV903_16940</name>
        <name evidence="11" type="ORF">GLE_1818</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">B25</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>2-phosphoglycolate + H2O = glycolate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14369"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29805"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58033"/>
            <dbReference type="EC" id="3.1.3.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Organic acid metabolism; glycolate biosynthesis; glycolate from 2-phosphoglycolate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.18" evidence="5 10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000046">
        <property type="protein sequence ID" value="OPD62630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947069.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000046.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1818"/>
    <dbReference type="EnsemblBacteria" id="ALN57170">
        <property type="protein sequence ID" value="ALN57170"/>
        <property type="gene ID" value="GLE_1818"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62630">
        <property type="protein sequence ID" value="OPD62630"/>
        <property type="gene ID" value="BV903_16940"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1818"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1789"/>
    <dbReference type="OMA" id="TPHAKPH"/>
    <dbReference type="OrthoDB" id="1484726at2"/>
    <dbReference type="UniPathway" id="UPA00865">
        <property type="reaction ID" value="UER00834"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008967">
        <property type="term" value="F:phosphoglycolate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046295">
        <property type="term" value="P:glycolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00495">
        <property type="entry name" value="GPH_hydrolase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006346">
        <property type="entry name" value="PGPase/MupP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037512">
        <property type="entry name" value="PGPase_prok"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01449">
        <property type="entry name" value="PGP_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 10 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="16"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN57170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OPD62630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="228" mass="24055" checksum="6A79B5A48B127A3E" modified="2016-02-17" version="1">MSATPAAAFPQAALFDLDGTLLDSAPDMLATANAMRAARGRGPMPLEALRPHVSKGARAMLGAAFADVDAGERETWVPEFLDTYERELGLHGAPFPGVEAMLAALEAAGRPWGIVTNKPEYLARKLMPLLGWDTRCAVLIGGDTLAARKPDPLPLTVAAQRIGVEPGACAYVGDDERDILAARAAGMPSVVALWGYRLEMDDPIAWQGDVLVDDPAALAAADAWPATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFC0</accession>
    <name>A0A0S2DFC0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3228 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_10080</name>
        <name evidence="1" type="ORF">GLE_1984</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947189.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1984"/>
    <dbReference type="EnsemblBacteria" id="ALN57334">
        <property type="protein sequence ID" value="ALN57334"/>
        <property type="gene ID" value="GLE_1984"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1984"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1949"/>
    <dbReference type="OMA" id="VHRNWTS"/>
    <dbReference type="OrthoDB" id="1232035at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021610">
        <property type="entry name" value="DUF3228"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38666">
        <property type="entry name" value="PTHR38666"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11539">
        <property type="entry name" value="DUF3228"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="185" mass="21329" checksum="613CF763620AC182" modified="2016-02-17" version="1">MTIILTDFARPRLFPREPRRNTIQDITAEEFERHLNEVPPLMVLDGYAPFCKLHVHRNWTSTRCLAVPITDENRHLLCSGYDARTKDELPVLTRWFENIDPPVAEYLIAILYSREQLAKEGTRTDADWGVVGCMYTAEPMETPMAPITMMRNALGVEEGGSGVELDREAYRRSVEFWSARANWRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFM5</accession>
    <name>A0A0S2DFM5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2033</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947230.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2033"/>
    <dbReference type="EnsemblBacteria" id="ALN57383">
        <property type="protein sequence ID" value="ALN57383"/>
        <property type="gene ID" value="GLE_2033"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2033"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1998"/>
    <dbReference type="OMA" id="DFEIGTW"/>
    <dbReference type="OrthoDB" id="1994921at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595098" evidence="1">
        <location>
            <begin position="34"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="202" mass="22103" checksum="FF49AB551013D476" modified="2016-02-17" version="1">MPPLQVARRPTSALYAGALAALLALAWPPACLAQAAATPAATQRDGQRDFDFETGRWRTHVRRLAQSPGAAPRWLEYTGTTRVVAVHGGRANLAELAVAGPAGRIDGVALRLYEPATRQWRIHYANLGDGALTAPLAGRFVDGRGKFFGDDRIDGRPVRVRFRIHCPRPDRCLFEQAVSADGGRRWQVNWLATDTRLRESAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFN0</accession>
    <name>A0A0S2DFN0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Aminotransferase, classes I, II, and III/beta-eliminating lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_10625</name>
        <name evidence="2" type="ORF">GLE_2101</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947280.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2101"/>
    <dbReference type="EnsemblBacteria" id="ALN57451">
        <property type="protein sequence ID" value="ALN57451"/>
        <property type="gene ID" value="GLE_2101"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2101"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2065"/>
    <dbReference type="OMA" id="GTDIGRQ"/>
    <dbReference type="OrthoDB" id="479874at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="59"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="414" mass="46516" checksum="B1CB7A80F54891EB" modified="2016-02-17" version="1">MDSRALIELERQPFKQRLAFQYSLYLNEVEQGFMTGREGFGPVDRRMKYKDLNSDQFNDVLVFGSNSYLGLSNDPYVKAKVIEAVEKYGIGSGGSPAFSGYTRQHKELEQRLAALAGHEDAVLLPGGYMANLCWVNGLMNRNDIIVYDKNSHASVINAIKMTNVPFYTFDPERLEEFEKLIVRIKQKAKPGVQIFSTVEGVRSIDGTIIELKQYLEICRAHDIIVILDDAHGLGTVGKHGRGTLEHLDLMGQVDLRMSTCSKAIGAQGAFVSGSKEHIFLLRNFSYPYLFTSGLAQPTIAAISAALDVIEREPERIERLHENVRYMQDQLEAQGMRIIRGDSGIIPVFFSEDGVVRKINRALYRRGLFANIMEYPMVPPGLERLRLSVMATHTHEEIDTAVEMIAQVAREHGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFS0</accession>
    <name>A0A0S2DFS0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2019</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2019"/>
    <dbReference type="ESTHER" id="lysen-a0a0s2dfs0">
        <property type="family name" value="PHAZ7_phb_depolymerase"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57369">
        <property type="protein sequence ID" value="ALN57369"/>
        <property type="gene ID" value="GLE_2019"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2019"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1984"/>
    <dbReference type="OMA" id="GYNDCEL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002918">
        <property type="entry name" value="Lipase_EstA/Esterase_EstB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32015">
        <property type="entry name" value="PTHR32015"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01674">
        <property type="entry name" value="Lipase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595106" evidence="1">
        <location>
            <begin position="35"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="377" mass="39452" checksum="810F0868350F2F34" modified="2016-02-17" version="1">MFRSTLNWIGASAASLALAAAGGLAALAPGAAHALDCGANNGYTCQGAASQYAGGFNPGVGSGGFGGGDCVATRTPVVFIAGNGDSAISFDMPPAAVSGYATPANSVYDELKARGYNDCELFGITYLDADERGAPQYNYHQPAKYQILKTFIDKVKLYTGRGQVDIVAHSLGSSMALAMLRYHGYQASVRRFVNIGGGLRGLQTCLSTGYQSPYAPTCNAEAYVFPYDYYTFGLYPSTGVAFYGYNRWTGSGSNSLRAMPAIYSSIAFYTITAGRYDQIQCFTTSYSAGCADSALFAAASNLKAQVDIGFGSAAYAYDWDWSDGSPYNIGGGDTSSGVGHFRSKTNAGRIVYNMLATTCTTGCANGYVGVNGPAVNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFS9</accession>
    <name>A0A0S2DFS9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Efflux RND transporter permease subunit</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Multidrug resistance protein mdtC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mdtC</name>
        <name evidence="5" type="ORF">FE772_10675</name>
        <name evidence="4" type="ORF">GLE_2110</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947289.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57460">
        <property type="protein sequence ID" value="ALN57460"/>
        <property type="gene ID" value="GLE_2110"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2110"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2074"/>
    <dbReference type="OMA" id="PGIVGQF"/>
    <dbReference type="OrthoDB" id="145346at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="463"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="523"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="837"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="871"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="895"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="939"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="970"/>
            <end position="993"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="1021" mass="110089" checksum="1F91E9C55FB8D622" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFY6</accession>
    <name>A0A0S2DFY6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57360">
        <property type="protein sequence ID" value="ALN57360"/>
        <property type="gene ID" value="GLE_2010"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2010"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="57" mass="6320" checksum="269C154A3574C095" modified="2016-02-17" version="1">MRARAGESECEHQRGDDAARRAAWMRRRGGGKGIRHGSASLRRDGVRRAPCRSRCAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFY8</accession>
    <name>A0A0S2DFY8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosome-binding factor A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 4" type="primary">rbfA</name>
        <name evidence="5" type="ORF">BV903_08695</name>
        <name evidence="6" type="ORF">FE772_10985</name>
        <name evidence="4" type="ORF">GLE_2177</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">C3</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RbfA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000018">
        <property type="protein sequence ID" value="OPD64369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947340.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2177"/>
    <dbReference type="EnsemblBacteria" id="ALN57526">
        <property type="protein sequence ID" value="ALN57526"/>
        <property type="gene ID" value="GLE_2177"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64369">
        <property type="protein sequence ID" value="OPD64369"/>
        <property type="gene ID" value="BV903_08695"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2177"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2139"/>
    <dbReference type="OMA" id="GDLQHCK"/>
    <dbReference type="OrthoDB" id="1971380at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00003">
        <property type="entry name" value="RbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000238">
        <property type="entry name" value="RbfA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023799">
        <property type="entry name" value="RbfA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020053">
        <property type="entry name" value="Ribosome-bd_factorA_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33515">
        <property type="entry name" value="PTHR33515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02033">
        <property type="entry name" value="RBFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89919">
        <property type="entry name" value="SSF89919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00082">
        <property type="entry name" value="rbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01319">
        <property type="entry name" value="RBFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="111"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD64369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW26117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="136" mass="15373" checksum="2DD62EA946444230" modified="2016-02-17" version="1">MPSKSFHRTDRVSAQLRRELGTLVREAVREHGLPSVSVSDVEISRDLAHAKVFVTALQPERSAEAVKALKELSRELRFQLGRAMKLRHVPELHFHYDDSVDRGERIEHLLREAPAATEDADGEAPQDGEDRSRDAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG23</accession>
    <name>A0A0S2DG23_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SsrA-binding protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Small protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">smpB</name>
        <name evidence="6" type="ORF">BV903_23045</name>
        <name evidence="8" type="ORF">D9T17_13570</name>
        <name evidence="7" type="ORF">FE772_11210</name>
        <name evidence="5" type="ORF">GLE_2224</name>
    </gene>
    <organism evidence="5 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 9">C3</strain>
        </source>
    </reference>
    <reference evidence="6 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">OH11</strain>
        </source>
    </reference>
    <reference evidence="7 12" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="3">The tmRNA-SmpB complex associates with stalled 70S ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SmpB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000078">
        <property type="protein sequence ID" value="OPD61542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000033">
        <property type="protein sequence ID" value="ROU06475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947376.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2224"/>
    <dbReference type="EnsemblBacteria" id="ALN57573">
        <property type="protein sequence ID" value="ALN57573"/>
        <property type="gene ID" value="GLE_2224"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61542">
        <property type="protein sequence ID" value="OPD61542"/>
        <property type="gene ID" value="BV903_23045"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2224"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2189"/>
    <dbReference type="OMA" id="WTNHSAR"/>
    <dbReference type="OrthoDB" id="1720952at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070929">
        <property type="term" value="P:trans-translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09294">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00023">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023620">
        <property type="entry name" value="SmpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000037">
        <property type="entry name" value="SsrA-bd_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020081">
        <property type="entry name" value="SsrA-bd_prot_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30308">
        <property type="entry name" value="PTHR30308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01668">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74982">
        <property type="entry name" value="SSF74982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00086">
        <property type="entry name" value="smpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01317">
        <property type="entry name" value="SSRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="136"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="138"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD61542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW26153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROU06475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="169" mass="19207" checksum="9BC8EF498EFF2C4B" modified="2016-02-17" version="1">MAKTNNKTAKDKAKGGAGGTIAQNKRARHEYHLEENFEAGLELQGWELKSIRAGRANITDAYAVVLRGEIYLIGAQIVPLISASTHVVAEERRSRKLLLHRKEIDNLIGRVQRDGYTVIPTALYWKGNRVKAGLSLAKGKQSHDKREASKERDWEREKQRVMRRHNRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG41</accession>
    <name>A0A0S2DG41_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alpha-2-macroglobulin family N-region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_2115</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947292.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2115"/>
    <dbReference type="EnsemblBacteria" id="ALN57465">
        <property type="protein sequence ID" value="ALN57465"/>
        <property type="gene ID" value="GLE_2115"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2115"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2079"/>
    <dbReference type="OMA" id="QAYAIYI"/>
    <dbReference type="OrthoDB" id="231654at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004866">
        <property type="term" value="F:endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011625">
        <property type="entry name" value="A2M_N_BRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021868">
        <property type="entry name" value="Alpha_2_Macroglob_MG3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041203">
        <property type="entry name" value="Bact_A2M_MG5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041246">
        <property type="entry name" value="Bact_MG10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001599">
        <property type="entry name" value="Macroglobln_a2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002890">
        <property type="entry name" value="MG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00207">
        <property type="entry name" value="A2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07703">
        <property type="entry name" value="A2M_BRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17973">
        <property type="entry name" value="bMG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11974">
        <property type="entry name" value="bMG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17972">
        <property type="entry name" value="bMG5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01835">
        <property type="entry name" value="MG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01360">
        <property type="entry name" value="A2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01359">
        <property type="entry name" value="A2M_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="A2M_N_2" evidence="4">
        <location>
            <begin position="1055"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="domain" description="A2M" evidence="5">
        <location>
            <begin position="1260"/>
            <end position="1350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="352"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1852"/>
            <end position="1908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1858"/>
            <end position="1874"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1971" mass="213842" checksum="E6B70EF3E9BC3FA6" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGB4</accession>
    <name>A0A0S2DGB4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase, group 1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2246</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947396.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2246"/>
    <dbReference type="EnsemblBacteria" id="ALN57595">
        <property type="protein sequence ID" value="ALN57595"/>
        <property type="gene ID" value="GLE_2246"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2246"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2211"/>
    <dbReference type="OMA" id="GNMGRCH"/>
    <dbReference type="OrthoDB" id="1591999at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13579">
        <property type="entry name" value="Glyco_trans_4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="18"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="222"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="418" mass="46390" checksum="C4F579F33EA523DB" modified="2016-02-17" version="1">MRILFLTDNFPPEGNAPATRTYEHAVRWVRAGHEVTVITCAPNFPEGKLFPGYRNAWRSVETLDGIRVVRVKTYITANEGFLKRTLDYLSFMAAGTVAGLFERRHDVVVATSPQFFCALGGWALARLKRRPFVFELRDLWPASITAVGAMQRSAAIRALEKLEMFLYRSADAIVPVTQSFREELVHRGVRADKIHVVLNGVDLQRYCPAARDQAMAKQYDLDGRFVVGYLGTHGMAHGLEKVIEAAERLRDDPRIVFFFAGSGAQRAHVERMAAERALPNVRMIPRQPKEMMPRLWGLCDLSLIPLRDTPVFASVIPSKLFEGMGMGIPALMSLPRGEAVRIVESTGCGVCVAPENAAAMADEIAALAGDPERMRRLREASLAAAPAYSRDRQARLMSDALARLVDDDGARGLLRTPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGP5</accession>
    <name>A0A0S2DGP5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HNH endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_12190</name>
        <name evidence="2" type="ORF">GLE_2439</name>
    </gene>
    <organism evidence="2 4">
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        <dbReference type="NCBI Taxonomy" id="69"/>
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            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW26312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2439"/>
    <dbReference type="EnsemblBacteria" id="ALN57788">
        <property type="protein sequence ID" value="ALN57788"/>
        <property type="gene ID" value="GLE_2439"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2439"/>
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    <dbReference type="OMA" id="HYGAVCM"/>
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    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="309" mass="34319" checksum="7FA27290EC68DD38" modified="2016-02-17" version="1">MNEDKQRIAEWRAKRRQQRFEQDLEQRRTRKFAGYFFLSEDEEESIDPADAAADAEEQALAQRRSALAEAPPRLSSSEVRLALWSWDMDALRELWSEREQKLTYIEDAARLLAHIRYRSGIDATLRSPAQMMDNDAIEALKGSLEERGRLSPASPISPLPPDAAVDGKRVGQVLRVIREGQADFRRRLVEHYGAVCMVTGTSHASVIDAAHIKPYNGVSTNTLGNGLLLRKDIHALFDAGLLDISPDLLVSISDAVTDTSYRALDGQRLTLRAPSKISPAALLARIRGEAMSEIGGTSAIPEDIHGHSR</sequence>
</entry>
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    <organism evidence="3 4">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1484" mass="161816" checksum="4B04CB83ACB37A78" modified="2016-02-17" version="1"> </sequence>
</entry>
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    <accession>A0A0S2DGU3</accession>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="225" mass="25853" checksum="5179CF540724E340" modified="2016-02-17" version="1">MQAAMRGEPSFWRRNGLSLVLAAIFVVFLLGQVLTGQAAWNEEIAREGRAPLTLWAYLDSGHFISATFENWESEFLQMGMYVLLTVWLRQMGSAESRPFEPRPFEPQPEDIEPGPAPWPVRRGGLWRRLYAHSLTAAFLLLFLGSFALHGYGSWRHHNDERRLQGRAPVELSEHLRSSDFWFESFQNWQSEFLAVLSIVVLSIFLREDKSPESKPVRAPHRQTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
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    <name>A0A0S2DGU5_LYSEN</name>
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        <submittedName>
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        </submittedName>
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    <gene>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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        <property type="gene ID" value="GLE_2421"/>
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    </dbReference>
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        <source>
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        </source>
    </evidence>
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        <source>
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        <source>
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        </source>
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        <source>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
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        </submittedName>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">YC36</strain>
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        <property type="gene ID" value="GLE_2486"/>
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    <evidence type="ECO:0000313" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26346.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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    </evidence>
    <sequence length="82" mass="8815" checksum="99ADFA1B4211992F" modified="2016-02-17" version="1">MRLQLHQTLDADAMRGITAAVLRADIGSRINFERDLERGAPIVRVENWLTVAETVEAIARSGYSVAAIVDASNDAPGGHASR</sequence>
</entry>
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    <accession>A0A0S2DGX5</accession>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
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    </evidence>
    <sequence length="44" mass="4794" checksum="ECB8177A180C937C" modified="2016-02-17" version="1">MSRSRQAGRRPRGRGLGRPATTSMGAQKSCLPCMRGPRPAENPR</sequence>
</entry>
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    <accession>A0A0S2DGZ1</accession>
    <name>A0A0S2DGZ1_LYSEN</name>
    <protein>
        <submittedName>
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        <submittedName>
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        <submittedName>
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    <gene>
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            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
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        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="OPD65684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="BV903_01415"/>
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        <location>
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            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
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            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD65684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26331.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <location>
            <begin position="6"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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        </source>
    </evidence>
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</entry>
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    <accession>A0A0S2DHA4</accession>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="protein sequence ID" value="ALN57789"/>
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    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2440"/>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="94" mass="10325" checksum="B590355CA77E4574" modified="2016-02-17" version="1">MPRKSDLAPPQEGVVMPVDAFKALSAFQQELHGIVRTLQPEVLIEIGYPAGQDHRLLREVFQALARRLDPVMDACVWTPTGDEAAGPAGARRLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHF1</accession>
    <name>A0A0S2DHF1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2235 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2770</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947800.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58118">
        <property type="protein sequence ID" value="ALN58118"/>
        <property type="gene ID" value="GLE_2770"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2770"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2727"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018712">
        <property type="entry name" value="DUF2235"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09994">
        <property type="entry name" value="DUF2235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2235" evidence="2">
        <location>
            <begin position="48"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="454"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="454"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="502" mass="54606" checksum="A8148667A2B472F0" modified="2016-02-17" version="1">MGGGKNPDGVRTDPANQQQMDSYVQASQALSQLQAPVLLDSADPHSRMFVACFDGTGNSMYGTDPKNHTNVADVAKQLQNGLHANIGVGYVEGPGTQSGWYERTVDGATGRSFDPRLEKMYAQFIEQAKEWKAEDPQAKISLAGIGYSRGAEQEAAFSRLVHERGIQDPAGAVYVKDKDGNITAPPTYRNAPLEPPGQVAQAVGLFDPVGTGEPRKHDRRLPPSVMSGFQVTAQDERRDQFKSTSILREGHTEDQRFLNVTVGGAHSNIGGSYELNGLSIRSGNLMVDYLNSLSDQPYLQKRAEPNDPKLNVVHRSDQHQVFYTTFGFRDGERDRIETVASKQQVKDHSVADPNRKEAIDEDMSARFARRPVPIGPAPGGQEPAIVQGGLGAQGPAALGQGGTAQGNDFERNFARMIDAARNGDAAAFRDATRDHAQAPETQNWLQAGRERYQQLNAEQAQQPQQAQPQQAQVRQQPEPADAQRLPPPQPDAPAQPPRAPGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DID0</accession>
    <name>A0A0S2DID0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2805</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58153">
        <property type="protein sequence ID" value="ALN58153"/>
        <property type="gene ID" value="GLE_2805"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2805"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2762"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="55" mass="6133" checksum="200249E4259A5EF0" modified="2016-02-17" version="1">MKPGARAVAARAQALGMVRPPAGPAGAPTRSPLSFRFFRVRRMRRRRPANPLFYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DID3</accession>
    <name>A0A0S2DID3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Nucleoside diphosphate kinase</fullName>
            <shortName evidence="2">NDK</shortName>
            <shortName evidence="2">NDP kinase</shortName>
            <ecNumber evidence="2 4">2.7.4.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Nucleoside-2-P kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 6" type="primary">ndk</name>
        <name evidence="7" type="ORF">FE772_14525</name>
        <name evidence="6" type="ORF">GLE_2911</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 4">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:44640"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:18113"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the NDK family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.6" evidence="2 4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947902.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2911"/>
    <dbReference type="EnsemblBacteria" id="ALN58259">
        <property type="protein sequence ID" value="ALN58259"/>
        <property type="gene ID" value="GLE_2911"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2911"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2873"/>
    <dbReference type="OMA" id="KIVAMKM"/>
    <dbReference type="OrthoDB" id="1752581at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006241">
        <property type="term" value="P:CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006165">
        <property type="term" value="P:nucleoside diphosphate phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006228">
        <property type="term" value="P:UTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00451">
        <property type="entry name" value="NDP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023005">
        <property type="entry name" value="Nucleoside_diP_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="SSF54919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00469">
        <property type="entry name" value="NDP_KINASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 2" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NDK" evidence="5">
        <location>
            <begin position="3"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="active site" description="Pros-phosphohistidine intermediate" evidence="2">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW26685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="141" mass="15365" checksum="B95E3951F9A846D8" modified="2016-02-17" version="1">MALERTLSIIKPDAVAKNVIGEIYTRFEKAGLKVVASKMKHLSKQEAEGFYAVHRERPFFAALVEFMISGPVVIQALQGENAVLKHRELMGATNPKDAAPGTIRADFADSIDANAVHGSDSLENAAIEIAYFFPGTDVYAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIH2</accession>
    <name>A0A0S2DIH2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2699</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58047">
        <property type="protein sequence ID" value="ALN58047"/>
        <property type="gene ID" value="GLE_2699"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2699"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2658"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="47" mass="4660" checksum="D2B5BEAA83C38A25" modified="2016-02-17" version="1">MATMRSRLAPECAGEGAGAGSPVAAGAGFALKPRATAIAAARRARYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIP9</accession>
    <name>A0A0S2DIP9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Asparagine synthase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="10">Asparagine synthase (Glutamine-hydrolyzing)</fullName>
            <ecNumber evidence="10">6.3.5.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">asnB</name>
        <name evidence="10" type="ORF">FE772_15250</name>
        <name evidence="9" type="ORF">GLE_3051</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asparagine synthetase family.</text>
    </comment>
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    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948007.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3051"/>
    <dbReference type="EnsemblBacteria" id="ALN58398">
        <property type="protein sequence ID" value="ALN58398"/>
        <property type="gene ID" value="GLE_3051"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3051"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3011"/>
    <dbReference type="OMA" id="IEHSHQP"/>
    <dbReference type="OrthoDB" id="610569at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_Synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00712">
        <property type="entry name" value="AsnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006426">
        <property type="entry name" value="Asn_synth_AEB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033738">
        <property type="entry name" value="AsnB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001589">
        <property type="entry name" value="Asn_synthetase_glu-h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01536">
        <property type="entry name" value="asn_synth_AEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="10" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="8">
        <location>
            <begin position="2"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="5">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="384"/>
            <end position="385"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for beta-aspartyl-AMP intermediate formation" evidence="7">
        <location>
            <position position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN58398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW26798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="659" mass="72321" checksum="0F16D1DB660B7E8E" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ04</accession>
    <name>A0A0S2DJ04_LYSEN</name>
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        <submittedName>
            <fullName evidence="9">Biopolymer transporter ExbD</fullName>
        </submittedName>
        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BV903_14485</name>
        <name evidence="10" type="ORF">FE772_15170</name>
        <name evidence="8" type="ORF">GLE_3034</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
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            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
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    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
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    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD63192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW26783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_MTAY01000037.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3034"/>
    <dbReference type="EnsemblBacteria" id="ALN58381">
        <property type="protein sequence ID" value="ALN58381"/>
        <property type="gene ID" value="GLE_3034"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD63192"/>
        <property type="gene ID" value="BV903_14485"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3034"/>
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    <dbReference type="OMA" id="AMIRIVI"/>
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        <property type="component" value="Chromosome"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD63192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW26783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="153" mass="16518" checksum="F1D320BA8F768B60" modified="2016-02-17" version="1">MRIRDRRADDEPEINLVPLIDVILVLIIFFVVTATFDARSVLKLELPRATGEPSGDASQALVVLVNAEGRYFVGDREVLRDDLESLKTTIAEVAGDDRDRTVMLRADARTPYQAVVTVYDALGQLGFRKIMSATAPPPGAAARPAAAPAGASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJA8</accession>
    <name>A0A0S2DJA8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_3159</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3159"/>
    <dbReference type="EnsemblBacteria" id="ALN58505">
        <property type="protein sequence ID" value="ALN58505"/>
        <property type="gene ID" value="GLE_3159"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3159"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3115"/>
    <dbReference type="OMA" id="QPEFDRT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010917">
        <property type="entry name" value="TonB_rcpt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01156">
        <property type="entry name" value="TONB_DEPENDENT_REC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0798">TonB box</keyword>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="47"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="379"/>
            <end position="978"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
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</entry>
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</entry>
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        </source>
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</entry>
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        </submittedName>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN58803">
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        <property type="gene ID" value="GLE_3458"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3458"/>
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    </dbReference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="ALN58803.1"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW27084.1"/>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJX6</accession>
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        <submittedName>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">C3</strain>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="100" mass="11161" checksum="901BD6B1E8241F3C" modified="2016-02-17" version="1">MIFGAAAFSFWSAGRAAAERAEVVGRDACRAAGVQWLDQSVHAIGLRVIRRESGWLGFERTFRFDYSIDGEDRHIGRLVLRGDRLVAFSGPVTREPSQLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJX7</accession>
    <name>A0A0S2DJX7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallo-beta-lactamase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3485</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3485"/>
    <dbReference type="EnsemblBacteria" id="ALN58830">
        <property type="protein sequence ID" value="ALN58830"/>
        <property type="gene ID" value="GLE_3485"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3485"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3430"/>
    <dbReference type="OMA" id="YLDGMIW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046116">
        <property type="entry name" value="DUF6053"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10996">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19523">
        <property type="entry name" value="DUF6053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01027">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="74"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-Casp" evidence="2">
        <location>
            <begin position="309"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="518" mass="56845" checksum="6B71DA6043F25A2C" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK06</accession>
    <name>A0A0S2DK06_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3277</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58623">
        <property type="protein sequence ID" value="ALN58623"/>
        <property type="gene ID" value="GLE_3277"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3277"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3230"/>
    <dbReference type="OMA" id="CARRRFV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5016454299" evidence="2">
        <location>
            <begin position="39"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="163" mass="17615" checksum="214E5E65546FECFD" modified="2016-02-17" version="1">MEDTATPTGCGCARRRFVPTIALPLALCALAVAPGAFASGHMPGFPIPPRSFADYAACKAFLEQTARDDRARAEPQPRETEPGVTRQTLVISDGVTESGEHQAAYRVQVGAQFRRRDEARESIVTTFSYDENSYRCNGGELSGESGARGYYLPGYEPIPAPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK17</accession>
    <name>A0A0S2DK17_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">DNA mismatch repair protein MutS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 12" type="primary">mutS</name>
        <name evidence="12" type="ORF">GLE_3238</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9 10">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948145.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3238"/>
    <dbReference type="EnsemblBacteria" id="ALN58584">
        <property type="protein sequence ID" value="ALN58584"/>
        <property type="gene ID" value="GLE_3238"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3238"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3191"/>
    <dbReference type="OMA" id="TPMMAQY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00096">
        <property type="entry name" value="MutS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005748">
        <property type="entry name" value="DNA_mismatch_repair_MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017261">
        <property type="entry name" value="DNA_mismatch_repair_MutS/MSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007861">
        <property type="entry name" value="DNA_mismatch_repair_MutS_clamp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="PTHR11361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05190">
        <property type="entry name" value="MutS_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="SSF48334"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53150">
        <property type="entry name" value="SSF53150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55271">
        <property type="entry name" value="SSF55271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01070">
        <property type="entry name" value="mutS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 9 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 9 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_MISMATCH_REPAIR_2" evidence="11">
        <location>
            <begin position="698"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="624"/>
            <end position="631"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN58584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="872" mass="95486" checksum="08C4561E267263C2" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK43</accession>
    <name>A0A0S2DK43_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_17595</name>
        <name evidence="1" type="ORF">GLE_3572</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948389.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3572"/>
    <dbReference type="EnsemblBacteria" id="ALN58916">
        <property type="protein sequence ID" value="ALN58916"/>
        <property type="gene ID" value="GLE_3572"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3572"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3516"/>
    <dbReference type="OMA" id="CPMTFQE"/>
    <dbReference type="OrthoDB" id="937913at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="375" mass="43217" checksum="7A3A0DDD1B79A78B" modified="2016-02-17" version="1">MTTLIVSDPWDIHARSVAWALENEGERVHVWYTHDYPQKHGVSLRTGGGPAAVSLYCLRHERAFDTADVDTVWLRRWYQPEPSAQLHPADIRFSQLESTEFVRATINLLEAQRERFWINPIQAKALADRKAVQLHHAAAVGLDTPPTLISNDPEAIRAFYREHGGRAIYKPITAAAWISEEEEKVRGTFTTPLTEQLLREDAALSNAPGIYQPLLDKAYELRVTVMGRTAIAARLHSQRDGDYLTDWRANEFDERMGCERYALPEAVQARCLQVMARLGLVFGCIDIVVTRDGRYVFLEVNEMGQFMWLEAINPGLQLMDCAVEFIRSRDPAFVYDWREPVYRYRDYWESRGERGEAEPDARRHVPLPQVFQMRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKA2</accession>
    <name>A0A0S2DKA2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phenazine biosynthesis protein PhzF family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3733</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhzF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948508.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3733"/>
    <dbReference type="EnsemblBacteria" id="ALN59077">
        <property type="protein sequence ID" value="ALN59077"/>
        <property type="gene ID" value="GLE_3733"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3733"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3678"/>
    <dbReference type="OMA" id="IVNGMSQ"/>
    <dbReference type="OrthoDB" id="1468060at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003719">
        <property type="entry name" value="Phenazine_PhzF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774">
        <property type="entry name" value="PTHR13774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02567">
        <property type="entry name" value="PhzC-PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016184">
        <property type="entry name" value="PhzC_PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00654">
        <property type="entry name" value="PhzF_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR016184-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="293" mass="31063" checksum="C8F1D89A641FB9D0" modified="2016-02-17" version="1">MTQRRYLQLDVFADRPGAGNPLAVVLDAEGLDDAAMQAIARWTRLPETTFVFAPTQPGASYRIRMFSPRREVPFAGHPSVGTACVVLEAGLAAPVDGVLVQEGVAGLLPLSVSGEGEARTIAVRTPRARVVETADAADPRLAAALRGLPLGALPPALMDGGRRWWLAQLRDEAALRAAQPDWAAIGGLAESTESMGLCAFARADAGQDYDLVVRAFVGAPAQFEDAASGAANATLAAWLKHNDALPGRDGRYTVSQGREVGFDARLQLRVDADGEVWSGGRVSNVVRGQIDWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKD1</accession>
    <name>A0A0S2DKD1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">PhoH family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_17805</name>
        <name evidence="5" type="ORF">GLE_3618</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhoH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948420.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3618"/>
    <dbReference type="EnsemblBacteria" id="ALN58962">
        <property type="protein sequence ID" value="ALN58962"/>
        <property type="gene ID" value="GLE_3618"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3618"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3562"/>
    <dbReference type="OMA" id="NLCGQFD"/>
    <dbReference type="OrthoDB" id="445854at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003714">
        <property type="entry name" value="PhoH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02562">
        <property type="entry name" value="PhoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoH" evidence="4">
        <location>
            <begin position="112"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW27208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="328" mass="35935" checksum="76B9C29E5193BB90" modified="2016-02-17" version="1">MPVRTASEFTLDPADSERLANLSGPFDGHLRMIELRLGVEIANRGNIFRIDGPDGAVGRAEKLLRRLWKDAAEETLDDNAIHLALTESGAELAVQQDFEPQEVAIRVKRGTIRGRGANQAKYLHAIATHDINFGIGPAGTGKTFLAVASAVEALNESRVQRLILVRPAVEAGEKLGFLPGDLTQKVDPYLRPLYDALYEMFGVEKVVKLLEKNVIEIAPLAYMRGRTLNDAYVILDEAQNTTIEQMKMFLTRIGYGSTAVVTGDLTQVDLPKHVKSGLKDALDVLRNVDGISFTFFEAKDVVRHPMVARIVSAYDARDAKDAQTGPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKD4</accession>
    <name>A0A0S2DKD4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Alpha-lytic protease prodomain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLE_3668</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948456.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3668"/>
    <dbReference type="EnsemblBacteria" id="ALN59012">
        <property type="protein sequence ID" value="ALN59012"/>
        <property type="gene ID" value="GLE_3668"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3668"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3612"/>
    <dbReference type="OMA" id="SSAGHNC"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.50">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037295">
        <property type="entry name" value="Alpha-lytic_protease_prodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004236">
        <property type="entry name" value="Pept_S1_alpha_lytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001316">
        <property type="entry name" value="Pept_S1A_streptogrisin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035070">
        <property type="entry name" value="Streptogrisin_prodomain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02983">
        <property type="entry name" value="Pro_Al_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001134">
        <property type="entry name" value="Streptogrisin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00861">
        <property type="entry name" value="ALYTICPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54806">
        <property type="entry name" value="SSF54806"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 10" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595296" evidence="8">
        <location>
            <begin position="27"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="Pro_Al_protease" evidence="9">
        <location>
            <begin position="124"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="354"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="360"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="349"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="307"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="343"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001134-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001134-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="405" mass="42279" checksum="0D2C15E47E79C599" modified="2016-02-17" version="1">MPHASVRASALSILGLLALSAHTAHARPPAVPAERASNPGVGVVAAVPRDAEVSPDRARQRWRAQRDAVAGEAAARRALGEDFAGSWIESGPGGGYRLIVASAGAARTNVAGVEIRPVARDWRRLQASKQHLDQALQSRRPGLHKPLTGLYTWHVDPASNRVVVRIARDAQAQAVDFVAASGADADALRFEYLDGAPQTTNWIFGGLSYITAYGGGCTAGFVAYKAGVPGVVTAGHCGKAPDRIDVDWSGIGRTPFGEFVHSRFPTADRGWIASSSSFAVSPQIYDWAGNYITVKGSIEAPVGATVCRAGPKTGYRCGQITAKQVTVNYPQGAVYGMTESNACSGFGDSGGPWIDGGGQAQGIQSGNQGNSSAGHNCDAPAAQRKSWFDPLNSILGEYGLVLTTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKH7</accession>
    <name>A0A0S2DKH7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter, ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_3609</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3609"/>
    <dbReference type="EnsemblBacteria" id="ALN58953">
        <property type="protein sequence ID" value="ALN58953"/>
        <property type="gene ID" value="GLE_3609"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3609"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3553"/>
    <dbReference type="OMA" id="QEFNVDR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="21"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="53"/>
            <end position="60"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="333" mass="35727" checksum="6534AF9210767B87" modified="2016-02-17" version="1">MSAVAGARETAASATAEAPAIRARGMSKRFGELQAVDRVDLTVPRACVYGFLGPNGSGKSTTIRMLCGLLTPSAGEIEVLGLKIPEQAEALRRRIGYMTQKFSLFEDLSVRENLEFLAAVQDIPKAAARKRIDALIGQYRFGDRQDQLAGTMSGGQKQRLALAGAVIHEPELLFLDEPTSAVDPESRRDFWEKLFELADAGTTLLVSTHYMDEAERCHRLAILDRGVLVADGTPAELTGELRGRAVEVRAAQPRKAQRALVDLPGVLSVAQIGNDLRVLLADADTAEQGLTDALRAAGLQAEVAKAKPNLEDVFVAATRGDAPRAAAAREEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKM7</accession>
    <name>A0A0S2DKM7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3633</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58977">
        <property type="protein sequence ID" value="ALN58977"/>
        <property type="gene ID" value="GLE_3633"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3633"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3577"/>
    <dbReference type="OMA" id="RLMVGIP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007423">
        <property type="entry name" value="Sel_put"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38453">
        <property type="entry name" value="PTHR38453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04328">
        <property type="entry name" value="Sel_put"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="74" mass="8688" checksum="C11E7EFC23C2CC25" modified="2016-02-17" version="1">MMGTALVPVGQYQSFKRAWRRIVQTARLCCGVPDYDNYVRHLMEKHPERPIPDYATFFRERQEARYGGGRFGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKT2</accession>
    <name>A0A0S2DKT2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA-directed RNA polymerase subunit beta'</fullName>
            <shortName evidence="7">RNAP subunit beta'</shortName>
            <ecNumber evidence="7">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">RNA polymerase subunit beta'</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Transcriptase subunit beta'</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">rpoC</name>
        <name evidence="11" type="ORF">BV903_21070</name>
        <name evidence="12" type="ORF">FE772_18680</name>
        <name evidence="10" type="ORF">GLE_3796</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">C3</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7 8">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000067">
        <property type="protein sequence ID" value="OPD61933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948560.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000067.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3796"/>
    <dbReference type="EnsemblBacteria" id="ALN59140">
        <property type="protein sequence ID" value="ALN59140"/>
        <property type="gene ID" value="GLE_3796"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61933">
        <property type="protein sequence ID" value="OPD61933"/>
        <property type="gene ID" value="BV903_21070"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3796"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3740"/>
    <dbReference type="OMA" id="YRNIRVE"/>
    <dbReference type="OrthoDB" id="4421at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01322">
        <property type="entry name" value="RNApol_bact_RpoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012754">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="PTHR19376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02386">
        <property type="entry name" value="rpoC_TIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RPOLA_N" evidence="9">
        <location>
            <begin position="235"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="462"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="464"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="814"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="889"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="896"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="899"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OPD61933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW27367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="1407" mass="155097" checksum="1D1D15D5B01DC9AF" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKZ4</accession>
    <name>A0A0S2DKZ4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptide methionine sulfoxide reductase MsrA</fullName>
            <shortName evidence="4">Protein-methionine-S-oxide reductase</shortName>
            <ecNumber evidence="4">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Peptide-methionine (S)-S-oxide reductase</fullName>
            <shortName evidence="4">Peptide Met(O) reductase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">msrA</name>
        <name evidence="6" type="ORF">GLE_3889</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionine = [thioredoxin]-dithiol + L-methionine (S)-S-oxide</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3889"/>
    <dbReference type="EnsemblBacteria" id="ALN59232">
        <property type="protein sequence ID" value="ALN59232"/>
        <property type="gene ID" value="GLE_3889"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3889"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3828"/>
    <dbReference type="OMA" id="AGPFYYA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033744">
        <property type="term" value="F:L-methionine:thioredoxin-disulfide S-oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="SSF55068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PMSR" evidence="5">
        <location>
            <begin position="53"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="221" mass="23907" checksum="A37C5DAD15812801" modified="2016-02-17" version="1">MAGSFIPGIGAFKQRMPQREDALPGRDTPLPLHNAHYLSGAKLRDAYPGLARVQFGLGCFWGAERKFWSLPGVAVTAVGYSGGYTPNPTYREVCSGQTGHAETVLVVYDPAKIAFEALLKVFWESHDPTQGMRQGNDAGTQYRSAIYCEDDSQYRAALASRDAFQAKLREAGFGEITTEIAAPPAPEFYYAEDDHQQYLAKNPAGYCGLGGTGVSCPIGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL59</accession>
    <name>A0A0S2DL59_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4024</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59366">
        <property type="protein sequence ID" value="ALN59366"/>
        <property type="gene ID" value="GLE_4024"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4024"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3961"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="37" mass="4022" checksum="5D61F84EE136B5F3" modified="2016-02-17" version="1">MHAEFCAAHLSELLFMITAAAKHAGLFGRFGVMEVLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLB5</accession>
    <name>A0A0S2DLB5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cobyrinic Acid a,c-diamide synthase</fullName>
            <ecNumber evidence="5">6.3.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">cobB</name>
        <name evidence="5" type="ORF">GLE_4088</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CobB/CobQ family. CobQ subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4088"/>
    <dbReference type="EnsemblBacteria" id="ALN59430">
        <property type="protein sequence ID" value="ALN59430"/>
        <property type="gene ID" value="GLE_4088"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4088"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4030"/>
    <dbReference type="OMA" id="QPFKCGP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042242">
        <property type="term" value="F:cobyrinic acid a,c-diamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004484">
        <property type="entry name" value="CbiA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011698">
        <property type="entry name" value="GATase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43873">
        <property type="entry name" value="PTHR43873"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07685">
        <property type="entry name" value="GATase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GATase_3" evidence="4">
        <location>
            <begin position="213"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="404" mass="42969" checksum="4682294CFB3CC4F7" modified="2016-02-17" version="1">MARWHSRQGRRVRVFKTGPDFLDPMVLERASGAPAQQLDLWMCGEDDVRARLHAAASEADLILIEGVMGLFDGSPSSADLAQRIGVPVLTVIDGSAMAQTFGALALGLVRYREGLRVYGVAANRIGSAYHAQLLRESLPGELRWLGALPRDPALALPERHLGLVAAGELGDIDARLDALADAWAAHADAELPPAVAFEPAQAPAVPPRLHGRRIAVARDAAFCFLYPANLELLRAAGAELAFFSPVAGETLPECDAAWLPGGYPELHLDALAANAALRDALHAHVAAGKPLLAECGGLLYCLDELTDRDGRGAAMAGLLRGRARIGTRLAALGLQSVALPEGELRGHTFHYAQAEVAAQAIAMSANPNGGPSREAVYRRDRMSASFVHFYFPSNPDAAVRLFQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLK5</accession>
    <name>A0A0S2DLK5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_24680</name>
        <name evidence="4" type="ORF">FE772_19525</name>
        <name evidence="2" type="ORF">GLE_3979</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000097">
        <property type="protein sequence ID" value="OPD61241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948689.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000097.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3979"/>
    <dbReference type="EnsemblBacteria" id="ALN59321">
        <property type="protein sequence ID" value="ALN59321"/>
        <property type="gene ID" value="GLE_3979"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61241">
        <property type="protein sequence ID" value="OPD61241"/>
        <property type="gene ID" value="BV903_24680"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3979"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3917"/>
    <dbReference type="OMA" id="QGRQEVI"/>
    <dbReference type="OrthoDB" id="1751290at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595399" evidence="1">
        <location>
            <begin position="30"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="169" mass="18625" checksum="DBD7B3C91AA7DFB2" modified="2016-02-17" version="1">MSAIAVPLPRRLAVALALTACLAAPAALAQQKIQQQMSAEQFKSAGLNKLDDQELANLNAWLNRTLDTETSKAVVKAQEETAHERRGFFDKSPSREPVVARMTGRFEGFSRGQTYVLDNGQEWRQDDSADLPGVKLDSPQVRIAPSVIGNAWYLSVQGYNTRAKVVRVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLN6</accession>
    <name>A0A0S2DLN6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_20435</name>
        <name evidence="1" type="ORF">GLE_4167</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948843.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59509">
        <property type="protein sequence ID" value="ALN59509"/>
        <property type="gene ID" value="GLE_4167"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4167"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4109"/>
    <dbReference type="OMA" id="AHIRIHP"/>
    <dbReference type="OrthoDB" id="1706771at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="289" mass="31369" checksum="5F32EFA09F4CD5CA" modified="2016-02-17" version="1">MSFFSKLFGRKPAAPAAAQVLDLQAFSQRFAGALRDAFPDAHIRIHPGAQHEARIELALADGIRANLQVGNAYQRYLNAPEDLEATLADQIASAREVQRQLSAEDAQAGEGVVLPVIKTRAWHEVAMRQLGASQPQAASPFVIEPLAGDLVVTYVLDTPASMSFLSPEQAAQRELHGPALRAHALDNLARRLPELEIKGGDGRYAARLDRNYDAGMALLFERWRERVSLRGEPVFAIAARDELLMCGSDDGENLASLRGIAQEIAGSSAYGLSAGLFVWRDGGLRAFED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM00</accession>
    <name>A0A0S2DM00_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">recQ</name>
        <name evidence="14" type="ORF">FE772_19545</name>
        <name evidence="13" type="ORF">GLE_3985</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">C3</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948693.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3985"/>
    <dbReference type="EnsemblBacteria" id="ALN59327">
        <property type="protein sequence ID" value="ALN59327"/>
        <property type="gene ID" value="GLE_3985"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3985"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3922"/>
    <dbReference type="OMA" id="HHDIPKS"/>
    <dbReference type="OrthoDB" id="54580at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006293">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002121">
        <property type="entry name" value="HRDC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044876">
        <property type="entry name" value="HRDC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032284">
        <property type="entry name" value="RecQ_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018982">
        <property type="entry name" value="RQC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00570">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16124">
        <property type="entry name" value="RecQ_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09382">
        <property type="entry name" value="RQC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00341">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00956">
        <property type="entry name" value="RQC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="SSF47819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01389">
        <property type="entry name" value="recQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50967">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 13" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="26"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="215"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="HRDC" evidence="10">
        <location>
            <begin position="536"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="503"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN59327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW27505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="610" mass="67051" checksum="0DBB73809067302D" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM34</accession>
    <name>A0A0S2DM34_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_4047</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4047"/>
    <dbReference type="EnsemblBacteria" id="ALN59389">
        <property type="protein sequence ID" value="ALN59389"/>
        <property type="gene ID" value="GLE_4047"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4047"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3990"/>
    <dbReference type="OMA" id="IPGNKMA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002327">
        <property type="entry name" value="Cyt_c_1A/1B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11961">
        <property type="entry name" value="PTHR11961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00604">
        <property type="entry name" value="CYTCHRMECIAB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594955" evidence="6">
        <location>
            <begin position="18"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="7">
        <location>
            <begin position="24"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="125" mass="13171" checksum="06A2C075FA56F14F" modified="2016-02-17" version="1">MPATMMSIAIALFPAVASSTGPAPSAQEGKQHFIRCAACHSTNAADRSATGPHLNGIVGRAAASLPHFAYASELRGQDFKWSPARLDAFLESPRTTHPGMCPTFNGLAKAEHRAALIAYLQQPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM42</accession>
    <name>A0A0S2DM42_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">[Ribosomal protein S18]-alanine N-acetyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.266</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rimI</name>
        <name evidence="8" type="ORF">BV903_04240</name>
        <name evidence="10" type="ORF">D9T17_07770</name>
        <name evidence="9" type="ORF">FE772_20585</name>
        <name evidence="7" type="ORF">GLE_4198</name>
    </gene>
    <organism evidence="7 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 11">C3</strain>
        </source>
    </reference>
    <reference evidence="8 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">OH11</strain>
        </source>
    </reference>
    <reference evidence="9 14" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acetylates the N-terminal alanine of ribosomal protein S18.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>acetyl-CoA + N-terminal L-alanyl-[ribosomal protein bS18] = CoA + H(+) + N-terminal N(alpha)-acetyl-L-alanyl-[ribosomal protein bS18]</text>
            <dbReference type="Rhea" id="RHEA:43756"/>
            <dbReference type="Rhea" id="RHEA-COMP:10676"/>
            <dbReference type="Rhea" id="RHEA-COMP:10677"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:64718"/>
            <dbReference type="ChEBI" id="CHEBI:83683"/>
            <dbReference type="EC" id="2.3.1.266"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the acetyltransferase family. RimI subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.266" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000008">
        <property type="protein sequence ID" value="OPD65211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000020">
        <property type="protein sequence ID" value="ROU07671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057950266.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000020.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4198"/>
    <dbReference type="EnsemblBacteria" id="ALN59540">
        <property type="protein sequence ID" value="ALN59540"/>
        <property type="gene ID" value="GLE_4198"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65211">
        <property type="protein sequence ID" value="OPD65211"/>
        <property type="gene ID" value="BV903_04240"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4198"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4140"/>
    <dbReference type="OMA" id="GERYLNY"/>
    <dbReference type="OrthoDB" id="1826274at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008999">
        <property type="term" value="F:ribosomal protein S5-alanine N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017189">
        <property type="term" value="P:N-terminal peptidyl-alanine acetylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02210">
        <property type="entry name" value="RimI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006464">
        <property type="entry name" value="AcTrfase_RimI/Ard1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043690">
        <property type="entry name" value="RimI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01575">
        <property type="entry name" value="rimI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="6">
        <location>
            <begin position="16"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD65211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW27676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROU07671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="164" mass="18077" checksum="FE930D2D2CA5473A" modified="2016-02-17" version="1">MSALAPDLEDASAAPAGLRPMREDDLDAVHAIEIRAYEFPWTPGIFRDCLRADYPSWVLTDAGRVIGYFLMSVAAGEAHVLNVCVAPEAHGRGHGRRLLRALLRIARGRGAERVFLEVRPSNPGAIALYHSEGFNEIGRRPRYYPARGGREDALVMAIELLAQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM69</accession>
    <name>A0A0S2DM69_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ABC transporter ATP-binding protein/permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="11">Abc transporter protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FE772_21275</name>
        <name evidence="11" type="ORF">GLE_4353</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948985.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4353"/>
    <dbReference type="EnsemblBacteria" id="ALN59694">
        <property type="protein sequence ID" value="ALN59694"/>
        <property type="gene ID" value="GLE_4353"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4353"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4292"/>
    <dbReference type="OMA" id="VTEWRTH"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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            <begin position="192"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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            <end position="296"/>
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        </location>
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            <end position="335"/>
        </location>
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        <location>
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            <end position="603"/>
        </location>
    </feature>
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            <end position="25"/>
        </location>
    </feature>
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            <begin position="402"/>
            <end position="409"/>
        </location>
        <ligand>
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        </ligand>
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        <source>
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        </source>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN59694.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW27798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="613" mass="67439" checksum="79F251D9E8CDC3FC" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMA3</accession>
    <name>A0A0S2DMA3_LYSEN</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4360</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="375" mass="41231" checksum="3D542E48B1325325" modified="2016-02-17" version="1">MSPPQLSALALNRALLARQSLLERSAQSPLAMVERLLGLQAQAPNPPYLGLWTRLQDFALDDLTQAMRERRIVRATMMRGTLHLVGADDYRALRPVLQPVLQRLSLASGHAKALKGLDLHALRRAGFDALRAAPLSATALGEALRAQWPQHDCDELARLVRNLEPLVHVPPAGTWDWHKPAAFATALDWLGAAIADAPDEDAVDAMALRYLGAFGPASARDLAAWSGLAATNQRLQRLRSRLCVFRDEDGSELFDLPDAPRPPPELPAPPRLLPEFDNVLLAHARRARILDEALRPAVFSRNGLVAATVLVDGFVAGVWKLQRDARTAVLTISPFRRLAAAERAELEAQAADCLRVVAADRERHEIHFARVQRPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMB5</accession>
    <name>A0A0S2DMB5_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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            <taxon>Proteobacteria</taxon>
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    </organism>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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        <property type="gene ID" value="GLE_4097"/>
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    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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            <end position="457"/>
        </location>
    </feature>
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            <begin position="469"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="491" mass="52481" checksum="D6505F3E53AA61D1" modified="2016-02-17" version="1">MNPTPRTADPAATRPRAFAPAVAALLFAALALAAVAWALVLASAPVTGPQPMRWQRADGSPPAPADAGGYPFRGCRLADVQLDMALWNGGAIVPCHDPALGSGWAFLDPRRRTATLRWPLADDGEAPLTLGLSPGPGRRLALVFQRAVEGDAFVGIAGADGWARAPEKLGRVRYLAAAWVGDRLELALVPLTGQDPHGLRGPVKVVGFDDAGRQERIAVRACGADCPTPPIAYRAGARWVFEYAGRARAEGGEPVAPAFPGRTLEDLDLDLVAQGRLRSPIGLSLGRGDTPAIGADGKPTLAAPAPWDGMRTVRQERFVVDVAPQRRAQWAEPSLRAITERAGARTLTWYTDERDRVHVTDARQPTIEAMAALPAVARWPQGLASRMFASDDAGGWWLVDSSGESIHLDRDLRRTDPLPLRQHLRDARGEIAVYALDWALFALPALSILCAGLSLCAAPRRPLLRARPLAIAALLYLPGAVWALLQVAPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMB9</accession>
    <name>A0A0S2DMB9_LYSEN</name>
    <protein>
        <submittedName>
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        </submittedName>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_21480</name>
        <name evidence="3" type="ORF">GLE_4397</name>
    </gene>
    <organism evidence="3 5">
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        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW27834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949020.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4397"/>
    <dbReference type="EnsemblBacteria" id="ALN59738">
        <property type="protein sequence ID" value="ALN59738"/>
        <property type="gene ID" value="GLE_4397"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4397"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4336"/>
    <dbReference type="OMA" id="ADWTHPI"/>
    <dbReference type="OrthoDB" id="1819702at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="89"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="225" mass="26181" checksum="5FDDB2C4B99EA3EF" modified="2016-02-17" version="1">MSLHLYSHPLASFCHKVLIALYENDTPFQAHLVDLADPAGKADFLERWPVGKMPVLRDEARGRTVPETSIIVEYLQQHYPGPRALLPDDADARLDVRLWDRFFDLYVQAPMQKIVADFMLKKKDQDDLGVSQARRTLQTAYDMIERQLADDWICGADFTLVDCAAAPALFYAEIVEPFHRHHPRLMAYLTRLMARPSYERVLFEARPYFHLYPFHELLPPGWVQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMF5</accession>
    <name>A0A0S2DMF5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fimbrial assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gspL</name>
        <name evidence="3" type="ORF">GLE_4175</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN59517">
        <property type="protein sequence ID" value="ALN59517"/>
        <property type="gene ID" value="GLE_4175"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4175"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4117"/>
    <dbReference type="OMA" id="IDRLTPW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
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        <property type="entry name" value="PilN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05137">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="395" mass="42416" checksum="596733FC0D69D026" modified="2016-02-17" version="1">MNSQVAEGRLAANRLRSLSARLAPGAGGFFSWWGRTLASWLPLRTRQALGVDRGRLLLQVDGGAQGGAIRLRLQQADQVQELATLPDLSAWNSGAPADAAADPLAPLLPPRIGELPRWLLLPPATSLRRRLNLPAAAADRLRDVVGFEIDRQTPFTAEAVAFDARVLARRDGDGQIEAELVAVPRQALDPQLQAIGPLAATLAGIDVAGADGVPLGVNLLPPAQRRARRDPFRYWNLALAAVALLALAAGMWQVLDNRRAAIKDLQQTIARNANAARQAASQRQEVVDLIEGQAFLDRTRAARPSTVQIIDELSRRMPDSTYLEKLAIEDESLLMIGLSREASSLIGKLQGTPLWRSPALTGAVQPDPATGRDRFTLTAEIGPPKAQNAEGARGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMN6</accession>
    <name>A0A0S2DMN6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_21965</name>
        <name evidence="3" type="ORF">GLE_4499</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59840">
        <property type="protein sequence ID" value="ALN59840"/>
        <property type="gene ID" value="GLE_4499"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4499"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4435"/>
    <dbReference type="OMA" id="FRGECYR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="146"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="5"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="270" mass="30443" checksum="106615D4FD039021" modified="2016-02-17" version="1">MTVNYDKENRKLQKLRVEIERLGADKFKIEQERDRLNSILAGMLHETRRLNLEINSFSEELSKCLASGDMVGVRENAESIMFASGLISSRLTFSDFELNPVSLARQGKIRAGIYKKFDKSRRLLAKSWRSKGISVRLEGLSYAEIDAVPAFELVPFVLLDNAIKYSPDNQDVKVLFEDRPNIDCHTRVTISSVGPMVSPEEIEKLTERGYRGGFAHGSRIAGEGLGLYLAEILSATANAKLKIFSSAENLYSFNGIPYSAFWVELDFFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMU3</accession>
    <name>A0A0S2DMU3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF484 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_03600</name>
        <name evidence="3" type="ORF">FE772_22135</name>
        <name evidence="1" type="ORF">GLE_4533</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000006">
        <property type="protein sequence ID" value="OPD65382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949127.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4533"/>
    <dbReference type="EnsemblBacteria" id="ALN59874">
        <property type="protein sequence ID" value="ALN59874"/>
        <property type="gene ID" value="GLE_4533"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65382">
        <property type="protein sequence ID" value="OPD65382"/>
        <property type="gene ID" value="BV903_03600"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4533"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4469"/>
    <dbReference type="OMA" id="FQVPFVS"/>
    <dbReference type="OrthoDB" id="1264777at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007435">
        <property type="entry name" value="DUF484"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38765">
        <property type="entry name" value="PTHR38765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04340">
        <property type="entry name" value="DUF484"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD65382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="227" mass="25289" checksum="A55F7C295F04E376" modified="2016-02-17" version="1">MSERSGDKPTELGAHEVAAWLRRHPRFLQHFPDLSMSLVVPREEGSAASLASYQLEVLRDKNRELSRRLHELFGNAQENERLAVRTHQLTLALMRQSNAGDTLRAMAASLAEDFNGDLVRLIVLRRYDGVADSEWLQTIEDGDARLQPFRDALADGEPLCGRLQPEKHAVLYADRAADVQSTALLPLPGVGLIAVGSRDANRFFPGMGTLFLRMMGESLAVALRRFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMU5</accession>
    <name>A0A0S2DMU5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59693">
        <property type="protein sequence ID" value="ALN59693"/>
        <property type="gene ID" value="GLE_4352"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4352"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4291"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="60" mass="6605" checksum="68152612CDDED27A" modified="2016-02-17" version="1">MQRRSPHGPAGTGGRARPARGAPRMPRRRRGFRARAAPARAFARFGTVFRRRRGAAPPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMY1</accession>
    <name>A0A0S2DMY1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3916 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_21495</name>
        <name evidence="1" type="ORF">GLE_4400</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949023.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59741">
        <property type="protein sequence ID" value="ALN59741"/>
        <property type="gene ID" value="GLE_4400"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4400"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4339"/>
    <dbReference type="OMA" id="SEFQKWI"/>
    <dbReference type="OrthoDB" id="1740500at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025075">
        <property type="entry name" value="DUF3916"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13079">
        <property type="entry name" value="DUF3916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="178" mass="19970" checksum="B7BFF3B720DA8888" modified="2016-02-17" version="1">MARSHPCKPLPYRLHALHELERWAAGFAGRFPSARELGEHPRYWNWKLPFDARLLQGENAAAQATRRECAQRLIDACAALLRTKPDWAAGVRVTCTICVPEVWGSELCIYLDEDYWRSHVEADASGVAAIVPIQGRSLASEWGLALPPGMLERGVECRSGDESAREEQWRYGEVARVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN25</accession>
    <name>A0A0S2DN25_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Phosphoribosylformylglycinamidine synthase</fullName>
            <shortName evidence="10">FGAM synthase</shortName>
            <shortName evidence="10">FGAMS</shortName>
            <ecNumber evidence="10">6.3.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Formylglycinamide ribonucleotide amidotransferase</fullName>
            <shortName evidence="10">FGAR amidotransferase</shortName>
            <shortName evidence="10">FGAR-AT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 15" type="primary">purL</name>
        <name evidence="15" type="ORF">GLE_4186</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide = 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17129"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="ChEBI" id="CHEBI:147287"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">In the N-terminal section; belongs to the FGAMS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.3" evidence="10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4186"/>
    <dbReference type="EnsemblBacteria" id="ALN59528">
        <property type="protein sequence ID" value="ALN59528"/>
        <property type="gene ID" value="GLE_4186"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4186"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4128"/>
    <dbReference type="OMA" id="LSANWMW"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00128"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004642">
        <property type="term" value="F:phosphoribosylformylglycinamidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00419">
        <property type="entry name" value="PurL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040707">
        <property type="entry name" value="FGAR-AT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010073">
        <property type="entry name" value="PurL_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041609">
        <property type="entry name" value="PurL_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036604">
        <property type="entry name" value="PurS-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18072">
        <property type="entry name" value="FGAR-AT_linker"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18076">
        <property type="entry name" value="FGAR-AT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82697">
        <property type="entry name" value="SSF82697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01735">
        <property type="entry name" value="FGAM_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3 10 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FGAR-AT_N" evidence="14">
        <location>
            <begin position="37"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="FGAR-AT_linker" evidence="13">
        <location>
            <begin position="163"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="12">
        <location>
            <begin position="420"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="12">
        <location>
            <begin position="894"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="780"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="873"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="1180"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="1301"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="1303"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="676"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="677"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="716"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="720"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="929"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="931"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF18072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF18076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ALN59528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1336" mass="143185" checksum="E236DADA518A5F87" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNJ6</accession>
    <name>A0A0S2DNJ6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4958</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60299">
        <property type="protein sequence ID" value="ALN60299"/>
        <property type="gene ID" value="GLE_4958"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4958"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4885"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="655"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="737"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="671"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="757"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="871"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="921"/>
            <end position="967"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="981" mass="103510" checksum="8713E4317C351F2A" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNQ9</accession>
    <name>A0A0S2DNQ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aminotransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Aminotransferase class I and II/beta-eliminating lyase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Pyridoxal phosphate-dependent aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_13935</name>
        <name evidence="4" type="ORF">FE772_23290</name>
        <name evidence="2" type="ORF">GLE_4788</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000035">
        <property type="protein sequence ID" value="OPD63384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949316.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4788"/>
    <dbReference type="EnsemblBacteria" id="ALN60129">
        <property type="protein sequence ID" value="ALN60129"/>
        <property type="gene ID" value="GLE_4788"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63384">
        <property type="protein sequence ID" value="OPD63384"/>
        <property type="gene ID" value="BV903_13935"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4788"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4721"/>
    <dbReference type="OMA" id="WRMGWII"/>
    <dbReference type="OrthoDB" id="554560at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="36"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="416" mass="45518" checksum="62A5F039F1EE2654" modified="2016-02-17" version="1">MSLPPLKTRERLSEVRYEIRGELARRARELEAQGRKQIKLNIGNPGAFGFRAPEHLQRAIAERIADTDPYTHQQGLPAAREAIAAFHKRRGTPNASPERVFVGNGVSELIDLSLRALLNPGDEVLLPSPDYPLWSAATILNDGRPVYYRCQPENGFLPDPDEIEQLVSSRTRAIVLINPNNPTGAAYPRELIERIVAIAAKHKLLLMCDEIYDSILYDGAQFVPVAPIAGDLPCLSFGGLSKVHRACGWRVGWAVLSGDPVASGDFHHAMDLLGALRLCANVPGQFAIEAALDGTDTITPLCRPGGRLFEARRAVVEAVEASRHLQLVVPAGALYAFPSVTGAAAQGFDDHQFALELLETEDVLVVPGSSFNVPYRNHFRVTLLPQPEDVREVFGRIERVLDRYAERAGAPRAAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNX3</accession>
    <name>A0A0S2DNX3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_03470</name>
        <name evidence="4" type="ORF">FE772_22015</name>
        <name evidence="2" type="ORF">GLE_4507</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000006">
        <property type="protein sequence ID" value="OPD65358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949107.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000006.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59848">
        <property type="protein sequence ID" value="ALN59848"/>
        <property type="gene ID" value="GLE_4507"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65358">
        <property type="protein sequence ID" value="OPD65358"/>
        <property type="gene ID" value="BV903_03470"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4507"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4443"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD65358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="98" mass="10166" checksum="45BEC3E90AEB16B5" modified="2016-02-17" version="1">MNQIGSFALFAMFWLVCGALLFAEGKPPLAILAGLVFMTLPYFASKWVQDRHAARAAAARKTAGRASGLAGSLVRDIGIAALAGAACLGLALWALLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNX6</accession>
    <name>A0A0S2DNX6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cellulose-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Chitin binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BV903_22250</name>
        <name evidence="6" type="ORF">GLE_4852</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000074">
        <property type="protein sequence ID" value="OPD61696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949360.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000074.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4852"/>
    <dbReference type="EnsemblBacteria" id="ALN60193">
        <property type="protein sequence ID" value="ALN60193"/>
        <property type="gene ID" value="GLE_4852"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61696">
        <property type="protein sequence ID" value="OPD61696"/>
        <property type="gene ID" value="BV903_22250"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4852"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4782"/>
    <dbReference type="OMA" id="MNHYMYD"/>
    <dbReference type="OrthoDB" id="1005693at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004302">
        <property type="entry name" value="Cellulose/chitin-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041029">
        <property type="entry name" value="GbpA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18416">
        <property type="entry name" value="GbpA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03067">
        <property type="entry name" value="LPMO_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595478" evidence="3">
        <location>
            <begin position="24"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-4" evidence="4">
        <location>
            <begin position="29"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="GbpA_2" evidence="5">
        <location>
            <begin position="233"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF18416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN60193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD61696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="399" mass="43406" checksum="47C3A82980F29073" modified="2016-02-17" version="1">MPRPAPLAPSLLALFALSFLCPAGDVRAHGSMVHPKSRIYACKQGDAENPSDPACRAAWQVSGSAMFYDWMSINRADADGRHRAVVPDGQLCSGGNPTFAGLDLARADWQAQPIAADANGRFAFLFKGTAPHATRAWTFYITRDGWNPERPLHWSDLEPFCTLGNVPLGSDGNYRLDCPLPKRSGRHVIYNTWQRSDSTEAFYTCMDVRFGAGSSPPPGGEPGTPPTRPGPQWNDAGALGLRGELAVGTVLTLRLFQADGRDAERIEVALGAGQTGAEAWPLRLAERVNAQSRYARVGVLEGGVVTPRAPAEANRVYLGGVARRFALETRTPAPQPGDRYDYAYPDGIGRYRPGETVVLGRDGKRYACRPFPQGGWCNIDHDAYRPGSGYAWQDAWIAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP36</accession>
    <name>A0A0S2DP36_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter, ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_4983</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949461.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4983"/>
    <dbReference type="EnsemblBacteria" id="ALN60324">
        <property type="protein sequence ID" value="ALN60324"/>
        <property type="gene ID" value="GLE_4983"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4983"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4910"/>
    <dbReference type="OMA" id="DPMTRLD"/>
    <dbReference type="OrthoDB" id="1303270at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="269"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="303"/>
            <end position="310"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="516" mass="55033" checksum="F02360B56ABBA52C" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPB5</accession>
    <name>A0A0S2DPB5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Hemagglutinin/YadA-like C-terminal region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLE_4980</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell surface</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4980"/>
    <dbReference type="EnsemblBacteria" id="ALN60321">
        <property type="protein sequence ID" value="ALN60321"/>
        <property type="gene ID" value="GLE_4980"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4980"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4907"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008640">
        <property type="entry name" value="Adhesin_Head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008635">
        <property type="entry name" value="Coiled_stalk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005594">
        <property type="entry name" value="YadA_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03895">
        <property type="entry name" value="YadA_anchor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05658">
        <property type="entry name" value="YadA_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05662">
        <property type="entry name" value="YadA_stalk"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101967">
        <property type="entry name" value="SSF101967"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="YadA_head" evidence="12">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="YadA_stalk" evidence="13">
        <location>
            <begin position="56"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="YadA_stalk" evidence="13">
        <location>
            <begin position="187"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="YadA_anchor" evidence="11">
        <location>
            <begin position="295"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="126"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF05662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN60321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="350" mass="34905" checksum="CA09EC55C273E3B9" modified="2016-02-17" version="1">MDATAIGNGNIASGARSLAAGFNAQATADDAVALGNNAVADRANTVSVGAAGAERQIVNVAAATQDTDAVNLSQLGRVMGVFGGGASFAGGVFAAPTFTVQGSAFNDVASAFGAVDGRLTDLYGRIANIPAGPQGPQGPQGPQGPQGPQGPQGPAGPGGSGGSPLSANYDDASRGTLTLEGANGTRVANVADATAATDAVNLRQMQAGDAAAVQQSNGYTNQQVQQANARADAGDARTLQSANSYTDQRINGLNLDFGNFRAEVNDRFEDLDRRIRRNGAMSAAMAQMSANSAYAKPGRGRLSVGAGFQDGESGLAIGYGRRINDNVSISIGAAFSGSESSGGVGFGVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPV0</accession>
    <name>A0A0S2DPV0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alpha-L-fucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_5068</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949528.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5068"/>
    <dbReference type="EnsemblBacteria" id="ALN60409">
        <property type="protein sequence ID" value="ALN60409"/>
        <property type="gene ID" value="GLE_5068"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5068"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4995"/>
    <dbReference type="OMA" id="LPEHKWE"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004560">
        <property type="term" value="F:alpha-L-fucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016286">
        <property type="entry name" value="FUC_metazoa-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000933">
        <property type="entry name" value="Glyco_hydro_29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10030">
        <property type="entry name" value="PTHR10030"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01120">
        <property type="entry name" value="Alpha_L_fucos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001092">
        <property type="entry name" value="Alpha-L-fucosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00741">
        <property type="entry name" value="GLHYDRLASE29"/>
    </dbReference>
    <dbReference type="SMART" id="SM00812">
        <property type="entry name" value="Alpha_L_fucos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595395" evidence="6">
        <location>
            <begin position="37"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="site" description="May be important for catalysis" evidence="5">
        <location>
            <position position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001092-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN60409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="495" mass="54672" checksum="60CD290C5DFBA573" modified="2016-02-17" version="1">MTPLHAAPFASRIVAAPLLAGLIAAGLAALAGAAHAATPAASVPKPAVAAPTESQAAFDARMRWWREARFGLFVHWGLYSGAAGRWNGEPVKGSAEWIQRNAHVPTDEYARQMLPLFEPKPGFAREWAKLAKQAGAKYLVFTSKHHEGFALHDSAVGDFDAKDATGRDLVREIVEAARAEGLKVGLYHSVIDWHHPAYPYRDFARLEHPLPHPLEKAGDAQDPDYAKRANLRQYQDFLHAQVRELVERYGPIDVLWWDYSNPGAEGETWRAQELMAMVRKDQPGIVMNNRLYRSLGYDDPQGSLQWFDRAHGDFTTPEQAIPARGVAGVDWEACMTMNGTWGYSALDTNWKSTRELLRDLVDTASKGGNLLLNIGPMADGSVPQASVDRLRQIGAWLRRNGESIYATNANPLGEVTWGRITAKRTAAGERLYLHVFERPSDGELRLRAPGRWTARLLDGGAALRVRRDGDDLAVAMPRTPADTIDTVIELVPAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPX5</accession>
    <name>A0A0S2DPX5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo/keto reductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Oxidoreductase, aldo/keto reductase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_00130</name>
        <name evidence="2" type="ORF">GLE_5369</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949754.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5369"/>
    <dbReference type="EnsemblBacteria" id="ALN60710">
        <property type="protein sequence ID" value="ALN60710"/>
        <property type="gene ID" value="GLE_5369"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5369"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5284"/>
    <dbReference type="OMA" id="HVDREGT"/>
    <dbReference type="OrthoDB" id="1351747at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="15"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="317" mass="33445" checksum="FD0C72A0CBD86F02" modified="2016-02-17" version="1">MNLRPLGRSSLSVAPLAFGGNVFGWSADEAASFALLDAFTEAGFALVDTADVYSAWVPGNQGGESERIIGRWLAQGGGRRERVVIATKVAKWAPRRGLAPANIQAAVEDSLRRLGTEVVDLYQAHEDDASVPLEDTLGAFARLIEQGKVRAIGASNYSAARLAQALDLSERLGLPRYETLQPQYNLYDRAGFEAELEPLARARGVGVIGYYSLASGFLTGKYRSRADLGKSRARAGAVENYLDARGLRILAALDEVAAGHGASPAQVALAWLIARPSVTAPIASATSVVQLQELLAAARLSLRADEIAALDAASAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQG7</accession>
    <name>A0A0S2DQG7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5398</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949778.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60739">
        <property type="protein sequence ID" value="ALN60739"/>
        <property type="gene ID" value="GLE_5398"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5398"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5313"/>
    <dbReference type="OrthoDB" id="1837969at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="230" mass="25103" checksum="0AA91E80823A1494" modified="2016-02-17" version="1">MDEPAPDADRGAAAALRLSGAVRRLQRTVQILSPRGRHGARVEFAVYRFELDRRRVALYVPLAPDGPAAAPLAEGDRVELLAQRYRHDARDDARQAEAGAVVALRNHDRGAAYACHSAFRWLMLDIAPVGYTPRMLRAALWWTLGLSLLACAAIPGFALAVGSSTPWQRTLADVAALVALIDAAIWLPVAALQLRWRLGRPTRRQRYTEQAYAALGFGSPLDPAPGLIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DRM0</accession>
    <name>A0A0S2DRM0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5499</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60840">
        <property type="protein sequence ID" value="ALN60840"/>
        <property type="gene ID" value="GLE_5499"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5499"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5414"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="64"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="129" mass="14339" checksum="C299E7B14109EE2C" modified="2016-02-17" version="1">MVAPLMKRIKTYKKELAALKAPARATRSTASKKASAKVALPSRVNHPAQISGEEAQAWYSTKNLIELREKFDLSAAGMADLVGVRPWSIYRWEAGEKPSVASMIKVASLRKISRTRALRMLEELRNSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-01-23" modified="2019-12-11" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A1EBU1</accession>
    <name>A1EBU1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_5109</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2006-11" db="EMBL/GenBank/DDBJ databases">
            <title>A type III secretion system from the microbial antagonist and biological control bacterium, Lysobacter enzymogenes strain C3.</title>
            <authorList>
                <person name="Reedy R.M."/>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">C3</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="EF119743">
        <property type="protein sequence ID" value="ABL59994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949561.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60450">
        <property type="protein sequence ID" value="ALN60450"/>
        <property type="gene ID" value="GLE_5109"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5109"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5034"/>
    <dbReference type="OrthoDB" id="1924665at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ABL59994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="138" mass="13898" checksum="600EC97C83AE75B8" modified="2007-01-23" version="1">MIEAIQVAAEAAQPAAASPAQSPQASAYDIREFAAAFDRGSAPGAAGGGQAGGVAQAGAAEPSQGTRAVLAALDNLNGGAESIGQASQSISANAAELTPGEMIQMTMKCHQFMFTSQLTSNVANRTSDGIQQLFRQQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAC2</accession>
    <name>A0A0S2DAC2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA polymerase sigma factor, ECF family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Sigma-70 family RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_05955</name>
        <name evidence="5" type="ORF">D9T17_02045</name>
        <name evidence="4" type="ORF">FE772_01615</name>
        <name evidence="2" type="ORF">GLE_0141</name>
    </gene>
    <organism evidence="2 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">C3</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 9" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000010">
        <property type="protein sequence ID" value="OPD65024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000006">
        <property type="protein sequence ID" value="ROU08892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945825.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0141"/>
    <dbReference type="EnsemblBacteria" id="ALN55500">
        <property type="protein sequence ID" value="ALN55500"/>
        <property type="gene ID" value="GLE_0141"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65024">
        <property type="protein sequence ID" value="OPD65024"/>
        <property type="gene ID" value="BV903_05955"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0141"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.143"/>
    <dbReference type="OMA" id="VVEMRYF"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011517">
        <property type="entry name" value="RNA_pol_sigma70_ECF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07638">
        <property type="entry name" value="Sigma70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02999">
        <property type="entry name" value="Sig-70_X6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD65024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU08892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="190" mass="21269" checksum="579864F509384305" modified="2016-02-17" version="1">MAESADITILLDAAREGDRGALDRVLATLYQELHTMARRQLAGQHGQTLDATALVHEAYLKLVGRREAQFDDRAHFFAYAASAMRSVVVDYARQRLAQKRGGDLHRVTELPDDVEGGLRLDEDTLGLDSALTKLAAVDQRLAQVVELRYFAGLSELEIAALLQRSERSIRRDWQKARLFLLASLQDEPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAD9</accession>
    <name>A0A0S2DAD9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sec-independent protein translocase protein TatA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">tatA</name>
        <name evidence="10" type="ORF">BV903_05870</name>
        <name evidence="12" type="ORF">D9T17_02110</name>
        <name evidence="11" type="ORF">FE772_01525</name>
        <name evidence="9" type="ORF">GLE_0122</name>
    </gene>
    <organism evidence="9 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 13">C3</strain>
        </source>
    </reference>
    <reference evidence="10 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">OH11</strain>
        </source>
    </reference>
    <reference evidence="11 16" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 16">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TatA/E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000010">
        <property type="protein sequence ID" value="OPD65008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000006">
        <property type="protein sequence ID" value="ROU08904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945811.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000006.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55481">
        <property type="protein sequence ID" value="ALN55481"/>
        <property type="gene ID" value="GLE_0122"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65008">
        <property type="protein sequence ID" value="OPD65008"/>
        <property type="gene ID" value="BV903_05870"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0122"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.125"/>
    <dbReference type="OMA" id="GGISIWN"/>
    <dbReference type="OrthoDB" id="1907955at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033281">
        <property type="term" value="C:TAT protein transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00236">
        <property type="entry name" value="TatA_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003369">
        <property type="entry name" value="TatA/B/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006312">
        <property type="entry name" value="TatA/E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02416">
        <property type="entry name" value="TatA_B_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01411">
        <property type="entry name" value="tatAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="40"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="40"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN55481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD65008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW24549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROU08904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="76" mass="8328" checksum="2B64845C6728DA77" modified="2016-02-17" version="1">MGAWGIGHWIIVLVIVLLVFGTKRLGSVGKDLGDAVKGFKKGMADDEDKQPGQLKDETRNSSDSNTSARNDERNQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAL0</accession>
    <name>A0A0S2DAL0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mg chelatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0236</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945891.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0236"/>
    <dbReference type="EnsemblBacteria" id="ALN55595">
        <property type="protein sequence ID" value="ALN55595"/>
        <property type="gene ID" value="GLE_0236"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0236"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.238"/>
    <dbReference type="OMA" id="STNPCPC"/>
    <dbReference type="OrthoDB" id="581802at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032508">
        <property type="term" value="P:DNA duplex unwinding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045006">
        <property type="entry name" value="CHLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004482">
        <property type="entry name" value="Mg_chelat-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025158">
        <property type="entry name" value="Mg_chelat-rel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000523">
        <property type="entry name" value="Mg_chelatse_chII-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039">
        <property type="entry name" value="PTHR32039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039:SF7">
        <property type="entry name" value="PTHR32039:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01078">
        <property type="entry name" value="Mg_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13335">
        <property type="entry name" value="Mg_chelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00368">
        <property type="entry name" value="TIGR00368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM" evidence="2">
        <location>
            <begin position="291"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="508" mass="54020" checksum="1DCDDF68334D7518" modified="2016-02-17" version="1">MNLALVHSRARTGVRAPAVRVEVHLGGGLPCMNIVGLPEAAVREAKDRVRAAIASAQYEFPQRRITVNLAPADLPKDGGRYDLAIALGILAASGQLPLPALADCEFLGELGLTGELRAIDGVLPAALAAAEAGRRLVVPAGNGAEAALASRVEARTARTLSEVCAMLCERAPLPRAVAPPLARAPELDMRDVRGQAQARRALEIAAAGGHHLLLIGPPGCGKTLLASRLPGLLPEASEDEALETAAIASVGGGGHGRALDPSRWRQRPFRAPHHTASAVALVGGGADPRPGEISLAHQGVLFLDELPEWERRALEVLREPLESGAVTVSRAARSAEFPARFQLVAAMNPCPCGWAGDSSARCRCTQDIIRRYRARISGPLLDRIDLHIEVPRLPPAALRPDQPEGECSAAIRERVTAARQRQAERSGRTNSRLDQAQTNQHCRLGERDQALLERAVDGLQLSARSMHRILRVARTIADLADSANIGTAHLTEAIGYRRADRDSAARAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAL1</accession>
    <name>A0A0S2DAL1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Formylglycine-generating enzyme family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_01825</name>
        <name evidence="3" type="ORF">GLE_0191</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945862.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0191"/>
    <dbReference type="EnsemblBacteria" id="ALN55550">
        <property type="protein sequence ID" value="ALN55550"/>
        <property type="gene ID" value="GLE_0191"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0191"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.193"/>
    <dbReference type="OMA" id="EWEWQYA"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
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        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FGE-sulfatase" evidence="2">
        <location>
            <begin position="483"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="727" mass="83006" checksum="15E1EF9782A6F4A6" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAR2</accession>
    <name>A0A0S2DAR2_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_01545</name>
        <name evidence="2" type="ORF">GLE_0126</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0126"/>
    <dbReference type="EnsemblBacteria" id="ALN55485">
        <property type="protein sequence ID" value="ALN55485"/>
        <property type="gene ID" value="GLE_0126"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0126"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.129"/>
    <dbReference type="OMA" id="ISCIPKP"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="256"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="310" mass="33369" checksum="B1881555EF2DC431" modified="2016-02-17" version="1">MTPSIRKVPLTHGAQWLLRAINLGTRNPRAIFGAALLLIAVLYLVMYVFTMPLRLGGEPDLEGLFRILAIAMLAAALVLPVLLGGLMHVIREAENGRPVRARDLFAPLRLQRTLPLALLGLIQIALALICGSLLLWATGEDFWAQYQEMVRGAITGRISTVPTAEQPALVALAQLLFYYFSTAVVLVSVPQIMFSGLGLSDAVKRSFGASLWNLGSYLFATMLFMLGAMLAGLLVSVAALVVMVLGASVTPMLGHLLAWVLFTAYGMAFLVVMCGTCYYAWRDVFAQDGDGAAAGGATPQPPARQDRFEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB62</accession>
    <name>A0A0S2DB62_LYSEN</name>
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        <recommendedName>
            <fullName evidence="2">DUF2007 domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="3" type="ORF">GLE_0337</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945963.1">
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_0337"/>
    <dbReference type="EnsemblBacteria" id="ALN55695">
        <property type="protein sequence ID" value="ALN55695"/>
        <property type="gene ID" value="GLE_0337"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0337"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.334"/>
    <dbReference type="OMA" id="VIRRWEA"/>
    <dbReference type="OrthoDB" id="1604938at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018551">
        <property type="entry name" value="DUF2007"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09413">
        <property type="entry name" value="DUF2007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2007" evidence="2">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="288" mass="31638" checksum="20B66F42EA189760" modified="2016-02-17" version="1">MQTVHHAADPADAQRVRDALEREGIRVFVSRDAPQAGAGPLPPGGPARVDVADEDAARARAIVQAWQAAEAPRGDNDAPAHDHDGDPDDAANARAPGRNGFGRGELVFALIAGAALGALVAATALHPHEARQDEVRQDVDYDRDGVADERAVYRGQRLLRMESDRNSDGRVDAVTYFDANGLPTSGEEDQDFDGVRETRARYDQRLPILYSADYDGDGVPEWRQNFRRGVVQNLEWLDRQGRVVKRDEYVGGRLRRGQIDRDGDGKLDTARVYDDRGEVLSSEPLPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBQ8</accession>
    <name>A0A0S2DBQ8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase, group 1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0588</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0588"/>
    <dbReference type="EnsemblBacteria" id="ALN55946">
        <property type="protein sequence ID" value="ALN55946"/>
        <property type="gene ID" value="GLE_0588"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0588"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.581"/>
    <dbReference type="OMA" id="MERLNWH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
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        <location>
            <begin position="92"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="404" mass="44557" checksum="A91EF2FE6721BAAF" modified="2016-02-17" version="1">MARDARDGSGHRKDLRSERADRSDAQADDSHSNGAHSNGAHARDPFPDRSAHAADARSIWYLTRKFPPSRGGMQQLSARIAGELSALRPLTLVRWGRGQWGLPLFLPWALARLLVGLLRGRVRVLLLGDPVLAALALPARWAGVPVAVVVHGLDIDWPHRGYRAYLRRFFWNRCDVYFCISRYVRDRLGEGGVDPARCALVHPGVAATAPSPRVPPAAEPRLLILGRLVRRKGALWFVEHVMPKLRADPRGIVLDIVGEGPDRAAIERAIEREGLHARVRLWGEVDDAEKARRLDACDLALMPNRRVPGDPEGFGLVALEAAMSGRYVLAADLEGLRDALADPALGRLLPERADPDLWSAAILELLADRAALRERGRAARAHAAAHCTWRGMAQRYAERLDAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBT8</accession>
    <name>A0A0S2DBT8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BV903_08170</name>
        <name evidence="6" type="ORF">GLE_0631</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000017">
        <property type="protein sequence ID" value="OPD64391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946175.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000017.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0631"/>
    <dbReference type="EnsemblBacteria" id="ALN55989">
        <property type="protein sequence ID" value="ALN55989"/>
        <property type="gene ID" value="GLE_0631"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64391">
        <property type="protein sequence ID" value="OPD64391"/>
        <property type="gene ID" value="BV903_08170"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0631"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.621"/>
    <dbReference type="OMA" id="VWGWDFG"/>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="15"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="138"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="138"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN55989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD64391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="243" mass="25763" checksum="76F20E457C7047FF" modified="2016-02-17" version="1">MPPKSSDAVAAAQPRLLLVDDDADILALLVRYLGANGCKTATAASAAQARATVAAGGIDLVLLDLGLPDEDGLSLLRHLQTQWRGPVIVVSGRGEAVDRVVGLELGADDYVAKPFDLRELLARVRSVLRRAAAPAPAAECLAFEGFRLDLSARRLTDATGTEIALTTGEFQLLRALLQRPQQVLSRDELMTALHGREAGPYDRTIDVAIGRLRRKIEADPAAPGLIKAVRGAGYLFAAAVSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBV0</accession>
    <name>A0A0S2DBV0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_03810</name>
        <name evidence="1" type="ORF">GLE_0620</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946168.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55978">
        <property type="protein sequence ID" value="ALN55978"/>
        <property type="gene ID" value="GLE_0620"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0620"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.612"/>
    <dbReference type="OrthoDB" id="2038023at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="107" mass="11511" checksum="3BB5D33659EAF668" modified="2016-02-17" version="1">MDTHSPLHELPPGFHWEAPFAGSIFPSHLVAVPDEDCEAWLATVTPARDGHGAIATIRRHLGLKDHVSRPFRTDAAAAGWVARWLSGQGEAVRAELAVDWSAAARAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBX0</accession>
    <name>A0A0S2DBX0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribosomal RNA small subunit methyltransferase C</fullName>
            <ecNumber evidence="2">2.1.1.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rsmC</name>
        <name evidence="2" type="ORF">GLE_0660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.5" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0660"/>
    <dbReference type="EnsemblBacteria" id="ALN56018">
        <property type="protein sequence ID" value="ALN56018"/>
        <property type="gene ID" value="GLE_0660"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0660"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.649"/>
    <dbReference type="OMA" id="RHCQLWQ"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047150">
        <property type="term" value="F:betaine-homocysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044260">
        <property type="term" value="P:cellular macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043412">
        <property type="term" value="P:macromolecule modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTS" evidence="1">
        <location>
            <begin position="175"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="350" mass="38183" checksum="D8898EB6FB7AB9DF" modified="2016-02-17" version="1">MRVDRSDDALDTLFQPFADGVLAWPGEALFLRARDGVGLRQAPRPGLLCEQDFKPAADALERGGLDAIELESLDPQRRFPLVLVLPPRQREEARALFAQAVARCAPGGRVLACMRNDEGARSGEDDLAKLAGKVGSLSKRKCRAFWSAPLQGPADPALVRAWSALDAPRDILGGRFRSRPGVFAWDRIDPASALLAAHLPADLAGRAADLGAGYGYLAAELLARCPRIASLDLYEAQARAVALARHNLDGARVPVESFWHDVTAGLPRRYDVIVSNPPFHAQGREERPDIGRRFIEVAAQSLERGGRFWMVANRHLPYEHALGEHFSEVRTVAQDGGFKVVEARGARGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC47</accession>
    <name>A0A0S2DC47_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF2752 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_22535</name>
        <name evidence="4" type="ORF">FE772_04360</name>
        <name evidence="2" type="ORF">GLE_0734</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000075">
        <property type="protein sequence ID" value="OPD61675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946258.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000075.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0734"/>
    <dbReference type="EnsemblBacteria" id="ALN56092">
        <property type="protein sequence ID" value="ALN56092"/>
        <property type="gene ID" value="GLE_0734"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61675">
        <property type="protein sequence ID" value="OPD61675"/>
        <property type="gene ID" value="BV903_22535"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0734"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.722"/>
    <dbReference type="OMA" id="GAMAMNP"/>
    <dbReference type="OrthoDB" id="1911879at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021215">
        <property type="entry name" value="DUF2752"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10825">
        <property type="entry name" value="DUF2752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="139" mass="14685" checksum="FFB316C0D7B89DC4" modified="2016-02-17" version="1">MQAPARHYALAATVAAAGAVAAAGAWVLRRVDPNAAGSPLPGCMFYHFTGLYCPGCGMTRAAHALVHGDLAQAVAMNPLLPLLLLTLPLLALHSLGYRLPVPQRAIAALTSAKFWLPLLGGFWVLRNLPWPPFSWLAPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC59</accession>
    <name>A0A0S2DC59_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_22490</name>
        <name evidence="3" type="ORF">GLE_0725</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000075">
        <property type="protein sequence ID" value="OPD61670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946251.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0725"/>
    <dbReference type="EnsemblBacteria" id="ALN56083">
        <property type="protein sequence ID" value="ALN56083"/>
        <property type="gene ID" value="GLE_0725"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61670">
        <property type="protein sequence ID" value="OPD61670"/>
        <property type="gene ID" value="BV903_22490"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0725"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.713"/>
    <dbReference type="OMA" id="GLNTHSI"/>
    <dbReference type="OrthoDB" id="970661at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="49"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD61670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="245" mass="27388" checksum="7E76819C073FC39F" modified="2016-02-17" version="1">MSKTPPPRFVIVQQQPDKRPYIWSAVGVAWAVSLALAWWWSQSLAAPQLPKLKVELDQTRRELRQRQSELDKLAQREANLQRSDQISRAANKQVQSSLAQREEEISDLRADVAFYERLVGATAPAKGLNVHSVEFHAEAGGTWRYQIVLTQNLNRGAVSSGGLQFQVEGVRGGKLASVGWDELHQKSKAPAQDYSFRYFQTLDGSVMLPAGFTPQRIRVSLRGENAAIEQRFAWKSGVTVTTGET</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCC3</accession>
    <name>A0A0S2DCC3_LYSEN</name>
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        <submittedName>
            <fullName evidence="7">Transporter, major intrinsic protein (MIP) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_0813</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0813"/>
    <dbReference type="EnsemblBacteria" id="ALN56171">
        <property type="protein sequence ID" value="ALN56171"/>
        <property type="gene ID" value="GLE_0813"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0813"/>
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    <dbReference type="OMA" id="ACFPGRK"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015267">
        <property type="term" value="F:channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="SSF81338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN56171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="239" mass="24108" checksum="DF32CA00A5E19B94" modified="2016-02-17" version="1">MATPMAQYLSEFIATAMLILLGNGVVAGALLNKSKAQGAGWGVITAAWGLAVLIGICIAGPTSGAIMNPALTIGLAAIGKLAWALVPGFVIAQIAGAFAGATLVWLTYLAHWRVSDDPELKRAIFCTSPAIRDTKANVLTEVIGTFALTFGALAIGANSFAPGMGPLGVGLLVVVIGMSLGGPTGYAINPARDLGPRLAHALLPIAGKGGSDWGYAWVPVVAPIVGAVLGAFAFQAVYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCG8</accession>
    <name>A0A0S2DCG8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TetR/AcrR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_04715</name>
        <name evidence="4" type="ORF">GLE_0809</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946313.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56167">
        <property type="protein sequence ID" value="ALN56167"/>
        <property type="gene ID" value="GLE_0809"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0809"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.798"/>
    <dbReference type="OMA" id="AAEHFFC"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039536">
        <property type="entry name" value="TetR_C_Proteobacteria"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14246">
        <property type="entry name" value="TetR_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="31"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="227" mass="24628" checksum="4BF1D53A95D863FA" modified="2016-02-17" version="1">MVSPRPSSQTDAAGQKASAAKPAGPGRPKDLSKRNAILEAAKRLFLIEGYDGVSMDQIAAEAGVSKLTVYSHFGDKETLFAAAVRAHCEQHLPALLFAPEPGTPLRERLLAIAQAFFEMASAPEAIRIHRLLCTPQLAQSPLTRLFWDVGPHRLHEEFAGLLRSRAEAGELDLADADTAARQFFAVLKGEPYALLMLGYPLPGKAETRAHLEASVDMFLRAYARRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCL0</accession>
    <name>A0A0S2DCL0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CD225/dispanin family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_22540</name>
        <name evidence="4" type="ORF">FE772_04365</name>
        <name evidence="2" type="ORF">GLE_0735</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000075">
        <property type="protein sequence ID" value="OPD61676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946259.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000075.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0735"/>
    <dbReference type="EnsemblBacteria" id="ALN56093">
        <property type="protein sequence ID" value="ALN56093"/>
        <property type="gene ID" value="GLE_0735"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61676">
        <property type="protein sequence ID" value="OPD61676"/>
        <property type="gene ID" value="BV903_22540"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0735"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.723"/>
    <dbReference type="OrthoDB" id="2046989at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007593">
        <property type="entry name" value="CD225/Dispanin_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04505">
        <property type="entry name" value="CD225"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="110" mass="11653" checksum="4010E5EB780FF5C8" modified="2016-02-17" version="1">MNQPVVAGSPYPNYLVWSIIVTVLGACFCCLIGAAPGVVAIVFGSQVGSKLAAGDEAGARRASEQAKLWCWIGTALVAVGVLWTILSFFIEGASFMSQEFLEQVRQAQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCL4</accession>
    <name>A0A0S2DCL4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Heme chaperone HemW</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">hemN</name>
        <name evidence="13" type="synonym">hemW</name>
        <name evidence="13" type="ORF">FE772_05175</name>
        <name evidence="12" type="ORF">GLE_0904</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">C3</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0904"/>
    <dbReference type="EnsemblBacteria" id="ALN56262">
        <property type="protein sequence ID" value="ALN56262"/>
        <property type="gene ID" value="GLE_0904"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0904"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.892"/>
    <dbReference type="OMA" id="HIPWCVR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034505">
        <property type="entry name" value="Coproporphyrinogen-III_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010723">
        <property type="entry name" value="HemN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004559">
        <property type="entry name" value="HemW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932">
        <property type="entry name" value="PTHR13932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06969">
        <property type="entry name" value="HemN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00562">
        <property type="entry name" value="HemN-like__clustered_with_heat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00539">
        <property type="entry name" value="hemN_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9 10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="11">
        <location>
            <begin position="4"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN56262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW25146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="400" mass="43838" checksum="E1D7C1F9FBE07C73" modified="2016-02-17" version="1">MSVALVPPPLSLYVHLPWCVRKCPYCDFNSHEARGAPPFAAYVDALVADLEHDLPLVWGRTVHSVFFGGGTPSLFPPEAIDRFLQAASARLRFAPGCEITLETNPGTAEHGRFELYKAAGVNRLSFGIQSFDDGCLQRLGRIHGSAEAEAAVKLARDAGFDNFNLDLMYALPGQTLAMAEYDLERAFALEPAHISHYQLTLEPNTVFAARPPQDIPDEDNAWDIQERCQALLAQRGYGQYEVSAYARPGRQCKHNLNYWRYGDYLGIGAGAHGKISLGAEQAIARRWKLKHPTAYLAQAGTAAAIGGDERIAPARRPFEYMLNALRLVEGFSLDSFEASTGLGRDAIAAQLAEAMAAGWLERDGDRVRPTELGRRFTNDVVALFLDEDAATDDTGAARLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCL6</accession>
    <name>A0A0S2DCL6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4166 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_05265</name>
        <name evidence="2" type="ORF">GLE_0923</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946398.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56281">
        <property type="protein sequence ID" value="ALN56281"/>
        <property type="gene ID" value="GLE_0923"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0923"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.911"/>
    <dbReference type="OMA" id="AWCIRTP"/>
    <dbReference type="OrthoDB" id="1712325at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025311">
        <property type="entry name" value="DUF4166"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13761">
        <property type="entry name" value="DUF4166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4166" evidence="1">
        <location>
            <begin position="20"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="215" mass="23890" checksum="170F92AD746188D8" modified="2016-02-17" version="1">MPGEPHNAAIGWFGPAFDRLHPLLQALHRDGGALAGEIELRSGRGLAGVLGRRLARRLGIPLDRPRRGFRVDIVHEPARMLWLRRFDDGSELRSVFEPVGHWPDGHWLETTGPVRLRLGVDLDGGGWRWRLLGLSARGLPLPRLLFPRTDASKRIERIDDEERYRFAVVFSWFPFGELLRYQGALHAVPAVTAPSAVPAGAANVAAHCSAQRVTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCM8</accession>
    <name>A0A0S2DCM8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Oxidoreductase, short chain dehydrogenase/reductase family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_05155</name>
        <name evidence="1" type="ORF">GLE_0898</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946378.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56256">
        <property type="protein sequence ID" value="ALN56256"/>
        <property type="gene ID" value="GLE_0898"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0898"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.887"/>
    <dbReference type="OMA" id="RDKLMGQ"/>
    <dbReference type="OrthoDB" id="1356861at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="198" mass="20534" checksum="703EE183EF7BEF0E" modified="2016-02-17" version="1">MKILLVGGSGTLGRAIAQTLSHHEILAAGRSSAQYPVDITDDASVEALLRKTGKLDAIVSAAGALHFGPLSEMKPADFAIGLNDKLLGQVRLALLGQHHLFDGGSITLTTGIVSAEPIRAGANASAVNRAIEGFVAGAACELPRGLRINAVSPSVLSESMDAYGAFFPGFEPVPAARAALAYRRSVEGVQSGRTFEVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCN1</accession>
    <name>A0A0S2DCN1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Penicillin-binding protein 1A</fullName>
            <ecNumber evidence="8">2.4.1.129</ecNumber>
            <ecNumber evidence="7">3.4.16.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="primary">mrcA</name>
        <name evidence="24" type="ORF">FE772_05295</name>
        <name evidence="23" type="ORF">GLE_0931</name>
    </gene>
    <organism evidence="23 25">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="23 25" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 25">C3</strain>
        </source>
    </reference>
    <reference evidence="24 26" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24 26">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the C-terminal section; belongs to the transpeptidase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">In the N-terminal section; belongs to the glycosyltransferase 51 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.129" evidence="8"/>
    <dbReference type="EC" id="3.4.16.4" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946403.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0931"/>
    <dbReference type="EnsemblBacteria" id="ALN56289">
        <property type="protein sequence ID" value="ALN56289"/>
        <property type="gene ID" value="GLE_0931"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0931"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.919"/>
    <dbReference type="OMA" id="LAQMAMI"/>
    <dbReference type="OrthoDB" id="652304at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001264">
        <property type="entry name" value="Glyco_trans_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036950">
        <property type="entry name" value="PBP_transglycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031376">
        <property type="entry name" value="PCB_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17092">
        <property type="entry name" value="PCB_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00912">
        <property type="entry name" value="Transgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="10" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="12 23" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13 23" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="19" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="11" id="KW-0645">Protease</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="23" id="KW-0808">Transferase</keyword>
    <keyword evidence="19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="Transgly" evidence="21">
        <location>
            <begin position="59"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="PCB_OB" evidence="22">
        <location>
            <begin position="321"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="20">
        <location>
            <begin position="444"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="408"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="656"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="662"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00007739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00012555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00018638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF17092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="ALN56289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="QCW25167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="855" mass="93431" checksum="4E23B314AF5795F5" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD53</accession>
    <name>A0A0S2DD53_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 9 12">Homoserine dehydrogenase</fullName>
            <shortName evidence="9">HDH</shortName>
            <ecNumber evidence="5 9 12">1.1.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">FE772_06160</name>
        <name evidence="16" type="ORF">GLE_1124</name>
    </gene>
    <organism evidence="16 18">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="16 18" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">C3</strain>
        </source>
    </reference>
    <reference evidence="17 19" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-homoserine + NAD(+) = H(+) + L-aspartate 4-semialdehyde + NADH</text>
            <dbReference type="Rhea" id="RHEA:15757"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.1.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9 12">
            <text>L-homoserine + NADP(+) = H(+) + L-aspartate 4-semialdehyde + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15761"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.1.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 12">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 3/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9 13">Belongs to the homoserine dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.3" evidence="5 9 12"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1124"/>
    <dbReference type="EnsemblBacteria" id="ALN56482">
        <property type="protein sequence ID" value="ALN56482"/>
        <property type="gene ID" value="GLE_1124"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1124"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1110"/>
    <dbReference type="OMA" id="YNDDYSP"/>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00063"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004412">
        <property type="term" value="F:homoserine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005106">
        <property type="entry name" value="Asp/hSer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001342">
        <property type="entry name" value="HDH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019811">
        <property type="entry name" value="HDH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022697">
        <property type="entry name" value="HDH_short"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00742">
        <property type="entry name" value="Homoserine_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03447">
        <property type="entry name" value="NAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036497">
        <property type="entry name" value="HDH_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01042">
        <property type="entry name" value="HOMOSER_DHGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 12" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="9 12" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="9 12" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="7 9 11" id="KW-0521">NADP</keyword>
    <keyword evidence="8 9 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="NAD_binding_3" evidence="15">
        <location>
            <begin position="38"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Homoserine_dh" evidence="14">
        <location>
            <begin position="177"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="38"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR036497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR036497-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR036497-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF03447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ALN56482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="QCW25306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="381" mass="38947" checksum="C6C7C21BD0A71596" modified="2016-02-17" version="1">MSAVAASALHGAEALAQAPALRPSPTVGAAPARVALLGTGTVGGAVLARLGGWRGGPLDGRLRLVHVANSRRAAADADGIVPEHAASALAAADQRSSLDDVADALAGGSGARVVIDATASEAVAERHAQWLAQGIHVVTACKIGQGTTLARWRAIREACASGGAGYGDSATVGAGLPLLRSLRELQAGGDRIHAVAGVLSGSLAWLFNHYDGMRPFSALVRQARDAGYTEPDPRDDLSGEDVRRKLLILARAAGVALEAGEVEVASLVPPELAILSREGVDAALPALDAPLRERYAQAYKNGERLRFIARLERAADGRVVAQVGLQSLPGDHPLAGGAGTDNKVAIWSDRYRAQPLAIQGPGAGAEVTAAGLLDDVLRLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDC3</accession>
    <name>A0A0S2DDC3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2-hydroxychromene-2-carboxylate isomerase</fullName>
            <ecNumber evidence="1">5.99.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">nahD</name>
        <name evidence="4" type="ORF">GLE_1073</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-hydroxychromene-2-carboxylate = (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate</text>
            <dbReference type="Rhea" id="RHEA:27401"/>
            <dbReference type="ChEBI" id="CHEBI:59350"/>
            <dbReference type="ChEBI" id="CHEBI:59353"/>
            <dbReference type="EC" id="5.99.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily. NadH family.</text>
    </comment>
    <dbReference type="EC" id="5.99.1.4" evidence="1"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946505.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1073"/>
    <dbReference type="EnsemblBacteria" id="ALN56431">
        <property type="protein sequence ID" value="ALN56431"/>
        <property type="gene ID" value="GLE_1073"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1073"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1061"/>
    <dbReference type="OMA" id="FGAPWYV"/>
    <dbReference type="OrthoDB" id="996965at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018845">
        <property type="term" value="F:2-hydroxychromene-2-carboxylate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901170">
        <property type="term" value="P:naphthalene catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03022">
        <property type="entry name" value="DsbA_HCCA_Iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001853">
        <property type="entry name" value="DSBA-like_thioredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014440">
        <property type="entry name" value="HCCAis_GSTk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044087">
        <property type="entry name" value="NahD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01323">
        <property type="entry name" value="DSBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006386">
        <property type="entry name" value="HCCAis_GSTk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DSBA" evidence="3">
        <location>
            <begin position="5"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006386-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="212" mass="22872" checksum="82593347B2096F5C" modified="2016-02-17" version="1">MSVAVDYYFSLISPYAYLGHAPLLALARETGAHLRYKPVRIFELFSANGGLPLGQRAPARQRYRVVELQRARAERDVPLNLTPKHFPVDPGLADRCAIALMRAGRDPAQYMDTVFRAIWAHDEDIADRGVLARALRDAGHDADAILAAADTGAVAEVYQDNTAAAIANDLPGLPGYVLNGEPFWGQDRVDALRAALVSGRAPFLAGAGAAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDJ4</accession>
    <name>A0A0S2DDJ4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">M20/M25/M40 family metallo-hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Peptidase family M20/M25/M40</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_06705</name>
        <name evidence="3" type="ORF">GLE_1240</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057950003.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1240"/>
    <dbReference type="EnsemblBacteria" id="ALN56597">
        <property type="protein sequence ID" value="ALN56597"/>
        <property type="gene ID" value="GLE_1240"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1240"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1224"/>
    <dbReference type="OMA" id="EWDASII"/>
    <dbReference type="OrthoDB" id="275025at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="2">
        <location>
            <begin position="218"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="508" mass="55010" checksum="35B638188B141626" modified="2016-02-17" version="1">MDASKVDRYVGQKWDDEIVPQLVEYIRIPNKSPMFDADWVKHGYMDDAVKLMESWAKAQSIPGMQVEVVRLEGRTPLIFIDIPAFDGATARAAADAPAQRDEDCVLLYGHLDKQPEMTGWDDDLGPWKPVIKGDKLFGRGGADDGYAIFGSLAAILALQDQQVPHSRCVILIEACEESGSYDLPAYVDHLAERIGKPSLVVCLDSGCGNYDQLWCTTSLRGLAGGNFTVKVLSEGVHSGDASGVVPSSFRLLRQLLSRLEDETSGKILVEGLYVEVPEERMEQARQAAKVLDTAVYDKFPFLPGMKPMADELSELVLNRTWRPALSVTGVDGMPSLASAGNVLRPYTSVKLSLRLPPTLDGKRAGELLKEVLLRDPPNGAQVSLELEKSSSGWNAPAMSSWLSKAIDASSREFFGQPAMYMGEGGSIPFMGMLGEKFPGAQFMITGVLGPHSNAHGPNEFLHIPMGKRVTACVARVVAEHHQASQRGETTGAAVVADSGDRHGGHGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDK9</accession>
    <name>A0A0S2DDK9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_24520</name>
        <name evidence="4" type="ORF">FE772_07095</name>
        <name evidence="2" type="ORF">GLE_1326</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000095">
        <property type="protein sequence ID" value="OPD61287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946691.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000095.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56683">
        <property type="protein sequence ID" value="ALN56683"/>
        <property type="gene ID" value="GLE_1326"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61287">
        <property type="protein sequence ID" value="OPD61287"/>
        <property type="gene ID" value="BV903_24520"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1326"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1310"/>
    <dbReference type="OrthoDB" id="2025474at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046256">
        <property type="entry name" value="DUF6289"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19806">
        <property type="entry name" value="DUF6289"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594862" evidence="1">
        <location>
            <begin position="23"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="77" mass="8028" checksum="E563AC21CD4FE4DF" modified="2016-02-17" version="1">MRKSFALGLGLSAALVATAALARPPGPDEIGEFYFYFDAAGNVVGQAELSCSGVYTESGVRTAKYSSGHMVCPPPRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDM2</accession>
    <name>A0A0S2DDM2_LYSEN</name>
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        <submittedName>
            <fullName evidence="4">FAD dependent oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">NADPH-dependent 2,4-dienoyl-CoA reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_06960</name>
        <name evidence="4" type="ORF">GLE_1293</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
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        <property type="protein sequence ID" value="ALN56650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW25444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946666.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1293"/>
    <dbReference type="EnsemblBacteria" id="ALN56650">
        <property type="protein sequence ID" value="ALN56650"/>
        <property type="gene ID" value="GLE_1293"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1293"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1276"/>
    <dbReference type="OMA" id="GWVHRAH"/>
    <dbReference type="OrthoDB" id="1308229at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_FMN" evidence="2">
        <location>
            <begin position="30"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_2" evidence="3">
        <location>
            <begin position="399"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="701" mass="75000" checksum="83EEB80FB88FA8B4" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDS1</accession>
    <name>A0A0S2DDS1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56608">
        <property type="protein sequence ID" value="ALN56608"/>
        <property type="gene ID" value="GLE_1251"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1251"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1235"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="179" mass="20241" checksum="D8B82F841D3E8983" modified="2016-02-17" version="1">MASCKTIEPANGTLQDMQEWATPEPLDRLSSANEQRRAKAAMVRWVERYLKREYRVIGRRFVLTAPGSTDGAAIGSKAHQFATQNLGGTMLIDGWYDDDDYRFFLWTFGDGSRRYVAFVLTGGFLPGTDERRMVGYLELVRYAKERTKTAQEGSAAKARQYKVAESNEADDHLDVVDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDV2</accession>
    <name>A0A0S2DDV2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TfoX-like protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">TfoX/Sxy family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_07440</name>
        <name evidence="3" type="ORF">GLE_1407</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946753.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1407"/>
    <dbReference type="EnsemblBacteria" id="ALN56764">
        <property type="protein sequence ID" value="ALN56764"/>
        <property type="gene ID" value="GLE_1407"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1407"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1387"/>
    <dbReference type="OMA" id="DLMAKWV"/>
    <dbReference type="OrthoDB" id="2040341at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007076">
        <property type="entry name" value="TfoX_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04993">
        <property type="entry name" value="TfoX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TfoX_N" evidence="2">
        <location>
            <begin position="13"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="128" mass="14405" checksum="8AD08FE4C598535A" modified="2016-02-17" version="1">MHEDLIAHLHDLSAGFGALDARRMFGGHGVYRDGTMIGLLSDETLYLKTDEHTLPRFRAAGCSPFLYARRGETVPTSYWTVPEQAMESPQDMRPWLALAWEAAVRKAAKKRPVKKRAAKKVAKKKPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE46</accession>
    <name>A0A0S2DE46_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase_M4_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1466</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1466"/>
    <dbReference type="EnsemblBacteria" id="ALN56823">
        <property type="protein sequence ID" value="ALN56823"/>
        <property type="gene ID" value="GLE_1466"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1466"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1447"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001570">
        <property type="entry name" value="Peptidase_M4_C_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02868">
        <property type="entry name" value="Peptidase_M4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M4_C" evidence="2">
        <location>
            <begin position="10"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="124" mass="13195" checksum="A321BC7865468BF6" modified="2016-02-17" version="1">MARSGDTAIVGIGIGKAKLDAIRYRALTQYFVSSAGYPSARAGTLQAAADLYGNGSVEYQTAARAWPALKADRSIAASRRARGTRAGPAPAGRSRSRATLPRRRVRIITKPRYVTRSESACAIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEB9</accession>
    <name>A0A0S2DEB9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56987">
        <property type="protein sequence ID" value="ALN56987"/>
        <property type="gene ID" value="GLE_1630"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1630"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="53" mass="5406" checksum="1BCD5AFBB9ACF1FB" modified="2016-02-17" version="1">MVAGSHRGGGGAIGGRRNAAGGDEAALARDGTGRVFPLRNPHPRHSGESRNPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEI8</accession>
    <name>A0A0S2DEI8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Methyltransferase domain family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1583</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946896.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56940">
        <property type="protein sequence ID" value="ALN56940"/>
        <property type="gene ID" value="GLE_1583"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1583"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1563"/>
    <dbReference type="OMA" id="GDYQDGW"/>
    <dbReference type="OrthoDB" id="1515497at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="232" mass="25008" checksum="172CFEDD17E5BD37" modified="2016-02-17" version="1">MSADDVRHSDARVLAAWRENAAPWTRSVRTQAIESRRLVTDRAVVEAATRLRPRSALDLGCGEGWLTRALLAHGIDARGSDAVPALIEAARRADPAAPPQRYACLSYEDIAAGAFDARFDLIVCNFSLLGGAAIDALLVALPAHLNEGGHVLIQTLHPPTANADAPYRDGWRDGSWAGCEGDFGEPAPWYFRTLGGWLAVLQRSGLTLRALEEPLHPQTQRPASLILLAAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEI9</accession>
    <name>A0A0S2DEI9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="12">DNA-3-methyladenine glycosylase II</fullName>
            <ecNumber evidence="12">3.2.2.21</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">alkA</name>
        <name evidence="12" type="ORF">GLE_1362</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alkylbase DNA glycosidase AlkA family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.21" evidence="12"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1362"/>
    <dbReference type="EnsemblBacteria" id="ALN56719">
        <property type="protein sequence ID" value="ALN56719"/>
        <property type="gene ID" value="GLE_1362"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1362"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1344"/>
    <dbReference type="OMA" id="RWPDAFP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008725">
        <property type="term" value="F:DNA-3-methyladenine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052822">
        <property type="term" value="F:DNA-3-methylguanine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052821">
        <property type="term" value="F:DNA-7-methyladenine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043916">
        <property type="term" value="F:DNA-7-methylguanine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035451">
        <property type="entry name" value="Ada-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004026">
        <property type="entry name" value="Ada_DNA_repair_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010316">
        <property type="entry name" value="AlkA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037046">
        <property type="entry name" value="AlkA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000035">
        <property type="entry name" value="Alkylbase_DNA_glycsylse_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02805">
        <property type="entry name" value="Ada_Zn_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06029">
        <property type="entry name" value="AlkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01009">
        <property type="entry name" value="AlkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57884">
        <property type="entry name" value="SSF57884"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00516">
        <property type="entry name" value="ALKYLBASE_DNA_GLYCOS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="11">
        <location>
            <begin position="98"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="511"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN56719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="535" mass="57968" checksum="A379C661E8E9CAE3" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEK9</accession>
    <name>A0A0S2DEK9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_07745</name>
        <name evidence="2" type="ORF">GLE_1473</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946804.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56830">
        <property type="protein sequence ID" value="ALN56830"/>
        <property type="gene ID" value="GLE_1473"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1473"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1454"/>
    <dbReference type="OrthoDB" id="2069097at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="120" mass="12761" checksum="4029B2E92476E916" modified="2016-02-17" version="1">MAVDRRAGYGLSAPDDLIDPEPSRGRLFGALAWCALLLGPAAAWLVVFGFTPDGECGDWSLHCTGKAIMYSAASWLFGSLLAIVALFRGERRGLAVPALVLNLIPLLGLLAAYLFLAERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DER3</accession>
    <name>A0A0S2DER3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein phosphatase 2C domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_08125</name>
        <name evidence="1" type="ORF">GLE_1555</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946873.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1555"/>
    <dbReference type="EnsemblBacteria" id="ALN56912">
        <property type="protein sequence ID" value="ALN56912"/>
        <property type="gene ID" value="GLE_1555"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1555"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1536"/>
    <dbReference type="OMA" id="CQDAHHW"/>
    <dbReference type="OrthoDB" id="1835483at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="253" mass="26154" checksum="1B9CBF3EC3007724" modified="2016-02-17" version="1">MGWRIYAASAVGTSHLDKGIPCQDACAFHVEGELLAAVVCDGAGSAARSDVGARLIADGLARALGERLAREPELLAGPREDFAAAAAEAVAQARAALVERADADGRALGDYAATVVGYAGDAQSGWFLHIGDGIGVAEAVDADAAAPVVSLPANGEYANETWFVTGEGWREQLRVLRVPAPTARLALMSDGAMPFAMARGNAALYAPFIDPVSRYLASVDEDTGSRALHGTLADPRTHGITSDDKTLLIALRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DER6</accession>
    <name>A0A0S2DER6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribonuclease 3</fullName>
            <ecNumber evidence="7">3.1.26.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Ribonuclease III</fullName>
            <shortName evidence="7">RNase III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">rnc</name>
        <name evidence="12" type="ORF">BV903_13280</name>
        <name evidence="11" type="ORF">GLE_1710</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">B25</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribonuclease III family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.3" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000034">
        <property type="protein sequence ID" value="OPD63400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1710"/>
    <dbReference type="EnsemblBacteria" id="ALN57065">
        <property type="protein sequence ID" value="ALN57065"/>
        <property type="gene ID" value="GLE_1710"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63400">
        <property type="protein sequence ID" value="OPD63400"/>
        <property type="gene ID" value="BV903_13280"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1710"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1688"/>
    <dbReference type="OMA" id="LTHKSCK"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00104">
        <property type="entry name" value="RNase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011907">
        <property type="entry name" value="RNase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11207">
        <property type="entry name" value="PTHR11207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00035">
        <property type="entry name" value="dsrm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14622">
        <property type="entry name" value="Ribonucleas_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00358">
        <property type="entry name" value="DSRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="SSF69065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02191">
        <property type="entry name" value="RNaseIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4 7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="RNase III" evidence="10">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="DRBM" evidence="9">
        <location>
            <begin position="148"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN57065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OPD63400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="220" mass="23851" checksum="57B7294B30E9D49B" modified="2016-02-17" version="1">MTDPISHRFANPALLEQALTHRSAGAPHNERLEFLGDALVNLIVAEALYQRWPQADEGALTRARAELVRESALAPIARTLELGARLTLGPGEMKSGGHRRDSILADALEAVVGAIYLDAGFETCRAQVLPWFVPAMEALPPAHKVGKDAKTRLQEWLQGRQKPLPLYALLAESGEDHAKTFRVSCTVGQPPLSAEGEAGSRRAAEQLAAEEVLRLLKADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEW9</accession>
    <name>A0A0S2DEW9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Large ribosomal RNA subunit accumulation protein YceD</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">23S rRNA accumulation protein YceD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_1687</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a role in synthesis, processing and/or stability of 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DUF177 domain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1687"/>
    <dbReference type="EnsemblBacteria" id="ALN57043">
        <property type="protein sequence ID" value="ALN57043"/>
        <property type="gene ID" value="GLE_1687"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1687"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1665"/>
    <dbReference type="OMA" id="TLLCQRC"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003772">
        <property type="entry name" value="YceD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039255">
        <property type="entry name" value="YceD_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38099">
        <property type="entry name" value="PTHR38099"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02620">
        <property type="entry name" value="YceD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="170" mass="18832" checksum="09603B98E7301919" modified="2016-02-17" version="1">MPPGRVPEVLDAWRLVAARRGVEGRLPLSALTRLQGLLYDVDGEVRFSLDFDTDELRVPYAELKIEAGLPLLCQRSLERFVMPVRIEQRLGLIRDEADEAALPPGYEPLLMPEDGMLRPAEMVEDELILAVPVVPVAPDSEAVERDFSATQVELDAANPFAALSSLKKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF56</accession>
    <name>A0A0S2DF56_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arc family DNA binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_08255</name>
        <name evidence="2" type="ORF">GLE_1586</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="QCW25662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946899.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56943">
        <property type="protein sequence ID" value="ALN56943"/>
        <property type="gene ID" value="GLE_1586"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1586"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1566"/>
    <dbReference type="OMA" id="NAHIEFL"/>
    <dbReference type="OrthoDB" id="2101132at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
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        <property type="entry name" value="Ribbon_hlx_hlx"/>
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        <property type="match status" value="1"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="65" mass="7407" checksum="B7B57C3BC6EA525B" modified="2016-02-17" version="1">MSEKKAYPLRINAEVLAAAQRWADDELRSLNAQIEYVLREALRRNGRLPRQQPPPSPPPSPEEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF59</accession>
    <name>A0A0S2DF59_LYSEN</name>
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        <submittedName>
            <fullName evidence="6">RNA polymerase sigma factor, sigma-70 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_1785</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1785"/>
    <dbReference type="EnsemblBacteria" id="ALN57139">
        <property type="protein sequence ID" value="ALN57139"/>
        <property type="gene ID" value="GLE_1785"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1785"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1759"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="4">
        <location>
            <begin position="139"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="5">
        <location>
            <begin position="236"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="19"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="295" mass="32110" checksum="C8E0C75181F6603F" modified="2016-02-17" version="1">MWPDHSSRPRALQAARAAAAALHPRAAPDRIDLQPRPRSPLDSAMPLVSAACRPLPSPRPFAAGFGAAAAAPDGRADLPNPLASWLESPHSRAVAARITEAQMTESTATQSGLPAAGDDAAAQLLGAIARGDRAAFERLYRDTSARLFGVCLRLLPERAEAEDVLQEVYATVWRKAGQFDAGRASAAVWLAMIARNKAIDRLRAMPALRRAPLELSEELADAAPTPAAQAERLDERERLRRCLDELDARRRDLIRTAFFEGCTYEELAQRSGSPLGSVKSWIRRGLIQLRACLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF73</accession>
    <name>A0A0S2DF73_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Adenylate cyclase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">CYTH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_08880</name>
        <name evidence="3" type="ORF">GLE_1717</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947001.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1717"/>
    <dbReference type="EnsemblBacteria" id="ALN57072">
        <property type="protein sequence ID" value="ALN57072"/>
        <property type="gene ID" value="GLE_1717"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1717"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1695"/>
    <dbReference type="OMA" id="WEVDEFF"/>
    <dbReference type="OrthoDB" id="1469073at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033469">
        <property type="entry name" value="CYTH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023577">
        <property type="entry name" value="CYTH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012042">
        <property type="entry name" value="NeuTTM/CthTTM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40114">
        <property type="entry name" value="PTHR40114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01928">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016487">
        <property type="entry name" value="CYTH_UCP016487"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01118">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55154">
        <property type="entry name" value="SSF55154"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51707">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTH" evidence="2">
        <location>
            <begin position="2"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR016487-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="170" mass="18925" checksum="5CB72C6A6A1547DF" modified="2016-02-17" version="1">MGIEIERKFLVTSDAWRAAAHKVVPMAQGYLNDLAAMDTGAMKASVRVRIAGEDAFLNLKSRELGHTRQEFDYPIPERDARDLLALCVGGLVDKRRHYVEHAGFVWEVDEFLGDNAGLVVAEVELPSADAAFDKPVWAGREVTESARYYNLALATRPFSQWSQAERDGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFD9</accession>
    <name>A0A0S2DFD9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1949</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57300">
        <property type="protein sequence ID" value="ALN57300"/>
        <property type="gene ID" value="GLE_1949"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1949"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1914"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="296" mass="31381" checksum="9E073B81187EC67F" modified="2016-02-17" version="1">MPSPAQRGRIDAAAAGCVMIACPAATGRRPDAATAGPANRGRAAAGAGSAPDRTAAPQRCVAATGPFRACAAGRRRHFTFVPLDAFSLRKAAMNLPTAPLSRTARRLALAALLAGLSACVAFERVPVAELRCDPDLAGAWTVKAGNGLKKTAHIDARCHTDDWPGMSDKPVALDLTGFVIGQDRYLALTPVQAQLAMGADPGALTEGLPKDAVFLVLYRLGPDGRLQAWLPDSKRALDAIARGELDGRRLKEQFALIQGTPEQLRDTLAQRLNLLYDTDRQAMVFERAKAARQDSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFM8</accession>
    <name>A0A0S2DFM8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">PAAR motif family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_19545</name>
        <name evidence="1" type="ORF">GLE_2046</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000056">
        <property type="protein sequence ID" value="OPD62253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57396">
        <property type="protein sequence ID" value="ALN57396"/>
        <property type="gene ID" value="GLE_2046"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62253">
        <property type="protein sequence ID" value="OPD62253"/>
        <property type="gene ID" value="BV903_19545"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2046"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2011"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008727">
        <property type="entry name" value="PAAR_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05488">
        <property type="entry name" value="PAAR_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD62253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="100" mass="10460" checksum="93474769F23A1284" modified="2016-02-17" version="1">MTRYWIQAGDTTSGGGSVLAQGAGGDGRPRWARIGDAVHCGMHGMTTIVTGDAEQRIDGRAVARHGDFCACGCILISLSQIRSIVELGTDLIAPPHARRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFQ3</accession>
    <name>A0A0S2DFQ3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transporter, major facilitator family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_1830</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1830"/>
    <dbReference type="EnsemblBacteria" id="ALN57182">
        <property type="protein sequence ID" value="ALN57182"/>
        <property type="gene ID" value="GLE_1830"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1830"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1801"/>
    <dbReference type="OMA" id="TPDDMRG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="244"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="281"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="396"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="1"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN57182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="430" mass="45077" checksum="96388305CBC99273" modified="2016-02-17" version="1">MSEAVARADRPQDPDAGGPVSASQLLRNPGFVGLLVYRLLAMLSYQIVAVTVGWHVYELTRDPLALGMIGLTEVVPYFCFALFAGYAVDHLPRRKLGMFACLGLLVTTLMLAGVASGTLPAGAFGIGTFTIFAAIAINGVVRAFLSPVYMSLFARVLKREHFARGAGVSSVVMQTGLVMGPALGGVLVAWGGKTSAYLVAAAFALAAAIAIVSLRVTEPPPPAERAPVFQSIGEGLRFVFNNQVVLGAQALDMFSVLFGGAVALLPAFIHDVLHYGPEALGVLRAAPAAGAVLMGLWLARHPPQKHAGRLLLWAVAGFGLCIVGFALSREFWLSAAMLMLSGMCDGVSVVLRSTILQLSTPDEMRGRVSSINGIFIGSSNELGAFESGLAAKLMGLVPSVIFGGCMTLAVVGATAKLAPKLRRLDLRDLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFS4</accession>
    <name>A0A0S2DFS4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2043</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947239.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57393">
        <property type="protein sequence ID" value="ALN57393"/>
        <property type="gene ID" value="GLE_2043"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2043"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2008"/>
    <dbReference type="OrthoDB" id="1089166at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012467">
        <property type="entry name" value="DUF1684"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41913">
        <property type="entry name" value="PTHR41913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07920">
        <property type="entry name" value="DUF1684"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594958" evidence="1">
        <location>
            <begin position="27"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="292" mass="31447" checksum="CA9D080E12889210" modified="2016-02-17" version="1">MRLPSPSIRTRLALALLLALPLAAQADPRKDYDEFRAGLTQQASGATGMYAIQDVRVIAAGAGAHLPAGAPAAALRWADGAGGAKDVRLRFRDGAAMLEGPGLKPVDLLKAPDHTQALAGGLSVRATVYDDALKAWLYNPARVGQTFKGLSFFPYDPKGVVQARFARRPAKAVSHLDSRNHTGTMYWIGDVALPLQGKTYTLRAFNKSGDWSGIDHLLLFFTDKTSKKTSYGGGRVLEAHFPAGQPPQTLSLNLNMLYSFLCAHSDYYNCPVNLTTYVPVALEFGEKYPPGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFW0</accession>
    <name>A0A0S2DFW0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2091</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2091"/>
    <dbReference type="EnsemblBacteria" id="ALN57441">
        <property type="protein sequence ID" value="ALN57441"/>
        <property type="gene ID" value="GLE_2091"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2091"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2056"/>
    <dbReference type="OMA" id="RHRWLGW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004792">
        <property type="entry name" value="BaiN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022460">
        <property type="entry name" value="Flavoprotein_PP4765"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023166">
        <property type="entry name" value="HI0933-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42887">
        <property type="entry name" value="PTHR42887"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03862">
        <property type="entry name" value="flavo_PP4765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00275">
        <property type="entry name" value="TIGR00275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="396" mass="43015" checksum="D2F35A4E757B1501" modified="2016-02-17" version="1">MAAHAARALGVEVDLFEAKGSVGRKFLIAGKGGLNLTHGEPRPGFDARYRERAGEVARWLDRFDADALREWARGFGVQTYVGSSGRVFPTDRKAAPLLRGWVRRLREDGVRFHVQHRCTGLDADGTLRFHTPDGEARTRARACVLALGGGSWPQLGSDGAWVEWLRERGLDIAPLQPSNCGFDVGWSEHFAQRHAGAPLKPVVAHWREHGEERSLQGECVATASGIEGSLVYALSAMLRERIATHGEATLELDLAPGRELERLQRDFARPRGGRSIGEHLRRQTGLDAVKAALVFEVLGKDGLNDAATVARTIKRLPLRLLRARPIAEAISSAGGVRLQALDDSLRVREFAPALFCAGEMLDWEAPTGGYLLTACFASGLIAGEAAARALLENASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFY9</accession>
    <name>A0A0S2DFY9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8 9">Translation initiation factor IF-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">infB</name>
        <name evidence="12" type="ORF">GLE_2176</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 9">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947339.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2176"/>
    <dbReference type="EnsemblBacteria" id="ALN57525">
        <property type="protein sequence ID" value="ALN57525"/>
        <property type="gene ID" value="GLE_2176"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2176"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2138"/>
    <dbReference type="OMA" id="NRDNRTG"/>
    <dbReference type="OrthoDB" id="347113at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03702">
        <property type="entry name" value="IF2_mtIF2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00100_B">
        <property type="entry name" value="IF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044145">
        <property type="entry name" value="IF2_II"/>
    </dbReference>
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        <property type="entry name" value="IF2_N"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000178">
        <property type="entry name" value="TF_IF2_bacterial-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="PTHR43381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04760">
        <property type="entry name" value="IF2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="SSF52156"/>
        <property type="match status" value="1"/>
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    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00487">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01176">
        <property type="entry name" value="IF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 8 9" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="11">
        <location>
            <begin position="390"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="126"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="257"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="G-domain" evidence="8">
        <location>
            <begin position="393"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="126"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="263"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="399"/>
            <end position="406"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="445"/>
            <end position="449"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="499"/>
            <end position="502"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN57525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="891" mass="94828" checksum="E4740A47C18506C4" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG03</accession>
    <name>A0A0S2DG03_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alcohol dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_2194</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.1" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2194"/>
    <dbReference type="EnsemblBacteria" id="ALN57543">
        <property type="protein sequence ID" value="ALN57543"/>
        <property type="gene ID" value="GLE_2194"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2194"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2156"/>
    <dbReference type="OMA" id="QYAHNVF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
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        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
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        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="3">
        <location>
            <begin position="12"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="343" mass="36559" checksum="23929B27E940F4A4" modified="2016-02-17" version="1">MKMKAIVMTGAGRPWEVHEVPVPAVEPGQVLVRVHASGMCYTDVWATQGYGGDIYPQTPGHEVVGEVVEVGAGVRSRRVGDRVGTTWVQSACGRCPYCRQNRPLSGQTAMNCVEPRTTGFAAQGGHAEYIAIAAEGTVLLPDGLAYADAAPMMCAGYTTWSGLRDAQPQPRERIAVLGIGGLGHVALQLSRACGYDTVAITHSADKHDLARQLGADNVVADGRELREIGGADVLLVTSNDFESAQEAVAGLRVDGRIVLCGLDFSRPFSISSEGVPFHMMRQRVIGATHGGQRYLSEVLELAAQGKVKPIVETFALDQAAEAYERLASGRMRFRGVFTPSHGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG47</accession>
    <name>A0A0S2DG47_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_2106</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell inner membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947285.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000080.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57456">
        <property type="protein sequence ID" value="ALN57456"/>
        <property type="gene ID" value="GLE_2106"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2106"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2070"/>
    <dbReference type="OMA" id="GVWFSLE"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00164">
        <property type="entry name" value="ABC2TRNSPORT"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="237"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="351" mass="37931" checksum="A0E29A69CFEB7BC1" modified="2016-02-17" version="1">MIGKTWVFFKLRMLQISYDKSALFFCYVLPVLLLLGVGYAGDSRIALAYGGDAATAEAKALVAYLDKHELVKLERYADAATPAREALQNNQLKHYLEFAAPGAGAPARLYANSLAENRVENTALQSVLDGYYRKGAAPAGPQQETVAIGKFGSKIISLLPGLIGMTLLIVGLNGFGALLIEEEHHGLYKNIKTIDVSPVPFLAGLFMSRMMIAYSVAASLYLLGIFVFGVPFDINYLLLLFVLTLGAVSFLAMGLAFATISPSVTAFTGITNFVQMPLILLGGVFFSVKALPEWVQWIAVGTPLAQFNTALQAILFDSVGFADLGKVLPQVAGLMGWSALALLVARFRFRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGA6</accession>
    <name>A0A0S2DGA6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57475">
        <property type="protein sequence ID" value="ALN57475"/>
        <property type="gene ID" value="GLE_2125"/>
    </dbReference>
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</entry>
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            <authorList>
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                <person name="Fernandez C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 7">B25</strain>
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        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
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                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 9">YC36</strain>
        </source>
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        <property type="gene ID" value="BV903_10735"/>
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        <source>
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        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
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    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
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    <sequence length="103" mass="11414" checksum="59D58E8611803EE0" modified="2016-02-17" version="1">MKIQLNTDHHVRGDDSLEHHVEGVIDQNLGRFREQITRIEVHLRDLNGEKSGGHDKHCTIEARLEGRPPMAATEDAATMRAAISGAARKLQRVLDSSLGRLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGH3</accession>
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            <fullName evidence="6">Polysaccharide biosynthesis protein</fullName>
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    </protein>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <source>
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    </evidence>
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    <sequence length="431" mass="44446" checksum="F05DAD0DFED7319D" modified="2016-02-17" version="1">MMRRLIGTASLSAVSAMASRGALFAGVLAAAHYLGPAAFGQFTLIQTTALLFTTFCALSLGQMATKIVAEAVARGDRGRVSAALTVSYGSALLASLVFAALLLACAYPLAVKLGGSADLAVVYASSSLLVLTGFVGAIQNGVALALHKVKQQAAANLLTAPVVFAIMWGAATRRDIGWAMYGAIAAQWLIVLGQERVLRRYRREHGEPLAWSATTREDWAVVWRLGLPSSLSGLLTMPAIWLSMAMLAHSARGEAELGHFALGNQARSILLFGMGVVANAALPMLSAAIVRGAREEAASTLRQSIALLVAVTAGLAGVLGLAAPLAVARFAPAYAEAVVPLQWLLLSAVATAPTTILMRKATADARPAVMLLGNAAFAVSLIGAAALALELGHGATGVAIAYAIASTVQLIVFAACNRRELRWPAAAGKSP</sequence>
</entry>
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    <accession>A0A0S2DGM3</accession>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
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            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="137" mass="15071" checksum="9658D5F276905A63" modified="2016-02-17" version="1">MHIRPALSCAIALTACFAAATHAAAPAPKPEALRASYQRCLADSGGVTPAMQDCLDTEYAYQDGRLNQVYRRLIQRLSKPEAARLRECQRAWIGQRDRACDPGTRPGQGQLFDADNCRLRKTAERAAQLQAQLASTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGW2</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2243</name>
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    <organism evidence="2 3">
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            <taxon>Gammaproteobacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57592">
        <property type="protein sequence ID" value="ALN57592"/>
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            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="298" mass="32510" checksum="961089BD6CB4670A" modified="2016-02-17" version="1">MRRPAAPGDRTRRRDRRVTPPTKRAQARETAECRYVPSFRPALEHRVPDRGVRHRIAREVAASAADAFTATLSHTGIEHRRLMARQDPVGAVASRSDERIQLEPHRLGQGAIDLDRSNVTRILQKGLVQRPRAPRVLARSDGAGPLLHRVPGVFGPAVRGALPVVAGASPDVDELVDGLGRARGRTRAEHGAHLVSRAHIGQALQRLRLAVETDVDDGVFPADRDAPRRNFDDLADVDALVGSGSGRSGEQKQQRNNGGRRFHRWRTSIAQRGMAARGFAPTADIGTTAVKAPRGGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGW4</accession>
    <name>A0A0S2DGW4_LYSEN</name>
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        <submittedName>
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        <submittedName>
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        </submittedName>
    </protein>
    <gene>
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        <name type="scientific">Lysobacter enzymogenes</name>
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            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="11 13">YC36</strain>
        </source>
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    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_2561"/>
    <dbReference type="EnsemblBacteria" id="ALN57910">
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        <property type="gene ID" value="GLE_2561"/>
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    <dbReference type="OMA" id="GWADTAV"/>
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        <property type="component" value="Chromosome"/>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
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    </feature>
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        </location>
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            <end position="554"/>
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        </location>
        <ligand>
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        </ligand>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN57910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW26423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="554" mass="60522" checksum="4F39A5B0F3A7BBDB" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGY9</accession>
    <name>A0A0S2DGY9_LYSEN</name>
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        </submittedName>
        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nolNO</name>
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        <name evidence="5" type="ORF">GLE_2512</name>
    </gene>
    <organism evidence="5 7">
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        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NodU/CmcH family.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.-" evidence="5"/>
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    </dbReference>
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        <property type="protein sequence ID" value="QCW26382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="protein sequence ID" value="ALN57861"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="InterPro"/>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbam_trans_N" evidence="3">
        <location>
            <begin position="21"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="Carbam_trans_C" evidence="4">
        <location>
            <begin position="385"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW26382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="659" mass="73583" checksum="CB54D7D082388D66" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH59</accession>
    <name>A0A0S2DH59_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2431</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947534.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57780">
        <property type="protein sequence ID" value="ALN57780"/>
        <property type="gene ID" value="GLE_2431"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2431"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2393"/>
    <dbReference type="OrthoDB" id="1083580at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="484"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="504" mass="55883" checksum="4663E8E66D4194EF" modified="2016-02-17" version="1">MAAPDCMRAVPGAARAANGSNLMGFTLEEKTLKSGETVTLVHWEDLSPTRHGKALQDRDWDGSGNRKGLSFYDSTSEYMHNSWASEHMAPQGVTLPGKGSLMLYHHEQTGTWHSADALDIDHVAQWKDHFVERGVKSQAEAMMAYNDVDNLRLLPAPVNRARDAAFRVLDTHGADSPEWKQWVEDRFAFDPKTNRPGFDPDVDGSVRKRTTMEQPWKPEDGRSGLSFDAAVLGKWYQAKLQECYAGEVEVRHPQTGDKSKVPLFFCQASGQLCTRDAFDIDHEIPFELLGPEMAKHAGRDGLSKADALDGYNDTSNLRLVARGVNSSHDFEIQASGDYRDEKIAPEKRGEFKGFLGEESGLLSPQLKQQLRELGRNYPSPQQLMSDFGQPGYGPYTQALGKLEQTGFGQAMTAQERSNVAGTLAVAATHYRLNIDHVAQSDDGSRVFAIQGDPKNNQFVWADAQGAKQQSLAQSTVDLNRIVHEQNNPSGPQLNQQQQRNATLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHA2</accession>
    <name>A0A0S2DHA2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_12385</name>
        <name evidence="2" type="ORF">GLE_2479</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947568.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2479"/>
    <dbReference type="EnsemblBacteria" id="ALN57828">
        <property type="protein sequence ID" value="ALN57828"/>
        <property type="gene ID" value="GLE_2479"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2479"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2441"/>
    <dbReference type="OrthoDB" id="1911841at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="147" mass="14702" checksum="9EEA4FD5DF114816" modified="2016-02-17" version="1">MAILRGEGIGDDAVALVARSDIELEAIPDRHKQADTDFIPAAIRGAGVGGATGLLAGLAATVIAPLGITLAGAAMVAAVGAAVGTWASALMGSSLPDPVRQQFEDEIAAGRILLVLDLAPAEHARLRPLLETSGAQALDYAAPAAMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHA8</accession>
    <name>A0A0S2DHA8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947533.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2430"/>
    <dbReference type="EnsemblBacteria" id="ALN57779">
        <property type="protein sequence ID" value="ALN57779"/>
        <property type="gene ID" value="GLE_2430"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2430"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2392"/>
    <dbReference type="OMA" id="YLCAIHQ"/>
    <dbReference type="OrthoDB" id="2084663at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="181" mass="19709" checksum="3FC5CA1B711AE584" modified="2016-02-17" version="1">MRTRSPPASPAPDPSAPAPEPALAATAQTAARDALAQWRELTRQANAAFDRRQLAHAQRLYRQALRVVDAPDWRAALAVAPDELLAARVVSHHNLAETHRRQRDPERAREQLCLAHEALTGIACDPRAGDAVRRCALRHLGRTRLALLDWQSARGVCARTQVALRESAAALARSDAGPATH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHD0</accession>
    <name>A0A0S2DHD0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Polysaccharide biosynthesis/export protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Sugar transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_12275</name>
        <name evidence="4" type="ORF">GLE_2457</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947551.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2457"/>
    <dbReference type="EnsemblBacteria" id="ALN57806">
        <property type="protein sequence ID" value="ALN57806"/>
        <property type="gene ID" value="GLE_2457"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2457"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2419"/>
    <dbReference type="OMA" id="DVKFFYN"/>
    <dbReference type="OrthoDB" id="687725at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015159">
        <property type="term" value="F:polysaccharide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003715">
        <property type="entry name" value="Poly_export"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019554">
        <property type="entry name" value="Soluble_ligand-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02563">
        <property type="entry name" value="Poly_export"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10531">
        <property type="entry name" value="SLBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242145" evidence="2">
        <location>
            <begin position="25"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="SLBB" evidence="3">
        <location>
            <begin position="117"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="237" mass="25325" checksum="B16187C1D4F0CF23" modified="2016-02-17" version="1">MLLATLLMLLCLLASGLAAAPAFAQAPAPAAAAAAADAGYRIAAGDELALKFFYAPELNETATVRPDGRIQLQLVGEVRAAGQTPRELADALKRAYAGSLRYPEVSVEVEKGFARQQVFVGGEVGRPGAQPLLPGLTLMRALIVAQGPTDRAALNRVAILRRDESGATRVIRVDAASQARRGADDGNDPPLQPFDVVLAVPSRISRVNKWIDQYVRRNLPVNVGFSYDLNDNNRRGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHE5</accession>
    <name>A0A0S2DHE5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kynurenine 3-monooxygenase</fullName>
            <ecNumber evidence="4">1.14.13.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Kynurenine 3-hydroxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">kmo</name>
        <name evidence="7" type="ORF">FE772_13420</name>
        <name evidence="6" type="ORF">GLE_2679</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>H(+) + L-kynurenine + NADPH + O2 = 3-hydroxy-L-kynurenine + H2O + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:20545"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57959"/>
            <dbReference type="ChEBI" id="CHEBI:58125"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.13.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the aromatic-ring hydroxylase family. KMO subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.9" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947729.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2679"/>
    <dbReference type="EnsemblBacteria" id="ALN58027">
        <property type="protein sequence ID" value="ALN58027"/>
        <property type="gene ID" value="GLE_2679"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2679"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2638"/>
    <dbReference type="OMA" id="REFMFIA"/>
    <dbReference type="OrthoDB" id="504558at2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00328"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004502">
        <property type="term" value="F:kynurenine 3-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034354">
        <property type="term" value="P:'de novo' NAD biosynthetic process from tryptophan"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043420">
        <property type="term" value="P:anthranilate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019805">
        <property type="term" value="P:quinolinate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006569">
        <property type="term" value="P:tryptophan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01971">
        <property type="entry name" value="Kynurenine_monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027545">
        <property type="entry name" value="Kynurenine_monooxygenase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 4" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="5">
        <location>
            <begin position="12"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW26512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="457" mass="51006" checksum="809C0BE2A97B5344" modified="2016-02-17" version="1">MNTSANATPHITLIGAGLAGALLATLLARAGWRVDVYEKRGDPRLKGYQGGRSINLALAERGRHALRLAGADEAVMAQAVMMRGRMVHFLDGRTDLQRYGRDDSEVIWSVHRGELNLILLQIAQDAGANLHFHRGLSGVDFDARIARFRDDRDGSEHEVAFDSLVGADGAGSALRAAMGEVADLGERTEFLGHSYKELEIPPARDGGFSIEPNALHIWPRGRYMCIALPNDERTFTVTLFLPNQGDPSFETIRDGADARALFQRDFADALPLIPELERDFERNPAGLLATLYLERWHLDDRAVLLGDAAHAMVPFHGQGMNCAFEDCVALAERLLAGGDRGDAFAAFQRQRLPSARAIQAMALENYLEMRDRVDDDDYLLQRALERELAQRHPERFMPRYAMVTFHRMPYEVAFDRGQRQRELLVELTRGHDSLDSLDWDAVDATVRARLDPLPADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHG8</accession>
    <name>A0A0S2DHG8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Thioesterase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_2555</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioesterase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2555"/>
    <dbReference type="EnsemblBacteria" id="ALN57904">
        <property type="protein sequence ID" value="ALN57904"/>
        <property type="gene ID" value="GLE_2555"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2555"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2515"/>
    <dbReference type="OMA" id="GQHFFIR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020802">
        <property type="entry name" value="PKS_thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012223">
        <property type="entry name" value="TEII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11487">
        <property type="entry name" value="PTHR11487"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00824">
        <property type="entry name" value="PKS_TE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_TE" evidence="3">
        <location>
            <begin position="24"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="257" mass="28539" checksum="8BBB34C0E2D67019" modified="2016-02-17" version="1">MQMIVIWIYGVQLMPVTQSLPRLICLPYAGGSWHAFAPWQAALQGQLEVVAPELPGRGHRIAEAPFSRLPALVDWLLDELDAQLADDFSLWGHSMGALLAYETARTLERRGRRGPRHLFVTGALPPRYPRHAERYHLLDDDGLIAKLAAMGGTPEEVLRDRDLMQIVLPFVRADFAVCETYAWDSREPAVRAPITAIGGDRDPDIAIDKLHGWNDCSRAGARVSSLPGGHFFLRDHVAALADVFTRTLARPALREPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHH2</accession>
    <name>A0A0S2DHH2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57870">
        <property type="protein sequence ID" value="ALN57870"/>
        <property type="gene ID" value="GLE_2521"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2521"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="37" mass="3996" checksum="3D51C4C21F0AD5D9" modified="2016-02-17" version="1">MVRAGLIGAGSQATHAGIAGSGRHSSLPVRRRRWRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHN6</accession>
    <name>A0A0S2DHN6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58183">
        <property type="protein sequence ID" value="ALN58183"/>
        <property type="gene ID" value="GLE_2835"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2835"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2793"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046116">
        <property type="entry name" value="DUF6053"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19523">
        <property type="entry name" value="DUF6053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="59" mass="6140" checksum="8AB7383137526E00" modified="2016-02-17" version="1">MIRAVVGGTSVPMLSARIAATWNKSIGTEVPPTVASRAACHIAITQSPLPSHPRAMTMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DID4</accession>
    <name>A0A0S2DID4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2846</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58194">
        <property type="protein sequence ID" value="ALN58194"/>
        <property type="gene ID" value="GLE_2846"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2846"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2805"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="37" mass="4256" checksum="854B6444FA6487F1" modified="2016-02-17" version="1">MPPPPWVAPLAHLIVFALAVKYGYHSKEREYSKFPSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIN9</accession>
    <name>A0A0S2DIN9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3024</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58372">
        <property type="protein sequence ID" value="ALN58372"/>
        <property type="gene ID" value="GLE_3024"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3024"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2985"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="85" mass="9916" checksum="8ED50FDFC74E9D44" modified="2016-02-17" version="1">MRSPRRRRWEADAMPKADATKLTYRRSREGGNPWLHRDMALKSLDPRVRGDDDLGEPRREPSVVVTHLTSFPRRREPRASSRHGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIV3</accession>
    <name>A0A0S2DIV3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3127"/>
    <dbReference type="EnsemblBacteria" id="ALN58474">
        <property type="protein sequence ID" value="ALN58474"/>
        <property type="gene ID" value="GLE_3127"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3127"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3083"/>
    <dbReference type="OMA" id="HLSWNAR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="302" mass="32658" checksum="61887E2AFB9EB0DF" modified="2016-02-17" version="1">MLALAARIRRRSRAPPVGRCVARKRPRGDAETSARAAMLARRMDCPRPHGARRETAPMDTDSAQRRPPTPPAVPRDAAGRDAAGVENKAAGFAGEFETHLTVAADRDGALQRFAAAHGLKCLHIELARGAQPLQPMLSWRGRGEFAQQRARAQAIAAQLRAAGLAPTRIKIEAAPGNRGVPRDDADAGAGRYFESHIKLLLPAGADLAALAARVAGHGAHLSRNALRTREDGLDERFVTQRSRGGLERAYAQLRALLDELDAMDLRRLGAETEYVVYDDNLAVDDGWINMGTDDPLARRAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ87</accession>
    <name>A0A0S2DJ87_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Succinyl-diaminopimelate desuccinylase</fullName>
            <ecNumber evidence="5">3.5.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">GLE_3349</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + N-succinyl-(2S,6S)-2,6-diaminoheptanedioate = (2S,6S)-2,6-diaminoheptanedioate + succinate</text>
            <dbReference type="Rhea" id="RHEA:22608"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57609"/>
            <dbReference type="ChEBI" id="CHEBI:58087"/>
            <dbReference type="EC" id="3.5.1.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (succinylase route): step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M20A family. DapE subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.18" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3349"/>
    <dbReference type="EnsemblBacteria" id="ALN58695">
        <property type="protein sequence ID" value="ALN58695"/>
        <property type="gene ID" value="GLE_3349"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3349"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3299"/>
    <dbReference type="OMA" id="LNSHHDT"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00021"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009014">
        <property type="term" value="F:succinyl-diaminopimelate desuccinylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005941">
        <property type="entry name" value="DapE_proteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01246">
        <property type="entry name" value="dapE_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0170">Cobalt</keyword>
    <keyword evidence="11" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="M20_dimer" evidence="15">
        <location>
            <begin position="106"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00031891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ALN58695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="306" mass="33088" checksum="0ABF42F9A24F4C43" modified="2016-02-17" version="1">MPSGPVESWASDPFAPQVRDGVLYGRGAADMKGSVAAFVVALERFAAAHPRHRGRVALLLTSDEEGDAIDGVRRVAETFRARGERIDWCVTGEPSSTRTLGDLLRVGRRGTLSATLKVIGVQGHVAYPDKARNPIHQAMPALSELAARRWDEGYETFPPTSLQISNIHAGTGANNVIPGELQVLFNLRYNPSWNAQRLEQECEAVLDAHGLQYELAWFRGGEPFYTPEGPLRAAAREVLARFAGAAPEESTGGGTSDARFIAPLGAQCIEIGPVNASIHKVDENVSVADLEALPDLYLALIERLML</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJB5</accession>
    <name>A0A0S2DJB5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rhs family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3276</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948172.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58622">
        <property type="protein sequence ID" value="ALN58622"/>
        <property type="gene ID" value="GLE_3276"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3276"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3229"/>
    <dbReference type="OMA" id="TMQFKAT"/>
    <dbReference type="OrthoDB" id="83874at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032812">
        <property type="entry name" value="SbsA_Ig"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13205">
        <property type="entry name" value="Big_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="SSF117281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Big_5" evidence="2">
        <location>
            <begin position="245"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1487" mass="154264" checksum="0870E133D749A8BB" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJG9</accession>
    <name>A0A0S2DJG9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat-containing exported protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_3330</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3330"/>
    <dbReference type="EnsemblBacteria" id="ALN58676">
        <property type="protein sequence ID" value="ALN58676"/>
        <property type="gene ID" value="GLE_3330"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3330"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3280"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595112" evidence="3">
        <location>
            <begin position="39"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="202"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="260"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="283" mass="28827" checksum="FD96783B16A8C740" modified="2016-02-17" version="1">MNTHRADAAGARRGPDRAWALCAALCAALAAAAGCAGARAPEAAPALAAGRCPPKDLRTLDRPGGDALHRAVADADLAATRRALAAGSDPNGRDGYEDTALAAAVAAEVYAFRERSPRQLRELAAQDAARARAQLDIVRALLDAGADPDGRSRYGDTALIRVAGAALPIDEESFAAAAAAQRRALVALLLERGARIDQGNDRGATALMAAAGNDRLAAALVATLLGRGADPRRVDCVGRTALSIARERGRDDAAELLKGALAPATKEPAGSQPAGPPPPKINP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJJ5</accession>
    <name>A0A0S2DJJ5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3227</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58573">
        <property type="protein sequence ID" value="ALN58573"/>
        <property type="gene ID" value="GLE_3227"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3227"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="61" mass="6290" checksum="C367D4B57446CC5F" modified="2016-02-17" version="1">MAGVAIAVGGMSRAPRRRGVNARQRTPRRAAGGAGRSSRACAALRAPGSFRTHWAGRSTDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJP1</accession>
    <name>A0A0S2DJP1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Flagellar motor protein MotB</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">OmpA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_16340</name>
        <name evidence="4" type="ORF">GLE_3303</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948192.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3303"/>
    <dbReference type="EnsemblBacteria" id="ALN58649">
        <property type="protein sequence ID" value="ALN58649"/>
        <property type="gene ID" value="GLE_3303"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3303"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3253"/>
    <dbReference type="OMA" id="GDSQPML"/>
    <dbReference type="OrthoDB" id="1222928at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0282">Flagellum</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726671" evidence="2">
        <location>
            <begin position="24"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="3">
        <location>
            <begin position="323"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="446" mass="47825" checksum="6676866E088984FD" modified="2016-02-17" version="1">MVRAAVSSLLFWFVLLFAAAAPAQEAERVRISGSNTLAHALVPTVAQSWLRDIGYRDIQVRKPRAALTEIHATRDGQPLVVEIAASDSALGFADLVEGHAQIAMMARRPNAAEIDAGWQLGDLASQDQEFVVALDGVAVVVNRANPIARLDLEQLRALFSGRSRDWRELGAAAGEVHLHLDANAGAVRDLMNDKVMRGAAFGEAQMHSDARALIAAVAADPFAVGLVPIGESYGQGARPVAVSDGGRAIAPTRADVLSEDYPLSRRLYLYGGQMMGALSRSFALYSMGRGGQRAVARAGHVAVTLVPGRERALTLGPLEYRQMVERAVRLPLSLRFNFAGSGEAAVAASVYDSRAVRDLDRLRSFMRLPPNRGRSVLVVGFADASAGSPMASMMMSNDRADLVAQELVSRGIKVQVARGMGTALAVAGPRDPLARYRNERVEVWLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJR0</accession>
    <name>A0A0S2DJR0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Uracil phosphoribosyltransferase</fullName>
            <ecNumber evidence="3 11">2.4.2.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">UMP pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">UPRTase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 12" type="primary">upp</name>
        <name evidence="13" type="ORF">BV903_08805</name>
        <name evidence="14" type="ORF">FE772_17340</name>
        <name evidence="12" type="ORF">GLE_3525</name>
    </gene>
    <organism evidence="12 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">C3</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">B25</strain>
        </source>
    </reference>
    <reference evidence="14 17" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>diphosphate + UMP = 5-phospho-alpha-D-ribose 1-diphosphate + uracil</text>
            <dbReference type="Rhea" id="RHEA:13017"/>
            <dbReference type="ChEBI" id="CHEBI:17568"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="11">Allosterically activated by GTP.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uracil: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the UPRTase family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.9" evidence="3 11"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000019">
        <property type="protein sequence ID" value="OPD64276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948355.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3525"/>
    <dbReference type="EnsemblBacteria" id="ALN58869">
        <property type="protein sequence ID" value="ALN58869"/>
        <property type="gene ID" value="GLE_3525"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64276">
        <property type="protein sequence ID" value="OPD64276"/>
        <property type="gene ID" value="BV903_08805"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3525"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3469"/>
    <dbReference type="OMA" id="TYATRMP"/>
    <dbReference type="OrthoDB" id="1581906at2"/>
    <dbReference type="UniPathway" id="UPA00574">
        <property type="reaction ID" value="UER00636"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004845">
        <property type="term" value="F:uracil phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044206">
        <property type="term" value="P:UMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006223">
        <property type="term" value="P:uracil salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01218_B">
        <property type="entry name" value="Upp_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034332">
        <property type="entry name" value="Upp_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005765">
        <property type="entry name" value="Ura_phspho_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01091">
        <property type="entry name" value="upp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="5 11 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11 12" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="5-phospho-alpha-D-ribose 1-diphosphate binding" evidence="11">
        <location>
            <begin position="130"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Uracil binding" evidence="11">
        <location>
            <begin position="198"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>uracil</name>
            <dbReference type="ChEBI" id="CHEBI:17568"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN58869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OPD64276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW27139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="211" mass="22798" checksum="CBA718D8FB58B913" modified="2016-02-17" version="1">MKIVEVRHPLVQHKLGLMRRADNSTKSFRELASEVATLLTYEATADLETEEAVVEGWAGPVTTRRIKGAKVTLVPILRAGLGMLPGVLELIPAAKVGVVGLQRDEQTLQPVGYYEKLTGRMDERTALILDPMLATGGSLIATIDLLKNAGCKRIKGLFLVAAPEGLKALEAKHPDVEVFTASVDERLNEVGYILPGLGDAGDKIFGTKHYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKG7</accession>
    <name>A0A0S2DKG7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_18200</name>
        <name evidence="1" type="ORF">GLE_3694</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59038">
        <property type="protein sequence ID" value="ALN59038"/>
        <property type="gene ID" value="GLE_3694"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3694"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3638"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="126" mass="14320" checksum="0982EAD27FAD8509" modified="2016-02-17" version="1">MGMQAFETTQEIALVVDADAELAHWRSGFRELPHCRSLRWDEVKPALKLGIDACLKANGRDLTEMVEELETRYQRTGNESRLSWSQAREIVAIVWVRIWEQSRSRSATAALAPVPVGRMTLGLRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKS4</accession>
    <name>A0A0S2DKS4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">PAS/GAF domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_3819</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the phytochrome family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948575.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3819"/>
    <dbReference type="EnsemblBacteria" id="ALN59162">
        <property type="protein sequence ID" value="ALN59162"/>
        <property type="gene ID" value="GLE_3819"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3819"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3761"/>
    <dbReference type="OMA" id="ECHRGRI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009584">
        <property type="term" value="P:detection of visible light"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013654">
        <property type="entry name" value="PAS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016132">
        <property type="entry name" value="Phyto_chromo_attachment"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001294">
        <property type="entry name" value="Phytochrome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013515">
        <property type="entry name" value="Phytochrome_cen-reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043150">
        <property type="entry name" value="Phytochrome_PHY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08446">
        <property type="entry name" value="PAS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00360">
        <property type="entry name" value="PHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01033">
        <property type="entry name" value="PHYTOCHROME"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50046">
        <property type="entry name" value="PHYTOCHROME_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0157">Chromophore</keyword>
    <keyword evidence="2" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="5" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0716">Sensory transduction</keyword>
    <feature type="domain" description="PHYTOCHROME_2" evidence="6">
        <location>
            <begin position="143"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="566" mass="60409" checksum="6AAC414D0FAD8C96" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKX4</accession>
    <name>A0A0S2DKX4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3857</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3857"/>
    <dbReference type="EnsemblBacteria" id="ALN59200">
        <property type="protein sequence ID" value="ALN59200"/>
        <property type="gene ID" value="GLE_3857"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3857"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3797"/>
    <dbReference type="OMA" id="WTIASAW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="146" mass="15456" checksum="02BCB3108690E5E4" modified="2016-02-17" version="1">MTVAAPPDRPAPPVAGRVRLYSWLLLALGTFGFAAFWTLAAVSLDRQLAWLAVLGALDIAWMLRLGGWRRGWTRAALGLIATALIVLVANWGIVAGQLSGPFGLDLASSATKLGPNLFWTLFHLANAGPELIWTAIGLVVAAVASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKX6</accession>
    <name>A0A0S2DKX6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytochrome C1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_3599</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3599"/>
    <dbReference type="EnsemblBacteria" id="ALN58943">
        <property type="protein sequence ID" value="ALN58943"/>
        <property type="gene ID" value="GLE_3599"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3599"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3543"/>
    <dbReference type="OMA" id="MPHVLWE"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002326">
        <property type="entry name" value="Cyt_c1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10266">
        <property type="entry name" value="PTHR10266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02167">
        <property type="entry name" value="Cytochrom_C1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00603">
        <property type="entry name" value="CYTOCHROMEC1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594912" evidence="4">
        <location>
            <begin position="20"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="244" mass="27505" checksum="6297DC722F8ABB2E" modified="2016-02-17" version="1">MKKLATFVAGLLVSVTAYASGGGDLLQSGTDLSDRASLQRGAQLYMNYCSGCHSLKYLRYSRMAEDLGLTEDEVMNNLNFTGAKFGEQIQVNLTAEHANQWFGKMPPDLSLITRVRGSDWVYTYLNQFYLDESRPLGWNNKLFPNASMPNPLWELQGLQHAEYGEKDKATGERPVHGLKIEQAGKLDEAGFRTATRDITAFLEYAGEPAALKRQSLGVWVILFLALFTFLAYLLKTEYWRDVEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLA0</accession>
    <name>A0A0S2DLA0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase</fullName>
            <ecNumber evidence="3">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLE_3743</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948515.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3743"/>
    <dbReference type="EnsemblBacteria" id="ALN59087">
        <property type="protein sequence ID" value="ALN59087"/>
        <property type="gene ID" value="GLE_3743"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3743"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3687"/>
    <dbReference type="OMA" id="FYGIGMT"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
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        <source>
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    <sequence length="900" mass="99960" checksum="226B123FCDDE33CD" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLF7</accession>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF04536"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN59265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="302" mass="30167" checksum="1D6EC0CC85170A79" modified="2016-02-17" version="1">MVSLGAMVGPNLRRALLALGLCLLAATAFAQQLAPIPPLDSPVVDTTGTLDATARAQLDAQARALQQRKGSQLQVLMVATTRPEEIEQYAVRAFEQFKLGRKGVDDGVLVVVAKDDRRVRIEVGYGLEGAITDAQSGRIIQEYLGPKFRTGDYAGGLIDATAMLARLIDGEPLPEPMGAGGQGAQGGGDGGGNWVMVLVLAMIGSALVRGVLGGAPALLRALIGGAGAGAVAWLLSMSWGLVALAVAAGFFFSLFGRGGGHYVSSGGWGGYGGGWGGGGGGGGGGWSGGGGSSGGGGASGSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLV6</accession>
    <name>A0A0S2DLV6_LYSEN</name>
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        <submittedName>
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        <submittedName>
            <fullName evidence="3">Response regulator receiver domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_19385</name>
        <name evidence="3" type="ORF">GLE_3951</name>
    </gene>
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        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_3951"/>
    <dbReference type="EnsemblBacteria" id="ALN59293">
        <property type="protein sequence ID" value="ALN59293"/>
        <property type="gene ID" value="GLE_3951"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="2"/>
            <end position="120"/>
        </location>
    </feature>
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        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="122" mass="13330" checksum="EDDD2B42BBE193B9" modified="2016-02-17" version="1">MKLLIVDDSNVIRQRIARLAGDARLPNLEIVGQARNGAEALSLFVRHRPDVVTMDLTMPELGGVECTEQIVAIDDNVNILVVSALSDKSTAITALKKGARGFLYKPFTEDQLVEALLEMLPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM43</accession>
    <name>A0A0S2DM43_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PilT/PilU family type 4a pilus ATPase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Type IV pili twitching motility protein PilT</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Type IV pilus assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pilU</name>
        <name evidence="4" type="ORF">BV903_04490</name>
        <name evidence="5" type="ORF">FE772_20835</name>
        <name evidence="3" type="ORF">GLE_4255</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000008">
        <property type="protein sequence ID" value="OPD65183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948907.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000008.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4255"/>
    <dbReference type="EnsemblBacteria" id="ALN59596">
        <property type="protein sequence ID" value="ALN59596"/>
        <property type="gene ID" value="GLE_4255"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65183">
        <property type="protein sequence ID" value="OPD65183"/>
        <property type="gene ID" value="BV903_04490"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4255"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4195"/>
    <dbReference type="OMA" id="RGQVHEI"/>
    <dbReference type="OrthoDB" id="473670at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006321">
        <property type="entry name" value="PilT/PilU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01420">
        <property type="entry name" value="pilT_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="122"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD65183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW27721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="371" mass="41053" checksum="ABB73D81C61FA2B4" modified="2016-02-17" version="1">MDIGYFLKLMTEKNASDMFLTTGAPVYIKVEGRLYPLGNTGLPPGMVKKIAYSLMDEGQVPQFERDLELNMALALPDAGRFRINVFKQRGEVGMVIRAIRSVIPSIEELQLPQVLKSIIMAPRGLVLIVGSTGSGKSTTLASMIDHRNSNTAGHILTIEDPIEYLHKHKKSIVNQREVGLDTHAFHNALKNAMREAPDVILIGEILDATTMEAAIAFAETGHLCLATLHSNNADQTLERILNFFPEAAHKNVLMNLALNLKAVVSQRLVVGTDGRRIPAAEVLINTPHIRDLMRRGQVHEIKQAMEESLEDGMESFDQCLFRLYKEGRIEMEEALKAADSRDGLALKFRLSEGGTGEHDPYADMYDASAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM70</accession>
    <name>A0A0S2DM70_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyco_trans_2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4171</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948846.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4171"/>
    <dbReference type="EnsemblBacteria" id="ALN59513">
        <property type="protein sequence ID" value="ALN59513"/>
        <property type="gene ID" value="GLE_4171"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4171"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4113"/>
    <dbReference type="OMA" id="ATATPWC"/>
    <dbReference type="OrthoDB" id="957193at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="7"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="279" mass="29950" checksum="4C6D061171532973" modified="2016-02-17" version="1">MSDLPIVVVPVGVDDDALDACLAALDACTPPGARVWLADDAQSGPRGYAIVERWLRSTRLRADYSRRQRGIGEVAHLDEILKACGDSDVAVLAADAVPAPGWLSRLQASFAADGAIATATPWCNAGEAAAWPRIGEIEPMPDAGDAERLARALAQMPAAHPELPAAVGHAVLLRGGARRRAGGLDAESYGSWYAALTDLSLRLSGLGWRNVLCDTAFVARAGEGRPHDGDMDALAARWPDWHSRLAHFLMQDPLRDLRQRLADRLSEVGPPDMQRDLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM84</accession>
    <name>A0A0S2DM84_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD(P)H-dependent oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">NADPH-dependent fmn reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_21345</name>
        <name evidence="2" type="ORF">GLE_4369</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948997.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4369"/>
    <dbReference type="EnsemblBacteria" id="ALN59710">
        <property type="protein sequence ID" value="ALN59710"/>
        <property type="gene ID" value="GLE_4369"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4369"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4308"/>
    <dbReference type="OMA" id="EEYFWRP"/>
    <dbReference type="OrthoDB" id="1818437at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_red" evidence="1">
        <location>
            <begin position="6"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="195" mass="21663" checksum="D338A07A3C7E12A9" modified="2016-02-17" version="1">MASNLRLALVYGSAREGRFCDVVGEWAQRRIARHGGFDVDRIDPVEWPLSGRPSRADEAQLQQLRQRLHAADAFVVVTPEYNHGYPAALKALIDACYEPWRAKPVAFVSYGASSGGLRAIEQLRQVFGELHAATLRDGVCLAHAWRQFGPDGELREPQAAHAAMDTALARLRWWALALRNARETMPYELATEAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMC1</accession>
    <name>A0A0S2DMC1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_4505</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:10137"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:82620"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4505"/>
    <dbReference type="EnsemblBacteria" id="ALN59846">
        <property type="protein sequence ID" value="ALN59846"/>
        <property type="gene ID" value="GLE_4505"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4505"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4441"/>
    <dbReference type="OMA" id="HTIFEED"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="158" mass="18333" checksum="7415715648E8A0DD" modified="2016-02-17" version="1">MKEDRPKTKEKREKNWKLLYLRSEKLARARQLGIDYPNPSSRPEIEDNEPLNLLFICSRNQWRSPTAEAVWRNHPDLRSRSAGTSPNARRRVSADDIRWADAIFVMENKHRSRLQAEFGRVVANTPVHVLDIPDEYQYMDPELVDLLKASVGSILGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNA0</accession>
    <name>A0A0S2DNA0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Flagellar L-ring protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Basal body L-ring protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 11" type="primary">flgH</name>
        <name evidence="12" type="ORF">FE772_22585</name>
        <name evidence="11" type="ORF">GLE_4632</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 9">The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell outer membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the FlgH family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW28015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949198.1">
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_4632"/>
    <dbReference type="EnsemblBacteria" id="ALN59973">
        <property type="protein sequence ID" value="ALN59973"/>
        <property type="gene ID" value="GLE_4632"/>
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    <dbReference type="KEGG" id="lez:GLE_4632"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4568"/>
    <dbReference type="OMA" id="ITQQPMT"/>
    <dbReference type="OrthoDB" id="1900876at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="F:cytoskeletal motor activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00415">
        <property type="entry name" value="FlgH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000527">
        <property type="entry name" value="Flag_Lring"/>
    </dbReference>
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        <property type="entry name" value="PTHR34933"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02107">
        <property type="entry name" value="FlgH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01008">
        <property type="entry name" value="FLGLRINGFLGH"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="9" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="11" id="KW-0966">Cell projection</keyword>
    <keyword evidence="11" id="KW-0969">Cilium</keyword>
    <keyword evidence="11" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242693" description="Flagellar L-ring protein" evidence="10">
        <location>
            <begin position="29"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN59973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW28015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="199" mass="21278" checksum="7CF0B68AEB7F3D8D" modified="2016-02-17" version="1">MNRRNRTPLAGALLVLSIAAPFAGIAAAADLYREESFQPLTSDRRAQRVGDLVTILVYENSSARNTADTTTKTDVGIGGNIKTLGDTSSDFSVGLGDRYGGRGQIQRSGNLLAQISATVTGTFPNGDLAISGEQRININGEKTQIRLTGKVRPNDIGQNNTVLSSRIADARIDYTGDGYVSDRTKPGLIPRILGWLGLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNL2</accession>
    <name>A0A0S2DNL2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4974</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057950329.1">
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_4974"/>
    <dbReference type="EnsemblBacteria" id="ALN60315">
        <property type="protein sequence ID" value="ALN60315"/>
        <property type="gene ID" value="GLE_4974"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4974"/>
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    <dbReference type="OMA" id="QGQPQAW"/>
    <dbReference type="OrthoDB" id="1933827at2"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
    <dbReference type="InterPro" id="IPR004564">
        <property type="entry name" value="OM_lipoprot_carrier_LolA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19574">
        <property type="entry name" value="LolA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595327" evidence="1">
        <location>
            <begin position="20"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="229" mass="24506" checksum="E0D5B5B47094332D" modified="2016-02-17" version="1">MLALLLAATWPLAAPAEQAAAPARVADEGAQPADAAWILPRLAQPVPARTDFVEVRGSALLKAPLRVSGEYRRPDPATLVREVREPYPETTTIRTGAKPGQGEVSIARAGKPPRRFSLSRAPELVALQASFGALLGGDRAELERHYALDAQGTRKQWIVAMKPRDPQVAARVREIVLLGRDDELRCIETRPARGSEQQRTLLGSAARAAAGIADAGQLAALCRSHGPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNP0</accession>
    <name>A0A0S2DNP0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    <organism evidence="2 3">
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        <lineage>
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            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60210">
        <property type="protein sequence ID" value="ALN60210"/>
        <property type="gene ID" value="GLE_4869"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4869"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4800"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="39" mass="4151" checksum="5FF5C1BE4C73CAE2" modified="2016-02-17" version="1">MISLNALNQLGSMQVAPSRANETAAPTNYAEVAMGRDRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNQ6</accession>
    <name>A0A0S2DNQ6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase, families S8 and S53</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_4829</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60170">
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        <property type="gene ID" value="GLE_4829"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4829"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4760"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
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        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
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    </dbReference>
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    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase_S8" evidence="5">
        <location>
            <begin position="651"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN60170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="882" mass="91870" checksum="12E3CB97B6631979" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNS5</accession>
    <name>A0A0S2DNS5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DMT family transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Integral membrane protein DUF6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_22805</name>
        <name evidence="3" type="ORF">GLE_4684</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949235.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4684"/>
    <dbReference type="EnsemblBacteria" id="ALN60025">
        <property type="protein sequence ID" value="ALN60025"/>
        <property type="gene ID" value="GLE_4684"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4684"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4619"/>
    <dbReference type="OMA" id="IGWLVMS"/>
    <dbReference type="OrthoDB" id="1515911at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="18"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="162"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="306" mass="32912" checksum="542320A9653A6DDE" modified="2016-02-17" version="1">MSTVAATAPSADSRTALIQLLIAELLIGSVGVFVHESGQDAITAVLFRCVFGVVFLLAWGWARGLFRGLLGERALIRSAVFSGVLLVLNWVALFAGMQRSSIGVATMVYHFFPFVVLGLAAAFYGERSRAADIGWTAIAFVGVLCSADPFKLLRSADSGYLIGVGLTFVAAVLCGASLLLSRRISRERPFAVVLIQCLVGVVMLAPFADYAKVMLPGAHWFWLAGLGLIHSGVCYVLFYSSYPRLQVATIAVLAFIYPVVALLLDYAVYGHTLAPVQSLGVALIVLGTLGVNLKWRWRLRTQPARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP74</accession>
    <name>A0A0S2DP74_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60471">
        <property type="protein sequence ID" value="ALN60471"/>
        <property type="gene ID" value="GLE_5130"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5130"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5055"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="40" mass="4396" checksum="40A0A93A05423320" modified="2016-02-17" version="1">MSRVGRILPERADGTHVVLRGLCRSGHNLAPFFPALRSHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP78</accession>
    <name>A0A0S2DP78_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA-binding response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Response regulator receiver domain protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BV903_06675</name>
        <name evidence="8" type="ORF">FE772_23795</name>
        <name evidence="6" type="ORF">GLE_4902</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">C3</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000012">
        <property type="protein sequence ID" value="OPD64713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949402.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000012.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4902"/>
    <dbReference type="EnsemblBacteria" id="ALN60243">
        <property type="protein sequence ID" value="ALN60243"/>
        <property type="gene ID" value="GLE_4902"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64713">
        <property type="protein sequence ID" value="OPD64713"/>
        <property type="gene ID" value="BV903_06675"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4902"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4833"/>
    <dbReference type="OMA" id="ALRTHVY"/>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="2"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="126"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="126"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN60243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD64713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW28220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="233" mass="25778" checksum="87DB0479F82BCAE5" modified="2016-02-17" version="1">MRLLVVEDNRNLVANLFDYFEARGYTLDAAPDGPTGLHLAVTQRYDAIVLDWMLPRLDGREVLRSLREEAGSDVPVLMLTARDELPDKIAGFRAGADDYLTKPFALPELEVRLEALAARAAGRGRSKLLQVADLKLDLTTLEVSRGGRSLHLYPACRKLLEVLLQSSPGAVTRERLEHALWGDSPPDGDMLRSHIYELRRAVDGPYPVKLIQTLPRVGYRLAVPADAEADGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP92</accession>
    <name>A0A0S2DP92_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Flagellar basal-body rod protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">flgC</name>
        <name evidence="3" type="ORF">GLE_4635</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949200.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4635"/>
    <dbReference type="EnsemblBacteria" id="ALN59976">
        <property type="protein sequence ID" value="ALN59976"/>
        <property type="gene ID" value="GLE_4635"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4635"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4571"/>
    <dbReference type="OMA" id="YEANLRM"/>
    <dbReference type="OrthoDB" id="1870921at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bbr_C" evidence="2">
        <location>
            <begin position="103"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="153" mass="15968" checksum="5C4CAB74FE4A3509" modified="2016-02-17" version="1">MSDTLFAIARSGMDVERLRMEVIAQNLANASSARGAGVEGYQPVRLVSGPNTASGFEQALGDAARGYTVHAPGALAGARSYGVQATAAPPRIVHEPANPLADADGNVAYPGVDHAGEMALMVQTQRVYEANVVMYNSARSMFMRAMDIGGNSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPH9</accession>
    <name>A0A0S2DPH9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5294</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949697.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60635">
        <property type="protein sequence ID" value="ALN60635"/>
        <property type="gene ID" value="GLE_5294"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5294"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5212"/>
    <dbReference type="OrthoDB" id="2002071at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595934" evidence="1">
        <location>
            <begin position="38"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="181" mass="17314" checksum="756645C228210B0B" modified="2016-02-17" version="1">MYPSVPRVAAIRAARRHRHASALAALVLAAALPGVRAAGPGADPTPGADTTVVIARTVHPRIAYRALPAQDNPVRTEATTFPGQVFHATLSRSLAPLDDAALGQHGSGGLGVAAAADAASAMLVPAAATGAGATFAGPGASAPLGASASVGGAVVGATAGLGDTLTGAVMQALAPPPGSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPK6</accession>
    <name>A0A0S2DPK6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_25115</name>
        <name evidence="1" type="ORF">GLE_5185</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949617.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5185"/>
    <dbReference type="EnsemblBacteria" id="ALN60526">
        <property type="protein sequence ID" value="ALN60526"/>
        <property type="gene ID" value="GLE_5185"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5185"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5105"/>
    <dbReference type="OMA" id="PETAMNQ"/>
    <dbReference type="OrthoDB" id="1869306at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="196" mass="21178" checksum="3272E49613CF0E85" modified="2016-02-17" version="1">MTTQTDPIPGAAGPDPAALAAKFQRNPAPKRAYRVLLKVAQAPGPLANVRGFAQYEAPDCVYIPDPVAGVPTHPMKALDLEFSRVDDTTYAATVYADAMLDEDYLGKGVCHWQVASVNAQLKASGEQAETSFVSNLLGSEVQGQQERTKYYAKAHYPRSETVSDFPDAGAADPARFQPELRNELFTITMTAKEGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPR2</accession>
    <name>A0A0S2DPR2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">N-acetylglucosamine-6-phosphate deacetylase</fullName>
            <ecNumber evidence="8">3.5.1.25</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">nagA</name>
        <name evidence="9" type="ORF">FE772_25170</name>
        <name evidence="8" type="ORF">GLE_5197</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="6">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the metallo-dependent hydrolases superfamily. NagA family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.25" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949625.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5197"/>
    <dbReference type="EnsemblBacteria" id="ALN60538">
        <property type="protein sequence ID" value="ALN60538"/>
        <property type="gene ID" value="GLE_5197"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5197"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5116"/>
    <dbReference type="OMA" id="HAFNAMP"/>
    <dbReference type="OrthoDB" id="1026967at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047419">
        <property type="term" value="F:N-acetylgalactosamine-6-phosphate deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008448">
        <property type="term" value="F:N-acetylglucosamine-6-phosphate deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00854">
        <property type="entry name" value="NagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003764">
        <property type="entry name" value="GlcNAc_6-P_deAcase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038994">
        <property type="entry name" value="NagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00221">
        <property type="entry name" value="nagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="7">
        <location>
            <begin position="52"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="217"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="305"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="4">
        <location>
            <position position="272"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR038994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN60538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW28453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="377" mass="39416" checksum="618C7AFE5C2CF2EE" modified="2016-02-17" version="1">MTATAFVNGRVLSERGFESDLSVIVEDGWIVAVLPGPAPAGAQAVDLQGRYLAPGFIDTQVNGGGDVLFNDVPTVDGLRTIAEAHRRFGTTGMMPTLISDDVAVMLRAIGAVREAIAAGVPGILGIHLEGPYLAPARKGVHNPDKFHTPGEDELDRIASLDNGKTLLTLAPERFDDATLRALAARGVLLSAGHTAADYDRLRAAFANGVSGVTHLFNAMTPLGSREPGGVGACLDDPNAWCGVIVDGEHVHDASLRIAIAAKPRGKIMLVTDAMPPVGGVNEDFVLYGETMTCRDGKCTTASGTLAGSALDMASAVRNTVQRLGLPLDEACRMASTYPAQFLGLGDRLGKIRPGYRADLVALDDALAVQDSWIGGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ08</accession>
    <name>A0A0S2DQ08_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Oxygen-dependent coproporphyrinogen-III oxidase</fullName>
            <shortName evidence="5">CPO</shortName>
            <shortName evidence="5">Coprogen oxidase</shortName>
            <shortName evidence="5">Coproporphyrinogenase</shortName>
            <ecNumber evidence="5">1.3.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">hemF</name>
        <name evidence="7" type="ORF">FE772_23945</name>
        <name evidence="6" type="ORF">GLE_4939</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>coproporphyrinogen III + 2 H(+) + O2 = 2 CO2 + 2 H2O + protoporphyrinogen IX</text>
            <dbReference type="Rhea" id="RHEA:18257"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="EC" id="1.3.3.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1 5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the aerobic coproporphyrinogen-III oxidase family.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.3" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949428.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4939"/>
    <dbReference type="EnsemblBacteria" id="ALN60280">
        <property type="protein sequence ID" value="ALN60280"/>
        <property type="gene ID" value="GLE_4939"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4939"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4867"/>
    <dbReference type="OMA" id="HDKGTLF"/>
    <dbReference type="OrthoDB" id="1086432at2"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00322"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <location>
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        </location>
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            <end position="275"/>
        </location>
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            <end position="260"/>
        </location>
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            <name>substrate</name>
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        <ligand>
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        <location>
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        <ligand>
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        <ligand>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW28243.1"/>
        </source>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
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    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="303" mass="34521" checksum="9E7A20F060857067" modified="2016-02-17" version="1">MNDFDRVRDYLSGLQDRICAAIETADGGARFVEDQWQRAEGGGGRTRILRGGNVFEQAGIGFSDVSGSKLPPSASAARPELAGASWRAVGVSLVFHPHNPYLPTTHANVRHFRAMRDGETVAWWFGGGFDLTPFYPFAEDVQHWHRTARDLCAPFGGEERYQAHKRWCDEYFFLKHRNETRGVGGLFFDDLHGDFERDFGYMRAVGDGFLDAYLPLVDRRRDTPYGERERQFQLYRRGRYVEFNLVFDRGTLFGLQSGGRTESILMSLPPLVRWEYGFQPEADSDEAKLAQFLSPRDWLGEAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ33</accession>
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        <submittedName>
            <fullName evidence="3">Two-component system sensor protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">GLE_5267</name>
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        <name type="scientific">Lysobacter enzymogenes</name>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN60608.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="407" mass="43489" checksum="AE4B9D6140CA9ED6" modified="2016-02-17" version="1">MPEVTFGAGPVATAARAAQHGRMPMPPPLRTLLQPLNLPAVLSWLGVGLSLPYDRATQGPLVWTVMAVFLFAFLGDELVGTARARRGFWFSLQAITALAICYLAPRGGAAPALLVILVAQLAMSYPLRRVVAMTAALNLALYLILSTAGNRGALIITLCFIGFQGFAVLVAHYARGAEQARDRLALVNADLLATRALLADSARDAERLRMARELHDVAGHKLTAMMLNLRALAAEPDLAERREVQVAQQLAGELLGDIRSVVQALRDARGLDLATALRALAAPLPRPALELDLDDELNLTDPALAETLLRVVQEALTNAARHADAARLRVALHRDGAALELRIADDGRVRAPLREGNGLSGMRERVTAAGGELDFSLSPEGAMRIHARFPLQRPLPGPRAPTAATPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ48</accession>
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        <lineage>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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        <location>
            <begin position="110"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
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            <begin position="182"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="281" mass="32167" checksum="71EDB0013B287566" modified="2016-02-17" version="1">MKLNPFTKKQKNTDPSRYDELCAQFVEAEVRFAASKAALEKAQADYDAKFKAFHTLEAKSQSTFWSTQEQTLHREMNRAQHHQQECQSAHRTIEREFNKLRSRIEAPNQLSKSKAQLAQLEKQHGDLRNELAKAQARQNQLQTRADQLAQDVENDQRLAAQALIDSDDEAPEIALPKGQAELHVVRAALEQIGKRIEELQTQLNEMPKRLRDALRSVYCNQATHAETELEEALPGFVGHIARYKVAQYRAGWTSSTQRHEIDIPDNAWEAANTRLDAEMRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ81</accession>
    <name>A0A0S2DQ81_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type III secretion apparatus protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">sctL</name>
        <name evidence="5" type="ORF">BV903_11085</name>
        <name evidence="6" type="ORF">FE772_24745</name>
        <name evidence="4" type="ORF">GLE_5106</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">C3</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000026">
        <property type="protein sequence ID" value="OPD63846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW28381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_MTAY01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5106"/>
    <dbReference type="EnsemblBacteria" id="ALN60447">
        <property type="protein sequence ID" value="ALN60447"/>
        <property type="gene ID" value="GLE_5106"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD63846"/>
        <property type="gene ID" value="BV903_11085"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5106"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5031"/>
    <dbReference type="OrthoDB" id="1274035at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018035">
        <property type="entry name" value="Flagellar_FliH/T3SS_HrpE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02108">
        <property type="entry name" value="FliH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FliH" evidence="3">
        <location>
            <begin position="100"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="67"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD63846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW28381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="245" mass="26000" checksum="B16AC8D3135B5806" modified="2016-02-17" version="1">MPADPLRHEAPSAAGASNVADLTARRDLGRAAGTVAVFERKQFERALAGTVVPAQQWSQVVEMDQTLARVNALYDQAGDEIQQAREAGYAAGFAEGLARAQQQMAQQLADLNERRARVLADAGSRVTELACAIVARISPEFDARAVVPPLVMQAVEAAQAEQFLLIRVHPSVREEVAQGLGLVRQAHPVVGVIELVDDESLDKLSCVVVSEVGEVRAGVAQQIEAIRIALSGAEYGAEHGAEHGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ85</accession>
    <name>A0A0S2DQ85_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5341</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60682">
        <property type="protein sequence ID" value="ALN60682"/>
        <property type="gene ID" value="GLE_5341"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5341"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="50" mass="5210" checksum="5A70A97F543E89F5" modified="2016-02-17" version="1">MLEDAVEIGTRAYPRGAREAGRIHCRRAAARCGIIRAGAGNDRDAAAGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQC8</accession>
    <name>A0A0S2DQC8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein TonB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLE_5350</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cell inner membrane</location>
            <topology evidence="1 9">Single-pass membrane protein</topology>
            <orientation evidence="1 9">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TonB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949742.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5350"/>
    <dbReference type="EnsemblBacteria" id="ALN60691">
        <property type="protein sequence ID" value="ALN60691"/>
        <property type="gene ID" value="GLE_5350"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5350"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5266"/>
    <dbReference type="OMA" id="DNAMEYY"/>
    <dbReference type="OrthoDB" id="2074833at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031992">
        <property type="term" value="F:energy transducer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015343">
        <property type="term" value="F:siderophore transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003538">
        <property type="entry name" value="TonB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01374">
        <property type="entry name" value="TONBPROTEIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="TonB_C" evidence="11">
        <location>
            <begin position="271"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="213"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN60691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="346" mass="36539" checksum="247C7D55EB72336B" modified="2016-02-17" version="1">MIANNDRHYSRLSAVKQVSAVFALGCALAACGKKEDAAPAAPEQAAPNAAAPAASANNAVSAKVSALSVEQLREAARKAYAENRLYAPVEDNAVEYYLALREKAPADAVASSALTDLLPMTVIATEQSIGREDFSEAQRLSALIERADPQHPALARLKASIGAAQQAVTKRAEQEKLTAEEQARKQAELEKQRLAQQQQQQQQAAQQLATQQAAERQAATQRAAEQRAAEQRAAEQRAAAPAAAPERPAPAPAAPSAPAAAPSELRAVSTPAPRYPPDALRAGTSGEVQVEFTVGTDGSVTAARVVRANPPRVFDREAVNAVRKWRFQPVAAPVTTRRTIGFNPGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQS5</accession>
    <name>A0A0S2DQS5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF3489 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_00780</name>
        <name evidence="2" type="ORF">GLE_5517</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949856.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5517"/>
    <dbReference type="EnsemblBacteria" id="ALN60858">
        <property type="protein sequence ID" value="ALN60858"/>
        <property type="gene ID" value="GLE_5517"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5517"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5431"/>
    <dbReference type="OMA" id="PIWRETG"/>
    <dbReference type="OrthoDB" id="2044781at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021880">
        <property type="entry name" value="DUF3489"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11994">
        <property type="entry name" value="DUF3489"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="208" mass="21467" checksum="0FCA91D446D7DFCB" modified="2016-02-17" version="1">MSNIELSTNQRTVLELAVATEGRIERYPAGLLGGARTSVVRGLLRNGFVEQHDAGYRLTADGYAAAGAEAPAGDDPDSAGGSDSEAPNESASDTDTGLTDGAATAPADSAATAATPPVKPKRAARGDTKIAKVVDLLVRPQGATIAQIMAETEWQQHSVRGFLAGTVKKKGYTVTSSKEGDGDRVYRIATEKAKVRSGAAAAHGDEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2003-10-01" modified="2022-08-03" version="104" xmlns="http://uniprot.org/uniprot">
    <accession>Q7WZ08</accession>
    <name>Q7WZ08_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">S-adenosylmethionine decarboxylase proenzyme</fullName>
            <shortName evidence="10">AdoMetDC</shortName>
            <shortName evidence="10">SAMDC</shortName>
            <ecNumber evidence="10">4.1.1.50</ecNumber>
        </recommendedName>
        <component>
            <recommendedName>
                <fullName evidence="10">S-adenosylmethionine decarboxylase beta chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="10">S-adenosylmethionine decarboxylase alpha chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="10 11" type="primary">speD</name>
        <name evidence="15" type="ORF">BV903_04535</name>
        <name evidence="17" type="ORF">D9T17_07505</name>
        <name evidence="16" type="ORF">FE772_20885</name>
        <name evidence="13" type="ORF">GLE_4264</name>
        <name evidence="14" type="ORF">LEN_0939</name>
        <name evidence="18" type="ORF">SAMN05421681_101450</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2005" name="Appl. Environ. Microbiol." volume="71" first="261" last="269">
            <title>A clp gene homologue belonging to the Crp gene family globally regulates lytic enzyme production, antimicrobial activity, and biological control activity expressed by Lysobacter enzymogenes strain C3.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
                <person name="Reedy R.M."/>
                <person name="Palumbo J.D."/>
                <person name="Zhou J.M."/>
                <person name="Yuen G.Y."/>
            </authorList>
            <dbReference type="PubMed" id="15640196"/>
            <dbReference type="DOI" id="10.1128/AEM.71.1.261-269.2005"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">C3</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2006-11" db="EMBL/GenBank/DDBJ databases">
            <title>Cloning and functional characterization of speD gene in Lysobacter enzymogenes strain OH11.</title>
            <authorList>
                <person name="Zhu H."/>
                <person name="Hu B."/>
                <person name="Liu F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">OH11</strain>
        </source>
    </reference>
    <reference evidence="13 19" key="3">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 19">C3</strain>
        </source>
    </reference>
    <reference evidence="22" key="4">
        <citation type="journal article" date="2016" name="DNA Res." volume="0" first="0" last="0">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer, Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22">M497-1</strain>
        </source>
    </reference>
    <reference evidence="18 20" key="5">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 20">ATCC 29487</strain>
        </source>
    </reference>
    <reference evidence="14 22" key="6">
        <citation type="journal article" date="2017" name="DNA Res." volume="24" first="169" last="177">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
            <dbReference type="PubMed" id="28065880"/>
            <dbReference type="DOI" id=".1093/dnares/dsw055"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 22">M497-1</strain>
        </source>
    </reference>
    <reference evidence="15 21" key="7">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 21">B25</strain>
        </source>
    </reference>
    <reference evidence="17 23" key="8">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 23">OH11</strain>
        </source>
    </reference>
    <reference evidence="16 24" key="9">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 24">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>H(+) + S-adenosyl-L-methionine = CO2 + S-adenosyl 3-(methylsulfanyl)propylamine</text>
            <dbReference type="Rhea" id="RHEA:15981"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57443"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="4.1.1.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
        <text evidence="10">Binds 1 pyruvoyl group covalently per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Amine and polyamine biosynthesis; S-adenosylmethioninamine biosynthesis; S-adenosylmethioninamine from S-adenosyl-L-methionine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.</text>
    </comment>
    <comment type="PTM">
        <text evidence="10">Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.50" evidence="10"/>
    <dbReference type="EMBL" id="AH013001">
        <property type="protein sequence ID" value="AAP83140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="EF116940">
        <property type="protein sequence ID" value="ABL14107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP014940">
        <property type="protein sequence ID" value="BAV96426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000008">
        <property type="protein sequence ID" value="OPD65190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000019">
        <property type="protein sequence ID" value="ROU08032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNOG01000001">
        <property type="protein sequence ID" value="SDW22405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948915.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4264"/>
    <dbReference type="EnsemblBacteria" id="ALN59605">
        <property type="protein sequence ID" value="ALN59605"/>
        <property type="gene ID" value="GLE_4264"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAV96426">
        <property type="protein sequence ID" value="BAV96426"/>
        <property type="gene ID" value="LEN_0939"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65190">
        <property type="protein sequence ID" value="OPD65190"/>
        <property type="gene ID" value="BV903_04535"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDW22405">
        <property type="protein sequence ID" value="SDW22405"/>
        <property type="gene ID" value="SAMN05421681_101450"/>
    </dbReference>
    <dbReference type="KEGG" id="lem:LEN_0939"/>
    <dbReference type="KEGG" id="lez:GLE_4264"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4203"/>
    <dbReference type="OMA" id="HVTVHTY"/>
    <dbReference type="OrthoDB" id="757383at2"/>
    <dbReference type="UniPathway" id="UPA00331">
        <property type="reaction ID" value="UER00451"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000183696">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000218824">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004014">
        <property type="term" value="F:adenosylmethionine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006557">
        <property type="term" value="P:S-adenosylmethioninamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00465">
        <property type="entry name" value="AdoMetDC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003826">
        <property type="entry name" value="AdoMetDC_fam_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009165">
        <property type="entry name" value="S-AdoMet_deCO2ase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016067">
        <property type="entry name" value="S-AdoMet_deCO2ase_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33866">
        <property type="entry name" value="PTHR33866"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02675">
        <property type="entry name" value="AdoMet_dc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001356">
        <property type="entry name" value="SAM_decarboxylas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56276">
        <property type="entry name" value="SSF56276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03331">
        <property type="entry name" value="SAM_DCase_Eco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="2 10" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="7 10 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 10" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="8 10" id="KW-0704">Schiff base</keyword>
    <keyword evidence="4 10" id="KW-0745">Spermidine biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0865">Zymogen</keyword>
    <feature type="chain" id="PRO_5035345178" description="S-adenosylmethionine decarboxylase beta chain" evidence="10">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035345177" description="S-adenosylmethionine decarboxylase alpha chain" evidence="10">
        <location>
            <begin position="113"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via pyruvic acid" evidence="10">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for processing activity" evidence="10">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for catalytic activity" evidence="10">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage (non-hydrolytic); by autolysis" evidence="10">
        <location>
            <begin position="112"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="modified residue" description="Pyruvic acid (Ser); by autocatalysis" evidence="10">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="AAP83140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ABL14107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN59605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="BAV96426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OPD65190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QCW27730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ROU08032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="SDW22405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000183696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000218824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="264" mass="30595" checksum="5D28C7061A412C53" modified="2003-10-01" version="1">MVKPLPRLRLQGFNNLTKALSFNIYDVCFAASEDERRRYIEYIDEAYNADRLTQILTDVAEIIGANILNIARQDYDPQGASVTILISEEPVIDKKDAGKEIISDAVVAHMDKSHITVHTYPETHPDNGIATFRADIDVATCGVISPLKALNYLIESFESDIVVMDYRVRGFTRDIKGRKHYIDHKINSIQDYLAKNIKSRYEMIDVNVYQENIFHSKMHLKEFDLDTYLFEEKAKNLSFKERMKIEARLKREIEELYHGRNLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA72</accession>
    <name>A0A0S2DA72_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_01295</name>
        <name evidence="3" type="ORF">GLE_0076</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55435">
        <property type="protein sequence ID" value="ALN55435"/>
        <property type="gene ID" value="GLE_0076"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0076"/>
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    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242123" evidence="2">
        <location>
            <begin position="21"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="78" mass="8304" checksum="B1E92B0601514315" modified="2016-02-17" version="1">MQIAPALAIAVLAAALSACGGVSYRDTNAAVDARPECASGPKRPGETPPTWCERKVQTEWKSDGGGEKVDFKKKDDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAI2</accession>
    <name>A0A0S2DAI2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3-beta hydroxysteroid dehydrogenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">NAD(P)H steroid dehydrogenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">NAD-dependent epimerase/dehydratase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_21250</name>
        <name evidence="4" type="ORF">FE772_01880</name>
        <name evidence="2" type="ORF">GLE_0204</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
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    <dbReference type="STRING" id="69.GLE_0204"/>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61925">
        <property type="protein sequence ID" value="OPD61925"/>
        <property type="gene ID" value="BV903_21250"/>
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    <dbReference type="KEGG" id="lez:GLE_0204"/>
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    </dbReference>
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    </dbReference>
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            <end position="244"/>
        </location>
    </feature>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55563.1"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="328" mass="34749" checksum="06E1F289A2877782" modified="2016-02-17" version="1">MKILVTGGGGFLGQALCRGLVARGHEVVSFNRGHYPALEPLGVTQIQGDLADRDAVIAAARGCGAIFHNAAKAGAWGSYESYHQANVVGTQNVLAACQAHGIGQLVYTSTPSVTHRATHPVEGGSAETVPYGEGFKAAYATTKTIAEKAVLAANSPQLATVALRPRLIWGVGDNQLLPRLVQRANAGRLRFVGTGENRIDTTYIDNAAQAHFDAFDHLAPGAACAGKAYFISNGDPRTVRETLNGLLGAVGAPTVDKTLPFRAAYVIGAICEGLWTVLPLKGEPPMTRFLAEQLSTTHWYDMGPARRDFGYVPRVSFDEGLARIKAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAM8</accession>
    <name>A0A0S2DAM8_LYSEN</name>
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        <submittedName>
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        </submittedName>
        <submittedName>
            <fullName evidence="2">Hydrolase, alpha/beta hydrolase fold family protein</fullName>
        </submittedName>
    </protein>
    <gene>
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        <name type="scientific">Lysobacter enzymogenes</name>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55591">
        <property type="protein sequence ID" value="ALN55591"/>
        <property type="gene ID" value="GLE_0232"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0232"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.234"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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            <begin position="35"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="293" mass="32373" checksum="364DFB862A1965AF" modified="2016-02-17" version="1">MDGSSRDPAPFARGHVDTPSGRIAYRERGDGPVALFVHGVLLNGHLWRHQLRHLSDLRRCIAVDLLAHGDTDSGAGQDVSVTANAHMLAQFLDALDIERVDLVGNDSGGGIAQIFAALYPQRVRSLTLTDCDAHDNWPPQAFEPFLAMAAGGGLGATLQAMVDDKAVYRSAQALGPAYQQPQALGDEDIDAYLRPLLRSPQRLADLQRFLAGFDPVHTVRIEAQLRQLRAPTLIAWGDDDVYFDARWSQWLAEAIPGTRRRVVLEGARIFFPEERWAEFNLLLREHWLAAADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAX3</accession>
    <name>A0A0S2DAX3_LYSEN</name>
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        <submittedName>
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    </protein>
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        <name evidence="10" type="ORF">FE772_02450</name>
        <name evidence="9" type="ORF">GLE_0328</name>
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        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
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            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="QCW24701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_0328"/>
    <dbReference type="EnsemblBacteria" id="ALN55686">
        <property type="protein sequence ID" value="ALN55686"/>
        <property type="gene ID" value="GLE_0328"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0328"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.325"/>
    <dbReference type="OMA" id="DNFTDPC"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010916">
        <property type="entry name" value="TonB_box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00430">
        <property type="entry name" value="TONB_DEPENDENT_REC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0798">TonB box</keyword>
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        <location>
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            <end position="27"/>
        </location>
    </feature>
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            <end position="971"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="55"/>
            <end position="180"/>
        </location>
    </feature>
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        <location>
            <begin position="385"/>
            <end position="969"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN55686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW24701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="971" mass="104968" checksum="3A8787044B666047" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB82</accession>
    <name>A0A0S2DB82_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_02825</name>
        <name evidence="2" type="ORF">GLE_0406</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946012.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55764">
        <property type="protein sequence ID" value="ALN55764"/>
        <property type="gene ID" value="GLE_0406"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0406"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.403"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242169" evidence="1">
        <location>
            <begin position="34"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="78" mass="8432" checksum="C407A9C735F9FA24" modified="2016-02-17" version="1">MKISTPERRNRSSRLSLVAMLAFAFAASFSATAVEPDCEDCKITYLVCLRNAPPLGHLVCSIQYSQCLAAHNCPASSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBB1</accession>
    <name>A0A0S2DBB1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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        <name evidence="4" type="ORF">FE772_03140</name>
        <name evidence="2" type="ORF">GLE_0478</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000113">
        <property type="protein sequence ID" value="OPD61115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946065.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000113.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55836">
        <property type="protein sequence ID" value="ALN55836"/>
        <property type="gene ID" value="GLE_0478"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61115">
        <property type="protein sequence ID" value="OPD61115"/>
        <property type="gene ID" value="BV903_25325"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0478"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.475"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594916" evidence="1">
        <location>
            <begin position="39"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="167" mass="17325" checksum="2D7892993B8C5228" modified="2016-02-17" version="1">MKTTHAAPAPKRDTAAALRRYAACGLALAALMPALASAYGTCNAYINADGTVQAVRGEGDCWIGWPTRIATGVYTVGVSYPLMDDTDPATGAPIRTFHPGICTISAGSEHAGAASVKMVPDFKPPMSPQPVPSTHNGRVTYTVRTFAAGTGPTLVPADLDFSMLCIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBN6</accession>
    <name>A0A0S2DBN6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase, group 2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0589</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55947">
        <property type="protein sequence ID" value="ALN55947"/>
        <property type="gene ID" value="GLE_0589"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0589"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="269"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="304"/>
            <end position="324"/>
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    </feature>
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        <location>
            <begin position="42"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="350" mass="38038" checksum="2A68A8E48829A8BD" modified="2016-02-17" version="1">MNARRSLRAEGPVFAGGPLRPNAVPARDARYARKPIKVVIQLPCRDEAEQLPATLAALPRRLPGVDEVEWLVIDDGSSDDTADVAIAHGAHAVLRLPHNRGLARAFCAGLEAACRRGADVIVNVDGDNQYDAAAIPELVARVLAGRADIVVGCRPIERIAHFPWWKKRLQRLGSAVVRAAASVRVDDATSGFRAYSRDAAMRLNVYSSYTYTLETLIQAGQSGLRVEGLPVGVNPPTRPSRLIRSVPQYLGRSMLTIVRSFLTYRPLEFFLVPSGLCMSLGALIGARFLYAFAQGDGDGHVQSLILSALLIVVGTVGAAVGLLANQMVVNRRLLEEQQQSRRRAEWRPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBP6</accession>
    <name>A0A0S2DBP6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_15535</name>
        <name evidence="4" type="ORF">FE772_03610</name>
        <name evidence="2" type="ORF">GLE_0582</name>
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    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000040">
        <property type="protein sequence ID" value="OPD63044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946141.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55940">
        <property type="protein sequence ID" value="ALN55940"/>
        <property type="gene ID" value="GLE_0582"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD63044"/>
        <property type="gene ID" value="BV903_15535"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0582"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.575"/>
    <dbReference type="OrthoDB" id="1850719at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="141" mass="15301" checksum="07EC6597A4FF7A1C" modified="2016-02-17" version="1">MLSIIVMGIFGGLCGLGFLAVMALVAKNGKHQFDYVQFDSEQDVYALAQGWAGRNGYALKRSEGGLRVYQKGTGFLTAPMFLEIDRNDGRWSFKSYVRVNGLVVQGDVGLSGDGFLVKVPRSMAKKAQNELYTAAGLAPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBS9</accession>
    <name>A0A0S2DBS9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mucin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_0624</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0624"/>
    <dbReference type="EnsemblBacteria" id="ALN55982">
        <property type="protein sequence ID" value="ALN55982"/>
        <property type="gene ID" value="GLE_0624"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0624"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.615"/>
    <dbReference type="OMA" id="KTWSVNV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="25"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026466">
        <property type="entry name" value="Fim_isopep_form_D2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01345">
        <property type="entry name" value="DUF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04226">
        <property type="entry name" value="RrgB_K2N_iso_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpA-like" evidence="4">
        <location>
            <begin position="3899"/>
            <end position="4001"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="3597"/>
            <end position="3617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Feng T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
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        <source>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <dbReference type="OrthoDB" id="1757088at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="208"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="297" mass="31264" checksum="390594B55A007BDD" modified="2016-02-17" version="1">MSARPVRATPHSGAPLPPALAAWVERSWASARPASAPAWPREHSLPTGSLHLAVRLDGPPLRTYADADDALGRSHPPALLAGARAGYVIKDASRPAASVGAMLRPGAALALFGVSAAELEGGYVGLDELCGAGAADGLYERLAAAADPRSRRRLFEAFLRARLRPVRGLDPQIVRAVRSLQGAAPGGDCAAGADERRVAGWVAASGRSHRRFIAGFRDAAGLSPKRYARVLRFKRLLSALAATPRPDWAQLALDGGYFDQSHLIREFREFAGVSPRAYLAAAAASPHHLPIGGPKPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCK4</accession>
    <name>A0A0S2DCK4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0903</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56261">
        <property type="protein sequence ID" value="ALN56261"/>
        <property type="gene ID" value="GLE_0903"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0903"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="38" mass="3805" checksum="F3FEBA84360A9D2B" modified="2016-02-17" version="1">MHSVLTTGKYNHASPAPAQPGGAGAADRRQEATIGTNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCL7</accession>
    <name>A0A0S2DCL7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BV903_19670</name>
        <name evidence="5" type="ORF">GLE_0892</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000057">
        <property type="protein sequence ID" value="OPD62210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0892"/>
    <dbReference type="EnsemblBacteria" id="ALN56250">
        <property type="protein sequence ID" value="ALN56250"/>
        <property type="gene ID" value="GLE_0892"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62210">
        <property type="protein sequence ID" value="OPD62210"/>
        <property type="gene ID" value="BV903_19670"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0892"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.881"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011017">
        <property type="entry name" value="TRASH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015358">
        <property type="entry name" value="Tscrpt_reg_MerR_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007029">
        <property type="entry name" value="YHS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00376">
        <property type="entry name" value="MerR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09278">
        <property type="entry name" value="MerR-DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04945">
        <property type="entry name" value="YHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00746">
        <property type="entry name" value="TRASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH merR-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD62210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="213" mass="23199" checksum="25D203AD787C393E" modified="2016-02-17" version="1">MKIGEFAQRVGVGIDTVRYYERQGLLPLPMRQLSGYRRFETKDVARLQFVRRAKSLGFTLAEIRELLALLGSRGSDMAGVKAATTQKLADVEAKLAELVHIRDLLQMLLDSCPGRGAVECCPIVNALEGEKHMSGPHPLEKPSDGTTAPQRSCCSAARTCETQDAASAVDPICGMQVNIETTQHHAEQSGVGYYFCSAQCRQQFLESGAPAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD31</accession>
    <name>A0A0S2DD31_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phosphoenolpyruvate carboxykinase [GTP]</fullName>
            <shortName evidence="9">PEP carboxykinase</shortName>
            <shortName evidence="9">PEPCK</shortName>
            <ecNumber evidence="9">4.1.1.32</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">GTP-dependent phosphoenolpyruvate carboxykinase</fullName>
            <shortName evidence="9">GTP-PEPCK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">pckA</name>
        <name evidence="9" type="synonym">pckG</name>
        <name evidence="13" type="ORF">GLE_1099</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>GTP + oxaloacetate = CO2 + GDP + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:10388"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.1.1.32"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="9">Binds 1 Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.32" evidence="9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1099"/>
    <dbReference type="EnsemblBacteria" id="ALN56457">
        <property type="protein sequence ID" value="ALN56457"/>
        <property type="gene ID" value="GLE_1099"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1099"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1086"/>
    <dbReference type="OMA" id="PAGKKHY"/>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004613">
        <property type="term" value="F:phosphoenolpyruvate carboxykinase (GTP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00819">
        <property type="entry name" value="PEPCK_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.449.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00452">
        <property type="entry name" value="PEPCK_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018091">
        <property type="entry name" value="PEP_carboxykin_GTP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008209">
        <property type="entry name" value="PEP_carboxykinase_GTP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035077">
        <property type="entry name" value="PEP_carboxykinase_GTP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035078">
        <property type="entry name" value="PEP_carboxykinase_GTP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
        <property type="entry name" value="PEP_carboxykinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11561">
        <property type="entry name" value="PTHR11561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00821">
        <property type="entry name" value="PEPCK_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17297">
        <property type="entry name" value="PEPCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001348">
        <property type="entry name" value="PEP_carboxykinase_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68923">
        <property type="entry name" value="SSF68923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00505">
        <property type="entry name" value="PEPCK_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2 9" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="6 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 9 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 9" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PEPCK_N" evidence="12">
        <location>
            <begin position="27"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="PEPCK_GTP" evidence="11">
        <location>
            <begin position="240"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="215"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="383"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="224"/>
        </location>
        <ligand>
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        <location>
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        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
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            <position position="266"/>
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        <ligand>
            <name>substrate</name>
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        <location>
            <begin position="267"/>
            <end position="272"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="295"/>
        </location>
        <ligand>
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        </ligand>
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        <location>
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        <ligand>
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        </ligand>
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            <position position="416"/>
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        <ligand>
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        </ligand>
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            <begin position="509"/>
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        <ligand>
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        </ligand>
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            <dbReference type="Pfam" id="PF17297"/>
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        <source>
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    <sequence length="601" mass="65244" checksum="D672E071FE597E55" modified="2016-02-17" version="1"> </sequence>
</entry>
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            <authorList>
                <person name="Kobayashi D.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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            <end position="34"/>
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            <dbReference type="EMBL" id="ALN56527.1"/>
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        <source>
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        <source>
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    <sequence length="301" mass="29516" checksum="8A46661241A5F1D0" modified="2016-02-17" version="1">MADASSGVSGSDSSQNAQNAADRAAETAAAQQAAADKAATEAAAAAALNSVQAAPVDLSISPAAISQLSAMTVDTVPSLSSLQTLGGVPTAATYADIAQATATPTTPAVTEYNAWSAGFSITPNDPATVETTPLSAVSINVGLNHVGDINANLEARMGIAPAQVTFAGAVSYTNGVTTYGLSGLAGPFGGIADPNYGITATTATELDFGKLGLSLNVNANADGFTNGTFGANVTTPLSEGWNGFAGVSVSGDRNGVNAVEGMLGANYNANGASLGVSGSGRVDTRTGDVSGGAKFNLGIKF</sequence>
</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
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        <source>
            <dbReference type="EMBL" id="ALN56408.1"/>
        </source>
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    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="40" mass="4003" checksum="C7E1D5026444FB0B" modified="2016-02-17" version="1">MGGPSGPMRSPYVEGPSVPMPSLYVGGPSGPTLLCRIAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDN8</accession>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="6 8" key="2">
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            <authorList>
                <person name="Feng T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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        <text evidence="1">May be involved in the biogenesis of curli organelles.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CsgG family.</text>
    </comment>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW25498.1"/>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="321" mass="33159" checksum="A0C226D3291BBFF3" modified="2016-02-17" version="1">MKTANRGIQAMACVVGLGVALAAAPGWAQRKSAQDQRAEKMNEIPTCSKNLGAISVIEPEDATNWWTGQQLPAPSKLIKVFVQKSRCFTLVDRGAGMDVAMRERDLAASGQLRNKSNVGKGQIRAADYVLVPDLISKNSNAGGNAVGGLLGGLIGGRAGAVAGNLNFNKRTADVVLTVTDVRSSEQVAMAEGSAKKTDIGFGASGALFGSSGLGGAGVSGYANTEIGQVITMAYLQAYTNLVAELGGLSGNPSASNAQQAVTVVKSARLFANANGSGKVVRPLDPGMMLYPTGNKQGAMWEVEDELGNKGWVTSLALELSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDW7</accession>
    <name>A0A0S2DDW7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">LysR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_07515</name>
        <name evidence="3" type="ORF">GLE_1423</name>
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    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW25533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946765.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1423"/>
    <dbReference type="EnsemblBacteria" id="ALN56780">
        <property type="protein sequence ID" value="ALN56780"/>
        <property type="gene ID" value="GLE_1423"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1423"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1402"/>
    <dbReference type="OMA" id="DYYFACD"/>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12727">
        <property type="entry name" value="PBP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="1">
        <location>
            <begin position="24"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="2">
        <location>
            <begin position="145"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="361" mass="38910" checksum="A2F75080DC09A429" modified="2016-02-17" version="1">MFKVQIQPRWTLHAADGQPLPGKLIELLQGVHATGSLAAACRRAGLSYRYAWGLLQQSQALFGAPLLRMARGRGARLSALGERLVWAEQRIAARLAPTLDSLASEVEVELGRALSAQAAPPRVHAAHGFAVETLRRFLDEADAAVDLKYRSPGEALDALRAGACDLAGVHLPIGEFERDILAHYAGRIDPHGDRVLHLATRRIGLILAPGNPKRIGTLADLLRSDVRFIHRQPGSGARLLLERMLARQGLSIHEVRGCGIDELTHAAVAAYVASGMADAGFGLETPARRYGLEFVPIASEHYFFLARESTLDSPALGDVLAILRSERFRAELGKLPGYDAGGCGEVQDLFEAFGSARAVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE45</accession>
    <name>A0A0S2DE45_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD dependent epimerase/dehydratase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1413</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946758.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1413"/>
    <dbReference type="EnsemblBacteria" id="ALN56770">
        <property type="protein sequence ID" value="ALN56770"/>
        <property type="gene ID" value="GLE_1413"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1413"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1393"/>
    <dbReference type="OMA" id="DWTFLSP"/>
    <dbReference type="OrthoDB" id="948454at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="7"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="216" mass="22534" checksum="B4366E97498B2826" modified="2016-02-17" version="1">MNIVLIGATGYVGRAVLEEALNRGHRVTAVARNTDSLPAHAGLTARAATVGGDDPAALAAALRGADAVIASFNAGGWQNPNLGADTVAGYGQIVAATKQAGVPRLLVVGGAGSLEVAPGQQVLDQPGFPDEYRAGAEAMRSVLKTLREERELDWTFLSPAAHLVPGERTGRFRLGGDQLLVDAAGESKISVQDYAVALIDELEQPAHSRKRFTLAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE99</accession>
    <name>A0A0S2DE99_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1528</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946852.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56885">
        <property type="protein sequence ID" value="ALN56885"/>
        <property type="gene ID" value="GLE_1528"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1528"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1510"/>
    <dbReference type="OMA" id="PMAQVVY"/>
    <dbReference type="OrthoDB" id="1725392at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038728">
        <property type="entry name" value="YkvI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37814">
        <property type="entry name" value="PTHR37814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="314"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="382" mass="40589" checksum="DDCF7E461972991F" modified="2016-02-17" version="1">MSAGAAPGSRFQRYLLPGFAFKAVVIGGGYATGRELVEFFLPAGAWGGVYAMAAATALWSLVCMLTFVLAQALRSFDYRSFFQRLLGPLWWTFELAYLALLIVLLAVFGAAAGAIGQAVFGWPPLAGAMCLVAAIAAVVSFGNESVERVFKWVSFFLYGVYALFAALALSAFGDRIQAAFAAPAAPAAGWLGDGLTYAGYNLVGAVVILPVARHFAGRRDAAVAGLLAGPLAMLPALAFFVCMVGFQDQIADAALPSDYLLQRLGLPWFHALFQLMVFAALLESGAGAVHAINERAAAAWRARRGREWPPRARLALAAALLLGSVFLADRFGLVALIASGYRGLSYLLLAVYVLPLLTRGVWLLRRRDPAPATAAPSLPSHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEA4</accession>
    <name>A0A0S2DEA4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1476</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56833">
        <property type="protein sequence ID" value="ALN56833"/>
        <property type="gene ID" value="GLE_1476"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1476"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1457"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="46" mass="4992" checksum="4F7174D9ACF48610" modified="2016-02-17" version="1">MTAPAPARLAPDQAGGVAASLTRDRNLRALERPSQPRSQPARRRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DED2</accession>
    <name>A0A0S2DED2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1559</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56916">
        <property type="protein sequence ID" value="ALN56916"/>
        <property type="gene ID" value="GLE_1559"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1559"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="64" mass="6814" checksum="27E99FF0D0A53167" modified="2016-02-17" version="1">MGIRGLEFGHGALLPGFARRGPRAREGIAAADRGVRRSVAAQAARRPAGAPYGNLTEREVLLFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEH1</accession>
    <name>A0A0S2DEH1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1567</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56924">
        <property type="protein sequence ID" value="ALN56924"/>
        <property type="gene ID" value="GLE_1567"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1567"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1547"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="113" mass="12617" checksum="8A10A23D27D9FC87" modified="2016-02-17" version="1">MDHLDTLPGLKYITRPAVLLGHEDIALALDSLEAAFGVVAQTPEQEFHGFTGYPIAQALLDTDDELCRRSPGEGADPYYLIMCLRAHRDVLMQANRTASLALYFSFHPYFDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEN1</accession>
    <name>A0A0S2DEN1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Formate-dependent phosphoribosylglycinamide formyltransferase</fullName>
            <ecNumber evidence="3">6.3.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">5'-phosphoribosylglycinamide transformylase 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Formate-dependent GAR transformylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">GAR transformylase 2</fullName>
            <shortName evidence="3">GART 2</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Non-folate glycinamide ribonucleotide transformylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Phosphoribosylglycinamide formyltransferase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">purT</name>
        <name evidence="7" type="ORF">FE772_08275</name>
        <name evidence="6" type="ORF">GLE_1590</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>ATP + formate + N(1)-(5-phospho-beta-D-ribosyl)glycinamide = ADP + H(+) + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide + phosphate</text>
            <dbReference type="Rhea" id="RHEA:24829"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; IMP biosynthesis via de novo pathway; N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-phospho-D-ribosyl)glycinamide (formate route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PurK/PurT family.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.21" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946903.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1590"/>
    <dbReference type="EnsemblBacteria" id="ALN56947">
        <property type="protein sequence ID" value="ALN56947"/>
        <property type="gene ID" value="GLE_1590"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1590"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1570"/>
    <dbReference type="OMA" id="GMVTMIT"/>
    <dbReference type="OrthoDB" id="1677960at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00127"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043815">
        <property type="term" value="F:phosphoribosylglycinamide formyltransferase 2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004644">
        <property type="term" value="F:phosphoribosylglycinamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01643">
        <property type="entry name" value="PurT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003135">
        <property type="entry name" value="ATP-grasp_carboxylate-amine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005862">
        <property type="entry name" value="PurT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02222">
        <property type="entry name" value="ATP-grasp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01142">
        <property type="entry name" value="purT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 3" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP-grasp" evidence="5">
        <location>
            <begin position="130"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="5'-phosphoribosylglycinamide binding" evidence="3">
        <location>
            <begin position="22"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="5'-phosphoribosylglycinamide binding" evidence="3">
        <location>
            <begin position="373"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>N(1)-(5-phospho-beta-D-ribosyl)glycinamide</name>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="171"/>
            <end position="176"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="206"/>
            <end position="209"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>N(1)-(5-phospho-beta-D-ribosyl)glycinamide</name>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="366"/>
        </location>
        <ligand>
            <name>N(1)-(5-phospho-beta-D-ribosyl)glycinamide</name>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN56947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW25666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="404" mass="43738" checksum="AC07E39368E5AA80" modified="2016-02-17" version="1">MTTLGTPLSPHAYRVLLLGSGELGKEVAIELQRFGVEVIAADRYADAPAMQVAHRSHVLDMLDGQAVRALIAAERPNLIVPEIEAIHTQTLVELEDEFARRGSDTRVAPTRIIPTARAARLTMDREGIRRLAAETLKLATSPYRFVDTREDYRAAVAEIGLPCVVKPVMSSSGKGQSLVRGEADIDKAWDYAQTGGRAGAGRVIVEGFIDFDYEITLLTVRHAGGTTFCAPIGHLQRDGDYRESWQPQPMNPVALARAQEIARAITDDLGGFGVFGVELFVKGDEVWFSEVSPRPHDTGLVTLISQDLSEFALHARAILGLPIPTIREHGPSSSCAVLAQGHGVPVFSGVDAALGQVDTQLRLFGKPRVEGHRRVAVTLALGGDINEARAKAREAAAQLRIELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEQ2</accession>
    <name>A0A0S2DEQ2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Acyl carrier protein</fullName>
            <shortName evidence="8">ACP</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 13" type="primary">acpP</name>
        <name evidence="14" type="ORF">BV903_07285</name>
        <name evidence="16" type="ORF">D9T17_18800</name>
        <name evidence="15" type="ORF">FE772_08775</name>
        <name evidence="12" type="ORF">GLE_1693</name>
        <name evidence="13" type="ORF">LEN_3272</name>
        <name evidence="17" type="ORF">SAMN05421681_104503</name>
    </gene>
    <organism evidence="12 18">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 18" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 18">C3</strain>
        </source>
    </reference>
    <reference evidence="21" key="2">
        <citation type="journal article" date="2016" name="DNA Res." volume="0" first="0" last="0">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer, Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">M497-1</strain>
        </source>
    </reference>
    <reference evidence="17 19" key="3">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">ATCC 29487</strain>
        </source>
    </reference>
    <reference evidence="13 21" key="4">
        <citation type="journal article" date="2017" name="DNA Res." volume="24" first="169" last="177">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
            <dbReference type="PubMed" id="28065880"/>
            <dbReference type="DOI" id=".1093/dnares/dsw055"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 21">M497-1</strain>
        </source>
    </reference>
    <reference evidence="14 20" key="5">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 20">B25</strain>
        </source>
    </reference>
    <reference evidence="16 22" key="6">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 22">OH11</strain>
        </source>
    </reference>
    <reference evidence="15 23" key="7">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 23">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 10">Carrier of the growing fatty acid chain in fatty acid biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Glycolipid biosynthesis; KDO(2)-lipid A biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8 10">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="8">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.</text>
    </comment>
    <comment type="PTM">
        <text evidence="10">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the acyl carrier protein (ACP) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP014940">
        <property type="protein sequence ID" value="BAV98759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000013">
        <property type="protein sequence ID" value="OPD64682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000045">
        <property type="protein sequence ID" value="ROU05462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNOG01000004">
        <property type="protein sequence ID" value="SDX29460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_031373652.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1693"/>
    <dbReference type="EnsemblBacteria" id="ALN57049">
        <property type="protein sequence ID" value="ALN57049"/>
        <property type="gene ID" value="GLE_1693"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAV98759">
        <property type="protein sequence ID" value="BAV98759"/>
        <property type="gene ID" value="LEN_3272"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64682">
        <property type="protein sequence ID" value="OPD64682"/>
        <property type="gene ID" value="BV903_07285"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDX29460">
        <property type="protein sequence ID" value="SDX29460"/>
        <property type="gene ID" value="SAMN05421681_104503"/>
    </dbReference>
    <dbReference type="KEGG" id="lem:LEN_3272"/>
    <dbReference type="KEGG" id="lez:GLE_1693"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1671"/>
    <dbReference type="OMA" id="CEIPDEQ"/>
    <dbReference type="OrthoDB" id="1943389at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="UniPathway" id="UPA00360"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000183696">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000218824">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000036">
        <property type="term" value="F:acyl carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036104">
        <property type="term" value="P:Kdo2-lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01217">
        <property type="entry name" value="Acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003231">
        <property type="entry name" value="Acyl_carrier"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863">
        <property type="entry name" value="PTHR20863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00517">
        <property type="entry name" value="acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="1 8 9" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3 8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="11">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="8 9">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN57049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="BAV98759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OPD64682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW25747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROU05462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="SDX29460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000183696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000218824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="79" mass="8829" checksum="FDB99F484B354895" modified="2016-02-17" version="1">MSSIEERVKKIVVEQLGVKEEEVTNNASFVDDLGADSLDTVELVMALEEEFECEIPDEEAEKITSVQQAIDYVKAHVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFB1</accession>
    <name>A0A0S2DFB1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleoid-associated protein BV903_07200</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BV903_07200</name>
        <name evidence="7" type="ORF">D9T17_18890</name>
        <name evidence="6" type="ORF">FE772_08690</name>
        <name evidence="3" type="ORF">GLE_1676</name>
        <name evidence="4" type="ORF">LEN_3290</name>
        <name evidence="8" type="ORF">SAMN05421681_104520</name>
    </gene>
    <organism evidence="3 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 9">C3</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2016" name="DNA Res." volume="0" first="0" last="0">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer, Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M497-1</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="3">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">ATCC 29487</strain>
        </source>
    </reference>
    <reference evidence="4 12" key="4">
        <citation type="journal article" date="2017" name="DNA Res." volume="24" first="169" last="177">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
            <dbReference type="PubMed" id="28065880"/>
            <dbReference type="DOI" id=".1093/dnares/dsw055"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 12">M497-1</strain>
        </source>
    </reference>
    <reference evidence="5 11" key="5">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 11">B25</strain>
        </source>
    </reference>
    <reference evidence="7 13" key="6">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 13">OH11</strain>
        </source>
    </reference>
    <reference evidence="6 14" key="7">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the YbaB/EbfC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP014940">
        <property type="protein sequence ID" value="BAV98777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000013">
        <property type="protein sequence ID" value="OPD64667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000045">
        <property type="protein sequence ID" value="ROU05477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNOG01000004">
        <property type="protein sequence ID" value="SDX29947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946968.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1676"/>
    <dbReference type="EnsemblBacteria" id="ALN57032">
        <property type="protein sequence ID" value="ALN57032"/>
        <property type="gene ID" value="GLE_1676"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAV98777">
        <property type="protein sequence ID" value="BAV98777"/>
        <property type="gene ID" value="LEN_3290"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64667">
        <property type="protein sequence ID" value="OPD64667"/>
        <property type="gene ID" value="BV903_07200"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDX29947">
        <property type="protein sequence ID" value="SDX29947"/>
        <property type="gene ID" value="SAMN05421681_104520"/>
    </dbReference>
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    <dbReference type="PATRIC" id="fig|69.6.peg.1654"/>
    <dbReference type="OMA" id="MGNMMKQ"/>
    <dbReference type="OrthoDB" id="1883809at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000183696">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000218824">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043590">
        <property type="term" value="C:bacterial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1310.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00274">
        <property type="entry name" value="DNA_YbaB_EbfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036894">
        <property type="entry name" value="YbaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004401">
        <property type="entry name" value="YbaB/EbfC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33449">
        <property type="entry name" value="PTHR33449"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02575">
        <property type="entry name" value="YbaB_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004555">
        <property type="entry name" value="UCP004555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82607">
        <property type="entry name" value="SSF82607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00103">
        <property type="entry name" value="DNA_YbaB_EbfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="5"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAV98777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD64667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW25732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROU05477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDX29947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000183696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000218824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="106" mass="11396" checksum="3452B5BD1DDA56FF" modified="2016-02-17" version="1">MRGNIAQLMQQAQKMQENVQRAQEELAKIEVTGSAGGGMVSITVTGRMECRKVRIDPSVLSDQEMVEDLIAAAFNDAVNKINAESQAKMSAATAGMPMPPGMKLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFP9</accession>
    <name>A0A0S2DFP9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Zn-dependent enzyme from deacylase/carboxypeptidase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_10205</name>
        <name evidence="5" type="ORF">GLE_2011</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947209.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2011"/>
    <dbReference type="EnsemblBacteria" id="ALN57361">
        <property type="protein sequence ID" value="ALN57361"/>
        <property type="gene ID" value="GLE_2011"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2011"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1976"/>
    <dbReference type="OMA" id="WNIPDGF"/>
    <dbReference type="OrthoDB" id="397741at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007036">
        <property type="entry name" value="Aste_AspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04952">
        <property type="entry name" value="AstE_AspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW25986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="308" mass="33714" checksum="4DC7067BA5A9BC02" modified="2016-02-17" version="1">MSTATAFYPIGTPGQAWGPAEVAEWRSRQVRHRSYFDEVANVIERLGERYEKIQYGELDYGADGRFPLFALKSRNWDDALPTMLVTGGVHGYETSGVHGALLFLDQDAGAYAGRINLLVAPCVSPWAYERIHRWNPDAIDPNRSFRDDSPAGESAALWALAAPLRASALMHIDLHETTDSDESEFRPALAARDGKPYEPGEIPDGFYLVGDSEDPQPRFQQAIIAEVEKVTHIAPADARGEIIGSPVVARGVIDYPVRKLGLCAGITDARYRTTTEVYPDSPRATPEQCNQAQAAAVRAAIDFALAQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFQ0</accession>
    <name>A0A0S2DFQ0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fused isobutyryl-CoA mutase</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="5">Isobutyryl-CoA mutase</fullName>
                <shortName evidence="5">ICM</shortName>
                <ecNumber evidence="5">5.4.99.13</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="5">P-loop GTPase</fullName>
                <ecNumber evidence="5">3.6.5.-</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="5">G-protein chaperone</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="7" type="primary">mutA</name>
        <name evidence="5" type="synonym">icmF</name>
        <name evidence="8" type="ORF">FE772_10060</name>
        <name evidence="7" type="ORF">GLE_1980</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>2-methylpropanoyl-CoA = butanoyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:13141"/>
            <dbReference type="ChEBI" id="CHEBI:57338"/>
            <dbReference type="ChEBI" id="CHEBI:57371"/>
            <dbReference type="EC" id="5.4.99.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="domain">
        <text evidence="5">Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the IcmF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.13" evidence="5"/>
    <dbReference type="EC" id="3.6.5.-" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947185.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1980"/>
    <dbReference type="EnsemblBacteria" id="ALN57330">
        <property type="protein sequence ID" value="ALN57330"/>
        <property type="gene ID" value="GLE_1980"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1980"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1945"/>
    <dbReference type="OMA" id="LAMFMNT"/>
    <dbReference type="OrthoDB" id="154460at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047727">
        <property type="term" value="F:isobutyryl-CoA mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034784">
        <property type="term" value="F:pivalyl-CoA mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006637">
        <property type="term" value="P:acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02050">
        <property type="entry name" value="IcmF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016176">
        <property type="entry name" value="Cbl-dep_enz_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033669">
        <property type="entry name" value="IcmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006099">
        <property type="entry name" value="MeMalonylCoA_mutase_a/b_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01642">
        <property type="entry name" value="MM_CoA_mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51703">
        <property type="entry name" value="SSF51703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2 5" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="4 5" id="KW-0170">Cobalt</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B12-binding" evidence="6">
        <location>
            <begin position="17"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </ligand>
        <ligandPart>
            <name>Co</name>
            <dbReference type="ChEBI" id="CHEBI:27638"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="211"/>
            <end position="216"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="301"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="348"/>
            <end position="351"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="678"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="827"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="871"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="920"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="955"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="960"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="1192"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW25959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="1193" mass="133183" checksum="B918673C90220B80" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFQ4</accession>
    <name>A0A0S2DFQ4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BV903_17360</name>
        <name evidence="8" type="ORF">FE772_09770</name>
        <name evidence="6" type="ORF">GLE_1913</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">C3</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000046">
        <property type="protein sequence ID" value="OPD62698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947140.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000046.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57264">
        <property type="protein sequence ID" value="ALN57264"/>
        <property type="gene ID" value="GLE_1913"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62698">
        <property type="protein sequence ID" value="OPD62698"/>
        <property type="gene ID" value="BV903_17360"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1913"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1881"/>
    <dbReference type="OMA" id="WQLTMIS"/>
    <dbReference type="OrthoDB" id="527053at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
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</entry>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">C3</strain>
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    <sequence length="226" mass="23902" checksum="5C437F6C4B717BCA" modified="2016-02-17" version="1">MSRPSLLRATALLAATFAGAFACNGVAAAPTPPSAAASPPDRAVDAARGCWIQRDAPDGRASALLRLLPDRDHPEWLSVQLSRPEGDDPDRRVQLWLARDGRSAVLASRPLADPRAPAPAAADEPQLRPLAPTHAPGRAPGSTQTLVLFPQARIEFARVPERPVPAGDWPRDTLSAEFLAGAGTGPSRRLRVQASEERLALILVSARGTGAGRDTPLFDGRRDGCD</sequence>
</entry>
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</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
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        </submittedName>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Feng T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">YC36</strain>
        </source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW26174.1"/>
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    </evidence>
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        <source>
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        <source>
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    </evidence>
    <sequence length="552" mass="62236" checksum="94D9BFB74B618389" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGA9</accession>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW25993.1"/>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57368">
        <property type="protein sequence ID" value="ALN57368"/>
        <property type="gene ID" value="GLE_2018"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2018"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1983"/>
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    <dbReference type="Proteomes" id="UP000061569">
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242562" evidence="1">
        <location>
            <begin position="22"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="168" mass="18090" checksum="90F783268D52A30B" modified="2016-02-17" version="1">MKRLVPLAWLACALLPLAAVAADDAALEKGLTDAMRYDRAKGERAAPSGPALQAYIQAGYLELKPSVRADYTDYRLLKKPAPFMGQALVMVEEEYMTQYIGCCVDEGVSAVVRVDGSTAAMETFAKANACSFEPKYDPAEALTANRLGIGLPPGKYAKLSCHERDANP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGI1</accession>
    <name>A0A0S2DGI1_LYSEN</name>
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        <submittedName>
            <fullName evidence="1">SapC family protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">GLE_2326</name>
    </gene>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
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            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_2326"/>
    <dbReference type="EnsemblBacteria" id="ALN57675">
        <property type="protein sequence ID" value="ALN57675"/>
        <property type="gene ID" value="GLE_2326"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2326"/>
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    <dbReference type="OMA" id="MNILRYP"/>
    <dbReference type="OrthoDB" id="1512520at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010836">
        <property type="entry name" value="SapC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07277">
        <property type="entry name" value="SapC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="252" mass="27892" checksum="E0FA442970CFB854" modified="2016-02-17" version="1">MLIYDRVVPLNRETHRRLRIRTAQHNARFAASLNSVPVATIEFPAAANEYAIVFAKLANGDFLPAVLVGLRSQQNLYVDENARWRRGYVPAFLRQYPFVLAEDADTGTVTVCVDLAYDGLSEDEGEPLFGEDGGDTESLTRAVNFLQELHGEFKRTAAFAAKIKELDLLEEKVIRFGNPDQPQAELNGVYAVSEEKLMKLTDAQLPELFRTGVLGLIYTHLLSMRNLERLSELAQQAPATAAANAPQGDAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGW3</accession>
    <name>A0A0S2DGW3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_12100</name>
        <name evidence="2" type="ORF">GLE_2420</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57769">
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        <property type="gene ID" value="GLE_2420"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2420"/>
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    <dbReference type="OMA" id="DWWTKSL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="99" mass="10456" checksum="5C5E3533D4807E3D" modified="2016-02-17" version="1">MSGERLQSRHWLGKGSAGLILGFGLALALSGVFAWLGPDGIHGGGGGKIQFVMWLIAPLWCAVFSLVFLFRSSVRAWLWLGAANALAFAALAALRSWAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH36</accession>
    <name>A0A0S2DH36_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inosose dehydratase</fullName>
            <ecNumber evidence="3">4.2.1.-</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Sugar phosphate isomerase/epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">iolE</name>
        <name evidence="4" type="ORF">FE772_13105</name>
        <name evidence="3" type="ORF">GLE_2611</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.2.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947676.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2611"/>
    <dbReference type="EnsemblBacteria" id="ALN57959">
        <property type="protein sequence ID" value="ALN57959"/>
        <property type="gene ID" value="GLE_2611"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2611"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2571"/>
    <dbReference type="OMA" id="VDCKEAR"/>
    <dbReference type="OrthoDB" id="1169054at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="2">
        <location>
            <begin position="29"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="350" mass="39183" checksum="C83E3E8AD7C2546C" modified="2016-02-17" version="1">MKTLKGPALFLAQFIGDKPPFDRLDTLAEWAAGLGYSGVQVPTSAPHLFDLAQAARSQAYCDDVAATLARHGIEITELSTHLQGQLIAVHPAYDILFDGFAPAEKRGDPPARQAWAVEQLMLAAQASQRLGLSAHATFSGALAWPYFYPWPQRPHGLVDAAFAELGRRWRPILDAFDACGVDLCYEIHPGEDLHDGATFERFLDVVDHHRRAKILYDPSHLLLQQMDYLGFIDRYHERIGIFHVKDAEYRATARSGVYGGYQDWIDRPGRFRSLGDGQVDFKAIFSKLAQYDFPGWAVLEWECCLKHPEDGAREGAAFIRDHLIRVTERAFDDFADSGASPERTRSLLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH46</accession>
    <name>A0A0S2DH46_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">BON domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Transport-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_11820</name>
        <name evidence="4" type="ORF">GLE_2361</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947478.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57710">
        <property type="protein sequence ID" value="ALN57710"/>
        <property type="gene ID" value="GLE_2361"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2361"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2322"/>
    <dbReference type="OMA" id="QPVSDTW"/>
    <dbReference type="OrthoDB" id="2004166at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007055">
        <property type="entry name" value="BON_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014004">
        <property type="entry name" value="Transpt-assoc_nodulatn_dom_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04972">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00749">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50914">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726562" evidence="2">
        <location>
            <begin position="26"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="BON" evidence="3">
        <location>
            <begin position="51"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="121" mass="12024" checksum="A89FE7B356B3311F" modified="2016-02-17" version="1">MKTAHMKTLSIAAALGLALSTAAGAQTAGTRADAAQDPAATAAGDSQQPVGDTWITTKVKTELMATGGVPGTDIKVETVNGVVMLSGSVSKAQADKAASIARNIDGVKKVDTSGLTVSKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH77</accession>
    <name>A0A0S2DH77_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AcrB multidrug efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_2599</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947667.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2599"/>
    <dbReference type="EnsemblBacteria" id="ALN57947">
        <property type="protein sequence ID" value="ALN57947"/>
        <property type="gene ID" value="GLE_2599"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2599"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2559"/>
    <dbReference type="OMA" id="GVVMKNT"/>
    <dbReference type="OrthoDB" id="145346at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="360"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="390"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="463"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="525"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="852"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="878"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="904"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="951"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="982"/>
            <end position="1008"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1026" mass="109710" checksum="145B11B9F05DD11E" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH93</accession>
    <name>A0A0S2DH93_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57963">
        <property type="protein sequence ID" value="ALN57963"/>
        <property type="gene ID" value="GLE_2615"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2615"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2575"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="85" mass="9525" checksum="09FDDB5E2848E336" modified="2016-02-17" version="1">MDGWKGVVAVIMYTLIFVKDLDAQFPKTLYMIETGEGIAFGPEEMKRAIEAALASRDDLSELLDQPHSDGALRSYFAKILMHLPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHB6</accession>
    <name>A0A0S2DHB6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Beta-ketoacyl synthase/short chain dehydrogenase/methyltransferase domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLE_2495</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947582.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2495"/>
    <dbReference type="EnsemblBacteria" id="ALN57844">
        <property type="protein sequence ID" value="ALN57844"/>
        <property type="gene ID" value="GLE_2495"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2495"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2458"/>
    <dbReference type="OMA" id="ESMVACE"/>
    <dbReference type="OrthoDB" id="1123553at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3 6" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="8">
        <location>
            <begin position="1181"/>
            <end position="1258"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="8">
        <location>
            <begin position="3187"/>
            <end position="3265"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="8">
        <location>
            <begin position="3327"/>
            <end position="3401"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="8">
        <location>
            <begin position="3454"/>
            <end position="3531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="648"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1135"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1274"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2250"/>
            <end position="2305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="3293"/>
            <end position="3314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="3406"/>
            <end position="3459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="3533"/>
            <end position="3563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="3406"/>
            <end position="3430"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="6">
        <location>
            <position position="1218"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="6">
        <location>
            <position position="3225"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="6">
        <location>
            <position position="3361"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="6">
        <location>
            <position position="3491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN57844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="3563" mass="376763" checksum="A7A1104909B1981C" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHB9</accession>
    <name>A0A0S2DHB9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Replicative DNA helicase</fullName>
            <ecNumber evidence="4 13">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">dnaB</name>
        <name evidence="17" type="ORF">BV903_18665</name>
        <name evidence="19" type="ORF">D9T17_15335</name>
        <name evidence="18" type="ORF">FE772_13270</name>
        <name evidence="15" type="ORF">GLE_2647</name>
        <name evidence="16" type="ORF">LEN_2391</name>
    </gene>
    <organism evidence="15 20">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="15 20" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 20">C3</strain>
        </source>
    </reference>
    <reference evidence="22" key="2">
        <citation type="journal article" date="2016" name="DNA Res." volume="0" first="0" last="0">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer, Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22">M497-1</strain>
        </source>
    </reference>
    <reference evidence="16 22" key="3">
        <citation type="journal article" date="2017" name="DNA Res." volume="24" first="169" last="177">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
            <dbReference type="PubMed" id="28065880"/>
            <dbReference type="DOI" id=".1093/dnares/dsw055"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 22">M497-1</strain>
        </source>
    </reference>
    <reference evidence="17 21" key="4">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 21">B25</strain>
        </source>
    </reference>
    <reference evidence="19 23" key="5">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 23">OH11</strain>
        </source>
    </reference>
    <reference evidence="18 24" key="6">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 24">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13">Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the helicase family. DnaB subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="4 13"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP014940">
        <property type="protein sequence ID" value="BAV97878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000052">
        <property type="protein sequence ID" value="OPD62380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000037">
        <property type="protein sequence ID" value="ROU06064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947702.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000037.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2647"/>
    <dbReference type="EnsemblBacteria" id="ALN57995">
        <property type="protein sequence ID" value="ALN57995"/>
        <property type="gene ID" value="GLE_2647"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAV97878">
        <property type="protein sequence ID" value="BAV97878"/>
        <property type="gene ID" value="LEN_2391"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62380">
        <property type="protein sequence ID" value="OPD62380"/>
        <property type="gene ID" value="BV903_18665"/>
    </dbReference>
    <dbReference type="KEGG" id="lem:LEN_2391"/>
    <dbReference type="KEGG" id="lez:GLE_2647"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2606"/>
    <dbReference type="OMA" id="IEFHARI"/>
    <dbReference type="OrthoDB" id="1709134at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000218824">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00984">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036185">
        <property type="entry name" value="DNA_heli_DnaB-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007692">
        <property type="entry name" value="DNA_helicase_DnaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007693">
        <property type="entry name" value="DNA_helicase_DnaB-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016136">
        <property type="entry name" value="DNA_helicase_N/primase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00772">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03796">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48024">
        <property type="entry name" value="SSF48024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00665">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="12 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 13 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="9 13 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 13" id="KW-0639">Primosome</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SF4 helicase" evidence="14">
        <location>
            <begin position="199"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ALN57995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="BAV97878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OPD62380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="QCW26489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ROU06064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000218824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="470" mass="52246" checksum="2CC6257059F98BA3" modified="2016-02-17" version="1">MSSRPGFRGEKRFETRAEQRIDQLRVPPQSVEAEQAVLGGLMLAPDAYDRVADQLVEEDFYRRDHQLIYRAIRELAERSRPFDAVTLGEWFDSQGLSEQVAGGAYLIELATTTPSAANIAAYAEIVRDKAVMRKLIEVGTEIVNDGFQPDGRDSSEILSKAEQQVFAIAEAGARGRTDFTPVTKALSEAFDVLQTRYANGGAVTGLPTGYTEFDEMTAGLQNTDLLILAARPAMGKTTFALNIAEHVAFRTKKAVAVFSMEMSASQLALRLISSVGRVNAQRLRSGQLEDEDWARVTGAIRQLREVKIFIDDTPGLSPDVLRAKSRRLKREHDLGLIVIDYLQLMSVPGNQENRATEISEISRSLKHLAKELNLPVIALSQLNRSLEQRADKRPVMADLRESGAIEQDADIIIFIYRDDYYNKETSPDKGLAEVIIGKQRSGPTGSLKLKFFGEYTRFDNLAHDSIGSFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHE3</accession>
    <name>A0A0S2DHE3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_01435</name>
        <name evidence="3" type="ORF">FE772_12355</name>
        <name evidence="1" type="ORF">GLE_2473</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000003">
        <property type="protein sequence ID" value="OPD65686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947562.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57822">
        <property type="protein sequence ID" value="ALN57822"/>
        <property type="gene ID" value="GLE_2473"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65686">
        <property type="protein sequence ID" value="OPD65686"/>
        <property type="gene ID" value="BV903_01435"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2473"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2435"/>
    <dbReference type="OrthoDB" id="2130250at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD65686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="125" mass="13585" checksum="EDA121197197756A" modified="2016-02-17" version="1">MKVFARITQYNPVLLVCDSGALNLPPLSGKLPIQANDACIAIRNATANGLPVRLLVSDEFVARPGELVCTRRLVTPNRAVVVTSVLLETFAAVVTRRTQSLVRVYANDPLVPDRIVVIVGEHMQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHF2</accession>
    <name>A0A0S2DHF2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_13705</name>
        <name evidence="3" type="ORF">GLE_2739</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947778.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58087">
        <property type="protein sequence ID" value="ALN58087"/>
        <property type="gene ID" value="GLE_2739"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2739"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2697"/>
    <dbReference type="OrthoDB" id="1650051at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242315" evidence="2">
        <location>
            <begin position="29"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="353" mass="38032" checksum="26DE01CCC14D75E7" modified="2016-02-17" version="1">MSAAKRAGRVALPAAASLALCAALLALAPGCKRTGASTSSQAAEASVAPAPAPATDPALNWGGTTPHDKPPLPDPLIAQAEAVMRKADPVFDKFEVNYVTGDLDRAGRDDVVIEYGIGDEGAMRHIAKSVRVLLARDGGLQLQADQTDKFEDCPAVRAIRDGRLWADGLEACMLPFPRTLNYYQFEWRNGALVRVSTEDARQRVLSRLRAMREAIEAGKRSALDANLRPGPPIHGEAAPAPDPVFADADRRRAFADAVGLLSRLELKRLGPHESVVSFVKPRGADAGERKLLIDTAPDDATVEIDGYTYVVDARATVEWPEGDGVGYHLRWRLIDGELYLEEADAHDLDGLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHJ6</accession>
    <name>A0A0S2DHJ6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57994">
        <property type="protein sequence ID" value="ALN57994"/>
        <property type="gene ID" value="GLE_2646"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2646"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2605"/>
    <dbReference type="OMA" id="TPCMIFI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="580" mass="63630" checksum="508146B581F4F276" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHK7</accession>
    <name>A0A0S2DHK7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GMC family oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">GMC oxidoreductase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_00205</name>
        <name evidence="5" type="ORF">FE772_13070</name>
        <name evidence="3" type="ORF">GLE_2604</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000001">
        <property type="protein sequence ID" value="OPD65972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947670.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2604"/>
    <dbReference type="EnsemblBacteria" id="ALN57952">
        <property type="protein sequence ID" value="ALN57952"/>
        <property type="gene ID" value="GLE_2604"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65972">
        <property type="protein sequence ID" value="OPD65972"/>
        <property type="gene ID" value="BV903_00205"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2604"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2564"/>
    <dbReference type="OMA" id="NLPAWIC"/>
    <dbReference type="OrthoDB" id="365211at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMC_OxRdtase_N" evidence="1">
        <location>
            <begin position="222"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="GMC_oxred_C" evidence="2">
        <location>
            <begin position="425"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD65972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="561" mass="62601" checksum="871BDB30A716CEAE" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHM3</accession>
    <name>A0A0S2DHM3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glucose-6-phosphate 1-dehydrogenase</fullName>
            <shortName evidence="4">G6PD</shortName>
            <ecNumber evidence="4">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 8" type="primary">zwf</name>
        <name evidence="9" type="ORF">FE772_13860</name>
        <name evidence="8" type="ORF">GLE_2775</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15841"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="1.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glucose-6-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947805.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2775"/>
    <dbReference type="EnsemblBacteria" id="ALN58123">
        <property type="protein sequence ID" value="ALN58123"/>
        <property type="gene ID" value="GLE_2775"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2775"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2732"/>
    <dbReference type="OMA" id="TWNNKHI"/>
    <dbReference type="OrthoDB" id="1153269at2"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00408"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004345">
        <property type="term" value="F:glucose-6-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00966">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022675">
        <property type="entry name" value="G6P_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
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    </dbReference>
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        <property type="entry name" value="PTHR23429"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="G6PD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="G6PDHDRGNASE"/>
    </dbReference>
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        <property type="entry name" value="SSF51735"/>
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    </dbReference>
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        <property type="entry name" value="zwf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 4" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="2 4" id="KW-0521">NADP</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="7"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="G6PD_C" evidence="7">
        <location>
            <begin position="177"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="449"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="228"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="83"/>
            <end position="84"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
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        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW26585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="479" mass="53359" checksum="67E4AF42B3D72E38" modified="2016-02-17" version="1">MHDTLLLFGATGDLSQRYLFPSLVHLWRDRLLPATLRIVAVGRQEHSDEEFRAWLRERMAAEVADDPGIVEDLLARMHYVSVDLRDEAAIAAALSAYADRPSVSYLATPPDLFVPCAKGLKAAGLLEGESRLVLEKPIGRDLASAREINAALRACLDESRIFRIDHYLGKAAVQNLLALRFGNTLLEAVWQHRWIESVDIFVGETAGVDGREGYYAGYGALRDMVQNHMLQLLALIAMEPPSALDADSIRDEKRKVLRALRPVTTADAAQRTVRGRYGAGVVEGRAVKGFVHESPVETFVAVETFIDNWRWAGVPFRLVTGKRLAERATEVVVSFRPTSHWLFERPRRGRERPNRLRMRLQPDETIELGLMGSLAAPEWGALELKPMSLDLSMSGSPQRRIAYERLIVDALRGNQTLFVRDDEVEAAWQWIDSIEHAWSETAQPALEYPAGSWGPAEAERFLPPTNGGTHSNRTGGGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHQ9</accession>
    <name>A0A0S2DHQ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">(2,3-dihydroxybenzoyl)adenylate synthase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">2,3-dihydroxybenzoate-AMP ligase</fullName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">dhbE</name>
        <name evidence="6" type="ORF">FE772_13155</name>
        <name evidence="5" type="ORF">GLE_2623</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Siderophore biosynthesis.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.58" evidence="5 6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW26470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947685.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2623"/>
    <dbReference type="EnsemblBacteria" id="ALN57971">
        <property type="protein sequence ID" value="ALN57971"/>
        <property type="gene ID" value="GLE_2623"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2623"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2582"/>
    <dbReference type="OMA" id="PNIRFIR"/>
    <dbReference type="OrthoDB" id="1015470at2"/>
    <dbReference type="UniPathway" id="UPA00394">
        <property type="reaction ID" value="UER00650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008668">
        <property type="term" value="F:(2,3-dihydroxybenzoyl)adenylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019290">
        <property type="term" value="P:siderophore biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011963">
        <property type="entry name" value="DHB_AMP_lig"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
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    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02275">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AMP-binding" evidence="3">
        <location>
            <begin position="37"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="4">
        <location>
            <begin position="448"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW26470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="552" mass="60355" checksum="3E81F2F518AFF2BB" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHY6</accession>
    <name>A0A0S2DHY6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2-amino-3-carboxymuconate 6-semialdehyde decarboxylase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_13405</name>
        <name evidence="3" type="ORF">GLE_2676</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947726.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2676"/>
    <dbReference type="EnsemblBacteria" id="ALN58024">
        <property type="protein sequence ID" value="ALN58024"/>
        <property type="gene ID" value="GLE_2676"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2676"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2635"/>
    <dbReference type="OMA" id="TTNYKAI"/>
    <dbReference type="OrthoDB" id="1832218at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="PTHR21240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="4"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="336" mass="38198" checksum="4AB03A88562AC1B6" modified="2016-02-17" version="1">MLKIDTHAHYLPRDWPDLARKYGDDRFPVIHHTDDGRHRIYKDGKFFREIWSKTWDPQERIDDYARFGVQVQVISTVPVMFSYWAKANQALALHQALNEHMSQTCRDFPRHYAGIGTVPLQSPRLAVQELERCMDQLGLQGVQIGSHIGDWNLDAPELFEFFQAASELGAAILVHPWDMMGTPSMPKYWLPWLVGMPAEQSRAACCLVFGGVLERLPKLKICMAHGGGSFPYTIGRIEHGFNMRPDLVATDNPRNPREYLSRLYFDSWVADPRALRYLLDTCGVSRVMLGTDYPFPLGEQTPGAGIASLDLPEAEQARLYHGTALEWLGLPLSRFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI14</accession>
    <name>A0A0S2DI14_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Adenylosuccinate lyase</fullName>
            <shortName evidence="11">ASL</shortName>
            <ecNumber evidence="4 11">4.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Adenylosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">purB</name>
        <name evidence="15" type="ORF">FE772_13600</name>
        <name evidence="14" type="ORF">GLE_2716</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">C3</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + fumarate</text>
            <dbReference type="Rhea" id="RHEA:23920"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:23921"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N(6)-(1,2-dicarboxyethyl)-AMP = AMP + fumarate</text>
            <dbReference type="Rhea" id="RHEA:16853"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:16854"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.2" evidence="4 11"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947761.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2716"/>
    <dbReference type="EnsemblBacteria" id="ALN58064">
        <property type="protein sequence ID" value="ALN58064"/>
        <property type="gene ID" value="GLE_2716"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2716"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2675"/>
    <dbReference type="OMA" id="TQVNPCD"/>
    <dbReference type="OrthoDB" id="347727at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00132"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00336"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070626">
        <property type="term" value="F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004018">
        <property type="term" value="F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004769">
        <property type="entry name" value="Pur_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013539">
        <property type="entry name" value="PurB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08328">
        <property type="entry name" value="ASL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00928">
        <property type="entry name" value="purB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 11" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lyase_1" evidence="12">
        <location>
            <begin position="17"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="ASL_C" evidence="13">
        <location>
            <begin position="334"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN58064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW26543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="458" mass="50178" checksum="82E3883496D63F27" modified="2016-02-17" version="1">MSADSQTTLLALSPLDGRYAGKVDALRPIFSEFGLIKARVKVEVEWLLALADEPAIVELAPFSAAAAARLRALAEHLSVEDAARVKEIERTTNHDVKAVEYLIKERLKDDAELGPALEFVHFACTSEDINNLSYALMLNQARQDVLLPKLDELIQKLRAMAHEHAALPMLSRTHGQTASPTTVGKEIANVVARLQRQGETLAGALMPGKINGAVGNYNAHVAAYPDIDWTAFSQRFVTSLGLDWQPYTTQIEPHDGIAEVCDAQRRIDTVCIDLCRDVWGYISLGYFKQAVKAGEVGSSTMPHKVNPIDFENAEGNFGIANALFEHFAAKLPISRWQRDLTDSTVLRALGTAFGHALIGFDALLRGLGKLSANPERLAADLDAAWEVLAEAVQTVMRRYGLPNPYEQLKALTRGQGINEASMREFIASLDLPEADKQRLLAMTPGSYVGLAEKLAREI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI67</accession>
    <name>A0A0S2DI67_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF1993 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_02530</name>
        <name evidence="3" type="ORF">FE772_14420</name>
        <name evidence="1" type="ORF">GLE_2886</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000005">
        <property type="protein sequence ID" value="OPD65420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947883.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58234">
        <property type="protein sequence ID" value="ALN58234"/>
        <property type="gene ID" value="GLE_2886"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65420">
        <property type="protein sequence ID" value="OPD65420"/>
        <property type="gene ID" value="BV903_02530"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2886"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2848"/>
    <dbReference type="OMA" id="NADEVFP"/>
    <dbReference type="OrthoDB" id="2020712at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018531">
        <property type="entry name" value="DUF1993"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36922">
        <property type="entry name" value="PTHR36922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09351">
        <property type="entry name" value="DUF1993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD65420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="169" mass="18687" checksum="6E212A9346C28B9A" modified="2016-02-17" version="1">MSLSLYDISVPAFQRGLDVLSHLLDQGIAHARAQGQDPERLLAGRLAPDMYTLVGQVQSASDAAKFGAARLAGIAPPSFADTETTLDELRERIAKTQEFLRTVTPQSMDGQEEREIVIRPGGRELRFVARDYIRGFVLPNFYFHLTTAYGILRHLGVPLGKMDYLRGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIB8</accession>
    <name>A0A0S2DIB8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Bifunctional protein FolD</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="10">Methylenetetrahydrofolate dehydrogenase</fullName>
                <ecNumber evidence="10">1.5.1.5</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="10">Methenyltetrahydrofolate cyclohydrolase</fullName>
                <ecNumber evidence="10">3.5.4.9</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="10 15" type="primary">folD</name>
        <name evidence="14" type="ORF">BV903_02610</name>
        <name evidence="15" type="ORF">FE772_14445</name>
        <name evidence="13" type="ORF">GLE_2895</name>
    </gene>
    <organism evidence="13 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">C3</strain>
        </source>
    </reference>
    <reference evidence="14 17" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">B25</strain>
        </source>
    </reference>
    <reference evidence="15 18" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 18">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:22812"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5,10-methenyltetrahydrofolate + H2O = (6S)-10-formyltetrahydrofolate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="EC" id="3.5.4.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.5" evidence="10"/>
    <dbReference type="EC" id="3.5.4.9" evidence="10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000005">
        <property type="protein sequence ID" value="OPD65431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947888.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000005.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2895"/>
    <dbReference type="EnsemblBacteria" id="ALN58243">
        <property type="protein sequence ID" value="ALN58243"/>
        <property type="gene ID" value="GLE_2895"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65431">
        <property type="protein sequence ID" value="OPD65431"/>
        <property type="gene ID" value="BV903_02610"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2895"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2857"/>
    <dbReference type="OMA" id="HIVGRPM"/>
    <dbReference type="OrthoDB" id="1449514at2"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004477">
        <property type="term" value="F:methenyltetrahydrofolate cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01080">
        <property type="entry name" value="NAD_bind_m-THF_DH_Cyclohyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01576">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000672">
        <property type="entry name" value="THF_DH/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020867">
        <property type="entry name" value="THF_DH/CycHdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020631">
        <property type="entry name" value="THF_DH/CycHdrlase_NAD-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02882">
        <property type="entry name" value="THF_DHG_CYH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00085">
        <property type="entry name" value="THFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00767">
        <property type="entry name" value="THF_DHG_CYH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="4 10 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 10" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5 10" id="KW-0521">NADP</keyword>
    <keyword evidence="1 10" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6 10 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THF_DHG_CYH" evidence="11">
        <location>
            <begin position="11"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="THF_DHG_CYH_C" evidence="12">
        <location>
            <begin position="129"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="171"/>
            <end position="173"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN58243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OPD65431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW26672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="296" mass="31424" checksum="91C47E31439BD34D" modified="2016-02-17" version="1">MTPPSHPARILDGKRIAEELLDNLKAQVDQRVARGLSRPGLAVVLVGSDPASSVYVRNKRRAAQKVGIRAIDYDLPADPGDEALLALIDKLNADPEVHGILVQLPLPDRRDATALIHRIDPRKDVDGFHPENVGHLMLRQFGLRPCTPRGITTLLGYTDRPVRGQSATIVGVSNHVGRPMALELLIAGCTVTSCHKFTPQAVLEQSVRNADILVVAVGRPGLIPGEWVKPGAVVIDVGINRLDDGRLVGDVGFAAAAQRASWITPVPGGVGPMTVATLMQNTLEAAEAADQAAGQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIM5</accession>
    <name>A0A0S2DIM5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_14670</name>
        <name evidence="2" type="ORF">GLE_2942</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2942"/>
    <dbReference type="EnsemblBacteria" id="ALN58290">
        <property type="protein sequence ID" value="ALN58290"/>
        <property type="gene ID" value="GLE_2942"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2942"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2904"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="75" mass="8013" checksum="46A6DCA497EB5F67" modified="2016-02-17" version="1">MAEWVRRSVKDVMIPIPGTSKRIQCSVALLMLGGGCGISDPNLNEQPAEARPPPDVPFKPHLQEDNGSVRPPPGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIP3</accession>
    <name>A0A0S2DIP3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">LexA repressor</fullName>
            <ecNumber evidence="12">3.4.21.88</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12 18" type="primary">lexA</name>
        <name evidence="17" type="ORF">BV903_09245</name>
        <name evidence="19" type="ORF">D9T17_12095</name>
        <name evidence="18" type="ORF">FE772_15930</name>
        <name evidence="16" type="ORF">GLE_3205</name>
    </gene>
    <organism evidence="16 20">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="16 20" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 20">C3</strain>
        </source>
    </reference>
    <reference evidence="17 21" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 21">B25</strain>
        </source>
    </reference>
    <reference evidence="19 22" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 22">OH11</strain>
        </source>
    </reference>
    <reference evidence="18 23" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 23">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Hydrolysis of Ala-|-Gly bond in repressor LexA.</text>
            <dbReference type="EC" id="3.4.21.88"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 12 13">Belongs to the peptidase S24 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.88" evidence="12"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000020">
        <property type="protein sequence ID" value="OPD64224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000030">
        <property type="protein sequence ID" value="ROU06738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948122.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000030.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3205"/>
    <dbReference type="EnsemblBacteria" id="ALN58551">
        <property type="protein sequence ID" value="ALN58551"/>
        <property type="gene ID" value="GLE_3205"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64224">
        <property type="protein sequence ID" value="OPD64224"/>
        <property type="gene ID" value="BV903_09245"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3205"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3160"/>
    <dbReference type="OMA" id="DDEFHIR"/>
    <dbReference type="OrthoDB" id="1933795at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06529">
        <property type="entry name" value="S24_LexA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00015">
        <property type="entry name" value="LexA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006200">
        <property type="entry name" value="LexA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039418">
        <property type="entry name" value="LexA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006199">
        <property type="entry name" value="LexA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006197">
        <property type="entry name" value="Peptidase_S24_LexA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015927">
        <property type="entry name" value="Peptidase_S24_S26A/B/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01726">
        <property type="entry name" value="LexA_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00717">
        <property type="entry name" value="Peptidase_S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00726">
        <property type="entry name" value="LEXASERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00498">
        <property type="entry name" value="lexA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12 13" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="4 12" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 12 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 12" id="KW-0678">Repressor</keyword>
    <keyword evidence="11 12" id="KW-0742">SOS response</keyword>
    <keyword evidence="9 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 12" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="LexA_DNA_bind" evidence="15">
        <location>
            <begin position="2"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S24" evidence="14">
        <location>
            <begin position="96"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="12">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="active site" description="For autocatalytic cleavage activity" evidence="12">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <feature type="active site" description="For autocatalytic cleavage activity" evidence="12">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="12">
        <location>
            <begin position="103"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ALN58551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OPD64224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="QCW28784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ROU06738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="220" mass="24032" checksum="D8C2DEDAEA631D0E" modified="2016-02-17" version="1">MSLTDTQQAILALIAERIDAEGFPPSQTEIARAFGFKGVRAAQYHLEALEAAGAIERLPGRARGIRVLQPPPQAQRELGLVAAPAQSFDEDALRLPVLGRVAAGAPIGSAAGIEPDNYVLLDRNMFFPSPDYLLKVKGDSMRDEGIFDGDLIGVHRTRDARSGQIVVARIDDEITVKLLKIGKDRIRLLPRNPDYAPIEVQPDQDFAIEGLYCGLVRPNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIR6</accession>
    <name>A0A0S2DIR6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Secretion protein HlyD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_3237</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948144.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3237"/>
    <dbReference type="EnsemblBacteria" id="ALN58583">
        <property type="protein sequence ID" value="ALN58583"/>
        <property type="gene ID" value="GLE_3237"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3237"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3190"/>
    <dbReference type="OMA" id="PARLEWE"/>
    <dbReference type="OrthoDB" id="1432684at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="50"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="99"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="365" mass="38160" checksum="B8916D39EBCD29A1" modified="2016-02-17" version="1">MPSTIRWFALIAVCAGLLGCAEKPDAAAADAGADASALAVSLSQARLQPVQRSVSVSGPVSAYEEMLLGVELSGQRVTALHVDVGQSVRRGQVLLELDRRTLDSELAQAQASLKQAQASLTLAQVNYDRGAKLAATQLISASSLDELRATRVQAEAQVATARASRDAAGLRRDFAELRAPADGVVSKRLVQPGQVVSAGAELLRLIRDGRLEWRAELSEAQLADVGVGDPVELAYGARSVAGRIRAVSPGVDAQTRTGTVYADLPQPGPLKPGVFVEGRIVTGDGQALMVPTAAVVQRDGHSYVFTMKDAHSVQRRRVGTGQTARGDIEIVDGLKPGERVVSGGAGFLGDGDRVRVVPAAAERAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ12</accession>
    <name>A0A0S2DJ12_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Trypsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948006.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3050"/>
    <dbReference type="EnsemblBacteria" id="ALN58397">
        <property type="protein sequence ID" value="ALN58397"/>
        <property type="gene ID" value="GLE_3050"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3050"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3010"/>
    <dbReference type="OMA" id="RINMWVE"/>
    <dbReference type="OrthoDB" id="741829at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595673" evidence="1">
        <location>
            <begin position="22"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="396" mass="41407" checksum="05D2FC7EFBDC4ECE" modified="2016-02-17" version="1">MRLSVSPLLLALAALALPALAAPPRNNAPVVASAAELAVYVPPSMLTSNTYLPRINMWVEPGKALGDALDEVGRRYFPALHVVPAGKDERYGLLLDLAPKWSTEGGKLTLTVAYDVYGADGKKLNSGAAEQSTALKYGNFGASAQVVTRQAVQQVMAQVQGALQPDPVKFPATGATAKIDLTALVDRSKPLRTGTAFFVNKDGQLLTAAHVARNCVAMEAHQDGATFPVKARAASDLLDVAVLDSGKPRAAALALRQGQAIELGESITSVGYPLKGVLGDSPNVTRGNVSASRGPRGSMGMFQFSAPIQPGNSGGPIVSDNGELLGVAVSTLNAESMAKLGLIPQNVNFALDGRYVAMFLQREKVPFETLRAQGAGSMQTANQAALSNTVQLNCYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ16</accession>
    <name>A0A0S2DJ16_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable lipid II flippase MurJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">mviN</name>
        <name evidence="8 11" type="synonym">murJ</name>
        <name evidence="11" type="ORF">FE772_16280</name>
        <name evidence="10" type="ORF">GLE_3289</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the MurJ/MviN family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948181.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3289"/>
    <dbReference type="EnsemblBacteria" id="ALN58635">
        <property type="protein sequence ID" value="ALN58635"/>
        <property type="gene ID" value="GLE_3289"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3289"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3240"/>
    <dbReference type="OMA" id="IFFVAFK"/>
    <dbReference type="OrthoDB" id="749401at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015648">
        <property type="term" value="F:lipid-linked peptidoglycan transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13123">
        <property type="entry name" value="MATE_MurJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02078">
        <property type="entry name" value="MurJ_MviN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004268">
        <property type="entry name" value="MurJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03023">
        <property type="entry name" value="MurJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002869">
        <property type="entry name" value="MviN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01806">
        <property type="entry name" value="VIRFACTRMVIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01695">
        <property type="entry name" value="murJ_mviN"/>
        <property type="match status" value="1"/>
    </dbReference>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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    </evidence>
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    </evidence>
    <sequence length="342" mass="37938" checksum="D5A89EBE38519C11" modified="2016-02-17" version="1">MISTEVFARRFLGYNIVGCAIRNRDLMYFIAREDYTQRPDWKSTGDDPADSALKRRVISYSRNKPEDAQWGNGVLTGFDRTDCGVSLLPREQLVVASISGQVYAVGSGEAGKETSLPRDETSRRGSLLKLKTIAGRLYMCGGNRTVAIRRGKDDWQWLTASLPFDIKTELYSAGFQDIDGFAEDDIYAAGGDGDVWHYDGARWRRIDFPTNLPLRTVCCAGDGRVYVSGYEGATFVGRGDRWRKLDAPPISLPFSDTVWHEGRVWASNDYGVWWISHDGIERADLDPAISACAGRISARDGVLLLAGFYGAAILEADGHWQTIMQYGPLAEQCEAEGRSAHP</sequence>
</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="protein sequence ID" value="ALN58828"/>
        <property type="gene ID" value="GLE_3483"/>
    </dbReference>
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    <dbReference type="PATRIC" id="fig|69.6.peg.3428"/>
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    </dbReference>
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    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
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        <property type="entry name" value="Pilin-like"/>
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        <property type="entry name" value="T2SS_protein-GspG_C"/>
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        </location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW27104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="188" mass="20444" checksum="3D2C33753486CB15" modified="2016-02-17" version="1">MNVRLRKRVVGAAVAVGSLASIVWLLHLVLGPHCTPHARVRAQVAILGEKIRAFRCDVGFLPGALSTLAAGDLPYGRYANEYDLTDSWGRALYYASDDRQGRFALFSLGRDGLPGGRDEDADIVFEGSLAPLDREIWRNRGSPVQAIDCSAYRTPPQPSLMLRQAAAAEAAKPAPRRGDDASGCRRDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK75</accession>
    <name>A0A0S2DK75_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sigma-54 dependent transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_3701</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948484.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3701"/>
    <dbReference type="EnsemblBacteria" id="ALN59045">
        <property type="protein sequence ID" value="ALN59045"/>
        <property type="gene ID" value="GLE_3701"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3701"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3645"/>
    <dbReference type="OMA" id="HNPADAV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="20"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="6">
        <location>
            <begin position="147"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="468" mass="50159" checksum="74DA21F8A8964B04" modified="2016-02-17" version="1">MPNDLAYTGTPASPAGAAPTVLIVDDDQDFARSAADFARSHGYTPYLAHSLEQSRGFAQLALMDLLLLDLDLPDGSGFELLDEDALPESGQIAIVTGYPSVETAARAVARPVMEYLVKPLVPEQFGELLDRVAARGREERSADPLGMIGRSPPMQRLGADLRRIAPSTLSVLLSGESGTGKELAARALHRLSGRGGAFVAVNCGAIAPDLLASHLFGHERGSFTGAAGRHSGYFEQAHGGTLFLDEITEMPAALQVYLLRVLESGALTRVGGAGEIAIDVRVVAACNRDPLRAVEEGALREDLYYRLADVHLELPPLRNRSGDAALIARAVLDELNAEHGARKRLAGGSERALAAHPWPGNVRELRSAVRRAFLTAPGDEVRIVPGARRLRAAAEDPATVRFSVGMSYAEIEREMLLKTLAHFGQDRTRTARALGVSVRTVHNQIARLREAGCEVDATIWTERGGPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKB6</accession>
    <name>A0A0S2DKB6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_16550</name>
        <name evidence="2" type="ORF">GLE_3350</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948230.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58696">
        <property type="protein sequence ID" value="ALN58696"/>
        <property type="gene ID" value="GLE_3350"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3350"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3300"/>
    <dbReference type="OrthoDB" id="2131476at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726575" evidence="1">
        <location>
            <begin position="25"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="154" mass="16159" checksum="C34159954704DD30" modified="2016-02-17" version="1">MSHPFSLPALAGALCLALPLAAFASPPPNANQTVPVCGYVMEMNLGFVATGTTARVLAQANLRPDGFSPPAPPPVSYTVYAAGWWRDDTHPNWEIDEDSRSGSQSFPAEPAVAGQHVFLSGSCQLKGVATVVVNCPSGPPQVRTLERTWVGCGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKB8</accession>
    <name>A0A0S2DKB8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit</fullName>
            <ecNumber evidence="2">4.1.2.40</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lacD</name>
        <name evidence="2" type="ORF">GLE_3658</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carbohydrate metabolism; D-tagatose 6-phosphate degradation; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-tagatose 6-phosphate: step 2/2.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.40" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3658"/>
    <dbReference type="EnsemblBacteria" id="ALN59002">
        <property type="protein sequence ID" value="ALN59002"/>
        <property type="gene ID" value="GLE_3658"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3658"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3602"/>
    <dbReference type="OMA" id="QRHFSYS"/>
    <dbReference type="UniPathway" id="UPA00704">
        <property type="reaction ID" value="UER00716"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009025">
        <property type="term" value="F:tagatose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001059">
        <property type="term" value="P:D-tagatose 6-phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012062">
        <property type="entry name" value="GatZ/KbaZ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08013">
        <property type="entry name" value="GatZ_KbaZ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009264">
        <property type="entry name" value="TagBP_ald_AgaZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02810">
        <property type="entry name" value="agaZ_gatZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="444" mass="48567" checksum="F2E6B096E080F729" modified="2016-02-17" version="1">MSMPPVQSLIAIHRQGHNVGLYSVCCSNELVLRAAMDVARRHDTVLLIEATSNQVDQFGGYTGMTPSQYRDYVLALARDENFPAQRLVLGGDHLGPNAWQKRPAEEAMANARTLIEAYVAAGFHKIHLDCSMSCADDPTPLPDATVAARSAELARIAERTAAAHGLPPPVYVIGTEVPVPGGEASLAGGLQVTTPQAAEQTLAIHREAFAAPDLIAAWDRVIAMVVQPGVDFDHSSVHDYDPDAARALADFLERQPRIVFEAHSTDYQREDGLHALVRDHFAILKVGPAATFAYREALFALAAIEAELLPPAQRSDLPQVLERCMLEHPRHWQQHYHGDDDELRLLRAYALSDRCRYYWGEPALVAAVQRLFDNLRAHAPPLFLLSQYLPEQYRAVRAGALANRPEALVRHRIGLCLDEYARACSANVAGPRAADGRAAAAANG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKC9</accession>
    <name>A0A0S2DKC9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glucokinase</fullName>
            <ecNumber evidence="1">2.7.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Glucose kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 3" type="primary">glk</name>
        <name evidence="4" type="ORF">FE772_18005</name>
        <name evidence="3" type="ORF">GLE_3662</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + D-glucose = ADP + D-glucose 6-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17825"/>
            <dbReference type="ChEBI" id="CHEBI:4167"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the bacterial glucokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.2" evidence="1"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948452.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3662"/>
    <dbReference type="EnsemblBacteria" id="ALN59006">
        <property type="protein sequence ID" value="ALN59006"/>
        <property type="gene ID" value="GLE_3662"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3662"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3606"/>
    <dbReference type="OMA" id="FRTHFEN"/>
    <dbReference type="OrthoDB" id="992687at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004340">
        <property type="term" value="F:glucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005536">
        <property type="term" value="F:glucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00524">
        <property type="entry name" value="Glucokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003836">
        <property type="entry name" value="Glucokinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02685">
        <property type="entry name" value="Glucokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00749">
        <property type="entry name" value="glk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="1 3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="6"/>
            <end position="11"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="328" mass="33945" checksum="1800C75E7454876F" modified="2016-02-17" version="1">MRVLVSDIGGTNARFAMAELGRGERLLRDSVREYPAAGFASAADAARHFLDELGERADAAVFAVAGRVRREEARITNHPWQIRAPDIGSALGTPRVALINDFAAQAMAISRLGADDVVAVGAAGWPGFDMDAAQTYAVIGPGTGLGVGGLLVRNGRCFALETEGGHAGFAPSRPRDMRVLECLMRRFGRVSCERLVSGPGLANLYAAVCEIEGVAARDWSPAQINAHAAGGDPRCARAVELFCAAFGSMAGDLVLTLGAWDGVFLAGGLVPKLLGALQSDSFRAAFEAKGRFAAAVAEVPALAVVHACSGLLGAAAHAAETYDSALAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKH4</accession>
    <name>A0A0S2DKH4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_3398</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0065 (bug) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948265.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3398"/>
    <dbReference type="EnsemblBacteria" id="ALN58744">
        <property type="protein sequence ID" value="ALN58744"/>
        <property type="gene ID" value="GLE_3398"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3398"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3347"/>
    <dbReference type="OrthoDB" id="447734at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005064">
        <property type="entry name" value="BUG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042100">
        <property type="entry name" value="Bug_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032774">
        <property type="entry name" value="WG_beta_rep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42928">
        <property type="entry name" value="PTHR42928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03401">
        <property type="entry name" value="TctC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14903">
        <property type="entry name" value="WG_beta_rep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595298" evidence="3">
        <location>
            <begin position="23"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="159"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="694"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="735" mass="79463" checksum="79015F7D8E392A9D" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKW8</accession>
    <name>A0A0S2DKW8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3853</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59196">
        <property type="protein sequence ID" value="ALN59196"/>
        <property type="gene ID" value="GLE_3853"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3853"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3793"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="43" mass="4540" checksum="0C33BB536348398A" modified="2016-02-17" version="1">MPRRGVSTRGGLAATSLFAHPASTLFVYGLVAARSAITRYVCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL38</accession>
    <name>A0A0S2DL38_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_18975</name>
        <name evidence="2" type="ORF">GLE_3861</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948602.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3861"/>
    <dbReference type="EnsemblBacteria" id="ALN59204">
        <property type="protein sequence ID" value="ALN59204"/>
        <property type="gene ID" value="GLE_3861"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3861"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3800"/>
    <dbReference type="OMA" id="WIVMNLI"/>
    <dbReference type="OrthoDB" id="1970605at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="168" mass="17837" checksum="FB0A7155401988FF" modified="2016-02-17" version="1">MTAALRSARSLPLWTLIGGLIAAILDIGYAIGYWGLTKGVPAERVLHSVASGLIGREAALAGGVGTAALGLFLHCFIAVLMAAAYAIGASRLAWMRRSPWRAATLYGLWLFVAMNFIVVPLSRAGMKGLPPDPVWIGLSILVHVVFVAWPIAWAVNRALNAKGGRHAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL53</accession>
    <name>A0A0S2DL53_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Type IV pilus assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pilJ</name>
        <name evidence="7" type="ORF">GLE_3959</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3959"/>
    <dbReference type="EnsemblBacteria" id="ALN59301">
        <property type="protein sequence ID" value="ALN59301"/>
        <property type="gene ID" value="GLE_3959"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3959"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3896"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
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        <property type="entry name" value="HAMP_dom"/>
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    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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            <end position="35"/>
        </location>
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        <location>
            <begin position="301"/>
            <end position="325"/>
        </location>
    </feature>
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        <location>
            <begin position="346"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="394"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="668" mass="69608" checksum="D6FC4729AE9C2338" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL57</accession>
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            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="2" type="ORF">GLE_3826</name>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_3826"/>
    <dbReference type="EnsemblBacteria" id="ALN59169">
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        <property type="gene ID" value="GLE_3826"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61481">
        <property type="protein sequence ID" value="OPD61481"/>
        <property type="gene ID" value="BV903_23435"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3826"/>
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    <dbReference type="OMA" id="YQQSNQW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="entry name" value="DUF2145"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <begin position="1"/>
            <end position="28"/>
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    <feature type="chain" id="PRO_5006595782" evidence="1">
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            <begin position="29"/>
            <end position="278"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="278" mass="29754" checksum="CF7A9B217B1186EE" modified="2016-02-17" version="1">MASTAFGRTLAAAMLAATLGLLPAQGRAGTGCGNEPLAPRKLADAAQTALIVADALDRRDAPLALVARVGSDLSAQGLVYSHVGFVVRDHPAGRWTAVHLLNECGSDRSNLYSQGLVNFFADDLVNQDARIVWLEPELAQRLAERLRALPSGALHQPHYNLIARPGSADYQNSTAWVLETLGAALTQAQAPSRNAAFAAAQRDGFRADRVHIPYSKRVLGGLFSANVAFTDHPISTRLGGDYPVVTVRSIVEYLDRSGHVQAQSEWRNGRAMRTPGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL66</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="2" type="ORF">GLE_3980</name>
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    <organism evidence="2 4">
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_3980"/>
    <dbReference type="EnsemblBacteria" id="ALN59322">
        <property type="protein sequence ID" value="ALN59322"/>
        <property type="gene ID" value="GLE_3980"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3980"/>
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    <dbReference type="OrthoDB" id="1751290at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242333" evidence="1">
        <location>
            <begin position="29"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="169" mass="18295" checksum="E4EE91345A24E5DC" modified="2016-02-17" version="1">MRVLSPSALAGSLALAVSFAVLAPAAHAAERHYVPLQQRLSAEQLKATGLDTLSPQQIQLLDQLLAQDQDAQVQEAVKKIRAERRGLPEEAAAREPVVAQLKDGAFRGWSVGTVLELENGQRWRVIEGSLYLGKPLAAPKVTIAPGMVGSTWYLQVEGQSPKAKVRRVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL87</accession>
    <name>A0A0S2DL87_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GntR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3858</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
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        <property type="protein sequence ID" value="ALN59201.1"/>
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        <property type="gene ID" value="GLE_3858"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3858"/>
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    <dbReference type="OMA" id="VEEPSYW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
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        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Aminotransferase_I/II"/>
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    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
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        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
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        <property type="entry name" value="WH-like_DNA-bd_sf"/>
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        <property type="entry name" value="WH_DNA-bd_sf"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="518" mass="56649" checksum="3084A358049AE7C5" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLB6</accession>
    <name>A0A0S2DLB6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3890</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3890"/>
    <dbReference type="EnsemblBacteria" id="ALN59233">
        <property type="protein sequence ID" value="ALN59233"/>
        <property type="gene ID" value="GLE_3890"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3890"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3829"/>
    <dbReference type="OMA" id="PFLWYVL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021102">
        <property type="entry name" value="PNGase_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31104">
        <property type="entry name" value="PTHR31104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12222">
        <property type="entry name" value="PNGaseA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595388" evidence="2">
        <location>
            <begin position="46"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="514"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="565" mass="61772" checksum="984E8A614DBC31BE" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLI0</accession>
    <name>A0A0S2DLI0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10">3,4-dihydroxy-2-butanone 4-phosphate synthase</fullName>
            <shortName evidence="10">DHBP synthase</shortName>
            <ecNumber evidence="6 10">4.1.99.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10 13" type="primary">ribB</name>
        <name evidence="13" type="ORF">GLE_4152</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18457"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="4.1.99.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="10">Binds 2 divalent metal cations per subunit. Magnesium or manganese.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Cofactor biosynthesis; riboflavin biosynthesis; 2-hydroxy-3-oxobutyl phosphate from D-ribulose 5-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DHBP synthase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the C-terminal section; belongs to the GTP cyclohydrolase II family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the DHBP synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.12" evidence="6 10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948828.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4152"/>
    <dbReference type="EnsemblBacteria" id="ALN59494">
        <property type="protein sequence ID" value="ALN59494"/>
        <property type="gene ID" value="GLE_4152"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4152"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4094"/>
    <dbReference type="OMA" id="GGVHMAM"/>
    <dbReference type="OrthoDB" id="900513at2"/>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00399"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008686">
        <property type="term" value="F:3,4-dihydroxy-2-butanone-4-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10990">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00180">
        <property type="entry name" value="RibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000422">
        <property type="entry name" value="DHBP_synthase_RibB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032677">
        <property type="entry name" value="GTP_cyclohydro_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036144">
        <property type="entry name" value="RibA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00926">
        <property type="entry name" value="DHBP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00925">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142695">
        <property type="entry name" value="SSF142695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00506">
        <property type="entry name" value="ribB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0686">Riboflavin biosynthesis</keyword>
    <feature type="domain" description="GTP_cyclohydro2" evidence="12">
        <location>
            <begin position="208"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="D-ribulose 5-phosphate binding" evidence="10">
        <location>
            <begin position="27"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="D-ribulose 5-phosphate binding" evidence="10">
        <location>
            <begin position="140"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="309"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="28"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>D-ribulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Essential for catalytic activity" evidence="10">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="site" description="Essential for catalytic activity" evidence="10">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN59494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="386" mass="41719" checksum="3764460818A73124" modified="2016-02-17" version="1">MSFATVPELLEEIRAGRMVVIVDDEDRENEGDLIMAAELVRPADINFMVTHARGLVCLSLMRERCLQLGLGPMVRDNTSPHHTNFTVSIEAAEGVTTGISAYDRAHTVRTAVRPDAKPSDLAQPGHIFPLMSQPGGVLSRAGHTEAASDLAMLAGLEPAGVLVEVLNPDGSMARRPELEQFAAEHGLKIGSIEELIRYRLATEHTVERVDAREIETEHGPFQLLSYRDRLTRAVHFALQRGEADSDAPTLVRVHVQNPLADALHWRRPDFGPAVGDVLAAIAREGRGALVLLSDHADPDALLARVREQPGAHEPHAAEHDEAPAAAVPPPTRGHALAEWRRNGAGGQILADLGLGKLRVLGTPRKQIGLAGFGLEVVEYVDIARLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLL2</accession>
    <name>A0A0S2DLL2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_16090</name>
        <name evidence="2" type="ORF">GLE_3870</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000042">
        <property type="protein sequence ID" value="OPD62911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948609.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000042.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3870"/>
    <dbReference type="EnsemblBacteria" id="ALN59213">
        <property type="protein sequence ID" value="ALN59213"/>
        <property type="gene ID" value="GLE_3870"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62911">
        <property type="protein sequence ID" value="OPD62911"/>
        <property type="gene ID" value="BV903_16090"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3870"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3809"/>
    <dbReference type="OMA" id="QNRYFEA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012434">
        <property type="entry name" value="DUF1631"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07793">
        <property type="entry name" value="DUF1631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="743" mass="81787" checksum="8076167B36646252" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLL7</accession>
    <name>A0A0S2DLL7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cell division coordinator CpoB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ybgF</name>
        <name evidence="1" type="synonym">cpoB</name>
        <name evidence="7" type="ORF">FE772_19885</name>
        <name evidence="6" type="ORF">GLE_4050</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CpoB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4050"/>
    <dbReference type="EnsemblBacteria" id="ALN59392">
        <property type="protein sequence ID" value="ALN59392"/>
        <property type="gene ID" value="GLE_4050"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4050"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3993"/>
    <dbReference type="OMA" id="YWLGEVN"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070206">
        <property type="term" value="P:protein trimerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02066">
        <property type="entry name" value="CpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039565">
        <property type="entry name" value="BamD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034706">
        <property type="entry name" value="CpoB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014162">
        <property type="entry name" value="CpoB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032519">
        <property type="entry name" value="YbgF_tri"/>
    </dbReference>
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        <property type="entry name" value="TolA_bind_tri"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="YfiO"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02795">
        <property type="entry name" value="tol_pal_ybgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="1" id="KW-0132">Cell division</keyword>
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    <keyword evidence="1" id="KW-0574">Periplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5034831186" description="Cell division coordinator CpoB" evidence="1">
        <location>
            <begin position="28"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="TolA_bind_tri" evidence="5">
        <location>
            <begin position="31"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="YfiO" evidence="4">
        <location>
            <begin position="143"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="181"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="101"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="49"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW27564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="271" mass="29177" checksum="9BFEBBAEC681BAC8" modified="2016-02-17" version="1" precursor="true">MLKSAERKFVLALAVVAALAAATPAFAQRASLADRVAVLEQRASDNQANMDLLNQVNQLKSEMQALRAQVEELQQQNRQLQESGKAQYLDTDNRLNRLESGAPAAAAPGPQASAAKPSPPSPAVKDSAPSVHGDPGLLAQGGDERAAYDAAFNALKGGQYVESARLFQEFLAAHPNGTYTPNALYWLGESYYVTQNYQLAQEQFQSLLDRYPTHDKAAGALLKVGLAQFGLKQVDAAERTLADVANRYPGTDAARTAADRLNAIQLSRLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLR6</accession>
    <name>A0A0S2DLR6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3987</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59329">
        <property type="protein sequence ID" value="ALN59329"/>
        <property type="gene ID" value="GLE_3987"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3987"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3924"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="275" mass="29954" checksum="1D1FF631391E3A48" modified="2016-02-17" version="1">MILVEGVLRELHLGECREDLLQKIDGHYRGKSALAGASAGAGDLFGQAANAAMLAMCDGEAAQNFACIIDGQVVCGQFAGAQLLKEGNCVRIAAERNGDAIVACGILDEKQGLVWVEHPWGGAAEMLANWKIALWCFGFAYVPLTLLSWFQGAGSWSFWEFQLFIVAALVLLCGGLALWANKGMRTLSARSTEVFRLLGFSSPERVNLNKYQVSLVESRKRMKLISAKRKELREGTFTLPPKVPILNVSSEQLRNTHDYKQAIEDGKLSMASVGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM21</accession>
    <name>A0A0S2DM21_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">General secretion pathway protein F</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="13">Type II secretion system F family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="12">Type II secretion system protein GspF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">gspF</name>
        <name evidence="12" type="ORF">BV903_07840</name>
        <name evidence="13" type="ORF">FE772_20510</name>
        <name evidence="11" type="ORF">GLE_4181</name>
    </gene>
    <organism evidence="11 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">C3</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">B25</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the GSP F family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000015">
        <property type="protein sequence ID" value="OPD64559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948850.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4181"/>
    <dbReference type="EnsemblBacteria" id="ALN59523">
        <property type="protein sequence ID" value="ALN59523"/>
        <property type="gene ID" value="GLE_4181"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64559">
        <property type="protein sequence ID" value="OPD64559"/>
        <property type="gene ID" value="BV903_07840"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4181"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4123"/>
    <dbReference type="OMA" id="YVVPQFV"/>
    <dbReference type="OrthoDB" id="1596769at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003004">
        <property type="entry name" value="GspF/PilC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001992">
        <property type="entry name" value="T2SS_GspF/T4SS_PilC_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30012">
        <property type="entry name" value="PTHR30012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00812">
        <property type="entry name" value="BCTERIALGSPF"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00874">
        <property type="entry name" value="T2SP_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="213"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="371"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="10">
        <location>
            <begin position="71"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="10">
        <location>
            <begin position="275"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN59523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OPD64559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW27662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="405" mass="43945" checksum="5B2DD72C4F60FE1D" modified="2016-02-17" version="1">MPLYRYQALNARGELLDGQMEAGGVAEVVARLQEQGHLPVDTRLASEGGGGSSWRGLFKPKPFTGARLVQFTQQLSTLLGAGQPLDRALTILLDLPEDEAAKSTVADIRDAVRGGTSLSVALERQHGTFSRLYINMVRAGEAGGNLHDTLARLDDYLERSRQMQGRVINALIYPAILLLMVGASLLFLLGYVVPQFGAMYESLDAELPMFTQVVLWAGTFVRDWWIVLIAVPALALLWFDRKRRDPAFREALDEWLLKRKFVGPLIGKIETARLARTLGTLVRNGVPLMTAIGIGRNVLNNRVLAADVDAAAEEVKNGVALSTALAKGKRFPRLALQMIQVGEESGALDAMLMKTAETFEQDTGMALDRMLAALVPVVTVALAGIVGTVVMAVLLPLYDLTNAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMB0</accession>
    <name>A0A0S2DMB0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4526</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949122.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59867">
        <property type="protein sequence ID" value="ALN59867"/>
        <property type="gene ID" value="GLE_4526"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4526"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4462"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595253" evidence="1">
        <location>
            <begin position="29"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="430" mass="45551" checksum="9E80A03F7D077BA3" modified="2016-02-17" version="1">MTAENGISTRARRLWPLLPLAAAALAPAAAQPPDCGAKAEIALICRQAPDGRKASLVRTELPARGGCERPLLETFTDSDRDRPRSLALAVGQSGECRFADGGSLRVRVQAGPPPPAGPCSGQPSASFSLWLDDRRVADRREVRSRCESAPAPWTYRVDGDAVYDCSNGDCGPLLAQDQALAALPVDAGEFPDAAAAATAQAAAQAAAAPNGLQRLLDRGPVCAEAERQLALSWDAFDPFRRGDDADAPLHRVAASEAPAGTAMPDALAFAHGAWRAFDFDFDNDGLIDRVYLGDARDEGEWYASPLLVVPGASAQQFQARAGAAAAQAVPCQWDGARPPLSHCDDLRSPAWSRRQPLQQAVPAPLPGLPGGDAFFQTRTTTALPLRYEDATYVALRSSAGSARDYVALYRPKPGGGREAVCLIQRRPDAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMJ3</accession>
    <name>A0A0S2DMJ3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4493</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949097.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59834">
        <property type="protein sequence ID" value="ALN59834"/>
        <property type="gene ID" value="GLE_4493"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4493"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4430"/>
    <dbReference type="OMA" id="DRITMET"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007497">
        <property type="entry name" value="DUF541"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04402">
        <property type="entry name" value="SIMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="228" mass="24451" checksum="0AF263F2D1A87246" modified="2016-02-17" version="1">MSTPPDRIETLVTRDAWVKPIGITLQVHVVGTALVGSMAAVRKSKELVAIQDLMRGLGVGDDKIRIDSLTFAAGERWFSGSSVEIDLEIRDVPAQSVPEALGGLASLKGVSLRGMRREYGALSAERDELLRAAVAESMRQARLIADAAGLRLRSVHSLSQQWGEPNDDNDHAYPMARGARAKLSVSADDMKGYQLVENHEGKLSLTVRMELRVGEFGEAAGGTESGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DML0</accession>
    <name>A0A0S2DML0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59609">
        <property type="protein sequence ID" value="ALN59609"/>
        <property type="gene ID" value="GLE_4268"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4268"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4206"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="61" mass="6992" checksum="F880F3A71D93FD6D" modified="2016-02-17" version="1">MWEGLQPRCSYVRSPRPERKASGLKALPRQAFRKRPVVRIQLQPIRSPPQAAAISLLWEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMQ3</accession>
    <name>A0A0S2DMQ3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AsnC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_4388</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4388"/>
    <dbReference type="EnsemblBacteria" id="ALN59729">
        <property type="protein sequence ID" value="ALN59729"/>
        <property type="gene ID" value="GLE_4388"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4388"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4327"/>
    <dbReference type="OMA" id="RLIFQQW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="6"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="161" mass="18138" checksum="A04CF039037817EB" modified="2016-02-17" version="1">MAAMKLDRFDRRLLNLVQDDADQTAERLAEQVALSPSAIQRRLRRLREAGVIQRHAAVLDPRQVGKPTFFLVSLQVERERPELLAQLRRWLAECAQVQQAFYVTGEADFVLVVATPDTEAFDALMLRLVAENPNVRRFTTNVALSLVKRGLAIAVAEDGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMS9</accession>
    <name>A0A0S2DMS9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HAD family hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">NLI interacting factor-like phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_21860</name>
        <name evidence="2" type="ORF">GLE_4479</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4479"/>
    <dbReference type="EnsemblBacteria" id="ALN59820">
        <property type="protein sequence ID" value="ALN59820"/>
        <property type="gene ID" value="GLE_4479"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4479"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4416"/>
    <dbReference type="OMA" id="DETLWHG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="1">
        <location>
            <begin position="9"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="196" mass="22481" checksum="1B41486F2D03263B" modified="2016-02-17" version="1">MTGDRPAPPSGDRLALMLDLDETLIHASDVELDRAADFRALGYHVYRRPHLQAFLDHVLARYDIGVWTSSGRLYAEAVCAELFPPQSLRFLWASERCSLSRDWNTGEHLYRKRLQKLKTHGYRLERLIAIDDTPSKHAQNYGNLVCVSEYRGEDAHDDELLRLMPYLDALAGEANVRGIEKRRWRERVAAAGPRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMV6</accession>
    <name>A0A0S2DMV6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4549</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59890">
        <property type="protein sequence ID" value="ALN59890"/>
        <property type="gene ID" value="GLE_4549"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4549"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4485"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="54" mass="5678" checksum="102F542B7B51E7B6" modified="2016-02-17" version="1">MIFTFSFAPAALTGRGPWYRLPPGVGAAGLEIESDQCTACVTESCPMRTSVAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMY4</accession>
    <name>A0A0S2DMY4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-binding response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Response regulator transcription factor</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BV903_14020</name>
        <name evidence="8" type="ORF">D9T17_06410</name>
        <name evidence="7" type="ORF">FE772_22355</name>
        <name evidence="5" type="ORF">GLE_4581</name>
    </gene>
    <organism evidence="5 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 9">C3</strain>
        </source>
    </reference>
    <reference evidence="6 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">OH11</strain>
        </source>
    </reference>
    <reference evidence="7 12" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 12">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000036">
        <property type="protein sequence ID" value="OPD63250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000019">
        <property type="protein sequence ID" value="ROU07832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_RCTY01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4581"/>
    <dbReference type="EnsemblBacteria" id="ALN59922">
        <property type="protein sequence ID" value="ALN59922"/>
        <property type="gene ID" value="GLE_4581"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63250">
        <property type="protein sequence ID" value="OPD63250"/>
        <property type="gene ID" value="BV903_14020"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4581"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4517"/>
    <dbReference type="OMA" id="DHQVVRR"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CheY-like_superfamily"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RESPONSE_REGULATORY"/>
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    </dbReference>
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    <keyword evidence="1 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="4"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="145"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD63250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW27979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROU07832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="219" mass="23727" checksum="C8A15160BDF02EC7" modified="2016-02-17" version="1">MSTSVLLVDDHEVVRKGIRSLLALTDDFEVVGEAAGGAEAIERARDLAPDLIVIDLMMPDVDGVEAIRAIKKLSPRSAIAVLTSTDQDDLAFAAIEAGAQSLLFKSMLGDELLTTLRRIAGGEAVIHPFVAQRILKAVRRKREPREDPFASLTERELDVLRKLAEGGSNARIAAALNIGEKTVKSHLGNVLAKLHLADRTEAVAFAWRRGLMSGERDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN82</accession>
    <name>A0A0S2DN82_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4701</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4701"/>
    <dbReference type="EnsemblBacteria" id="ALN60042">
        <property type="protein sequence ID" value="ALN60042"/>
        <property type="gene ID" value="GLE_4701"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4701"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4635"/>
    <dbReference type="OMA" id="WNWDTGG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="191" mass="21704" checksum="4B245EA9E870EB88" modified="2016-02-17" version="1">MVRPIPRAPPMLPDNESDYEDDGHDFAGDDGEDLDDEALVWQLLLLINPGDEDTALQQFARYREAREESGDEDEPVDTVREAIDWTSGFHVDWKDTPSFVDVIDQLAARWNLRIDWGVEDPSDEDFLDGVDVPELMAIAYDRLREHGYTLWNYDTGGDAYAGWIALRRDDENMKAVARGLGIDVQPANEAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNV9</accession>
    <name>A0A0S2DNV9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integral membrane protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Stage II sporulation protein M</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_24255</name>
        <name evidence="2" type="ORF">GLE_5002</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW28295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949477.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5002"/>
    <dbReference type="EnsemblBacteria" id="ALN60343">
        <property type="protein sequence ID" value="ALN60343"/>
        <property type="gene ID" value="GLE_5002"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5002"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4930"/>
    <dbReference type="OMA" id="QVWTNNA"/>
    <dbReference type="OrthoDB" id="1745181at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002798">
        <property type="entry name" value="SpoIIM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01944">
        <property type="entry name" value="SpoIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="304"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="337" mass="37529" checksum="C0115D5B39906078" modified="2016-02-17" version="1">MKQERFVERHQAEWREFELWLERRSDSARRARSTRREWSGIRDDEMPARHRRLCQQLALARRRGYSAVVTDRLQQLMQRGHSVLYRTKPAHPRRAVEFLLAGFPRLVRAEWRCMLAAALLFLVPLVSIFVAIQVKPDLASGLFPPQMLAQFEQMYDPASKRSLGRTNEDDLQMFAHYIGNNVGIGFQTFATGLVAGVGTVFVLIFNGIMIGGVAGHLQAVGHGDPFWRFVAGHSAPELTAIVIAGGAGLRMGLSLIAPGQRRRVDSLIHGGRRGAKICIGVFAMLVFAAFVEAFWSSIANMPASIKYAVGALLWALTALWLLRGGRNAAHQDDEDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP73</accession>
    <name>A0A0S2DP73_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Acyltransferase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_24695</name>
        <name evidence="3" type="ORF">GLE_5097</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949551.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60438">
        <property type="protein sequence ID" value="ALN60438"/>
        <property type="gene ID" value="GLE_5097"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5097"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5022"/>
    <dbReference type="OMA" id="DFVQSWS"/>
    <dbReference type="OrthoDB" id="1968136at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="321"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl_transf_3" evidence="2">
        <location>
            <begin position="5"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="370" mass="41131" checksum="1BF1E2B0027962BF" modified="2016-02-17" version="1">MSRLPGLDLLRAIAIVWVMFFHAAGQGLGSPWMPMSQFGWMGVDLFFALSGYLIGWQVLRPLSEGRRLDFKDFYLRRALRVLPAFWTVLALYLLWPAFRERPGLESGWQFFSFTLNLLIDYERNKAFSHAWSLCVEEHFYLLFPLLAIALTRRPALWKGVAAVIALALAGIALRAWVWNGLDDNANHWVERIYYPTWMRLDGLLFGVALAALRAYRPRAWAAMMRRSGWLALAGVAVLAAAMWISRERLGFAASVFGFPLISLAMALVVAAGASEQRWTGRLRIPGAGWLAAASFSLYLVHKGMFALMAGAFGEALDARPLLAFCAYAAAALAGGALLHYSVERPFLRLRDGLIRSRRATSPTASEAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPF0</accession>
    <name>A0A0S2DPF0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5087</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60428">
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        <property type="gene ID" value="GLE_5087"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5087"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5014"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046116">
        <property type="entry name" value="DUF6053"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19523">
        <property type="entry name" value="DUF6053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="56" mass="5668" checksum="D5889ED5087D829D" modified="2016-02-17" version="1">MNFMVVVLVAAGGAPTLTERRTGTAGIDMAGRKAAWAHAVVGGPSGPMLLFRIAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPN1</accession>
    <name>A0A0S2DPN1_LYSEN</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">FE772_24600</name>
        <name evidence="1" type="ORF">GLE_5075</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN60416">
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        <property type="gene ID" value="GLE_5075"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5075"/>
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    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="162" mass="17762" checksum="7F423EF8B96624F8" modified="2016-02-17" version="1">MQQAIRLAGFFAAHGVWCVADGEDLIPLYAFEDPAGERKMVRYAGEQVEDAVAEARARLAANPDGAQHAVLVHDGFLTLPSGRTDALILSVRDFAGEGALTLAVPYRNAAHPLGFAVHRPKFLDWRGEQEPDYGQLGEDFFAGVEEHEMGDRVWQAQLDDSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPN7</accession>
    <name>A0A0S2DPN7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LysM peptidoglycan-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_24540</name>
        <name evidence="2" type="ORF">GLE_5062</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949525.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60403">
        <property type="protein sequence ID" value="ALN60403"/>
        <property type="gene ID" value="GLE_5062"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5062"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4990"/>
    <dbReference type="OMA" id="MSYRIDI"/>
    <dbReference type="OrthoDB" id="2105123at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="1">
        <location>
            <begin position="27"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="884" mass="94227" checksum="57A8DD3F85D4F8EB" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPT1</accession>
    <name>A0A0S2DPT1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Cell division protein FtsX</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FE772_23850</name>
        <name evidence="13" type="ORF">GLE_4914</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">C3</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the ABC transporter FtsEX involved in cellular division.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Forms a membrane-associated complex with FtsE.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4914"/>
    <dbReference type="EnsemblBacteria" id="ALN60255">
        <property type="protein sequence ID" value="ALN60255"/>
        <property type="gene ID" value="GLE_4914"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4914"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4844"/>
    <dbReference type="OMA" id="ETGIMRL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004513">
        <property type="entry name" value="ABC_transpt_FtsX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040690">
        <property type="entry name" value="FtsX_ECD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47755">
        <property type="entry name" value="PTHR47755"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18075">
        <property type="entry name" value="FtsX_ECD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003097">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9" id="KW-0132">Cell division</keyword>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="319"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX_ECD" evidence="12">
        <location>
            <begin position="112"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR003097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF18075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN60255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW28231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="350" mass="37649" checksum="B9BD5234D17CD49A" modified="2016-02-17" version="1">MSAEDFRPDEDGASERVADKRADVSRADLRPSELRAERAELAVDASAQSRLGMWLDHHLYSLVASLGRLLRKPWAALLTIGVMAVALALPLGLWAALSNIERFAGDVQRSRQISVFLKPQIEVDRARALAEQLRARPDVGAVDVRTPEQGLAELREKSGLAEALAAVENNPLPSLLVVTPKGDELVLAQSLEQLGEADVVQHDAGWRQRLDGWLRFGTRLAWVLAAMLGLGALLVVGNTVRLDIQSRREEIGVLQQLGATDGFIRRPFLYLGACYGLAAGAVALALLTAADHSLREPLGALARSYGSRFALRGFDPLQALGILAGAAALGWLGAGVVTGHYLRQTRGGQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQA2</accession>
    <name>A0A0S2DQA2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hupA</name>
        <name evidence="5" type="ORF">BV903_05290</name>
        <name evidence="7" type="ORF">D9T17_02815</name>
        <name evidence="6" type="ORF">FE772_00355</name>
        <name evidence="4" type="ORF">GLE_5418</name>
    </gene>
    <organism evidence="4 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 8">C3</strain>
        </source>
    </reference>
    <reference evidence="5 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">OH11</strain>
        </source>
    </reference>
    <reference evidence="6 11" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 11">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000010">
        <property type="protein sequence ID" value="OPD64910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000008">
        <property type="protein sequence ID" value="ROU08737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949797.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000008.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5418"/>
    <dbReference type="EnsemblBacteria" id="ALN60759">
        <property type="protein sequence ID" value="ALN60759"/>
        <property type="gene ID" value="GLE_5418"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64910">
        <property type="protein sequence ID" value="OPD64910"/>
        <property type="gene ID" value="BV903_05290"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5418"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5334"/>
    <dbReference type="OMA" id="HLETTII"/>
    <dbReference type="OrthoDB" id="1847472at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD64910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW28553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROU08737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="127" mass="13182" checksum="E93B5A61CB110E4F" modified="2016-02-17" version="1">MATKKTAAKKKAAPKAAAKTAAPKPIKEVLSKSGLVAHLAETTGVVAKDVRSILGALEGAVHASINKKGAGAFTLPGILKITAVSVPAKPKRKGINPFTKEEQWFAAKPATVKVKVRPLKKLKDAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQB6</accession>
    <name>A0A0S2DQB6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">amt</name>
        <name evidence="11" type="ORF">GLE_5138</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5138"/>
    <dbReference type="EnsemblBacteria" id="ALN60479">
        <property type="protein sequence ID" value="ALN60479"/>
        <property type="gene ID" value="GLE_5138"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5138"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5063"/>
    <dbReference type="OMA" id="MACWNSN"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="PTHR43029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595424" description="Ammonium transporter" evidence="9">
        <location>
            <begin position="43"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="340"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="373"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="416"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium_transp" evidence="10">
        <location>
            <begin position="62"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN60479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="466" mass="48025" checksum="39FC39A2102FE467" modified="2016-02-17" version="1">MKYAKMKYAKTFDDRSRERMCKTMLWTALPLAALLAFGPAHAQDAAAAAEAAKPVVDKGDVAWMLTSTLLVLLMTVPGLALFYGGLVRSKNVLSVLMQVLAVFSLIVLLWVSYGYSLAFAGGNAFIGTFDKLLLKGVDKDSLAATFTAGVALPEYVFVAFQSTFAGITGALIVGAFAERIKFAAVLLFAAIWFTFAYLPIAHMVWYGPDGYLFAKGAIDFAGGTVVHINAGIAGLVGAYFVGKRVGYGREALKPHNVTFTMIGASLLWVGWFGFNAGSNLEATSGAALAFLNTLLATAAAALAWSLVEKIAKGKSSMLGGASGVVAGLVAITPACGTVGPFGAIAIGAIAGAACVWGVHGLKRLLRADDALDVFGVHGLGGIIGALLTGVFSAPALGGFGLGAGNETIAAQVGVQALGVAITVAWSGLVSVVAFVIVKAVVGLRVAEEAEREGLDITTHGESAYEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQI7</accession>
    <name>A0A0S2DQI7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_08070</name>
        <name evidence="5" type="ORF">FE772_25250</name>
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            <authorList>
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                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Feng T."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
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    </evidence>
    <sequence length="247" mass="27574" checksum="12B922EF388DCDCC" modified="2016-02-17" version="1">MKRPSRPFAPRGLAAPALRLLALAVLAAAAPVAGAQVDQRYDPANVNSRVNNPVFQRQMRQSAQSVAESLVGRSANATDQRILGQFDQVQTQALNQMQNALDRMPQPDPRYGQPGEQELDERTIQQMQQTPEGRYVLEQVMAERRRGGGVQRYPQAQAQYPQQQQYQRAPQAQNDYDRLYQQAYPDGMQGPGQNRGGYPQPQSSTGRSLGGALLQDITNAAIQRSIGPRVQVQGNPYYYQQQQGRRP</sequence>
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</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
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        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
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        <property type="protein sequence ID" value="ALN55702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="QCW24714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_0344"/>
    <dbReference type="EnsemblBacteria" id="ALN55702">
        <property type="protein sequence ID" value="ALN55702"/>
        <property type="gene ID" value="GLE_0344"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0344"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.341"/>
    <dbReference type="OMA" id="FLMVNVM"/>
    <dbReference type="OrthoDB" id="1479518at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="231"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="99"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN55702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW24714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="310" mass="33061" checksum="09D6B02B93256C31" modified="2016-02-17" version="1">MRAAPRLLRLGGRLLEAAITLWLLGTLCFVLLRAAPGGPFDTEKAAPPEVQAVLDAQYRLDQPLLLQYLGWFGDALRGDLGPSFQYPDYTVNQLIANALPVSALNGGLALLLALLFGVGLGAWAALRAGGWTDRALMLLAGLGLAIPKFVVAPLLVLLFAVTLHWLPAGGWGEWDNVVLPVIALALPNIAYCARLTRASLLDTLSADYLRAPRARGLSETRLLFAHALKPALLPVAAWLSPALINVVTGSAVVEQVFGIPGMGRYFVQGALNRDYTLVLGVVLAIGALIVAINVLVDALRGWMDPRLEQG</sequence>
</entry>
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    <organism evidence="2 3">
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            <taxon>Bacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN55678">
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    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0320"/>
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    </dbReference>
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        <property type="entry name" value="PAAR_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05488">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="181" mass="18516" checksum="4D6784525D7D095B" modified="2016-02-17" version="1">MGDTTTGGGSVVSGSPFTDIDGKPVARIGDSVVCLRHGPTVIVSGDSSMIVDGQPVARHGDGLACTCSLVAVQQAHVHIASGGAGGAASAAAASTVAAAQEDEEVAGHDYDQHFLLVDEAGGEPLKDWPYLIELPSGKKIEGRTDAEGKTRKISSQEAELATLSVLEPEPPSLDANWDDRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB27</accession>
    <name>A0A0S2DB27_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_02750</name>
        <name evidence="3" type="ORF">GLE_0392</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
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            <begin position="1"/>
            <end position="30"/>
        </location>
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        <location>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24748.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="126" mass="14523" checksum="7ADDEE327D4BDC54" modified="2016-02-17" version="1">MFLKAGRMALLLSVAAHLFILAPYPGIARAQWHDGDRRDWNRDRNDYPREDWRQRDRERKRREEAQANGVVAGVVGAAVLATVIAAAAKRDKENRSRADYCISRYGNYNRANDTYRAADGYTYRCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB89</accession>
    <name>A0A0S2DB89_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
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        <lineage>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="GLE_0457"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0457"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.455"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="185" mass="20228" checksum="1B64690E149547F5" modified="2016-02-17" version="1">MAATGYADRVSALTELMPPKSGATYTERSYRSPLAAELTVKEAQGALDFHATVRNQGAFAWFVPTHDYFLGGSFRIYDRKGAMVAAYPVYEEAGRLKLGDDMFGELKPGQSVGIDARVTLSQVLERVEGGEFVIQFANSAVPPGLEASFMNERKELISIVLSSQRIRARCAKEGGGYRCSFSPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBA4</accession>
    <name>A0A0S2DBA4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FE772_02405</name>
        <name evidence="8" type="ORF">GLE_0319</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0319"/>
    <dbReference type="EnsemblBacteria" id="ALN55677">
        <property type="protein sequence ID" value="ALN55677"/>
        <property type="gene ID" value="GLE_0319"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0319"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.316"/>
    <dbReference type="OMA" id="SARWILN"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
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    <accession>A0A0S2DC71</accession>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Feng T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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        <source>
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    </evidence>
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</entry>
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    <accession>A0A0S2DC83</accession>
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            <fullName evidence="3">Uncharacterized protein</fullName>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="394"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="466"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="466"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="501" mass="53953" checksum="16EE674E7F740A10" modified="2016-02-17" version="1">MDLAMNESEQARRDADWTAERRELWQRLRDYRFGGDRAEAFLDRVGHALGCDRAGAEAALEEYRRFCFLAVAAGHAVTPSVRIDKVWHAHLTDTRDYWGRFCPQALQRELHHTPSLGGQAEDARHQEQYRQTLASYADFFDEPPPLWWPPPPSPAQAQARPRAEPAGARERLLSPWQSPPRGGYLALSLASGAVGLIYLTCVRAQETFNPLDFGGGGFLALYLAMLPWAYLAGTAIKRALRGPNRRNQAQVEDEVELAYLAGGPERAVDVALVELMRRDLLALDYNGAPLRAAERLDRVWLRVDAARLRAQAAQLPAPVLAAAETAQREQSLSLTVIALARAYEPMAERLRRKGWWLSESADLRLRQLGSAPLLALAALGGLKIWIGLGRDRPVGFLVVLVGLTLIVAMARLLRQQQRTRAGEWALHDASGRIAPGDLAAQVALSGTVGLYGSGFADYHILRTPPSGSSGGDSGSGSSGGDSGGGGCGGGGGGGCGGCGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCT3</accession>
    <name>A0A0S2DCT3_LYSEN</name>
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        <submittedName>
            <fullName evidence="5">RNA methyltransferase, TrmH family, group 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_0996</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0996"/>
    <dbReference type="EnsemblBacteria" id="ALN56354">
        <property type="protein sequence ID" value="ALN56354"/>
        <property type="gene ID" value="GLE_0996"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0996"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.984"/>
    <dbReference type="OMA" id="ATTHHEG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004441">
        <property type="entry name" value="rRNA_MeTrfase_TrmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013123">
        <property type="entry name" value="SpoU_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016479">
        <property type="entry name" value="YfiF_prd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46429">
        <property type="entry name" value="PTHR46429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46429:SF2">
        <property type="entry name" value="PTHR46429:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08032">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00967">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_sub_bind" evidence="4">
        <location>
            <begin position="140"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="72"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="376" mass="39678" checksum="07DB5DDB313B10CA" modified="2016-02-17" version="1">MRRDDPPRGPRKPPGSPYGAGGGQRGPGAPRGDGGPGQGGPSRQGGPGGPGAHSGQGGAGAPAGGDGQGPWRERGGSHHPHSREQRRDQRARHDEVEHDERPRGRHHERHERGYRRHDDDDQGEAGAPHPQRARRDAEIRLYGLNAVRAVFAQRPQALRKLYLDAPRIPQLQPLLAWCVANRVGYRVVESADLDKLAASGHHEGVVAEVLREEPAPLSSWLRDLPAGPQLALWLDGVGNPHNLGAILRSAAHFGVAAVLLPKDSTLALSGAAARVAEGGAEAVPMVRLGRSDNAVAQLRGAGFELAATVVGGGEDVFAAPLPPRLIYVLGAEGEGMDRELAAACDRRLSIPGTGRVESLNVAAATAVLLAAWRSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCZ3</accession>
    <name>A0A0S2DCZ3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Translation initiation factor-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_1047</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56405">
        <property type="protein sequence ID" value="ALN56405"/>
        <property type="gene ID" value="GLE_1047"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1047"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1036"/>
    <dbReference type="OMA" id="TGAAMDH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013229">
        <property type="entry name" value="PEGA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08308">
        <property type="entry name" value="PEGA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012836688" evidence="2">
        <location>
            <begin position="16"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="PEGA" evidence="3">
        <location>
            <begin position="29"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="158" mass="15916" checksum="97612625D22B1503" modified="2016-02-17" version="1">MRPIAPAAVAALALAAGGCATFIRGSTQSLTIDSLPGAATVSLSNGERCSTPCVLKLKRKHPVAVELCKPGYRQALTQVRSELGSAGAVRMAGNALIGGLIGVGVDAASGAAKDLNPNVLAVLLVEETPGCTAPAFPAVPENGQTPEEYARAKGKGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCZ8</accession>
    <name>A0A0S2DCZ8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4124 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1026</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946471.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1026"/>
    <dbReference type="EnsemblBacteria" id="ALN56384">
        <property type="protein sequence ID" value="ALN56384"/>
        <property type="gene ID" value="GLE_1026"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1026"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1014"/>
    <dbReference type="OMA" id="GCFWITL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025392">
        <property type="entry name" value="DUF4124"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13511">
        <property type="entry name" value="DUF4124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4124" evidence="2">
        <location>
            <begin position="7"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="234" mass="23666" checksum="A26407B475527DF6" modified="2016-02-17" version="1">MPPLVFAAAALSPTAASAQIHRCTDARGNSVYTDRDCAAVGGVDRLPRGNAAAAKPEAAYAGGCARNLRDLVGAITTAIDAHDGNKLAAVYHFAGMSDDQGYAVIQRLDAIAQRPLLDIAPVMGAAPEPAPPRPGPWTTLPAAAPNAALAPLPPATPPPAPATGLGRPAGMDGDPAPASDPAAVAEAPAAPAPVHRRAAPVALRLEQTLANGVTPSRTVFGLTRHFGCWWIKGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD28</accession>
    <name>A0A0S2DD28_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine biosynthesis protein HisIE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">D9T17_21665</name>
        <name evidence="3" type="ORF">FE772_05950</name>
        <name evidence="2" type="ORF">GLE_1078</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">OH11</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000055">
        <property type="protein sequence ID" value="ROU04738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946507.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000055.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56436">
        <property type="protein sequence ID" value="ALN56436"/>
        <property type="gene ID" value="GLE_1078"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1078"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1065"/>
    <dbReference type="OMA" id="KFLVMIA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROU04738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="140" mass="14629" checksum="FA6E5838F71F8F9A" modified="2016-02-17" version="1">MAVKKAAKKSAAKKATKKVAKKAGAKKVAKKATKKTAKKAVKKVAKKAVRKTAKKAAKKTAKKAVKKTAKKAAKKATKKTAKKAVKKTAKKAAKKATKKTAKKAVKKTAKKAAKKAPKKAAKRARKPKAAAMPATPAPLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDA0</accession>
    <name>A0A0S2DDA0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aspartate carbamoyltransferase</fullName>
            <ecNumber evidence="6">2.1.3.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Aspartate transcarbamylase</fullName>
            <shortName evidence="6">ATCase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 10" type="primary">pyrB</name>
        <name evidence="11" type="ORF">BV903_16330</name>
        <name evidence="12" type="ORF">FE772_06415</name>
        <name evidence="10" type="ORF">GLE_1179</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">C3</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>carbamoyl phosphate + L-aspartate = H(+) + N-carbamoyl-L-aspartate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20013"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:32814"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.2" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000043">
        <property type="protein sequence ID" value="OPD62846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946574.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1179"/>
    <dbReference type="EnsemblBacteria" id="ALN56537">
        <property type="protein sequence ID" value="ALN56537"/>
        <property type="gene ID" value="GLE_1179"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62846">
        <property type="protein sequence ID" value="OPD62846"/>
        <property type="gene ID" value="BV903_16330"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1179"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1164"/>
    <dbReference type="OMA" id="FPTEREY"/>
    <dbReference type="OrthoDB" id="1844275at2"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00116"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004070">
        <property type="term" value="F:aspartate carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00001">
        <property type="entry name" value="Asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002082">
        <property type="entry name" value="Asp_carbamoyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405:SF16">
        <property type="entry name" value="PTHR11405:SF16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00670">
        <property type="entry name" value="asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00097">
        <property type="entry name" value="CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OTCace_N" evidence="9">
        <location>
            <begin position="12"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="OTCace" evidence="8">
        <location>
            <begin position="162"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN56537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OPD62846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW25348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="311" mass="32946" checksum="DA5A7A943B9C72AE" modified="2016-02-17" version="1">MTTYVSADGGSRHLLSLRDASRDSLDALLIRAQAFAEGHYDSRALAGIAVCTLFFEPSTRTRLSFQLAAQQLGAHILNFDASTSSTSKGETALDTLKNIEAMGVRGFVIRHREDGAVAGLAAHARPGTCLVNAGDGRSSHPTQGLLDMLTLRQAKGSDFSRLRVAMVGDIKHSRVARSDLQALKALGAAEIRAVGPASLLPDDGTLDGCSVGHDLDAALEGVDAVMMLRLQRERMEEGLVASLDDYHRDYGLTAARLKRAAPDAVVMHPGPMNRGVEITDEVADGPQSLILTQVANGVAARMAVLEALLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDD9</accession>
    <name>A0A0S2DDD9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3 4">NAD-dependent epimerase/dehydratase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_06000</name>
        <name evidence="3" type="ORF">GLE_1089</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946516.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1089"/>
    <dbReference type="EnsemblBacteria" id="ALN56447">
        <property type="protein sequence ID" value="ALN56447"/>
        <property type="gene ID" value="GLE_1089"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1089"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1076"/>
    <dbReference type="OMA" id="FNRGTNK"/>
    <dbReference type="OrthoDB" id="1928091at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242551" evidence="1">
        <location>
            <begin position="28"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="Epimerase" evidence="2">
        <location>
            <begin position="37"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="375" mass="40428" checksum="808D75CB47701C46" modified="2016-02-17" version="1">MTIDRRDFLAAGAAAASLLALPGGAFAAAKPQPLKLLVLGGTGFLGPHFVEAARKRGHTLTLFNRGKTNPDKFSGEDYRDIEQLHGDRKTDLSALAGERKWDAVLDTSAYIPADVTRSAKLLAPKVRQYLLVSTISVYAKNDVPSEETSPLAVLSDPNVTEVTGETYGGLKALCEKAAEAELPGRTTVVRPGLIVGPGDNSDRFTYWPARADRGGEVLAPGSAEDPTQFIDVRDLAAFLLACIERGHVGIYNADAEPGALTMGALLRESQKAAGKKSTLTWAPADFLEAQKVAPWSDMPVWIPARGEYAGFGRTSVRKARAAGLSYRPLRDTVRDTLAWWRKLPEERRAKPKAGLSAQRESEVLAAWHAQENKGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDQ7</accession>
    <name>A0A0S2DDQ7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1385"/>
    <dbReference type="EnsemblBacteria" id="ALN56742">
        <property type="protein sequence ID" value="ALN56742"/>
        <property type="gene ID" value="GLE_1385"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1385"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1367"/>
    <dbReference type="OMA" id="SGKPWRM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="332" mass="37730" checksum="C0F6E0CE995B061D" modified="2016-02-17" version="1">MGMQVPQYWAEARLQEKFGRGHVSGRVSLTVRRFGWSDSSQSEAQAMAETRVRDAFDRILAGEKLPRNEPRVPYDAEGLPIREEIVARHGNEVITRNSYGSRCLNSPDVLFADVDFKPPPMPPWRRKQFVAAVVAGAVCGVLWHPVAGIAAFIAALILIGTIHGWWARRRDLQLGGGPEARALAPVKAFVAANPDWHLRVYRTPNGFRLLAMHRTFDPLDPQVNAFFEAIGADSYYALSCRHQHCFRARVSGKPWRMGLREHMPYRRSAWPIAEEHRPERERWVAEYERKAEGYAACRFVERLGSRDYVSATQSVQRLHDDLCSATRDLPMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDZ9</accession>
    <name>A0A0S2DDZ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_24530</name>
        <name evidence="4" type="ORF">FE772_07105</name>
        <name evidence="2" type="ORF">GLE_1329</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000095">
        <property type="protein sequence ID" value="OPD61289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946693.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000095.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56686">
        <property type="protein sequence ID" value="ALN56686"/>
        <property type="gene ID" value="GLE_1329"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61289">
        <property type="protein sequence ID" value="OPD61289"/>
        <property type="gene ID" value="BV903_24530"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1329"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1312"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046256">
        <property type="entry name" value="DUF6289"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19806">
        <property type="entry name" value="DUF6289"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595000" evidence="1">
        <location>
            <begin position="21"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="71" mass="7762" checksum="A0C543D477B319F7" modified="2016-02-17" version="1">MSKKKLVLTLGLGLTLFATAASAVFVGRGEYAAYYRNGELVGGESRDCDNNLSQWGEVTDDYDMGYWLCGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE19</accession>
    <name>A0A0S2DE19_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleotidyltransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1227</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949999.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1227"/>
    <dbReference type="EnsemblBacteria" id="ALN56584">
        <property type="protein sequence ID" value="ALN56584"/>
        <property type="gene ID" value="GLE_1227"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1227"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1212"/>
    <dbReference type="OMA" id="INHAHLG"/>
    <dbReference type="OrthoDB" id="1557977at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="239" mass="26105" checksum="07A066B2EB11E81E" modified="2016-02-17" version="1">MKALIFAAGLGERMRPLTLHTPKPLLPVGGKPLIEWHLEKLAALGVAEVVVNTSWLAERFPAALGDGSRWGLRLRYSYEGPTPLETGGGMLKALALLQEDADPQAPFLVANGDIWTDYDFAALPRAFDGDAHLLLVDNPPQHPRGDFQLDADGRVGNDGDRKLTYAGIGLYRAGLFDDWRGALGDAAGSELDPPRFSIVPLLRRAADRGRLRGSHHRGRWTDVGTPERLRELDATFVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEC6</accession>
    <name>A0A0S2DEC6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_21690</name>
        <name evidence="4" type="ORF">FE772_07835</name>
        <name evidence="2" type="ORF">GLE_1493</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000072">
        <property type="protein sequence ID" value="OPD61791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946820.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000072.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56850">
        <property type="protein sequence ID" value="ALN56850"/>
        <property type="gene ID" value="GLE_1493"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61791">
        <property type="protein sequence ID" value="OPD61791"/>
        <property type="gene ID" value="BV903_21690"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1493"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1474"/>
    <dbReference type="OrthoDB" id="2093966at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595016" evidence="1">
        <location>
            <begin position="22"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="82" mass="8536" checksum="3FD4A8F15DFE1F41" modified="2016-02-17" version="1">MNACLRIAVLSLSVLGLAACAGTQSKSAYVEPAAVGAPQSAPLTRDEIYVAQVERIARRRGIGLVWVNPPPKRGAAVAQATH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEE9</accession>
    <name>A0A0S2DEE9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DOT1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1533</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946855.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56890">
        <property type="protein sequence ID" value="ALN56890"/>
        <property type="gene ID" value="GLE_1533"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1533"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1515"/>
    <dbReference type="OrthoDB" id="1664438at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018024">
        <property type="term" value="F:histone-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025789">
        <property type="entry name" value="DOT1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08123">
        <property type="entry name" value="DOT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DOT1" evidence="2">
        <location>
            <begin position="135"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="285" mass="30593" checksum="9BE49B9E96771C91" modified="2016-02-17" version="1">MSPTLRSLLDQFDTDPSWPSPPRWRERAQWQERIERASLGLAADAADLRARADAAQARLDAADAQWAATLRARIAAGEGARLLREWLRESPPHADGEGYDPLDALLGAVLDLAEPEGEVAAPAPQTVFYQPTPSRHLLELLARLELGADDVLIDLGSGLGHVPLLVAACTPARGVGIEHEAAYVASARLCARALGLRRTDFVHADARAADLSAGTVFYLYTPFTGDLLAQVLERLRALAARRAIRIASLGPCTQALATQPWLRALQPSWAADRIALFAAGPSLPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEH6</accession>
    <name>A0A0S2DEH6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DMT family transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Integral membrane protein DUF6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_08160</name>
        <name evidence="3" type="ORF">GLE_1565</name>
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        <name type="scientific">Lysobacter enzymogenes</name>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ALN56922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW25645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_1565"/>
    <dbReference type="EnsemblBacteria" id="ALN56922">
        <property type="protein sequence ID" value="ALN56922"/>
        <property type="gene ID" value="GLE_1565"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1565"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1545"/>
    <dbReference type="OMA" id="WSINAVV"/>
    <dbReference type="OrthoDB" id="1515911at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="EamA_dom"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
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        <location>
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            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="169"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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            <end position="229"/>
        </location>
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            <begin position="150"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="299" mass="32119" checksum="EECD2F6D4289820E" modified="2016-02-17" version="1">MHLLLPILATLIWAGNTIVSKLSAGAIEPAAISFYRWLVALLVLTPLMLPRVWKLRAQVRPYWRKLLVLAALGMVLYQSLAYFAAHSVSAMTMGLVVAAIPPMTMVIGMVLLKTRPSPGMLIGAVVSFAGLTWLLSGGHPAQLLQQGLGRGEMMMLLAAFSYALYGVLVKRWALPIPNGESLYLQVLCGTVLLLPGFALAPSVALTAHNLPLVLYAGILASTLAPWFWMHGLLRLGTDKTAVLMNLTPVFTALLAVCLLDEPLRAYHWIGGGLTLLGVAVAQALRQKPAPALRTQECAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DER5</accession>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <end position="391"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="402" mass="42899" checksum="53CA1CF41CDCD9D5" modified="2016-02-17" version="1">MSQQTEPTAGAQPPQSFADQVRGTQAKPIDKTLSRLMDDLYDQGPGIDGFKPLDAEQLRAKGIDPATLENKDSGFLARIYGDEHGHYVLAYSGTDEGKDWLTNFRQGLGFEDAQYNQAMALAREAKVAFGDEVVITGHSLGGGLAAAASITSGIPAVTFNASGVHDKTLERIGIDADAAKQEMADSGQIRRYAVKNEILTDLQEHSIPLKWAMPDAVGHKIELPDPDPQSFWQKLIPGSGIKHGVDIHYIEAVIKAQEMATPGERGHDAGRAAAATGAREAGRDALADAAHPHNGMYQQALHGLRGLPPGALEFGGEQGLRNAATHAALDAGGQGMRNIDHIIAGRDGRGFFAVEGGLDDPSHRRVFLDQQRAVSEPQHTAPVQPQTEAAPAPQESKRAVMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEW2</accession>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57109">
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        <property type="gene ID" value="GLE_1754"/>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="ALN57109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="40" mass="4088" checksum="47DCB8D75AEF569F" modified="2016-02-17" version="1">MAADALRRQLYSLRASIDPACAQAAAAGGAARILDVTTRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF84</accession>
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    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        </lineage>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="97" mass="10788" checksum="1C7C653BB5552593" modified="2016-02-17" version="1">MEWTGAMQGRIVVAFAKVLGAISVCMLAIWAWMALAPGCRFALDEWTWQGRAVPKRELCPGEFAVRPVQRDGRECLELYALKDGLPVGERCPRPDAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFA3</accession>
    <name>A0A0S2DFA3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proline--tRNA ligase</fullName>
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        </recommendedName>
        <alternativeName>
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        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">proS</name>
        <name evidence="14" type="ORF">FE772_09440</name>
        <name evidence="13" type="ORF">GLE_1842</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">C3</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro)</text>
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            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
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            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
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        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_1842"/>
    <dbReference type="EnsemblBacteria" id="ALN57194">
        <property type="protein sequence ID" value="ALN57194"/>
        <property type="gene ID" value="GLE_1842"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1842"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1813"/>
    <dbReference type="OMA" id="EVYWVTH"/>
    <dbReference type="OrthoDB" id="665824at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
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        <property type="project" value="InterPro"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="proS_fam_II"/>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="38"/>
            <end position="340"/>
        </location>
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        <source>
            <dbReference type="ARBA" id="ARBA00000857"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
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        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00029731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN57194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW25851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="447" mass="49914" checksum="D5AB8CA7B6AB6A6C" modified="2016-02-17" version="1">MRLSRYLLPTLKENPAEAQIASHRLMLRAGLIRQEAAGIYSWLPAGLRTLRKIEAIVREEMNRAGALELLMPTLQLADLWRESGRYDAYGPEMLRIRDRHERELLYGPTNEDMVTAIFRANVKSYRALPMNLYHVQWKFRDEQRPRFGVMRGREFLMKDAYSFDVDEAAARRSYQRMFVAYLRTFARMGIRAIPMRAETGPIGGDLSHEFLVLAQTGESAVYCDKAVLDLPIPGAGVDYDGDLDPIVRQWTAPYAATEDVHDFERFEREVPAERRLQTRGIEVGQVFYFGTKYSAPMKALVTGADGGDKPIHGGSYGIGVSRLLGAIIEAGHDEAGIVWPDAVAPFNVGIVNLDPGDAQIDELCAGVHGALEAMGLDALHDDTDERPGVKFARMDLLGLPWQLIVGRRGLSQGTVELKRRATGERLTLAPYDAVAHIGRCLENSGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFF3</accession>
    <name>A0A0S2DFF3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1909</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947136.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57260">
        <property type="protein sequence ID" value="ALN57260"/>
        <property type="gene ID" value="GLE_1909"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1909"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1877"/>
    <dbReference type="OMA" id="WNIWAAR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="70" mass="8085" checksum="B7DE05A6055CF92A" modified="2016-02-17" version="1">MDTHYCYFADYEILVGGRFIVWGQATLDYAPDAPGHFDPAELLDRIRRQAAHAHGVERDEVRVRNLSRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFN9</accession>
    <name>A0A0S2DFN9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Peptidase family M13</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLE_1995</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57345">
        <property type="protein sequence ID" value="ALN57345"/>
        <property type="gene ID" value="GLE_1995"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1995"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1962"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="PTHR11733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00786">
        <property type="entry name" value="NEPRILYSIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594765" evidence="8">
        <location>
            <begin position="23"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M13_N" evidence="10">
        <location>
            <begin position="40"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M13" evidence="9">
        <location>
            <begin position="470"/>
            <end position="672"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN57345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="675" mass="75198" checksum="3681D507259C079C" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFZ5</accession>
    <name>A0A0S2DFZ5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HTH type transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2123</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2123"/>
    <dbReference type="EnsemblBacteria" id="ALN57473">
        <property type="protein sequence ID" value="ALN57473"/>
        <property type="gene ID" value="GLE_2123"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2123"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2087"/>
    <dbReference type="OMA" id="VDRHWNL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041413">
        <property type="entry name" value="MLTR_LBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17765">
        <property type="entry name" value="MLTR_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="5"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="267" mass="29570" checksum="03189026DC132891" modified="2016-02-17" version="1">MGELLRQWRQRRRLTQFDLAEMAEISTRHVSFIETGRSLPSRAMLLRLADRLDVPLRERNALMTAAGLAPMYAERPLDHPAMREAYAAVELVLYAHEPHPALAVDRHWNLIQHNRALAPMLAGVADHLLARPANVLRAALHPEGMAPDILNFGEWRAHILHRLRHQIETSGDPVLEALYAELQAYPPPPGHDSAEYDPAELTGAAHVAVPCRMRTPFGELSFISTTTVFGTPMDVTLAELAIESFFPADAATAKAMREFGASLVASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG92</accession>
    <name>A0A0S2DG92_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947426.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2290"/>
    <dbReference type="EnsemblBacteria" id="ALN57639">
        <property type="protein sequence ID" value="ALN57639"/>
        <property type="gene ID" value="GLE_2290"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2290"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2255"/>
    <dbReference type="OMA" id="DGESWWN"/>
    <dbReference type="OrthoDB" id="1178576at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043737">
        <property type="entry name" value="DUF5682"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18934">
        <property type="entry name" value="DUF5682"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="803" mass="86530" checksum="062E12DC6B02FF08" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGB0</accession>
    <name>A0A0S2DGB0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF45 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2072</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2072"/>
    <dbReference type="EnsemblBacteria" id="ALN57422">
        <property type="protein sequence ID" value="ALN57422"/>
        <property type="gene ID" value="GLE_2072"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2072"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2037"/>
    <dbReference type="OMA" id="LCCYMEP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002725">
        <property type="entry name" value="YgjP-like_metallopeptidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01863">
        <property type="entry name" value="DUF45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF45" evidence="1">
        <location>
            <begin position="102"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="175" mass="20131" checksum="CF490FCCA968079C" modified="2016-02-17" version="1">MPYRARMDPLRYLRGYPPHVLTQVQALIDAGKLGETLRKRYDHAGHAVRDDKALFAYVVAIKDRYMRKADPLNKVIYDNKLHVVSQALGTHTAISRVQGGRLKAAREIRIATVFRDAPEPFLEMIAVHELAHLKHREHDKGFYQLCAHMSRGYHQLEFDLRLYLTAQETESAGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGE6</accession>
    <name>A0A0S2DGE6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Aconitate hydratase</fullName>
            <shortName evidence="10">Aconitase</shortName>
            <ecNumber evidence="10">4.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">acnA</name>
        <name evidence="14" type="ORF">FE772_11530</name>
        <name evidence="13" type="ORF">GLE_2294</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">C3</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>citrate = D-threo-isocitrate</text>
            <dbReference type="Rhea" id="RHEA:10336"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="EC" id="4.2.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <text evidence="10">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.3" evidence="10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947428.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2294"/>
    <dbReference type="EnsemblBacteria" id="ALN57643">
        <property type="protein sequence ID" value="ALN57643"/>
        <property type="gene ID" value="GLE_2294"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2294"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2259"/>
    <dbReference type="OMA" id="NGGIMQY"/>
    <dbReference type="OrthoDB" id="363064at2"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00718"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003994">
        <property type="term" value="F:aconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047780">
        <property type="term" value="F:citrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01580">
        <property type="entry name" value="AcnA_IRP_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044137">
        <property type="entry name" value="AcnA_IRP_Swivel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006249">
        <property type="entry name" value="Aconitase/IRP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11670">
        <property type="entry name" value="PTHR11670"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="SSF53732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01341">
        <property type="entry name" value="aconitase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 10" id="KW-0408">Iron</keyword>
    <keyword evidence="7 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 10 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase" evidence="11">
        <location>
            <begin position="67"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase_C" evidence="12">
        <location>
            <begin position="720"/>
            <end position="851"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN57643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW26206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="927" mass="99736" checksum="634065790E2CA0C9" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGY4</accession>
    <name>A0A0S2DGY4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoglycerate mutase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2349</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2349"/>
    <dbReference type="EnsemblBacteria" id="ALN57698">
        <property type="protein sequence ID" value="ALN57698"/>
        <property type="gene ID" value="GLE_2349"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2349"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2311"/>
    <dbReference type="OMA" id="WQIVNTS"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="251" mass="27141" checksum="59F949E533D7C0FA" modified="2016-02-17" version="1">MTTTLHLIRHGQAAFGAADYDQLSDLGREQSRLLGAALAPLAGEGDLAICGGMRRHRETAEECLAAMFVRDDMPAAARASASRAGERGIGRNAPTCDERWNEFDHVQILARHRPEYADHARLSADLRAQSDPHRAFQTLFAAAMQRWAGGEFDGDYDEPWPAFRARCAAALQAAAAQAGGARNVWIFTSGGPIAAVVQSLLDAPDAQALRLSWTLVNASHTQVHAARGGLRLSTFNGHAHLHARDGLITYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGZ0</accession>
    <name>A0A0S2DGZ0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">ABC transporter, ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BV903_01560</name>
        <name evidence="7" type="ORF">FE772_12575</name>
        <name evidence="5" type="ORF">GLE_2502</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000003">
        <property type="protein sequence ID" value="OPD65709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947587.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2502"/>
    <dbReference type="EnsemblBacteria" id="ALN57851">
        <property type="protein sequence ID" value="ALN57851"/>
        <property type="gene ID" value="GLE_2502"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65709">
        <property type="protein sequence ID" value="OPD65709"/>
        <property type="gene ID" value="BV903_01560"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2502"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2465"/>
    <dbReference type="OMA" id="WKEYGDQ"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD65709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW26372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="228" mass="24337" checksum="055AD7E200534EB5" modified="2016-02-17" version="1">MSLVSVRNLRKSYGLGANSVEVLHGVDLDVAEGEFVALMGPSGSGKSTLLNLIAGLDKPSAGELTVADARIGEMSATELARWRGRHIGFVFQLYHLMPTLTAAQNVEVPLLLSGLDAARRRRQARIALEVVGLSHRIDHKPAQLSGGQQQRVAIARAIVTDAPLLVCDEPTGDLDRASADEVLDLLGAFNREHGKTIVMVTHDPAAAARATRQLHLDKGRAVDAPATH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH19</accession>
    <name>A0A0S2DH19_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polysaccharide deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_12570</name>
        <name evidence="2" type="ORF">GLE_2501</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947586.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2501"/>
    <dbReference type="EnsemblBacteria" id="ALN57850">
        <property type="protein sequence ID" value="ALN57850"/>
        <property type="gene ID" value="GLE_2501"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2501"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2464"/>
    <dbReference type="OMA" id="GFCYPYG"/>
    <dbReference type="OrthoDB" id="635734at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="64"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="317" mass="34967" checksum="C69ADC934C8D8AAC" modified="2016-02-17" version="1">MRTDSSHGNAVILMYHRIADDGTELCVSPAEFRAHLAVLREEGCRVLPLQELTQALARGDAPPRSVAITLDDGYLDALTEAAPLLREFEYPATFFIITATLDGPAEFWWETLQRVFDHPALPAELDAELAGTQAPLPLDTAEQRRAAFDTVRRPFYAWTPQQRRERIAALLAWSGLAAADGTGPVRAMTPEELRHLDAMPGMELGAHTENHLLLPAHALPIKEQELRLCRQRLEALLGREVRSLSYPYGAFDEESVRAAQRAGFAAAVTTGNQPASAQSHPLVLPRCAVQAGDDLRARLRELFAAAPQAHHYDRSFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH88</accession>
    <name>A0A0S2DH88_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD kinase</fullName>
            <ecNumber evidence="5">2.7.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP-dependent NAD kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ppnk</name>
        <name evidence="5" type="synonym">nadK</name>
        <name evidence="7" type="ORF">BV903_25465</name>
        <name evidence="8" type="ORF">FE772_13475</name>
        <name evidence="6" type="ORF">GLE_2690</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">C3</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + NAD(+) = ADP + H(+) + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:18629"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the NAD kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.23" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000118">
        <property type="protein sequence ID" value="OPD61097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947738.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000118.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2690"/>
    <dbReference type="EnsemblBacteria" id="ALN58038">
        <property type="protein sequence ID" value="ALN58038"/>
        <property type="gene ID" value="GLE_2690"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61097">
        <property type="protein sequence ID" value="OPD61097"/>
        <property type="gene ID" value="BV903_25465"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2690"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2649"/>
    <dbReference type="OMA" id="NGIERMS"/>
    <dbReference type="OrthoDB" id="1463423at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00361">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5 6" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="45"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="117"/>
            <end position="118"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="158"/>
            <end position="163"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD61097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW26521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="259" mass="28118" checksum="A3B25DAB3B387311" modified="2016-02-17" version="1">MTATPRIAFLASHTDEAQRALADLSADHGQCEPAEADILVALGGDGFMLQTLHRHGALGKPVYGMKLGTVGFLMNQHAGGAGDLFERLAQAEPAVLRPLEMVAQTESGATFGSLAYNEVSLLRQTRQAAHLRIDLNGQTRLDELICDGVLVATPAGSTAYNFSAHGPILPLGSAVIALTPIAAFRPRRWRGALLKADTEVRFRVLDPYKRPVSATADSHEVRDVVEVTIRESRDRTVTLLFDPEHNLEERMLIEQFTSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH95</accession>
    <name>A0A0S2DH95_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">LysR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_02325</name>
        <name evidence="3" type="ORF">GLE_2409</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">B25</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000004">
        <property type="protein sequence ID" value="OPD65617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947520.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57758">
        <property type="protein sequence ID" value="ALN57758"/>
        <property type="gene ID" value="GLE_2409"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65617">
        <property type="protein sequence ID" value="OPD65617"/>
        <property type="gene ID" value="BV903_02325"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2409"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2371"/>
    <dbReference type="OMA" id="GKQPELC"/>
    <dbReference type="OrthoDB" id="1439189at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD65617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="298" mass="32637" checksum="4A26EEF833FA20CB" modified="2016-02-17" version="1">MELRHIRYFLAVAEEGNFTRAAQRLGIAQPPLSQQIRDLENEIGARLFQRVPHGAELTEAGRAFRERVRSLPEQAGAAVRQAQRAARGETGALRLGFTSSAILTPLTTQAIREFRRRYGEVELTLEESNSAHLSAKLRDGSLDLAFLRHDGSENEGVLLHALLEEPMIAALPLGHAAVRDGRRKSVRLEELREDALILTPRNVGPTLHEAILGACRRAGFEPRIGQHAPQLASSLALVAAELGVAIVPEAMRRFALPGIVYRDIAGLQPIARLALAQLPELDSAPARNFVELVGQLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHA0</accession>
    <name>A0A0S2DHA0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA-binding response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Photosynthetic apparatus regulatory protein RegA</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">regA</name>
        <name evidence="4" type="ORF">BV903_02150</name>
        <name evidence="5" type="ORF">FE772_11870</name>
        <name evidence="3" type="ORF">GLE_2371</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000004">
        <property type="protein sequence ID" value="OPD65588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947488.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2371"/>
    <dbReference type="EnsemblBacteria" id="ALN57720">
        <property type="protein sequence ID" value="ALN57720"/>
        <property type="gene ID" value="GLE_2371"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65588">
        <property type="protein sequence ID" value="OPD65588"/>
        <property type="gene ID" value="BV903_02150"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2371"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2332"/>
    <dbReference type="OMA" id="KTLEWEH"/>
    <dbReference type="OrthoDB" id="930905at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="21"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD65588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="193" mass="21309" checksum="D09DA419EB7D187D" modified="2016-02-17" version="1">MSEELPPLPPGFDDEDDEPRRLLIVEDDAAFARTLTRSFERRGYLVHNASNLAEVQALLGEHTPGYAVVDLKLAGGDSGLACVQALHAHDEDMLIVVLTGYASIATAVEAIKLGALHYLAKPSNTDDIEAAFGRAQGDVNVELTERQTSIKTLEWERIHEMLAATDFNISETARRLGMHRRTLARKLGKHRIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHK8</accession>
    <name>A0A0S2DHK8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Penicillinase repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2759</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BlaI transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2759"/>
    <dbReference type="EnsemblBacteria" id="ALN58107">
        <property type="protein sequence ID" value="ALN58107"/>
        <property type="gene ID" value="GLE_2759"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2759"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="112" mass="12646" checksum="07ED5DB6160981E6" modified="2016-02-17" version="1">MLWDRGEASVREVADALSQHKPVAYTTVLTTFNVLAKKGFVTHRQEGRAFVYRAAISREQARRQALDQLLLRFFEGSPNLLAQHLLDQDEVGRDELKALRAKVEAAKQRGNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHL1</accession>
    <name>A0A0S2DHL1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclic beta 1-2 glucan synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_12635</name>
        <name evidence="2" type="ORF">GLE_2515</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="RefSeq" id="WP_057947599.1">
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_2515"/>
    <dbReference type="EnsemblBacteria" id="ALN57864">
        <property type="protein sequence ID" value="ALN57864"/>
        <property type="gene ID" value="GLE_2515"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2515"/>
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    <dbReference type="OrthoDB" id="16639at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="526"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="550"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="647"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="673"/>
            <end position="693"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="710" mass="78792" checksum="F5E50895ADCF4B4D" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHM1</accession>
    <name>A0A0S2DHM1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Type IV secretion system protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">virB11</name>
        <name evidence="5" type="ORF">BV903_06245</name>
        <name evidence="7" type="ORF">D9T17_16155</name>
        <name evidence="6" type="ORF">FE772_14080</name>
        <name evidence="4" type="ORF">GLE_2819</name>
    </gene>
    <organism evidence="4 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 8">C3</strain>
        </source>
    </reference>
    <reference evidence="5 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">OH11</strain>
        </source>
    </reference>
    <reference evidence="6 11" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Part of the Type IV secretion system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000011">
        <property type="protein sequence ID" value="OPD64804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000040">
        <property type="protein sequence ID" value="ROU05954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947838.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2819"/>
    <dbReference type="EnsemblBacteria" id="ALN58167">
        <property type="protein sequence ID" value="ALN58167"/>
        <property type="gene ID" value="GLE_2819"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64804">
        <property type="protein sequence ID" value="OPD64804"/>
        <property type="gene ID" value="BV903_06245"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2819"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2776"/>
    <dbReference type="OMA" id="HDERVIT"/>
    <dbReference type="OrthoDB" id="473670at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043684">
        <property type="term" value="C:type IV secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044097">
        <property type="term" value="P:secretion by the type IV secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014155">
        <property type="entry name" value="VirB11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02788">
        <property type="entry name" value="VirB11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="3">
        <location>
            <begin position="27"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU366071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD64804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW26620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROU05954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="346" mass="38473" checksum="3D3B2F8BEAAE7C07" modified="2016-02-17" version="1">MDSDNSPIAQVSNDFLDYQYQVLGILEYMSSPDVTEICINRPGELYLETRAGWQRLEVPSLTFDRARQFCTAVVNESNTGQRITDADPVVSLTFPTGQRAQFVIPPACDAGKVSITIRLPSKHNKTLQQYQDDGFFQQILESTASVSDQDRELLEIRGQRNYAEFFKKAVQYKKNIVVAGATGSGKTTFMKSLVGHIPDYERLVTIEDARELFITQPNVVHLLYSKGGQSTSNVTAKSCMEACLRMKPDRIILAELRGDESFYFIRNCASGHPGSITSCHAGSTAQTWDQLALMVKASNEGSGLEFAVIKRLLMLTIDIVVHIKAHAGQRHITGIDFNPERQLAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHR5</accession>
    <name>A0A0S2DHR5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Aldehyde dehydrogenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Aldehyde dehydrogenase (NAD) family protein</fullName>
            <ecNumber evidence="6">1.2.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FE772_13385</name>
        <name evidence="6" type="ORF">GLE_2672</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.-" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947722.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2672"/>
    <dbReference type="EnsemblBacteria" id="ALN58020">
        <property type="protein sequence ID" value="ALN58020"/>
        <property type="gene ID" value="GLE_2672"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2672"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2631"/>
    <dbReference type="OMA" id="ANVEHEM"/>
    <dbReference type="OrthoDB" id="744602at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="5">
        <location>
            <begin position="17"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW26506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="475" mass="50229" checksum="24905E16FC657515" modified="2016-02-17" version="1">MQTFRHWIDGTPRDAADGRWLEVFDPANAQPYAQVAAGGAAEVEAAVAAAQAAFPAWSGLAHSERAQWLERLAAALEARTGEFAAAESRDGGKPIRLAREAEIPRAVSNLRFYAHAATQFASESHHGQAGLNYTLRQPLGPVAAISPWNLPLYLFTWKIAPALAAGNTVVAKPSEVTPATATMLGELCAQIGLPAGVLNIVHGLGPEVGAPLVAHPAVRAVSFTGSTAVGRGIAATCAPLLRKVSLELGGKNPTLIFADSDWREHLDLLVRSAFQNSGQICLCGSRILVERSIYAEVREALVERAQALRVGEPGEETTALGPLVSQAHFAKVVAALERARAEGGRVLCGGAALERPGWYVAPTLLEGLGPDTASNREEIFGPVATLQPFDDDTHALALANASDYGLSASLWTRDLARAHRLAARLNVGMVWINTWLQRDLRTPFGGAGASGLGREGGVEALRFFTEAKNVGLHLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHZ0</accession>
    <name>A0A0S2DHZ0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cupin superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2719</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947764.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2719"/>
    <dbReference type="EnsemblBacteria" id="ALN58067">
        <property type="protein sequence ID" value="ALN58067"/>
        <property type="gene ID" value="GLE_2719"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2719"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2678"/>
    <dbReference type="OMA" id="VDQFVPE"/>
    <dbReference type="OrthoDB" id="1885303at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039994">
        <property type="entry name" value="JmjC_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13096">
        <property type="entry name" value="PTHR13096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08007">
        <property type="entry name" value="Cupin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="2">
        <location>
            <begin position="112"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="418" mass="45773" checksum="655C6EE829F2954C" modified="2016-02-17" version="1">MAKKTAPAFPIEIDAARRPPLGMSPAAFLRDYWQKRPLLIRNAFPGLQSPLQPEDLAGLACEEGALARLIQHDRARDHYSVRHGPFEESDFPGLPRQDWTLLVQDVDKWDADVAALLPAFAFLPRWRIDDVMISFAAPGGSVGAHVDQYDVFLLQGQGHRRWQIDARPNPPQDFRNDAELKLLREFEPSHEWLLGPGDMLYLPPGVPHHGVAEDACLTFSIGMRAPSSAELMGDYIDTLAADADEALRYADPDLAPPRDPNEIDAAAMQRAVQALNALRMNDPDRLGDWFGRFITVYRAAGEVSAGGAPAPARAELEFALDQGATLWRHPWSRMAWRRAHAKGGAARLYVSGQEFALPAKDAQALAAAAELDLAGYSALSAAGRDCVLALVAGGHYRLGRDDQDDADGYDGEDGGEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHZ3</accession>
    <name>A0A0S2DHZ3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytochrome c-type biogenesis protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ccmH</name>
        <name evidence="7" type="ORF">GLE_2833</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Possible subunit of a heme lyase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the CcmH/CycL/Ccl2/NrfF family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2833"/>
    <dbReference type="EnsemblBacteria" id="ALN58181">
        <property type="protein sequence ID" value="ALN58181"/>
        <property type="gene ID" value="GLE_2833"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2833"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2791"/>
    <dbReference type="OMA" id="MIAADMR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005616">
        <property type="entry name" value="CcmH/CycL/Ccl2/NrfF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038297">
        <property type="entry name" value="CcmH/CycL/NrfF/Ccl2_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03918">
        <property type="entry name" value="CcmH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011020826" description="Cytochrome c-type biogenesis protein" evidence="5">
        <location>
            <begin position="37"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="183" mass="19709" checksum="7E7679F3827788B5" modified="2016-02-17" version="1">MSAAGPRAAAPGGARRIAATLRHAACAALLSASACAMLSAPLSAQPANDPAPLRYSDPAEERRFHDLVAELRCVMCQNQSLADSNAQIAHDLRREVLDLMRQGKSDAQIKEFLVARYGEFVLYRPRVESTTWLLWFGPALVLLAGGYLVARVIRTRASGTGADDGTATDLGRTSRGGEDEQEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHZ5</accession>
    <name>A0A0S2DHZ5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2768</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947798.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2768"/>
    <dbReference type="EnsemblBacteria" id="ALN58116">
        <property type="protein sequence ID" value="ALN58116"/>
        <property type="gene ID" value="GLE_2768"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2768"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2725"/>
    <dbReference type="OMA" id="IAQHCIL"/>
    <dbReference type="OrthoDB" id="1928091at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="13"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="350" mass="36874" checksum="0DCA437CD79A389B" modified="2016-02-17" version="1">MNASASSIAPATILITGGSGFLGSRCIAQALAAGHRVRASVRDPAREPQLRAALARAGVDAGDRLSLHAADLRRDDGWSAAAAGCDYALHVASPFPAEIPRDENELIAPAREGTLRVLRAARDAGLRRVVLTSSFAAVGYGHPPRPAPFDESVWSDTAAPLAPYVKSKTLAERAAWEFVAGEGGGLELAVVNPVGIFGPVLSDDYATSILLVKRLLDGALPGTPKLHFGVVDVRDVAELHLRVMTDPAARGERFLATAGDFLSVSEMAALLRRNLGAAARKAPTRELPNWLVRLAALADPAVRQIVPDLGNRKNASNAKAKRVLGWNPRSAEEALVATARSLIELGVVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI52</accession>
    <name>A0A0S2DI52_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Coproporphyrinogen III oxidase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_2870</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2870"/>
    <dbReference type="EnsemblBacteria" id="ALN58218">
        <property type="protein sequence ID" value="ALN58218"/>
        <property type="gene ID" value="GLE_2870"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2870"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2832"/>
    <dbReference type="OMA" id="SMRMFRA"/>
    <dbReference type="OrthoDB" id="1130951at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034505">
        <property type="entry name" value="Coproporphyrinogen-III_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932">
        <property type="entry name" value="PTHR13932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="6">
        <location>
            <begin position="50"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="466" mass="52169" checksum="4875936572CF57EA" modified="2016-02-17" version="1">MNAVVNPIPAPSLAELLRLPPYQAYSYSYPHKTAYRPLQPPRGLRELWAGEPRDSLFLYLHVPFCSYRCGFCNLFALARPELAKVERYLEQMERQLRTTCEALDEHRFVRFAIGGGTPSYLDAAQLRRLFDMVERHATIDLRAIPAGIEVSPETVDEDKMRLCRERGIDRVSMGIQSFSEAEVRALVRPQQRAVVEQAIAAIRAAGVPTLNLDLIYGIAGQTVASFLASIDSALEHCPEELYLYPLYVRPLTGLGRIEAKAEAKFEAKAGARLPLQAEPMDERLALYQAGRDRLLAAGYQQVSMRMFRAPHAPDVAAPVYCCQSDGMVGIGCGARSYTSTLHYSSEYGVARRSVAEILDHYLERDPASFAAADYGIALGEEERRRRHAIQSLLIRPGLDRADYRRRFGADCLDHLPQLRELFAHALAVENGEWIELTDAGLARADTIGPWLASAAIVERMRDYRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI76</accession>
    <name>A0A0S2DI76_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_14190</name>
        <name evidence="2" type="ORF">GLE_2842</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947853.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58190">
        <property type="protein sequence ID" value="ALN58190"/>
        <property type="gene ID" value="GLE_2842"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2842"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2800"/>
    <dbReference type="OrthoDB" id="1968059at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242317" evidence="1">
        <location>
            <begin position="19"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="152" mass="16772" checksum="7A23990F5D7714A9" modified="2016-02-17" version="1">MKYALAFAAVLFVAPACATSIVPKPLEELVRESDHVVVATVVGVDMVDGRGRALNDPAARTGPGSANRMSFELKVESVLFTRAGSLPPRIRVPLWSMWHYQLGTMRDEVVGSRGIFLLKGAPPKGDRYEPAYPGGFQRPLEEREQIERLLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI91</accession>
    <name>A0A0S2DI91_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Heme exporter protein D</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ccmD</name>
        <name evidence="13" type="ORF">BV903_06295</name>
        <name evidence="14" type="ORF">FE772_14130</name>
        <name evidence="12" type="ORF">GLE_2829</name>
    </gene>
    <organism evidence="12 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">C3</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">B25</strain>
        </source>
    </reference>
    <reference evidence="14 17" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 11">Cell inner membrane</location>
            <topology evidence="3 11">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the CcmD/CycX/HelD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000011">
        <property type="protein sequence ID" value="OPD64813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58177">
        <property type="protein sequence ID" value="ALN58177"/>
        <property type="gene ID" value="GLE_2829"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64813">
        <property type="protein sequence ID" value="OPD64813"/>
        <property type="gene ID" value="BV903_06295"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2829"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2787"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015886">
        <property type="term" value="P:heme transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007078">
        <property type="entry name" value="Haem_export_protD_CcmD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04995">
        <property type="entry name" value="CcmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03141">
        <property type="entry name" value="cytochro_ccmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN58177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OPD64813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW26628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="58" mass="6459" checksum="A51A8529AA917278" modified="2016-02-17" version="1">MTHLPYIVGAYAVFAVVLGWDYVSSALQIRRELRIARQRAARAAARPASRDASTELSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIE7</accession>
    <name>A0A0S2DIE7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF4159 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_13365</name>
        <name evidence="3" type="ORF">GLE_2667</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947718.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2667"/>
    <dbReference type="EnsemblBacteria" id="ALN58015">
        <property type="protein sequence ID" value="ALN58015"/>
        <property type="gene ID" value="GLE_2667"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2667"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2626"/>
    <dbReference type="OMA" id="PKIHEHD"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025297">
        <property type="entry name" value="DUF4159"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13709">
        <property type="entry name" value="DUF4159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242309" evidence="1">
        <location>
            <begin position="20"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4159" evidence="2">
        <location>
            <begin position="35"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="233" mass="26677" checksum="9895BD4FB3703423" modified="2016-02-17" version="1">MNRARFLRLMLGAAVGAVAARVPLARAAADYDFWFTRLKYDSGDWDVDQRMPANLITSLIDYTHLRVDPKEHVLALADPKMLAAPFCYLAGHKLVEFNPDERRNFERYVRNGGFVFVDDCNHDIDGLFAKSFEAQMAKIFGAKALKKLPNKHPVYRSFFVFDGPPATGFELNGWGDDLVHDYLKGIEIDGRLGILYSNKDYGCEWDYDWRNKRFLAEDNTKFGVNIVMYALNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIK6</accession>
    <name>A0A0S2DIK6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0178 protein BV903_21985</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_21985</name>
        <name evidence="5" type="ORF">FE772_15560</name>
        <name evidence="3" type="ORF">GLE_3128</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0178 family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN58475">
        <property type="protein sequence ID" value="ALN58475"/>
        <property type="gene ID" value="GLE_3128"/>
    </dbReference>
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        <property type="gene ID" value="BV903_21985"/>
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    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
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    </dbReference>
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        <property type="match status" value="1"/>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD61719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="160" mass="17404" checksum="B8347CBA353DF7E3" modified="2016-02-17" version="1">MTDTSAAPPAAPQIWVDADACPVVIKDILFRAAERAQIPLTLVANQWLRTPPSRWIRAIQVPSGADVADTEIVQRLAAGDLVVTQDIPLASLALAKGAVALNPRGDLYTRDNIAERLSIRNFMEELRGAGVQTGGPPALHARDRQAFAAQLDRWLARRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIU6</accession>
    <name>A0A0S2DIU6_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">GLE_3069</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58416">
        <property type="protein sequence ID" value="ALN58416"/>
        <property type="gene ID" value="GLE_3069"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3069"/>
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    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="122" mass="12902" checksum="799C71D85229787E" modified="2016-02-17" version="1">MSYQPPKSPTSAPAQSPFNPAWLLAGLVASSIAGVGSLLLVPQFSQVWASFDAELPALTACLQAYPWAPCLLPVAVLMVWAAAPRARRDRWACAFGVFAGMAAIALMLVALYLPIFVLASKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIZ7</accession>
    <name>A0A0S2DIZ7_LYSEN</name>
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            <fullName evidence="4">Amidohydrolase</fullName>
        </submittedName>
        <submittedName>
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            <ecNumber evidence="3">3.8.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">atzA</name>
        <name evidence="4" type="ORF">FE772_15395</name>
        <name evidence="3" type="ORF">GLE_3087</name>
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    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
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            <taxon>Gammaproteobacteria</taxon>
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    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.8.1.8" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948031.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3087"/>
    <dbReference type="EnsemblBacteria" id="ALN58434">
        <property type="protein sequence ID" value="ALN58434"/>
        <property type="gene ID" value="GLE_3087"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3087"/>
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    <dbReference type="OMA" id="LYNSMNG"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:atrazine chlorohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <location>
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        </location>
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            <end position="690"/>
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        <location>
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            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="690" mass="74595" checksum="C978D5F9C12D2B51" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ67</accession>
    <name>A0A0S2DJ67_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="1 2">
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        <lineage>
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            <taxon>Lysobacter</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58303">
        <property type="protein sequence ID" value="ALN58303"/>
        <property type="gene ID" value="GLE_2955"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2955"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2917"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="41" mass="4680" checksum="DFC37B040CFF90E2" modified="2016-02-17" version="1">MGRAPVKLGGHDNHHFGTRAFVARLRRRGPCEARAERRRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ78</accession>
    <name>A0A0S2DJ78_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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        </lineage>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58319">
        <property type="protein sequence ID" value="ALN58319"/>
        <property type="gene ID" value="GLE_2971"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2971"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2932"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="91" mass="9827" checksum="BA2584BD372733F2" modified="2016-02-17" version="1">MKITVRACRMASVSNPPRPVVPAKAGIHFDFASPGNRHTAKATTKWIPAFAGMTGTRQVSAAISSRLARREHPPSPTSTCIIATHRPQDRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJB2</accession>
    <name>A0A0S2DJB2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Multidrug resistance protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_3266</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3266"/>
    <dbReference type="EnsemblBacteria" id="ALN58612">
        <property type="protein sequence ID" value="ALN58612"/>
        <property type="gene ID" value="GLE_3266"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3266"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3219"/>
    <dbReference type="OMA" id="FRRRGMY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="290"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="466"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="4"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="502" mass="54029" checksum="CC84022943079A91" modified="2016-02-17" version="1">MALTTLGLALASFMQVLDTTIANVSLPTISGNLGGSANQATWVITSFAVSNAIALPLTGFFTRKFGERKLFMWATLLFVIASFLCGLANSMGLLVAARALQGFVAGPMYPVTQALLISIYPPHKRGQAIALLAMVTVVAPIAGPILGGWITDNYSWEWIFFINVPIGIFASIVVGNQLRGRPERLDNPKMDYMGLAMLVIGVAALQIMLDLGNDEDWFNSTTIVALTIVAVIALAVFVIWELTERDPIVNLRLFRHRNFASGTAAMVLAYSAFFAIGLLVPLWLQRNLGYTSIWAGLATAPIGILPVLLTPFVGLYAARFDLRWVATGAFIVMAATSFVRSGFNLDVDFQHVALVQLWQGLGVALFFMPVLTILLSDLEPHEIAAGSGLATFVRTLGGSFAASLTTWAWNQRSTIHHAQLTEHIGAYDPQIQQTVDQLGRGDPTRGALALNQMISQQAAQIGFNEMLYLIGILFVVVTAFVWMAKPPFSAKVGGGAAAAGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJC0</accession>
    <name>A0A0S2DJC0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3029</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58376">
        <property type="protein sequence ID" value="ALN58376"/>
        <property type="gene ID" value="GLE_3029"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3029"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2989"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="97" mass="9888" checksum="52D976BF8B4C528A" modified="2016-02-17" version="1">MRCFGGCGFSGRDLGGCDLGGYGLRRRGRVGHGPGVRVGQVGAHARALRETAPARARKLTAAAARRDEGTKTMAGVAGKSIGGGWRPASRPADRGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJE1</accession>
    <name>A0A0S2DJE1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">TonB family C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLE_3411</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TonB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948275.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3411"/>
    <dbReference type="EnsemblBacteria" id="ALN58757">
        <property type="protein sequence ID" value="ALN58757"/>
        <property type="gene ID" value="GLE_3411"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3411"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3361"/>
    <dbReference type="OMA" id="SHHAHES"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_C" evidence="10">
        <location>
            <begin position="146"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN58757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="227" mass="24814" checksum="406932F40E6AB2EF" modified="2016-02-17" version="1">MVRTLPSHHAHESLDGTRIAANAGAIAFNAAMLMLMLAPLSAPQLITQQMEQLPEFHLIDRKKVLPPPPPPPKKEEVIRKVVKDPPPQIQRPVQQQVAPPQEVVVDQPALPMDFQGVEQVAIATPPSTNVGRGIIEGATLQVLRNPAPTYPVDAIRNNLTGTVELEILVGIDGKPLDVSIVRSSGHRSLDQAARKVVLQRWTFQPAMENGQAVQARGRVPIQFKLDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJQ4</accession>
    <name>A0A0S2DJQ4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTPase Obg</fullName>
            <ecNumber evidence="5">3.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP-binding protein Obg</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">obgE</name>
        <name evidence="5" type="synonym">obg</name>
        <name evidence="9" type="ORF">BV903_20970</name>
        <name evidence="10" type="ORF">FE772_16290</name>
        <name evidence="8" type="ORF">GLE_3291</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000066">
        <property type="protein sequence ID" value="OPD61954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948183.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000066.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3291"/>
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        <property type="protein sequence ID" value="ALN58637"/>
        <property type="gene ID" value="GLE_3291"/>
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        <property type="gene ID" value="BV903_20970"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="P-loop_NTPase"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="MMR_HSR1"/>
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    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002401">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82051">
        <property type="entry name" value="SSF82051"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02729">
        <property type="entry name" value="Obg_CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00905">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51883">
        <property type="entry name" value="OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Obg" evidence="7">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="OBG-type G" evidence="6">
        <location>
            <begin position="160"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="166"/>
            <end position="173"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="191"/>
            <end position="195"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="213"/>
            <end position="216"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="287"/>
            <end position="290"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="318"/>
            <end position="320"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00007699"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
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    </evidence>
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            <dbReference type="HAMAP-Rule" id="MF_01454"/>
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    </evidence>
    <evidence type="ECO:0000259" key="6">
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            <dbReference type="PROSITE" id="PS51710"/>
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    </evidence>
    <evidence type="ECO:0000259" key="7">
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            <dbReference type="PROSITE" id="PS51883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD61954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW26962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="355" mass="38185" checksum="528BEA47542F1D6A" modified="2016-02-17" version="1">MKLVDEAEIQVIAGNGGNGCVGFRREKFIPLGGPDGGDGGDGGSVYLLADENLNTLVDFRHQKQFRAKRGENGMGRQMYGKGGEDLIIVVPVGTVVTNVETDEVIGDLTAHGDRLLVARGGKGGLGNMHFKSSINRTPRKALPGLPGEERMLKMELKLLADVGLLGFPNAGKSTLIRAVSAATPKVADYPFTTLYPNLGVVSVEAHRSFVIADIPGLIEGAADGAGLGAQFLRHLQRTRLLLHLVDIAPMEGGVEGLSPAEQVRAIENELRKHDPELLDKPRWLVFNKSDLLLDEERDGIVRATLAELGWTDRWYVVSAIGREGTAPIMRDVMAFFDRQREDALEAASAAGGHAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJY2</accession>
    <name>A0A0S2DJY2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)</fullName>
            <ecNumber evidence="3">2.5.1.31</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Ditrans,polycis-undecaprenylcistransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Undecaprenyl diphosphate synthase</fullName>
            <shortName evidence="3">UDS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Undecaprenyl pyrophosphate synthase</fullName>
            <shortName evidence="3">UPP synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 4" type="primary">uppS</name>
        <name evidence="5" type="ORF">BV903_17730</name>
        <name evidence="6" type="ORF">D9T17_11455</name>
        <name evidence="4" type="ORF">GLE_3375</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">C3</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">OH11</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(2E,6E)-farnesyl diphosphate + 8 isopentenyl diphosphate = di-trans,octa-cis-undecaprenyl diphosphate + 8 diphosphate</text>
            <dbReference type="Rhea" id="RHEA:27551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="3">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.31" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000048">
        <property type="protein sequence ID" value="OPD62516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000025">
        <property type="protein sequence ID" value="ROU06902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948249.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3375"/>
    <dbReference type="EnsemblBacteria" id="ALN58721">
        <property type="protein sequence ID" value="ALN58721"/>
        <property type="gene ID" value="GLE_3375"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62516">
        <property type="protein sequence ID" value="OPD62516"/>
        <property type="gene ID" value="BV903_17730"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3375"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3325"/>
    <dbReference type="OMA" id="PRTEGHK"/>
    <dbReference type="OrthoDB" id="1630604at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008834">
        <property type="term" value="F:di-trans,poly-cis-decaprenylcistransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01139">
        <property type="entry name" value="ISPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018520">
        <property type="entry name" value="UPP_synth-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="PTHR10291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="SSF64005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01066">
        <property type="entry name" value="UPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="3" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="23"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="67"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="196"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="22"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD62516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROU06902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <sequence length="255" mass="28693" checksum="C5643E4EB3000C28" modified="2016-02-17" version="1">MPSEPANAAPARIPRHLAVIMDGNGRWAERRRRPRIIGHRAGARAVNVCIDFCIERGVQALTLFAFSSENWGRPEDEVGGLMKLFLNALEREVEELDRRGVRVRFIGERERFSDKIRERMAAAERQTERNGALHLTIAASYGGRWDIAQAARSLAQDVAAGRLAPQDIDERLLGARVCLADLPPPDLFIRTGGDTRISNFLLWQLAYTELWFTEALWPELDAAMLQRALDEYAGRERRFGLTGAQIAAQTNETVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK36</accession>
    <name>A0A0S2DK36_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3387</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58733">
        <property type="protein sequence ID" value="ALN58733"/>
        <property type="gene ID" value="GLE_3387"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3387"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3337"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="68" mass="7388" checksum="1BBF57E9E81C8520" modified="2016-02-17" version="1">MAGRALRSRDPEHRLGRASXXXXXXXPTVESPGPATARPTARRTIPNPVRSAARRRSRRVKPCPTAPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKD6</accession>
    <name>A0A0S2DKD6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Taurine catabolism dioxygenase TauD/TfdA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3674</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3674"/>
    <dbReference type="EnsemblBacteria" id="ALN59018">
        <property type="protein sequence ID" value="ALN59018"/>
        <property type="gene ID" value="GLE_3674"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3674"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3616"/>
    <dbReference type="OMA" id="DEFIYYH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD" evidence="2">
        <location>
            <begin position="26"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="323" mass="35781" checksum="B2E00F4E5279D496" modified="2016-02-17" version="1">MDMNRKRLDGDVPAPLLVTPAHAHCDLAALLAERASEIKDDLLEHGALLFRGFAVDSVEKFGAVADQIGNARLNYTYRSTPRTSLGGGVFTATEFPQSQEIPLHCENAYQRDWPMLVAFCCLTPADVGGATPIASMREATQAIGAALMDEFEHRQVKYVRHYRPYVDLPWETVFQTDDKAEVARFCDSAGIEHEWLDEETLRTGQVCQGVANHPVTGEKLFFNQAHLFHVSSLGEETAQSMIDMFGADQLPRQSFFGDGSDIPADVLQAVRDGLNRKAYDVAWQRGDVLLLDNMQFAHGRRTFSGPRKIAVTLSNPYSGHLPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKI7</accession>
    <name>A0A0S2DKI7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Trehalose 6-phosphate phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">otsB</name>
        <name evidence="5" type="ORF">FE772_18270</name>
        <name evidence="4" type="ORF">GLE_3708</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Removes the phosphate from trehalose 6-phosphate to produce free trehalose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>alpha,alpha-trehalose 6-phosphate + H2O = alpha,alpha-trehalose + phosphate</text>
            <dbReference type="Rhea" id="RHEA:23420"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58429"/>
            <dbReference type="EC" id="3.1.3.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 3">Glycan biosynthesis; trehalose biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the trehalose phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.12" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948490.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3708"/>
    <dbReference type="EnsemblBacteria" id="ALN59052">
        <property type="protein sequence ID" value="ALN59052"/>
        <property type="gene ID" value="GLE_3708"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3708"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3653"/>
    <dbReference type="OMA" id="YGAERWD"/>
    <dbReference type="OrthoDB" id="1374424at2"/>
    <dbReference type="UniPathway" id="UPA00299"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004805">
        <property type="term" value="F:trehalose-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044651">
        <property type="entry name" value="OTSB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003337">
        <property type="entry name" value="Trehalose_PPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43768">
        <property type="entry name" value="PTHR43768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02358">
        <property type="entry name" value="Trehalose_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00685">
        <property type="entry name" value="T6PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW27293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="251" mass="26322" checksum="7B9A80CE6B67C1C9" modified="2016-02-17" version="1">MASIRTLRTAPPAPAPDWALFLDVDGCLLEHAPAPHLARVPAQLPQRLLRLAAELDGALALVSGRSLQSLQALFPDCADLCLSGMHGLERRSAHAPLRAPAPPESMLALAGEAARFALDYPGACIEAHGPCLNLHWRAAPQAAAAMGEFADAALTRLPGYRQHRGAHGIEIRPDGMDKGRAIAELLGLAPFRGRVPVFAGDDPADEPGFAMVNAHGGISVLVGERDDTGARHRLAAPAQVRAWLGVSAEAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKK2</accession>
    <name>A0A0S2DKK2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3836</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59179">
        <property type="protein sequence ID" value="ALN59179"/>
        <property type="gene ID" value="GLE_3836"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3836"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3778"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="90" mass="9511" checksum="FF8E336FA6FD0B34" modified="2016-02-17" version="1">MQRAESDASQLNRYRVRASAVLACVPHAKKKTPAGAGARTSSPSWEASPRDACARRRGAASYGPASAGAKHTGSRQAGPQPPVRRRTVRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKN7</accession>
    <name>A0A0S2DKN7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3748</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948520.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59092">
        <property type="protein sequence ID" value="ALN59092"/>
        <property type="gene ID" value="GLE_3748"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3748"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3692"/>
    <dbReference type="OMA" id="NDGDIEW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595364" evidence="1">
        <location>
            <begin position="28"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="250" mass="26116" checksum="A6CF5208A01A04E3" modified="2016-02-17" version="1">MKPFASKLAGAVVALAIACAPLSAAHAQNRTATDAQGQALKVEGSVVLIEPDIELSLVSAGGLAEPRKEWSEAARKLYPQAVRELLAGSKAERRDDYDVPDDLDPNSQMGQIVRLNQAVALSISQYSLGGALATKKDAKTGKPRMDWSLGPGVAGLREATGADYALFTYIRDSYATGGRTAVRVLTMLAGAALGTYIDVGGGSQVGVATLVDLRTGQVVWFNQMVKGSGDLRDEKGAKGTVASMLKGIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKQ9</accession>
    <name>A0A0S2DKQ9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6 7">50S ribosomal protein L10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">rplJ</name>
        <name evidence="9" type="ORF">BV903_21085</name>
        <name evidence="10" type="ORF">FE772_18695</name>
        <name evidence="8" type="ORF">GLE_3799</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000067">
        <property type="protein sequence ID" value="OPD61936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948563.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000067.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3799"/>
    <dbReference type="EnsemblBacteria" id="ALN59143">
        <property type="protein sequence ID" value="ALN59143"/>
        <property type="gene ID" value="GLE_3799"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61936">
        <property type="protein sequence ID" value="OPD61936"/>
        <property type="gene ID" value="BV903_21085"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3799"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3743"/>
    <dbReference type="OMA" id="VRDQKQA"/>
    <dbReference type="OrthoDB" id="1470978at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05797">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00362">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022973">
        <property type="entry name" value="Ribosomal_L10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_L10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002363">
        <property type="entry name" value="Ribosomal_L10_eubac_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_L10P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11560">
        <property type="entry name" value="PTHR11560"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="SSF160369"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01109">
        <property type="entry name" value="RIBOSOMAL_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD61936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="177" mass="18414" checksum="63C6D11E73379C2C" modified="2016-02-17" version="1">MALNLSQKQEVVAELAEVAAKAHSLIAAEYAGITVGQLTAMRKKARETGVYLRVVKNTLASRAVAGTEFECVQDKLVGPLLYAFSVDEPGAAGRLIKEFAKGNDKLKAQVVAVGGQVYPASHVEVLASLPTLDQALSMLARVLSEPAAMFARAVKAVADQQGGGEVAAEAPAEAEPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKV5</accession>
    <name>A0A0S2DKV5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">PKD domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Zinc carboxypeptidase/PKD domain/proprotein convertase P-domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FE772_18895</name>
        <name evidence="6" type="ORF">GLE_3839</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948591.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3839"/>
    <dbReference type="EnsemblBacteria" id="ALN59182">
        <property type="protein sequence ID" value="ALN59182"/>
        <property type="gene ID" value="GLE_3839"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3839"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3780"/>
    <dbReference type="OMA" id="SIPGYAC"/>
    <dbReference type="OrthoDB" id="141368at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002884">
        <property type="entry name" value="P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01483">
        <property type="entry name" value="P_proprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51829">
        <property type="entry name" value="P_HOMO_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242683" evidence="3">
        <location>
            <begin position="21"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="4">
        <location>
            <begin position="564"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="domain" description="P/Homo B" evidence="5">
        <location>
            <begin position="647"/>
            <end position="761"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW27400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="761" mass="80040" checksum="EB708165BC04CCFE" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL04</accession>
    <name>A0A0S2DL04_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_18000</name>
        <name evidence="2" type="ORF">GLE_3661</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948451.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59005">
        <property type="protein sequence ID" value="ALN59005"/>
        <property type="gene ID" value="GLE_3661"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3661"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3605"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726578" evidence="1">
        <location>
            <begin position="29"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="106" mass="11073" checksum="A337649CDF246370" modified="2016-02-17" version="1">MKKSLTTVLPASLATVLLGLALAGAAVAAPPGGIGTQPQPPQPFGTWQAKVKYLSPHTAPDGRRLTWKYADIVASTQEYCDAQLQSWMSGGNASVVEYCHFVTAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL23</accession>
    <name>A0A0S2DL23_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3818</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948574.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3818"/>
    <dbReference type="EnsemblBacteria" id="ALN59161">
        <property type="protein sequence ID" value="ALN59161"/>
        <property type="gene ID" value="GLE_3818"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3818"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3760"/>
    <dbReference type="OMA" id="ELEDERW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="SSF48613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="195" mass="21831" checksum="5789C3C73DEB3E3E" modified="2016-02-17" version="1">MRRLAVFSPFAGPSLDTLHQQLRSATAAQHRDLDAMLADSLDDRRGYLRYLLGMLSLVELLAPPPAAVDARSAWTEWFDPQRRALLHQDLRELGLLPLAYRPAALPASCWMGANYVLEGSALGARVLLRAAERLRLRDPRVPLAFLRHHARPGDRWPRFLDELQTLDGDLRDDAARGARHAFALVADALIEKESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL47</accession>
    <name>A0A0S2DL47_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histone deacetylase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3908</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histone deacetylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3908"/>
    <dbReference type="EnsemblBacteria" id="ALN59250">
        <property type="protein sequence ID" value="ALN59250"/>
        <property type="gene ID" value="GLE_3908"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3908"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3845"/>
    <dbReference type="OMA" id="GRAMGFC"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="His_deacetylse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hist_deacetyl" evidence="2">
        <location>
            <begin position="3"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="279" mass="29628" checksum="ED713C88EA3B0F14" modified="2016-02-17" version="1">MAVTESLREAFAERLHWCEAPAASRGQLLRAHSDELLALVLDTPVDGPVQLDPDTVLAPGSAEAALRAAGAGVAAVDSVLKGEDRRAFCAVRPPGHHATVHAAMGFCLFNNIAVAAAHACDKHGLARVAVIDFDVHHGNGTQAIFDSDPRVLYVSSHQLPLYPDTGYAHERGIGNIVNAPLPAGTGSDGFRRVWRERLLPIVDGFRPQLVLISAGFDAHKRDPLAQIELDGEDFAWLTAELVAIAERHAAGRVVSMLEGGYDLAALRESAVAHVGAMLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL72</accession>
    <name>A0A0S2DL72_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Large Ala/Gln-rich protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4040"/>
    <dbReference type="EnsemblBacteria" id="ALN59382">
        <property type="protein sequence ID" value="ALN59382"/>
        <property type="gene ID" value="GLE_4040"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4040"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3982"/>
    <dbReference type="OMA" id="QHNIANS"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018712">
        <property type="entry name" value="DUF2235"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09994">
        <property type="entry name" value="DUF2235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2235" evidence="2">
        <location>
            <begin position="122"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="648"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="924"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="931"/>
            <end position="945"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="959" mass="104117" checksum="792AC942FD6719B7" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLC4</accession>
    <name>A0A0S2DLC4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3954</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59296">
        <property type="protein sequence ID" value="ALN59296"/>
        <property type="gene ID" value="GLE_3954"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3954"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3891"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="40" mass="4731" checksum="FB220CC88EF9AF17" modified="2016-02-17" version="1">MRWRIEARPFFARSTARRSMQIRRDAAAVPMAPRMPYAHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLE4</accession>
    <name>A0A0S2DLE4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">pilL</name>
        <name evidence="11" type="ORF">GLE_3958</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948675.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3958"/>
    <dbReference type="EnsemblBacteria" id="ALN59300">
        <property type="protein sequence ID" value="ALN59300"/>
        <property type="gene ID" value="GLE_3958"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3958"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3895"/>
    <dbReference type="OMA" id="EMDRHSQ"/>
    <dbReference type="OrthoDB" id="305000at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004105">
        <property type="entry name" value="CheA-like_dim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02895">
        <property type="entry name" value="H-kinase_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
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    <feature type="domain" description="HPt" evidence="10">
        <location>
            <begin position="699"/>
            <end position="806"/>
        </location>
    </feature>
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        <location>
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            <end position="1548"/>
        </location>
    </feature>
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        <location>
            <begin position="1693"/>
            <end position="1945"/>
        </location>
    </feature>
    <feature type="domain" description="CheW-like" evidence="9">
        <location>
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            <end position="2080"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
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            <end position="2219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
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            <end position="607"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
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    <feature type="region of interest" description="Disordered" evidence="6">
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        <location>
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        </location>
    </feature>
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        <location>
            <position position="1491"/>
        </location>
    </feature>
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        <location>
            <position position="2152"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
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        <source>
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        <source>
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        <source>
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            <dbReference type="PROSITE" id="PS50109"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50851"/>
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        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN59300.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="2226" mass="241035" checksum="01932CAAF1246FB0" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLH7</accession>
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        <submittedName>
            <fullName evidence="3">Nuclear transport factor 2 family protein</fullName>
        </submittedName>
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        <name evidence="2" type="ORF">GLE_4002</name>
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        <name type="scientific">Lysobacter enzymogenes</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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        <property type="gene ID" value="GLE_4002"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="10"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="133" mass="14806" checksum="68A22BC6E56AA45B" modified="2016-02-17" version="1">MGTSTQNEEIERLEKAFWQSILDGQPNIAAELLTEPALTISTHGVIKFDRAAYIKMASSDRVKLVDYSFSDMEVLFPTDQVAIITYRVAQTVEIDGETNEMDVYDSSTWIKASGRWLCVMHTETPAASAHGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLP0</accession>
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        <submittedName>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59412">
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        <property type="gene ID" value="GLE_4070"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="48" mass="4794" checksum="57CDD0423FEAB8E8" modified="2016-02-17" version="1">MGTHGSSGLIDRPGRSLDRGDLPQAARGGRGGSRAASASPAGGRDRTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM63</accession>
    <name>A0A0S2DM63_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter, ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_4245</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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        </lineage>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4245"/>
    <dbReference type="EnsemblBacteria" id="ALN59586">
        <property type="protein sequence ID" value="ALN59586"/>
        <property type="gene ID" value="GLE_4245"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4245"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4186"/>
    <dbReference type="OMA" id="DAYFQHK"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="entry name" value="ABC_KpsT_Wzt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10147">
        <property type="entry name" value="Wzt_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015860">
        <property type="entry name" value="ABC_transpr_TagH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029439">
        <property type="entry name" value="Wzt_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14524">
        <property type="entry name" value="Wzt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="26"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="59"/>
            <end position="66"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="418" mass="45571" checksum="2874D2583087A9A7" modified="2016-02-17" version="1">MSGPVMVVEKVGKSYVEYASELQRFARWFGIPVKPRHEHWVIRDVSFSVHQGESIGIIGQNGAGKSTLLKMITGTTKPSAGRVSVNGRVSALLELGLGFNGELTGRQNVVHAAGLMGLPQDQIEALMPQIEDFAEVGEYFDQAVRTYSSGMQMRVAFAVATAVRPDVLIVDEALSVGDTYFVHKCFKRIHEFRDAGTTLLIVSHDAVAIQALCDRAILLDGGKAVLDSDPYEVFDYYNALIAQRENSSVKTELSKDGKVATESGTGEAEIVDLQLLDEGGAPVEFVGVGHPVTLRARVRVHQTLERLVFGYMIRDRLGQALYGTNTHHTGQANEQLQAGSEVEFRVRFPANLGVGTYSFSVALTGAETHLQKNYQWRDLALVFTVANLDKPMFVGTAWIPPVIEVAASAAPARPEAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM76</accession>
    <name>A0A0S2DM76_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59602">
        <property type="protein sequence ID" value="ALN59602"/>
        <property type="gene ID" value="GLE_4261"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4261"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="100" mass="10712" checksum="F6DEA4C11FAB9D0F" modified="2016-02-17" version="1">MHAAVGQRRQWIALDRSRCEAPGRGGRQGPGAWRSGLRRGGGHGRDASMGGSAARSADLHAAQTAAIIPPLAFRIPQREAKFRRRLPAWAATGTSPTRHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM85</accession>
    <name>A0A0S2DM85_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TIGR02679 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_20940</name>
        <name evidence="3" type="ORF">GLE_4277</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4277"/>
    <dbReference type="EnsemblBacteria" id="ALN59618">
        <property type="protein sequence ID" value="ALN59618"/>
        <property type="gene ID" value="GLE_4277"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4277"/>
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    <dbReference type="OMA" id="DELSNWC"/>
    <dbReference type="OrthoDB" id="418702at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013495">
        <property type="entry name" value="CHP02679"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024466">
        <property type="entry name" value="CHP02679_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024465">
        <property type="entry name" value="DUF2399"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09664">
        <property type="entry name" value="DUF2399"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11796">
        <property type="entry name" value="DUF3323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02679">
        <property type="entry name" value="TIGR02679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3323" evidence="2">
        <location>
            <begin position="39"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2399" evidence="1">
        <location>
            <begin position="275"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="433" mass="46790" checksum="96041A3584FDDFB4" modified="2016-02-17" version="1">MSTPDARLRRLLGGPELAVVRQRLRRQFERIESDTPLVSVRLDQLDPDAHRALCQLSGKPSRLSRSMTLNIPDLDARLRSAGLADSLRDALEHLDGPIVSLAGSRRELQSRWAAVAKAPGLGPRLRAWLDESPAATGLLKRLGRDPERAEALLVAADAVLERLPATGMPRSQLAAETLGDAHALDSGKSVAALVQAGWRWHEGAAAGQTRAESEQAWVGRTAGEDADADAVIERPRDVWARAGVAVSELARPVLFLNLPVPYGGRCAWIAGEPGYLSLRQLLRDRPAWPVAGRSIHVCENPDIVAVAADRLGATCAPLVCTDGMPAAAQRILLGQLVSAGARLWYHGDYDWPGIGIGNFVIRTWRAAPWRFSAVDYRVAVAQAPSRARNLVGGMVEAQWDAELTAAMSERGLAIAEEAVVGQLLDDLRLDIDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMF7</accession>
    <name>A0A0S2DMF7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Vitamin B12-dependent ribonucleotide reductase</fullName>
            <ecNumber evidence="7">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BV903_03215</name>
        <name evidence="11" type="ORF">FE772_21720</name>
        <name evidence="9" type="ORF">GLE_4449</name>
    </gene>
    <organism evidence="9 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">C3</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>[thioredoxin]-disulfide + a 2'-deoxyribonucleoside 5'-diphosphate + H2O = [thioredoxin]-dithiol + a ribonucleoside 5'-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23252"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="EC" id="1.17.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 7">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the ribonucleoside diphosphate reductase class-2 family.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000006">
        <property type="protein sequence ID" value="OPD65318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949064.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4449"/>
    <dbReference type="EnsemblBacteria" id="ALN59790">
        <property type="protein sequence ID" value="ALN59790"/>
        <property type="gene ID" value="GLE_4449"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65318">
        <property type="protein sequence ID" value="OPD65318"/>
        <property type="gene ID" value="BV903_03215"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4449"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4386"/>
    <dbReference type="OMA" id="MMATMRC"/>
    <dbReference type="OrthoDB" id="357568at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02888">
        <property type="entry name" value="RNR_II_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000788">
        <property type="entry name" value="RNR_lg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013344">
        <property type="entry name" value="RNR_NrdJ/NrdZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02867">
        <property type="entry name" value="Ribonuc_red_lgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01183">
        <property type="entry name" value="RIBORDTASEM1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02504">
        <property type="entry name" value="NrdJ_Z"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="6 7" id="KW-0170">Cobalt</keyword>
    <keyword evidence="5 7" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RIBORED_LARGE" evidence="8">
        <location>
            <begin position="106"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN59790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD65318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW27877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="717" mass="80626" checksum="1F4C5C86C8A97E0F" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMG5</accession>
    <name>A0A0S2DMG5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4403</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4403"/>
    <dbReference type="EnsemblBacteria" id="ALN59744">
        <property type="protein sequence ID" value="ALN59744"/>
        <property type="gene ID" value="GLE_4403"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4403"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4342"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594972" evidence="1">
        <location>
            <begin position="41"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="258" mass="27765" checksum="1F1F1D2CDF8F3DE0" modified="2016-02-17" version="1">MVRVVMRPAMKRPAAAVRRVAACGGLALALACALAGPAWAGDAAAANATPADTVAASATVPDTQALVAEYKVRDARGERSLTLVRSADRIEYRQPGEPAELWRQTPDGIARLELFAAEKRSVAWAPGDLRTTGRMPQWEQLASPINPQLRDKLKRDGSAKVLGLSAERYRGESAEGQAIALEWLSAEGLPAYYRTGPAKPKAGDTGFYELKLVKLERVGAQTAFTATGDYRETDYADLGDMELDPFAAAYLKRNGHAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMG8</accession>
    <name>A0A0S2DMG8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_21365</name>
        <name evidence="3" type="ORF">GLE_4373</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 6">YC36</strain>
        </source>
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    <evidence type="ECO:0000313" key="3">
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    </evidence>
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    </evidence>
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</entry>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="61" mass="6579" checksum="FEC27D3BD12146D7" modified="2016-02-17" version="1">MTTAPGDGRRRRLRDGPDADAATASVGVFAVASSRRIAPLEGDCRDESDEYQWGNAMSFAF</sequence>
</entry>
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    <accession>A0A0S2DN85</accession>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60103.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="160" mass="17221" checksum="3EFE9CBD6570A594" modified="2016-02-17" version="1">MSRSETMSFAIVALLNFLTGCASTTGPEANSGLTVERILTEPLTGIAGMTRVKQDLSEIYGFDPSVDEYTNRDSKPLAGGWVLSQLWIEPSPADFISVSLATQPCFPVQRALSLTQAMPYQGSGELSAPMHNAIKNGMLVGLTSSPDGKCLRTIHIERDK</sequence>
</entry>
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    <accession>A0A0S2DNB1</accession>
    <name>A0A0S2DNB1_LYSEN</name>
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        <submittedName>
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    </protein>
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        <name evidence="8" type="primary">proY</name>
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    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 10">C3</strain>
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    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW28075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949259.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
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    <dbReference type="STRING" id="69.GLE_4721"/>
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    <dbReference type="KEGG" id="lez:GLE_4721"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
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        <property type="entry name" value="Amoino_acid_permease_CS"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00218">
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
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        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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    </feature>
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        <location>
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        </location>
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        <source>
            <dbReference type="EMBL" id="QCW28075.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="456" mass="48862" checksum="FCD7FACC87378D34" modified="2016-02-17" version="1">MPNDHQQLHRGLSERHIRLMALGAAIGVGLFLGSANAIKLAGPGILLAYLLGGGAIFIIMRALGEMAVHNPVAGSFSRYARDYLGPLSGYLTGWNYWFLWLVTCVAEITAVGVYMQVWFPGSPQWGWALAALVAMGSVNLITVKAYGEFEFWFAMIKVVTIVAMILGGLAMIVFGLGNNGVAIGISNLWAHGGFFPNGAQGVLMSLQMVMFAYLGVEMIGLTAGEAANPAKSIPDAINSVFWRIVIFYVGALFVILSLYPWNELGTTGSPFVQTFERLGIREAAGIINFVVLTAALSSCNGGIFSTGRMLYNLAQQKQAPALFARTSPGGVPRAAILVSVAALLIGVAANYLAPAKVFVWVTSIATFGAIWTWGVILVAHMKFRARLSAAERDALAFKAPMFPVGSWIALAFLVLVIGLMAYFPDTRVALIVGPAFLVLLTVLFYALGFHRRAAVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNF4</accession>
    <name>A0A0S2DNF4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59656">
        <property type="protein sequence ID" value="ALN59656"/>
        <property type="gene ID" value="GLE_4315"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4315"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4254"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="166" mass="17952" checksum="B914F360D99C2252" modified="2016-02-17" version="1">MRRFGHVIALGLAHPRAAQRPTSGHAARGCATTDLRSPANSGRLPEFAFHPRHVSPTARFSHGTFHPRQVSPTAHLPIRAVGASMHPPRAASERRVQSPPHANHAERHDSSQALRLSSIPMPTRHAAPARYAGLHAPPPVVSPIRYGGPRTHPHRARAPRLTAGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNZ6</accession>
    <name>A0A0S2DNZ6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Twin transmembrane helix small protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_10455</name>
        <name evidence="5" type="ORF">D9T17_05340</name>
        <name evidence="4" type="ORF">FE772_23425</name>
        <name evidence="2" type="ORF">GLE_4822</name>
    </gene>
    <organism evidence="2 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">C3</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 9" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000023">
        <property type="protein sequence ID" value="OPD64002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000015">
        <property type="protein sequence ID" value="ROU08213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949338.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4822"/>
    <dbReference type="EnsemblBacteria" id="ALN60163">
        <property type="protein sequence ID" value="ALN60163"/>
        <property type="gene ID" value="GLE_4822"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64002">
        <property type="protein sequence ID" value="OPD64002"/>
        <property type="gene ID" value="BV903_10455"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4822"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4753"/>
    <dbReference type="OrthoDB" id="2096992at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021313">
        <property type="entry name" value="DUF2909"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11137">
        <property type="entry name" value="DUF2909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU08213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="68" mass="7148" checksum="7FC6D130A89E7F5F" modified="2016-02-17" version="1">MKLLFVAAFLAVIVYNLGAGLYYMLVDKGTSKRTVNALTRRIGFSIALIALVVVGIATGVVQPHGVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP24</accession>
    <name>A0A0S2DP24_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4900"/>
    <dbReference type="EnsemblBacteria" id="ALN60241">
        <property type="protein sequence ID" value="ALN60241"/>
        <property type="gene ID" value="GLE_4900"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4900"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4831"/>
    <dbReference type="OMA" id="AFWRERP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="acidPPc" evidence="2">
        <location>
            <begin position="118"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="272" mass="29735" checksum="1A73BCDCD5DE1442" modified="2016-02-17" version="1">MIRSASRPLPSALPRPAVLPGISAGMSPRRFLLLHALWPLLTLAALSASTMGLGGDFWLADRFYALEGGRWALQNAYLTEQVIHRFGRDASTAAWLGAFAFWLYARSRPALAPWRRPLAYLLLATLLAVALASGLKSLTNMDCPWDLTRYGGEVPFFGLFDRRPSGLDRGVCFPAGHASGGYAWIALYFFFLQARPRLRWAGLATGLAVGLLFGFSQQLRGAHFLSHDVWTLAICWFVALALYLAMARREAPLAADKRGAPAARASLEGAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP66</accession>
    <name>A0A0S2DP66_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60356">
        <property type="protein sequence ID" value="ALN60356"/>
        <property type="gene ID" value="GLE_5015"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5015"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="46" mass="4989" checksum="67DFB19FF1A5AFC6" modified="2016-02-17" version="1">MGHDGSGRERTAADGPAAILGRPRRARHGPAVTRGWRRASALRRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPJ7</accession>
    <name>A0A0S2DPJ7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycerol-3-phosphate dehydrogenase [NAD(P)+]</fullName>
            <ecNumber evidence="7">1.1.1.94</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">NAD(P)H-dependent glycerol-3-phosphate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">gpsA</name>
        <name evidence="18" type="ORF">BV903_18290</name>
        <name evidence="17" type="ORF">GLE_5030</name>
    </gene>
    <organism evidence="17 19">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="17 19" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">C3</strain>
        </source>
    </reference>
    <reference evidence="18 20" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 20">B25</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>NAD(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:11092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.94"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 12">
            <text>NADP(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:11096"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.94"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7 13">Membrane lipid metabolism; glycerophospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 11">Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.94" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000049">
        <property type="protein sequence ID" value="OPD62485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949500.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000049.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5030"/>
    <dbReference type="EnsemblBacteria" id="ALN60371">
        <property type="protein sequence ID" value="ALN60371"/>
        <property type="gene ID" value="GLE_5030"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62485">
        <property type="protein sequence ID" value="OPD62485"/>
        <property type="gene ID" value="BV903_18290"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5030"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4958"/>
    <dbReference type="OMA" id="NRMFGNM"/>
    <dbReference type="OrthoDB" id="1419877at2"/>
    <dbReference type="UniPathway" id="UPA00940"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009331">
        <property type="term" value="C:glycerol-3-phosphate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004367">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase [NAD+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
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    </evidence>
    <sequence length="345" mass="36069" checksum="B3D5D833489327D8" modified="2016-02-17" version="1">MTSQTTTPKPRVAVLGAGSWGTALAALIARHGHPTVLWGRDADVAAAIDSRHENPRYLPGIALPDALRATTDLPAALAHADLVLVVTPSHAFAETLRALAPHRPAHAGVAWATKGFEPGSGRFLHEVAEETLGAGVPLAVVTGPSFAKEVAQGLPTALTVHSEDADFAQSVADALHGPAFRAYTGDDMLGAELGGAMKNVLAVATGVADGMQLGLNARAGLITRGLNEMLRLNQAIGGQPETLMGLAGLGDLVLTCTGDLSRNRRLGLALGRGQSIEDAVREIGQVVESVQTADEVMRQAERHGIELPISSAVREVLHGRITPSDGLRQLLAREQKPEYPNDLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Feng T."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW28494.1"/>
        </source>
    </evidence>
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    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="208" mass="20354" checksum="68F009D4B92F8339" modified="2016-02-17" version="1">MRKFPTALLAASLLAGLPLLAQAESQYSTGTASPITATARLDFQITVPKILFLRVGAGADYSNTATINQIAFAVPAANLGSGAAVAATAASGDLGNGGVTAKLVGNNGTITLSSSTVGALGNGAGDSISYSQIQTSVATNTTATALPAPALADGAVTSSTVAPGAGGKVVNLDAKWTYAYLNGAVVAPGTYGGVNANNSRVTYTASMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPW4</accession>
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        <name evidence="6" type="ORF">BV903_24970</name>
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        </lineage>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="OPD61189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="QCW28488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="protein sequence ID" value="ALN60588"/>
        <property type="gene ID" value="GLE_5247"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD61189"/>
        <property type="gene ID" value="BV903_24970"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="P:regulation of transcription, DNA-templated"/>
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
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    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
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        <property type="entry name" value="WH-like_DNA-bd_sf"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="124"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="124"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD61189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW28488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="221" mass="23949" checksum="EFFC257CB84946BE" modified="2016-02-17" version="1">MNILLVEDDAMLAEAVRTGLGHDGWRVDWVADAPLAKTALVDHDFDAVVLDLGLPGGSGLGVLGALRNRYDATPVLIVTARDKLSERIAGLDAGADDYIVKPFQLDELCARLRAVMRRSQGRVSPVLSCGAVVLDPARRLVTRDGEPVTLSGHEFRTLTLLLERQGRVVTREQLEEAVYGSSGTIESNTIAVYVHQLRRKLGEQLIVTVHGYGYRVGGGPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPX2</accession>
    <name>A0A0S2DPX2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Type III secretion apparatus protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">epaP</name>
        <name evidence="8" type="ORF">GLE_5120</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FliP/MopC/SpaP family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5120"/>
    <dbReference type="EnsemblBacteria" id="ALN60461">
        <property type="protein sequence ID" value="ALN60461"/>
        <property type="gene ID" value="GLE_5120"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5120"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5045"/>
    <dbReference type="OMA" id="GMQMVSP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005838">
        <property type="entry name" value="T3SS_IM_P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30587">
        <property type="entry name" value="PTHR30587"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00813">
        <property type="entry name" value="FliP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01302">
        <property type="entry name" value="TYPE3IMPPROT"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01060">
        <property type="entry name" value="FLIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01061">
        <property type="entry name" value="FLIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="249"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN60461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="307" mass="31102" checksum="A802A6EEE446AF04" modified="2016-02-17" version="1">MDFSSFSPALVLLTVVSLALAPFVAVMVTSFTKIVVVLSLLRNALGLQQVPPNVVINGLAIVLSIYVMYPVILETHDAINASANGTTVAATQTPPAANATTATGAAPAAATATAGAAAPAAGNAAPAAATATTAPAAAASSAPAANAAATAPAGAQPAAAAKRPAPTPSSVLGGKMDAARLLQLMDAGKEPLRKFLIKHSSDAERAFFLRSAQRLLPPNARADIGVDDFIVVIPAFTVSELTAAFQIGFLIFLPFLIIDLVVSNILLSLGMMMLSPTTVSLPFKLLLFVLIGGWAKLVHGLVLTYGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ41</accession>
    <name>A0A0S2DQ41_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_00280</name>
        <name evidence="2" type="ORF">GLE_5401</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949781.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60742">
        <property type="protein sequence ID" value="ALN60742"/>
        <property type="gene ID" value="GLE_5401"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5401"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5316"/>
    <dbReference type="OrthoDB" id="2219784at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242223" evidence="1">
        <location>
            <begin position="27"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="70" mass="7768" checksum="838C0FAB1CAAC2C0" modified="2016-02-17" version="1">MRSIRRTTLFLALSVFAAGFAGSAFAQRDCSWCTAIYDACMVQPDANQGQCAREHNYCAEPINCPLMPEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQB4</accession>
    <name>A0A0S2DQB4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5260"/>
    <dbReference type="EnsemblBacteria" id="ALN60601">
        <property type="protein sequence ID" value="ALN60601"/>
        <property type="gene ID" value="GLE_5260"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5260"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5179"/>
    <dbReference type="OMA" id="GSCRPWV"/>
    <dbReference type="OrthoDB" id="1105091at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595972" evidence="1">
        <location>
            <begin position="25"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="266" mass="28230" checksum="8EE7579B44851691" modified="2016-02-17" version="1">MRSLVRRFAVLCLPLALLPAAAGAQGFSALVSPPRFEDRAKPGSVYRNVVEITNVSARAARYTLKTADWTMDAHGAVAFDTALAPGSCRPWVGLEAAQIDVAANGKRRYRFEVAVPADAPAGECRFAILLEGEPESAGGALALPVSGRIGIIVYLAVGEAAARLHVVETTTAQVDGQRVPVLRVRNEGNAHTRLEGLIDGIDASGRRYGLQPSSLPILPGETRTLALTPQADDADSAPPALAYPLQLKGALEWDRQTLPLDLRLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQH4</accession>
    <name>A0A0S2DQH4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nuclear transport factor 2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_25535</name>
        <name evidence="2" type="ORF">GLE_5280</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5280"/>
    <dbReference type="EnsemblBacteria" id="ALN60621">
        <property type="protein sequence ID" value="ALN60621"/>
        <property type="gene ID" value="GLE_5280"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5280"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5198"/>
    <dbReference type="OMA" id="TPWFVDY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039437">
        <property type="entry name" value="Put_lumazine-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12893">
        <property type="entry name" value="Lumazine_bd_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242475" evidence="1">
        <location>
            <begin position="25"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="161" mass="17264" checksum="1F1B266C5E0B5383" modified="2016-02-17" version="1">MTAYAPLRHLAAVAVLAAAPAAFAAPADAASAGIDPATRAAIEATCFDYLDGQLEGDPARVARSLHPDLAKRRVLGATADETLGLRRMSKDELVELTRQGALKTPKAQWNRSCAALDVAGNVAVARAETPWFVDFFHLGKFGERWVIVNALWYAKPKPVEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQT0</accession>
    <name>A0A0S2DQT0_LYSEN</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5452</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60793">
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        <property type="gene ID" value="GLE_5452"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5452"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5367"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="42" mass="4949" checksum="433642E009BF7EB1" modified="2016-02-17" version="1">MIARHRASRRRAPRRHCIFLQARRRFATAIGNCPAFAPQQRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQY9</accession>
    <name>A0A0S2DQY9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Site-specific recombinase, resolvase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5535"/>
    <dbReference type="EnsemblBacteria" id="ALN60876">
        <property type="protein sequence ID" value="ALN60876"/>
        <property type="gene ID" value="GLE_5535"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5535"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5454"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="88" mass="9634" checksum="FC077ED3A046A3B7" modified="2016-02-17" version="1">MGRIEGRASTSLPREVARNPRLDEAKVTVAMAQVDRLWDLLGPAEQTRLLRQLVNKVTVGNDTLEVHLRAGGLRATADEMQARTEAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DR20</accession>
    <name>A0A0S2DR20_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phage/plasmid primase, P4 family, C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_5504</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5504"/>
    <dbReference type="EnsemblBacteria" id="ALN60845">
        <property type="protein sequence ID" value="ALN60845"/>
        <property type="gene ID" value="GLE_5504"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5504"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5419"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006500">
        <property type="entry name" value="DNA_primase_phage/plasmid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045455">
        <property type="entry name" value="DUF5906"/>
    </dbReference>
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        <property type="entry name" value="Helicase_SF3_DNA-vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014818">
        <property type="entry name" value="Phage/plasmid_primase_P4_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08706">
        <property type="entry name" value="D5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DUF5906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00885">
        <property type="entry name" value="D5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01613">
        <property type="entry name" value="primase_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SF3_HELICASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SF3 helicase" evidence="2">
        <location>
            <begin position="205"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="341" mass="37951" checksum="5CCDBB8F44E6E708" modified="2016-02-17" version="1">MLHLPEDKPQGWDAADAAADGFDIEGFIRAGERTFLSAGTDEAPPSVDFEGLDWTSDDGLGLAFSRRYAEDWRYCAAWGQWLSWTGSRWNPDRTLVVQHLVRGVCRAASALAERPSQRSKLASSSTVAGVERLARSDPRHSSSAQEWDSDVWALNTPIGTVDLRTGAMRRHARADRLTRMATAGMGRDSPLWRRFLADVTGGDEQMQTYLQRMAGYCLTGVTTEHALFFLYGTGANGKSVFVNTLTSILGDYATSAPMDTFMESRGERHPTELAGLRGARFVSAVETEEGRRWNESKLKAITGGDKIMARFMRQDFFEYIPQFKLVIAGNHKPAIRNVDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-06-16" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>C3PTT4</accession>
    <name>C3PTT4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HSAF FAD dependent oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">NAD(P)/FAD-dependent oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Ox2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_15980</name>
        <name evidence="5" type="ORF">GLE_3217</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2007" name="Antimicrob. Agents Chemother." volume="51" first="64" last="72">
            <title>Structure and biosynthesis of heat-stable antifungal factor (HSAF), a broad-spectrum antimycotic with a novel mode of action.</title>
            <authorList>
                <person name="Yu F."/>
                <person name="Zaleta-Rivera K."/>
                <person name="Zhu X."/>
                <person name="Huffman J."/>
                <person name="Millet J.C."/>
                <person name="Harris S.D."/>
                <person name="Yuen G."/>
                <person name="Li X.C."/>
                <person name="Du L."/>
            </authorList>
            <dbReference type="PubMed" id="17074795"/>
            <dbReference type="DOI" id="10.1128/AAC.00931-06"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">C3</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2009-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Du L."/>
                <person name="Xie Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="3">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="EF028635">
        <property type="protein sequence ID" value="ACP19699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948130.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3217"/>
    <dbReference type="EnsemblBacteria" id="ALN58563">
        <property type="protein sequence ID" value="ALN58563"/>
        <property type="gene ID" value="GLE_3217"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3217"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3171"/>
    <dbReference type="OrthoDB" id="418913at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016116">
        <property type="term" value="P:carotenoid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="CrtISO-like"/>
    </dbReference>
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        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <feature type="domain" description="Amino_oxidase" evidence="3">
        <location>
            <begin position="30"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACP19699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW26911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="578" mass="64514" checksum="CCC0FE845660D136" modified="2009-06-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA33</accession>
    <name>A0A0S2DA33_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0039</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55398">
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        <property type="gene ID" value="GLE_0039"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0039"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.46"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="38" mass="4159" checksum="21AC1082DA378C40" modified="2016-02-17" version="1">MARLGRMGISASAVAGALGDTRMRSLGRQLWEQRRSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAM6</accession>
    <name>A0A0S2DAM6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0207</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55566">
        <property type="protein sequence ID" value="ALN55566"/>
        <property type="gene ID" value="GLE_0207"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0207"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.209"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="55" mass="5685" checksum="876806ACFED3F8B8" modified="2016-02-17" version="1">MARVRIHAHALRGCGTTASGLGASTSESNGNTNGNNESKWIPAFAGMTAGDPRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAQ9</accession>
    <name>A0A0S2DAQ9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Anhydro-N-acetylmuramic acid kinase</fullName>
            <ecNumber evidence="1">2.7.1.170</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">AnhMurNAc kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 2" type="primary">anmK</name>
        <name evidence="2" type="ORF">GLE_0262</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1,6-anhydro-N-acetyl-beta-muramate + ATP + H2O = ADP + H(+) + N-acetyl-D-muramate 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:24952"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58690"/>
            <dbReference type="ChEBI" id="CHEBI:58722"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.170"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-sugar metabolism; 1,6-anhydro-N-acetylmuramate degradation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan recycling.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the anhydro-N-acetylmuramic acid kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.170" evidence="1"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0262"/>
    <dbReference type="EnsemblBacteria" id="ALN55621">
        <property type="protein sequence ID" value="ALN55621"/>
        <property type="gene ID" value="GLE_0262"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0262"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.263"/>
    <dbReference type="OMA" id="GQTIRHE"/>
    <dbReference type="UniPathway" id="UPA00343"/>
    <dbReference type="UniPathway" id="UPA00544"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097175">
        <property type="term" value="P:1,6-anhydro-N-acetyl-beta-muramic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006040">
        <property type="term" value="P:amino sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009254">
        <property type="term" value="P:peptidoglycan turnover"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01270">
        <property type="entry name" value="AnhMurNAc_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005338">
        <property type="entry name" value="Anhydro_N_Ac-Mur_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30605">
        <property type="entry name" value="PTHR30605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03702">
        <property type="entry name" value="AnmK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 2" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="4"/>
            <end position="11"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="369" mass="38284" checksum="84626BB585EB89AC" modified="2016-02-17" version="1">MISGTSADGIDAALVRFEAGAAPTRCELVIGRTYAWDAALRERLVALGQGGDARSLEELGTLDIQTAEAFAAAARALLEDAGVAPGEVAAIGSHGQTVRHRPAGAAFDGRHPFTWQIGDGAVIAERCGIATVADFRRRDVAAGGHGAPLMPAFHAALLGSPDEDRAALNLGGIANFTLLPAHGAVRGFDTGPANCLMDAWALRHLGTAFDADGAFAARGEVDPALLARLLDEPWFALPPPKSTGREQFQLDWVEARLGGGERPQDVQATLLELSAVTIAQALRAQQPATRRVLACGGGVRNGALLARLAERLPGVAVETTQAYGLDPDFVEAMGFAWLARQTLAGLPGNLPSVTGARGLRVLGTVHPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBC4</accession>
    <name>A0A0S2DBC4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cardiolipin synthase B</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Phospholipase D Active site motif</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_02725</name>
        <name evidence="3" type="ORF">GLE_0387</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945995.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0387"/>
    <dbReference type="EnsemblBacteria" id="ALN55745">
        <property type="protein sequence ID" value="ALN55745"/>
        <property type="gene ID" value="GLE_0387"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0387"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.384"/>
    <dbReference type="OMA" id="HASRSYF"/>
    <dbReference type="OrthoDB" id="1881748at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019637">
        <property type="term" value="P:organophosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="2">
        <location>
            <begin position="170"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="2">
        <location>
            <begin position="347"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="434" mass="49351" checksum="28D5320CCED7D74E" modified="2016-02-17" version="1">MGILERKRWTRRQVGAWLLGAVLTTALVAWIAVNLAGPEKRIQRLPEHRYGVEDPQFRREMSIMLGPGIVAGNEVVDLQNGDEIFPAMLEAIAAARRSITFETYIYWSGEVGRRFSRALAERARAGVEVRLTVDWLGSAKMDADLLDEMRSAGVQIERYRPLDWYSWDRFNNRTHRKLLVVDGAVAFTGGVGIADQWRGHAQDPEHWREAHFRLRGPAAGQFQAAFNDNWIKMTGRPLSGPAYFPSLAPVGGVDAQMFLSSPTSGSESMHLMYLMSLTAARRSIDLSASYFVPDELIVQALLRARLRGVRVRILVPGEHTDSETVRLASKAQWGALLAAGVEFHEYRPTMMHVKMLIVDDYLVSVGSTNFDIRSFRLNDEASLNVYDRGFAQRMRRVFESDLARSRPYTRDAWLQRPWHQRVREALVRPLRSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBM8</accession>
    <name>A0A0S2DBM8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55929">
        <property type="protein sequence ID" value="ALN55929"/>
        <property type="gene ID" value="GLE_0571"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0571"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="91" mass="9901" checksum="DC32C31AB195B7B8" modified="2016-02-17" version="1">MRGRALATAASLVRIARKDRRRPSHRTVEAQARTGRWRAATATHANASAARTPPRRCVRLSPPHRRRPGTATGGAEPGTPSDQGDKVKFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBW5</accession>
    <name>A0A0S2DBW5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_0527</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946098.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0527"/>
    <dbReference type="EnsemblBacteria" id="ALN55885">
        <property type="protein sequence ID" value="ALN55885"/>
        <property type="gene ID" value="GLE_0527"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0527"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.522"/>
    <dbReference type="OMA" id="NPEGHRY"/>
    <dbReference type="OrthoDB" id="330793at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006093">
        <property type="entry name" value="Oxy_OxRdtase_FAD_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00862">
        <property type="entry name" value="OX2_COVAL_FAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="3">
        <location>
            <begin position="46"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN55885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="456" mass="50204" checksum="B7EEF306F29C07BD" modified="2016-02-17" version="1">MDPRRDPIDADDFRIFPRHLDGKARSRHHAEYAGWHRSACWNGRRFERFPEYIVRAQSVADVAHSIDFARRHRLPVSVRGRGHSYAGCFLRDDGLLLDLAALDRIDVDAAARLAAVQPGASSRQLAQALAPHGLAFPTGHGGDVGLSGFLLGGGLGINFRAWGGISAFNVRAIDLIGADGDLLHADAEHHPELFWAARGGGPGLGFVVVKFYLDCRPLPRCITSTCARTGLDRLGELLQAIERADPEPALQVMVAVVPDGDGLQASLSALAFADTPRQAQALHASLFANLPAGLLEPPAQDQPSGFEAIYRQSEAMLVSRRYRSDNILTDRAGEAARILAAHLPARPSPATVPLLIWRGEPRLPDAAFSARGRWFVSTYAQWDAERDDEANRRWLKALYDELAGVASGAYINEFDLEERSDRVERCFAPANWARLRELRRRCDPDGAFHDVRIGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC07</accession>
    <name>A0A0S2DC07_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cyd operon protein YbgT</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Cytochrome bd-I oxidase subunit CydX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ybgT</name>
        <name evidence="2" type="synonym">cydX</name>
        <name evidence="2" type="ORF">FE772_03910</name>
        <name evidence="1" type="ORF">GLE_0641</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0641"/>
    <dbReference type="EnsemblBacteria" id="ALN55999">
        <property type="protein sequence ID" value="ALN55999"/>
        <property type="gene ID" value="GLE_0641"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0641"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.630"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011724">
        <property type="entry name" value="Cyd_oper_YbgT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012994">
        <property type="entry name" value="YbgT_YccB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08173">
        <property type="entry name" value="YbgT_YccB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02106">
        <property type="entry name" value="cyd_oper_ybgT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="41" mass="4870" checksum="7743039EE7D36EC7" modified="2016-02-17" version="1">MWYFAWILGLALACSFGVLNAMWFEMREDDDQSRAQARRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC11</accession>
    <name>A0A0S2DC11_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="8">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">aceF</name>
        <name evidence="13" type="ORF">FE772_04065</name>
        <name evidence="12" type="ORF">GLE_0675</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">C3</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + acetyl-CoA = (R)-N(6)-(S(8)-acetyldihydrolipoyl)-L-lysyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:17017"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="2.3.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Forms a 24-polypeptide structural core with octahedral symmetry.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946206.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0675"/>
    <dbReference type="EnsemblBacteria" id="ALN56033">
        <property type="protein sequence ID" value="ALN56033"/>
        <property type="gene ID" value="GLE_0675"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0675"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.663"/>
    <dbReference type="OMA" id="TMEFESF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004742">
        <property type="term" value="F:dihydrolipoyllysine-residue acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006256">
        <property type="entry name" value="AcTrfase_Pyrv_DH_cplx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43178:SF2">
        <property type="entry name" value="PTHR43178:SF2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 8" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="10">
        <location>
            <begin position="4"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="11">
        <location>
            <begin position="169"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="81"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN56033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW24969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="474" mass="49155" checksum="E932848998562C4C" modified="2016-02-17" version="1">MADLKEARVPDIGDYDGVPVIELLVAVGDTVTQDQGLVTLESDKATMEVPAPFAGIVRELKVKLGDQLAEGSVVALIEPTEGDAKQAPAPAQEAAKPAAPAKAEAPAKAEAPAPAKSEPAPAPKAEAPQPAAPAPLPGAAAGTDPEALPPRTPPVAFTAEELMPDKVPYASPAVRLFARELGVDLTRVSGSARGGRISKEDVQSFVKGVMQGGGGAPAAAGAAPALGGGLNLLPWPKVDFSKFGEVETKPLTRIQKLSGANLARNWAMIPHVTQHDDADITDLEALRVALNKENEKAGIKLTMLAFLMKASVNALQKFPTFNASLDASGENLTLKKYFHIGFAADTPNGLVVPVVRDVDKKGVLQIARETGELAAKARDGKLGPADMSGGCFSISSLGGIGGTAFTPIVNAPEVAILGVSKSATKPVWDGKQFAPRLILPLSLSYDHRVIDGAAAARFTAYLAQLLADMRRSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCI1</accession>
    <name>A0A0S2DCI1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF262 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0703</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56061">
        <property type="protein sequence ID" value="ALN56061"/>
        <property type="gene ID" value="GLE_0703"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0703"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.691"/>
    <dbReference type="OMA" id="IQREFVW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004919">
        <property type="entry name" value="DUF262"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03235">
        <property type="entry name" value="DUF262"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF262" evidence="2">
        <location>
            <begin position="111"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="685" mass="76170" checksum="FAF0F0CCF16F66F9" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCK8</accession>
    <name>A0A0S2DCK8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0714</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56072">
        <property type="protein sequence ID" value="ALN56072"/>
        <property type="gene ID" value="GLE_0714"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0714"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.702"/>
    <dbReference type="OMA" id="WHRIGAL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="304" mass="33235" checksum="01FADB2807D8DC79" modified="2016-02-17" version="1">MSAAAPVCPPRIAPARVAAADRRPYFIASDVVLDGQRLRDRNGFVTALGVRALRRAGLPVPAAMLDALQQCRSARGGFRFWPERAHPDWAPRLPDDADDTAIMLLELLRAGRISHADAHRTACLAIARRRIAQLPLLRPPWLRVGVFATWSRDGIRRDLVDCTATANVLALFAHLRLAHLPGVREAAGMLAAALRWAGDDELRAASLSPFYPDPAEFVLALEHAAECGAPTADELHRLAATTAWGRDAPARSERADHAVCGSPYGMAAWRSPELARLRAWARRSGAMRHRDLQAELDEQITAMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCU7</accession>
    <name>A0A0S2DCU7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase, M28 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLE_0999</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Golgi apparatus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Lysosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Secreted</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0999"/>
    <dbReference type="EnsemblBacteria" id="ALN56357">
        <property type="protein sequence ID" value="ALN56357"/>
        <property type="gene ID" value="GLE_0999"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0999"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.987"/>
    <dbReference type="OMA" id="LFMNEEN"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039866">
        <property type="entry name" value="CPQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12053">
        <property type="entry name" value="PTHR12053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595325" evidence="7">
        <location>
            <begin position="21"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M28" evidence="8">
        <location>
            <begin position="263"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="475" mass="49381" checksum="766761F8F5F1AE77" modified="2016-02-17" version="1">MRAPLWAAMAAVLFTGSILAGDAAAAQRETRIPQAAVDAAGELRERALASDLGFKITESLTTEVGPRLAGSEADARAVAWAQAKFRELGFDKVWTEPVTFPKWQRRSEHAEVLGASAQPLRLTALGGSPGGTVEGEVVRFADLAALEAAPAGSLAGKIAFVDYVMQRAKDGAGYGPGGRVRGRGPSAAIRAGAAGFLMRSAGTDSHRMPHTGITRFDEGLTPVPSAALSAPDADQLARLTARGATRVRVALDCGWDGQATSYNVIGEIRGKGKPDEVVIIGGHLDSWDQGTGAIDDAAGVGLTMAAAKLIGQSKLRPARTVRVIAFANEEQGLYGGKAYADKHAADVRKHQIGAESDFGAGRIYAYSSSAPDYAQAADKQIADALAPLGIEHTPGKGGPGPDIGPFAAKGLAWARLAQDGSDYFDYHHTPDDTLDKIDPKALAQNVAAYAVFAYLAASADGDFGSAPKQVSPPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD32</accession>
    <name>A0A0S2DD32_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56433">
        <property type="protein sequence ID" value="ALN56433"/>
        <property type="gene ID" value="GLE_1075"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1075"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1063"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="67" mass="7293" checksum="DA732F9741861596" modified="2016-02-17" version="1">MLFFPPRRTCLATCAGSATEPFSQPEPKASGLKPLPQQSASLPWRRDLRRGVPVGGPSGPMLFFPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD35</accession>
    <name>A0A0S2DD35_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Acyl-coenzyme A dehydrogenase</fullName>
            <ecNumber evidence="6">1.3.8.7</ecNumber>
            <ecNumber evidence="7">1.3.8.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">FE772_06035</name>
        <name evidence="14" type="ORF">GLE_1096</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">C3</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a long-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = a long-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:17721"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:83721"/>
            <dbReference type="ChEBI" id="CHEBI:83727"/>
            <dbReference type="EC" id="1.3.8.8"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a medium-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron-transfer flavoprotein] = a medium-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:14477"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:83723"/>
            <dbReference type="ChEBI" id="CHEBI:83726"/>
            <dbReference type="EC" id="1.3.8.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.3.8.7" evidence="6"/>
    <dbReference type="EC" id="1.3.8.8" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946523.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1096"/>
    <dbReference type="EnsemblBacteria" id="ALN56454">
        <property type="protein sequence ID" value="ALN56454"/>
        <property type="gene ID" value="GLE_1096"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1096"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1083"/>
    <dbReference type="OMA" id="SAYAHSQ"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="UniPathway" id="UPA00659"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004466">
        <property type="term" value="F:long-chain-acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033539">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA dehydrogenase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015396">
        <property type="entry name" value="DUF1974"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09317">
        <property type="entry name" value="DUF1974"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0274">FAD</keyword>
    <keyword evidence="9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="27"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="12">
        <location>
            <begin position="154"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="11">
        <location>
            <begin position="364"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1974" evidence="13">
        <location>
            <begin position="518"/>
            <end position="801"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00020144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF09317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN56454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW25286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="827" mass="89817" checksum="379B6D066397CD9E" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD79</accession>
    <name>A0A0S2DD79_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Molybdenum transport system permease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">modB</name>
        <name evidence="12" type="ORF">FE772_05410</name>
        <name evidence="11" type="ORF">GLE_0954</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946420.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0954"/>
    <dbReference type="EnsemblBacteria" id="ALN56312">
        <property type="protein sequence ID" value="ALN56312"/>
        <property type="gene ID" value="GLE_0954"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0954"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.941"/>
    <dbReference type="OMA" id="MYSFIET"/>
    <dbReference type="OrthoDB" id="1915735at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015098">
        <property type="term" value="F:molybdate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011867">
        <property type="entry name" value="ModB_ABC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02141">
        <property type="entry name" value="modB_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 9" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="97"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="16"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN56312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW25180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="234" mass="24581" checksum="CBA5B983DD21C08D" modified="2016-02-17" version="1">MNEGFAGFSAAELTAIALSLKVAAAATVCSLPFGVAVGWLLARTRFPGKLLVDTLMYLPLVLPPVVTGYALLLGFSAQGPIGRVLSEHFGIVFAFRWTGAALASAIMGFPLMVRAIRLSIEAVDRRLEQAAATLGANPWRVFFGVTLPLAWPGLLAGAVLCFAKALGEFGATITFVSNIAGETQTLSSAIWGLMQTPGAESGVLRLALVAVALSFAAVFASEWLVQRQRAGTQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD81</accession>
    <name>A0A0S2DD81_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1172</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56530">
        <property type="protein sequence ID" value="ALN56530"/>
        <property type="gene ID" value="GLE_1172"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1172"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1157"/>
    <dbReference type="OMA" id="KYSQHNP"/>
    <dbReference type="OrthoDB" id="1165188at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="371" mass="41839" checksum="8E8C342783F0D7DD" modified="2016-02-17" version="1">MNAAARVADETFSQRAHAFARIHVGADSRALVANLDTHAELIDDGERSYPVSIDDGEAQDNAWVCSPRTTYGAYATEEALRYAPALLGAPIRAAGLGLDRWLRGARIDRAVAINNWWLSTNLYPRWRIGCAQRLLQGALQRWPGHAVWLRSLNRDDHADWLEECDRLGFLLIPSRQVYLFRDVAALAQRRHNLQIDLRLARKQPRRAGDGDIGGADYARIAWLYARLYMDRYSRCNPRYTEAFVRSWHRAGLLQLDGFRDEAGQLMCIAGIFRQGRTLTTPIVGYDTDQPQRLGLYRLLTATTFERAIASGDAINFSAGAAGFKRLRGGQPSIEYSAVYARHLPARTQRALGWLSALTRRAGVPIMRRFEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD86</accession>
    <name>A0A0S2DD86_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Pyrroline-5-carboxylate reductase</fullName>
            <shortName evidence="3">P5C reductase</shortName>
            <shortName evidence="3">P5CR</shortName>
            <ecNumber evidence="3 4">1.5.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">PCA reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 7" type="primary">proC</name>
        <name evidence="7" type="ORF">GLE_1160</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-proline + NAD(+) = 1-pyrroline-5-carboxylate + 2 H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:14105"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15893"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>L-proline + NADP(+) = 1-pyrroline-5-carboxylate + 2 H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:14109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15893"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the pyrroline-5-carboxylate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.2" evidence="3 4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946563.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1160"/>
    <dbReference type="EnsemblBacteria" id="ALN56518">
        <property type="protein sequence ID" value="ALN56518"/>
        <property type="gene ID" value="GLE_1160"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1160"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1145"/>
    <dbReference type="OMA" id="VVRVMTN"/>
    <dbReference type="OrthoDB" id="1349288at2"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00361"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004735">
        <property type="term" value="F:pyrroline-5-carboxylate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01925">
        <property type="entry name" value="P5C_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029036">
        <property type="entry name" value="P5CR_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000304">
        <property type="entry name" value="Pyrroline-COOH_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645">
        <property type="entry name" value="PTHR11645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14748">
        <property type="entry name" value="P5CR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000193">
        <property type="entry name" value="Pyrrol-5-carb_rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00112">
        <property type="entry name" value="proC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00521">
        <property type="entry name" value="P5CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0521">NADP</keyword>
    <keyword evidence="2 3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 4" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F420_oxidored" evidence="5">
        <location>
            <begin position="12"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="P5CR_dimer" evidence="6">
        <location>
            <begin position="169"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN56518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="278" mass="28296" checksum="FF3FDA3F66833CD7" modified="2016-02-17" version="1">MSDATPPFSAPIAFVGGGNMARSLIGGLIARGADPARIRVAEPVPALREALARDFGVPVFERGEDAVEGAQVWLLAVKPQVMREVCGSLAAQARAQAPLAISIAAGITAGQLDRWLGGGAAVVRAMPNTPALLGAGITGLYANDAARPRFDQAAELLSAVGPTVRIDDETQMDAVTAVSGSGPAYVFLLAEAMQQAGEAQGLDSDAARALVVQTLLGAATMLRGSEESAATLRARVTSPGGTTQAAVETFEAGGLRELVARAIAAATERGRQLSAANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD87</accession>
    <name>A0A0S2DD87_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type IV pili twitching motility protein PilT</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Type IV pilus assembly protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Type IV pilus twitching motility protein PilT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pilT</name>
        <name evidence="4" type="ORF">BV903_16275</name>
        <name evidence="5" type="ORF">FE772_06340</name>
        <name evidence="3" type="ORF">GLE_1163</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000043">
        <property type="protein sequence ID" value="OPD62837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946565.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1163"/>
    <dbReference type="EnsemblBacteria" id="ALN56521">
        <property type="protein sequence ID" value="ALN56521"/>
        <property type="gene ID" value="GLE_1163"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62837">
        <property type="protein sequence ID" value="OPD62837"/>
        <property type="gene ID" value="BV903_16275"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1163"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1148"/>
    <dbReference type="OMA" id="WELDCSY"/>
    <dbReference type="OrthoDB" id="473670at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01131">
        <property type="entry name" value="PilT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006321">
        <property type="entry name" value="PilT/PilU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01420">
        <property type="entry name" value="pilT_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="193"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD62837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="345" mass="38500" checksum="6F89F7C6E1601EE8" modified="2016-02-17" version="1">MDIAELLAFSVKNKASDLHLSAGLPPMIRVDGDVRRINIPALDHKQVHALVYDIMSDKQRRDFEEFLEVDFSFEIPGLARFRVNAFNQNRGAGAVFRTIPSEVLSLEDLGCPPIFRQLIEQPQGLILVTGPTGSGKSTTLAAMIDHINKNEYAHILSVEDPIEFVHTSQKCLINQREVHRDTHGFNEALRSALREDPDYILVGELRDLETIRLALTAAETGHLVFGTLHTSSAAKTVDRIIDVFPAGEKPMVRSMLSESLRAVISQALLKKVGGGRTAAWEIMVGIPAIRNLIREDKVAQMYSAIQTGQAYGMMTLDQHLQDLVKRGLILRPQAKEYAKDKRLFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDJ8</accession>
    <name>A0A0S2DDJ8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_06610</name>
        <name evidence="2" type="ORF">GLE_1219</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946608.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56576">
        <property type="protein sequence ID" value="ALN56576"/>
        <property type="gene ID" value="GLE_1219"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1219"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1204"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="162" mass="17291" checksum="8BFBB03640136656" modified="2016-02-17" version="1">MENAPPDAVSSSHAGKRLSILATLSIATIFPGLLFALLRVGRNCAIQDIFAGDNEAASLKLFSVTLIYAGAALALSRLNRRLGFYPVLGAVPVLIGVAAVYGFPLALVPAGLLAIVSFLMWKGRYHCAPIQKWLAIALLVPGAFAVLIIVLNIRMELLYRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDN0</accession>
    <name>A0A0S2DDN0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membrane dipeptidase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Renal dipeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_07215</name>
        <name evidence="2" type="ORF">GLE_1358</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946715.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1358"/>
    <dbReference type="EnsemblBacteria" id="ALN56715">
        <property type="protein sequence ID" value="ALN56715"/>
        <property type="gene ID" value="GLE_1358"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1358"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1340"/>
    <dbReference type="OMA" id="KHIFHIA"/>
    <dbReference type="OrthoDB" id="1145595at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01301">
        <property type="entry name" value="rDP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008257">
        <property type="entry name" value="Pept_M19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443">
        <property type="entry name" value="PTHR10443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01244">
        <property type="entry name" value="Peptidase_M19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51365">
        <property type="entry name" value="RENAL_DIPEPTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242146" evidence="1">
        <location>
            <begin position="20"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="401" mass="43355" checksum="A1F01373C0B19081" modified="2016-02-17" version="1">MRIAALALALALAPLAAHADQPLSAGQRFAQDAIIVDTHIDAPTGLLRHWADLGLDTPKVEFDYPRARQGGLDIAFMSIYTSPGEDAAGTATQTAHTQIDAVEAMVGRRPEQFAVLRSPKDFERLNAHNQRVLLALGMENGAPIGDDLSRLKLFFDRGVRYITLAHSEDNRISDSSYSRKRTWKGLSPFGEKVVDEMNRLGIMVDVSHLSDDAVRDVLARSKAPVIASHSGLRHFTPGFERNLSDELAKAVAAKGGVVQVVFGNAFVDPASAADTQAYFVASAKFEEEQAAARKRGETPKSSEAFDKQWEAAHPPRTVKIDAVLDQIDYAVKLLGADHVGIGSDFDGVSGALPEGLKSVADYPNLIDGMKARGHSDETIRKVLGGNLLRVWGEVEAKAVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDR6</accession>
    <name>A0A0S2DDR6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">L-threonine 3-dehydrogenase</fullName>
            <shortName evidence="6">TDH</shortName>
            <ecNumber evidence="6">1.1.1.103</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">tdh</name>
        <name evidence="8" type="ORF">GLE_1319</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-threonine + NAD(+) = (2S)-2-amino-3-oxobutanoate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:13161"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78948"/>
            <dbReference type="EC" id="1.1.1.103"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid degradation; L-threonine degradation via oxydo-reductase pathway; glycine from L-threonine: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.103" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1319"/>
    <dbReference type="EnsemblBacteria" id="ALN56676">
        <property type="protein sequence ID" value="ALN56676"/>
        <property type="gene ID" value="GLE_1319"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1319"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1303"/>
    <dbReference type="OMA" id="GQICDKE"/>
    <dbReference type="UniPathway" id="UPA00046">
        <property type="reaction ID" value="UER00505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008743">
        <property type="term" value="F:L-threonine 3-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019518">
        <property type="term" value="P:L-threonine catabolic process to glycine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00627">
        <property type="entry name" value="Thr_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004627">
        <property type="entry name" value="L-Threonine_3-DHase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00692">
        <property type="entry name" value="tdh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="4 6 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="7">
        <location>
            <begin position="16"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="265"/>
            <end position="267"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="289"/>
            <end position="290"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity for the proton relay mechanism but does not participate directly in the coordination of zinc atom" evidence="6">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN56676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="344" mass="37462" checksum="FA5AB653AFF5F06B" modified="2016-02-17" version="1">MTQTMKALVKREAGKGIWMEQVPVPTPGPNEVLVKLEKTAICGTDLHIYLWDEWSQRTIKPGLVIGHEFVGRVAELGPGVTGYRVGQRVSAEGHIVCGHCRNCRAGRQHLCPNTTGIGVNRDGAFAEYIVMPSSNLWPIPDQIPSELAAFFDPYGNAAHCALEFDVVGEDVLITGAGPIGIIAAGICKHIGARNVVVTDVNDFRLKLAADMGATRVVNVANQSLKDVMADLHMEGFDVGLEMSGNPRAFNDMLDCMYHGGKIAMLGIMPKGAGADWDKIIFKGLTLHGIYGRKMYETWYKMTQLVLSGFPLGKVLTHQLPVDEFQKGFDLMEAGKAGKVVLSWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDS3</accession>
    <name>A0A0S2DDS3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_07290</name>
        <name evidence="2" type="ORF">GLE_1375</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946727.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56732">
        <property type="protein sequence ID" value="ALN56732"/>
        <property type="gene ID" value="GLE_1375"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1375"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1357"/>
    <dbReference type="OMA" id="QVWVVSH"/>
    <dbReference type="OrthoDB" id="318943at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014555">
        <property type="entry name" value="RecF-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029347">
        <property type="entry name" value="RecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_AAA_core" evidence="1">
        <location>
            <begin position="23"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase_AAA_core" evidence="1">
        <location>
            <begin position="248"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="386" mass="42140" checksum="6F1929EE8FC89AEB" modified="2016-02-17" version="1">MLQTLAIAHYRSLHKLELGLGRLNVVTGANGCGKSNLYRALRLLAETAQGGVVPALAREGGLPSALWAGPETVSARMKRGEVAVQGTQRQAPVALRLGFAGEDYGYAIDLGLPIPSRTLFGMDPQIKREAIWSGPFLRSSNLLVDRRGGLARVREGRGWRVAAEHLSSFESLFAQLSDPRAAPEVLTLRETIRGWRFYDHFRSDAQAPARQPQLGTMTPVLSHDGRDLAAAWQTIVEIGDARALAEAVDDAFPGARVRVAGEGGRFVLELEQPGLLRPLSAAELSDGTLRYLLWIAALHTPRPPPLMVLNEPETSLHPDLLPALGRLIARASRRSQVWVVSHATRLVAALEDEDGCNAIRLHKPFGQTEVEGQGLLDAPAWYWPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE11</accession>
    <name>A0A0S2DE11_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase, M16 family</fullName>
            <ecNumber evidence="6">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_1448</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M16 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946781.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1448"/>
    <dbReference type="EnsemblBacteria" id="ALN56805">
        <property type="protein sequence ID" value="ALN56805"/>
        <property type="gene ID" value="GLE_1448"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1448"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1428"/>
    <dbReference type="OMA" id="WAFPAPE"/>
    <dbReference type="OrthoDB" id="1077305at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595383" evidence="3">
        <location>
            <begin position="26"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16" evidence="4">
        <location>
            <begin position="79"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="5">
        <location>
            <begin position="213"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN56805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="474" mass="49654" checksum="DAAB6B01406E3C18" modified="2016-02-17" version="1">MSLLKNPLALSLALILGLGAGAASAGPAAKLPERLPPLAPDKALPVPQIARKTLANGLEVWVVPRQGLPRVDYVLAVRNAGYAADAADASGFASLYAGLLVEGTAKLDAKAIAETAQGYGGAIGANATNDGVVLSGYALPSQAAPMLQLLSDVAEGASFPDDEVKLAQANALQGLKAAQAQPGFKATRALLAAVYGEHPYARSQPTEASINAITADKVRAEHARRFRPDRALLVITGRVGAEQAFKLAEASFGDWKASGEPVADVAPAPRAAPAQRVFVQRDGSVQSALRLGRPAIAATDADYVPAQLAGIVLGGGFSSRLMQNLREDKGYTYGARGGLTALRGGGMVQVSADVRNEVTGASLGEFVYEFGRLNDYPVPAQELEDTKRYVAGGYLIGNQQQRSVASSLAGNWLIGLPPEFLGEYVPKIRAVGADQVQAMAKKYYAVKDQSIVVVGDYKAVQAQLKEYGEFKQEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE37</accession>
    <name>A0A0S2DE37_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Flavodoxin/oxidoreductase NAD-binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_1243</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946622.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1243"/>
    <dbReference type="EnsemblBacteria" id="ALN56600">
        <property type="protein sequence ID" value="ALN56600"/>
        <property type="gene ID" value="GLE_1243"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1243"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1227"/>
    <dbReference type="OMA" id="HEQWEAG"/>
    <dbReference type="OrthoDB" id="707164at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="Flavodoxin-like" evidence="6">
        <location>
            <begin position="92"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="7">
        <location>
            <begin position="245"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN56600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="552" mass="59855" checksum="7BFEA107222B1062" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE66</accession>
    <name>A0A0S2DE66_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Guanyl-specific ribonuclease Sa</fullName>
            <ecNumber evidence="5">3.1.27.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rnaSA</name>
        <name evidence="6" type="ORF">FE772_08145</name>
        <name evidence="5" type="ORF">GLE_1561</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribonuclease N1/T1 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.27.3" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946878.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56918">
        <property type="protein sequence ID" value="ALN56918"/>
        <property type="gene ID" value="GLE_1561"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1561"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1541"/>
    <dbReference type="OMA" id="YANFCTI"/>
    <dbReference type="OrthoDB" id="1989684at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000026">
        <property type="entry name" value="Gua-sp_ribonuclease_N1/T1/U2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016191">
        <property type="entry name" value="Ribonuclease/ribotoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00545">
        <property type="entry name" value="Ribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53933">
        <property type="entry name" value="SSF53933"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242181" evidence="4">
        <location>
            <begin position="23"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW25643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="127" mass="13670" checksum="62730ACD8C24282A" modified="2016-02-17" version="1">MNHVDRAAFVLGLCLLAGAAAAAAPKACTSLPPDIKEAMRTMSFCITATDPVAECGRNGMDVQIFSNNEGKLPNAGRGQVYWEGKIRQNTGAAGQRRLVYLVTDGTKKVVAARYYTPDHYANFCTIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DED3</accession>
    <name>A0A0S2DED3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_21620</name>
        <name evidence="5" type="ORF">FE772_07760</name>
        <name evidence="3" type="ORF">GLE_1478</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 8">YC36</strain>
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    </evidence>
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</entry>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
    <sequence length="253" mass="27144" checksum="2F410D3BB3046CBD" modified="2016-02-17" version="1">MDIREHDIDREPPGADVQAGEYVLGVLDERERRLAELRVETDPAFARLVGDWQRRLAALIEEIEPVAAPAQLWPRLRVRLGWSPVQGERPRGLWHSAGFWRGAAAAAAALAVVAWWSGRAPTPAPVAPPLADKPPLMIEHQPAFPVTRLARDDGSAGWLASIDLRHAKVMTMAVPTPEDPQGRVAELWLIPKGEAPRSLGLISTEWADSLKVSPEALSKLAAGATLAITLEPPGGAPHGVPTGPIVAKGNIAL</sequence>
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<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF00</accession>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <source>
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    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
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    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
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        </source>
    </evidence>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
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            <end position="1376"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1410" mass="136427" checksum="3485ED6518AF742E" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF42</accession>
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        <submittedName>
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        </submittedName>
    </protein>
    <gene>
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    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="ALN57040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW25739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1684"/>
    <dbReference type="EnsemblBacteria" id="ALN57040">
        <property type="protein sequence ID" value="ALN57040"/>
        <property type="gene ID" value="GLE_1684"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1684"/>
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    <dbReference type="OMA" id="EAQYWFW"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
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        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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            <begin position="188"/>
            <end position="207"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="8">
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="266"/>
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        <location>
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            <end position="338"/>
        </location>
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            <begin position="47"/>
            <end position="205"/>
        </location>
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        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN57040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW25739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="614" mass="67031" checksum="ABF703E38EAC5D5E" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF75</accession>
    <name>A0A0S2DF75_LYSEN</name>
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        <submittedName>
            <fullName evidence="4">DNA polymerase III subunit delta prime</fullName>
            <ecNumber evidence="4">2.7.7.7</ecNumber>
        </submittedName>
    </protein>
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        <name evidence="4" type="primary">holB</name>
        <name evidence="4" type="ORF">GLE_1698</name>
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    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.7" evidence="4"/>
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        <property type="protein sequence ID" value="ALN57054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN57054">
        <property type="protein sequence ID" value="ALN57054"/>
        <property type="gene ID" value="GLE_1698"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1698"/>
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    <dbReference type="OrthoDB" id="1971388at2"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0008408">
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        <property type="project" value="InterPro"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="323" mass="35187" checksum="3A36422E8DA73C41" modified="2016-02-17" version="1">MSAVFAPWQRRIYDQAQASIAAGRLGHGLLFCGPAELGKRAVAQRLAEGLLCRERLSDGGPCGRCRSCLLLAAGTHPDYQLVSFVPNKEGTKLRTEIVIEQIRNLSERLALTPQYGGAQIAIIDPADAINTAACNALLKTLEEPVPGRYLWLVSSHPARLPATIRSRCQRLEFRLPPRDEALAWLKAQGHADAAAREAFDAARGHPGLAHEWLTGDGLKLRREVAADLAKLGRGETSAPEVAQRWVGDEHAVLRLRHASDIALAEASAGLTDPARARSLASWFDRANRTRELLRTTVRADLAVTELLMAWRSDEARRAGGGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-06-17" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF85</accession>
    <name>A0A0S2DF85_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HTH type transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">XRE family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_08520</name>
        <name evidence="2" type="ORF">GLE_1643</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946939.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57000">
        <property type="protein sequence ID" value="ALN57000"/>
        <property type="gene ID" value="GLE_1643"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1643"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1622"/>
    <dbReference type="OMA" id="MEASDGN"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="7"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="84" mass="8794" checksum="7186A728E44C5C82" modified="2016-02-17" version="1">MITASQLRAARALVGMDQKTLAEKAGVSLPTIQRMEASQGNVRGVVDTLTKIISALDAAGVELIGENMPSYGTGRGVRLKSPPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFH3</accession>
    <name>A0A0S2DFH3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histidine biosynthesis bifunctional protein HisB</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="10">Histidinol-phosphatase</fullName>
                <ecNumber evidence="10">3.1.3.15</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="10">Imidazoleglycerol-phosphate dehydratase</fullName>
                <shortName evidence="10">IGPD</shortName>
                <ecNumber evidence="10">4.2.1.19</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="10 11" type="primary">hisB</name>
        <name evidence="12" type="ORF">BV903_17300</name>
        <name evidence="13" type="ORF">FE772_09710</name>
        <name evidence="11" type="ORF">GLE_1900</name>
    </gene>
    <organism evidence="11 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">C3</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">B25</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:11040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="EC" id="4.2.1.19"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>H2O + L-histidinol phosphate = L-histidinol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14465"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="3.1.3.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 6/9.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 8/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">In the N-terminal section; belongs to the histidinol-phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.15" evidence="10"/>
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        <property type="gene ID" value="BV903_17300"/>
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    </dbReference>
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    </dbReference>
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            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Imidazoleglycerol-phosphate dehydratase" evidence="10">
        <location>
            <begin position="172"/>
            <end position="377"/>
        </location>
    </feature>
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        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="13"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
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        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
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    </evidence>
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        <source>
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        </source>
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        <source>
            <dbReference type="EMBL" id="ALN57251.1"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="OPD62688.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="377" mass="41570" checksum="B2F2BBD15D231D48" modified="2016-02-17" version="1">MSALKPVLFVDRDGTLIEEPADFQIDSYAKLRFVRGVIPALLKLRDAGYEFVMVTNQDGLGTESFPRWAFDGPHQLMMQVFESQGIAFRDVLIDTSFAAENLPTRKPGIGLALPLLKDRGIDWERSAMVGDRETDNGFAANLGIRAFQLRTAEFGGEWDWAGIAHVLADRPRTARVARNTKETRIEVKVDLDRAAEPKVATGLGFFDHMLEQLGKHGGFALELRCEGDLHIDEHHTIEDSALALGQALREALGDKRGIGRYGFEPRAAGGDGSAPPAHEFVLPMDETLARAALDFSGRPYFVFAGSFARDRVGDFPTELLAHFFRSLCETAGLNLNLNVEGDNDHHKIEACFKAVARALRQAIARQGRELPSTKGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFP3</accession>
    <name>A0A0S2DFP3_LYSEN</name>
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        <recommendedName>
            <fullName evidence="1">zf-CGNR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2004</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
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            <taxon>Bacteria</taxon>
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            <taxon>Xanthomonadaceae</taxon>
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        </lineage>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ABATE"/>
    </dbReference>
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        <property type="entry name" value="ABATE_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Znf_CGNR"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="zf-CGNR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF160904"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-CGNR" evidence="1">
        <location>
            <begin position="143"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="187" mass="20293" checksum="6F797EE728A7D1B6" modified="2016-02-17" version="1">MTTPTPTDWPPLIAGQPALDLLNTLTLEGGALVEHLTDDAAAAAWLSRASGHAQAPQPHLAERARALREAIRAAVEARKQGRPVALAPLNALLAHMHSHWVLEPGEDGAAARRAAVGDPAWRALAPLGEAAAQLLAELDFALVRQCEHSDCVLWFHDTTKSHRRRWCAMALCGNRHKVSEFRKRRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG49</accession>
    <name>A0A0S2DG49_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57481">
        <property type="protein sequence ID" value="ALN57481"/>
        <property type="gene ID" value="GLE_2131"/>
    </dbReference>
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    <dbReference type="PATRIC" id="fig|69.6.peg.2095"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="62" mass="6604" checksum="1BC5F74DB10440BB" modified="2016-02-17" version="1">MGLRSKRKGNGSINGNGNGNGNGNGNGNGCDEMDSALTATTGKGRRRRREARWPGFRRRKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG72</accession>
    <name>A0A0S2DG72_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Winged helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_10720</name>
        <name evidence="3" type="ORF">GLE_2122</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57472">
        <property type="protein sequence ID" value="ALN57472"/>
        <property type="gene ID" value="GLE_2122"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2122"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2086"/>
    <dbReference type="OMA" id="QIWRGRI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
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        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
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        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="139" mass="15733" checksum="018C8522FA5AF9B6" modified="2016-02-17" version="1">MVEHNSQRLDAVFQALADPTRRAMLRQLADGERKVGELAEPYAMTLAAASKHIKALERAGLVRREVRGRIHVCRLDAQPLHGGFEWLRHYERFWNQRLDDLEALLRAEDDASRRAPAPAAPTSAASAEPPRPSRRKPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG82</accession>
    <name>A0A0S2DG82_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FE772_11205</name>
        <name evidence="13" type="ORF">GLE_2223</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">C3</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2223"/>
    <dbReference type="EnsemblBacteria" id="ALN57572">
        <property type="protein sequence ID" value="ALN57572"/>
        <property type="gene ID" value="GLE_2223"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2223"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2188"/>
    <dbReference type="OMA" id="PEQWRRY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009736">
        <property type="term" value="P:cytokinin-activated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006189">
        <property type="entry name" value="CHASE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042240">
        <property type="entry name" value="CHASE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03924">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM01079">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50839">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0932">Cytokinin signaling pathway</keyword>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="CHASE" evidence="12">
        <location>
            <begin position="165"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="11">
        <location>
            <begin position="379"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="10">
        <location>
            <begin position="532"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN57572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW26152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="750" mass="83340" checksum="FF254A72A8E381AD" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG88</accession>
    <name>A0A0S2DG88_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">4-hydroxy-tetrahydrodipicolinate reductase</fullName>
            <shortName evidence="9">HTPA reductase</shortName>
            <ecNumber evidence="9">1.17.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 12" type="primary">dapB</name>
        <name evidence="13" type="ORF">BV903_23105</name>
        <name evidence="14" type="ORF">FE772_11270</name>
        <name evidence="12" type="ORF">GLE_2236</name>
    </gene>
    <organism evidence="12 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">C3</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">B25</strain>
        </source>
    </reference>
    <reference evidence="14 17" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(S)-2,3,4,5-tetrahydrodipicolinate + H2O + NAD(+) = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:35323"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="EC" id="1.17.1.8"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(S)-2,3,4,5-tetrahydrodipicolinate + H2O + NADP(+) = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:35331"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="EC" id="1.17.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the DapB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.</text>
    </comment>
    <dbReference type="EC" id="1.17.1.8" evidence="9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000078">
        <property type="protein sequence ID" value="OPD61553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947388.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000078.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2236"/>
    <dbReference type="EnsemblBacteria" id="ALN57585">
        <property type="protein sequence ID" value="ALN57585"/>
        <property type="gene ID" value="GLE_2236"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61553">
        <property type="protein sequence ID" value="OPD61553"/>
        <property type="gene ID" value="BV903_23105"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2236"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2201"/>
    <dbReference type="OMA" id="ALKACEY"/>
    <dbReference type="OrthoDB" id="803114at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00018"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008839">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate reductase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="term" value="F:NADP binding"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="F:oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="match status" value="1"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01113">
        <property type="entry name" value="DapB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01298">
        <property type="entry name" value="DAPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
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    <keyword evidence="8 9" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0520">NAD</keyword>
    <keyword evidence="4 9" id="KW-0521">NADP</keyword>
    <keyword evidence="6 9 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DapB_N" evidence="10">
        <location>
            <begin position="9"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="DapB_C" evidence="11">
        <location>
            <begin position="126"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="(S)-2,3,4,5-tetrahydrodipicolinate binding" evidence="9">
        <location>
            <begin position="162"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
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            <position position="152"/>
        </location>
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        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="15"/>
            <end position="20"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
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    <feature type="binding site" evidence="9">
        <location>
            <position position="42"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
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        <location>
            <begin position="96"/>
            <end position="98"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="120"/>
            <end position="123"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
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        <location>
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        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:16845"/>
        </ligand>
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            <dbReference type="ARBA" id="ARBA00006642"/>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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        <source>
            <dbReference type="Pfam" id="PF01113"/>
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        <source>
            <dbReference type="Pfam" id="PF05173"/>
        </source>
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    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN57585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OPD61553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW26164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="245" mass="25523" checksum="C7AD6C63CD14844E" modified="2016-02-17" version="1">MNDTAKTPIRLLIHGASGRMGQALLRLARERDDLVVVAAYSRSQPSQRVIDGVPHFAAAELGGAPEFDVAVDFSLPDGFDPVLALCAARGKALVSGTTGLSSAQNAAINDAAAGIGVVWAANYSLGVAVLTELVRRAAAALPGWDCDVVEAHHTRKLDAPSGTALHLGAAVAIGRGSEPHYASLRAGDIVGEHTVQFAAPGERLELIHRASNRDIFARGALEAAVRVAQQAPGRYGLAELMFPNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGC2</accession>
    <name>A0A0S2DGC2_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">RES domain superfamily</fullName>
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        <submittedName>
            <fullName evidence="5">RES domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_20110</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MbcT/ParT/Res family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="GLE_2212"/>
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        <property type="gene ID" value="BV903_20110"/>
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    <dbReference type="OrthoDB" id="1821714at2"/>
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    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="18"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD62136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26142.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="159" mass="17165" checksum="A8110964023F96A3" modified="2016-02-17" version="1">MTKLWRIAGETRAYRADDLSGAGAAKFPGRWNDEGQRVLYSATSLALAALETAAYVDAHGLPLNRHVVSIEVPPAVWKARIQMTAADLPGGWDAVPAGMASVGIGSRWLQSGASAILLVPSVIVPEEYNALINPEHRDAKKLRATTGRKFQYNVVFRAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGE1</accession>
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        <recommendedName>
            <fullName evidence="2">PBP_domain domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2338</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947463.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2338"/>
    <dbReference type="EnsemblBacteria" id="ALN57687">
        <property type="protein sequence ID" value="ALN57687"/>
        <property type="gene ID" value="GLE_2338"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2338"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2300"/>
    <dbReference type="OMA" id="IFANGAC"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595528" description="PBP_domain domain-containing protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="2">
        <location>
            <begin position="84"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="447" mass="45336" checksum="66500268E8E8CEF1" modified="2016-02-17" version="1">MHRNKLHVGLLAATAVLVFAGSANAADLYGGGATFPAPAYVGDLYNGTSPVAKLSRDSAITLPAVTFSVAGLGNSTGTKVPVFKDFHTRYSADAVSYCQTGSGTGKKILNNDGIFANGACSPAGITGFSSVSGQSAPDFIGTDAPIATADYNTFITNMASTRTAIVQIPVLAGAIALPFKDTVGGLTSVALNTEQVCRIFAGDIKNWNDSRLASPVAGSHPITIVYRSEGSGTSFAFTSYLAAQCNGKFGLATDFFKPNQSFATAAALALPNYSASSAQAGNNGVVSKVKTTTDAIGYADIAEVLSQGVMYASVNGNDPALFGSTGAVSLAPAALLSGKVLDGATVADVPASVAAPARNCTRLVNPTAVISGAYPIAAVTYLAAYNAGNGTKATPLKNLFKQFYAPLPVGGVTPPDTRVALPTGYAYIDGNALFRSSAVGSINSCIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGG3</accession>
    <name>A0A0S2DGG3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycogen-debranching protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Isoamylase</fullName>
            <ecNumber evidence="3">3.2.1.68</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">iam</name>
        <name evidence="4" type="ORF">FE772_11865</name>
        <name evidence="3" type="ORF">GLE_2370</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.68" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947487.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2370"/>
    <dbReference type="EnsemblBacteria" id="ALN57719">
        <property type="protein sequence ID" value="ALN57719"/>
        <property type="gene ID" value="GLE_2370"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2370"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2331"/>
    <dbReference type="OMA" id="VAYNGWS"/>
    <dbReference type="OrthoDB" id="99080at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004133">
        <property type="term" value="F:glycogen debranching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019156">
        <property type="term" value="F:isoamylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02856">
        <property type="entry name" value="E_set_GDE_Isoamylase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044505">
        <property type="entry name" value="GlgX_Isoamylase_N_E_set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726803" evidence="1">
        <location>
            <begin position="34"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="domain" description="Aamy" evidence="2">
        <location>
            <begin position="218"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="778" mass="84355" checksum="C15D7DA59F0DF147" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGH8</accession>
    <name>A0A0S2DGH8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Outer-membrane lipoprotein carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 10" type="primary">lolA</name>
        <name evidence="11" type="ORF">BV903_01935</name>
        <name evidence="12" type="ORF">FE772_11640</name>
        <name evidence="10" type="ORF">GLE_2320</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">C3</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the LolA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000004">
        <property type="protein sequence ID" value="OPD65553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947448.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2320"/>
    <dbReference type="EnsemblBacteria" id="ALN57669">
        <property type="protein sequence ID" value="ALN57669"/>
        <property type="gene ID" value="GLE_2320"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65553">
        <property type="protein sequence ID" value="OPD65553"/>
        <property type="gene ID" value="BV903_01935"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2320"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2285"/>
    <dbReference type="OMA" id="YDPFVEQ"/>
    <dbReference type="OrthoDB" id="1933827at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044874">
        <property type="term" value="P:lipoprotein localization to outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042953">
        <property type="term" value="P:lipoprotein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16325">
        <property type="entry name" value="LolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00240">
        <property type="entry name" value="LolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029046">
        <property type="entry name" value="LolA/LolB/LppX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004564">
        <property type="entry name" value="OM_lipoprot_carrier_LolA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018323">
        <property type="entry name" value="OM_lipoprot_carrier_LolA_Pbac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35869">
        <property type="entry name" value="PTHR35869"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03548">
        <property type="entry name" value="LolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89392">
        <property type="entry name" value="SSF89392"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00547">
        <property type="entry name" value="lolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7 9" id="KW-0574">Periplasm</keyword>
    <keyword evidence="8 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0732">Signal</keyword>
    <keyword evidence="5 9" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008995357" description="Outer-membrane lipoprotein carrier protein" evidence="9">
        <location>
            <begin position="23"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN57669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OPD65553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW26225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="212" mass="22644" checksum="A55240EBB315487C" modified="2016-02-17" version="1" precursor="true">MTRFVRQAALALSLSATLFAGAAVAGARDDLNAFTRGLKGLDGQFAQQVYDPNGKLKESSTGQVALSAPRLFRWEYAKPYPQLIVADGKKVWVYEPDLQQVSVRPQGAEEQNSPLAALIDPSKLDAMFAVKELGGGDGGLSWLLLTPKSQGEASFRSARLGFSGGTLSKMEIVDALGQKTEISFSGWKRNPSFPASTFKYAPGKGVDVIGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGJ4</accession>
    <name>A0A0S2DGJ4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2402</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57751">
        <property type="protein sequence ID" value="ALN57751"/>
        <property type="gene ID" value="GLE_2402"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2402"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2364"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="40" mass="4290" checksum="CA7EE70D70EDC0AB" modified="2016-02-17" version="1">MPAPRGIRGSPAACVPHRRFDRFAQRTGSPHGLCPTPPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGU8</accession>
    <name>A0A0S2DGU8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Two-component system response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_2281</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2017-10" db="EMBL/GenBank/DDBJ databases">
            <title>Cyclic di-GMP signaling enzymes in Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Xu G."/>
                <person name="Qian G."/>
                <person name="Liu F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">OH11</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MG387215">
        <property type="protein sequence ID" value="ATU81874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2281"/>
    <dbReference type="EnsemblBacteria" id="ALN57630">
        <property type="protein sequence ID" value="ALN57630"/>
        <property type="gene ID" value="GLE_2281"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2281"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2246"/>
    <dbReference type="OMA" id="RCANTQF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="HD-GYP" evidence="4">
        <location>
            <begin position="133"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="HD" evidence="3">
        <location>
            <begin position="155"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ATU81874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="338" mass="38273" checksum="F1870ED540F12D3F" modified="2016-02-17" version="1">MLRHIIEDIASELQVHDFGEPEAALAWCESHQPDLLLLDYRMPGIDGLEFARRFRRLPMHRDIPIILVTVVGDEPVRQAALEAGVIDFLVKPVRPRELRARCRNLLALRQQSENVKQRALSLEQRLLSSMHEVEERERETLSRLARAIEFRDAGTSAYLERMAHIAGLIAEQLGMFEDEIRVIEMAAPLHDIGKIAIPDAVLMKPGPLTEEETAIMRRHPKIGYELLSGSQNRFIQAGALIALRHHERYDGSGYPDGLVGEEIPLEARIVAVADVFDALISPRPYKKAWDVDAALGYLYAQRGRLFDPRCVDALIRSRTRLDELCARFSTVPSRPGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGX0</accession>
    <name>A0A0S2DGX0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Phosphatase NudJ</fullName>
            <ecNumber evidence="5">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nudJ</name>
        <name evidence="7" type="ORF">GLE_2302</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2 5">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the Nudix hydrolase family. NudJ subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2302"/>
    <dbReference type="EnsemblBacteria" id="ALN57651">
        <property type="protein sequence ID" value="ALN57651"/>
        <property type="gene ID" value="GLE_2302"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2302"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2267"/>
    <dbReference type="OMA" id="QPAGHLD"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017110">
        <property type="term" value="F:nucleoside-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:nucleoside-triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004787">
        <property type="term" value="F:thiamine-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03675">
        <property type="entry name" value="Nudix_Hydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033713">
        <property type="entry name" value="NudJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="6">
        <location>
            <begin position="8"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="165" mass="18261" checksum="D7315F98B56821B2" modified="2016-02-17" version="1">MSYREGRFWQPDVTVATVVVDGGRLLMVEETVGGRLVLNQPAGHLEPDESLLEAALRETLEETGWQVRLTAFVGAYQWKAPDASAGGSGRHYLRFAFAAEPVRHDPRRPLDEGIVQALWLTPAELQARAGDHRSPLVWQVAADYLGGRRHSLDLVQHFADAAAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHC0</accession>
    <name>A0A0S2DHC0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glutamate dehydrogenase</fullName>
            <ecNumber evidence="2">1.4.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_2691</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15133"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.4.1.2"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="1.4.1.2" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947739.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2691"/>
    <dbReference type="EnsemblBacteria" id="ALN58039">
        <property type="protein sequence ID" value="ALN58039"/>
        <property type="gene ID" value="GLE_2691"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2691"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2650"/>
    <dbReference type="OMA" id="RATRWFL"/>
    <dbReference type="OrthoDB" id="79339at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004352">
        <property type="term" value="F:glutamate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019551">
        <property type="term" value="P:glutamate catabolic process to 2-oxoglutarate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028971">
        <property type="entry name" value="NAD-GDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007780">
        <property type="entry name" value="NAD_Glu_DH_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024727">
        <property type="entry name" value="NAD_Glu_DH_bac_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43403">
        <property type="entry name" value="PTHR43403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05088">
        <property type="entry name" value="Bac_GDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12466">
        <property type="entry name" value="GDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036761">
        <property type="entry name" value="GDH_Mll4104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GDH_N" evidence="5">
        <location>
            <begin position="50"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1703" mass="187810" checksum="09E7CA719B9916AA" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHG5</accession>
    <name>A0A0S2DHG5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Amidohydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Amidohydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_01600</name>
        <name evidence="5" type="ORF">FE772_12615</name>
        <name evidence="3" type="ORF">GLE_2510</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000003">
        <property type="protein sequence ID" value="OPD65716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947595.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2510"/>
    <dbReference type="EnsemblBacteria" id="ALN57859">
        <property type="protein sequence ID" value="ALN57859"/>
        <property type="gene ID" value="GLE_2510"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65716">
        <property type="protein sequence ID" value="OPD65716"/>
        <property type="gene ID" value="BV903_01600"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2510"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2473"/>
    <dbReference type="OMA" id="SSDCHAG"/>
    <dbReference type="OrthoDB" id="1832218at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="PTHR21240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="89"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD65716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="451" mass="50829" checksum="2B2C2C9795195398" modified="2016-02-17" version="1">MKPYTLISVDGHAGLPTAQYRDYLERKHHAAFDEELEQLALLRKGFLTAGKNAKQTPLMYQAHMHRYSDPGNGEMQERIRGAWDLDVRLKELDAEGVIGEVLFPDGQGFNSFPFGGFFGEHPVPIRDPELRAAGARAHNRWLAEFCAASGGRLQGVAMIMPFDIWQAVADVRWAYAAGLRGIVLPPPDETYPPYHEAVFDPLWAVCAELGMAVHSHGGDPPKIYGQNIASQTLAILELGFFRRRILAQLMFGGVFVRHPNLRFVYTEVGIDWLPNFIELLEHVYHNDWLRMGRAPKQWLSLSPKDAWARNCAAAATAATFDEIQQARRLGFDTVMWGADYPHVEGGWPHSWDEIRQAFATVGDDDRRKMVGENAARFYRFDPQLIESLVAKIGPPAGTFVSDEAPQRPEFSVHDFTNGWVNTYGGFARNMRWSLDSPDTHPDSRPNAKRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHJ5</accession>
    <name>A0A0S2DHJ5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_12560</name>
        <name evidence="1" type="ORF">GLE_2499</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947585.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2499"/>
    <dbReference type="EnsemblBacteria" id="ALN57848">
        <property type="protein sequence ID" value="ALN57848"/>
        <property type="gene ID" value="GLE_2499"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2499"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2462"/>
    <dbReference type="OrthoDB" id="942099at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021466">
        <property type="entry name" value="Put_rhamnosyl_transferase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11316">
        <property type="entry name" value="Rhamno_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="373" mass="42739" checksum="346132B926587BD8" modified="2016-02-17" version="1">MLWHAVITRFSYRHTTSAAGLNGVLVSLLRRDPLEPKRLALRYSLFELTCLPSLLGQTSQDFDWFIVVDRDLPPSWRERLQALVAGRPRTHLYDYDPAQDLTETGWLQPYAPAHTTRLLTTILDDDDALPADFVEQMQRTVAQREAELAPIATLASRKSRQWELVHSRRAPLGYRCAWHRGDWVLSTGLSLLCRWPQHRLTVLAIHHQVADLWFLPERGPALMQLLQQRWSLNDARAVEATAFIAGRMDDFQQRAQACVDGEAGADAADAAGEGALRFVDLSDTVEAFVVSNHFGNDQVLRLFEPKPDREPVSGPQDFPGVPIDFARFRGNARAFGKRPRVYRELVRELWSRPMPWWPRLRMVAWASWRFARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHT1</accession>
    <name>A0A0S2DHT1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947707.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2655"/>
    <dbReference type="EnsemblBacteria" id="ALN58003">
        <property type="protein sequence ID" value="ALN58003"/>
        <property type="gene ID" value="GLE_2655"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2655"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2614"/>
    <dbReference type="OMA" id="GCFDWHS"/>
    <dbReference type="OrthoDB" id="1361366at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021365">
        <property type="entry name" value="DUF2891"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11199">
        <property type="entry name" value="DUF2891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594806" evidence="1">
        <location>
            <begin position="29"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="388" mass="42054" checksum="D5FBFD92A74F5613" modified="2016-02-17" version="1">MGKGRNGRRRAGAGWGLAALLAAGQAVATPAPPPPRLDAVQAANFAALALDCVDREYPNKIAHRLDGAADARAPSQLYPAFYGCYDWHSAVHGHWLLARLAQRFPGEPFAPRARQALDRHLTAANIAGELAYLRRNDDESFERPYGLAWLLQLGAQLRGWDDPQARRWAQALEPLEREAAARLQRWLPKLTRPIRVGEHSQTAFAFGLALDWTQVSGDRALRQALLARSRDYYLGDRDCPLAYEPSGQDFLSPCLAEADLMRRVLAPAEFAAWLDRFLPAIPRRARADWLAPGVVLDKADGKLAHLDGLNLSRAWMLEGIAAGLPPRDRRVPALRAAAARHRELGLAAVSGGHYAGAHWLGSFATYLLAPPGAAGEGAAPAAAAAGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHY5</accession>
    <name>A0A0S2DHY5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Dihydrolipoyl dehydrogenase</fullName>
            <ecNumber evidence="3 13">1.8.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">lpdA</name>
        <name evidence="17" type="ORF">FE772_13640</name>
        <name evidence="16" type="ORF">GLE_2725</name>
    </gene>
    <organism evidence="16 18">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="16 18" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">C3</strain>
        </source>
    </reference>
    <reference evidence="17 19" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NAD(+) = (R)-N(6)-lipoyl-L-lysyl-[protein] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:15045"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="1.8.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="11 13">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="13">The active site is a redox-active disulfide bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.4" evidence="3 13"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947768.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2725"/>
    <dbReference type="EnsemblBacteria" id="ALN58073">
        <property type="protein sequence ID" value="ALN58073"/>
        <property type="gene ID" value="GLE_2725"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2725"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2683"/>
    <dbReference type="OMA" id="DAKYGEW"/>
    <dbReference type="OrthoDB" id="267896at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006258">
        <property type="entry name" value="Lipoamide_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01350">
        <property type="entry name" value="lipoamide_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 11 13" id="KW-0274">FAD</keyword>
    <keyword evidence="4 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 11 13" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 13 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 13" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="15">
        <location>
            <begin position="5"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="14">
        <location>
            <begin position="353"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="451"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="188"/>
            <end position="195"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="325"/>
            <end position="328"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="12">
        <location>
            <begin position="49"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ALN58073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="QCW26549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="474" mass="50003" checksum="D3682E22445E11B6" modified="2016-02-17" version="1">MSEQFDVVVIGAGPAGYHAAIRAAQLGLKTACIDAALGKDGKPALGGTCLRVGCIPSKALLDSSRQYWNLQHLFGEHGISADNAKIDVGTMVGRKDKIVKQFTGGIAMLFKANKITPYYGFGTLHPGNIVKVKQHDGSEVELKGTNVIIAAGSDSIELPFAKFDGDKIVDNVGALDFTAVPKRLGVIGAGVIGLELGSVWKRLGSEVTILEAMPDFLAAADAEVAKTAAKEFKKQGLDIKLGAKVSKAEIKGDEVHLTYNDGKADQQLVVDKLLVAVGRRAASKGLLADGTGVKLNERGQIEVDEHCHTGVDGVWAVGDCVRGPMLAHKGFEEGIAVAELIAGLPGHVNFDTIPWVIYTEPEIAWVGQTEQQLKADGVPYKTGSFPFAAIGRAVAMGEPAGFVKVIAHAETDRVLGLHLVGVGVSELVHEGVLTMEFKGSADDLARICHAHPTLSEAIHDAAMAVDKRAIHKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI46</accession>
    <name>A0A0S2DI46_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_14340</name>
        <name evidence="2" type="ORF">GLE_2872</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947876.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58220">
        <property type="protein sequence ID" value="ALN58220"/>
        <property type="gene ID" value="GLE_2872"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2872"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2834"/>
    <dbReference type="OMA" id="DEMTQEC"/>
    <dbReference type="OrthoDB" id="1936380at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726662" evidence="1">
        <location>
            <begin position="30"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="249" mass="26154" checksum="32327858AE1E3F53" modified="2016-02-17" version="1">MPTPSLRNALLAALLIPAALAPAFVPAHAAKPSKSKAAKAAKAAAPKNTLKPEQVAELYARIALRQDAEAATQLNDYLKPLFPNGEKAVVLADQAAMDAQYDGFADAMLEDMPKVDKKKAKPAVAAAIKRVNLLASGAECRGVSNREYANEYVKNGRIAEVEMQCTVPVLGARLQEVLAGKGAPAKLKTKKLLEGVAEFDRALGQAGSRTIPAKLTLYASAKGQPWNTGGADDIVETVHNGMYGPAAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI88</accession>
    <name>A0A0S2DI88_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2902</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58250">
        <property type="protein sequence ID" value="ALN58250"/>
        <property type="gene ID" value="GLE_2902"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2902"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2864"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="39" mass="4255" checksum="9B5EA07B7A00688E" modified="2016-02-17" version="1">MLSDPIAASRHAFAAESLWGGFSPEALRSDRRDPARVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI94</accession>
    <name>A0A0S2DI94_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_15070</name>
        <name evidence="1" type="ORF">GLE_3015</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947982.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3015"/>
    <dbReference type="EnsemblBacteria" id="ALN58363">
        <property type="protein sequence ID" value="ALN58363"/>
        <property type="gene ID" value="GLE_3015"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3015"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2976"/>
    <dbReference type="OMA" id="DRTWQQL"/>
    <dbReference type="OrthoDB" id="629908at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="375" mass="40934" checksum="BFB9F99ABA047975" modified="2016-02-17" version="1">MRKILGPAIAAVLLLGVVAGIVMSFNGKRADDRAAAETRKQQADAAARVNVRVLTGSEKLEFLRDPELAQVLLADNIVLDVQKAGSREIATRPDLKSFDAAYPAGTAAARKIADATGSRRIYNGFYTPMTVASWKPLLPTLEANGIVGKRGDAYFIVDMRKLVALMEGGARWKDLQPNPNYAVGKSVLITSTDVRTSNSAAMYLALASYLANGDDVVASETAADQVADRLVHLFSKQGYQESSSSGPFEDYVTMKMGKSPLVMIYEQQFLEYAFKHPRVDPDMVLLYPQPTVLTKHTLVALNDKGARFAEAFERNPKVRAIAARYGLRGPDNAALFADAGKRGIDMPQQLVDVVDPPTYDLLERMIGRIESRLGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIB5</accession>
    <name>A0A0S2DIB5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Outer membrane protein assembly factor BamB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">yfgL</name>
        <name evidence="4" type="synonym">bamB</name>
        <name evidence="5" type="ORF">GLE_2906</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the Bam complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the BamB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2906"/>
    <dbReference type="EnsemblBacteria" id="ALN58254">
        <property type="protein sequence ID" value="ALN58254"/>
        <property type="gene ID" value="GLE_2906"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2906"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2868"/>
    <dbReference type="OMA" id="GRVLWQR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051205">
        <property type="term" value="P:protein insertion into membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00923">
        <property type="entry name" value="OM_assembly_BamB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017687">
        <property type="entry name" value="BamB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03300">
        <property type="entry name" value="assembly_YfgL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="402" mass="42208" checksum="87850ED88687C996" modified="2016-02-17" version="1">MRVAATAALFAFALSGCSTVKGWFGGSKKKDDGKPNEPTELVDFTASVKVDKIWSVNAGKGEDRIGVRQAPAVADGRVYAAAIKGGVHAYDLQTGKEVWHFVPTRKDKKDREKKDKEIRLSGGPGAGDGLVVVGGLDGEVIALDAATGAQKWTASVPNEVIAAPTIGLGMVFVRSNDGRVTAFDAASGERRWFWNRDVPILSLRGNSAPTLGPGYVFVGNDDGTLSALAASDGRSTWDVPVAQPDGRSELDRMADIDGAPVLEGTVLYATSFKKQTMAIDAPSGRPMWASEHGGAGRLGVASDKLIVADPAGTVFGLDKTSGAALWSQPSLARRDLTGAAVQGDYALVGDFDGYVHWMKLSTGEFAARARAGRKPLKAAPVVVDGIAIVQNIKGELTAFKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIJ2</accession>
    <name>A0A0S2DIJ2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2956</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58304">
        <property type="protein sequence ID" value="ALN58304"/>
        <property type="gene ID" value="GLE_2956"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2956"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="38" mass="4226" checksum="64B4D71F5D80CBA3" modified="2016-02-17" version="1">MERRHERKGLRDHRRARARAGARVAGRRTAGNVAAGDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIM9</accession>
    <name>A0A0S2DIM9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_2957</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947937.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2957"/>
    <dbReference type="EnsemblBacteria" id="ALN58305">
        <property type="protein sequence ID" value="ALN58305"/>
        <property type="gene ID" value="GLE_2957"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2957"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2918"/>
    <dbReference type="OMA" id="CQFEYST"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd05235">
        <property type="entry name" value="SDR_e1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013120">
        <property type="entry name" value="Far_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010080">
        <property type="entry name" value="Thioester_reductase-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01746">
        <property type="entry name" value="Thioester-redct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 5" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="534"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="1637"/>
            <end position="1712"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="2734"/>
            <end position="2809"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1715"/>
            <end position="1742"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="5">
        <location>
            <position position="569"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="5">
        <location>
            <position position="1672"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="5">
        <location>
            <position position="2769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="3204" mass="345598" checksum="14FF625A3781B443" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJL9</accession>
    <name>A0A0S2DJL9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zinc metalloprotease</fullName>
            <ecNumber evidence="9">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rseP</name>
        <name evidence="12" type="ORF">FE772_16670</name>
        <name evidence="11" type="ORF">GLE_3378</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the peptidase M50B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948252.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3378"/>
    <dbReference type="EnsemblBacteria" id="ALN58724">
        <property type="protein sequence ID" value="ALN58724"/>
        <property type="gene ID" value="GLE_3378"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3378"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3328"/>
    <dbReference type="OMA" id="QYMVGFG"/>
    <dbReference type="OrthoDB" id="1395197at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004387">
        <property type="entry name" value="Pept_M50_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42837">
        <property type="entry name" value="PTHR42837"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00054">
        <property type="entry name" value="TIGR00054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="11" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="378"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="423"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="10">
        <location>
            <begin position="115"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="10">
        <location>
            <begin position="204"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN58724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW27031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="453" mass="49169" checksum="E50D89A2BAA5A4B3" modified="2016-02-17" version="1">MSEILGSLWWLIISIGLLVTFHEFGHFWVARRCGVKVLRFSIGFGKPLWMRVGKDGTEYAIGRIPLGGYVKMLDEREYEIGEALKPHAFNRKPVWQRIAIVFAGPAANLILCVAFLWGMFVIGRPDFAPVVGSSAGIAAEAGLRRGDTVEAIGERATPTWSEVQMALIPHALDREDVAVKVRAQNGSQQTRTLRLSQLPAGFDERRVVQVIGLGGRHELIPALVGRVEPDSAAWRVLAEGDRITALDGDPIASWNDLPAAVAKLGERGGKAMIEVLRNGDRLALEIQPRQMKRDDGETFWGLGVAVAAPTPPQRDAVLRYGPVAAVPAAFREGWHQAGELFAMIGRAFTGRVSLQNTVAGPVTIGRAANAYASNGPAWYLQLLAMLSLSLGILNLLPIPILDGGHLLYYLIELVKGSPVSERVMAAGHFVGLALIASLMGLAFYNDILNNLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJQ5</accession>
    <name>A0A0S2DJQ5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA polymerase sigma-E factor</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Sigma-70 family RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpoE</name>
        <name evidence="4" type="ORF">BV903_20475</name>
        <name evidence="6" type="ORF">D9T17_11635</name>
        <name evidence="5" type="ORF">FE772_16415</name>
        <name evidence="3" type="ORF">GLE_3319</name>
    </gene>
    <organism evidence="3 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">C3</strain>
        </source>
    </reference>
    <reference evidence="4 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">OH11</strain>
        </source>
    </reference>
    <reference evidence="5 10" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 10">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000062">
        <property type="protein sequence ID" value="OPD62060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000027">
        <property type="protein sequence ID" value="ROU06868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948205.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000027.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3319"/>
    <dbReference type="EnsemblBacteria" id="ALN58665">
        <property type="protein sequence ID" value="ALN58665"/>
        <property type="gene ID" value="GLE_3319"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62060">
        <property type="protein sequence ID" value="OPD62060"/>
        <property type="gene ID" value="BV903_20475"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3319"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3269"/>
    <dbReference type="OMA" id="VKSRIHE"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r4_2" evidence="2">
        <location>
            <begin position="114"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD62060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROU06868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="171" mass="19421" checksum="9951483E7B1DAD76" modified="2016-02-17" version="1">MTSLLANGDLAAARAGDTAALERVLRHSRQDLRRYAEFHCVINDVEDAVQESLITVSRKLRDLRVLECFVSWTFRIVKRECNRLKRGRRMFSGQPITEEIAPVVVPEPAEWRHDVAAALESLPAHYRQIVLLRDLEGLTVAEIGAELGLSREAVKSRLHRARVLAREYLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJW3</accession>
    <name>A0A0S2DJW3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Integron</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_16620</name>
        <name evidence="2" type="ORF">GLE_3367</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58713">
        <property type="protein sequence ID" value="ALN58713"/>
        <property type="gene ID" value="GLE_3367"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3367"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3317"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726811" evidence="1">
        <location>
            <begin position="23"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="130" mass="13884" checksum="73674C4E3575B90B" modified="2016-02-17" version="1">MNRTMVVCLGGALALLAVAAAAEPPASTPVGDIGAGGPCESIGEVVGLKAGRDGFLTVREGPGTGYAAVDRIESERRVRLCRSEGRWVSVMYPPPGSRMLCEPESADIRRYRGPCNFGWVHWNWIRIVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK52</accession>
    <name>A0A0S2DK52_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AMP nucleosidase</fullName>
            <ecNumber evidence="2">3.2.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">AMP nucleosidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BV903_16835</name>
        <name evidence="8" type="ORF">FE772_17650</name>
        <name evidence="6" type="ORF">GLE_3582</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">C3</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AMP + H2O = adenine + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:20129"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.2.2.4"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.2.2.4" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000045">
        <property type="protein sequence ID" value="OPD62760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948395.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3582"/>
    <dbReference type="EnsemblBacteria" id="ALN58926">
        <property type="protein sequence ID" value="ALN58926"/>
        <property type="gene ID" value="GLE_3582"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62760">
        <property type="protein sequence ID" value="OPD62760"/>
        <property type="gene ID" value="BV903_16835"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3582"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3526"/>
    <dbReference type="OMA" id="EYKYTKK"/>
    <dbReference type="OrthoDB" id="424615at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008714">
        <property type="term" value="F:AMP nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021826">
        <property type="entry name" value="DUF3412"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037153">
        <property type="entry name" value="YgdH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027820">
        <property type="entry name" value="YgdH_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11892">
        <property type="entry name" value="DUF3412"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14793">
        <property type="entry name" value="DUF4478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4478" evidence="5">
        <location>
            <begin position="16"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3412" evidence="4">
        <location>
            <begin position="340"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00031983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF11892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD62760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW27183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="460" mass="50920" checksum="6F5E2FF202813AE5" modified="2016-02-17" version="1">MTATPNATVLPTVNARIYPKGGLDVLSRDEVARLRDASTGIHDLLRRCALAVLTSGSASDDPRAARELYPDFDIEVHQQDRGMRIDLTRAPAMAFVDGEIIRGVAELLFAVVRDLAYTAIELGKGGGRDLESSDGLTDSVFGLLRNARILHPADPNLVVCWGGHSISRDEYIYTKQVGYELGLRGLDICTGCGPGAMKGPMKGATIAHAKQRRRAMRYIGITEPGIIAAESPNPIVNHLVIMPDIEKRLEAFVRMGHGIIVFPGGVGTAEEILYLLGILLREENAGLPFPLILTGPTASAPYFEQIDKFLRLTLGEVATQRYEIIVGDPERVARAMSQGIRKVREYRIEHKDSFFFNWSIDIPLTFQKPFVPTHEAMAALDLHHGRKPHELAADLRRAFSGIVAGNVKEDGMRRIEEFGPFEIHGDPDMMQSLDALLRAFVEQRRMKIAGEYRPCYRVVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKA4</accession>
    <name>A0A0S2DKA4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glutaredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">grxD</name>
        <name evidence="12" type="ORF">D9T17_10180</name>
        <name evidence="11" type="ORF">FE772_17675</name>
        <name evidence="10" type="ORF">GLE_3587</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">OH11</strain>
        </source>
    </reference>
    <reference evidence="11 15" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 15">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glutaredoxin family. Monothiol subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000023">
        <property type="protein sequence ID" value="ROU07316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948398.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3587"/>
    <dbReference type="EnsemblBacteria" id="ALN58931">
        <property type="protein sequence ID" value="ALN58931"/>
        <property type="gene ID" value="GLE_3587"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3587"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3531"/>
    <dbReference type="OMA" id="KGTKLMP"/>
    <dbReference type="OrthoDB" id="2001991at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097573">
        <property type="term" value="F:glutathione oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03028">
        <property type="entry name" value="GRX_PICOT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033658">
        <property type="entry name" value="GRX_PICOT-like"/>
    </dbReference>
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        <property type="entry name" value="Monothiol_GRX"/>
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    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
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        <property type="entry name" value="Thioredoxin-like_sf"/>
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        <property type="entry name" value="PTHR10293"/>
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    </dbReference>
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        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TIGR00365"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="17"/>
            <end position="82"/>
        </location>
    </feature>
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        <location>
            <begin position="85"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="22"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
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        <location>
            <position position="60"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="72"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:57925"/>
        </ligand>
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        <source>
            <dbReference type="ARBA" id="ARBA00009630"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
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            <dbReference type="ARBA" id="ARBA00023014"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR005894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
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    </evidence>
    <evidence type="ECO:0000256" key="8">
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN58931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW27187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROU07316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="107" mass="11809" checksum="DE82D8623A3C2917" modified="2016-02-17" version="1">MSSVIERIQTEVESHPVVLFMKGTAQFPMCGFSSRAVQALKAAGATALHTVNVLEDPEIRANLPRYSNWPTFPQLFIHGELIGGCDITLELYESGELARMISETQSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKI2</accession>
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        </submittedName>
    </protein>
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    </gene>
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        <lineage>
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    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN58799">
        <property type="protein sequence ID" value="ALN58799"/>
        <property type="gene ID" value="GLE_3454"/>
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    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58799.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW27082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="402" mass="43642" checksum="5788169D4F07B8D8" modified="2016-02-17" version="1">MSAPIDVSDRPAGSVSDPGRYRLDLTATHSHVLTIEPGRGNLILGPARMGKKADLHVAADEAIQWRAFEPFATPAGSPWPRYIDYRGNDSGFFAWSQRRGIEQFTWAPAFADARAVDGGGADIRSLQIRLDEVSGHLRLSLPERSSLGLYGDLSRFTAVGAAPRSLSLLPALSRRRSDAPYALPGLGLLHAATSLSLHAGPLGQPISLAGIERFAALRSLSLWGGFSDWDALAKLTDLDSLEIRFAPQLDGLPPLDAWPKLDRFIAYNIDDAAGKTLKAQLKARAKLREWSDYASVSQLRKPEWWQREYGRPFAGWSGRNAKAANAAYDTALQALEQAGDAAAAKAAVVAFAAHFNDLKGIETGEREDIGEAVWQFSQLAHVAALGVGEEQALGWFDEARDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKL5</accession>
    <name>A0A0S2DKL5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Aerobic C4-dicarboxylate transport protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="10">Dicarboxylate/amino acid:cation symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dctA</name>
        <name evidence="10" type="ORF">FE772_18420</name>
        <name evidence="9" type="ORF">GLE_3740</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW27319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948513.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3740"/>
    <dbReference type="EnsemblBacteria" id="ALN59084">
        <property type="protein sequence ID" value="ALN59084"/>
        <property type="gene ID" value="GLE_3740"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3740"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3685"/>
    <dbReference type="OMA" id="AQIYGIP"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046942">
        <property type="term" value="P:carboxylic acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018107">
        <property type="entry name" value="Na-dicarboxylate_symporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865">
        <property type="entry name" value="PTHR42865"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="SSF118215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00713">
        <property type="entry name" value="NA_DICARBOXYL_SYMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00714">
        <property type="entry name" value="NA_DICARBOXYL_SYMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0769">Symport</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="39"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="152"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="229"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="349"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="413"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="428"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN59084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="442" mass="46789" checksum="34DD1206336B59AB" modified="2016-02-17" version="1">MKKSGSHFYLWVIGAIILGGLIGHFFPEFGVKLKPLGDGFIALIKMLIGPIIFLTVVLGIAGVADVKKVGRVGVKAILYFEVVSTIALVIGLVVVNTLKPGAGFNADPAKLDPALVAKATDYAHKAEQQSTVDFLLHIIPKTFTDAFTGDGSLLQVLLLAVLFGFSLLHMGKTGEKVMDLLEPLSKVFFGIMSMIMKLAPIGAGAAMAFTIGEFGVGALGPLMKLMGSFYLTCALFVLIVLGLIARFTGFSIIRFIRYIRDELLLVLGTSSSESALVPLMRKLERLGCSKPVVGLVVPSGYSFNLDGTNIYLTMAAIFVAQALGVELTLTQEITLLAVAMLTSKGASGVTGAGFITLAATLHVVPAVPVAGLALILGIDRFMSEARALTNIIGNGVATVVVARWENELDRDQLNRELLNPPSATELDADLPSDHHGPLGEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKN2</accession>
    <name>A0A0S2DKN2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3606 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_18295</name>
        <name evidence="1" type="ORF">GLE_3714</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948494.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3714"/>
    <dbReference type="EnsemblBacteria" id="ALN59058">
        <property type="protein sequence ID" value="ALN59058"/>
        <property type="gene ID" value="GLE_3714"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3714"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3659"/>
    <dbReference type="OMA" id="LNCDEYE"/>
    <dbReference type="OrthoDB" id="2014968at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022037">
        <property type="entry name" value="DUF3606"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12244">
        <property type="entry name" value="DUF3606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="60" mass="6905" checksum="2FCF8A90E778173C" modified="2016-02-17" version="1">MSDDSDRRGPQDRARISLEQAHELRYWTERFGVDERRLREAVAAVGVSADAVERYLRANG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL10</accession>
    <name>A0A0S2DL10_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3859</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59202">
        <property type="protein sequence ID" value="ALN59202"/>
        <property type="gene ID" value="GLE_3859"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3859"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="97" mass="10858" checksum="799C068EC2C889BE" modified="2016-02-17" version="1">MAVQRAAAIQRQVHPRTPDWPPRAALAASVPSPPPAGEPSARPAGRGTSSPRWPRNRGRPRPRIRCRARRRRHRSRRIGSFVALEIGPPDGRPRWLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL54</accession>
    <name>A0A0S2DL54_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glutathione synthetase</fullName>
            <ecNumber evidence="10">6.3.2.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">GSH synthetase</fullName>
            <shortName evidence="10">GSH-S</shortName>
            <shortName evidence="10">GSHase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Glutathione synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 13" type="primary">gshB</name>
        <name evidence="14" type="ORF">BV903_14855</name>
        <name evidence="16" type="ORF">D9T17_08640</name>
        <name evidence="15" type="ORF">FE772_19445</name>
        <name evidence="13" type="ORF">GLE_3964</name>
    </gene>
    <organism evidence="13 17">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 17">C3</strain>
        </source>
    </reference>
    <reference evidence="14 18" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 18">B25</strain>
        </source>
    </reference>
    <reference evidence="16 19" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 19">OH11</strain>
        </source>
    </reference>
    <reference evidence="15 20" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 20">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + glutathione + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13557"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the prokaryotic GSH synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.3" evidence="10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000038">
        <property type="protein sequence ID" value="OPD63165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000021">
        <property type="protein sequence ID" value="ROU07585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948679.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3964"/>
    <dbReference type="EnsemblBacteria" id="ALN59306">
        <property type="protein sequence ID" value="ALN59306"/>
        <property type="gene ID" value="GLE_3964"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63165">
        <property type="protein sequence ID" value="OPD63165"/>
        <property type="gene ID" value="BV903_14855"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3964"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3901"/>
    <dbReference type="OMA" id="WMRKDPP"/>
    <dbReference type="OrthoDB" id="878336at2"/>
    <dbReference type="UniPathway" id="UPA00142">
        <property type="reaction ID" value="UER00210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004363">
        <property type="term" value="F:glutathione synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00162">
        <property type="entry name" value="GSH_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006284">
        <property type="entry name" value="Glut_synth_pro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004218">
        <property type="entry name" value="GSHS_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004215">
        <property type="entry name" value="GSHS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21621:SF4">
        <property type="entry name" value="PTHR21621:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02955">
        <property type="entry name" value="GSH-S_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02951">
        <property type="entry name" value="GSH-S_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01380">
        <property type="entry name" value="glut_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="3 10 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="12">
        <location>
            <begin position="124"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN59306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OPD63165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW27489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROU07585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="317" mass="34610" checksum="08601AD1A5F8E4BD" modified="2016-02-17" version="1">MPLDIVVVMDPIGSIKIAKDSTFAMLLEGQRRGHRLWYVKPGGLSLDGGRALANVAPLRVRDDKNGWHELGDWSQIELGSAHVILMRKDPPVDAEYLHDTQILSVAQRAGAFVVNDPQGLRDYNEKLAALLFPQCCIDTLVSRDAGELKAFVQRHGQAVLKPLDGMGGRSIFRAAAGEPNLNVILETLGDGGRHLVMAQKFLPDIKDGDKRVLLVDGVPVDYALARIPQGDEFRGNLAAGGRGEGRPLSERDRWIAAQVGPEMRERGMLFVGLDVIGDYMTELNVTSPTCIRELDEQFGLNIAGLLFDAIEARLSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL67</accession>
    <name>A0A0S2DL67_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amylo-alpha-1,6-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.33</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_18285</name>
        <name evidence="3" type="ORF">GLE_3711</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.33" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948492.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3711"/>
    <dbReference type="EnsemblBacteria" id="ALN59055">
        <property type="protein sequence ID" value="ALN59055"/>
        <property type="gene ID" value="GLE_3711"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3711"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3656"/>
    <dbReference type="OMA" id="EIPHTPY"/>
    <dbReference type="OrthoDB" id="70058at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004135">
        <property type="term" value="F:amylo-alpha-1,6-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032790">
        <property type="entry name" value="GDE_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032856">
        <property type="entry name" value="GDE_N_bis"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06202">
        <property type="entry name" value="GDE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14742">
        <property type="entry name" value="GDE_N_bis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GDE_N_bis" evidence="2">
        <location>
            <begin position="15"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="GDE_C" evidence="1">
        <location>
            <begin position="274"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="705" mass="77270" checksum="22B5EA5723D15C6E" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLE3</accession>
    <name>A0A0S2DLE3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Arsenical resistance protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Arsenical resistance protein ArsH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">arsH</name>
        <name evidence="3" type="ORF">FE772_18180</name>
        <name evidence="2" type="ORF">GLE_3688</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948475.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3688"/>
    <dbReference type="EnsemblBacteria" id="ALN59032">
        <property type="protein sequence ID" value="ALN59032"/>
        <property type="gene ID" value="GLE_3688"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3688"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3632"/>
    <dbReference type="OMA" id="YKFTLLV"/>
    <dbReference type="OrthoDB" id="1818437at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014063">
        <property type="entry name" value="Arsenate-R_ArsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43590">
        <property type="entry name" value="PTHR43590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02690">
        <property type="entry name" value="resist_ArsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_red" evidence="1">
        <location>
            <begin position="29"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="264" mass="28880" checksum="91CCF152F6EFC62E" modified="2016-02-17" version="1">MTPPPLPLLDPAALQIPEPARLGAAAHAPRILILYGSLRPQSYSRKLALEAQRLLQRFGADARVFDPHELPMLDSVAASHPKVQELRELSRWSEGQVWVSPERHGAVTAVFKNQIDWLPLEDGSVRPTQGRTLAVMQVCGGSQSFNVVNALRVLGRWMRMIVVPNQSSVAKAWQEFDEDGRMKPSSYYDRVVDVMEELVKFTLLTRGHSDYLTDRYSERKNDAAAHRLAAAAGAIEATTANATTLPASAPAPTAKNACCAGACT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLM0</accession>
    <name>A0A0S2DLM0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase I</fullName>
            <ecNumber evidence="6">2.1.1.198</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA 2'-O-ribose C1402 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">rRNA (cytidine-2'-O-)-methyltransferase RsmI</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">rsmI</name>
        <name evidence="9" type="ORF">FE772_20310</name>
        <name evidence="8" type="ORF">GLE_4142</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(1402) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42924"/>
            <dbReference type="Rhea" id="RHEA-COMP:10285"/>
            <dbReference type="Rhea" id="RHEA-COMP:10286"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.198"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the methyltransferase superfamily. RsmI family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.198" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948820.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4142"/>
    <dbReference type="EnsemblBacteria" id="ALN59484">
        <property type="protein sequence ID" value="ALN59484"/>
        <property type="gene ID" value="GLE_4142"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4142"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4084"/>
    <dbReference type="OMA" id="RTMVFFE"/>
    <dbReference type="OrthoDB" id="1059309at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070677">
        <property type="term" value="F:rRNA (cytosine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000453">
        <property type="term" value="P:enzyme-directed rRNA 2'-O-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11648">
        <property type="entry name" value="RsmI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01877">
        <property type="entry name" value="16SrRNA_methyltr_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008189">
        <property type="entry name" value="rRNA_ssu_MeTfrase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018063">
        <property type="entry name" value="SAM_MeTrfase_RsmI_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46111">
        <property type="entry name" value="PTHR46111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005917">
        <property type="entry name" value="MTase_YraL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00096">
        <property type="entry name" value="TIGR00096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01296">
        <property type="entry name" value="RSMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="7">
        <location>
            <begin position="6"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW27633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="276" mass="28930" checksum="2EFB475FEAD098D8" modified="2016-02-17" version="1">MQTPGTLHIVATPIGNLGDLSPRALETLRTVAAVCAEDTRHTRQLLSHFGLERPLLALHQHNEEQQAAQLVARLQAGDSLALVSDAGTPLVSDPGFRLVRAARAAAIKVSPVPGACAAIAALSVAGLASDRFAFEGFLPAKASARRERLGKLAAEPRTLLFYESAHRIEEALDDMAAAFGGARAAVLARELTKLFETVLDGPLEALAAQVKADPNQRKGEFVVIVEGAGDDADAKVIEGKRLYAKLSEHLPPSTAAKLAAELSGAPRKALYGSGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLN5</accession>
    <name>A0A0S2DLN5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Indole-3-glycerol phosphate synthase</fullName>
            <shortName evidence="8">IGPS</shortName>
            <ecNumber evidence="8">4.1.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">trpC</name>
        <name evidence="11" type="ORF">BV903_04555</name>
        <name evidence="12" type="ORF">FE772_20905</name>
        <name evidence="10" type="ORF">GLE_4270</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">C3</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:23476"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="EC" id="4.1.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TrpC family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.48" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000008">
        <property type="protein sequence ID" value="OPD65194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948918.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000008.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4270"/>
    <dbReference type="EnsemblBacteria" id="ALN59611">
        <property type="protein sequence ID" value="ALN59611"/>
        <property type="gene ID" value="GLE_4270"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65194">
        <property type="protein sequence ID" value="OPD65194"/>
        <property type="gene ID" value="BV903_04555"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4270"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4208"/>
    <dbReference type="OMA" id="RGPHDLI"/>
    <dbReference type="OrthoDB" id="1789381at2"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00043"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004425">
        <property type="term" value="F:indole-3-glycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00331">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00134_B">
        <property type="entry name" value="IGPS_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045186">
        <property type="entry name" value="Indole-3-glycerol_P_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013798">
        <property type="entry name" value="Indole-3-glycerol_P_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001468">
        <property type="entry name" value="Indole-3-GlycerolPSynthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22854">
        <property type="entry name" value="PTHR22854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00218">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00614">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="7 8 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="IGPS" evidence="9">
        <location>
            <begin position="5"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OPD65194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW27734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="263" mass="28592" checksum="D9497FE04D1263E3" modified="2016-02-17" version="1">MSDILNTIIARKHEEIQQRSRVRSLDDLRARARAQAPARGFVQAIRDKHAAGTAAVIAEVKKASPSKGVIRPDFHPAQIARSYQAGGAACLSVLTDVDFFQGSNAYLAEAREACALPVLRKDFTVDPYQVYEARAIGADAILLIVAALEDGPMIEMAGLAMDLGMDVLVEVHDIDELERALQTDCELIGVNNRNLRTFEVSLDTTLALRSAVPRDRTLVTESGIATAGDVARMREAGVETFLVGESFMRERDPGTALQRLFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLW5</accession>
    <name>A0A0S2DLW5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RelE/ParE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4107</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4107"/>
    <dbReference type="EnsemblBacteria" id="ALN59449">
        <property type="protein sequence ID" value="ALN59449"/>
        <property type="gene ID" value="GLE_4107"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4107"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4049"/>
    <dbReference type="OMA" id="DHYRAND"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="89" mass="10089" checksum="04F6DB2540985FBA" modified="2016-02-17" version="1">MAEDFARILDHLDRHDAARREQRIDGILRAIDVLSDNPLIGRPAEAELRELVIGRDVSGYVALYRYLSEFDTVLILAIRAQREAGYAPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM41</accession>
    <name>A0A0S2DM41_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4275</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59616">
        <property type="protein sequence ID" value="ALN59616"/>
        <property type="gene ID" value="GLE_4275"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4275"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4213"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="37" mass="3851" checksum="287446BF316FDFC1" modified="2016-02-17" version="1">MAGDSPQVFMVFADEPVELVHALLHVDSGIGPSKGVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMD1</accession>
    <name>A0A0S2DMD1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Type IV pilus expression regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pilR</name>
        <name evidence="10" type="ORF">GLE_4113</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948794.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4113"/>
    <dbReference type="EnsemblBacteria" id="ALN59455">
        <property type="protein sequence ID" value="ALN59455"/>
        <property type="gene ID" value="GLE_4113"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4113"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4055"/>
    <dbReference type="OMA" id="QAPIYIS"/>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Response regulatory" evidence="9">
        <location>
            <begin position="6"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="8">
        <location>
            <begin position="137"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="389"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="392"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="472" mass="50929" checksum="9F3139D831CDE044" modified="2016-02-17" version="1">MAETRSALVVDDERDIRELLVMTLGRMGLRCDTASGLNEARSQLLRNRYDLCLTDMRLPDGSGMDLVAEISQKHPNTPVAMITAFGNVEAAVEALKAGAFDFVAKPVDLSVLRDLVRHALELHETRRSASEAVGSRLYGESPAMIKLRQTIGKVARSQAPVYIAGESGVGKELVARTIHSEGGRADGPFVPVNCGAIPAELMESEFFGHKKGSFTGAHADKPGLFQAADGGTLFLDEVAELPLAMQVKLLRAIQEKSIRPVGAQAEVTVDVRILSATHKDLAALVAEGRFRQDLYYRINVIELRVPPLRERLDDLPGLAAKILHRLAGNQGRPVPRLGDDALEALRAYNFPGNVRELENILERALALAEGEVLSAGDLRLPRLATQAPPGAVAPGAAPPAAGQPVPPGAVDPRTLNPRDTATSALPSYIEEIERAAIQQALQENRYNKTRTAAALGITFRALRYKLKKLGID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMK6</accession>
    <name>A0A0S2DMK6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-binding response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Response regulator transcription factor</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Two-component system, OmpR family, response regulator PhoP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">phoP</name>
        <name evidence="7" type="ORF">BV903_23205</name>
        <name evidence="9" type="ORF">D9T17_22155</name>
        <name evidence="8" type="ORF">FE772_21235</name>
        <name evidence="5" type="ORF">GLE_4342</name>
        <name evidence="6" type="ORF">LEN_0875</name>
        <name evidence="10" type="ORF">SAMN05421681_101384</name>
    </gene>
    <organism evidence="5 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 11">C3</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2016" name="DNA Res." volume="0" first="0" last="0">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer, Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M497-1</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="3">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">ATCC 29487</strain>
        </source>
    </reference>
    <reference evidence="6 14" key="4">
        <citation type="journal article" date="2017" name="DNA Res." volume="24" first="169" last="177">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
            <dbReference type="PubMed" id="28065880"/>
            <dbReference type="DOI" id=".1093/dnares/dsw055"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 14">M497-1</strain>
        </source>
    </reference>
    <reference evidence="7 13" key="5">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 13">B25</strain>
        </source>
    </reference>
    <reference evidence="9 15" key="6">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 15">OH11</strain>
        </source>
    </reference>
    <reference evidence="8 16" key="7">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 16">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP014940">
        <property type="protein sequence ID" value="BAV96362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000079">
        <property type="protein sequence ID" value="OPD61530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000055">
        <property type="protein sequence ID" value="ROU04825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNOG01000001">
        <property type="protein sequence ID" value="SDW19819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_031372686.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000055.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4342"/>
    <dbReference type="EnsemblBacteria" id="ALN59683">
        <property type="protein sequence ID" value="ALN59683"/>
        <property type="gene ID" value="GLE_4342"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAV96362">
        <property type="protein sequence ID" value="BAV96362"/>
        <property type="gene ID" value="LEN_0875"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61530">
        <property type="protein sequence ID" value="OPD61530"/>
        <property type="gene ID" value="BV903_23205"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDW19819">
        <property type="protein sequence ID" value="SDW19819"/>
        <property type="gene ID" value="SAMN05421681_101384"/>
    </dbReference>
    <dbReference type="KEGG" id="lem:LEN_0875"/>
    <dbReference type="KEGG" id="lez:GLE_4342"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4281"/>
    <dbReference type="OMA" id="HHQQVVP"/>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000183696">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000218824">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="124"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="124"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAV96362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD61530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW27791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROU04825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDW19819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000183696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000218824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="227" mass="25361" checksum="09D3E197B99DE01E" modified="2016-02-17" version="1">MRILLVEDEAPLRETLAARLKREGFAVDAAQDGEEGLYMGREVPFDLGIIDLGLPKMSGMELIKALRDEGKKFPVLILTARSSWQDKVEGLKQGADDYLVKPFHVEELLARLNALVRRAAGWSKPTLECGPVMLDLAAQTVSVNGGNVDLTSYEYKVLEYLMMHAGELVSKADLTEHIYQQDFDRDSNVLEVFIGRLRKKLDPDGALKPIETVRGRGYRFAIPRSGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMR8</accession>
    <name>A0A0S2DMR8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AraC family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_21985</name>
        <name evidence="4" type="ORF">GLE_4501</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
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            <authorList>
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            </authorList>
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            <strain evidence="5 7">YC36</strain>
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    <dbReference type="EnsemblBacteria" id="ALN59842">
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
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    </evidence>
    <sequence length="337" mass="36706" checksum="2A44F4D7A1A4B992" modified="2016-02-17" version="1">MELFSLTIAGFSIIVAALLWLTYVAFLKIPGKSAYSILSCTVLLGALVALQLGHLLYFTGGPAPLDTLAYQIALFVAPPSFFFFGRWALLPDEPFRPGLLLALLPIALLPIPRLDVSLPMLFAVGAGFALWLGRLVYGLRVQRKQFRFEFFWFGVMSAFAVGVLALGFALPYIDPVWFYRFYCNAIGAAFAIMVVALIAHPDLIADLTEAAQLRYGKSTLRDADVDGLLARLAALMADPKVYRNETLTLSTLAADLGVTGHQLSELVNTRLGMGFPRYVRERRVAAAKAMLVAEPNASILAVGMDTGFKSQSTFYAAFKEVTGQSPGDYRKANAKAS</sequence>
</entry>
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        <source>
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    <sequence length="421" mass="43461" checksum="CBB086594E5B41AF" modified="2016-02-17" version="1">MRAVSRWQIVGLSINDVIGSGIYLLPATAAMLLGPASLWAVLLAGFAVALLVLCYAQAASYFDQPGGGYLYAREAFGPFAGFEVGWMLLVTRISTAASLSNGLAEAVALFWPAAKAGPARVFIVAGSLGLLVLINVLGVRTAARAGVALAIGKLVPLVLFVAIGAFYFDPALLHSDAPLPVDHLGEAALLLLFAYAGFENLPAAAGEYRNPRRDVPFALLTMIVLVTIVYFAVQLVALGTLPGIAQSTSPLAEAAAHFSGTGLALVLTVGAAISILGTNSNTVMMGPRYLLALSRDGYGPRALGAIHPRFHTPARAVLLLGAIALALALTGSFQQLALLSVVARLCTYIGTAVSVLVLQKRHRGREGALHLPGGPLIPIAAIVLSLGLLASASVKNLIAAAIALVVGAVIYKLRRAPEAAV</sequence>
</entry>
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="119" mass="12357" checksum="54518F3CD0B6150B" modified="2016-02-17" version="1">MPARSALANVMRHLVFGVLIAVMLFKPVLAFAGEVGELDDLVPDAALVFDAAHAGGLPDQDGCGDLQRHLTHCCAVQAALLPRIELGLLAPSPASPLPARATAFVAADPTQPLRPPIHA</sequence>
</entry>
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    <accession>A0A0S2DMX4</accession>
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        </submittedName>
    </protein>
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        <name evidence="7" type="ORF">FE772_21555</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="protein sequence ID" value="QCW27849.1"/>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_4412"/>
    <dbReference type="EnsemblBacteria" id="ALN59753">
        <property type="protein sequence ID" value="ALN59753"/>
        <property type="gene ID" value="GLE_4412"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4412"/>
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    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:aminopeptidase activity"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="M28_fam"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="PTHR12147"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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            <begin position="24"/>
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</entry>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">C3</strain>
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    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">YC36</strain>
        </source>
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    <evidence type="ECO:0000259" key="1">
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="ALN60036.1"/>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
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</entry>
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</entry>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">YC36</strain>
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    </feature>
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            <begin position="45"/>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="181" mass="20266" checksum="86D1E425DEBE0E66" modified="2016-02-17" version="1">MRNPLQEQLLKAGLAKKSQATQAVREQNKQRQAKNPQAPSAEQAEAERARAEKVERDRALEAQRKAQARAHELRAQIQQIVEQGKVKRKGEIAYRFDDGEAIRTVYVDTALRAQLASGALAIVRHGEDYELVPRAVAEKVRERDAAMVVLDHGASKTAPAEPLSEDDAYYAQFQVPDDLVW</sequence>
</entry>
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    <accession>A0A0S2DNI5</accession>
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            <begin position="1"/>
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        </location>
    </feature>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN60049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNN5</accession>
    <name>A0A0S2DNN5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heavy metal transporter family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4823</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
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        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
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        <location>
            <begin position="51"/>
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="119" mass="13319" checksum="C96A000ABD617503" modified="2016-02-17" version="1">MDPAAKAAQASNDMNPQIELNLALILFIPWFSILAWLFWAYPRQPRSAARTVFDSASLVLATLAAFWGMHWGMYNADPHAGAIWKQVLATSVAYGLFLAVMTAALLARWRWLRARRVAA</sequence>
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<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
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    <gene>
        <name evidence="2" type="ORF">FE772_23805</name>
        <name evidence="1" type="ORF">GLE_4904</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949404.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60245">
        <property type="protein sequence ID" value="ALN60245"/>
        <property type="gene ID" value="GLE_4904"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4904"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4835"/>
    <dbReference type="OMA" id="ACVQVFA"/>
    <dbReference type="OrthoDB" id="1769199at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024787">
        <property type="entry name" value="EcsC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41260">
        <property type="entry name" value="PTHR41260"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12787">
        <property type="entry name" value="EcsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="291" mass="30777" checksum="AA6687469EAF63CB" modified="2016-02-17" version="1">MTQDSDPLQHPADAADLKRAVALLETPSITARMAALAGAPIEFGMSKLPKFAHERIHKIVHAALHRAASAALSTVGDAPSKGASTKTHKLAAAVSGAAGGFFGMAGLAVELPVTTVIMMRSVADIARSEGFSVSEPWVRAACVEVFAFGGNSKSDDAAESGYYASRGMLSELTKGATRELVHLAGHRGAHELTQAYAKKQTAAWMAKLIDTVATRFGIVITEKTAAQIVPVLGAATAATMNVLFTNHYQDMARGHFIVKRLELRYGAQAVERAYRRVQAGEALALPERVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPA3</accession>
    <name>A0A0S2DPA3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cytochrome d ubiquinol oxidase, subunit I</fullName>
            <ecNumber evidence="14">1.10.3.-</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="15">Cytochrome ubiquinol oxidase subunit I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">cyaA</name>
        <name evidence="15" type="ORF">FE772_23935</name>
        <name evidence="14" type="ORF">GLE_4934</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">C3</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the cytochrome ubiquinol oxidase subunit 1 family.</text>
    </comment>
    <dbReference type="EC" id="1.10.3.-" evidence="14"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057950327.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4934"/>
    <dbReference type="EnsemblBacteria" id="ALN60275">
        <property type="protein sequence ID" value="ALN60275"/>
        <property type="gene ID" value="GLE_4934"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4934"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4863"/>
    <dbReference type="OMA" id="WAIIFNP"/>
    <dbReference type="OrthoDB" id="271551at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070069">
        <property type="term" value="C:cytochrome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002585">
        <property type="entry name" value="Cyt-d_ubiquinol_oxidase_su_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30365">
        <property type="entry name" value="PTHR30365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01654">
        <property type="entry name" value="Cyt_bd_oxida_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006446">
        <property type="entry name" value="Cyt_quinol_oxidase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 12" id="KW-0349">Heme</keyword>
    <keyword evidence="10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="217"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="322"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="405"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="437"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR006446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN60275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW28241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="466" mass="51825" checksum="E1334BEDEF19B5C2" modified="2016-02-17" version="1">MDALLLSRIQFGFVISFHILFPAFTIGLASWLAFVEWRWLRTRDTLWRDLFFFWTKVFAVSFGMGVVSGIVMSFQFGTNWAVLSEQAGSILGPLLSYEVLTAFFLEATFLGVMLFGWGRVSERMHFLATCMVALGTLISTFWIISANSWMQTPTGHRIVDGVFVPDDWWAIVFNPSFPYRLAHMVLAAFITTCFVIGGTGASYLLRGIHVEAGKRMLKAAVVFAAVTVPVQVFVGDLHGLNVREHQPIKVAAMEAHWESNPPGEGVPLILFAVPNEKAERNDLEIAVPKLGSLILTHTLDGDIQPLKSVPASERPPVKPVFYAFRVMVGLGMAMLALVACSLWLLWRRRLYESRAVLWGWRVMIMSGFAAILAGWYVVEIGRQPYVIYGLLRTADAVSPVEAASVMTSLIVFAVVYFTVFGAGFRYLVKLIRKGPHPHEPPPQRMHGDKTPARPLSVPDESTEAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPD1</accession>
    <name>A0A0S2DPD1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_12195</name>
        <name evidence="4" type="ORF">FE772_24220</name>
        <name evidence="2" type="ORF">GLE_4996</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000029">
        <property type="protein sequence ID" value="OPD63678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949472.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000029.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60337">
        <property type="protein sequence ID" value="ALN60337"/>
        <property type="gene ID" value="GLE_4996"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63678">
        <property type="protein sequence ID" value="OPD63678"/>
        <property type="gene ID" value="BV903_12195"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4996"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4924"/>
    <dbReference type="OrthoDB" id="2205069at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="114" mass="11940" checksum="3B3CE9E4BC9359F1" modified="2016-02-17" version="1">MTFNDWLPALLSQAAFMTPSLLAYITGIVLCLSWRRRIGVGATYAVAAFALLVFGLALSLLGQVWIYRAMADGISASSTSLGHSVIGVAHVLISLVSTGLLIAAVLAKRPPSPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPF1</accession>
    <name>A0A0S2DPF1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TonB family C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4928</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4928"/>
    <dbReference type="EnsemblBacteria" id="ALN60269">
        <property type="protein sequence ID" value="ALN60269"/>
        <property type="gene ID" value="GLE_4928"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4928"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4857"/>
    <dbReference type="OMA" id="RWRAFIP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="331" mass="35971" checksum="D40AF91A7DF81FA0" modified="2016-02-17" version="1">MGRCIADNGPLGRWMTQPVCYGCRLDDFQSSLLQRRFSFSSSKGIMRQMKAMKGWAALVLIAALAASAPAMAQGRAEVRKQAEMSMVVTGTVRIAADGRVEGVSVDREAQVPADVAKLIGGAVPRWRFEPLAEPAPSADVAMTLRVAVRRDPQAQTDDAYVMRIVSASFGEPEPPFDHSTPPPTYPTRAAMQGVPATVYVVARFGRDGKVRESFVEQVNLYRVGTQAQMEWFRKSFAEATLAAVRRWSIVPPSQGEEAGNDSWLVRVPVTFVLPGHQDKAYGQWDVYVPGPRQRAPWARQTADAGVDAMAGNGPRLLGGGRRLLDGLDGNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPK5</accession>
    <name>A0A0S2DPK5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2-dehydro-3-deoxy-phosphogluconate aldolase</fullName>
            <ecNumber evidence="3">4.1.2.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">eda</name>
        <name evidence="5" type="ORF">GLE_5189</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-dehydro-3-deoxy-6-phospho-D-gluconate = D-glyceraldehyde 3-phosphate + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:17089"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:57569"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KHG/KDPG aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.14" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5189"/>
    <dbReference type="EnsemblBacteria" id="ALN60530">
        <property type="protein sequence ID" value="ALN60530"/>
        <property type="gene ID" value="GLE_5189"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5189"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5109"/>
    <dbReference type="OMA" id="FFPAEYC"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008675">
        <property type="term" value="F:2-dehydro-3-deoxy-phosphogluconate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00452">
        <property type="entry name" value="KDPG_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000887">
        <property type="entry name" value="Aldlse_KDPG_KHG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031337">
        <property type="entry name" value="KDPG/KHG_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031338">
        <property type="entry name" value="KDPG/KHG_AS_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30246">
        <property type="entry name" value="PTHR30246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01081">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01182">
        <property type="entry name" value="eda"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00159">
        <property type="entry name" value="ALDOLASE_KDPG_KHG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00160">
        <property type="entry name" value="ALDOLASE_KDPG_KHG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="211" mass="21244" checksum="76A57F62820CB728" modified="2016-02-17" version="1">MQDLQKRVGAVLALAPVVPVLVIDDLAHAVPLARALVAGGLPAIEVTLRTPVALEAVRAIAAEVEGAAVGVGSVRRPQDFVDALKAGATFAVSPGSSPGLIAAAREIDLPWLPGAATASEAMALLEQGYTQLKFFPAESIGGATALKSLGGPLPELRFCATGGIGANNAREYLALANVPCVGGSWVAPAAAVKAGDWAKVEALAREAAALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPY4</accession>
    <name>A0A0S2DPY4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949674.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60602">
        <property type="protein sequence ID" value="ALN60602"/>
        <property type="gene ID" value="GLE_5261"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5261"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5180"/>
    <dbReference type="OMA" id="YLRWEGS"/>
    <dbReference type="OrthoDB" id="962068at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595954" evidence="1">
        <location>
            <begin position="29"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="654" mass="69857" checksum="A7F6A938AA9A8E72" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPY5</accession>
    <name>A0A0S2DPY5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Beta sliding clamp</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">dnaN</name>
        <name evidence="15" type="ORF">BV903_04940</name>
        <name evidence="16" type="ORF">FE772_25795</name>
        <name evidence="14" type="ORF">GLE_5338</name>
    </gene>
    <organism evidence="14 17">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">C3</strain>
        </source>
    </reference>
    <reference evidence="15 18" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 18">B25</strain>
        </source>
    </reference>
    <reference evidence="16 19" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 19">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Forms a ring-shaped head-to-tail homodimer around DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the beta sliding clamp family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000009">
        <property type="protein sequence ID" value="OPD65085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949732.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5338"/>
    <dbReference type="EnsemblBacteria" id="ALN60679">
        <property type="protein sequence ID" value="ALN60679"/>
        <property type="gene ID" value="GLE_5338"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65085">
        <property type="protein sequence ID" value="OPD65085"/>
        <property type="gene ID" value="BV903_04940"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5338"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5255"/>
    <dbReference type="OMA" id="YLIMPVR"/>
    <dbReference type="OrthoDB" id="1040142at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00140">
        <property type="entry name" value="beta_clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001001">
        <property type="entry name" value="DNA_polIII_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022635">
        <property type="entry name" value="DNA_polIII_beta_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022637">
        <property type="entry name" value="DNA_polIII_beta_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022634">
        <property type="entry name" value="DNA_polIII_beta_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30478">
        <property type="entry name" value="PTHR30478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00712">
        <property type="entry name" value="DNA_pol3_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02767">
        <property type="entry name" value="DNA_pol3_beta_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02768">
        <property type="entry name" value="DNA_pol3_beta_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000804">
        <property type="entry name" value="DNA_pol_III_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00480">
        <property type="entry name" value="POL3Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00663">
        <property type="entry name" value="dnan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 10" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="6 10 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_pol3_beta" evidence="11">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_2" evidence="12">
        <location>
            <begin position="129"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_3" evidence="13">
        <location>
            <begin position="247"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN60679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OPD65085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QCW28552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="366" mass="41030" checksum="5B2C76C479A0D7AC" modified="2016-02-17" version="1">MRFSLQREVFLKPLAQVVNVVERRQTLPVLANLLVQVKDGQLSLTGTDLEVEMISRVNVDDAKDGETTIPARKLFEIVRALPDGSKVTVSQTAEKITVQAGRSRFTLSSLPANDFPSIDEVEATERVRVPEAALKELIERTAFAMAQQDVRYYLNGLLFDLRETSLRCVATDGHRLALCEAAYEGGAQTKRQIIVPRKGVQELQRLLEGGDREVELEMGRGHIRIKRDDVTFTSKLIDGRFPDYEAVIPIGADREVRIEREILRASLQRAAILSNEKYRGVRIEVSPGQLKISAHNPEQEEAQEEVEADTKVDDLAVGFNVNYLLDALTALRDEHVVLALRDANSSALVREASNERCRHVVMPLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ37</accession>
    <name>A0A0S2DQ37_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC transporter substrate-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Toluene tolerance protein Ttg2D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ttg2D</name>
        <name evidence="4" type="ORF">D9T17_03530</name>
        <name evidence="3" type="ORF">FE772_25340</name>
        <name evidence="2" type="ORF">GLE_5236</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">OH11</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000011">
        <property type="protein sequence ID" value="ROU08561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949655.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000011.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5236"/>
    <dbReference type="EnsemblBacteria" id="ALN60577">
        <property type="protein sequence ID" value="ALN60577"/>
        <property type="gene ID" value="GLE_5236"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5236"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5154"/>
    <dbReference type="OMA" id="ISKSIMT"/>
    <dbReference type="OrthoDB" id="1716096at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008869">
        <property type="entry name" value="MlaC/ttg2D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042245">
        <property type="entry name" value="Tgt2/MlaC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36573">
        <property type="entry name" value="PTHR36573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05494">
        <property type="entry name" value="MlaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004649">
        <property type="entry name" value="MlaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242267" evidence="1">
        <location>
            <begin position="25"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROU08561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="220" mass="23437" checksum="282EDC6CBE1BDB75" modified="2016-02-17" version="1">MKRILTASVLACALLAGVPSLALAQATAAAGTAPAAGTPSAMVLGNTTRILSTLESRRAEFSKNRAALSQFVTTEFNQLFDRDYAARLVLGTHGRGAADADVALFSDALTSSLMQRYGSALLDFNTRLQVRIKSETPLRGGAIVKVSSEFLRQGGEPVPVDYLLRKTGNQWKVFDVMVEGVSFVQTFRNQFDAPLSQKSIAQVAADIKAGKLQAQASGNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ40</accession>
    <name>A0A0S2DQ40_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tetratricopeptide repeat domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5152</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949592.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5152"/>
    <dbReference type="EnsemblBacteria" id="ALN60493">
        <property type="protein sequence ID" value="ALN60493"/>
        <property type="gene ID" value="GLE_5152"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5152"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5075"/>
    <dbReference type="OMA" id="LWWDNAL"/>
    <dbReference type="OrthoDB" id="1303890at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="690" mass="75005" checksum="A6AAE14C92316E35" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ61</accession>
    <name>A0A0S2DQ61_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949748.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60702">
        <property type="protein sequence ID" value="ALN60702"/>
        <property type="gene ID" value="GLE_5361"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5361"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5276"/>
    <dbReference type="OrthoDB" id="2090402at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="286" mass="29652" checksum="01DA26FBD473FA1F" modified="2016-02-17" version="1">MSAAPAENRSPAFVPLALAVLMLALTAAFTAIAMRSLPALHGARFDPAQWLGSIGLPVGFVVVVACALTDRRGVPARPWACVLAALVLLFGLGLAWSMLEMPWLASLSRRADARALLAWTDGLGALKSLLVALVALPLAWRLGGRGATPVQWSPRQRRLLGALTALCLGAGVALLVQSLAAAFTALGDSEQRVGMSVVALGVGVVHGLVALIAPMRRGAGALPALVSALLTPVLIVLGSLPAMFGGEHWNLPARVIVVLVVLLLAPALSWLLVRRRLGAAARTDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ63</accession>
    <name>A0A0S2DQ63_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ATP-grasp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_5019</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949490.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5019"/>
    <dbReference type="EnsemblBacteria" id="ALN60360">
        <property type="protein sequence ID" value="ALN60360"/>
        <property type="gene ID" value="GLE_5019"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5019"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4947"/>
    <dbReference type="OMA" id="GYMSGWT"/>
    <dbReference type="OrthoDB" id="1677960at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041472">
        <property type="entry name" value="BL00235/CARNS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040570">
        <property type="entry name" value="LAL_C2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18130">
        <property type="entry name" value="ATPgrasp_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18603">
        <property type="entry name" value="LAL_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="122"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="425" mass="46627" checksum="E5975CEC929187D4" modified="2016-02-17" version="1">MAHLLMIESWVGGTGRIFPPAIARLGHRYTFVTRNRGHYQDPRSREIHPVIEHADNVLSFDTNDVPALVEFLRAQHEALEFDGVVTICDYYIGTVAEVAQALNLPQAFSDNVVMERRKDLVREAIERAFLPNPKFAVAGEWEPVRREAERIGYPLIVKPTDLASSAFVKLVRDEAQLRESFDALAAFPRNFREQERVPLLLLEEYMDGEEVSVEACTYRGETTVIGITDKSVTGFPYFIEDGHMFPARLEPQLAQEIEALVRGALAAVGHDHGLSHTEVKLTSKGPRIVEINPRPGGNYIAELIQRVTGIDLLDAQIELALGREPDLRRRDTGVASAAIRFLVPPRAGRALALDGAAALDADPRVARYSLAAVAGTDVSAPIDNACYLGHVVATDPDGPHARAHAERAVAGLTLRYADEAVAPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQD1</accession>
    <name>A0A0S2DQD1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein MgtC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FE772_24640</name>
        <name evidence="8" type="ORF">GLE_5083</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MgtC/SapB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949543.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5083"/>
    <dbReference type="EnsemblBacteria" id="ALN60424">
        <property type="protein sequence ID" value="ALN60424"/>
        <property type="gene ID" value="GLE_5083"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5083"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5010"/>
    <dbReference type="OMA" id="VIMREEG"/>
    <dbReference type="OrthoDB" id="2022224at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003416">
        <property type="entry name" value="MgtC/SapB/SrpB/YhiD_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33778">
        <property type="entry name" value="PTHR33778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02308">
        <property type="entry name" value="MgtC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01837">
        <property type="entry name" value="MGTCSAPBPROT"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN60424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW28362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="238" mass="25213" checksum="E7853B89A0AB3E11" modified="2016-02-17" version="1">MRFLHTFQLLPFLDTVASLLAAFVLGTLIGAERQYRQRTAGLRTNVLVAVGAAAFVDLGMRLAGSVEAVRVISYVVSGIGFLGAGVIMKEGMNVRGLNTAATLWCSAAVGACTGADMIAEGALLTAFVIAGNTLLRPLVNAINRVPIDERVSEATYEVRLSVAPESAPAAREWLVDHLEAANYPVGDVDVDEHGETATQIVAILVSTAVVAAELDAVVERLRRLPGVMHATWESSTRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQE5</accession>
    <name>A0A0S2DQE5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cell surface protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_04730</name>
        <name evidence="5" type="ORF">FE772_25585</name>
        <name evidence="3" type="ORF">GLE_5292</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000009">
        <property type="protein sequence ID" value="OPD65052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949695.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5292"/>
    <dbReference type="EnsemblBacteria" id="ALN60633">
        <property type="protein sequence ID" value="ALN60633"/>
        <property type="gene ID" value="GLE_5292"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65052">
        <property type="protein sequence ID" value="OPD65052"/>
        <property type="gene ID" value="BV903_04730"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5292"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5210"/>
    <dbReference type="OMA" id="MNAMGNI"/>
    <dbReference type="OrthoDB" id="1819071at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595576" evidence="2">
        <location>
            <begin position="21"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD65052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW28515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="253" mass="24865" checksum="A49B53DF68550BF5" modified="2016-02-17" version="1">MKAQLTLLALALAVAAPAYAEGDDARIHSDTSVSNRIHVGGHVGVRGKIRVASESAATVDQDQNAVGNSSLGDGDHDAHLGGSALSNAQGNIGANVAAGVGNAQSNDTALSAVDGQKVFASAMVFNDQKTAFNYATSSQQDTYYDATLDGSALSSAKGNIGVNVGAGVGNAQSNGMAASVNSSGTIAKAASDSEQHTWLNELAAACDLDTFATLAGSALSGAQGNIGANVAAGVGNAQHNGLSIATASCGSCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQJ6</accession>
    <name>A0A0S2DQJ6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RHS repeat protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Rhs family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_00840</name>
        <name evidence="3" type="ORF">GLE_5527</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949867.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5527"/>
    <dbReference type="EnsemblBacteria" id="ALN60868">
        <property type="protein sequence ID" value="ALN60868"/>
        <property type="gene ID" value="GLE_5527"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5527"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5443"/>
    <dbReference type="OMA" id="NEGDRWH"/>
    <dbReference type="OrthoDB" id="1639867at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045351">
        <property type="entry name" value="DUF6531"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031325">
        <property type="entry name" value="RHS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006530">
        <property type="entry name" value="YD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20148">
        <property type="entry name" value="DUF6531"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05593">
        <property type="entry name" value="RHS_repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01643">
        <property type="entry name" value="YD_repeat_2x"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726692" evidence="1">
        <location>
            <begin position="19"/>
            <end position="1566"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6531" evidence="2">
        <location>
            <begin position="222"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="1566" mass="170381" checksum="D8D4BAE2782F4A85" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DR63</accession>
    <name>A0A0S2DR63_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5536</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60877">
        <property type="protein sequence ID" value="ALN60877"/>
        <property type="gene ID" value="GLE_5536"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5536"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="40" mass="4284" checksum="26FC9A1A0E2993A8" modified="2016-02-17" version="1">MGATTTMLPSLISKHSTCPVISKWGRLMLPPPSVPASHPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-09-13" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>Q6BCG2</accession>
    <name>Q6BCG2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Beta-1,3-glucanase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Glucanase B</fullName>
            <ecNumber evidence="4">3.2.1.39</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gluB</name>
        <name evidence="5" type="ORF">FE772_07425</name>
        <name evidence="4" type="ORF">GLE_1403</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2004-06" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Reedy J.D."/>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">C3</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="journal article" date="2005" name="Phytopathology" volume="95" first="701" last="707">
            <title>Mutagenesis of beta-1,3-Glucanase Genes in Lysobacter enzymogenes Strain C3 Results in Reduced Biological Control Activity Toward Bipolaris Leaf Spot of Tall Fescue and Pythium Damping-Off of Sugar Beet.</title>
            <authorList>
                <person name="Palumbo J.D."/>
                <person name="Yuen G.Y."/>
                <person name="Jochum C.C."/>
                <person name="Tatum K."/>
                <person name="Kobayashi D.Y."/>
            </authorList>
            <dbReference type="PubMed" id="18943787"/>
            <dbReference type="DOI" id="10.1094/PHYTO-95-0701"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="3">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.39" evidence="4"/>
    <dbReference type="EMBL" id="AY667478">
        <property type="protein sequence ID" value="AAT77161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946751.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1403"/>
    <dbReference type="CAZy" id="GH64">
        <property type="family name" value="Glycoside Hydrolase Family 64"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56760">
        <property type="protein sequence ID" value="ALN56760"/>
        <property type="gene ID" value="GLE_1403"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1403"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1384"/>
    <dbReference type="OMA" id="SFQKPDA"/>
    <dbReference type="OrthoDB" id="552273at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.920.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037398">
        <property type="entry name" value="Glyco_hydro_64"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032477">
        <property type="entry name" value="Glyco_hydro_64_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042517">
        <property type="entry name" value="Glyco_hydro_64_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38165">
        <property type="entry name" value="PTHR38165"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16483">
        <property type="entry name" value="Glyco_hydro_64"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007707831" evidence="1">
        <location>
            <begin position="27"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_64" evidence="2">
        <location>
            <begin position="32"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AAT77161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="395" mass="42347" checksum="88A62A7152D92DFF" modified="2004-09-13" version="1">MVTRRTFLGASAAALAVPLLPRGALAATPARFNLALLNASGQNTAYAYVTGFDNGRPVFVRADGSAYYPPSPSAPVTPLGADCAIPLGANGSTVRVSVPRMYGARIYLVTGSKLNFYVNPGPAVVHPSFLNTSDTNFNKNWTFAEFTFNEYELFSNISYVDFVAAPLGLSLRSLSGRVETIPGLPAASLDPICYSLQQQATQEGSAWNSLIQRGPDGRNLRAMSAHYQAARFQNYLTGYIDACWNKYRGTTLTVDTQSGFGVLTARVGGDNLLRFNNGEAFAKPSTADVLSCDSGPFSLGGASDVRKAIIPRLAAALNRTTLLDNANQPNGEVASRFYRNAQTNHYARLVHERLPDNRGYAFPYDDVTASGGPDFSGAARSGDPDTLTVTLRALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA65</accession>
    <name>A0A0S2DA65_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0074</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55433">
        <property type="protein sequence ID" value="ALN55433"/>
        <property type="gene ID" value="GLE_0074"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0074"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.79"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="55" mass="6193" checksum="94F474E02F1AD53C" modified="2016-02-17" version="1">MVSDVTNAATNRRFFLRDESLTKSLVSACAHKRDAAQNLLFPRPQANCRIAQFVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAM9</accession>
    <name>A0A0S2DAM9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Deoxyuridine 5'-triphosphate nucleotidohydrolase</fullName>
            <shortName evidence="4">dUTPase</shortName>
            <ecNumber evidence="4">3.6.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">dUTP pyrophosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">dut</name>
        <name evidence="7" type="ORF">BV903_12965</name>
        <name evidence="8" type="ORF">FE772_02090</name>
        <name evidence="6" type="ORF">GLE_0253</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">C3</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>dUTP + H2O = diphosphate + dUMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10248"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61555"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="3.6.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the dUTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.23" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000032">
        <property type="protein sequence ID" value="OPD63530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945904.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0253"/>
    <dbReference type="EnsemblBacteria" id="ALN55612">
        <property type="protein sequence ID" value="ALN55612"/>
        <property type="gene ID" value="GLE_0253"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63530">
        <property type="protein sequence ID" value="OPD63530"/>
        <property type="gene ID" value="BV903_12965"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0253"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.255"/>
    <dbReference type="OMA" id="YAAFVHP"/>
    <dbReference type="OrthoDB" id="1669228at2"/>
    <dbReference type="UniPathway" id="UPA00610">
        <property type="reaction ID" value="UER00666"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004170">
        <property type="term" value="F:dUTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006226">
        <property type="term" value="P:dUMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046081">
        <property type="term" value="P:dUTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00116">
        <property type="entry name" value="dUTPase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008181">
        <property type="entry name" value="dUTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11241">
        <property type="entry name" value="PTHR11241"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="SSF51283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00576">
        <property type="entry name" value="dut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="dUTPase" evidence="5">
        <location>
            <begin position="17"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="71"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="88"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN55612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD63530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW24646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="152" mass="15941" checksum="E97119BA4C97AD00" modified="2016-02-17" version="1">MHHTLELKILDPRFGGEWPLPAYATPASAGLDLRAALEQPLTLQPGDAALLPSGLAVHVGDPAMCAVVLPRSGLGHKHGIVLGNGTGLIDADYQGPLLISVWNRGSEAYTIQPGDRVAQLVVLPIVRASLQVVSEFQASERGEGGFGHTGVR</sequence>
</entry>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="57" mass="6008" checksum="0EC3BB9BD77CD7BC" modified="2016-02-17" version="1">MSHLRTRRARALLLAVLFATGIGFGAVHADTKYAEGCALKSGCQFGGTRFGCCVDDS</sequence>
</entry>
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    <name>A0A0S2DB66_LYSEN</name>
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        <submittedName>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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            <begin position="541"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="677" mass="74638" checksum="609CAC169C4D4579" modified="2016-02-17" version="1"> </sequence>
</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="328" mass="35712" checksum="490C8FD645C5D991" modified="2016-02-17" version="1">MAAAETMASMSYFGKLPSRGDFVRTAESHQLMVLLDRWAGSGVELLAQDPGWKQLYDTAPPMHFAFLGSRSRLAIGGHFLPSRDATERRFPFLSATYLDISQPLAFIGRSPLVLARVWGGLARLCGQAVRAEDAADSLRELSENKVAVTTDPGVYDAPFADFLDMQDVGALQSLLHQSGHAHVQLRWVLPALGLLLQPVLTGAASQIDKALSLPLPRDALYRPMVAAFWLDLVSGFLSRADFELAVMIQETAAPRLVIGFNGADGRTLQAVLDPHVGGEQIIRVDDAEWVDNHVAGDYALNKLVSYIGRDDLSLRVARKAFGETFLGA</sequence>
</entry>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="38" mass="3725" checksum="7E0F3373C142DDFC" modified="2016-02-17" version="1">MGLTAAERPVPGALRAAYWEDASQPSANAIAAIAAAAA</sequence>
</entry>
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    <accession>A0A0S2DBG2</accession>
    <name>A0A0S2DBG2_LYSEN</name>
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        </submittedName>
    </protein>
    <gene>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="8"/>
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        </location>
    </feature>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC00</accession>
    <name>A0A0S2DC00_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP synthase subunit c</fullName>
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        <alternativeName>
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        </alternativeName>
        <alternativeName>
            <fullName evidence="13">F-type ATPase subunit c</fullName>
            <shortName evidence="13">F-ATPase subunit c</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Lipid-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
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        <name evidence="18" type="ORF">FE772_04105</name>
        <name evidence="15" type="ORF">GLE_0684</name>
        <name evidence="16" type="ORF">LEN_4263</name>
        <name evidence="20" type="ORF">SAMN05421681_11522</name>
    </gene>
    <organism evidence="15 21">
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        <lineage>
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            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="15 21" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 21">C3</strain>
        </source>
    </reference>
    <reference evidence="24" key="2">
        <citation type="journal article" date="2016" name="DNA Res." volume="0" first="0" last="0">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer, Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24">M497-1</strain>
        </source>
    </reference>
    <reference evidence="20 22" key="3">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 22">ATCC 29487</strain>
        </source>
    </reference>
    <reference evidence="16 24" key="4">
        <citation type="journal article" date="2017" name="DNA Res." volume="24" first="169" last="177">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
            <dbReference type="PubMed" id="28065880"/>
            <dbReference type="DOI" id=".1093/dnares/dsw055"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 24">M497-1</strain>
        </source>
    </reference>
    <reference evidence="17 23" key="5">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 23">B25</strain>
        </source>
    </reference>
    <reference evidence="19 25" key="6">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 25">OH11</strain>
        </source>
    </reference>
    <reference evidence="18 26" key="7">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 26">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="function">
        <text evidence="13">Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the ATPase C chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP014940">
        <property type="protein sequence ID" value="BAV99750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000017">
        <property type="protein sequence ID" value="OPD64429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000061">
        <property type="protein sequence ID" value="ROU04433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNOG01000015">
        <property type="protein sequence ID" value="SDY25478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946213.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000061.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0684"/>
    <dbReference type="EnsemblBacteria" id="ALN56042">
        <property type="protein sequence ID" value="ALN56042"/>
        <property type="gene ID" value="GLE_0684"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAV99750">
        <property type="protein sequence ID" value="BAV99750"/>
        <property type="gene ID" value="LEN_4263"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64429">
        <property type="protein sequence ID" value="OPD64429"/>
        <property type="gene ID" value="BV903_08395"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY25478">
        <property type="protein sequence ID" value="SDY25478"/>
        <property type="gene ID" value="SAMN05421681_11522"/>
    </dbReference>
    <dbReference type="KEGG" id="lem:LEN_4263"/>
    <dbReference type="KEGG" id="lez:GLE_0684"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.672"/>
    <dbReference type="OMA" id="QPELMNE"/>
    <dbReference type="OrthoDB" id="2078221at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000183696">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000218824">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01396">
        <property type="entry name" value="ATP_synth_c_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005953">
        <property type="entry name" value="ATP_synth_csu_bac/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000454">
        <property type="entry name" value="ATP_synth_F0_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020537">
        <property type="entry name" value="ATP_synth_F0_csu_DDCD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038662">
        <property type="entry name" value="ATP_synth_F0_csu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00124">
        <property type="entry name" value="ATPASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="SSF81333"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01260">
        <property type="entry name" value="ATP_synt_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00605">
        <property type="entry name" value="ATPASE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 13" id="KW-0138">CF(0)</keyword>
    <keyword evidence="6 13" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_C" evidence="14">
        <location>
            <begin position="13"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="site" description="Reversibly protonated during proton transport" evidence="13">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ALN56042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="BAV99750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OPD64429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="QCW24975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ROU04433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="SDY25478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000183696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000218824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="93" mass="9285" checksum="8E96532FBDE21151" modified="2016-02-17" version="1">MEFIANVQGLTAIAIGIMVGLGAIGACLGIALMGSKFLESAARQPELVPMLQGRMFLLAGLIDAAFIIALAVGLLFAFGNPLLGALQAAGAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC24</accession>
    <name>A0A0S2DC24_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="13">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLE_0715</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946243.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0715"/>
    <dbReference type="EnsemblBacteria" id="ALN56073">
        <property type="protein sequence ID" value="ALN56073"/>
        <property type="gene ID" value="GLE_0715"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0715"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.703"/>
    <dbReference type="OMA" id="SYELQWR"/>
    <dbReference type="OrthoDB" id="71288at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015420">
        <property type="term" value="F:ABC-type vitamin B12 transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010101">
        <property type="entry name" value="B12_transptr_BtuB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01779">
        <property type="entry name" value="TonB-B12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0626">Porin</keyword>
    <keyword evidence="13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="5 9" id="KW-0798">TonB box</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595294" evidence="10">
        <location>
            <begin position="24"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="12">
        <location>
            <begin position="47"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="11">
        <location>
            <begin position="178"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN56073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="616" mass="67676" checksum="FB229A0E74257511" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC41</accession>
    <name>A0A0S2DC41_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Surface layer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_04405</name>
        <name evidence="1" type="ORF">GLE_0744</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946266.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56102">
        <property type="protein sequence ID" value="ALN56102"/>
        <property type="gene ID" value="GLE_0744"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0744"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.732"/>
    <dbReference type="OMA" id="KEMRHYA"/>
    <dbReference type="OrthoDB" id="1970512at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="91" mass="10429" checksum="1C1A049FCDC9EB62" modified="2016-02-17" version="1">MSADTKTPLDHVNTTLNQLKEMRHYAKNYVEQLTGQWLLFDGELKKLKQAQRIEELMVRQGELYEALDKEIAELEELATSLQPAPEDAAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCB2</accession>
    <name>A0A0S2DCB2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0802</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56160">
        <property type="protein sequence ID" value="ALN56160"/>
        <property type="gene ID" value="GLE_0802"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0802"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.791"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="70" mass="8057" checksum="90C46F80078CD08E" modified="2016-02-17" version="1">MDMDMDMDVGAGGVAIRRRQTMVAVPMPRFRPNPRRPIPRRPFIARRATGHASAPDDALRSRHRRPQRIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCH0</accession>
    <name>A0A0S2DCH0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Pyrophosphate--fructose 6-phosphate 1-phosphotransferase</fullName>
            <ecNumber evidence="10">2.7.1.90</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">6-phosphofructokinase, pyrophosphate dependent</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">PPi-dependent phosphofructokinase</fullName>
            <shortName evidence="10">PPi-PFK</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Pyrophosphate-dependent 6-phosphofructose-1-kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">pfkA</name>
        <name evidence="10" type="synonym">pfp</name>
        <name evidence="13" type="ORF">FE772_04945</name>
        <name evidence="12" type="ORF">GLE_0856</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">C3</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 10">Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6-bisphosphate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13613"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="EC" id="2.7.1.90"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="10">Non-allosteric.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 10">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.90" evidence="10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946348.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0856"/>
    <dbReference type="EnsemblBacteria" id="ALN56214">
        <property type="protein sequence ID" value="ALN56214"/>
        <property type="gene ID" value="GLE_0856"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0856"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.845"/>
    <dbReference type="OMA" id="AHDIGYF"/>
    <dbReference type="OrthoDB" id="1421302at2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047334">
        <property type="term" value="F:diphosphate-fructose-6-phosphate 1-phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01978">
        <property type="entry name" value="Phosphofructokinase_II_B2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011404">
        <property type="entry name" value="PPi-PFK_XF0274"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036483">
        <property type="entry name" value="PFK_XF0274"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="SSF53784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 10 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PFK" evidence="11">
        <location>
            <begin position="22"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="151"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="199"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="307"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity and substrate specificity; stabilizes the transition state when the phosphoryl donor is PPi; prevents ATP from binding by mimicking the alpha-phosphate group of ATP" evidence="10">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity; stabilizes the transition state when the phosphoryl donor is PPi" evidence="10">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN56214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW25117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="430" mass="45459" checksum="F10DF8C7A771D181" modified="2016-02-17" version="1">MPTAKTARKSAGKPAGNLLYAQSGGVTAVINATAAGVIEAARARKVRVLAARNGILGALREELIDTSKESAAAIRALGHTPGGAFGSCRLKLKALDADRARYERLLAVLQAHDVRWFLYNGGNDSADTALKVSQLAAEYGYPLTCVGVPKTVDNDLAVTDCCPGFGSAAKYTAVSVREAALDVAAMAETSTKVFVYEAMGRHAGWLAAAAGLAGADADAAPHLILFPERPFEEADFFAKVKATVERVGYCVVVASEGIQTADGRFVADAGGGKDSFGHTQLGGVASHLAGRVKDALGYKVHWALPDYLQRSARHLASKTDVEQARAVGKAAVEYALKGMNSVMPAIVRSSDAPYRWKIEPVPLSKVANHEKKMPANFIRKDGYGITAAARKYLEPLIRGEAPPPYGRDGLPQYVTLKNVAVKAKLPPFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCI3</accession>
    <name>A0A0S2DCI3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EVE domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_19620</name>
        <name evidence="4" type="ORF">FE772_05080</name>
        <name evidence="2" type="ORF">GLE_0883</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000057">
        <property type="protein sequence ID" value="OPD62203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946367.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000057.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0883"/>
    <dbReference type="EnsemblBacteria" id="ALN56241">
        <property type="protein sequence ID" value="ALN56241"/>
        <property type="gene ID" value="GLE_0883"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62203">
        <property type="protein sequence ID" value="OPD62203"/>
        <property type="gene ID" value="BV903_19620"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0883"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.872"/>
    <dbReference type="OMA" id="LWDGIRN"/>
    <dbReference type="OrthoDB" id="1829674at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002740">
        <property type="entry name" value="EVE_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01878">
        <property type="entry name" value="EVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EVE" evidence="1">
        <location>
            <begin position="6"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="156" mass="17919" checksum="AA9AAE80DCEFF6D4" modified="2016-02-17" version="1">MTARRRYWLMKSEPDTFSIDDLERVRTEPWNGVRNYQARNYMRDGMKVGDGVLFYHSNTAVPGIVGIATIAAEAYPDPTQFDPKSDYHDPKSTREDPRWLLVDVAFERKLSRTIALDEIKARADELGEDFALTRRGNRLSVLPVSAAQWKLLLAME</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCP9</accession>
    <name>A0A0S2DCP9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Dicarboxylate/amino acid:cation symporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Transporter, dicarboxylate/amino acid:cation (Na+ or H+) symporter (DAACS) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BV903_12345</name>
        <name evidence="9" type="ORF">FE772_05355</name>
        <name evidence="7" type="ORF">GLE_0944</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000030">
        <property type="protein sequence ID" value="OPD63610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946414.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000030.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0944"/>
    <dbReference type="EnsemblBacteria" id="ALN56302">
        <property type="protein sequence ID" value="ALN56302"/>
        <property type="gene ID" value="GLE_0944"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63610">
        <property type="protein sequence ID" value="OPD63610"/>
        <property type="gene ID" value="BV903_12345"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0944"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.932"/>
    <dbReference type="OMA" id="ICSFVVP"/>
    <dbReference type="OrthoDB" id="781228at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865">
        <property type="entry name" value="PTHR42865"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="SSF118215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN56302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD63610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW25173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="454" mass="47839" checksum="1C326D663D1CB5E7" modified="2016-02-17" version="1">MSETQNARKQLPLHWKMAIGFLAGLGLGLIVYAAGVGGISWAQLTGQACEAGATGWRCESLLKLFTEVITGPAGEIFLRLIFMLVIPLLFSALVMGVSEMGDIRAFGRVGWRTLGLTIVMSGLAVVLGLVMVNVFQPGAGMDPAQAQQLMSENAERAQSIVKGSADAPKGIQMLVSIVPSNVVQAAADDAILAVMFFALMIGVGMVLTKSKAVDTLRDGIQGLFEISMTLIGLVIKLAPYAVFCFMFNLSSQFGWDLLFKLAKYVAVVVAALAIHLFVVYSLAIKFVGGRSPLAFFKGAQEAMVLAFSTASSNATLPTALRVADELKLPRRISRFVLTVGATANQNGTALFEGVTVIFLAQFFGVDLTLGQQVMVMLVCILGGIGTAGVPSGSLPVVAMICAMVKVPPEGIGLILGVNHFLDMCRTTLNVTGDIAIASMVSRGVEDPPAETLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCW9</accession>
    <name>A0A0S2DCW9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter, ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_0953</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946419.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0953"/>
    <dbReference type="EnsemblBacteria" id="ALN56311">
        <property type="protein sequence ID" value="ALN56311"/>
        <property type="gene ID" value="GLE_0953"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0953"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.940"/>
    <dbReference type="OMA" id="HPPVYAP"/>
    <dbReference type="OrthoDB" id="1200451at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="12"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="45"/>
            <end position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="221" mass="24701" checksum="89786478CB2E2A83" modified="2016-02-17" version="1">MNAAVSAAENTGFDIDIELRRGDARSGFRRAFAIRSEHRVIAVVGDSGAGKTSLLHAIAGLLRPVRGRIVVAGETLFDRERRIDLPAHRRRIGYVFQDARLFPHLDVRANLLYGLRGAGARERRFELDAIVELLGIGHLLARGTAGLSGGEMQRVALGRALLSQPRILLLDEPLSMLDMNRRDELLPYLQRVREESGLPMIYVSHYPEEVRRIAEDVHRIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD01</accession>
    <name>A0A0S2DD01_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1043</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1043"/>
    <dbReference type="EnsemblBacteria" id="ALN56401">
        <property type="protein sequence ID" value="ALN56401"/>
        <property type="gene ID" value="GLE_1043"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1043"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1031"/>
    <dbReference type="OMA" id="KSLMIEF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045746">
        <property type="entry name" value="ACT14924-like_Acyltransf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19576">
        <property type="entry name" value="Acyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="2">
        <location>
            <begin position="83"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="560"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="592" mass="65159" checksum="22FAFEC226D95605" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD16</accession>
    <name>A0A0S2DD16_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent outer membrane receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLE_1062</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1062"/>
    <dbReference type="EnsemblBacteria" id="ALN56420">
        <property type="protein sequence ID" value="ALN56420"/>
        <property type="gene ID" value="GLE_1062"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1062"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1051"/>
    <dbReference type="OMA" id="QYARGFR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015232">
        <property type="term" value="F:heme transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011276">
        <property type="entry name" value="TonB_haem/Hb_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010949">
        <property type="entry name" value="TonB_Hb/transfer/lactofer_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01785">
        <property type="entry name" value="TonB-hemin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01786">
        <property type="entry name" value="TonB-hemlactrns"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594948" evidence="6">
        <location>
            <begin position="39"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="66"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="7">
        <location>
            <begin position="295"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="771" mass="83771" checksum="F7A81457B78BF150" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDA4</accession>
    <name>A0A0S2DDA4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CBS domain protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">CBS domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_04080</name>
        <name evidence="6" type="ORF">D9T17_21520</name>
        <name evidence="5" type="ORF">FE772_06100</name>
        <name evidence="3" type="ORF">GLE_1111</name>
    </gene>
    <organism evidence="3 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">C3</strain>
        </source>
    </reference>
    <reference evidence="4 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">OH11</strain>
        </source>
    </reference>
    <reference evidence="5 10" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 10">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000007">
        <property type="protein sequence ID" value="OPD65299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000055">
        <property type="protein sequence ID" value="ROU04714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949983.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000055.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1111"/>
    <dbReference type="EnsemblBacteria" id="ALN56469">
        <property type="protein sequence ID" value="ALN56469"/>
        <property type="gene ID" value="GLE_1111"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65299">
        <property type="protein sequence ID" value="OPD65299"/>
        <property type="gene ID" value="BV903_04080"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1111"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1098"/>
    <dbReference type="OMA" id="APIKVYM"/>
    <dbReference type="OrthoDB" id="2014094at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04623">
        <property type="entry name" value="CBS_pair_bac_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044725">
        <property type="entry name" value="CBSX3_CBS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="9"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="76"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD65299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROU04714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="142" mass="15527" checksum="A47B119436C808C0" modified="2016-02-17" version="1">MRTVRQLLETKAPEVIAIGPDAPVIDAIRLMAEKRIGAVLVMDGARLAGILSERDYARKIVLQGRSSADTPVRDIMTAQVISVGLGDTAERCMQLVTDKRIRHLPVLEDGQVVGVVSIGDLVKAVIEDQRVELDQLQRYIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDD4</accession>
    <name>A0A0S2DDD4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ATP-grasp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1171</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946570.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1171"/>
    <dbReference type="EnsemblBacteria" id="ALN56529">
        <property type="protein sequence ID" value="ALN56529"/>
        <property type="gene ID" value="GLE_1171"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1171"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1156"/>
    <dbReference type="OMA" id="WEFIQFV"/>
    <dbReference type="OrthoDB" id="1677960at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="119"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="386" mass="41721" checksum="3DD244BA8D8DC6EF" modified="2016-02-17" version="1">MPNVLVLGARAPAALEIARRFRRDGRATAMVADSVSCRLSGWSNAVGASEPIAGPRFDAARFAADLARIVAQRRIDLVVPTCEEAFWLSRYRGALPVGVRVLVDEFDKLRELHSKLRFLELARGCGANVPDSAEVSDLEQARAWAAGRPLVLKPEYSRFGVHVRLYPQGMPADAAPLPLAQAWVAQRFHAGTELCSYSVADRGRLLAHSVYRPAYRLSRSSSFYFEPAPNATIRGFVERFVAKIGYTGQISFDWIVGDDGSATVLECNPRATSGVHLFGAGDDLPAALLGADIACVDARPARPRMLAPVMLGAGLAQALAQGRARAWLRDWRRADDVLAVPGDRLPPLGGLADLGAYAASALRRGGGLREAATRDIEWDGEELPDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDE1</accession>
    <name>A0A0S2DDE1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphotransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1228</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946614.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1228"/>
    <dbReference type="EnsemblBacteria" id="ALN56585">
        <property type="protein sequence ID" value="ALN56585"/>
        <property type="gene ID" value="GLE_1228"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1228"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1213"/>
    <dbReference type="OMA" id="HSRNLMV"/>
    <dbReference type="OrthoDB" id="1603998at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="37"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="341" mass="38725" checksum="B3D84E2D7251B2AD" modified="2016-02-17" version="1">MTQPHPSDRDAARLAWARAATGDDRLDLVRASFDAGFRSYWRGRVHAGAARPEGEVIVMDSPPELEDPRPWLRLREVLEAGGVRVPQVYRADPDQGFLLLEDLGRETVLQAVEAGRADADAMFDAAFGQLLKIQALPCPDDLPPYDEAFLTRELRLFDEWFLGRHLGATLDCGDLERLDLAYRRILDNVLAQRQVFIHRDFMPRNLMPIADGLAVIDFQGALRGPIAYDPISLFRDAFVSWPEERVETWLARYHARAVAAGIALPDYPRFRRDADFAGLQRHIKILGLFARLHHRDGKPKYLADAPRFLGYLDLVLPRYPELQPLSEIVERYVRPALAARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDR8</accession>
    <name>A0A0S2DDR8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dihydrofolate synthase/folylpolyglutamate synthase</fullName>
            <ecNumber evidence="6">6.3.2.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Folylpolyglutamate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">folC</name>
        <name evidence="15" type="ORF">GLE_1336</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n) + ATP + L-glutamate = (6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n+1) + ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:51912"/>
            <dbReference type="Rhea" id="RHEA-COMP:13257"/>
            <dbReference type="Rhea" id="RHEA-COMP:13258"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:136572"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>10-formyltetrahydrofolyl-(gamma-L-Glu)(n) + ATP + L-glutamate = 10-formyltetrahydrofolyl-(gamma-L-Glu)(n+1) + ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:51904"/>
            <dbReference type="Rhea" id="RHEA-COMP:13088"/>
            <dbReference type="Rhea" id="RHEA-COMP:14300"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:134413"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>7,8-dihydropteroate + ATP + L-glutamate = 7,8-dihydrofolate + ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:23584"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17839"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57451"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 7,8-dihydrofolate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the folylpolyglutamate synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.12" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946696.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1336"/>
    <dbReference type="EnsemblBacteria" id="ALN56693">
        <property type="protein sequence ID" value="ALN56693"/>
        <property type="gene ID" value="GLE_1336"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1336"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1318"/>
    <dbReference type="OMA" id="YFEMGTL"/>
    <dbReference type="OrthoDB" id="1232874at2"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00157"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008841">
        <property type="term" value="F:dihydrofolate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="PTHR11136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001563">
        <property type="entry name" value="Folylpolyglu_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01012">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="13 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="14">
        <location>
            <begin position="47"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00000809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00002714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00019357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR001563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ALN56693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="421" mass="44510" checksum="5AFF74C7EB0D03F2" modified="2016-02-17" version="1">MQTRSLADWLSYIERIHPKSIDMGLERIREVSKRLGLTRPGREVITVGGTNGKGSTVAFIEAIARADGRRVGAYTSPHLLAYNERIRIDGADAADADIVAAFEAIEAARGEVALTYFEYGTLAALWLFERAGLDLTILEVGLGGRLDATNIVDADVAVITTVDLDHQDYLGDDRESIGFEKAGIARGFKPLVLGDDDPPSSVLRHAYLIGASAVRAGCDFFFAPAPDDEASWNWREVGFEVELPRPALSAPVQMRNAAVAIAALRALDTAPSDEALARGVAQARVAGRLQRFERGGTEILVDVGHNPQAARELAAWLDAQPPRPTRAVFAALGDKDAVGVVAALGARIAAWHLAGLSGPRGVSVEAFAERLRGGAAEAGQRHASVAEALAAARAAAGEGERILVFGSFHTAAEALQALADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDW5</accession>
    <name>A0A0S2DDW5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 10">D-3-phosphoglycerate dehydrogenase</fullName>
            <ecNumber evidence="10">1.1.1.95</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">serA</name>
        <name evidence="13" type="ORF">BV903_24535</name>
        <name evidence="14" type="ORF">FE772_07110</name>
        <name evidence="12" type="ORF">GLE_1332</name>
    </gene>
    <organism evidence="12 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">C3</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">B25</strain>
        </source>
    </reference>
    <reference evidence="14 17" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 10">
            <text>(2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:12641"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="EC" id="1.1.1.95"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:49612"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.399"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 10">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 10">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.95" evidence="10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000095">
        <property type="protein sequence ID" value="OPD61290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946694.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000095.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1332"/>
    <dbReference type="EnsemblBacteria" id="ALN56689">
        <property type="protein sequence ID" value="ALN56689"/>
        <property type="gene ID" value="GLE_1332"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61290">
        <property type="protein sequence ID" value="OPD61290"/>
        <property type="gene ID" value="BV903_24535"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1332"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1314"/>
    <dbReference type="OMA" id="NIAGMQV"/>
    <dbReference type="OrthoDB" id="1638924at2"/>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00196"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004617">
        <property type="term" value="F:phosphoglycerate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029009">
        <property type="entry name" value="ASB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006236">
        <property type="entry name" value="PGDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045626">
        <property type="entry name" value="PGDH_ASB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19304">
        <property type="entry name" value="PGDH_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143548">
        <property type="entry name" value="SSF143548"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01327">
        <property type="entry name" value="PGDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0520">NAD</keyword>
    <keyword evidence="7 10 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 10" id="KW-0718">Serine biosynthesis</keyword>
    <feature type="domain" description="ACT" evidence="11">
        <location>
            <begin position="451"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN56689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OPD61290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW25467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="520" mass="53819" checksum="D4CC0111D84ABBF2" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDZ1</accession>
    <name>A0A0S2DDZ1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alkaline phosphatase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Intestinal alkaline phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_07580</name>
        <name evidence="4" type="ORF">GLE_1439</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the alkaline phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.1" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946775.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1439"/>
    <dbReference type="EnsemblBacteria" id="ALN56796">
        <property type="protein sequence ID" value="ALN56796"/>
        <property type="gene ID" value="GLE_1439"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1439"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1419"/>
    <dbReference type="OMA" id="DNFYTIA"/>
    <dbReference type="OrthoDB" id="585847at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16012">
        <property type="entry name" value="ALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001952">
        <property type="entry name" value="Alkaline_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596">
        <property type="entry name" value="PTHR11596"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00245">
        <property type="entry name" value="Alk_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00113">
        <property type="entry name" value="ALKPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00098">
        <property type="entry name" value="alkPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242289" evidence="3">
        <location>
            <begin position="23"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="408"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="436"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="568" mass="60466" checksum="CFD3C83AD965E907" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE65</accession>
    <name>A0A0S2DE65_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1479</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56836">
        <property type="protein sequence ID" value="ALN56836"/>
        <property type="gene ID" value="GLE_1479"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1479"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1460"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="133" mass="14457" checksum="236738D1F9D60C2B" modified="2016-02-17" version="1">MVIAILRVAVGLALVWVGISWAVLSMVPIDEGETFGWRSLGVFTLVVAAIGFMSGLISGRYLLVPALLLSTVGWLLLINVLQWPEIKGGTGTFMSGVIERAPQVLWCNACLALGTSMGYRLARRWKWVAPARN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEF9</accession>
    <name>A0A0S2DEF9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA-binding S4 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_07350</name>
        <name evidence="1" type="ORF">GLE_1387</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
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    <dbReference type="EnsemblBacteria" id="ALN56744">
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    <dbReference type="KEGG" id="lez:GLE_1387"/>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="74" mass="7801" checksum="C4011EE98F92DA8E" modified="2016-02-17" version="1">MQPIRFALDAGHDYVELNQLLKLAGLAHSGGTGKAIVASGAVRVDGQVELRKTCKIRAGQVVECEGVRIEVAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF20</accession>
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        <submittedName>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">B25</strain>
        </source>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
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    </evidence>
    <sequence length="611" mass="66807" checksum="118F471BD181CB5E" modified="2016-02-17" version="1"> </sequence>
</entry>
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    <accession>A0A0S2DF41</accession>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">B25</strain>
        </source>
    </reference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_1584"/>
    <dbReference type="EnsemblBacteria" id="ALN56941">
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    </dbReference>
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        <property type="gene ID" value="BV903_12685"/>
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    </dbReference>
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        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
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        <property type="project" value="UniProtKB-EC"/>
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            <end position="266"/>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="OPD63571.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
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</entry>
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        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">C3</strain>
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    </reference>
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    </dbReference>
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        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF92</accession>
    <name>A0A0S2DF92_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1849</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947094.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1849"/>
    <dbReference type="EnsemblBacteria" id="ALN57201">
        <property type="protein sequence ID" value="ALN57201"/>
        <property type="gene ID" value="GLE_1849"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1849"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1820"/>
    <dbReference type="OMA" id="TWRHRTY"/>
    <dbReference type="OrthoDB" id="324612at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="358" mass="37666" checksum="67AD8733246CB229" modified="2016-02-17" version="1">MPSSNPSAGSGDLPSDIDVVVIGAGQAGLAVGHTLKQAGVDFVMLDAASELGVSWTNRWDSLRLFTSAQFSGLPGLPFPGDPDRYPAKDEVPDYFRTYAATFALPIHLGTPVTSVGRSGEGFSVTTPAGRIAARQVVAAVGAFQTPAVPGFSQRLAPSVAQLHSHAYRNPGQIPAGPVAVVGSANSGLQIAAELSATHEVVVCKGRRQPRLPQRILGKDAFWWLSKSGILRLPTNTPLARRLAMPDPIVDTKSGGPARSVRYAARAVDAAGTQLVTADGQRLDVSTVLWATGYRNEWPWLDAELLGADGQPPHDAGVGASGLHFVGLYRMRNRGSALLGFVGRDAQRVGAAVARRSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFD8</accession>
    <name>A0A0S2DFD8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transglutaminase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1681</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946973.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1681"/>
    <dbReference type="EnsemblBacteria" id="ALN57037">
        <property type="protein sequence ID" value="ALN57037"/>
        <property type="gene ID" value="GLE_1681"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1681"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1659"/>
    <dbReference type="OMA" id="QFDAHAW"/>
    <dbReference type="OrthoDB" id="670657at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025403">
        <property type="entry name" value="DUF4129"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021878">
        <property type="entry name" value="TgpA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13559">
        <property type="entry name" value="DUF4129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11992">
        <property type="entry name" value="TgpA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="552"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="TGc" evidence="2">
        <location>
            <begin position="410"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="668" mass="74140" checksum="38323E581727DE1D" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFH6</accession>
    <name>A0A0S2DFH6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Acetyl-CoA acetyltransferase</fullName>
            <ecNumber evidence="8">2.3.1.9</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Thiolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FE772_10020</name>
        <name evidence="8" type="ORF">GLE_1971</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.9" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947179.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1971"/>
    <dbReference type="EnsemblBacteria" id="ALN57321">
        <property type="protein sequence ID" value="ALN57321"/>
        <property type="gene ID" value="GLE_1971"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1971"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1936"/>
    <dbReference type="OMA" id="TNVCCTT"/>
    <dbReference type="OrthoDB" id="1058688at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003985">
        <property type="term" value="F:acetyl-CoA C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="6">
        <location>
            <begin position="4"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="7">
        <location>
            <begin position="268"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="4">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="347"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN57321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW25951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="391" mass="39657" checksum="3531AC60A87047EF" modified="2016-02-17" version="1">MSDVVIVGAKRTAIGSFLGQFTGVPTPTLGSAAIAGALEQAGVAADQVDEVIMGCVLPAGLGQAPARQAALGAGLPTAAGCTTINKVCGSGMKAIMLAHDLIQAGSAKVVVAGGMESMTNAPHLLNNSRTGIRYGSAEFLDHMAWDGLTNPYDGKAMGVFGDAACAKYGYDRAAIDAYSEESVKRAQAAQSSGHFKDEIVSVTVKGRKGDVVVDADEEPAKIDVAKIPTLRPAFGKDGVLTAAASSKISDGAAATALMSADEAAARGLKPLARIVAHASHAQAPEWFTTAPVKAISNVLEKAGWKVGDVDLFEVNEAFSVVAMAPMTELGIAHDKLNVHGGAVALGHPIGASGARLVVTLINALRIRGGKRGVASLCIGGGEATAIAIELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFI5</accession>
    <name>A0A0S2DFI5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Histidinol-phosphate aminotransferase</fullName>
            <ecNumber evidence="6">2.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Imidazole acetol-phosphate transaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hisC</name>
        <name evidence="8" type="ORF">GLE_1899</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>2-oxoglutarate + L-histidinol phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23744"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="2.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.9" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947128.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1899"/>
    <dbReference type="EnsemblBacteria" id="ALN57250">
        <property type="protein sequence ID" value="ALN57250"/>
        <property type="gene ID" value="GLE_1899"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1899"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1867"/>
    <dbReference type="OMA" id="IWLNANE"/>
    <dbReference type="OrthoDB" id="1248286at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00012"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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            <begin position="48"/>
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        <location>
            <position position="221"/>
        </location>
    </feature>
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        <source>
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        </source>
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        <source>
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        <source>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN57250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="374" mass="39673" checksum="A7827085DEADC1D4" modified="2016-02-17" version="1">MSQTRDDNPLDLLREDLRDFAGYKSARSDKRSGRVWLNANEAAWPSVADCDGAVRRYPDPQPPALRDALARLYGCAPEQLLAGRGSDEGIDLLVRAFCRPGGDAIVIAPPTFGMYAVSARLHGARVVEVPLRDCAEGFVCDFDALAEAAEREAAKLVFVCSPGNPSGTLLPLASIDALAQRLSGRAIVVVDEAYIEFADGESAVSLLRRRRNVAVLRTLSKAHALAAARIGSTIADAGVVAALQRCQAPYPLPTPCVNLTLRALGEVPGNTTKARVATAMCERDTLFQALQGLPGVRRVYPSQANFLLLRFDDAQAALDALLDAGVVVRDFRHAPGLDDALRISLGTPEQNAAVIEVLGRALRASAAVATGAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFR9</accession>
    <name>A0A0S2DFR9_LYSEN</name>
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    </protein>
    <gene>
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            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">C3</strain>
        </source>
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        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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            <begin position="75"/>
            <end position="228"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="228" mass="24775" checksum="F732C5CFF690DE4F" modified="2016-02-17" version="1">MGSGSATGSIAAGKRRRAAPDRRAETIGDPAAPPRASHRVRRLRRWHLRNRCALSEDVAFANEGAPPTMTLPPGTVLRPILPRDDAALAAIARQVLAEFGSGLASDPEVDAMQRAYSRPRSAYFVVERDGRLGGGVGIAPLLGGEEGVCELRKFYLLPNVRGIGLGQALLDQCLLSARGFGFGQCYVEVLDRMSEAQRLLERNGFQLLQARMGYGELRGSNTWYLRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFV0</accession>
    <name>A0A0S2DFV0_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2127</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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        <property type="gene ID" value="GLE_2127"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594769" evidence="2">
        <location>
            <begin position="21"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="164" mass="17073" checksum="3DE58DE8A8407A5F" modified="2016-02-17" version="1">MNRKLLALACLAALALSACNKPGETPAAAPAETPKAAEPAAPTEPAPAPAADAAPAAFDAAAFAGTFSGTLPCADCSGIDTKLELKADGSYALSESYQGKKDGNFKGDGTWTAEENGKRVRLDPNSKSDDDRLFEIASKDEIRMLDTEGKPIESQLNYSLKRAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFW2</accession>
    <name>A0A0S2DFW2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type IV fimbrial biogenesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">fimV</name>
        <name evidence="4" type="ORF">GLE_2144</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2144"/>
    <dbReference type="EnsemblBacteria" id="ALN57494">
        <property type="protein sequence ID" value="ALN57494"/>
        <property type="gene ID" value="GLE_2144"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2144"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2108"/>
    <dbReference type="OMA" id="LIEVEWG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038440">
        <property type="entry name" value="FimV_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020011">
        <property type="entry name" value="Motility_prot_FimV_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020012">
        <property type="entry name" value="Motility_prot_FimV_N"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03505">
        <property type="entry name" value="FimV_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03504">
        <property type="entry name" value="FimV_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594969" evidence="3">
        <location>
            <begin position="24"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="136"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="487"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="396"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="206"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="492"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="532"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="584"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="605"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="749" mass="77681" checksum="735F5904C94280CA" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG10</accession>
    <name>A0A0S2DG10_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dyp-type peroxidase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Dyp-type peroxidase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_09625</name>
        <name evidence="3" type="ORF">GLE_1879</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1879"/>
    <dbReference type="EnsemblBacteria" id="ALN57231">
        <property type="protein sequence ID" value="ALN57231"/>
        <property type="gene ID" value="GLE_1879"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1879"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1850"/>
    <dbReference type="OMA" id="KPAWAHN"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006314">
        <property type="entry name" value="Dyp_peroxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04261">
        <property type="entry name" value="Dyp_perox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01413">
        <property type="entry name" value="Dyp_perox_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51404">
        <property type="entry name" value="DYP_PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 3" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="327" mass="35691" checksum="1AAFA0401516D693" modified="2016-02-17" version="1">MAAIVSQPIVAGLTRSAVFLVVTLRPEAQHRQTVRALCADLAGLLRSVGFRDLDGRLSCILAFGDAAWERLFGAPKPADLHPFRAIEGKHRAVSTPGDLLFHIRAERMDLCFELTAQILARLGEAVASAEEVHGFRYFDQRDLLGFVDGTENPVDQEALDSAIVGAEDADFAGGSYVIVQKYLHDLKGWESLPVEQQERIVGRHKLSNVELDDAAKPSYAHNVLTVIEENGEELSIVRDNMPFGDASKSEFGTYFIGYARQPRRIERMLENMFVGNPPGNYDRLLDFSRAVTGTLFFAPSATFLAALPDEDGDAQGAAAGPVATTVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG27</accession>
    <name>A0A0S2DG27_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0125 protein FE772_11220</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_11220</name>
        <name evidence="3" type="ORF">GLE_2226</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0125 (RnfH) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947378.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2226"/>
    <dbReference type="EnsemblBacteria" id="ALN57575">
        <property type="protein sequence ID" value="ALN57575"/>
        <property type="gene ID" value="GLE_2226"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2226"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2191"/>
    <dbReference type="OMA" id="WPDRYSS"/>
    <dbReference type="OrthoDB" id="1921802at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00460">
        <property type="entry name" value="UPF0125_RnfH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005346">
        <property type="entry name" value="RnfH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037021">
        <property type="entry name" value="RnfH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37483">
        <property type="entry name" value="PTHR37483"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03658">
        <property type="entry name" value="Ub-RnfH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="89" mass="9819" checksum="02E8D4548B27D05F" modified="2016-02-17" version="1">MKVEVVRAWPRRFQVMSLELAEGATLGQAVAAAGFDGDAEAVGYAVFGVRAGADTVLREGDRVELLRPLQVDPKDARRRRAEERPLKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG71</accession>
    <name>A0A0S2DG71_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_19445</name>
        <name evidence="5" type="ORF">D9T17_12650</name>
        <name evidence="4" type="ORF">FE772_10270</name>
        <name evidence="2" type="ORF">GLE_2024</name>
    </gene>
    <organism evidence="2 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">C3</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 9" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000056">
        <property type="protein sequence ID" value="OPD62235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000031">
        <property type="protein sequence ID" value="ROU06694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947221.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000031.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57374">
        <property type="protein sequence ID" value="ALN57374"/>
        <property type="gene ID" value="GLE_2024"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62235">
        <property type="protein sequence ID" value="OPD62235"/>
        <property type="gene ID" value="BV903_19445"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2024"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1989"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595119" evidence="1">
        <location>
            <begin position="29"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU06694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="113" mass="12324" checksum="DA9C0455C3D5B3DE" modified="2016-02-17" version="1">MNRRTLRTAPIRYAFAAVLAAAMPAALAAPLDCANYTSAVTPAPYNTWTAVDAYCPSDRSATGGGYFFHEGSLGVPNIWVMHIPLSNGWRTWVDNQNAGPRNVQTYVRCCKTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGC5</accession>
    <name>A0A0S2DGC5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hsp90xo protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_2262</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2262"/>
    <dbReference type="EnsemblBacteria" id="ALN57611">
        <property type="protein sequence ID" value="ALN57611"/>
        <property type="gene ID" value="GLE_2262"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2262"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2227"/>
    <dbReference type="OMA" id="GFEEMLF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="PTHR11528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="623" mass="67595" checksum="EB96349EBD497566" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGF6</accession>
    <name>A0A0S2DGF6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_10535</name>
        <name evidence="2" type="ORF">GLE_2082</name>
    </gene>
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        </lineage>
    </organism>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW28706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2082"/>
    <dbReference type="EnsemblBacteria" id="ALN57432">
        <property type="protein sequence ID" value="ALN57432"/>
        <property type="gene ID" value="GLE_2082"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2082"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2047"/>
    <dbReference type="OMA" id="LYIERWP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
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        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
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        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <begin position="41"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="196" mass="21896" checksum="87F6D72E80607A36" modified="2016-02-17" version="1">MASAAPALAFPPRAERTDLPAPPEGRGDGFDLPASLSERGIGLRPARADDIGWLRALYRQLRAGEFAPMGWPPQALAAFLDQQFAMQHLHYVRYYERADFLVVEREGAPIGRIYLQRAAPEHLLVDISLDARTHGSGIGGGLVRWAQHEAHARGRGMRLHVEHGNHGARRLYERLGFVLTENLPTHAAMRWESDLR</sequence>
</entry>
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    <accession>A0A0S2DGJ2</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
    <gene>
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    <organism evidence="2 3">
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        <lineage>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57685">
        <property type="protein sequence ID" value="ALN57685"/>
        <property type="gene ID" value="GLE_2336"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2336"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="37" mass="3934" checksum="27AEA2C2C8DCD53A" modified="2016-02-17" version="1">MRGQQPALRELAVTPPAEASARRAGERNGAAGRPPFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGN1</accession>
    <name>A0A0S2DGN1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_11345</name>
        <name evidence="4" type="ORF">GLE_2251</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW26178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947401.1">
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    </dbReference>
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        <property type="gene ID" value="GLE_2251"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2251"/>
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    <dbReference type="OrthoDB" id="2108336at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
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        <property type="entry name" value="Wzy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
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        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
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        <location>
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            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
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            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="176"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
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            <end position="216"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
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            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
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    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
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    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="397" mass="42598" checksum="29B8CDE6FEE70442" modified="2016-02-17" version="1">MRIPAPKLLLAPACLGLFLLSGWASVFFAVDTDLIQYAAIAATIALGGLSLSYSGLNRFACLLPVIACLIAFAQIAYLDTHIGHRPKELKFYLILVFCAYCACFVLRGAAAEQFVKIYVALCFMLSVAALAMNKGADTGAQRLMQGDGNPIWIARAAGTAIMFLAYRLLTETRLRGLRIALILPCVAALVLAGSRGPILSLLLGLGVLLVLTNRGALLLSRKVWAAGLAVLLLGVAAAALAPDGIKERLASLVVSNYSGSDVLRMNLYDVSFAMLRDTLFGKGFGAFEASGALQPYPHNLLIEALIEPGLVFAAFFFALIVYAIVRLYRSAKRSQGRDLVATFLCALSVYSLANAMFSGDITSPKELYLCVFYALSTALVLRGSIVQRPPRFQPAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGS8</accession>
    <name>A0A0S2DGS8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase</fullName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_11410</name>
        <name evidence="4" type="ORF">GLE_2264</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.26" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947409.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2264"/>
    <dbReference type="EnsemblBacteria" id="ALN57613">
        <property type="protein sequence ID" value="ALN57613"/>
        <property type="gene ID" value="GLE_2264"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2264"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2229"/>
    <dbReference type="OMA" id="PDENCET"/>
    <dbReference type="OrthoDB" id="890789at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003948">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
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        <property type="entry name" value="Peptidase_T2"/>
    </dbReference>
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        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188">
        <property type="entry name" value="PTHR10188"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01112">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242310" evidence="3">
        <location>
            <begin position="25"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="195"/>
        </location>
    </feature>
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        <location>
            <begin position="194"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57613.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW26189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="340" mass="35826" checksum="A87DD27262F6C476" modified="2016-02-17" version="1">MTTRRSFLHSSLLAAGAAALPAFAADKPPAPKAIDGARVVSTWDFGVGANQAAWKVLGEGGAALDAVEAGARWAEADLCNSTVGRCGNPDRDGVLTLDASIMDGDGRCGAVAALEDIAHPVSVARRVMERTPHVLLAGAGAQQFAIEQGFPKQALLTDKARAAWNEWRKTAKYQPAINAERLDNAKPGDKHNHDTLGILAIDRSGKLAGACTTSGMAWKLHGRVGDSPIVGAGLYVDNDVGAATASGVGEEMLRNAASFLVVELMRQGRSPDDACREAIERVVRKRPQASKTLQVCFLAIDKHGEVGAHALHRGFVYAVCDAGKRDALLDARSVYATEQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGT2</accession>
    <name>A0A0S2DGT2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="gene ID" value="GLE_2460"/>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN57809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="432" mass="46286" checksum="8ED68604D6B20E67" modified="2016-02-17" version="1">MQRAAAALAALALIAYLALSPALLTVLGIPYDAPYGPFWFKLHPGDYPLLLALACSLAARGNPLLEALRRLRAHPLLAAYLTAMASIFAYSLLRHGPSGSAFFIDTLMMPAAMALVLVAMDEAELRRLWRLLLAAVLVNAAIGLAEAASQRHLVPYTVAGGVAVIEDKFRATALHGHPLENAMLTGIALLAALDLPMPPRRRWALCALLVLALLAFGGRASFLLSVAALAAWAALRAREGLRAGRYGYLHIVGASLAGLVAAPMAAAAVWKSGLGARIFQGLYLDDSAAVRLRIFDVFDHLDGFDLLFGIAPQQIQELSLRIGLSQNLEAIENFWLFMLLQLGAFGFLAFAAGLGCGLYWLWRRADGGARWALLVFLATASTTNSLASKTSALTLLFALLCCVRGYRGRRLAQPQPRPAPPRRIAMRTGATA</sequence>
</entry>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
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        <subcellularLocation>
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        </subcellularLocation>
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        <text evidence="6">Belongs to the TonB-dependent receptor family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <source>
            <dbReference type="RuleBase" id="RU003357"/>
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        <source>
            <dbReference type="EMBL" id="ALN57894.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW26408.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="974" mass="106698" checksum="94A8EEC6ED36B37F" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH63</accession>
    <name>A0A0S2DH63_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">TonB dependent receptor</fullName>
        </submittedName>
    </protein>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <location>
            <begin position="86"/>
            <end position="486"/>
        </location>
    </feature>
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        <location>
            <begin position="287"/>
            <end position="313"/>
        </location>
    </feature>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN57731.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="523" mass="59650" checksum="CC25BA01416CE17E" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH75</accession>
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            <fullName evidence="2">Histidine kinase</fullName>
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    </protein>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
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        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
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        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="310"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="649"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="79"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN57980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="876" mass="94237" checksum="0E88E7E746F26EA8" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH98</accession>
    <name>A0A0S2DH98_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA-binding response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Response regulator transcription factor</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Transcriptional regulatory protein, C terminal-DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BV903_00020</name>
        <name evidence="8" type="ORF">FE772_12870</name>
        <name evidence="6" type="ORF">GLE_2564</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">C3</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000001">
        <property type="protein sequence ID" value="OPD65938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947640.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2564"/>
    <dbReference type="EnsemblBacteria" id="ALN57913">
        <property type="protein sequence ID" value="ALN57913"/>
        <property type="gene ID" value="GLE_2564"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65938">
        <property type="protein sequence ID" value="OPD65938"/>
        <property type="gene ID" value="BV903_00020"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2564"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2523"/>
    <dbReference type="OMA" id="RHVWQYE"/>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="124"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="124"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD65938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW26425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="227" mass="24860" checksum="EF967D78C7AAC351" modified="2016-02-17" version="1">MRILLVEDDQGLSQALKSALAAHSIVLDVAADLGAARRALSDADYRVLILDWQLPDGEGISLIPLARRAQPGLPVLILTARHQVEDRIQGLDAGADDYITKPFDVNELLARIRAVCRRPTQQQIPSMTLGALQFDFGDRCASLHGVRLNLPRRQLLVLEALCLRAGRTVSRAKLQEAVYGFDDNIESNTLESHISRLRRTLAPAGIEIHAMRGLGYLLQAADGADES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHC4</accession>
    <name>A0A0S2DHC4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase C69</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">TldD/PmbA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BV903_18765</name>
        <name evidence="7" type="ORF">FE772_13375</name>
        <name evidence="5" type="ORF">GLE_2669</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase U62 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000052">
        <property type="protein sequence ID" value="OPD62397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947720.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000052.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2669"/>
    <dbReference type="EnsemblBacteria" id="ALN58017">
        <property type="protein sequence ID" value="ALN58017"/>
        <property type="gene ID" value="GLE_2669"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62397">
        <property type="protein sequence ID" value="OPD62397"/>
        <property type="gene ID" value="BV903_18765"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2669"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2628"/>
    <dbReference type="OMA" id="TCLWYIR"/>
    <dbReference type="OrthoDB" id="958356at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045569">
        <property type="entry name" value="Metalloprtase-TldD/E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045570">
        <property type="entry name" value="Metalloprtase-TldD/E_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002510">
        <property type="entry name" value="Metalloprtase-TldD/E_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035068">
        <property type="entry name" value="TldD/PmbA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036059">
        <property type="entry name" value="TldD/PmbA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01523">
        <property type="entry name" value="PmbA_TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19289">
        <property type="entry name" value="PmbA_TldD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19290">
        <property type="entry name" value="PmbA_TldD_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111283">
        <property type="entry name" value="SSF111283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PmbA_TldD" evidence="2">
        <location>
            <begin position="28"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_M" evidence="4">
        <location>
            <begin position="137"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_C" evidence="3">
        <location>
            <begin position="222"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD62397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW26505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
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        </source>
    </evidence>
    <sequence length="444" mass="48448" checksum="C0EC05F4485E9F43" modified="2016-02-17" version="1">MSIFTEAQSKAILDKVIALSKADETSARLTGSIDGNIRFALNNISTSGVVSDVDLAVQVSFGKRVGVATINEFDDAALERVVRRAEDLAKLAPENPEFMPIIDKQTYKPSPTFSASTAAIDPAFRAKVAADSIAPCREAKLTAAGFLEDGQSFVAFANSKGNFGYQTATNFNYTCTVRTDDGRGSGWVGRDLTDADAFKADADIRIAMRKATESAEAKALEPGKYTVILEPHAAAGLISFMMNFFDARQADEGRSFLSKKGGGNKLGEQVYDPRVNFLADPWDPRAPVMPWDGEGLPREKMPIVENGKVVALNYSRYWAQKQGKRAVGTPGNLLMSGGDKTTAELVKGTQKGILVTRTWYIRMVDPQTVLLTGLTRDGTFYIENGQIKHPIKNFRFNESPVIMLNNIEELGRPVRVAGDESDSVMMIPPMKLRDFTFTSLSDAV</sequence>
</entry>
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    </evidence>
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</entry>
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</entry>
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</entry>
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    <accession>A0A0S2DIU8</accession>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <source>
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        <source>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
    <sequence length="1026" mass="109946" checksum="4CD43015B6C03797" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIY5</accession>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="RefSeq" id="WP_057948023.1">
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    </dbReference>
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        <property type="protein sequence ID" value="ALN58418"/>
        <property type="gene ID" value="GLE_3071"/>
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    <dbReference type="OrthoDB" id="2093207at2"/>
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    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726668" evidence="1">
        <location>
            <begin position="33"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="78" mass="8300" checksum="97B9DC2DB05B6C1F" modified="2016-02-17" version="1">MTTKQLPGPLRRWRATAALAAFAFAFAFGATAASRDIIVCGGGVYCDAEVRQPCLDSGKSAAFCDRLWRGCVLDACPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ23</accession>
    <name>A0A0S2DJ23_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ferredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BV903_09375</name>
        <name evidence="12" type="ORF">D9T17_12220</name>
        <name evidence="11" type="ORF">FE772_15800</name>
        <name evidence="9" type="ORF">GLE_3180</name>
    </gene>
    <organism evidence="9 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 13">C3</strain>
        </source>
    </reference>
    <reference evidence="10 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">OH11</strain>
        </source>
    </reference>
    <reference evidence="11 16" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 16">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 7">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="OPD64244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW26886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000030">
        <property type="protein sequence ID" value="ROU06761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948102.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000030.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3180"/>
    <dbReference type="EnsemblBacteria" id="ALN58526">
        <property type="protein sequence ID" value="ALN58526"/>
        <property type="gene ID" value="GLE_3180"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64244">
        <property type="protein sequence ID" value="OPD64244"/>
        <property type="gene ID" value="BV903_09375"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3180"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3135"/>
    <dbReference type="OMA" id="DRMLYIH"/>
    <dbReference type="OrthoDB" id="1873445at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000813">
        <property type="entry name" value="7Fe_ferredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022569">
        <property type="entry name" value="Fd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11953">
        <property type="entry name" value="DUF3470"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00354">
        <property type="entry name" value="7FE8SFRDOXIN"/>
    </dbReference>
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        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4 7" id="KW-0408">Iron</keyword>
    <keyword evidence="5 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="31"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN58526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD64244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW26886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROU06761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="107" mass="11935" checksum="AE7D1504B8C12A67" modified="2016-02-17" version="1">MPFVVTENCIKCKYTDCVEVCPVDCFHEGPNFLVIDPDECIDCTLCEPECPINAIYPEDDVPAGQEAFVALNAELAQAWPVITTRKDSLPDAKEWEGKTGKIDLLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ48</accession>
    <name>A0A0S2DJ48_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">YaeQ family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_24170</name>
        <name evidence="3" type="ORF">FE772_15595</name>
        <name evidence="1" type="ORF">GLE_3135</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD61341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_MTAY01000091.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3135"/>
    <dbReference type="EnsemblBacteria" id="ALN58482">
        <property type="protein sequence ID" value="ALN58482"/>
        <property type="gene ID" value="GLE_3135"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD61341"/>
        <property type="gene ID" value="BV903_24170"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3135"/>
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD61341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="186" mass="20720" checksum="19F996BA4D966D12" modified="2016-02-17" version="1">MALNATIVKIELQISDMDRHYYAAHALTLAQHPSETQQRLMVRTLAFALNAHERLEFGPGLSAEGEEPEIALRDYTGDIELWIDVGQPDESRIRKACGRSRQVVVVNYGGNAADIWWDKNANALQRLKNLSVIDIDSACVEAMAAMVERSFRLDCQIQDGEVTLTTDKASLSLVPRRRLDAGVRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJI4</accession>
    <name>A0A0S2DJI4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">OmpA/MotB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_16310</name>
        <name evidence="3" type="ORF">GLE_3296</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948187.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58642">
        <property type="protein sequence ID" value="ALN58642"/>
        <property type="gene ID" value="GLE_3296"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3296"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3246"/>
    <dbReference type="OrthoDB" id="1261578at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpA-like" evidence="2">
        <location>
            <begin position="211"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="314" mass="31369" checksum="E6380E2CFA5CF650" modified="2016-02-17" version="1">MRTARSNHRPDSRAGRADIVAGGASRSGALAAAALLAALAGLSACNRNAPATDAAPVAEAAAPAAAAPVAPVEAKLGLANNNGAIRYDGRVDSEATRKALAIALAQAYSGQIAGDLEVGKAVKPAPWQDKLPQFVAALTMSGVAVTFEGDSIELSGQASDADRALLLEKAKTLFPGFRYGGLFEGVGGEAASSDAAAQALAALVPGKSGAGEIAQALNKIEVRFEEGGARIAPASLDILSRAAKALAAGPKDARYEIVGPGGGAGQPADNEILSRQRAEAVKVQLIVAGANPGALDTRGEPGTAATPLKFNPVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJX1</accession>
    <name>A0A0S2DJX1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58786">
        <property type="protein sequence ID" value="ALN58786"/>
        <property type="gene ID" value="GLE_3441"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3441"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="62" mass="6724" checksum="17BE5D15022AD45C" modified="2016-02-17" version="1">MVVSRIVVRSFDRRASRGAASSLRVRRDRGKCARGLAARAVASPDRRRINAAASDGLARSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK02</accession>
    <name>A0A0S2DK02_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_08780</name>
        <name evidence="5" type="ORF">D9T17_10560</name>
        <name evidence="3" type="ORF">GLE_3518</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000019">
        <property type="protein sequence ID" value="OPD64271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000024">
        <property type="protein sequence ID" value="ROU06957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948351.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3518"/>
    <dbReference type="EnsemblBacteria" id="ALN58862">
        <property type="protein sequence ID" value="ALN58862"/>
        <property type="gene ID" value="GLE_3518"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64271">
        <property type="protein sequence ID" value="OPD64271"/>
        <property type="gene ID" value="BV903_08780"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3518"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3462"/>
    <dbReference type="OMA" id="LWFYTLA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="276"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD64271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU06957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <sequence length="394" mass="42157" checksum="612ADDD13973E280" modified="2016-02-17" version="1">MRTPGPPLDAHDNLLGWHLASLLYLSFVFIPVFNFPAPWWILALAIGSVLVFLPLYWAFYRGGATLRLWLVLAVAALGFATVPFGIGGGTYLIFAAGMIASFLPLWRGLALTAALFALFAAESIATLPAQGAPVFSVLIQALVGAIVFTGVLAARSRERRNAELRLTQEEVRRLASLAERERIGRDLHDLLGHTLSVVVLKSQLAARLIEHDKCAAQDQISEVERVAREALTQVREAVAGIRANGLQAELAAARLALLGGEISLDQRLDPIDLPVAVETALALALRESVTNVLRHARARRVEVELTEDPRGGIVLRVVDDGRGGVSAEGHGLTGMRERLRSVGGVLEIESPPGAGTRLSLLVSREALNAARRLPAAVAPAGSVRQPALLERGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK27</accession>
    <name>A0A0S2DK27_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BlaI/MecI/CopY family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Penicillinase repressor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_16640</name>
        <name evidence="2" type="ORF">GLE_3371</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BlaI transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948247.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3371"/>
    <dbReference type="EnsemblBacteria" id="ALN58717">
        <property type="protein sequence ID" value="ALN58717"/>
        <property type="gene ID" value="GLE_3371"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3371"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3321"/>
    <dbReference type="OMA" id="RYATQTP"/>
    <dbReference type="OrthoDB" id="2027769at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005650">
        <property type="entry name" value="BlaI_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34134">
        <property type="entry name" value="PTHR34134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03965">
        <property type="entry name" value="Penicillinase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019455">
        <property type="entry name" value="CopR_AtkY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="128" mass="14073" checksum="B5AFF29E1448A32D" modified="2016-02-17" version="1">MARKSIGDQELALLNYLSERGDTSVGEVAADFGEARGLARSTVLTMMERLRAKAYLRRRKVGGVYRYATQTPADDVMRSAVGSFVANTLQGSLSPFVAWMSQRAQVSDAELAELESLVADLQARRKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKD9</accession>
    <name>A0A0S2DKD9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">TldD/PmbA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_3405</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase U62 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948271.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3405"/>
    <dbReference type="EnsemblBacteria" id="ALN58751">
        <property type="protein sequence ID" value="ALN58751"/>
        <property type="gene ID" value="GLE_3405"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3405"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3354"/>
    <dbReference type="OMA" id="TDFWGSM"/>
    <dbReference type="OrthoDB" id="806701at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045569">
        <property type="entry name" value="Metalloprtase-TldD/E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045570">
        <property type="entry name" value="Metalloprtase-TldD/E_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002510">
        <property type="entry name" value="Metalloprtase-TldD/E_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025502">
        <property type="entry name" value="TldD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035068">
        <property type="entry name" value="TldD/PmbA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036059">
        <property type="entry name" value="TldD/PmbA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01523">
        <property type="entry name" value="PmbA_TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19289">
        <property type="entry name" value="PmbA_TldD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19290">
        <property type="entry name" value="PmbA_TldD_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004919">
        <property type="entry name" value="TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111283">
        <property type="entry name" value="SSF111283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PmbA_TldD" evidence="3">
        <location>
            <begin position="39"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_M" evidence="5">
        <location>
            <begin position="127"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_C" evidence="4">
        <location>
            <begin position="244"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF19290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="480" mass="50575" checksum="3AD065FAFDCE4A8A" modified="2016-02-17" version="1">MTLPIQLAESRLLLPAGLDASGLERSFGTLLGPGIDFGDLYFQHSRRESWTVEDGIVKDGAHSIEQGVGVRAISGEKTGFAYSDEINGEALLGAAKSARAIARDGGAQAPRALVRGGGRSLYRSEDPIDSVSNEAKVEALRQLDQLLRAADPRVRQVVVSLNGVLDTVLVARSDGVLAADVRPLVRLNVQVLVEQNGRRESGYAGGGGRYSYAELLASDRPQRWAREALRQALVNLDAVDAPAGVMPVVLGSGWPGVLLHEAVGHGLEGDFNRKGTSTYAGRMGQRVAAKGVTIVDDGTLEGRRGSLNVDDEGTPTNCTTLIEDGVLVGYMQDTLNARLMGMEPTGNGRRESFAHLPMPRMTNTYMLAGAHDPEEMIRSVKKGLYAVNFGGGQVDITSGKYVFSATEAYLIEDGRITAPVKGATLIGNGPETMQKVSMIGHDLALDEGVGVCGKDGQSVAVGVGQPSLLIDGLTVGGTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKE6</accession>
    <name>A0A0S2DKE6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3635</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58979">
        <property type="protein sequence ID" value="ALN58979"/>
        <property type="gene ID" value="GLE_3635"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3635"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3579"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="79" mass="8393" checksum="758CAE047487E5C9" modified="2016-02-17" version="1">MREGRLRAAFLFLFVSDRRVGSSPIVGAARAATAIPRLRRICGFAVAACAAPTGASAVSRLPELASRHHRALPVRADPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKH5</accession>
    <name>A0A0S2DKH5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLE_3703</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948486.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3703"/>
    <dbReference type="EnsemblBacteria" id="ALN59047">
        <property type="protein sequence ID" value="ALN59047"/>
        <property type="gene ID" value="GLE_3703"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3703"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3647"/>
    <dbReference type="OMA" id="MRFANER"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13188">
        <property type="entry name" value="PAS_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="45"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="8">
        <location>
            <begin position="534"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="8">
        <location>
            <begin position="656"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="720"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="968"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="1017"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN59047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1090" mass="119182" checksum="1DCB94244ABA9AE3" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKH6</accession>
    <name>A0A0S2DKH6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">General stress protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_07535</name>
        <name evidence="4" type="ORF">FE772_18210</name>
        <name evidence="2" type="ORF">GLE_3696</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000014">
        <property type="protein sequence ID" value="OPD64607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948479.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000014.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3696"/>
    <dbReference type="EnsemblBacteria" id="ALN59040">
        <property type="protein sequence ID" value="ALN59040"/>
        <property type="gene ID" value="GLE_3696"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64607">
        <property type="protein sequence ID" value="OPD64607"/>
        <property type="gene ID" value="BV903_07535"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3696"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3640"/>
    <dbReference type="OMA" id="KFGWEIA"/>
    <dbReference type="OrthoDB" id="1804797at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038725">
        <property type="entry name" value="YdaG_split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16242">
        <property type="entry name" value="Pyrid_ox_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyrid_ox_like" evidence="1">
        <location>
            <begin position="9"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="161" mass="18264" checksum="65001D40E892441B" modified="2016-02-17" version="1">MTDSQALERKLWKHLHDDRTIMLGVEGENGHSRPMTALAEGDRSPLWIFTARDNELVRRLERPARAVAAFVAKDHSVFASIEGELHLDIDRAVIDRLWNPFIAAWYEGGKDDPNLALLRFDASSAEVWLNENSLLAGMKLLLGMDPKREYADKVGEVDLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKX8</accession>
    <name>A0A0S2DKX8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">30S ribosomal protein S13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">rpsM</name>
        <name evidence="9" type="ORF">BV903_22930</name>
        <name evidence="11" type="ORF">D9T17_09535</name>
        <name evidence="10" type="ORF">FE772_18545</name>
        <name evidence="8" type="ORF">GLE_3769</name>
    </gene>
    <organism evidence="8 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 12">C3</strain>
        </source>
    </reference>
    <reference evidence="9 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">OH11</strain>
        </source>
    </reference>
    <reference evidence="10 15" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000077">
        <property type="protein sequence ID" value="OPD61596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000023">
        <property type="protein sequence ID" value="ROU07202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948536.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3769"/>
    <dbReference type="EnsemblBacteria" id="ALN59113">
        <property type="protein sequence ID" value="ALN59113"/>
        <property type="gene ID" value="GLE_3769"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61596">
        <property type="protein sequence ID" value="OPD61596"/>
        <property type="gene ID" value="BV903_22930"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3769"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3713"/>
    <dbReference type="OMA" id="YRGLRHK"/>
    <dbReference type="OrthoDB" id="1772647at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01315">
        <property type="entry name" value="Ribosomal_S13_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="30s_Rbsml_prot_S13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_S13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019980">
        <property type="entry name" value="Ribosomal_S13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018269">
        <property type="entry name" value="Ribosomal_S13_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF1">
        <property type="entry name" value="PTHR10871:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002134">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03631">
        <property type="entry name" value="uS13_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00646">
        <property type="entry name" value="RIBOSOMAL_S13_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD61596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROU07202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="118" mass="13317" checksum="85D3329BF50F9270" modified="2016-02-17" version="1">MARIAGVNLPAQKHVWVGLQSIYGIGRTRSKQICETAGVTSSTKIRDLSEPEVERLRAEVGKFVVEGDLRREIGIAIKRLMDLGCYRGLRHRRGLPLRGQRTRTNARTRKGPRKAIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLQ0</accession>
    <name>A0A0S2DLQ0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_4205</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4205"/>
    <dbReference type="EnsemblBacteria" id="ALN59546">
        <property type="protein sequence ID" value="ALN59546"/>
        <property type="gene ID" value="GLE_4205"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4205"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4147"/>
    <dbReference type="OMA" id="MLSCGTG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010619">
        <property type="entry name" value="ThrE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024528">
        <property type="entry name" value="ThrE_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06738">
        <property type="entry name" value="ThrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12821">
        <property type="entry name" value="ThrE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="190"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="274"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="316"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="356"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="390"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="426"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="ThrE" evidence="6">
        <location>
            <begin position="55"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="ThrE_2" evidence="7">
        <location>
            <begin position="323"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="453" mass="48326" checksum="ABEED95239BE8DFA" modified="2016-02-17" version="1">MRRAAMRERRPSMPCRCADGERAAAAQARARVPCFADMSVPHPLSATSYAARIAFVVELAERLHSYGTTAQRLEGAVTSVAQKLRLECEPWSNPTGLILTFSDPQRPMGDSDTTRVIRLPPGENDLYRLSETDRIAEDVMAGRLDLAAGHAALEALDRPRTRRWRAMQVFGYGLAAGAVAALLRLPWLDIGVAAVNGLMIGLLVDVSGQRPRLREALEAIAGMFAAAAVVLVANFVAPLNQNTVIIASLIVLLPGMALTNAVNELTSQHLVSGTARFAGAVTTVVKLAVGTVIGLYLADLVGLEPVVRAWRPQDGWVEWAGLAVASYAFAVLFRAHRADYPKVMAAAAGGYLISRFVGLAWGSPAGIFLAALVMTALGNAYARWGNRPGAILRVPGIILLVPGSVSLRGLLNMLQQQDVQVGQDAVLAVVNILLALIAGLIFGNLLLPSRRNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLQ7</accession>
    <name>A0A0S2DLQ7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Translation initiation factor IF-2-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59247">
        <property type="protein sequence ID" value="ALN59247"/>
        <property type="gene ID" value="GLE_3905"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3905"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3842"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="107" mass="10784" checksum="A0FA3FA524B69EFE" modified="2016-02-17" version="1">MRRGVGSHGVHDTGAVAKRVFADVAAPRSGTKASGLKALPPQPGLRATARCPAPACKALVGGPSGPTLSDQPTGINHLAPSPDPVGTFAPSFFRMAASTPPRPEPDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM58</accession>
    <name>A0A0S2DM58_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59556">
        <property type="protein sequence ID" value="ALN59556"/>
        <property type="gene ID" value="GLE_4215"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4215"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4157"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="50" mass="5223" checksum="EF0422DB584AFA91" modified="2016-02-17" version="1">MRPLRGRAGAPAVAPRSSGSWKRCKKSSACWAGTVSSRRGSCAARTVLCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMC8</accession>
    <name>A0A0S2DMC8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3-oxoacid CoA-transferase, A subunit family</fullName>
            <ecNumber evidence="3">2.8.3.-</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="5">CoA transferase subunit A</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Succinyl-CoA--3-ketoacid-CoA transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_04355</name>
        <name evidence="5" type="ORF">FE772_20705</name>
        <name evidence="3" type="ORF">GLE_4228</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 3-oxoacid CoA-transferase subunit A family.</text>
    </comment>
    <dbReference type="EC" id="2.8.3.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000008">
        <property type="protein sequence ID" value="OPD65157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948884.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000008.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4228"/>
    <dbReference type="EnsemblBacteria" id="ALN59569">
        <property type="protein sequence ID" value="ALN59569"/>
        <property type="gene ID" value="GLE_4228"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65157">
        <property type="protein sequence ID" value="OPD65157"/>
        <property type="gene ID" value="BV903_04355"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4228"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4169"/>
    <dbReference type="OMA" id="QLAPECI"/>
    <dbReference type="OrthoDB" id="1660857at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008410">
        <property type="term" value="F:CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012792">
        <property type="entry name" value="3-oxoacid_CoA-transf_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004165">
        <property type="entry name" value="CoA_trans_fam_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004163">
        <property type="entry name" value="CoA_transf_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13707">
        <property type="entry name" value="PTHR13707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01144">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00882">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02429">
        <property type="entry name" value="pcaI_scoA_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01273">
        <property type="entry name" value="COA_TRANSF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD65157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW27697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="238" mass="25488" checksum="34872A027B4A3D51" modified="2016-02-17" version="1">MADAVAAKSKLYPNAHDALQGVVADGQTLAVGGFGLCGIPEALIGALRDSGAKGLTAISNNAGVDGFGLGLLLETRQIKKMISSYVGENKEFERQFLSGELELEFNPQGTLAERLRAGGAGIPAFFTRTGYGTVVAEGKETREFDGHHYVMETALKADVSLVKAWKADKAGNLVFRKTARNFNPACAMAGKVCIVEVEELVEIGQLDPDQVHLPGIYVDRIVVNATPEKRIEQRTVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DML7</accession>
    <name>A0A0S2DML7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine hydroxymethyltransferase</fullName>
            <shortName evidence="7">SHMT</shortName>
            <shortName evidence="7">Serine methylase</shortName>
            <ecNumber evidence="7">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">glyA</name>
        <name evidence="11" type="ORF">BV903_07740</name>
        <name evidence="12" type="ORF">FE772_20405</name>
        <name evidence="10" type="ORF">GLE_4161</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">C3</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; glycine biosynthesis; glycine from L-serine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the SHMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000015">
        <property type="protein sequence ID" value="OPD64544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948837.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4161"/>
    <dbReference type="EnsemblBacteria" id="ALN59503">
        <property type="protein sequence ID" value="ALN59503"/>
        <property type="gene ID" value="GLE_4161"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64544">
        <property type="protein sequence ID" value="OPD64544"/>
        <property type="gene ID" value="BV903_07740"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4161"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4103"/>
    <dbReference type="OMA" id="SHPAGLI"/>
    <dbReference type="OrthoDB" id="861782at2"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="UniPathway" id="UPA00288">
        <property type="reaction ID" value="UER01023"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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            <begin position="11"/>
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    </evidence>
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        <source>
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    <sequence length="429" mass="46064" checksum="2AB7A21EE662B5DD" modified="2016-02-17" version="1">MFPSTTRIAGFDDELAQAIADEARRQEDHVELIASENYASPRVLEAQGSVLTNKYAEGYPGKRYYGGCEYVDIAEQLAIDRVKQLYGADYANVQPHSGSQANQAVYFALLNPGDTILGMSLAHGGHLTHGAKVNASGKLFNAVQYGVNDQGLIDYDEVERLALEHKPKMIVGGFSAYSQVVDWARFRAIADKVGAFLFVDMAHVAGLIAAGVYPSPVPHAHVVTSTTHKTLRGPRGGIVVAKRWDGAVGDGEGAVGFDDMQKKLQSIVFPGIQGGPLMHVIAAKAVAFKEALEPEFKAYQAQVIKNAQAMAKTIIARGYKIVSGGTENHLMLVDMIGKGITGKDAEAALGRAHITVNKNAVPNDPQKPFVTSGLRIGTPAVTTRGYKEADCVALAEWICDVLDNPKDEKVIAGVRENVTKQCAQFPVYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMM4</accession>
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        <name type="scientific">Lysobacter enzymogenes</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">C3</strain>
        </source>
    </reference>
    <reference evidence="4 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">OH11</strain>
        </source>
    </reference>
    <reference evidence="5 10" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 10">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000019">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_4440"/>
    <dbReference type="EnsemblBacteria" id="ALN59781">
        <property type="protein sequence ID" value="ALN59781"/>
        <property type="gene ID" value="GLE_4440"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD65310"/>
        <property type="gene ID" value="BV903_03165"/>
    </dbReference>
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    <dbReference type="PATRIC" id="fig|69.6.peg.4377"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="84"/>
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    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59781.1"/>
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    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW27871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROU07956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="93" mass="10347" checksum="DAE64271DAB5EE69" modified="2016-02-17" version="1">MDKSRVIDILKQIIAEDLDLNIGYDQVDDAASFLEDGLALDSISMAEFINLLERRFQIRILDEDLESATFQSLDNVAALVQKRLAESACEVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMQ8</accession>
    <name>A0A0S2DMQ8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytoplasmic protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Cytosolic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_21895</name>
        <name evidence="1" type="ORF">GLE_4485</name>
    </gene>
    <organism evidence="1 3">
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        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW28859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949091.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59826">
        <property type="protein sequence ID" value="ALN59826"/>
        <property type="gene ID" value="GLE_4485"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4485"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4422"/>
    <dbReference type="OMA" id="GCFYCLE"/>
    <dbReference type="OrthoDB" id="2006137at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="98" mass="10655" checksum="DBD763089307A85C" modified="2016-02-17" version="1">MSFDLDRAHRHSAGHRAELLASERCGCFYCLAVFLPQAIDEWIDAADDADADSDDNETGTTALCPVCGIDAVIGSAAGFPLQREFLQAMRARWFGGMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMR6</accession>
    <name>A0A0S2DMR6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59661">
        <property type="protein sequence ID" value="ALN59661"/>
        <property type="gene ID" value="GLE_4320"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4320"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4259"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="50" mass="5248" checksum="07F91D54252565C4" modified="2016-02-17" version="1">MGGPSGPMLSAPTPRKSAPGRIRWRRSRTRASTALNPRIDTTAATANEAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMT8</accession>
    <name>A0A0S2DMT8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">TonB-dependent siderophore receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLE_4586</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949165.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4586"/>
    <dbReference type="EnsemblBacteria" id="ALN59927">
        <property type="protein sequence ID" value="ALN59927"/>
        <property type="gene ID" value="GLE_4586"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4586"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4522"/>
    <dbReference type="OMA" id="RNTFYHY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015344">
        <property type="term" value="F:siderophore uptake transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010105">
        <property type="entry name" value="TonB_sidphr_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01783">
        <property type="entry name" value="TonB-siderophor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 11" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594999" evidence="8">
        <location>
            <begin position="32"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="10">
        <location>
            <begin position="85"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="9">
        <location>
            <begin position="307"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN59927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="748" mass="82168" checksum="6EB07C289C6CFF1E" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMU6</accession>
    <name>A0A0S2DMU6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_21995</name>
        <name evidence="1" type="ORF">GLE_4503</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949104.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59844">
        <property type="protein sequence ID" value="ALN59844"/>
        <property type="gene ID" value="GLE_4503"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4503"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4439"/>
    <dbReference type="OrthoDB" id="2168761at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="171" mass="19174" checksum="8D1AE756D71A2187" modified="2016-02-17" version="1">MTASPGIAETTQRIACRAEDAWNAVCFYEHIQRKPSLFLRSVLPVPMRTTGCAGKVGDTSRCMYSDGGYLAKRITELVPGERVEFEVIEHSIRYCRSIALKGGSISVVADGDGACSVHMLTRYELQSRRLRPLRPFIEFTISAMHRIVMRDMQERLEARAANWLYTSGPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMV5</accession>
    <name>A0A0S2DMV5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aminopeptidase N</fullName>
            <ecNumber evidence="3">3.4.11.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">lta4h</name>
        <name evidence="15" type="ORF">FE772_22070</name>
        <name evidence="14" type="ORF">GLE_4519</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">C3</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.</text>
            <dbReference type="EC" id="3.4.11.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M1 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.2" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949117.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4519"/>
    <dbReference type="EnsemblBacteria" id="ALN59860">
        <property type="protein sequence ID" value="ALN59860"/>
        <property type="gene ID" value="GLE_4519"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4519"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4455"/>
    <dbReference type="OMA" id="YHPICRQ"/>
    <dbReference type="OrthoDB" id="771837at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09599">
        <property type="entry name" value="M1_LTA4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038502">
        <property type="entry name" value="M1_LTA-4_hydro/amino_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034015">
        <property type="entry name" value="M1_LTA4H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015211">
        <property type="entry name" value="Peptidase_M1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45726">
        <property type="entry name" value="PTHR45726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09127">
        <property type="entry name" value="Leuk-A4-hydro_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01263">
        <property type="entry name" value="Leuk-A4-hydro_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="SSF63737"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Leuk-A4-hydro_C" evidence="13">
        <location>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
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    <sequence length="111" mass="11594" checksum="3D114FFAD5746E21" modified="2016-02-17" version="1">MQIDYLRVALSLALCLGLGVAAIFLLRSRFRGLSVGPARDLALLESLRVDPRTAVHVLAYQDQRLLLTTRDNAVHVTVLPAGTPAPVASAPPHDAGAQPASHDASDGAPAP</sequence>
</entry>
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    <accession>A0A0S2DNE9</accession>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="GLE_4826"/>
    </dbReference>
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    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595511" evidence="1">
        <location>
            <begin position="26"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN60167.1"/>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="71" mass="7744" checksum="7A712006333161CF" modified="2016-02-17" version="1">MARKTQLAALCTFAFGLSFAAAAFAGQDYDLACVSNCQQIEIERCQAAGGGDECRLINIDHCYYQCPLIYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNH7</accession>
    <name>A0A0S2DNH7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SDR family oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Tropinone reductase</fullName>
            <ecNumber evidence="1">1.1.1.236</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_23595</name>
        <name evidence="1" type="ORF">GLE_4858</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.236" evidence="1"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949366.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4858"/>
    <dbReference type="EnsemblBacteria" id="ALN60199">
        <property type="protein sequence ID" value="ALN60199"/>
        <property type="gene ID" value="GLE_4858"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4858"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4788"/>
    <dbReference type="OMA" id="GICEFKE"/>
    <dbReference type="OrthoDB" id="1294334at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050358">
        <property type="term" value="F:tropinone reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045000">
        <property type="entry name" value="TR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42898">
        <property type="entry name" value="PTHR42898"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="258" mass="28143" checksum="EC76A83D7F96DA84" modified="2016-02-17" version="1">MDPKRWRLDGQLALITGGSAGIGRAIARELLGFGADVLLAARDAAALESARAELVEDFPDREVQAFVADVADDEQRRELLDWVEDFGEGLHILVNNAGGNLSKATNDYTEDEWRQVFEINLFSAFELSRYAHALLTRHAASSIVNVGSVSGSTHVRTGSPYGMSKAAMHQMTRNLAVEWAEDGIRVNAVAPWYIRTRRTSDKLADPDYLDEVLLRTPAGRIGEPEEVAAAVAFLCLPAAAYITGECIAVDGGFLRYGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNW1</accession>
    <name>A0A0S2DNW1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AraC family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_23495</name>
        <name evidence="2" type="ORF">GLE_4836</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949349.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4836"/>
    <dbReference type="EnsemblBacteria" id="ALN60177">
        <property type="protein sequence ID" value="ALN60177"/>
        <property type="gene ID" value="GLE_4836"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4836"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4767"/>
    <dbReference type="OMA" id="RGKKVMH"/>
    <dbReference type="OrthoDB" id="1785082at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009594">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06719">
        <property type="entry name" value="AraC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="215"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="320" mass="35658" checksum="7EEAFB4F7C93BFAD" modified="2016-02-17" version="1">MSASTSADTIAQRGHCAQQAELVDRIARLTVAGDGVHGTDVRQLHLIRMDRPTECSPSVYEPRLCVVAQGRKVVTLSDRVYHYDPLNYLVVSVTLPMIGQVVEATPDKPYLCLRIDIDPAEIARLIVDAGQSPPGERSREARDGIGMDLGLYAARVNATLMDAVLRLMRLLDTPQDLPVLAPMALREIFYRVLMGDLGHRLRALALNDSRSHRIAKAVTMLRQRYLLPLCIEDLADELHMSTSSLHHQFKAVTTMSPLQFQKHLRLHEARRLMMIDGMEAVAAAHRVGYESPSQFSREYKRLFGAPPRAEVSLARGLPLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNY7</accession>
    <name>A0A0S2DNY7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4927</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60268">
        <property type="protein sequence ID" value="ALN60268"/>
        <property type="gene ID" value="GLE_4927"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4927"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4856"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595342" evidence="2">
        <location>
            <begin position="22"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="53" mass="5371" checksum="69A1A90C52968311" modified="2016-02-17" version="1">MKTLTLLFAALLLSACNPTFDRPPLLHADGAVAGKAKQGEATPPRAAAARAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNZ0</accession>
    <name>A0A0S2DNZ0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Drug:proton antiporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_03550</name>
        <name evidence="4" type="ORF">FE772_22085</name>
        <name evidence="2" type="ORF">GLE_4523</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000006">
        <property type="protein sequence ID" value="OPD65374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949120.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4523"/>
    <dbReference type="EnsemblBacteria" id="ALN59864">
        <property type="protein sequence ID" value="ALN59864"/>
        <property type="gene ID" value="GLE_4523"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65374">
        <property type="protein sequence ID" value="OPD65374"/>
        <property type="gene ID" value="BV903_03550"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4523"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4459"/>
    <dbReference type="OMA" id="VVEQDCV"/>
    <dbReference type="OrthoDB" id="1777515at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD65374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="158" mass="17626" checksum="5B0FF9FD52812186" modified="2016-02-17" version="1">MTATVTWQAKRYADLSLDELYELLQLRSQVFVIEQDCVYLDPDGKDRHPEAVHLMGRAGDGRLAAYLRILPAGLSYPQVSFGRVLTAAEFRGQRLGGPLLEAALIEIERRWPGADIQIGAQSHLQAYYGRYGFEPASEPYVEDGIPHIDLLRRGRGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP30</accession>
    <name>A0A0S2DP30_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxymuconolactone decarboxylase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_22310</name>
        <name evidence="2" type="ORF">GLE_4571</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949151.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4571"/>
    <dbReference type="EnsemblBacteria" id="ALN59912">
        <property type="protein sequence ID" value="ALN59912"/>
        <property type="gene ID" value="GLE_4571"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4571"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4507"/>
    <dbReference type="OMA" id="WREARHF"/>
    <dbReference type="OrthoDB" id="1893149at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004675">
        <property type="entry name" value="AhpD_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00778">
        <property type="entry name" value="ahpD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="17"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="152" mass="16831" checksum="0D530C02DBFF6820" modified="2016-02-17" version="1">MSARLDYNKVDPRGTQALLGLRKYIEHSGLEPSLVDLVNVRVSQINGCAYCIRAHTDEAVERGESHRRLHLLRVWPEGPFSERERAALAWAEAITHVGDPLDQAPVDDAVYARARAQFADSDLVALTYAAIAMNAWNRLAIAFRKPDPALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP96</accession>
    <name>A0A0S2DP96_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5047</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60388">
        <property type="protein sequence ID" value="ALN60388"/>
        <property type="gene ID" value="GLE_5047"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5047"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4975"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="43" mass="4776" checksum="5AFC1D5E689E31A1" modified="2016-02-17" version="1">MRVLSDRRIDGASARIAAIIARQGHPYRAATPSRFTRAEPRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPA6</accession>
    <name>A0A0S2DPA6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5039</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60380">
        <property type="protein sequence ID" value="ALN60380"/>
        <property type="gene ID" value="GLE_5039"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5039"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4967"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="38" mass="4386" checksum="2354CB29F0E85720" modified="2016-02-17" version="1">MVYRPRTVPPRMDAQQSRSRSSKVNEDDVGHGMHISYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPF8</accession>
    <name>A0A0S2DPF8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glucose-6-phosphate 1-dehydrogenase</fullName>
            <shortName evidence="5">G6PD</shortName>
            <ecNumber evidence="5">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">zwf</name>
        <name evidence="10" type="ORF">BV903_07965</name>
        <name evidence="11" type="ORF">FE772_25155</name>
        <name evidence="9" type="ORF">GLE_5193</name>
    </gene>
    <organism evidence="9 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">C3</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15841"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="1.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glucose-6-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000016">
        <property type="protein sequence ID" value="OPD64472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949623.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5193"/>
    <dbReference type="EnsemblBacteria" id="ALN60534">
        <property type="protein sequence ID" value="ALN60534"/>
        <property type="gene ID" value="GLE_5193"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64472">
        <property type="protein sequence ID" value="OPD64472"/>
        <property type="gene ID" value="BV903_07965"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5193"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5113"/>
    <dbReference type="OMA" id="WRAGHID"/>
    <dbReference type="OrthoDB" id="1153269at2"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00408"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004345">
        <property type="term" value="F:glucose-6-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00966">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019796">
        <property type="entry name" value="G6P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022675">
        <property type="entry name" value="G6P_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429">
        <property type="entry name" value="PTHR23429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02781">
        <property type="entry name" value="G6PD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00479">
        <property type="entry name" value="G6PD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000110">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00079">
        <property type="entry name" value="G6PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00871">
        <property type="entry name" value="zwf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00069">
        <property type="entry name" value="G6P_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 5" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="2 5" id="KW-0521">NADP</keyword>
    <keyword evidence="3 5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G6PD_N" evidence="7">
        <location>
            <begin position="24"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="G6PD_C" evidence="8">
        <location>
            <begin position="201"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="104"/>
            <end position="105"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="349"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN60534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD64472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW28451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="505" mass="55872" checksum="87A7A9CA46CED9DE" modified="2016-02-17" version="1">MSVYSVPSTSQPPHLAPLAPFDLVIFGGTGDLALRKLLPALFHRYADGQIVAGARIVGIARDERSDEAYRGKIREALIQFAGEQAQQTEVLDGFLALLSYRRLDLSSDSGWPEFAAEFTDAERVRVFYLAVGPDLFGVVSDRLQSHGLVNPKTRVVVEKPLGKDGVSADAINDALARVFNETQIFRIDHYLGKETVQNLTALRFSNALFEPLWKAEHIDHVQITVAETVGVESRAPYYDKSGALRDMVQNHLLQLLCLVAMEPPSSLAADAIRDEKLKVLRALRPIENGNAAAFTVRGQYKAGAVEGRAVPGYAQELGAQSLTETFVALKAEVKNWRWAGVPFYLRTGKRLAERVSEIVVTFRQVPHSIFEGLTEQDPSSRLQPNKLVLRLQPDEGVKLWLMNKVPGPGGLRLRHVPLDMSFAAAFGGRQADAYERLLMDVVRGNPMLFMRRDEVDAAWKWIDPIRAAWAASAEAPRPYTAGSWGPSAAVALIERDGRTWHEDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPL5</accession>
    <name>A0A0S2DPL5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_16690</name>
        <name evidence="5" type="ORF">D9T17_04180</name>
        <name evidence="4" type="ORF">FE772_24675</name>
        <name evidence="2" type="ORF">GLE_5092</name>
    </gene>
    <organism evidence="2 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">C3</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 9" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000044">
        <property type="protein sequence ID" value="OPD62809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000012">
        <property type="protein sequence ID" value="ROU08490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949548.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000012.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5092"/>
    <dbReference type="EnsemblBacteria" id="ALN60433">
        <property type="protein sequence ID" value="ALN60433"/>
        <property type="gene ID" value="GLE_5092"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62809">
        <property type="protein sequence ID" value="OPD62809"/>
        <property type="gene ID" value="BV903_16690"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5092"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5017"/>
    <dbReference type="OMA" id="RGRDAQW"/>
    <dbReference type="OrthoDB" id="1617768at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU08490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="118" mass="13135" checksum="82C1D7469D03D48F" modified="2016-02-17" version="1">MPADSLSTTFAALADPTRRAILARLASGEAGVTELAEPFQMSLPAISKHIKVLERAGLVARSRSAQWRPCRLETARLREVSGWLDEYRQLWDERLQRLDDYLTQLQAAPGAPHDDPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPS2</accession>
    <name>A0A0S2DPS2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter, ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_5215</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5215"/>
    <dbReference type="EnsemblBacteria" id="ALN60556">
        <property type="protein sequence ID" value="ALN60556"/>
        <property type="gene ID" value="GLE_5215"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5215"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5133"/>
    <dbReference type="OMA" id="CHNLETA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="30"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="66"/>
            <end position="73"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="252" mass="27114" checksum="61EF07BB723E75D8" modified="2016-02-17" version="1">MRPVAPVPAATVRAAAATASFYFPGRYSMIELDAVHRRYEMNGQAVNALAGVDLKIGAGEFVAITGASGSGKSSLLNILGCLDRPTRGRYLIEGRDVAEFDDEAASDIRNRRIGFVFQSFHLLPRLTVLENVLLPLRFHRQPPADAPERAQRLLARVGLGERSAHRPSELSGGQQQRAAIARALLLQPALLLADEPTGNLDSKSAADVLDLIGEVHAGGQTVVLVTHDRDLAARAPREVRLHDGKVDHDSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPS7</accession>
    <name>A0A0S2DPS7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkylhydroperoxidase AhpD core protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5269</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949680.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5269"/>
    <dbReference type="EnsemblBacteria" id="ALN60610">
        <property type="protein sequence ID" value="ALN60610"/>
        <property type="gene ID" value="GLE_5269"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5269"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5188"/>
    <dbReference type="OMA" id="SETHAPD"/>
    <dbReference type="OrthoDB" id="1893149at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004675">
        <property type="entry name" value="AhpD_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00778">
        <property type="entry name" value="ahpD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="14"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="147" mass="16265" checksum="901C028A2EA583FB" modified="2016-02-17" version="1">MSTPEAIKFEREIPQVLSQFGAAHGAVQAAADASGLPRAIYHLIQLRASQINGCAFCVKMHTREARQDGESDDRLDRLVVWRHVADFSPAERAALAWTEALTRVEDDTDYGALRAALRAHYDEAQLAAIASLAAMINLWNRLQVSKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPW8</accession>
    <name>A0A0S2DPW8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase, S54 (Rhomboid) family</fullName>
            <ecNumber evidence="8">3.4.21.-</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Rhomboid family intramembrane serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FE772_25385</name>
        <name evidence="8" type="ORF">GLE_5245</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949661.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60586">
        <property type="protein sequence ID" value="ALN60586"/>
        <property type="gene ID" value="GLE_5245"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5245"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5164"/>
    <dbReference type="OMA" id="NNPEHAM"/>
    <dbReference type="OrthoDB" id="2053476at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="7">
        <location>
            <begin position="62"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="216"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN60586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW28486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="262" mass="27930" checksum="08CFF6EC599D7993" modified="2016-02-17" version="1">MHLPTDAPIPDTPAQRKTDRARLTRALNASLAFVLALAAVYAAQGSFDIRPFTVSPWTAEGLLGLLTAPLLHGSIEHLAANATSLLLLGTLAGAVYPKATLRALPVVWLGSGLGAWLLGEPGSHHLGASGLTHGLMFLVMTLGLLRRDRPSIAAAMIAFLLYGGMLLTVLPREAGVSWQAHLGGAVAGVASAFAFRLRDPLPPRKRYSWEDEEDAELVPVNDELEPPSPRNVPVLWNRPDPGDVHSGVVLEFPRRDPPAGPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPX6</accession>
    <name>A0A0S2DPX6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5438</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60779">
        <property type="protein sequence ID" value="ALN60779"/>
        <property type="gene ID" value="GLE_5438"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5438"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5354"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="37" mass="4283" checksum="8409ABB63EF2B58D" modified="2016-02-17" version="1">MNDLASYDECENCETLPQFGLRSALKHRSRRVCADPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPX9</accession>
    <name>A0A0S2DPX9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5313</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60654">
        <property type="protein sequence ID" value="ALN60654"/>
        <property type="gene ID" value="GLE_5313"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5313"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="40" mass="4367" checksum="7BBFBF76DE1AC3A3" modified="2016-02-17" version="1">MLDGHGLGLRVMQSEKRKKREAPVRGHSRAPGVTAQRQGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ71</accession>
    <name>A0A0S2DQ71_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Biopolymer transporter ExbD</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Transport energizing protein, ExbD/TolR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FE772_25740</name>
        <name evidence="8" type="ORF">GLE_5327</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949722.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5327"/>
    <dbReference type="EnsemblBacteria" id="ALN60668">
        <property type="protein sequence ID" value="ALN60668"/>
        <property type="gene ID" value="GLE_5327"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5327"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5244"/>
    <dbReference type="OMA" id="EHAGNLP"/>
    <dbReference type="OrthoDB" id="1940365at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30558">
        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN60668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW28543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="134" mass="14022" checksum="DDB2426636748063" modified="2016-02-17" version="1">MAVTAYSPAGRFGNDTVAEINVTPLVDVMLVLLIIFMVTAPAVTGQLKLSLPVPTPAPEWTPPKAELNVQQDGSFVLDGRALTRTQLSTALTALAAENPETVLTVDANADADYQAFAQALAAADEAGIRNLSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ76</accession>
    <name>A0A0S2DQ76_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_00190</name>
        <name evidence="1" type="ORF">GLE_5381</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949764.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60722">
        <property type="protein sequence ID" value="ALN60722"/>
        <property type="gene ID" value="GLE_5381"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5381"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5296"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="146" mass="15100" checksum="8264022C4A47EA0C" modified="2016-02-17" version="1">MNEPGQSPVAPPAAAAAPPSIPAAAPSVGPVQIVDARLLQEALFAVERLLKSFVYERFVHLLTAAASSAMLLYATFKMIETGEIGSYLGQIFGASGLAALATARSAHFFKQAFDLIAGIINRMGAAQIHTVVAPNQTGAGHASRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQE3</accession>
    <name>A0A0S2DQE3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FE772_25400</name>
        <name evidence="10" type="ORF">GLE_5248</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949664.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5248"/>
    <dbReference type="EnsemblBacteria" id="ALN60589">
        <property type="protein sequence ID" value="ALN60589"/>
        <property type="gene ID" value="GLE_5248"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5248"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5167"/>
    <dbReference type="OrthoDB" id="692375at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="9">
        <location>
            <begin position="217"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="277"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN60589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW28489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="499" mass="55238" checksum="17D6DF80112841F7" modified="2016-02-17" version="1">MSAIDGRDAGTGTGDGEREARWRERERQLSSWRERCRQSREFPAGRSLRWKLTWVLFKAVLLAWFVWLSCQIWQLGREHTGMLDNSLREIAEQVLGSMPEGLDRLPSRDPARATVPVDADRKMSFQVWANGRNVVYSAAAPLQPLNPEFKDGFARRVIDGERWQVYTLTDKPRGLVVQVGRTKRMAIEELQNWIVGSLLAAALILVLFALATWLVIGRSLRPITALRRILQERQPLDLTPLPTHPLPSEFHPLVEAFNGQLERVDAAVQHERRFISDAAHELRTPLAVLSTHAELALRATTLEAKNAALQKLNAGVQRSARLSEQLLDLARLDAGEESVRLAPLDLSDLIVLVIRDFETLARERRQRISLRAEPTRLLGDVDQLGILLRNLIDNAVRHAGADGQVAVSCSAEAGGAVLRVADNGPGVATDDCERIFDRFYRAPGSPDGGSGIGLSLVARIAQTHGARIECGQGLERGGDDPRGPGRGFEVCVRFPPVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQH1</accession>
    <name>A0A0S2DQH1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase, AFG1 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_5421</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5421"/>
    <dbReference type="EnsemblBacteria" id="ALN60762">
        <property type="protein sequence ID" value="ALN60762"/>
        <property type="gene ID" value="GLE_5421"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5421"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5337"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005654">
        <property type="entry name" value="ATPase_AFG1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12169">
        <property type="entry name" value="PTHR12169"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03969">
        <property type="entry name" value="AFG1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="370" mass="41545" checksum="E4D93FBDDCE6EC27" modified="2016-02-17" version="1">MSAHPQDGAAARTPSQAYAAGVARGEWGDDPAQHPALRELDRIQAQLLGAPEPGLFDRLRGKPREGVRGLYLWGGVGRGKTFLIDLFYEQLPIAQKRRTHFHRFMREVHAQLRAHAGQSDPLAKIAREWRDTLRVLVLDEFFVIDIGDAMLLGRLLERLFAEGVTLVTTSNIDPPNLYADGLQRDRFKPAIEQIQAHCQVLLLDSQRDYRLRALTRSPVYRAPLDAESDAWLAGRWKELSAGCAPESGPLRIDDRDIAVRARADGHAWFDFAALCEGPRAASDYIEIATEYHTVLLGGIPLFDGRNDDPARRFVNLIDEFYDRHVNLVCTAADAPTGLYRGERLTGAFERTASRLIEMQSAEYLAREHRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQX3</accession>
    <name>A0A0S2DQX3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_00715</name>
        <name evidence="1" type="ORF">GLE_5500</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949851.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60841">
        <property type="protein sequence ID" value="ALN60841"/>
        <property type="gene ID" value="GLE_5500"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5500"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5415"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="135" mass="15671" checksum="252CA5C8DB89FA73" modified="2016-02-17" version="1">MVIPLIAVAKLDAQGLWLERETLIEHYLRGVNQARKLLLHPTLKSDQQLWFELGPDNAWLRVNSRTVRLWGKQRLFVASIARAHIRNQPHRRLADAVNDAGYEGDVRSLHQICSRRDFREVIGIADGFVWIRDVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-06-16" modified="2022-05-25" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>C3PTT2</accession>
    <name>C3PTT2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP-dependent oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Ox4</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Oxidoreductase, zinc-binding dehydrogenase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_15990</name>
        <name evidence="3" type="ORF">GLE_3219</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2007" name="Antimicrob. Agents Chemother." volume="51" first="64" last="72">
            <title>Structure and biosynthesis of heat-stable antifungal factor (HSAF), a broad-spectrum antimycotic with a novel mode of action.</title>
            <authorList>
                <person name="Yu F."/>
                <person name="Zaleta-Rivera K."/>
                <person name="Zhu X."/>
                <person name="Huffman J."/>
                <person name="Millet J.C."/>
                <person name="Harris S.D."/>
                <person name="Yuen G."/>
                <person name="Li X.C."/>
                <person name="Du L."/>
            </authorList>
            <dbReference type="PubMed" id="17074795"/>
            <dbReference type="DOI" id="10.1128/AAC.00931-06"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">C3</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2009-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Du L."/>
                <person name="Xie Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="3">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="EF028635">
        <property type="protein sequence ID" value="ACP19697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948132.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3219"/>
    <dbReference type="EnsemblBacteria" id="ALN58565">
        <property type="protein sequence ID" value="ALN58565"/>
        <property type="gene ID" value="GLE_3219"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3219"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3173"/>
    <dbReference type="OrthoDB" id="474248at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041694">
        <property type="entry name" value="ADH_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045010">
        <property type="entry name" value="MDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205">
        <property type="entry name" value="PTHR43205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16884">
        <property type="entry name" value="ADH_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="14"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ACP19697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="351" mass="38643" checksum="12C50E42F7E8B50E" modified="2009-06-16" version="1">MKTERWVVREHVEGVPDAARIYEKVETELNTRLGEEQMLLKTLYVSVDPYLQGICLDTPIGDHMGADSIMQVLDAGPNAPFRPGDLVQGFGGWRTHLVSDGKPKLWQTGTFPMVFPAYRKLDLRHYDDALPLSTALGVMGGPGMTAWGTMTKFMQVRPGDTVVVSGASGMIGTLVGQMAKRAGARVVGTAGSAGKARYLSQLGFDAVIDYKLADDADKMREALREAAPDGVDKYFDSIGGSVTDAVFSMLNVGSQVAVCWQWATQVQRDYHGPRLLPYIMFPRATIRGIFSLEWFTEQNWSALHEELGGLVRRQELVAHETVQDGFEHIPAAYQTLFSASESNRGKVLVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA20</accession>
    <name>A0A0S2DA20_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0028</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55387">
        <property type="protein sequence ID" value="ALN55387"/>
        <property type="gene ID" value="GLE_0028"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0028"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.35"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="59" mass="7007" checksum="826C1D3C647900B3" modified="2016-02-17" version="1">MQDRYPNRDGIYTKLRELTAADLDAQIRVLQELAVQHEEHVQALIAYRDRVFDKSRHGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA56</accession>
    <name>A0A0S2DA56_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative comF family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">comF</name>
        <name evidence="3" type="ORF">GLE_0060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0060"/>
    <dbReference type="EnsemblBacteria" id="ALN55419">
        <property type="protein sequence ID" value="ALN55419"/>
        <property type="gene ID" value="GLE_0060"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0060"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.66"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044005">
        <property type="entry name" value="DZR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18912">
        <property type="entry name" value="DZR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DZR_2" evidence="2">
        <location>
            <begin position="22"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="350" mass="37032" checksum="90C1B281C9E79709" modified="2016-02-17" version="1">MNPDTFALACPAGFWSRLGWSLWPARCLACAEPGLPGCDLCATCWTHWPRTGRSCLGCAMPLPVDVAGETEVAVARVRDGGSDADRGAALDAGPDIALDANLDTDLEADRWHPADSAPRAADMPRDRCGACRNRASPLHEVRAAAFYRAPLDRLLPRFKFHRDLAAGRLLASTMAAAFAPRAASLLANGAAATPRQSAAQASERPNAPGAPGAPGATGATGEPGRRTATTAARDIPTLVPIPLHRGRLRERGYDQALELARPLSRRLGLALCATGLHRLRATPAQSRLDAARRRRNLRDAFAWTGAAAPPMHAILIDDVMTTGATLHAAALALRRAGAQRVDAWVCARAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAB2</accession>
    <name>A0A0S2DAB2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RDD family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_0125</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945813.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0125"/>
    <dbReference type="EnsemblBacteria" id="ALN55484">
        <property type="protein sequence ID" value="ALN55484"/>
        <property type="gene ID" value="GLE_0125"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0125"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.128"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010432">
        <property type="entry name" value="RDD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06271">
        <property type="entry name" value="RDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="RDD" evidence="6">
        <location>
            <begin position="7"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN55484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="231" mass="24192" checksum="21578E2D4BC6DE1E" modified="2016-02-17" version="1">MNAPGAPAGFWPRYLAWSLDAALVALATCLLGANHWRLLIAAAARAWDALNQRVADAMAASALDDLAFGGFLGRLGADPQVHAAAAAAIAALLSLVLGWLMVYAVLGFALEVACIAFTSWRATPGKRALGLYVAARDGGELGAGRAALRYLGGSLSWLSFNIGHLVAMAKPEHLALHDRLAGASVRRRGGAGLPPWGWAWLLLQLAAALAACVWLAWTMQASLDEALYAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAC0</accession>
    <name>A0A0S2DAC0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glycine--tRNA ligase beta subunit</fullName>
            <ecNumber evidence="10">6.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Glycyl-tRNA synthetase beta subunit</fullName>
            <shortName evidence="10">GlyRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 12" type="primary">glyS</name>
        <name evidence="13" type="ORF">FE772_01560</name>
        <name evidence="12" type="ORF">GLE_0129</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">C3</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly)</text>
            <dbReference type="Rhea" id="RHEA:16013"/>
            <dbReference type="Rhea" id="RHEA-COMP:9664"/>
            <dbReference type="Rhea" id="RHEA-COMP:9683"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.14"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4 10">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945816.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0129"/>
    <dbReference type="EnsemblBacteria" id="ALN55488">
        <property type="protein sequence ID" value="ALN55488"/>
        <property type="gene ID" value="GLE_0129"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0129"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.132"/>
    <dbReference type="OMA" id="LPIPKRM"/>
    <dbReference type="OrthoDB" id="213210at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006426">
        <property type="term" value="P:glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00255">
        <property type="entry name" value="Gly_tRNA_synth_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015944">
        <property type="entry name" value="Gly-tRNA-synth_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006194">
        <property type="entry name" value="Gly-tRNA-synth_heterodimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30075">
        <property type="entry name" value="PTHR30075"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02092">
        <property type="entry name" value="tRNA_synt_2f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01045">
        <property type="entry name" value="TRNASYNTHGB"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00211">
        <property type="entry name" value="glyS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50861">
        <property type="entry name" value="AA_TRNA_LIGASE_II_GLYAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DALR_1" evidence="11">
        <location>
            <begin position="588"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN55488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW24555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="696" mass="75680" checksum="1FB8F436CFEBC0C9" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAR5</accession>
    <name>A0A0S2DAR5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Cytochrome c oxidase subunit 2</fullName>
            <ecNumber evidence="14">7.1.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">ccoO</name>
        <name evidence="21" type="synonym">coxB</name>
        <name evidence="22" type="ORF">D9T17_01445</name>
        <name evidence="21" type="ORF">FE772_02260</name>
        <name evidence="20" type="ORF">GLE_0286</name>
    </gene>
    <organism evidence="20 23">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="20 23" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 23">C3</strain>
        </source>
    </reference>
    <reference evidence="22 24" key="2">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 24">OH11</strain>
        </source>
    </reference>
    <reference evidence="21 25" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 25">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 14">Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>4 Fe(II)-[cytochrome c] + 8 H(+)(in) + O2 = 4 Fe(III)-[cytochrome c] + 4 H(+)(out) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11436"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="7.1.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="14">Binds a copper A center.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the cytochrome c oxidase subunit 2 family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.9" evidence="14"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000004">
        <property type="protein sequence ID" value="ROU09090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945928.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0286"/>
    <dbReference type="EnsemblBacteria" id="ALN55644">
        <property type="protein sequence ID" value="ALN55644"/>
        <property type="gene ID" value="GLE_0286"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0286"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.285"/>
    <dbReference type="OMA" id="HAFMPIA"/>
    <dbReference type="OrthoDB" id="1654242at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070469">
        <property type="term" value="C:respirasome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045187">
        <property type="entry name" value="CcO_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002429">
        <property type="entry name" value="CcO_II-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001505">
        <property type="entry name" value="Copper_CuA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014222">
        <property type="entry name" value="Cyt_c_oxidase_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011759">
        <property type="entry name" value="Cyt_c_oxidase_su2_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036257">
        <property type="entry name" value="Cyt_c_oxidase_su2_TM_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22888">
        <property type="entry name" value="PTHR22888"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00116">
        <property type="entry name" value="COX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02790">
        <property type="entry name" value="COX2_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81464">
        <property type="entry name" value="SSF81464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02866">
        <property type="entry name" value="CoxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00078">
        <property type="entry name" value="COX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50857">
        <property type="entry name" value="COX2_CUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50999">
        <property type="entry name" value="COX2_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14" id="KW-0186">Copper</keyword>
    <keyword evidence="8 13" id="KW-0249">Electron transport</keyword>
    <keyword evidence="11 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="17" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 13 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242127" description="Cytochrome c oxidase subunit 2" evidence="17">
        <location>
            <begin position="27"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="50"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="COX2_TM" evidence="19">
        <location>
            <begin position="28"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="COX2_CUA" evidence="18">
        <location>
            <begin position="125"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="271"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ALN55644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="QCW24668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="ROU09090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="316" mass="33867" checksum="A7ABE383F562A34C" modified="2016-02-17" version="1">MKAGRFKQWAAGVAAMALPVLAFAQAADPKPWQLNMGKGVTAQSMNAHSAHMLALWICVVIGILVFGAMAVAMFKFRKSKGAVPDKDFVHSTKLEIVWTVVPVALLVLMAFPATSKLINMYDTRDSAMTVKITGIQWLWKYEYLGEGVAITSRLDRKSDQLRQSGKHVTAADHEHYLLDVDNVLVLPTDTKIRFVITADDVIHAWWVPALGWKQDAIPGIVNEAWTDIKEPGIYRGQCAELCGKDHGFMPIVVRAVPKAEYQQWLAEQKAKNAPAPAPAAAPAAAPAAPAAAQAQPAGTASSDAPAAAPKGAATAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB43</accession>
    <name>A0A0S2DB43_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55738">
        <property type="protein sequence ID" value="ALN55738"/>
        <property type="gene ID" value="GLE_0380"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0380"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.377"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="49" mass="5163" checksum="066F508CCC316E6D" modified="2016-02-17" version="1">MPSASRIFRAHDSGSMASTRAPDACLRRRRLPRSGAAGRDGGDAGRVAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBF0</accession>
    <name>A0A0S2DBF0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Efflux pump membrane transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_03230</name>
        <name evidence="7" type="ORF">GLE_0498</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cell inner membrane</location>
            <topology evidence="2 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55856">
        <property type="protein sequence ID" value="ALN55856"/>
        <property type="gene ID" value="GLE_0498"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0498"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.493"/>
    <dbReference type="OMA" id="TLFGAQH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042908">
        <property type="term" value="P:xenobiotic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004764">
        <property type="entry name" value="HAE1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00915">
        <property type="entry name" value="2A0602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="394"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="440"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="468"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="554"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="888"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="912"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="938"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="982"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1015"/>
            <end position="1041"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN55856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW24834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="1062" mass="113282" checksum="4EB30134039508C8" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBM6</accession>
    <name>A0A0S2DBM6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Lipocalin-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_03300</name>
        <name evidence="3" type="ORF">GLE_0515</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946090.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0515"/>
    <dbReference type="EnsemblBacteria" id="ALN55873">
        <property type="protein sequence ID" value="ALN55873"/>
        <property type="gene ID" value="GLE_0515"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0515"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.510"/>
    <dbReference type="OMA" id="PNWNGVE"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024311">
        <property type="entry name" value="Lipocalin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13924">
        <property type="entry name" value="Lipocalin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242274" evidence="1">
        <location>
            <begin position="33"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Lipocalin-like" evidence="2">
        <location>
            <begin position="39"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="172" mass="18586" checksum="43E559DE5787FB6C" modified="2016-02-17" version="1">MPRLCSALFANAFFAIAFLAVAWLAAASPAAAADSASLVGTWRVERIVDTDAAGKRHYPYGEKPKGYIVYDPSGHLHVQIMRTPAPPPFAAGDDAKGSDAETRAAFLGYAAYFGTYRVDAAKGVVVHRVEGSLMPSYTGTDQPRPFRIDGDVLTIEGDSEGVHFVRQLRRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC52</accession>
    <name>A0A0S2DC52_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD(+) diphosphatase</fullName>
            <ecNumber evidence="2">3.6.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLE_0729</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.22" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0729"/>
    <dbReference type="EnsemblBacteria" id="ALN56087">
        <property type="protein sequence ID" value="ALN56087"/>
        <property type="gene ID" value="GLE_0729"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0729"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.717"/>
    <dbReference type="OMA" id="HIRRCPA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000210">
        <property type="term" value="F:NAD+ diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015375">
        <property type="entry name" value="NADH_PPase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015376">
        <property type="entry name" value="Znr_NADH_PPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09296">
        <property type="entry name" value="NUDIX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09297">
        <property type="entry name" value="zf-NADH-PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="8">
        <location>
            <begin position="173"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="321" mass="35075" checksum="FBC6B711E47460B4" modified="2016-02-17" version="1">MNTAEAALSQAARPFAFVEADAAWRAALDRADHLRTQPEALSELWPQARIVVLDASGNALADDDGALRAPLGRELSDGPGGPGAAIFLGLDGEGGAWFAIDAELVAFDAPRRVDLRAAAAHWPLLHASVFAQARALQFWRNRNRFCGVCGGAVGFERAGWMGRCGQCGTEHYPRTDPAVIVAVSDGERLLLGRQAAWPPRRFSVIAGFVEPGESLEQTVAREVLEETGVRVRDCRYLGSQPWPFPGALMLGFEARAEAGEPHSSEELEEVRWFTLEEIRAAIARGERGADDGEGYLLSPSISISRWLIEHWRLAAEERLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC79</accession>
    <name>A0A0S2DC79_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0764</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56122">
        <property type="protein sequence ID" value="ALN56122"/>
        <property type="gene ID" value="GLE_0764"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0764"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.752"/>
    <dbReference type="OMA" id="FCANGGI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="344" mass="36674" checksum="6D90C871C43CA021" modified="2016-02-17" version="1">MSDACPSACPQDPRLPSRAGARMSARGLAMAAAAALLGGALVYAYAHRGAAGSAPAALSDIVAAPMAGDLPRGNPQADPAREPPIRIAPRRDARAPLRAPTALRQQFEQTPDLYSFAQSLRLRAESGEAEAIWLLTRVYDYCANYSSAPVDYRNDTRAMEAMKLRGAAAMASARNRVSERCARFAPEDGLDYPMILVKRVEAAQAGSLAAEASLMSAGKPLEKTEDYRLNLIDRVVRSKDPEAFSALAAGMGIATNGRSAGFDYQRVSGTQFAELAWQLAACRLGQDCSAGGSLMTSYCANGGICSQDPQQDFADFVYDAAIPRQGAEVVQEMVHSLTGEERMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCG9</accession>
    <name>A0A0S2DCG9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0862</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56220">
        <property type="protein sequence ID" value="ALN56220"/>
        <property type="gene ID" value="GLE_0862"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0862"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.851"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="59" mass="5946" checksum="6AF01F30BABA2DFE" modified="2016-02-17" version="1">MCSAWGCVQADGNGNGNGNGNGSSTVEMDSGWRRIGVGSQGHGESEFGHALRPATARPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCJ8</accession>
    <name>A0A0S2DCJ8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0893</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56251">
        <property type="protein sequence ID" value="ALN56251"/>
        <property type="gene ID" value="GLE_0893"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0893"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046116">
        <property type="entry name" value="DUF6053"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19523">
        <property type="entry name" value="DUF6053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="43" mass="4108" checksum="E69EBBB2CFA18D53" modified="2016-02-17" version="1">MAAAAERARRILSAFGGGPAGPDALALVGGPSGPMLSFPIAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCU2</accession>
    <name>A0A0S2DCU2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0974</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56332">
        <property type="protein sequence ID" value="ALN56332"/>
        <property type="gene ID" value="GLE_0974"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0974"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.961"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="82" mass="8564" checksum="D4AF9735B9BA47CE" modified="2016-02-17" version="1">MPPRARSVGALAGCRARRKVPARAAPRMAPKRSDATVAPSCRDTGRSSPEDSIGPGPRGCATRGCRQVFGLGTQSQKQSGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCV9</accession>
    <name>A0A0S2DCV9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1019</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946465.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56377">
        <property type="protein sequence ID" value="ALN56377"/>
        <property type="gene ID" value="GLE_1019"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1019"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1007"/>
    <dbReference type="OrthoDB" id="2203776at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="222" mass="22941" checksum="F2BB4EF4ABE00D78" modified="2016-02-17" version="1">MQAEQSTPVAPAVRAGAAREVSRGESVLAWTAVVAFHAALFWLAGKALMPRSAAVDAHALTLVWLPPPAEPAPREPAAAPPVNPPARAQPASRHRAPPARIPADAADPTTDAGLTAVAIGPAPPVPVAPAATATRAPWDAPPSPPAKPFARRAPDLPGQGAQRFRMRPPRSIASTVGQIGLLFGGGGPSDCAETRKNIRDLAVLGAEAVAQEVEEERRNCRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD18</accession>
    <name>A0A0S2DD18_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">YecA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0895</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0895"/>
    <dbReference type="EnsemblBacteria" id="ALN56253">
        <property type="protein sequence ID" value="ALN56253"/>
        <property type="gene ID" value="GLE_0895"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0895"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.884"/>
    <dbReference type="OMA" id="WVNHFIS"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011978">
        <property type="entry name" value="UPF0149"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036255">
        <property type="entry name" value="YgfB-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03695">
        <property type="entry name" value="UPF0149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101327">
        <property type="entry name" value="SSF101327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="174" mass="17999" checksum="65C39CCBAAF09D10" modified="2016-02-17" version="1">MSEVEAESLALTLSTSAAELHGALCGWLAGGGADVREWPARVLADPAAATPAAGGALDRLRATTVAQIGDAEFGFELLLPDAQASLSERSGALFDWCRGFLGGFGLAAGAAPNLSEESREALGDLAKFAATAPQEEGDEEDEEALAELEEFVRVAALGLHGDVALAARHRQRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD42</accession>
    <name>A0A0S2DD42_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amino acid racemase</fullName>
            <ecNumber evidence="3">5.1.1.-</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Aspartate racemase</fullName>
            <ecNumber evidence="2">5.1.1.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_05815</name>
        <name evidence="2" type="ORF">GLE_1045</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aspartate/glutamate racemases family.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.-" evidence="3"/>
    <dbReference type="EC" id="5.1.1.13" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946486.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1045"/>
    <dbReference type="EnsemblBacteria" id="ALN56403">
        <property type="protein sequence ID" value="ALN56403"/>
        <property type="gene ID" value="GLE_1045"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1045"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1034"/>
    <dbReference type="OMA" id="AECLLMC"/>
    <dbReference type="OrthoDB" id="1359310at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047689">
        <property type="term" value="F:aspartate racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015942">
        <property type="entry name" value="Asp/Glu/hydantoin_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001920">
        <property type="entry name" value="Asp/Glu_race"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033134">
        <property type="entry name" value="Asp/Glu_racemase_AS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004380">
        <property type="entry name" value="Asp_race"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21198:SF7">
        <property type="entry name" value="PTHR21198:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01177">
        <property type="entry name" value="Asp_Glu_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53681">
        <property type="entry name" value="SSF53681"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00035">
        <property type="entry name" value="asp_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00924">
        <property type="entry name" value="ASP_GLU_RACEMASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="234" mass="25088" checksum="AF6115137685B03D" modified="2016-02-17" version="1">MTAPLPLGIVACSSEGAALCYRTICAEAAALLGPHAHPDIALHGHSLADYVACLERGDLDGVGELMLASARKLERAGAKLLICPDNTIHQAMDYVRPRSPLPWLHIAEVVAREAQARGFRRIGLTGTQWLVESEVYPRQLAALGLEYVRPGAEQRARIGRLIMDELVYGVFKPETVAYFQGVIEDLKAQGCDAVVLGCTEIPLIIDDGNSALPTLDSTRLLARAALRAAVAGVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD60</accession>
    <name>A0A0S2DD60_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_05895</name>
        <name evidence="2" type="ORF">GLE_1065</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1065"/>
    <dbReference type="EnsemblBacteria" id="ALN56423">
        <property type="protein sequence ID" value="ALN56423"/>
        <property type="gene ID" value="GLE_1065"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1065"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1053"/>
    <dbReference type="OMA" id="DDSPRYE"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033243121" evidence="1">
        <location>
            <begin position="24"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="318" mass="36062" checksum="EE20ACF6DB68BC99" modified="2016-02-17" version="1">MNLRNFRASVLAISLFSSLSAMAQTAAAPAADPVRDRASILAMQGEYIVDFAFDETVLLKPGYERAPAMRSGGNETVIVVEDTPTKLVLQHILVDGKSGHVTKHWRQDWTFEAPQRFEFSADQTWHVRAIPAELNRGAWTQCVYEVSDAPRYCGTGRWDYAHGNATWTSDPSWRPLPRREYTKRSDYNAIVAINRHTLTPNGWTHEQFNTKVLRKPDGSQQELAREFGFNDYVKTKDIDFKPAYTYWQATQGYWAKVRQRWDAYLGKAPGVRLKTKVDGMAMIIPLFEQAGKLEEGKKVADKDIDAVFAKWVVAAPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD73</accession>
    <name>A0A0S2DD73_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 9">Uroporphyrinogen decarboxylase</fullName>
            <shortName evidence="8">UPD</shortName>
            <shortName evidence="8">URO-D</shortName>
            <ecNumber evidence="4 8 9">4.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 13" type="primary">hemE</name>
        <name evidence="14" type="ORF">BV903_16190</name>
        <name evidence="15" type="ORF">FE772_06260</name>
        <name evidence="13" type="ORF">GLE_1147</name>
    </gene>
    <organism evidence="13 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">C3</strain>
        </source>
    </reference>
    <reference evidence="14 17" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">B25</strain>
        </source>
    </reference>
    <reference evidence="15 18" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 18">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>4 H(+) + uroporphyrinogen III = 4 CO2 + coproporphyrinogen III</text>
            <dbReference type="Rhea" id="RHEA:19865"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="EC" id="4.1.1.37"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8 9">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 10">Belongs to the uroporphyrinogen decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.37" evidence="4 8 9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000043">
        <property type="protein sequence ID" value="OPD62824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946552.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1147"/>
    <dbReference type="EnsemblBacteria" id="ALN56505">
        <property type="protein sequence ID" value="ALN56505"/>
        <property type="gene ID" value="GLE_1147"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62824">
        <property type="protein sequence ID" value="OPD62824"/>
        <property type="gene ID" value="BV903_16190"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1147"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1132"/>
    <dbReference type="OMA" id="LWLMRQA"/>
    <dbReference type="OrthoDB" id="1104410at2"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00321"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004853">
        <property type="term" value="F:uroporphyrinogen decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00717">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00218">
        <property type="entry name" value="URO_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006361">
        <property type="entry name" value="Uroporphyrinogen_deCO2ase_HemE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000257">
        <property type="entry name" value="Uroporphyrinogen_deCOase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01208">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="SSF51726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01464">
        <property type="entry name" value="hemE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00906">
        <property type="entry name" value="UROD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00907">
        <property type="entry name" value="UROD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8 9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6 8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 8 9" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uroporphyrinogen_deCOase" evidence="11">
        <location>
            <begin position="24"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="Uroporphyrinogen_deCOase" evidence="12">
        <location>
            <begin position="144"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="29"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS00907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN56505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OPD62824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW25323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="358" mass="38863" checksum="34C50B9E825A9CFE" modified="2016-02-17" version="1">MSSQPLANDRFLRALRRQPVDRTPVWLMRQAGRYLPEYRATRAQAGSFLQLAKNPELACEVTLQPLRRFPLDAAILFSDILTVPDAMGLGLYFADGEGPKFERPIRSAADIDKLGVPDMETDLRYVMDAVRTIRRELNGSVPLIGFSGSPWTIACYMVEGGGSDNYSKVKSLALNDPAAMHKLLGTVTDAVIAYLKAQHAAGAQALQVFDTWGGVLSPSMYREFSLRYLQRIAAELPRGDGETRAPLILFGKGNDPYLDELAASGAEAVGVDWTIGLGDAARRIGGRTALQGNLDPVTLYASPEAIRREVGRALDDYRDGNGGSREGHVFNLGHGLSPDMSPEHVGALVAAVHELSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD97</accession>
    <name>A0A0S2DD97_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Xanthine dehydrogenase family protein molybdopterin-binding subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_06195</name>
        <name evidence="2" type="ORF">GLE_1132</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946545.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1132"/>
    <dbReference type="EnsemblBacteria" id="ALN56490">
        <property type="protein sequence ID" value="ALN56490"/>
        <property type="gene ID" value="GLE_1132"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1132"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1117"/>
    <dbReference type="OMA" id="ANDRYEQ"/>
    <dbReference type="OrthoDB" id="117507at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11908">
        <property type="entry name" value="PTHR11908"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="Ald_Xan_dh_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54665">
        <property type="entry name" value="SSF54665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="SSF56003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ald_Xan_dh_C2" evidence="1">
        <location>
            <begin position="262"/>
            <end position="878"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="952" mass="103197" checksum="23983AFB02926AA2" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDE0</accession>
    <name>A0A0S2DDE0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sulfate adenylyltransferase subunit 2</fullName>
            <ecNumber evidence="2">2.7.7.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">ATP-sulfurylase small subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Sulfate adenylate transferase</fullName>
            <shortName evidence="2">SAT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 5" type="primary">cysD</name>
        <name evidence="6" type="ORF">FE772_06690</name>
        <name evidence="5" type="ORF">GLE_1237</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + H(+) + sulfate = adenosine 5'-phosphosulfate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:18133"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="EC" id="2.7.7.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer composed of CysD, the smaller subunit, and CysN.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the PAPS reductase family. CysD subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.4" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1237"/>
    <dbReference type="EnsemblBacteria" id="ALN56594">
        <property type="protein sequence ID" value="ALN56594"/>
        <property type="gene ID" value="GLE_1237"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1237"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1221"/>
    <dbReference type="OMA" id="MMILAED"/>
    <dbReference type="UniPathway" id="UPA00140">
        <property type="reaction ID" value="UER00204"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004781">
        <property type="term" value="F:sulfate adenylyltransferase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070814">
        <property type="term" value="P:hydrogen sulfide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019419">
        <property type="term" value="P:sulfate reduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01713">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00064">
        <property type="entry name" value="Sulf_adenylyltr_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011784">
        <property type="entry name" value="SO4_adenylTrfase_ssu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002936">
        <property type="entry name" value="CysDAde_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02039">
        <property type="entry name" value="CysD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAPS_reduct" evidence="4">
        <location>
            <begin position="48"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW25394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="321" mass="36386" checksum="6122ECEED67B3B4E" modified="2016-02-17" version="1">MSASPVPSAAFDPVSDTSTPLAQALSHLDRLEAESIHILREVAAEFRNPVMLYSIGKDSSVLLHLLLKAFYPARPPIPLLHVDTGWKFREMIAFRDRRAAETGVDLRVHMNPDGLAQGIGPVSHGAAVHTDVMKTQGLKQALDWNKFDAAIGGARRDEEKSRAKERIFSFRNPQHRWDPKNQRPELWNLYNTRIHAGESVRVFPISNWTELDVWLYIFRERIPVPSLYFAAKRPVVERDGALILVDDERLPLRAGETPQVRNVRFRTLGCYPLTGAIESEADTLEKIIAEMLVATTSERQGRMIDHDPSASMERKKQEGYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDK3</accession>
    <name>A0A0S2DDK3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9 11">FAD:protein FMN transferase</fullName>
            <ecNumber evidence="3 9 11">2.7.1.180</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Flavin transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLE_1244</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9 11">
            <text>FAD + L-threonyl-[protein] = AMP + FMN-L-threonyl-[protein] + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36847"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11061"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:74257"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.1.180"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="10">Magnesium. Can also use manganese.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 11">Belongs to the ApbE family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.180" evidence="3 9 11"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1244"/>
    <dbReference type="EnsemblBacteria" id="ALN56601">
        <property type="protein sequence ID" value="ALN56601"/>
        <property type="gene ID" value="GLE_1244"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1244"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1228"/>
    <dbReference type="OMA" id="MGTYYSI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017013">
        <property type="term" value="P:protein flavinylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024932">
        <property type="entry name" value="ApbE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003374">
        <property type="entry name" value="ApbE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30040">
        <property type="entry name" value="PTHR30040"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02424">
        <property type="entry name" value="ApbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006268">
        <property type="entry name" value="ApbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143631">
        <property type="entry name" value="SSF143631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 9 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11 13" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8 9 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9 11" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="287"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="336"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR006268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006268-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN56601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="386" mass="40463" checksum="4D4ED73D3323C513" modified="2016-02-17" version="1">MAVRAPQPMWSWTGAVAPAHGAGVGARDPLATGAFAPTYSANFAASTTLDATAMSAPAALHELRGLSMGTTWSVKLVAPVSALIGLERGIQAMLDEVVAQMSTWETDSDISRYNHAAAGSTHVLPAPFAEVLHAALALAADTDGAYDPTIGPLADLWGFGPAGARTQAPAAAPLAQARERVDWRRLHFDPARHELFQPGGAYLDFSSIAKGYGVDRVADWLLAHGVADCLVEVGGELRAHGRKPDGSAWRIAVEQPGREDEAAAVIALDNLSIATSGDYRRYFEPSGFEHTGGERSGAPTGGARRYSHTLDPRTGAPIDNAVASVTVVHERCMHADALATALTVLGARAGLAYANRCQLAALFVLREGEGFVARATPGFVARQRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDS5</accession>
    <name>A0A0S2DDS5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aspartyl/Asparaginyl beta-hydroxylase family</fullName>
            <ecNumber evidence="3">1.14.11.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1103</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.14.11.16" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56461">
        <property type="protein sequence ID" value="ALN56461"/>
        <property type="gene ID" value="GLE_1103"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1103"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1090"/>
    <dbReference type="OMA" id="LIFDVWN"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062101">
        <property type="term" value="F:peptidyl-aspartic acid 3-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018193">
        <property type="term" value="P:peptidyl-amino acid modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007803">
        <property type="entry name" value="Asp/Arg/Pro-Hydrxlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05118">
        <property type="entry name" value="Asp_Arg_Hydrox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="123"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Asp_Arg_Hydrox" evidence="2">
        <location>
            <begin position="318"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="507" mass="57647" checksum="1B8908BD2EE042BD" modified="2016-02-17" version="1">MPYRPPRRVRAPWLRSPIRRFADSPIRRFADSVVCWFAAPPRRRAYEPISGQADPLAARAARYAKRARRCMVWPITITRGRGAVLSEQVNQLVQAAGLASRAGRWQEAERLWQQVRALAPQHPQALYSLGVHALQRGDAQGAIELLQAAHRAAPRDPMILLSIGMVERERGNLQAESEAIQAALALDPYFLAGLLAKASWLERQGQARAAAQAWRNALTVAPPQPHWPDMLRSQLEHAQRKVEEYRDEFAAFLEHRVGGTREALEFGARGRWQEAASIMVGRSTPYLSQSNQLCVPRLPAIPFFEREQFAWAPELESRTHDILREMRQALRDEQAEFTPYIEYQPGDPVNQWRELNHSRRWSTYKLWSYSQPVDAHLARCPATRAALEAVDMADIADVCPNAMFSALAPHTHIPPHHGETNARLVAHLPLIVPEKCSYRVGFERREWKVGETLIFDDSIEHEARNDSDDLRVVLIFDVWNPLLSLAERAMVDAMMAAHREFLAGAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDW2</accession>
    <name>A0A0S2DDW2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bifunctional nicotinamide-nucleotide adenylyltransferase/Nudix hydroxylase</fullName>
            <ecNumber evidence="4">2.7.7.1</ecNumber>
            <ecNumber evidence="4">3.6.1.-</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="3">MutT/nudix family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_07335</name>
        <name evidence="3" type="ORF">GLE_1384</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.1" evidence="4"/>
    <dbReference type="EC" id="3.6.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946735.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1384"/>
    <dbReference type="EnsemblBacteria" id="ALN56741">
        <property type="protein sequence ID" value="ALN56741"/>
        <property type="gene ID" value="GLE_1384"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1384"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1366"/>
    <dbReference type="OMA" id="YPPVFVT"/>
    <dbReference type="OrthoDB" id="1846332at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000309">
        <property type="term" value="F:nicotinamide-nucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="212"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="352" mass="39252" checksum="1B0BFAFDD81A8638" modified="2016-02-17" version="1">MALQQYDYLVFIGRFEPFHNGHAAVARHALGKAAKVVFLVGSADTPRTVKNPFTVAERAVMIQAALADSADRLIVRPLRDHLYNESQWIANVQRSVAEAVRADGGAADARIGLIGMDKDASSYYLREFPQWPLVDVNHTATLSATELRKYLFEANQLDSHGGLMLIRANVPAPVFDMLEAFRKSSPAFKQLVAEYQFIEQYRAAWADAPYAPTFVTTDAVVVHSGHVLLVRRRAEPGKGLWALPGGFVGQHESLLDACLRELREETRLKVPLAVLKGSIKGERVFDHPERSARGRTITHAFHFDFPAGELPQVRGGDDADKARWFPVSEALEMSPQLFEDHLHILEYFLGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDX8</accession>
    <name>A0A0S2DDX8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56659">
        <property type="protein sequence ID" value="ALN56659"/>
        <property type="gene ID" value="GLE_1302"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1302"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1285"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="44" mass="4658" checksum="B3551DC93055C969" modified="2016-02-17" version="1">MNEAARQGMAHIRGSVQTSEAAPPPVCRSRPRIPATVAARFATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE09</accession>
    <name>A0A0S2DE09_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_07315</name>
        <name evidence="2" type="ORF">GLE_1380</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946732.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1380"/>
    <dbReference type="EnsemblBacteria" id="ALN56737">
        <property type="protein sequence ID" value="ALN56737"/>
        <property type="gene ID" value="GLE_1380"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1380"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1362"/>
    <dbReference type="OrthoDB" id="1027546at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016977">
        <property type="term" value="F:chitosanase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009939">
        <property type="entry name" value="Chitosanase_fungal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07335">
        <property type="entry name" value="Glyco_hydro_75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="247" mass="26088" checksum="BAA8903C285F2EE6" modified="2016-02-17" version="1">MGVVLIEHWTEFAGAALHRVDAGGHRAYAFLCAGPPITAQGAPDAYHPDDTGSGSLHDSGWPSGAWRERLVPDPHQPQRPLRQSEGAQAGYFVSTTALADARFPRSNPQAYVDAGRVPYLAMPATWLAQAGAGGVGDFVVVHDRATARSSFGLIGDAGRGRALGEMSERMASDLSGVRAHARSGRGAPQGTLLCVVFPGSRREPAWPLRNSALRSRCEQLLRPLGGVARLAQLADSLAGLPASRPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE31</accession>
    <name>A0A0S2DE31_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chromosome partitioning protein ParB</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">RepB plasmid partitioning protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_07635</name>
        <name evidence="3" type="ORF">GLE_1452</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946785.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1452"/>
    <dbReference type="EnsemblBacteria" id="ALN56809">
        <property type="protein sequence ID" value="ALN56809"/>
        <property type="gene ID" value="GLE_1452"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1452"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1432"/>
    <dbReference type="OMA" id="HKMIRKA"/>
    <dbReference type="OrthoDB" id="1630210at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB/Sulfiredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011111">
        <property type="entry name" value="Plasmid_RepB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02195">
        <property type="entry name" value="ParBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07506">
        <property type="entry name" value="RepB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ParB" evidence="1">
        <location>
            <begin position="35"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="RepB" evidence="2">
        <location>
            <begin position="111"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="323" mass="36013" checksum="78D3DB7A7078857F" modified="2016-02-17" version="1">MNDDTTKDDADDVPKQTFSSKCVRLELSQLIALKPVKPEIRRAMKFRQILTSVREVGLVEPPVVKQAPHKKGSYFILDGHLRIEALRELDVQHVDCLVALEDDTYSYNKHVNRASAIQNHRMIAQAANNGASPERLAQALGMSTASVRKKFTLLKGICDEVAELLADTNCPQKTFDVLRRMKPVRQIEAAELMVGNRDFTTVFAKAMLLTTPPEQLVDPEGRYNKAAGVGQMAGLERELVMLQSRAKILEDTYSDDLMVLTVTKGYLSTLLGDAKIVRWLTKQHPEYLKEFERIVDMDSLPGIARTSGNGARLASSKLIHPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEA7</accession>
    <name>A0A0S2DEA7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_06900</name>
        <name evidence="1" type="ORF">GLE_1614</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000013">
        <property type="protein sequence ID" value="OPD64616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1614"/>
    <dbReference type="EnsemblBacteria" id="ALN56971">
        <property type="protein sequence ID" value="ALN56971"/>
        <property type="gene ID" value="GLE_1614"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64616">
        <property type="protein sequence ID" value="OPD64616"/>
        <property type="gene ID" value="BV903_06900"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1614"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1594"/>
    <dbReference type="OMA" id="YAERRIS"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD64616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="144" mass="15872" checksum="513FDA02701E912A" modified="2016-02-17" version="1">MFVLCASAKAQEAPSAEPAQGNCPLLPASTGLHWEYRGTADSDFCRALREDGSEAFGLYIADKSPFQPRRGDRVEEATIDGKQIHWYRSQIAGKPDVQARETLIEVGNGKLAHIWVQAQSADQLKEALGQTEGLRFQSARLSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEE2</accession>
    <name>A0A0S2DEE2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">M20/M25/M40 family metallo-hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Peptidase M28</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Peptidase, M28 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_21840</name>
        <name evidence="4" type="ORF">FE772_07985</name>
        <name evidence="2" type="ORF">GLE_1524</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000072">
        <property type="protein sequence ID" value="OPD61819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946848.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000072.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1524"/>
    <dbReference type="EnsemblBacteria" id="ALN56881">
        <property type="protein sequence ID" value="ALN56881"/>
        <property type="gene ID" value="GLE_1524"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61819">
        <property type="protein sequence ID" value="OPD61819"/>
        <property type="gene ID" value="BV903_21840"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1524"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1506"/>
    <dbReference type="OMA" id="PFWDAGY"/>
    <dbReference type="OrthoDB" id="1465483at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="PTHR12147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M28" evidence="1">
        <location>
            <begin position="99"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="338" mass="37071" checksum="ADC3B4D9D2A3B212" modified="2016-02-17" version="1">MKWLRRLSLLLALVAAAAAALLFAVVQPGVSPRPSAPPAADAQRLREDVKRLSVDFYPRSYDVPGQLDRVSAWLHDEFQRAGARVSYQPVSVEGQAYRNVVARFGPDEGPLRVIGAHYDSFAETGIDSGDERGYSLYTHTPGADDNASGVAGLLELARMLGRAPPSRPIELVAYTLEEPPHFRSEHMGSAWHARALRASGREVEFMLSLEMIGRFSDRPGSQTYPVRGMHRLYSDRGDFVAVVGRMGDFGLSRKVKAAMAGATPLPVHSINAPPLLVQGVDFSDHRSYWGEGFPALMIGDTAFLRSRRYHQPDDTYETLDYARMAQVVQGAYAAATGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEN5</accession>
    <name>A0A0S2DEN5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1631</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1631"/>
    <dbReference type="EnsemblBacteria" id="ALN56988">
        <property type="protein sequence ID" value="ALN56988"/>
        <property type="gene ID" value="GLE_1631"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1631"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1611"/>
    <dbReference type="OMA" id="AHYDPMP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="195"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="503" mass="53439" checksum="38818811810ACA49" modified="2016-02-17" version="1">MNATDVTATDSSRPDSNQPGSNRPGSNRPNSKRPNSKRPRHSTPPRAQRLSAAFALLLCATQAVAAEPVAARPGANATEPRASGSCAIGSYRLADGRPLDIGPGVEGQLRWRSDDGRTGALALAAHGAWISTVGWTGRADGHRVRFDCAHGRLRFDDTPGQRVRTIQRDTRFRGSGVELAGRLTLPSGEGRVPLVVLVHGAEHDSALQRYSLQREFANAGIATFVYDKRGTGASGGRYTQDYLTLAVDAVHALDEARRLGGARIGRVGYQGGSQGGWVAPLAVRIAPVDFVVVGFGLAVSPLEEDREAIAFDLRRAGFGDDPAAMAGAMAIADATAALIDSGFAEGYERLAAVKAQYAQAPWYASVRGNFTWYLLGNDADTIRRDAPGLVRGVPAHYDPMPVLRGLDTPQLWALGGEDRDAPPGETLRRLAALQRAGKPIASAVFARADHGLYEFETAADGERVSTRQPDGYFRLMTDFILGKTLQPRYGEAAVCASAACAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEV1</accession>
    <name>A0A0S2DEV1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">3-oxoacyl-[acyl-carrier-protein] synthase 2</fullName>
            <ecNumber evidence="3 10">2.3.1.179</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">fabF</name>
        <name evidence="15" type="ORF">BV903_07290</name>
        <name evidence="16" type="ORF">FE772_08780</name>
        <name evidence="14" type="ORF">GLE_1694</name>
    </gene>
    <organism evidence="14 17">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">C3</strain>
        </source>
    </reference>
    <reference evidence="15 18" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 18">B25</strain>
        </source>
    </reference>
    <reference evidence="16 19" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 19">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(9Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxo-(11Z)-octadecenoyl-[ACP] + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:55040"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10800"/>
            <dbReference type="Rhea" id="RHEA-COMP:14074"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:83989"/>
            <dbReference type="ChEBI" id="CHEBI:138538"/>
            <dbReference type="EC" id="2.3.1.179"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a fatty acyl-[ACP] + H(+) + malonyl-[ACP] = a 3-oxoacyl-[ACP] + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:22836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10 12">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.179" evidence="3 10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000013">
        <property type="protein sequence ID" value="OPD64683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946983.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1694"/>
    <dbReference type="EnsemblBacteria" id="ALN57050">
        <property type="protein sequence ID" value="ALN57050"/>
        <property type="gene ID" value="GLE_1694"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64683">
        <property type="protein sequence ID" value="OPD64683"/>
        <property type="gene ID" value="BV903_07290"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1694"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1672"/>
    <dbReference type="OMA" id="QIGHCLG"/>
    <dbReference type="OrthoDB" id="606297at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017568">
        <property type="entry name" value="3-oxoacyl-ACP_synth-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000447">
        <property type="entry name" value="KAS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03150">
        <property type="entry name" value="fabF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 14" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 12 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="13">
        <location>
            <begin position="10"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000447-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN57050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OPD64683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QCW25748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="417" mass="43754" checksum="ABF65ED889A007A0" modified="2016-02-17" version="1">MSNRSFNRRVVVTGLGLVSPLGNDVASSWDGIVNGRCGIGPITHFDPAAFTTRIAGEVRDFDITRYGVSTKDAKKMDEFIHYGVAASLMALQDAGIVVDDSNAERIGALVGSGIGGLLGIEEQTIKYHEGGPRKISPFYVPSTIINMLPGQISLITGAKGPNFSAVSACATSNHSIGVAMRMIQYGDADVMVAGGAERGSSPTSVGGFCSMKAMSTRNDDPARASRPWDKDRDGFVLGDGAGILILEEYERAKARGARIYCELAGFGASSDAFHMTAPSENGEGPARCMVAAFKDAGINPEQVEYLNAHGTSTPLGDLAETLAMKRALGDHAYKMMVSSTKSMTGHLLGAAGGAEAIFSVLALHHGIIPPTINLDEPGEGCDLDYVPNVAREKKIDVAVSNGFGFGGTNGTLVFKRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEX0</accession>
    <name>A0A0S2DEX0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rhs family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1773</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1773"/>
    <dbReference type="EnsemblBacteria" id="ALN57127">
        <property type="protein sequence ID" value="ALN57127"/>
        <property type="gene ID" value="GLE_1773"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1773"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1748"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045351">
        <property type="entry name" value="DUF6531"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001826">
        <property type="entry name" value="RHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031325">
        <property type="entry name" value="RHS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006530">
        <property type="entry name" value="YD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20148">
        <property type="entry name" value="DUF6531"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05593">
        <property type="entry name" value="RHS_repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00394">
        <property type="entry name" value="RHSPROTEIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
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            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
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        <location>
            <begin position="35"/>
            <end position="1591"/>
        </location>
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    <feature type="domain" description="DUF6531" evidence="2">
        <location>
            <begin position="235"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
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    </evidence>
    <sequence length="1591" mass="172456" checksum="A9211AFE258CC8AB" modified="2016-02-17" version="1"> </sequence>
</entry>
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            <authorList>
                <person name="Feng T."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3.</text>
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        <source>
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        <source>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </evidence>
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            <dbReference type="Proteomes" id="UP000061569"/>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFF1</accession>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFG1</accession>
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            <authorList>
                <person name="Kobayashi D.Y."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="62" mass="6744" checksum="DC7B778C0C4132AE" modified="2016-02-17" version="1">MFGRPELFQHGGSSWCCVCPRAASVRSVIPAKAGSALFRRSRTSRASPMQDSEVSGFPLSRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFH9</accession>
    <name>A0A0S2DFH9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1930</name>
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    <organism evidence="3 4">
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1930"/>
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    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="chain" id="PRO_5006595093" evidence="2">
        <location>
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        </location>
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        <location>
            <begin position="440"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="468" mass="51250" checksum="DBA2E2EFF7F4658A" modified="2016-02-17" version="1">MLGAAAAACVAASAISQERSAAAVPMPASAAAAAAPRFPSYDPRYPPPPGTPPAQVFQLSQDFPKTYAADTFAWEKIDFKAFPNEYLRAVLNYCLEGNVDVDFRVQDNPVRKWYHAPWLHDDGSQFGGGREWRRGMTRERMSRPFELHSKQTGRGQNWAVGFYNDRGGVGLGKVWLTADGRPDPAKSTFPPNTVACKLLFTDAPVEQVPYLANGKVWTANIYPDTNYNKPRVDKEMRLLQLDVAVKDPRLARSSGWVFGTFVYDGGSPGKTVWDRMSPVGLIWGDDQSVRIDAQRNGVFVNTALTQSRINGFLVEQPGWDYGNRAYVRHHGLGGRVNGPIDSPISSCVSCHGRAGTFANAADPVNRGRPMAMAVFSANKPSDFPMDKFDEFFKPIADGAHLETQDGSQFMTTDYSLQVTGGIRNYYQNLRSQPPVVAEAAGNARGARAAAPVDLSDAPPLPRVDRDAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGA8</accession>
    <name>A0A0S2DGA8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_11585</name>
        <name evidence="2" type="ORF">GLE_2306</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947438.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57655">
        <property type="protein sequence ID" value="ALN57655"/>
        <property type="gene ID" value="GLE_2306"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2306"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2271"/>
    <dbReference type="OMA" id="HYRVHLQ"/>
    <dbReference type="OrthoDB" id="2056668at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045500">
        <property type="entry name" value="DUF6491"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20101">
        <property type="entry name" value="DUF6491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242167" evidence="1">
        <location>
            <begin position="23"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="116" mass="12532" checksum="2996C9F08087BB50" modified="2016-02-17" version="1">MKLLSAIAVATALAAACAPALAAEPLQDCTDLGAQHSVRRAGDGAVAIRDGEQYYRAQTRQGCSDLSYSGKLSISTDDQSARLCPQGSKLTTERDYCSITRVEKIDAQAYKRYTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGR3</accession>
    <name>A0A0S2DGR3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2333</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947460.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57682">
        <property type="protein sequence ID" value="ALN57682"/>
        <property type="gene ID" value="GLE_2333"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2333"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2297"/>
    <dbReference type="OMA" id="KIRQPFA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595147" evidence="2">
        <location>
            <begin position="30"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="223" mass="23635" checksum="0772D6884212A319" modified="2016-02-17" version="1">MSLPSIRHAALRSAPLLAALWFAASAAHAQSANETRLRDALRDTASRLRTAEAALAQQQAATAAAERERDELKGRAAKPAPAADGAQLAALQQRLGQASASAEQARGEALKWRSAQEQAAHSAQQKERERAELAKRLDAAQARAADCAAGSEALYQAGRELAQLYRDPAYAKGKRVTLLGFGQVERENRARELENKLEDERAKTAQCGAGDAAARTAGTASNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGV0</accession>
    <name>A0A0S2DGV0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase, group 1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2464</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2464"/>
    <dbReference type="EnsemblBacteria" id="ALN57813">
        <property type="protein sequence ID" value="ALN57813"/>
        <property type="gene ID" value="GLE_2464"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2464"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2426"/>
    <dbReference type="OMA" id="AWQLARI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="25"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="202"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="384" mass="41632" checksum="8CE43600EB182BBC" modified="2016-02-17" version="1">MSALAQTGSATVRSVLLYLPQLKLGGAEISILRLAQGLQARGVAVALAVHRADASAQALAGDIELLSLDAGRTLAVPGRLAQLLRQRRPDVLVSALTHSNIVAALAARGTGVRTVLTEHAPIASMRRLDRSRRYRATVALMPWAYRHADAVVAVSEGVREDIAAHLRQDQRRRLHVIANPVLPRDWRERADAPLAEDGYGADGAPTILSVGRLSEEKNFAGLIRAFARLRTPLRLHLAIVGEGPQRPALQALIDELGLGRVVRLLGQRDNPYPYMRRARVFALASQFEGFGNVLIEAMACGAPVVSTDCPVGPREVLAGGRYGLLVPPDDPGALAEAIERQVRHADPQVLAAAREHALQFTVERSAERYLQLFERLMDDGAARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH06</accession>
    <name>A0A0S2DH06_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_12695</name>
        <name evidence="2" type="ORF">GLE_2528</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947610.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2528"/>
    <dbReference type="EnsemblBacteria" id="ALN57877">
        <property type="protein sequence ID" value="ALN57877"/>
        <property type="gene ID" value="GLE_2528"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2528"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2490"/>
    <dbReference type="OMA" id="YLIDFPA"/>
    <dbReference type="OrthoDB" id="1552415at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010390">
        <property type="entry name" value="DUF990"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06182">
        <property type="entry name" value="ABC2_membrane_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="274" mass="29471" checksum="ED634795349ABA78" modified="2016-02-17" version="1">MSAEAPASARRRRPSASLHAVALGLQEAMQHKADFALGFVSAAFPLFVQYYLWSSLYARGYSIPGYAYADALLYSVLAAVVGRLVHTGFEYEVGNDIKHGGLARYLVQPVAYVRLRLAHFVGGKLPMYAIMGALLLAALAFGGAAAGERLGLLPAVLAAVALGVAINFLIFLCVSFTCFWFDEAAYLFEGIRIGIVVLSGGIVPLAVFGRAQDVLHWLPFRYIISAPIEIAMGRIETAALPQLLGVQALWVAVFGLIAWAMWRVGLRSFMATGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH07</accession>
    <name>A0A0S2DH07_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type VI secretion protein, VC_A0111 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2578</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2578"/>
    <dbReference type="EnsemblBacteria" id="ALN57927">
        <property type="protein sequence ID" value="ALN57927"/>
        <property type="gene ID" value="GLE_2578"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2578"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2537"/>
    <dbReference type="OMA" id="WADAQST"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010732">
        <property type="entry name" value="T6SS_TssG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35564">
        <property type="entry name" value="PTHR35564"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06996">
        <property type="entry name" value="T6SS_TssG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03347">
        <property type="entry name" value="VI_chp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="350" mass="39467" checksum="4AB83EFFC08C4094" modified="2016-02-17" version="1">MARKARKPTDPVTRGAASADAARLLRALRERPQDFELFEALRRIECAFPQHPRLGQAARPQDEPVRLGQRASLDFAPRSVDALDETGGGRAPRLRTFPLGLFGPQGALPLHLTEYAIERERMDQDPTLAAFADLFHHRMIALWYRSWADARPTVHADRPDQDRFGGHVDALVGVGQPALRERDALAPDVRRYFAGRFAAQARNAEGLQAAIRTLFDVPLTVQSFFADWLDLPPDGRLGMGRQAARLGQEATMGAKFRNAQHRFRLRIGPLDLPRYREFLPGGRALRELVALVRHYCGDEYLWDLQLVLDRSQVPPPRLGKSQRMGQSLWMGDYRKPEHADDLVLQPALNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHC3</accession>
    <name>A0A0S2DHC3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Efflux RND transporter periplasmic adaptor subunit</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_13040</name>
        <name evidence="3" type="ORF">GLE_2597</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947665.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2597"/>
    <dbReference type="EnsemblBacteria" id="ALN57945">
        <property type="protein sequence ID" value="ALN57945"/>
        <property type="gene ID" value="GLE_2597"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2597"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2557"/>
    <dbReference type="OMA" id="RASILIK"/>
    <dbReference type="OrthoDB" id="1432684at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="72"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="396" mass="42105" checksum="DE560C41EADCF25F" modified="2016-02-17" version="1">MPIAPPSSPKSRLFIAAAVCAALAAMLAWRFWPSAPAAAAAEQAAVPVRAAAAKRESFAVTLKALGTVTPLSYVTLRSRVEGELVEVAFQEGQQVRAGQLLARIDPSTYQVQLAKAEGQQQENLATLDNARRELARYRELKAGHYVSAQDVSNREAQVRQLEGRRRSDQAAVDEARVRLGHTRIVAPVSGRVGLRGIDRGNLVGAGNAAGEAIASIAQTSPISVMFTVAENELPALLEAVRRQPDLPVEAWDREERTRLASGRVASIDNRIDSATGTLRIRAVFDNADAALFPQQFVNVRLNTQRSDAVVIPDAAVQFGAKGNYVFVIGADSKVAIRPLKLGAAQDGRIAVHEGLKPDERVVLEGLDRLREGSAVEVIADAAAGGPAAAARAAGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHD5</accession>
    <name>A0A0S2DHD5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_11615</name>
        <name evidence="2" type="ORF">GLE_2314</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947443.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2314"/>
    <dbReference type="EnsemblBacteria" id="ALN57663">
        <property type="protein sequence ID" value="ALN57663"/>
        <property type="gene ID" value="GLE_2314"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2314"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2279"/>
    <dbReference type="OMA" id="MMAAIME"/>
    <dbReference type="OrthoDB" id="1389691at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="147" mass="16106" checksum="3235C324D3191A32" modified="2016-02-17" version="1">MLSFRDDALSDADFAVVHGVLSQTYWAAGIPAETLRRALDGSLCYRGYLDGELVAFARAVTDQATFAYLADVFVVPAHRGRGYGRAVVEALMADPRVQGLRRWLLVTSDMQPLYAKLGFTALPRPEQHMQKHDPDVYLRAGGAAPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHH4</accession>
    <name>A0A0S2DHH4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2771</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58119">
        <property type="protein sequence ID" value="ALN58119"/>
        <property type="gene ID" value="GLE_2771"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2771"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2728"/>
    <dbReference type="OMA" id="HEVARED"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="218" mass="23751" checksum="6F9592ECFDE97D1F" modified="2016-02-17" version="1">MDKPSAPGRRPAPLPPSRAAARRARAVAALLALFAATGCQTAMSSTAAPDPSAGAQAAAAQWPLRFQRHRFGGFCFDTWGCSIVYNGFPHGQEDRERQSASAASFGAAYPQRMKAAHLDIANFPGPAEVTWRAKDKSEHRASIDIAAIFADGLVRHEVAREDMAEGVSLNDPEIILEVNDRTINVYMRSMIALKRPRDPANPNSNFRADLVRVFSQTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHI1</accession>
    <name>A0A0S2DHI1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2483</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947572.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2483"/>
    <dbReference type="EnsemblBacteria" id="ALN57832">
        <property type="protein sequence ID" value="ALN57832"/>
        <property type="gene ID" value="GLE_2483"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2483"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2445"/>
    <dbReference type="OMA" id="ANIFWRD"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13443">
        <property type="entry name" value="HTH_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="11"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="185"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="254" mass="28816" checksum="508DFF0482B0F75A" modified="2016-02-17" version="1">MAERERLLAALKRILKERGWRYADLAAALGLSEPTIKRMLSNGRIGLDRLEQICEALDIDFFELARSARGNRDARRHLSLAQETALAAEPRLMTVFHLLCQGWQTAAIGADYGLRKPELVKLLARLDALRLIELLPGDRTRLRVARDFSWRDDGPVRARYFQLASREFLNHGFDGGDAFFALEIRELSEASAATLRRKLDKLVAEFKEAADLDIGLPPERRRSVGMLAASRPWVFSLVESLREAEPAADKPRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHQ7</accession>
    <name>A0A0S2DHQ7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2710"/>
    <dbReference type="EnsemblBacteria" id="ALN58058">
        <property type="protein sequence ID" value="ALN58058"/>
        <property type="gene ID" value="GLE_2710"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2710"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2669"/>
    <dbReference type="OMA" id="LPIGWIW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="234"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="311"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="343" mass="36631" checksum="08242DA6F3B3205E" modified="2016-02-17" version="1">MNAATDDYSASTAAVPRAAAAIAPSRVFLMLLKREFWEHRGGFLWGPLIAGAIAIVFTVLGVIGGSVLFRKVANEHGEGINFEMSGGEIGRAGSIGDAALAGGLGMVCLVFVFVVFFYALGSIYDERKDRSILFWKSLPVSDTQAVLSKLVWALLLAPLLAAAIGLAVGLVMWVLAWLAAVLNGFPGAGAIFTQAHPFRLLAELAVSVPVYALWALPTVGWLMLCSAWARSVPFVWAVVIPLLACVFVSFLDIMPGIEIPHGAIWYTVALRGLLSVVPGTWFLHEQMNGDAQQAALKGTEALSQLDSVNSLHVLATADLWIGAALGAAMIYAAIRLRRWRDDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHU0</accession>
    <name>A0A0S2DHU0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator, lacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_2785</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2785"/>
    <dbReference type="EnsemblBacteria" id="ALN58133">
        <property type="protein sequence ID" value="ALN58133"/>
        <property type="gene ID" value="GLE_2785"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2785"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2741"/>
    <dbReference type="OMA" id="YNRYDAY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00036">
        <property type="entry name" value="HTHLACI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="5">
        <location>
            <begin position="4"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="315"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="335"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="373" mass="39596" checksum="CCF922638B8F5ECC" modified="2016-02-17" version="1">MVSVTIKDVARAAQVSVATVSRTLNGHGNVAEDVRRRVLAVANDLRYTPHAAARSLSSRRTQTLGVVLPDLHGEFFSELVRGVDQVAREHRLHLLVSSYHGQPEEQVSALRAMRGRVDGLLVMSPYAAAQVSIAEELSATLPTVLINAQDASADTPSLNVDNYGGAQAMVEYLVGAGHRRIAFIAGPDDNFDANERLRGYREALARLLPGAREWVLPGRFDEASGHAAGSALLAADERPDAVFAANDMMALGCLFGLVQGGLRVPGDIAVTGFDDIPLARYVHPALTTMRVNIAELGARAARMLLARLNPEPAAADAAAAHANPAQAAGTDEDPTPADRAGDNDSNPEKPRQSEPLRPELIVRESGLRRGGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI05</accession>
    <name>A0A0S2DI05_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Type VI secretion protein IcmF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">icmF</name>
        <name evidence="6" type="ORF">GLE_2586</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2586"/>
    <dbReference type="EnsemblBacteria" id="ALN57935">
        <property type="protein sequence ID" value="ALN57935"/>
        <property type="gene ID" value="GLE_2586"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2586"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2545"/>
    <dbReference type="OMA" id="GRQPING"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009612">
        <property type="entry name" value="IcmF-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025743">
        <property type="entry name" value="IcmF-related_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010623">
        <property type="entry name" value="IcmF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017731">
        <property type="entry name" value="TssM1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06761">
        <property type="entry name" value="IcmF-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14331">
        <property type="entry name" value="IcmF-related_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06744">
        <property type="entry name" value="IcmF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03348">
        <property type="entry name" value="VI_IcmF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="451"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="IcmF-related_N" evidence="5">
        <location>
            <begin position="201"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="IcmF-related" evidence="4">
        <location>
            <begin position="513"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="domain" description="IcmF_C" evidence="3">
        <location>
            <begin position="1045"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="811"/>
            <end position="851"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1163" mass="126796" checksum="89AC320E444D70E3" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI44</accession>
    <name>A0A0S2DI44_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Beta-phosphoglucomutase</fullName>
            <ecNumber evidence="8">5.4.2.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pgmB</name>
        <name evidence="8" type="ORF">GLE_2764</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="3">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.6" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947796.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2764"/>
    <dbReference type="EnsemblBacteria" id="ALN58112">
        <property type="protein sequence ID" value="ALN58112"/>
        <property type="gene ID" value="GLE_2764"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2764"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2721"/>
    <dbReference type="OMA" id="EAYCIPF"/>
    <dbReference type="OrthoDB" id="179460at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008801">
        <property type="term" value="F:beta-phosphoglucomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02598">
        <property type="entry name" value="HAD_BPGM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010976">
        <property type="entry name" value="B-phosphoglucomutase_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010972">
        <property type="entry name" value="Beta-phosphoglucomutase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005194">
        <property type="entry name" value="Glyco_hydro_65_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005195">
        <property type="entry name" value="Glyco_hydro_65_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005196">
        <property type="entry name" value="Glyco_hydro_65_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037018">
        <property type="entry name" value="Glyco_hydro_65_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03633">
        <property type="entry name" value="Glyco_hydro_65C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03632">
        <property type="entry name" value="Glyco_hydro_65m"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03636">
        <property type="entry name" value="Glyco_hydro_65N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01990">
        <property type="entry name" value="bPGM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02009">
        <property type="entry name" value="PGMB-YQAB-SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_65N" evidence="7">
        <location>
            <begin position="25"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_65m" evidence="5">
        <location>
            <begin position="334"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_65C" evidence="6">
        <location>
            <begin position="718"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="799"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="834"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="904"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="799"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="801"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="799"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="801"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="815"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="842"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="866"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="935"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="959"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="960"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups" evidence="4">
        <location>
            <position position="904"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups" evidence="4">
        <location>
            <position position="935"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR610972-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR610972-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR610972-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR610972-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1005" mass="109290" checksum="BCBA4684B7772DF3" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI71</accession>
    <name>A0A0S2DI71_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">Cell division protein ZipA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 13" type="primary">zipA</name>
        <name evidence="14" type="ORF">BV903_21325</name>
        <name evidence="15" type="ORF">FE772_13775</name>
        <name evidence="13" type="ORF">GLE_2757</name>
    </gene>
    <organism evidence="13 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">C3</strain>
        </source>
    </reference>
    <reference evidence="14 17" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">B25</strain>
        </source>
    </reference>
    <reference evidence="15 18" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 18">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Interacts with FtsZ via their C-terminal domains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <text evidence="8">Localizes to the Z ring in an FtsZ-dependent manner.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the ZipA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000069">
        <property type="protein sequence ID" value="OPD61908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947790.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000069.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2757"/>
    <dbReference type="EnsemblBacteria" id="ALN58105">
        <property type="protein sequence ID" value="ALN58105"/>
        <property type="gene ID" value="GLE_2757"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61908">
        <property type="protein sequence ID" value="OPD61908"/>
        <property type="gene ID" value="BV903_21325"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2757"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2714"/>
    <dbReference type="OMA" id="NERTEPN"/>
    <dbReference type="OrthoDB" id="1632200at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090529">
        <property type="term" value="P:cell septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00509">
        <property type="entry name" value="ZipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011919">
        <property type="entry name" value="Cell_div_ZipA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007449">
        <property type="entry name" value="ZipA_FtsZ-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036765">
        <property type="entry name" value="ZipA_FtsZ-bd_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38685">
        <property type="entry name" value="PTHR38685"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04354">
        <property type="entry name" value="ZipA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00771">
        <property type="entry name" value="ZipA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64383">
        <property type="entry name" value="SSF64383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02205">
        <property type="entry name" value="septum_zipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 8 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 8 10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 8 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="ZipA_C" evidence="12">
        <location>
            <begin position="108"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="34"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN58105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OPD61908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW26573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="256" mass="27917" checksum="5008D5EBA1CE9AD2" modified="2016-02-17" version="1">MSDVTLMRIGILIAGLILIVAIVFFGRPRKSGQGKRIAREDEARGGERKPAARQEPSLGEQIENELGAGGQPVGEATSQAELELFDRTLEGGANAAASELGRRVSDEFDKIVTLYLAARAGQKLHGPDIVVAAEKAGLVYGHMGVYHRLVEGHPERGPVFSVANIMKPGSFDMAQIQALETPAIAFFLTLPAPVPALDAWETMLPTAQRMAELLDAVVLDEQRNALGRQRIAHLRDELRAYDRQREAPPLSKPTRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI80</accession>
    <name>A0A0S2DI80_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Poly(3-hydroxyalkanoate) polymerase subunit PhaC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">PHB synthase subunit PhaC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">phaC</name>
        <name evidence="7" type="ORF">FE772_14270</name>
        <name evidence="6" type="ORF">GLE_2858</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Biopolymer metabolism; poly-(R)-3-hydroxybutanoate biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947866.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2858"/>
    <dbReference type="EnsemblBacteria" id="ALN58206">
        <property type="protein sequence ID" value="ALN58206"/>
        <property type="gene ID" value="GLE_2858"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2858"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2820"/>
    <dbReference type="OMA" id="YLIDWGY"/>
    <dbReference type="OrthoDB" id="891360at2"/>
    <dbReference type="UniPathway" id="UPA00917"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042619">
        <property type="term" value="P:poly-hydroxybutyrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010125">
        <property type="entry name" value="PHA_synth_III_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01836">
        <property type="entry name" value="PHA_synth_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0583">PHB biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="5">
        <location>
            <begin position="68"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW26649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="356" mass="40294" checksum="E5D7101704C5FDF8" modified="2016-02-17" version="1">MTAPINFTAESLAQEALNAQRKLSAGLETLHEVDDIDYGATAREEVWRDGKVALYRFRGEQAPTAKAPLLIAYALVNRPYMVDLQADKSIVRGLLERGQDVYILDWGYPDRSDRYLELEDYIQRFLGGAVDHLRREYRQDAINLLGICQGGAFSLCYSALNPAKVRNLITMVTPVDFHTRDNMLSNWTRGLDVDQFVDTLGNVPADVMNWCYLTLKPWRLFVQKYVGLIDILDDKRALEDFLRMEKWIFDSPDQAGEAFRQFIKQFYQGNGFVNGGIDIGGRAVDLGYVDMPVLNIYAEQDHLVPPAASKALKDLVGSEDYSELSFKGGHIGIYVSGRAQREVPGAIHDWLTQRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI98</accession>
    <name>A0A0S2DI98_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase</fullName>
            <ecNumber evidence="1">1.3.1.28</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">entA</name>
        <name evidence="1" type="ORF">GLE_2619</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.3.1.28" evidence="1"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2619"/>
    <dbReference type="EnsemblBacteria" id="ALN57967">
        <property type="protein sequence ID" value="ALN57967"/>
        <property type="gene ID" value="GLE_2619"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2619"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2578"/>
    <dbReference type="OMA" id="ICPGIIE"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008667">
        <property type="term" value="F:2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019290">
        <property type="term" value="P:siderophore biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003560">
        <property type="entry name" value="DHB_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01397">
        <property type="entry name" value="DHBDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04316">
        <property type="entry name" value="dhbA_paeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="249" mass="25764" checksum="F6423E7273417821" modified="2016-02-17" version="1">MVGAAQGIGAATAARLAGEGARLALMDRDQARLQATAQALRGQAAQVSTQACDVADIGAVEAAVARIENELGPIAHLAHVAGILRVGAAVELDPDDWDACMAVNARGVFATTRAVASRMRERRVGSIVAVGSNAAAAPRTGMSAYAASKAAATQYLRCLALELAPCGVRCNIVSPGSTDTAMQRAFAADEAARQRILRGDGERFRIGIPLGRIAEPDDVAEAVCFLLSDRARHITLHDLRVDGGATLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIB1</accession>
    <name>A0A0S2DIB1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA-binding transcriptional accessory protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcription-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_15360</name>
        <name evidence="3" type="ORF">GLE_3076</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948025.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3076"/>
    <dbReference type="EnsemblBacteria" id="ALN58423">
        <property type="protein sequence ID" value="ALN58423"/>
        <property type="gene ID" value="GLE_3076"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3076"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3036"/>
    <dbReference type="OMA" id="RWAWRTR"/>
    <dbReference type="OrthoDB" id="120764at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05685">
        <property type="entry name" value="S1_Tex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3500.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041692">
        <property type="entry name" value="HHH_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044146">
        <property type="entry name" value="S1_Tex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023323">
        <property type="entry name" value="Tex-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023319">
        <property type="entry name" value="Tex-like_HTH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018974">
        <property type="entry name" value="Tex-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032639">
        <property type="entry name" value="Tex_YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006641">
        <property type="entry name" value="YqgF/RNaseH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17674">
        <property type="entry name" value="HHH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09371">
        <property type="entry name" value="Tex_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16921">
        <property type="entry name" value="Tex_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00732">
        <property type="entry name" value="YqgFc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="660"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="730"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="745"/>
            <end position="759"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="797" mass="86829" checksum="10013D7A9C4CDFF7" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIC9</accession>
    <name>A0A0S2DIC9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ThiF family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tcdA</name>
        <name evidence="3" type="ORF">FE772_15290</name>
        <name evidence="2" type="ORF">GLE_3059</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948012.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3059"/>
    <dbReference type="EnsemblBacteria" id="ALN58406">
        <property type="protein sequence ID" value="ALN58406"/>
        <property type="gene ID" value="GLE_3059"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3059"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3019"/>
    <dbReference type="OMA" id="DMDDICV"/>
    <dbReference type="OrthoDB" id="1543144at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43267">
        <property type="entry name" value="PTHR43267"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="SSF69572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ThiF" evidence="1">
        <location>
            <begin position="24"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="275" mass="29591" checksum="4D8B2F8539BE94E4" modified="2016-02-17" version="1">MNAIASESAADTLWQERFAGIDRLYGQGAVARFRQCRVAVVGMGGVGSWAVEALARTGIGHLTLIDADDLCVSNTNRQLPALAGQYGRAKVEAMAERCRAINPGIEVDAVQSFLTPSNLSELLDRGFDLVLDACDSFRSKVELIAWCRRRKLPVIAVGSAGGRTDPTLVRVRDLSRTEHDAMLALIRKKLRSEFNFPKNASRYFGVSAIYSLENVKYPQPDGTVCGLRPKLDGDAALKLDCGAGLGAATHITGVFAFAAVGRALEILLKPKAQAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DII8</accession>
    <name>A0A0S2DII8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Iron-sulfur cluster carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_3157</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3157"/>
    <dbReference type="EnsemblBacteria" id="ALN58503">
        <property type="protein sequence ID" value="ALN58503"/>
        <property type="gene ID" value="GLE_3157"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3157"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3114"/>
    <dbReference type="OMA" id="SIPLMMN"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000808">
        <property type="entry name" value="Mrp_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044304">
        <property type="entry name" value="NUBPL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961">
        <property type="entry name" value="PTHR42961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01215">
        <property type="entry name" value="MRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="106"/>
            <end position="113"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="358" mass="36707" checksum="763C6F2ED3F187DE" modified="2016-02-17" version="1">MSEHLQSPLAATIAALPLPDTGLSLADSGARVRAGAAEGRVAVSIQAGFALDGLRPGLEASIAAALAPQGLALASLELIARIVSHAVQPKLSPLPNVRNLIAVGSGKGGVGKSTTAVNLALALALDGARVGVLDADIYGPSVPTMLGAHGKPDSPDGKHIQPLRAHGIEAMSIGPLVEQDTPMIWRGPMATSALTTLLNDTQWSELDYLIVDLPPGTGDIQLTLAQKIPVAGAVIVTTPQDVATLDARKALRMFEKVEVPVLGLVENMAVHVCSNCGHAEHLFGEGGGARMAAQYGVPLLGSLPLEIAIREQGDAGVPVVAAQPDSAAARAYRGTARRLAVELARRPRVAPSISASLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIK9</accession>
    <name>A0A0S2DIK9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Patatin-like phospholipase family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Phospholipase, patatin family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_14960</name>
        <name evidence="5" type="ORF">GLE_2991</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2991"/>
    <dbReference type="EnsemblBacteria" id="ALN58339">
        <property type="protein sequence ID" value="ALN58339"/>
        <property type="gene ID" value="GLE_2991"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2991"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2952"/>
    <dbReference type="OMA" id="SCAIPGW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="4">
        <location>
            <begin position="53"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="89"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="259"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW26753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="440" mass="48160" checksum="59A4103C63E49EEE" modified="2016-02-17" version="1">MLSLHSARHRASREPAAKGSKNTGPRKNAAQRNGAAADSARRDPAAAPRIGLAIAGGGPIGGMYELGALRALDEAIDGLDLTRLDCYVGVSSGAFLAAGLANRMDTAEMCRIFITGDSGDVRFRPETFMRPAFVEYLKRAASFPRLATEWWRELLFSPLEARWSDLITRFGGLIPNGLFDNSEVERFLREVFTRRGRSNDFRELDAKLYVVAVDIDSGDAVRFGDAGWDDVPISKAVQASAALPGLYPPVNIEGRHFVDGALRRTMHASVVLEQGIDLLIGLNPLVPFNHGHGAAVAEDNSLAAGGLPAVLSQTFRTLLQSRMQVGLARYAQQYPDIDQLVFEPNAEDRELFFTNAFSFSARRRICEIAYRNTLADLRARAAQLAPILAAHGLRLRDEVLADPERSILDGLAPPARDSETTARLRRALDDVDRLVARRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIM3</accession>
    <name>A0A0S2DIM3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3007</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3007"/>
    <dbReference type="EnsemblBacteria" id="ALN58355">
        <property type="protein sequence ID" value="ALN58355"/>
        <property type="gene ID" value="GLE_3007"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3007"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2968"/>
    <dbReference type="OMA" id="WIAMMAV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007894">
        <property type="entry name" value="MASE2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05230">
        <property type="entry name" value="MASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="223"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="355" mass="38610" checksum="4E7ED991C7E27F62" modified="2016-02-17" version="1">MTATDPSAYEAGRASEHLRFVGRIYRMRSLGLGVGFFAVAGVLYEQGAAWWTWAALFGNGFVWPSAAYLIASRSRDPEYAEYRNLLLDSAVGGVWIAVMQFNVVPSALLAVMLSADKIGVGGWRFLLRTAAAQALACALAWAALGFGFAPHSSMTVILACLPFMFVYPMAISSAAYGLARKVVRQNRQLAHLSRTDPLTGLQNRLHWDDSATATMTHCARSNKRAALVVIDVDRFKEINDYHGHQVGDAVLRRIADVLHRAARMTDTASRIGGDEFALIVMDIDGAGARAIAERLRCAVEDARFDEAPELRCTVSIGVAATGARTLTATMWMRHADAALYRAKQNGRNAVVEAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIQ8</accession>
    <name>A0A0S2DIQ8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter, permease protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Carbohydrate ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FE772_13880</name>
        <name evidence="6" type="ORF">GLE_2779</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2779"/>
    <dbReference type="EnsemblBacteria" id="ALN58127">
        <property type="protein sequence ID" value="ALN58127"/>
        <property type="gene ID" value="GLE_2779"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2779"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2736"/>
    <dbReference type="OMA" id="NGMWFAV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="65"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="179"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="69"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW28752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="273" mass="29765" checksum="1AB3A119247BFE28" modified="2016-02-17" version="1">MPAWLARAIVNGLLIGLAALSLAPLLWMLAVSLMQPGEAAAFPPPLWPASPTLHNYSELFSRMGMGRYLLNSFLVSTLVTVIAVLLNTLAGYAFAKLDFAGREGVFRLLLAALVIPAQVSMMPLFLMLKQMGLINTYAGAVVPGMAGIFGIFLVRQYARSIPDELLEAPRIDGAGELRIFFQIVLPALRPILVTLAIFSFLGAWNDFMWPLIVLSDEHLQTLPVALASLSREHVQDNEMMMAGSVVTVVPVLLLFLVLQRYYLQGLLVGSVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIR9</accession>
    <name>A0A0S2DIR9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3067"/>
    <dbReference type="EnsemblBacteria" id="ALN58414">
        <property type="protein sequence ID" value="ALN58414"/>
        <property type="gene ID" value="GLE_3067"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3067"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3027"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="1">
        <location>
            <begin position="112"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="194" mass="20928" checksum="51DB5C93F4A92F26" modified="2016-02-17" version="1">MPQPLTLLYWARRREELCFVEELRALAAAHANFQVRFLLTRQEPQAADEDAGRIDADLLARHARDLRERAVFACGPGGFVESARALADGAARSFASEAFTPPPRETREDGHAQVVLARSGRTFELPRGESLLTALEAQGLKLPSGCRMGLCNTCACGKSSGATRHLHTGELHAEPASALRLCVSAPAGDLVLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIW1</accession>
    <name>A0A0S2DIW1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CalU3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2868</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2868"/>
    <dbReference type="EnsemblBacteria" id="ALN58216">
        <property type="protein sequence ID" value="ALN58216"/>
        <property type="gene ID" value="GLE_2868"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2868"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2830"/>
    <dbReference type="OMA" id="GLHIERW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="402" mass="43379" checksum="0E19FC5BC161492B" modified="2016-02-17" version="1">MAPPGWLLIGPRDSRRLRGLQQALRERGLAAAEELHYEDLLDGGLGDGLDGGALAAPQRAAERIAARPGALVKIESPGEAPALHAALIERGWRALGAPGAPPRPLQHGELAYQHYWYAGFRELLDALPARAGYLNPPDDIAGMSDKLACQLRLRAQGIAIPPLLGELHSYEHLRALLREHGAGQVFVKARYGSSGAGVLAYRADRGGREAAYGSAELVEDGGVARVFNSLRPRRYDDSAQIARLVDAIAAQGAYVERWIPKPRAPDGEGGHYDIRAVALDGFLRHRVARVGRGPLTNLHLGNRRGALAQWLDDSAMHALEIATQQAAMAFPRSRMIGFDLILRDGRSWVLEANAFGDLLLDLPWQGLSTYQDQALLRPVPASNAPQAPHAPQAPHAPEPAHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIY7</accession>
    <name>A0A0S2DIY7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">von Willebrand factor, type A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3017</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947984.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3017"/>
    <dbReference type="EnsemblBacteria" id="ALN58365">
        <property type="protein sequence ID" value="ALN58365"/>
        <property type="gene ID" value="GLE_3017"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3017"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2978"/>
    <dbReference type="OMA" id="PGQNYIP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595097" evidence="1">
        <location>
            <begin position="28"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="344"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="540" mass="57927" checksum="0BB3740F959FE439" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ43</accession>
    <name>A0A0S2DJ43_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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    <dbReference type="KEGG" id="lez:GLE_3210"/>
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    <dbReference type="Proteomes" id="UP000061569">
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        <location>
            <begin position="10"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="47" mass="5294" checksum="5DEB6A1CCF8A5073" modified="2016-02-17" version="1">MDFDVWRYRRALPRAPPRGPRRGASSTYTRSAGEGGRATREAGWAEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJA2</accession>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <begin position="8"/>
            <end position="63"/>
        </location>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="260" mass="27304" checksum="1BA06D8D10B39962" modified="2016-02-17" version="1">MSVEELLPQQRHRLILERLLAQGRVIAVDLARELEVSHDTIRRDLREMAAAGQCRRVYGGALPLAPDRGTLVQRQAQAPGRKAALARAAIGLIERGQVLFLDAGSTNIAIAQALPADYGLTVATNAPAIAALLAPREDLQLIAIGGRIEPRIGAALGAGALREVEAIRSDWYFLGVCGADHEAGISARDYEDAQFKQAAAQAARAVAVLVTDDKFGTAAPYTVLAADAVAALVIEHDGDAAQARAFAAKGARVVRAGPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJJ9</accession>
    <name>A0A0S2DJJ9_LYSEN</name>
    <protein>
        <submittedName>
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        </submittedName>
        <submittedName>
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        </submittedName>
        <submittedName>
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        <name evidence="6" type="ORF">D9T17_11535</name>
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        <name evidence="3" type="ORF">GLE_3356</name>
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    <organism evidence="3 7">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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    <reference evidence="3 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">C3</strain>
        </source>
    </reference>
    <reference evidence="4 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">OH11</strain>
        </source>
    </reference>
    <reference evidence="5 10" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 10">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the ArsC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000114">
        <property type="protein sequence ID" value="OPD61108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000025">
        <property type="protein sequence ID" value="ROU06917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_RCTY01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3356"/>
    <dbReference type="EnsemblBacteria" id="ALN58702">
        <property type="protein sequence ID" value="ALN58702"/>
        <property type="gene ID" value="GLE_3356"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD61108"/>
        <property type="gene ID" value="BV903_25355"/>
    </dbReference>
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    <dbReference type="PATRIC" id="fig|69.6.peg.3306"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="entry name" value="Arsenate_reductase-like"/>
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        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <source>
            <dbReference type="ARBA" id="ARBA00007198"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW27014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROU06917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJL5</accession>
    <name>A0A0S2DJL5_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
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    </gene>
    <organism evidence="2 3">
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58718.1"/>
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    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="77" mass="8505" checksum="EEDC8C8FB4FE5DCA" modified="2016-02-17" version="1">MLSRRSPRTLLQRSRRAALNLDRLRRITTPAAGSGAAAGSGSARRRARPHDFSHVDDNCSQRHIDYICSYEAIPDGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJM7</accession>
    <name>A0A0S2DJM7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutamine amidotransferase</fullName>
            <ecNumber evidence="4">6.3.5.2</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Glutamine amidotransferase class-I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_24185</name>
        <name evidence="4" type="ORF">FE772_15580</name>
        <name evidence="2" type="ORF">GLE_3132</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.3.5.2" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000091">
        <property type="protein sequence ID" value="OPD61343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948066.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000091.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3132"/>
    <dbReference type="EnsemblBacteria" id="ALN58479">
        <property type="protein sequence ID" value="ALN58479"/>
        <property type="gene ID" value="GLE_3132"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61343">
        <property type="protein sequence ID" value="OPD61343"/>
        <property type="gene ID" value="BV903_24185"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3132"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3090"/>
    <dbReference type="OMA" id="SEGCKNQ"/>
    <dbReference type="OrthoDB" id="1242215at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003922">
        <property type="term" value="F:GMP synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01741">
        <property type="entry name" value="GATase1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044992">
        <property type="entry name" value="ChyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695">
        <property type="entry name" value="PTHR42695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="1">
        <location>
            <begin position="23"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="251" mass="28310" checksum="98A83A8DC5BE36BC" modified="2016-02-17" version="1">MSRILVFQHVAAEPLGTLDPLIRRRGHRIRFVNFDRDPGAAPNLERYRGLIVLGGPMNVEDRAARPHLTTELRAIESMLEQGKPVLGICLGAQLLAHVLGAPVRKHHVPEIGWYPLHSTDAGRTDPVLAPLAGSAPVFQWHRYSFEIPHGAHHLARTQTCEQQAFRWGDNAYGFQFHLEMDVPLIERWLANPAYRAELAELGHDTSEAAIRALTAQHIAGMQQRADAVFNNFLDLIGRPQRRYTLPSREWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJY8</accession>
    <name>A0A0S2DJY8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="13 14 15">UvrABC system protein B</fullName>
            <shortName evidence="14">Protein UvrB</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Excinuclease ABC subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14 19" type="primary">uvrB</name>
        <name evidence="20" type="ORF">FE772_17605</name>
        <name evidence="19" type="ORF">GLE_3574</name>
    </gene>
    <organism evidence="19 21">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="19 21" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 21">C3</strain>
        </source>
    </reference>
    <reference evidence="20 22" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 22">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 14">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12 14 15">Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="14">The beta-hairpin motif is involved in DNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14 15">Belongs to the UvrB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948390.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3574"/>
    <dbReference type="EnsemblBacteria" id="ALN58918">
        <property type="protein sequence ID" value="ALN58918"/>
        <property type="gene ID" value="GLE_3574"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3574"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3518"/>
    <dbReference type="OMA" id="TEYHQMI"/>
    <dbReference type="OrthoDB" id="95696at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00204">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004807">
        <property type="entry name" value="UvrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024759">
        <property type="entry name" value="UvrB_YAD/RRR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24029">
        <property type="entry name" value="PTHR24029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12344">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00631">
        <property type="entry name" value="uvrb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 14 15" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 14 15" id="KW-0228">DNA excision</keyword>
    <keyword evidence="9 14 15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 14 15" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="4 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 14 15" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="17">
        <location>
            <begin position="31"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="18">
        <location>
            <begin position="436"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="16">
        <location>
            <begin position="637"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Beta-hairpin" evidence="14">
        <location>
            <begin position="97"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00026033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ALN58918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="QCW27178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="676" mass="76499" checksum="37BC50113A307657" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK20</accession>
    <name>A0A0S2DK20_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">rplU</name>
        <name evidence="7" type="ORF">BV903_20960</name>
        <name evidence="8" type="ORF">FE772_16300</name>
        <name evidence="6" type="ORF">GLE_3293</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">C3</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">This protein binds to 23S rRNA in the presence of protein L20.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Contacts protein L20.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL21 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000066">
        <property type="protein sequence ID" value="OPD61952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948185.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000066.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3293"/>
    <dbReference type="EnsemblBacteria" id="ALN58639">
        <property type="protein sequence ID" value="ALN58639"/>
        <property type="gene ID" value="GLE_3293"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61952">
        <property type="protein sequence ID" value="OPD61952"/>
        <property type="gene ID" value="BV903_20960"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3293"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3244"/>
    <dbReference type="OMA" id="HRQEITR"/>
    <dbReference type="OrthoDB" id="1949059at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01363">
        <property type="entry name" value="Ribosomal_L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036164">
        <property type="entry name" value="L21-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028909">
        <property type="entry name" value="L21p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001787">
        <property type="entry name" value="Ribosomal_L21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018258">
        <property type="entry name" value="Ribosomal_L21_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349">
        <property type="entry name" value="PTHR21349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00829">
        <property type="entry name" value="Ribosomal_L21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141091">
        <property type="entry name" value="SSF141091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00061">
        <property type="entry name" value="L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01169">
        <property type="entry name" value="RIBOSOMAL_L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD61952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW26964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="106" mass="11702" checksum="D7FAC8B2AF7B02E7" modified="2016-02-17" version="1">MYAVLVTGGKQYRVMQGETLRVELLDVEAGSEIKFDTVLMLGDGEGIKIGDALKGASVTATVVGHGRADKVRIVKFRRRKHHRKQMGHRQHYTEIQITGIAGGDNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK26</accession>
    <name>A0A0S2DK26_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FE772_17965</name>
        <name evidence="9" type="ORF">GLE_3653</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3653"/>
    <dbReference type="EnsemblBacteria" id="ALN58997">
        <property type="protein sequence ID" value="ALN58997"/>
        <property type="gene ID" value="GLE_3653"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3653"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3597"/>
    <dbReference type="OMA" id="PAMQGFT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242230" evidence="6">
        <location>
            <begin position="43"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="75"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="7">
        <location>
            <begin position="403"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN58997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="1005" mass="109853" checksum="59F8962C45A4A719" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK78</accession>
    <name>A0A0S2DK78_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3472</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3472"/>
    <dbReference type="EnsemblBacteria" id="ALN58817">
        <property type="protein sequence ID" value="ALN58817"/>
        <property type="gene ID" value="GLE_3472"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3472"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3419"/>
    <dbReference type="OMA" id="FAFATEN"/>
    <dbReference type="OrthoDB" id="1268974at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="231"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="330" mass="35846" checksum="3363FAB351EA69B2" modified="2016-02-17" version="1">MFTSAKVRCAFNMSDALSISPRAGEAERTGLDGAAALGEAAARGWARQRRIERRHELELGPGLQFAFATENIAEPTQWSLEHARHTLIVHLDGPMRRLETRIDGAGRLRAAPAAGDWWLIPAGRRYLGRALGGEIAYAELNIDPVGFAALAPGLGENAGLAARMKHRDPFVHGIAARLAQLSEAGDDLAAMLRESLGQALCLHLLREHGAGAAARAAPAPAPVRLAEPARRRIEDHIQAHLDRRITLDELAGLGGLSTHQLLIAFRHAFGLTPIQYVLAQRLRRVCLRLRGSADDIATIAVENGFSSHSHLSAVFKKRYGLTPNEFRRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK94</accession>
    <name>A0A0S2DK94_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_25360</name>
        <name evidence="4" type="ORF">FE772_16575</name>
        <name evidence="2" type="ORF">GLE_3357</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000114">
        <property type="protein sequence ID" value="OPD61109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948235.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000114.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58703">
        <property type="protein sequence ID" value="ALN58703"/>
        <property type="gene ID" value="GLE_3357"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61109">
        <property type="protein sequence ID" value="OPD61109"/>
        <property type="gene ID" value="BV903_25360"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3357"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3307"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="143" mass="15881" checksum="A88E871400128177" modified="2016-02-17" version="1">MTRWVKQPFPGMALAVLGAMLVGGVFSRPWHPLSLLMAAGVVVLAAAIQRTMARHLADDVVDGGDHLLVRSGGIEEKVMLRDVASIRRGFGHNPERLILTLRLPGRLGDTIAFIPKGIRWFPYVEHPLAYELMTRARLLRLQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKN3</accession>
    <name>A0A0S2DKN3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NAD(P)H:quinone oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">NAD(P)H:quinone oxidoreductase, type IV</fullName>
            <ecNumber evidence="7 8">1.6.5.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">wrbA</name>
        <name evidence="8" type="ORF">FE772_18865</name>
        <name evidence="7" type="ORF">GLE_3831</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WrbA family.</text>
    </comment>
    <dbReference type="EC" id="1.6.5.2" evidence="7 8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948586.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3831"/>
    <dbReference type="EnsemblBacteria" id="ALN59174">
        <property type="protein sequence ID" value="ALN59174"/>
        <property type="gene ID" value="GLE_3831"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3831"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3773"/>
    <dbReference type="OMA" id="SRFGMMA"/>
    <dbReference type="OrthoDB" id="796211at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003955">
        <property type="term" value="F:NAD(P)H dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010089">
        <property type="entry name" value="Flavoprotein_WrbA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01755">
        <property type="entry name" value="flav_wrbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="6">
        <location>
            <begin position="4"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW27395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="197" mass="20430" checksum="AD0188E7A221B1CE" modified="2016-02-17" version="1">MTEVLVLYYSRGGSVARLARQIARGIGEVEGVSARLRTVPPVAAITQTAAPPVPEDGAPYVEPRDLDECAGLVLGSPTRFGNMAAPVKHWLDGLGAQWASGALVGKPAAVFTSTASMHGGQESTLLSMMVPLLHHGCVILGIPYTEPALSRTRGGGTPYGASHVAGAQDDPELSDDEAALARALGRRVAVLTAKVNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL13</accession>
    <name>A0A0S2DL13_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_19165</name>
        <name evidence="2" type="ORF">GLE_3902</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948634.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59244">
        <property type="protein sequence ID" value="ALN59244"/>
        <property type="gene ID" value="GLE_3902"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3902"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3839"/>
    <dbReference type="OrthoDB" id="2101537at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="19"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="83" mass="8894" checksum="92E66ACA790F10A3" modified="2016-02-17" version="1">MSLATTQCPPEYGEKSLAFWALGWTVLGLFALLGLALPVVAVRSTLGRGGWLRAAWILLACLAMLGCWIAGLSIFGVYFVMVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL51</accession>
    <name>A0A0S2DL51_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptide methionine sulfoxide reductase MsrB</fullName>
            <ecNumber evidence="3">1.8.4.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Peptide-methionine (R)-S-oxide reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">msrB</name>
        <name evidence="7" type="ORF">D9T17_08895</name>
        <name evidence="6" type="ORF">FE772_19195</name>
        <name evidence="5" type="ORF">GLE_3909</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">OH11</strain>
        </source>
    </reference>
    <reference evidence="6 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 10">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(R)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:24164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12314"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:45764"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MsrB Met sulfoxide reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.12" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000022">
        <property type="protein sequence ID" value="ROU07460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057950237.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000022.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3909"/>
    <dbReference type="EnsemblBacteria" id="ALN59251">
        <property type="protein sequence ID" value="ALN59251"/>
        <property type="gene ID" value="GLE_3909"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3909"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3846"/>
    <dbReference type="OMA" id="DEQWRAE"/>
    <dbReference type="OrthoDB" id="1650261at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033743">
        <property type="term" value="F:peptide-methionine (R)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01400">
        <property type="entry name" value="MsrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028427">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002579">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10173">
        <property type="entry name" value="PTHR10173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01641">
        <property type="entry name" value="SelR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00357">
        <property type="entry name" value="TIGR00357"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51790">
        <property type="entry name" value="MSRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MsrB" evidence="4">
        <location>
            <begin position="17"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW27446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROU07460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="142" mass="15833" checksum="67CBC65E5F8D871C" modified="2016-02-17" version="1">MSQHPVPGPAVPVEKTEAEWREQLSPEQYAICRCSATERAFTGRFWNHKDAGTYTCVACGEPLFASDTKYDSGSGWPSYYQPIRPEAVSEHADESHGMRRIEVKCARCQSHLGHVFPDGPRPTGLRYCINSASLDFEAKPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLF2</accession>
    <name>A0A0S2DLF2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Mutator MutT protein</fullName>
            <ecNumber evidence="6">3.6.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">mutT</name>
        <name evidence="6" type="ORF">GLE_4120</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4120"/>
    <dbReference type="EnsemblBacteria" id="ALN59462">
        <property type="protein sequence ID" value="ALN59462"/>
        <property type="gene ID" value="GLE_4120"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4120"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4062"/>
    <dbReference type="OMA" id="TGEPHGA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008413">
        <property type="term" value="F:8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00564">
        <property type="entry name" value="TMP_TenI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003561">
        <property type="entry name" value="Mutator_MutT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036206">
        <property type="entry name" value="ThiamineP_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022998">
        <property type="entry name" value="ThiamineP_synth_TenI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02581">
        <property type="entry name" value="TMP-TENI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51391">
        <property type="entry name" value="SSF51391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00586">
        <property type="entry name" value="mutt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="5">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="8-oxo-dGTP binding" evidence="2">
        <location>
            <begin position="25"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>8-oxo-dGTP</name>
            <dbReference type="ChEBI" id="CHEBI:77896"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR603561-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR603561-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="305" mass="32639" checksum="6A0D0477D4FFA1BE" modified="2016-02-17" version="1">MIRDARGRVLLTRRTEGRDLAGLWEFPGGKREPGETPEAALSRELHEELGIDAEIGAEVIRVPQIYPDKRLVLDVRHVRAWRGSARGREGQALAWVPPHKLASYAMPPADRPVVAALEQPERYLVTPEPEDDGVWLAGLSAALAAGVRRVQLRAPALAAGDRARWRQLAAAAAKRCRAAKAELLVNADLELALELGLGLHLRAAQLRELGERPLAAGLPLAASCHDADELRAAQALGCDFAVVGSVKPTPSHPSVLGIGWEAFAALRESVSLPIYAIGGLGPDDLAEARRHGAQGVAAIRSLWPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLM1</accession>
    <name>A0A0S2DLM1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CDP-diacylglycerol--serine O-phosphatidyltransferase</fullName>
            <ecNumber evidence="4">2.7.8.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Phosphatidylserine synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pssA</name>
        <name evidence="10" type="ORF">FE772_20595</name>
        <name evidence="9" type="ORF">GLE_4200</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a CDP-1,2-diacyl-sn-glycerol + L-serine = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16913"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="2.7.8.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.8" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948865.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4200"/>
    <dbReference type="EnsemblBacteria" id="ALN59542">
        <property type="protein sequence ID" value="ALN59542"/>
        <property type="gene ID" value="GLE_4200"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4200"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4142"/>
    <dbReference type="OMA" id="IFFDFFD"/>
    <dbReference type="OrthoDB" id="1232102at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003882">
        <property type="term" value="F:CDP-diacylglycerol-serine O-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004533">
        <property type="entry name" value="CDP-diaglyc--ser_O-PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00473">
        <property type="entry name" value="pssA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="204"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="227"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN59542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="262" mass="27952" checksum="B33B1BA7A633F2A1" modified="2016-02-17" version="1">MEPQPTPRPRGRGIYLLPNLFTTGGMFAGFYAIIAATQGRFDEACVAIFVAAILDGVDGRVARLTNTQSEFGVQYDSLADLISFGLAPALVMYHWALEATKLDGVIPGKIGWVGAFLYAACAALRLARFNSQVGQVDKRWFIGLASPAAAGLVASFVWTCHSFDLSGEELRYAALAVTVLAGLLMVSRVRYVSFKGSGPRNDRVPFLAILVVVAVLVAIAIDPPRVLLAIFAPYALSGPVQALWRRLRRTPETPPAGGAGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLM6</accession>
    <name>A0A0S2DLM6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Riboflavin synthase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Riboflavin synthase, alpha subunit</fullName>
            <ecNumber evidence="4 5">2.5.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ribE</name>
        <name evidence="5" type="ORF">FE772_20365</name>
        <name evidence="4" type="ORF">GLE_4153</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.5.1.9" evidence="4 5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948829.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4153"/>
    <dbReference type="EnsemblBacteria" id="ALN59495">
        <property type="protein sequence ID" value="ALN59495"/>
        <property type="gene ID" value="GLE_4153"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4153"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4095"/>
    <dbReference type="OMA" id="HFVTGHV"/>
    <dbReference type="OrthoDB" id="1276859at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004746">
        <property type="term" value="F:riboflavin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00402">
        <property type="entry name" value="Riboflavin_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001783">
        <property type="entry name" value="Lumazine-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026017">
        <property type="entry name" value="Lumazine-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098">
        <property type="entry name" value="PTHR21098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00677">
        <property type="entry name" value="Lum_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000498">
        <property type="entry name" value="Riboflavin_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00187">
        <property type="entry name" value="ribE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51177">
        <property type="entry name" value="LUMAZINE_BIND"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="98"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="98"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW27641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="207" mass="21729" checksum="C00B99C312DC4E4C" modified="2016-02-17" version="1">MFTGIIEGVGRLVSTQPIGGDVRLRIATGSLDFSEPKLGESIAVNGVCLTVIEFGADWYDADASTETLALTTLGALQAGAKVNLERAMRPSDRLGGHLVSGHVDGVGAVESVREDARAQRWRFRAPAPLLRYIAKKGSICVDGVSLTVNEVDSEGFEVALIPHTVANTAFSDSAIGAPVNLEIDLVARYVERLLGERPGAAGAEVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLS2</accession>
    <name>A0A0S2DLS2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948864.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4199"/>
    <dbReference type="EnsemblBacteria" id="ALN59541">
        <property type="protein sequence ID" value="ALN59541"/>
        <property type="gene ID" value="GLE_4199"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4199"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4141"/>
    <dbReference type="OMA" id="WLQAMGY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="147" mass="15724" checksum="F9B221805ADD1A84" modified="2016-02-17" version="1">MSGLWDAQQREWLQAMGYSVLALAGDEPAAAAPSRDAGEVARESERDRAAARAPGEAPNRGAHRADRRADERGEPTRGDGGRANAGAQAQRNQGAESALLRNLLRAARRASGDPEVQALFDPDALRAPAAKRALWPRLRALRRGARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLW7</accession>
    <name>A0A0S2DLW7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_4313</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948953.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4313"/>
    <dbReference type="EnsemblBacteria" id="ALN59654">
        <property type="protein sequence ID" value="ALN59654"/>
        <property type="gene ID" value="GLE_4313"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4313"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4252"/>
    <dbReference type="OMA" id="FNIERFY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007154">
        <property type="term" value="P:cell communication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038081">
        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003644">
        <property type="entry name" value="Calx_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001322">
        <property type="entry name" value="Lamin_tail_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036415">
        <property type="entry name" value="Lamin_tail_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007280">
        <property type="entry name" value="Peptidase_C_arc/bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03160">
        <property type="entry name" value="Calx-beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01345">
        <property type="entry name" value="DUF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00932">
        <property type="entry name" value="LTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04151">
        <property type="entry name" value="PPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141072">
        <property type="entry name" value="SSF141072"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74853">
        <property type="entry name" value="SSF74853"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51841">
        <property type="entry name" value="LTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595240" evidence="3">
        <location>
            <begin position="25"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="domain" description="LTD" evidence="4">
        <location>
            <begin position="18"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1167" mass="120357" checksum="BE56AF17C9E5569D" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM13</accession>
    <name>A0A0S2DM13_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4393</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4393"/>
    <dbReference type="EnsemblBacteria" id="ALN59734">
        <property type="protein sequence ID" value="ALN59734"/>
        <property type="gene ID" value="GLE_4393"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4393"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4332"/>
    <dbReference type="OMA" id="RACVAFF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="20"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="228" mass="25660" checksum="308C799AA96D8875" modified="2016-02-17" version="1">MTQRLSTDIDVDSHPGRKATISREDIIYAALKLVGPHRSVSSLSLREVAREAGIAPNSFYRQFRDTDELAVALIDLAGQSLRKIVGEARHRLTTRRSIVRSSIEAFMEQLRADDRLLHVLLREGTVGSDAFKRAVDRELSFFEEELRVDLIRLAALDQVELYEPALVARSITRLVFAMGATAMDMPREKDPELIEQMSAMVRMILAGSRAMAERGKAARGRAERNRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM51</accession>
    <name>A0A0S2DM51_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glycerol-3-phosphate acyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Acyl-PO4 G3P acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Acyl-phosphate--glycerol-3-phosphate acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">G3P acyltransferase</fullName>
            <shortName evidence="10">GPAT</shortName>
            <ecNumber evidence="10">2.3.1.275</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Lysophosphatidic acid synthase</fullName>
            <shortName evidence="10">LPA synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 12" type="primary">plsY</name>
        <name evidence="12" type="ORF">FE772_21205</name>
        <name evidence="11" type="ORF">GLE_4337</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>an acyl phosphate + sn-glycerol 3-phosphate = a 1-acyl-sn-glycero-3-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:34075"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57970"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="2.3.1.275"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10">Lipid metabolism; phospholipid metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Probably interacts with PlsX.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the PlsY family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.275" evidence="10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948973.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4337"/>
    <dbReference type="EnsemblBacteria" id="ALN59678">
        <property type="protein sequence ID" value="ALN59678"/>
        <property type="gene ID" value="GLE_4337"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4337"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4276"/>
    <dbReference type="OMA" id="ILGHNWP"/>
    <dbReference type="OrthoDB" id="1691856at2"/>
    <dbReference type="UniPathway" id="UPA00085"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043772">
        <property type="term" value="F:acyl-phosphate glycerol-3-phosphate acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01043">
        <property type="entry name" value="PlsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003811">
        <property type="entry name" value="G3P_acylTferase_PlsY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30309">
        <property type="entry name" value="PTHR30309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02660">
        <property type="entry name" value="G3P_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01207">
        <property type="entry name" value="G3P_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00023">
        <property type="entry name" value="TIGR00023"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="183"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN59678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW27787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="225" mass="23421" checksum="1A91AB6F4839E9EE" modified="2016-02-17" version="1">MPFSDLAPSLSAALAEPRSLALFAAAYALGSVSGSLVLGKLRGVDIRTQGSGNAGGTNALRTQGARFALGVVAIDIGKGALAAWLALRYAPLGDGLSVTAHGYLAAFAAVLGHVWPLWHGFRGGKGVATLVGGLLVLWPFVTPALLLVWGATIALSGYVGLASVIAALSLPLLAWYSDADAPRLWFCVAAAALVLFTHRGNLARLRAGTESRFSRARLLHRWRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM99</accession>
    <name>A0A0S2DM99_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 19">Adenosylcobinamide-GDP ribazoletransferase</fullName>
            <ecNumber evidence="7 19">2.7.8.26</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18 19">Cobalamin synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17 19">Cobalamin-5'-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19 20" type="primary">cobS</name>
        <name evidence="20" type="ORF">GLE_4081</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16 19">Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 19">
            <text>adenosylcob(III)inamide-GDP + alpha-ribazole 5'-phosphate = adenosylcob(III)alamin 5'-phosphate + GMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23560"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57918"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:60487"/>
            <dbReference type="ChEBI" id="CHEBI:60493"/>
            <dbReference type="EC" id="2.7.8.26"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 19">
            <text>adenosylcob(III)inamide-GDP + alpha-ribazole = adenosylcob(III)alamin + GMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16049"/>
            <dbReference type="ChEBI" id="CHEBI:10329"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:60487"/>
            <dbReference type="EC" id="2.7.8.26"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 19">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 19">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 7/7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="19">Cell membrane</location>
            <topology evidence="19">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 19">Belongs to the CobS family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.26" evidence="7 19"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948767.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4081"/>
    <dbReference type="EnsemblBacteria" id="ALN59423">
        <property type="protein sequence ID" value="ALN59423"/>
        <property type="gene ID" value="GLE_4081"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4081"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4023"/>
    <dbReference type="OMA" id="GHTGDTY"/>
    <dbReference type="OrthoDB" id="1996371at2"/>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00238"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051073">
        <property type="term" value="F:adenosylcobinamide-GDP ribazoletransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008818">
        <property type="term" value="F:cobalamin 5'-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00719">
        <property type="entry name" value="CobS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003805">
        <property type="entry name" value="CobS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34148">
        <property type="entry name" value="PTHR34148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02654">
        <property type="entry name" value="CobS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00317">
        <property type="entry name" value="cobS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 19" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 19" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="13 19" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 19 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="182"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00010561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00015850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00025228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00032605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00032853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ALN59423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="246" mass="25285" checksum="A07E4153478A5DCA" modified="2016-02-17" version="1">MRAALAAIGFLTRIPVPARVFADADAQRRALAWYPLAGALIGLLLCALAWSLQTRPPLLSAALLLIAWTALTGALHLDGLADTTDAWVGGLRADPQQSRARTLDIMKDPRSGPLAVTAVALLLLLKFAALASLPAPAWAALLLAPLLARAALTLAFLTTPYVRSGGLGQALAGAPRAGCIAALIVSAAACALAGWRGALALAAALLVFALWRRACLRRLQGMTGDTCGALAELTEAAVLAALALSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMB8</accession>
    <name>A0A0S2DMB8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4376</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59717">
        <property type="protein sequence ID" value="ALN59717"/>
        <property type="gene ID" value="GLE_4376"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4376"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4315"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="101"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="378" mass="40510" checksum="A02C7F94F727D4F1" modified="2016-02-17" version="1">MPADAGNRTGLAYHRRFIDLRRAVMGAARGHFGRTSGAILGLTLMIVAGGADAAAKPGARKPPKPAPDARLDVYAEPGERIDLGGGRKLNLRCSGQGRPTVLLEAGFGSDSLAWARSQPQIAERNRVCAYDRAGLGFSDGGPLPRDLTADVADLHALIEAADLDTPLILVGHSYGSQVVRRYDELHPKKVAALVLVDPPEQNVGEFSASYAKTEAAMAPRMLAMYRACEQGAREGRLGAARPPAELRNCLRPPNPNYSDKLNAAIRAWRSKPAFWETVITGSQDRLSLYGSAVAKSERHDGKPVIVLSAEQPYAGAPADDLKALTAAREQTHLALIGTSRYAKRVTIADSSHDIPNDQPAAPAIAVFEAMQMRKQMGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMY2</accession>
    <name>A0A0S2DMY2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59841">
        <property type="protein sequence ID" value="ALN59841"/>
        <property type="gene ID" value="GLE_4500"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4500"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4436"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="51" mass="5409" checksum="A6CC6215D4F75299" modified="2016-02-17" version="1">MEQKYIKAITKSDASILERAVASPEVKQLVVAFAKVAVPQLVKAFIGAPGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMY3</accession>
    <name>A0A0S2DMY3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4428</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59769">
        <property type="protein sequence ID" value="ALN59769"/>
        <property type="gene ID" value="GLE_4428"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4428"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="63" mass="7386" checksum="BFB74A93F3A5341A" modified="2016-02-17" version="1">MFDDRREAASGACIGHRVVHERERARRAGARARDCRAARSQARLRAVVAEKLRRRSSRRRRCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN61</accession>
    <name>A0A0S2DN61_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_13630</name>
        <name evidence="4" type="ORF">FE772_22995</name>
        <name evidence="2" type="ORF">GLE_4730</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000035">
        <property type="protein sequence ID" value="OPD63328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949268.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4730"/>
    <dbReference type="EnsemblBacteria" id="ALN60071">
        <property type="protein sequence ID" value="ALN60071"/>
        <property type="gene ID" value="GLE_4730"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63328">
        <property type="protein sequence ID" value="OPD63328"/>
        <property type="gene ID" value="BV903_13630"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4730"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4664"/>
    <dbReference type="OMA" id="FMYGHGF"/>
    <dbReference type="OrthoDB" id="2035522at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="5"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="139" mass="15677" checksum="8087FA56CC5971B8" modified="2016-02-17" version="1">MTTHAQLFVNLPVQDLDRSVAFYTQLGYSFNPQFTDENATCMLLGENLFAMLLVRPFFQTFTQKELIDPQRQVQTLVALPVPSREEVDALVDKAVAAGAKAHAPKDYGFMYQRAYDDLDGNTWEIFYMDANAEPSEALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN67</accession>
    <name>A0A0S2DN67_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Efflux pump membrane transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BV903_15865</name>
        <name evidence="9" type="ORF">FE772_22825</name>
        <name evidence="7" type="ORF">GLE_4689</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cell inner membrane</location>
            <topology evidence="2 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000041">
        <property type="protein sequence ID" value="OPD62947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949239.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4689"/>
    <dbReference type="EnsemblBacteria" id="ALN60030">
        <property type="protein sequence ID" value="ALN60030"/>
        <property type="gene ID" value="GLE_4689"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62947">
        <property type="protein sequence ID" value="OPD62947"/>
        <property type="gene ID" value="BV903_15865"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4689"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4624"/>
    <dbReference type="OMA" id="LMYMSSS"/>
    <dbReference type="OrthoDB" id="91817at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042908">
        <property type="term" value="P:xenobiotic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
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        <property type="entry name" value="HAE1"/>
    </dbReference>
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        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ACRIFLAVINRP"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="458"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="470"/>
            <end position="497"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="558"/>
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="932"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="1007"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1019"/>
            <end position="1041"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00010942"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN60030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD62947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW28053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="1064" mass="114397" checksum="64EFEB0B8AA08E02" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN81</accession>
    <name>A0A0S2DN81_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4659</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60000">
        <property type="protein sequence ID" value="ALN60000"/>
        <property type="gene ID" value="GLE_4659"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4659"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4595"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="37" mass="4163" checksum="AD8BB87AF93498CA" modified="2016-02-17" version="1">MAARRARNWDVDSGRGRGRRLFTEAAAARGICKRRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNQ1</accession>
    <name>A0A0S2DNQ1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aldehyde dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FE772_24275</name>
        <name evidence="8" type="ORF">GLE_5006</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3 6">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5006"/>
    <dbReference type="EnsemblBacteria" id="ALN60347">
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        <property type="gene ID" value="GLE_5006"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="293754at2"/>
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        <property type="component" value="Chromosome"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
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        <property type="entry name" value="Ald_DH_C"/>
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        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Aldehyde_DH_NAD(P)"/>
    </dbReference>
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        <property type="entry name" value="PTHR43570"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ALDH"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="7">
        <location>
            <begin position="25"/>
            <end position="442"/>
        </location>
    </feature>
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        </location>
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        <location>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR036492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
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        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN60347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW28299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="475" mass="52056" checksum="DC17C090CF09FA2E" modified="2016-02-17" version="1">MDILADTPIADLAATRERLRTAWQARKPDYAQRRADLIRLRDAFRAHIPQMDAAIRADFGHRSSHENLLSEAMITLAEIEHALSHLRAWMRPRRAAVGWRFWPARAQIRPEPVGVVGILSPWNYPVNLALVPLVSAIAAGNHVYLKPSEHTPRTSQFLRELLADVFPEDRVAVALGGPELGAAFSALPFDHLLFTGSTAVGRKVMAAAAPNLTPVTLELGGKAPALVCADYPLEQAAARIATGKWFNAGQTCIGVDYVLVDHARRDALVEALLAQLKARYGDMTAPQDYTRIINASQYARLASYLDDARARGVQVVEPFEDGSTREANAAQRLFPPTLVIEPGDDAQVMQHEIFGPILPVLSYRSLDEAIARINRLDRPLALYPFSRDSAQVDKILAQTLAGGVTVNDTLLHFGAHDLPFGGIGPSGIGAIHGRNGFDAFSKLLPVFYQRPWAGSDLLKPPYKGKIDAMIRFLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP51</accession>
    <name>A0A0S2DP51_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AAA family ATPase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Protein containing ATPase domain associated with various cellular activities (AAA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_12210</name>
        <name evidence="3" type="ORF">GLE_4999</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000029">
        <property type="protein sequence ID" value="OPD63680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949474.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000029.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4999"/>
    <dbReference type="EnsemblBacteria" id="ALN60340">
        <property type="protein sequence ID" value="ALN60340"/>
        <property type="gene ID" value="GLE_4999"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63680">
        <property type="protein sequence ID" value="OPD63680"/>
        <property type="gene ID" value="BV903_12210"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4999"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4927"/>
    <dbReference type="OMA" id="DRFMFAI"/>
    <dbReference type="OrthoDB" id="895310at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_3" evidence="1">
        <location>
            <begin position="50"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_lid_2" evidence="2">
        <location>
            <begin position="253"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD63680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="329" mass="35160" checksum="A6CE2E1048ACC03A" modified="2016-02-17" version="1">MSLDAAPLVPITGPALAERAAAVRDEVGKAFIGQADVLDQILIALLAGGHALLEGVPGLGKTLVVRALSKALDCGYARVQFTPDLMPSDISGHAVYDPKTESFNIRRGPVFTNLLLADEINRAPAKTQSALLEAMQELQVTIEGHSFELPPPFLTLATQNPVEQEGTYPLPEAQLDRFLLKVLIGYPTLADEKRMVAAVSLGRSASDFDLSQVQRVLGPEEIVAMQLGTALVRVDEAVIDYAVRIVAKTRDWAGIALGAGPRGSLGLVRAARAQAVLSGRDFVTPDDVREIAKPVLRHRIALAPELQIEGQSADDVLHALLATVEAPRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP58</accession>
    <name>A0A0S2DP58_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter, permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_5081</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5081"/>
    <dbReference type="EnsemblBacteria" id="ALN60422">
        <property type="protein sequence ID" value="ALN60422"/>
        <property type="gene ID" value="GLE_5081"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5081"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5008"/>
    <dbReference type="OMA" id="FGTQWYI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="335"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="378"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="412"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="512"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="33"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="344"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN60422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="545" mass="59470" checksum="3A7D4CE72E4FF975" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPL4</accession>
    <name>A0A0S2DPL4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">DNA-binding transcriptional regulator NtrC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Nitrogen regulation protein NR(I)</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 12" type="primary">ntrC</name>
        <name evidence="13" type="ORF">BV903_23350</name>
        <name evidence="12" type="ORF">GLE_5048</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">C3</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">B25</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000081">
        <property type="protein sequence ID" value="OPD61496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949514.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000081.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5048"/>
    <dbReference type="EnsemblBacteria" id="ALN60389">
        <property type="protein sequence ID" value="ALN60389"/>
        <property type="gene ID" value="GLE_5048"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61496">
        <property type="protein sequence ID" value="OPD61496"/>
        <property type="gene ID" value="BV903_23350"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5048"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4976"/>
    <dbReference type="OMA" id="DWTGNIR"/>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009399">
        <property type="term" value="P:nitrogen fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010114">
        <property type="entry name" value="Transcript_reg_NtrC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01818">
        <property type="entry name" value="ntrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0010">Activator</keyword>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0535">Nitrogen fixation</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0678">Repressor</keyword>
    <keyword evidence="7 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="9" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Response regulatory" evidence="11">
        <location>
            <begin position="5"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="10">
        <location>
            <begin position="141"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="8">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN60389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OPD61496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="468" mass="50292" checksum="C0F8EF29FA734993" modified="2016-02-17" version="1">MSAARIWVVDDDRSVRFVLATALREAGYAVDGFENAADALDALEQRGAPDLLFTDVRMPGDGGLALLEKLKARAPALPVVVMSAYTDVASTAGAFRGGAQEFLSKPFDLDDAVALAARTLSTSAPVAEPPPAADAAPADALIGDTPAMLTLFRAIGRLAQAPLSVLVTGETGTGKELVARALHRESPRAQRPFVALNTAAIPAELLESELFGHEAGAFTGAQRRHVGRFEQADGGSLFLDEIGDMPLPLQTRLLRVLAEGEFFRVGGRELIRVDVRVIAATHQDLEGLVAQGRFRADLLHRLDVVRLRLPPLRERRGDVAQLAERFLAAAAQRFGTPLKRLSKPALERLMAHDWPGNVRELENVCWRLAALAPGDAIAREDLDQALGAEPARAADAGEAWEALLSAWARAQLAEGRANLHADARERFDRALLEAALAHTGGRRTEAAARLGLGRNTLTRKLGPGRKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPN6</accession>
    <name>A0A0S2DPN6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4866</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60207">
        <property type="protein sequence ID" value="ALN60207"/>
        <property type="gene ID" value="GLE_4866"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4866"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4798"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="67" mass="7319" checksum="559B5BB8F88C2898" modified="2016-02-17" version="1">MRRSRDGAVAARAAPTGAPAGFVADCRSDASRDREPATTTKLAPQQRRRGRGSRRSHRGSGRLRFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPU3</accession>
    <name>A0A0S2DPU3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA-binding response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Photosynthetic apparatus regulatory protein RegA</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">regA</name>
        <name evidence="4" type="ORF">BV903_11195</name>
        <name evidence="5" type="ORF">FE772_24865</name>
        <name evidence="3" type="ORF">GLE_5128</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD63864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949576.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5128"/>
    <dbReference type="EnsemblBacteria" id="ALN60469">
        <property type="protein sequence ID" value="ALN60469"/>
        <property type="gene ID" value="GLE_5128"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63864">
        <property type="protein sequence ID" value="OPD63864"/>
        <property type="gene ID" value="BV903_11195"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5128"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5053"/>
    <dbReference type="OMA" id="RRLEWEH"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="17"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="66"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD63864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW28402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="198" mass="20888" checksum="0B25F3EF719CAF01" modified="2016-02-17" version="1">MNASTPPRAVLSGTPGSGLIVDDDETYAATLQRSLARRGIQARTAGSVRQALDLALQQAPSFALVDLKLGADSGLQLIRPLRELRADMRIVLVTGYASVATAVDAIKRGADDYLPKPASVGAILAAIGVDAPDAAAAPVQAPDTMMPLRRLEWEHIQQALNDTGGNISATARLLGMHRRSLQRKLGKRPGPERSVVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ45</accession>
    <name>A0A0S2DQ45_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5293</name>
    </gene>
    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5293"/>
    <dbReference type="EnsemblBacteria" id="ALN60634">
        <property type="protein sequence ID" value="ALN60634"/>
        <property type="gene ID" value="GLE_5293"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5293"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5211"/>
    <dbReference type="OMA" id="AQPQSID"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595124" evidence="1">
        <location>
            <begin position="26"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="211" mass="20461" checksum="F38946D70035905B" modified="2016-02-17" version="1">MNARPRPLRHAPLWLAGCLLATAIAGDGRAQDAPLDAPLDRAEVGAAGRGLDGRAAINQAAGAGNAQANQAALSLSPAGLALASASAGQRVERPGPAALARDAQARIGAGAFDGAHGLLQLNQAAGAGNVQLNRFALARGAASALDDAALAAIAGPPAEAAPSRAAPGARQADIAADALRGGQGVLQLNQTAGTGNASVNAIVLRLPGSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQI3</accession>
    <name>A0A0S2DQI3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome C5</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="10">Cytochrome c5 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BV903_05315</name>
        <name evidence="11" type="ORF">FE772_00380</name>
        <name evidence="9" type="ORF">GLE_5427</name>
    </gene>
    <organism evidence="9 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">C3</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000010">
        <property type="protein sequence ID" value="OPD64914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949800.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5427"/>
    <dbReference type="EnsemblBacteria" id="ALN60768">
        <property type="protein sequence ID" value="ALN60768"/>
        <property type="gene ID" value="GLE_5427"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64914">
        <property type="protein sequence ID" value="OPD64914"/>
        <property type="gene ID" value="BV903_05315"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5427"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5343"/>
    <dbReference type="OMA" id="TQERIAP"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002323">
        <property type="entry name" value="Cyt_CIE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40942">
        <property type="entry name" value="PTHR40942"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2 6" id="KW-0349">Heme</keyword>
    <keyword evidence="5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="8">
        <location>
            <begin position="87"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN60768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD64914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW24352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="171" mass="17801" checksum="D7A567ECFE1357A8" modified="2016-02-17" version="1">MRNYDLEFLKKFSMVIGFLMLVTLGLMIAAYFVHKQLPQEVDPRAAQRTENRIAPTGAVYAGATGAAAQQAAVAAAAAKAASQVAYGGTLDGKVIFDSLCAGCHKSGAGGAPTLDASHWATRLPKGKDTLHKHAIEGFTGSTGIMPAKGGNPALTNEQVSATVDWMLGNIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQJ5</accession>
    <name>A0A0S2DQJ5_LYSEN</name>
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    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="69"/>
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            <taxon>Proteobacteria</taxon>
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    <reference evidence="2 3" key="1">
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60870">
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    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5529"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5447"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="69" mass="7856" checksum="9B87BD705E9541A0" modified="2016-02-17" version="1">MTRFRDDRRAAGACSSRSSRQPQIQPMSVQSFSSFSSRLLCSRVACLGVRAARRGCLRFVFFILLRPRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQQ8</accession>
    <name>A0A0S2DQQ8_LYSEN</name>
    <protein>
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            <fullName evidence="1">Uncharacterized protein</fullName>
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        </lineage>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60761">
        <property type="protein sequence ID" value="ALN60761"/>
        <property type="gene ID" value="GLE_5420"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5420"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5336"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="51" mass="5514" checksum="2916C5F512F91114" modified="2016-02-17" version="1">MKAACSDCAATRAGLRCVPALVRRASAPRRGAFRATVHNRNAPRTHEPARD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQX0</accession>
    <name>A0A0S2DQX0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">GLE_5519</name>
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    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60860">
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        <property type="gene ID" value="GLE_5519"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5519"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5433"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="74" mass="7974" checksum="1F2E1E241AD2F9C2" modified="2016-02-17" version="1">MKQNDVFKECLTQLPESVLADFGPLTGGVLSTLAQQELQRRAALALQSIPGDYVVDLLLGRAYPSKTVADVLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQZ0</accession>
    <name>A0A0S2DQZ0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    <organism evidence="1 3">
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        <lineage>
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    <reference evidence="1 3" key="1">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 4" key="2">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="ALN60857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24416.1"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="107" mass="12690" checksum="4166DE088772976C" modified="2016-02-17" version="1">MSTTLLPPYQFRIRFSRNPKNYRAMMRELSGYYVEPELAWVIERKTMTQAEYRAFERDFTNPQPWIWELNSRPGHCIMVVAPRMPTLYVRAEGTDHASYVGLPSDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA50</accession>
    <name>A0A0S2DA50_LYSEN</name>
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            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Feng T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">YC36</strain>
        </source>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="310" mass="35524" checksum="387A0B4F8AE9FDC9" modified="2016-02-17" version="1">MLKLYLRWFDREPVGALLPAKSSRELIDLDALGAFTAPRRTRRYRCVDCGLLDTVHVYPAGDHLLHCQQCGSRSIDLQDKPYQTVQLRHEWLPRTLSKLMVGDVTSPQVLVPNRVWHLADIDSPRGQVAVMLVRSGWQCDYAAVASVLRKFGRPRQIVLTTSRIEQEELNSAGRVVIPLASVAKLDAQGLWLERETLIEHYLRGVNQARKLLLHPTLKSDQHLWFELGPDNAWLRVNSRTVRLWGKQRLFVASIARAHIRNQPHRRLADAVNDAGYEGDVRSLHQICSRRDFREVIGIADGFVWIRDDVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA91</accession>
    <name>A0A0S2DA91_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="1" type="ORF">GLE_0068</name>
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    <reference evidence="1 3" key="1">
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                <person name="Kobayashi D.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_0068"/>
    <dbReference type="EnsemblBacteria" id="ALN55427">
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        <property type="gene ID" value="GLE_0068"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0068"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.74"/>
    <dbReference type="OrthoDB" id="1784317at2"/>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="114" mass="13745" checksum="F803CE9B1A8579CC" modified="2016-02-17" version="1">MSNHDETEVGAAAFVQAIDPGEYREHFHREFRFAPYYSAGREWPDYEPAYRYGYDRYLHCGGRRFEEVEETLAREWNHCRAASRLHWTEAREAVRDGWHHIERNLPHALDRPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAB6</accession>
    <name>A0A0S2DAB6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55479">
        <property type="protein sequence ID" value="ALN55479"/>
        <property type="gene ID" value="GLE_0120"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0120"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.123"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="83" mass="8619" checksum="11D11C96DF49E8AB" modified="2016-02-17" version="1">MFESPASTAPMDGPMDGPAVGRRRGSARAETPAPPAQRAARGSRSRGGRIGAAAPARPTMRPSRARARPPVQRQFGGDSSLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAG2</accession>
    <name>A0A0S2DAG2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0066</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0066"/>
    <dbReference type="EnsemblBacteria" id="ALN55425">
        <property type="protein sequence ID" value="ALN55425"/>
        <property type="gene ID" value="GLE_0066"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0066"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.72"/>
    <dbReference type="OMA" id="GHWLWSA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032713">
        <property type="entry name" value="EmrE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13536">
        <property type="entry name" value="EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="294"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="330" mass="34456" checksum="26B702DF78130778" modified="2016-02-17" version="1">MSARRHALYAVLIALASALFFTCTYVLNRAAADGGGHWAWTASLRYLFTLPMLLAVMPLQGGIGPVWRAIRAHPGPWLAWSAVGFGLFYLCLSYAAASGPSWLVAATFQLTVIAGMLCAPLLYRDERARVPLPALLVGAAIVAGVLLMQLGHGGGRLDRAGWIALICVAVAAFAYPLGNRGLLLHLERAGIELNATQRVFGMTLASQPLWWASALYAGVEAGAPTAAQAWLAAGVALGAGVIATILFFQATGMVRNDPTALAATEAMQAAEIVFATAIGALWLGEAWPRGQALAGAGIVVLGIVGFSAVAARAAAGNERRLRRLRSDRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAJ0</accession>
    <name>A0A0S2DAJ0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_01925</name>
        <name evidence="3" type="ORF">GLE_0215</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0215"/>
    <dbReference type="EnsemblBacteria" id="ALN55574">
        <property type="protein sequence ID" value="ALN55574"/>
        <property type="gene ID" value="GLE_0215"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0215"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.217"/>
    <dbReference type="OMA" id="VDRTTMT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="2">
        <location>
            <begin position="73"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="224" mass="24600" checksum="A13EF18BDAA733C3" modified="2016-02-17" version="1">MSAEPDTHTDGTPHGASKLQHPPGAPDGSVVLPLPPNVPRVKPSRLARWLGRAILRLGGWRMVGQLPDIPRAVLIGIPHSSNWDGVWAFAAKAAMGLNVNIIAKESLFKVPVVGFMLRRFGVIPINRNAAHGVIDQAVAMIKGAEKFWLGIAPEGTRKRVEKWKAGFWKIAKNADVPVVLAYFHYPDKVIGIGPAFHLGEDMDADMRRIREYCRPFIGKNRGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAP8</accession>
    <name>A0A0S2DAP8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Exodeoxyribonuclease III</fullName>
            <ecNumber evidence="3">3.1.11.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">xth</name>
        <name evidence="4" type="ORF">FE772_02115</name>
        <name evidence="3" type="ORF">GLE_0259</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.2" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945909.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0259"/>
    <dbReference type="EnsemblBacteria" id="ALN55618">
        <property type="protein sequence ID" value="ALN55618"/>
        <property type="gene ID" value="GLE_0259"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0259"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.260"/>
    <dbReference type="OMA" id="DCICVQE"/>
    <dbReference type="OrthoDB" id="1893707at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008853">
        <property type="term" value="F:exodeoxyribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020847">
        <property type="entry name" value="AP_endonuclease_F1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748">
        <property type="entry name" value="PTHR22748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00633">
        <property type="entry name" value="xth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00726">
        <property type="entry name" value="AP_NUCLEASE_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51435">
        <property type="entry name" value="AP_NUCLEASE_F1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="5"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="257" mass="29302" checksum="DA8FCFBEE371F8DB" modified="2016-02-17" version="1">MRIISFNANGLRSATTKGFFDWFKAQDADVLCVQETKAQEHQLAGPEFLPEGYRAYFRDAITKKGYSGVAIYAKREPDEVRTALGWAPFDDEGRYIEARFGNLSVVSFYIPSGSSGELRQGFKFEVMEWLKPILDEWLASGRDYVLCGDWNIVRSRLDIKNWTSNQKNSGCLPPERDWLNGVCADDSGWVDAYRALKAEGQDYTWWSNRGAARANDVGWRIDYQFATPSLRGKLRGCSILKEPRFSDHAPFTVDYDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAY0</accession>
    <name>A0A0S2DAY0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha,alpha-phosphotrehalase</fullName>
            <ecNumber evidence="2">3.2.1.93</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0338</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.93" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="KEGG" id="lez:GLE_0338"/>
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    <dbReference type="Proteomes" id="UP000061569">
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        <property type="project" value="UniProtKB-EC"/>
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    </dbReference>
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        <property type="entry name" value="O16G_dom_2"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
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    <feature type="domain" description="Aamy" evidence="1">
        <location>
            <begin position="4"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="533" mass="59515" checksum="6BAD071C2463778C" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB15</accession>
    <name>A0A0S2DB15_LYSEN</name>
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        <recommendedName>
            <fullName evidence="4">Cytochrome c oxidase assembly protein CtaG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">BV903_23705</name>
        <name evidence="12" type="ORF">GLE_0289</name>
    </gene>
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            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">C3</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">B25</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.</text>
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    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
            <orientation evidence="2">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the COX11/CtaG family.</text>
    </comment>
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        <property type="protein sequence ID" value="ALN55647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF110111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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            <begin position="29"/>
            <end position="48"/>
        </location>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN55647.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="OPD61430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="211" mass="22945" checksum="07EC828DE19486F4" modified="2016-02-17" version="1">MSAARDPRESPSQDLAETRRQASPKMVKLMVGVALGAFAFTFALVPLYRIACEKVFGIRLERGVAEADVGGRAVGDRIVTVQFDGSVNSKLPWEFRPHVISMKVRPGEQYETTYYARNTSDAAIVGSASPSVAPARASGYFNKTECFCFTAQTLQAGESREMPVRFIVDPNLPEGVETLTLSYTFFKNDVLTARLQQGAVSKTPSSPLAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB49</accession>
    <name>A0A0S2DB49_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55767">
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        <property type="gene ID" value="GLE_0409"/>
    </dbReference>
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    <dbReference type="PATRIC" id="fig|69.6.peg.406"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="141" mass="15041" checksum="06927CEC460C497A" modified="2016-02-17" version="1">MSSIAAGRVAPAAVCETPRRQMRASAPRRDPPPANGRRSRRSRSAALRDTGSPMRAASTPRTGRRPSGSIPERHDAHSGIALSPKRRPPSAFSLGAQPDGEAICPSDIRLSDGARRIRRGRARSTHSTRAASSNAMNTANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBF8</accession>
    <name>A0A0S2DBF8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_03285</name>
        <name evidence="2" type="ORF">GLE_0512</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55870">
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        <property type="gene ID" value="GLE_0512"/>
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    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="79" mass="9427" checksum="2837DF3715B5B1BB" modified="2016-02-17" version="1">MRATRWIRQFHRWTSVVFFLCVIATTIALAQERPLLWMSYLPLAPLALLALTGLYLFALPYLPQRELPRREDWRDEAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBK2</accession>
    <name>A0A0S2DBK2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_03475</name>
        <name evidence="1" type="ORF">GLE_0548</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW24871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946117.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0548"/>
    <dbReference type="EnsemblBacteria" id="ALN55906">
        <property type="protein sequence ID" value="ALN55906"/>
        <property type="gene ID" value="GLE_0548"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0548"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.542"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="262" mass="29048" checksum="1F317EE6F4D14C3D" modified="2016-02-17" version="1">MIPDNDSTPVIETDRLMMQAQTVVETPIAAARGKLMQASTVERDQPADAPLPRTVAWIRNFLARPHPDVGRPGPVCPFTPTALALDTIWLAEIQDRDVSLDRIVELISVYRDLFGEIEPRTGQVAINKTVLIVFPHLGDDAAAFVDEVQQQLKPSFVDLGLMLGEFHASNESPGLRNPDFRPLRSPVPMLAIRQMVETDLPFLRRSLDTAQVRSQFLRSYLRRLGGTVRRNYFDQAVKALVEAEIELQAQSAAAAKPTTASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC48</accession>
    <name>A0A0S2DC48_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2-acylglycerophosphoethanolamine acyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.51</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="4">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">aas</name>
        <name evidence="4" type="ORF">FE772_04370</name>
        <name evidence="3" type="ORF">GLE_0736</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.51" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946260.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0736"/>
    <dbReference type="EnsemblBacteria" id="ALN56094">
        <property type="protein sequence ID" value="ALN56094"/>
        <property type="gene ID" value="GLE_0736"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0736"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.724"/>
    <dbReference type="OMA" id="GNGMVEM"/>
    <dbReference type="OrthoDB" id="961884at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003841">
        <property type="term" value="F:1-acylglycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="334"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="380"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="403"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="PlsC" evidence="2">
        <location>
            <begin position="456"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="627" mass="68740" checksum="98CE48205F2A8BBE" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC76</accession>
    <name>A0A0S2DC76_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Biotin carboxyl carrier protein of acetyl-CoA carboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">accB</name>
        <name evidence="9" type="ORF">BV903_19905</name>
        <name evidence="10" type="ORF">FE772_04520</name>
        <name evidence="8" type="ORF">GLE_0768</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000059">
        <property type="protein sequence ID" value="OPD62151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946285.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000059.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0768"/>
    <dbReference type="EnsemblBacteria" id="ALN56126">
        <property type="protein sequence ID" value="ALN56126"/>
        <property type="gene ID" value="GLE_0768"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62151">
        <property type="protein sequence ID" value="OPD62151"/>
        <property type="gene ID" value="BV903_19905"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0768"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.757"/>
    <dbReference type="OMA" id="IKSPIIG"/>
    <dbReference type="OrthoDB" id="1938042at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001249">
        <property type="entry name" value="AcCoA_biotinCC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01071">
        <property type="entry name" value="ACOABIOTINCC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00531">
        <property type="entry name" value="BCCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0092">Biotin</keyword>
    <keyword evidence="5" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="7">
        <location>
            <begin position="85"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN56126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD62151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW25044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="161" mass="17004" checksum="ED0456E048845390" modified="2016-02-17" version="1">MDLRKIKKLIDLLEESNLAEIEIKEGEESVRLARAPKGSYAVAAPMAPVYAAPEPRAAQPMPMQSPTEAATGGSAKALGNDLPDGHVVRAPMVGTFYTSPAPDKPSFVSVGQTVKAGDTLAIIEAMKMFNPIEADVSGTVLKILAESGQPIEFDQPLFVIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCH9</accession>
    <name>A0A0S2DCH9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cell division protein ZapA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Z ring-associated protein ZapA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">zapA</name>
        <name evidence="9" type="ORF">BV903_19635</name>
        <name evidence="11" type="ORF">D9T17_22835</name>
        <name evidence="10" type="ORF">FE772_05095</name>
        <name evidence="8" type="ORF">GLE_0885</name>
    </gene>
    <organism evidence="8 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 12">C3</strain>
        </source>
    </reference>
    <reference evidence="9 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">OH11</strain>
        </source>
    </reference>
    <reference evidence="10 15" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer. Interacts with FtsZ.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ZapA family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000057">
        <property type="protein sequence ID" value="OPD62205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000056">
        <property type="protein sequence ID" value="ROU04684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946369.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000056.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0885"/>
    <dbReference type="EnsemblBacteria" id="ALN56243">
        <property type="protein sequence ID" value="ALN56243"/>
        <property type="gene ID" value="GLE_0885"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62205">
        <property type="protein sequence ID" value="OPD62205"/>
        <property type="gene ID" value="BV903_19635"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0885"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.874"/>
    <dbReference type="OMA" id="NICYELH"/>
    <dbReference type="OrthoDB" id="1802106at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007838">
        <property type="entry name" value="Cell_div_ZapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036192">
        <property type="entry name" value="Cell_div_ZapA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042233">
        <property type="entry name" value="Cell_div_ZapA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34981">
        <property type="entry name" value="PTHR34981"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05164">
        <property type="entry name" value="ZapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102829">
        <property type="entry name" value="SSF102829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0717">Septation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00026068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN56243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD62205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW25133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROU04684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="101" mass="11299" checksum="7DE0A02FECCDB227" modified="2016-02-17" version="1">MSTTSEAVSIRLLDREYTVGCEPNEREDLLAAARMLDGKMREIRGGNRMAALDRVAVLAALNFAHELQQLRGESGGRERELARTLDDLHRKLDSLFDAASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCN8</accession>
    <name>A0A0S2DCN8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Amino acid carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">acgS</name>
        <name evidence="9" type="ORF">GLE_0746</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0746"/>
    <dbReference type="EnsemblBacteria" id="ALN56104">
        <property type="protein sequence ID" value="ALN56104"/>
        <property type="gene ID" value="GLE_0746"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0746"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.734"/>
    <dbReference type="OMA" id="GMATKFV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015655">
        <property type="term" value="F:alanine:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001463">
        <property type="entry name" value="Na/Ala_symport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30330">
        <property type="entry name" value="PTHR30330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01235">
        <property type="entry name" value="Na_Ala_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00175">
        <property type="entry name" value="NAALASMPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00835">
        <property type="entry name" value="agcS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0769">Symport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="244"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="310"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="352"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="380"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="418"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="482" mass="51210" checksum="7D724F455B4D30D9" modified="2016-02-17" version="1">MLDAIETALAPVIGAINHVLWDYFLTYGLLLVGLYFTVRLRFLQVRRFPHMLQVIGRGTDGDSSGISPFQALCTSLASRVGTGNLAGVAIALSLGGPGALFWMWCTAMLGMATAYAESALAQLYKVRDENGQYRGGPSYYMSRGLKKPWMGVAFALCLLLTYGLVFSSVHANAMAQSLHSAFGLSQLQIASGLVLLTAVIIFGGLRAIARFAEWVVPFMSLGYLLLAGWVVLTHLPQVPAVLTLIVRSAFGLDAAAGGVLGGLAVAMLQGVKRGLYSNEAGMGSAPNVAAAATPVPHHPSSQGLVQSLGVFIDTLMICSATGFVILLSGVLGQGGDGVQITQAAMTTFFGGWGTYFVAIALFFFAFTTIIGNYSYAESNLLYLGGGAKSLFVLRVAALAVIVWGVYSKVELVWNAADAAMALMASINLVAIVMLSGVVVKLTRDYDRQLREGKSPEFHIAQYAELGDGVDHEIWRERNKPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCT2</accession>
    <name>A0A0S2DCT2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FAD dependent oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Glycerol-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="8 9">1.1.5.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FE772_04740</name>
        <name evidence="8" type="ORF">GLE_0815</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.5.3" evidence="8 9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946316.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0815"/>
    <dbReference type="EnsemblBacteria" id="ALN56173">
        <property type="protein sequence ID" value="ALN56173"/>
        <property type="gene ID" value="GLE_0815"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0815"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.804"/>
    <dbReference type="OMA" id="TFCGVRV"/>
    <dbReference type="OrthoDB" id="360065at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009331">
        <property type="term" value="C:glycerol-3-phosphate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052591">
        <property type="term" value="F:sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.870">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031656">
        <property type="entry name" value="DAO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038299">
        <property type="entry name" value="DAO_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000447">
        <property type="entry name" value="G3P_DH_FAD-dep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985">
        <property type="entry name" value="PTHR11985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16901">
        <property type="entry name" value="DAO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01001">
        <property type="entry name" value="FADG3PDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="6">
        <location>
            <begin position="10"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="DAO_C" evidence="7">
        <location>
            <begin position="390"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN56173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW25081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="501" mass="56466" checksum="C3F1B76DEB080901" modified="2016-02-17" version="1">MTEAEAPTADLLIVGGGINGAAIARDAAGRGLSVVLCERGDIASHTSSASTKLIHGGLRYLEQFEFALVGKALAERKRLLRMAPHIIWPLRFVLPHQPHLRPAWMIRIGLFLYDRLGGRRSRELPGSRSVNLRKHIAGRPLREEFSRGFVYSDAWVQDARLCVLNAMDAAERGAQVWVRTACIGAERGARHWQAQLRGPDGALRQVRARALVNATGPWAASFLDQVAHVAHQRNLRLIKGSHIVVPRLFDHDHAYIFQQPDRRIVFAIPYEHDYTLIGTTDVDYREDPSAPRISTQEIDYLCAAATRYFQRPVLAEDVVWTYSGVRPLLDDDSDKASQVTRDYVLDLDREGAPLLSVFGGKITTARKLAEEACDTLAPLLDNRRGTWTGASKLPGGDLPDADFEAFFEDFSLRRPWLPDPLAYRLCRNYGSRALRIVESCVRLEDLGERFGADLYRAEVDYLIDFEWARTAEDILWRRSKLGLRFDAAGREALQRYVAQRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD55</accession>
    <name>A0A0S2DD55_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Hemin uptake protein HemP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">hemP</name>
        <name evidence="2" type="ORF">FE772_05880</name>
        <name evidence="1" type="ORF">GLE_1061</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1061"/>
    <dbReference type="EnsemblBacteria" id="ALN56419">
        <property type="protein sequence ID" value="ALN56419"/>
        <property type="gene ID" value="GLE_1061"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1061"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1050"/>
    <dbReference type="OMA" id="EIMIRHD"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019600">
        <property type="entry name" value="Hemin_uptake_protein_HemP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10636">
        <property type="entry name" value="hemP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="82" mass="8572" checksum="94D9572112B91F4E" modified="2016-02-17" version="1">MSLRNPVLQLKPRTDRSLAVVAPPVAAVAPAAAAASAVVAAAQGGLVESAALLRGAREVLIRHGGEVYRLRHTRNDKLILTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDB9</accession>
    <name>A0A0S2DDB9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA-binding response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="10">DNA-binding response regulator, OmpR family, contains REC and winged-helix (WHTH) domain</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Response regulator transcription factor</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Transcriptional regulatory protein, C terminal</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Two-component system response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BV903_23640</name>
        <name evidence="9" type="ORF">D9T17_21895</name>
        <name evidence="8" type="ORF">FE772_05710</name>
        <name evidence="5" type="ORF">GLE_1023</name>
        <name evidence="6" type="ORF">LEN_3888</name>
        <name evidence="10" type="ORF">SAMN05421681_102574</name>
    </gene>
    <organism evidence="5 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 11">C3</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2016" name="DNA Res." volume="0" first="0" last="0">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer, Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M497-1</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="3">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">ATCC 29487</strain>
        </source>
    </reference>
    <reference evidence="6 14" key="4">
        <citation type="journal article" date="2017" name="DNA Res." volume="24" first="169" last="177">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
            <dbReference type="PubMed" id="28065880"/>
            <dbReference type="DOI" id=".1093/dnares/dsw055"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 14">M497-1</strain>
        </source>
    </reference>
    <reference evidence="7 13" key="5">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 13">B25</strain>
        </source>
    </reference>
    <reference evidence="9 15" key="6">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 15">OH11</strain>
        </source>
    </reference>
    <reference evidence="8 16" key="7">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 16">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP014940">
        <property type="protein sequence ID" value="BAV99375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000083">
        <property type="protein sequence ID" value="OPD61465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000055">
        <property type="protein sequence ID" value="ROU04778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNOG01000002">
        <property type="protein sequence ID" value="SDW69417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946468.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000055.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1023"/>
    <dbReference type="EnsemblBacteria" id="ALN56381">
        <property type="protein sequence ID" value="ALN56381"/>
        <property type="gene ID" value="GLE_1023"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAV99375">
        <property type="protein sequence ID" value="BAV99375"/>
        <property type="gene ID" value="LEN_3888"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61465">
        <property type="protein sequence ID" value="OPD61465"/>
        <property type="gene ID" value="BV903_23640"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDW69417">
        <property type="protein sequence ID" value="SDW69417"/>
        <property type="gene ID" value="SAMN05421681_102574"/>
    </dbReference>
    <dbReference type="KEGG" id="lem:LEN_3888"/>
    <dbReference type="KEGG" id="lez:GLE_1023"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1011"/>
    <dbReference type="OMA" id="DNTLNTH"/>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000183696">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000218824">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="2"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="125"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="125"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAV99375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD61465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW25228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROU04778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="SDW69417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000183696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000218824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="226" mass="25071" checksum="C3A1282D8E2888BF" modified="2016-02-17" version="1">MRILVIEDNQDIAANLGDFLEDRGHTVDFAADGITGLHLAVVHDFDAIVLDLNLPGIDGLEVCRKLRNEARKQTPVLMLTARDSLDNKLAGFDSGADDYLIKPFALQEVEVRLNALSRRGRGVQTRVLNAADLEYNLDTLEVRRQGKLLQLNPTALKILQALMEASPAVVTRQELETRVWGEELPDSDSLRVHIHGLRAVVDKPFDTPLIQTRHGIGYRIAAPENG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDH2</accession>
    <name>A0A0S2DDH2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nuclear protein SET</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">SET domain-containing protein-lysine N-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_06815</name>
        <name evidence="7" type="ORF">GLE_1262</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="69.GLE_1262"/>
    <dbReference type="EnsemblBacteria" id="ALN56619">
        <property type="protein sequence ID" value="ALN56619"/>
        <property type="gene ID" value="GLE_1262"/>
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    <dbReference type="KEGG" id="lez:GLE_1262"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF82199"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 8" id="KW-0489">Methyltransferase</keyword>
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    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="5">
        <location>
            <begin position="3"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="6">
        <location>
            <begin position="135"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="143"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="154"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN56619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW25415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="182" mass="20638" checksum="8DCC6D1408BAF006" modified="2016-02-17" version="1">MPRKIAARRSAIHGNGVFAVAPIAKGERVIEYKGRRRTHEEADAGDTGDADSGHTFLFTLNDEYVIDANYEGNTARWINHSCSPNCEAVLNEDEGDDRRLDQVFIEAIRDIAPGEELSYNYGITLAEKHTKELKKIWECRCGSPDCTGTMLQPKKDKKKKKKDKDKKKDKKKKKDKKGKNKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDQ8</accession>
    <name>A0A0S2DDQ8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56592">
        <property type="protein sequence ID" value="ALN56592"/>
        <property type="gene ID" value="GLE_1235"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1235"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1219"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="42" mass="4616" checksum="59EA6A16D8B8913F" modified="2016-02-17" version="1">MEREPRAGVHERADKNAPPPSRRAPFGLQLRAFRRGFAGAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDT1</accession>
    <name>A0A0S2DDT1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="14">C-type cytochrome</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="13">Gluconate 2-dehydrogenase cytochrome c subunit</fullName>
            <ecNumber evidence="13">1.1.99.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">FE772_06185</name>
        <name evidence="13" type="ORF">GLE_1130</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">C3</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </cofactor>
        <text evidence="8">Binds 3 heme c groups covalently per subunit.</text>
    </comment>
    <comment type="PTM">
        <text evidence="9">Binds 3 heme groups per subunit.</text>
    </comment>
    <dbReference type="EC" id="1.1.99.3" evidence="13"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW25310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946543.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1130"/>
    <dbReference type="EnsemblBacteria" id="ALN56488">
        <property type="protein sequence ID" value="ALN56488"/>
        <property type="gene ID" value="GLE_1130"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1130"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1115"/>
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    <dbReference type="OrthoDB" id="1297285at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:gluconate 2-dehydrogenase (acceptor) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014353">
        <property type="entry name" value="Membr-bd_ADH_cyt_c"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000018">
        <property type="entry name" value="Mb_ADH_cyt_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2 8 10" id="KW-0349">Heme</keyword>
    <keyword evidence="6 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="9"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="12">
        <location>
            <begin position="44"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="12">
        <location>
            <begin position="189"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="12">
        <location>
            <begin position="317"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="8">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>3</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000018-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000018-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN56488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW25310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="429" mass="45670" checksum="51133C013056673D" modified="2016-02-17" version="1">MSKRRWKRLIAWAVLIALVWFALDWLAGWWYRRGPAVRVDATPAQIERGRYLVAAADCAACHTADGGAPFAGGVPLASPFGVIHGTNITPDADTGIGRYSADDFFHAITRGEARDGHQLYPAMPYVSYKTIARADSDAIYAYLMTRPAVKRENSANGVGFPFNIRTGIHAWNLLFAGAQARPASQGQSPQWKRGEYLVETLGHCGECHSPRGWLGQVDRSKPLAGNDALGRFAAPNLTPQGLAQRGWDRAGLQDYLARGVAAHAVASDEMLKVVNLSTSRLSQDDVGAIATYLLGDAPPAPLAFAGANAGAGASIGADSAPAQSRYFALCAGCHGRDGQGVPHVAPALAGNTGVRDPNPHNLIVAILDGLPEHDLPGLERMQDMPGFAAQLNDQEVAELAQWLRARYGGQNSQVSAGQVKDLRESAGSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDV9</accession>
    <name>A0A0S2DDV9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
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        <property type="gene ID" value="GLE_1449"/>
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    <dbReference type="KEGG" id="lez:GLE_1449"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1429"/>
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        <property type="project" value="UniProtKB-KW"/>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="130" mass="13442" checksum="1DA2739E8FA62886" modified="2016-02-17" version="1">MMVGVALAMATMLLFEAGYGLLHPLPAGANAQDPATMNAHIAHAPLSALLLVLGGWVVGALDGGLVAALISRRHKRIAALTVGVVVALGVVAVTSIYTHPRWMQIAGILLPMLASWLGARIAQRRAAPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE86</accession>
    <name>A0A0S2DE86_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">Chromosome partitioning protein ParB</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">ParB chromosome partitioning protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_07640</name>
        <name evidence="2" type="ORF">GLE_1453</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946786.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1453"/>
    <dbReference type="EnsemblBacteria" id="ALN56810">
        <property type="protein sequence ID" value="ALN56810"/>
        <property type="gene ID" value="GLE_1453"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1453"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1433"/>
    <dbReference type="OMA" id="ESDCLVM"/>
    <dbReference type="OrthoDB" id="1238527at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB/Sulfiredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011111">
        <property type="entry name" value="Plasmid_RepB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02195">
        <property type="entry name" value="ParBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07506">
        <property type="entry name" value="RepB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00470">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ParB" evidence="1">
        <location>
            <begin position="10"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="294" mass="33134" checksum="176DE82C06122205" modified="2016-02-17" version="1">MTKTVHDEVLSIPIREIYVLNPRTRNKRIQQEMIENIRLVGLKRPISVARKAKPDGVYRYDLICGQGRMEAFRALGQAEIPAFVLNASQEDCLVMSLVENIARRNHTPLELMREIARLRERGYSDTDIASRIGVVPSWISTVGGLLASGEERLVAAVESGVLPLTMAAVIARSDEAGVRRVLTEAYENGFRGRKLTALRRLIEAREKPHRAHSGPASRNVTKKKPLTLAQARRLFAQEAEKHRIVIQRAEFANERVVFLVQAFKQLVKDGDFIGLLKRQGIESMPAQLSRKLQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEA8</accession>
    <name>A0A0S2DEA8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_1527</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946851.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1527"/>
    <dbReference type="EnsemblBacteria" id="ALN56884">
        <property type="protein sequence ID" value="ALN56884"/>
        <property type="gene ID" value="GLE_1527"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1527"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1509"/>
    <dbReference type="OMA" id="GIYVATN"/>
    <dbReference type="OrthoDB" id="537440at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594890" evidence="2">
        <location>
            <begin position="24"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="526"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="563"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="603"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="637"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="3">
        <location>
            <begin position="64"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="663" mass="71284" checksum="541BA172C4192A27" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEH7</accession>
    <name>A0A0S2DEH7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1690</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946981.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1690"/>
    <dbReference type="EnsemblBacteria" id="ALN57046">
        <property type="protein sequence ID" value="ALN57046"/>
        <property type="gene ID" value="GLE_1690"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1690"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1668"/>
    <dbReference type="OMA" id="CYAHSTA"/>
    <dbReference type="OrthoDB" id="1505479at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="267" mass="29638" checksum="1C16A4FE9F23CFD9" modified="2016-02-17" version="1">MVTRLNLQGRTAWLKSYGGGSRRLRLRALELTARRLGVPSLRPPPHRVGADARQTEQRRLQELAAVDVRVPSILGEGDTYLLLSDIGETLSARLRRSSPQEAYRLVTEAARALAQVHARGGYIGQPLARNLTVDEHGRIGFIDFEEDPAEVMSVQQAQIRDWLIFAAGTSRYFRDPDRELSAIIAESLRGGAEEVRRGLGDAADRLGFVQSLTRWLGRRARGLGGAVQALRRAAWVWALCAVLIGLGVDFAPDRDFDSIRQMAEFID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEH8</accession>
    <name>A0A0S2DEH8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1557</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946875.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56914">
        <property type="protein sequence ID" value="ALN56914"/>
        <property type="gene ID" value="GLE_1557"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1557"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1538"/>
    <dbReference type="OrthoDB" id="2092377at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="114" mass="12852" checksum="DF4AEA84FA669362" modified="2016-02-17" version="1">MSWRRPNYRWQMRAPTRFPLVKSLVLAFFTVLVLAPATAWVMSLPMWAMDTLGYLLASSAQPRMRWFGAAMLLAGVPSLAVVGWRAWRDRDLDAGVMAGVATVAWLVLITMVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEU4</accession>
    <name>A0A0S2DEU4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1474</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56831">
        <property type="protein sequence ID" value="ALN56831"/>
        <property type="gene ID" value="GLE_1474"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1474"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1455"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="46" mass="4495" checksum="4388413D5E9F114E" modified="2016-02-17" version="1">MAAARAFCACRQSPARGGQGSAASFHIDLLAGYRCAHLGASGGSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEU8</accession>
    <name>A0A0S2DEU8_LYSEN</name>
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        <recommendedName>
            <fullName evidence="7">Endolytic murein transglycosylase</fullName>
            <ecNumber evidence="7">4.2.2.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Peptidoglycan polymerization terminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mltG</name>
        <name evidence="9" type="ORF">GLE_1696</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the transglycosylase MltG family.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.-" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1696"/>
    <dbReference type="EnsemblBacteria" id="ALN57052">
        <property type="protein sequence ID" value="ALN57052"/>
        <property type="gene ID" value="GLE_1696"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1696"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1674"/>
    <dbReference type="OMA" id="IAMPGKA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008932">
        <property type="term" value="F:lytic endotransglycosylase activity"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08010">
        <property type="entry name" value="MltG_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02065">
        <property type="entry name" value="MltG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003770">
        <property type="entry name" value="MLTG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30518">
        <property type="entry name" value="PTHR30518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02618">
        <property type="entry name" value="YceG"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TIGR00247"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 7" id="KW-1003">Cell membrane</keyword>
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    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="350"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="7">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN57052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="386" mass="41189" checksum="D0AA69CF542C636F" modified="2016-02-17" version="1">MAAKEKKGKRGCGCLIVIVLLLAALAVGGGWAWQRYLGFADAPLRGLAPDQSLLVERGDSLPTVVRKLRASGVEVGEELEWRLLAKQLGAAGRLQVGEYSLAPGTSPRALLVAMRDGKVVSHRFVIVDGWNVRDLRTALARADKLKQQAAQLDDAALMKALGKGGQHPEGRFLPETYFYTGGDSDLDVLKRAAAAMDKALAASWSGRDKDSVLKTPYELLTMASIVEKETGVPAERAQIAGLFERRLKLGMRLETDPTVIYGIGSAYDGNIRKRDLQTDTPYNTYTRAGLPPTPIAMPGLAALKAAANPAPGDALFFVAAGDGSGRSLFAATYAQHQANVRLYLQRYRQNQGRGQPEEGKAVLEEAAETSPASAAPAAQPAPGASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEX1</accession>
    <name>A0A0S2DEX1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_08250</name>
        <name evidence="1" type="ORF">GLE_1585</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946898.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56942">
        <property type="protein sequence ID" value="ALN56942"/>
        <property type="gene ID" value="GLE_1585"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1585"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1565"/>
    <dbReference type="OrthoDB" id="1998386at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="59" mass="6964" checksum="71E082CDE28F10F9" modified="2016-02-17" version="1">MNPQWKHLVVELTYKLFEAPMRERIQEELDRQGAQGWELVAVEHDPGVLGTRLYFKRPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF27</accession>
    <name>A0A0S2DF27_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">VWA domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">von Willebrand factor, type A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_12550</name>
        <name evidence="4" type="ORF">FE772_08120</name>
        <name evidence="2" type="ORF">GLE_1554</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000031">
        <property type="protein sequence ID" value="OPD63545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946872.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1554"/>
    <dbReference type="EnsemblBacteria" id="ALN56911">
        <property type="protein sequence ID" value="ALN56911"/>
        <property type="gene ID" value="GLE_1554"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63545">
        <property type="protein sequence ID" value="OPD63545"/>
        <property type="gene ID" value="BV903_12550"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1554"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1535"/>
    <dbReference type="OMA" id="AYYRPWV"/>
    <dbReference type="OrthoDB" id="1369887at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Tellurite-R_TerY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF020634">
        <property type="entry name" value="TerY_vWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="1">
        <location>
            <begin position="20"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="226" mass="24372" checksum="7C7BA2184C5A8866" modified="2016-02-17" version="1">MNETAIPDVALVDNTEQRTPLVLVLDCSGSMTGPPMQQLNEGLKLLEDELKSDVIAAKRVRVLVVRYGGFDQAEPAGDWCDAMDFTAPVLEAAGTTPTGRAIDLALSEIENEKQRFKAAGVAYTRPWLFLMSDGAPTDAWEASAQRARDAETANKVAIFPIAVGQGDERIMSQFSSKGPGGVKRLQGLQFRELFLWLSASMQVVSQSRPGGAAQLPSTDTWSSVPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF82</accession>
    <name>A0A0S2DF82_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1951</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57302">
        <property type="protein sequence ID" value="ALN57302"/>
        <property type="gene ID" value="GLE_1951"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1951"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1916"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="39" mass="4105" checksum="06D217E4155540AA" modified="2016-02-17" version="1">MAEGGPAVASGLRWAGRFARQDARLCGSSVCRGRHTGRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFC7</accession>
    <name>A0A0S2DFC7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Histidine ammonia-lyase</fullName>
            <ecNumber evidence="1">4.3.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hutH</name>
        <name evidence="1" type="ORF">GLE_1893</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.3.1.3" evidence="1"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1893"/>
    <dbReference type="EnsemblBacteria" id="ALN57244">
        <property type="protein sequence ID" value="ALN57244"/>
        <property type="gene ID" value="GLE_1893"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1893"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1861"/>
    <dbReference type="OMA" id="MLTRCNS"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004397">
        <property type="term" value="F:histidine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00332">
        <property type="entry name" value="PAL-HAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001106">
        <property type="entry name" value="Aromatic_Lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022313">
        <property type="entry name" value="Phe/His_NH3-lyase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10362">
        <property type="entry name" value="PTHR10362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00221">
        <property type="entry name" value="Lyase_aromatic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00488">
        <property type="entry name" value="PAL_HISTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="632" mass="67841" checksum="3F27631F89010C77" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFM4</accession>
    <name>A0A0S2DFM4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1990"/>
    <dbReference type="EnsemblBacteria" id="ALN57340">
        <property type="protein sequence ID" value="ALN57340"/>
        <property type="gene ID" value="GLE_1990"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1990"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1957"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="54" mass="5585" checksum="E9535D75A6C9215F" modified="2016-02-17" version="1">MAGTRRQERAGLTANQYAQGDIEGLSDYGTRRLVASTVLTESNGGDLAITNGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFU2</accession>
    <name>A0A0S2DFU2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1981</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947186.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
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        <property type="protein sequence ID" value="ALN57331"/>
        <property type="gene ID" value="GLE_1981"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="2180598at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="199" mass="21935" checksum="0FC3BC9D43FBAD0D" modified="2016-02-17" version="1">MVSMHHRRGRGDGSGRAWLAFGVGLALWAGSGAAAAADAGTAFKQAIDSLAAGAYWSKPFVENTLSARLVPDWENEYTLAYKAESGRFAGLRIKEVELRCSKRRARDCLLSIDLAEPGPPNMAFVRKFWPQAVPTPASPHSRFSHEYWTIERGPERISVSNQYDAPRITRVTIAHETELPQIPMDSPPAPPLPRVPDSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-06-17" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG34</accession>
    <name>A0A0S2DG34_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1937</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57288">
        <property type="protein sequence ID" value="ALN57288"/>
        <property type="gene ID" value="GLE_1937"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1937"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1902"/>
    <dbReference type="OMA" id="MQVVFRT"/>
    <dbReference type="OrthoDB" id="2074271at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="142" mass="16568" checksum="6F11D00F47E61A8A" modified="2016-02-17" version="1">MDGYRFTTDLFRIEPGEDEDINPRRYGRQFAQWLNAQLERRGYPVEPVIEEDWGRCLMCAREPFALWVGCGNEVDYDTARPGDPPPPAERVVWQCFAMAEIPWWKRWFTDVDAAPALERLNAVLHEILSAEPRIRLLSDDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG68</accession>
    <name>A0A0S2DG68_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">NADH-quinone oxidoreductase subunit F</fullName>
            <ecNumber evidence="13">7.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">nuoF</name>
        <name evidence="16" type="ORF">FE772_10920</name>
        <name evidence="15" type="ORF">GLE_2164</name>
    </gene>
    <organism evidence="15 17">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="15 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">C3</strain>
        </source>
    </reference>
    <reference evidence="16 18" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 13">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 13">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the complex I 51 kDa subunit family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="13"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947330.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2164"/>
    <dbReference type="EnsemblBacteria" id="ALN57514">
        <property type="protein sequence ID" value="ALN57514"/>
        <property type="gene ID" value="GLE_2164"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2164"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2127"/>
    <dbReference type="OMA" id="CREGTDW"/>
    <dbReference type="OrthoDB" id="688908at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001949">
        <property type="entry name" value="NADH-UbQ_OxRdtase_51kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011537">
        <property type="entry name" value="NADH-UbQ_OxRdtase_suF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011538">
        <property type="entry name" value="Nuo51_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037225">
        <property type="entry name" value="Nuo51_FMN-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019575">
        <property type="entry name" value="Nuop51_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037207">
        <property type="entry name" value="Nuop51_4Fe4S-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019554">
        <property type="entry name" value="Soluble_ligand-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01512">
        <property type="entry name" value="Complex1_51K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10589">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10531">
        <property type="entry name" value="SLBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00928">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140490">
        <property type="entry name" value="SSF140490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142019">
        <property type="entry name" value="SSF142019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01959">
        <property type="entry name" value="nuoF_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00644">
        <property type="entry name" value="COMPLEX1_51K_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00645">
        <property type="entry name" value="COMPLEX1_51K_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 13" id="KW-0288">FMN</keyword>
    <keyword evidence="10 13" id="KW-0408">Iron</keyword>
    <keyword evidence="11 13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 13" id="KW-0520">NAD</keyword>
    <keyword evidence="16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-0874">Quinone</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="NADH_4Fe-4S" evidence="14">
        <location>
            <begin position="348"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU364066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ALN57514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QCW26107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="456" mass="49522" checksum="C1D75F895656365B" modified="2016-02-17" version="1">MAHGHHDYSKGYGPVGPAPQEHQVVYTTLHYDTPWSYENYLKTGGYSALRKILSEKTPPDEIINAVKASGLRGRGGAGFPTGLKWSFMPKGSGTQKYILCNSDESEPGTAKDRDILRFNPHSVVEGMAIACYATGSTVAYNYLRGEFHHEPFEHFEQALKEAYENGWLGKNVLGSGVDIDIYGALGAGAYICGEETALMESLEGKKGQPRFKPPFPANFGLFGKPTTINNTETYASVPAILRNGAEWFAGLGKPNNGGPKIFSVSGHVANPGNFEIRLGTPFSELLQLAGGIRGGRKLKAVIPGGSSMKVLPAATIMECTMDYDSLQKAGSGLGSGAVIVMDETTCMVRACQRIARFYFKESCGQCTPCREGTGWMYRMLTRIAEKQATLEDLQMLRAAAGQIEGHTICAFGEAAAWPVQGFLHHFWDEFEYAIVNKRFLVDDQAAGTVVEKKVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG78</accession>
    <name>A0A0S2DG78_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-lactamase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Serine hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_10585</name>
        <name evidence="4" type="ORF">GLE_2093</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947272.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2093"/>
    <dbReference type="EnsemblBacteria" id="ALN57443">
        <property type="protein sequence ID" value="ALN57443"/>
        <property type="gene ID" value="GLE_2093"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2093"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2057"/>
    <dbReference type="OMA" id="YRDPWYG"/>
    <dbReference type="OrthoDB" id="537440at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021860">
        <property type="entry name" value="Peptidase_S12_Pab87-rel_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11954">
        <property type="entry name" value="DUF3471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726646" evidence="1">
        <location>
            <begin position="24"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="53"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3471" evidence="3">
        <location>
            <begin position="439"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="555" mass="60660" checksum="9550F03F155A612E" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGQ6</accession>
    <name>A0A0S2DGQ6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SURF1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_2373</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SURF1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947490.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2373"/>
    <dbReference type="EnsemblBacteria" id="ALN57722">
        <property type="protein sequence ID" value="ALN57722"/>
        <property type="gene ID" value="GLE_2373"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2373"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2334"/>
    <dbReference type="OMA" id="WYSRDVA"/>
    <dbReference type="OrthoDB" id="1908280at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd06662">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002994">
        <property type="entry name" value="Surf1/Shy1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045214">
        <property type="entry name" value="Surf1/Surf4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427">
        <property type="entry name" value="PTHR23427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02104">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50895">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="254" mass="27595" checksum="9A91BF6EE0E5FA1E" modified="2016-02-17" version="1">MATSVKAPRSSFVLGLIGAVFLALFAGLIALGAWQVQRLGWKRDLIQRVESRVHAEPGDPPAPAQWPGVSAASDEYRHVRLRGRWLPGADTRVQAVTDLGPGFWLLSPLRTDAGYTVLVNRGYVPDARAAQSAPPPPGEAVVTGLLRLSEPGGGFLRDNQPGQDRWFSRDVAAIAAARKLDGAVAPYFVDAERAAPLPADLRTAPQWPVGGLTVIKFPNNHLQYALTWFALALMVAWAAWRVWREQARRRAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGY8</accession>
    <name>A0A0S2DGY8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA-binding response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Regulatory protein virG</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">virG</name>
        <name evidence="7" type="ORF">BV903_00165</name>
        <name evidence="8" type="ORF">FE772_13025</name>
        <name evidence="6" type="ORF">GLE_2594</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">C3</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000001">
        <property type="protein sequence ID" value="OPD65964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947663.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2594"/>
    <dbReference type="EnsemblBacteria" id="ALN57942">
        <property type="protein sequence ID" value="ALN57942"/>
        <property type="gene ID" value="GLE_2594"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65964">
        <property type="protein sequence ID" value="OPD65964"/>
        <property type="gene ID" value="BV903_00165"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2594"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2553"/>
    <dbReference type="OMA" id="NIHGEGF"/>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="11"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="141"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="141"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD65964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW26448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="245" mass="27791" checksum="72AD638CB9FF398E" modified="2016-02-17" version="1">MLLPEQSQRPKVLVVEDDQALAHVIMGHIRTQGMDAYAATDSAEMSESMRQRSHDIVLLDLMLRQENGLDLLRALRRDSDVPVIIMTGHRRDEIDRVVGLELGADDYMPKPFGLHELTARVRAVLRRHSASLMAGVQAAKRAIYRWNDWQFDRAARALTSPEGESVVLTKGEHALLCAFIDAPGRPLSRDHLLRTTRIHDDVFDRSIDVQILRLRRKLERDPVNPQVIVTQRGHGYVFAPAVECI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH41</accession>
    <name>A0A0S2DH41_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PA2169 family four-helix-bundle protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_02345</name>
        <name evidence="4" type="ORF">FE772_12075</name>
        <name evidence="2" type="ORF">GLE_2413</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000004">
        <property type="protein sequence ID" value="OPD65620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947522.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2413"/>
    <dbReference type="EnsemblBacteria" id="ALN57762">
        <property type="protein sequence ID" value="ALN57762"/>
        <property type="gene ID" value="GLE_2413"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65620">
        <property type="protein sequence ID" value="OPD65620"/>
        <property type="gene ID" value="BV903_02345"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2413"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2375"/>
    <dbReference type="OMA" id="YEHAHDE"/>
    <dbReference type="OrthoDB" id="1769096at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011971">
        <property type="entry name" value="CHP02284"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019052">
        <property type="entry name" value="DUF2383"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09537">
        <property type="entry name" value="DUF2383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02284">
        <property type="entry name" value="TIGR02284"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2383" evidence="1">
        <location>
            <begin position="7"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD65620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="148" mass="16163" checksum="E85B8AF819A076BE" modified="2016-02-17" version="1">MTDKKTEHSLNDLIQIARDGEHFYAEAAKKVGDTELAGTFLRMSTAKGAIVSQLSAEVAAGGGKPAESGTFVGTMQEVYGRVRAALGDTRYGYVAELEESEDRLLKAFNEVQGDPNVAPSARAAVERLMPQVRESHREMSQRKHAMKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH60</accession>
    <name>A0A0S2DH60_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947400.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57599">
        <property type="protein sequence ID" value="ALN57599"/>
        <property type="gene ID" value="GLE_2250"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2250"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2215"/>
    <dbReference type="OrthoDB" id="669543at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="365" mass="40587" checksum="CEDB656AE3ADAB70" modified="2016-02-17" version="1">MQAIILGQGNPYLKNPYLAKLSKVLDSAQVPYEFWIWSRDKQARDLPKVRVLLSFGSWGGGAVNALGYALWVLWLSVRVFAQPRAGVYFCSRLDAALPCALVSTVRRCRYVFLDRDKLSKSYAWPAPVKRVIEGLERFVGRRAALHVVPGDSRTQGNDSDNVRVVRNTPHTDTIARARQLAAALPPRDGRLRVLVSGLISPERGAKMMREAIDACAGKIDFVAAGRLLGPDAQRLADGLGERYRGIVSNEEALAMLLDSDVVLAFYDPALEINRLAEPNKWFDCAALEIPFFTNPGLFTSAPFEQRHACFLADYGDGAQLARELLRIDADRSRLEARRAGLRQLRYEAWDTAMARVIAECAELAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-06-17" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHK9</accession>
    <name>A0A0S2DHK9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2645</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57993">
        <property type="protein sequence ID" value="ALN57993"/>
        <property type="gene ID" value="GLE_2645"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2645"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2604"/>
    <dbReference type="OMA" id="WDIAGCL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="393" mass="42856" checksum="6180D5D845CDC403" modified="2016-02-17" version="1">MSAPSAQGHAHSPQAQLVAAADRTLAQHPNFGDSQRILAKVYARYRFGTELFAQRLPQAAALLQQVEAMPDADVRRIFFDPLVRLAAEDAFSELESGQLASPHRLEALLPQAIAALPAGLCESHMLQRWGLQSQEQHWMWSIVGSDDPFAAQLQAAFDRIFADNPANRGLLLNPDAGAQKKVQDSIALLSMLLPNSGPAALRHVGAIALLEAQLEGGIVLSAAGGDLTPSTVFVSLDQLGNPWDIAGCLLHEGLHMKLFDAARSVSLAKEPDATIQVPWRNVRWSIVRAIFAYHVYVHLSLFKAAALVADPRCFELYGDPLAYVSRAHAMSVVNNDTAHQYGRSIDRARYLGEMLEGEWSHLLSPGGFELIHWLRSALAPVDEAMFADAREAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHR1</accession>
    <name>A0A0S2DHR1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ClpV1 family type VI secretion ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">clpV</name>
        <name evidence="8" type="ORF">GLE_2579</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947651.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2579"/>
    <dbReference type="EnsemblBacteria" id="ALN57928">
        <property type="protein sequence ID" value="ALN57928"/>
        <property type="gene ID" value="GLE_2579"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2579"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2538"/>
    <dbReference type="OMA" id="PDMSREF"/>
    <dbReference type="OrthoDB" id="44062at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017729">
        <property type="entry name" value="ATPase_T6SS_ClpV1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03345">
        <property type="entry name" value="VI_ClpV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clp R" evidence="7">
        <location>
            <begin position="10"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN57928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="918" mass="99517" checksum="1F806C6A0BA1E3B8" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHT2</accession>
    <name>A0A0S2DHT2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">LacI family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LacI family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_13110</name>
        <name evidence="5" type="ORF">GLE_2612</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947677.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2612"/>
    <dbReference type="EnsemblBacteria" id="ALN57960">
        <property type="protein sequence ID" value="ALN57960"/>
        <property type="gene ID" value="GLE_2612"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2612"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2572"/>
    <dbReference type="OMA" id="FFMELIS"/>
    <dbReference type="OrthoDB" id="664909at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="2"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW26464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="336" mass="35828" checksum="0EEBBF4B75D2449D" modified="2016-02-17" version="1">MATIYDIAKHVGVSAGTVSRALSRPDKVLPATRQRIEEAAAALGYVPNTVARTLKTQRSGKILVTVPDIANPFFAQILQGAEDAAQAADYAVLLGDTQNRPDREERYAQMLPRNEADGLIVLGHRLPPTAQEIVKRLGATAPVVNGCEFDPALGIPSVHIDNAAASRAAMEHLYGLGHERIAVIGGPPDNPLHRQRLEGVEAAARTRGRLRLLKIAPGDFSIESGYAAAKKLLEQGQGAAPTAAFCFSDQMALGVLAACRDLGLRVPEDFSIVGFDDLASSRYLTPPLTTISQPMREIGVRAVNLLLAIIEAVDVPHQQTLDFSLMLRGSTAALAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI01</accession>
    <name>A0A0S2DI01_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase</fullName>
            <ecNumber evidence="9">1.3.99.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLE_2692</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.3.99.-" evidence="9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2692"/>
    <dbReference type="EnsemblBacteria" id="ALN58040">
        <property type="protein sequence ID" value="ALN58040"/>
        <property type="gene ID" value="GLE_2692"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2692"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2651"/>
    <dbReference type="OMA" id="RDVKLNQ"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="112"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="220"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN58040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="376" mass="40623" checksum="39901A5960A4C299" modified="2016-02-17" version="1">MIQDVARRIAQEKIAPSAEHHDQTGEFPLENIRTLGENGLMGIEVPAEYGGAGMDPVAYVLAMVEIAAGDAAHSTIVSVNNSLFCNGILKFGSEEQKQLYVRAIAEGREIGAFALTEPQSGSDATAMRCKAVKQADGSFVINGKKSWITSGPVAKYIVLFAMTDPDKGARGITAFMIDTAKPGFHRGKTEPKLGIRASATCEIEFEDYVAQPADVLGEEGHGFKIAMGVLDAGRIGIASQAIGIARAAYERTLEYVKERKAFGAPIGTFQMTQAKIADMKCKLDAALLLTLRAAWQKGQTEKNGGRFSNEAAIAKLTASEAAMWITHQAVQIHGGMGYSKEMPLERYFRDAKITEIYEGTSEIQRLVIARNETGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-06-17" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI06</accession>
    <name>A0A0S2DI06_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2735</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58083">
        <property type="protein sequence ID" value="ALN58083"/>
        <property type="gene ID" value="GLE_2735"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2735"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2693"/>
    <dbReference type="OMA" id="CMLRRDW"/>
    <dbReference type="OrthoDB" id="1511450at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="245" mass="25256" checksum="004817C2B196AD15" modified="2016-02-17" version="1">MEIARLRERLERDHWPRLQMSLIVLLTGAVGFLASFALLQAGLHSMALRYPLAACAAYAAFLLLLWTWARTRGRAFDQLDAPDFGGGSGGGPSGAGCNGGGGHSGGGGASSSFDAPASLPLPRSASTGGDGDSGFSLLDGADDFGWVLIAIAIALGAVLAAGWVVWIAPGLMAELLLDVALAGGLYRRLRRIESQHWLSTALRRTALPFLLLALLAAAAGFAGSRYAPGADSIGDVLAAQRADRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI22</accession>
    <name>A0A0S2DI22_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_13745</name>
        <name evidence="1" type="ORF">GLE_2751</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947784.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58099">
        <property type="protein sequence ID" value="ALN58099"/>
        <property type="gene ID" value="GLE_2751"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2751"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2708"/>
    <dbReference type="OrthoDB" id="1638316at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="151" mass="16893" checksum="FDAE3E69A40483E0" modified="2016-02-17" version="1">MPDHPELPALIAVDHDDYHAEHVGRLADGRQFFLTTPFAGALQGAAGNEFVALYLFDAAGALLEARIDEFGPRAGMDREARNRVYEQRLAELGEIEFDRIEIAPFSLTRFGVEFGLIPNWPEDEGEPLSISLQPGDYMAFFEPWDSGDYDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI73</accession>
    <name>A0A0S2DI73_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Hydrolase</fullName>
            <ecNumber evidence="2">3.5.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_13965</name>
        <name evidence="2" type="ORF">GLE_2796</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947820.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2796"/>
    <dbReference type="EnsemblBacteria" id="ALN58144">
        <property type="protein sequence ID" value="ALN58144"/>
        <property type="gene ID" value="GLE_2796"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2796"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2752"/>
    <dbReference type="OMA" id="KIHRFGF"/>
    <dbReference type="OrthoDB" id="1650683at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="265" mass="29787" checksum="04F6C05899B97808" modified="2016-02-17" version="1">MNDLRITLIQGATRWHDPAANREYYGELIGQAQGITDLVLLPETFTSGFSNEAIGNAETMDGPTVAWIREQAARLNAAVCGSVQLRTDEGVFNRLLFATPDGALRTYDKRHLFRYAKEHERYAAGRERLSVEWKGWRICPLVCYDLRFPVFSRNRYDVERPGAPDYDLLLYVANWPSARAYPWKTLLRARAIENLCYVAGLNRVGTDGNGLHYAGDSAVIDFLGHPVSECTDEEVVVTTTLQAAELAAHRARFPAMLDGDRFELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI82</accession>
    <name>A0A0S2DI82_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_14205</name>
        <name evidence="1" type="ORF">GLE_2847</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947857.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58195">
        <property type="protein sequence ID" value="ALN58195"/>
        <property type="gene ID" value="GLE_2847"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2847"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2806"/>
    <dbReference type="OrthoDB" id="1915130at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="124" mass="13613" checksum="8DA9D64A1AB8D178" modified="2016-02-17" version="1">MQNSFDIAIGRCQSVTGKEVVVELDTAMVSRLVPGHPWHRSGTSKLKLAIELCSAQRPPQPGGETFLNRDAILKNPSGRFDLLGDGQFTAVRLKALAANTEPELLEPAPKLNWAERRVSRSHRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIJ3</accession>
    <name>A0A0S2DIJ3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Lipolytic enzyme, G-D-S-L family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_14265</name>
        <name evidence="4" type="ORF">GLE_2857</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2857"/>
    <dbReference type="EnsemblBacteria" id="ALN58205">
        <property type="protein sequence ID" value="ALN58205"/>
        <property type="gene ID" value="GLE_2857"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2857"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2819"/>
    <dbReference type="OMA" id="WTAILKP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242214" evidence="2">
        <location>
            <begin position="20"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH_hydro" evidence="3">
        <location>
            <begin position="77"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="241" mass="26245" checksum="03DF702DC053A126" modified="2016-02-17" version="1">MRRFLLPLLLVLLAACATAPQPGGTAASEAPAPAGTAQRDSAEWEPAIRAFEAQDARVRRMPGSVVFVGSSSIRMWTTLADDFPGVALINRGYGGSRVYDSVHYAERIVVPYQPRAVVFYAGDNDLNDGRTPRQVRDDFAAFVRKVQAAAPKARIAFVSIKPSPSRAALLPQVREANALVRDFARGVRNVDYLDVYAPMLDAGGAPREELFLADRLHMNRAGYEIWIGVVGPWLAKLPSPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIL3</accession>
    <name>A0A0S2DIL3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2941</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58289">
        <property type="protein sequence ID" value="ALN58289"/>
        <property type="gene ID" value="GLE_2941"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2941"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2903"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="57" mass="5643" checksum="DDDA8931C34C4242" modified="2016-02-17" version="1">MGGASAPKLFDQFASGLIASEPKASGLKALPQKPSLASPIAIVGGASAPTLFDQFAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIN1</accession>
    <name>A0A0S2DIN1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 9">GTPase Der</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GTP-binding protein EngA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">engA</name>
        <name evidence="7 13" type="synonym">der</name>
        <name evidence="12" type="ORF">BV903_02655</name>
        <name evidence="13" type="ORF">FE772_14495</name>
        <name evidence="11" type="ORF">GLE_2905</name>
    </gene>
    <organism evidence="11 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">C3</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">B25</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 9">GTPase that plays an essential role in the late steps of ribosome biogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Associates with the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8 9">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000005">
        <property type="protein sequence ID" value="OPD65437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947897.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000005.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2905"/>
    <dbReference type="EnsemblBacteria" id="ALN58253">
        <property type="protein sequence ID" value="ALN58253"/>
        <property type="gene ID" value="GLE_2905"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65437">
        <property type="protein sequence ID" value="OPD65437"/>
        <property type="gene ID" value="BV903_02655"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2905"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2867"/>
    <dbReference type="OMA" id="KFRFLEY"/>
    <dbReference type="OrthoDB" id="263682at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00195">
        <property type="entry name" value="GTPase_Der"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031166">
        <property type="entry name" value="G_ENGA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016484">
        <property type="entry name" value="GTP-bd_EngA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032859">
        <property type="entry name" value="KH_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14714">
        <property type="entry name" value="KH_dom-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006485">
        <property type="entry name" value="GTP-binding_EngA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03594">
        <property type="entry name" value="GTPase_EngA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51712">
        <property type="entry name" value="G_ENGA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 7 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 7" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="EngA-type G" evidence="10">
        <location>
            <begin position="3"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="EngA-type G" evidence="10">
        <location>
            <begin position="179"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="9"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="57"/>
            <end position="61"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="119"/>
            <end position="122"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="185"/>
            <end position="192"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="232"/>
            <end position="236"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="297"/>
            <end position="300"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN58253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OPD65437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW26681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="466" mass="51286" checksum="8D1F363A376B6A92" modified="2016-02-17" version="1">MLPLVALVGRPNVGKSTLFNALTRSRDALVHDEPGVTRDRHYGVCRPEGQRAFAVVDTGGIAGEEQGLAGATARQARAAAEEADLVLFVVDGREGASALDDEILAWLRKTSRPTLLVVNKTDGIDARAAIDDFARYGIRDAIAVSSAHRQGLDELLAEVLARVPEEGATAELDNDPNRIRVAFIGRPNVGKSTLVNRLLGEERMIASDVPGTTRDSVAVDMERDGRLYRLVDTAGVRRKSKVEEAVEKFSIIKTLQAIEQCQVAVVMLDCTEGVTDQDASVLGYALDAGRALVIAVNKWDGQTEYQRQQTENLLKRKLAFVEWAEPVRISAKHGSGLKELFAAIHRAHASATTEIGTSEVTKAMEIAYETNPPPVVRGHVAKLRFAHPAGLNPPTFVVHGTRLRTLSDSYKRYLENFFRKRFKLVGTPVRFVFKEGSNPYEGKKNVLTERQVAKKKRLIRHVKRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIU0</accession>
    <name>A0A0S2DIU0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3111</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3111"/>
    <dbReference type="EnsemblBacteria" id="ALN58458">
        <property type="protein sequence ID" value="ALN58458"/>
        <property type="gene ID" value="GLE_3111"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3111"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3068"/>
    <dbReference type="OMA" id="SASDGYW"/>
    <dbReference type="OrthoDB" id="1827851at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="271" mass="28769" checksum="0472FB8E9E5EE805" modified="2016-02-17" version="1">MGLSPNRPIRKERDCMDRPDVPFRRRAACCAALVLSSAAAAAMAAAAPVAPAAAAAAKPVKAAPAQAAAAPGAVAGVPAAEWTVRWWRWANNAFPDGLAPYRDRDGRLCATGQDEHGPVWFLAGTDGSFAAQRRCRVPAGAHLMVPVINMYFHAPTAGPHAMDCAEVKRAAAVNNDYLASAVVLLDGKPLARPLRLASRCFDPQAARAHPGPDRGGRYRAAADGYWLLLPPLAPGPHRLSVGANYGNPYDSEYGRMQQNFEYQLQVGDPAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIX4</accession>
    <name>A0A0S2DIX4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3121</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948059.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3121"/>
    <dbReference type="EnsemblBacteria" id="ALN58468">
        <property type="protein sequence ID" value="ALN58468"/>
        <property type="gene ID" value="GLE_3121"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3121"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3078"/>
    <dbReference type="OMA" id="GFTPERW"/>
    <dbReference type="OrthoDB" id="1832083at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="293" mass="31894" checksum="0D06018581B51E8A" modified="2016-02-17" version="1">MSQQPILRVLDHTDTALHPAYCEYVARVFSQADFRRWCEWGQWAPGYLAYSLFEDGRVVANASTMRQRLIVDGEEILAFQFGAVGCLPQHRGRGLARRAMQAALAGCGDAPALLFANDSVLDFYPRFGFAPAPQSLFEAAHALAPAPQRAPQRDLADADARERFLAVAARAAPLGRRFASRDYGRTATWYAANGYAAPLFEIDADTWVFAHEQDGALTIEDVFAVAPSHAALAAALPRLIVGPVETLRFGFDPCALWPQAGPAGADDEAGLFLRGIDPARLGPHSRFPLLART</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIZ3</accession>
    <name>A0A0S2DIZ3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">3-methyl-2-oxobutanoate hydroxymethyltransferase</fullName>
            <ecNumber evidence="5">2.1.2.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ketopantoate hydroxymethyltransferase</fullName>
            <shortName evidence="5">KPHMT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">panB</name>
        <name evidence="10" type="ORF">BV903_09395</name>
        <name evidence="11" type="ORF">FE772_15780</name>
        <name evidence="9" type="ORF">GLE_3176</name>
    </gene>
    <organism evidence="9 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">C3</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O = (6S)-5,6,7,8-tetrahydrofolate + 2-dehydropantoate</text>
            <dbReference type="Rhea" id="RHEA:11824"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5 8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 5">Homodecamer; pentamer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the PanB family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.11" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000020">
        <property type="protein sequence ID" value="OPD64247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948098.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000020.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3176"/>
    <dbReference type="EnsemblBacteria" id="ALN58522">
        <property type="protein sequence ID" value="ALN58522"/>
        <property type="gene ID" value="GLE_3176"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64247">
        <property type="protein sequence ID" value="OPD64247"/>
        <property type="gene ID" value="BV903_09395"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3176"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3131"/>
    <dbReference type="OMA" id="VLVWTDM"/>
    <dbReference type="OrthoDB" id="916845at2"/>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00003"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003864">
        <property type="term" value="F:3-methyl-2-oxobutanoate hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06557">
        <property type="entry name" value="KPHMT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00156">
        <property type="entry name" value="PanB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003700">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20881">
        <property type="entry name" value="PTHR20881"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02548">
        <property type="entry name" value="Pantoate_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000388">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00222">
        <property type="entry name" value="panB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3 5" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Alpha-ketoisovalerate binding" evidence="5 7">
        <location>
            <begin position="59"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5 6">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7 8">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>3-methyl-2-oxobutanoate</name>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000388-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000388-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000388-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN58522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD64247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW26884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="279" mass="29044" checksum="7CBC216E7E02DF36" modified="2016-02-17" version="1">MYTSAPTDATPSEKRKAWTVPMLADAKRDGRKLVMLTAYDASFARTMDAVGTDLVLVGDSLGMVVQGHNSTLPVSAADMAYHTACVARGLSKALLIADLPFASDATAERALDASTALLRAGAAMVKIEGAGHKLDIIRFLVEREIPVCAHLGLTPQSVLRLGGYKLQGRDDATAAKLRADARAVAEAGAALLVLECVPTGLAQAITAEIAIPTIGIGAGPHCDGQVLVLHDLLGVNSGHRRPKFVKDFLAEGGSVAGAFAAYGEAVRSGRFPDASHSYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJA0</accession>
    <name>A0A0S2DJA0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_16195</name>
        <name evidence="2" type="ORF">GLE_3272</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948168.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58618">
        <property type="protein sequence ID" value="ALN58618"/>
        <property type="gene ID" value="GLE_3272"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3272"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3225"/>
    <dbReference type="OrthoDB" id="2191450at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242160" evidence="1">
        <location>
            <begin position="33"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="78" mass="8341" checksum="D5ACFA8962B26987" modified="2016-02-17" version="1">MSIAELRRAPAARRLAGLAFCFGLAFSLSAFAGLTPEQCALCWDDCNARAQLCREEGGTPGECGRERLRCVNACGCRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJI5</accession>
    <name>A0A0S2DJI5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Acetyltransferase, GNAT family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_16450</name>
        <name evidence="2" type="ORF">GLE_3326</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948211.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58672">
        <property type="protein sequence ID" value="ALN58672"/>
        <property type="gene ID" value="GLE_3326"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3326"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3276"/>
    <dbReference type="OMA" id="NHVEMLF"/>
    <dbReference type="OrthoDB" id="1390922at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="148" mass="16741" checksum="12961280F6EBEDA2" modified="2016-02-17" version="1">MPIRERRRDDNPRLLALWERSVRATHDFLAEADIDELRPQVRDVYLDAVDIWVFEDADGLAGFVGLADAQVEMLFLEPQRRGQGIGTRLLDHARGLRGALTVDVNEHNPQAHGFYRRYGFVDTGRSPLDGQGRPFPLIHMALPRDAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJL6</accession>
    <name>A0A0S2DJL6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutathione S-transferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Glutathione S-transferase III</fullName>
            <ecNumber evidence="4">2.5.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_15545</name>
        <name evidence="4" type="ORF">GLE_3125</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948061.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3125"/>
    <dbReference type="EnsemblBacteria" id="ALN58472">
        <property type="protein sequence ID" value="ALN58472"/>
        <property type="gene ID" value="GLE_3125"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3125"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3081"/>
    <dbReference type="OMA" id="ADVQMSF"/>
    <dbReference type="OrthoDB" id="1383885at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="91"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="225" mass="25279" checksum="23F0A5C85BAF2835" modified="2016-02-17" version="1">MIKVHHLNNSRSQRVLWLLEELALPYEVVRYQRDPKTMLAPPELRAIHPLGKSPLVELDGQVLAESAAIIETLCERYDRGHALSPPPQPLDGEERRRYRYWMHYAEGSAMPPLLLSLVFSRIKSAPMPFFVKPVARGIADKAMSSFVGPQLALHLGYIESELGKHEWFAGERFTAADIQMSFPVEAAAARAGAGRPRMQAFVERIHARPAYQRALEKGGPYSLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJN7</accession>
    <name>A0A0S2DJN7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Metalloprotease PmbA</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">PmbA protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pmbA</name>
        <name evidence="6" type="ORF">FE772_16775</name>
        <name evidence="5" type="ORF">GLE_3402</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase U62 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948268.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3402"/>
    <dbReference type="EnsemblBacteria" id="ALN58748">
        <property type="protein sequence ID" value="ALN58748"/>
        <property type="gene ID" value="GLE_3402"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3402"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3351"/>
    <dbReference type="OMA" id="LYRKSTF"/>
    <dbReference type="OrthoDB" id="958356at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045569">
        <property type="entry name" value="Metalloprtase-TldD/E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045570">
        <property type="entry name" value="Metalloprtase-TldD/E_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002510">
        <property type="entry name" value="Metalloprtase-TldD/E_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035068">
        <property type="entry name" value="TldD/PmbA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036059">
        <property type="entry name" value="TldD/PmbA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01523">
        <property type="entry name" value="PmbA_TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19289">
        <property type="entry name" value="PmbA_TldD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19290">
        <property type="entry name" value="PmbA_TldD_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111283">
        <property type="entry name" value="SSF111283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PmbA_TldD" evidence="2">
        <location>
            <begin position="42"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_M" evidence="4">
        <location>
            <begin position="134"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_C" evidence="3">
        <location>
            <begin position="247"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW27048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="456" mass="48331" checksum="F993488255DC2AA0" modified="2016-02-17" version="1">MNAQALTAAAHTFADPEQRLDALAELSQRLLAAARARGATQAEVSCSEDAGLSVNVRMGEVETVESTRDRGIGVTVYFGQRKGSASTADLREDSLESTVEQACAIARYTEDDPAAGLADAALMAREERDFDTWHPWLIDADRAIELALACESAGRGFDARIENSDGTSIGTGASIGVYANSHGFIGRERSTQHSLSCALIAGRGDQMQRDGWYTLGLAPEDMESAAAVGRKAAERTVSRLAPRQLATGDYPVLFAAESARSLIGHLISAVSGGNLYRRTSFLVDSVGQTLFPEWFSIRETPFLMRGLRSTAYDAEGVATRESSLVEGGVLQRYVLGSYSARKLGLSTTGNAGGVHNLHVAANAGDFDALVKQMGRGLLVTELMGQGVNGVTGDYSRGAAGFWVEGGEIQYPVDGITIAGNLRRMFAGIEAVGSDIDPRSHIRTGSILLGKMTVAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK38</accession>
    <name>A0A0S2DK38_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid/peptide transporter (Peptide:H+ symporter)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_3638</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3638"/>
    <dbReference type="EnsemblBacteria" id="ALN58982">
        <property type="protein sequence ID" value="ALN58982"/>
        <property type="gene ID" value="GLE_3638"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3638"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3582"/>
    <dbReference type="OMA" id="PFAALWV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904680">
        <property type="term" value="F:peptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006857">
        <property type="term" value="P:oligopeptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17346">
        <property type="entry name" value="MFS_DtpA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005279">
        <property type="entry name" value="Dipep/tripep_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018456">
        <property type="entry name" value="PTR2_symporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="PTHR11654"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00924">
        <property type="entry name" value="yjdL_sub1_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01022">
        <property type="entry name" value="PTR2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01023">
        <property type="entry name" value="PTR2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
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        <location>
            <begin position="93"/>
            <end position="110"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <begin position="130"/>
            <end position="150"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
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            <begin position="197"/>
            <end position="216"/>
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            <begin position="244"/>
            <end position="264"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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            <begin position="276"/>
            <end position="298"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="327"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="584"/>
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        <source>
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        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
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        <source>
            <dbReference type="RuleBase" id="RU003755"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="592" mass="63601" checksum="FADC3ABEF459A48B" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK97</accession>
    <name>A0A0S2DK97_LYSEN</name>
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        <submittedName>
            <fullName evidence="6">DUF4105 domain-containing protein</fullName>
        </submittedName>
        <submittedName>
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        </submittedName>
    </protein>
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        <name evidence="6" type="ORF">FE772_17860</name>
        <name evidence="5" type="ORF">GLE_3630</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ALN58974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW27218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3630"/>
    <dbReference type="EnsemblBacteria" id="ALN58974">
        <property type="protein sequence ID" value="ALN58974"/>
        <property type="gene ID" value="GLE_3630"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3630"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3574"/>
    <dbReference type="OMA" id="YRYNFFY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025178">
        <property type="entry name" value="DUF4105"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
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        <location>
            <begin position="29"/>
            <end position="460"/>
        </location>
    </feature>
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            <end position="451"/>
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            <end position="227"/>
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    </feature>
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            <end position="87"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF13387"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN58974.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW27218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="460" mass="50702" checksum="043496EF930C837D" modified="2016-02-17" version="1">MTAFPRFVRLYALLALLALLSLLPLAQAAPPPLAATAAEAASASARASNTDADADAGSANADTAGMPGIPAATPPATPPPSARDATDSTVPRIGVVTMQPGQEFWSRFGHDALVVYDRASEKAISYNFGYFDPSDPDFVQRFVRNDMRYRLVALPFDQDMAQYRYEGRKVELQWLDLNDAQARALAESLRVNALPENAFYRYQYFDDNCSIRVRDALDRALGGNLRRQIEGRSHGNTLRSEALRLSKPEPWMWFVLDVLMGPETDKPVPVWAESYVPGRLAAALREVKNDEGRPLVESERTLLPSHIPAEPEATPLPWWPWALAGIGLGVALAWIGRRSPRVLAVAALPLWAALGVVGALLVYAWLGTGHTYIHANRNLLLFDPLCLLLLFGGVRALRGRDPGPVFGWLSLAVALAAVASLFVYWLPVYPQRNAHWIALWLPVHLGLWFGFRRATGLARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKG8</accession>
    <name>A0A0S2DKG8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein translocase subunit SecE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 8" type="primary">secE</name>
        <name evidence="9" type="ORF">BV903_21105</name>
        <name evidence="10" type="ORF">FE772_18715</name>
        <name evidence="8" type="ORF">GLE_3803</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the SecE/SEC61-gamma family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000067">
        <property type="protein sequence ID" value="OPD61940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948567.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000067.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3803"/>
    <dbReference type="EnsemblBacteria" id="ALN59147">
        <property type="protein sequence ID" value="ALN59147"/>
        <property type="gene ID" value="GLE_3803"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61940">
        <property type="protein sequence ID" value="OPD61940"/>
        <property type="gene ID" value="BV903_21105"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3803"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3747"/>
    <dbReference type="OMA" id="MNSKIEH"/>
    <dbReference type="OrthoDB" id="1974284at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00422">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005807">
        <property type="entry name" value="SecE_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038379">
        <property type="entry name" value="SecE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001901">
        <property type="entry name" value="Translocase_SecE/Sec61-g"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33910">
        <property type="entry name" value="PTHR33910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00584">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01650">
        <property type="entry name" value="SECETRNLCASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00964">
        <property type="entry name" value="secE_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD61940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="127" mass="13741" checksum="1085548DC880FFD3" modified="2016-02-17" version="1">MNSKAEQHKSSGGNAGDLVKYVLALALAAGGVFAYIWFENWSGPLRAAVVVAGLVAGAAVFMLSAKGAQTREFLSESRFELRKVVWPTRDEALKTTWVVMVAVLILSLILSGFDWVIQAAVKFLLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKH1</accession>
    <name>A0A0S2DKH1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">DNA-directed RNA polymerase subunit beta</fullName>
            <shortName evidence="6">RNAP subunit beta</shortName>
            <ecNumber evidence="6 8">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">RNA polymerase subunit beta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Transcriptase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 15" type="primary">rpoB</name>
        <name evidence="16" type="ORF">BV903_21075</name>
        <name evidence="15" type="ORF">GLE_3797</name>
    </gene>
    <organism evidence="15 17">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="15 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">C3</strain>
        </source>
    </reference>
    <reference evidence="16 18" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">B25</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6 8">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="6 8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000067">
        <property type="protein sequence ID" value="OPD61934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948561.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000067.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3797"/>
    <dbReference type="EnsemblBacteria" id="ALN59141">
        <property type="protein sequence ID" value="ALN59141"/>
        <property type="gene ID" value="GLE_3797"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61934">
        <property type="protein sequence ID" value="OPD61934"/>
        <property type="gene ID" value="BV903_21075"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3797"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3741"/>
    <dbReference type="OMA" id="FMTWEGY"/>
    <dbReference type="OrthoDB" id="9601at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01321">
        <property type="entry name" value="RNApol_bact_RpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019462">
        <property type="entry name" value="DNA-dir_RNA_pol_bsu_external_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010243">
        <property type="entry name" value="RNA_pol_bsu_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="PTHR20856"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10385">
        <property type="entry name" value="RNA_pol_Rpb2_45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02013">
        <property type="entry name" value="rpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3 6 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA_pol_Rpb2_1" evidence="12">
        <location>
            <begin position="32"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_2" evidence="11">
        <location>
            <begin position="161"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_2" evidence="11">
        <location>
            <begin position="365"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_2" evidence="11">
        <location>
            <begin position="453"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_3" evidence="13">
        <location>
            <begin position="544"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_45" evidence="14">
        <location>
            <begin position="622"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_6" evidence="9">
        <location>
            <begin position="750"/>
            <end position="1309"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_7" evidence="10">
        <location>
            <begin position="1311"/>
            <end position="1385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF10385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ALN59141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OPD61934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="1387" mass="155089" checksum="AF197E4F6A86CC17" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKJ5</accession>
    <name>A0A0S2DKJ5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dihydrodipicolinate synthase family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Dihydrodipicolinate synthetase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_07480</name>
        <name evidence="4" type="ORF">FE772_18155</name>
        <name evidence="2" type="ORF">GLE_3683</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DapA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000014">
        <property type="protein sequence ID" value="OPD64597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948470.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000014.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3683"/>
    <dbReference type="EnsemblBacteria" id="ALN59027">
        <property type="protein sequence ID" value="ALN59027"/>
        <property type="gene ID" value="GLE_3683"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64597">
        <property type="protein sequence ID" value="OPD64597"/>
        <property type="gene ID" value="BV903_07480"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3683"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3627"/>
    <dbReference type="OMA" id="WCTAAPC"/>
    <dbReference type="OrthoDB" id="1438588at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="PTHR12128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="303" mass="32451" checksum="559BF39EF99F967A" modified="2016-02-17" version="1">MHNIDLHGIVAYPITPFREEDGGVDADTLVRLIDQLIDAGVHAIAPLGSTGESAYLSESEWRHVVETSVIRVARRVPVIVGISELTTAAAARRATFAEEAGADAIMVLPTSYWKLGEEEVFQHYARIAAATRLPIMAYNNPATSGIDMSPELMIRMVREIDNVCMIKESSGDIQRMHRIHELSGGTVPFFNGSNPLALEAFAAGATGWCTAAACLIPEQTLSLYAAVRSGNLAAARQTFYRQLPLLQFILKGGLPKTVKAGLRLQGLDVGAPRHPVLPLDEAGCRALATILGQVASGEARSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKL0</accession>
    <name>A0A0S2DKL0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA ligase (ATP)</fullName>
            <ecNumber evidence="2">6.5.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">NHEJ DNA polymerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">ligD</name>
        <name evidence="16" type="ORF">GLE_3698</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="6.5.1.1" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948481.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3698"/>
    <dbReference type="EnsemblBacteria" id="ALN59042">
        <property type="protein sequence ID" value="ALN59042"/>
        <property type="gene ID" value="GLE_3698"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3698"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3642"/>
    <dbReference type="OMA" id="QEFVICG"/>
    <dbReference type="OrthoDB" id="2061599at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04862">
        <property type="entry name" value="PaeLigD_Pol_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012309">
        <property type="entry name" value="DNA_ligase_ATP-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014146">
        <property type="entry name" value="LigD_ligase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014144">
        <property type="entry name" value="LigD_PE_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014145">
        <property type="entry name" value="LigD_pol_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014143">
        <property type="entry name" value="NHEJ_ligase_prk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033651">
        <property type="entry name" value="PaeLigD_Pol-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04679">
        <property type="entry name" value="DNA_ligase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13298">
        <property type="entry name" value="LigD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02777">
        <property type="entry name" value="LigD_PE_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02778">
        <property type="entry name" value="ligD_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02779">
        <property type="entry name" value="NHEJ_ligase_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02776">
        <property type="entry name" value="NHEJ_ligase_prk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="8" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 16" id="KW-0436">Ligase</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="12" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_LIGASE_A3" evidence="15">
        <location>
            <begin position="315"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="518"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="536"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ALN59042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="878" mass="96631" checksum="E048BD23C4E9397A" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKM9</accession>
    <name>A0A0S2DKM9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF3106 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_19010</name>
        <name evidence="3" type="ORF">GLE_3868</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948607.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3868"/>
    <dbReference type="EnsemblBacteria" id="ALN59211">
        <property type="protein sequence ID" value="ALN59211"/>
        <property type="gene ID" value="GLE_3868"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3868"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3807"/>
    <dbReference type="OMA" id="KLHSRMT"/>
    <dbReference type="OrthoDB" id="1980311at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021455">
        <property type="entry name" value="DUF3106"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11304">
        <property type="entry name" value="DUF3106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242326" evidence="2">
        <location>
            <begin position="24"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="167" mass="19307" checksum="0EF89903C18633A9" modified="2016-02-17" version="1">MRRPFFRRAEPLLALALAVAALAAPTLAAAQTAPAGAALPSWDQLSQAQREQLIAPMRDRWNTQPEERQRMLDRARRWQQMTPDERREARNGMKRWEGLNPEERGQMRALYGKMRGLDENGKRALMEKWRTMTPDQRRAWAESNPPPPKQRGDHHFPPPPPPPPPRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKN8</accession>
    <name>A0A0S2DKN8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate epimerase</fullName>
            <ecNumber evidence="1">5.1.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">UDP-MurNAc-L-Ala-L-Glu epimerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">murL</name>
        <name evidence="3" type="ORF">FE772_18375</name>
        <name evidence="2" type="ORF">GLE_3731</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Cell wall formation. Catalyzes epimerization of the terminal L-glutamate in UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate = AMP + diphosphate + H(+) + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</text>
            <dbReference type="Rhea" id="RHEA:58812"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
            <dbReference type="ChEBI" id="CHEBI:142725"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="5.1.1.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MurL family.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.23" evidence="1"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948506.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3731"/>
    <dbReference type="EnsemblBacteria" id="ALN59075">
        <property type="protein sequence ID" value="ALN59075"/>
        <property type="gene ID" value="GLE_3731"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3731"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3676"/>
    <dbReference type="OMA" id="CRFVFLA"/>
    <dbReference type="OrthoDB" id="306410at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016855">
        <property type="term" value="F:racemase and epimerase activity, acting on amino acids and derivatives"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02209">
        <property type="entry name" value="MurL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043689">
        <property type="entry name" value="MurL"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="1" id="KW-0133">Cell shape</keyword>
    <keyword evidence="1" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
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    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="1" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="452" mass="49571" checksum="26502E15173E3E63" modified="2016-02-17" version="1">MSEQFQRDAVRAFRFVRCGLNAATGVAELVYAFDDGPELVETVTVPGAPFALDGARAQAVERMLRLLHLIAGVSYYKAAVPEQIRIDSYAIDANTAALLELIYVNGLGEFAYRNGLNLHGKITFPVAAAADPAAPALGLSEHALVAIGGGKDSLVSIEALRALDVEQTVTWIGGSQLIAACAARTGLDTLNLGRALAPQLFEYNRQGAYNGHIPVTVVNSAIMALAALLRGVDQVVFSNERSASYGSMIEGTGEVNHQWSKGWDCERAFGEYLQAHVAADLRYYSLLRPLSELAVARQFARGDRYDAHFSSCNRNFHILGERPASRWCGVCPKCHFVFLALAPFMTKPRLVSIFGRNLLDDPAQTDGFDALLEYRNHKPFECVGEGRESRAAMAALAERAEWREDALVERFAREIRPQLAGEELRIEPLLALEGEHRVPPALWERLRAYLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKP4</accession>
    <name>A0A0S2DKP4_LYSEN</name>
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        <submittedName>
            <fullName evidence="10">ABC transporter, ATP-binding protein</fullName>
        </submittedName>
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    <gene>
        <name evidence="10" type="ORF">GLE_3673</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
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    <dbReference type="STRING" id="69.GLE_3673"/>
    <dbReference type="EnsemblBacteria" id="ALN59017">
        <property type="protein sequence ID" value="ALN59017"/>
        <property type="gene ID" value="GLE_3673"/>
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    <dbReference type="KEGG" id="lez:GLE_3673"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3615"/>
    <dbReference type="OMA" id="VMVPQDG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
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        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
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    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="17"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="329"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="363"/>
            <end position="370"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="579" mass="62450" checksum="9933D3C3A9645E46" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKZ5</accession>
    <name>A0A0S2DKZ5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Protease 1</fullName>
            <ecNumber evidence="7">3.4.21.50</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_3843</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.21.50" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948593.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3843"/>
    <dbReference type="EnsemblBacteria" id="ALN59186">
        <property type="protein sequence ID" value="ALN59186"/>
        <property type="gene ID" value="GLE_3843"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3843"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3783"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
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        <property type="entry name" value="P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01483">
        <property type="entry name" value="P_proprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51829">
        <property type="entry name" value="P_HOMO_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595776" evidence="4">
        <location>
            <begin position="21"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="5">
        <location>
            <begin position="479"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="P/Homo B" evidence="6">
        <location>
            <begin position="559"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="499"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="678" mass="71740" checksum="6007F33F09565D40" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL29</accession>
    <name>A0A0S2DL29_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter, ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_3932</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3932"/>
    <dbReference type="EnsemblBacteria" id="ALN59274">
        <property type="protein sequence ID" value="ALN59274"/>
        <property type="gene ID" value="GLE_3932"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3932"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3869"/>
    <dbReference type="OMA" id="MRDEIMD"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="10"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="47"/>
            <end position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="244" mass="26588" checksum="4922C5E5E810B9AD" modified="2016-02-17" version="1">MAATPAAAVIETRALGKVYSPGSEAEVIALHGVDLRIARGEFVAIMGPSGSGKSTLMNLIGCLDTPTSGVYLCDGVDVATLDKEERAILRRDKIGFVFQGFNLLPRMNALENVAMPMGYANVRHDERAQRAQEALEAVGLGQRAGHRPSELSGGQQQRVAIARALINRPPILLADEPTGALDTRTGEEILALFKSLQARDHTVVLITHDPDVAAHADRIFVMRDGELHEQEREPEQQQKRDLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLF0</accession>
    <name>A0A0S2DLF0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Efflux ABC transporter, permease protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="12">FtsX-like permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BV903_14705</name>
        <name evidence="12" type="ORF">FE772_19290</name>
        <name evidence="10" type="ORF">GLE_3931</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">C3</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000038">
        <property type="protein sequence ID" value="OPD63140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948655.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000038.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3931"/>
    <dbReference type="EnsemblBacteria" id="ALN59273">
        <property type="protein sequence ID" value="ALN59273"/>
        <property type="gene ID" value="GLE_3931"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63140">
        <property type="protein sequence ID" value="OPD63140"/>
        <property type="gene ID" value="BV903_14705"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3931"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3868"/>
    <dbReference type="OMA" id="MGSNMIT"/>
    <dbReference type="OrthoDB" id="768211at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="288"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="9">
        <location>
            <begin position="21"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="318"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OPD63140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW27462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="412" mass="43410" checksum="D10C141E2B19C661" modified="2016-02-17" version="1">MNFFEVLRTAVFALRGNWLRSALTSLGVIIGIAAVIVMVSVGQGTQSEIDKLVSGLGSNRLDISSGGGGRGTGGVRLSSSSFFTLTEADAEAIRNEVPEVQYVAASLRGGTQAVYAENNWSTQWQGVQPDFFDINGWTIAAGSNFEARDYGSGAKSVILGETVRRSLFGDEDAIGQTVRLGRVPYTVIGTLNPKGQGGFGQDQDDVVLVPLETGRRRMLGAMGLPNGAVMQIAVGVGRAEDVSYAQEQIEGLLRQRHKIQPGSDDDFSVRNIAEVVATRTQTTRLMSLLLGAVATISLIVGGIGIMNIMLVSVTERIREIGLRMAVGAGPGDIQRQFLAEAMLISLIGGALGIAIGIVGTLLVGRIGALPVALNGQVIALAAGFSIATGLFFGYYPARKASQLDPIEALRQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLK0</accession>
    <name>A0A0S2DLK0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">PKD domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Peptidase, families S8 and S53/PKD domain/proprotein convertase P-domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FE772_18945</name>
        <name evidence="9" type="ORF">GLE_3854</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3854"/>
    <dbReference type="EnsemblBacteria" id="ALN59197">
        <property type="protein sequence ID" value="ALN59197"/>
        <property type="gene ID" value="GLE_3854"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3854"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3794"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04077">
        <property type="entry name" value="Peptidases_S8_PCSK9_ProteinaseK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002884">
        <property type="entry name" value="P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034193">
        <property type="entry name" value="PCSK9_ProteinaseK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01483">
        <property type="entry name" value="P_proprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51829">
        <property type="entry name" value="P_HOMO_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242337" evidence="6">
        <location>
            <begin position="24"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="7">
        <location>
            <begin position="405"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="P/Homo B" evidence="8">
        <location>
            <begin position="484"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN59197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="605" mass="61906" checksum="812118A312F6198C" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLY0</accession>
    <name>A0A0S2DLY0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4148</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948824.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4148"/>
    <dbReference type="EnsemblBacteria" id="ALN59490">
        <property type="protein sequence ID" value="ALN59490"/>
        <property type="gene ID" value="GLE_4148"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4148"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4090"/>
    <dbReference type="OMA" id="SACICAA"/>
    <dbReference type="OrthoDB" id="1585347at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="407" mass="40749" checksum="75959DAFB729C7F6" modified="2016-02-17" version="1">MRRIAPTSPRSRRRRIASACICAALALGLGGCGAVRTIAGINTVHLEQARVDSMQIDLASGAATVCPRERVQMHVVVGAQLPSQPAPLLYETWRGSNGTRRNGMLDFRNFAFNSEQGRFDELGWFAPNPDVLATVDSGFAIGANLIHPSAQFARTAHYPPSYDCIAAVGAPGGGGAQGRDGGYGDSGHDGHDGGHGGRGGYGRNGGDGEPGGGGYDGPHLRAYATYIATGRYPKLLAVRVEGDLQDLVLAPAMRAFTVIASGGRGGAGGDGGSGGAGGDGGRGSDDKDRPGHGGDGGDGGDGGYGAPGGHGGDGGEIELIYDRRFPELAELLRFDVSGGIGGDSGSAGSGGSGGDGGRGGLGQGRDGRSGDYGGSGPVGPSGRPGLARMRAGDVSAQFRGLPGVKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM15</accession>
    <name>A0A0S2DM15_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA polymerase III subunit chi</fullName>
            <ecNumber evidence="1">2.7.7.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">holC</name>
        <name evidence="2" type="ORF">BV903_04230</name>
        <name evidence="3" type="ORF">FE772_20575</name>
        <name evidence="1" type="ORF">GLE_4196</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.7" evidence="1"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000008">
        <property type="protein sequence ID" value="OPD65135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948862.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000008.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4196"/>
    <dbReference type="EnsemblBacteria" id="ALN59538">
        <property type="protein sequence ID" value="ALN59538"/>
        <property type="gene ID" value="GLE_4196"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65135">
        <property type="protein sequence ID" value="OPD65135"/>
        <property type="gene ID" value="BV903_04230"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4196"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4138"/>
    <dbReference type="OMA" id="WQFEPSA"/>
    <dbReference type="OrthoDB" id="1575254at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007459">
        <property type="entry name" value="DNA_pol3_chi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036768">
        <property type="entry name" value="PolIII_chi_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38767">
        <property type="entry name" value="PTHR38767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04364">
        <property type="entry name" value="DNA_pol3_chi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102400">
        <property type="entry name" value="SSF102400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD65135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="141" mass="15918" checksum="B6D2E1E3F51B0278" modified="2016-02-17" version="1">MPRADFYLIQSPRFKEEPMRLVCELARKAHAASLPTLILARSAEQAEQLDDMLWDMGEDAYIPHQIAGMDEDEDEADVLIAAPDHDPALRALVINLRDAAVADGFERVLEVVPADDGARGPLRERWKQYQARGLQLNKHDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM73</accession>
    <name>A0A0S2DM73_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4328</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59669">
        <property type="protein sequence ID" value="ALN59669"/>
        <property type="gene ID" value="GLE_4328"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4328"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4267"/>
    <dbReference type="OMA" id="GAGPIWP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="107" mass="12361" checksum="67C8700A971BE2B2" modified="2016-02-17" version="1">MSRFVELNLALILFLPWFAILGALFWLYPRRPRNPARKLFDAVSLAISVCAFVLAVHWAHLHAGREYGAMWPQILATSLGYGVFLAVLTVAFALRWRWLRGVKDYRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM95</accession>
    <name>A0A0S2DM95_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycolate oxidase iron-sulfur subunit</fullName>
            <ecNumber evidence="4">1.1.99.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">glcF</name>
        <name evidence="6" type="ORF">GLE_4262</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(R)-lactate + A = AH2 + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:15089"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>A + glycolate = AH2 + glyoxylate</text>
            <dbReference type="Rhea" id="RHEA:21264"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29805"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="EC" id="1.1.99.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="4">Binds 2 [4Fe-4S] clusters.</text>
    </comment>
    <dbReference type="EC" id="1.1.99.14" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4262"/>
    <dbReference type="EnsemblBacteria" id="ALN59603">
        <property type="protein sequence ID" value="ALN59603"/>
        <property type="gene ID" value="GLE_4262"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4262"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4201"/>
    <dbReference type="OMA" id="VYQDACH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004017">
        <property type="entry name" value="Cys_rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012257">
        <property type="entry name" value="Glc_ox_4Fe-4S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02754">
        <property type="entry name" value="CCG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000139">
        <property type="entry name" value="Glc_ox_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2 4" id="KW-0408">Iron</keyword>
    <keyword evidence="3 4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="366" mass="38288" checksum="10C0062D355137D1" modified="2016-02-17" version="1">MQCGLCLPACPTYGHDRLEAESPRGRIALARAWALDTIPATAASDTHLDHCLGCRSCEAVCPAGVEYGRLLVAARSRQRERRPAGWRQRLVERLAARPRALAAGLAVYRAAYPLLPAAARPLPRPPGRVRALPRRAGASTARVSLFVGCVAGAYEAPLRAALARLCGGLGIELDIAADQGCCGALHEHAGDTAAAAALAARNRAAFAGRGTVLSLASGCHDSLRRALGDGAHATDALAFVAERAGALRWRRTPQRVALHLPCTQRNVVKSVPALRRLLAAVPGLEVIELDAGFGCCGASGTQMLTEPARAAEYRAPLLAQFERSGATRLLSANVGCRLHLANATAAPVLHPLEFLAECLDDGSAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DME4</accession>
    <name>A0A0S2DME4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase type 11</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948900.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4244"/>
    <dbReference type="EnsemblBacteria" id="ALN59585">
        <property type="protein sequence ID" value="ALN59585"/>
        <property type="gene ID" value="GLE_4244"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4244"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4185"/>
    <dbReference type="OMA" id="SHTFYHD"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025282">
        <property type="entry name" value="DUF4214"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13946">
        <property type="entry name" value="DUF4214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DUF4214" evidence="1">
        <location>
            <begin position="85"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="466" mass="52211" checksum="0E991083F6D41477" modified="2016-02-17" version="1">MNQALDPLDVDAVMQAVSARLREAIPVESDGVAGADGAVERMRSQLDRAFARRGGDGEELQHWRSVTHSIPVKREYVLSELLGPADASFVEMAYRVVLRREPDPDGFNYFLHELRSGHTTKVEVLGALRWSEEGMAKQVHIDGLMLPYKLQQWKRKPVFGRALSWLHGVARLGSLFDRQYTIEATQAREAHELGRHVNLLMDELKQVRGQQAGLLRNVARMMPMFERMHAAELERERFQPTMDKLYADFEDEFRGSRELVRARIEPYLDWVREAGAGGADAPVVDIGCGRGEWLELLAEHGLQASGIDLNRDFVDSCAGTGLKVVAGDAVDVLREMPEGSLGAVTSMHLVEHLPFERVVALIDAALRALRPGGLLLLETPNPENIMVGSHYFYMDPTHLNPLPPAMLRWVVENRGFAESRIERLSAHRPLNAPPLLPPEVPGSKSLNDMLWSMHIAPDYAIVARRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMN3</accession>
    <name>A0A0S2DMN3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4453</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4453"/>
    <dbReference type="EnsemblBacteria" id="ALN59794">
        <property type="protein sequence ID" value="ALN59794"/>
        <property type="gene ID" value="GLE_4453"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4453"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4390"/>
    <dbReference type="OMA" id="HTGMHAT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="169" mass="17792" checksum="0BAD743820AE3C4B" modified="2016-02-17" version="1">MSAGDAPHGEQARAAGPDGGEPRQGPLPIDEAVREIGEAGREGLSAALDTGRALRGLLIADLALARSALGRALMWVAVAIVFGASTWLLLMAALIALLQGALGWSWLASMSAAAGLSLVVTAIGGWQALRYFEHTRLSATRRQLRRMGLGHDDDDDDDRGTGARRQEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMP7</accession>
    <name>A0A0S2DMP7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxygen-independent coproporphyrinogen III oxidase 1</fullName>
            <ecNumber evidence="2">1.3.99.22</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4439</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.3.99.22" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949055.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4439"/>
    <dbReference type="EnsemblBacteria" id="ALN59780">
        <property type="protein sequence ID" value="ALN59780"/>
        <property type="gene ID" value="GLE_4439"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4439"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4376"/>
    <dbReference type="OMA" id="CERLCWF"/>
    <dbReference type="OrthoDB" id="1130951at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034505">
        <property type="entry name" value="Coproporphyrinogen-III_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010723">
        <property type="entry name" value="HemN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932">
        <property type="entry name" value="PTHR13932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06969">
        <property type="entry name" value="HemN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Radical SAM core" evidence="1">
        <location>
            <begin position="51"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="449" mass="50916" checksum="537FBFE4DEE27924" modified="2016-02-17" version="1">MEPLKISLVGDAPPPLAEAPADYRGETPNRNGFVVAWPPQRYWKSASETDLTSEKPLHLYFHIPYCLQRCRYCFYKIEILSDSSHAQRERYVSALCREIELVADAHRLRGRAVRSIYFGGGTPSVIPPEQLARIKRTIEQCFRLEDPEFVFEIEPITLNNRMIDGLTNLGVNRISFGIQSFDDRVVALTGRHDTDEKNSRAIERALQTGAVVNVDLLAGLEGETMDSWQHSINRAIALGVHAVTVYKMELYSNAHYMSEIRQGKLSLPSEDEELAFARWGLDRLRDNGYAPSTYFTFTREGKYPQHHIISRWRGEDLYGFGASAFGTVAGHARQNVSEIDVYLERVESGRIPTQRVLELSSADHMMRDLVMGLKTTVIDLDEYRRRHGLRLDHALADEIAHLSREGLVAVEDGRLRLTDEGIVYGDYSGRYLGAGLRRVFTGDTKPLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMS6</accession>
    <name>A0A0S2DMS6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_22000</name>
        <name evidence="1" type="ORF">GLE_4504</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949105.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59845">
        <property type="protein sequence ID" value="ALN59845"/>
        <property type="gene ID" value="GLE_4504"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4504"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4440"/>
    <dbReference type="OMA" id="NQVEITQ"/>
    <dbReference type="OrthoDB" id="1365410at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="726" mass="79639" checksum="12E5D9BD82D962E3" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMW9</accession>
    <name>A0A0S2DMW9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rhodanese domain protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Sulfurtransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_22320</name>
        <name evidence="3" type="ORF">GLE_4573</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949153.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4573"/>
    <dbReference type="EnsemblBacteria" id="ALN59914">
        <property type="protein sequence ID" value="ALN59914"/>
        <property type="gene ID" value="GLE_4573"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4573"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4509"/>
    <dbReference type="OMA" id="PDSCVRQ"/>
    <dbReference type="OrthoDB" id="1928533at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01444">
        <property type="entry name" value="GlpE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023695">
        <property type="entry name" value="Thiosulf_sulfurTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="221"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="314" mass="33859" checksum="E8D003B765EF5A77" modified="2016-02-17" version="1">MDALLHLIENYGLLVVFVCVLLDQGGLPVPAYPPIVVASAVAVGHQPNLWLALPPVLLTATLAALLADSAWYFGGRRIGARLLRLMCRLSLSPDSCVLTTRSLYARWGAPSLVVAKFVPGFAAVATVLAGETGTRARRFAFYDGLGALLWAGAAVALGAVFHRAVNQLLERLDTLGRYGLIALAAMLAAWIGYKLLKRQLFLRELRMARISVAELAQLLAAGSEPTILDVRPHQQRDASGWIPGAIFVATLADESLNGIAPQRREEVIVYCDCPSEASAATLARELRRRGFKRVRPLAGGFEAWRAQGLAVAQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMZ5</accession>
    <name>A0A0S2DMZ5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lipase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Platelet-activating factor acetylhydrolase, plasma/intracellular isoform II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_22465</name>
        <name evidence="5" type="ORF">GLE_4605</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949175.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4605"/>
    <dbReference type="EnsemblBacteria" id="ALN59946">
        <property type="protein sequence ID" value="ALN59946"/>
        <property type="gene ID" value="GLE_4605"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4605"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4540"/>
    <dbReference type="OMA" id="LMISIWY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003847">
        <property type="term" value="F:1-alkyl-2-acetylglycerophosphocholine esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005065">
        <property type="entry name" value="PAF_acetylhydro-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10272">
        <property type="entry name" value="PTHR10272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03403">
        <property type="entry name" value="PAF-AH_p_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242584" evidence="4">
        <location>
            <begin position="40"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW27997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="428" mass="46527" checksum="D22BD4D9816F2599" modified="2016-02-17" version="1">MFRAIRIGLSRFAAAPRRLLAAALLSPALSLLAAAPALAATPQAPAAAPKRFDLPPTTGPYKVGTFTLHIVDRARTDRFVGGPREYMVTVSYPIAPHARGARAPWLEPALVPEWSATAAGYGIAPEAVDWAGARRPAIQGAPLLRNPRGWPVVLFSPGLQYFRELYSSFTDDLASHGYVVASMTHTHEAFYTAFPGGRVVRGQDLVETVESTQMWLDTRVGDSRHLLDALTLSNRGFYPGAGHGRLPPGWRGGLDLSRVGFLGHSYGGTTAAETMFFDRRFDAGLDYDGRLSTTYGPPQDLPYGPTLAARFGLDRPFLLVGAGVHSHLDSHDPSWPQFWASQRGWKREVNVARGEHFTFSDFTAVLPALGDAVPPGFGVAVYGSLPPAQAVAATRYHSRAFFDLHLKGRPTRLFDRGSPAYPEFRPVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN53</accession>
    <name>A0A0S2DN53_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59972">
        <property type="protein sequence ID" value="ALN59972"/>
        <property type="gene ID" value="GLE_4631"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4631"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4567"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="160" mass="16310" checksum="368E42CD143602FF" modified="2016-02-17" version="1">MPISSSPICTSRALXXXXXXXACMRVLRAVARGQAFVAADLRSARCGREDTVLRAHYDRDAGLVRAPADLAAGAAIAPVAPTLLADLRQGDKVALIYRDGAIAISRGGVAARDSKPGAPVRVALADGAVVTAPSSAADPVFVPALPSLPLPSSSRPGETP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN94</accession>
    <name>A0A0S2DN94_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF481 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_03675</name>
        <name evidence="3" type="ORF">FE772_22210</name>
        <name evidence="1" type="ORF">GLE_4550</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000006">
        <property type="protein sequence ID" value="OPD65395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949140.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000006.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59891">
        <property type="protein sequence ID" value="ALN59891"/>
        <property type="gene ID" value="GLE_4550"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65395">
        <property type="protein sequence ID" value="OPD65395"/>
        <property type="gene ID" value="BV903_03675"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4550"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4486"/>
    <dbReference type="OrthoDB" id="1704964at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007433">
        <property type="entry name" value="DUF481"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04338">
        <property type="entry name" value="DUF481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD65395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="237" mass="26011" checksum="71A8438F39C0C60E" modified="2016-02-17" version="1">MLGRLHDRFQTMLGAIGLALLGAPLVTLPNPAFGGDPTLIAIASDPAQMRLYCFSTRCGDEEWRVAMAPKQRLPDIDPAELPPLRPNVFLPGQQRVGIGGVSAPASSRESRAMYSNDHRIGARYGVQAMRDGPTQIGLSFGAGYRLAPLYDDGINRTGAVFRGELNLGQRLTDRARWTQRVQVESGRGDTFVKQSVRLDVDLYPNWKLETDFAIRHDNKGGGGTDSAESSIELIRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNE4</accession>
    <name>A0A0S2DNE4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4727</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949265.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4727"/>
    <dbReference type="EnsemblBacteria" id="ALN60068">
        <property type="protein sequence ID" value="ALN60068"/>
        <property type="gene ID" value="GLE_4727"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4727"/>
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        </location>
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        <location>
            <begin position="19"/>
            <end position="672"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="672" mass="72570" checksum="25E07A4F5D4869E2" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNP9</accession>
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            <fullName evidence="2">Uncharacterized protein</fullName>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
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    <sequence length="148" mass="15977" checksum="03E720FF1053A58F" modified="2016-02-17" version="1">MAQAARRSSSRAWLSRRRNAPLFPSAALRNRTPAMTEISRLDRLIAQLRVHLRKQGGATAARQPRQEGAPAREAGRQSPLQAVQALKAAGVGDEKVLVGRLVEGLLAEEFGDELANSAEFHQTIAVVVSVLGEDAEAWALCRACVEEA</sequence>
</entry>
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            <authorList>
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        </source>
    </evidence>
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        <source>
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</entry>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="38" mass="4072" checksum="A32189297C45F9A2" modified="2016-02-17" version="1">METVASERSRNKRRAGAAPAESERNAGRLPGFAAFLPV</sequence>
</entry>
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        <submittedName>
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        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">BV903_11285</name>
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            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
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    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000026">
        <property type="protein sequence ID" value="OPD63890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057950344.1">
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_5150"/>
    <dbReference type="EnsemblBacteria" id="ALN60491">
        <property type="protein sequence ID" value="ALN60491"/>
        <property type="gene ID" value="GLE_5150"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63890">
        <property type="protein sequence ID" value="OPD63890"/>
        <property type="gene ID" value="BV903_11285"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
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    </dbReference>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="OPD63890.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW28417.1"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="208" mass="22662" checksum="8057D4093CA3AD63" modified="2016-02-17" version="1">MQIRSNSFQHRQRLAAEFAAGQATADGFGFAANRNPHLAWDDVPAGARSFALICIDPDVPTVAEMVGRADVRIPEHQVRGDFIHWVMADIPADVREIAAGSCSDGVVAHGKRDPAGPRGARQGLNDYTGWFASDPAMAGDWYGYDGPFPPPNDLRLHRYFFRLYALDVERLPLAPRFGAGDVFNAMHGHVLAQASIYGTYSLNPAVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP86</accession>
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    <protein>
        <submittedName>
            <fullName evidence="2">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5023</name>
    </gene>
    <organism evidence="2 3">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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    <dbReference type="STRING" id="69.GLE_5023"/>
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        <property type="protein sequence ID" value="ALN60364"/>
        <property type="gene ID" value="GLE_5023"/>
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    <dbReference type="KEGG" id="lez:GLE_5023"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="DUF3526"/>
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    <dbReference type="Pfam" id="PF12040">
        <property type="entry name" value="DUF3526"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="236"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="270"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="297"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="478"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="510" mass="55617" checksum="BF391EC60343BB87" modified="2016-02-17" version="1">MSAQTGHLGALDLPAARTAGFAELLRWELGHVGRSRLLWAVLGLLFAAMLWGAHSGAALHREQDRAIQRSRAADLAWTQQILERARRYAEPADEPVPYWQDPTDVAGFSRYFLRAHAYKPNLPLSPLAVGGSDLMPTRLPVKLETPFGVEPAYDFENPRALGLGRFDLGYVLVYLLPVAAIVLIGLLATFERDHGMLRLIAAQRVGPRAWLGARIAAIFAWLAPAVLLGVAVSLFSAGADLAAAVPELIASAALVVAYLGFWAALGFVVVSAWPGAAGAISLMSAVWAVLAIGLPLLGSGAAARLGDAPAPIAYVDAQRRANDAIAGERDALLARDFRARGDLAGSLDKLGSLDYATRMTFLAPELERRLQPLRDRQEGARSARERLSQWAGYLTPPLGMEQALAQLAGTDAQRHRRFERQAAGYQRQLREWFYPRIQRQISAPTPKPRADSYGRMNFLEFDAIPAYAWHDAPAWSRVAGALPTALWLTLLAAALSAWALRRLRQWPAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPA8</accession>
    <name>A0A0S2DPA8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="13">HemY-like protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="14">Porphyrin biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BV903_18325</name>
        <name evidence="13" type="ORF">GLE_5037</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">C3</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">B25</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in a late step of protoheme IX synthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Porphyrin-containing compound metabolism; protoheme biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000049">
        <property type="protein sequence ID" value="OPD62492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949506.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000049.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5037"/>
    <dbReference type="EnsemblBacteria" id="ALN60378">
        <property type="protein sequence ID" value="ALN60378"/>
        <property type="gene ID" value="GLE_5037"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62492">
        <property type="protein sequence ID" value="OPD62492"/>
        <property type="gene ID" value="BV903_18325"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5037"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4965"/>
    <dbReference type="OMA" id="WGKARDY"/>
    <dbReference type="OrthoDB" id="699592at2"/>
    <dbReference type="UniPathway" id="UPA00252"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042168">
        <property type="term" value="P:heme metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005254">
        <property type="entry name" value="Heme_biosyn_assoc_TPR_pro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010817">
        <property type="entry name" value="HemY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07219">
        <property type="entry name" value="HemY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00540">
        <property type="entry name" value="TPR_hemY_coli"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="HemY_N" evidence="12">
        <location>
            <begin position="29"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN60378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OPD62492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="416" mass="44795" checksum="6D30908152C8BC99" modified="2016-02-17" version="1">MNLFRNLLFWIVLALLGALVAQLLLQDPGRVVITYGGYDYLTNVPKALLMLVGGLIALWLVWKALSLPFVAMRRHRKKQARARLIDGLDALHQGHWTRAEKSLAQAARSRDVAAIAAVGAARAAAARGDAAAQAQHLDAIAADHPVARALAAAEQALAEERAGDALAALDAPAAQPLPPRGLALRAQALAALGRAGEAYGLLGALRQNNAWPSARLGRLEAQWAEAALREAADANVLADLWESLPKPLKNEPAAVAAYAERAAEMRWEEAAAKSLEQALDARWDESLAALYGRLPIGRLDARRAQAERWLAGHPGSPGLLLSLARLARMQGQWPQAEAYLHRALAQGAGSEAWEELGHGFAQAGDESRARLSYLNALRAARGEAPSELPGRDLRQKLFDEAVVEERDEFGMPRLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPM8</accession>
    <name>A0A0S2DPM8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_04640</name>
        <name evidence="5" type="ORF">FE772_25500</name>
        <name evidence="3" type="ORF">GLE_5273</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000009">
        <property type="protein sequence ID" value="OPD65038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949682.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5273"/>
    <dbReference type="EnsemblBacteria" id="ALN60614">
        <property type="protein sequence ID" value="ALN60614"/>
        <property type="gene ID" value="GLE_5273"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65038">
        <property type="protein sequence ID" value="OPD65038"/>
        <property type="gene ID" value="BV903_04640"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5273"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5191"/>
    <dbReference type="OMA" id="RNWKWVV"/>
    <dbReference type="OrthoDB" id="1795990at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014807">
        <property type="entry name" value="Coa1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08695">
        <property type="entry name" value="Coa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="16"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD65038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW28504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="180" mass="18921" checksum="012694093A17C462" modified="2016-02-17" version="1">MNDRPNPGWFGRNWKWFVPTGCLSVLLFAALALAGLIGLGIKGVSGLMSGSEPVRHAMDLAKANPDVRAAFGEPLETGMGFQGSLTTNNDSGEADLSLPIKGPKGSGRIYVKGTREADRWSYRLIEVAIDGSERRIDLLGADAAPDAAPEAASPERSAPDESTPEEESDPEAPAEESAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPP5</accession>
    <name>A0A0S2DPP5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD monooxygenase, PheA/TfdB family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">FAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_23380</name>
        <name evidence="2" type="ORF">GLE_4811</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949331.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4811"/>
    <dbReference type="EnsemblBacteria" id="ALN60152">
        <property type="protein sequence ID" value="ALN60152"/>
        <property type="gene ID" value="GLE_4811"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4811"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4743"/>
    <dbReference type="OMA" id="MYIGYVG"/>
    <dbReference type="OrthoDB" id="867226at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="7"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="492" mass="53994" checksum="CF5BFB3A641B18FC" modified="2016-02-17" version="1">MSREENDLVIAGAGPVGLLCAYLAQRCGLRTAIVDKTAGPLEAGRADALNARTLQLLEIADLFDALYPHGKTCDTSSVWADGAFVSRQSAWWKALDGCFHKHFLMLGQSHLERLLDDRLKALGAPVLRDTAVEQVELGERGCLTRLSDGRTLASRFVIGADGSRSPLREAFGIGFEIRRPQLIWAVIDGVVETDFAKVPEIIVFQAETSDVAWIPREGDLDRFYVRMDTQEFSFEQAVAKINRAMRPHTLRFSEVAWFSRFSVKEAVAERYAVDDRLFLAGDACHIHSVNGGQGLNTGLADAFNLIWKMHLVLRHGAPQRLLASYQDERKPVALGVVETSSQLVHSTKYSSGNTHAQDYVKIVERRAGYITGMGIAYGDAAVDGDVICGKRLLDFMVRRGDALVRVYSLLDYRRFALLLFGDCRAPAELPAFVQTIRIDASESPESPESPYPDGMLLVRPDAHIAAAAPGDGGAAILACLDALMQRETVAMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPP9</accession>
    <name>A0A0S2DPP9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PLP-dependent aminotransferase family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_23710</name>
        <name evidence="3" type="ORF">GLE_4882</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949387.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4882"/>
    <dbReference type="EnsemblBacteria" id="ALN60223">
        <property type="protein sequence ID" value="ALN60223"/>
        <property type="gene ID" value="GLE_4882"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4882"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4813"/>
    <dbReference type="OMA" id="WQSYVET"/>
    <dbReference type="OrthoDB" id="1320028at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="2">
        <location>
            <begin position="32"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="502" mass="54569" checksum="88812CBC1C951BF3" modified="2016-02-17" version="1">MEPVFDAAASAAGDPDGPVFEFPLELPARGHGQLTHELHQQLRAAILDGRLAAGAALPATRRVAAGLGVARNTVVAAYDLLIAEGYLAPRRGAKAVVADVAARRDRRAPRRLSAGPEDPRLNPLWRTPFLRPEPPRDLPERCFRLGIPDHRHFPHEIWRRLSAQTLRAWSRTGFSYPPSEGIAELREAIAQHVAFARAVACGGEDVVVTSGAQQAFDLLARLLVTPGETRVAVEEPGYPPVRAAFAAAGARLLPIPVDEEGLCVDLLPEDARVISVTPSHQSPTGVALSLRRRRALLDFARRRNALVIEDDYDGEFRFGHRPLDALQTLDRDGLVFYIGTFSKSLFPSLRKGFIVAPRWARDALATVKHCADSHSDTITQSVLAAFIRDGHLARHVRRMRAVYAPRREALLAALDAELAPWLQPIPCEAGMHLAARIRDPALAPAILARLPRHMPGAQSIAEYAMSAPAQPAIAFGYGVADVDQIRPATRAFARSLAGIGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPR9</accession>
    <name>A0A0S2DPR9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nipsnap family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5249</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949665.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5249"/>
    <dbReference type="EnsemblBacteria" id="ALN60590">
        <property type="protein sequence ID" value="ALN60590"/>
        <property type="gene ID" value="GLE_5249"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5249"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5168"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012577">
        <property type="entry name" value="NIPSNAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07978">
        <property type="entry name" value="NIPSNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NIPSNAP" evidence="1">
        <location>
            <begin position="174"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="405" mass="45485" checksum="DC14346AD4BAD4A1" modified="2016-02-17" version="1">MNHDGRHDFDFLHGHWQVRNERLRERLAGSDDWEIFHATQTCEPVLGGLGNVDAFLSEWRRDGGEDTFQGMTLRLFDLQRGRWNIWWAGSHDGVLEPPVSGGFADGVGVFEGELEHHGRPVRARFVWSAIGANTAHWHQQFSIDGGASWETNWHMWLRRRDAGGRLPHEDAVIELRRYTLKPGRRDELIELFERELIEPQEAVGMHVIGQFRELDESDRYTWVRGFPGHAARVEALHGFYGGPTWKRHRDAANATMIDSDDVRLLKPARPRSALPAAQRERAPVGASADADGIVCIGVCELDAPAQAGFLERFERDFAPLLEPAGLSLLGVYVSDDTANGFPRLPVREGEPALVWFCGCADAQAPRRLAETPQWRAAVADALRAGLRRAPQLLRLAPTARSELRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPT3</accession>
    <name>A0A0S2DPT3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Glucose/galactose MFS transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="13">Glucose/galactose transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="15">Sugar MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">BV903_11305</name>
        <name evidence="15" type="ORF">FE772_24985</name>
        <name evidence="13" type="ORF">GLE_5156</name>
    </gene>
    <organism evidence="13 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">C3</strain>
        </source>
    </reference>
    <reference evidence="14 17" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">B25</strain>
        </source>
    </reference>
    <reference evidence="15 18" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 18">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Intake of glucose and galactose.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000026">
        <property type="protein sequence ID" value="OPD63883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949595.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5156"/>
    <dbReference type="EnsemblBacteria" id="ALN60497">
        <property type="protein sequence ID" value="ALN60497"/>
        <property type="gene ID" value="GLE_5156"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63883">
        <property type="protein sequence ID" value="OPD63883"/>
        <property type="gene ID" value="BV903_11305"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5156"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5079"/>
    <dbReference type="OMA" id="CFESACF"/>
    <dbReference type="OrthoDB" id="1121832at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005354">
        <property type="term" value="F:galactose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005355">
        <property type="term" value="F:glucose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005964">
        <property type="entry name" value="Glc/Gal_transptr_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01272">
        <property type="entry name" value="gluP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="9 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="81"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="240"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="312"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="336"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
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        <location>
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            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003321"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN60497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OPD63883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW28420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="439" mass="46173" checksum="E6835949A64DFF0E" modified="2016-02-17" version="1">MSVANASAPPRYLMSIGIIGALFFVFGFVTWLNGPLIGFAQLAFDLDEVGAFLVPMAFYLSYFFLALPASSILRFTGMKRGMALGLLVMAIGAAVFGEFTTQRWYPGALGGLFVIGAGLAVLQTAVNPYISILGPIEGAAQRIAVMGICNKIAGILAPIVLGTLVLHGMGDLAEQVKGADPATKEQLLNQFASSIHGPYLLMAGVLAVLAVGVLFSPLPELRGEEVNKSGADNGGAGRGLFGYPHLWLGALCIFVYVGVEVMAGDAIGTYGHSFGLPLDKTKFFTSFTLGGMLLGYIVGLIVIPRFISQERYLSWSAVLGVLLSIGAFATHGYVSVLFVAALGFANAMMWPAIFPLGIRGLGRHTETGSAIMVMGIAGGAVVPQLYAVLKQHFDFQAVFLALMVPCYLYILFFAKVGHKVGQRESGGAGAAARPAVEAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ39</accession>
    <name>A0A0S2DQ39_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_25430</name>
        <name evidence="2" type="ORF">GLE_5256</name>
    </gene>
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        <name type="scientific">Lysobacter enzymogenes</name>
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    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_5256"/>
    <dbReference type="EnsemblBacteria" id="ALN60597">
        <property type="protein sequence ID" value="ALN60597"/>
        <property type="gene ID" value="GLE_5256"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5256"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5175"/>
    <dbReference type="OMA" id="TPIWVWI"/>
    <dbReference type="OrthoDB" id="1666006at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="170" mass="18370" checksum="F547E038E6264E92" modified="2016-02-17" version="1">MNLSHLLQATPTWVFILFAVLLALGLRRLRTGVQSLVRVWAVPAIFIAWGLYGLVVHLGAAPTNLLHWIAGAAVGGVLGLWSLDPAALAFDHQRRLVRQPGSALPLLRNLGIFGAHYVLQVFAATHPQLRDSAMGWDLVVSGFSAGYFVGWAARFLAGQRRAPQTDLASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQF0</accession>
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    <protein>
        <submittedName>
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    </protein>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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    </dbReference>
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        <property type="gene ID" value="GLE_5348"/>
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    </dbReference>
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    </dbReference>
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        </location>
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            <begin position="99"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="448" mass="48413" checksum="6FC431B58CB21899" modified="2016-02-17" version="1">MDKATVGKHPCPECGGDLQWNAAKQALACPYCGTVVPLAQAPQGAGDGSAQIVEHDLEQALARLPPESPGANAPAANATGAQDPDLAAIHATIERLARTPGGAPATASSWSVKASSTDGGGFELKGSQNGHALDLLRSMAATPPEQRGYGAQRREVQCQSCHAISVFVDGKVADRCEFCGSPSIIDHESLGDAITPESLLPFKVSDGQVRDAIRKWYGSRWFAPNRLKTAALTDTLKGVYLPYWTFDADVSARWTAEAGHYYYVTESYTENGQRKTREVQKIRWEPASGALQLFFNDELVPGTVGVHADLLQKIGDFPTASDLKPYSPEFVRGWTVERYQVDLRQAAQRGEAQMRARTRDACSAEVPGDTQRNLQVDATLSRRTFKHVLVPVWLVSYTYGSRSYQVLANGYTGALAGERPYSWIKIAFAVAAAAIALLVLVAVFGANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQI6</accession>
    <name>A0A0S2DQI6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DUF4377 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_24945</name>
        <name evidence="4" type="ORF">GLE_5147</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949589.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5147"/>
    <dbReference type="EnsemblBacteria" id="ALN60488">
        <property type="protein sequence ID" value="ALN60488"/>
        <property type="gene ID" value="GLE_5147"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5147"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5071"/>
    <dbReference type="OMA" id="KCSHPLI"/>
    <dbReference type="OrthoDB" id="1035553at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005184">
        <property type="entry name" value="DUF306_Meta_HslJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025485">
        <property type="entry name" value="DUF4377"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038670">
        <property type="entry name" value="HslJ-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14302">
        <property type="entry name" value="DUF4377"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03724">
        <property type="entry name" value="META"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242286" evidence="1">
        <location>
            <begin position="23"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="META" evidence="2">
        <location>
            <begin position="55"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4377" evidence="3">
        <location>
            <begin position="190"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW28415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="285" mass="30585" checksum="E068F39F63A3FB9A" modified="2016-02-17" version="1">MKIQRPLLLAAALSSVLLAACAAPSTSADKGSDMSKPKVDATIKNDAAPAARINLRGFTWNLDSAVDAAGKPIALLQREGKYGLKLSFVGDNLGVSGGCNHVGAGFKLDGDRLDIGDFRTTLMACQDQRLMQMDTAISEQLKGKASYAIEGEPPSPRLLLTTASGAKLTLSGEPTAETRYGSAGTTIFLEVDSQLRKCSHPLIPNHQCLWVRERAYDANGVALKPSDEWHFLYQDIEGYQHEAGIRNVVRVKKFDVKNPPADASSVAYVLDMVVESESVPAPNAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQL6</accession>
    <name>A0A0S2DQL6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fimbrial protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Type 1 fimbrial protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_00515</name>
        <name evidence="2" type="ORF">GLE_5459</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949823.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60800">
        <property type="protein sequence ID" value="ALN60800"/>
        <property type="gene ID" value="GLE_5459"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5459"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5374"/>
    <dbReference type="OMA" id="IENTCTV"/>
    <dbReference type="OrthoDB" id="951513at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009289">
        <property type="term" value="C:pilus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1090">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036937">
        <property type="entry name" value="Adhesion_dom_fimbrial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008966">
        <property type="entry name" value="Adhesion_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039458">
        <property type="entry name" value="FimA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16970">
        <property type="entry name" value="FimA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49401">
        <property type="entry name" value="SSF49401"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726829" evidence="1">
        <location>
            <begin position="22"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="178" mass="18005" checksum="2870973E6E0483C6" modified="2016-02-17" version="1">MKTASTAVLALALALPASALAADGTLRFEGSVIAPTCTLTNGPTPADIRVKLPTVAVSALSAAGQTAGRTPFFIRVADCDAATAQVQTYFEPGPTINTSSNNLTLQGGTGNASNIELQLLNADHSQVLLGNPLGLQNTQSVAVESGGAALRYYAQYVATGAATAGAANSSVTFTMIYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA35</accession>
    <name>A0A0S2DA35_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="2">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_0005</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0005"/>
    <dbReference type="REBASE" id="131995">
        <property type="entry name" value="M.LenC3ORF5543P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55364">
        <property type="protein sequence ID" value="ALN55364"/>
        <property type="gene ID" value="GLE_0005"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0005"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.7"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022749">
        <property type="entry name" value="D12N6_MeTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12161">
        <property type="entry name" value="HsdM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HsdM_N" evidence="4">
        <location>
            <begin position="25"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="N6_Mtase" evidence="3">
        <location>
            <begin position="169"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN55364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="686" mass="77178" checksum="8F727AE88E1513D3" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAA5</accession>
    <name>A0A0S2DAA5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Heat-shock protein Hsp70</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_01335</name>
        <name evidence="3" type="ORF">GLE_0084</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945783.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0084"/>
    <dbReference type="EnsemblBacteria" id="ALN55443">
        <property type="protein sequence ID" value="ALN55443"/>
        <property type="gene ID" value="GLE_0084"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0084"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.89"/>
    <dbReference type="OMA" id="FFIDEDP"/>
    <dbReference type="OrthoDB" id="410781at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="456" mass="49066" checksum="351F33F78F1E4D5D" modified="2016-02-17" version="1">MKIGIDFGTSYSAAAAVIDGEVRTVRFGQERQFRTTVYFPEAVPDLDKFELDDAMEAEVEALVRSARAEQSRNPGQARRSDLELRRDAVRAVRRQWLERQVREARASAASLQNAVYGEEAVEAYLIEGFGNLVQSPKSMLGYQLAPHVRQTIVGIAGYILEHIRLNASQQFGANVRAAVLGRPVQFRSSMGAAGGDQALEILREAAAGAGFDDVDFLEEPVAAALGHHAQSAQRHRALVVDIGGGTSDITLAEVGGAQPPRVLGSWGIARGGVDVDLALSLSRFMPLFGKGATRVPAHHFVEAATVHDVIRQRDFQRRDAYRDVPDPFGPRLIALQDTGNTTRLSRAVEAAKVELSSRERNRAALDYIETGLFQEVLAPDLAAAAEGFLGFLSELLGEVSAQIDAPPQVVFLTGGMSRAPYVRAAVQRCFPDAQLVAGDPSLGVVSGLAFAALAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAB8</accession>
    <name>A0A0S2DAB8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Spore coat U domain protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Spore coat protein U domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_01435</name>
        <name evidence="3" type="ORF">GLE_0100</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945795.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0100"/>
    <dbReference type="EnsemblBacteria" id="ALN55459">
        <property type="protein sequence ID" value="ALN55459"/>
        <property type="gene ID" value="GLE_0100"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0100"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.104"/>
    <dbReference type="OMA" id="TVTNDCS"/>
    <dbReference type="OrthoDB" id="1638330at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007893">
        <property type="entry name" value="Spore_coat_U"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05229">
        <property type="entry name" value="SCPU"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00972">
        <property type="entry name" value="SCPU"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0167">Capsid protein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0946">Virion</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726716" evidence="1">
        <location>
            <begin position="27"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="SCPU" evidence="2">
        <location>
            <begin position="99"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="SCPU" evidence="2">
        <location>
            <begin position="279"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="339" mass="34873" checksum="380E64D8C75748A2" modified="2016-02-17" version="1">MNARAAILRCALALFAALALGAPAHAATSCTASMTNLNFAATTGAAVDATATLTVTCSTGALSLLARARVNMCVSIFSGTDGGGTLAPRRMTNTPGDAMQMQLYTDGARSQIWGARGNATVPNFLPLQFDYEVIAIGGSQTLTATLYGRIPAQTALNAGTYRNRFTAAADTRIEFQYAEALLGTPPMPASCVSGGSTGTPSSFPFTVNGSVPNTCALSPKPVPDLAFGSVPGYVTANVDRTTAIGLTCTGRTAWQLGIGNGLNASGNIRRMRSAGGQFVPYELYRDSGRSQRWGTTLGTDTVSGTGTGAAQSQTVYGRVAPQTATPGSYTDTVVVTVTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAE0</accession>
    <name>A0A0S2DAE0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1080 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0163</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945839.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0163"/>
    <dbReference type="EnsemblBacteria" id="ALN55522">
        <property type="protein sequence ID" value="ALN55522"/>
        <property type="gene ID" value="GLE_0163"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0163"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.165"/>
    <dbReference type="OMA" id="TGPEIQV"/>
    <dbReference type="OrthoDB" id="1452706at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010496">
        <property type="entry name" value="3-keto-disaccharide_hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06439">
        <property type="entry name" value="DUF1080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594783" description="DUF1080 domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1080" evidence="2">
        <location>
            <begin position="37"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="236" mass="25636" checksum="B0BD72FB1F400D8C" modified="2016-02-17" version="1">MAIIRVPILICAALVACVLAGGPAPAAGRDAAAPRAGFVALFDGRSTQGWHLYGRRGEPVAGWSVRDGALVRSGAGGDLVSDAQFGDFELRLEWKIAPGGNSGVFYRVRENDEPVYHSALEYQVLDDRRHPDARNGADRLAGALYGLYPPARAAARPAGQWNAARIVARGDRVEHWLNGVRVAAFEIGSRDWNARLARSKFKDWPGFAGARRGAIALQDHGDEVAYRRIEIRALDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAK1</accession>
    <name>A0A0S2DAK1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AAA family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_01805</name>
        <name evidence="4" type="ORF">GLE_0187</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0187"/>
    <dbReference type="EnsemblBacteria" id="ALN55546">
        <property type="protein sequence ID" value="ALN55546"/>
        <property type="gene ID" value="GLE_0187"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0187"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.189"/>
    <dbReference type="OMA" id="MGNNVML"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020958">
        <property type="entry name" value="DUF3686"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12458">
        <property type="entry name" value="DUF3686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3686" evidence="3">
        <location>
            <begin position="47"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_5" evidence="2">
        <location>
            <begin position="1300"/>
            <end position="1426"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="819"/>
            <end position="862"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN55546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW24600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="1785" mass="198110" checksum="D17EC984C5FD4EAB" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAP3</accession>
    <name>A0A0S2DAP3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sporulation and cell division repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_0248</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945901.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0248"/>
    <dbReference type="EnsemblBacteria" id="ALN55607">
        <property type="protein sequence ID" value="ALN55607"/>
        <property type="gene ID" value="GLE_0248"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0248"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.250"/>
    <dbReference type="OMA" id="TNREMAV"/>
    <dbReference type="OrthoDB" id="1741144at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042834">
        <property type="term" value="F:peptidoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007730">
        <property type="entry name" value="SPOR-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036680">
        <property type="entry name" value="SPOR-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05036">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110997">
        <property type="entry name" value="SSF110997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51724">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="SPOR" evidence="3">
        <location>
            <begin position="226"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN55607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="305" mass="30929" checksum="68C3C8960D55BC3E" modified="2016-02-17" version="1">MAARRGKSQAKRNNQGNDSLPGWAWGVLGLLLGVVLILVVPKYFKADGKGDGFFRPQPNPDAQPAAVSAEEDAVAPEGSARPARAEAQAKADKPKGAAADKTKDGPEYDFYKLLPGKEVEMSDAELAATEAAEEQRRAAQQRRAGQIAAAQPTTAAATASGPVATTLPKPVDTLAPAPSKPPAPVATATAPPASSVAPKPPVVAAAQGTPAAPATATVAAAAAPAVSDNTRYLLQAGAFQASGQAEEMKAKIAMLGLGARVESAQIGGKTVYRVRMGPYGTAGDLADAKRKLADGGLPGMAIKVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAQ3</accession>
    <name>A0A0S2DAQ3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">MarR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_02230</name>
        <name evidence="3" type="ORF">GLE_0280</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945923.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55638">
        <property type="protein sequence ID" value="ALN55638"/>
        <property type="gene ID" value="GLE_0280"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0280"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.279"/>
    <dbReference type="OMA" id="MQRKGPM"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="238" mass="25784" checksum="4FB5A5454555F90C" modified="2016-02-17" version="1">MSDPAFHLRQTALGLERLGGLMRAQQWREPDAYALHPAQRALLELLGEDKRGWRVGELAQRLGVSAASASDTIAALQARELVRRERDPDDGRAVRVHPSRRGLAWLRRSRARGGLGERLLATLAPDELAAFSRSLQLLILQAQREGLATGLRTCAGCEFFRPFEGGGDAPHYCALVGAAFGDAQLRVDCAEHRPRAADARAGALDAVAARFRAGAGDRRDTTSRRGPAPKRTHSAAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAW8</accession>
    <name>A0A0S2DAW8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_0316</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0316"/>
    <dbReference type="EnsemblBacteria" id="ALN55674">
        <property type="protein sequence ID" value="ALN55674"/>
        <property type="gene ID" value="GLE_0316"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0316"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.313"/>
    <dbReference type="OMA" id="AFPVHVI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003788">
        <property type="entry name" value="NDUFAF7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038375">
        <property type="entry name" value="NDUFAF7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049">
        <property type="entry name" value="PTHR12049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02636">
        <property type="entry name" value="Methyltransf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN55674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="394" mass="43101" checksum="7419AEEC14A66636" modified="2016-02-17" version="1">MTALDLPLPDPDALAHSARLSRLIHEQIAAAGGAIAFSRFMELALYAPGLGYYSAGASKFGGEGDFVTAPELGPVFAACTAQALAPALQQIGPQARLLELGGGTGAFAEVALKRLLELDALPDRYAILEPSAQLRERQRERLMQRLAPPLFELVEWLDGPFGDEWEGVVFANEVIDALPTPRFGIRDGEVYEEHVTSDGERFARELRPADSFLANAVGHIERGLERRFADGYRSEVLPQLPYWIQAVSGGLRRGALLFADYGYARGEFYAPERDDGTLRAYYRHRVHGEPLLWPGLQDITASVDFTALAEAGVAAGFDLAGYCSQASFLLGNGLDGVLKRIESIADPVEKQRRLNEVKKLTLPSEMGERFQVMGLQKDVELGVAFMVGDLSHRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBE4</accession>
    <name>A0A0S2DBE4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fimbrial protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_0351</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the N-Me-Phe pilin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945973.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0351"/>
    <dbReference type="EnsemblBacteria" id="ALN55709">
        <property type="protein sequence ID" value="ALN55709"/>
        <property type="gene ID" value="GLE_0351"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0351"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.348"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009289">
        <property type="term" value="C:pilus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025640">
        <property type="entry name" value="GYF_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001082">
        <property type="entry name" value="Pilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14237">
        <property type="entry name" value="GYF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00114">
        <property type="entry name" value="Pilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="199"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="GYF_2" evidence="4">
        <location>
            <begin position="4"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="87"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN55709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="338" mass="35070" checksum="026CD03D539C91AB" modified="2016-02-17" version="1">MTHWYYHEPSQGRVGPIDADALREHVRAGRVRRDTLVWRAGLSGWLPLQQVEDELGLADAPPPLPPGAAATPIAATPIAAPQAPLTAATPNAPAATPAPTDSAPAPAAAPASPAATASPAAPVAAPAPQGRADFSAAVAATETPQPAAQAPIGASAPQPAEAAPAQPQRSVSPADYAPAHVARRQQAAPPPKRGMSGCLIALIVVAVLAIPVLGILAAIALPAYQDYTHRAKLAGVMAEAGSYKLQVAEHYLEHEGCPNNASPGFRPAADYAGPQLASVEFGRFKDSGQCAIQLELRGFDNRHLDGRKLWLSFDPNSHEWTCSTDIDKPVLVPQSCRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBE9</accession>
    <name>A0A0S2DBE9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chromosome replication initiation inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">iciA</name>
        <name evidence="3" type="ORF">GLE_0502</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946083.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0502"/>
    <dbReference type="EnsemblBacteria" id="ALN55860">
        <property type="protein sequence ID" value="ALN55860"/>
        <property type="gene ID" value="GLE_0502"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0502"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.497"/>
    <dbReference type="OMA" id="WRNGGQL"/>
    <dbReference type="OrthoDB" id="951478at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017685">
        <property type="entry name" value="ArgP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03298">
        <property type="entry name" value="argP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="298" mass="32642" checksum="62005425B4C20CE5" modified="2016-02-17" version="1">MDLLHPQLAAFAAVLEEGSFEAAARRLSVTASAVSQRIKALEDRLGQVLVVRQAPCRPTRAGERLLRRVRPMQALEAEALADFLPEDREAAPTRPVVVAVNDDSLDSWFLAAMARLHRQHGYLFDIRVDDQDHTLDLLRNGTALGAITAEANALQGCNVHPLGVMRYRAIASPQFAARHFADGMNAAALARAPMIVFNRKDELQWRYVRRITRARLAPPVHYVPTSTGFVEASALGLGWCLAPESLTGAALRGGRIVLVDPGRSLDVPLYWQHAAVRSSVLQRIGAALREAATEALRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBS3</accession>
    <name>A0A0S2DBS3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transferrin-binding protein-like solute binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_15695</name>
        <name evidence="5" type="ORF">FE772_03785</name>
        <name evidence="3" type="ORF">GLE_0616</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000040">
        <property type="protein sequence ID" value="OPD63070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946165.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0616"/>
    <dbReference type="EnsemblBacteria" id="ALN55974">
        <property type="protein sequence ID" value="ALN55974"/>
        <property type="gene ID" value="GLE_0616"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63070">
        <property type="protein sequence ID" value="OPD63070"/>
        <property type="gene ID" value="BV903_15695"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0616"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.608"/>
    <dbReference type="OMA" id="FGEWSQT"/>
    <dbReference type="OrthoDB" id="1369721at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001677">
        <property type="entry name" value="TbpB_B_D"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01298">
        <property type="entry name" value="TbpB_B_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594726" evidence="1">
        <location>
            <begin position="23"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="TbpB_B_D" evidence="2">
        <location>
            <begin position="123"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD63070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW24921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="246" mass="24416" checksum="17D8B73E0A5071ED" modified="2016-02-17" version="1">MKRMSLTLSALALAALAGTAQAAVVGDQSDNTYVEAGVSTVNAGPHIAGRPGIGVYTMGTDRKVDFQALQTFAPADANGVSSLVSPITPPTHSGMGVFHFAKIAGHNVYFGEWSQSAPTDGTHTVYYAGDNAGTTVPASGTATYTVAGLNQYNGANKLNGTFNANFGAGQLSGSLSNGTVTVDIGTAAISGTGFSGSGASATVGGATVATGGVSGQFFGANAAALAGVTRFDDRLYDTAFGGTKNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBT5</accession>
    <name>A0A0S2DBT5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">3-hydroxyisobutyrate dehydrogenase</fullName>
            <shortName evidence="5">HIBADH</shortName>
            <ecNumber evidence="5">1.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mmsB</name>
        <name evidence="8" type="ORF">GLE_0579</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>3-hydroxy-2-methylpropanoate + NAD(+) = 2-methyl-3-oxopropanoate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:17681"/>
            <dbReference type="ChEBI" id="CHEBI:11805"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57700"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid degradation; L-valine degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the HIBADH-related family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.31" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946138.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0579"/>
    <dbReference type="EnsemblBacteria" id="ALN55937">
        <property type="protein sequence ID" value="ALN55937"/>
        <property type="gene ID" value="GLE_0579"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0579"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.572"/>
    <dbReference type="OMA" id="VTMIATC"/>
    <dbReference type="OrthoDB" id="1245550at2"/>
    <dbReference type="UniPathway" id="UPA00362"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008442">
        <property type="term" value="F:3-hydroxyisobutyrate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002204">
        <property type="entry name" value="3-OH-isobutyrate_DH-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011548">
        <property type="entry name" value="HIBADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="NADP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01692">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00895">
        <property type="entry name" value="3_HYDROXYISOBUT_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0101">Branched-chain amino acid catabolism</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_binding_2" evidence="6">
        <location>
            <begin position="3"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="NAD_binding_11" evidence="7">
        <location>
            <begin position="165"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000103-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU910714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN55937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="299" mass="29396" checksum="2326FA0C7087097A" modified="2016-02-17" version="1">MSRIAFIGLGHMGGPMAANLLKAGHELQVFDLVPAAVEAAVALGARAAASAAEAVDGAEVAISMLPASRHVEGLYLGADGLLARLAPQALAIDCSTIAPASAQKVAAAAAARGVAMIDAPVSGGTAGAAAGTLTFIVGGEAAALERARPLLQAMGRNVFHMGASGAGQVAKLCNNMALGVIMAATGEALALGAAHGLDPAALSQMMAVSTGRSWATEVCNPWPGVLENAPASRGYSGGFGSDLMLKDLGLAAEAAMGVGSPIPLGELARNLYALNARAGRGGLDFSSVIQLLAKPAAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCD2</accession>
    <name>A0A0S2DCD2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ion channel</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Ion channel family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Two pore domain potassium channel family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_09650</name>
        <name evidence="5" type="ORF">FE772_04850</name>
        <name evidence="3" type="ORF">GLE_0836</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000021">
        <property type="protein sequence ID" value="OPD64142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946333.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0836"/>
    <dbReference type="EnsemblBacteria" id="ALN56194">
        <property type="protein sequence ID" value="ALN56194"/>
        <property type="gene ID" value="GLE_0836"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64142">
        <property type="protein sequence ID" value="OPD64142"/>
        <property type="gene ID" value="BV903_09650"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0836"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.825"/>
    <dbReference type="OMA" id="LVMLEQF"/>
    <dbReference type="OrthoDB" id="1991946at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Ion_trans_2" evidence="2">
        <location>
            <begin position="133"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD64142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="226" mass="24361" checksum="03EB17A3E45DDB6D" modified="2016-02-17" version="1">MPSYASLKWRALARRHPSAFLLAAQLLSLAVYPLFEPAGGGRVVFGAFGVLVLALAVWVVNRSPAIKWIAWIIAIPAFALSVLSVLFASPGLLVLSSALEAALYFYAAGALIAYMMSDHKVTADELFAAGATFTLLAWGFAYAFLVCQAWYPDSFVGAQRPGEPRTWLELLFLSFTNLSAVGLGDILPMSPAARVLTMFEQFAGVGYIAAVVSRLIGLTMLRQPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCH5</accession>
    <name>A0A0S2DCH5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine triad (HIT) protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0871</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56229">
        <property type="protein sequence ID" value="ALN56229"/>
        <property type="gene ID" value="GLE_0871"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0871"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.860"/>
    <dbReference type="OMA" id="RGFFWPR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46648">
        <property type="entry name" value="PTHR46648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00332">
        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="2">
        <location>
            <begin position="6"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="1">
        <location>
            <begin position="98"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="145" mass="15575" checksum="8E37502952F7991B" modified="2016-02-17" version="1">MATSCVFCELLAGRAPASFVHRDEHLAAFVDLRQAVPGHVLIVPNRHVETLYELDEATAGRMMALAVRVARALAAEFGPPGLNLWQSNGEAGGQEVPHVHLHVQPRRVGDGLMRVYPKGIPAPGPRPVLDELAARLAARLPATSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCK6</accession>
    <name>A0A0S2DCK6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Serine/threonine protein kinase protein family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0865</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946354.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0865"/>
    <dbReference type="EnsemblBacteria" id="ALN56223">
        <property type="protein sequence ID" value="ALN56223"/>
        <property type="gene ID" value="GLE_0865"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0865"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.854"/>
    <dbReference type="OMA" id="GAAMYQR"/>
    <dbReference type="OrthoDB" id="607446at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="218" mass="25906" checksum="E95442C0358072CC" modified="2016-02-17" version="1">MSDVIEVTALKADSFGRIALMRDSRGLFVRRDLSHVPWWLRLPAWWLARREARALERIDGLEATPRLLGWDGRKLDRSYMEGAAMYQRPPRGDLAYFRRARRLLQRLHRRGLAHNDLAKEANWLVLADGAPAIIDFQLAVRGDPRSRWMRLLAREDLRHLLKHKRTYCPQHLTPVERRVLKRHSWVRELWFVTGKPVYRFVTRRILHWEDNEGQGPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCN2</accession>
    <name>A0A0S2DCN2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Biotin carboxylase</fullName>
            <ecNumber evidence="5 13">6.3.4.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 13">Acetyl-coenzyme A carboxylase biotin carboxylase subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">accC</name>
        <name evidence="17" type="ORF">BV903_19900</name>
        <name evidence="19" type="ORF">D9T17_23335</name>
        <name evidence="18" type="ORF">FE772_04515</name>
        <name evidence="16" type="ORF">GLE_0767</name>
    </gene>
    <organism evidence="16 20">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="16 20" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 20">C3</strain>
        </source>
    </reference>
    <reference evidence="17 21" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 21">B25</strain>
        </source>
    </reference>
    <reference evidence="19 22" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 22">OH11</strain>
        </source>
    </reference>
    <reference evidence="18 23" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 23">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13">This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>ATP + hydrogencarbonate + N(6)-biotinyl-L-lysyl-[protein] = ADP + H(+) + N(6)-carboxybiotinyl-L-lysyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13501"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.14"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 13">Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.14" evidence="5 13"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000059">
        <property type="protein sequence ID" value="OPD62150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000058">
        <property type="protein sequence ID" value="ROU04582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946284.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000058.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0767"/>
    <dbReference type="EnsemblBacteria" id="ALN56125">
        <property type="protein sequence ID" value="ALN56125"/>
        <property type="gene ID" value="GLE_0767"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62150">
        <property type="protein sequence ID" value="OPD62150"/>
        <property type="gene ID" value="BV903_19900"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0767"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.756"/>
    <dbReference type="OMA" id="FVEICSH"/>
    <dbReference type="OrthoDB" id="361205at2"/>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004075">
        <property type="term" value="F:biotin carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004549">
        <property type="entry name" value="Acetyl_CoA_COase_biotin_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00514">
        <property type="entry name" value="accC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 12 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 13" id="KW-0092">Biotin</keyword>
    <keyword evidence="13" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="7 13 16" id="KW-0436">Ligase</keyword>
    <keyword evidence="13" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 12 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="15">
        <location>
            <begin position="1"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="14">
        <location>
            <begin position="120"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ALN56125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OPD62150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="QCW25043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ROU04582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="455" mass="49623" checksum="C9E1010AA0BE8952" modified="2016-02-17" version="1">MLDKVVIANRGEIALRILRACHALGIRTVAVHSTVDRNLKHVAMADESVCIGPAPSSESYLNMASIIAAAEVTDAQAIHPGYGFLSENADFAERVEQSGFVFIGPRAETIRLMGDKVEAIRAMKDAGVPCVPGSGGPLGDDNAANIKIAREIGYPIIVKAAGGGGGRGMRVVHTEAHLNAAIQTTKSEAKAAFGNDMVYMEKFLENPRHVEIQVLADGQGNAIHLGERDCSMQRRHQKVVEEAPAPGITPEQRAEIGKVCVEACIRIGYRGAGTFEFLYENGRFYFIEMNTRIQVEHPVTELVTGIDLVREQLMIAAGRKLSIKQEDVVLEGHAIECRINAEDPETFMPCPGPINHFHAPGGPGVRVDSHIYEGYRVPPNYDSMIGKLIVHGPDRETAIARMRVALSEMVVDGIKTNIPLQQRILSDAGFQQGGMNIHYLEKRLKEQKEKTIAIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCQ1</accession>
    <name>A0A0S2DCQ1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0947</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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</entry>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
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        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF06594"/>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="236" mass="24460" checksum="CD21AF86734F2448" modified="2016-02-17" version="1">MPIFDPSPATAHAPSAEMRRIAGPAIDSGTDASARIKQAHSRRSAPGLLAASLLAASLFVAGSPAALASSQRLSAIVGSTGDDVLYGTAQADTIQGLDGNDALYGLGGDDVLDSGDGDDVLTGGTGDDALYSGQGNSFFVFYAGDGHDRVYHSDPVGQFLSTLQFQAGVDPAATTVERSGDDLIVRYGNADSVTLVDYFPGGDDPWPRGIDEFWFAQNEVWDAAQILSRLPPGHGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD71</accession>
    <name>A0A0S2DD71_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alcohol dehydrogenase</fullName>
            <ecNumber evidence="6">1.1.99.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">alkJ</name>
        <name evidence="6" type="ORF">GLE_1081</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.99.-" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1081"/>
    <dbReference type="EnsemblBacteria" id="ALN56439">
        <property type="protein sequence ID" value="ALN56439"/>
        <property type="gene ID" value="GLE_1081"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1081"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1068"/>
    <dbReference type="OMA" id="GWGWQDV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="PTHR11552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMC_OxRdtase_N" evidence="4">
        <location>
            <begin position="82"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="GMC_OxRdtase_N" evidence="5">
        <location>
            <begin position="254"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN56439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="530" mass="58103" checksum="8D60E5810167A2D4" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDV1</accession>
    <name>A0A0S2DDV1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_07050</name>
        <name evidence="1" type="ORF">GLE_1316</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946682.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56673">
        <property type="protein sequence ID" value="ALN56673"/>
        <property type="gene ID" value="GLE_1316"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1316"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1300"/>
    <dbReference type="OrthoDB" id="2168675at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="189" mass="20479" checksum="A88F944A6BC38247" modified="2016-02-17" version="1">MFGTSLSLRAPARVRAAIAPPAARRRASAPFAAFRAFALTLLMLFVHGAGADPVAADQRLAIVKQNFTALKQNYSIAKMQLQMGQTTPASVSFTLARAQSQQMVSNLAILRNDNQHTLDNGLYLNGAAQQQAVNYTDVAKSLTQQLQTRLLILSMQPASQLDLVLADQSLTQLTLKLTQLEQAMIAAQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDY6</accession>
    <name>A0A0S2DDY6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF488 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_07780</name>
        <name evidence="1" type="ORF">GLE_1481</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946810.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56838">
        <property type="protein sequence ID" value="ALN56838"/>
        <property type="gene ID" value="GLE_1481"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1481"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1462"/>
    <dbReference type="OMA" id="FSVGCYC"/>
    <dbReference type="OrthoDB" id="1831995at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007438">
        <property type="entry name" value="DUF488"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04343">
        <property type="entry name" value="DUF488"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="128" mass="14284" checksum="1E281426706D2979" modified="2016-02-17" version="1">MAIRIVRLGTARGPREGLRIGTVRRPPRGVPKSEFAKQDWYDVWFPTLAPSLETMKQAQAARTPAQWNAFVRKYRAEMKGHDAQHALDLLAAMSHGSDLSVGCYCEDESHCHRSILRELLADKGAALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE34</accession>
    <name>A0A0S2DE34_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase, M16 family</fullName>
            <ecNumber evidence="6">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_1447</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M16 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946780.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1447"/>
    <dbReference type="EnsemblBacteria" id="ALN56804">
        <property type="protein sequence ID" value="ALN56804"/>
        <property type="gene ID" value="GLE_1447"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1447"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1427"/>
    <dbReference type="OMA" id="NYPYVIY"/>
    <dbReference type="OrthoDB" id="1188251at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595039" evidence="3">
        <location>
            <begin position="20"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16" evidence="4">
        <location>
            <begin position="47"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="5">
        <location>
            <begin position="203"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN56804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="468" mass="50637" checksum="7F4022327BCE577F" modified="2016-02-17" version="1">MRKRHLCVLLAGLTTLASAAFATASAAESDRWQVPVAVKKLDNGLTVVVSTDHSSPTVGVSVVYHVGMRLEPKNRTGFAHLFEHLMFQGTPAAPKGVFDQVISGGGGRNNGSTRPDFTNYIEVAPVSALERILWLEADRMKTLDFNPTTLKNQQDVVKEEIRVNVKNQPYGGFMWIDIGQHAFNKWENNHDGYGSFQDLENASLADVQSFHRDYYGPNNAVLGIAGDISPEEAFKLADKYFGAVAGRPTPAAPDYSEGLNTAEKRINQTDALAQVPAIAAGWKMPARGSRDQAPMAVLGSVLAGDDASRLYQSLVKRRQIALNIEPLYGLTDPWSYNGPTLYTLFAMYKPDSSADAVLAAIDEEVANIAKNGVDAATLKRVKTKMLADWYNGLEPFIDRADALAVLQTLWGDANVVNKIPTLIEGVTSADLQRVAKTYLTQANRTVIDRRPAAAAPAPAAAAPAAAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE79</accession>
    <name>A0A0S2DE79_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Two-component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1495</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1495"/>
    <dbReference type="EnsemblBacteria" id="ALN56852">
        <property type="protein sequence ID" value="ALN56852"/>
        <property type="gene ID" value="GLE_1495"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1495"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1476"/>
    <dbReference type="OMA" id="SERECEV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005143">
        <property type="entry name" value="TF_LuxR_autoind-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036693">
        <property type="entry name" value="TF_LuxR_autoind-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03472">
        <property type="entry name" value="Autoind_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75516">
        <property type="entry name" value="SSF75516"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="182"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="251" mass="28162" checksum="CA59211BEAB3B15D" modified="2016-02-17" version="1">MIRHGMEYWDHIDRVLRAATLDEVKSVTSAFSRAVGFHNHGYATKLREPLPGGSDFVFFEDFDSDWSKTYPALAAPDAERSDPRITLSREGLPAVAWNSRGRTTWEPRPQLYQIGRRTLMAAGEFGLHGGITVPSWSPGTQWSFTTFTVNALADPRELVPTLGQAVYFVSCMHAAMDRLLRRPRHAPKLSERECEVLRWSAVGKTSWEISMILQISERTVNFHLQQVARKLGVKGRRAACARAVALGLIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEJ8</accession>
    <name>A0A0S2DEJ8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glucan biosynthesis protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Periplasmic glucan biosynthesis protein, MdoG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_08500</name>
        <name evidence="7" type="ORF">GLE_1639</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycan metabolism; osmoregulated periplasmic glucan (OPG) biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the OpgD/OpgG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946936.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1639"/>
    <dbReference type="EnsemblBacteria" id="ALN56996">
        <property type="protein sequence ID" value="ALN56996"/>
        <property type="gene ID" value="GLE_1639"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1639"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1618"/>
    <dbReference type="OMA" id="KRPSAWI"/>
    <dbReference type="OrthoDB" id="1049230at2"/>
    <dbReference type="UniPathway" id="UPA00637"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016051">
        <property type="term" value="P:carbohydrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014438">
        <property type="entry name" value="Glucan_biosyn_MdoG/MdoD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007444">
        <property type="entry name" value="Glucan_biosyn_MdoG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30504">
        <property type="entry name" value="PTHR30504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04349">
        <property type="entry name" value="MdoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006281">
        <property type="entry name" value="MdoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242184" evidence="5">
        <location>
            <begin position="20"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="MdoG" evidence="6">
        <location>
            <begin position="37"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN56996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW25700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="508" mass="56285" checksum="B58008D63BDE23EC" modified="2016-02-17" version="1">MHRRELIKAGLGLPLAAWAAGGAWPAWAEAAGPAQAFDADTVPALARALAAKPFRAASSELPAGLGEVDYDRWRDIRFDPGQALWKNDGLPFQLQLFHRAFLFKQRVELNLVEAGQARPVRYRSELFDFGKAPRPPADADLGFAGFRVHAPINRKDYFDEVCAFLGASYFRAVARDLLYGLSARGLALNTGAGDREEFPAFVSFWIERPAKSAASIVVHALLDSPSTAGAMRFVVTPGADTTFDTSLRLYPRVALERAGIAPLTSMYHFDDTDRRGVDDFRPAVHDSDGLALFNGAGEQIWRPLHNPKNVQESAFQDRRPRAFGLMQRKRAFADYADSEAHYERRPSLWVEPVGDWGEGAVHLVEIPTGDEYHDNVVAFWRPRAPLAAGREHRFDYRLHWCAKHAWKPELATVSRTRIGAGGRGARLIVLDFDGGRLPRLARDTAMRAVVWASAGRIANASARAIDGSGAWRLSFELQPGDARAVELRAVMEDASGPVSETWLYRWTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEP8</accession>
    <name>A0A0S2DEP8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">creC</name>
        <name evidence="13" type="ORF">BV903_06970</name>
        <name evidence="14" type="ORF">FE772_08460</name>
        <name evidence="12" type="ORF">GLE_1629</name>
    </gene>
    <organism evidence="12 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">C3</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">B25</strain>
        </source>
    </reference>
    <reference evidence="14 17" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000013">
        <property type="protein sequence ID" value="OPD64628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946934.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1629"/>
    <dbReference type="EnsemblBacteria" id="ALN56986">
        <property type="protein sequence ID" value="ALN56986"/>
        <property type="gene ID" value="GLE_1629"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64628">
        <property type="protein sequence ID" value="OPD64628"/>
        <property type="gene ID" value="BV903_06970"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1629"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1610"/>
    <dbReference type="OMA" id="RWNDVYL"/>
    <dbReference type="OrthoDB" id="1827824at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029151">
        <property type="entry name" value="Sensor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="11">
        <location>
            <begin position="205"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="10">
        <location>
            <begin position="262"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN56986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OPD64628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW25694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="480" mass="51165" checksum="364FDAD06E9DC0A9" modified="2016-02-17" version="1">MRIGLRIFLGYFLIVALAATLLARVFVAEVKPGVRQAMEDTLVDTANVLAELAADDFLAGRIDQGDFAKRVRALSARDVGAAIWGFRKRSSSYRVYVTDARGIVVFDSSGRDVGQDYSRWNDVYLTLRGRYGARSSPDAAGNPDDTVMHVAAPIRDDDGRIVGALSVAKPNSAIAPFIARSQGVVARWGFVLMGAALLVGVGVSWWLSRQIGLLRRYANAVTAGARATAPDAAGEFGDLGRALETMRSRLEGKQYVEQYVHTLTHEMKSPLAAIRGSAELLESPPGEGGMADADRARFAGSIRAQAERLAQMIDKLLALAAVEHRQSLERPEPVALAAIAQEAAGHCAQRLRDSGAKLLLDLEPNLPAVQGDAFLLRQALVNLIDNAADFSPAGGEIALRLRRDGDRQRIEVGDRGPGVPDYALGRVFERFYSLPRPAGGSRSSGLGLCFVAEVASLHGGEAALANREGGGAQASLSVPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEW4</accession>
    <name>A0A0S2DEW4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNA polymerase-binding transcription factor DksA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 8" type="primary">dksA</name>
        <name evidence="9" type="ORF">FE772_09375</name>
        <name evidence="8" type="ORF">GLE_1827</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Interacts directly with the RNA polymerase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DksA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947077.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1827"/>
    <dbReference type="EnsemblBacteria" id="ALN57179">
        <property type="protein sequence ID" value="ALN57179"/>
        <property type="gene ID" value="GLE_1827"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1827"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1798"/>
    <dbReference type="OMA" id="RATLCMT"/>
    <dbReference type="OrthoDB" id="1932026at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00926">
        <property type="entry name" value="DksA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012784">
        <property type="entry name" value="DksA_RNA_pol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037187">
        <property type="entry name" value="DnaK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000962">
        <property type="entry name" value="Znf_DskA_TraR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01258">
        <property type="entry name" value="zf-dskA_traR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109635">
        <property type="entry name" value="SSF109635"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02420">
        <property type="entry name" value="dksA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51128">
        <property type="entry name" value="ZF_DKSA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DksA C4-type" evidence="7">
        <location>
            <begin position="304"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="dksA C4-type" evidence="5">
        <location>
            <begin position="347"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="285"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN57179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW25841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="384" mass="40689" checksum="25CC45197DC33DDA" modified="2016-02-17" version="1">MAVKKPAKKAAKAVNKTVKPAAKKVAKPAPKTAAKAPAKVAAKKVAAKAPAKAAKKTVAAKPVAKKAAPAPAKKAPAKPAPATAKKPAAAPAAAKKGAAAKPQVPIKDTNKPQVPVKDPPAKQAPTKDSGAKTPKAAPAKEAPIKETALAKAGVKKVEAKLPQADKTKPAQAAAKTPPQSVPPAAPASAAKQADSIISDQSKNTVTQTASSNRPAGKVAVAVTTKTPASPAPKTKVKVVPYKNDPTTGRPIVPEGYKPTADEEYMNPLQLEYFRQRLLQWRADLVEESKQTIENLKDEVRDVGDEAERATRETENSLELRTRDRYRKLISKIDSTLKRVDSGDYGFCVDTGEDIGLDRLEARLTAERTIDAQERWEHMQKQMGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEZ3</accession>
    <name>A0A0S2DEZ3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-binding response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FE772_09195</name>
        <name evidence="6" type="ORF">GLE_1788</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947048.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1788"/>
    <dbReference type="EnsemblBacteria" id="ALN57141">
        <property type="protein sequence ID" value="ALN57141"/>
        <property type="gene ID" value="GLE_1788"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1788"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1761"/>
    <dbReference type="OMA" id="QIISEVW"/>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="126"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="126"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW25813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="229" mass="25625" checksum="149B6CEFAF8C12F3" modified="2016-02-17" version="1">MTDILLIEDDERLGSLVAHYLGKHGYDVALETDGARAVAAILELQPAVVLLDVSLPGQDGFEICRAVRSRYTGVICMLTARTDDIDQVLGLELGADDYIGKPIEPRVLLARLRAHLRRDHAARHGGKVMRFGQLRIDCETREATLRESRIDLTTAEFDLLVLLAGRAGQILSRDDLLQTLRGIQFDGLDRSIDARISRLRRKLGDLAEEPERIKTVRGKGYLFNRAAWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEZ4</accession>
    <name>A0A0S2DEZ4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MltA-interacting</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">mipA</name>
        <name evidence="7" type="ORF">BV903_21830</name>
        <name evidence="6" type="ORF">GLE_1522</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">B25</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MipA/OmpV family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000072">
        <property type="protein sequence ID" value="OPD61817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946846.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000072.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56879">
        <property type="protein sequence ID" value="ALN56879"/>
        <property type="gene ID" value="GLE_1522"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61817">
        <property type="protein sequence ID" value="OPD61817"/>
        <property type="gene ID" value="BV903_21830"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1522"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1504"/>
    <dbReference type="OMA" id="EVKDSPM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010583">
        <property type="entry name" value="MipA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38776">
        <property type="entry name" value="PTHR38776"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06629">
        <property type="entry name" value="MipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595442" evidence="5">
        <location>
            <begin position="21"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN56879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD61817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="267" mass="29596" checksum="32081ECE2E7DB181" modified="2016-02-17" version="1">MRIVRIVPLLLLSFPLALSAQVRKEGEERADMAPANWSVGIAAGSRNELYAGEGNHTRVIPFFGYEGERFYLRGITAGYYLVKSDEFAFDVFVGGRLDAMDRKDFGRRELAKRGIDRDLLSDRDDSVDAGASVSWRGSAGELQLEVKADILDVSGGYEADVSYRYPMQAGEWLLTPAVGVSWMSKDLANYYYGTLDKEVRRGVVSYRPGSVTIPSVSLTVARPFAEKWRFMANVGYQVLPDEISDSPLIAEDTDGVAQAFFGVVRSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF78</accession>
    <name>A0A0S2DF78_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glutamate 5-kinase</fullName>
            <ecNumber evidence="8">2.7.2.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Gamma-glutamyl kinase</fullName>
            <shortName evidence="8">GK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">proB</name>
        <name evidence="11" type="ORF">GLE_1844</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + L-glutamate = ADP + L-glutamyl 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14877"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the glutamate 5-kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.11" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1844"/>
    <dbReference type="EnsemblBacteria" id="ALN57196">
        <property type="protein sequence ID" value="ALN57196"/>
        <property type="gene ID" value="GLE_1844"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1844"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1815"/>
    <dbReference type="OMA" id="TVIHRDN"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00359"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004349">
        <property type="term" value="F:glutamate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00456">
        <property type="entry name" value="ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011529">
        <property type="entry name" value="Glu_5kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005715">
        <property type="entry name" value="Glu_5kinase/COase_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019797">
        <property type="entry name" value="Glutamate_5-kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000729">
        <property type="entry name" value="GK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01027">
        <property type="entry name" value="proB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00902">
        <property type="entry name" value="GLUTAMATE_5_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 8" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PUA" evidence="10">
        <location>
            <begin position="284"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="381"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="177"/>
            <end position="178"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="219"/>
            <end position="225"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN57196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="404" mass="42122" checksum="1E6F3D0828C8401D" modified="2016-02-17" version="1">MSATARDFAAQPLPPWRRAVLKVGSSLLAGFEGGGLDPRYAAGLARFIESARERQREVVLVSSGAVAAGRGRIAAGGDGLVLRQALASLGQASLIAFWQQLSSVPVAQVLLTHDDLRNRRRYLNARASLRELLRLGALPVINENDTVAVDELKLGDNDNLAAAVASLVDADLLLIATDIGGLYSGHPQRDPNARPIERVAAVTPELLLAASGGAGALGTGGMRTKLEAAAKAATAGVATALFCGRDNDVVEALARDTLHGTLVSAQNDRLRARKQWLRHAPASGGLRIDAGAANALRVRGASLLPGGVVAVEGEFRRGDVVELRVAEGGEAVGRGLVQYNSAELGRIKGRHSRDIEAVLGFRYGESVVHRDDLVMLGGRAADPHAVDSGGNEPASGPATDEVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFF0</accession>
    <name>A0A0S2DFF0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_09075</name>
        <name evidence="2" type="ORF">GLE_1763</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <source>
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</entry>
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</entry>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
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                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
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        </source>
    </evidence>
    <sequence length="176" mass="18336" checksum="61042E0C6DD26579" modified="2016-02-17" version="1">MTEVFLGQITTFGFNFAPKNFAFCNGQLLAIAQNQALFSLLGTMYGGNGTTNFALPDLRGRTPVGAGNSVDPGWNPAPYPQGQSGGVENVTLLPTQMPNHNHTLGCNTGAATSRNPNGLFLGTTDKEIYSATGGPQVALSAATIGTAGSTQPHSNVQPYLAINFCIALNGIYPSRN</sequence>
</entry>
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            <fullName evidence="1">Uncharacterized protein</fullName>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="38" mass="4242" checksum="F154ED3D1C217D5B" modified="2016-02-17" version="1">MVTARRRCGPAARAAAGRSLPLRHALPATRFDRRRRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG48</accession>
    <name>A0A0S2DG48_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2061</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="47" mass="5377" checksum="B94B4F9A36AEDD5E" modified="2016-02-17" version="1">MACGLVGSGWGWSRGRPLYGLRTAIKTNRNVEINANFYLRISWAYKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG75</accession>
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            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="78"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="359" mass="39265" checksum="DD7F3C067B3EDB73" modified="2016-02-17" version="1">MTAVLRQHAEIQFAEELEQLAKADDRQRPANWKLSPWAVVTYLIGGKLDNGFEVSAKYIGNRRLMEIAVATVATDRALLLFGVPGTAKSWVSEHLSAAISGDSTMLIQGTAGTSEEQIRYGWNYAQLLAHGPSENALVPSPMMNAMKLGKIARVEELTRIPADVQDTLITVLSEKTLPVPELGSEVQAARGFSVIATANNRDKGVNELSSALKRRFNTVILPVPSSEEEEVSIVVKRVHELGRALELPAEPPALKEVARIVRIFRELRNGQTEDGKSKLKTPSSTLSTAEAISVINNGMALAGHFGDGVLRAADMAAGMIGAVVKDPVQDQVVWTEYLETVVKERAEWKDLYRAFREQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGE5</accession>
    <name>A0A0S2DGE5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Capsular biosynthesis protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="16">Polysaccharide biosynthesis/export protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">FE772_11395</name>
        <name evidence="16" type="ORF">GLE_2261</name>
    </gene>
    <organism evidence="16 18">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="16 18" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">C3</strain>
        </source>
    </reference>
    <reference evidence="17 19" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the BexD/CtrA/VexA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW26187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947406.1">
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_2261"/>
    <dbReference type="EnsemblBacteria" id="ALN57610">
        <property type="protein sequence ID" value="ALN57610"/>
        <property type="gene ID" value="GLE_2261"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2261"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2226"/>
    <dbReference type="OMA" id="TKGGQFY"/>
    <dbReference type="OrthoDB" id="687725at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015159">
        <property type="term" value="F:polysaccharide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Poly_export"/>
    </dbReference>
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        <property type="entry name" value="Soluble_ligand-bd"/>
    </dbReference>
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        <property type="entry name" value="Wza_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02563">
        <property type="entry name" value="Poly_export"/>
        <property type="match status" value="1"/>
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    </dbReference>
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    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
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        <location>
            <begin position="247"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="Wza_C" evidence="15">
        <location>
            <begin position="334"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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            <dbReference type="Pfam" id="PF18412"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN57610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="QCW26187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="365" mass="39697" checksum="88BA0F8FC909E4EB" modified="2016-02-17" version="1">MIKISGVAAVAAIVGLGGCAFAPGQYISPAQFARSDLAKDGHIQMVAITPDYLSAQQRVETSIPIELMAYQPEAYRIGRGDTLYITIWDHPELTSPAGTQQQTAANGRLVRPDGTLFYPYVGMIRAEGLTIEELRSQITSRISHYVQSPQVDVSIIDYGSQRVTLQGAFVKTERQPITATPLTLAQAIGAATVDPIRADLAGFVLTREGRQYHLDLDELNRGGSVAKDIYLKAGDHLYMPYNDRKEVYVVGEVVRPQAMTFKTTDLTLTQALGRAGGLNPLTAKGDSVYVIRGVETQDKQPATIFHLSAKSPAAFALGSRFHVRAGDVVFVGPAGVTRWNRFVNQLLPLSNIVNNAANTQDLLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGS7</accession>
    <name>A0A0S2DGS7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">ABC transporter, ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_10650</name>
        <name evidence="5" type="ORF">GLE_2105</name>
    </gene>
    <organism evidence="5 7">
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW26058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947284.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2105"/>
    <dbReference type="EnsemblBacteria" id="ALN57455">
        <property type="protein sequence ID" value="ALN57455"/>
        <property type="gene ID" value="GLE_2105"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2105"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2069"/>
    <dbReference type="OMA" id="GETVFFY"/>
    <dbReference type="OrthoDB" id="1926714at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW26058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="315" mass="35694" checksum="B69AE86FEB54F28E" modified="2016-02-17" version="1">MIHSLEVHDVRKSYGDFQAVKGMSFKVRQGSCFGILGPNGAGKTTLLGMIEGIVPISSGSINLLGMDVATQIRKIQPRIGVQLQQNNYFQFLSVAQLLKFYQQLRRAGGPPRKGQSIEWLLQRLGLSDKLKFKVDELSGGQKQRLSIAIALLEDPDVIFLDEPTSALDPHSRHLTWEFIEQLKQDPNKTVILTTHYMEEAERLCDEIMIMNDGRVIAQGNPAELVSGMQARQAIQFQFAKGQFKLEYVQDLADATDLHWDDQTDRLRVTTREVAQTMRSILERSQSQRIDVINFDIDRPSLEDVFLSHTAKDPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGV2</accession>
    <name>A0A0S2DGV2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin reductase</fullName>
            <ecNumber evidence="3">1.8.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">trxB</name>
        <name evidence="7" type="ORF">BV903_01920</name>
        <name evidence="8" type="ORF">FE772_11620</name>
        <name evidence="6" type="ORF">GLE_2315</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">C3</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:20345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="4">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.9" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000004">
        <property type="protein sequence ID" value="OPD65550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947444.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2315"/>
    <dbReference type="EnsemblBacteria" id="ALN57664">
        <property type="protein sequence ID" value="ALN57664"/>
        <property type="gene ID" value="GLE_2315"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65550">
        <property type="protein sequence ID" value="OPD65550"/>
        <property type="gene ID" value="BV903_01920"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2315"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2280"/>
    <dbReference type="OMA" id="VDNFPGY"/>
    <dbReference type="OrthoDB" id="692968at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019430">
        <property type="term" value="P:removal of superoxide radicals"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008255">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005982">
        <property type="entry name" value="Thioredox_Rdtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01292">
        <property type="entry name" value="TRX_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00573">
        <property type="entry name" value="PYRIDINE_REDOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 3" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="5">
        <location>
            <begin position="8"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD65550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW26221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="317" mass="33941" checksum="7CF173209F84FE0F" modified="2016-02-17" version="1">MSPTKHSRVVILGSGPAGWTAAVYAARANLKPLVITGLQQGGQLMTTTEVDNWPGDAHGLMGPDLMARMQAHAERFDTEVQFDHIHTADLSKRPFRLIGDSGEYTADALIIATGATAKYLGLPSEDEYKGRGVSACATCDGFFYKDQDVAVVGGGNTAVEEALYLSNIARKVYLVHRRDTLRAEKIMQDKLQAKIQAGKIEPVWHHTVDEVTGNDAGVTGLKLKSVLDGSSRELAIHGLFVAIGHTPNTSLFDGQLEMKNGYLTIRTGLDGNATQTSVDGVFAAGDVADQVYRQAITSAGFGCMAALDAEKFLDKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGW0</accession>
    <name>A0A0S2DGW0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2470"/>
    <dbReference type="EnsemblBacteria" id="ALN57819">
        <property type="protein sequence ID" value="ALN57819"/>
        <property type="gene ID" value="GLE_2470"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2470"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2432"/>
    <dbReference type="OMA" id="YLRMHGR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002763">
        <property type="entry name" value="DUF72"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036520">
        <property type="entry name" value="UPF0759_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30348">
        <property type="entry name" value="PTHR30348"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01904">
        <property type="entry name" value="DUF72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117396">
        <property type="entry name" value="SSF117396"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="282" mass="30845" checksum="DFB394CA53310718" modified="2016-02-17" version="1">MQISDSRRPAPRNHEERDSAERAADRRDAPPASAGRIRIGCAGWSLPAAQRARFGAGDSVLSAYATGLDAVEINSSFYRPHRRATYERWAASVPARFRFSVKLPRAITHEAGLRGAGPMLDEFLAQAGGLGDKLGVLLVQLPPSLRFDAAAAARFFAMLARRSEVPAVCEPRHRSWFHPRADALLQRYDVQRAGVDPAAPLAAAAEPSPHGRVRYWRWHGSPRTYYSEYGEDRLRVMAEAVRARAGESGAQTWCVFDNTAAGHAVADALRLRELCAGFASVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-06-17" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGZ3</accession>
    <name>A0A0S2DGZ3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2363</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57712">
        <property type="protein sequence ID" value="ALN57712"/>
        <property type="gene ID" value="GLE_2363"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2363"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2324"/>
    <dbReference type="OMA" id="HCECRIL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="61" mass="6559" checksum="234BA730F82C314D" modified="2016-02-17" version="1">MTMPDRGGTFDSFECAIHALAPRCAHCDCRIVGHGVEHAGRYYCCAHCAGHAGVQGIRDRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH66</accession>
    <name>A0A0S2DH66_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gluconate 2-dehydrogenase subunit 3 family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Tat (Twin-arginine translocation) pathway signal sequence</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_13075</name>
        <name evidence="1" type="ORF">GLE_2605</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947671.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2605"/>
    <dbReference type="EnsemblBacteria" id="ALN57953">
        <property type="protein sequence ID" value="ALN57953"/>
        <property type="gene ID" value="GLE_2605"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2605"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2565"/>
    <dbReference type="OMA" id="GDKAWAT"/>
    <dbReference type="OrthoDB" id="1574258at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027056">
        <property type="entry name" value="Gluconate_2DH_su3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13618">
        <property type="entry name" value="Gluconate_2-dh3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="191" mass="20125" checksum="DF55865E74225D1E" modified="2016-02-17" version="1">MERRELLKMIAAATGAAMIGVPAFVYGQAPAPSGNSAFSADEVAKLDEIADTILPRTKTPGAKDAGVGAFMATFVTDCYTPEYQAIFHAGLVEIDKRAGGRFVSLSPQARTELLRVLDGEAGRLINSMAVATGGATANAVKPHYFTMIKQLTLFGFFTSKVGATQALRYVAVPGRYDGAAVYEPGTPAWAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHC2</accession>
    <name>A0A0S2DHC2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57790">
        <property type="protein sequence ID" value="ALN57790"/>
        <property type="gene ID" value="GLE_2441"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2441"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2404"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="63" mass="6779" checksum="38D2C61C9D790306" modified="2016-02-17" version="1">MACAQATETRSQHFTGRPRSVRLARNAQCVAFASQNASRARRFARSAKLGALSASQKARAQGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHJ1</accession>
    <name>A0A0S2DHJ1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Neutral metalloproteinase</fullName>
            <ecNumber evidence="9">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">nprV</name>
        <name evidence="11" type="ORF">GLE_2743</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Extracellular zinc metalloprotease.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the peptidase M4 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2743"/>
    <dbReference type="EnsemblBacteria" id="ALN58091">
        <property type="protein sequence ID" value="ALN58091"/>
        <property type="gene ID" value="GLE_2743"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2743"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2701"/>
    <dbReference type="OMA" id="DTMGHEM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011096">
        <property type="entry name" value="FTP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002884">
        <property type="entry name" value="P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025711">
        <property type="entry name" value="PepSY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023612">
        <property type="entry name" value="Peptidase_M4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001570">
        <property type="entry name" value="Peptidase_M4_C_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013856">
        <property type="entry name" value="Peptidase_M4_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07504">
        <property type="entry name" value="FTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01483">
        <property type="entry name" value="P_proprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03413">
        <property type="entry name" value="PepSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01447">
        <property type="entry name" value="Peptidase_M4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02868">
        <property type="entry name" value="Peptidase_M4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00730">
        <property type="entry name" value="THERMOLYSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51829">
        <property type="entry name" value="P_HOMO_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3 9 11" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023153032" description="Neutral metalloproteinase" evidence="9">
        <location>
            <begin position="24"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="P/Homo B" evidence="10">
        <location>
            <begin position="515"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="357"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR623612-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN58091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="633" mass="67174" checksum="F8DA91C1A144368E" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHP2</accession>
    <name>A0A0S2DHP2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Segregation and condensation protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">scpB</name>
        <name evidence="5" type="ORF">GLE_2791</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2791"/>
    <dbReference type="EnsemblBacteria" id="ALN58139">
        <property type="protein sequence ID" value="ALN58139"/>
        <property type="gene ID" value="GLE_2791"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2791"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2747"/>
    <dbReference type="OMA" id="ERDWIRV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051304">
        <property type="term" value="P:chromosome separation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005234">
        <property type="entry name" value="ScpB_csome_segregation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34298">
        <property type="entry name" value="PTHR34298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04079">
        <property type="entry name" value="SMC_ScpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00281">
        <property type="entry name" value="TIGR00281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="181"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="236"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="288"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="335"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="350" mass="36998" checksum="66657E7C9C75595B" modified="2016-02-17" version="1">MDQPLITRIVEAALLAANQPLSLAQLHALFPEDQPPPPDSVESALQALREGCAERGVELVEVASGFRFQVKADVHAWVARLWTERQTRYTRATLETLALIAYRQPITRGEIEQVRGVAVSSNIIKALEEREWIRVVGHRDVPGKPALFGTTKAFLDYFGLKRLDDLPPLSELKEIGELEPQLPLDGAPIPAGVSADGDSAAAAGDGADAAANDEAGASADADDEADDKAEAEADAAAGDEADASAESESESEPGDEAQAPAADSQARDGEPAAEAEPESQSADAPAAATDEDPEHTVLSDDPEAAPGERAADANEHEQSEPAVETTTDALNEHVPQLEAESEDDRPEQDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHU3</accession>
    <name>A0A0S2DHU3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2671</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58019">
        <property type="protein sequence ID" value="ALN58019"/>
        <property type="gene ID" value="GLE_2671"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2671"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2630"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="167" mass="18427" checksum="3856211236B5AE0B" modified="2016-02-17" version="1">MPECLHGASLTRGPGGAHSVEGERGRAFRPDAFRSGAVWGERQERKASGLKPLPQQLCIAWARTGFCGRAFRPDAFRSGAVWGRAIRAKVIGAEAPPTTAACKRKRSGRSSCFRTLRTRCLPNRSTRRRGLGRKSCPSRQIAESACTSSEIRQRHEVRRRPTVPLCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIE8</accession>
    <name>A0A0S2DIE8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Response regulator transcription factor</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Two component transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_14295</name>
        <name evidence="5" type="ORF">GLE_2862</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947869.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2862"/>
    <dbReference type="EnsemblBacteria" id="ALN58210">
        <property type="protein sequence ID" value="ALN58210"/>
        <property type="gene ID" value="GLE_2862"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2862"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2824"/>
    <dbReference type="OMA" id="QHENKEY"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="146"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW26653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="220" mass="23522" checksum="C50033F60CB2C5D2" modified="2016-02-17" version="1">MPTLLIADDHPLFRAALRQAAADAVPETVVREAGTLDDALAALEAEPGIDLVLLDLHMPGNHGLAGLAAIRAQFPGTAVAVVSANDDPRVVRRALDHGAAGYLPKSSGLDELRDAIRAVLACEQWLPASLRAAVARTHSERGDADLAARLASLSPQQFRVLSLVAQGLLNKQIADRLEVQERTVKAHLSAIFDRLGVRNRTQAGVVLRELELADPARRID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIF1</accession>
    <name>A0A0S2DIF1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Helix-turn-helix domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_14510</name>
        <name evidence="3" type="ORF">GLE_2908</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947900.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2908"/>
    <dbReference type="EnsemblBacteria" id="ALN58256">
        <property type="protein sequence ID" value="ALN58256"/>
        <property type="gene ID" value="GLE_2908"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2908"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2870"/>
    <dbReference type="OMA" id="ADCWTQV"/>
    <dbReference type="OrthoDB" id="2071222at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025194">
        <property type="entry name" value="DUF4115"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13464">
        <property type="entry name" value="DUF4115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="19"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="274" mass="28780" checksum="B30DC87CF7C39295" modified="2016-02-17" version="1">MMQSNEFAPEVGGSCGARLKQAREAAGLSIEDVAAKLKMPARAIQSLEQDDFARIGAPVFVRGQLRSYARLLGVDLEEQLVASPIASTAPSELVSHTHTPRYRRVFEQTTRRAVYIVMTAAIAVPIWIATRHPAGNSAVQSLDMAALPAGADAAQSARPASDPPQRTPVIASIGPSLPQAAPAPTAAKSLTFKFSGDSWVQIVGNDGRKLEEGILGAGQERSYAPGEVANVRLGNTSAVEVLNAGQPVDLTPFSRANVARFTLSSDGSLAPVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIM6</accession>
    <name>A0A0S2DIM6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3018</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3018"/>
    <dbReference type="EnsemblBacteria" id="ALN58366">
        <property type="protein sequence ID" value="ALN58366"/>
        <property type="gene ID" value="GLE_3018"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3018"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2979"/>
    <dbReference type="OMA" id="WALQPAG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="223" mass="24132" checksum="8D6668087BA67CDA" modified="2016-02-17" version="1">MMNLPVAPPPTTPTLGQRLRLYLYSNRNIAGCALGLVGLGLLFAGVIATGWPLIVLGLYGVGALAWPRDRLGERVAEAELPVEALIEHLDRLVGEVAKRVPAEALASLRNIQETLGELLPRLHQLRGSGALSASAAFAVQESLRRYLPDMLGGYLKLPPVFARTQPLKDGRTAAQTLSQQLDLLDQSLQRISREAFAGDAESLLLSERFLKEKFDAAAAFELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIM8</accession>
    <name>A0A0S2DIM8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dCTP deaminase</fullName>
            <ecNumber evidence="3">3.5.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Deoxycytidine triphosphate deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">dcd</name>
        <name evidence="6" type="ORF">BV903_25050</name>
        <name evidence="8" type="ORF">D9T17_12330</name>
        <name evidence="7" type="ORF">FE772_15695</name>
        <name evidence="5" type="ORF">GLE_3156</name>
    </gene>
    <organism evidence="5 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 9">C3</strain>
        </source>
    </reference>
    <reference evidence="6 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">OH11</strain>
        </source>
    </reference>
    <reference evidence="7 12" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the deamination of dCTP to dUTP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>dCTP + H(+) + H2O = dUTP + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:22680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
            <dbReference type="ChEBI" id="CHEBI:61555"/>
            <dbReference type="EC" id="3.5.4.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the dCTP deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.13" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000104">
        <property type="protein sequence ID" value="OPD61166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000030">
        <property type="protein sequence ID" value="ROU06779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948085.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000030.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3156"/>
    <dbReference type="EnsemblBacteria" id="ALN58502">
        <property type="protein sequence ID" value="ALN58502"/>
        <property type="gene ID" value="GLE_3156"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61166">
        <property type="protein sequence ID" value="OPD61166"/>
        <property type="gene ID" value="BV903_25050"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3156"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3113"/>
    <dbReference type="OMA" id="FENHRYP"/>
    <dbReference type="OrthoDB" id="1598407at2"/>
    <dbReference type="UniPathway" id="UPA00610">
        <property type="reaction ID" value="UER00665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008829">
        <property type="term" value="F:dCTP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006226">
        <property type="term" value="P:dUMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006229">
        <property type="term" value="P:dUTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00146">
        <property type="entry name" value="dCTP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011962">
        <property type="entry name" value="dCTP_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="SSF51283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02274">
        <property type="entry name" value="dCTP_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="dUTPase" evidence="4">
        <location>
            <begin position="83"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="113"/>
            <end position="118"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="137"/>
            <end position="139"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD61166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW26872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROU06779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="190" mass="21324" checksum="F15B73EC4651D085" modified="2016-02-17" version="1">MSIKSDRWIRRMSEQPGGMIEPFEPGQVKQSADGQRIVSYGTSSYGYDVRCSREFKVFTNINSTIVDPKHFDSGSFVDVESDVCIIPPNSFALARTVEYFRIPRDVLVVCLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTPLPARIYANEGVAQMLFFQSDEVCDTSYRDRGGKYQGQTGVTLPRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIP6</accession>
    <name>A0A0S2DIP6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TetR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">TetR/AcrR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_02790</name>
        <name evidence="5" type="ORF">FE772_14630</name>
        <name evidence="3" type="ORF">GLE_2933</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000005">
        <property type="protein sequence ID" value="OPD65462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947922.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000005.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58281">
        <property type="protein sequence ID" value="ALN58281"/>
        <property type="gene ID" value="GLE_2933"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65462">
        <property type="protein sequence ID" value="OPD65462"/>
        <property type="gene ID" value="BV903_02790"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2933"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2895"/>
    <dbReference type="OMA" id="VIREYHT"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="11"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD65462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="205" mass="22087" checksum="5B00C57C546C2FD4" modified="2016-02-17" version="1">MSSLTATNKGAATREAILEQAYSIACSAGLEGLSIGPLAAAVGMSKSGVFAHFGSREDLQLAVLDKASERFIGYVLLPALKCPRGLQRLRGIVEAWFDWSRHTDGGCVLLAAVNEYDDRPGSLRDSVVDQQKRWHQELGRAVQLAIDTGELESDTDTAQLAFEIYGLALVVHHDAGLFGFDAALVRGLRAYERLIRSYAAAPVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIT9</accession>
    <name>A0A0S2DIT9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Carbonic anhydrase</fullName>
            <ecNumber evidence="3 6">4.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Carbonate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_15105</name>
        <name evidence="7" type="ORF">GLE_3022</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Reversible hydration of carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>H(+) + hydrogencarbonate = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="3 6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947988.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3022"/>
    <dbReference type="EnsemblBacteria" id="ALN58370">
        <property type="protein sequence ID" value="ALN58370"/>
        <property type="gene ID" value="GLE_3022"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3022"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2983"/>
    <dbReference type="OMA" id="WHYIIET"/>
    <dbReference type="OrthoDB" id="1841447at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015976">
        <property type="term" value="P:carbon utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00884">
        <property type="entry name" value="beta_CA_cladeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045066">
        <property type="entry name" value="Beta_CA_cladeB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015892">
        <property type="entry name" value="Carbonic_anhydrase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002">
        <property type="entry name" value="PTHR11002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="SSF53056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00704">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00705">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW26778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="226" mass="24641" checksum="75EBAE554AF3227E" modified="2016-02-17" version="1">MDRLIQGFNRFRREVFPHQRELFHKLAQGQQPHTMFITCADSRVMPELILCAQPGELFVYRNVGNIVPPYAQHVSSVVAAIEYAVKVLKVRHIVICGHSDCGAMKALQDPERIASMPSLSAWLRHADVARHVVAENGPTLEGEVGLRCLTEENVVGQLEHLRTLPAVAAAIANGSLAIHGWIYDIAHAELRAFDPARGGFVAVLPGSESAPDATPLARFALTGTDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIX5</accession>
    <name>A0A0S2DIX5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-binding protein Uup</fullName>
            <ecNumber evidence="5">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">uup</name>
        <name evidence="9" type="ORF">FE772_15530</name>
        <name evidence="8" type="ORF">GLE_3120</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="5">Associates with ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948058.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3120"/>
    <dbReference type="EnsemblBacteria" id="ALN58467">
        <property type="protein sequence ID" value="ALN58467"/>
        <property type="gene ID" value="GLE_3120"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3120"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3077"/>
    <dbReference type="OMA" id="AQADKMR"/>
    <dbReference type="OrthoDB" id="1112046at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00848">
        <property type="entry name" value="Uup"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032524">
        <property type="entry name" value="ABC_tran_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043686">
        <property type="entry name" value="Uup"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16326">
        <property type="entry name" value="ABC_tran_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="4"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="315"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <begin position="347"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW26846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="627" mass="69340" checksum="C10FE336F3C522B5" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ05</accession>
    <name>A0A0S2DJ05_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pseudouridine synthase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">RNA pseudouridine synthase A</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rluA</name>
        <name evidence="4" type="ORF">FE772_15585</name>
        <name evidence="3" type="ORF">GLE_3133</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58480">
        <property type="protein sequence ID" value="ALN58480"/>
        <property type="gene ID" value="GLE_3133"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3133"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3091"/>
    <dbReference type="OMA" id="HYFREVP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="2">
        <location>
            <begin position="114"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="314" mass="35421" checksum="A029A225613E95F9" modified="2016-02-17" version="1">MPIPPPDAPFDLGLPQASAPHASAPHAPAPSRLQLPPGPWSNLLDGLCARFPAIGRERWWERFARGRVLDARDGRALDAAEPYKVGLEILYFREVEREPRIPFEERIVHADERLLVVDKPHFLPVAPAGRFVAETLLARLQRRYREPDLAPLHRLDAATAGLVLFSRERASRGAYQALFRERRIDKRYLALAPPLPALAFPLLRRSRIEPGEPFFLMREADGAANSETTVEVVSRGPRAWTYALHPVTGRKHQLRVHMAALGAPILGDRFYPLQARSEADDEDFSQPLKLLAQSLRFVDPLDGRERWFESGLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ08</accession>
    <name>A0A0S2DJ08_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_24565</name>
        <name evidence="5" type="ORF">D9T17_11860</name>
        <name evidence="4" type="ORF">FE772_16180</name>
        <name evidence="2" type="ORF">GLE_3269</name>
    </gene>
    <organism evidence="2 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">C3</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 9" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000096">
        <property type="protein sequence ID" value="OPD61250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000029">
        <property type="protein sequence ID" value="ROU06803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948165.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000029.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58615">
        <property type="protein sequence ID" value="ALN58615"/>
        <property type="gene ID" value="GLE_3269"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61250">
        <property type="protein sequence ID" value="OPD61250"/>
        <property type="gene ID" value="BV903_24565"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3269"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3222"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594827" evidence="1">
        <location>
            <begin position="26"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU06803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="66" mass="7362" checksum="2B4354C0CF6A46E3" modified="2016-02-17" version="1">MFKRNRIFAAAAFCFGLAFSFGAFAQQDCQACTDACYEQYEQCNSDGYPFCKQNLRACTKACGCQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ13</accession>
    <name>A0A0S2DJ13_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Bifunctional NAD(P)H-hydrate repair enzyme</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Nicotinamide nucleotide repair protein</fullName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="16">ADP-dependent (S)-NAD(P)H-hydrate dehydratase</fullName>
                <ecNumber evidence="16">4.2.1.136</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="16">ADP-dependent NAD(P)HX dehydratase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="16">NAD(P)H-hydrate epimerase</fullName>
                <ecNumber evidence="16">5.1.99.6</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="15" type="primary">nnrE</name>
        <name evidence="14" type="synonym">nnrD</name>
        <name evidence="18" type="ORF">GLE_3170</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 16">Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.</text>
    </comment>
    <comment type="function">
        <text evidence="14">Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.</text>
    </comment>
    <comment type="function">
        <text evidence="15">Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15 16">
            <text>(6R)-NADHX = (6S)-NADHX</text>
            <dbReference type="Rhea" id="RHEA:32215"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:64075"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 15 16">
            <text>(6R)-NADPHX = (6S)-NADPHX</text>
            <dbReference type="Rhea" id="RHEA:32227"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:64077"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 14 16">
            <text>(6S)-NADHX + ADP = AMP + H(+) + NADH + phosphate</text>
            <dbReference type="Rhea" id="RHEA:32223"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.136"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 14 16">
            <text>(6S)-NADPHX + ADP = AMP + H(+) + NADPH + phosphate</text>
            <dbReference type="Rhea" id="RHEA:32235"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.136"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15 16">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="15 16">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="14">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the NnrD/CARKD family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the NnrE/AIBP family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 16">In the C-terminal section; belongs to the NnrD/CARKD family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 16">In the N-terminal section; belongs to the NnrE/AIBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.136" evidence="16"/>
    <dbReference type="EC" id="5.1.99.6" evidence="16"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948094.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3170"/>
    <dbReference type="EnsemblBacteria" id="ALN58516">
        <property type="protein sequence ID" value="ALN58516"/>
        <property type="gene ID" value="GLE_3170"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3170"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3125"/>
    <dbReference type="OMA" id="HNGGDAL"/>
    <dbReference type="OrthoDB" id="1748633at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052855">
        <property type="term" value="F:ADP-dependent NAD(P)H-hydrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052856">
        <property type="term" value="F:NADHX epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052857">
        <property type="term" value="F:NADPHX epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046496">
        <property type="term" value="P:nicotinamide nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01171">
        <property type="entry name" value="YXKO-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01965">
        <property type="entry name" value="NADHX_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01966">
        <property type="entry name" value="NADHX_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017953">
        <property type="entry name" value="Carbohydrate_kinase_pred_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000631">
        <property type="entry name" value="CARKD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030677">
        <property type="entry name" value="Nnr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004443">
        <property type="entry name" value="YjeF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036652">
        <property type="entry name" value="YjeF_N_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01256">
        <property type="entry name" value="Carb_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03853">
        <property type="entry name" value="YjeF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017184">
        <property type="entry name" value="Nnr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64153">
        <property type="entry name" value="SSF64153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00196">
        <property type="entry name" value="yjeF_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00197">
        <property type="entry name" value="yjeF_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01049">
        <property type="entry name" value="YJEF_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01050">
        <property type="entry name" value="YJEF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51383">
        <property type="entry name" value="YJEF_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51385">
        <property type="entry name" value="YJEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 15 16" id="KW-0413">Isomerase</keyword>
    <keyword evidence="18" id="KW-0418">Kinase</keyword>
    <keyword evidence="12 14 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="15 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 14 16" id="KW-0520">NAD</keyword>
    <keyword evidence="9 14 16" id="KW-0521">NADP</keyword>
    <keyword evidence="7 14 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15 16" id="KW-0630">Potassium</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="18" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="YjeF N-terminal" evidence="17">
        <location>
            <begin position="29"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="NADPHX" evidence="15">
        <location>
            <begin position="76"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="NADPHX" evidence="15">
        <location>
            <begin position="143"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="381"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="418"/>
            <end position="422"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="447"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="448"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR017184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ALN58516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="511" mass="52695" checksum="10AC6ECF36EC64B1" modified="2016-02-17" version="1">MSRSAETEGRRAGARAATAPCPLYDAAALRAAERGAAAASGDAFELMRRAGEAAWREWLDRWSQAYSLLVVCGPGNNGGDGYVMATHALRNGRKVAVVRLRDHAPRSELARRAADGYRDAGGATLEFDGALPPAEAIVDALFGIGLSRAPDAAAGALIEAINGHGAPVFALDVPSGVDADRGAVAGRAVVADCTLEFIARKRGLRTGAALDHVGEPVLASLGVDMSEHAAYPVAEWLRAPDLGRWLRPRRRDSHKGRNGRVLCIGGDHGHGGALVLCAQAALRSGAGLVDAATRADHVAPLLARLPEAMPRAVESSDDLRAALAAADVIAIGPGLGTQEWGALLFAAALASDKPLLLDADALNLLAAQPRALPADCILTPHPGEAARLLGSDTARVQADRDAAVRALVERYRCAVVLKGAGTLVHAPGQGVRVIGAGNPGMAVGGMGDVLSGAIAALRAQGLDAFDAASCGALLHSTAGDRAARDDGERGLLPSDLMPWLRRCANPRADER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJA1</accession>
    <name>A0A0S2DJA1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Alanine--tRNA ligase</fullName>
            <ecNumber evidence="11">6.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Alanyl-tRNA synthetase</fullName>
            <shortName evidence="11">AlaRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 13" type="primary">alaS</name>
        <name evidence="13" type="ORF">GLE_3200</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala)</text>
            <dbReference type="Rhea" id="RHEA:12540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:9923"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78497"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.7" evidence="11"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3200"/>
    <dbReference type="EnsemblBacteria" id="ALN58546">
        <property type="protein sequence ID" value="ALN58546"/>
        <property type="gene ID" value="GLE_3200"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3200"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3156"/>
    <dbReference type="OMA" id="YHHTMFE"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006419">
        <property type="term" value="P:alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00036_B">
        <property type="entry name" value="Ala_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002318">
        <property type="entry name" value="Ala-tRNA-lgiase_IIc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018162">
        <property type="entry name" value="Ala-tRNA-ligase_IIc_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023033">
        <property type="entry name" value="Ala_tRNA_ligase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00980">
        <property type="entry name" value="TRNASYNTHALA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101353">
        <property type="entry name" value="SSF101353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00344">
        <property type="entry name" value="alaS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11 13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 11 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 11" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="6 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II_ALA" evidence="12">
        <location>
            <begin position="1"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="537"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="541"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="639"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="643"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN58546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="849" mass="90910" checksum="82F521CC14291D4F" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJU3</accession>
    <name>A0A0S2DJU3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dTTP/UTP pyrophosphatase</fullName>
            <shortName evidence="3">dTTPase/UTPase</shortName>
            <ecNumber evidence="3">3.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Nucleoside triphosphate pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Nucleotide pyrophosphatase</fullName>
            <shortName evidence="3">Nucleotide PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">maf</name>
        <name evidence="4" type="ORF">GLE_3408</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + UTP = diphosphate + H(+) + UMP</text>
            <dbReference type="Rhea" id="RHEA:29395"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="EC" id="3.6.1.9"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>dTTP + H2O = diphosphate + dTMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28534"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37568"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="EC" id="3.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Maf family. YhdE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.9" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3408"/>
    <dbReference type="EnsemblBacteria" id="ALN58754">
        <property type="protein sequence ID" value="ALN58754"/>
        <property type="gene ID" value="GLE_3408"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3408"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3358"/>
    <dbReference type="OMA" id="RIDGDFY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036218">
        <property type="term" value="F:dTTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035529">
        <property type="term" value="F:NADH pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036221">
        <property type="term" value="F:UTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00555">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00528">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003697">
        <property type="entry name" value="Maf-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213">
        <property type="entry name" value="PTHR43213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02545">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006305">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00172">
        <property type="entry name" value="maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="14"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="193" mass="20566" checksum="5EA362AAAAC76D73" modified="2016-02-17" version="1">MLSHMLYLASQSPRRRELLGRLGLEFGLIDLDIPEQRQPGEPAADYVRRVAREKAGAGLLKVVANPSAAVLGADTEVVLDDEVFGKPRDPEDARAMLRRLSGRTHQVISAVSLVTPAREAQAVSVSEVSFAALDEGQIERYVAGGEPMGKAGGYAIQGGAEVFVSRLAGSYSGVMGLPLHETARLLREFGLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJW9</accession>
    <name>A0A0S2DJW9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_16695</name>
        <name evidence="2" type="ORF">GLE_3383</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948256.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58729">
        <property type="protein sequence ID" value="ALN58729"/>
        <property type="gene ID" value="GLE_3383"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3383"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3333"/>
    <dbReference type="OrthoDB" id="1843257at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="168" mass="18727" checksum="E986ECC5D70BC013" modified="2016-02-17" version="1">MTATVQRLRIGRTVFAYAADGAEHRAEATEIFIDERPLAHWLGIASDLGNADTDLDTRAPPALAERGRAAFLGLQPAHNPFGSGRLVLYRCHCGSDYCGTISCLLDIDDDHVVWRQVTREDDNGPMPGADPGENAGSSWLPPGAPLRFVFDRRQYRRELERHFQQRPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJY9</accession>
    <name>A0A0S2DJY9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidoglycan-binding LysM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3457</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3457"/>
    <dbReference type="EnsemblBacteria" id="ALN58802">
        <property type="protein sequence ID" value="ALN58802"/>
        <property type="gene ID" value="GLE_3457"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3457"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3405"/>
    <dbReference type="OMA" id="GVPAPKH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006860">
        <property type="entry name" value="FecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016930">
        <property type="entry name" value="UCP029644"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04773">
        <property type="entry name" value="FecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029644">
        <property type="entry name" value="UCP029644"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594864" evidence="1">
        <location>
            <begin position="47"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="49"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="567" mass="60622" checksum="2E216F95108141C1" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK90</accession>
    <name>A0A0S2DK90_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Threonine--tRNA ligase</fullName>
            <ecNumber evidence="12">6.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Threonyl-tRNA synthetase</fullName>
            <shortName evidence="12">ThrRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12 15" type="primary">thrS</name>
        <name evidence="16" type="ORF">BV903_16760</name>
        <name evidence="17" type="ORF">FE772_17585</name>
        <name evidence="15" type="ORF">GLE_3570</name>
    </gene>
    <organism evidence="15 18">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="15 18" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 18">C3</strain>
        </source>
    </reference>
    <reference evidence="16 19" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 19">B25</strain>
        </source>
    </reference>
    <reference evidence="17 20" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 20">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl-tRNA(Thr)</text>
            <dbReference type="Rhea" id="RHEA:24624"/>
            <dbReference type="Rhea" id="RHEA-COMP:9670"/>
            <dbReference type="Rhea" id="RHEA-COMP:9704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78534"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.3" evidence="12"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000045">
        <property type="protein sequence ID" value="OPD62751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948388.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3570"/>
    <dbReference type="EnsemblBacteria" id="ALN58914">
        <property type="protein sequence ID" value="ALN58914"/>
        <property type="gene ID" value="GLE_3570"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62751">
        <property type="protein sequence ID" value="OPD62751"/>
        <property type="gene ID" value="BV903_16760"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3570"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3514"/>
    <dbReference type="OMA" id="FYYDFAY"/>
    <dbReference type="OrthoDB" id="900765at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004829">
        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006435">
        <property type="term" value="P:threonyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00771">
        <property type="entry name" value="ThrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00184">
        <property type="entry name" value="Thr_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002320">
        <property type="entry name" value="Thr-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033728">
        <property type="entry name" value="ThrRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="PTHR11451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01047">
        <property type="entry name" value="TRNASYNTHTHR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00418">
        <property type="entry name" value="thrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12 15" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 12 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 12" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="7 12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="TGS" evidence="14">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="13">
        <location>
            <begin position="242"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Catalytic" evidence="12">
        <location>
            <begin position="242"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="384"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="510"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ALN58914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OPD62751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="QCW27175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="632" mass="72047" checksum="121E0236D82FB8AC" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKJ2</accession>
    <name>A0A0S2DKJ2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3712</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59056">
        <property type="protein sequence ID" value="ALN59056"/>
        <property type="gene ID" value="GLE_3712"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3712"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3657"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="67" mass="7933" checksum="B0EB2AFDF2FFD672" modified="2016-02-17" version="1">MRKIFRDLRGWARRRSPRRRAQRGLFRDLRSASRARRWRRGMPALARGLLRLFMPQAAAPALGRHAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKP1</accession>
    <name>A0A0S2DKP1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">UDP-N-acetylmuramoyl-L-alanine--L-glutamate ligase</fullName>
            <ecNumber evidence="9">6.3.2.53</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">UDP-N-acetylmuramoyl-L-alanyl-L-glutamate synthetase</fullName>
            <shortName evidence="9">UDP-MurNAc-L-Ala-L-Glu synthetase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">murD</name>
        <name evidence="9" type="synonym">murD2</name>
        <name evidence="11" type="ORF">GLE_3730</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Cell wall formation. Catalyzes the addition of L-glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-glutamate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:58816"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83898"/>
            <dbReference type="ChEBI" id="CHEBI:142725"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.53"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the MurCDEF family. MurD2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.53" evidence="9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948505.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3730"/>
    <dbReference type="EnsemblBacteria" id="ALN59074">
        <property type="protein sequence ID" value="ALN59074"/>
        <property type="gene ID" value="GLE_3730"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3730"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3675"/>
    <dbReference type="OMA" id="KGMHNVE"/>
    <dbReference type="OrthoDB" id="1093223at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008764">
        <property type="term" value="F:UDP-N-acetylmuramoylalanine-D-glutamate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00639">
        <property type="entry name" value="MurD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02208">
        <property type="entry name" value="MurD2_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005762">
        <property type="entry name" value="MurD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043687">
        <property type="entry name" value="MurD2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01087">
        <property type="entry name" value="murD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="5 9" id="KW-0133">Cell shape</keyword>
    <keyword evidence="8 9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="10">
        <location>
            <begin position="119"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="121"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN59074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="467" mass="49367" checksum="91AB2668F83C2C43" modified="2016-02-17" version="1">MRISQLDGKRVALWGWGREGRAAYRAIRARLPSLALTLFCSVDEAADARGLHDPWLTIETQASAERLGEFDWIVKSPGISPYRAEAVAAAEQGARFIGGTALWFGEHAAARDGGRTLCVTGTKGKSTTTSLLAHLLRAGGHRTALAGNIGLPLLEALDPPQPPEFWAIELSSYQTGDVALGGARPDVAVALNLYPEHLDWHGSQARYVDDKLRLLTDARPRIAVLNAADPVLSALSLPDSDIRWFGDATGWHLRGDALWRGEREVMDTASLPLPGRHNRGNLCAVLTAIEALGLDAEALAPAAASFKPLPNRLQPIGERDGIGYVNDSISTTPHATLAALDCYSGKRIALLVGGHDRGIDWHGFAQAMRTRAPLAIVTMGENGPRIHALIAAVAGEGGFALSAARDLAEAMAQARAALGAQGGVVLLSPGAPSFGPYRDYVARGRHFAELAGFDPDAISAIAGIGIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKS5</accession>
    <name>A0A0S2DKS5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein-export membrane protein SecF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 10" type="primary">secF</name>
        <name evidence="11" type="ORF">BV903_21575</name>
        <name evidence="12" type="ORF">FE772_17290</name>
        <name evidence="10" type="ORF">GLE_3512</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">C3</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SecD/SecF family. SecF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000071">
        <property type="protein sequence ID" value="OPD61868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948345.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000071.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3512"/>
    <dbReference type="EnsemblBacteria" id="ALN58856">
        <property type="protein sequence ID" value="ALN58856"/>
        <property type="gene ID" value="GLE_3512"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61868">
        <property type="protein sequence ID" value="OPD61868"/>
        <property type="gene ID" value="BV903_21575"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3512"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3456"/>
    <dbReference type="OMA" id="AFEWRMA"/>
    <dbReference type="OrthoDB" id="410730at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01464_B">
        <property type="entry name" value="SecF_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022645">
        <property type="entry name" value="SecD/SecF_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022646">
        <property type="entry name" value="SecD/SecF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005665">
        <property type="entry name" value="SecF_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07549">
        <property type="entry name" value="Sec_GG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02355">
        <property type="entry name" value="SecD_SecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01755">
        <property type="entry name" value="SECFTRNLCASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00916">
        <property type="entry name" value="2A0604s01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00966">
        <property type="entry name" value="3a0501s07"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="146"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="277"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN58856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OPD61868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW27129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="321" mass="34716" checksum="FAE51A001907F83A" modified="2016-02-17" version="1">MKIFPLTLLPNDANIDFMRLRWVSIAVAAIIMFVAIGAMGTRGFNYALDFTGGNLIEAQLDKALSLDAVRDKLAADGYDSAQVQTYGSGNQLLIRLQPREGESGDAATAHAAEAVTRAVTSNGGTAKIVRNEFVGPQVGKELALKGLYALVFVVVGFLIYIAFRFEWKFAVAAIITTLHDVIVVAGWFAVSGHEFDLTVLAGILSVMGYSINDTIVVFDRVRENFRTMRADPETVLNKSINQTLSRTIITSFVAFLTVLALYLYGGGSLRGMAESQMLGIIIGTLSSIFVACPLLTLGLLKVTKQDLMPKAKDEAALARRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKT0</accession>
    <name>A0A0S2DKT0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">CBS domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Magnesium and cobalt efflux protein CorC</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Magnesium/cobalt efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">corC</name>
        <name evidence="7" type="ORF">BV903_24315</name>
        <name evidence="8" type="ORF">FE772_17855</name>
        <name evidence="6" type="ORF">GLE_3629</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">C3</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000092">
        <property type="protein sequence ID" value="OPD61326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948428.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000092.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3629"/>
    <dbReference type="EnsemblBacteria" id="ALN58973">
        <property type="protein sequence ID" value="ALN58973"/>
        <property type="gene ID" value="GLE_3629"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61326">
        <property type="protein sequence ID" value="OPD61326"/>
        <property type="gene ID" value="BV903_24315"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3629"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3573"/>
    <dbReference type="OMA" id="QMISIKA"/>
    <dbReference type="OrthoDB" id="1155802at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0129">CBS domain</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="74"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="139"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD61326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW27217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="288" mass="31294" checksum="85607862BCE1DF2A" modified="2016-02-17" version="1">MSEDDSSTHSPEPHEKRRSWLDRISSALSGEPSSREDLVELLRDAQSDGLIAADTLHMMEGAIAVSDLTVGDVMIPRSQMVALPADAKFLDLMKLVVESGHSRFPVHGEDKDEILGILLAKDLLRGVVADNGPGTIHELLRPAVLIPESKRLDVLLREFRQSRNHMAIVIDEHGGVAGLLTIEDVLEQIVGDIDDEHDEAENTDALIAAQADGQYVVDALTPIDDFNERFGADFDDDEYDTIGGLVTAAIGHLPEAGEELTLGRFVFRVASADARRVHAFHVGVLGAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKW7</accession>
    <name>A0A0S2DKW7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 16">NAD(P) transhydrogenase subunit beta</fullName>
            <ecNumber evidence="7 16">7.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Nicotinamide nucleotide transhydrogenase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="primary">pntB</name>
        <name evidence="20" type="ORF">BV903_16060</name>
        <name evidence="21" type="ORF">FE772_18990</name>
        <name evidence="19" type="ORF">GLE_3864</name>
    </gene>
    <organism evidence="19 22">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="19 22" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 22">C3</strain>
        </source>
    </reference>
    <reference evidence="20 23" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 23">B25</strain>
        </source>
    </reference>
    <reference evidence="21 24" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 24">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 16">The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>H(+)(in) + NAD(+) + NADPH = H(+)(out) + NADH + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:47992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="7.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell inner membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 16">Belongs to the PNT beta subunit family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.1" evidence="7 16"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000042">
        <property type="protein sequence ID" value="OPD62906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057950231.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000042.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3864"/>
    <dbReference type="EnsemblBacteria" id="ALN59207">
        <property type="protein sequence ID" value="ALN59207"/>
        <property type="gene ID" value="GLE_3864"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62906">
        <property type="protein sequence ID" value="OPD62906"/>
        <property type="gene ID" value="BV903_16060"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3864"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3803"/>
    <dbReference type="OMA" id="KRGMSAG"/>
    <dbReference type="OrthoDB" id="788546at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008750">
        <property type="term" value="F:NAD(P)+ transhydrogenase (AB-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012136">
        <property type="entry name" value="NADH_DH_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034300">
        <property type="entry name" value="PNTB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02233">
        <property type="entry name" value="PNTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000204">
        <property type="entry name" value="PNTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 16" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="9 16" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15 16 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-0520">NAD</keyword>
    <keyword evidence="12 16" id="KW-0521">NADP</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 16" id="KW-1278">Translocase</keyword>
    <keyword evidence="11 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="133"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="PNTB" evidence="18">
        <location>
            <begin position="9"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00014581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR000204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ALN59207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="OPD62906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="QCW27413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="477" mass="49298" checksum="777941DADB67EA35" modified="2016-02-17" version="1">MDVLSTLVKASYLVAATLFLLGLQRMASPVTARSGIRWAGAGMIIATVATFFLPGLHNLGLIATAVLLGTAAAWVSGKKVAITDMPQMVALYNGMGGGSAAAIGAVELLRLSWKLPADPLQAQLEHGVVAMHTPSIALVLAMVGAAIGAVSLSGSVIAWAKLDGRLDKRVVFPGQQAFNALVALAMVVLGVAAVMTLNSGIIIAFILVALALGVLMTLPIGGADMPVVISLYNAFTGLAVAFEGYVLGNEALIIAGTMVGAAGMLLTRLMAKAMNRPISGVLFSNFGGGGQAQEIAGTQKPIEAGDVAAMMAFAERVVIVPGYGLAVAQAQHKIWELTQKLTERGVKVKFAIHPVAGRMPGHMNVLLAEAGVPYDMIADMDDINPEFATTDVSLVIGANDVVNPVAKTDPASPIYGMPILDVINSRNTIVIKRGKGTGFAGIENALFYADNTRMLYGDGAEMASALVSELKALDGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL02</accession>
    <name>A0A0S2DL02_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA-binding transcriptional regulator OxyR</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family/LysR substrate binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">oxyR</name>
        <name evidence="4" type="ORF">FE772_19100</name>
        <name evidence="3" type="ORF">GLE_3887</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948624.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3887"/>
    <dbReference type="EnsemblBacteria" id="ALN59230">
        <property type="protein sequence ID" value="ALN59230"/>
        <property type="gene ID" value="GLE_3887"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3887"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3826"/>
    <dbReference type="OMA" id="DQALDIC"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="316" mass="35224" checksum="DB6EE2CBB27E7608" modified="2016-02-17" version="1">MNLRDLKYLVALADHKHFGRAAAASFVSQPTLSTQIKKLEDELGVSLVERAPRRVMLTPVGRDIAERARKVIADVEQMSEIARRSQDPEAGTVRLGLFPTLGPYLLPHVVPNLRKRFPRLELLLVEEKTDQILARLRDGRLDAGLLALPIHDDQLHVEPLFDEPFILAVPQQHPMAARDSLDLHDLDDQHLLLLEEGHCLRDQALDVCRLAGADERDGFRATSLETLRQMVAAGVGITLLPTLAVQPPVPNSPDIRLLRFSGTPPHRQIGMLWRRSSAMSDFLLQLADELRKLPASLLQPPVAVAGGKRKPAREVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL35</accession>
    <name>A0A0S2DL35_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3929</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3929"/>
    <dbReference type="EnsemblBacteria" id="ALN59271">
        <property type="protein sequence ID" value="ALN59271"/>
        <property type="gene ID" value="GLE_3929"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3929"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3866"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="51" mass="6134" checksum="4FF3B7D03BF009A4" modified="2016-02-17" version="1">MYQPDNQAELADIINYQVIRGRRTSSELGKWWTARRSYRERPQPWPGWPAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL90</accession>
    <name>A0A0S2DL90_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_19575</name>
        <name evidence="3" type="ORF">GLE_3993</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948698.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3993"/>
    <dbReference type="EnsemblBacteria" id="ALN59335">
        <property type="protein sequence ID" value="ALN59335"/>
        <property type="gene ID" value="GLE_3993"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3993"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3930"/>
    <dbReference type="OMA" id="RTMANYL"/>
    <dbReference type="OrthoDB" id="1592248at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726580" evidence="2">
        <location>
            <begin position="23"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="307" mass="31953" checksum="8688D253E7CB3216" modified="2016-02-17" version="1">MTELLTSVVLLGIAALSAGAEAAPKRQEIPLYLSATRALVMVRIGSHPPFPAVFDTGTNGNLVDLGLARSLGLPNTGPSPSVDGSTGKPVPGHDTFIKDARLGGVAIADARATALAYDQPDEIGIFGPNSFPEHFVEMDGPGSRLVLTPRSDDNAPAGTALPYQADRLPAVVLDFGALRLPAKLDSGNDSALILPMRYKDQVALQAEPVRIGYAISAAGRQPIFSARLQGSLCVGPLRLEHPEVRFMEGGTANIGLGILRRLRVVYDDTGKRAWILPNPASPSDAPGAACPDSGGGGREPGSDAARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLD7</accession>
    <name>A0A0S2DLD7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rluD</name>
        <name evidence="6" type="ORF">BV903_18425</name>
        <name evidence="7" type="ORF">FE772_20125</name>
        <name evidence="5" type="ORF">GLE_4104</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for synthesis of pseudouridine from uracil.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000050">
        <property type="protein sequence ID" value="OPD62453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948786.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000050.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4104"/>
    <dbReference type="EnsemblBacteria" id="ALN59446">
        <property type="protein sequence ID" value="ALN59446"/>
        <property type="gene ID" value="GLE_4104"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62453">
        <property type="protein sequence ID" value="OPD62453"/>
        <property type="gene ID" value="BV903_18425"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4104"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4046"/>
    <dbReference type="OMA" id="AHPSPGW"/>
    <dbReference type="OrthoDB" id="1714699at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="4">
        <location>
            <begin position="93"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR606225-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD62453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW27601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="324" mass="35248" checksum="D814E941F32FF623" modified="2016-02-17" version="1">MTDSRQTLTATVPDAAAGRRFDAVLAELFPDYSRSRLAAWIKSGDARLNGREARPRDPVQGGEAVELNVVLDTQTHAVAEDIALDVLYEDAEVIVLDKPAGLVVHPGAGNPAGTLVNALLHRDPSLAALPRAGIVHRLDKDTSGVMVVARTLPAHTSLVDQLSAREVHRQYLAVVVGALVSGGTANAAIDRHPRDRLRMAVREDGREAVTHFRLRERFRAHTLLECRLETGRTHQIRVHMQHLKHPIVGDPLYGGPLKLPKGASDSLVETLRGFKRQALHAETLEFVHPISGEPVRCTAPVPADMLQLVAELREDSRAAAEAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLH9</accession>
    <name>A0A0S2DLH9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Wall associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_19795</name>
        <name evidence="1" type="ORF">GLE_4036</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4036"/>
    <dbReference type="EnsemblBacteria" id="ALN59378">
        <property type="protein sequence ID" value="ALN59378"/>
        <property type="gene ID" value="GLE_4036"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4036"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3978"/>
    <dbReference type="OMA" id="YVECNAG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031325">
        <property type="entry name" value="RHS_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05593">
        <property type="entry name" value="RHS_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="720" mass="78353" checksum="45B8895C56380E5D" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLL3</accession>
    <name>A0A0S2DLL3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Riboflavin biosynthesis protein RibD</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="10">Diaminohydroxyphosphoribosylaminopyrimidine deaminase</fullName>
                <shortName evidence="10">DRAP deaminase</shortName>
                <ecNumber evidence="10">3.5.4.26</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="10">Riboflavin-specific deaminase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="10">5-amino-6-(5-phosphoribosylamino)uracil reductase</fullName>
                <ecNumber evidence="10">1.1.1.193</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="10">HTP reductase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="15" type="primary">ribD</name>
        <name evidence="15" type="ORF">GLE_4156</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H(+) + H2O = 5-amino-6-(5-phospho-D-ribosylamino)uracil + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:21868"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58453"/>
            <dbReference type="ChEBI" id="CHEBI:58614"/>
            <dbReference type="EC" id="3.5.4.26"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5-amino-6-(5-phospho-D-ribitylamino)uracil + NADP(+) = 5-amino-6-(5-phospho-D-ribosylamino)uracil + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17845"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58421"/>
            <dbReference type="ChEBI" id="CHEBI:58453"/>
            <dbReference type="EC" id="1.1.1.193"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10 13">Binds 1 zinc ion.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 10">In the C-terminal section; belongs to the HTP reductase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.26" evidence="10"/>
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    <sequence length="1371" mass="148828" checksum="623C789CE3AADD2E" modified="2016-02-17" version="1"> </sequence>
</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="78" mass="8542" checksum="EEF2C463942D9422" modified="2016-02-17" version="1">MSKLRGNAPAGEEVWTTRGELRNPADRSDQSGQWALERTEEAAPAASVEKPVTMPARLRKVPLESQAQDVGNSPRRTT</sequence>
</entry>
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    <accession>A0A0S2DM52</accession>
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        <submittedName>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
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        <property type="entry name" value="KaiC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06745">
        <property type="entry name" value="ATPase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51146">
        <property type="entry name" value="KAIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KaiC" evidence="2">
        <location>
            <begin position="175"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="420" mass="45909" checksum="9DE97B663EA38D23" modified="2016-02-17" version="1">MLRYQQQFGFFDDTAINRSVRFVNLGEEIQAGSLDRVLQRIEAEVEKSGPALVFVDSFRSVMLAGVSAGDRIADLQHFVQRLGVAMTGWQATTFLIGEYFNDSEANPVFTVADGLIWLRQSVQRNSMVRKMEVLKMRGQATLPGLHTFRIGPEGIEVFAPALIAAAMDRGAGTKPRLGMGDATLDEMLGGGLPQGYSLLVAGPSGSGKSILASAFLSEGDRVGERGVIAVFEQQPNRGRNERLIELIETGRVGLVDSRASDLSIDEVILLLLKEVERLGATRVVIDSLSAFELALAPTFREDFRQSLARLVSAMAKAGVSLLMTSELEDRYTDLRFSPYGTAFLTDAIIVQRYVEIDSRLLRVIAVVKVRASAHSNDLRLYEIDSDGLRIAGRLDDREGLLGGRPTRKAGTHGTCDDDRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMA9</accession>
    <name>A0A0S2DMA9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TIGR02680 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_20945</name>
        <name evidence="3" type="ORF">GLE_4278</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948926.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4278"/>
    <dbReference type="EnsemblBacteria" id="ALN59619">
        <property type="protein sequence ID" value="ALN59619"/>
        <property type="gene ID" value="GLE_4278"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4278"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4217"/>
    <dbReference type="OMA" id="MYIPLFA"/>
    <dbReference type="OrthoDB" id="159395at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013496">
        <property type="entry name" value="CHP02680"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02680">
        <property type="entry name" value="TIGR02680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="301"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="348"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="953"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="248"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="451"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="753"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="315"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="362"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="1381" mass="153737" checksum="2C10096C5B5788A3" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMB2</accession>
    <name>A0A0S2DMB2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Cell division protein FtsA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">ftsA</name>
        <name evidence="9" type="ORF">BV903_07570</name>
        <name evidence="11" type="ORF">D9T17_08100</name>
        <name evidence="10" type="ORF">FE772_20230</name>
        <name evidence="8" type="ORF">GLE_4127</name>
    </gene>
    <organism evidence="8 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 12">C3</strain>
        </source>
    </reference>
    <reference evidence="9 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">OH11</strain>
        </source>
    </reference>
    <reference evidence="10 15" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Self-interacts. Interacts with FtsZ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="5">Localizes to the Z ring in an FtsZ-dependent manner. Targeted to the membrane through a conserved C-terminal amphipathic helix.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the FtsA/MreB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000015">
        <property type="protein sequence ID" value="OPD64515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000021">
        <property type="protein sequence ID" value="ROU07488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948807.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4127"/>
    <dbReference type="EnsemblBacteria" id="ALN59469">
        <property type="protein sequence ID" value="ALN59469"/>
        <property type="gene ID" value="GLE_4127"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64515">
        <property type="protein sequence ID" value="OPD64515"/>
        <property type="gene ID" value="BV903_07570"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4127"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4069"/>
    <dbReference type="OMA" id="DGIIRHT"/>
    <dbReference type="OrthoDB" id="1044637at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009898">
        <property type="term" value="C:cytoplasmic side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02033">
        <property type="entry name" value="FtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020823">
        <property type="entry name" value="Cell_div_FtsA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003494">
        <property type="entry name" value="SHS2_FtsA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02491">
        <property type="entry name" value="SHS2_FTSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003101">
        <property type="entry name" value="FtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00842">
        <property type="entry name" value="FtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01174">
        <property type="entry name" value="ftsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 5 6" id="KW-0132">Cell division</keyword>
    <keyword evidence="1 5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FtsA" evidence="7">
        <location>
            <begin position="10"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR003101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD64515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROU07488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="416" mass="44523" checksum="2B6CE8FAE6F27E0E" modified="2016-02-17" version="1">MNRKGDKSLIVGLDIGTSKVVALVGEYTPSDGRPGNPIEVIGIGSHESRGLKRGVVVDIESTVQSIQRAIEEAELMAGCEIRSVYASISGNHIQCRNSQGIAPIRDGEVTYGDLDRVLEAAKAVAIPADQKILHAIPRDYVLDDSQEGIRNPVGMTGVRLEVHAHLVVCAQSAAANISKCVQRCGLQVDDLILGVLASSNAVLTNDERELGVILVDIGAGTTDIAVFVQGAIAHSASLPIAGDKVTEDIAHMLRTPTPEAEQIKVRYACALAQMATAEESIQVPSVGDRPPRRMPRHSLAQAVQARYEEIFEMIQAELRRSGFEHHVRAGMVLTGGAAKMEGVVELAEEMLQMPVRVGIPQHVTGLGEVVGNPVHATGVGLLLMGSQIENPRRPVISTGRAGSFLSKLKNWYRGEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMQ4</accession>
    <name>A0A0S2DMQ4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Tail-specific protease</fullName>
            <ecNumber evidence="7">3.4.21.102</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">prc</name>
        <name evidence="8" type="ORF">FE772_21830</name>
        <name evidence="7" type="ORF">GLE_4472</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase S41A family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.102" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949080.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4472"/>
    <dbReference type="EnsemblBacteria" id="ALN59813">
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    <dbReference type="KEGG" id="lez:GLE_4472"/>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="Peptidase_S41_CPP"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
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        <property type="entry name" value="PDZ_sf"/>
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        <property type="entry name" value="Peptidase_S41A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
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    <dbReference type="InterPro" id="IPR020992">
        <property type="entry name" value="Tail_Prtase_C"/>
    </dbReference>
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        <property type="entry name" value="TSP_N"/>
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        <property type="entry name" value="DUF3340"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17804">
        <property type="entry name" value="TSP_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00225">
        <property type="entry name" value="prc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242345" evidence="5">
        <location>
            <begin position="25"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="6">
        <location>
            <begin position="248"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="637"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="637"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW27892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="737" mass="80554" checksum="BAE83101771F0377" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMX5</accession>
    <name>A0A0S2DMX5_LYSEN</name>
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        <recommendedName>
            <fullName evidence="5">Flagellar P-ring protein</fullName>
        </recommendedName>
        <alternativeName>
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        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">flgI</name>
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        <name evidence="6" type="ORF">GLE_4633</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 5">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the FlgI family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW28016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4633"/>
    <dbReference type="EnsemblBacteria" id="ALN59974">
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        <property type="gene ID" value="GLE_4633"/>
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    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009428">
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="FlgI"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Flag_FlgI"/>
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        <property type="entry name" value="PTHR30381"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FLGPRINGFLGI"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
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    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5034526516" description="Flagellar P-ring protein" evidence="5">
        <location>
            <begin position="31"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW28016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="385" mass="40157" checksum="B6A824CBD453E743" modified="2016-02-17" version="1" precursor="true">MNANFAVYKHTLVAFGLAVALAVAAPAARAAEDAAAGSVRLKDLGRFLGRRDNMLVGYGIVTGLAGSGDAPRNQATRQAMQNLLSQFDLTVPLDQIQSRNVAMVMITATLPATSNIGDKIDVNVTSTGDARSIAGGTLIMSALRGPDKRTYALAQGPVTVGGYRFDGNGNLRQKNHPTVGVVSEGATVEVPVRAQIAAQDGRVDYVLKNSDAVTSERIAARINQAFGAGAAVSLDPETVRIRAPQDPGRLNAFVASIEALAVVPDVASRVVINERTGTVAAGGDTRISPVTISHGDLRVSIDTEYTASQPNFIGVADDSVRSLIVGNSRLDVDESGQRVAQTYKQTTVAELVASLARARVGTRDVIAILQAIKAAGALHADLVVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN05</accession>
    <name>A0A0S2DN05_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Flagellar biosynthetic protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="10">Flagellar biosynthetic protein FliR</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Type III secretion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fliR</name>
        <name evidence="9" type="ORF">BV903_14215</name>
        <name evidence="10" type="ORF">FE772_22555</name>
        <name evidence="8" type="ORF">GLE_4625</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FliR/MopE/SpaR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000036">
        <property type="protein sequence ID" value="OPD63282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949192.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4625"/>
    <dbReference type="EnsemblBacteria" id="ALN59966">
        <property type="protein sequence ID" value="ALN59966"/>
        <property type="gene ID" value="GLE_4625"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63282">
        <property type="protein sequence ID" value="OPD63282"/>
        <property type="gene ID" value="BV903_14215"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4625"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4561"/>
    <dbReference type="OMA" id="AMAVMND"/>
    <dbReference type="OrthoDB" id="1942709at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002010">
        <property type="entry name" value="T3SS_IM_R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30065">
        <property type="entry name" value="PTHR30065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01311">
        <property type="entry name" value="Bac_export_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00953">
        <property type="entry name" value="TYPE3IMRPROT"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="69"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="162"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD63282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW28010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="250" mass="25715" checksum="5611A687A16113D0" modified="2016-02-17" version="1">MNAYVAAIALLTLRIGPVFVLSPPFSLVRVPQRVRVCLVLALAALLAPVLPMALPANEGAFVLSALSELLIGLTFAVALQMAFAALSFAGRVLDVQAGYGLALVIDPSTRAQSPLFGTIFSLAAAAIFFASNGHLELVRVLAASAHAMPIGLPVMAGTPQALIGYLGLLMSTAFGAIAAVTVTLFLIDLTIALLSRALPQMNALMLGLQVKTIATLVMLTLSAGLLAPVALRLIRHALDFMAALGPGGAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DND5</accession>
    <name>A0A0S2DND5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FE772_22430</name>
        <name evidence="9" type="ORF">GLE_4598</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949170.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4598"/>
    <dbReference type="EnsemblBacteria" id="ALN59939">
        <property type="protein sequence ID" value="ALN59939"/>
        <property type="gene ID" value="GLE_4598"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4598"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4533"/>
    <dbReference type="OMA" id="INQDHNV"/>
    <dbReference type="OrthoDB" id="357683at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071702">
        <property type="term" value="P:organic substance transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010917">
        <property type="entry name" value="TonB_rcpt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="SSF49452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01156">
        <property type="entry name" value="TONB_DEPENDENT_REC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726820" evidence="6">
        <location>
            <begin position="29"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="129"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="7">
        <location>
            <begin position="306"/>
            <end position="984"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN59939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="986" mass="109036" checksum="4B1FAECAE610C1E2" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNI9</accession>
    <name>A0A0S2DNI9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4767</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60108">
        <property type="protein sequence ID" value="ALN60108"/>
        <property type="gene ID" value="GLE_4767"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4767"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4700"/>
    <dbReference type="OMA" id="VRINRYE"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="14"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="86" mass="9300" checksum="10670D0D53AF1689" modified="2016-02-17" version="1">MTARFEDGTDAVRINRYEKRVHDADLATARRIAQSLGVPLAFLYADTVVLAEAILTLGLLSKSEQRKAVADLKARLAQAGGASEKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNT9</accession>
    <name>A0A0S2DNT9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipoyl synthase</fullName>
            <ecNumber evidence="6">2.8.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lip-syn</fullName>
            <shortName evidence="6">LS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoic acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Sulfur insertion protein LipA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">lipA</name>
        <name evidence="9" type="ORF">FE772_21845</name>
        <name evidence="8" type="ORF">GLE_4475</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[[Fe-S] cluster scaffold protein carrying a second [4Fe-4S](2+) cluster] + 4 H(+) + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + 2 5'-deoxyadenosine + [[Fe-S] cluster scaffold protein] + 4 Fe(3+) + 2 hydrogen sulfide + 2 L-methionine + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:16585"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:14568"/>
            <dbReference type="Rhea" id="RHEA-COMP:14569"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33722"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="2.8.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the radical SAM superfamily. Lipoyl synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.8" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949083.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4475"/>
    <dbReference type="EnsemblBacteria" id="ALN59816">
        <property type="protein sequence ID" value="ALN59816"/>
        <property type="gene ID" value="GLE_4475"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4475"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4412"/>
    <dbReference type="OMA" id="PYCDIDF"/>
    <dbReference type="OrthoDB" id="1184806at2"/>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00593"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016992">
        <property type="term" value="F:lipoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102552">
        <property type="term" value="F:lipoyl synthase activity (acting on glycine-cleavage complex H protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102553">
        <property type="term" value="F:lipoyl synthase activity (acting on pyruvate dehydrogenase E2 protein)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="lipA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
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            <begin position="100"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
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        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
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        </ligand>
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        <location>
            <position position="99"/>
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        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
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        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
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            <position position="118"/>
        </location>
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            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
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        </ligand>
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        <location>
            <position position="121"/>
        </location>
        <ligand>
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        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00001264"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
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        <source>
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            <dbReference type="PROSITE" id="PS51918"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN59816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW27895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="345" mass="37849" checksum="114971B8F2976C42" modified="2016-02-17" version="1">MSDTASKTIPLTVVGAADPVANPAVLQSTTMTPGAKQLGGDKINRSPVQFADAPVLRKPSWIRVRIPSGNSVAQLKAKLRENRLVTVCEEASCPNIHECFGHGTATFMILGEVCTRRCSFCDVAHGRPKPPDPQEPVNLANTVADMGLKYVVVTSVDRDDLRDGGAQHFVDCIAAIRAQSPRTKIEVLTPDFRGKGRMERALEILANNPPDVFNHNVETVPDLYSNVRPGADYQWSLTLLQKFKAQHPNVATKSGIMLGLGETMEQVRATLRDLRAHDVDMITIGQYLQPTPHHHPVLRYWTPEEFKELEVYGMSLGFTHVASGPLVRSSYHADRQAIDAGFAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP54</accession>
    <name>A0A0S2DP54_LYSEN</name>
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        <submittedName>
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        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_24360</name>
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        <name type="scientific">Lysobacter enzymogenes</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
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    </dbReference>
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    <feature type="domain" description="ABC transporter" evidence="4">
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW28314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="253" mass="26854" checksum="D5D7442BA0780B25" modified="2016-02-17" version="1">MNSTNDGADALRLDGVRKDFGERHALQALSLKIAPGEVYALLGPNGAGKTTTLNLILGFLDPDAGRIEVAGIDVARDRLGARAKIAYLPETVMLHPQLDAIENLTYFALLGGRRIDASQARELLRQAGLQEEAHARRAGGFSKGMRQKVGLAIALAKDAQLLLLDEPTSGLDASAANDLSHGVRAASRRGVAVLMATHDLYRVKDVAHRLGILRAGRLLTERRTSELSASQIEALYLQELDAADPAPAGAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP83</accession>
    <name>A0A0S2DP83_LYSEN</name>
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        <submittedName>
            <fullName evidence="4">Phospholipase D Active site motif</fullName>
        </submittedName>
    </protein>
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        <name evidence="4" type="ORF">GLE_5182</name>
    </gene>
    <organism evidence="4 5">
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    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN60523">
        <property type="protein sequence ID" value="ALN60523"/>
        <property type="gene ID" value="GLE_5182"/>
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    <dbReference type="KEGG" id="lez:GLE_5182"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5102"/>
    <dbReference type="OMA" id="LFNPFAN"/>
    <dbReference type="OrthoDB" id="1881748at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
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        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595556" evidence="2">
        <location>
            <begin position="21"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="3">
        <location>
            <begin position="186"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="3">
        <location>
            <begin position="526"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="681" mass="75229" checksum="4E00D81503B0CA1E" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPD0</accession>
    <name>A0A0S2DPD0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TetR/AcrR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_06645</name>
        <name evidence="3" type="ORF">FE772_23755</name>
        <name evidence="1" type="ORF">GLE_4892</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="ALN60233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000012">
        <property type="protein sequence ID" value="OPD64710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949397.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000012.1"/>
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    <dbReference type="STRING" id="69.GLE_4892"/>
    <dbReference type="EnsemblBacteria" id="ALN60233">
        <property type="protein sequence ID" value="ALN60233"/>
        <property type="gene ID" value="GLE_4892"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64710">
        <property type="protein sequence ID" value="OPD64710"/>
        <property type="gene ID" value="BV903_06645"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4892"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4823"/>
    <dbReference type="OMA" id="LHDVVFH"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD64710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="222" mass="24326" checksum="9A9723C6AAF26A72" modified="2016-02-17" version="1">MATLQPAVAGEADARAAAAASAFLALTPDPALDAAARLVAAYGVAALRLERIATAAGLDEAQLRARFGCERRLRAALEQRFADGFVARVRQAMDRCRDGDWGGRLRAWVQTAVSAYLEQVALHDALFHDAHTHSKGYDRQAWQDNPVIDQLVELLEGGIAARVWAAPDPRMTAVIFFSAMHGAVDRAIACGDAQTRPAETRHRLVQTLVGHFERNVQWWSRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPG3</accession>
    <name>A0A0S2DPG3_LYSEN</name>
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        <submittedName>
            <fullName evidence="9">Oxidoreductase, 2OG-Fe(II) oxygenase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLE_5137</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_5137"/>
    <dbReference type="EnsemblBacteria" id="ALN60478">
        <property type="protein sequence ID" value="ALN60478"/>
        <property type="gene ID" value="GLE_5137"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5137"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5062"/>
    <dbReference type="OMA" id="NVWHEGE"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
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        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0847">Vitamin C</keyword>
    <keyword evidence="7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="8">
        <location>
            <begin position="111"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="277"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="444"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN60478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="513" mass="55290" checksum="C3F46BA98F493D91" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPN2</accession>
    <name>A0A0S2DPN2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribonuclease P protein component</fullName>
            <ecNumber evidence="6">3.1.26.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rnpA</name>
        <name evidence="6" type="ORF">GLE_5342</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.26.5" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5342"/>
    <dbReference type="EnsemblBacteria" id="ALN60683">
        <property type="protein sequence ID" value="ALN60683"/>
        <property type="gene ID" value="GLE_5342"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5342"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5258"/>
    <dbReference type="OMA" id="LHWRTGD"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000100">
        <property type="entry name" value="RNase_P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33992">
        <property type="entry name" value="PTHR33992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00825">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00188">
        <property type="entry name" value="rnpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="92"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN60683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="117" mass="12274" checksum="CB8BD4D9803E7984" modified="2016-02-17" version="1">MALPVLALHFQADADVPARLGLAVSRKVDPNAVGRNRIKRVFRDAFRHLRAELAPGDYVLVARPGASKLSGEELRAAFHSLLKRAGARSALALPETAAPGTMPAASPSHPTPDPGPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPN5</accession>
    <name>A0A0S2DPN5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5064</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60405">
        <property type="protein sequence ID" value="ALN60405"/>
        <property type="gene ID" value="GLE_5064"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5064"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595599" evidence="1">
        <location>
            <begin position="23"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="94" mass="9373" checksum="EF97CB96985CBA37" modified="2016-02-17" version="1">MVAAFFATALPAAGFFSAGLFAADSFATPRRGPRFDAGVFAPAASAGAIAARADVRAVAFLAMAAPRIGAAANEKGRDANVPIGAAARYRSGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPZ2</accession>
    <name>A0A0S2DPZ2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">M48 family metallopeptidase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="10">Peptidase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Peptidase, M48 family</fullName>
            <ecNumber evidence="9">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BV903_04915</name>
        <name evidence="11" type="ORF">FE772_25770</name>
        <name evidence="9" type="ORF">GLE_5333</name>
    </gene>
    <organism evidence="9 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">C3</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000009">
        <property type="protein sequence ID" value="OPD65082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949728.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5333"/>
    <dbReference type="EnsemblBacteria" id="ALN60674">
        <property type="protein sequence ID" value="ALN60674"/>
        <property type="gene ID" value="GLE_5333"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65082">
        <property type="protein sequence ID" value="OPD65082"/>
        <property type="gene ID" value="BV903_04915"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5333"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5250"/>
    <dbReference type="OMA" id="QWEVNLI"/>
    <dbReference type="OrthoDB" id="1530824at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595554" evidence="7">
        <location>
            <begin position="19"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="8">
        <location>
            <begin position="61"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN60674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD65082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW28549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="267" mass="28434" checksum="3DE16773DB8120B4" modified="2016-02-17" version="1">MKRILLGLTIAAAVAACATTTSPTGRTQRVGAVSQAQLDQMGEQAFAETKKKERISTDARQNAYVRCVVSSITRELPPGWQANWEVAVFVDSSPNAFALPGGKVGVNTGIFTVAKNQDQLAAVISHEIGHVVSRHHDERITRQMGSQTALNILGSLLGARYGEGAASATSQLGGAALQTAFLLPGSRTQESEADVVGQRLMAQAGYDPRQAVNLWENMISASSSRPPQWLSTHPDPQARIHELNARAGALIPVYEQARAAGRTPRCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPZ9</accession>
    <name>A0A0S2DPZ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_11130</name>
        <name evidence="4" type="ORF">FE772_24795</name>
        <name evidence="2" type="ORF">GLE_5116</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000026">
        <property type="protein sequence ID" value="OPD63854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949566.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60457">
        <property type="protein sequence ID" value="ALN60457"/>
        <property type="gene ID" value="GLE_5116"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63854">
        <property type="protein sequence ID" value="OPD63854"/>
        <property type="gene ID" value="BV903_11130"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5116"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5041"/>
    <dbReference type="OrthoDB" id="2232739at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595956" evidence="1">
        <location>
            <begin position="26"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="156" mass="17203" checksum="86C668AF89FAB5AB" modified="2016-02-17" version="1">MNSARALRPALLACIAALCCACAHARSNPPPAPEALEDIVVAEPAAADDIDYVFKMSCRDSPGLKRRHVVVEGYVTSDNAREQRSGLSALVIDGVALDALALREINREFPPDAVQDRPWMRCDRGTIEFTVPYNNADKRGRVRFKIDSDRQIELVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQC4</accession>
    <name>A0A0S2DQC4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DUF350 domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Inner membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BV903_05340</name>
        <name evidence="10" type="ORF">FE772_00405</name>
        <name evidence="8" type="ORF">GLE_5434</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0719 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000010">
        <property type="protein sequence ID" value="OPD64919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949805.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5434"/>
    <dbReference type="EnsemblBacteria" id="ALN60775">
        <property type="protein sequence ID" value="ALN60775"/>
        <property type="gene ID" value="GLE_5434"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64919">
        <property type="protein sequence ID" value="OPD64919"/>
        <property type="gene ID" value="BV903_05340"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5434"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5350"/>
    <dbReference type="OMA" id="VLNAACM"/>
    <dbReference type="OrthoDB" id="1807657at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007140">
        <property type="entry name" value="DUF350"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03994">
        <property type="entry name" value="DUF350"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="13"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN60775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD64919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW24356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="135" mass="13502" checksum="796F419F8BC344B7" modified="2016-02-17" version="1">MDAPINAQSFLNFLAYAGTGIGVLILAALAVSLITPHRELSLIRSGNAAAATGFAGTLVGLALPLHSAISNSVSLVDAAIWGAAAVVVQVFAYLIARLVAPKLSQQITDGQVGAGVFYAGVSVSVGLINAAAMTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQJ8</accession>
    <name>A0A0S2DQJ8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_05435</name>
        <name evidence="4" type="ORF">FE772_00485</name>
        <name evidence="2" type="ORF">GLE_5453</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 6">B25</strain>
        </source>
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    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
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            <begin position="1"/>
            <end position="26"/>
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            <begin position="27"/>
            <end position="72"/>
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    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24367.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="72" mass="7794" checksum="E44B5D7B3344227A" modified="2016-02-17" version="1">MIRKTKLMALCAFAFGLSFAASSAIAACNVSCFNTCKTNAINRCIANGGTQEDCNMDTTYYQCYRNCGCIIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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    </evidence>
    <evidence type="ECO:0000313" key="3">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="102" mass="11812" checksum="CB3B70A5FCAED5CC" modified="2016-02-17" version="1">MSAQDSAYAPQWRDYRARRFWFFAVWLGGFLGLEVVTFGVLPLMPKAMADAIWVAVGVAWLLGWGAMAIRWQRFPCPRCDRPFLLLRPFSRECGYCGLARYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <dbReference type="EnsemblBacteria" id="ALN60878">
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    <dbReference type="PATRIC" id="fig|69.6.peg.5456"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="50" mass="5729" checksum="FA1CB99C1375A97D" modified="2016-02-17" version="1">MTGALIYWISLRAVANTSKHREDPESVRAKLLAVQERIEGRKKAQVLHEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQS4</accession>
    <name>A0A0S2DQS4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UPF0149 family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">YecA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_05160</name>
        <name evidence="3" type="ORF">FE772_00235</name>
        <name evidence="1" type="ORF">GLE_5392</name>
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    <organism evidence="1 4">
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        <lineage>
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    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60733.1"/>
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    </dbReference>
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        <property type="protein sequence ID" value="QCW24326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949773.1">
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_5392"/>
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        <property type="gene ID" value="GLE_5392"/>
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        <property type="gene ID" value="BV903_05160"/>
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    </dbReference>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="OPD64884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="235" mass="26332" checksum="961F98B55CC7BDA6" modified="2016-02-17" version="1">MKAPAYLDDDQIERLADLLDQRAVPYKGFNLEALDGYLSALAVGPGQPAPADWQPAVWGGKEPRWNDQAEADQVQALLIGHWNMVSARVRHGDDDLPDHLAPLLWLPEEPDTEQPDELDVGRDWALGFFRGVELHEATWETWLDENDWIDEIFVLFDRLASGEVLGEDPAAPPAQLSYRERLEIVAGLPGMLADLQHHRVEALTPREPLRRAETPDRNEPCPCGSGKKYKKCCGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
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        </recommendedName>
    </protein>
    <gene>
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        </lineage>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
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        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW24457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0012"/>
    <dbReference type="EnsemblBacteria" id="ALN55371">
        <property type="protein sequence ID" value="ALN55371"/>
        <property type="gene ID" value="GLE_0012"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0012"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.18"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
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            <end position="576"/>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN55371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW24457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="578" mass="62931" checksum="10CF8708861E02F7" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA58</accession>
    <name>A0A0S2DA58_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Short chain fatty acid transporter, putative</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Short-chain fatty acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_01225</name>
        <name evidence="2" type="ORF">GLE_0058</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN55417">
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        <property type="gene ID" value="GLE_0058"/>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
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        <location>
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        <location>
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            <end position="136"/>
        </location>
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        <location>
            <begin position="148"/>
            <end position="170"/>
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        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
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        <location>
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            <end position="278"/>
        </location>
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        <location>
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            <end position="306"/>
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        </location>
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        <location>
            <begin position="450"/>
            <end position="473"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="479" mass="50736" checksum="594C38C0EF7C3C3F" modified="2016-02-17" version="1">MTAAAPVADGPLARFALRSAAWAERWFPDAYVFAALGVVVVAVAALAFGATPTATAAAFGDGYWSLIPFTMQMAFVVIGGYVVATAPAVARLIDALARFPRSGRGAVCYVALVSMLTSLLSWGFSLVFGGLLVRALARREDLDMDYRAAGAAAYLGLGAVWAMGLSSSAAQLQANPASMPPGLLAITGVLPFSETIFLWQSIALTAALIAVSLLVCFVTAPRGASVKRANEFEGADRLAADERHAAALPPRTRPGEWLEYSPLITVLLAALSLGWLAYEFGQKPLVTAIASLNTYNFLFLTVGLVLHWRPRSFLNAVARAVPSTGGVLIQFPLYGGIASLLTAAKGADGQTLAHHLSSVFVHIASTDTFTLVMGVYSAVLGFFVPSGGGKWIIEAPYVMQAANDLQVHLGWAVQVYNAAEALPNLINPFWMLPLLGVLGLKARDIVGFTFIQLLVHIPLVLGLLWLLGLTLTYHPPVMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA80</accession>
    <name>A0A0S2DA80_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4272 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_01380</name>
        <name evidence="2" type="ORF">GLE_0091</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW24528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945790.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0091"/>
    <dbReference type="EnsemblBacteria" id="ALN55450">
        <property type="protein sequence ID" value="ALN55450"/>
        <property type="gene ID" value="GLE_0091"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0091"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.96"/>
    <dbReference type="OMA" id="YLLEWAL"/>
    <dbReference type="OrthoDB" id="1236284at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025368">
        <property type="entry name" value="DUF4272"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14094">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="341" mass="37331" checksum="028BF030BCE09F35" modified="2016-02-17" version="1">MPLLINAYSTLASPPPPAFLAQPPARRDRSDPELVPHLQGFVGYVMSTVEDGMDARTFGVLRHLQRVQTQFSFEVDERDFDALAAWGEAANVLCFLPDGSVRDAAGNVLASRGEPPVEADAALPYPSDARERKRRSEAELQQLGAAPPAHLPPVLGAGEVRLREADETMRRMLALCAVAVRAESLSSQPLSVEEIRAKLGPGVAALSPAERAFIAADKPDEETWANQGWRYESAALLQWALGLSDILPAPTAICDAGRVARVAINHADEAAIAGARLRPLPELLDALDAIYRRHWLVRQARLDDKPAPIGLHPSVVYERHYALNWLLRFDEQDWDEVGTPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAF9</accession>
    <name>A0A0S2DAF9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Hydrolase, alpha/beta fold family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_05855</name>
        <name evidence="2" type="ORF">GLE_0117</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000010">
        <property type="protein sequence ID" value="OPD65006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55476">
        <property type="protein sequence ID" value="ALN55476"/>
        <property type="gene ID" value="GLE_0117"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65006">
        <property type="protein sequence ID" value="OPD65006"/>
        <property type="gene ID" value="BV903_05855"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0117"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.120"/>
    <dbReference type="OMA" id="RGLMPVP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="29"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD65006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="288" mass="30816" checksum="E0E426B746B727D0" modified="2016-02-17" version="1">MAAMQEFVVDTVFGRLAGLRNGRSHAPKLLALHGWLDNAASYVPLAPWLDGYDLVAPDLPGHGASAHLPAAAEYTLVSGARAALAVADALGWERFHLLGHSLGGATASMLAAAVPQRVDKLLLIEALGSLSEPEERVGTRLREAFAGMAAVGAKQLRVFDDIAIAIKVRMMANDLSEPVARLLVERGIAPVRGDAGAAGFVWRSDPRLTLTSAQRMSEGQMRSLIRAIDSPTCMIWADPAQSYMPDALRRERAGLLRDGVLHTRAGTHHLHMEQPAVVGELFRGFLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAU5</accession>
    <name>A0A0S2DAU5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SURF1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BV903_23720</name>
        <name evidence="7" type="ORF">FE772_02285</name>
        <name evidence="5" type="ORF">GLE_0292</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SURF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000085">
        <property type="protein sequence ID" value="OPD61433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945932.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000085.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0292"/>
    <dbReference type="EnsemblBacteria" id="ALN55650">
        <property type="protein sequence ID" value="ALN55650"/>
        <property type="gene ID" value="GLE_0292"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61433">
        <property type="protein sequence ID" value="OPD61433"/>
        <property type="gene ID" value="BV903_23720"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0292"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.291"/>
    <dbReference type="OMA" id="NRGWLPW"/>
    <dbReference type="OrthoDB" id="1908280at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd06662">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002994">
        <property type="entry name" value="Surf1/Shy1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045214">
        <property type="entry name" value="Surf1/Surf4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427">
        <property type="entry name" value="PTHR23427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02104">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50895">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN55650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD61433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW24672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="243" mass="26385" checksum="53653F4FB73598ED" modified="2016-02-17" version="1">MSRRGNLLLGWTLALAAIALFANLGLWQARRAVEKQAMLDAAARVLGERVPQPLSVADDPHRARDYDWAAGLGRFDERGPLLLDNQQRGGRAGVRVYRIFVPRAGLPLLVDLGWLPLGGERKLPAVPRPDGELALRGLLSAPPSVGIALGPGLGREGEGWLLTRVDTRAIAAATGLSAPLAPRVLRLDPDLTLGYERDLELLSNTLPPDKHRGYSLQWFALAAAVLATALILTFRRPRRGTDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB17</accession>
    <name>A0A0S2DB17_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Malate synthase</fullName>
            <ecNumber evidence="2">2.3.3.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">aceB</name>
        <name evidence="8" type="ORF">GLE_0222</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + glyoxylate + H2O = (S)-malate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18181"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.9"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.3.3.9" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0222"/>
    <dbReference type="EnsemblBacteria" id="ALN55581">
        <property type="protein sequence ID" value="ALN55581"/>
        <property type="gene ID" value="GLE_0222"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0222"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.224"/>
    <dbReference type="OMA" id="CHKRGAP"/>
    <dbReference type="OrthoDB" id="322024at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004474">
        <property type="term" value="F:malate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00727">
        <property type="entry name" value="malate_synt_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1220.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044856">
        <property type="entry name" value="Malate_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011076">
        <property type="entry name" value="Malate_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006252">
        <property type="entry name" value="Malate_synthA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001465">
        <property type="entry name" value="Malate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046363">
        <property type="entry name" value="MS_N_TIM-barrel_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42902">
        <property type="entry name" value="PTHR42902"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01274">
        <property type="entry name" value="Malate_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001363">
        <property type="entry name" value="Malate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51645">
        <property type="entry name" value="SSF51645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01344">
        <property type="entry name" value="malate_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001363-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN55581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="544" mass="59935" checksum="FCF5971A5A7D3B23" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB39</accession>
    <name>A0A0S2DB39_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Para-aminobenzoate synthase</fullName>
            <ecNumber evidence="2">2.6.1.85</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pabA</name>
        <name evidence="2" type="ORF">GLE_0408</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.6.1.85" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0408"/>
    <dbReference type="EnsemblBacteria" id="ALN55766">
        <property type="protein sequence ID" value="ALN55766"/>
        <property type="gene ID" value="GLE_0408"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0408"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.405"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046820">
        <property type="term" value="F:4-amino-4-deoxychorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Chorismate_bind" evidence="1">
        <location>
            <begin position="93"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="172" mass="19691" checksum="4D7B448DD83508A5" modified="2016-02-17" version="1">MHGRLSTVEHDDSALFAHIPRSFELVRYLRRFLAYDHLERCWHAVATGPLSARADDGAWLERMAALLQATPEAPALTHGARAEPVEFQLELDREAYRGRIRQCFAQIGDGETQEVCLTNLLRVRIELDPVELYRHLRRPHRRAKVLAVGEDMVRLRMDLLDAVLTQFPAVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="134" mass="15358" checksum="4E661FC2ECFC75D3" modified="2016-02-17" version="1">MTIVLKIRSCYSPDVDDLPGWVPASVDEVYYPLEMEIGEADRSGAHVFGLMIATPQGLAKHHRGRALQAFRNNQARTPGMGRKALLVIAPYRWTAVRERIDQQVQDCQRESWEASLACLREAFFWEYEGVAYRR</sequence>
</entry>
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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            <dbReference type="EMBL" id="ALN55787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="56" mass="6046" checksum="D9E31272AFE2364D" modified="2016-02-17" version="1">MTLPFIRVGDRSDHRGFGVGDGRGLNADESALARREDVIVRTVRRIAAHARAATTG</sequence>
</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="ALN55798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="208" mass="23844" checksum="C6DAD76949DDA309" modified="2016-02-17" version="1">MTPQQQFDQLIQSRNDEYELRRLRFFSSPDAVAYLPQRFDDPDRVVGFIARTLHAWATHPIPEYTAFDRFVEGGLQATEAKASRTAVGWKPETELSGYIHREGNKRTTQEYALLRALMRPADPHLVGGVNLYFYSHPVSEPEVLIRINLESPVPGSFEGLQRLSLRQIDASRALQALDHEREWASRSKQTFPEELDAMRLSLSKTTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBB7</accession>
    <name>A0A0S2DBB7_LYSEN</name>
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            <fullName evidence="8">Aspzincin_M35 domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <lineage>
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        </lineage>
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    <reference evidence="9 11" key="1">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
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        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
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    </dbReference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN55814">
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    <dbReference type="OrthoDB" id="169425at2"/>
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    </dbReference>
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    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Lys_MEP"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
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        </location>
    </feature>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN55814.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW24799.1"/>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="705" mass="77001" checksum="B1F02F355E0691E2" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBC3</accession>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </location>
    </feature>
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    </feature>
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    </feature>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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        </source>
    </evidence>
    <sequence length="149" mass="17273" checksum="53ED3FC69CBD595F" modified="2016-02-17" version="1">MSAAARSRASGDDRPHPRSAQTRTRLDDEQWRAVAARLPPTLIRRAQRNAPRYRRFVEDVLQVAAGDLRWRELEPNAGSWRTVYMRFLRWCEDGVWDGVIDALQAEPELARALRRRVDEHRRASGRRRQTAAPKTDAAARAHRRGDRAR</sequence>
</entry>
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    <accession>A0A0S2DBJ3</accession>
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        <submittedName>
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        </submittedName>
    </protein>
    <gene>
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    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55841.1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_0483"/>
    <dbReference type="EnsemblBacteria" id="ALN55841">
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        <property type="gene ID" value="GLE_0483"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0483"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.479"/>
    <dbReference type="OMA" id="AEPPTNI"/>
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    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009289">
        <property type="term" value="C:pilus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1090">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036937">
        <property type="entry name" value="Adhesion_dom_fimbrial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008966">
        <property type="entry name" value="Adhesion_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039458">
        <property type="entry name" value="FimA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16970">
        <property type="entry name" value="FimA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49401">
        <property type="entry name" value="SSF49401"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242261" evidence="1">
        <location>
            <begin position="22"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="178" mass="18087" checksum="9A653654C333CCA2" modified="2016-02-17" version="1">MKRASAIAFALALAVPGACFAADGTVHFEGSVIAPTCVLTNGPSPADIRVKLPAVAVSALSAAGEVAGRTPFIIRVADCDASTTQIQTFFEPGPTINTSNNNLTLQGGAGTAGNVELQVLNADYSQVLLGNPLALQNSQQVAVDTGGAALRYYAQYFATGAATAGSANSSVTFTMIYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBL7</accession>
    <name>A0A0S2DBL7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0567</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55925">
        <property type="protein sequence ID" value="ALN55925"/>
        <property type="gene ID" value="GLE_0567"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0567"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.561"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="38" mass="4681" checksum="935956E64732C6C9" modified="2016-02-17" version="1">MRSLHHFWKRWFSIVSILNPIAQAYRFPIDRTHKETPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBR8</accession>
    <name>A0A0S2DBR8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD dependent oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">NAD(P)/FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_03815</name>
        <name evidence="2" type="ORF">GLE_0621</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946169.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0621"/>
    <dbReference type="EnsemblBacteria" id="ALN55979">
        <property type="protein sequence ID" value="ALN55979"/>
        <property type="gene ID" value="GLE_0621"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0621"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.613"/>
    <dbReference type="OMA" id="ALMLPDW"/>
    <dbReference type="OrthoDB" id="2049098at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="1">
        <location>
            <begin position="8"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="306" mass="31852" checksum="59940066193F268F" modified="2016-02-17" version="1">MTDDRLLDAIVIGGSFAGLSAALQLARARRSVRILDAGRPRNRFADAAHGFFSRDGEDPRTLVAAAQAQLRRYPSARVIAAEALRASAIEGGFEVVAGDGGVLAARKLVLAFGVNDVLPELPGAAERWGKSVLHCPYCHGYEFAGQRLGVLQSASFSAQKALLVADWGPTTLYLNGEPAPDAQLAAQLAQRGVAIEPAPIAELLGAEQSLSALRLADGREAAIDALFVASRTRLNSALAEQLGCAIEDGPLGPVIRTDDSRQTTVAGVYAAGDIARPMHNATWAASDGVTAGASAHQALVFQPLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBS5</accession>
    <name>A0A0S2DBS5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase sigma factor</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">RNA polymerase sigma-E factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_03805</name>
        <name evidence="3" type="ORF">GLE_0619</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949934.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0619"/>
    <dbReference type="EnsemblBacteria" id="ALN55977">
        <property type="protein sequence ID" value="ALN55977"/>
        <property type="gene ID" value="GLE_0619"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0619"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.611"/>
    <dbReference type="OMA" id="TPIEQPR"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r4_2" evidence="2">
        <location>
            <begin position="107"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="166" mass="18652" checksum="5D26A5652E19B6AA" modified="2016-02-17" version="1">MPSNAAVLTSLLVTERERLLRYLGRYLDRATAEDALQSMYFKVIAVAGEPPIADARNYLYRLAHHHAVDQGRSEARRRKLREAAAACLEEDETPDTARVALARDELERVARAACELPEPSKRIFMLNRFEGLTQREIAQLLGVSSTTVEKHIQRALRLLDQARGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBW4</accession>
    <name>A0A0S2DBW4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase-like hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0662</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0662"/>
    <dbReference type="EnsemblBacteria" id="ALN56020">
        <property type="protein sequence ID" value="ALN56020"/>
        <property type="gene ID" value="GLE_0662"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0662"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.651"/>
    <dbReference type="OMA" id="HTLDDSW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="228" mass="24307" checksum="6FD5185279119DC4" modified="2016-02-17" version="1">MALEFVPDAVLFDMDGLMLDSEQAMLETWREAAVAENLAAGDEVWLAMVGMHDRASLAHLSGHFGAEAAARLRDASYRLYDERVAAGLPRKRGLLELLDLLDAHRVPKAVATSTQRPRALAKLAASGLIDRFDAIVAGSDVEHPKPAPDIYLLAARELGVDVRRCVVLEDSEPGVRAALAAGATPIQVPDLVAPGEELRAFGHRIVASLEQAHGLLERALAQGAAEAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC06</accession>
    <name>A0A0S2DC06_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methylmalonate-semialdehyde dehydrogenase (Acylating)</fullName>
            <ecNumber evidence="4">1.2.1.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mmsA</name>
        <name evidence="4" type="ORF">GLE_0575</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.2.1.27" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0575"/>
    <dbReference type="EnsemblBacteria" id="ALN55933">
        <property type="protein sequence ID" value="ALN55933"/>
        <property type="gene ID" value="GLE_0575"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0575"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.568"/>
    <dbReference type="OMA" id="VGAAKEW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004491">
        <property type="term" value="F:methylmalonate-semialdehyde dehydrogenase (acylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07085">
        <property type="entry name" value="ALDH_F6_MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010061">
        <property type="entry name" value="MeMal-semiAld_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43866">
        <property type="entry name" value="PTHR43866"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01722">
        <property type="entry name" value="MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="3">
        <location>
            <begin position="23"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN55933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="507" mass="53260" checksum="D1FEBD92646BBBDB" modified="2016-02-17" version="1">MNDMHAVATDVATVKLLIDGEFVESSTAHWRDVVNPATQAVLARVPMATPAEIDAAVAAAQRAFKTWRKTPIGARARIFLKYQQLIREHMGELAAILTAEQGKTLPDAEGDVFRGLEVVEHAAAIGNLQLGELANNVAGGVDTYTLLQPLGVCAGITPFNFPAMIPLWMFPMAIATGNTFVLKPSEQDPLVTMRLCELALQAGIPKGVLNVVHGGETAVNAICDHPDIKAVSFVGSTKVGTHVYQRASLAGKRVQCMMGAKNHAVVLADANKEQTLNALAGAAFGAAGQRCMAASTAVLVGAANDWIADLVAKAKTLKVNAGTEAGTDVGPVISCAARERVEGLIASGVEQGATLELDGRAPAVPGYERGNFVGPTIFSGAAPGMRIYDEEIFGPVLVILRAETLDEAIELVNANPNGNGTAIFTQSGAAARRFQEDIDVGQVGINVPIPVPVPLFSFSGSRASKLGDLGPYGKQAVTFYTQTKTVTARWFDDDTLGHGVNTTISLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC18</accession>
    <name>A0A0S2DC18_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF2235 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_04195</name>
        <name evidence="3" type="ORF">GLE_0704</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946232.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0704"/>
    <dbReference type="EnsemblBacteria" id="ALN56062">
        <property type="protein sequence ID" value="ALN56062"/>
        <property type="gene ID" value="GLE_0704"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0704"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.692"/>
    <dbReference type="OMA" id="GSYPENE"/>
    <dbReference type="OrthoDB" id="348728at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018712">
        <property type="entry name" value="DUF2235"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09994">
        <property type="entry name" value="DUF2235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2235" evidence="2">
        <location>
            <begin position="3"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="483" mass="52714" checksum="FA13AE8253625447" modified="2016-02-17" version="1">MPKTILIFADGTGQAGGVRPDQQLSNIYKLFRATRVGPDSAIDPKRQVAFYDPGLGTATAAGRVRLNAWQRLKSLAGLACGLGFSRNVVDCYEAILKRYEPGDRIFLFGFSRGGYTVRCVANVLNLCGVPTGDGRGGPLPRAGRALRAIAEEAVTRVYEHGAGHPRERFESQREAIARRFRRKYAAGDDPHRGDVHPEFVGVFDAVAALGLPLPTRMLLILAGLLVALMAAIAIGAASESWLGGGGWIAFAATLAALGLSVAAAYLKATLRYASADVRGGGPRFHLALWNSEHYDRLLDPRIAQVRHALAIDENRRQFGRVTWGGSGNRQQIEEGRFKQRWFAGNHSDIGGSYPEDESRLSDIALAWMVDELQKLPQPIQLDRGKLQLYPDACGLQHCEIFAQRQRHPWLSRIAAWPRAARAPGPDLDPSVRERLQAQSVTICDLKTAYRPDALRRHRGLEAYYPAAAADVAAAAETSQPSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC23</accession>
    <name>A0A0S2DC23_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0708</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946236.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56066">
        <property type="protein sequence ID" value="ALN56066"/>
        <property type="gene ID" value="GLE_0708"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0708"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.696"/>
    <dbReference type="OMA" id="DIEVECF"/>
    <dbReference type="OrthoDB" id="393677at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="587"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="606" mass="64933" checksum="6C041E5962743C48" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC65</accession>
    <name>A0A0S2DC65_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946282.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56121">
        <property type="protein sequence ID" value="ALN56121"/>
        <property type="gene ID" value="GLE_0763"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0763"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.751"/>
    <dbReference type="OrthoDB" id="1812212at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594730" evidence="1">
        <location>
            <begin position="29"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="316" mass="32030" checksum="6897BD2CBD2419B4" modified="2016-02-17" version="1">MPAARLLALGVALSLAAACSRDPAPVPAATPAAAAPATPAAAPPATTPTAEAASAQVLGEVGGLRLEALSEVPAPPAEGEADVGGDCSVAAESAEARAAEAKGWKVFAQREWQGHRVVGVAVAPGVAAGMGCTSGGGRLLFFRDGRPLAQLLEPGAGASQIDSGVQGFDDGEDARRRGDAALGVFDWAVQRARVRFQNGVLALAALPEADLYCGGRAAVPRVEGVELKQARERLLARGWRAAPPEREEPGFVSGMVEAGYPEVEDCSGTGQGFCSFAYRNEAGDRLTLVTAGETPTARHAAVQCAGEGEPRGSDAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC80</accession>
    <name>A0A0S2DC80_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_19970</name>
        <name evidence="3" type="ORF">FE772_04600</name>
        <name evidence="1" type="ORF">GLE_0781</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000059">
        <property type="protein sequence ID" value="OPD62162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_MTAY01000059.1"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN56139">
        <property type="protein sequence ID" value="ALN56139"/>
        <property type="gene ID" value="GLE_0781"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD62162"/>
        <property type="gene ID" value="BV903_19970"/>
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    <dbReference type="KEGG" id="lez:GLE_0781"/>
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    <dbReference type="OMA" id="EQMLPDH"/>
    <dbReference type="OrthoDB" id="1917771at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD62162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="92" mass="10004" checksum="85278AF4060D7BA8" modified="2016-02-17" version="1">MRAEDVLPDQQNEVRLGDVLARKGSVAAFLANARVLADPAADAEARAQAERDTRELLPALRALGLFDVLEIRDAGVRDWVRAHLAALPPKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC98</accession>
    <name>A0A0S2DC98_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">GLE_0804</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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    </organism>
    <reference evidence="2 4" key="1">
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            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD64117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946309.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000021.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56162">
        <property type="protein sequence ID" value="ALN56162"/>
        <property type="gene ID" value="GLE_0804"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64117">
        <property type="protein sequence ID" value="OPD64117"/>
        <property type="gene ID" value="BV903_09510"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0804"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.793"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594957" evidence="1">
        <location>
            <begin position="24"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="110" mass="11021" checksum="F51E227A8CEE441D" modified="2016-02-17" version="1">MTLRTLVATAAVSAALFASAAHARTVRFDATSLVRGNTEAAALANAKQAAVNACTAQGGSVAGQPSAKIFRVLGTDQGGGDFIVTSYEATGSVACTKEVPDGDNNQTGNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCF6</accession>
    <name>A0A0S2DCF6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0682</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0682"/>
    <dbReference type="EnsemblBacteria" id="ALN56040">
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        <property type="gene ID" value="GLE_0682"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0682"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.670"/>
    <dbReference type="OMA" id="TRRNCAS"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="122" mass="12036" checksum="F06BDD9CFCB89838" modified="2016-02-17" version="1">MHDPLSAGRRLASRAIAWQAGATALVALAFLSLGASSALAAAVGGGAAVAGNLAAARMALGGGVQPAGSAIGRLLLGVIFKWVAVLTVLGLGMAVWRLPPLPMLVSLSAATLAFALANLLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCG4</accession>
    <name>A0A0S2DCG4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_04940</name>
        <name evidence="2" type="ORF">GLE_0855</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946347.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56213">
        <property type="protein sequence ID" value="ALN56213"/>
        <property type="gene ID" value="GLE_0855"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0855"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.844"/>
    <dbReference type="OrthoDB" id="1680909at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242651" evidence="1">
        <location>
            <begin position="20"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="292" mass="31356" checksum="E096BE5A2FFAD981" modified="2016-02-17" version="1">MKALPLLAALALCPTVALAGACENNFTSQGDPRNGAEYRTSTVVEGVGVGSALAQLRVIAQGNKYKYLNETGDARSGTLTMEYPRALGYEAFPVAFTATARDGGAELSVHTRTSRGTNFKDAESRAHLCGLLAQVKSGARGDALAASVRKAEGAGTSQVVQIAPRKLSDEIEKQIRNSLRGPGASPQIINERYKGRRYRIDGQLYTKETDTYGPRPNSHGRQVTFDIVKKGGLIRAAEVGVVAHTHTQIVCELARGQEGYADRLESGDYMTLTGTFRIYEGGQFILTGCRPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCR9</accession>
    <name>A0A0S2DCR9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0963</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946427.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0963"/>
    <dbReference type="EnsemblBacteria" id="ALN56321">
        <property type="protein sequence ID" value="ALN56321"/>
        <property type="gene ID" value="GLE_0963"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0963"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.950"/>
    <dbReference type="OMA" id="ARSANKM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
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        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="418"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="549" mass="58983" checksum="090A6FEFD387EF4D" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCY5</accession>
    <name>A0A0S2DCY5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo/keto reductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Oxidoreductase, aldo/keto reductase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_05460</name>
        <name evidence="2" type="ORF">GLE_0969</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </evidence>
    <sequence length="429" mass="46626" checksum="5A5E5D74EF1744CF" modified="2016-02-17" version="1">MSTAAATPPLRQWQLTLLAGGAALLAYASMYAFRKPFAAASFHGQHWLEVDYKVWLVVAQILGYMCSKFLGIGVIGGLRRERRAPLMLALIGTAWLALLGFALVPAPWNIACLFLNGLPLGMVWGLVFSYLEGRRTTEAMGAILASSFIMASGVVKSVGKWLLLSGVSEFWMPFLTGLLFLPPLLIALRLLERVPEPDAADRAARSQRLPMTRAERRAFVRRFLPGLALMIGCYVALTVVRDFRDNFEAELFADLGYGNNAGVFALIETPVALAVLALTAGLTWFRDNLRGLMALHALMFGGLLVAGIATLAFRAGALPPLWWLALVGFGLYLAYVPFNCVFYERLIATFRVAGNVGFLMYLSDAFGYLGSVAVLLAKEFSGLTLSWTQFFAHIVLALSVVGGACLLASAAYFHHRAGRHARTPALAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDK4</accession>
    <name>A0A0S2DDK4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipase (Triacylglycerol lipase)</fullName>
            <ecNumber evidence="3">3.1.1.3</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Triacylglycerol lipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_06310</name>
        <name evidence="3" type="ORF">GLE_1157</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.3" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1157"/>
    <dbReference type="EnsemblBacteria" id="ALN56515">
        <property type="protein sequence ID" value="ALN56515"/>
        <property type="gene ID" value="GLE_1157"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1157"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1142"/>
    <dbReference type="OMA" id="YYFSWSG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triglyceride lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242283" evidence="1">
        <location>
            <begin position="30"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="38"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="314" mass="32984" checksum="5C9FBD73F8869563" modified="2016-02-17" version="1">MSRLNLRRLFGAPVLFALLCCAAAFPASADDYTKTRYPVVLVHGLFGFDAIGGVYDYWFGIPQALRSGGAQVYVAQVAAANSNEVRGEQLIDQLETLQALHGYTKFNLVGHSQGGPTARYVAAVRPDLVASMTSIGSPHAGSKVADFIGTTVPDGSPLRPLIASFVNAFSSLIGALSGGQSSQDSLAALKALDSAGSARFNARYPQGMPTSACGSGAATAGGVRYYSFGGTSNSTHWFDASDPAMIAGGLLFAGEANDGLVGRCSSHWGQVIRDDYEWNHLDEVNQIAGLRGLFSANPTSVYRAHLNRLKNAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDL1</accession>
    <name>A0A0S2DDL1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1321</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56678">
        <property type="protein sequence ID" value="ALN56678"/>
        <property type="gene ID" value="GLE_1321"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1321"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1305"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="48" mass="5325" checksum="5838F228E0ABF914" modified="2016-02-17" version="1">MRQCVPARFTGGDDAFPEAGGNSRIGVWCGVRSRMQQRPGWARTKDQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE42</accession>
    <name>A0A0S2DE42_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1382</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1382"/>
    <dbReference type="EnsemblBacteria" id="ALN56739">
        <property type="protein sequence ID" value="ALN56739"/>
        <property type="gene ID" value="GLE_1382"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1382"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1364"/>
    <dbReference type="OMA" id="TEGYYFW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="399" mass="44303" checksum="5102E8D00E6BC8BC" modified="2016-02-17" version="1">MPAPLEGLATADPGTLPLSAASSLFQRLRASTPQLARRAPGEHDAARWREHRIGGRRYRVAQPVTFTPYAAARPCSARCLFCSENLRRHDGGAMAQTLRPGPDHFERLSAALAQLRGLPLSWSLSGLESSDDEDWFLRLLATLSAAERDGVQVEERVLYSNGAGFARGRGEELIAALRGFGLSWLELSRHHYDAARNQRIMRFRDGEPVADGAVFERVARQLSAALPLRQVCILQRGGIDDADGVRAYLDWARACGAGTVVFREFSRLDPGYRDNATRRYIDAERAPIDEVLAACMDAPWWPQLTPLRITEGYYFWNLRLREQDSGMEVVFESSDYAAMHRRHASGDIYKLVFHGNGRLCAGWQPDRDVLWPLHEDSAALREASDGASANGATAERADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE74</accession>
    <name>A0A0S2DE74_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-3-methyladenine glycosylase</fullName>
            <ecNumber evidence="2">3.2.2.-</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="3">DNA-3-methyladenine glycosylase 2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_08235</name>
        <name evidence="2" type="ORF">GLE_1582</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.2.-" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946895.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1582"/>
    <dbReference type="EnsemblBacteria" id="ALN56939">
        <property type="protein sequence ID" value="ALN56939"/>
        <property type="gene ID" value="GLE_1582"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1582"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1562"/>
    <dbReference type="OMA" id="RTVAAWY"/>
    <dbReference type="OrthoDB" id="1781735at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="1">
        <location>
            <begin position="60"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="229" mass="25294" checksum="DF4EEB5874B98B2E" modified="2016-02-17" version="1">MPRQVRGFDAQAAHAHLSRKCRRLGAWMKKVDRLENGPIPDDARWRQRFDPVDALARAILFQQLSGKAASTIVGRVEAAIGSARLHHDTLGRCDDATLRACGVSGNKLLALRDLSVREARGEIPDLRAMAHMDNDAIVAALVPIRGIGRWTVEMMLMFRLGRPDILPVDDLGIRKGAQFVDKLDAMPAPKALAQIGERWGPYRTYASLYLWRIADIGSGVAKPVDRSQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DER0</accession>
    <name>A0A0S2DER0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Periplasmic serine endoprotease DegP-like</fullName>
            <ecNumber evidence="4">3.4.21.107</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">degQ</name>
        <name evidence="7" type="ORF">GLE_1705</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>Acts on substrates that are at least partially unfolded. The cleavage site P1 residue is normally between a pair of hydrophobic residues, such as Val-|-Val.</text>
            <dbReference type="EC" id="3.4.21.107"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase S1C family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.107" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1705"/>
    <dbReference type="EnsemblBacteria" id="ALN57060">
        <property type="protein sequence ID" value="ALN57060"/>
        <property type="gene ID" value="GLE_1705"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1705"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1683"/>
    <dbReference type="OMA" id="NRSVSMR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011782">
        <property type="entry name" value="Pept_S1C_Do"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02037">
        <property type="entry name" value="degP_htrA_DO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010600084" description="Periplasmic serine endoprotease DegP-like" evidence="4">
        <location>
            <begin position="39"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="6">
        <location>
            <begin position="306"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="106"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="410"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR611782-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="523" mass="53668" checksum="FBEC5F4065F46000" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DER1</accession>
    <name>A0A0S2DER1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">Signal peptidase I</fullName>
            <ecNumber evidence="3 7">3.4.21.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">lepB</name>
        <name evidence="11" type="ORF">FE772_08830</name>
        <name evidence="10" type="ORF">GLE_1708</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.</text>
            <dbReference type="EC" id="3.4.21.89"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the peptidase S26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.89" evidence="3 7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946992.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1708"/>
    <dbReference type="EnsemblBacteria" id="ALN57063">
        <property type="protein sequence ID" value="ALN57063"/>
        <property type="gene ID" value="GLE_1708"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1708"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1686"/>
    <dbReference type="OMA" id="ACDAYIK"/>
    <dbReference type="OrthoDB" id="1741894at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019758">
        <property type="entry name" value="Pept_S26A_signal_pept_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019757">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Lys-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019756">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43390">
        <property type="entry name" value="PTHR43390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02227">
        <property type="entry name" value="sigpep_I_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00501">
        <property type="entry name" value="SPASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00760">
        <property type="entry name" value="SPASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00761">
        <property type="entry name" value="SPASE_I_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 7" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S26" evidence="9">
        <location>
            <begin position="47"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR600223-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN57063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW25754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="261" mass="29658" checksum="60D971A86AC935FF" modified="2016-02-17" version="1">MRWFEIVLVSLTLFTGVIWLLDKLVLAKRRAAREGLLDDGKEPVVVDYSKAFFPVLFVVLILRSFIAEPFRIPSNSMMPTLLTGDFILVNKFTYGLRLPISNQKVLPMGEPARGDVVVFRPPHHPEQDWIKRIIGLPGDKISYRDGRLTVNGEPVPYTPIGTYQGRGKGVEMTGAQELSEQIGNHVHRILLRTESPLLDQGEGDWVVPKGEYFVMGDNRDNSEDSRYWGFLPEQNLRGRAFLIWMNFDEGVDFSRIGNSIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DES5</accession>
    <name>A0A0S2DES5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">LysM peptidoglycan-binding domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Outer membrane antigenic lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_07865</name>
        <name evidence="3" type="ORF">GLE_1499</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946825.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1499"/>
    <dbReference type="EnsemblBacteria" id="ALN56856">
        <property type="protein sequence ID" value="ALN56856"/>
        <property type="gene ID" value="GLE_1499"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1499"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1480"/>
    <dbReference type="OMA" id="WTWPANG"/>
    <dbReference type="OrthoDB" id="1891666at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="53"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="256" mass="26641" checksum="0BC56A3A83E10894" modified="2016-02-17" version="1">MSETNRTPTLAMAACLLATLALIGCSSSVVREPSRGGRPAAPAQRPSVAKPGATVVVQRGEGLYRIAANNGIQMADLAAWNGLSPPYNLYPGQRLKLYPPGRGGSSSAGSSSAGSGGSRPSAPAPAPAAPIDSGIRWRWPADGPLLGRYVANEPTKQGIDIGGAPGTPVRAAADGVVVYSGTGLVGYGELIIVKHNEQWLSAYGHNRKRLVNEGQLVKSGQQIAEMGRSGAARDQLHFEVRYNAKPVDPLLYLPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFR2</accession>
    <name>A0A0S2DFR2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_09080</name>
        <name evidence="2" type="ORF">GLE_1764</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947035.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57119">
        <property type="protein sequence ID" value="ALN57119"/>
        <property type="gene ID" value="GLE_1764"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1764"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1740"/>
    <dbReference type="OrthoDB" id="1522673at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="292" mass="32141" checksum="051217A7373F2968" modified="2016-02-17" version="1">MIGIQENDPPPPQREDALFAIEGVLDLLWVEDQPDRLLSRIARQPVAGADADAQARDASAIAQAADGIERALYFAEDLQYFAGLIDGRPVCGQFAGADKLKPGHRVKAAVSRSGNALRAHAILDPQQGWLWIHHPRGSAADAKAERKLALRLFCCSYVGSALLCALAYWAQGLPLTALAQAQSWLLIGNAIVFGAMALSADYRMDRPSPSKNGPLRLLGFADPHRVDLSRYRIGDVEMRRHLGFIRANRQALRSGRMQAVETPELLRQSSERHRDVYDYRQAVADGKAALMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFR4</accession>
    <name>A0A0S2DFR4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_10330</name>
        <name evidence="2" type="ORF">GLE_2036</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947233.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000056.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57386">
        <property type="protein sequence ID" value="ALN57386"/>
        <property type="gene ID" value="GLE_2036"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2036"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2001"/>
    <dbReference type="OMA" id="SHAREMD"/>
    <dbReference type="OrthoDB" id="1330684at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="228" mass="26340" checksum="82CAEB1DC4B55FE1" modified="2016-02-17" version="1">MDKERGLSFELLDEWIAQYLKTEDSKSKPGPWERWTFALGLFVPGICAPVGVLLANETGLLLVRVGLIAEVVLLAVSLALLARREWATFARAHNTYAREMDGSYRLYRGIVEKLRKFSRRDIQRRLRFIEGMRGRVAYRMGLFTGGMERLGIVPVLVVLYLQFKDWRFGDWEALAKVNMVGALLLWALLISYLLSWWMVKLRNRVDLYESLLRDALAEDDGASRPERQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFZ0</accession>
    <name>A0A0S2DFZ0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA pseudouridine synthase B</fullName>
            <ecNumber evidence="5">5.4.99.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">tRNA pseudouridine(55) synthase</fullName>
            <shortName evidence="5">Psi55 synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">tRNA pseudouridylate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">tRNA-uridine isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">truB</name>
        <name evidence="10" type="ORF">FE772_10990</name>
        <name evidence="9" type="ORF">GLE_2178</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>uridine(55) in tRNA = pseudouridine(55) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:42532"/>
            <dbReference type="Rhea" id="RHEA-COMP:10101"/>
            <dbReference type="Rhea" id="RHEA-COMP:10102"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947341.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2178"/>
    <dbReference type="EnsemblBacteria" id="ALN57527">
        <property type="protein sequence ID" value="ALN57527"/>
        <property type="gene ID" value="GLE_2178"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2178"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2140"/>
    <dbReference type="OMA" id="ELQFIRW"/>
    <dbReference type="OrthoDB" id="1166299at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02573">
        <property type="entry name" value="PseudoU_synth_EcTruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01080">
        <property type="entry name" value="TruB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014780">
        <property type="entry name" value="tRNA_psdUridine_synth_TruB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015240">
        <property type="entry name" value="tRNA_sdUridine_synth_fam1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032819">
        <property type="entry name" value="TruB_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767">
        <property type="entry name" value="PTHR13767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09157">
        <property type="entry name" value="TruB-C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16198">
        <property type="entry name" value="TruB_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00431">
        <property type="entry name" value="TruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TruB_N" evidence="6">
        <location>
            <begin position="31"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="TruB_C_2" evidence="8">
        <location>
            <begin position="180"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="TruB-C_2" evidence="7">
        <location>
            <begin position="246"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN57527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW26118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="307" mass="32765" checksum="5344D7E4A3F45F1B" modified="2016-02-17" version="1">MRKRQWRNVDGLLLLDKPQGLSSNQALQQARHLFRAEKGGHTGSLDPLATGLLPLCFGEATKIAGLLLGARKAYTATAVLGLTTDSDDADGAPLRERPVPEFDPAEIEAALAPLRGTILQRAPIYSALKQGGEPLYAKARRGEAIEAPEREVSVHSLTLTGRDGPRLELHIECGSGTYVRSLVRDLGEALGCGAHVATLRRSWVEPFLAPAMVTLEQLRELAERGDERVLDALLLPIEAGLSGFEQVALDAVAAQRLGHGQAVACAEGEPGLVAIYGETGRCLGLGLRQAGGRLQPQRLFRWAAQGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG58</accession>
    <name>A0A0S2DG58_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1953</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57304">
        <property type="protein sequence ID" value="ALN57304"/>
        <property type="gene ID" value="GLE_1953"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1953"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="65" mass="6996" checksum="0AD182166D4355D0" modified="2016-02-17" version="1">MGSGFRRNDGRWVAYPIVGAXXXXXXXXXXXXXXXXXXXXXXXXXXXXSYRGRAAVASAFACASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG63</accession>
    <name>A0A0S2DG63_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">LexA repressor</fullName>
            <ecNumber evidence="12">3.4.21.88</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">lexA</name>
        <name evidence="17" type="ORF">BV903_20085</name>
        <name evidence="16" type="ORF">GLE_2207</name>
    </gene>
    <organism evidence="16 18">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="16 18" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">C3</strain>
        </source>
    </reference>
    <reference evidence="17 19" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">B25</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Hydrolysis of Ala-|-Gly bond in repressor LexA.</text>
            <dbReference type="EC" id="3.4.21.88"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 12 13">Belongs to the peptidase S24 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.88" evidence="12"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000060">
        <property type="protein sequence ID" value="OPD62131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947363.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000060.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2207"/>
    <dbReference type="EnsemblBacteria" id="ALN57556">
        <property type="protein sequence ID" value="ALN57556"/>
        <property type="gene ID" value="GLE_2207"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62131">
        <property type="protein sequence ID" value="OPD62131"/>
        <property type="gene ID" value="BV903_20085"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2207"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2169"/>
    <dbReference type="OMA" id="HVWLLPH"/>
    <dbReference type="OrthoDB" id="1933795at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06529">
        <property type="entry name" value="S24_LexA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00015">
        <property type="entry name" value="LexA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006200">
        <property type="entry name" value="LexA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039418">
        <property type="entry name" value="LexA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006199">
        <property type="entry name" value="LexA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006197">
        <property type="entry name" value="Peptidase_S24_LexA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015927">
        <property type="entry name" value="Peptidase_S24_S26A/B/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01726">
        <property type="entry name" value="LexA_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00717">
        <property type="entry name" value="Peptidase_S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00726">
        <property type="entry name" value="LEXASERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00498">
        <property type="entry name" value="lexA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12 13" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="4 12" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 12 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 12" id="KW-0678">Repressor</keyword>
    <keyword evidence="11 12" id="KW-0742">SOS response</keyword>
    <keyword evidence="9 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 12" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="LexA_DNA_bind" evidence="15">
        <location>
            <begin position="2"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S24" evidence="14">
        <location>
            <begin position="100"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="12">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="active site" description="For autocatalytic cleavage activity" evidence="12">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <feature type="active site" description="For autocatalytic cleavage activity" evidence="12">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="12">
        <location>
            <begin position="107"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ALN57556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="OPD62131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="221" mass="24044" checksum="45D9FDB81EFD6D26" modified="2016-02-17" version="1">MSLTDLRRALLAFLHERLAADGLPPSQQEICARFGFRQNRSAGYHLQALHEDGLIELLPGRARGIRLRPAGLREALAWRAEREGLDAPAARAGGNDEPLPILGRVAAGAPIGADAEAQAHVLVDRALFSPRPDYLLRVQGDSMREDGIFDGDLVAVHRTREARSGQVVVARLGEEITIKRLRIDADGIVLLPRNPDYAPIRVPADADFAIEGLYCGLVRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGM0</accession>
    <name>A0A0S2DGM0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_2201</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947359.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2201"/>
    <dbReference type="EnsemblBacteria" id="ALN57550">
        <property type="protein sequence ID" value="ALN57550"/>
        <property type="gene ID" value="GLE_2201"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2201"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2163"/>
    <dbReference type="OMA" id="LNRWHLM"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="94"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="299"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="402" mass="43375" checksum="FE4D7F830CE52285" modified="2016-02-17" version="1">MLQLLIYLRYLSVAGQMLTVVFVAQRLNLPIPARALLSISAGLLLFNVLSHWWWLAHREAGPRALALQLLVDLLALTALLYFSGGPANPFVSLYLVPVALAAIGLDIAPMLGLTVLTAALYTWLMGHHVELPHLHGSDFQLHVTGMWVNFLLSAGIMAVVLSRFMTIVREQRRSLSEARERAIRDESLSALGSLAAGTAHELNTPLATIGLLVDDWMSGDHPPAREDLELLRSQLAHCRDHVRALAEMARRGAAGESSVEPGDAFVHACVDRWRLLRPNATARFRGGAAGRRVRVDPGLQQALINLINNAADANAAAGVDEPVEVETGMREGRLNIAIRDRGAGPARIARPRRDHPGSGLGIGLLISKSSIERSRGTVKQSERDGGGCVTEVELPLVAEGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGP6</accession>
    <name>A0A0S2DGP6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GGACT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2412</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2412"/>
    <dbReference type="EnsemblBacteria" id="ALN57761">
        <property type="protein sequence ID" value="ALN57761"/>
        <property type="gene ID" value="GLE_2412"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2412"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2374"/>
    <dbReference type="OMA" id="FYARGWG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd06661">
        <property type="entry name" value="GGCT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009288">
        <property type="entry name" value="AIG2-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013024">
        <property type="entry name" value="GGCT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036568">
        <property type="entry name" value="GGCT-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06094">
        <property type="entry name" value="GGACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110857">
        <property type="entry name" value="SSF110857"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGACT" evidence="1">
        <location>
            <begin position="56"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="170" mass="18610" checksum="F6FA0AD654154AB5" modified="2016-02-17" version="1">MTSSEQNAELDADEREAMARLNRLRAIDIDAARTGDEAAGLEARFAGRWNADRRLAVYGTLAPGEPNHHHLSELPGHWRPGTVTGELVQIGWGADLGYPALRWSADAGEVAVQLFASEALPAHWARLDEFEGGQYLRILVPVRMADGTLEVANLYAAHPDAPRPEQPQPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGS0</accession>
    <name>A0A0S2DGS0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Amidohydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_2432</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57781">
        <property type="protein sequence ID" value="ALN57781"/>
        <property type="gene ID" value="GLE_2432"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2432"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2394"/>
    <dbReference type="OMA" id="ATVHPYD"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016812">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002195">
        <property type="entry name" value="Dihydroorotase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="PTHR21240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00482">
        <property type="entry name" value="DIHYDROOROTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595151" evidence="6">
        <location>
            <begin position="21"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro-rel" evidence="7">
        <location>
            <begin position="32"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN57781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="288" mass="31533" checksum="B3CD1571F835C642" modified="2016-02-17" version="1">MRRLFAILPLSLAVASFAVAAAPAPAPQPVFDVHVHLREGEASLKTYEREVADAKLKLAGFAGMWFGGPYQALQGDPDAIRRANDAHIALAAKHPEMLAVATVHPYDGQAALDELARIAGRGVKVLKLHPHTQQFDAADPRVLPLVRKAGELGVVVLFDNANILPGDSERLFNVAIQAPKTRFIFAHIGGMNFRFWNILALARTADDFFADNIFFDISATAVLMADSPVEKEFVWTLRNVGIGQVLLGSDYPQLPLAKAVDALDRLDLTDEEKEKIRIGNARRLFGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH25</accession>
    <name>A0A0S2DH25_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Ferripyoverdine receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">fpvA</name>
        <name evidence="13" type="ORF">GLE_2399</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2399"/>
    <dbReference type="EnsemblBacteria" id="ALN57748">
        <property type="protein sequence ID" value="ALN57748"/>
        <property type="gene ID" value="GLE_2399"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2399"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2361"/>
    <dbReference type="OMA" id="RATYSHK"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015344">
        <property type="term" value="F:siderophore uptake transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055072">
        <property type="term" value="P:iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010917">
        <property type="entry name" value="TonB_rcpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010105">
        <property type="entry name" value="TonB_sidphr_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01783">
        <property type="entry name" value="TonB-siderophor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01156">
        <property type="entry name" value="TONB_DEPENDENT_REC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0410">Iron transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0732">Signal</keyword>
    <keyword evidence="5 9" id="KW-0798">TonB box</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594788" evidence="10">
        <location>
            <begin position="42"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="12">
        <location>
            <begin position="95"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="11">
        <location>
            <begin position="305"/>
            <end position="734"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN57748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="735" mass="79880" checksum="D89AD9410B7C8817" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHE8</accession>
    <name>A0A0S2DHE8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphate-selective porin O and P</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947536.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2435"/>
    <dbReference type="EnsemblBacteria" id="ALN57784">
        <property type="protein sequence ID" value="ALN57784"/>
        <property type="gene ID" value="GLE_2435"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2435"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2397"/>
    <dbReference type="OMA" id="KPHENFF"/>
    <dbReference type="OrthoDB" id="1578713at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010870">
        <property type="entry name" value="Porin_O/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07396">
        <property type="entry name" value="Porin_O_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595569" evidence="1">
        <location>
            <begin position="25"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="487" mass="52082" checksum="E855B10D808F6952" modified="2016-02-17" version="1">MSHTDRAAYALALSLAACAAPAFAADSANAPASDADLRALVRQQAEQIRELSQRLSELERRQAAEPVATDPIQAQVAAAVADTRDDELAILQAQVAQQAATGGGSGDGARMNWRKGAPEFSSGDGRMTFRPRGRLLLDQTFTRGSSFGARNLSGSDLASARLGAEGEFGALGYKVEADFAGNEVTLKDAYLSYDTRLGGHAVEFYLGNKLKDRSLDGATSGVATPFMERNAVASVGGMQSGYFGLGLSAKVFGDGWHASLAVTGDDVGNAGDASDTVAYLARAHWNPLRGGDGFVHLGGWYWYEQLGADVASINKTSPVALGWNDQVRVSASSIANVDNDRAWGAELGAVYRSGWLFGERTVRTIESDTVGEVRHKASSVYAGWLLTGEKPGFSRRSGVWTATRVLRPVDQGGIGAFELAVRYDRYDFTDTARGGDGDAWTLGVNWYLNDWSRLMLNYVFWKTDNKVGAFQGPDSGRTLGLRAQVAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHE9</accession>
    <name>A0A0S2DHE9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Inner membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_12765</name>
        <name evidence="3" type="ORF">GLE_2543</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947622.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57892">
        <property type="protein sequence ID" value="ALN57892"/>
        <property type="gene ID" value="GLE_2543"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2543"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2504"/>
    <dbReference type="OMA" id="CIACCSM"/>
    <dbReference type="OrthoDB" id="2047758at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007401">
        <property type="entry name" value="DUF454"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35813">
        <property type="entry name" value="PTHR35813"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04304">
        <property type="entry name" value="DUF454"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016789">
        <property type="entry name" value="DUF454"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR016789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="128" mass="13971" checksum="EC12ABC0B21C3E60" modified="2016-02-17" version="1">MRWLWFALGWAMVALGVIGALLPVMPTTIFLILAVACFARSSPKFERRLLEHPRYGPALRLWREQGAISRKGKLFAGLGMAVGFVLFWWGAHPSRALALGVGLGFAASAAYVLSRPTPRPAPPDAPRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHG1</accession>
    <name>A0A0S2DHG1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Morphogene BolA protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2786</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the BolA/IbaG family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2786"/>
    <dbReference type="EnsemblBacteria" id="ALN58134">
        <property type="protein sequence ID" value="ALN58134"/>
        <property type="gene ID" value="GLE_2786"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2786"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2742"/>
    <dbReference type="OMA" id="TRVEIHR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002634">
        <property type="entry name" value="BolA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036065">
        <property type="entry name" value="BolA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01722">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003113">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82657">
        <property type="entry name" value="SSF82657"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="93" mass="9718" checksum="AE47068D00E0BB57" modified="2016-02-17" version="1">MSLPREQRVAAIRAAIEASLAPTALEIEDESHRHAGHAGAQDGRGHFRVAVVSAAFAGLNPIARHRAVYAAVGELMTTDIHALSISAKTPGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHT7</accession>
    <name>A0A0S2DHT7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Muramidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2601</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2601"/>
    <dbReference type="EnsemblBacteria" id="ALN57949">
        <property type="protein sequence ID" value="ALN57949"/>
        <property type="gene ID" value="GLE_2601"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2601"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2561"/>
    <dbReference type="OMA" id="FQIMGYH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024408">
        <property type="entry name" value="Muramidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11860">
        <property type="entry name" value="Muramidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Muramidase" evidence="1">
        <location>
            <begin position="26"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="198" mass="21723" checksum="D990A70A38119C74" modified="2016-02-17" version="1">METVMNRIVSPQAWKDLADRLGVDEACLKAVAEVESSGGGFMRPPSQLPKVLFEGHVFHRQTQGRFDASHPELSYPHWDRSKYSGSVAGEWKRLDAACALDRGAAFASASWGAFQIMGFNFAMCGFDDIEAFVAAHKQSAEAQLAAFSSFIRRPGLLDALRNKDWKGFAAAYNGLGFAKNSYDTKLATAYLRFGGRSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIM1</accession>
    <name>A0A0S2DIM1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Polyisoprenoid-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">YceI like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_13735</name>
        <name evidence="3" type="ORF">GLE_2747</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2747"/>
    <dbReference type="EnsemblBacteria" id="ALN58095">
        <property type="protein sequence ID" value="ALN58095"/>
        <property type="gene ID" value="GLE_2747"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2747"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2705"/>
    <dbReference type="OMA" id="GNYRAGF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007372">
        <property type="entry name" value="Lipid/polyisoprenoid-bd_YceI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036761">
        <property type="entry name" value="TTHA0802/YceI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04264">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00867">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101874">
        <property type="entry name" value="SSF101874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726665" evidence="1">
        <location>
            <begin position="24"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="YceI" evidence="2">
        <location>
            <begin position="28"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="201" mass="21423" checksum="06EE2824858B6C83" modified="2016-02-17" version="1">MNTSALCLLTSLALFAAAAGAAAAEPATYRIDPSHTYPSFEADHMGGLSKWRGKFNQSVGRIVLDKQAGTGSVEVAIAVASVDFGMDAMNEEAKKATLFDVAQFPTATYKGKLAGFKHGKPDKVVGELTLHGVTRPLDLDIAQFKCMPHPMYKREVCGADAGASFQRDRFGISAGKDYGFDMTVNLRIQVEAIVEESAAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIN6</accession>
    <name>A0A0S2DIN6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Methionine--tRNA ligase</fullName>
            <ecNumber evidence="16">6.1.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Methionyl-tRNA synthetase</fullName>
            <shortName evidence="16">MetRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16 21" type="primary">metG</name>
        <name evidence="22" type="ORF">FE772_15715</name>
        <name evidence="21" type="ORF">GLE_3161</name>
    </gene>
    <organism evidence="21 23">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="21 23" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 23">C3</strain>
        </source>
    </reference>
    <reference evidence="22 24" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 24">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 16">Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met)</text>
            <dbReference type="Rhea" id="RHEA:13481"/>
            <dbReference type="Rhea" id="RHEA-COMP:9667"/>
            <dbReference type="Rhea" id="RHEA-COMP:9698"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="16">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 16">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 16">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="16"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948088.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3161"/>
    <dbReference type="EnsemblBacteria" id="ALN58507">
        <property type="protein sequence ID" value="ALN58507"/>
        <property type="gene ID" value="GLE_3161"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3161"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3117"/>
    <dbReference type="OMA" id="SDMHGTP"/>
    <dbReference type="OrthoDB" id="761140at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006431">
        <property type="term" value="P:methionyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07957">
        <property type="entry name" value="Anticodon_Ia_Met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00814">
        <property type="entry name" value="MetRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02800">
        <property type="entry name" value="tRNA_bind_EcMetRS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00098">
        <property type="entry name" value="Met_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041872">
        <property type="entry name" value="Anticodon_Met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004495">
        <property type="entry name" value="Met-tRNA-synth_bsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023458">
        <property type="entry name" value="Met-tRNA_ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014758">
        <property type="entry name" value="Met-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029038">
        <property type="entry name" value="MetRS_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45765">
        <property type="entry name" value="PTHR45765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19303">
        <property type="entry name" value="Anticodon_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57770">
        <property type="entry name" value="SSF57770"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00398">
        <property type="entry name" value="metG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00399">
        <property type="entry name" value="metG_C_term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15 16 18" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="12 16 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 16" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 16 18" id="KW-0436">Ligase</keyword>
    <keyword evidence="9 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 16 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14 16 18" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 16 17" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 16 17" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="11 16" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="TRNA-binding" evidence="20">
        <location>
            <begin position="589"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="550"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="16">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="ALN58507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="QCW26875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="692" mass="75706" checksum="D3DDC88AF41882BA" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIP1</accession>
    <name>A0A0S2DIP1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58111">
        <property type="protein sequence ID" value="ALN58111"/>
        <property type="gene ID" value="GLE_2763"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2763"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2720"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="194" mass="20870" checksum="BD9C9DB900780D93" modified="2016-02-17" version="1">MIDCYRCQVTDNNQPGHGLFVARIGALNARTTLAESVTWPIVAMHNAAFSLGRASLQRSKNCAAAKRAVGAARAATAPVRLRRNLQRRGNGQVCVRRDQPLRGRGSRRSYRASPRLLWERREPRPRQCVYGGTFSADAIGRPGFDATGRSVVAACAAPTGQARGFCGSGASRDRANAFTAEPSVPTQRPGPRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJF5</accession>
    <name>A0A0S2DJF5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3428</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58773">
        <property type="protein sequence ID" value="ALN58773"/>
        <property type="gene ID" value="GLE_3428"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3428"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3378"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="69" mass="7741" checksum="AE04AB9A442EDA0D" modified="2016-02-17" version="1">MRIGLSHRRTVVVVQWRRWRERIKAIPLRPCEKANAALCASPGRALSSSVFACDAFFCASQRAHNASND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJG1</accession>
    <name>A0A0S2DJG1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Phosphate-binding protein PstS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pstS</name>
        <name evidence="10" type="ORF">FE772_16390</name>
        <name evidence="9" type="ORF">GLE_3314</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Part of the ABC transporter complex PstSACB involved in phosphate import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 6">The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the PstS family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948200.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3314"/>
    <dbReference type="EnsemblBacteria" id="ALN58660">
        <property type="protein sequence ID" value="ALN58660"/>
        <property type="gene ID" value="GLE_3314"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3314"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3264"/>
    <dbReference type="OMA" id="NAMDLWV"/>
    <dbReference type="OrthoDB" id="1222928at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042301">
        <property type="term" value="F:phosphate ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005673">
        <property type="entry name" value="ABC_phos-bd_PstS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002756">
        <property type="entry name" value="PstS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00975">
        <property type="entry name" value="3a0107s03"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242163" description="Phosphate-binding protein PstS" evidence="7">
        <location>
            <begin position="22"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="8">
        <location>
            <begin position="43"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN58660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW26980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="363" mass="37664" checksum="6AA1B5F87CC8B8FA" modified="2016-02-17" version="1">MKSSPARLAVLSLAIALTVAACGGGNQPNPAASGDAKTDAAAPAGDKVAAQITGAGATFIFPLLSKWSDDYNKATGAKVNYQSIGSGGGIAQIKAGTVDFGSSDKPLPSDELAAAGLGQFPSAIGGVVPVVNVDGIDAGKLRLTGPLLADVFMGKVAKWNDPAIAAANPGTTLPDLKINIVHRSDGSGTTFNFSNYLSKVSPEWKAKVGEGTSVQWPGGVGGKGNEGVASYVKQIKGSIGYVELAYAMQNKMAHTQLQNAAGQFVQPSAESFQAAASTADWASAKDFNLVITNAGGEKSWPITATNFILMYKTPKDAKRSADTRAFFKWAFENGQSQAQALDYVPLPPELVKQIEAYWGAEFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJQ1</accession>
    <name>A0A0S2DJQ1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Clumping factor B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58756">
        <property type="protein sequence ID" value="ALN58756"/>
        <property type="gene ID" value="GLE_3410"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3410"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3360"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="58" mass="6340" checksum="A2171292BD3C6CA1" modified="2016-02-17" version="1">MSDKNTVPGSSDPRPGHSPGYPEPQPKDREDAHRPKRPKPDPDEGGLDREPETGPDPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJU5</accession>
    <name>A0A0S2DJU5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Probable queuosine precursor transporter</fullName>
            <shortName evidence="1">Q precursor transporter</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_17010</name>
        <name evidence="2" type="ORF">GLE_3453</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3453"/>
    <dbReference type="EnsemblBacteria" id="ALN58798">
        <property type="protein sequence ID" value="ALN58798"/>
        <property type="gene ID" value="GLE_3453"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3453"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3401"/>
    <dbReference type="OMA" id="IFQKFFY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990397">
        <property type="term" value="P:queuosine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02088">
        <property type="entry name" value="Q_prec_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003744">
        <property type="entry name" value="YhhQ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34300">
        <property type="entry name" value="PTHR34300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02592">
        <property type="entry name" value="Vut_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00697">
        <property type="entry name" value="TIGR00697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="270" mass="29560" checksum="0A2841587B8D8EBC" modified="2016-02-17" version="1">MSAGENTIAFAAGQGTRTLQDRSLRLFIVLSSFFCVNAALAEFIGVKIFALEDTLGIAPLQWNLFGQTGSLNFTAGTLLWPVVFLMTDVINEFFGRRGVRLISWLAAMLIAYGFLFAFAAIALAPAGWWVKAAQAQGVPDYQAAFAAIFGQGMWSIGGSLVAFMLGQLIDVAVFHRIRSATGDKHIWLRATGSTAVSQLVDSFVVLYIAFVLGPQHWPIPQFLAISTVNYGYKMLAAFAMIPLIYLLRVWIHGYLGHERAKQLRDEAAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJZ0</accession>
    <name>A0A0S2DJZ0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Sec translocon accessory complex subunit YajC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10 11" type="primary">yajC</name>
        <name evidence="12" type="ORF">BV903_21585</name>
        <name evidence="14" type="ORF">D9T17_10580</name>
        <name evidence="13" type="ORF">FE772_17300</name>
        <name evidence="11" type="ORF">GLE_3514</name>
    </gene>
    <organism evidence="11 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 15">C3</strain>
        </source>
    </reference>
    <reference evidence="12 16" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 16">B25</strain>
        </source>
    </reference>
    <reference evidence="14 17" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">OH11</strain>
        </source>
    </reference>
    <reference evidence="13 18" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 18">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the YajC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000071">
        <property type="protein sequence ID" value="OPD61870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000024">
        <property type="protein sequence ID" value="ROU06961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948347.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3514"/>
    <dbReference type="EnsemblBacteria" id="ALN58858">
        <property type="protein sequence ID" value="ALN58858"/>
        <property type="gene ID" value="GLE_3514"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61870">
        <property type="protein sequence ID" value="OPD61870"/>
        <property type="gene ID" value="BV903_21585"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3514"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3458"/>
    <dbReference type="OMA" id="GMEMIIM"/>
    <dbReference type="OrthoDB" id="2082059at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003849">
        <property type="entry name" value="Preprotein_translocase_YajC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33909">
        <property type="entry name" value="PTHR33909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02699">
        <property type="entry name" value="YajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01853">
        <property type="entry name" value="YAJCTRNLCASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01323">
        <property type="entry name" value="YajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00739">
        <property type="entry name" value="yajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0811">Translocation</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN58858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OPD61870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW27131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROU06961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="116" mass="12124" checksum="67EB830B265F9009" modified="2016-02-17" version="1">MNLLDLLIAPAYAQAAAGAPSAGPLGSFGGLVLPLVLIAVMYFLIFRPQMKRAKEHRAMLEKLSKGDEVLTNGGIAGTVTNIGENFITVEIAPNVAIRVQRGAIANVLPKGTLKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK00</accession>
    <name>A0A0S2DK00_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ferredoxin</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">YfhL family 4Fe-4S dicluster ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BV903_08830</name>
        <name evidence="7" type="ORF">FE772_17365</name>
        <name evidence="5" type="ORF">GLE_3530</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000019">
        <property type="protein sequence ID" value="OPD64280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948359.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3530"/>
    <dbReference type="EnsemblBacteria" id="ALN58874">
        <property type="protein sequence ID" value="ALN58874"/>
        <property type="gene ID" value="GLE_3530"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64280">
        <property type="protein sequence ID" value="OPD64280"/>
        <property type="gene ID" value="BV903_08830"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3530"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3474"/>
    <dbReference type="OMA" id="DCCVPDD"/>
    <dbReference type="OrthoDB" id="1873445at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="31"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD64280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW27143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="82" mass="9216" checksum="F1EE944038B34709" modified="2016-02-17" version="1">MSLKINELCVNCDVCEPACPNQAIAQGESIYVIDPARCTECVGHYDEPQCVMVCPVECIDPDPEFVESQTQLLDKLRRLQQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK19</accession>
    <name>A0A0S2DK19_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Adenine DNA glycosylase</fullName>
            <ecNumber evidence="4 13">3.2.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">mutY</name>
        <name evidence="17" type="ORF">FE772_17400</name>
        <name evidence="16" type="ORF">GLE_3536</name>
    </gene>
    <organism evidence="16 18">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="16 18" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">C3</strain>
        </source>
    </reference>
    <reference evidence="17 19" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>Hydrolyzes free adenine bases from 7,8-dihydro-8-oxoguanine:adenine mismatched double-stranded DNA, leaving an apurinic site.</text>
            <dbReference type="EC" id="3.2.2.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="13">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the Nth/MutY family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.31" evidence="4 13"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3536"/>
    <dbReference type="EnsemblBacteria" id="ALN58880">
        <property type="protein sequence ID" value="ALN58880"/>
        <property type="gene ID" value="GLE_3536"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3536"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3480"/>
    <dbReference type="OMA" id="RDPYRVW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000701">
        <property type="term" value="F:purine-specific mismatch base pair DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03431">
        <property type="entry name" value="DNA_Glycosylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005760">
        <property type="entry name" value="A/G_AdeGlyc_MutY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004036">
        <property type="entry name" value="Endonuclease-III-like_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044298">
        <property type="entry name" value="MIG/MutY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029119">
        <property type="entry name" value="MutY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42944">
        <property type="entry name" value="PTHR42944"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00633">
        <property type="entry name" value="HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14815">
        <property type="entry name" value="NUDIX_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01084">
        <property type="entry name" value="mutY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01155">
        <property type="entry name" value="ENDONUCLEASE_III_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="12 13 16" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 13" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="15">
        <location>
            <begin position="67"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ALN58880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="QCW27148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="376" mass="41462" checksum="1EF4AE098591D555" modified="2016-02-17" version="1">MTARSQSANAPARSRRKPATAAAAAPAAAGDDTFAARLLAWFDVSGRHDLPWQHPRSPYRVWLSEIMLQQTQVKTAAPYFERFVARLPDLPALAAAEQDTVLGLWSGLGYYARARNLHAAAKLCVERHGGELPRDLDALTALPGIGRSTAAAILSQAWGDRHAILDGNVKRVLARYHGIDGFPGLPAVEKRLWALAESHLPPARMTDYTQAQMDLGATVCTRADPACILCPLQNDCVARVHGRTAELPVPKPGKAVPQRHAQVLWLLDRSGRVLLQRRPPTGIWAALWTLPQHEDDEQAERWFETHLDGEYADGEALAPIAHAFSHYKLELQPRRWRAVALRARVGDNDGLRWFAREELAELGIPAPIRKLIEAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKD7</accession>
    <name>A0A0S2DKD7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3366</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948242.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58712">
        <property type="protein sequence ID" value="ALN58712"/>
        <property type="gene ID" value="GLE_3366"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3366"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3316"/>
    <dbReference type="OrthoDB" id="2064325at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594892" evidence="1">
        <location>
            <begin position="27"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="139" mass="14100" checksum="F8AE491204CD21D6" modified="2016-02-17" version="1">MTPGKAALLTIALALPAALVQAQALAAPPRAVPVEVGGSEEWDACGSTGRVRGLKADGDGFLAVRAGPGADYAMLDKLGNGRLVYLCGSRGRWTAVVYAPAGADASACGVSWAIAEAEVYRGPCKSGWVNTAWIEVVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKE5</accession>
    <name>A0A0S2DKE5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type IV pilus assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pilX</name>
        <name evidence="3" type="ORF">GLE_3577</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3577"/>
    <dbReference type="EnsemblBacteria" id="ALN58921">
        <property type="protein sequence ID" value="ALN58921"/>
        <property type="gene ID" value="GLE_3577"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3577"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3521"/>
    <dbReference type="OMA" id="EANQEMC"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025746">
        <property type="entry name" value="PilX_N_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14341">
        <property type="entry name" value="PilX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="PilX_N" evidence="2">
        <location>
            <begin position="17"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="165" mass="18009" checksum="66E2CEA723E733AC" modified="2016-02-17" version="1">MNNRLRHGSLRSPRRQRGAVLYIALIMLILLALLGLVGMKVSGLQERMSTNYSNVNAAFQAAEQVARAKESDIQKTLFAGSGVYEANQEMCSPTFDPMTWSDPAENTNSKDVFTRRIDKCFAGSSIKVGNNKSEETSNIYQVSALGGDRDANASSIAVIDTVFIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKK5</accession>
    <name>A0A0S2DKK5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">AsnC family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Lrp/AsnC family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AsnC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BV903_18005</name>
        <name evidence="7" type="ORF">FE772_16930</name>
        <name evidence="5" type="ORF">GLE_3431</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000048">
        <property type="protein sequence ID" value="OPD62556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948288.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000048.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3431"/>
    <dbReference type="EnsemblBacteria" id="ALN58776">
        <property type="protein sequence ID" value="ALN58776"/>
        <property type="gene ID" value="GLE_3431"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62556">
        <property type="protein sequence ID" value="OPD62556"/>
        <property type="gene ID" value="BV903_18005"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3431"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3381"/>
    <dbReference type="OMA" id="NYKPFHD"/>
    <dbReference type="OrthoDB" id="1534467at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019885">
        <property type="entry name" value="Tscrpt_reg_HTH_AsnC-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00519">
        <property type="entry name" value="HTH_ASNC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD62556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW27068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="152" mass="17389" checksum="7FA99B89389A054F" modified="2016-02-17" version="1">MRLDETDRRILRVLQREGRIANAELAERVGLSPSPCLRRVRLLEEAGVIERYVAVLAPARLGLSMTLFTRVWLMTQDAETIDRFVAAMLRLDQVMECYIVLGECDAMLRVVVADLDDYRRFQTTHLTRANGIANVKTDLPSQVVKRSYELPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKQ1</accession>
    <name>A0A0S2DKQ1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rpsH</name>
        <name evidence="7" type="ORF">GLE_3776</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3776"/>
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        <property type="gene ID" value="GLE_3776"/>
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    <dbReference type="KEGG" id="lez:GLE_3776"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3720"/>
    <dbReference type="OMA" id="FDQGYIL"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="project" value="InterPro"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="entry name" value="Ribosomal_S8_B"/>
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    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="130" mass="14039" checksum="8CEC22E11A01B483" modified="2016-02-17" version="1">MTDPIADMLVRIKNAAAVRKQTVKMPSSKVKVAIAAVLKEEGYILDSRVTPTSAGKSELEISLKYYEGKPVIERLERYSRSGLRQYRGKDALPKVLGGLGVAIISTSKGIMTDAQARQQGVGGEVLCFVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKT8</accession>
    <name>A0A0S2DKT8_LYSEN</name>
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        <submittedName>
            <fullName evidence="1">Rhs family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3721</name>
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    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3721"/>
    <dbReference type="EnsemblBacteria" id="ALN59065">
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        <property type="gene ID" value="GLE_3721"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3721"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3666"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="894" mass="92696" checksum="7EBD40F08771EAB8" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKW4</accession>
    <name>A0A0S2DKW4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sulfotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_17655</name>
        <name evidence="3" type="ORF">GLE_3583</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
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    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3583"/>
    <dbReference type="EnsemblBacteria" id="ALN58927">
        <property type="protein sequence ID" value="ALN58927"/>
        <property type="gene ID" value="GLE_3583"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3583"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3527"/>
    <dbReference type="OMA" id="DLEHLLW"/>
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    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
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    </dbReference>
    <dbReference type="GO" id="GO:0008476">
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="268" mass="29990" checksum="6ED0DD75275E1189" modified="2016-02-17" version="1">MDRTTATPAPSRLVASPVFVISAVRSGSTLLRCVLDTHSRICAPHELHLPDFQVQLDTLQANVSMEAMGLDLAEVEHLLWDRMLHRLLDASGKHTIVDKTPANALRWQRLAQCWPQARFIFLVRHPSHVLDSMLAAAKGALGQELKERFGEQNERWGNPDSAQTMLLPQLSGVIQARAALPGLTVRYEELTADPARVTQDICRFLGLEWEPEMMEYGRVDHGPFKVFLGDNSERIHSGRIQASRELPAGDSVPPRLREVCQSLGYLPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL62</accession>
    <name>A0A0S2DL62_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
    <gene>
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    </gene>
    <organism evidence="2 3">
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        <lineage>
            <taxon>Bacteria</taxon>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59069">
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        <property type="gene ID" value="GLE_3725"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="50" mass="5345" checksum="A478797C71A38D38" modified="2016-02-17" version="1">MSQPQAPSKSRPPPVGAAQAATASTQLCRRFIRARSTTAALFAMLLRLSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLE9</accession>
    <name>A0A0S2DLE9_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">Regulatory protein, FmdB family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4071</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="69.GLE_4071"/>
    <dbReference type="EnsemblBacteria" id="ALN59413">
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        <property type="gene ID" value="GLE_4071"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4071"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4013"/>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="110" mass="11275" checksum="B4892A4153502D14" modified="2016-02-17" version="1">MPIYAFQCNACGHTFDRLQKLSDPDPTVCPECGAEQVGRQLTAPQFRLAGGGWYETDFKKDGDKKRNLAGEGGSGGAVTAKPAEAKTEKKADPAPAAAPAPASKPAAGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLK1</accession>
    <name>A0A0S2DLK1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ester cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_20295</name>
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    </gene>
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        <lineage>
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    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW27631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4140"/>
    <dbReference type="EnsemblBacteria" id="ALN59482">
        <property type="protein sequence ID" value="ALN59482"/>
        <property type="gene ID" value="GLE_4140"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4140"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4082"/>
    <dbReference type="OMA" id="FCTVAHW"/>
    <dbReference type="OrthoDB" id="1907687at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030638">
        <property type="term" value="P:polyketide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009959">
        <property type="entry name" value="Cyclase_SnoaL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38436">
        <property type="entry name" value="PTHR38436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07366">
        <property type="entry name" value="SnoaL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="199" mass="21915" checksum="85B3B3127DB1D5C6" modified="2016-02-17" version="1">MRAIGPFRPVPRGAALPLVVLIAAAVAGCARPQPAQVPLTAARADAAVLKRLQAEQAQQDRNLQTFDELDFVHYSGQQWDHFHRSHAQNILVHYPDGSTTTGLDAHLAALKPQFEFAPDTRIKLHPIKVAQGNLTAVTGVMEGTFTRPMALADGKTLAPTHKPFKLDMATFGRWENGVMVEEWLFWDNQAFMQQIGAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLQ9</accession>
    <name>A0A0S2DLQ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59527">
        <property type="protein sequence ID" value="ALN59527"/>
        <property type="gene ID" value="GLE_4185"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4185"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4127"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="62" mass="6559" checksum="2A7422D097BED6FC" modified="2016-02-17" version="1">MPSGRNGSPAAIACSRSTPKSERLKGSKRSLSASRPAGKTRQRIPPHTPALSQRRSFSSDGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLX4</accession>
    <name>A0A0S2DLX4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">General secretion pathway protein I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_4178</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GSP I family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4178"/>
    <dbReference type="EnsemblBacteria" id="ALN59520">
        <property type="protein sequence ID" value="ALN59520"/>
        <property type="gene ID" value="GLE_4178"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4178"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4120"/>
    <dbReference type="OMA" id="WRTTILP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010052">
        <property type="entry name" value="T2SS_protein-GspI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38779">
        <property type="entry name" value="PTHR38779"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="158" mass="17148" checksum="50E76B5C9F6398A1" modified="2016-02-17" version="1">MSARAFAPRSPRRARGCVRGARQRGYTLLEVIVAFALLAMALTLLLGSLSGAAKQVRWSSDAGRAALYAQSLMDQVGVGQPVRPGQRSGEFENGRYRWTLGIAPWRDSQLPASNQPIDPNAMRLFEVQLAVEWGEGGGGRRLLLRTLRSGNAGNEAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLZ8</accession>
    <name>A0A0S2DLZ8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">CoA transferase subunit B</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Succinyl-CoA--3-ketoacid-CoA transferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Succinyl-CoA:3-ketoacid-coenzyme A transferase, subunit B</fullName>
            <ecNumber evidence="3">2.8.3.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">scoB</name>
        <name evidence="4" type="ORF">BV903_04350</name>
        <name evidence="5" type="ORF">FE772_20700</name>
        <name evidence="3" type="ORF">GLE_4227</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 3-oxoacid CoA-transferase subunit B family.</text>
    </comment>
    <dbReference type="EC" id="2.8.3.5" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000008">
        <property type="protein sequence ID" value="OPD65156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948883.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000008.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4227"/>
    <dbReference type="EnsemblBacteria" id="ALN59568">
        <property type="protein sequence ID" value="ALN59568"/>
        <property type="gene ID" value="GLE_4227"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65156">
        <property type="protein sequence ID" value="OPD65156"/>
        <property type="gene ID" value="BV903_04350"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4227"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4168"/>
    <dbReference type="OMA" id="VAMMHTN"/>
    <dbReference type="OrthoDB" id="1380130at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008260">
        <property type="term" value="F:3-oxoacid CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012791">
        <property type="entry name" value="3-oxoacid_CoA-transf_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004165">
        <property type="entry name" value="CoA_trans_fam_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004164">
        <property type="entry name" value="CoA_transf_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13707">
        <property type="entry name" value="PTHR13707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01144">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00882">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02428">
        <property type="entry name" value="pcaJ_scoB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01274">
        <property type="entry name" value="COA_TRANSF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD65156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW27696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="210" mass="22270" checksum="1162D208E64BDA64" modified="2016-02-17" version="1">MPWTRDEMAQRAAQELTDGAYVNLGIGLPTLVANFIPDGMDVWLQSENGLLGIGPFPTEDEVDADLINAGKQTVTARAGASYFGSHDSFAMIRGGHIDLAILGAMQVTHQGDLANWMVPGKMVKGMGGAMDLVAGVKRVVVLMEHTAKNGEHKILPECTLPLTGLGVVNRIITELAVMDVTADGLVLVETAPGVGEDELREKTGVPLRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM35</accession>
    <name>A0A0S2DM35_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Valine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Valyl-tRNA synthetase</fullName>
            <shortName evidence="8">ValRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 13" type="primary">valS</name>
        <name evidence="14" type="ORF">FE772_20580</name>
        <name evidence="13" type="ORF">GLE_4197</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">C3</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val)</text>
            <dbReference type="Rhea" id="RHEA:10704"/>
            <dbReference type="Rhea" id="RHEA-COMP:9672"/>
            <dbReference type="Rhea" id="RHEA-COMP:9708"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78537"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.9"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The C-terminal coiled-coil domain is crucial for aminoacylation activity.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.9" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948863.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4197"/>
    <dbReference type="EnsemblBacteria" id="ALN59539">
        <property type="protein sequence ID" value="ALN59539"/>
        <property type="gene ID" value="GLE_4197"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4197"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4139"/>
    <dbReference type="OMA" id="FATKLWN"/>
    <dbReference type="OrthoDB" id="32262at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004832">
        <property type="term" value="F:valine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006438">
        <property type="term" value="P:valyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07962">
        <property type="entry name" value="Anticodon_Ia_Val"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02004">
        <property type="entry name" value="Val_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033705">
        <property type="entry name" value="Anticodon_Ia_Val"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019499">
        <property type="entry name" value="Val-tRNA_synth_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002303">
        <property type="entry name" value="Valyl-tRNA_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946">
        <property type="entry name" value="PTHR11946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10458">
        <property type="entry name" value="Val_tRNA-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00986">
        <property type="entry name" value="TRNASYNTHVAL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00422">
        <property type="entry name" value="valS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="10">
        <location>
            <begin position="16"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="11">
        <location>
            <begin position="646"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="domain" description="Val_tRNA-synt_C" evidence="12">
        <location>
            <begin position="857"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="528"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="531"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF10458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN59539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW27675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="921" mass="103263" checksum="8907455DF6A6E544" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM44</accession>
    <name>A0A0S2DM44_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA large subunit methyltransferase M</fullName>
            <ecNumber evidence="6">2.1.1.186</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">23S rRNA (cytidine2498-2'-O)-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">23S rRNA 2'-O-ribose methyltransferase RlmM</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">mtfA</name>
        <name evidence="6 12" type="synonym">rlmM</name>
        <name evidence="12" type="ORF">FE772_19145</name>
        <name evidence="11" type="ORF">GLE_3897</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(2498) in 23S rRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(2498) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42788"/>
            <dbReference type="Rhea" id="RHEA-COMP:10244"/>
            <dbReference type="Rhea" id="RHEA-COMP:10245"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.186"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.186" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948630.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3897"/>
    <dbReference type="EnsemblBacteria" id="ALN59240">
        <property type="protein sequence ID" value="ALN59240"/>
        <property type="gene ID" value="GLE_3897"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3897"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3835"/>
    <dbReference type="OMA" id="PVDWMVC"/>
    <dbReference type="OrthoDB" id="902245at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01551">
        <property type="entry name" value="23SrRNA_methyltr_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040739">
        <property type="entry name" value="RlmM_FDX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011224">
        <property type="entry name" value="rRNA_MeTrfase_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18125">
        <property type="entry name" value="RlmM_FDX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028774">
        <property type="entry name" value="UCP028774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6 8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RlmM_FDX" evidence="10">
        <location>
            <begin position="5"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="FtsJ" evidence="9">
        <location>
            <begin position="187"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="6 8">
        <location>
            <begin position="222"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6 7">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR028774-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR028774-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF18125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN59240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW27438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="352" mass="39486" checksum="1428EE8930D8DB86" modified="2016-02-17" version="1">MTDSALFCLCRAGFEPELAAELSERAANAGHPGYARTQRNSGYVEFVVEDAAAASRALPWSALIFARQKLVRLADLSGLDPSDRIAPILAALDAYGEPVAFGELWVEHPDSDEGKPLAGLARSFGNALRPALRKAGWLSKHDDPRKPRLHVVFLAGDHAVLAQADPDDGAPWPLGIPRLKMHPDAPSRSALKLEEALLTLLTPDERERRVRDNMQAADLGAAPGGWTWVLMRNGMKVTSVDNGPLRQALLDSGRVDHLRADGFTWQPKRTLDWMVCDMVESPARVAERMATWFRENWCRQAIFNLKLPMKKRWEETRVCLEAFEYQTHRPMIVRARQLYHDREEITVFAAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM46</accession>
    <name>A0A0S2DM46_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha-ketoacid dehydrogenase subunit beta</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Pyruvate dehydrogenase E1 component, beta subunit</fullName>
            <ecNumber evidence="3">1.2.4.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pdhB</name>
        <name evidence="4" type="ORF">FE772_21110</name>
        <name evidence="3" type="ORF">GLE_4317</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.2.4.1" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948956.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4317"/>
    <dbReference type="EnsemblBacteria" id="ALN59658">
        <property type="protein sequence ID" value="ALN59658"/>
        <property type="gene ID" value="GLE_4317"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4317"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4256"/>
    <dbReference type="OMA" id="LPLDTCF"/>
    <dbReference type="OrthoDB" id="900125at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Transket_pyr" evidence="2">
        <location>
            <begin position="21"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="343" mass="36818" checksum="4C301AF061DF23FD" modified="2016-02-17" version="1">MNAATQSKIETAQTAATPAAITLIEAITQALAYEMRNDPSVLVLGEDVGVNGGVFRATAGLQQIFGSERVLDTPLDETTIAGLSVGLAAQGMKPVAEAQFDGFVYPMLDHLICHAARLRHRTRGRLSCPLVLRVPWGGGIRAPEHHSEANESLFTNVPGLRVVLPSSPARAYGLLLAAIRDPDPVIFYEPKRIYRQYKEIVADDGEALPLDVCYVLRDGSDITLVSWGAQVKETLEAADKLAGEGISAEVIDVATLKPLDFATIAESVAKTGRCVIVHEAPKTAGFGAEIAARLAEESMYDLLAPVERVTGFDTHIPLFRLEMKYLPSVDKIVAAAKRALGHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM96</accession>
    <name>A0A0S2DM96_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidoglycan D,D-transpeptidase MrdA</fullName>
            <ecNumber evidence="3">3.4.16.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Penicillin-binding protein 2</fullName>
            <shortName evidence="3">PBP-2</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 8" type="primary">mrdA</name>
        <name evidence="8" type="ORF">FE772_22030</name>
        <name evidence="7" type="ORF">GLE_4510</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes cross-linking of the peptidoglycan cell wall.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the transpeptidase family. MrdA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.4" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4510"/>
    <dbReference type="EnsemblBacteria" id="ALN59851">
        <property type="protein sequence ID" value="ALN59851"/>
        <property type="gene ID" value="GLE_4510"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4510"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4446"/>
    <dbReference type="OMA" id="TLACKTG"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02081">
        <property type="entry name" value="MrdA_transpept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005311">
        <property type="entry name" value="PBP_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036138">
        <property type="entry name" value="PBP_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017790">
        <property type="entry name" value="Penicillin-binding_protein_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03717">
        <property type="entry name" value="PBP_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56519">
        <property type="entry name" value="SSF56519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03423">
        <property type="entry name" value="pbp2_mrdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3 8" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="3" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_dimer" evidence="6">
        <location>
            <begin position="73"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="5">
        <location>
            <begin position="274"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="707"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="3">
        <location>
            <position position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW27923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="753" mass="81497" checksum="6A57EC1292D345BC" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMK2</accession>
    <name>A0A0S2DMK2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyl-CoA desaturase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Fatty acid desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_21450</name>
        <name evidence="3" type="ORF">GLE_4391</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949014.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4391"/>
    <dbReference type="EnsemblBacteria" id="ALN59732">
        <property type="protein sequence ID" value="ALN59732"/>
        <property type="gene ID" value="GLE_4391"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4391"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4330"/>
    <dbReference type="OMA" id="HQVEHHI"/>
    <dbReference type="OrthoDB" id="1032884at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353">
        <property type="entry name" value="PTHR19353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="FA_desaturase" evidence="2">
        <location>
            <begin position="72"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="381" mass="43848" checksum="022A5C53686CCBAB" modified="2016-02-17" version="1">MSKQRNRALSAQELDRFGEELDALRARTLAQVGKVDADYIRRVVAAVRWTGLAGRALLYVGAIGGAFVSWLLWPACVLGALLLAASKIMENMEVGHNVMHGQYDWMRDPHLDGRSYEWDIVATGDNWRKTHNYQHHTWTNVRGMDDDIGYGLLRIFPEQRWRPFYLLQPPIAVVFALLFQWGVAIQELRVGRWLAGKTTHRAMWRKFVPVGRKMGKQLFKDYVLFPLLAGPFFLPVLLGNLVANGIRNVWTYVVIFCGHFTHDVEVFPKESVRNESRGHWYLRQLRGSANLTGGKAMNLMTGNLSHQIEHHFYPDIPAWRYASMAVEVREICARYGQHYDTGSLPRQFAEVSWRIVRHAFPSRPRKRRPLVRAETLAEAQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMS8</accession>
    <name>A0A0S2DMS8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADH dehydrogenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">SDR family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_22115</name>
        <name evidence="4" type="ORF">GLE_4529</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4529"/>
    <dbReference type="EnsemblBacteria" id="ALN59870">
        <property type="protein sequence ID" value="ALN59870"/>
        <property type="gene ID" value="GLE_4529"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4529"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4465"/>
    <dbReference type="OMA" id="QERWFAK"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025695">
        <property type="entry name" value="DoxX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13781">
        <property type="entry name" value="DoxX_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="326"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="398"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="427"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="Epimerase" evidence="3">
        <location>
            <begin position="25"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW27938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="447" mass="47374" checksum="2DC418CD177BDE3D" modified="2016-02-17" version="1">MDDPAPARAPRTDAAPPHSASPRTVLVVGANGFLAGYLIAALRRHGWRVLRGIRDGGRALREDERPADLARMTSPQDWRETLRGVDAVVNAAGILRETGAQTFQAIHVDGPLALARACADCGVPRFVQLSALGEPADGEFIASKHRFDDELLKLPLSAVALRPSVVYAASGSYGGTSLLRALAAFPGRQLLPGDGRWPLQPVAAEDLGEIAARAAGGAQSGVYEIGGPAPLSLREYQSTWRRWLRIDGRGAVFFPEALVSLQVAIGERLGRGPVGETMWRMLRRGNIARADAHARVRADFGHAPAALADALAATPSQVQDRWQAQLYFLAPTLRLAIVALWLISAAAGWLTPAATIEAMVAGSPLAAWQPVALARITGALDAALALGLLIGWRPRAMLGLMGISVLAYTLAFGALLPAQWLDPLGGLAKNLVVLPALAVAWVLADRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN64</accession>
    <name>A0A0S2DN64_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_22020</name>
        <name evidence="1" type="ORF">GLE_4508</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949108.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59849">
        <property type="protein sequence ID" value="ALN59849"/>
        <property type="gene ID" value="GLE_4508"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4508"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4444"/>
    <dbReference type="OrthoDB" id="1807602at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="140" mass="15976" checksum="D800EAEC3AF44BE1" modified="2016-02-17" version="1">MGCDIDLYAERRDNEGLYRPLSTSGLLSHRNYWRFSFLAGIRNSFNVVPISEPRGLPVDVSREIAAECERQEGDAVAQSWLSLEELLAFDYDAPLRFREGGRGDNCAEATYREFLDADFVSELRELQALGAERIVFWFDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN84</accession>
    <name>A0A0S2DN84_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4616</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949184.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4616"/>
    <dbReference type="EnsemblBacteria" id="ALN59957">
        <property type="protein sequence ID" value="ALN59957"/>
        <property type="gene ID" value="GLE_4616"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4616"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4551"/>
    <dbReference type="OrthoDB" id="538762at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="408" mass="43087" checksum="AFFC95E5E5CE059D" modified="2016-02-17" version="1">MLLGRPPALRSLYVYPWDVASQGAREFAAQALGLGLTAATVALGGRAGKFVAAQHRGSRVVFAEEGTVCFEPDPRGYGEIAPVAHSDPALRHAVEDLAADGRLQLRAKLPLLHNARLAAQHPLHVVRNAWGDAYAHHLCPSSPAALEYALALSADCARLPLRGLVLEAPNWLSYAHGHAREFAQAHGNLWLEALLSLCFCSHCRQRAGAANVDADALAARVRARVDAYLAAPVDAAADQAAAWLLADLLEMPQLAAYLRLRHERVAEAVAAIRARLPRDRDVWAIATTRRPSANAWLEGSPLAALARACDGVEVRFDHADAARVAADAFDAVQRVGDPARVRAILRPGPPELGDGAALAAALAALQTAGIGDVAFYHYGRLRPHQLHALGAALRAGSAGAAHPSAGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN97</accession>
    <name>A0A0S2DN97_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Proline racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4612</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proline racemase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949181.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4612"/>
    <dbReference type="EnsemblBacteria" id="ALN59953">
        <property type="protein sequence ID" value="ALN59953"/>
        <property type="gene ID" value="GLE_4612"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4612"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4547"/>
    <dbReference type="OMA" id="SHVLWTG"/>
    <dbReference type="OrthoDB" id="559014at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008794">
        <property type="entry name" value="Pro_racemase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33442">
        <property type="entry name" value="PTHR33442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05544">
        <property type="entry name" value="Pro_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029792">
        <property type="entry name" value="Pro_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00028">
        <property type="entry name" value="Proline_Racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="312" mass="32845" checksum="DDFEE44879E1626E" modified="2016-02-17" version="1">MHSLDIIDSHTGGEPTRVVVAGFPDLGGGSLAEQRRRFGERYDGWRSAIACEPRGSDTVVGALLLPPQSPGACAGTIFFNNVGTLGMCGHGTIGLVRTLQFLGRIEPGEHRIDTPVGTVGARLHDDGRVSVDNVESWRHAAQVRLDVPGYGAVCGDVAWGGNWFFIVKVARVIALTHVRELSAFAEAIRTALEAAGVRGADGAQIDHIELETASTTPGIDGRNFVLCPGLAYDRSPCGTGTSAKLACLAADGKLAPGALWRQESVLGSVFEGSYRSGERGVHPTITGSAHITARAQLLIDETDPFAWGIGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNC9</accession>
    <name>A0A0S2DNC9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar basal body protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">flgE</name>
        <name evidence="9" type="ORF">BV903_14305</name>
        <name evidence="10" type="ORF">FE772_22635</name>
        <name evidence="8" type="ORF">GLE_4644</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000036">
        <property type="protein sequence ID" value="OPD63299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949208.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4644"/>
    <dbReference type="EnsemblBacteria" id="ALN59985">
        <property type="protein sequence ID" value="ALN59985"/>
        <property type="gene ID" value="GLE_4644"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63299">
        <property type="protein sequence ID" value="OPD63299"/>
        <property type="gene ID" value="BV903_14305"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4644"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4580"/>
    <dbReference type="OMA" id="GLQNHQT"/>
    <dbReference type="OrthoDB" id="704242at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.98.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037058">
        <property type="entry name" value="Falgellar_hook_FlgE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019776">
        <property type="entry name" value="Flagellar_basal_body_rod_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020013">
        <property type="entry name" value="Flagellar_FlgE/F/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037925">
        <property type="entry name" value="FlgE/F/G-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117143">
        <property type="entry name" value="SSF117143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03506">
        <property type="entry name" value="FlgEFG_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00588">
        <property type="entry name" value="FLAGELLA_BB_ROD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="6">
        <location>
            <begin position="5"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="7">
        <location>
            <begin position="339"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD63299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW28023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="419" mass="44393" checksum="87941564E79715F5" modified="2016-02-17" version="1">MLDSIYIGMSGLTAHSKGLQTISNNVANLNTPGFKTTTPRFSDLYYGQRFFGQGPDSARVASGGSGVEYGYGALNFKQGEIRRSDGQLDLGIDGPGFLALLQDGKVRYARTGQFVIDDDGIVREKGSKMELTTLGADGKLANILIDKLRTSSAKPTATVKIEGRLQSNVNPNQPGSGNNPPTGTAPETFSIANVEMYDASGTKIVTTVKITRDLISPPLGNNSARWQVALIDKDNKTIGQGEIRFINSTIEPGADKVAIRVTSGNGMTSEVTLDFANIAYVFGPTVNSDLKVAKTDGYGPGTMSGMRVDDTGALVIDYSNGQKETLGKIAMADFADPQRLIQLGDGVFDASQLPDPAYVASKQGAGTLSSGAIEASNVDLSTEFGRLILIQRGFQASSQVISTANEMIMQLFQMKSGQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNG6</accession>
    <name>A0A0S2DNG6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4498</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4498"/>
    <dbReference type="EnsemblBacteria" id="ALN59839">
        <property type="protein sequence ID" value="ALN59839"/>
        <property type="gene ID" value="GLE_4498"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4498"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4434"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595026" evidence="1">
        <location>
            <begin position="21"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="294" mass="31626" checksum="22E94A6FFFF0A3BF" modified="2016-02-17" version="1">MKILTPFCLLLALASSAATAATPTTSFYAVGHQDDWQLFMNPNAFNDVRETTARTVIVHTTAGDAGVGTGNAGRSQPYYLAREEGALRALRFMKSAYRDVGQQQLQRTVPTINGHPIVRYASTDGRAVMYFLRLPDGGVGGSQSIALLKTAGTPVSAIDGSTTYSTWANFTATLAALVRAEASGSIDVWFNLADTDATLNPGDHTDHVYTSQAMQEARAALSTCINQALYVEYDTKNRPDNVGGNNLLTKVATWGATNSGIADMDHANSFDNDHNPWLTRTYYRVLNGTGDCAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNH5</accession>
    <name>A0A0S2DNH5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">RNA 3'-terminal phosphate cyclase</fullName>
            <shortName evidence="2">RNA cyclase</shortName>
            <shortName evidence="2">RNA-3'-phosphate cyclase</shortName>
            <ecNumber evidence="2">6.5.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 4" type="primary">rtcA</name>
        <name evidence="4" type="ORF">GLE_4347</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 3'-end 3'-phospho-ribonucleotide-RNA + ATP = a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23976"/>
            <dbReference type="Rhea" id="RHEA-COMP:10463"/>
            <dbReference type="Rhea" id="RHEA-COMP:10464"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:83062"/>
            <dbReference type="ChEBI" id="CHEBI:83064"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.5.1.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.4" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4347"/>
    <dbReference type="EnsemblBacteria" id="ALN59688">
        <property type="protein sequence ID" value="ALN59688"/>
        <property type="gene ID" value="GLE_4347"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4347"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4286"/>
    <dbReference type="OMA" id="PKPGLSH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003963">
        <property type="term" value="F:RNA-3'-phosphate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00200">
        <property type="entry name" value="RTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023797">
        <property type="entry name" value="RNA3'_phos_cyclase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037136">
        <property type="entry name" value="RNA3'_phos_cyclase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000228">
        <property type="entry name" value="RNA3'_term_phos_cyc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017770">
        <property type="entry name" value="RNA3'_term_phos_cyc_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020719">
        <property type="entry name" value="RNA3'_term_phos_cycl-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036553">
        <property type="entry name" value="RPTC_insert"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11096">
        <property type="entry name" value="PTHR11096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11096:SF0">
        <property type="entry name" value="PTHR11096:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01137">
        <property type="entry name" value="RTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005378">
        <property type="entry name" value="RNA3'_term_phos_cycl_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52913">
        <property type="entry name" value="SSF52913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="SSF55205"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03399">
        <property type="entry name" value="RNA_3prim_cycl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01287">
        <property type="entry name" value="RTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RTC" evidence="3">
        <location>
            <begin position="14"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-AMP-histidine intermediate" evidence="2">
        <location>
            <position position="312"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="287"/>
            <end position="291"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00021428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="344" mass="36390" checksum="369B9277FA14EB18" modified="2016-02-17" version="1">MDKKMEMIEISGATGGGQLLRTALALSLCTGTAFEMQHIRAKRKRPGLMRQHLTAVGAAAQIGRAYVEGAQLGATTLRFVPGQVQPGRYRFSIGTAGSATLVLQTVLPALWACDAASEITVEGGTHNPLAPSADFLAECYLPALRRFGVETAFALHRHGFFPAGGGCVQLRVAPGAALRPASFLERDPAPRLQATALLASLADAIGQRELQVLAGQLKLGPDALQLRRAPTAQSPANVLMLKIGGEGQHTELFDALGERGVGAEQVAAGLARRVGEYLSADAAVGEHLSDQLLLPMALAGGGEFTTAFVSDHLSSNARLIEKFLPVEIDWVQQGKRCWRVTVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNH9</accession>
    <name>A0A0S2DNH9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dihydrodipicolinate synthase family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Dihydrodipicolinate synthetase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_22480</name>
        <name evidence="2" type="ORF">GLE_4608</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DapA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949178.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4608"/>
    <dbReference type="EnsemblBacteria" id="ALN59949">
        <property type="protein sequence ID" value="ALN59949"/>
        <property type="gene ID" value="GLE_4608"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4608"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4543"/>
    <dbReference type="OMA" id="QAIKLSM"/>
    <dbReference type="OrthoDB" id="1438588at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="PTHR12128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="301" mass="31998" checksum="C3ABF281C5635393" modified="2016-02-17" version="1">MSTASIWRGVIPAITTPFHADGAIDHDFLARHARELIDAGCTGIVPLGSLGEAATLSFDDKLAILRTLVAALDGRAPVIPGIAALSTAEAVRLAQEAKKIGCAGLMVLPPYVYSTDWREMKAHVAAVIAATDLPCMIYNNPVAYKTDFSPEQIAELAGEFANVQAVKESSADVRRFAALRALLGDRLELLVGMDDAIVEGVAMGATGWIAGLVNAYPKESVRLFELARDGGAPAAAALYAWFLPLLRLDTVPKFVQLIKLVQAQVGMGAEHVRAPRLPVTGAEREAALAVIERAQAQRPEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNJ2</accession>
    <name>A0A0S2DNJ2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Flagellar biosynthetic protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Flagellar biosynthetic protein FliQ</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="10">Flagellar type III secretion system protein FliQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fliQ</name>
        <name evidence="9" type="ORF">BV903_14210</name>
        <name evidence="10" type="ORF">FE772_22550</name>
        <name evidence="8" type="ORF">GLE_4624</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FliQ/MopD/SpaQ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000036">
        <property type="protein sequence ID" value="OPD63281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949191.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4624"/>
    <dbReference type="EnsemblBacteria" id="ALN59965">
        <property type="protein sequence ID" value="ALN59965"/>
        <property type="gene ID" value="GLE_4624"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63281">
        <property type="protein sequence ID" value="OPD63281"/>
        <property type="gene ID" value="BV903_14210"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4624"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4560"/>
    <dbReference type="OMA" id="MVQAATS"/>
    <dbReference type="OrthoDB" id="1939288at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002191">
        <property type="entry name" value="Bac_export_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34040">
        <property type="entry name" value="PTHR34040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01313">
        <property type="entry name" value="Bac_export_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004669">
        <property type="entry name" value="FliQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00952">
        <property type="entry name" value="TYPE3IMQPROT"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD63281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW28009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="88" mass="9506" checksum="6135416E871C6198" modified="2016-02-17" version="1">MSADQALQLMEQLFWNSFLIASPILIATLLVGVLISIVQVVTQLQEMSLSYVPKLGVAVVIVVVLGSWMLGRLTGFATELFKSIANLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNX9</accession>
    <name>A0A0S2DNX9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lrp/AsnC family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, AsnC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">D9T17_05980</name>
        <name evidence="6" type="ORF">FE772_22765</name>
        <name evidence="5" type="ORF">GLE_4674</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">OH11</strain>
        </source>
    </reference>
    <reference evidence="6 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 10">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000019">
        <property type="protein sequence ID" value="ROU07756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949229.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4674"/>
    <dbReference type="EnsemblBacteria" id="ALN60015">
        <property type="protein sequence ID" value="ALN60015"/>
        <property type="gene ID" value="GLE_4674"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4674"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4610"/>
    <dbReference type="OMA" id="MSEWIDN"/>
    <dbReference type="OrthoDB" id="1844486at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019885">
        <property type="entry name" value="Tscrpt_reg_HTH_AsnC-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13404">
        <property type="entry name" value="HTH_AsnC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00519">
        <property type="entry name" value="HTH_ASNC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="4"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW28043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROU07756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="144" mass="15745" checksum="2B03F91EEA8BF44A" modified="2016-02-17" version="1">MKTLDEIDRKLIALLQDNARLSTVALAKAVALSRSTVQERLQRLEASGTIAQYTVRLGSGGDPLRAWLLLRYAEGFSCDDVVPLLAPLPQVRLAHSVVGDTDLMVLVETRSPGELADLRERVMGLKGVDDVTTVPVLRTVLDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP60</accession>
    <name>A0A0S2DP60_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4952</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4952"/>
    <dbReference type="EnsemblBacteria" id="ALN60293">
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        <property type="gene ID" value="GLE_4952"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4952"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4880"/>
    <dbReference type="OMA" id="DYAAWTR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595921" evidence="1">
        <location>
            <begin position="49"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="629" mass="69205" checksum="4AF589AA5882BD67" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP72</accession>
    <name>A0A0S2DP72_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_24455</name>
        <name evidence="2" type="ORF">GLE_5045</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949512.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5045"/>
    <dbReference type="EnsemblBacteria" id="ALN60386">
        <property type="protein sequence ID" value="ALN60386"/>
        <property type="gene ID" value="GLE_5045"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5045"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4973"/>
    <dbReference type="OMA" id="MITYEWS"/>
    <dbReference type="OrthoDB" id="2055010at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
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        <location>
            <begin position="4"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="169" mass="18726" checksum="063A0C4EE7041085" modified="2016-02-17" version="1">MTHLRIRDAAPADCDLIAQWMLAMAWETEQKRLDPATVHAGVGAGLADPAKARYFVAMREAQTAGHETIAVPAGTLMLTREWSDWRNGEWWWIQSVYVAAEHRRQGVYDALHSHVAALAQATPDVVGLRLYVERGNAAAQRTYRAQGMVDAGYDLFEQEFGAGERSAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP82</accession>
    <name>A0A0S2DP82_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="1 2">
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        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60185">
        <property type="protein sequence ID" value="ALN60185"/>
        <property type="gene ID" value="GLE_4844"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4844"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4774"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="73" mass="7771" checksum="FCAC149873DEE3C3" modified="2016-02-17" version="1">MLFRNGALRRAVFVCAPEAPVGAARAATATLRTPAQPVSGVSLPGCGGCRRRLRCRGRGLRRSYRTGMRDGAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPP6</accession>
    <name>A0A0S2DPP6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_24625</name>
        <name evidence="2" type="ORF">GLE_5080</name>
    </gene>
    <organism evidence="2 4">
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        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949540.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60421">
        <property type="protein sequence ID" value="ALN60421"/>
        <property type="gene ID" value="GLE_5080"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5080"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5007"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="133" mass="15024" checksum="0B83BD2783AD8F2C" modified="2016-02-17" version="1">MTLLHFPANRLRPRPRPGKAPYRAIAPLLRLACARLRERDAADARGALVATWWRSPQSGRLECRWTRAGAAEEPPGRERMDRRDRRDPSDRRSDRRAHRDAHPLRRSEACPDVPSLPAISAGAAARALVAQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPT6</accession>
    <name>A0A0S2DPT6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4291 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_25425</name>
        <name evidence="1" type="ORF">GLE_5255</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057950356.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5255"/>
    <dbReference type="EnsemblBacteria" id="ALN60596">
        <property type="protein sequence ID" value="ALN60596"/>
        <property type="gene ID" value="GLE_5255"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5255"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5174"/>
    <dbReference type="OMA" id="RDRMTWI"/>
    <dbReference type="OrthoDB" id="1352255at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025633">
        <property type="entry name" value="DUF4291"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38567">
        <property type="entry name" value="PTHR38567"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14124">
        <property type="entry name" value="DUF4291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="202" mass="23081" checksum="D0083C50461D3337" modified="2016-02-17" version="1">MGAGRDAAAQTASGVPYRQIRAVYDDATIRVYQAFNDPIADAALAAGRFVAPFSRSRMTWIKPSFRWMLYRAGWGFKDDNQRRILAIDIAREGFEWALANSCSSHPDPAMTPAQWQRHRDATPVRIQWDPERNLRLEPLDHRSIQIGLGRPAVLRYVQEWTQRIEDVTPLAHRVHELVRADRLDEAVALLPAERPYVPNTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ01</accession>
    <name>A0A0S2DQ01_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5470</name>
    </gene>
    <organism evidence="1 2">
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60811">
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        <property type="gene ID" value="GLE_5470"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5470"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5385"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="80" mass="8611" checksum="DE79BAD4F7F58138" modified="2016-02-17" version="1">MSLHASPIAAQCRCAAEVAGAHETLGRFCISKMGSTQVRSSRATVPARPAAWSMKRTSVVSKRSGGYRYVKPAQSRISEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-06-17" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ18</accession>
    <name>A0A0S2DQ18_LYSEN</name>
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            <fullName evidence="3">Diguanylate cyclase</fullName>
        </submittedName>
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        <name evidence="3" type="ORF">GLE_5222</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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            <strain evidence="3 5">C3</strain>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="entry name" value="MHYT_dom"/>
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        <property type="match status" value="3"/>
    </dbReference>
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        <property type="entry name" value="MHYT"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
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            <begin position="82"/>
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            <end position="136"/>
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    </feature>
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            <end position="237"/>
        </location>
    </feature>
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            <begin position="11"/>
            <end position="200"/>
        </location>
    </feature>
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            <dbReference type="PROSITE-ProRule" id="PRU00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="247" mass="25206" checksum="4CEA179A626190C0" modified="2016-02-17" version="1">MPLDHAIQCVHDPLLVILSYVVSVLGSFTALQLAIAIPGATGAARWRAVTAAGIAMGGGAIWAMHFIAMLACRMNVEVTYDLPLTLGSAVVAVVSCMAGLAIAGTGVFNWGKLILGGVLMGLGVTGMHYAGMAAMLMPADTVYNSTLVVASAAIAVVASIVALWLAFNLRGWGQMLGSALVMGVAVCGMHYTGMLAASFVPDKNAAAAGGVSGGYLGIGIFVVTTALLAAVLTISLLRQRQRAMVRI</sequence>
</entry>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">C3</strain>
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    </reference>
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    </dbReference>
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            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="364" mass="39732" checksum="D3C24EDBAD6FDB43" modified="2016-02-17" version="1">MSIVVSASPDFTRDDSNRHDSNQHDSTLPASAPHDSIARDSAARPHEPRHLATDPRSPDFIVFDPPLSLALVVSDVQPQPHEDDAGLLAALSEHGIHARPRIWSDPAVDWAGHDALLVRSTWDYFQRYTEFLQWYQRIDELRCPIANPLPLLVWNSDKRYLLDLAAQGVAIVATAHARGGELDAALASMQGEVVVKPSVSGGAWNTVRGRIGDAAFAEALAALPRELDYLIQPFLPQVVEDGEWSLLFFGGIYSHAVLKKPAQGDYRVQTYFGGRADLTEPLAPVLAAARRALDAVAALGHRDHAYVRVDGVVVDGALRIMELEFIEPFLHLAAHPPAARAFAAQLAQRWSGLRESRASAASPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQJ2</accession>
    <name>A0A0S2DQJ2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_00680</name>
        <name evidence="2" type="ORF">GLE_5493</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Gammaproteobacteria</taxon>
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    <reference evidence="2 4" key="1">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60834">
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        <property type="gene ID" value="GLE_5493"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5493"/>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
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            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="397" mass="45150" checksum="E0A832BA6A6A9BC4" modified="2016-02-17" version="1">MEEGELEWEKKIESLFQQAPHLRSLIEKPVYCSDAPWAGEVYSYFLKNTQGSTGEDFYRVVYKQGSPTSLMTIGSGELSGLKTTTVVERGRIADVAGLERVDIPAEINWLPMLLMMGIFGAVQRHVGYISNVCADIRNRQIVGDHAKLERISEVILDCFESIPEMDQNMMHLNLSRAVSNTDDCHELLIVMREELNKESQDNPRPPRTFDKWTPQPDNSSFNPVEFMRRMMRHNVFAAYERFVAGKICQIVLSRNYSPSNIKRSKDAAIRVKDTIRKIFEGRIKAHEEGVKEYGRLIFQLRNGYEIGGNWTISELEECRSSQELTIINIEKKLCELLDAKLESFDFLSRLSSRDEINVYLTKNVIVISEEKASAQPGQQEPVETDGSQVPAGMTPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQL3</accession>
    <name>A0A0S2DQL3_LYSEN</name>
    <protein>
        <submittedName>
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        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_25410</name>
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        </lineage>
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    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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        <property type="protein sequence ID" value="QCW28490.1"/>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5250"/>
    <dbReference type="EnsemblBacteria" id="ALN60591">
        <property type="protein sequence ID" value="ALN60591"/>
        <property type="gene ID" value="GLE_5250"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5250"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5169"/>
    <dbReference type="OMA" id="PDVLMTL"/>
    <dbReference type="OrthoDB" id="1654295at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HTH_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026881">
        <property type="entry name" value="WYL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08279">
        <property type="entry name" value="HTH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13280">
        <property type="entry name" value="WYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_11" evidence="1">
        <location>
            <begin position="6"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="WYL" evidence="2">
        <location>
            <begin position="138"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="234" mass="26098" checksum="9705BA1B2E24CFC6" modified="2016-02-17" version="1">MRRADRLFLLIHALRGRRQAITAQQLAQTLEVSLRTVYRDVADLQRSGVPIEGEAGVGYVLRKGADIPPLMFSPDELEALVVGTRFVRAFGGERLGRGATAALLKIEAVLPPELRERAARTRIFAPELAGRIESSGLIDALHAAVQEHRVLRLTYRDSGARASEREIEPLCLSFWGGSWTLGAWCRLREDFRSFRPDRIATHSATGEVFAADERRGLQAYLRSVGGALPDRWKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQN5</accession>
    <name>A0A0S2DQN5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_00825</name>
        <name evidence="1" type="ORF">GLE_5525</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949865.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5525"/>
    <dbReference type="EnsemblBacteria" id="ALN60866">
        <property type="protein sequence ID" value="ALN60866"/>
        <property type="gene ID" value="GLE_5525"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5525"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5440"/>
    <dbReference type="OMA" id="KTVEYRT"/>
    <dbReference type="OrthoDB" id="2067185at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="72" mass="8116" checksum="C79A9F58A2BC2959" modified="2016-02-17" version="1">MSDLPYTHEQLQALRSALARGERRVSFGDRLVEYRSVDELLAAIREVEAALAGTEGRPRKVRRLLTTTSKGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQP6</accession>
    <name>A0A0S2DQP6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Glucose-inhibited division protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 14" type="primary">gidA</name>
        <name evidence="11 15" type="synonym">mnmG</name>
        <name evidence="15" type="ORF">FE772_25230</name>
        <name evidence="14" type="ORF">GLE_5211</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">C3</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 11">NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9 11">Homodimer. Heterotetramer of two MnmE and two MnmG subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the MnmG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949638.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5211"/>
    <dbReference type="EnsemblBacteria" id="ALN60552">
        <property type="protein sequence ID" value="ALN60552"/>
        <property type="gene ID" value="GLE_5211"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5211"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5130"/>
    <dbReference type="OMA" id="FRPGYAI"/>
    <dbReference type="OrthoDB" id="146811at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00129">
        <property type="entry name" value="MnmG_GidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004416">
        <property type="entry name" value="MnmG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002218">
        <property type="entry name" value="MnmG-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020595">
        <property type="entry name" value="MnmG-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026904">
        <property type="entry name" value="MnmG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044920">
        <property type="entry name" value="MnmG_C_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040131">
        <property type="entry name" value="MnmG_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806">
        <property type="entry name" value="PTHR11806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806:SF0">
        <property type="entry name" value="PTHR11806:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01134">
        <property type="entry name" value="GIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13932">
        <property type="entry name" value="GIDA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00136">
        <property type="entry name" value="gidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01280">
        <property type="entry name" value="GIDA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01281">
        <property type="entry name" value="GIDA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8 11" id="KW-0520">NAD</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="GIDA" evidence="12">
        <location>
            <begin position="9"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="GIDA_C" evidence="13">
        <location>
            <begin position="404"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="14"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="274"/>
            <end position="288"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN60552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW28462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="629" mass="68301" checksum="B8C1C0A7926F6ECC" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAH9</accession>
    <name>A0A0S2DAH9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-binding response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Response regulator transcription factor</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BV903_22610</name>
        <name evidence="8" type="ORF">D9T17_01980</name>
        <name evidence="7" type="ORF">FE772_01680</name>
        <name evidence="5" type="ORF">GLE_0159</name>
    </gene>
    <organism evidence="5 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 9">C3</strain>
        </source>
    </reference>
    <reference evidence="6 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">OH11</strain>
        </source>
    </reference>
    <reference evidence="7 12" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 12">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000076">
        <property type="protein sequence ID" value="OPD61623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000006">
        <property type="protein sequence ID" value="ROU08881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945836.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0159"/>
    <dbReference type="EnsemblBacteria" id="ALN55518">
        <property type="protein sequence ID" value="ALN55518"/>
        <property type="gene ID" value="GLE_0159"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61623">
        <property type="protein sequence ID" value="OPD61623"/>
        <property type="gene ID" value="BV903_22610"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0159"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.161"/>
    <dbReference type="OMA" id="VYAMREK"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="143"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN55518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD61623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW24577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROU08881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="222" mass="23464" checksum="1155FC89A2ECD556" modified="2016-02-17" version="1">MPTLLIADDHPLFREALRGAVARVLPDAALREADSVDALYALVEAESDADLLLLDLNMPGAQGFSALVHLRALHPQLPIVVVSAREEPSTMRRALDHGAVGFIPKSADAATLGEAITTVLDGDRWAPPAAVAAPAANADEHEAAQRLRELTPQQFRVLQMLGAGLLNKQIGYELGVSEATVKAHVTAILRKLGANNRTQAVLIAGRLALDPGAIVPPPEEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAL5</accession>
    <name>A0A0S2DAL5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquinone biosynthesis accessory factor UbiK</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ubiK</name>
        <name evidence="3" type="ORF">BV903_12890</name>
        <name evidence="4" type="ORF">FE772_02015</name>
        <name evidence="2" type="ORF">GLE_0237</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UbiK family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000032">
        <property type="protein sequence ID" value="OPD63516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945892.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0237"/>
    <dbReference type="EnsemblBacteria" id="ALN55596">
        <property type="protein sequence ID" value="ALN55596"/>
        <property type="gene ID" value="GLE_0237"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63516">
        <property type="protein sequence ID" value="OPD63516"/>
        <property type="gene ID" value="BV903_12890"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0237"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.239"/>
    <dbReference type="OMA" id="IMIDLNH"/>
    <dbReference type="OrthoDB" id="1995361at2"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02216">
        <property type="entry name" value="UbiK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007475">
        <property type="entry name" value="UbiK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38040">
        <property type="entry name" value="PTHR38040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04380">
        <property type="entry name" value="BMFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="49"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="92" mass="10684" checksum="DBB27D418C01D845" modified="2016-02-17" version="1">MIDLNYIDDLARRLSTLVPPGVREGREEMQQNFKSVLQTGLSKLDLVTREEFEVQRAVLLRTREKLEELQRTVAELESRLDDASEPQHAPQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAR0</accession>
    <name>A0A0S2DAR0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bifunctional protein PutA</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="2">Proline dehydrogenase</fullName>
                <ecNumber evidence="2">1.5.5.2</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="2">Proline oxidase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="2">Delta-1-pyrroline-5-carboxylate dehydrogenase</fullName>
                <shortName evidence="2">P5C dehydrogenase</shortName>
                <ecNumber evidence="2">1.2.1.88</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="2">L-glutamate gamma-semialdehyde dehydrogenase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="10" type="primary">putA</name>
        <name evidence="10" type="ORF">GLE_0285</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Oxidizes proline to glutamate for use as a carbon and nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + L-glutamate 5-semialdehyde + NAD(+) = 2 H(+) + L-glutamate + NADH</text>
            <dbReference type="Rhea" id="RHEA:30235"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="EC" id="1.2.1.88"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a quinone + L-proline = (S)-1-pyrroline-5-carboxylate + a quinol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23784"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17388"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.5.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 1/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the proline dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.5.2" evidence="2"/>
    <dbReference type="EC" id="1.2.1.88" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0285"/>
    <dbReference type="EnsemblBacteria" id="ALN55643">
        <property type="protein sequence ID" value="ALN55643"/>
        <property type="gene ID" value="GLE_0285"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0285"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.284"/>
    <dbReference type="OMA" id="PPWNFPV"/>
    <dbReference type="UniPathway" id="UPA00261">
        <property type="reaction ID" value="UER00373"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003842">
        <property type="term" value="F:1-pyrroline-5-carboxylate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004657">
        <property type="term" value="F:proline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006561">
        <property type="term" value="P:proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:proline catabolic process to glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.550">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025703">
        <property type="entry name" value="Bifunct_PutA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005933">
        <property type="entry name" value="Delta1-pyrroline-5-COlate_DH-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041349">
        <property type="entry name" value="PRODH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024090">
        <property type="entry name" value="PRODH_PutA_dom_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024089">
        <property type="entry name" value="PRODH_PutA_dom_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024082">
        <property type="entry name" value="PRODH_PutA_dom_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002872">
        <property type="entry name" value="Proline_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01619">
        <property type="entry name" value="Pro_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14850">
        <property type="entry name" value="Pro_dh-DNA_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18327">
        <property type="entry name" value="PRODH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000197">
        <property type="entry name" value="Bifunct_PutA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="SSF51730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81935">
        <property type="entry name" value="SSF81935"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01238">
        <property type="entry name" value="D1pyr5carbox3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
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    <keyword evidence="2" id="KW-0678">Repressor</keyword>
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    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
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        <location>
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            <end position="83"/>
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            <end position="205"/>
        </location>
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        <source>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
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    <sequence length="1089" mass="116749" checksum="52A9A724F6104762" modified="2016-02-17" version="1"> </sequence>
</entry>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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    <sequence length="184" mass="19527" checksum="BF5C5CF28A62931C" modified="2016-02-17" version="1">MAIFFATALASCASGGGTKKSPNDYNALLRNAEAELSAGRMEQALVGFNAAAQADPTRKEPWLRSAQLQFDAGNYGRAIVAAEEALKRDPNDKIADSVLTVSGLRVASKSLNRLQSSGALVSDAAQKEARDLATTMRNTMGRDFVLGEESKPTPRPQPKPASSRPSKKPAKPAAAQPKDDNPFN</sequence>
</entry>
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        </source>
    </evidence>
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        <source>
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        </source>
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    <sequence length="104" mass="11736" checksum="45081C6DF13E13E1" modified="2016-02-17" version="1">MVPGRFNAFRFYFAAVLEYWYLRCGAWIEGKASTPAYPPDLADAMRWDGANPYAREAASPAQQAASRGDLDHFRRRWRIVAVLSTLLYGGIFVGMVAIGWLVFV</sequence>
</entry>
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    <accession>A0A0S2DBG7</accession>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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            <end position="170"/>
        </location>
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        </source>
    </evidence>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="234" mass="26269" checksum="AF1078310D0D5597" modified="2016-02-17" version="1">MGSNEAGTTVTALLRGRAVAYSRPGSVSAIDKRPLHGPVRIGELGLDGDEQGDLRVHGGPDKAVHHYPREHYRRWRDEIGPHALFDAPGAFGENLSSEGLDEAAVCLGDRYRFGEVLLEVSQARQPCWKLNDRFGVADMARRMQANGRTGWYYRVIEAGRAEAGERLHLIARPWPRWSLQRIATMLFVRTLDREELQAALALPLVPSWRKLVEARLARGQVEDWSKRIDGPSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBR3</accession>
    <name>A0A0S2DBR3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_03670</name>
        <name evidence="2" type="ORF">GLE_0597</name>
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        <lineage>
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    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55955.1"/>
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    </dbReference>
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        <property type="protein sequence ID" value="QCW24901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946150.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0597"/>
    <dbReference type="EnsemblBacteria" id="ALN55955">
        <property type="protein sequence ID" value="ALN55955"/>
        <property type="gene ID" value="GLE_0597"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0597"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.589"/>
    <dbReference type="OMA" id="DENEYRG"/>
    <dbReference type="OrthoDB" id="1869306at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726792" evidence="1">
        <location>
            <begin position="23"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="216" mass="23847" checksum="7030823F136B3EF4" modified="2016-02-17" version="1">MKTAILLAGLTVVAATALGLSACSNAVKDPKYERNPDPKRKYVVTVKVDGAPGPFRIVTAGVRYVVGPSQECMPAAEPISGTFPTPEHANLASQVRRVSESESEFEFDVYLDGMAAKDYFGRGVCTWRIESVTMSLKPTGADRERKFSTNIDEADVTGNASLVLYARREMYGASAENDYEIFEDALKKEWFSKRYGDDPSKFFTITFSARESGRDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBU3</accession>
    <name>A0A0S2DBU3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0626</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55984">
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        <property type="gene ID" value="GLE_0626"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="133" mass="14243" checksum="4ABF374E50263673" modified="2016-02-17" version="1">MAAHRDARIDARIDARIDARIDGPKALPAARGLRAVATRYGPACKAETGLLVDWRARGASPIGRPRQERHNPQLTQQKARERASPTQSMGCEASPRRCGGSRPYRSQARAPASREASAPQRCASSAVSVSTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCB1</accession>
    <name>A0A0S2DCB1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Threonine dehydratase catabolic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_0820</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946321.1">
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_0820"/>
    <dbReference type="EnsemblBacteria" id="ALN56178">
        <property type="protein sequence ID" value="ALN56178"/>
        <property type="gene ID" value="GLE_0820"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0820"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.809"/>
    <dbReference type="OMA" id="LIHPFDH"/>
    <dbReference type="OrthoDB" id="1876944at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="39"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="359"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="382" mass="40470" checksum="CB37EECA2302CC09" modified="2016-02-17" version="1">MDGDVVRNPVRAGAAARGPDVGAADLLAAQARLRRYLSVTPLHHAERFGCWLKLENLQRTGSYKVRGALNALLAARERGDHRPVIAASAGNHAQGLAWAAYRLGVNAITVMPRCAPQTKIAGVAHWGATVRLHGDTYDEAKAFAIELAQQHDYRLLSAFDDPDVIAGQGTVGLELAAFAPDVVLVPIGGGGLASGVALALKSQGVRIIGAQVEGVDSMARALRGDRRLIEPVATLADGVRVKDPGRLTERLLADLLDDVVIVREAELRETLVRLALEEHIIAEGAGALALAAGRRIAAKRKCAVVSGGNVDAGVLAQLLSEVRPRAPRRPRRRNRDTSLSRAGASIEVDIYQLANLPPPRAVAASARPSPSPHRTVTEDVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCB3</accession>
    <name>A0A0S2DCB3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cupin</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Cupin domain protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Cupin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_19965</name>
        <name evidence="5" type="ORF">FE772_04595</name>
        <name evidence="3" type="ORF">GLE_0780</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000059">
        <property type="protein sequence ID" value="OPD62161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946294.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000059.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0780"/>
    <dbReference type="EnsemblBacteria" id="ALN56138">
        <property type="protein sequence ID" value="ALN56138"/>
        <property type="gene ID" value="GLE_0780"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62161">
        <property type="protein sequence ID" value="OPD62161"/>
        <property type="gene ID" value="BV903_19965"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0780"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.769"/>
    <dbReference type="OMA" id="PKGVEHC"/>
    <dbReference type="OrthoDB" id="1928636at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="2">
        <location>
            <begin position="38"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD62161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="123" mass="13825" checksum="ED8087E296F91AC7" modified="2016-02-17" version="1">MSIASPARIAASLAELWSPRVVAEVDDAYVKVARVHGTLAWHSHADEDELFYVLKGRLRIEMESRTVELGEGELFVVPKGVRHNPVADEECHLLLIERKSTQHTGEEVTDKTRSLAEQLRPVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCG0</accession>
    <name>A0A0S2DCG0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hemolysin-type calcium-binding repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0845</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946340.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0845"/>
    <dbReference type="EnsemblBacteria" id="ALN56203">
        <property type="protein sequence ID" value="ALN56203"/>
        <property type="gene ID" value="GLE_0845"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0845"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.834"/>
    <dbReference type="OMA" id="LANAEHE"/>
    <dbReference type="OrthoDB" id="1560944at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028208">
        <property type="entry name" value="Effector_pro_NleD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14891">
        <property type="entry name" value="Peptidase_M91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="55"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="186"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="250"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="471"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="511" mass="52824" checksum="D29CCA90B51EB4AE" modified="2016-02-17" version="1">MSVQLDATRPAPPQADAYWDNPAASDPNRQVTPEPLTLLQTAAIEPTARLAADGTVEIDGSATNPQQRTQSSTPDGKPVQVDPLHDGTEVSIARERTLADAGGGRQYVSADQIVLTTGAKNDKVNVTQRDDGTLDVGVNGENYAVRLTENQELTIRSGDGDDTITVAPNVKVNIVVDAGAGDDTVTTGAGNDRVDGGLGNDRIGTGDGRDDVFGNSGDDVIDAGAGDDVVYGGDGADRLLGGAGTDFLEGGSGNDELDGGGGHDMLSGGLGDDALRGGEGDDAVYTGDGRDSVDNRSGNDTVYAQRAVDLINAASGARNTVVNVEIGAAKGVTIEGSDAFKQRVGAEIEFLRASPNGQRMLAEFDKAAARGNTVTIKELANEENGYAQTFSNDADIVNGRPGKGGDVQISYNPSFHMDAFPAPVGVLYHEMSHAYNGVTGTFQPGTYVGSGPDSGRVPNAERQAVGLETSAPAYDFDGDPATPKTTANPDHLTENGMRAELGLPDRPSYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCN6</accession>
    <name>A0A0S2DCN6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">LysR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_19690</name>
        <name evidence="5" type="ORF">FE772_05150</name>
        <name evidence="3" type="ORF">GLE_0897</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000057">
        <property type="protein sequence ID" value="OPD62214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946377.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000057.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0897"/>
    <dbReference type="EnsemblBacteria" id="ALN56255">
        <property type="protein sequence ID" value="ALN56255"/>
        <property type="gene ID" value="GLE_0897"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62214">
        <property type="protein sequence ID" value="OPD62214"/>
        <property type="gene ID" value="BV903_19690"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0897"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.886"/>
    <dbReference type="OMA" id="VWTARNE"/>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD62214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="298" mass="32601" checksum="D9A33E0BC2EC1BEA" modified="2016-02-17" version="1">MDLLRAMAVFVSVADTGSFAAAAQAQRLSAVMVGKHVRQLEERLGARLLQRDTRKQRLTEAGAAFLAEARQVLEQVRRAETVTERLGDGARPRGHLRVSAPLTLGTVAIAPLATAYLRAYPDVSLDLALEDRAADLIAEGYDAAIRIGPLPDSDHLVARPLRPYRMMVCAAPSYLRERGTPASPAELIGHSCLNHLLWHPNAGWRFASLGGEALRLHGRFASNHGEALRRAALDGCGIVLQPEVLLADDIAAGRLVPLFEDDLPPPRPVHLLYPRDRQPLPKLSRFIELVMETLGPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCS0</accession>
    <name>A0A0S2DCS0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0966</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56324">
        <property type="protein sequence ID" value="ALN56324"/>
        <property type="gene ID" value="GLE_0966"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0966"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.953"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="77" mass="8152" checksum="C9B465BECFEC8F87" modified="2016-02-17" version="1">MTQGNEGDHGRAGPDAGAPDCGSIRWLRPPPPRASRPAARVARTRRRSGTGVGRKAHLPVAAGLRARDFERGVSAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCZ6</accession>
    <name>A0A0S2DCZ6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946499.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56425">
        <property type="protein sequence ID" value="ALN56425"/>
        <property type="gene ID" value="GLE_1067"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1067"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1055"/>
    <dbReference type="OMA" id="WQRIAPR"/>
    <dbReference type="OrthoDB" id="2008718at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="309" mass="31977" checksum="74206503B2CA7934" modified="2016-02-17" version="1">MPEQSPTPSDWAGAFAALPAETPPAGGWTRLAERLAEQPVAAAAAAPASVAATARRSRQRWALAAMLAAALPLGLWLGLRAQRPAQGPVSEPLVRQAPPAAAPQRDAVTAPTRTDDGNQRIAASGQADGGNRSVAGTADRGRDSASEARPTPAPATADTTQPTRTATAERRLATAAKVVPQPRATAAAPSDATPSAAPDHVARASDDARFAAQLRELQAESAQLEALVAAARDERVASAAAAVMSADLDQRLRLIDTALIDGALPAVSRVALWRERVDSLRALAGVESTQRWFAARGGERYDGALVRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD08</accession>
    <name>A0A0S2DD08_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_03880</name>
        <name evidence="1" type="ORF">GLE_1063</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000007">
        <property type="protein sequence ID" value="OPD65241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946497.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1063"/>
    <dbReference type="EnsemblBacteria" id="ALN56421">
        <property type="protein sequence ID" value="ALN56421"/>
        <property type="gene ID" value="GLE_1063"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65241">
        <property type="protein sequence ID" value="OPD65241"/>
        <property type="gene ID" value="BV903_03880"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1063"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1052"/>
    <dbReference type="OMA" id="ESIWFFD"/>
    <dbReference type="OrthoDB" id="1708533at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD65241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="185" mass="19667" checksum="6296FC4484FB39B1" modified="2016-02-17" version="1">MRAAPASAFALLPQRGGARAALPAPERLAAVATVLCVHPRRQRDALDGWLAARSAQRLGDGGGEALRFCDAGGRECWRLYLLPDSDFLAWDDVAAAMPDAAAAIRPAVVPALARWWRRLRGGRRAQALRLRVLRDADGHCVLLADPAELSPLGLAQARRIAAGEGARLDECADACCCLASGVGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD10</accession>
    <name>A0A0S2DD10_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Ribokinase</fullName>
            <shortName evidence="10">RK</shortName>
            <ecNumber evidence="3 10">2.7.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rbsK</name>
        <name evidence="13" type="ORF">GLE_1054</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + D-ribose = ADP + D-ribose 5-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13697"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:47013"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="10">Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate metabolism; D-ribose degradation; D-ribose 5-phosphate from beta-D-ribopyranose: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the carbohydrate kinase pfkB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.15" evidence="3 10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946491.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1054"/>
    <dbReference type="EnsemblBacteria" id="ALN56412">
        <property type="protein sequence ID" value="ALN56412"/>
        <property type="gene ID" value="GLE_1054"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1054"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1043"/>
    <dbReference type="OMA" id="TFCGYFA"/>
    <dbReference type="OrthoDB" id="1030724at2"/>
    <dbReference type="UniPathway" id="UPA00916">
        <property type="reaction ID" value="UER00889"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004747">
        <property type="term" value="F:ribokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019303">
        <property type="term" value="P:D-ribose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01174">
        <property type="entry name" value="ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01987">
        <property type="entry name" value="Ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011877">
        <property type="entry name" value="D_ribokin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002139">
        <property type="entry name" value="Ribo/fructo_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00990">
        <property type="entry name" value="RIBOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 10" id="KW-0630">Potassium</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="12">
        <location>
            <begin position="9"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="17"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="44"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="233"/>
            <end position="238"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="272"/>
            <end position="273"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN56412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="326" mass="32802" checksum="2952A76CA91412F6" modified="2016-02-17" version="1">MSDSANKGRVVVVGSFNIDHVWALPALPRPGETLAGTYHTGPGGKGFNQATAAARAGAATAFVCALGDDAGGRLARELAAGDGLDLRALRSAEPTGTAGIYVDADGRNTIVIGPGANAELSPAFVGEHAAALDAAQVALTQLETPLESAIAAFARARDAGGSTLLNPAPADAVASDALWALTDIATPNETEFCAQLQRRGGDALDPDALAGLDDAALHAHCRRLLAHGSVVITLGKSGCFVSHANGALRGDAQAFYRVAAAAVKAIDTTGAGDAFNGALAAALARDPDAAFGEHVRYAVRFAGLSTERAGAAAAMPSDAELRARFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD48</accession>
    <name>A0A0S2DD48_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA polymerase sigma-E factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_1068</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1068"/>
    <dbReference type="EnsemblBacteria" id="ALN56426">
        <property type="protein sequence ID" value="ALN56426"/>
        <property type="gene ID" value="GLE_1068"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1068"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1056"/>
    <dbReference type="OMA" id="HEHADSE"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="4">
        <location>
            <begin position="31"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="5">
        <location>
            <begin position="126"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="98"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN56426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="188" mass="21166" checksum="3551F36C42CAF0E5" modified="2016-02-17" version="1">MSSFAIDVPETLLARARAGDGAAFEQIYRWFERPVFTLAVRIAGDRDEATEVLQETMLKVLTRIGDFRGHRDGSGTPFWGWLRQIAVNEALMRLRSRRRHEHADSEDEHLADDRAPPPPAAADAAALGRALAQLPEATRSVLWLYHAEGYTHEEIATLMQRSISFSKSQLARGGRRLRQLLEPEQAHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD63</accession>
    <name>A0A0S2DD63_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1133</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946546.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1133"/>
    <dbReference type="EnsemblBacteria" id="ALN56491">
        <property type="protein sequence ID" value="ALN56491"/>
        <property type="gene ID" value="GLE_1133"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1133"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1118"/>
    <dbReference type="OMA" id="VMARRAH"/>
    <dbReference type="OrthoDB" id="1196738at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="56"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="243" mass="26273" checksum="6D380FF6B1DDD383" modified="2016-02-17" version="1">MRCLVLPGLDGGGALLDDFLAAMRPRRDAHALAYPGDPALGYAELIDWVWPRLPAHEPFALIGESFSGPVAVALAARRPPQLKALVLCASFVRAPRPPWSPLGLAALPAWTHRLPLQRAPLAAAARAALGRWSTAQRRQRLRAALDALDPAVLRRRLGEIARVDARAALAGVAVPTLYLRATADRLVSRESWEDIRRARPRTECIALDAPHFVLQACPEEAAARIGDWLDRAGGPDADLADVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDJ7</accession>
    <name>A0A0S2DDJ7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DnaA regulatory inactivator Hda</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">hda</name>
        <name evidence="4" type="ORF">D9T17_21030</name>
        <name evidence="3" type="ORF">FE772_06630</name>
        <name evidence="2" type="ORF">GLE_1223</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">OH11</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000052">
        <property type="protein sequence ID" value="ROU04988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946611.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000052.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1223"/>
    <dbReference type="EnsemblBacteria" id="ALN56580">
        <property type="protein sequence ID" value="ALN56580"/>
        <property type="gene ID" value="GLE_1223"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1223"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1208"/>
    <dbReference type="OMA" id="DWGQIYR"/>
    <dbReference type="OrthoDB" id="1110566at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032297">
        <property type="term" value="P:negative regulation of DNA-templated DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013317">
        <property type="entry name" value="DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017788">
        <property type="entry name" value="Hda"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00308">
        <property type="entry name" value="Bac_DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03420">
        <property type="entry name" value="DnaA_homol_Hda"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_DnaA" evidence="1">
        <location>
            <begin position="52"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROU04988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="243" mass="26682" checksum="B78FC975EAB07D09" modified="2016-02-17" version="1">MSIPQLPLALRHSPDQRLETYVNAPDGAIAQLRSLASSDEETAGYRDPSGADWVYLAGPAGVGKTHLLLAACAQADIAGRRAAYVPLSAAVGRLREALQSLDTNNDLLALDGIEAIAGRREDEIALFDTHNRARQAGIAVIYASRENPDELKLTLPDLRSRLSQCTRIVLTPLDDDGRAQVLRQRAQRRGLALEEAALEWMLKRMDRDLGGLTQLLDKLDRASLAAQRRITVPFLKRTIDDET</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE54</accession>
    <name>A0A0S2DE54_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF418 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1463</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946795.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56820">
        <property type="protein sequence ID" value="ALN56820"/>
        <property type="gene ID" value="GLE_1463"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1463"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1444"/>
    <dbReference type="OMA" id="RTELYIW"/>
    <dbReference type="OrthoDB" id="1742337at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007349">
        <property type="entry name" value="DUF418"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04235">
        <property type="entry name" value="DUF418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="359"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="DUF418" evidence="2">
        <location>
            <begin position="238"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="414" mass="44100" checksum="10520C3F577F0798" modified="2016-02-17" version="1">MTASVPELAPVSVPERVTALDALRGLALLGILLSNVAAFAGPLNELHDGIDPTLRGSDRALATFVYVAIRDKAWTLFALLFGMGFAAMLGRAQAGGRGFGAVYLRRSAGLAAIGLIHAWAIWAGDILVTYALCAFALLALRRLSDEAWLALGCALYLAGTGFMLLVAASLTLPGVAQGGARELARAQAERAAEVAAYAHGDYAAAAAQRVHFFFDTTIAGWAVMLPLALGLFLIGAALMRSGTLADPARHRARLQAMLRYGGALGVGLTAASVALEPAPTVAVYTASSVLAQTLHIAGGLPLALAAIAAVTLLLEAGARWPLRFAAAGRMALTHYLTQSLVATWLLYGHGLGQWGRWSYSALILAALLLFAAQMAFSAWWLRRFRFGPVEWLWRAYTYRRWPPLRVERGHAQRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE71</accession>
    <name>A0A0S2DE71_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 15 16">Protoporphyrinogen IX oxidase</fullName>
            <shortName evidence="15">PPO</shortName>
            <ecNumber evidence="15 16">1.3.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">FE772_07570</name>
        <name evidence="17" type="ORF">GLE_1437</name>
    </gene>
    <organism evidence="17 19">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="17 19" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">C3</strain>
        </source>
    </reference>
    <reference evidence="18 20" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 20">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15 16">Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15 16">
            <text>3 A + protoporphyrinogen IX = 3 AH2 + protoporphyrin IX</text>
            <dbReference type="Rhea" id="RHEA:62000"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15 16">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="15 16">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 15 16">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrin-IX from protoporphyrinogen-IX: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 15">Cell membrane</location>
            <topology evidence="3 15">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 15 16">Belongs to the HemJ family.</text>
    </comment>
    <dbReference type="EC" id="1.3.99.-" evidence="15 16"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946773.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1437"/>
    <dbReference type="EnsemblBacteria" id="ALN56794">
        <property type="protein sequence ID" value="ALN56794"/>
        <property type="gene ID" value="GLE_1437"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1437"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1417"/>
    <dbReference type="OMA" id="VRLFIYH"/>
    <dbReference type="OrthoDB" id="1433260at2"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00324"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070818">
        <property type="term" value="F:protoporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02239">
        <property type="entry name" value="HemJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005265">
        <property type="entry name" value="HemJ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40255">
        <property type="entry name" value="PTHR40255"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03653">
        <property type="entry name" value="UPF0093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004638">
        <property type="entry name" value="UCP004638"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15 16" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 15 16" id="KW-0349">Heme</keyword>
    <keyword evidence="13 15 16" id="KW-0408">Iron</keyword>
    <keyword evidence="14 15 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 15 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR004638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ALN56794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="QCW25541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="150" mass="17063" checksum="C99DB4219F9978AD" modified="2016-02-17" version="1">MNAYLWTKTFHLVFVIAWMAAVFYLPRILVNIAESQGEPAVRARLALMGRKLYRFGHIMFGLAFLCGLLMWQGYRVFGDGLPQMFAVGGWLHAKLTLVVALLVYYSFTGRWIKGLDKGRALPSSRTLRLFNELPLLALIAIVWLVLAKPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEH0</accession>
    <name>A0A0S2DEH0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Outer membrane lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_1459</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C40 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1459"/>
    <dbReference type="EnsemblBacteria" id="ALN56816">
        <property type="protein sequence ID" value="ALN56816"/>
        <property type="gene ID" value="GLE_1459"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1459"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1440"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000064">
        <property type="entry name" value="NLP_P60_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00877">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51935">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="NlpC/P60" evidence="4">
        <location>
            <begin position="123"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="248" mass="26486" checksum="64FC7FB84E4255AF" modified="2016-02-17" version="1">MTTSTHRHNRQTATPQASCDTAQGRRPGRRASQRILLTAALAVCAVPAFAQSASAGMASSLLPGGPSLRNDSADAPQASGGHMLPEAMTLSDRALMLATDLNRMLGQGQDIPLSKTDLPVAEQGRIKGMLQKALALLGTPYRWGGTSPDQGFDCSGLVGYVFRNALGIELPRVSREMAKTGEVIDRDAMTEGDLVFFGRRGRVDHVGIYLGEGRFVHAPRTGKDVTVSSLDSGYWSGKFMEARRVDGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEI5</accession>
    <name>A0A0S2DEI5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_08070</name>
        <name evidence="2" type="ORF">GLE_1542</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56899">
        <property type="protein sequence ID" value="ALN56899"/>
        <property type="gene ID" value="GLE_1542"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1542"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1524"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242292" evidence="1">
        <location>
            <begin position="22"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="102" mass="11368" checksum="89652508AC363980" modified="2016-02-17" version="1">MRLRRFAFLLTLAFCSPPAAAHKISPGVYAEVPYNNNPFLFCTLGMPKDGWVAVNWRTGTWKPITQYPNLRWVPTYVRICPAAARPAGGGQPYRPSDRAATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DES6</accession>
    <name>A0A0S2DES6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF1877 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">D9T17_18650</name>
        <name evidence="2" type="ORF">FE772_08915</name>
        <name evidence="1" type="ORF">GLE_1724</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">OH11</strain>
        </source>
    </reference>
    <reference evidence="2 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000045">
        <property type="protein sequence ID" value="ROU05439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947008.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1724"/>
    <dbReference type="EnsemblBacteria" id="ALN57079">
        <property type="protein sequence ID" value="ALN57079"/>
        <property type="gene ID" value="GLE_1724"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1724"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1702"/>
    <dbReference type="OMA" id="MEMLCTL"/>
    <dbReference type="OrthoDB" id="1897239at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015068">
        <property type="entry name" value="DUF1877"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035944">
        <property type="entry name" value="YfbM-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08974">
        <property type="entry name" value="DUF1877"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111069">
        <property type="entry name" value="SSF111069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROU05439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="162" mass="17819" checksum="9CF975544E2A92CC" modified="2016-02-17" version="1">MGMTWSATAMDPARAAALLEQSRQIEEALYERDDQAAQDAYLDKAWHAIHFVLTGSAWTGEAPWAWAILGGTPVNEDDDASWRHLPAEQVREIAQALAALPPAEFAQRFDAQALADAQIYPDVIWLRDGEDAKQYVLDYYAQLSGFYAAAAARGDDVFATIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEV0</accession>
    <name>A0A0S2DEV0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Enolase</fullName>
            <ecNumber evidence="8">4.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">2-phospho-D-glycerate hydro-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">2-phosphoglycerate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 13" type="primary">eno</name>
        <name evidence="13" type="ORF">GLE_1488</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:10164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.2.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="8">The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell surface</location>
        </subcellularLocation>
        <text evidence="8">Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the enolase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1488"/>
    <dbReference type="EnsemblBacteria" id="ALN56845">
        <property type="protein sequence ID" value="ALN56845"/>
        <property type="gene ID" value="GLE_1488"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1488"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1469"/>
    <dbReference type="OMA" id="EFMIIPV"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00187"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000015">
        <property type="term" value="C:phosphopyruvate hydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03313">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020809">
        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="PTHR11902"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03952">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001400">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00002">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01193">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01060">
        <property type="entry name" value="eno"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 8 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Enolase_N" evidence="12">
        <location>
            <begin position="23"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="Enolase_C" evidence="11">
        <location>
            <begin position="158"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="383"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8 9">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="356"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="304"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="331"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent; in inhibited form" evidence="8">
        <location>
            <position position="356"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="407"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_00318"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR001400-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN56845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="447" mass="47821" checksum="E5F20A1EA159FC12" modified="2016-02-17" version="1">MAWPAPRLFPLPTLADPSDMTSITQIHAREILDSRGNPTLEAEVTLADGSFGRAMVPSGASTGSKEAVELRDGDKTRYLGKGVRKAVENVNTTIAQALKGLDATDQAALDKRMIDLDGTENKGRLGANALLGVSLANAHAVAASKKLPLWKYLAGDRAPVLPVPMMNIINGGAHADNNVDLQEFMILPVGVANFAEALRAGAEVFHALKSVLKGRGLSTAVGDEGGFAPDLRSNEEALETILEAIGKAGYKAGEDILLGLDVASTEFYDNGKYHLVGEGKRLTSEQFVDFLANWAAQYPIVTIEDGMSEDDWNGWKLLTDKIGNKVQLVGDDLFVTNPKIFAEGIDKGVANAILIKVNQIGTLTETLEAIAMADRAKYAAVVSHRSGETEDTTIADISVATTATQIKTGSLCRSDRVAKYNQLLRIEEQLGSAARYAGRDAFVSLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFC8</accession>
    <name>A0A0S2DFC8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1933</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57284">
        <property type="protein sequence ID" value="ALN57284"/>
        <property type="gene ID" value="GLE_1933"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1933"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="208" mass="22170" checksum="4A1CA47B926F9C8E" modified="2016-02-17" version="1">MARARPACAGSGLSHMPGANARLCSDGRRATCRLPRAIKSNALFPACVPPDPPMCGTPKPAPDGGFARTCEARVTVKFPDRSYGLRRAADPETLAVRNTHPTTTKYGASPNYRARRSRLWAAYTALRFLGYNTRARAAEVAGGKSGGSKPRTAGGRIPLAGVVLAALPTQKTRRLRPKTPGAKNPPIDGGGCRCSWSFEAPSERIWQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFT7</accession>
    <name>A0A0S2DFT7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1862</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57214">
        <property type="protein sequence ID" value="ALN57214"/>
        <property type="gene ID" value="GLE_1862"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1862"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1833"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="85" mass="9573" checksum="84031E2CF69B244B" modified="2016-02-17" version="1">MAVASIFLQLSVADKLLALRDDRRKIQQHIGDAIQCFLIVNRCDFYMPTIRRDPHARRISSMQGVLSSLCSGGYRGYLTGRKTDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFV4</accession>
    <name>A0A0S2DFV4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amino-acid acetyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.1</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="3">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">argA</name>
        <name evidence="3" type="ORF">FE772_09430</name>
        <name evidence="2" type="ORF">GLE_1840</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.3.1.1" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947086.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1840"/>
    <dbReference type="EnsemblBacteria" id="ALN57192">
        <property type="protein sequence ID" value="ALN57192"/>
        <property type="gene ID" value="GLE_1840"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1840"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1811"/>
    <dbReference type="OMA" id="ELWKLWY"/>
    <dbReference type="OrthoDB" id="1374795at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004042">
        <property type="term" value="F:acetyl-CoA:L-glutamate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103045">
        <property type="term" value="F:methione N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="18"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="206" mass="22303" checksum="3B34773D1E90DBAF" modified="2016-02-17" version="1">MAGNEAWSLQPRLSGEHVTLEPLDCAHADGLRAALAGGELAKAWYTNVPAPEGVDGYIEAALAMQQRGAAWAFAVLDARGEVVGSTRYYDMDAAVPRVQIGYTFYAPRVQRTGLNTQAKLLLLGHAFETLGCIAVGFETSWFNLASRTAIARLGAKQDGVLRNHRRHADGSPRDTVAFSIIDTEWPAVKRSLQYKLDQHSNGAAHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG01</accession>
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                <person name="Fernandez C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Feng T."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGF4</accession>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <source>
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</entry>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57749">
        <property type="protein sequence ID" value="ALN57749"/>
        <property type="gene ID" value="GLE_2400"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2400"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2362"/>
    <dbReference type="OMA" id="YHEASCA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595544" evidence="2">
        <location>
            <begin position="23"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="247" mass="25396" checksum="8D04E11829635E4B" modified="2016-02-17" version="1">MKTLAFASLTMFPILAAAQAGAAPSTAPLQRDVRWIDAQDRSRVATQVLTRRADGALVYRYDRQATPARRYHERMCELVGGVPAAGDTVLGGADAAGSLACTLPADAAGTPGVVVDGLFHPSPRPPANAAAQGQDAARADASDDFAHAAAPGGAAPRGENFQAVGGAGYSSETGGTGSAKTSLDNDRCTIEQTTPVPAGASESVLLLVTCIEQRVRALPTYTRACMNATCVTENGFIDVLDLSPPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGQ5</accession>
    <name>A0A0S2DGQ5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2406</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947517.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57755">
        <property type="protein sequence ID" value="ALN57755"/>
        <property type="gene ID" value="GLE_2406"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2406"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2368"/>
    <dbReference type="OMA" id="TAMIQHE"/>
    <dbReference type="OrthoDB" id="1087129at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="31"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="404" mass="44845" checksum="84D83CAC597F3F15" modified="2016-02-17" version="1">MDLKSGYPFWAIRNGLMHAFPRLREDLDCEVAVIGGGISGALIADELAAHGHDVAVLEQRDIAWGSTAASTALLQYEIDTHLAELSQRYGEPRAALAYRACAAAVERLGEVAADLRGVDFRRQRSLYYASRAGHVPLLREEAALRARHGLTLRWLDADELAADYGLRAPGAILSDCAAAVDPYRMTSRLLARLRRRGAGVYDRTRIQALHATSRKVELRTGEGLRVRADRVVVAAGYAGQHWIDQRLARNRSSYAFVTDPLDADDLQALGETLVWESARPYLYLRSTGDGRLVVGGCDNAIDLPARRDRRVQSRAQRLVRQVQQRFPRLRLQPAFAWAGTFAETADGLPWFGPHPQHGPRVLFAMAYGGNGITYSMIGAELLRARIERRAHPLARLFSFERTVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGQ7</accession>
    <name>A0A0S2DGQ7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">30S ribosomal protein S15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 8" type="primary">rpsO</name>
        <name evidence="9" type="ORF">BV903_08705</name>
        <name evidence="11" type="ORF">D9T17_13365</name>
        <name evidence="10" type="ORF">FE772_10995</name>
        <name evidence="8" type="ORF">GLE_2179</name>
    </gene>
    <organism evidence="8 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 12">C3</strain>
        </source>
    </reference>
    <reference evidence="9 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">OH11</strain>
        </source>
    </reference>
    <reference evidence="10 15" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="3 6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000018">
        <property type="protein sequence ID" value="OPD64371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000033">
        <property type="protein sequence ID" value="ROU06438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947342.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2179"/>
    <dbReference type="EnsemblBacteria" id="ALN57528">
        <property type="protein sequence ID" value="ALN57528"/>
        <property type="gene ID" value="GLE_2179"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64371">
        <property type="protein sequence ID" value="OPD64371"/>
        <property type="gene ID" value="BV903_08705"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2179"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2141"/>
    <dbReference type="OMA" id="FKTHVKD"/>
    <dbReference type="OrthoDB" id="1990141at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_B">
        <property type="entry name" value="Ribosomal_S15_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_S15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005290">
        <property type="entry name" value="Ribosomal_S15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="S15_NS1_RNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23321">
        <property type="entry name" value="PTHR23321"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="SSF47060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00952">
        <property type="entry name" value="S15_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00362">
        <property type="entry name" value="RIBOSOMAL_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN57528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD64371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW26119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROU06438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="86" mass="10067" checksum="857D4D8C3BC9B502" modified="2016-02-17" version="1">MSIDTQKVIEDNKRGANDTGSPEVQVALLTARIEQLTGHFKAHKQDHHSRRGLLMMVNRRRSLLDYLKRKDNERYKALIEKLGLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGR7</accession>
    <name>A0A0S2DGR7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FE772_11875</name>
        <name evidence="6" type="ORF">GLE_2372</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947489.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2372"/>
    <dbReference type="EnsemblBacteria" id="ALN57721">
        <property type="protein sequence ID" value="ALN57721"/>
        <property type="gene ID" value="GLE_2372"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2372"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2333"/>
    <dbReference type="OMA" id="LIQLRWI"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="217"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW26264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="433" mass="46832" checksum="73043957B2EF0064" modified="2016-02-17" version="1">MQLAPPLPASRDGTGVKNMHQLIQLRWIAVIGQVATIVFVHYGFGIKLPLMPMAIVLACLAAFNLVSMLRWRKREEVTNGALFLALLVDILTLTAQLYLSGGAANPFVFLYLLQVALACVLLRTWASCAVVVVTTACFIALTAFAGPVVIPADPTRGLRDPYVQGLLLCFALNATLLVVFITRIGRNLRARDQRLADLRQRAAEEEHIVRMGLLASGAAHELGTPLATLSVILGDWRRMPPFTQQPELLQELDEMQTQLTRCKSIVTGILLSAGEARGEAPAITTVAEFLDDLVGEWRTTRPVRGFDYENGFGEDVAIISDSGLKQMICNVLDNALEASPGWVGLESWRDEDRLVLRVSDAGPGFAPAMLSHFGKPYQSSKGRPGGGLGLFLALNVARQLGGSMVARNREPSGAVVTMSLPLAALTPPEPSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGS2</accession>
    <name>A0A0S2DGS2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA ligase (ATP)</fullName>
            <ecNumber evidence="1">6.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">lig</name>
        <name evidence="7" type="ORF">GLE_2471</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.5.1.1" evidence="1"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947561.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2471"/>
    <dbReference type="EnsemblBacteria" id="ALN57820">
        <property type="protein sequence ID" value="ALN57820"/>
        <property type="gene ID" value="GLE_2471"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2471"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2433"/>
    <dbReference type="OMA" id="WLFEESY"/>
    <dbReference type="OrthoDB" id="1073940at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026333">
        <property type="entry name" value="ATP_dep_DNA_lig_pp_1105_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012309">
        <property type="entry name" value="DNA_ligase_ATP-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012308">
        <property type="entry name" value="DNA_ligase_ATP-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036599">
        <property type="entry name" value="DNA_ligase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04679">
        <property type="entry name" value="DNA_ligase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04675">
        <property type="entry name" value="DNA_ligase_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04120">
        <property type="entry name" value="DNA_lig_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_LIGASE_A3" evidence="6">
        <location>
            <begin position="307"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="532" mass="59694" checksum="AF62AE4C234BB2DF" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH12</accession>
    <name>A0A0S2DH12_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">VWA domain containing CoxE-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2291</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947427.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2291"/>
    <dbReference type="EnsemblBacteria" id="ALN57640">
        <property type="protein sequence ID" value="ALN57640"/>
        <property type="gene ID" value="GLE_2291"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2291"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2256"/>
    <dbReference type="OMA" id="DIDWNRT"/>
    <dbReference type="OrthoDB" id="434825at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008912">
        <property type="entry name" value="Uncharacterised_CoxE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05762">
        <property type="entry name" value="VWA_CoxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="404" mass="43626" checksum="C7087FB449C381C2" modified="2016-02-17" version="1">MSAASDSADTDLPADAATPSTREERWRMVLGSEAQDSCGGLGAGLSPMDAALAALYEPSGPGGLSRRGGRGGSAPNVARWLGDIRKYFPTSVVQVMQRDALQRLDLRQMLLEKEMLEGIQPDVHMVANLVSLSGVIPAETKQTARMVVRRVVEELMRKLEEPMRSAVTGALDRARRTRRPRHAEIDWNRTIRANLKHWQPEYNTVIPQQLIGFGRKSRRPQREITLCIDQSGSMAASVVYSSIFGAVMASLPAVSTRLVVFDTAVVDMTEQLDDPVDLLFGVQLGGGTDIHGAVAYCQGLIREPRNSILVLISDLYEGGVEAKLLARAQELVEAGVQFIVLLALSDEGRPAYDQALAAKLAALGVPSFACTPDAFPGLMAAAIRRDDVNQWAAGNGLVPTRAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH76</accession>
    <name>A0A0S2DH76_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Flavin reductase family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Flavin reductase like domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_12050</name>
        <name evidence="2" type="ORF">GLE_2408</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947519.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2408"/>
    <dbReference type="EnsemblBacteria" id="ALN57757">
        <property type="protein sequence ID" value="ALN57757"/>
        <property type="gene ID" value="GLE_2408"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2408"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2370"/>
    <dbReference type="OMA" id="WAMPLDF"/>
    <dbReference type="OrthoDB" id="1681849at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016646">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin_Reduct" evidence="1">
        <location>
            <begin position="15"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="196" mass="21068" checksum="7E562F7318D0A304" modified="2016-02-17" version="1">MSPILAPVALAKASRLINHGPTVLVSARHDGVDNVMAAAWACALDYDPPKLTVVIDKATRTRALIERSGAFAVQVPTAAQAAMTHRVGTHSRSDEPDKLARAGVGLFAIDGHDLPFVAGCSAWMACRLIREPHNQEIYDLFIGEIVGAWSDPRAFADGHWRFEHADPALRSLHYIAGGHFYAIGEAIDVAAQDAPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH81</accession>
    <name>A0A0S2DH81_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Condensation domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2621</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2621"/>
    <dbReference type="EnsemblBacteria" id="ALN57969">
        <property type="protein sequence ID" value="ALN57969"/>
        <property type="gene ID" value="GLE_2621"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2621"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2580"/>
    <dbReference type="OMA" id="MARIDFT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensation" evidence="1">
        <location>
            <begin position="1"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="422" mass="46947" checksum="EC81584EDBE68451" modified="2016-02-17" version="1">MWSAQQLDPDSPALWTAEAVELEGPLDEAALEAAIRETLQACDALHMRYEGEGADVVQRLRESRSVVIGREDYAGCDQPWDSAWRWMREDLLRPADLARRPLFATALIRLGAQRHLWYLRAHHIALDGFAYLLLIHRVAELYSARTGGRAAAAARDWSLAPLVAEEARYRASPESARSREFWLQRCADRAEPVTLGPKCAPDDSARSSRLQLPAGEHQRWHHAARAIGVDWSAWLIAAVFAWMRARSGSDAISLGLLVMNRLGSAALGVPCMGMNVVPLRLRLQPQWSFAELARAVAAELRELRPHQRYNYEWLRQDLGLGDSHAQLYGPVLNLMPFDRGFVFDGLRSRAHPVSVGSVEDLDLTVSPLADGVRFDIEANPQAYDAATLDAHHRALVATMRAALADSSLRLDQLHSALAREAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHD2</accession>
    <name>A0A0S2DHD2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl transferase, WecB/TagA/CpsF family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2462</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2462"/>
    <dbReference type="EnsemblBacteria" id="ALN57811">
        <property type="protein sequence ID" value="ALN57811"/>
        <property type="gene ID" value="GLE_2462"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2462"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2424"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06533">
        <property type="entry name" value="Glyco_transf_WecG_TagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004629">
        <property type="entry name" value="WecG_TagA_CpsF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34136">
        <property type="entry name" value="PTHR34136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03808">
        <property type="entry name" value="Glyco_tran_WecG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00696">
        <property type="entry name" value="wecG_tagA_cpsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="465" mass="50190" checksum="06667F83D738311E" modified="2016-02-17" version="1">MNAAAPSPDAAPRRLLELLDRLLIVRDAAQYRALLQRLADPAGATVLSFFNQHAFNLAWTDPAFAEHLRRSDVLLRDGVGVAACLRLLAREPGLNANGTDLIPRLLAAFAGRRAVLIGTREPYLQRAAQRLGEDYAVEVACALDGFGDAAGYLEAVARERPDLVVLAMGMPKQERVAAELAQWARQAGHRLLIVNGGAIADFIAGRVARAPAWMRRARLEWLYRLGREPRRLWRRYLLGGAVFIARALRLAAQPPRPASGIAPLSEASTMKADTPALFGLDEARIAQLVQRLDASAGASERRIVQFAAARAGEGATALAHSYAAASAQLRKRRVLLLSDDAQGDVACFADCFAQAAAAGAPGLTLARLTDPRREFRDNYAALDDADAWQALAQRFDEVVVDARAPYALAAAKHASGVVVVVEAEATRAALVRTLLDDLAAVDARVIGTVLNKHRSHLPHALHERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHG4</accession>
    <name>A0A0S2DHG4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD dependent oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">FAD-binding oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_13250</name>
        <name evidence="2" type="ORF">GLE_2641</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947699.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2641"/>
    <dbReference type="EnsemblBacteria" id="ALN57989">
        <property type="protein sequence ID" value="ALN57989"/>
        <property type="gene ID" value="GLE_2641"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2641"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2600"/>
    <dbReference type="OMA" id="AMNGCFG"/>
    <dbReference type="OrthoDB" id="912110at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="8"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="486" mass="52404" checksum="E34F823691EB5706" modified="2016-02-17" version="1">MADYDGYDVVVVGNGVLGMATAHALQLRDPGLRVAVVGPAPRPGAASAAAGAMMGCYGEVTAQLLRTPSGRAKLAKGLLAARHWPDWLESINQALPAEERIALTPGTIVFSNNKSGIIEDENYAAIVQALEENGAAYETLDPNRIDGLAPAEDCRPSRALYLPDEGSIDAAKLLGALSALIERSPTLSFIDDTATGLDIHGGRIRAVRLREGGRVAAAQVVLAAGVWTQAVLDSVPELARRIPRLFCGGGTSLLLDTGPRAQAHVLRTPNRAFACGLHAVPRGGGRLYVGATNTLFAQPMLRTSPADMFFLLECALDQLDQDLCAAQLVAWQAGNRPVAVDTCPLIGPTSVEGLWLLTGTYRDGLFLSPLLGRHIADRVCGGPGLFEETFAPERKPIRLYTVEQARAEALKHYLAMGSEHGIRLPRVGWHHAFPRFYEQMLNGLYDELGEDEFVLAPELLAIVAADRKRMVPFFRDYYAQVRQAWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHN4</accession>
    <name>A0A0S2DHN4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Citrate transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">GntP family permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_06470</name>
        <name evidence="4" type="ORF">FE772_14310</name>
        <name evidence="2" type="ORF">GLE_2866</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000011">
        <property type="protein sequence ID" value="OPD64840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947871.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000011.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2866"/>
    <dbReference type="EnsemblBacteria" id="ALN58214">
        <property type="protein sequence ID" value="ALN58214"/>
        <property type="gene ID" value="GLE_2866"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64840">
        <property type="protein sequence ID" value="OPD64840"/>
        <property type="gene ID" value="BV903_06470"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2866"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2828"/>
    <dbReference type="OMA" id="TAIWAVQ"/>
    <dbReference type="OrthoDB" id="1585405at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015128">
        <property type="term" value="F:gluconate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003474">
        <property type="entry name" value="Glcn_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30354">
        <property type="entry name" value="PTHR30354"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="362"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="441"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="465" mass="48437" checksum="4F0AC58F95190D07" modified="2016-02-17" version="1">MAFLIVLAALCFLMYVAYRGHSVILFAPVAALGAVLLTDPALVAPMFTGLFMDKMVGFLKLYFPVFLLGAIFGKVIETSGFSKSIVAATIRLVGRERAMLAIVAVCALLTYGGVSLFVVVFAVYPFAAELFRQSDIPKRLIPGTIALGAFTFTMDALPGTPQIQNIIPTAFFGTDTWAAPWLGTLGGVFILIVGLIYLNWRRRSALKAGEGYGTQLVNEPAPFAGGTLAHPLVAIAPLLVVGVANKLFSEWLPRFYGKQHSFVPAVIGDAAPVVQEVSKVAAIWAVEGALLLGIATVLAFAWKPVTKSFAEGSKAAIGGALLAAMNTASEYGFGAVIAALPGFLVVANALGAIPNPLVNEAVTVTALAGITGSASGGMSIALAAMSETFIANAQAANIPMEVLHRVASMASGGMDTLPHNGAVITLLAVTGLTHRQAYKDVFAITLIKTAAVFVVIATFYATGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHP5</accession>
    <name>A0A0S2DHP5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">EvpB family type VI secretion protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Type VI secretion protein, EvpB/VC_A0108 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Type VI secretion system contractile sheath large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">tssC</name>
        <name evidence="4" type="ORF">BV903_00060</name>
        <name evidence="5" type="ORF">FE772_12910</name>
        <name evidence="3" type="ORF">GLE_2573</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000001">
        <property type="protein sequence ID" value="OPD65945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947646.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2573"/>
    <dbReference type="EnsemblBacteria" id="ALN57922">
        <property type="protein sequence ID" value="ALN57922"/>
        <property type="gene ID" value="GLE_2573"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65945">
        <property type="protein sequence ID" value="OPD65945"/>
        <property type="gene ID" value="BV903_00060"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2573"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2532"/>
    <dbReference type="OMA" id="EYGWCTS"/>
    <dbReference type="OrthoDB" id="683477at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010269">
        <property type="entry name" value="T6SS_TssC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044032">
        <property type="entry name" value="TssC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044031">
        <property type="entry name" value="TssC1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35565">
        <property type="entry name" value="PTHR35565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05943">
        <property type="entry name" value="VipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18945">
        <property type="entry name" value="VipB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03355">
        <property type="entry name" value="VI_chp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VipB" evidence="1">
        <location>
            <begin position="75"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="VipB_2" evidence="2">
        <location>
            <begin position="387"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD65945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="504" mass="55910" checksum="76DC5E71D30DF69E" modified="2016-02-17" version="1">MATTQKAVATAEALETAPSVDAPSINDFSALLAREFRPRNERAGEEVRSAVRTLAEQVLERSDIISADVTQTLSAYIAEIDRKLSEQLNLVMHNAQFQKMEGAWRGLHYLVTNTETDTLLKIRVLNVSKAELGKNLKRFKGVAWDQSPVFKKVYEEEYGQLGGEPYGCLIGDYYFDHSPQDVEMLRGIGQIAAAAHAPFIGAASPSLMGMESWGELSNPRDLAKIFTTPDYAAWRSLRGSDDAKYLALAMPRTLSRLPYGARTEPVEEFDFEEDTEGADSSRYTWQNAAYAMAVNVNRSFKLYGWCTRIRGVESGGAVEGLPAHTFPTDDGGVDMKCPTEIAITDRRSAELDKMGLMPLVHRKNSDMAAFIGAQSLGRPEEYDDPDATANAALSARLPYMFACSRFAHYLKCIARDKIGSFSTREQVQSWLTDWVMNYVDGDPANSSEEAKARKPLAAAEVQVEEVEGNPGYYTSKFFLRPHYQLEGLTVSLRLVSRLPSAQAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIC7</accession>
    <name>A0A0S2DIC7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Aminomethyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Folate-binding protein YgfZ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_15235</name>
        <name evidence="1" type="ORF">GLE_3048</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948004.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3048"/>
    <dbReference type="EnsemblBacteria" id="ALN58395">
        <property type="protein sequence ID" value="ALN58395"/>
        <property type="gene ID" value="GLE_3048"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3048"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3008"/>
    <dbReference type="OMA" id="VNFKKGC"/>
    <dbReference type="OrthoDB" id="1984573at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045179">
        <property type="entry name" value="YgfZ/GcvT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017703">
        <property type="entry name" value="YgfZ/GcvT_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22602">
        <property type="entry name" value="PTHR22602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03317">
        <property type="entry name" value="ygfZ_signature"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="287" mass="30595" checksum="AD822F8137D30C8F" modified="2016-02-17" version="1">MPDNPHALPGQAFALPGQRLIALEGRDAAAFAQAQFMNDVKGLADGHWQWSGWLTPKGRAVALFALLRLSEQRIWLVVPDADADALVEALKRFVFRSKVAIGAREDQVIEGRFGAPERAAGAVIDGDGDDSVEIDLSGDGGARTLRIVATGRAAAADADLAERWAEADLRHGLPRLPASQAGQWTPQQLSLDRLRGYSVKKGCYPGQEIVARTHFLGKAKRGLALYRCEGPVETGAKLMAGEETLGEIVARAGEWALAVAGLDREPTPAQAGATLLQPQPLSAGLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIE4</accession>
    <name>A0A0S2DIE4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Efflux RND transporter periplasmic adaptor subunit</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_14655</name>
        <name evidence="4" type="ORF">GLE_2938</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947927.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2938"/>
    <dbReference type="EnsemblBacteria" id="ALN58286">
        <property type="protein sequence ID" value="ALN58286"/>
        <property type="gene ID" value="GLE_2938"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2938"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2900"/>
    <dbReference type="OMA" id="RGCIDNR"/>
    <dbReference type="OrthoDB" id="1432684at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242152" evidence="2">
        <location>
            <begin position="41"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="73"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="382" mass="39836" checksum="98FD105CA7B84C6B" modified="2016-02-17" version="1">MRQLTNNREGGPAVRVTAAVAALALACALGLSACKGGAGAADAQAKEGKDKVSDAVPVEIAAATRRAIAASYTGTAPLEARAESQVVAKTSGVALDVMVVEGQQVKAGQVLVRLDSARAEQQAAQTGATLRKLEANYARSRQLAEQRLLSANDNDQLRYDMENARAANRLANLELSYAKVEAPISGVVASRSIKAGNFVQINSPIIRIVDTSMLEATLNVPERELATLKAGQPVQMTVDAMPGKSFEGKVDRIAPVVDSGSGTFRVICSFVGGGVLQPGMFGRLRIDYDSRADALVVPRAALLDDEGDPAVFVVRGNKVARTSVKLGYLDGSWAEVRQGVKLGDQVVVAGKTALREGSEVLPINAKPVASAAAPAAKAPVKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIG3</accession>
    <name>A0A0S2DIG3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fe/S biogenesis protein NfuA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nfuA</name>
        <name evidence="10" type="ORF">BV903_02835</name>
        <name evidence="11" type="ORF">FE772_14680</name>
        <name evidence="9" type="ORF">GLE_2944</name>
    </gene>
    <organism evidence="9 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">C3</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5">Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the NfuA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000005">
        <property type="protein sequence ID" value="OPD65470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947929.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000005.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2944"/>
    <dbReference type="EnsemblBacteria" id="ALN58292">
        <property type="protein sequence ID" value="ALN58292"/>
        <property type="gene ID" value="GLE_2944"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65470">
        <property type="protein sequence ID" value="OPD65470"/>
        <property type="gene ID" value="BV903_02835"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2944"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2906"/>
    <dbReference type="OMA" id="CLAYCRP"/>
    <dbReference type="OrthoDB" id="2010888at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01637">
        <property type="entry name" value="Fe_S_biogen_NfuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017726">
        <property type="entry name" value="Fe/S_biogenesis_protein_NfuA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="FeS_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001075">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01106">
        <property type="entry name" value="NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="SSF89360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-S_biosyn" evidence="8">
        <location>
            <begin position="2"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="NifU" evidence="7">
        <location>
            <begin position="115"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN58292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD65470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW26713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="198" mass="21349" checksum="4D721593335E5D74" modified="2016-02-17" version="1">MINISESAQAHFRKLIEREALPGLGVRLSAVHPGTARADVRLEFAEPADLDGDEWAIDCEGFTLWLRADSVKYLDGAEIDYETRATGGQLQIRAPKIKGEAPADSASLVERVHWLVENEINPQLAQHRGHVSVQEVTADGVVLLRFGGGCHGCGMADVTLKQGIETTLMSKVPGVTAVRDATDHDTGQAPYIPRDSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIH5</accession>
    <name>A0A0S2DIH5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58421">
        <property type="protein sequence ID" value="ALN58421"/>
        <property type="gene ID" value="GLE_3074"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3074"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3034"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="41" mass="4618" checksum="CBEB9AB14D4E1B2D" modified="2016-02-17" version="1">MSRAVVFKPLRELQTQTQVELSRPPRRAMVATMPSPPRSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIJ7</accession>
    <name>A0A0S2DIJ7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3123</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58470">
        <property type="protein sequence ID" value="ALN58470"/>
        <property type="gene ID" value="GLE_3123"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3123"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="49" mass="5217" checksum="BC31237654C6D18F" modified="2016-02-17" version="1">MHGRRKSVGDAGEMGADGGESKRRMGFAAPPQPSFPRTRESRDFGALPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIK7</accession>
    <name>A0A0S2DIK7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Aspartate 1-decarboxylase</fullName>
            <ecNumber evidence="9">4.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Aspartate alpha-decarboxylase</fullName>
        </alternativeName>
        <component>
            <recommendedName>
                <fullName evidence="9">Aspartate 1-decarboxylase beta chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="9">Aspartate 1-decarboxylase alpha chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="9 14" type="primary">panD</name>
        <name evidence="15" type="ORF">BV903_09405</name>
        <name evidence="16" type="ORF">FE772_15770</name>
        <name evidence="14" type="ORF">GLE_3173</name>
    </gene>
    <organism evidence="14 17">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">C3</strain>
        </source>
    </reference>
    <reference evidence="15 18" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 18">B25</strain>
        </source>
    </reference>
    <reference evidence="16 19" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 19">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>H(+) + L-aspartate = beta-alanine + CO2</text>
            <dbReference type="Rhea" id="RHEA:19497"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:57966"/>
            <dbReference type="EC" id="4.1.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9 10">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
        <text evidence="9 10">Binds 1 pyruvoyl group covalently per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Cofactor biosynthesis; (R)-pantothenate biosynthesis; beta-alanine from L-aspartate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Heterooctamer of four alpha and four beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="9 12">Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the PanD family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.11" evidence="9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000020">
        <property type="protein sequence ID" value="OPD64249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948096.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000020.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3173"/>
    <dbReference type="EnsemblBacteria" id="ALN58519">
        <property type="protein sequence ID" value="ALN58519"/>
        <property type="gene ID" value="GLE_3173"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64249">
        <property type="protein sequence ID" value="OPD64249"/>
        <property type="gene ID" value="BV903_09405"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3173"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3128"/>
    <dbReference type="OMA" id="MLYSKIH"/>
    <dbReference type="OrthoDB" id="1751990at2"/>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00002"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004068">
        <property type="term" value="F:aspartate 1-decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006523">
        <property type="term" value="P:alanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06919">
        <property type="entry name" value="Asp_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00446">
        <property type="entry name" value="PanD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003190">
        <property type="entry name" value="Asp_decarbox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21012">
        <property type="entry name" value="PTHR21012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02261">
        <property type="entry name" value="Asp_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006246">
        <property type="entry name" value="Asp_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00223">
        <property type="entry name" value="panD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="1 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6 9 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 9" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="8 9 10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 10" id="KW-0704">Schiff base</keyword>
    <keyword evidence="5 9" id="KW-0865">Zymogen</keyword>
    <feature type="chain" id="PRO_5011333651" description="Aspartate 1-decarboxylase beta chain" evidence="9 13">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011333652" description="Aspartate 1-decarboxylase alpha chain" evidence="9 13">
        <location>
            <begin position="25"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9 11">
        <location>
            <begin position="73"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via pyruvic acid" evidence="9 10">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9 10">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9 11">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="Pyruvic acid (Ser)" evidence="9 12">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006246-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR006246-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR006246-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR006246-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN58519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OPD64249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QCW26882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="126" mass="13779" checksum="509FA651686895DB" modified="2016-02-17" version="1">MQLNLLKAKIHRATVTHAELHYEGSCAIDGRLLDISGIREYEMVHIYNINSGHRFSTYAIRGEEGSGVISVNGAAAHKAQPGDLVIICAYGICDEAEAAKYKPTLVYVDRDNQLTHTNHSMPAQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIL0</accession>
    <name>A0A0S2DIL0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Poly(Hydroxyalcanoate) granule associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_03050</name>
        <name evidence="4" type="ORF">FE772_14965</name>
        <name evidence="2" type="ORF">GLE_2992</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000005">
        <property type="protein sequence ID" value="OPD65509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947965.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000005.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2992"/>
    <dbReference type="EnsemblBacteria" id="ALN58340">
        <property type="protein sequence ID" value="ALN58340"/>
        <property type="gene ID" value="GLE_2992"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65509">
        <property type="protein sequence ID" value="OPD65509"/>
        <property type="gene ID" value="BV903_03050"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2992"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2953"/>
    <dbReference type="OMA" id="QQIWQAG"/>
    <dbReference type="OrthoDB" id="1542147at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008769">
        <property type="entry name" value="PhaF_PhaI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38664">
        <property type="entry name" value="PTHR38664"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05597">
        <property type="entry name" value="Phasin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01837">
        <property type="entry name" value="PHA_granule_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD65509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="196" mass="20565" checksum="C75904D3DE1ED849" modified="2016-02-17" version="1">MAAKFKKTAKKTSGKTRSAGAAGKGAGAQEQAERLSKSLSESAQQIWLAGVGAFGRAQAEGTKLFEGLVKEGLTLEQATRKFTGGQAGALRDAVESKVGQARERAADTWDRLEKVFEERVQRALVKLGVPGREDLAELSERVDALTAELRRQGGAAPARKSAARAAKPKAAKAADKPAKAKAPRKAVAKPKPPVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ63</accession>
    <name>A0A0S2DJ63_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="12">TonB family C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLE_2980</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TonB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947955.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2980"/>
    <dbReference type="EnsemblBacteria" id="ALN58328">
        <property type="protein sequence ID" value="ALN58328"/>
        <property type="gene ID" value="GLE_2980"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2980"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2941"/>
    <dbReference type="OrthoDB" id="2074833at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_C" evidence="11">
        <location>
            <begin position="116"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN58328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="196" mass="20734" checksum="D018AA3B6B994919" modified="2016-02-17" version="1">MSTASHSIDSDAREHEAPAIATGESPGRTGLWLLLILLGAAFLGWYFYGKRPVQQAPAPLAPVLALPPVERTPGTAADLDKAQAAAAKAVAKGAREKSAVAAKPRATDARALARNPQPQYPAAALRRGEGGTVVLRVNVGADGKADQVALARRSGSRDLDRAAMVAVRDWRFKPATRNGREVASVVEQPVEFRPMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ69</accession>
    <name>A0A0S2DJ69_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FE772_16020</name>
        <name evidence="6" type="ORF">GLE_3226</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <sequence length="250" mass="25935" checksum="B8B168EF739A2EB0" modified="2016-02-17" version="1">MNDMGGMDLNGRSRRAALLHLGLAASALALTPGAAPAAGGANDAGDDLMRVGMVVFDGFQLLDVFGPLEMFGALRDRLRIAILAQNTGLVASSAGPAVAVDRAFADAPDLDVLLVPGGMGTRREVGNAALIEAVKALALKTPHVASICTGAAILARTGVLDGARATTNKRAFAWATAQGPKVDWVERARWVEDGKYFTSSGISAGMDMSLALIAKLFGGDTATRVANGAEYRWNRDPDEDPFAALNGLAR</sequence>
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<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
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    </evidence>
    <sequence length="134" mass="14002" checksum="8C50B1C8BC236B33" modified="2016-02-17" version="1">MKPKISALIALALTLAANATVAAPPRAVPVVVGGNEVLDACGSQGRVHGLKAGGDGFLAVRDGPGAAYAMTDKLGENLWVMMCDQRGDWIAVVYSEDGRLGRCGVGSPIAERQPYRGPCKSGWVHGRWIELMAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
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                <person name="Fernandez C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="22"/>
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        </location>
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    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="209" mass="22113" checksum="D72DA4500213D9A0" modified="2016-02-17" version="1">MSKLLPFGLLLALCLTPAATGAQHRGFDLSQLDLSQLDLSRLDPAAIMASANDTLMRAPDARIDGLFQALRSASRDRGDAATLCALFDPHADRSAQALMAAAQRLSPDSHQRFGNALIEIAASGLQSPRQAYDAGAAKQSLKSAAAQAMMLHDGFGAGLNADGADETSRQARCQSFAWLLDALGEQPLAQRAGAMRLLLNEGMNRLAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK29</accession>
    <name>A0A0S2DK29_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MerR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MerR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_16720</name>
        <name evidence="5" type="ORF">D9T17_10325</name>
        <name evidence="4" type="ORF">FE772_17545</name>
        <name evidence="2" type="ORF">GLE_3562</name>
    </gene>
    <organism evidence="2 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">C3</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 9" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000045">
        <property type="protein sequence ID" value="OPD62744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000023">
        <property type="protein sequence ID" value="ROU07340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948383.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3562"/>
    <dbReference type="EnsemblBacteria" id="ALN58906">
        <property type="protein sequence ID" value="ALN58906"/>
        <property type="gene ID" value="GLE_3562"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62744">
        <property type="protein sequence ID" value="OPD62744"/>
        <property type="gene ID" value="BV903_16720"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3562"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3506"/>
    <dbReference type="OMA" id="AKGNRMF"/>
    <dbReference type="OrthoDB" id="1661714at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="18"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU07340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="118" mass="13854" checksum="2817168A342FC584" modified="2016-02-17" version="1">MLDPGSNRELPPIPAKRYFTIGEVSELCDVKPHVLRYWETEFPTLNPVKRRGNRRYYQRHEVLMVRQIRGLLYEQGYTIGGARLRLEGEAAKDESALSSQIVKQVRMELEEVLQLLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK42</accession>
    <name>A0A0S2DK42_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3669</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948457.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59013">
        <property type="protein sequence ID" value="ALN59013"/>
        <property type="gene ID" value="GLE_3669"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3669"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3613"/>
    <dbReference type="OrthoDB" id="2215314at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="200" mass="21320" checksum="AF54D26A2F86CAC0" modified="2016-02-17" version="1">MCMWIMVGLDEWIVVDGRGKRQDWPVRPPLAAEVTASLATHGLSGCVAVALGWSSGHIGLGHVFSGCTDGQGQPPGPDTWNGPGGYLERLEHALDASQAAIPGASQDRYRDAMLVYSEDTPTRTVELLEQWLRGKGFAVSRDAGQGGRDVIAGRTQDEDMSVVGSGAHAQYFVSSDLHYGPGGHMTVCEALSKRAMPADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK49</accession>
    <name>A0A0S2DK49_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948296.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58785">
        <property type="protein sequence ID" value="ALN58785"/>
        <property type="gene ID" value="GLE_3440"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3440"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3390"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595275" evidence="1">
        <location>
            <begin position="23"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="75" mass="7524" checksum="A13B2884EED5476A" modified="2016-02-17" version="1">MRDTTMAALALLALAACGAAWAGEGNSGTDRGKQAKYTPVICRTGENLVAVPQADGSLQWTCASTSVSSPAPQAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKM6</accession>
    <name>A0A0S2DKM6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59104">
        <property type="protein sequence ID" value="ALN59104"/>
        <property type="gene ID" value="GLE_3760"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3760"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3704"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="39" mass="4122" checksum="45653A3C156C95CE" modified="2016-02-17" version="1">MGGPSGPTLSDPIRSDPIRCDPMRSDAMPHGDLSGQRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKS8</accession>
    <name>A0A0S2DKS8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribose-phosphate pyrophosphokinase</fullName>
            <shortName evidence="6">RPPK</shortName>
            <ecNumber evidence="6">2.7.6.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">5-phospho-D-ribosyl alpha-1-diphosphate</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Phosphoribosyl diphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Phosphoribosyl pyrophosphate synthase</fullName>
            <shortName evidence="6">P-Rib-PP synthase</shortName>
            <shortName evidence="6">PRPP synthase</shortName>
            <shortName evidence="6">PRPPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">prs</name>
        <name evidence="9" type="ORF">BV903_21150</name>
        <name evidence="11" type="ORF">D9T17_09320</name>
        <name evidence="10" type="ORF">FE772_18760</name>
        <name evidence="8" type="ORF">GLE_3809</name>
    </gene>
    <organism evidence="8 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 12">C3</strain>
        </source>
    </reference>
    <reference evidence="9 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">OH11</strain>
        </source>
    </reference>
    <reference evidence="10 15" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15609"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 2 Mg(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.1" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000067">
        <property type="protein sequence ID" value="OPD61945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000023">
        <property type="protein sequence ID" value="ROU07165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948571.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3809"/>
    <dbReference type="EnsemblBacteria" id="ALN59152">
        <property type="protein sequence ID" value="ALN59152"/>
        <property type="gene ID" value="GLE_3809"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61945">
        <property type="protein sequence ID" value="OPD61945"/>
        <property type="gene ID" value="BV903_21150"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3809"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3752"/>
    <dbReference type="OMA" id="FGWARQD"/>
    <dbReference type="OrthoDB" id="1011035at2"/>
    <dbReference type="UniPathway" id="UPA00087">
        <property type="reaction ID" value="UER00172"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009165">
        <property type="term" value="P:nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009156">
        <property type="term" value="P:ribonucleoside monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00583_B">
        <property type="entry name" value="RibP_PPkinase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000842">
        <property type="entry name" value="PRib_PP_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037515">
        <property type="entry name" value="Rib-P_diPkinase_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="PTHR10210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00114">
        <property type="entry name" value="PRPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran_N" evidence="7">
        <location>
            <begin position="8"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Ribose-5-phosphate binding" evidence="6">
        <location>
            <begin position="228"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="40"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="99"/>
            <end position="100"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD61945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROU07165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="319" mass="34209" checksum="AF8FF79FD465BE26" modified="2016-02-17" version="1">MQNDRNLLVFSGNANRPLAQAVCKELGIRLGKALVGRFSDGEVQVEIEENVRRQEVFVIQPTNAPTAENFMELLVLIDALKRASVASVTAVVPYFGYARQDRRPRSSRVPITAKVAAKMFGAVGADRVLTVDLHADQIQGFFDIPVDNVYASPLLLADIWRAHGTDNLIVVSPDVGGVVRARAIAKRLDDADLAIIDKRRPRANVATVMNIIGDVSGKTCVLVDDIVDTAGTLCAAAAALKAQGAQKVVAYCTHPVLSGAAIDNVTKSQLDELVVTDTIPLTAAARATGRIRQLSVAELLAETIRRIAFGESVSSLYVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKT3</accession>
    <name>A0A0S2DKT3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">LEA type 2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_09050</name>
        <name evidence="4" type="ORF">FE772_17480</name>
        <name evidence="2" type="ORF">GLE_3551</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000019">
        <property type="protein sequence ID" value="OPD64318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948375.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3551"/>
    <dbReference type="EnsemblBacteria" id="ALN58895">
        <property type="protein sequence ID" value="ALN58895"/>
        <property type="gene ID" value="GLE_3551"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64318">
        <property type="protein sequence ID" value="OPD64318"/>
        <property type="gene ID" value="BV903_09050"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3551"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3495"/>
    <dbReference type="OMA" id="RNMLNMT"/>
    <dbReference type="OrthoDB" id="1738970at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="160" mass="16740" checksum="1927325986A0BC97" modified="2016-02-17" version="1">MKAAVWVRVIGLALLLALLAGCKTGPVRRVSEPAARIQQLTVKADGSWSVDLRIENFSSIPMQFDRLDLQLKLGEENAGQLQAQPALSIGPESADVVTLALKPAGGARIAIADALAGGRSVNYSLAGDIAATPSEAKQRTFQIERSSALSPAPGLPGVMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKZ0</accession>
    <name>A0A0S2DKZ0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3'(2'),5'-bisphosphate nucleotidase CysQ</fullName>
            <ecNumber evidence="7">3.1.3.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">3'-phosphoadenosine 5'-phosphate phosphatase</fullName>
            <shortName evidence="7">PAP phosphatase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 8" type="primary">cysQ</name>
        <name evidence="9" type="ORF">FE772_19355</name>
        <name evidence="8" type="ORF">GLE_3944</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Converts adenosine-3',5'-bisphosphate (PAP) to AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>adenosine 3',5'-bisphosphate + H2O = AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
            <orientation evidence="7">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the inositol monophosphatase superfamily. CysQ family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.7" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948665.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3944"/>
    <dbReference type="EnsemblBacteria" id="ALN59286">
        <property type="protein sequence ID" value="ALN59286"/>
        <property type="gene ID" value="GLE_3944"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3944"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3881"/>
    <dbReference type="OMA" id="SADCYPR"/>
    <dbReference type="OrthoDB" id="1741160at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008441">
        <property type="term" value="F:3'(2'),5'-bisphosphate nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006790">
        <property type="term" value="P:sulfur compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02095">
        <property type="entry name" value="CysQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006240">
        <property type="entry name" value="CysQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01331">
        <property type="entry name" value="bisphos_cysQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="99"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW27474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="279" mass="30006" checksum="D9BA2F0710CEC7A1" modified="2016-02-17" version="1">MNAPAAPVFHADAALVEGAIAIARVAAAAILDIYDGEFAVERKADASPLTAADLAAHHAILAGLARLTPDIPVLSEESADEVGVEQRRGWERLWLVDPLDGTREFVKRNGEFSVNLALIERGEPVFGVVLAPVGGALWHGARGGHAYRRDGDQERRIQVQAPPAQPLRVAASRSHHSQRSDDFLARAHREAPGGIAMVSLGSSLKFCRIAEGSLDLYPRFGPTSEWDTAAGQCVLEAAGGELLDPQGRPFRYNQRDSLLNGDFIALGDTALPWRAWQDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL52</accession>
    <name>A0A0S2DL52_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ADP compounds hydrolase</fullName>
            <ecNumber evidence="3">3.6.1.-</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="4">ADP compounds hydrolase NudE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">nudE</name>
        <name evidence="4" type="ORF">FE772_19360</name>
        <name evidence="3" type="ORF">GLE_3945</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948666.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000038.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3945"/>
    <dbReference type="EnsemblBacteria" id="ALN59287">
        <property type="protein sequence ID" value="ALN59287"/>
        <property type="gene ID" value="GLE_3945"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3945"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3882"/>
    <dbReference type="OMA" id="PGYFASK"/>
    <dbReference type="OrthoDB" id="1831818at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="43"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="205" mass="22883" checksum="819B3A08DCC4037A" modified="2016-02-17" version="1">MSRRLPIVHNVVEHDASGYRMESLDLEFSNGERRRYERLLGRPRAAGPGAVIVVPMLDDETVLLVREYAAGVHRYELGLVKGRIDAGESAVEAADRELKEEAGYGARSLTVLRSLSLAPTYMIHQAYLVLARDLYPERLPGDEPEELDVIPWKLDRLHELILREDFSEGRSIAALFIAREWLRHGEPAPPPAETVDPAAGAEIAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL64</accession>
    <name>A0A0S2DL64_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Type IV pilus assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pilH</name>
        <name evidence="4" type="ORF">FE772_19435</name>
        <name evidence="3" type="ORF">GLE_3961</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948677.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3961"/>
    <dbReference type="EnsemblBacteria" id="ALN59303">
        <property type="protein sequence ID" value="ALN59303"/>
        <property type="gene ID" value="GLE_3961"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3961"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3898"/>
    <dbReference type="OMA" id="SIGEGFQ"/>
    <dbReference type="OrthoDB" id="1729688at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="121" mass="13447" checksum="21DB6154FC60AD64" modified="2016-02-17" version="1">MARILLIEDSATDTAVLTQLLQRNGHEVFAAGSAEDGIEAAKRELPDLVMMDVVLPGMNGFQATRALSRDEQTKQIPVLIVSTKAMETDRAWGMRQGARDYIVKPPREDDLIARIKELLDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLG2</accession>
    <name>A0A0S2DLG2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cobalamin biosynthesis protein CobD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">cobD</name>
        <name evidence="11" type="ORF">GLE_4087</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cell membrane</location>
            <topology evidence="2 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the CobD/CbiB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948772.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4087"/>
    <dbReference type="EnsemblBacteria" id="ALN59429">
        <property type="protein sequence ID" value="ALN59429"/>
        <property type="gene ID" value="GLE_4087"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4087"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4029"/>
    <dbReference type="OMA" id="WGYRNER"/>
    <dbReference type="OrthoDB" id="2029688at2"/>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015420">
        <property type="term" value="F:ABC-type vitamin B12 transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048472">
        <property type="term" value="F:threonine-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00024">
        <property type="entry name" value="CobD_CbiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031347">
        <property type="entry name" value="AmpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004485">
        <property type="entry name" value="Cobalamin_biosynth_CobD/CbiB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34308">
        <property type="entry name" value="PTHR34308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17113">
        <property type="entry name" value="AmpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03186">
        <property type="entry name" value="CobD_Cbib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00380">
        <property type="entry name" value="cobD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 10" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="11" id="KW-0436">Ligase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="292"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN59429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="312" mass="32875" checksum="DC878A307999715B" modified="2016-02-17" version="1">MSAQALAWTMLGGVLLDAALGEPRRAHPLVAFGRLARALETALHADSRARGLAAWTLATLPLSAAAGWLHCALWQWSAWAGGAFAALALYFAVGLRSLREHAVPVADALDAGRLEDARAAVGRIVSRDAHALDAERVAAAATESVLENGSDAVFAALFWFALLGPAGAVLYRLSNTLDAMWGYRGERYERFGWAAARIDDALNWVPARLTALTYAALGDGARALRCWRAQAPRWDSPNAGPVMAAGAGALGVRLGGDAPYRGVWESRPQLGEGAAPDAGSIRRALALVERGTALWLLAVAVAAFALAGWRHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLH8</accession>
    <name>A0A0S2DLH8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Purine nucleoside phosphorylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLE_4103</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>adenosine + H(+) + H2O = inosine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:24408"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.4"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:24409"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>adenosine + phosphate = adenine + alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:27642"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:27643"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>inosine + phosphate = alpha-D-ribose 1-phosphate + hypoxanthine</text>
            <dbReference type="Rhea" id="RHEA:27646"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:27647"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>phosphate + S-methyl-5'-thioadenosine = adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11852"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58533"/>
            <dbReference type="EC" id="2.4.2.28"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="3">
            <dbReference type="Rhea" id="RHEA:11853"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="5 9">Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948785.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4103"/>
    <dbReference type="EnsemblBacteria" id="ALN59445">
        <property type="protein sequence ID" value="ALN59445"/>
        <property type="gene ID" value="GLE_4103"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4103"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4045"/>
    <dbReference type="OMA" id="CFADCVP"/>
    <dbReference type="OrthoDB" id="1393323at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004000">
        <property type="term" value="F:adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017061">
        <property type="term" value="F:S-methyl-5-thioadenosine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16833">
        <property type="entry name" value="YfiH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003730">
        <property type="entry name" value="Cu_polyphenol_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038371">
        <property type="entry name" value="Cu_polyphenol_OxRdtase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011324">
        <property type="entry name" value="Cytotoxic_necrot_fac-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30616">
        <property type="entry name" value="PTHR30616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02578">
        <property type="entry name" value="Cu-oxidase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64438">
        <property type="entry name" value="SSF64438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00726">
        <property type="entry name" value="TIGR00726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="263" mass="27920" checksum="0AAAAD30FA4041FE" modified="2016-02-17" version="1">MTEPTANPWIDADWPAPPGVRGFATVRRGLGVSQAPFDAFNLGTLYGEQRDDPAAVRRNRELLAQAAGLPSAPRWLHQVHGAGVVRFDGESAAGEAGGGEPEADAAVTSTPGTVLAILTADCLPVLFAADDGSEVGAAHAGWRGLADGVLEATVAAMRSEPARLRAWLGPAAGPQRYEIGAEVRDAFLAVDAAADAAFAATRPGHWRVDLYALARQRLARAGLRADHIRGGGLCTISEPDRFFSHRRDRRTGRMATLVWMQTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLI1</accession>
    <name>A0A0S2DLI1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Alginate biosynthesis transcriptional regulatory protein AlgB</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="10">Sigma-54-dependent Fis family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">algB</name>
        <name evidence="10" type="ORF">FE772_20620</name>
        <name evidence="9" type="ORF">GLE_4206</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948869.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4206"/>
    <dbReference type="EnsemblBacteria" id="ALN59547">
        <property type="protein sequence ID" value="ALN59547"/>
        <property type="gene ID" value="GLE_4206"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4206"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4148"/>
    <dbReference type="OMA" id="PTNSRVM"/>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="21"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="7">
        <location>
            <begin position="166"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN59547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="474" mass="51824" checksum="FC595EAD1D0FD165" modified="2016-02-17" version="1">MDDAAVSHSPRKPARAAPPRRVLIVEDDADVAQALRLLLVSDDYQADIAASPDEAAARIESAQYAAAIVDMNYRRDTTSGGEGLQLIARLRAAAPQLPVLAMTAWASVGLAVEAMRVGAADFIEKPWSNVRLLQVLATQIALHRSHLNEQRLSAAQTLLLAHDGEFVAESPSMRAAVESLRRIAGTDANVLLLGENGTGKTLIAQKLHEWSPRAARAFVKVNVGALAPGVFESELFGHVRGAYTDAKSERAGRFELADGGSLFLDEIGTVPAAQQAALLRVVEDGEFERVGSSRTQRADVRLIAATNLDLAQEVRESRFRQDLLYRLNTFEITLPPLRERDTDIVPLARLYLAQAAARYRREPPVLSAAAERALLRYPWPGNVRELAHTMERAALLARGAQLDAAELQLRGGGADGDEPDWSRITLEQAEARLIRQALERHGGNLQRAADQLGITRQSLYRRLEKHGLSAPEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLI4</accession>
    <name>A0A0S2DLI4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3838</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59181">
        <property type="protein sequence ID" value="ALN59181"/>
        <property type="gene ID" value="GLE_3838"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3838"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="60" mass="6799" checksum="5ACB2E07A5FA50AE" modified="2016-02-17" version="1">MRFHGKRSWVGRLRRMLRHRRANAVDGTACASRTSRGLAARESAFEPYGGERSDAPGIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLI9</accession>
    <name>A0A0S2DLI9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948766.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4080"/>
    <dbReference type="EnsemblBacteria" id="ALN59422">
        <property type="protein sequence ID" value="ALN59422"/>
        <property type="gene ID" value="GLE_4080"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4080"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4022"/>
    <dbReference type="OMA" id="YIERNIC"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010499">
        <property type="entry name" value="AraC_E-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029442">
        <property type="entry name" value="GyrI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06445">
        <property type="entry name" value="GyrI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00871">
        <property type="entry name" value="AraC_E_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="68"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="348" mass="36875" checksum="1C25E08B387BFA00" modified="2016-02-17" version="1">MPPVKDSPAAASVADTPAVAAPAAHAVEAHAAPATVVAAAPESGRTAAAPARAALKPGTRDAHHRRIQRAVALIEQAIAAGEEPPELGRLAEAAAFSPFHFHRVYRAMTGETTGQTVARLRLLQGLRVLADGGRSVTDAALAVGYQTPQAFTRALRQGVGGTPSELRAEPERLWREIDRLAQPPAPEHGEAAPLRVEVVSVEPFQVAALRVTGAYPEQNQGYGRLFGWAAQNGLLDSLRGLYGIPLDDRRDVPPQACAFDCMLALGAPFGADAGEGIRLQVLGGGRYARVRLVGAFDGLEALTDALLARWLPESGESLRDAPLFHEYLDDPDETPEAVLRTDIYLPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLW3</accession>
    <name>A0A0S2DLW3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cystathionine gamma-synthase</fullName>
            <ecNumber evidence="6">2.5.1.48</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Methionine gamma-lyase</fullName>
            <ecNumber evidence="5">4.4.1.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">mdeA</name>
        <name evidence="6" type="ORF">FE772_20810</name>
        <name evidence="5" type="ORF">GLE_4248</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.48" evidence="6"/>
    <dbReference type="EC" id="4.4.1.11" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948903.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4248"/>
    <dbReference type="EnsemblBacteria" id="ALN59589">
        <property type="protein sequence ID" value="ALN59589"/>
        <property type="gene ID" value="GLE_4248"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4248"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4189"/>
    <dbReference type="OMA" id="MQTKLIH"/>
    <dbReference type="OrthoDB" id="637281at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003962">
        <property type="term" value="F:cystathionine gamma-synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102028">
        <property type="term" value="F:cystathionine gamma-synthase activity (acts on O-phosphohomoserine)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018826">
        <property type="term" value="F:methionine gamma-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="PTHR11808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW27716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="393" mass="42465" checksum="79705F78F14D3DBD" modified="2016-02-17" version="1">MSHQPPQDGSRKPGLGTLAIHAGQSPDPSTGAVMPPIYATSTYAQSSPGQHQGFEYSRSHNPTRFAYERCIAGLEGGSRGYAFASGLAATSTILETLDAGSHVIAMDDVYGGTYRLFERVRRRSAGLDFSWVDLSDAAAFEAAIRPETKLVWIETPTNPLLKLVDVAQIAEIARKRGLIVVVDNTFSSPILQRPLELGAHIVMHSATKYLNGHSDIVGGIAVVGDAPELEEQLTFLQNAVGGIQGPFDSFLALRGLKTLHLRMKAHCENAQALAEWLETHPNVEKVLYPGLKSHPQHELAKRQMHGFGGMISLYVKGGMDGARRMMERCHLFTIAESLGGVESLVNHPAVMTHASIPPDRRAALGIGDNLVRLSVGVEDVADLRDELERALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM24</accession>
    <name>A0A0S2DM24_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 7">30S ribosomal protein S9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">rpsI</name>
        <name evidence="9" type="ORF">BV903_04515</name>
        <name evidence="11" type="ORF">D9T17_07525</name>
        <name evidence="10" type="ORF">FE772_20860</name>
        <name evidence="8" type="ORF">GLE_4259</name>
    </gene>
    <organism evidence="8 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 12">C3</strain>
        </source>
    </reference>
    <reference evidence="9 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">OH11</strain>
        </source>
    </reference>
    <reference evidence="10 15" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 15">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000008">
        <property type="protein sequence ID" value="OPD65187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000020">
        <property type="protein sequence ID" value="ROU07625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948911.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000020.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4259"/>
    <dbReference type="EnsemblBacteria" id="ALN59600">
        <property type="protein sequence ID" value="ALN59600"/>
        <property type="gene ID" value="GLE_4259"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65187">
        <property type="protein sequence ID" value="OPD65187"/>
        <property type="gene ID" value="BV903_04515"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4259"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4199"/>
    <dbReference type="OMA" id="QWKINGR"/>
    <dbReference type="OrthoDB" id="1766414at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00532_B">
        <property type="entry name" value="Ribosomal_S9_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000754">
        <property type="entry name" value="Ribosomal_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023035">
        <property type="entry name" value="Ribosomal_S9_bac/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020574">
        <property type="entry name" value="Ribosomal_S9_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569">
        <property type="entry name" value="PTHR21569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00380">
        <property type="entry name" value="Ribosomal_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00360">
        <property type="entry name" value="RIBOSOMAL_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD65187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROU07625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="130" mass="14587" checksum="075E47D6FBC42D77" modified="2016-02-17" version="1">MAIQQNYGTGRRKSSTARVFLRKGDGKITINQRSLEEFFGRETARMIVRQPLELTQSTDKFDLTITVAGGGITGQAGAIRLGIARALVEYDETLKGELRKAGFMTRDAREVERKKVGLHKARRATQFSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMB4</accession>
    <name>A0A0S2DMB4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adenosylmethionine-8-amino-7-oxononanoate aminotransferase</fullName>
            <ecNumber evidence="4">2.6.1.62</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">7,8-diamino-pelargonic acid aminotransferase</fullName>
            <shortName evidence="4">DAPA AT</shortName>
            <shortName evidence="4">DAPA aminotransferase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">7,8-diaminononanoate synthase</fullName>
            <shortName evidence="4">DANS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Diaminopelargonic acid synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">bioA</name>
        <name evidence="6" type="ORF">GLE_3946</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(8S)-8-amino-7-oxononanoate + S-adenosyl-L-methionine = (7R,8S)-7,8-diammoniononanoate + S-adenosyl-4-methylsulfanyl-2-oxobutanoate</text>
            <dbReference type="Rhea" id="RHEA:16861"/>
            <dbReference type="ChEBI" id="CHEBI:16490"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:149468"/>
            <dbReference type="ChEBI" id="CHEBI:149469"/>
            <dbReference type="EC" id="2.6.1.62"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; biotin biosynthesis; 7,8-diaminononanoate from 8-amino-7-oxononanoate (SAM route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.62" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3946"/>
    <dbReference type="EnsemblBacteria" id="ALN59288">
        <property type="protein sequence ID" value="ALN59288"/>
        <property type="gene ID" value="GLE_3946"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3946"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3883"/>
    <dbReference type="OMA" id="VAVKMCL"/>
    <dbReference type="UniPathway" id="UPA00078">
        <property type="reaction ID" value="UER00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004015">
        <property type="term" value="F:adenosylmethionine-8-amino-7-oxononanoate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00834">
        <property type="entry name" value="BioA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005815">
        <property type="entry name" value="BioA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00508">
        <property type="entry name" value="bioA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="4">
        <location>
            <begin position="128"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="4">
        <location>
            <begin position="331"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="425"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM" evidence="4">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="464" mass="50570" checksum="02DEA0113706E9B1" modified="2016-02-17" version="1">MLAEPGNAAADAWRERDLNVLWHPCTQMREHPHTLPLLPVASGRGPWLIGQDGHRYLDAISSWWTNIFGHAEPRIAAAIAEQARTLEHVILAGVSHPPAVELAERLLAIAPRQAGRAPLAKVFYADNGSAGVEVALKMAFHWFRNRGEDRRTKFVALENGYHGETLGALAVGDIPLYRRIYAPLLIESLFAPSPDAYECEPGQSPAERARQAAQALRELLERHAGQVCAMILEPRVQCAGGMRMHDPEYLRLAREICDEHGVFLIADEIAVGFGRTGTMFASEQAGVMPDLLCLSKGLTGGSLPLAAVLATQSIYDGFLDDSRERAFLHSHSYTGNPLACAAALASLAIFAEDDVIERNRATSARMAELAAPLGAHAHVAELRQAGMIVAFELTRGGDKRTPFDPAARIGLRAYRAALQRGVLLRPLGDVLYWMPPYCVDEDALQLLARTTREAIDHAIAEADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMJ4</accession>
    <name>A0A0S2DMJ4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Periplasmic serine endoprotease DegP-like</fullName>
            <ecNumber evidence="4">3.4.21.107</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BV903_03225</name>
        <name evidence="6" type="ORF">GLE_4451</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">B25</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>Acts on substrates that are at least partially unfolded. The cleavage site P1 residue is normally between a pair of hydrophobic residues, such as Val-|-Val.</text>
            <dbReference type="EC" id="3.4.21.107"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase S1C family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.107" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000006">
        <property type="protein sequence ID" value="OPD65320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949065.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4451"/>
    <dbReference type="EnsemblBacteria" id="ALN59792">
        <property type="protein sequence ID" value="ALN59792"/>
        <property type="gene ID" value="GLE_4451"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65320">
        <property type="protein sequence ID" value="OPD65320"/>
        <property type="gene ID" value="BV903_03225"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4451"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4388"/>
    <dbReference type="OMA" id="HAGPYDD"/>
    <dbReference type="OrthoDB" id="741829at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011782">
        <property type="entry name" value="Pept_S1C_Do"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02037">
        <property type="entry name" value="degP_htrA_DO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010594380" description="Periplasmic serine endoprotease DegP-like" evidence="4">
        <location>
            <begin position="21"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="5">
        <location>
            <begin position="268"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR611782-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD65320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="479" mass="49549" checksum="CE89662DEEA089CE" modified="2016-02-17" version="1">MRPLPTLLTLALAAAFGGFAATAVREGLQAPAQAAPPPIPSITVPAAAALPASVAGQALPSLAPMLQRVTPAVVSVHTKQTVRIRNPFANDPIFRRMFPNIPQERINESLGSGVIVDAKNGYVLTNHHVIEGADEVSVTLADGRTVKAEFLGSDPDTDVALMRIPAQNLSAISLADSDGLRVGDFVVAVGNPFGIGQTVTSGIVSAVGRSGLRGLGYQNFIQTDASINPGNSGGALVNLNGELVGINTASFNPQGSMAGNIGLGFAIPVNLARNIKDQLIANNGVVRRGTLGLESQDVTPQLAAALKLAEPRGALVSRVFAGSAAAAAGLRPGDVILSANGQRVDGRDALRNFEGLQSIGSKIALEVRRDGQALQLDASLREQPRSMPGADLDPRLAGATFGELPERLRQSGLSGVVVESVTRGSRAAANDLRKDDIVLAASSGNFDDLPGFRASFTRAPAQLILRVQRGNGVGNLAIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMM3</accession>
    <name>A0A0S2DMM3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HAD family hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase-like hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_21300</name>
        <name evidence="1" type="ORF">GLE_4358</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4358"/>
    <dbReference type="EnsemblBacteria" id="ALN59699">
        <property type="protein sequence ID" value="ALN59699"/>
        <property type="gene ID" value="GLE_4358"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4358"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4297"/>
    <dbReference type="OMA" id="DDTLWVN"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="236" mass="26006" checksum="CA50993BB8E31A57" modified="2016-02-17" version="1">MIGFDADDTLWRSQDYFDQAQLDFERIVGRYVDLGDARLHERLYEIEKNNIGVFGYGVKGMTLSMIEAAVAITGQRIAAADLHRIVELGKDLLRHPVEMLPGIPEAVAAIAADFEIVLITKGDLFHQEAKVKQCGLADLFRRIEIVSEKDAGTYARLLREFGLPAAQFAMIGNSLRSDIAPVLDLGGWGIHMPYHTTWAHETEAEVAADAPRLRRVAGAAELPQAVRELARAAQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMX0</accession>
    <name>A0A0S2DMX0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">(2Fe-2S)-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">2Fe-2S iron-sulfur cluster binding domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_22275</name>
        <name evidence="3" type="ORF">GLE_4565</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4565"/>
    <dbReference type="EnsemblBacteria" id="ALN59906">
        <property type="protein sequence ID" value="ALN59906"/>
        <property type="gene ID" value="GLE_4565"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4565"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4501"/>
    <dbReference type="OMA" id="EHDVPQC"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="SSF47741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="178" mass="18577" checksum="87208BCAC725A61C" modified="2016-02-17" version="1">MKLNVNGIDHDVDAPPDMPLLWVLRDLLHLTGTKFGCGIAQCGACTVHVDGAPRRACVTPAATVQGRKVVTIEGLGRDGPHPVQRAWAEIDVVQCGYCQSGQIMSAAALLGKIPQPTDTDIDQALSGNICRCGTYPRIRAAVHRAAQIAGGGATAFDPPTAASAVPLPLPVLRNVETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMX9</accession>
    <name>A0A0S2DMX9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MarR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_22410</name>
        <name evidence="2" type="ORF">GLE_4593</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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            <end position="149"/>
        </location>
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        </source>
    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
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    </evidence>
    <sequence length="155" mass="17024" checksum="1C79ECA625DD7DB1" modified="2016-02-17" version="1">MKTRTAPAHPPKPTLLLDDQLCFALYSTGLALNKVYRKLLGKLELTYPQYLAMMVLWERDGVTVSEIGERLFLDSATLTPLLKRLEAAGLLTRTRAASDERQVVIELTKAGRALKAKARSVPEGMGCALEDCSIDELTALKAQLESLRASLIAHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMZ1</accession>
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        <submittedName>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
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        <property type="gene ID" value="GLE_4650"/>
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    <dbReference type="KEGG" id="lez:GLE_4650"/>
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        <property type="component" value="Chromosome"/>
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            <end position="77"/>
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        <location>
            <begin position="167"/>
            <end position="212"/>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="212" mass="22838" checksum="F5858101F0A4712F" modified="2016-02-17" version="1">MRDDRYPIACDDDTLDAIKAAMQRSDEEALALLDAAVSRHPADARLALLRGSVYASQGAYPQAFADLSQAVVMAPELYAARFMLGYLELCHRGAAQAIAVWHPLTRLGEHEALGDFARGLTLLVTGQPEQARAFLQRGLEGNREHPELSPFVQSLIEKSHEIVAADEPAPVPGFGAVPAAAETDRDTGDGADEDLGNGSHLLLGGYLDRRDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN71</accession>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the alkaline phosphatase family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ALN59743">
        <property type="protein sequence ID" value="ALN59743"/>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-EC"/>
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    </dbReference>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW27839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="554" mass="59243" checksum="58035DAD67AD0742" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNJ1</accession>
    <name>A0A0S2DNJ1_LYSEN</name>
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            <fullName evidence="4">Amidohydrolase</fullName>
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        <submittedName>
            <fullName evidence="3">Amidohydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_23350</name>
        <name evidence="3" type="ORF">GLE_4805</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN60146">
        <property type="protein sequence ID" value="ALN60146"/>
        <property type="gene ID" value="GLE_4805"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4805"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Amidohydro-rel"/>
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        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
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        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726686" evidence="1">
        <location>
            <begin position="32"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="299"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="438" mass="45263" checksum="4FC8B4EBA83A9E37" modified="2016-02-17" version="1">MGVAMSNPRKARLARTALAAALLCASFAASAQNLLIRNATVHTASAQGSLENADVLVSGGVVRAIGKGLSAPAGAQVIDAAGKPVTPTLFGGITEIGLEEVSGEKSTVDQTVALGADTKEMTVRPEFDVTLAYNPDSVLIPVTRIEGIGWTLLGAGTATGGSIVAGQGGVERLDGGADPIGPRVLFVRLGKDSLGLSGSSRAAQWMILDQLIDETRGRITPDNHAALLTPAGRAALQKYFGGGGRIVFGVDRAADIRQLLRWSSKHQLRIAIAGGAEAWRLAPQLAAAKVPVFVNPLSNLPSDFDQVGASMENAARLRAAGVAVGFSEGGASHNARKVRQLAGNAVAAGLPWADGLAGLTRVPAEAFGVAGEVGAIAPGKRADLVLWSGDPLDVASVALQVWMDGRAIQMRSRQTELRDRYLHPDNGLPRAYPLPAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNK0</accession>
    <name>A0A0S2DNK0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_03660</name>
        <name evidence="2" type="ORF">GLE_4546</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000006">
        <property type="protein sequence ID" value="OPD65392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59887">
        <property type="protein sequence ID" value="ALN59887"/>
        <property type="gene ID" value="GLE_4546"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65392">
        <property type="protein sequence ID" value="OPD65392"/>
        <property type="gene ID" value="BV903_03660"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4546"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4482"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD65392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="62" mass="6196" checksum="3F245A3CF6A21436" modified="2016-02-17" version="1">MFAGLLCMLAGVAVVFLLGLGGLDPAAPAAATPAMVALLPSVALGLSVFALGLWLVFAGRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP91</accession>
    <name>A0A0S2DP91_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GHMP kinases putative ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_5021</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5021"/>
    <dbReference type="EnsemblBacteria" id="ALN60362">
        <property type="protein sequence ID" value="ALN60362"/>
        <property type="gene ID" value="GLE_5021"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5021"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4949"/>
    <dbReference type="OMA" id="VMFAESV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012363">
        <property type="entry name" value="PduX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43527:SF1">
        <property type="entry name" value="PTHR43527:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033887">
        <property type="entry name" value="PduX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="2">
        <location>
            <begin position="111"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="314" mass="34857" checksum="A27670636DDEBD10" modified="2016-02-17" version="1">MLQRTESRDRPALEPASAAAVQAPQAALRVACSGVCHGTLGELWQGPCEHEGELQIGLISLPVRRYSWMHFLPGEDGDIKRDLAGKDKCRRAIEAYLQLHAVSLPPGRFSHDSELPTGKGMASSTADLVATVRCLDRVFGLRTTHEQLTALLRPIERSDSVFLDRYALYLSGRQRVLREFAHAPRLHACYIDEGGTVETEKLAEPLLRHYRRHRSSYRSHLDLALEAFERGDAVAVCEVATRSAQLAQWVTPKAHLDILLRHRRELRADGLVIAHTGSLLGYLFAQRPDSAQLGEVSAFFAGLGRTCRLIETGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPD4</accession>
    <name>A0A0S2DPD4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4963</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60304">
        <property type="protein sequence ID" value="ALN60304"/>
        <property type="gene ID" value="GLE_4963"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4963"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4890"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="46" mass="4915" checksum="3FD8BAB8CE07E389" modified="2016-02-17" version="1">MKKQAATVKPAAKPANAALKLGEVRKQAPAQAAYRASTCIRIYCIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPD5</accession>
    <name>A0A0S2DPD5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 10">Uracil-DNA glycosylase</fullName>
            <shortName evidence="8">UDG</shortName>
            <ecNumber evidence="4 8 10">3.2.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">ung</name>
        <name evidence="13" type="ORF">FE772_23840</name>
        <name evidence="12" type="ORF">GLE_4912</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">C3</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8 10">Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 10">
            <text>Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.</text>
            <dbReference type="EC" id="3.2.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 10">Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.27" evidence="4 8 10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949410.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4912"/>
    <dbReference type="EnsemblBacteria" id="ALN60253">
        <property type="protein sequence ID" value="ALN60253"/>
        <property type="gene ID" value="GLE_4912"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4912"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4842"/>
    <dbReference type="OMA" id="PDNGYLM"/>
    <dbReference type="OrthoDB" id="1260295at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd10027">
        <property type="entry name" value="UDG-F1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00148">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002043">
        <property type="entry name" value="UDG_fam1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018085">
        <property type="entry name" value="Ura-DNA_Glyclase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264">
        <property type="entry name" value="PTHR11264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00628">
        <property type="entry name" value="ung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00130">
        <property type="entry name" value="U_DNA_GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="11">
        <location>
            <begin position="56"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN60253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW28229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="234" mass="25880" checksum="F9675BE88AA4140D" modified="2016-02-17" version="1">MSDGDRDIKLDPSWKSRIGDWFAREDMQSLSRFLRERKAAGARIFPPGPQIFSAFDATAFDQVKVVILGQDPYHGQGQAHGLCFSVQPGVAVPPSLDNIFKEIHRDLGIARPDHGCLLPWARQGVLLLNAVLTVEEGRAGAHQGKGWEGFTDHAVDVLNREREGLVFLLWGSYAQAKGKVIDPRRHRVLKAPHPSPLSAHRGFIGCGHFSAANEYLQRNGQTPIDWALPPRSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPD6</accession>
    <name>A0A0S2DPD6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_16590</name>
        <name evidence="3" type="ORF">FE772_24570</name>
        <name evidence="1" type="ORF">GLE_5069</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000044">
        <property type="protein sequence ID" value="OPD62790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949529.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000044.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60410">
        <property type="protein sequence ID" value="ALN60410"/>
        <property type="gene ID" value="GLE_5069"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62790">
        <property type="protein sequence ID" value="OPD62790"/>
        <property type="gene ID" value="BV903_16590"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5069"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4996"/>
    <dbReference type="OrthoDB" id="1587491at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD62790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="154" mass="16353" checksum="27E7F44B4FA4A0C5" modified="2016-02-17" version="1">MKNIEVFSIATARICATALEQHPVVARFNAEESARHLPGLDPTNREAMAQAVLACGATFEWLLDEGYVRSTACVKESLNGVAFVHVALRYRLTEKGLAILGAHASSNDETKTIGERLIAAVKLGGAERIKESVKLMIGAGAGTHAARPAMQAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPF3</accession>
    <name>A0A0S2DPF3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">EscS/YscS/HrcS family type III secretion system export apparatus protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Type III secretion family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BV903_11160</name>
        <name evidence="9" type="ORF">GLE_5121</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">B25</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FliQ/MopD/SpaQ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000026">
        <property type="protein sequence ID" value="OPD63858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5121"/>
    <dbReference type="EnsemblBacteria" id="ALN60462">
        <property type="protein sequence ID" value="ALN60462"/>
        <property type="gene ID" value="GLE_5121"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63858">
        <property type="protein sequence ID" value="OPD63858"/>
        <property type="gene ID" value="BV903_11160"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5121"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5046"/>
    <dbReference type="OMA" id="WIGVELM"/>
    <dbReference type="OrthoDB" id="1939288at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002191">
        <property type="entry name" value="Bac_export_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006306">
        <property type="entry name" value="T3SS_HrpO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34040">
        <property type="entry name" value="PTHR34040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01313">
        <property type="entry name" value="Bac_export_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004669">
        <property type="entry name" value="FliQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00952">
        <property type="entry name" value="TYPE3IMQPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01403">
        <property type="entry name" value="fliQ_rel_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN60462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD63858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="88" mass="9577" checksum="937A8369DAA77E80" modified="2016-02-17" version="1">MGDMLELTKQALWLTLLLSGPPVLAAAVVGLVVAFIQAATQLQEQTFAYAIKFTVIVVTLFVTASMIGGTLYTFADRIFLDFPGMIRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPI1</accession>
    <name>A0A0S2DPI1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase, M16 family</fullName>
            <ecNumber evidence="6">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_5014</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M16 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949487.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5014"/>
    <dbReference type="EnsemblBacteria" id="ALN60355">
        <property type="protein sequence ID" value="ALN60355"/>
        <property type="gene ID" value="GLE_5014"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5014"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4943"/>
    <dbReference type="OMA" id="DDVKTWF"/>
    <dbReference type="OrthoDB" id="1188251at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595376" evidence="3">
        <location>
            <begin position="31"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16" evidence="4">
        <location>
            <begin position="56"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="5">
        <location>
            <begin position="215"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16" evidence="4">
        <location>
            <begin position="527"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="5">
        <location>
            <begin position="682"/>
            <end position="847"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN60355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="956" mass="102384" checksum="D7C3BEE102A175A5" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPL6</accession>
    <name>A0A0S2DPL6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60492">
        <property type="protein sequence ID" value="ALN60492"/>
        <property type="gene ID" value="GLE_5151"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5151"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="89" mass="9705" checksum="FE952520CBE800DC" modified="2016-02-17" version="1">MANSWGESGSRRTSRGGWNRARVPVLAETMLSSKRCRTAAMVARNGSRQRRCGGAARTQRPMIAPAHDGDRDRRRASAAAARRAPQRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPR0</accession>
    <name>A0A0S2DPR0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5096</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60437">
        <property type="protein sequence ID" value="ALN60437"/>
        <property type="gene ID" value="GLE_5096"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5096"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5021"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="44" mass="4780" checksum="3175018EB4390CB7" modified="2016-02-17" version="1">MGLRQSEQRTTNGWRQRQTGFRVSPEWGGFGFAAIRVGASPAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPV4</accession>
    <name>A0A0S2DPV4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MBL fold metallo-hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Metallo-beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_25625</name>
        <name evidence="2" type="ORF">GLE_5301</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949704.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5301"/>
    <dbReference type="EnsemblBacteria" id="ALN60642">
        <property type="protein sequence ID" value="ALN60642"/>
        <property type="gene ID" value="GLE_5301"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5301"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5219"/>
    <dbReference type="OMA" id="NVGPGHT"/>
    <dbReference type="OrthoDB" id="775108at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="33"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="319" mass="35467" checksum="BD745ABBE18F3F91" modified="2016-02-17" version="1">MSKPFASSTDLAAKTETLEVLADGVYALTAEGDPNVGAFEGEDFLVCIEARATPAAARDWLARLREHTDKPVRYLVLTHYHAVRVLGASAFDAEHIVASETTRQLIEERGEQDWASELGRMPRLFKQAEGVPGLTWPTQTFAERHRIELGGDRGALELQFCGRGHTAGDIVVWHDKSKTLFAGDLVEAEAALYTGDAFHFDWSGATLDRVKAFRAQILVGGRGRVARGTEACDAAIEQTREFLRTMIAQVGRVHAAGGGLREAFAAAHDALAPKFGRWPIFEHCLPFDVQRVWDELDGIDWPRIWTMERDREVWAQLQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ17</accession>
    <name>A0A0S2DQ17_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4955</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60296">
        <property type="protein sequence ID" value="ALN60296"/>
        <property type="gene ID" value="GLE_4955"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4955"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4882"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="113" mass="12678" checksum="279AB3CF59ED51AE" modified="2016-02-17" version="1">MVVGVLRREGGARRGRRVRRVFVVVAVSRSRLAPLLQGLRARRVAPTHARRQRATPSFRRKPESILSLPLPLLVLTPEPDAVVPQPRRACAWMRTRAMGQDAPYGAAPRRCEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ36</accession>
    <name>A0A0S2DQ36_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phenylalanine-4-hydroxylase</fullName>
            <ecNumber evidence="5">1.14.16.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Phe-4-monooxygenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">phhA</name>
        <name evidence="15" type="ORF">BV903_23985</name>
        <name evidence="16" type="ORF">FE772_25420</name>
        <name evidence="14" type="ORF">GLE_5254</name>
    </gene>
    <organism evidence="14 17">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">C3</strain>
        </source>
    </reference>
    <reference evidence="15 18" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 18">B25</strain>
        </source>
    </reference>
    <reference evidence="16 19" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 19">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-phenylalanine + O2 = (4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tyrosine</text>
            <dbReference type="Rhea" id="RHEA:20273"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15642"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:59560"/>
            <dbReference type="EC" id="1.14.16.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 1/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.16.1" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000089">
        <property type="protein sequence ID" value="OPD61365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949668.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000089.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5254"/>
    <dbReference type="EnsemblBacteria" id="ALN60595">
        <property type="protein sequence ID" value="ALN60595"/>
        <property type="gene ID" value="GLE_5254"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61365">
        <property type="protein sequence ID" value="OPD61365"/>
        <property type="gene ID" value="BV903_23985"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5254"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5173"/>
    <dbReference type="OMA" id="KQFPVAT"/>
    <dbReference type="OrthoDB" id="1492162at2"/>
    <dbReference type="UniPathway" id="UPA00139">
        <property type="reaction ID" value="UER00337"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004505">
        <property type="term" value="F:phenylalanine 4-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03348">
        <property type="entry name" value="pro_PheOH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.800.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001273">
        <property type="entry name" value="ArAA_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018301">
        <property type="entry name" value="ArAA_hydroxylase_Fe/CU_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036951">
        <property type="entry name" value="ArAA_hydroxylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036329">
        <property type="entry name" value="Aro-AA_hydroxylase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019774">
        <property type="entry name" value="Aromatic-AA_hydroxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005960">
        <property type="entry name" value="Phe-4-hydroxylase_mono"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11473">
        <property type="entry name" value="PTHR11473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00351">
        <property type="entry name" value="Biopterin_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00372">
        <property type="entry name" value="FYWHYDRXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56534">
        <property type="entry name" value="SSF56534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01267">
        <property type="entry name" value="Phe4hydrox_mono"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00367">
        <property type="entry name" value="BH4_AAA_HYDROXYL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51410">
        <property type="entry name" value="BH4_AAA_HYDROXYL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 15" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="8 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BH4_AAA_HYDROXYL_2" evidence="13">
        <location>
            <begin position="1"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN60595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="OPD61365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QCW28492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="296" mass="34053" checksum="C83B0BA1D521AC12" modified="2016-02-17" version="1">MNTTPQRVEHQLTDKGYVPVYTTAVVEQPWSSYSSDDHAVWAQLFERQQKVLVGRASDEFLTAQRAMHMTPDRIPKFDDLNRTLRAHTGWELIGVEGLLPELTFFDHLANRRFPVTWWIRKPEQIDYLSEPDLFHDLFGHVPLLMNPVFADYMQAYGKGGVKAHGIDPDALVHLTRLYWYTVEFGLIKQADGLRIYGSGIVSSKSESIYSLESNAPNRIGFDLERVMRTRYRIDTFQKTYFVIDSFEQLMRATEPDFTPIYQRLREHDSIPAGDVLASDAVFNRGTGEGWLTDGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ65</accession>
    <name>A0A0S2DQ65_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5212</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60553">
        <property type="protein sequence ID" value="ALN60553"/>
        <property type="gene ID" value="GLE_5212"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5212"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="66" mass="6804" checksum="6D19CB8EC136CE29" modified="2016-02-17" version="1">MVEGVGHGIGASGFGKPGCPARARARARARAPFSHARAGPAFSSERDPRLRMPTPGSHSELGTVHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ87</accession>
    <name>A0A0S2DQ87_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Membrane protein insertase YidC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Foldase YidC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11 13">Membrane integrase YidC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Membrane protein YidC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">oxaA</name>
        <name evidence="13" type="synonym">yidC</name>
        <name evidence="15" type="ORF">GLE_5343</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949735.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5343"/>
    <dbReference type="EnsemblBacteria" id="ALN60684">
        <property type="protein sequence ID" value="ALN60684"/>
        <property type="gene ID" value="GLE_5343"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5343"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5259"/>
    <dbReference type="OMA" id="INPVAGC"/>
    <dbReference type="OrthoDB" id="524437at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032977">
        <property type="term" value="F:membrane insertase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01810">
        <property type="entry name" value="YidC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019998">
        <property type="entry name" value="Membr_insert_YidC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028055">
        <property type="entry name" value="Membr_insert_YidC/Oxa1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028053">
        <property type="entry name" value="Membr_insert_YidC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038210">
        <property type="entry name" value="YidC_periplasmic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038221">
        <property type="entry name" value="YidC_periplasmic_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="PTHR12428"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02096">
        <property type="entry name" value="60KD_IMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14849">
        <property type="entry name" value="YidC_periplas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00701">
        <property type="entry name" value="60KDINNERMP"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01900">
        <property type="entry name" value="YIDCPROTEIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03593">
        <property type="entry name" value="yidC_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03592">
        <property type="entry name" value="yidC_oxa1_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 13" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="444"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="485"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="522"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="domain" description="YidC_periplas" evidence="14">
        <location>
            <begin position="83"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF14849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ALN60684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="576" mass="63126" checksum="BD60CC4F4780F499" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ92</accession>
    <name>A0A0S2DQ92_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Amidohydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Thermostable carboxypeptidase 1</fullName>
            <ecNumber evidence="4">3.4.17.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">cpsA1</name>
        <name evidence="5" type="ORF">FE772_00260</name>
        <name evidence="4" type="ORF">GLE_5397</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.4.17.-" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5397"/>
    <dbReference type="EnsemblBacteria" id="ALN60738">
        <property type="protein sequence ID" value="ALN60738"/>
        <property type="gene ID" value="GLE_5397"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5397"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5312"/>
    <dbReference type="OMA" id="GLHNAPE"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017439">
        <property type="entry name" value="Amidohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11014">
        <property type="entry name" value="PTHR11014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005962">
        <property type="entry name" value="Pept_M20D_amidohydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01891">
        <property type="entry name" value="amidohydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242271" evidence="2">
        <location>
            <begin position="20"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="M20_dimer" evidence="3">
        <location>
            <begin position="242"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW24331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="454" mass="47732" checksum="E321CE6FE4768A14" modified="2016-02-17" version="1">MKRPLSVALSCALTCSALAALPLAAIAQTASSQAASSQAAQRPEVAAAAAKVKADVIAWRRDFHQNPELSNREERTAAKVAEHLRKLGLKPRTGIAKHGVVAIVEGGKPGPKIALRADMDALPVTEQVDLPFASKATASFRGETVGVMHACGHDAHTGILLGIADALVAMKKDLPGQVMLVFQPAEEGAPANEEGGASLMLKEGLFKDFQPEAVFGLHVFSTLNAGQLGVRGGPLMAASDRFSIKIKGRQSHGSTPWMGVDPIVAAADVIGSAQTIVSRRTNIAKLPAVVTFGAIKGGIRYNIIPDDVEMIGTIRTFDDGMRQAIFADLKNVAEHVSAAHGAHAEALVPDQDGNPVTYNDPALTARMLPSLKAVAGEANVVEMPLVMGAEDFSYYAKQVPAMFFFVGSTEKGVDPATAPSNHSPKFKLDESSLDLGLRAMLQVTLDYLNAPKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQN6</accession>
    <name>A0A0S2DQN6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_00865</name>
        <name evidence="2" type="ORF">GLE_5530</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949869.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60871">
        <property type="protein sequence ID" value="ALN60871"/>
        <property type="gene ID" value="GLE_5530"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5530"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5448"/>
    <dbReference type="OrthoDB" id="2213314at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033243148" evidence="1">
        <location>
            <begin position="27"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="148" mass="16104" checksum="B02887F337144F85" modified="2016-02-17" version="1">MNFFCKAKLTLAMIAMGALSSTAAIAGEGTASASSGGYSMDIWASPQTVYTPRGGVGSTNIHWTWNRVAGAPPYGCLYVQNPDTGKWQVVQCEHPRNWYTTYIPWIAGGRNTYFRIAVQFDTVTHDQPAFIEYSPSGNTILSVVGVEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQZ1</accession>
    <name>A0A0S2DQZ1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5472</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60813">
        <property type="protein sequence ID" value="ALN60813"/>
        <property type="gene ID" value="GLE_5472"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5472"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5387"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="37" mass="4590" checksum="27848DD0089755CC" modified="2016-02-17" version="1">MQRLPPQPWRYPFKKIFVMNDTCRRHRDPKRVSCSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA48</accession>
    <name>A0A0S2DA48_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pimeloyl-[acyl-carrier protein] methyl ester esterase</fullName>
            <ecNumber evidence="4">3.1.1.85</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Biotin synthesis protein BioH</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Carboxylesterase BioH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">bioH</name>
        <name evidence="7" type="ORF">FE772_01250</name>
        <name evidence="6" type="ORF">GLE_0063</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>6-carboxyhexanoyl-[ACP] methyl ester + H2O = 6-carboxyhexanoyl-[ACP] + H(+) + methanol</text>
            <dbReference type="Rhea" id="RHEA:42700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9955"/>
            <dbReference type="Rhea" id="RHEA-COMP:10186"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:78846"/>
            <dbReference type="ChEBI" id="CHEBI:82735"/>
            <dbReference type="EC" id="3.1.1.85"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; biotin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.85" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945767.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0063"/>
    <dbReference type="EnsemblBacteria" id="ALN55422">
        <property type="protein sequence ID" value="ALN55422"/>
        <property type="gene ID" value="GLE_0063"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0063"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.69"/>
    <dbReference type="OMA" id="KTMGDFF"/>
    <dbReference type="OrthoDB" id="1282004at2"/>
    <dbReference type="UniPathway" id="UPA00078"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01260">
        <property type="entry name" value="Carboxylester"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010076">
        <property type="entry name" value="BioH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01738">
        <property type="entry name" value="bioH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="2 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0719">Serine esterase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="5">
        <location>
            <begin position="19"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="83"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN55422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW24504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="265" mass="28149" checksum="70C755E492ECDF07" modified="2016-02-17" version="1">MYIETAGAPAGSGRPALALIHGWAMHAGLFAPLVERLGEAFTLHLVDLPGHGYAREDATPLDPKALAADLVQRIPDAHWLGWSLGGQVALRAGLDHPERVRGLILIASSPRFVVGDDWPHGVQPSLFRNFGEALGRDFRGTLEGFLALEALGSAKAQEELRHLRQLAFERGDPAPRALQEGLVLLDEFDVRAELPRLRVPSLWISGRRDRLVPAGAMPAAAALAPRGRSEVIASAGHAPFLGATDEVAAAIEAFVAQAPAPAVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAD7</accession>
    <name>A0A0S2DAD7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0156</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55515">
        <property type="protein sequence ID" value="ALN55515"/>
        <property type="gene ID" value="GLE_0156"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0156"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.158"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="60" mass="7006" checksum="D98F5F8C1EC20E34" modified="2016-02-17" version="1">MICSARPRAACEQARQHRDSLPRNAVRNERPRPACAPRRRRHHSPLVEKRRLSARLTTIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAE4</accession>
    <name>A0A0S2DAE4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane usher protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fasD</name>
        <name evidence="3" type="ORF">GLE_0101</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0101"/>
    <dbReference type="EnsemblBacteria" id="ALN55460">
        <property type="protein sequence ID" value="ALN55460"/>
        <property type="gene ID" value="GLE_0101"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0101"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.105"/>
    <dbReference type="OMA" id="LFNYDLY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015473">
        <property type="term" value="F:fimbrial usher porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009297">
        <property type="term" value="P:pilus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000015">
        <property type="entry name" value="Fimb_usher"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042186">
        <property type="entry name" value="FimD_plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025949">
        <property type="entry name" value="PapC-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043142">
        <property type="entry name" value="PapC-like_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30451">
        <property type="entry name" value="PTHR30451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13953">
        <property type="entry name" value="PapC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00577">
        <property type="entry name" value="Usher"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PapC_C" evidence="2">
        <location>
            <begin position="730"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="809" mass="85998" checksum="FFC7635E75C019C3" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAJ4</accession>
    <name>A0A0S2DAJ4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Microbial collagenase</fullName>
            <ecNumber evidence="4">3.4.24.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">GLE_0220</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Digestion of native collagen in the triple helical region at Xaa-|-Gly bonds. With synthetic peptides, a preference is shown for Gly at P3 and P1', Pro and Ala at P2 and P2', and hydroxyproline, Ala or Arg at P3'.</text>
            <dbReference type="EC" id="3.4.24.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="3.4.24.3" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0220"/>
    <dbReference type="EnsemblBacteria" id="ALN55579">
        <property type="protein sequence ID" value="ALN55579"/>
        <property type="gene ID" value="GLE_0220"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0220"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.222"/>
    <dbReference type="OMA" id="DDYANYR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007280">
        <property type="entry name" value="Peptidase_C_arc/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013661">
        <property type="entry name" value="Peptidase_M9_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002169">
        <property type="entry name" value="Peptidase_M9A/M9B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01752">
        <property type="entry name" value="Peptidase_M9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08453">
        <property type="entry name" value="Peptidase_M9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04151">
        <property type="entry name" value="PPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00931">
        <property type="entry name" value="MICOLLPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="8 13" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594787" description="Microbial collagenase" evidence="13">
        <location>
            <begin position="28"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="14">
        <location>
            <begin position="692"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ALN55579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="886" mass="94327" checksum="FF759EAF2D008BC6" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAJ6</accession>
    <name>A0A0S2DAJ6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptidase, M16 family</fullName>
            <ecNumber evidence="8">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_0211</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the peptidase M16 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945876.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0211"/>
    <dbReference type="EnsemblBacteria" id="ALN55570">
        <property type="protein sequence ID" value="ALN55570"/>
        <property type="gene ID" value="GLE_0211"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0211"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.213"/>
    <dbReference type="OMA" id="LWHNYGN"/>
    <dbReference type="OrthoDB" id="1188251at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001431">
        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00143">
        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594840" evidence="5">
        <location>
            <begin position="31"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16" evidence="6">
        <location>
            <begin position="63"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="7">
        <location>
            <begin position="218"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="7">
        <location>
            <begin position="677"/>
            <end position="858"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN55570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="937" mass="100771" checksum="FB54C9C55E66ADAF" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAK8</accession>
    <name>A0A0S2DAK8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AMP-binding enzyme</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Peptide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_01875</name>
        <name evidence="2" type="ORF">GLE_0202</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW24611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_0202"/>
    <dbReference type="EnsemblBacteria" id="ALN55561">
        <property type="protein sequence ID" value="ALN55561"/>
        <property type="gene ID" value="GLE_0202"/>
    </dbReference>
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    <dbReference type="OMA" id="WFCGRKS"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="18"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="553" mass="60042" checksum="873592EFF59DFA23" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAS2</accession>
    <name>A0A0S2DAS2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Thioredoxin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_24405</name>
        <name evidence="5" type="ORF">FE772_02235</name>
        <name evidence="3" type="ORF">GLE_0281</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
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        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000093">
        <property type="protein sequence ID" value="OPD61306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW24663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945924.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000093.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55639">
        <property type="protein sequence ID" value="ALN55639"/>
        <property type="gene ID" value="GLE_0281"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61306">
        <property type="protein sequence ID" value="OPD61306"/>
        <property type="gene ID" value="BV903_24405"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0281"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.280"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13192">
        <property type="entry name" value="Thioredoxin_3"/>
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    </dbReference>
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        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin-like_fold" evidence="2">
        <location>
            <begin position="6"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD61306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW24663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="78" mass="8297" checksum="90AF56C7C7ED7C86" modified="2016-02-17" version="1">MRQKAVFFHAGCPVCVAAEQQVAEAIDRARFEVEVVHLGEASARIAEARAAGVISVPALVLHEQVFHINFGAALSDLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAU7</accession>
    <name>A0A0S2DAU7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0284</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Xanthomonadaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
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    <dbReference type="EnsemblBacteria" id="ALN55642">
        <property type="protein sequence ID" value="ALN55642"/>
        <property type="gene ID" value="GLE_0284"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0284"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.283"/>
    <dbReference type="OMA" id="YKSRFAQ"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR021957">
        <property type="entry name" value="DUF3574"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12098">
        <property type="entry name" value="DUF3574"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594881" evidence="1">
        <location>
            <begin position="22"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="149" mass="16139" checksum="DD9343F75E70F1E7" modified="2016-02-17" version="1">MLRPFSLAIALCALSACASLAPLPVKPGDPSACAERRQDRVLFGMNSPDGPVGEAQWQSFLAEVVTPRFPAGLTVYQAKGQWRGDSGQVEQEDSRAIDVIHADTAEERKRVVEIADEYKRRFKQEAVLIVSSPVRACFAVAAKPSGRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB03</accession>
    <name>A0A0S2DB03_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Peptide deformylase</fullName>
            <shortName evidence="4">PDF</shortName>
            <ecNumber evidence="4">3.5.1.88</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3 4">Polypeptide deformylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 5" type="primary">def</name>
        <name evidence="6" type="ORF">BV903_18940</name>
        <name evidence="7" type="ORF">FE772_02575</name>
        <name evidence="5" type="ORF">GLE_0356</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>H2O + N-terminal N-formyl-L-methionyl-[peptide] = formate + N-terminal L-methionyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:24420"/>
            <dbReference type="Rhea" id="RHEA-COMP:10639"/>
            <dbReference type="Rhea" id="RHEA-COMP:10640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:49298"/>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
            <dbReference type="EC" id="3.5.1.88"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="4">Binds 1 Fe(2+) ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the polypeptide deformylase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.88" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000053">
        <property type="protein sequence ID" value="OPD62365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945975.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000053.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0356"/>
    <dbReference type="EnsemblBacteria" id="ALN55714">
        <property type="protein sequence ID" value="ALN55714"/>
        <property type="gene ID" value="GLE_0356"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62365">
        <property type="protein sequence ID" value="OPD62365"/>
        <property type="gene ID" value="BV903_18940"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0356"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.353"/>
    <dbReference type="OMA" id="VCIQHEI"/>
    <dbReference type="OrthoDB" id="1649129at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042586">
        <property type="term" value="F:peptide deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00487">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00163">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023635">
        <property type="entry name" value="Peptide_deformylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036821">
        <property type="entry name" value="Peptide_deformylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458">
        <property type="entry name" value="PTHR10458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01327">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004749">
        <property type="entry name" value="Pep_def"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01576">
        <property type="entry name" value="PDEFORMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56420">
        <property type="entry name" value="SSF56420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00079">
        <property type="entry name" value="pept_deformyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="4">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00032756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN55714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD62365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW24722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="170" mass="18981" checksum="916A0FED043B8892" modified="2016-02-17" version="1">MALLPILEFPDPRLRTKAAAVDPARVTEPAFQQLLDDMFQTMYECPGIGLAASQVDVHQRFMVIDVSEDKNQPLVFVNPEILERSGEQVYQEGCLSVPGIFADVTRANAITVRAVGRDGQPFELSADGLLAVCIQHEMDHLEGKLFVDYLSPLKREMVRKKLAKQKRLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB25</accession>
    <name>A0A0S2DB25_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 8">Methionyl-tRNA formyltransferase</fullName>
            <ecNumber evidence="4 8">2.1.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">fmt</name>
        <name evidence="12" type="ORF">FE772_02580</name>
        <name evidence="11" type="ORF">GLE_0357</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8">Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(6S)-10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = (6S)-5,6,7,8-tetrahydrofolate + H(+) + N-formyl-L-methionyl-tRNA(fMet)</text>
            <dbReference type="Rhea" id="RHEA:24380"/>
            <dbReference type="Rhea" id="RHEA-COMP:9952"/>
            <dbReference type="Rhea" id="RHEA-COMP:9953"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:78844"/>
            <dbReference type="EC" id="2.1.2.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the Fmt family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.9" evidence="4 8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945976.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0357"/>
    <dbReference type="EnsemblBacteria" id="ALN55715">
        <property type="protein sequence ID" value="ALN55715"/>
        <property type="gene ID" value="GLE_0357"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0357"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.354"/>
    <dbReference type="OMA" id="CCPVVAY"/>
    <dbReference type="OrthoDB" id="2009156at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004479">
        <property type="term" value="F:methionyl-tRNA formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08646">
        <property type="entry name" value="FMT_core_Met-tRNA-FMT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08704">
        <property type="entry name" value="Met_tRNA_FMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00182">
        <property type="entry name" value="Formyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005794">
        <property type="entry name" value="Fmt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005793">
        <property type="entry name" value="Formyl_trans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037022">
        <property type="entry name" value="Formyl_trans_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011034">
        <property type="entry name" value="Formyl_transferase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001555">
        <property type="entry name" value="GART_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044135">
        <property type="entry name" value="Met-tRNA-FMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041711">
        <property type="entry name" value="Met-tRNA-FMT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02911">
        <property type="entry name" value="Formyl_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50486">
        <property type="entry name" value="SSF50486"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="SSF53328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00460">
        <property type="entry name" value="fmt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00373">
        <property type="entry name" value="GART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl_trans_N" evidence="9">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="Formyl_trans_C" evidence="10">
        <location>
            <begin position="203"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Tetrahydrofolate (THF) binding" evidence="8">
        <location>
            <begin position="108"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN55715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW24723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="307" mass="33039" checksum="E0D5EBFB95FB0D5F" modified="2016-02-17" version="1">MRIVFAGTPEFAVPALRAAAQYNEVVAVYTQPDRPAGRGREMALSPVKREALLRGIPVLQPENFKQAVSRKALRALEPDLMVVVAYGLILPQSVLDIPVHGCWNLHASLLPRWRGAAPIQRAIEAGDDETGVCLMRMEKGLDTGPVLLANDTEIGANETGGQLHDRLADIGAQVLRDGLGLLRVGLVPQPYPQPEQGVTYAHKLDKAEARLDWSRPATELANKVRAFNPWPMADALLAGERVRVHGAVALPLAHGAEPGTVLLAGRDGIDVACGDGALRIRVLQREGGKAITAADYLNGRRDLATVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBQ3</accession>
    <name>A0A0S2DBQ3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha-amino acid ester hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0410</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55768">
        <property type="protein sequence ID" value="ALN55768"/>
        <property type="gene ID" value="GLE_0410"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0410"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.407"/>
    <dbReference type="OMA" id="FFFDDFH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005674">
        <property type="entry name" value="CocE/Ser_esterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000383">
        <property type="entry name" value="Xaa-Pro-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013736">
        <property type="entry name" value="Xaa-Pro_dipept_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02129">
        <property type="entry name" value="Peptidase_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08530">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00939">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00976">
        <property type="entry name" value="NonD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594898" evidence="1">
        <location>
            <begin position="32"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="domain" description="PepX_C" evidence="2">
        <location>
            <begin position="378"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="646" mass="72385" checksum="DA6768352E4359D2" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBT6</accession>
    <name>A0A0S2DBT6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0635</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946178.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0635"/>
    <dbReference type="EnsemblBacteria" id="ALN55993">
        <property type="protein sequence ID" value="ALN55993"/>
        <property type="gene ID" value="GLE_0635"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0635"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.624"/>
    <dbReference type="OrthoDB" id="1390844at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="280" mass="29874" checksum="73974104B8D15C98" modified="2016-02-17" version="1">MTRLTRFTDPHAVDLWDTRFRWRSGERLRDRTVDATWQRVASTLAAVGGDSGYWCSRYVAAFGAWQVLPDPRLLRRAGTERAVPPLRAPRAALNAGAFVLDAGSARARFDHDRFAIAAALAVRMLDDAAVAFGADSGLLRLEVGVIGLADALARMGVDYLGDAAPAQAQAIARSLALGCLQGAGRLSRERGARAGGNDLAAAWTARETPAALADALFANRRHARLTRVRPQPALARLANGASDGIEPARGAAEPGPLRAARTRIAAAMQPWIDAPVRTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBV2</accession>
    <name>A0A0S2DBV2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UPF0391 membrane protein BV903_08240</fullName>
        </recommendedName>
    </protein>
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        <name evidence="7" type="ORF">BV903_08240</name>
        <name evidence="9" type="ORF">D9T17_23895</name>
        <name evidence="8" type="ORF">FE772_03945</name>
        <name evidence="6" type="ORF">GLE_0648</name>
    </gene>
    <organism evidence="6 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 10">C3</strain>
        </source>
    </reference>
    <reference evidence="7 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">OH11</strain>
        </source>
    </reference>
    <reference evidence="8 13" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 13">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
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            <topology evidence="5">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the UPF0391 family.</text>
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    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="GLE_0648"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="DUF1328"/>
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    </dbReference>
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        <property type="entry name" value="UCP036466"/>
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    </dbReference>
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            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
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            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ROU04460.1"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="54" mass="5714" checksum="8F053B0D73A200EA" modified="2016-02-17" version="1">MLHYAVVFFVIALIAAVLGFTGIAGAASNIAWILFVVFVVLAIISLLRGRRPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="GLE_0658"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="43" mass="5246" checksum="B36EAA601CB8E7AC" modified="2016-02-17" version="1">MNEVSSSRRRRWGKMKRMFALWEGFRPDAFISGRGDPRHKHRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC58</accession>
    <name>A0A0S2DC58_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytidylyltransferase family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Phosphatidate cytidylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_04465</name>
        <name evidence="2" type="ORF">GLE_0758</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_0758"/>
    <dbReference type="EnsemblBacteria" id="ALN56116">
        <property type="protein sequence ID" value="ALN56116"/>
        <property type="gene ID" value="GLE_0758"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0758"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.746"/>
    <dbReference type="OMA" id="QYVWGKL"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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            <end position="282"/>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="324" mass="36182" checksum="F4680EAF18756946" modified="2016-02-17" version="1">MERAGLDQVVEFVRAQSHPVLLFSGVAAVLLLATLVSEWLRWKTRDKPSAVIANLVARIRAWWVMALVVGAAFAIGRVGMIVLFALVSLFALREFITLTPTRRSDYYALLAAFYVALPLQYWLVYTDWYGLYTLLIPVYAFLLLPILSTVGEDTTRYLERTAKVQWGLMICVFCISHVPALINLKIPGYEGRNLLLVAFLVIVVQSSDVLQYIWGKLCGKRLIAPRLSPSKTVEGFVGGVASATALGAALWWITPFTPWQAAALALVINLMGFYGGLVMSAIKRDRGIKDWGHMIEGHGGVLDRLDSVCFAAPVFFHLIRYWWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCE7</accession>
    <name>A0A0S2DCE7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AraC family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Helix-turn-helix domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, AraC family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_09660</name>
        <name evidence="5" type="ORF">FE772_04865</name>
        <name evidence="3" type="ORF">GLE_0838</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
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    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD64144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946335.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0838"/>
    <dbReference type="EnsemblBacteria" id="ALN56196">
        <property type="protein sequence ID" value="ALN56196"/>
        <property type="gene ID" value="GLE_0838"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64144">
        <property type="protein sequence ID" value="OPD64144"/>
        <property type="gene ID" value="BV903_09660"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="OPD64144.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW25102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="307" mass="34046" checksum="8F03FCC4AD6D5890" modified="2016-02-17" version="1">MEQALWADRGQLLQLDAQDHSAQASCVGVSRLGSAQLSGTHFSIWVQLRGSSWVEAKEGKFRLKRGDWIAFERDSKPVLQADRYGVCIGLNLTPDAIKAMARLADSTLYAGRGRMNRHDARIALRLWRQAHARNGEADTGFDLNALRPILLHLAGVQRELTARIQRCPGRSRSRKRQVFGRLQRARLYLEGNCDRVVRISELAELTSFSSWYFSKTFHSLYEESPQAASARMRLEHAADLLKNTSMMIGEVAAASGFDNCCSFARAFRARFGTSATRYRSAAAAAKAEAARAAVVSAVPLRKLAMAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCI2</accession>
    <name>A0A0S2DCI2_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="2" type="ORF">GLE_0878</name>
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    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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    </organism>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="56" mass="6488" checksum="B293ED570021F085" modified="2016-02-17" version="1">MRGVADRARPALELERLPPQRRSRDAPEPARRRDAPEPARRRDACERTGARWAPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCK9</accession>
    <name>A0A0S2DCK9_LYSEN</name>
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        <submittedName>
            <fullName evidence="7">Sensory box protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_0894</name>
    </gene>
    <organism evidence="7 8">
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            <taxon>Proteobacteria</taxon>
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    <reference evidence="7 8" key="1">
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            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
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    </dbReference>
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        <location>
            <begin position="1"/>
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        </location>
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        </location>
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        <location>
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        </location>
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        <location>
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            <end position="1251"/>
        </location>
    </feature>
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        <location>
            <begin position="1260"/>
            <end position="1514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN56252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1523" mass="168616" checksum="A659E20226D84B7B" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD17</accession>
    <name>A0A0S2DD17_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1064</name>
    </gene>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56422">
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        <property type="gene ID" value="GLE_1064"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="40" mass="4688" checksum="2EF2212AFE880C12" modified="2016-02-17" version="1">MRRRLLLPGLRRRPALSADVPFLSVFVFQPKSQARFHEPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD45</accession>
    <name>A0A0S2DD45_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1112</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="GLE_1112"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="72" mass="8271" checksum="2CEB845BF3BAD704" modified="2016-02-17" version="1">MRPARTTAQRAGFIGACDFEPAMSNRPMRQTRHRRPRHRRARHGNRHQLARPRAIPRRAPRGIAGNADQLAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD89</accession>
    <name>A0A0S2DD89_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RHS repeat protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Rhs family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_06350</name>
        <name evidence="3" type="ORF">GLE_1165</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1165"/>
    <dbReference type="EnsemblBacteria" id="ALN56523">
        <property type="protein sequence ID" value="ALN56523"/>
        <property type="gene ID" value="GLE_1165"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1165"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1150"/>
    <dbReference type="OMA" id="GHQEAHA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045351">
        <property type="entry name" value="DUF6531"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031325">
        <property type="entry name" value="RHS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006530">
        <property type="entry name" value="YD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20148">
        <property type="entry name" value="DUF6531"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05593">
        <property type="entry name" value="RHS_repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01643">
        <property type="entry name" value="YD_repeat_2x"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726528" evidence="1">
        <location>
            <begin position="29"/>
            <end position="1513"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6531" evidence="2">
        <location>
            <begin position="159"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="1513" mass="164882" checksum="944466F6C5088D3B" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDD3</accession>
    <name>A0A0S2DDD3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADP-dependent oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">NADP-dependent oxidoreductase YncB</fullName>
            <ecNumber evidence="2">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yncB</name>
        <name evidence="3" type="ORF">FE772_05785</name>
        <name evidence="2" type="ORF">GLE_1039</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.-.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946481.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1039"/>
    <dbReference type="EnsemblBacteria" id="ALN56397">
        <property type="protein sequence ID" value="ALN56397"/>
        <property type="gene ID" value="GLE_1039"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1039"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1027"/>
    <dbReference type="OMA" id="GKDKCDY"/>
    <dbReference type="OrthoDB" id="474248at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041694">
        <property type="entry name" value="ADH_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045010">
        <property type="entry name" value="MDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205">
        <property type="entry name" value="PTHR43205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16884">
        <property type="entry name" value="ADH_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="21"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="344" mass="36676" checksum="FFBF8BBA99DBBEB1" modified="2016-02-17" version="1">MPQTAAVNRRFVLAAHPQGLPTPQDVRLETGPVPEPGDGQVLLRTLYLSLDPYMRNLMDEVGPVYAPAVPLGEAMVGGTVNRVVASNHPDFKPGDLVLGNAGWQDYALSDGSDLTALGDMAEPSHALGGLGMPGFTAYVGLLDLGQPKPGDTVVVAAATGAVGAVVGQIAKLKGARVVAIVGGEDKRRYALDELGFDVCLDRRDPDFAAQLAQACPDGIDVYFENVGGEVFDAVLPLLNIGARVPVCGIIAHYNDKTAPAGPDRVPLLMSAILQKRIKVQGFIIFDHYEQRFEAFRRDMAEWIGSGALKLREDRVDGLENAPEAFIGLLQGRNFGKLVVRVGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDF9</accession>
    <name>A0A0S2DDF9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lipase chaperone</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Lipase foldase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Lipase helper protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Lipase modulator</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FE772_06315</name>
        <name evidence="15" type="ORF">GLE_1158</name>
    </gene>
    <organism evidence="15 17">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="15 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">C3</strain>
        </source>
    </reference>
    <reference evidence="16 18" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May be involved in the folding of the extracellular lipase during its passage through the periplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
            <orientation evidence="2">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the lipase chaperone family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946561.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1158"/>
    <dbReference type="EnsemblBacteria" id="ALN56516">
        <property type="protein sequence ID" value="ALN56516"/>
        <property type="gene ID" value="GLE_1158"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1158"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1143"/>
    <dbReference type="OMA" id="VETYDAI"/>
    <dbReference type="OrthoDB" id="1337848at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004961">
        <property type="entry name" value="Lipase_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03280">
        <property type="entry name" value="Lipase_chap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="231"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ALN56516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QCW25332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="340" mass="36413" checksum="358D0757B6DAF605" modified="2016-02-17" version="1">MRATALGIAMAIVAVLAIVAVFAVGGLLERPLLSSATVVSSGDGGQLADPDPRAAESRVSTPVAPDRAAAADSLRDTAVDGAATLDALGRPRADRELRRLFDYFLARSGERSPETIRSALALHLHAQLAPPALATVLAWYDAYVALERDSVALAQAAGGAEAGFARVRALRRERLGEELAQAFYAQEEADYELARQRGAARGALLAQQGLDAQARADGLAELDRSAAAEPALQASAQLSDALAQNRRFEREGTDAATRYAQREAQYGAAAAQRLADLDQRRAQWQLRLRSYAAQRQRVLADGGLSETQRRQRLDALLADFDPNERRRVDALARNGGLPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDK1</accession>
    <name>A0A0S2DDK1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tetratricopeptide repeat domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1281</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1281"/>
    <dbReference type="EnsemblBacteria" id="ALN56638">
        <property type="protein sequence ID" value="ALN56638"/>
        <property type="gene ID" value="GLE_1281"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1281"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1264"/>
    <dbReference type="OrthoDB" id="1751461at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="315" mass="34763" checksum="F819074412D730DE" modified="2016-02-17" version="1">MRPHRRILFAMPKPRSARERAELLNEYGHRLGARGEDERALSFYAQAAQADPAWAAPWFNIGLLHKYFGDWTQSLIANREALARDAGHQGACWNLGIAATALRDWRSAREAWQRYGLPIEPGEEPLEVDCGLAPVRLDPDGRGEVVWCDRLDPARARIRNVPLPDSGHRYADIVLNDGAPNGSRRIGEREYPVFDQLELWQASPYATFEAWIETPDPASLAALAQRAHGDHGQAQDWTDSVRHLCRACSLGDADADAAHDHPPLQASGDAAGARWVGVAARDEAAARAVVDDWLHAHPSARLLQWRLAVPAGAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDZ8</accession>
    <name>A0A0S2DDZ8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PadR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, PadR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_07550</name>
        <name evidence="2" type="ORF">GLE_1432</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946771.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56789">
        <property type="protein sequence ID" value="ALN56789"/>
        <property type="gene ID" value="GLE_1432"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1432"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1413"/>
    <dbReference type="OMA" id="YRWEEST"/>
    <dbReference type="OrthoDB" id="1706427at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="24"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="121" mass="13269" checksum="3FEBFF6F39BF9427" modified="2016-02-17" version="1">MTDLDSHLRKFQKELSTGTVSLALLAVLGAAGEPMYGYQIAKRLEREGEGVLSGKQSALYPVLRNLGAAGLLDSHVEPSVTGPPRRYYRITDSGRAVLREWTQAWRATRDSVDSVLQGLEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE08</accession>
    <name>A0A0S2DE08_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Three-Cys-motif partner protein TcmP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">tcmP</name>
        <name evidence="2" type="ORF">FE772_07650</name>
        <name evidence="1" type="ORF">GLE_1455</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56812">
        <property type="protein sequence ID" value="ALN56812"/>
        <property type="gene ID" value="GLE_1455"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1455"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1435"/>
    <dbReference type="OMA" id="DFAIHFS"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031009">
        <property type="entry name" value="Tcm_partner"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04474">
        <property type="entry name" value="tcm_partner"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="275" mass="31221" checksum="CFCCDA3C378186A1" modified="2016-02-17" version="1">MPTKRKEERYEIDLDDGLRRELVGTWVQEKHQRLRYYVDISRAARRKFHGNSTFIDLYCGPGRARIKDTPVIVPGSAVVAASEAARHAAFGKIYIGDISATNLDHCRQRLEQERLSPIIAFEGAAEVTAQAVSRELSPSALHFAFLDPYSVQALPFTVIEALAELPKMDILIHFSIMDMQRNIKALMKAGKLDQFAPGWRDQVDPALRNASALLAVFHYWCGLIRNLGYYVSDNVERVSGTHNQPLYWLVLVSKDKLGERFWDKISNVTPQPRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE96</accession>
    <name>A0A0S2DE96_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Adenylosuccinate synthetase</fullName>
            <shortName evidence="8">AMPSase</shortName>
            <shortName evidence="8">AdSS</shortName>
            <ecNumber evidence="8 10">6.3.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">IMP--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">purA</name>
        <name evidence="12" type="ORF">BV903_21805</name>
        <name evidence="13" type="ORF">FE772_07950</name>
        <name evidence="11" type="ORF">GLE_1516</name>
    </gene>
    <organism evidence="11 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">C3</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">B25</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>GTP + IMP + L-aspartate = GDP + 2 H(+) + N(6)-(1,2-dicarboxyethyl)-AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="6.3.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8 10">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 10">Belongs to the adenylosuccinate synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.4" evidence="8 10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000072">
        <property type="protein sequence ID" value="OPD61812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946841.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000072.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1516"/>
    <dbReference type="EnsemblBacteria" id="ALN56873">
        <property type="protein sequence ID" value="ALN56873"/>
        <property type="gene ID" value="GLE_1516"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61812">
        <property type="protein sequence ID" value="OPD61812"/>
        <property type="gene ID" value="BV903_21805"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1516"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1498"/>
    <dbReference type="OMA" id="FHHAKPI"/>
    <dbReference type="OrthoDB" id="232152at2"/>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004019">
        <property type="term" value="F:adenylosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03108">
        <property type="entry name" value="AdSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00011">
        <property type="entry name" value="Adenylosucc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018220">
        <property type="entry name" value="Adenylosuccin_syn_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033128">
        <property type="entry name" value="Adenylosuccin_syn_Lys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042109">
        <property type="entry name" value="Adenylosuccinate_synth_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042110">
        <property type="entry name" value="Adenylosuccinate_synth_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042111">
        <property type="entry name" value="Adenylosuccinate_synth_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001114">
        <property type="entry name" value="Adenylosuccinate_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11846">
        <property type="entry name" value="PTHR11846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00709">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00788">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00184">
        <property type="entry name" value="purA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01266">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00513">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8 10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8 10" id="KW-0547">Nucleotide-binding</keyword>
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    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
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            <end position="17"/>
        </location>
    </feature>
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        </location>
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            <begin position="300"/>
            <end position="306"/>
        </location>
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            <position position="14"/>
        </location>
    </feature>
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            <position position="42"/>
        </location>
    </feature>
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        </location>
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        <location>
            <begin position="13"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
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        <location>
            <begin position="41"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
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        <location>
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        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
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        <location>
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        </location>
        <ligand>
            <name>IMP</name>
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        </ligand>
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        <location>
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        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
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        <ligand>
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        </ligand>
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        <location>
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        </location>
        <ligand>
            <name>IMP</name>
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        </ligand>
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        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
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        <ligand>
            <name>GTP</name>
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        </ligand>
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        <location>
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        <ligand>
            <name>GTP</name>
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        </ligand>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
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        </source>
    </evidence>
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        </source>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN56873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OPD61812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW25608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="430" mass="46262" checksum="6D81440A683C8A81" modified="2016-02-17" version="1">MGQSVVVLGAQWGDEGKGKIVDLLTEQIGAVVRFQGGHNAGHTLVIGGKKTVLHLIPSGILREGALCLIGNGVVLSPAALRKEIDELEATGVEVRSRLKISPATPLIMPYHIALDQAREKAAGGKAIGTTGRGIGPAYEDKVARRGIRVADLHYPAQLAELLRSALDYHNFVLTKYLGVDAVDYQKTLDEALEFGEYVQPMKSDVAGILHDLRKQGKRVLFEGAQGSLLDIDHGTYPYVTSSNTTVGGALAGTGVGADAIDYVLGIAKAYATRVGGGPFPTELDDEVGQGIRDRGQEYGATTGRPRRCGWIDIVALKRAVAINGITGLCITKLDVLDGMKTLKICIAYEYRGKRTEYAPLDAAGWDECTPVYLEFPGWDENTHGITEWDKLPPAARAYLRALEELAGCPLAIVSTGPDRDHTMVLHDLWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEF2</accession>
    <name>A0A0S2DEF2_LYSEN</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">FE772_08285</name>
        <name evidence="1" type="ORF">GLE_1592</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
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        </lineage>
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    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
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        <property type="gene ID" value="GLE_1592"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="117" mass="13622" checksum="017E379DBFCEF701" modified="2016-02-17" version="1">MQGNTITLYRPVGPNELARLRENAFKRWPPRLPEQPIFYPVTNERYAAEIAERWNVKDSGYGAVTRFEVDAQFMARYPIQKVGGAHHTEWWVPAEELDALNDHIVGLIEIVREFRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEN8</accession>
    <name>A0A0S2DEN8_LYSEN</name>
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        <submittedName>
            <fullName evidence="3 4">FAD-dependent oxidoreductase</fullName>
        </submittedName>
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        <name evidence="4" type="ORF">FE772_07710</name>
        <name evidence="3" type="ORF">GLE_1467</name>
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        <dbReference type="NCBI Taxonomy" id="69"/>
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        </lineage>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ALN56824">
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        <property type="gene ID" value="GLE_1467"/>
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    <dbReference type="KEGG" id="lez:GLE_1467"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1448"/>
    <dbReference type="OMA" id="ATPWMGF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="DAO" evidence="2">
        <location>
            <begin position="20"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="432" mass="46832" checksum="83C1D8B18D725F51" modified="2016-02-17" version="1">MGAAQVHVESADPVGARREDVVIVGAGVIGLACALILLEDGRRVRVIDAGRIGGGSSHGNCGTITPSHATPLAAPGVIAQAIKWVLTPDAPLYLHPKLDPQLWGWLLRFAARCNARDWRASAQAKAALLNDSRERLQEWVARYGLVCEFDGSGVDYVFRSEAGYLHGQHELDLLREFGVGVELIDGGAYEAQDPAFKPGVVGAIRFAHDAVLRPDSYVAELARAVRERGGELQEYCALKDLREDADGVALDTSHGVLLAREAVVALGAWSPKLAEAIGLPALKAAIQPGKGYSITYDRPELLPRRPVVLKEPKVCVTMWDSGYRLGSTMEFSGYDESLNPRRLAALERGAAQFLHQPLGPVERERWYGWRPMSIDDVPLIGRVPGRQRLWIANGHGMMGVSMSAGTGQLLADLIGGRAPAIDPHPYRPERFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF88</accession>
    <name>A0A0S2DF88_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Streptogrisin-C</fullName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">sprC</name>
        <name evidence="10" type="ORF">GLE_1733</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947012.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1733"/>
    <dbReference type="EnsemblBacteria" id="ALN57088">
        <property type="protein sequence ID" value="ALN57088"/>
        <property type="gene ID" value="GLE_1733"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1733"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1710"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.50">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037295">
        <property type="entry name" value="Alpha-lytic_protease_prodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004236">
        <property type="entry name" value="Pept_S1_alpha_lytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001316">
        <property type="entry name" value="Pept_S1A_streptogrisin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035070">
        <property type="entry name" value="Streptogrisin_prodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001254">
        <property type="entry name" value="Trypsin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018114">
        <property type="entry name" value="TRYPSIN_HIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033116">
        <property type="entry name" value="TRYPSIN_SER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02983">
        <property type="entry name" value="Pro_Al_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00089">
        <property type="entry name" value="Trypsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001134">
        <property type="entry name" value="Streptogrisin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00861">
        <property type="entry name" value="ALYTICPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54806">
        <property type="entry name" value="SSF54806"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00134">
        <property type="entry name" value="TRYPSIN_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00135">
        <property type="entry name" value="TRYPSIN_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594759" evidence="7">
        <location>
            <begin position="33"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="Pro_Al_protease" evidence="9">
        <location>
            <begin position="119"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S1" evidence="8">
        <location>
            <begin position="233"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="269"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="5">
        <location>
            <position position="350"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="308"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="344"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001134-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001134-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN57088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="406" mass="41835" checksum="01D95AFAFA606099" modified="2016-02-17" version="1">MTVSQSVRRPVGRSLLLALASTAAFASVQAVAAEPIDPRLQQAMQRDLGVSAERLPQYLATQRLSLQQGAAAQRALGSTFAGSWIERKADGSFGFVVATSGTGKAARSLGGVEVRNVRHSLLQLERSFAALDAQSNARVPGISRAFEGVQSWRVDPVSNAVVVTVAPGAIGEGVELVALSGADAGAVRFETGEGSPQLTAEVVGGIEYSWPVGSQFGVCSVGFPATKGSVRGFVTAGHCGTVGKNVNVGNRASLIPLGTFANSDFPGTDMAWVTINANHTLSGRVSNYSGGFVSVKGSVEAPIGAALCRSGRTTFYKCGTIRSKNVTVNYREGTVRGLTESNVCTGGGDSGGSWITADGQAQGVTSGGQIPLGAPDNCSVAASSRVTWFQPLKPILSKYGVTLVTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFV6</accession>
    <name>A0A0S2DFV6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Oxidoreductase, 2OG-Fe(II) oxygenase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_1894</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1894"/>
    <dbReference type="EnsemblBacteria" id="ALN57245">
        <property type="protein sequence ID" value="ALN57245"/>
        <property type="gene ID" value="GLE_1894"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1894"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1862"/>
    <dbReference type="OMA" id="HNDSLTW"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="P4HA-like"/>
    </dbReference>
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        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PTHR10869"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="P4Hc" evidence="4">
        <location>
            <begin position="8"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="182" mass="19953" checksum="3FD24A0CE543A999" modified="2016-02-17" version="1">MQTIHHTETVFTVAGLLSPAECEALIALAEARGFEPAGVRTADGGQKAMAHVRNNERAVFESPHWTDTLWQRLRGAGLPALDGETACGLPRALRFYKYGPGQRFRMHKDGPWSEDGRLSKLTLLVYLNDGFVGGDTAFRGFRVAPRAGDALLFVHDTWHEGAAVEQGTKYALRSDVMYAPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFX0</accession>
    <name>A0A0S2DFX0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2100"/>
    <dbReference type="EnsemblBacteria" id="ALN57450">
        <property type="protein sequence ID" value="ALN57450"/>
        <property type="gene ID" value="GLE_2100"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2100"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2064"/>
    <dbReference type="OMA" id="SVRMMRA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="13"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="357" mass="38518" checksum="CBCA5757CD6DA5D6" modified="2016-02-17" version="1">MSAPATSPAGMKVLVTGANGFVGLNIVEQAIRAGHRPVAYVREGSNVAHLAPMGVEIVRGELSDEAALTAALRGAGGVVHTAGNTSCNRRDWPALEAVNVHGTRTVVRAALAAGVPRLVYTSTTSTVGAVDDPARRSDENRPLRGFRSRSPYAQSKFLGEEAVLDGARQGLHCVILNPAEVIGAYDHNLQWGRMLLAVQHNQVPFLPPGGGSFCHAADVGRAHVAALSQGRSGERYLLAGHDVRYVDFLDAIGEVLGKDFDRPGGDYQRLYYKTLLQEKHPHLLPGEPIVEAYRMRVFAGSYYFDSAKAERELSYRSAPLAHMLRDCADWYRRHGYFGPQAQAEAEAQAPAEDAALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFY3</accession>
    <name>A0A0S2DFY3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transporter, major facilitator family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_2076</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57426">
        <property type="protein sequence ID" value="ALN57426"/>
        <property type="gene ID" value="GLE_2076"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2076"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2041"/>
    <dbReference type="OMA" id="MWGIATL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="275"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="299"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="366"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="397"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="426"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="468"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="492"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="84"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN57426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="519" mass="52596" checksum="11F62DFB07AD333D" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG14</accession>
    <name>A0A0S2DG14_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4189 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2058</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947248.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2058"/>
    <dbReference type="EnsemblBacteria" id="ALN57408">
        <property type="protein sequence ID" value="ALN57408"/>
        <property type="gene ID" value="GLE_2058"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2058"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2023"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025240">
        <property type="entry name" value="DUF4189"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13827">
        <property type="entry name" value="DUF4189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4189" evidence="1">
        <location>
            <begin position="24"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="124" mass="13847" checksum="46CC6EEFF2C027DB" modified="2016-02-17" version="1">MQRGNGWQGCAERPEAATVYYDRWGAIATDESNGAFGAAEWFARKDNAERKALKECRKNRGIDCAIKFTYTNECVSVITGARMNYFQSSVSDQAAISHGLRRCQKDDSDCKVFYVGCSLPRKGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG21</accession>
    <name>A0A0S2DG21_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57424">
        <property type="protein sequence ID" value="ALN57424"/>
        <property type="gene ID" value="GLE_2074"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2074"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2039"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="94" mass="9865" checksum="D4B02A09D45D3CD5" modified="2016-02-17" version="1">MAHRRGGRDGGPWSGPPAACASSAVRAARSRSASCFLRDGLHSLCGRGLMSLWEGLPLRHRAFLEARPPPARPPYAAAGSRRAGRGHKSVIGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG50</accession>
    <name>A0A0S2DG50_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">3-hydroxyacyl-coa dehydrogenase type II</fullName>
            <ecNumber evidence="1">1.1.1.178</ecNumber>
            <ecNumber evidence="1">1.1.1.35</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="2">SDR family NAD(P)-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_09815</name>
        <name evidence="1" type="ORF">GLE_1928</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.178" evidence="1"/>
    <dbReference type="EC" id="1.1.1.35" evidence="1"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947149.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1928"/>
    <dbReference type="EnsemblBacteria" id="ALN57279">
        <property type="protein sequence ID" value="ALN57279"/>
        <property type="gene ID" value="GLE_1928"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1928"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1894"/>
    <dbReference type="OMA" id="QGIRVCT"/>
    <dbReference type="OrthoDB" id="1260864at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047015">
        <property type="term" value="F:3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003857">
        <property type="term" value="F:3-hydroxyacyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="256" mass="26428" checksum="4AFD8E1C611A10D7" modified="2016-02-17" version="1">MQLENARAAITGGVSGLGFAVAQHLVARGGKVALFDVNDDKGAQAVAALGEGNARYFRTDVTDEAGVSANLKAAKEFLGGLNAAINCAGILGAGRVLGKEAPMALSQFQTTVMVNLVGSFNVAKAAADLMQHNEPGADGERGVIVNTASVAAYEGQIGQAAYSASKGGVVGMTLPMARELARFGIRVMTVAPGIFWTPMVDGMPESVQQSLSASIPFPSRLGKPEEFADLVAYILGNTYLNGETIRLDGATRLAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGD7</accession>
    <name>A0A0S2DGD7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">High frequency lysogenization protein HflD homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1 3" type="primary">hflD</name>
        <name evidence="3" type="ORF">FE772_11555</name>
        <name evidence="2" type="ORF">GLE_2300</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the HflD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947433.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2300"/>
    <dbReference type="EnsemblBacteria" id="ALN57649">
        <property type="protein sequence ID" value="ALN57649"/>
        <property type="gene ID" value="GLE_2300"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2300"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2265"/>
    <dbReference type="OMA" id="RYIISLM"/>
    <dbReference type="OrthoDB" id="870739at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3890.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00695">
        <property type="entry name" value="HflD_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007451">
        <property type="entry name" value="HflD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035932">
        <property type="entry name" value="HflD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38100">
        <property type="entry name" value="PTHR38100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04356">
        <property type="entry name" value="DUF489"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101322">
        <property type="entry name" value="SSF101322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="202" mass="21871" checksum="E5A9A05C32783224" modified="2016-02-17" version="1">MAELSERVLALAGLAQALAQVRRIADTGQANASVLETALESVFRIDASSPTAVYGSVAQLRPGLVLVQDYFTSRSHDEHLPRLALAVLQLERRFVQDAAMADQVLGGIRAQADQAQRLGSSHPDVIAALGTLYADTLSHLRPRVLVQGNPHYLGQPGVVAEVRAVLLAAVRSAVLWRQLGGSYWDFLLRKRAMVDATEARLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGS1</accession>
    <name>A0A0S2DGS1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2422</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2422"/>
    <dbReference type="EnsemblBacteria" id="ALN57771">
        <property type="protein sequence ID" value="ALN57771"/>
        <property type="gene ID" value="GLE_2422"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2422"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2384"/>
    <dbReference type="OMA" id="KPWVEAN"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595547" evidence="2">
        <location>
            <begin position="37"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="362" mass="38886" checksum="764C02A4307B6090" modified="2016-02-17" version="1">MPSLEPTRVFRLLARLRLLAGTAALALCLAASPALAQPDPNQRIGQTVADAASPHYRFERFVVADGERRWRIHLAIPRQRAGRDGYAALYMLDGNAALMEFDAPLLDRLARGRAPVLAFVGYDNELRIDGAARTRDYTPSAVDDGLGQGPRGGGAAAFAAALAERIQPEVRRRARIDRSREALWGHSLGGLFVLDLLYTRADAFAQWFPASPSLWWDNGRELGAPERQFLQGELRRPAGVAIMQGGSERAPNRGPGDAARSDDPRVAAHRARIAAVPADAAQQLAQRLQAKPGLRACYREFAGLGHGPMLRASVRAAALAMAGDPARACADAQGPSSRDSSSRDPAREASESARAATSPVEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGS4</accession>
    <name>A0A0S2DGS4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF412 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_12630</name>
        <name evidence="2" type="ORF">GLE_2513</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2513"/>
    <dbReference type="EnsemblBacteria" id="ALN57862">
        <property type="protein sequence ID" value="ALN57862"/>
        <property type="gene ID" value="GLE_2513"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2513"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2476"/>
    <dbReference type="OMA" id="ELMIHAM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="524"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="549"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="645"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="670"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="706" mass="77840" checksum="2E37DD6B263A37E4" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGT6</accession>
    <name>A0A0S2DGT6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein-glutamate methylesterase/protein-glutamine glutaminase</fullName>
            <ecNumber evidence="4">3.1.1.61</ecNumber>
            <ecNumber evidence="4">3.5.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 9" type="primary">cheB</name>
        <name evidence="9" type="ORF">GLE_2448</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>H2O + L-glutaminyl-[protein] = L-glutamyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16441"/>
            <dbReference type="Rhea" id="RHEA-COMP:10207"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="EC" id="3.5.1.44"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[protein]-L-glutamate 5-O-methyl ester + H2O = H(+) + L-glutamyl-[protein] + methanol</text>
            <dbReference type="Rhea" id="RHEA:23236"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="Rhea" id="RHEA-COMP:10311"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:82795"/>
            <dbReference type="EC" id="3.1.1.61"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="4">Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.</text>
    </comment>
    <comment type="PTM">
        <text evidence="4">Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CheB family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.61" evidence="4"/>
    <dbReference type="EC" id="3.5.1.44" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947545.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2448"/>
    <dbReference type="EnsemblBacteria" id="ALN57797">
        <property type="protein sequence ID" value="ALN57797"/>
        <property type="gene ID" value="GLE_2448"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2448"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2411"/>
    <dbReference type="OMA" id="QHINAAF"/>
    <dbReference type="OrthoDB" id="1655418at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008984">
        <property type="term" value="F:protein-glutamate methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050568">
        <property type="term" value="F:protein-glutamine glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018277">
        <property type="term" value="P:protein deamination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006482">
        <property type="term" value="P:protein demethylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16432">
        <property type="entry name" value="CheB_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00099">
        <property type="entry name" value="CheB_chemtxs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008248">
        <property type="entry name" value="CheB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035909">
        <property type="entry name" value="CheB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000673">
        <property type="entry name" value="Sig_transdc_resp-reg_Me-estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01339">
        <property type="entry name" value="CheB_methylest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000876">
        <property type="entry name" value="RR_chemtxs_CheB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52738">
        <property type="entry name" value="SSF52738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50122">
        <property type="entry name" value="CHEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 5" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="2"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="CheB-type methylesterase" evidence="8">
        <location>
            <begin position="141"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="275"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4 6">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN57797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="338" mass="35433" checksum="E0A678C6576118CD" modified="2016-02-17" version="1">MRIGIVNDLGIATEALRRVLARRADFRVAWAAASGEDAVAHCARDTPDLVLMDLVMPGMNGVEATRRIMAASPCPILVVTVSVGANAAMVFEAMGHGALDATDMPSLGGEENGGADKLLAKIDLIGRLTAAPPRPLPARAPASGAAHPLLAIGASAGGPSAVARLLEGLPADFAGAVAVIQHIDEKFAPGMADWLGRYSRLPVRIANTGDTLQPGRVLLAATNDHLSLRADARLDYVREPAQLPYRPSVDVFYKSVAEHWRGPIVGVLLTGMGRDGAAGLRLLRDQGHHTIAQDRATSAVYGMPKAAAELDAAVEILPLDRIAARVRDLFAQTQTASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGW1</accession>
    <name>A0A0S2DGW1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type II toxin-antitoxin system VapC family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_11540</name>
        <name evidence="2" type="ORF">GLE_2297</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947430.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2297"/>
    <dbReference type="EnsemblBacteria" id="ALN57646">
        <property type="protein sequence ID" value="ALN57646"/>
        <property type="gene ID" value="GLE_2297"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2297"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2262"/>
    <dbReference type="OMA" id="GEMHRRH"/>
    <dbReference type="OrthoDB" id="1968541at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="132" mass="14250" checksum="0A82F90A789BAB62" modified="2016-02-17" version="1">MIAVDSPVLIELLSDGPQADAVESCLRQSLVGGRVVVCDVSLAEICAALRGGAQAQEALEEMGIHFSALEAKSALRAGEMHRRHRQRGGEPRGFGGFLVGAHALLQCDGLITWNDMFYRDYFKGLKLIVPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH62</accession>
    <name>A0A0S2DH62_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4287 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_11975</name>
        <name evidence="2" type="ORF">GLE_2392</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947506.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2392"/>
    <dbReference type="EnsemblBacteria" id="ALN57741">
        <property type="protein sequence ID" value="ALN57741"/>
        <property type="gene ID" value="GLE_2392"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2392"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2354"/>
    <dbReference type="OrthoDB" id="1973287at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025629">
        <property type="entry name" value="DUF4287"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14117">
        <property type="entry name" value="DUF4287"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="164" mass="16134" checksum="6EAB07E1A8C99737" modified="2016-02-17" version="1">MAIASRSKTPVAKTAVKNSAAAKAVAKKAPGNAGTAGKTAAAGKPAVAKPAASKPIASKPAAAKSTAAKPAAVKKPAAAAKPAAAKKPAAQAPAAADKVKGPASYFPSIEKTYGKPVAHWFAAIDALGARKHMELVAELKRAHGLGHGHANALVAYRLAQAGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHH9</accession>
    <name>A0A0S2DHH9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2727</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58075">
        <property type="protein sequence ID" value="ALN58075"/>
        <property type="gene ID" value="GLE_2727"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2727"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2685"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="53" mass="6029" checksum="B1B85FA8BBC012AC" modified="2016-02-17" version="1">MIWLLFPLRHEQERRQESKWIPAFAGMTGAGLARPEKPINAFIGRIGIPASRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHK6</accession>
    <name>A0A0S2DHK6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_23835</name>
        <name evidence="2" type="ORF">GLE_2712</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000086">
        <property type="protein sequence ID" value="OPD61423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947758.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000086.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58060">
        <property type="protein sequence ID" value="ALN58060"/>
        <property type="gene ID" value="GLE_2712"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61423">
        <property type="protein sequence ID" value="OPD61423"/>
        <property type="gene ID" value="BV903_23835"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2712"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2671"/>
    <dbReference type="OMA" id="YATMDQS"/>
    <dbReference type="OrthoDB" id="1674118at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595148" evidence="1">
        <location>
            <begin position="24"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="181" mass="18506" checksum="038F140CED0DBDB4" modified="2016-02-17" version="1">MTARTVPVAALLAAALAAAFAGACSRQPDGGVQVSVIDHISMDGDKVLLRAAGRSAQIGPDGAIAIDGGALALTPAQQALGREFYQQATGMRRDGAAMGKAGAAMAGHALSTVARDLRDGNTDQTEAKIQAEAAKLEAQALQLCQRAQALRDAQQRLSAALPQFEPFAGLAAGIGDDCRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHS9</accession>
    <name>A0A0S2DHS9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2742</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58090">
        <property type="protein sequence ID" value="ALN58090"/>
        <property type="gene ID" value="GLE_2742"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2742"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2700"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="46" mass="5047" checksum="254D0EED95155EC2" modified="2016-02-17" version="1">MDGGRVRGRLSLLVHPLPRSPRRRARTSCPGCARVAGLRCGYRVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHV0</accession>
    <name>A0A0S2DHV0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2882</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58230">
        <property type="protein sequence ID" value="ALN58230"/>
        <property type="gene ID" value="GLE_2882"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2882"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="46" mass="5160" checksum="92449B2BE3FD5183" modified="2016-02-17" version="1">MKKHRIIPLERVDEMRFGPQPRDCAGDAAGRSLPDARIGGRTTARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHV9</accession>
    <name>A0A0S2DHV9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-alanine synthetase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Carbon-nitrogen hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_14620</name>
        <name evidence="2" type="ORF">GLE_2931</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947920.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2931"/>
    <dbReference type="EnsemblBacteria" id="ALN58279">
        <property type="protein sequence ID" value="ALN58279"/>
        <property type="gene ID" value="GLE_2931"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2931"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2893"/>
    <dbReference type="OMA" id="NAPYFCQ"/>
    <dbReference type="OrthoDB" id="1583074at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="301" mass="33598" checksum="D748906AFC1C0738" modified="2016-02-17" version="1">MKKNTLPVALIQDRDHGSREANLANIEQRVGEAARQGAKLVLLQELHNGPYFCQHESVQEFDLAEPIPGPSTERLGALAKQHGIVLVSSLFERRAPGLYHNTAVVYETDGAIAGKYRKMHIPDDPGFYEKFYFTPGDIGFEPIQTSVGRLGVLVCWDQWYPEGARLMALAGAELLLYPTAIGWDPSDAQDEKDRQRNAWILSHRGHAVANGLPVLSVNRVGFEPSPMASENTAGASGIQFWGSSHVLGPQGEYLAEAKTAEPEIVMAEVDLQRSEHVRRIWPFLRDRRIDAYADLLKRYRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI15</accession>
    <name>A0A0S2DI15_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminotransferase class I and II</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Pyridoxal phosphate-dependent aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_14105</name>
        <name evidence="2" type="ORF">GLE_2824</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947841.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2824"/>
    <dbReference type="EnsemblBacteria" id="ALN58172">
        <property type="protein sequence ID" value="ALN58172"/>
        <property type="gene ID" value="GLE_2824"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2824"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2782"/>
    <dbReference type="OMA" id="SQGANQY"/>
    <dbReference type="OrthoDB" id="1462898at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="28"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="382" mass="42211" checksum="A48AEE2DA44232F6" modified="2016-02-17" version="1">MTLATKLPKVGTTIFTVMSQLALEHQAVNLGQGFPDFDVPQRLVDALARAMAEGKNQYAPMTGVPALRQAIADKTEACYGYRPDADAEITVVSGASEAIFDAVQAVVRPGEEVVVLDPCYDSYEPAIDLAGGRAVHVPLDPVTFAVDWDRVRAAIGPNTRLLMVNSPHNPSGAMFDADDIARLSDIVESTGVWLLSDEVYEHIVFDGRRHESVLRYPQLRERAFVVSSFGKTYHCTGWKIGYCIAPPALSAELRKVHQYNSFCSFAPAQWAFAEMIRDEPEHYRQLGAFYQDKRDGFREQLSTTRLKPLPVPGGYFQLVDYSAVSDLDDAAFCRWLTMEKGVAAIPLSPFYESPPAGQRLARLCFAKNQATLDAAIKRLVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIK3</accession>
    <name>A0A0S2DIK3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytidylate kinase</fullName>
            <shortName evidence="8">CK</shortName>
            <ecNumber evidence="8">2.7.4.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cytidine monophosphate kinase</fullName>
            <shortName evidence="8">CMP kinase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">cmk</name>
        <name evidence="11" type="ORF">FE772_14595</name>
        <name evidence="10" type="ORF">GLE_2926</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + CMP = ADP + CDP</text>
            <dbReference type="Rhea" id="RHEA:11600"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58069"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>ATP + dCMP = ADP + dCDP</text>
            <dbReference type="Rhea" id="RHEA:25094"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57566"/>
            <dbReference type="ChEBI" id="CHEBI:58593"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the cytidylate kinase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.25" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947917.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2926"/>
    <dbReference type="EnsemblBacteria" id="ALN58274">
        <property type="protein sequence ID" value="ALN58274"/>
        <property type="gene ID" value="GLE_2926"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2926"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2888"/>
    <dbReference type="OMA" id="RAITWWM"/>
    <dbReference type="OrthoDB" id="776861at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004127">
        <property type="term" value="F:cytidylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006220">
        <property type="term" value="P:pyrimidine nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02020">
        <property type="entry name" value="CMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00238">
        <property type="entry name" value="Cytidyl_kinase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003136">
        <property type="entry name" value="Cytidylate_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011994">
        <property type="entry name" value="Cytidylate_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02224">
        <property type="entry name" value="Cytidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00017">
        <property type="entry name" value="cmk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cytidylate_kin" evidence="9">
        <location>
            <begin position="15"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="18"/>
            <end position="26"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN58274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW28765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="230" mass="24583" checksum="7765E97998D81F5E" modified="2016-02-17" version="1">MNSASSQNPHVPVLTIDGPSGSGKGTISRLVAQRLGWHYLDSGALYRAVGVAAGWADLDLADPAALVRCAFDTHIGFRDDASGELRVLVNDVDATDELRTETAGAAASAIAAIPEVRAALKDRQRAFRQEPGLVADGRDMGTVIFPDAQYKVFLTASAEERAERRYKQLKDKGVSVTLDGLLREILARDARDAQRAVAPLRPADDAVRIDTTGLGIDTVVEQVLALLPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIK4</accession>
    <name>A0A0S2DIK4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA-binding response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Transcriptional regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BV903_02945</name>
        <name evidence="9" type="ORF">D9T17_16880</name>
        <name evidence="8" type="ORF">FE772_14860</name>
        <name evidence="6" type="ORF">GLE_2972</name>
    </gene>
    <organism evidence="6 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 10">C3</strain>
        </source>
    </reference>
    <reference evidence="7 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">OH11</strain>
        </source>
    </reference>
    <reference evidence="8 13" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 13">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000005">
        <property type="protein sequence ID" value="OPD65491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000041">
        <property type="protein sequence ID" value="ROU05850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947949.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2972"/>
    <dbReference type="EnsemblBacteria" id="ALN58320">
        <property type="protein sequence ID" value="ALN58320"/>
        <property type="gene ID" value="GLE_2972"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65491">
        <property type="protein sequence ID" value="OPD65491"/>
        <property type="gene ID" value="BV903_02945"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2972"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2933"/>
    <dbReference type="OMA" id="FIDHPQR"/>
    <dbReference type="OrthoDB" id="817710at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
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        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="6"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="137"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="137"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD65491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW26735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROU05850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="246" mass="27756" checksum="4980DF68D9E186B9" modified="2016-02-17" version="1">MKPSDHILIVDDDRDIRDMVADYLRKNGLRASTAADGREMRAALEAQDIDLIVLDLMLPGDDGLVLCRNLRAGPHKAIPVLMLTARDDATDRIVGLEMGADDYLAKPFAPRELLARINAVIRRTRMLPPNLRVSEATRLIAFGHWRLDTTARHLLDRDGTAIALSGAEFRLLRVFLDHPQRVLSRDQLLNLTQGRDAEHFDRSIDLLVSRLRQRLQDDARDQSYIKTVRSEGYVFSQAVTLVGEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIP2</accession>
    <name>A0A0S2DIP2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glucose-6-phosphate isomerase</fullName>
            <shortName evidence="7">GPI</shortName>
            <ecNumber evidence="7">5.3.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Phosphoglucose isomerase</fullName>
            <shortName evidence="7">PGI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Phosphohexose isomerase</fullName>
            <shortName evidence="7">PHI</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">pgi</name>
        <name evidence="10" type="ORF">FE772_15765</name>
        <name evidence="9" type="ORF">GLE_3172</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7 8">
            <text>alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11816"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="EC" id="5.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 7 8">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the GPI family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.9" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948095.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3172"/>
    <dbReference type="EnsemblBacteria" id="ALN58518">
        <property type="protein sequence ID" value="ALN58518"/>
        <property type="gene ID" value="GLE_3172"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3172"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3127"/>
    <dbReference type="OMA" id="CPAYAYG"/>
    <dbReference type="OrthoDB" id="417261at2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00181"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05015">
        <property type="entry name" value="SIS_PGI_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05016">
        <property type="entry name" value="SIS_PGI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00473">
        <property type="entry name" value="G6P_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023096">
        <property type="entry name" value="G6P_Isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018189">
        <property type="entry name" value="Phosphoglucose_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035476">
        <property type="entry name" value="SIS_PGI_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035482">
        <property type="entry name" value="SIS_PGI_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469">
        <property type="entry name" value="PTHR11469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00342">
        <property type="entry name" value="PGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00662">
        <property type="entry name" value="G6PISOMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00765">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 8" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="4 7 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="338"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="369"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN58518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW26881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="508" mass="54632" checksum="22E865F09D855A74" modified="2016-02-17" version="1">MSDASRLNELRAEVGRVAATPLSRLVSADPARAGDFALKVGPVYANFARQYYDRDAVRWLFRAAEAAGSAQRVRALFDGETVNVTEGRPALHTALRGDFSHAPVAHEAHREALKARARMRATIEALEASEVTDIVSVGIGGSDLGPRLAVDALSGPKPGRFRVHFLSNVDGHAAQRTLAGLDPKRTAALLISKTFGTQETLLNGGILRDWLGDSAGLDGGRLYAISANLERPAQAFDIPPERILPMWDWVGGRYSLWSAVGLPIALAIGMDGFEQFLSGAAQMDAHVLQTPLEGNLAAWHALTSIWNRNGLGYAAQAVLAYDERLKLLSNYLQQLVMESLGKSVKLDGSPVGEDTVPVWWGGAGTDTQHSFFQALHQGTSIVPADFIGVVRSDAPYPQNHRALHANLLAQTEAFANGQRSDDPHRAYAGGRPSTTILLDALTPASLGALLAMYEHSVYLQSVFWGINAFDQFGVELGKQVASKLLPALAGEAQAEDPVTRELLARLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIS9</accession>
    <name>A0A0S2DIS9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF4189 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_14035</name>
        <name evidence="3" type="ORF">GLE_2811</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947830.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58159">
        <property type="protein sequence ID" value="ALN58159"/>
        <property type="gene ID" value="GLE_2811"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2811"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2768"/>
    <dbReference type="OMA" id="ANEECRR"/>
    <dbReference type="OrthoDB" id="2032402at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025240">
        <property type="entry name" value="DUF4189"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13827">
        <property type="entry name" value="DUF4189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726666" evidence="1">
        <location>
            <begin position="23"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4189" evidence="2">
        <location>
            <begin position="64"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="175" mass="18228" checksum="74EB38E19F7E7B1A" modified="2016-02-17" version="1">MQFRYVALAGVLLTGLCTHAKAEQGCPDGFTPNPAPTGTPGATQCIPIGSFGGSLEYSGWNNSYGAVFFDAEKGLVGIGEGQKNRRRARKEALQHCQSKGGTDCKEVLWYSNGCAAVVWGPSKSGQGFTMETRSQATLGAAVASAKQACAPNSASGECEVFYSGCSEPVPFSNTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIX0</accession>
    <name>A0A0S2DIX0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Acyl-CoA dehydrogenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Glutaryl-CoA dehydrogenase, (GCD)</fullName>
            <ecNumber evidence="9">1.3.8.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FE772_15270</name>
        <name evidence="9" type="ORF">GLE_3055</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.3.8.6" evidence="9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948009.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3055"/>
    <dbReference type="EnsemblBacteria" id="ALN58402">
        <property type="protein sequence ID" value="ALN58402"/>
        <property type="gene ID" value="GLE_3055"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3055"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3015"/>
    <dbReference type="OMA" id="AAMDCYD"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004361">
        <property type="term" value="F:glutaryl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="16"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="132"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="234"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN58402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW26800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="387" mass="42304" checksum="B215B5447AE509B5" modified="2016-02-17" version="1">MALHPYDLFDVRSLLSEEERAVQDTVARFTDERVIPIIGDAFDQGRFPKELVPEIAELGLLGSSLPEQYGCADLNAVSYGLICQELERGDSGIRSFVSVQSSLCMYPIYAYGSEEQRMRWLPGMAKGEIIGCFGLTEPHGGSDPANMKTNAKRDGGDWILNGSKMWITNGNLADIAIVWAQTEDGIQGFVVEKGMPGFAAQEIKHKMSLRASVTSSLFFDNVRVPDANRLPNVKGLKGPLGCLTQARYGITWGPIGAAIACLDEVLGYTKERILFNRPVAATQSAQIKMAEMARRITLAQLLVVQLGRLKDAGNMQPTQVSLAKWNNCRMAIDIARECRDLLGGAGITTEHGAIRHALNLESVITYEGTETVHQLVVGRELTGINAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIX1</accession>
    <name>A0A0S2DIX1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD dependent epimerase/dehydratase family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">NAD(P)-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_15060</name>
        <name evidence="2" type="ORF">GLE_3013</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947980.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3013"/>
    <dbReference type="EnsemblBacteria" id="ALN58361">
        <property type="protein sequence ID" value="ALN58361"/>
        <property type="gene ID" value="GLE_3013"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3013"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2974"/>
    <dbReference type="OMA" id="DRVYVNE"/>
    <dbReference type="OrthoDB" id="1180629at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="327" mass="36114" checksum="C5652C637F2110E7" modified="2016-02-17" version="1">MSVLVTGSAGHLGEGLMRLLRAQGRAARGIDLKPSAFTDFAGSIADPDFVAEAMHGVDAVIHAATLHKPHVATHRYQDFVDTNITGTLNLLQAAHERGVRSFVFTSTTSAFGAALTPAPGEPAAWIDEGVAPIPKNIYGTTKIAAEGLCELFHRRHRLPVLVLRTSRFFPEDDDDAARRAEYDTANSQANELLYRRADIDDVAQAHLCAIERAPALGFGRYIVSATTPFRREHLAELSVDAAAVVRRLFPRCGELYAAKGWNLFPRLDRVYVNDAARRDLGWEPRYGFDYVLDCLQRGLDFRSALAHEVGVKGYHAQRFEDMPYPVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ73</accession>
    <name>A0A0S2DJ73_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58514">
        <property type="protein sequence ID" value="ALN58514"/>
        <property type="gene ID" value="GLE_3168"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3168"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="64" mass="7211" checksum="FE1CBDD74838F2F4" modified="2016-02-17" version="1">MSEIPGQRCQERQAHQDFLNGGPLDSHGRKSSTEIVELQVFFPCKSGTCRYFLGNRSGVGRKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJC2</accession>
    <name>A0A0S2DJC2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58521">
        <property type="protein sequence ID" value="ALN58521"/>
        <property type="gene ID" value="GLE_3175"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3175"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3130"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="53" mass="5473" checksum="CBEE6A79C25D33F5" modified="2016-02-17" version="1">MERRRGSDGAIHARDGPDWLPDEREGTSGAAPRPMSGRAAAISSPAAAARAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJC4</accession>
    <name>A0A0S2DJC4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BV903_09150</name>
        <name evidence="9" type="ORF">FE772_16040</name>
        <name evidence="7" type="ORF">GLE_3232</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000020">
        <property type="protein sequence ID" value="OPD64209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948139.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000020.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3232"/>
    <dbReference type="EnsemblBacteria" id="ALN58578">
        <property type="protein sequence ID" value="ALN58578"/>
        <property type="gene ID" value="GLE_3232"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64209">
        <property type="protein sequence ID" value="OPD64209"/>
        <property type="gene ID" value="BV903_09150"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3232"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3185"/>
    <dbReference type="OMA" id="YAYGFIM"/>
    <dbReference type="OrthoDB" id="1445898at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD64209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW26921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="261" mass="26645" checksum="0BBFB43772843AE5" modified="2016-02-17" version="1">MEFGIEVIALLMAVAFVAGVIDALAGGGGLLTIPALMAAGIPPVAAIATNKLQSSFGTASAVYAFARKGRIDFRRFRKPALAAFAGSALGALTLQHVSPAFLSGLIPVLLIAMVVYFALAPKASEDDRHSRLGPAALVGLVAAIGFYDGFFGPGTGAFLTTALVALFGMGLVSATAHTKFLNLSSNVAALLALIVGGQVLWTLGLLMALSSVLGGQLGAHLALRVGARVIRPLLLVMSLLLTAKLLSDPANPLTRSVLGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJF1</accession>
    <name>A0A0S2DJF1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BV903_20420</name>
        <name evidence="10" type="ORF">FE772_16360</name>
        <name evidence="8" type="ORF">GLE_3308</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000062">
        <property type="protein sequence ID" value="OPD62051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948195.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000062.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3308"/>
    <dbReference type="EnsemblBacteria" id="ALN58654">
        <property type="protein sequence ID" value="ALN58654"/>
        <property type="gene ID" value="GLE_3308"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62051">
        <property type="protein sequence ID" value="OPD62051"/>
        <property type="gene ID" value="BV903_20420"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3308"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3258"/>
    <dbReference type="OrthoDB" id="1861282at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000774">
        <property type="entry name" value="PPIase_FKBP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036944">
        <property type="entry name" value="PPIase_FKBP_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01346">
        <property type="entry name" value="FKBP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0697">Rotamase</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595702" description="Peptidyl-prolyl cis-trans isomerase" evidence="6">
        <location>
            <begin position="23"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="7">
        <location>
            <begin position="142"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD62051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW26976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="228" mass="24255" checksum="7B2CA3BE83477765" modified="2016-02-17" version="1">MKLRLIAAAVAALALTAGNAVAQDTSSEKGKLSYALGYDLGRNAVESGEAVDVNTIVKGLQDGYAKKQPSVPVDQLRTAVQNMQKRQAEKAKAEWDKAAAENKTKSDTFVNANKAKAGVKVLPGGAQYRVVENGTGAKPTQASTVALEVAGPFPWGERPAQARPANNIPSIKVSEIEMQAMRDVLLQMPAGSKWEVTLPSEKAYGADPRTPFPPNVAVQFEIKLISVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJF8</accession>
    <name>A0A0S2DJF8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Probable nicotinate-nucleotide adenylyltransferase</fullName>
            <ecNumber evidence="7">2.7.7.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Deamido-NAD(+) diphosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Deamido-NAD(+) pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Nicotinate mononucleotide adenylyltransferase</fullName>
            <shortName evidence="7">NaMN adenylyltransferase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">nadD</name>
        <name evidence="10" type="ORF">BV903_18020</name>
        <name evidence="9" type="ORF">GLE_3434</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">B25</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + H(+) + nicotinate beta-D-ribonucleotide = deamido-NAD(+) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22860"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="EC" id="2.7.7.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Cofactor biosynthesis; NAD(+) biosynthesis; deamido-NAD(+) from nicotinate D-ribonucleotide: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the NadD family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.18" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000048">
        <property type="protein sequence ID" value="OPD62559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948291.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000048.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3434"/>
    <dbReference type="EnsemblBacteria" id="ALN58779">
        <property type="protein sequence ID" value="ALN58779"/>
        <property type="gene ID" value="GLE_3434"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62559">
        <property type="protein sequence ID" value="OPD62559"/>
        <property type="gene ID" value="BV903_18020"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3434"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3384"/>
    <dbReference type="OMA" id="IHIGHLI"/>
    <dbReference type="OrthoDB" id="1433958at2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00332"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004515">
        <property type="term" value="F:nicotinate-nucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02165">
        <property type="entry name" value="NMNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00244">
        <property type="entry name" value="NaMN_adenylyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005248">
        <property type="entry name" value="NadD/NMNAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00482">
        <property type="entry name" value="TIGR00482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="8">
        <location>
            <begin position="6"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN58779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD62559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="219" mass="23584" checksum="D01697E60FB90764" modified="2016-02-17" version="1">MSLAVFYGGTFDPIHDGHLAVARAARDALAAQVRLMPAADPPHRAAPGADARQRAHMLDLAVAGETGLVVDRRELQREGRSYTVETLREARAEFGPERPLALLVGADSFLDLPKWREWQALFGLAHFVVAERPGSPLDAARIEAIAPGRETADPAGLRQAPAGRVYRLKQPLHAESASQVREFIAAGRPWDEFVPPAVAAYIRECGLYGVVAGRGATPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJL1</accession>
    <name>A0A0S2DJL1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_16190</name>
        <name evidence="2" type="ORF">GLE_3271</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948167.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58617">
        <property type="protein sequence ID" value="ALN58617"/>
        <property type="gene ID" value="GLE_3271"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3271"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3224"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242202" evidence="1">
        <location>
            <begin position="29"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="70" mass="7470" checksum="64A7A4E8253DF823" modified="2016-02-17" version="1">MLQRTRNRLALLAAVAAFGFGLTFSVTAAPETCEQCLARCDQMRANCTTAACVHEAKMCAIRGCRSACSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJM4</accession>
    <name>A0A0S2DJM4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase RavA</fullName>
            <ecNumber evidence="2">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ravA</name>
        <name evidence="2" type="ORF">GLE_3492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.6.3.-" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948330.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3492"/>
    <dbReference type="EnsemblBacteria" id="ALN58837">
        <property type="protein sequence ID" value="ALN58837"/>
        <property type="gene ID" value="GLE_3492"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3492"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3437"/>
    <dbReference type="OMA" id="TRFTEPD"/>
    <dbReference type="OrthoDB" id="895310at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045427">
        <property type="entry name" value="MoxR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041538">
        <property type="entry name" value="RavA-like_AAA_lid"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17868">
        <property type="entry name" value="AAA_lid_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20030">
        <property type="entry name" value="bpMoxR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="44"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="380" mass="40464" checksum="AEE23532BA95173A" modified="2016-02-17" version="1">MISSPQDSAAQHAAARVRDAVHAATTGLIEREQLAELIVLAAVAQEHLLILGPPGTAKSAVVRRVAAALGGRYFEYLLGRFTEPSELFGPVDLRRLREGVVETDVSGMLPQAEVAFLDEVFLGSTAILNTLLGVLNERRFRRGHTQIACPLRVCVGASNALPDDESLAAFADRFLLHLFVEPVPDHQLEALLAGGWQAERLALSHQAELSDIDELSRRVPAVAMERARGALADAIRKLRGAGLSLSDRRIVKAQRLIAAAAVLAGRDHATEADLWPLFYVLPTREAQVAAQDVLRDSLAAAANPTLRAAVEHAALQPVSRVARLLEAARACLAGPGDAPGAGVIAEALLREIDANFDVDALPAELAAERARLAERVSAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJN9</accession>
    <name>A0A0S2DJN9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Inositol-1-monophosphatase</fullName>
            <ecNumber evidence="7">3.1.3.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">suhB</name>
        <name evidence="9" type="ORF">BV903_21555</name>
        <name evidence="11" type="ORF">D9T17_10605</name>
        <name evidence="10" type="ORF">FE772_17270</name>
        <name evidence="8" type="ORF">GLE_3508</name>
    </gene>
    <organism evidence="8 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 12">C3</strain>
        </source>
    </reference>
    <reference evidence="9 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">OH11</strain>
        </source>
    </reference>
    <reference evidence="10 15" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 15">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>a myo-inositol phosphate + H2O = myo-inositol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:24056"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:84139"/>
            <dbReference type="EC" id="3.1.3.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.25" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000071">
        <property type="protein sequence ID" value="OPD61865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000024">
        <property type="protein sequence ID" value="ROU06966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948341.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3508"/>
    <dbReference type="EnsemblBacteria" id="ALN58853">
        <property type="protein sequence ID" value="ALN58853"/>
        <property type="gene ID" value="GLE_3508"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61865">
        <property type="protein sequence ID" value="OPD61865"/>
        <property type="gene ID" value="BV903_21555"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3508"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3452"/>
    <dbReference type="OMA" id="RVDGYWE"/>
    <dbReference type="OrthoDB" id="1741160at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008934">
        <property type="term" value="F:inositol monophosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052832">
        <property type="term" value="F:inositol monophosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052833">
        <property type="term" value="F:inositol monophosphate 4-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01639">
        <property type="entry name" value="IMPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033942">
        <property type="entry name" value="IMPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022337">
        <property type="entry name" value="Inositol_monophosphatase_SuhB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01959">
        <property type="entry name" value="SBIMPHPHTASE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD61865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROU06966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="272" mass="29728" checksum="09D34B4002AC2E2C" modified="2016-02-17" version="1">MQKPAVTLMVKAARAAGNILLRHMHRLDALNVVEKDRMDYASEVDRLAEAEIIKEFRRATPDYAILGEEHGPLGQSRNTWVIDPLDGTSNYLHGIPHFCVSIALCENGEPTHGVIFDPLRNDLFTASRGSGMQLNEKRVRIADRKDLGGAMLITGFPPRERARASAHLKCLDNLLLDAEDVRRTGSAALDLAYVACGRADAYFEAGLKPWDVAAGVLMVREAGGKVSDFKGRATGPMDNRGLPPRQIVAGNLRIAEALQQRIVNTGYAAAFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJV1</accession>
    <name>A0A0S2DJV1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RHS repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_17085</name>
        <name evidence="1" type="ORF">GLE_3467</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948313.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3467"/>
    <dbReference type="EnsemblBacteria" id="ALN58812">
        <property type="protein sequence ID" value="ALN58812"/>
        <property type="gene ID" value="GLE_3467"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3467"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3414"/>
    <dbReference type="OMA" id="LTHEYDS"/>
    <dbReference type="OrthoDB" id="2288at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031325">
        <property type="entry name" value="RHS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006530">
        <property type="entry name" value="YD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05593">
        <property type="entry name" value="RHS_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01643">
        <property type="entry name" value="YD_repeat_2x"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="977" mass="106422" checksum="81FFF743202E65A5" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJV8</accession>
    <name>A0A0S2DJV8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3469</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58814">
        <property type="protein sequence ID" value="ALN58814"/>
        <property type="gene ID" value="GLE_3469"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3469"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3416"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="40" mass="3915" checksum="5DA50BC07E606C38" modified="2016-02-17" version="1">MREPGAGTRDQGPGTRDQGFEPFGPGSPVPGPGSTAMSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKB1</accession>
    <name>A0A0S2DKB1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase S9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3639"/>
    <dbReference type="EnsemblBacteria" id="ALN58983">
        <property type="protein sequence ID" value="ALN58983"/>
        <property type="gene ID" value="GLE_3639"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3639"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3583"/>
    <dbReference type="OMA" id="NPGDYYL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9" evidence="1">
        <location>
            <begin position="432"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="661" mass="71631" checksum="A4E6690459B6C188" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKI8</accession>
    <name>A0A0S2DKI8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 13">Glutamyl-tRNA reductase</fullName>
            <shortName evidence="8">GluTR</shortName>
            <ecNumber evidence="4 8 13">1.2.1.70</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 18" type="primary">hemA</name>
        <name evidence="18" type="ORF">GLE_3814</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 13">
            <text>(S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) = H(+) + L-glutamyl-tRNA(Glu) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:12344"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57501"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="EC" id="1.2.1.70"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8 13">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 13">Belongs to the glutamyl-tRNA reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.70" evidence="4 8 13"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3814"/>
    <dbReference type="EnsemblBacteria" id="ALN59157">
        <property type="protein sequence ID" value="ALN59157"/>
        <property type="gene ID" value="GLE_3814"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3814"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3756"/>
    <dbReference type="OMA" id="FAFKCAA"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00316"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008883">
        <property type="term" value="F:glutamyl-tRNA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00087">
        <property type="entry name" value="Glu_tRNA_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="4pyrrol_synth_GluRdtase"/>
    </dbReference>
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        <property type="entry name" value="GluRdtase_CS"/>
    </dbReference>
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        <property type="entry name" value="GluRdtase_dimer_dom_sf"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF00745">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05201">
        <property type="entry name" value="GlutR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01488">
        <property type="entry name" value="Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000445">
        <property type="entry name" value="4pyrrol_synth_GluRdtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF69075"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF69742"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01035">
        <property type="entry name" value="hemA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00747">
        <property type="entry name" value="GLUTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 11" id="KW-0521">NADP</keyword>
    <keyword evidence="6 8 13" id="KW-0560">Oxidoreductase</keyword>
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    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GlutR_N" evidence="17">
        <location>
            <begin position="16"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Shikimate_DH" evidence="16">
        <location>
            <begin position="178"/>
            <end position="311"/>
        </location>
    </feature>
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        <location>
            <begin position="326"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="59"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="120"/>
            <end position="122"/>
        </location>
    </feature>
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        <location>
            <begin position="422"/>
            <end position="450"/>
        </location>
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        <location>
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        </location>
    </feature>
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            <position position="115"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
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    <feature type="binding site" evidence="8 10">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <begin position="195"/>
            <end position="200"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for activity" evidence="8 12">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
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        </source>
    </evidence>
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    </evidence>
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    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00745"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF01488"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF05201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="ALN59157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="450" mass="48198" checksum="B9D05A658F1736BD" modified="2016-02-17" version="1">MRPGSATPPSMSLFVLGLNHQTAPVSLRERVAFAGDAVPAALASLRALAPVREVALLSTCNRTEIYAVAEDDGRALADWLARHPDDAGDLHGYLYRHRDAEAVRHLFRVATGLDSLVLGEPQILGQVKDAWAAARGAGTLGGQLDRLFQQAFSTAKRARTDTRIGANPVSVASAAVRLAQESFARLEDSSVLLVGAGETVELAARHLVQAKAKRLLIANRTLAHAQDLATRHGGVALPLSELERHLAEADIVLSATASREPILRKPQVAAALAARKHRPMLLLDLAVPRDIAADVAELKDVFLYTVDDLERAIEDNRRSRREAATEAEAIVELQVARFVETLAASTRTAPIKRLRDHGEAAREEVLAKAQAQLAAGQDPGEVLNFLAHTLTNRLLHAPTIALREAALTGNPELARAADKLFPAAGGMGTRSQEPGTGDSETAQAESLRDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKP7</accession>
    <name>A0A0S2DKP7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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    <dbReference type="PATRIC" id="fig|69.6.peg.3541"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="68" mass="6772" checksum="5C177F4896345EB4" modified="2016-02-17" version="1">MSAGRAGVARGGDGLGAGRRGRRGRRRARPGAAAPRDADRTGPGGRAIAAPMRGEILCPGAPGVKLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKQ4</accession>
    <name>A0A0S2DKQ4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase</fullName>
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        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_18450</name>
        <name evidence="3" type="ORF">GLE_3747</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
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    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="STRING" id="69.GLE_3747"/>
    <dbReference type="EnsemblBacteria" id="ALN59091">
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    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901605">
        <property type="term" value="P:alpha-amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="32"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="401" mass="43401" checksum="E8A865193D9F66FF" modified="2016-02-17" version="1">MPQLARRIGRAKPSAIMQVAEKAKRLKAEGRDIISFSIGVPNFLPGDHVYAAVREALAKDSGQYGSNRGADALLDAFIEHMGKIGLTGYGRVNCATGIGAKHVIYNIAEALLDEGDTIVFPTPYWTSYLDIAEIVNAKIDLLPCPASQDYKLTPAQLDAALAKKPKVFLFNNPSNPTGMVYSKDEIDALAAVVAKYPDTWVITDDIYNRMVFDGLGYHNFVHSRPELRDRVIFIDSLSKTYGMPGWRVGFMAGPEVIAQAVTTMNSNHITNVPEIVTAAAVAALSGPQDVPTQRCAEFQAKRDQVMAAMDSIPGVICPRPQGAFYVFPDISVAFGKTHQPSGLKIGNDMDLCNALLETKGVACVPGSAFGEPSALRISYTCPTPQLAPGLQRFQEFFAELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKR0</accession>
    <name>A0A0S2DKR0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">rplN</name>
        <name evidence="8" type="ORF">BV903_22985</name>
        <name evidence="10" type="ORF">D9T17_09480</name>
        <name evidence="9" type="ORF">FE772_18600</name>
        <name evidence="6" type="ORF">GLE_3780</name>
        <name evidence="7" type="ORF">LEN_1363</name>
        <name evidence="11" type="ORF">SAMN05421681_11013</name>
    </gene>
    <organism evidence="6 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 12">C3</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="journal article" date="2016" name="DNA Res." volume="0" first="0" last="0">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer, Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">M497-1</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="3">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">ATCC 29487</strain>
        </source>
    </reference>
    <reference evidence="7 15" key="4">
        <citation type="journal article" date="2017" name="DNA Res." volume="24" first="169" last="177">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
            <dbReference type="PubMed" id="28065880"/>
            <dbReference type="DOI" id=".1093/dnares/dsw055"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 15">M497-1</strain>
        </source>
    </reference>
    <reference evidence="8 14" key="5">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 14">B25</strain>
        </source>
    </reference>
    <reference evidence="10 16" key="6">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 16">OH11</strain>
        </source>
    </reference>
    <reference evidence="9 17" key="7">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP014940">
        <property type="protein sequence ID" value="BAV96850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000077">
        <property type="protein sequence ID" value="OPD61607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000023">
        <property type="protein sequence ID" value="ROU07191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNOG01000010">
        <property type="protein sequence ID" value="SDY03260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_031373826.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3780"/>
    <dbReference type="EnsemblBacteria" id="ALN59124">
        <property type="protein sequence ID" value="ALN59124"/>
        <property type="gene ID" value="GLE_3780"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAV96850">
        <property type="protein sequence ID" value="BAV96850"/>
        <property type="gene ID" value="LEN_1363"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61607">
        <property type="protein sequence ID" value="OPD61607"/>
        <property type="gene ID" value="BV903_22985"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY03260">
        <property type="protein sequence ID" value="SDY03260"/>
        <property type="gene ID" value="SAMN05421681_11013"/>
    </dbReference>
    <dbReference type="KEGG" id="lem:LEN_1363"/>
    <dbReference type="KEGG" id="lez:GLE_3780"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3724"/>
    <dbReference type="OMA" id="AKEVLCI"/>
    <dbReference type="OrthoDB" id="1799923at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000183696">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000218824">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_L14_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_L14P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005745">
        <property type="entry name" value="Ribosomal_L14P_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019972">
        <property type="entry name" value="Ribosomal_L14P_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="PTHR11761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="SSF50193"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01067">
        <property type="entry name" value="rplN_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00049">
        <property type="entry name" value="RIBOSOMAL_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAV96850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD61607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW27351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROU07191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="SDY03260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000183696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000218824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="122" mass="13461" checksum="5659D4659C5BDD81" modified="2016-02-17" version="1">MIQMQSYLGVADNSGAKEVMCIKVLGGSKRRYAHIGDIIKVTVKDAIPRGKVKKGDVYDAVVVRTRKGVRRPDGSLIRFDGNAAVLLNNKHEPIGTRIFGPVTRELRSEKFMKIVSLAPEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKV0</accession>
    <name>A0A0S2DKV0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HTH type transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3821</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3821"/>
    <dbReference type="EnsemblBacteria" id="ALN59164">
        <property type="protein sequence ID" value="ALN59164"/>
        <property type="gene ID" value="GLE_3821"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3821"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3763"/>
    <dbReference type="OMA" id="AWMAGEK"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="7"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="130" mass="13497" checksum="B8D9A4104876F6D7" modified="2016-02-17" version="1">MSLDTTLRLLAKASGLSVTDLATAIPRAGANTVSAWLRGEKLPGRDQLDALARAFGVPAGALLAELASTLDPARTQGEHDLLAAYRALDTRQQGALLEVAASMAGTRRAAPARARKAPAKKASARKKAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL26</accession>
    <name>A0A0S2DL26_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Prepilin-type N-terminal cleavage/methylation domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Type IV pilus assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pilW</name>
        <name evidence="3" type="ORF">BV903_24295</name>
        <name evidence="2" type="ORF">GLE_3624</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000092">
        <property type="protein sequence ID" value="OPD61323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948425.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000092.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3624"/>
    <dbReference type="EnsemblBacteria" id="ALN58968">
        <property type="protein sequence ID" value="ALN58968"/>
        <property type="gene ID" value="GLE_3624"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61323">
        <property type="protein sequence ID" value="OPD61323"/>
        <property type="gene ID" value="BV903_24295"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3624"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3568"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043683">
        <property type="term" value="P:type IV pilus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032092">
        <property type="entry name" value="PilW"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16074">
        <property type="entry name" value="PilW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="403" mass="42548" checksum="389171C791CB2AD2" modified="2016-02-17" version="1">MTRLRRASGFSLIELMVALVLGALLVLGLLKIFDASRASYKLSEGLARVQENGRFAMDYLQRDLRMAGHMGCLNDQTRFLSNPAGFRSAFVAQQRPSEAQLDAAPDALRFNHMIQGFEARGTAPGGSVGLPANGAWAGSPNLPGHVAALTPAPMAGSDVVAVRFFSPEGVPVKAFSASSVTVDSARWNQVIAANGYVRPGLLAVADCQSAISFEATSIDQSGADTVIGVAVSGLNRSGLGEGPFSPGQATLYRAETMVYYVAPNPEAGNEPTLYRARFTAEPGAATATLVGGAPEPLVEGIENMQLIYGLDSQTDQTRQPTGFVSRQAVADAVQPGADRLPWRRVGLVQVAFLLRSADGAGAPASLIAEKPRLLGVQTAPPDDGRYRTVYESTIALRNRLFGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLG7</accession>
    <name>A0A0S2DLG7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidoglycan D,D-transpeptidase FtsI</fullName>
            <ecNumber evidence="7">3.4.16.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Penicillin-binding protein 3</fullName>
            <shortName evidence="7">PBP-3</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ftsI</name>
        <name evidence="11" type="ORF">GLE_4136</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the transpeptidase family. FtsI subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.4" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4136"/>
    <dbReference type="EnsemblBacteria" id="ALN59478">
        <property type="protein sequence ID" value="ALN59478"/>
        <property type="gene ID" value="GLE_4136"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4136"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4078"/>
    <dbReference type="OMA" id="HGKEEYY"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02080">
        <property type="entry name" value="FtsI_transpept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037532">
        <property type="entry name" value="FtsI_transpept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005311">
        <property type="entry name" value="PBP_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036138">
        <property type="entry name" value="PBP_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03717">
        <property type="entry name" value="PBP_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56519">
        <property type="entry name" value="SSF56519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0717">Septation</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_dimer" evidence="10">
        <location>
            <begin position="109"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="9">
        <location>
            <begin position="299"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="620"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="7">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN59478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="673" mass="72230" checksum="3D755E7B4E03F58D" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLI3</accession>
    <name>A0A0S2DLI3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Outer membrane protein assembly factor BamD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">yfiO</name>
        <name evidence="1" type="synonym">bamD</name>
        <name evidence="5" type="ORF">FE772_20130</name>
        <name evidence="4" type="ORF">GLE_4105</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the Bam complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the BamD family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948787.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4105"/>
    <dbReference type="EnsemblBacteria" id="ALN59447">
        <property type="protein sequence ID" value="ALN59447"/>
        <property type="gene ID" value="GLE_4105"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4105"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4047"/>
    <dbReference type="OMA" id="VERQHPY"/>
    <dbReference type="OrthoDB" id="1256747at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051205">
        <property type="term" value="P:protein insertion into membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd15830">
        <property type="entry name" value="BamD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00922">
        <property type="entry name" value="OM_assembly_BamD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017689">
        <property type="entry name" value="BamD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039565">
        <property type="entry name" value="BamD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13525">
        <property type="entry name" value="YfiO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03302">
        <property type="entry name" value="OM_YfiO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="YfiO" evidence="3">
        <location>
            <begin position="46"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="281"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW27602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="305" mass="34596" checksum="D1D75441B51327B1" modified="2016-02-17" version="1">MTERSTPSRAVVRLVSLLLIVAVAGTGCSRVGKMFKKNKDADEGQPVEAIYEKAHKSMTNGNWASAELSFKRLVAQYPYGPYTEQALIETAYAQYKSGKHDDAISSIDRFIRTYPTHRNIAYLYYLRGLVNSSRDTVFLQKVWRLDVSRRDLATPMQAYNDFQIVVERYPNSRYAQDARKRMIVLRDTFARHELDVSLYYLRRTAYVAAADRAKYLLETYPQSGYQNDAVAVLMKSYEGLANPTLAADAKRVLQQNDAGHPALTGDWPDYPSNLRKLNPFAGERSAVDNRDKLEAKRAEQAGKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLI5</accession>
    <name>A0A0S2DLI5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HTH type transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_23425</name>
        <name evidence="4" type="ORF">FE772_18830</name>
        <name evidence="2" type="ORF">GLE_3824</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000082">
        <property type="protein sequence ID" value="OPD61479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
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        <property type="nucleotide sequence ID" value="NZ_MTAY01000082.1"/>
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        <property type="protein sequence ID" value="ALN59167"/>
        <property type="gene ID" value="GLE_3824"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61479">
        <property type="protein sequence ID" value="OPD61479"/>
        <property type="gene ID" value="BV903_23425"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3824"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3766"/>
    <dbReference type="OMA" id="DGPMERY"/>
    <dbReference type="OrthoDB" id="1607334at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="HTH_26"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF47413"/>
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    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="11"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="246" mass="27834" checksum="A6A43576A47AF6EE" modified="2016-02-17" version="1">MALSLELVDALKRFLRAQDLTYRDLAGRLKLSEAAVKRMFSRRAMSLARLEEICDVLDIGLAELSAEAGRGRAPMATLSEAQEQALVDEPALLLALFLTLNRWKQADVQAHFNFDNARWTGLLVRLDRLGIIELMPGNRGRPLTARNFRWRADGPMERYFRLKLLQDYFADPFDGEQDVLLLLSGSLSPAGIRQLKQRLGEVAREFDALLARDAALTAQERVGVSLVLAQKPWLLQLFQPYRRSQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLV3</accession>
    <name>A0A0S2DLV3_LYSEN</name>
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        <submittedName>
            <fullName evidence="5">Type IV pilus assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pilB</name>
        <name evidence="5" type="ORF">GLE_4116</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GSP E family.</text>
    </comment>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009297">
        <property type="term" value="P:pilus assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037257">
        <property type="entry name" value="T2SS_E_N_sf"/>
    </dbReference>
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        <property type="entry name" value="T2SS_GspE_N"/>
    </dbReference>
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        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05157">
        <property type="entry name" value="T2SSE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF160246"/>
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        <property type="entry name" value="SSF52540"/>
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    </dbReference>
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        <property type="entry name" value="type_IV_pilB"/>
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    </dbReference>
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        <property type="entry name" value="T2SP_E"/>
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    </dbReference>
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    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="386"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="567" mass="61696" checksum="2C15B7F003D48469" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMU9</accession>
    <name>A0A0S2DMU9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_21400</name>
        <name evidence="1" type="ORF">GLE_4380</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949006.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4380"/>
    <dbReference type="EnsemblBacteria" id="ALN59721">
        <property type="protein sequence ID" value="ALN59721"/>
        <property type="gene ID" value="GLE_4380"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4380"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4319"/>
    <dbReference type="OMA" id="CEYREEA"/>
    <dbReference type="OrthoDB" id="700052at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="308" mass="34196" checksum="90D7AD0A94453E02" modified="2016-02-17" version="1">MIRPLHARLLVDFASGPGALVAFGAGPDRALYALHALRPVDYRTAGPGPSYPKINPARPQDYRARAWLDGQCVLDLRIDGERYNVHALQPLGDDLLLACARSGGSAGRHNGRVYSRDGRLLRELALGDGIEHLQTTPRGAIWTGYFDEGVFGDDPVSACGLAAWDAHGANTYQYQPEDGLDTICDCYALNVADERETWLCYYTEFALVLLRERRLAGHWRPPFEGAKAMAVRGRHALMYRHPRRGHEAALFRLEDDGRCAELARFELRREDGAPLRPERVDGRGDTLYFVADGCAWTVSLEQAMAAAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMZ7</accession>
    <name>A0A0S2DMZ7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4597"/>
    <dbReference type="EnsemblBacteria" id="ALN59938">
        <property type="protein sequence ID" value="ALN59938"/>
        <property type="gene ID" value="GLE_4597"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4597"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4532"/>
    <dbReference type="OMA" id="GYPGHIT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="1">
        <location>
            <begin position="24"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="520" mass="57171" checksum="5899585CD73516AA" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN34</accession>
    <name>A0A0S2DN34_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RHS repeat protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Rhs family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_22700</name>
        <name evidence="2" type="ORF">GLE_4657</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949217.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4657"/>
    <dbReference type="EnsemblBacteria" id="ALN59998">
        <property type="protein sequence ID" value="ALN59998"/>
        <property type="gene ID" value="GLE_4657"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4657"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4593"/>
    <dbReference type="OrthoDB" id="1639867at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031325">
        <property type="entry name" value="RHS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006530">
        <property type="entry name" value="YD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05593">
        <property type="entry name" value="RHS_repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01643">
        <property type="entry name" value="YD_repeat_2x"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="889"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1045"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1103"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="901"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="930"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="954"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="999"/>
            <end position="1013"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="1142" mass="123507" checksum="3413D5A6A662E017" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN49</accession>
    <name>A0A0S2DN49_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FHIPEP family type III secretion protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Flagellar biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">flhA</name>
        <name evidence="9" type="ORF">FE772_22565</name>
        <name evidence="8" type="ORF">GLE_4627</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949193.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4627"/>
    <dbReference type="EnsemblBacteria" id="ALN59968">
        <property type="protein sequence ID" value="ALN59968"/>
        <property type="gene ID" value="GLE_4627"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4627"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4563"/>
    <dbReference type="OMA" id="PAVWIEH"/>
    <dbReference type="OrthoDB" id="436367at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042194">
        <property type="entry name" value="FHIPEP_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042193">
        <property type="entry name" value="FHIPEP_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042196">
        <property type="entry name" value="FHIPEP_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001712">
        <property type="entry name" value="T3SS_FHIPEP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30161">
        <property type="entry name" value="PTHR30161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00771">
        <property type="entry name" value="FHIPEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005419">
        <property type="entry name" value="FlhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00949">
        <property type="entry name" value="TYPE3IMAPROT"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="19"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="243"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="280"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="303"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW28012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="706" mass="76011" checksum="A079B3FA09F6BF6D" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN57</accession>
    <name>A0A0S2DN57_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4386</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59727">
        <property type="protein sequence ID" value="ALN59727"/>
        <property type="gene ID" value="GLE_4386"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4386"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4325"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="56" mass="6041" checksum="491ECE05FA020AE0" modified="2016-02-17" version="1">MGGPSGPTLSDPTQRSDLSRKHRGSSPSHQSEPSHGMLLWEGLQARCLSIPRDEAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNC5</accession>
    <name>A0A0S2DNC5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BV903_14025</name>
        <name evidence="6" type="ORF">GLE_4582</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000036">
        <property type="protein sequence ID" value="OPD63251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949161.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4582"/>
    <dbReference type="EnsemblBacteria" id="ALN59923">
        <property type="protein sequence ID" value="ALN59923"/>
        <property type="gene ID" value="GLE_4582"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63251">
        <property type="protein sequence ID" value="OPD63251"/>
        <property type="gene ID" value="BV903_14025"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4582"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4518"/>
    <dbReference type="OMA" id="GCRRIDI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="23"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="5">
        <location>
            <begin position="232"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD63251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="506" mass="54384" checksum="4E9ECE17C010AAA0" modified="2016-02-17" version="1">MDETAARPTPAARAPTRRWWSGLFWKCLLSMLTACWISTILLSLLGVYLLRRELRDDMAPPALETSMRRELAQLGPMPDLAAVSPAQCQALLQGLLVRVVGMDTPKWMYSHSFAGGAADGRIAIRYRDRDGRVCLYPERPSAPLARALEQAGQDVAADGVAAARTLDRDGDWVSVAALPLAGAPGASLGVGQHAADTTATFLRMSSGESGDMVWLAFYLLVISAMASVAVATLLTRRIGHAEQVADSWAAGGLDARIHDRGRDEFGGLAHRFDRMADALGEVIQVRQQLAVSEERNRLARDLHDTAKQRSFALGLQLSVLDHLNGRDGEAGRDPRQGALIKAALGLTGQLQRDLADVIQRFTAPTVAEQGLRKALEDTFSHLLGGSGIEWRLLLDGVAERGVGAHHQHAGQLLLIATEAASNSLRHSGARRIEVVLNSADERYGWTIQDDGCGFAVNEHESTGMGLGNMRMRARTLPGGRFRIASSASGTVVTVSFTLPAPQGESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNF3</accession>
    <name>A0A0S2DNF3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">ABC transporter, ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_22960</name>
        <name evidence="5" type="ORF">GLE_4723</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949261.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4723"/>
    <dbReference type="EnsemblBacteria" id="ALN60064">
        <property type="protein sequence ID" value="ALN60064"/>
        <property type="gene ID" value="GLE_4723"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4723"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4657"/>
    <dbReference type="OMA" id="PVMFMDE"/>
    <dbReference type="OrthoDB" id="1926714at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="17"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="50"/>
            <end position="57"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW28077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="327" mass="35645" checksum="D5DF163ED36687F7" modified="2016-02-17" version="1">MPPQTPASPTPAADAIVSIQGLTKTYAGGFQALKRVDLDIRRGEIFALLGPNGAGKTTLISIVCGIVNPGEGRVLADGHDIVRDYRAARAAIGLVPQELHTDAFETVWDTVRFSRGLFGKAPDPAYLEKLLRELALWDKRGEKIMALSGGMKRRVLIAKALSHEPRILFLDEPTAGVDVELRREMWAMVSRLRENGTTIILTTHYIEEAEEMADRVGVINKGEIVLVEDTRALMRKLGKKQLTLQLQAPLAALPAGLANDALALSADGNELVYTFDAQAEDTGIAALLKRLAEHGIEFKDLRTAQSSLEEIFVNLVKAPRPAQEARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNH4</accession>
    <name>A0A0S2DNH4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4712</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4712"/>
    <dbReference type="EnsemblBacteria" id="ALN60053">
        <property type="protein sequence ID" value="ALN60053"/>
        <property type="gene ID" value="GLE_4712"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4712"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4646"/>
    <dbReference type="OMA" id="NGPHAHM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011048">
        <property type="entry name" value="Haem_d1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019405">
        <property type="entry name" value="Lactonase_7-beta_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10282">
        <property type="entry name" value="Lactonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51004">
        <property type="entry name" value="SSF51004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="377" mass="39689" checksum="8B602257007377CE" modified="2016-02-17" version="1">MSAAIAHAETAPVELLVGCYTGGQCEGVGRYRFDPASGRIDPRPLETIVTDNPSWLTVSADGARLFAVNENGPASPDPVGRASSFALGRGAARSRALSRANTLGDDPAHAALGRDGRYLFVSNYSGAQSPGGSLAVLPVDADGRLGAAVQVLGHRASQADRERQLGPHVHAAAQSPDGRYVFAADLGADKVYAYRYDPARSAERPLLAATTPWLELPAGSGPRHLLFSADGRHAYLTLEMSGEIVALDHDDGRLRIVQTLALDPGRRQGNAAAALHLSADGRFLYASNRGEDNHIAVYAVDPGDGRLRPLQRRASEGRGPREFALAPDGRHVVVANQHSGNLAVIARDPASGELGATVQTLPMVSPSDVKFMPGPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNN2</accession>
    <name>A0A0S2DNN2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Sulfate ABC transporter permease subunit CysW</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="11">Sulfate ABC transporter, permease protein cysW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">cysW</name>
        <name evidence="12" type="ORF">BV903_12170</name>
        <name evidence="13" type="ORF">FE772_24190</name>
        <name evidence="11" type="ORF">GLE_4990</name>
    </gene>
    <organism evidence="11 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">C3</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">B25</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000029">
        <property type="protein sequence ID" value="OPD63673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949467.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000029.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4990"/>
    <dbReference type="EnsemblBacteria" id="ALN60331">
        <property type="protein sequence ID" value="ALN60331"/>
        <property type="gene ID" value="GLE_4990"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63673">
        <property type="protein sequence ID" value="OPD63673"/>
        <property type="gene ID" value="BV903_12170"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4990"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4918"/>
    <dbReference type="OMA" id="CVSKYSF"/>
    <dbReference type="OrthoDB" id="1110665at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015419">
        <property type="term" value="F:ABC-type sulfate transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011866">
        <property type="entry name" value="CysW_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005667">
        <property type="entry name" value="Sulph_transpt2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30406">
        <property type="entry name" value="PTHR30406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30406:SF1">
        <property type="entry name" value="PTHR30406:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00969">
        <property type="entry name" value="3a0106s02"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02140">
        <property type="entry name" value="permease_CysW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0764">Sulfate transport</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="61"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="97"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="199"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="246"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="61"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN60331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OPD63673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW28283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="285" mass="30573" checksum="2D6E8473389C6CC4" modified="2016-02-17" version="1">MAERDHLQEPAWVRWLLIGLAAAIMLLVVVLPLFALLGAAFGSGLAVWWNAVAEEHTVAALKLTLLTAAIVVPVNAVCGVFAAWALTRFEFRGKRALLSLIDLPFAVSPVVAGLCLVLLFSPTHGFLKDVLNAYDLKILFATPGIVLATLFVTFPFVVRELIPLMEQQGSDEELAARSLGANAWTMFFKVTLPNIKWGLLYGVLLCSARAMGEFGAVTVVSGNVMGSTNTLSLHVEVLYKQLGGEAAAAFAAASLLAGLALVTLVVKLWLETRHGDALAQSHRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNV4</accession>
    <name>A0A0S2DNV4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4716</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60057">
        <property type="protein sequence ID" value="ALN60057"/>
        <property type="gene ID" value="GLE_4716"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4716"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4650"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="80" mass="8636" checksum="918B962D61326C26" modified="2016-02-17" version="1">MPRAVRAAPRPSWPVAGPSLDGGDRTLHQAVFAFRYDAVRFFRGPSARHNERPRTAGPRTGERAAAPVAPIPPCRPPPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNZ1</accession>
    <name>A0A0S2DNZ1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein YcgK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4868</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949375.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4868"/>
    <dbReference type="EnsemblBacteria" id="ALN60209">
        <property type="protein sequence ID" value="ALN60209"/>
        <property type="gene ID" value="GLE_4868"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4868"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4799"/>
    <dbReference type="OMA" id="RGETANY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595480" evidence="1">
        <location>
            <begin position="28"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="148" mass="15641" checksum="71E298231AE78C94" modified="2016-02-17" version="1">MHFSPARFARIAVLSLALATAAGAVGAADKVVTVPVKFAKGTTGVTVKGAIKGYDSVEYLVVARAGQTLRLTISGSTNANVNVFPPRANGTPDPDADGLELSSDYQNGRSSERAVLPANGTYRIQVYQFRAIARRGTVSKFSLKIDIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP20</accession>
    <name>A0A0S2DP20_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Beta-ketoacyl synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_4967</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949450.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4967"/>
    <dbReference type="EnsemblBacteria" id="ALN60308">
        <property type="protein sequence ID" value="ALN60308"/>
        <property type="gene ID" value="GLE_4967"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4967"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4894"/>
    <dbReference type="OMA" id="INDANHI"/>
    <dbReference type="OrthoDB" id="606297at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="4">
        <location>
            <begin position="43"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="399" mass="41196" checksum="228010E5BB73AB7B" modified="2016-02-17" version="1">MPPLAIRAYTATTALGRGLDAQARALRERRGGLRRNDFPTTAPQQAPLDCWIGRVDGLEDAPLPAHLAVWECRNNRLAWLSLQHDGVVEAAAALAARYGAERVAVIVGTSTASIGATEEAYAGLRGDPPRFPPSLSRAHLHTPHSPGAFVAAATGLRGPCVTVATACSSSAKVFAQAARLIGAGLADAALVGGVDTLCGSVLFGFNSLQLVSPDPCLPFDAHRTGLSLGEAGGFAVLERCGADEAGLQLRGYGESSDAHHMSTPHPQGLGARLAMADALARAGVEPAEIGYLNLHGTATPANDQVEALAVASLFPPQLHASSTKGWTGHTLGAAGIVESAFALLALQSGELPGTLNSREPDPGNGPQIRFDNARAPIRYAMNNSFGFGGNNCSLVFARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP47</accession>
    <name>A0A0S2DP47_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4867</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60208">
        <property type="protein sequence ID" value="ALN60208"/>
        <property type="gene ID" value="GLE_4867"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4867"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="47" mass="5009" checksum="28F34425A0B730B8" modified="2016-02-17" version="1">MQLLQSEAQATGAPVGAAQAATAPSLLRRKFRRSRRFAVATRVAPTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP65</accession>
    <name>A0A0S2DP65_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sulfate transport system permease protein CysT</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">cysT</name>
        <name evidence="11" type="ORF">GLE_4989</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.</text>
    </comment>
    <comment type="function">
        <text evidence="8">Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4989"/>
    <dbReference type="EnsemblBacteria" id="ALN60330">
        <property type="protein sequence ID" value="ALN60330"/>
        <property type="gene ID" value="GLE_4989"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4989"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4917"/>
    <dbReference type="OMA" id="AQLTWDQ"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015419">
        <property type="term" value="F:ABC-type sulfate transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011865">
        <property type="entry name" value="CysT_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005667">
        <property type="entry name" value="Sulph_transpt2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30406">
        <property type="entry name" value="PTHR30406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30406:SF8">
        <property type="entry name" value="PTHR30406:SF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00969">
        <property type="entry name" value="3a0106s02"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02139">
        <property type="entry name" value="permease_CysT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0764">Sulfate transport</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="197"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="243"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="61"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN60330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="280" mass="29672" checksum="BEC288049968D59E" modified="2016-02-17" version="1">MPASGRWRRPLPGFGLGLGIGLTWLGLIVLLPLAALILRSGGLGWAGWARAISDSRVIASLKVSFGASFVAAVAALLFGALIAWVLVRYRFPGRRLMDALVDLPFALPTAVAGITLAAIYDENGWVGQLLQPFGIQLVNNFTGIVIALIFVGLPFAVRTVQPVLEALGREQEEAAISLGASRLTTLRRVILPELLPALLTGFALAFARALGEFGSVIFISGNLPWKTEIAPMLITIRLEEDGGVPAAIVLATLLLLMSFACLLAINAASTLFAHGNRRDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPD7</accession>
    <name>A0A0S2DPD7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Beta-N-acetylhexosaminidase</fullName>
            <ecNumber evidence="3">3.2.1.52</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Beta-N-acetylhexosaminidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">N-acetyl-beta-glucosaminidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FE772_25000</name>
        <name evidence="11" type="ORF">GLE_5161</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 20 family.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949598.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5161"/>
    <dbReference type="EnsemblBacteria" id="ALN60502">
        <property type="protein sequence ID" value="ALN60502"/>
        <property type="gene ID" value="GLE_5161"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5161"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5084"/>
    <dbReference type="OMA" id="VDWGVNP"/>
    <dbReference type="OrthoDB" id="727559at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004563">
        <property type="term" value="F:beta-N-acetylhexosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102148">
        <property type="term" value="F:N-acetyl-beta-D-galactosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025705">
        <property type="entry name" value="Beta_hexosaminidase_sua/sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015883">
        <property type="entry name" value="Glyco_hydro_20_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015882">
        <property type="entry name" value="HEX_bac_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600">
        <property type="entry name" value="PTHR22600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00728">
        <property type="entry name" value="Glyco_hydro_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02838">
        <property type="entry name" value="Glyco_hydro_20b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00738">
        <property type="entry name" value="GLHYDRLASE20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="SSF55545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242357" description="Beta-N-acetylhexosaminidase" evidence="8">
        <location>
            <begin position="24"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_20b" evidence="10">
        <location>
            <begin position="67"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_20" evidence="9">
        <location>
            <begin position="198"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="42"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN60502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW28423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="814" mass="87765" checksum="4D2AE8CA3875C348" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPI5</accession>
    <name>A0A0S2DPI5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutathione hydrolase proenzyme</fullName>
            <ecNumber evidence="4">2.3.2.2</ecNumber>
            <ecNumber evidence="4">3.4.19.13</ecNumber>
        </recommendedName>
        <component>
            <recommendedName>
                <fullName evidence="4">Glutathione hydrolase large chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="4">Glutathione hydrolase small chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="6" type="primary">ggt</name>
        <name evidence="6" type="ORF">GLE_5169</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 4">
            <text>an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:59468"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="ChEBI" id="CHEBI:143103"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>an alpha-amino acid + an N-terminal (5-L-glutamyl)-[peptide] = 5-L-glutamyl amino acid + N-terminal L-alpha-aminoacyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:23904"/>
            <dbReference type="Rhea" id="RHEA-COMP:9780"/>
            <dbReference type="Rhea" id="RHEA-COMP:9795"/>
            <dbReference type="ChEBI" id="CHEBI:77644"/>
            <dbReference type="ChEBI" id="CHEBI:78597"/>
            <dbReference type="ChEBI" id="CHEBI:78599"/>
            <dbReference type="ChEBI" id="CHEBI:78608"/>
            <dbReference type="EC" id="2.3.2.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>glutathione + H2O = L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:28807"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:61694"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Sulfur metabolism; glutathione metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.</text>
    </comment>
    <comment type="PTM">
        <text evidence="4">Cleaved by autocatalysis into a large and a small subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the gamma-glutamyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.2" evidence="4"/>
    <dbReference type="EC" id="3.4.19.13" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949605.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5169"/>
    <dbReference type="EnsemblBacteria" id="ALN60510">
        <property type="protein sequence ID" value="ALN60510"/>
        <property type="gene ID" value="GLE_5169"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5169"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5091"/>
    <dbReference type="OMA" id="MFCLFYD"/>
    <dbReference type="OrthoDB" id="803717at2"/>
    <dbReference type="UniPathway" id="UPA00204"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036374">
        <property type="term" value="F:glutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102953">
        <property type="term" value="F:hypoglycin A gamma-glutamyl transpeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103068">
        <property type="term" value="F:leukotriene C4 gamma-glutamyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006750">
        <property type="term" value="P:glutathione biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006751">
        <property type="term" value="P:glutathione catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043138">
        <property type="entry name" value="GGT_lsub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000101">
        <property type="entry name" value="GGT_peptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043137">
        <property type="entry name" value="GGT_ssub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00066">
        <property type="entry name" value="g_glut_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595570" description="Glutathione hydrolase proenzyme" evidence="5">
        <location>
            <begin position="34"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN60510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="581" mass="62558" checksum="6334659B187D3FE0" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPK1</accession>
    <name>A0A0S2DPK1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4763</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60104">
        <property type="protein sequence ID" value="ALN60104"/>
        <property type="gene ID" value="GLE_4763"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4763"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4696"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="76" mass="8599" checksum="8C3D32BA1BB7E4D9" modified="2016-02-17" version="1">MFWLEPQPVDFMSIAVAAEPCFPTERALRLTQAKLHTKERAPGAQTYDAIQNGVMVSFSTTPDEKCVSYIHIELDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPW5</accession>
    <name>A0A0S2DPW5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">uvrD</name>
        <name evidence="10" type="synonym">mutU</name>
        <name evidence="10" type="synonym">recL</name>
        <name evidence="10" type="ORF">FE772_23980</name>
        <name evidence="9" type="ORF">GLE_4946</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949435.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4946"/>
    <dbReference type="EnsemblBacteria" id="ALN60287">
        <property type="protein sequence ID" value="ALN60287"/>
        <property type="gene ID" value="GLE_4946"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4946"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4874"/>
    <dbReference type="OMA" id="YQDTNRT"/>
    <dbReference type="OrthoDB" id="137860at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006268">
        <property type="term" value="P:DNA unwinding involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005753">
        <property type="entry name" value="DNA_helicase_ATP-dep_UvrD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01075">
        <property type="entry name" value="uvrD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51217">
        <property type="entry name" value="UVRD_HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="7">
        <location>
            <begin position="8"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="8">
        <location>
            <begin position="287"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="29"/>
            <end position="36"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN60287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW28249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="725" mass="81203" checksum="01FB2DC8EA139531" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPZ4</accession>
    <name>A0A0S2DPZ4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4907</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949406.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4907"/>
    <dbReference type="EnsemblBacteria" id="ALN60248">
        <property type="protein sequence ID" value="ALN60248"/>
        <property type="gene ID" value="GLE_4907"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4907"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4837"/>
    <dbReference type="OMA" id="SNFLTHW"/>
    <dbReference type="OrthoDB" id="846433at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="7"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="300" mass="32861" checksum="52E57A5A2A056023" modified="2016-02-17" version="1">MSGRRLPPLSALRAFEAAARLRSFKRAAQELSVTPTAISHQIRGLEEHIGVRLFERQTRRVVPTAAAERLFPVLRDGFDAFAAAVEALRAQPQRRALTLSATLSFTAKWLVPRMASFRQACPDLDLRLHASDDPVDLHAGLADAAIRYGRGPWPGLSAEPLVHNRFAPVCSPHLGLRRPQDLQRHALLHSEWRHPTADTPTWQRWRERASADGLDFGDLDFDAGLRFTDESHAIQAAIAGHGVALLSLALVADDLAAGALVQPFGPVLDGYPHWLVQAPGAERADLAALRAWLRAQADVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ04</accession>
    <name>A0A0S2DQ04_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA polymerase factor sigma-70 subfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_5203</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949631.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5203"/>
    <dbReference type="EnsemblBacteria" id="ALN60544">
        <property type="protein sequence ID" value="ALN60544"/>
        <property type="gene ID" value="GLE_5203"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5203"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5122"/>
    <dbReference type="OMA" id="SAKRYAW"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="3">
        <location>
            <begin position="13"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="4">
        <location>
            <begin position="105"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="171" mass="19364" checksum="852ED52131BF4816" modified="2016-02-17" version="1">MSPHELDQALREQLPSLRRFARWLARDPHAADDLVQSALERAIAGWSQRRDEAALRPWLFSILYRQFLDGQRRAQRYAGLLARIGLGAADSQPSAERETLARSTLEALQRLPVEQRSLLLWVSVEGLSYQEVADILEVPIGTVMSRLSRARQALRRLSDGETATAPLRLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQD8</accession>
    <name>A0A0S2DQD8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_5099</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949552.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60440">
        <property type="protein sequence ID" value="ALN60440"/>
        <property type="gene ID" value="GLE_5099"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5099"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5024"/>
    <dbReference type="OrthoDB" id="1973929at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="390"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="418" mass="40622" checksum="4FE2AEDC579DEEF0" modified="2016-02-17" version="1">MSIDFPSNPLGNLLSGLGGGASGLPGGLPLLGGNGPGLPGMPSAPGEGDNDPQSPRLPSNNLPGANGQGPGGTPGLPGGGLGNTPVGTAPAPGSNAPLINPDNPLSRMLQGSSPSAYNHPFGNGPAPTQYPAPTLSERAFNAAQYALLDRGAVPAAASSAASAGAQGQSLPAAVGGALPGGGSAGGAAAGAAAHGAATTAQLSAAPASTLAAANVVPNAVAGSPAAAALSQDALIAQQALLARLPAGTHAVAGNTAAAATAPPSETAAALPAVGTHTTSNDPRNLPAALNDRAMQQRGDGPNASVYTGDTAARRAPGRGRVSGATLTHWLWRFGRGGAHRPSHDDTPEVEAVRALQWLFWVLTVVAYVCLAMAVVLLLPGGSFDSQRIQTGGSGAALALGVAVAAGAWWLGRRINKRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQF8</accession>
    <name>A0A0S2DQF8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_5368</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949753.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5368"/>
    <dbReference type="EnsemblBacteria" id="ALN60709">
        <property type="protein sequence ID" value="ALN60709"/>
        <property type="gene ID" value="GLE_5368"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5368"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5283"/>
    <dbReference type="OMA" id="FCKISPE"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="10"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="147"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN60709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="365" mass="40336" checksum="6C21EAFC70DB3D2B" modified="2016-02-17" version="1">MSTPATSTGRILVVDDQAANLRVVTALLSRQGYEVVAASTGDEALELYAQSPPDLILLDVMMPGMDGFEVMAALRADSPLRVPVVFVTAAHDRDLLLRAFDAGVVDYVTKPFLPEELLARVNAHVGLKLTRDRLERVAREREELVNLVAHDLKNPLTSVLFASDLLINNGCKPERVPRYLQMIHESADDALGYIRHYLESQAGHRERAEQEEGIRADLAETLDWLVRRYEMQLDARGIRVQVQPPANGAAQVAMDPRVLRQVSENLVTNAMKYAPGSDLTLAARNSAPGFWQLIVADRGPGIPVARQRELFKPFVRLHEADIDDGLSSGLGLSLAKQIVVNAGGQLWYEERKHGGSRFIIELPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DR16</accession>
    <name>A0A0S2DR16_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5532</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60873">
        <property type="protein sequence ID" value="ALN60873"/>
        <property type="gene ID" value="GLE_5532"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5532"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5451"/>
    <dbReference type="OrthoDB" id="358978at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="164" mass="17881" checksum="830187AE904013E5" modified="2016-02-17" version="1">MADFERLGEAVARARGLAPGAFQSRYADLVRAGIDRALDGNPVAQALDKLLRRDTPPWIGTAGQLYEQLGHLCGPDRTAWPRSPKGLSDQLRRVAPAYRAKGIEIEHRGHTRDGAVWKIARHPAGRADRDYPVSASADTHPPRELDAAEAAARRPSRPRKGASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2004-09-13" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>Q6BCF8</accession>
    <name>Q6BCF8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Chitinase A</fullName>
            <ecNumber evidence="11">3.2.1.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">chiA</name>
        <name evidence="11" type="synonym">chiA1</name>
        <name evidence="11" type="ORF">GLE_1126</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2004-06" db="EMBL/GenBank/DDBJ databases">
            <title>The chiA gene encodes for major chitinase activity expressed by Lysobacter enzymogenes C3.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
                <person name="Reedy R.M."/>
                <person name="Bick J."/>
                <person name="Yuen G.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">C3</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="11"/>
    <dbReference type="EMBL" id="AY667480">
        <property type="protein sequence ID" value="AAT77163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="Q6BCF8"/>
    <dbReference type="STRING" id="69.GLE_1126"/>
    <dbReference type="CAZy" id="CBM12">
        <property type="family name" value="Carbohydrate-Binding Module Family 12"/>
    </dbReference>
    <dbReference type="CAZy" id="GH18">
        <property type="family name" value="Glycoside Hydrolase Family 18"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56484">
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</entry>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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</entry>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55507.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="656" mass="70703" checksum="652671BDDFFC700D" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAK0</accession>
    <name>A0A0S2DAK0_LYSEN</name>
    <protein>
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        </submittedName>
        <submittedName>
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        </submittedName>
    </protein>
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    </gene>
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        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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        </lineage>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">B25</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000068">
        <property type="protein sequence ID" value="OPD61922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_0200"/>
    <dbReference type="EnsemblBacteria" id="ALN55559">
        <property type="protein sequence ID" value="ALN55559"/>
        <property type="gene ID" value="GLE_0200"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61922">
        <property type="protein sequence ID" value="OPD61922"/>
        <property type="gene ID" value="BV903_21235"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0200"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.202"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011206">
        <property type="entry name" value="Citrate_lyase_beta/mcl1/mcl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015582">
        <property type="entry name" value="Cit_lyase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH_HpaI" evidence="5">
        <location>
            <begin position="2"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="65"/>
        </location>
        <ligand>
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    <feature type="binding site" evidence="3 4">
        <location>
            <position position="127"/>
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    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR015582-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR015582-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN55559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD61922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="284" mass="29598" checksum="B69692115C340D85" modified="2016-02-17" version="1">MRSKLFVPGARPELFDKALAGAADALSFDLEDAVAPERKAAARVAVAAFLASSAVAASSKLMIVRVNAPASEHFAADLAAVAREGADLINLPKIESADALHEAVAALERAEARNGVVRPIGLLVNIETPRALRAAASIAGAHPRVAGLQLGLADLFEAQGIARDDRANVHAALFAVRMAAAEAGVFALDGAYADLHDEAGYFDEALVAKRLGFLGKTCLHPRQVGLANRAFAASADEIARARRIVSAAETAADGGRGVFVVDGRMIDRPFLKRAQALLATAERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAY9</accession>
    <name>A0A0S2DAY9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Dipeptidyl aminopeptidase/acylaminoacyl peptidase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">S9 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_02335</name>
        <name evidence="5" type="ORF">GLE_0304</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S9C family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945939.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0304"/>
    <dbReference type="EnsemblBacteria" id="ALN55662">
        <property type="protein sequence ID" value="ALN55662"/>
        <property type="gene ID" value="GLE_0304"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0304"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.301"/>
    <dbReference type="OMA" id="HEVYRYD"/>
    <dbReference type="OrthoDB" id="154149at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002470">
        <property type="entry name" value="Peptidase_S9A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00862">
        <property type="entry name" value="PROLIGOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726717" evidence="3">
        <location>
            <begin position="23"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="4">
        <location>
            <begin position="444"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN55662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW24681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="664" mass="72889" checksum="B97514711F8BDD7E" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB09</accession>
    <name>A0A0S2DB09_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0348</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55706">
        <property type="protein sequence ID" value="ALN55706"/>
        <property type="gene ID" value="GLE_0348"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0348"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.345"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="43" mass="4560" checksum="1D8AFAAFA35BA724" modified="2016-02-17" version="1">MSRRAGAAAAAPRYRAWQKRALARAARFFVARATAAGIRADGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB46</accession>
    <name>A0A0S2DB46_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutaredoxin domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946006.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0400"/>
    <dbReference type="EnsemblBacteria" id="ALN55758">
        <property type="protein sequence ID" value="ALN55758"/>
        <property type="gene ID" value="GLE_0400"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0400"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.397"/>
    <dbReference type="OrthoDB" id="2056793at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097573">
        <property type="term" value="F:glutathione oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="PTHR10293"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="258"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="310" mass="33913" checksum="FC7DD3A49CEABC1D" modified="2016-02-17" version="1">MTLSADARQRIETLLRAHRLVVFMNATPDAPERFFSHKICHLLDGLGLDYAHVDVSRDAMLREQIKAYGGLQAIPQLYLDGKPLGDSDAVERMAGTDELHAALGLPAPDRTPPTVRLTAAAAEFLRGVVRGKGEGTVVDIEVDPQFRGSLRFGPRRKDAIAAEVDGVALQFDLASARRADGLSIDWQDVERGPSLLLSHPRAPVPKPVRWISPAEADARVRAGTLTVVDLRREDERALARLSLPFLSLDEGTHAIRNLPPQAPLAVLCHRGDRCWHGAQHLVQLGHRDVYAVEGGIDAWAADVDASIPRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB69</accession>
    <name>A0A0S2DB69_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0424</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946024.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55782">
        <property type="protein sequence ID" value="ALN55782"/>
        <property type="gene ID" value="GLE_0424"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0424"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.421"/>
    <dbReference type="OMA" id="GVWCRRY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="60" mass="6412" checksum="73354BEA3CCDE1C0" modified="2016-02-17" version="1">MTKSFVDEIGAERAQALASKAVAEAIAEADALGLPQVVKIDGVWCRRYPDGRVEPVEAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB74</accession>
    <name>A0A0S2DB74_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946028.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0430"/>
    <dbReference type="EnsemblBacteria" id="ALN55788">
        <property type="protein sequence ID" value="ALN55788"/>
        <property type="gene ID" value="GLE_0430"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0430"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.427"/>
    <dbReference type="OMA" id="YGHNRPD"/>
    <dbReference type="OrthoDB" id="1134706at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="487" mass="50159" checksum="0A2924DFB20C921D" modified="2016-02-17" version="1">MKAFKLVLWLALLTGAIWFAVVLAWQVNDVQPSGSALVLYLVGLPLLAIGAVLAVGYGLRRRKQRAQDAQADAATPAARASADDGEHASRAYALHLHATAVNLIVGASAEAAAAALVEPERPGLHPSLKDDNGLPVMAAQVNELDTDAVAEALQALAGGEAIEHVFAQEHLRAIALLEPVLEELLGLEAAIVAGAAPADASPALVAGRRSEAAAAPKSRLRTLILVADAWPQAARQRLGDWALAKAAALDLPEERIAVEVVPVEQAIDAWALIDRIGQRYRDEVTPDRHLLLACASQLSEGAVEALQAARRLIGHDRPEGLVPGEGAVGLWLSGPPEPGQPASPDALELRALQRGHVAAGTSSRNATRQTSELMARAIAATGQDADSVKAVVSDADQRPSRAIEIASAIAATCPELDPIGHNLSLGVACGHLGPVAPWAAIAVAAAQARSEGGPVLAIGLADGEARAALAVMPVPPPAPPAEPERAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBC5</accession>
    <name>A0A0S2DBC5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type VI secretion protein, VC_A0114 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Type VI secretion system baseplate subunit TssK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">tssK</name>
        <name evidence="2" type="ORF">FE772_02995</name>
        <name evidence="1" type="ORF">GLE_0444</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946040.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0444"/>
    <dbReference type="EnsemblBacteria" id="ALN55802">
        <property type="protein sequence ID" value="ALN55802"/>
        <property type="gene ID" value="GLE_0444"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0444"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.442"/>
    <dbReference type="OMA" id="LELKFWA"/>
    <dbReference type="OrthoDB" id="496911at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010263">
        <property type="entry name" value="T6SS_TssK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35566">
        <property type="entry name" value="PTHR35566"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05936">
        <property type="entry name" value="T6SS_VasE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03353">
        <property type="entry name" value="VI_chp_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="442" mass="48896" checksum="46D9A9C18D8C5E26" modified="2016-02-17" version="1">MSKIFWGEGLFLRPQHFQRQDAYHEGQVREMSSALHPYAWGLRQARFDVQSLASGTLRALQLSAIFPDGESYAAPGDDELPEAVSLADLPAGVQSTTIHLALPLLKEHGGNCAESSAAARFTQHNQVTLDLYTDAAEAELAYLRKSVRLLTDDEPRDPYVTVPVARVRRTPTGGFELDEAFMAPSISVSASAQLHAQLRRLLDSLQAKTDALYGLHREPSQHIIEFRSGDIASFWLLHTVNSSFAALSHLFRHPGLHPERLHQELSRLAGSLLTFSKIYGLGDLPAYSHADPEAGFERLFEMIRELLDTVISARYFQIALTEVKPSFHLGRLDSQRIDEKSVFYLGVAADIPGPELIQTVPVRFKVGAPDDVEKCVLSALPGVKLTHAGQVPAAIPVRPGSYYFAVEPRGPLYERMIKSQSLMIYVPAGVRDLKLELIALMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBH0</accession>
    <name>A0A0S2DBH0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TetR/AcrR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_03345</name>
        <name evidence="4" type="ORF">GLE_0525</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946096.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55883">
        <property type="protein sequence ID" value="ALN55883"/>
        <property type="gene ID" value="GLE_0525"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0525"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.520"/>
    <dbReference type="OMA" id="MFCAYLE"/>
    <dbReference type="OrthoDB" id="1309950at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040804">
        <property type="entry name" value="TetR_C_18"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17923">
        <property type="entry name" value="TetR_C_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="21"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN55883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW24850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="210" mass="23259" checksum="1D768EED39508463" modified="2016-02-17" version="1">MTDPKKPQISQRKQPKQARSSDSVAVILEAAAQVLAKEGAQRFTTARVAERAGVSVGSLYQYFPNKAAILFRLQTEEWGQTTALLCAILQDARKPPLRRLRELVHAFVRSECEEAAMRVALADAAPLYRDAPEARQAHSASERAFEAFMREALPRADDAARTVAGDLVITTLSQVGKEFSETPRTAQEIETYAQAMADMFCAYLRSVGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBL1</accession>
    <name>A0A0S2DBL1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC-transport substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0346</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0346"/>
    <dbReference type="EnsemblBacteria" id="ALN55704">
        <property type="protein sequence ID" value="ALN55704"/>
        <property type="gene ID" value="GLE_0346"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0346"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.343"/>
    <dbReference type="OMA" id="TMLDTMH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594722" evidence="1">
        <location>
            <begin position="29"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="2">
        <location>
            <begin position="77"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="545" mass="59703" checksum="8BEBADF649AC5D5D" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBL3</accession>
    <name>A0A0S2DBL3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">LysR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_15480</name>
        <name evidence="5" type="ORF">FE772_03555</name>
        <name evidence="3" type="ORF">GLE_0568</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000040">
        <property type="protein sequence ID" value="OPD63034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946131.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0568"/>
    <dbReference type="EnsemblBacteria" id="ALN55926">
        <property type="protein sequence ID" value="ALN55926"/>
        <property type="gene ID" value="GLE_0568"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63034">
        <property type="protein sequence ID" value="OPD63034"/>
        <property type="gene ID" value="BV903_15480"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0568"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.562"/>
    <dbReference type="OMA" id="GQAYYRH"/>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD63034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW24884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="306" mass="33427" checksum="7983B702619624F6" modified="2016-02-17" version="1">MTRLPDLEAWAIFAKVAELGSFARAAEELRLSQATVSKAVSRLETRLKTTLLHRTSRRISLTESGRGALERAGRILAEGEAVEAEVTAQARSPRGRVRLAAPMSFGVAHLAPLLPQFMQRYPEIALDIDFDDGVTDLVGGGYDLALRISALADSSLLARRLCGVRIVLVAAPAYLDARGRPTHPRELAGHSALAYAYSRFGNAWRFHHARHGDFSLSVPAPLRVNNAEALNPALLAGLGLALQPEFLVWRELRSGALEIVMPQWAPPPIALHVVTPPGRERPARVQALIEYLAQQFERAPWADPQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBQ0</accession>
    <name>A0A0S2DBQ0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0606</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946157.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55964">
        <property type="protein sequence ID" value="ALN55964"/>
        <property type="gene ID" value="GLE_0606"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0606"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.598"/>
    <dbReference type="OrthoDB" id="1469401at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="337" mass="35218" checksum="91C3084228AA9C62" modified="2016-02-17" version="1">MSIEPSSPAPRPASARRRLLLAAGIAAALAAIVAAYFAGRAGVGAGAARPDSHVRIAGESAAGSDAAAAAGALPTPIKGGVLPAPGAPLKDHFAQLQARANAGDAGAATRLVRDLDRCARLRSTQWRNAGATEDLTRRSTEGMSAAQLRTYQALLEAMELRQQAQRQDQATCAGVDEAMLASLVPNIAQAARLGDEQARACYLERGPLYDARSLIRHPDGLRAYRGTAAALVEAGLAAGDWRVVDLLQQAYEPGSKSLLAGLLGADPLQHYRYLKLYRLGAEAHRADQLDRQLAAVATGLSPAQLAQGDAWAQNTLDAGFQGRSTDGTPPGWEACDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBX9</accession>
    <name>A0A0S2DBX9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12">ATP synthase subunit a</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP synthase F0 sector subunit a</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">F-ATPase subunit 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 13" type="primary">atpB</name>
        <name evidence="14" type="ORF">BV903_08390</name>
        <name evidence="15" type="ORF">FE772_04100</name>
        <name evidence="13" type="ORF">GLE_0683</name>
    </gene>
    <organism evidence="13 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">C3</strain>
        </source>
    </reference>
    <reference evidence="14 17" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">B25</strain>
        </source>
    </reference>
    <reference evidence="15 18" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 18">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11 12">Cell membrane</location>
            <topology evidence="11 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11 12">Belongs to the ATPase A chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000017">
        <property type="protein sequence ID" value="OPD64455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949941.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000017.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0683"/>
    <dbReference type="EnsemblBacteria" id="ALN56041">
        <property type="protein sequence ID" value="ALN56041"/>
        <property type="gene ID" value="GLE_0683"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64455">
        <property type="protein sequence ID" value="OPD64455"/>
        <property type="gene ID" value="BV903_08390"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0683"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.671"/>
    <dbReference type="OMA" id="FTHAVRL"/>
    <dbReference type="OrthoDB" id="867266at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01393">
        <property type="entry name" value="ATP_synth_a_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045082">
        <property type="entry name" value="ATP_syn_F0_a_bact/chloroplast"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000568">
        <property type="entry name" value="ATP_synth_F0_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023011">
        <property type="entry name" value="ATP_synth_F0_asu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035908">
        <property type="entry name" value="F0_ATP_A_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42823">
        <property type="entry name" value="PTHR42823"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00119">
        <property type="entry name" value="ATP-synt_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81336">
        <property type="entry name" value="SSF81336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01131">
        <property type="entry name" value="ATP_synt_6_or_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00449">
        <property type="entry name" value="ATPASE_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 11 12" id="KW-0138">CF(0)</keyword>
    <keyword evidence="6 11 12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="247"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN56041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OPD64455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW24974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="276" mass="29925" checksum="96EBA1AF6D7F42C5" modified="2016-02-17" version="1">MSEQTGSGGLNEYIQHHLQQNTISLGGGAFHIDTWVVSLILGLVFITWFGFFARKASSGVPSKGQAFVELILEFIDGQVKDSFHGDRSSLTPLALTIFVWVVLMNGMDLLPLDLPGWVVKTTAGAEVAHHTYFRWVPTADLNTTLALSTTVFFLILYHSVKAKGGLGFGKELLTAPFHAHSTGAKIALAPANLGLNVIEYLVKPVSLAMRLFGNMYGGELVFMLIAGLLGGGLLMFVPGVIFNAAWALFHILIVLLQAFIFMILTVVYIAGAYESH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC39</accession>
    <name>A0A0S2DC39_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA polymerase sigma factor, sigma-70 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_0731</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0731"/>
    <dbReference type="EnsemblBacteria" id="ALN56089">
        <property type="protein sequence ID" value="ALN56089"/>
        <property type="gene ID" value="GLE_0731"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0731"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.719"/>
    <dbReference type="OMA" id="CEPATIF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="3">
        <location>
            <begin position="86"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="4">
        <location>
            <begin position="185"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="251" mass="27889" checksum="836A4F98C3378E8A" modified="2016-02-17" version="1">MANRYTSVFQLGLNEAGMGQIAMAPVTGAQDRSGFEMGFVRPAAEAGLVSKQITGAWAKVDVGEESSAANQPATAQQDGDHFVGFLRDNREALIAFLRKSAASHEDAQDIAQETMMRMLRYRDQPADALKILMYRIAINALNDRGRRQKTRHAPEHVSLDEDYHALPSPEPSHDQRVATEQELALVRTAIMQLPVRSRQIYLLNRINGMSYTQIAKHCGISVKAVEKNIGRALALLRARMKESGYETLQEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCB6</accession>
    <name>A0A0S2DCB6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter, ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_0655</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0655"/>
    <dbReference type="EnsemblBacteria" id="ALN56013">
        <property type="protein sequence ID" value="ALN56013"/>
        <property type="gene ID" value="GLE_0655"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0655"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.644"/>
    <dbReference type="OMA" id="FARAIMS"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042953">
        <property type="term" value="P:lipoprotein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015854">
        <property type="entry name" value="ABC_transpr_LolD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24220:SF654">
        <property type="entry name" value="PTHR24220:SF654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="36"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="72"/>
            <end position="79"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN56013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="254" mass="26861" checksum="DF185F3ADFC93AFB" modified="2016-02-17" version="1">MAVSDLAAPIMADELAQNDERAQTGRSPDPARPITLDVRGLGKRVSLPSGELTILDGVGFSIAKGDTVAIVGASGSGKSTLLSLLAGLDSPSAGSVELDGETISALDEDGRARVRGEKVGFVFQSFQLLPSLTALENVMLPLELRGDRDAQAPARAILDKVGLGQRLDHYPRQLSGGEQQRVALARAFVTRPSLLFADEPTGNLDTHTGQAIVELLFQLNADAGTTLILVTHDDHLAARCHRCIRLDSGRLVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCP1</accession>
    <name>A0A0S2DCP1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamate-1-semialdehyde 2,1-aminomutase</fullName>
            <shortName evidence="7">GSA</shortName>
            <ecNumber evidence="7">5.4.3.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glutamate-1-semialdehyde aminotransferase</fullName>
            <shortName evidence="7">GSA-AT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">hemL</name>
        <name evidence="10" type="ORF">FE772_05015</name>
        <name evidence="9" type="ORF">GLE_0873</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(S)-4-amino-5-oxopentanoate = 5-aminolevulinate</text>
            <dbReference type="Rhea" id="RHEA:14265"/>
            <dbReference type="ChEBI" id="CHEBI:57501"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="5.4.3.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.3.8" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946361.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0873"/>
    <dbReference type="EnsemblBacteria" id="ALN56231">
        <property type="protein sequence ID" value="ALN56231"/>
        <property type="gene ID" value="GLE_0873"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0873"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.862"/>
    <dbReference type="OMA" id="WGPLIFG"/>
    <dbReference type="OrthoDB" id="493793at2"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00317"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042286">
        <property type="term" value="F:glutamate-1-semialdehyde 2,1-aminomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00375">
        <property type="entry name" value="HemL_aminotrans_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004639">
        <property type="entry name" value="4pyrrol_synth_GluAld_NH2Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00713">
        <property type="entry name" value="hemL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="4 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW25126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="427" mass="44929" checksum="34EB021BD2A8D285" modified="2016-02-17" version="1">MNNARSHELFTRASQLLPGGVNSPVRAFKSVGGEPFFAQRAEGAYLIDVDGNRYVDYVGSWGPMIAGHAHPQVLAAVERAMRDGLSFGVPNALEVAMAEEIVKIVPSCAMVRMVNSGTEATLSAIRVARGATGRNRIVKFEGCYHGHGDSFLVKAGSGVMTLGLPNSPGVPSALADLTLTLAYNDFDAATKLFDEVGGEIAGLIIEPIVGNANCILPRDGYLQHLRALCTQHGALLIFDEVMTGFRVALGGAQALYGIEPDLSTFGKIIGGGMPVGAYGGRRELMSQVAPAGPIYQAGTLSGNPVAMAAGLATLELIQAPGFHAELERRTHTLCDGLEAAAREAGVAFHTTRAPGMFGLYFREGPVETFDDAKASDAAKFNRFFHAMLERGVYLAPSAFEAGFVSSAHGEAEIAQTLEAARAAFAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCQ3</accession>
    <name>A0A0S2DCQ3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">4-hydroxybutyrate coenzyme A transferase</fullName>
            <ecNumber evidence="2">2.8.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cat2</name>
        <name evidence="2" type="ORF">GLE_0950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.8.3.-" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0950"/>
    <dbReference type="EnsemblBacteria" id="ALN56308">
        <property type="protein sequence ID" value="ALN56308"/>
        <property type="gene ID" value="GLE_0950"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0950"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.937"/>
    <dbReference type="OMA" id="CSEMFVN"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1080.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026888">
        <property type="entry name" value="AcetylCoA_hyd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038460">
        <property type="entry name" value="AcetylCoA_hyd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13336">
        <property type="entry name" value="AcetylCoA_hyd_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AcetylCoA_hyd_C" evidence="1">
        <location>
            <begin position="420"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="701" mass="75893" checksum="FB2CAF78CD677193" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCR3</accession>
    <name>A0A0S2DCR3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Endonuclease S1</fullName>
            <ecNumber evidence="7">3.1.30.1</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="8">S1/P1 nuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_05430</name>
        <name evidence="7" type="ORF">GLE_0960</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.30.1" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946424.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0960"/>
    <dbReference type="EnsemblBacteria" id="ALN56318">
        <property type="protein sequence ID" value="ALN56318"/>
        <property type="gene ID" value="GLE_0960"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0960"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.947"/>
    <dbReference type="OMA" id="GYRLANW"/>
    <dbReference type="OrthoDB" id="1079090at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11010">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.575.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008947">
        <property type="entry name" value="PLipase_C/P1_nuclease_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003154">
        <property type="entry name" value="S1/P1nuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146">
        <property type="entry name" value="PTHR33146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02265">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48537">
        <property type="entry name" value="SSF48537"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726644" evidence="6">
        <location>
            <begin position="28"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN56318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW25182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="280" mass="30155" checksum="91CD52011C2339C0" modified="2016-02-17" version="1">MTAPHTSARRLLAAAALVLALPLPALAWGPQGHRLVAELAWNDMSPAARAEAEKLLAGEPDPTLPGIANWADQLRAEDPDLGKRSAKWHYVNLGESDCRYDAARDCPGGNCVVAAIAAQSAILADRRKPRAERLQALKFVVHLVGDVHQPLHAGYARDKGGNDFQLAIPGQPERPGGYGANLHSLWDSRMLSMSKLGDDKYLARLEKIQVPAVSALALPPPAADWAEDSCKLVLQPGFYPPTHKLAPDYVATWRPLAETQLRLGGEHLAKLLDAALAPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCZ5</accession>
    <name>A0A0S2DCZ5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TetR/AcrR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_05780</name>
        <name evidence="3" type="ORF">GLE_1038</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946480.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1038"/>
    <dbReference type="EnsemblBacteria" id="ALN56396">
        <property type="protein sequence ID" value="ALN56396"/>
        <property type="gene ID" value="GLE_1038"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1038"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1026"/>
    <dbReference type="OMA" id="CAQTIYT"/>
    <dbReference type="OrthoDB" id="2047542at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011075">
        <property type="entry name" value="TetR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16925">
        <property type="entry name" value="TetR_C_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="8"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="200" mass="21739" checksum="C592A6394A3B4ADA" modified="2016-02-17" version="1">MNAIPVPHDVRKHILDVAYPLMLRKGFTAVGLAEVLSAAQVPKGSFYHYFGSKEAFGEALLEAYFSDYLQHVDALMAQPGSGAQRAIAYFEDWREAQTGSDPDGRCLVVKLGAEVCDLSEPMRAALERGTGAVIARIARCIERGRDDGSLPAGPEPQSLAQGLYQNWIGASLLAKVQREREPMDLAMAGTRHLLGLPTQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD75</accession>
    <name>A0A0S2DD75_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1077</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56435">
        <property type="protein sequence ID" value="ALN56435"/>
        <property type="gene ID" value="GLE_1077"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1077"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="205" mass="22458" checksum="E42DCFFE742BCD6E" modified="2016-02-17" version="1">MRARVRRRARSVRDDLYRQEKFPSADAADFASHKPECAKVRELFFPATGVGKVGGDDRRVRDRHARTRRCGRATRGRRRQRRAAIAASPPRAQRAARAPVARERHGGVAASAAAATRRSVRNATRKWSARGRTCVASSDPAASIGAAGGDAARARSGLGTRTSAAGALHRDRGVRPPRRPRRHATASAVVWIFPSENDACAWRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDA7</accession>
    <name>A0A0S2DDA7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1166</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56524">
        <property type="protein sequence ID" value="ALN56524"/>
        <property type="gene ID" value="GLE_1166"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1166"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1151"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="53" mass="6136" checksum="E5AC6F36B15FE348" modified="2016-02-17" version="1">MNLSFPGYANDKCRALVYLELQRGDLSAEDVFVEMVLKRDKWIVVGRRIVYAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDB5</accession>
    <name>A0A0S2DDB5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Arabinose 5-phosphate isomerase</fullName>
            <shortName evidence="2">API</shortName>
            <ecNumber evidence="2">5.3.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BV903_16415</name>
        <name evidence="11" type="ORF">D9T17_21140</name>
        <name evidence="10" type="ORF">FE772_06505</name>
        <name evidence="8" type="ORF">GLE_1197</name>
    </gene>
    <organism evidence="8 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 12">C3</strain>
        </source>
    </reference>
    <reference evidence="9 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">OH11</strain>
        </source>
    </reference>
    <reference evidence="10 15" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 15">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>D-arabinose 5-phosphate = D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23104"/>
            <dbReference type="ChEBI" id="CHEBI:57693"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="EC" id="5.3.1.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the SIS family. GutQ/KpsF subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.13" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000043">
        <property type="protein sequence ID" value="OPD62862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000053">
        <property type="protein sequence ID" value="ROU04947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946591.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000053.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1197"/>
    <dbReference type="EnsemblBacteria" id="ALN56555">
        <property type="protein sequence ID" value="ALN56555"/>
        <property type="gene ID" value="GLE_1197"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62862">
        <property type="protein sequence ID" value="OPD62862"/>
        <property type="gene ID" value="BV903_16415"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1197"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1182"/>
    <dbReference type="OMA" id="LMACLMR"/>
    <dbReference type="OrthoDB" id="571638at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019146">
        <property type="term" value="F:arabinose-5-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05014">
        <property type="entry name" value="SIS_Kpsf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004800">
        <property type="entry name" value="KdsD/KpsF-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035474">
        <property type="entry name" value="SIS_Kpsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004692">
        <property type="entry name" value="KdsD_KpsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00393">
        <property type="entry name" value="kpsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0129">CBS domain</keyword>
    <keyword evidence="2 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="SIS" evidence="7">
        <location>
            <begin position="51"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="220"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="288"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="site" description="Catalytically relevant" evidence="4">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <feature type="site" description="Catalytically relevant" evidence="4">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <feature type="site" description="Catalytically relevant" evidence="4">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <feature type="site" description="Catalytically relevant" evidence="4">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR004692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR004692-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR004692-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN56555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD62862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW25364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROU04947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="340" mass="35518" checksum="5D2C97707DF8ECCA" modified="2016-02-17" version="1">MTQPAPARDPRTTIPAGSEAGLADSGRRVFAIEAQALAAVAARIDGDFTAACKRILAASGRVVCTGMGKSGHIARKIAATLASTGTPAFYVHPGEAGHGDLGMITDADVVLALSYSGESDEVLMLLPVLKRQGNTVIAMTGRPQSTLARESDVHLDVSVPAEACPLDLAPTSSTTASLAMGDALAVALLEARGFTADDFARSHPAGALGRRLLLHITDIMHAGDDVPRVGADASVSQALVEMSHKRLGMTAVVDDDGRLIGLYTDGDLRRTLDDRGVDLRSTRIAEVMTRAPKTIGADALAVEAAQLMETHKISGLLVVDTERRVVGALNIHDLLRARVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDK2</accession>
    <name>A0A0S2DDK2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transporter, small conductance mechanosensitive ion channel (MscS) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_1279</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946653.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1279"/>
    <dbReference type="EnsemblBacteria" id="ALN56636">
        <property type="protein sequence ID" value="ALN56636"/>
        <property type="gene ID" value="GLE_1279"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1279"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1262"/>
    <dbReference type="OMA" id="PDCEIDS"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="63"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN56636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="418" mass="44761" checksum="36E229D8BC51897E" modified="2016-02-17" version="1">MSAAPKPPPLDRDPELAEVVSDAMDVVSNPTDLLITLLALTLAAAVGVLVTRALKQRIGHQRPVLLTVVEYLCTPVLTLLTLGVLSLFGGSFGNPLIGLAATLLLLFLVIRFFGMTVELLFRPTLPLKIMLRAVTVVAWLALVVGVFVDRSQPLAKLYGASFKFGGINVSSQGLVAGLIGGVVIAIVALWGDKTVTKLLRRSRTLQPNYILALSRIFSVAIWIAATLAIFAASDINITALAAFGGALGIGLGLGLQKLAASYISGLIVLFEQSVRVGDNIVSNSVSGRVTRMTVRYTMIRTRDGVEAIVPNDLLTNNVIVNQSWSDRNLRLVCGVLVKGDTDLELARTLFVEAMNAQPRVLQEPSPHMYITGVNDKGIQLDGHFWISDPENGQNNVASDIYDAVLGAFRKNGVQLVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDT3</accession>
    <name>A0A0S2DDT3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, MarR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1352</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1352"/>
    <dbReference type="EnsemblBacteria" id="ALN56709">
        <property type="protein sequence ID" value="ALN56709"/>
        <property type="gene ID" value="GLE_1352"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1352"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1334"/>
    <dbReference type="OMA" id="GVSRHYD"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="131" mass="14262" checksum="ACC0BECCC944503E" modified="2016-02-17" version="1">MRKLSRLMSQRYDQALAPAGLNLNQYSILRRTGGRGRPLGEIAHELGMDRSTLSRDLKPLAAAGWIESAPGEDARQRLLRVTAAGRAAVERAMPLWRRAQDEIDEGLGADGIAALHAQLDRAIAQLQGEAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDV8</accession>
    <name>A0A0S2DDV8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_1299</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1299"/>
    <dbReference type="EnsemblBacteria" id="ALN56656">
        <property type="protein sequence ID" value="ALN56656"/>
        <property type="gene ID" value="GLE_1299"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1299"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1282"/>
    <dbReference type="OMA" id="PWTDPQF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="38"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="421"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN56656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="967" mass="104287" checksum="68690CF658779B27" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE03</accession>
    <name>A0A0S2DE03_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sulfite reductase [NADPH] hemoprotein beta-component</fullName>
            <shortName evidence="9">SiR-HP</shortName>
            <shortName evidence="9">SiRHP</shortName>
            <ecNumber evidence="9">1.8.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 12" type="primary">cysI</name>
        <name evidence="13" type="ORF">FE772_06675</name>
        <name evidence="12" type="ORF">GLE_1234</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">C3</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>3 H2O + hydrogen sulfide + 3 NADP(+) = 4 H(+) + 3 NADPH + sulfite</text>
            <dbReference type="Rhea" id="RHEA:13801"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="9">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>siroheme</name>
            <dbReference type="ChEBI" id="CHEBI:60052"/>
        </cofactor>
        <text evidence="9">Binds 1 siroheme per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Sulfur metabolism; hydrogen sulfide biosynthesis; hydrogen sulfide from sulfite (NADPH route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.2" evidence="9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946618.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1234"/>
    <dbReference type="EnsemblBacteria" id="ALN56591">
        <property type="protein sequence ID" value="ALN56591"/>
        <property type="gene ID" value="GLE_1234"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1234"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1218"/>
    <dbReference type="OMA" id="MGMTHGD"/>
    <dbReference type="OrthoDB" id="1588103at2"/>
    <dbReference type="UniPathway" id="UPA00140">
        <property type="reaction ID" value="UER00207"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009337">
        <property type="term" value="C:sulfite reductase complex (NADPH)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004783">
        <property type="term" value="F:sulfite reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019344">
        <property type="term" value="P:cysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070814">
        <property type="term" value="P:hydrogen sulfide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01540">
        <property type="entry name" value="CysI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011786">
        <property type="entry name" value="CysI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005117">
        <property type="entry name" value="NiRdtase/SiRdtase_haem-b_fer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036136">
        <property type="entry name" value="Nit/Sulf_reduc_fer-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006067">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045169">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006066">
        <property type="entry name" value="NO2/SO3_Rdtase_FeS/sirohaem_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11493">
        <property type="entry name" value="PTHR11493"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01077">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03460">
        <property type="entry name" value="NIR_SIR_ferr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00397">
        <property type="entry name" value="SIROHAEM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55124">
        <property type="entry name" value="SSF55124"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="SSF56014"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02041">
        <property type="entry name" value="CysI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00365">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="2 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="3 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
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        <location>
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            <end position="545"/>
        </location>
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        <location>
            <position position="435"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="441"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
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    <feature type="binding site" evidence="9">
        <location>
            <position position="480"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
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    <feature type="binding site" evidence="9">
        <location>
            <position position="484"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="484"/>
        </location>
        <ligand>
            <name>siroheme</name>
            <dbReference type="ChEBI" id="CHEBI:60052"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
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        <source>
            <dbReference type="Pfam" id="PF03460"/>
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        <source>
            <dbReference type="EMBL" id="ALN56591.1"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW25392.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
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    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
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    <sequence length="579" mass="63198" checksum="94644B2DBF782D58" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE44</accession>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        <text evidence="6">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
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    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
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    </evidence>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN56639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW25432.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
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    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="687" mass="74202" checksum="95FED02743ADDE1B" modified="2016-02-17" version="1"> </sequence>
</entry>
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    <name>A0A0S2DE55_LYSEN</name>
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            <fullName evidence="3">DUF882 domain-containing protein</fullName>
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        <submittedName>
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        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">FE772_07885</name>
        <name evidence="2" type="ORF">GLE_1503</name>
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        </lineage>
    </organism>
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            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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    <dbReference type="EnsemblBacteria" id="ALN56860">
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="95"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="210" mass="22638" checksum="5CF814304AE447FD" modified="2016-02-17" version="1">MRAPAGVSTLIKTSLAASLLAGCAADTPEQRFERWRGDGREAQVRAYADHLARHGVAAVAPLSQQLRSGRNWRWCGADEFALPPRASWPRSVATLRLLAELRAAGLIDGARIVSGYRAPEFNRCEGGSRQSRHMAGGAYDLELAADTDGARLCAFWRRRGLATGFGLGFYDRRRLHVDTAGLRTWGGDYTRKTSPCLRPGAVGAGSGAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE89</accession>
    <name>A0A0S2DE89_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF2065 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_21795</name>
        <name evidence="4" type="ORF">FE772_07940</name>
        <name evidence="2" type="ORF">GLE_1514</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 7">YC36</strain>
        </source>
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            <begin position="42"/>
            <end position="60"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61810.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25606.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
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    </evidence>
    <sequence length="63" mass="6829" checksum="AC47796466D5743A" modified="2016-02-17" version="1">MAGEVWRALCLVVVLEGLMLFVAPGGWKRAAEQLRSLPDPHLRAVGGIMVVMALTGLWCLRLG</sequence>
</entry>
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    <accession>A0A0S2DEC3</accession>
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        </submittedName>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </evidence>
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    </evidence>
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        </source>
    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
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    </evidence>
    <sequence length="143" mass="15383" checksum="84B21003E65A74E2" modified="2016-02-17" version="1">MAARPFRLLQLDHVVLRVRDTAAMVAFYCEVLGCSVERRQDEIGLVQLRAGDSLIDLVDVEGKIGRLGGAAPGEQGRNMDHLCLRAEPFNRDAIAAHLAAHGARIGEFGSRYGAEGEGPSQYLYDPEGNMVELKGPPDAPVAA</sequence>
</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 5" key="2">
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
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        </source>
    </evidence>
    <sequence length="130" mass="13808" checksum="C4583C64AD05970F" modified="2016-02-17" version="1">MNATLVKWSLTAALALAALPALAAEPLPACKDLPQNVRTMIRDFDACARTADPAKACLRFKLNARAYDNAQGLLPPLGGIGAQYWRASPALLGSPQGLVYNLAVGAKGKPISKRYYTGDNFKAFCEIAGK</sequence>
</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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        </location>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25670.1"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
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        </source>
    </evidence>
    <sequence length="266" mass="30129" checksum="494AF3F55614F81F" modified="2016-02-17" version="1">MSTPVTWAIQTNFIADEQIRRVWSAAEDAGARVQDVLVVPFSDELGNEVPPLDGVVIPYGATKLTRLAQKRGWRGLCFDEAAFRVDAWNRHRDDMLNQHVRQMSVRECMAAMQDEDEESRWFVRPVQDLKHFDGTVTVAREIRRWMSSVDSGNYSFDGDTEVIVAPVQKLHGEWRFFVVDGQVVDGSSYRIAGQRLANAVARPELYETAQSLADGWLPHRTCVMDVALTDEGYKVIEFNTFNSSGFYAHDIEKIVAAVTRHFATQA</sequence>
</entry>
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    <accession>A0A0S2DEF7</accession>
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        <name evidence="5" type="ORF">D9T17_19810</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">ATCC 29487</strain>
        </source>
    </reference>
    <reference evidence="3 9" key="3">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 9">B25</strain>
        </source>
    </reference>
    <reference evidence="5 10" key="4">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 10">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 11" key="5">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homohexamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Hfq family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000072">
        <property type="protein sequence ID" value="OPD61806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000047">
        <property type="protein sequence ID" value="ROU05369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNOG01000002">
        <property type="protein sequence ID" value="SDW53512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946835.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000047.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1510"/>
    <dbReference type="EnsemblBacteria" id="ALN56867">
        <property type="protein sequence ID" value="ALN56867"/>
        <property type="gene ID" value="GLE_1510"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61806">
        <property type="protein sequence ID" value="OPD61806"/>
        <property type="gene ID" value="BV903_21775"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDW53512">
        <property type="protein sequence ID" value="SDW53512"/>
        <property type="gene ID" value="SAMN05421681_102134"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1510"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1491"/>
    <dbReference type="OMA" id="QQMVYKH"/>
    <dbReference type="OrthoDB" id="1989988at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000183696">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01716">
        <property type="entry name" value="Hfq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00436">
        <property type="entry name" value="Hfq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005001">
        <property type="entry name" value="Hfq"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34772">
        <property type="entry name" value="PTHR34772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17209">
        <property type="entry name" value="Hfq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02383">
        <property type="entry name" value="Hfq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0346">Stress response</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU05369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="SDW53512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000183696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="90" mass="9795" checksum="7CDD5926F2C8E332" modified="2016-02-17" version="1">MSKGQSLQDPFLNALRRERVPVSVYLVNGIKLQGTIESFDQFVVLLRNTVSQMVYKHAISTVVPARNVRVGPGGGYVQSADGSDGSDENE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEG1</accession>
    <name>A0A0S2DEG1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Bcr/CflA family efflux transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FE772_08105</name>
        <name evidence="9" type="ORF">GLE_1549</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the major facilitator superfamily. Bcr/CmlA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946869.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1549"/>
    <dbReference type="EnsemblBacteria" id="ALN56906">
        <property type="protein sequence ID" value="ALN56906"/>
        <property type="gene ID" value="GLE_1549"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1549"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1531"/>
    <dbReference type="OMA" id="FNIICVV"/>
    <dbReference type="OrthoDB" id="1452500at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004812">
        <property type="entry name" value="Efflux_drug-R_Bcr/CmlA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00710">
        <property type="entry name" value="efflux_Bcr_CflA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="312"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="376"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="8">
        <location>
            <begin position="15"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW25636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="420" mass="44901" checksum="46E6F9520EDD08EB" modified="2016-02-17" version="1">MSADAAKTPIPIRRLALLLGGLAMFGPFSIDTIFPAFPAMGAQLGADKLQMQQTISVYLVAYALMSIVHGPLSDAIGRRKVILGGLAVFTLASAACALATDLPTLLFFRAVQGLSAGVGLIVGRAVIRDLLHGDDAQRLMSQVMMIFGIAPAIAPVIGGWILGWSHWPAIFWFLVAFSVVLWAAVALLLPETHPPQARLALKPKRLMRDYVAIFLNPRFQRLTAVGAFNFGALFLYIASAPAFVLDILKLGERDFAWFFVPTIGGMVAGSFVSGRAAGKVSGDRLVDIGFACCALAIALNLGYNLWTDAPRVPWAVAPMCIGAFGIALVFPIVTLSILDMYPHQRGSASSLQAFAGLVVNALLAGVISPLLSDRALHLAVAASGLTAVGWLFWRWEAWVSRNRVARVPEDAVVIEPQDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEK4</accession>
    <name>A0A0S2DEK4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase, GNAT family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_07305</name>
        <name evidence="2" type="ORF">GLE_1378</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946730.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1378"/>
    <dbReference type="EnsemblBacteria" id="ALN56735">
        <property type="protein sequence ID" value="ALN56735"/>
        <property type="gene ID" value="GLE_1378"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1378"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1360"/>
    <dbReference type="OMA" id="LYVQPRH"/>
    <dbReference type="OrthoDB" id="1526822at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="27"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="180" mass="18992" checksum="DAF148F74FA4890A" modified="2016-02-17" version="1">MTDPATVPSIRRAHAGDADALALAGAATFLDTFAGILDGADIVAHCRKQHAAELYAQALADPATALWLAESALGAAPVGFAMLTAPNLPLADLRADDLELKRIYLLSRFHGGGTGRRLMQHAIDEARARGAGRLLLGVYAGNERALAFYARCGYAQIGEREFQVGGHTYHDAILALELAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEW5</accession>
    <name>A0A0S2DEW5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Dihydroorotate dehydrogenase (quinone)</fullName>
            <ecNumber evidence="11">1.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">DHOdehase</fullName>
            <shortName evidence="11">DHOD</shortName>
            <shortName evidence="11">DHODase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Dihydroorotate oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 13" type="primary">pyrD</name>
        <name evidence="14" type="ORF">BV903_13475</name>
        <name evidence="15" type="ORF">FE772_09050</name>
        <name evidence="13" type="ORF">GLE_1758</name>
    </gene>
    <organism evidence="13 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">C3</strain>
        </source>
    </reference>
    <reference evidence="14 17" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">B25</strain>
        </source>
    </reference>
    <reference evidence="15 18" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 18">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 11">Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>(S)-dihydroorotate + a quinone = a quinol + orotate</text>
            <dbReference type="Rhea" id="RHEA:30187"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:30864"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="11">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 11">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; orotate from (S)-dihydroorotate (quinone route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 11">Cell membrane</location>
            <topology evidence="3 11">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 11">Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.2" evidence="11"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000034">
        <property type="protein sequence ID" value="OPD63434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947029.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1758"/>
    <dbReference type="EnsemblBacteria" id="ALN57113">
        <property type="protein sequence ID" value="ALN57113"/>
        <property type="gene ID" value="GLE_1758"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63434">
        <property type="protein sequence ID" value="OPD63434"/>
        <property type="gene ID" value="BV903_13475"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1758"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1734"/>
    <dbReference type="OMA" id="ERIKMGA"/>
    <dbReference type="OrthoDB" id="1109542at2"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00946"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004152">
        <property type="term" value="F:dihydroorotate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04738">
        <property type="entry name" value="DHOD_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00225">
        <property type="entry name" value="DHO_dh_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012135">
        <property type="entry name" value="Dihydroorotate_DH_1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005719">
        <property type="entry name" value="Dihydroorotate_DH_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001295">
        <property type="entry name" value="Dihydroorotate_DH_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000164">
        <property type="entry name" value="DHO_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01036">
        <property type="entry name" value="pyrD_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00911">
        <property type="entry name" value="DHODEHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00912">
        <property type="entry name" value="DHODEHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 11" id="KW-0288">FMN</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 11 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8 11" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHO_dh" evidence="12">
        <location>
            <begin position="44"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="11">
        <location>
            <begin position="110"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="11">
        <location>
            <begin position="247"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="61"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="319"/>
            <end position="320"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN57113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OPD63434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW25791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="353" mass="37786" checksum="50C891543E71FAA4" modified="2016-02-17" version="1">MYSLARPFLFGLDAERAHGLGLSALETAYRSGLNPLVARAPKPLPTKVLGLSFPNPVGLAAGLDKNGAHIDALLALGFGFVEIGTVTPRAQQGNPRPRMFRLPEQQAVINRLGFNNEGVDALVRNVSKARRRGGGLLGINIGKNKDTPNDQAERDYLHCLERVYPLADYITVNISSPNTAGLRELQEEQSLRRLIGNLREAQETFAAREGRRVPMLVKIAPDLSDDDIEAASRVLAELRVDGVIATNTTVAREGVEGSAHAGEAGGLSGRPLMAQATAVLRRMRTRLPEHIPMVGVGGILSGADAVTKMAAGASLVQVYSGLVYRGPALIGECVDAIRRRKEAPSRGHVPPQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF47</accession>
    <name>A0A0S2DF47_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">3-dehydroquinate dehydratase</fullName>
            <ecNumber evidence="5">4.2.1.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_1908</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3-dehydroquinate = 3-dehydroshikimate + H2O</text>
            <dbReference type="Rhea" id="RHEA:21096"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="EC" id="4.2.1.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 3/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homododecamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the type-II 3-dehydroquinase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.10" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947135.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1908"/>
    <dbReference type="EnsemblBacteria" id="ALN57259">
        <property type="protein sequence ID" value="ALN57259"/>
        <property type="gene ID" value="GLE_1908"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1908"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1876"/>
    <dbReference type="OMA" id="PYVEAHD"/>
    <dbReference type="OrthoDB" id="1444664at2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00086"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003855">
        <property type="term" value="F:3-dehydroquinate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.9100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001874">
        <property type="entry name" value="DHquinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036441">
        <property type="entry name" value="DHquinase_II_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01220">
        <property type="entry name" value="DHquinase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52304">
        <property type="entry name" value="SSF52304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="150" mass="15794" checksum="2E71A149A8DB815A" modified="2016-02-17" version="1">MSILILRGPHTDAAVDSMIPPLAGEVRATLVERAAGAGKALALRSCRSESELVECLRNMRAANAELLLLDPGACLPASAELRGALEQLTVPYIEVHDDDTNALEPSLAPGCGRRLRLVHGYSAQSYTLALSIALEHLGCAESGNDIHVGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF63</accession>
    <name>A0A0S2DF63_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF58 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1682</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1682"/>
    <dbReference type="EnsemblBacteria" id="ALN57038">
        <property type="protein sequence ID" value="ALN57038"/>
        <property type="gene ID" value="GLE_1682"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1682"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1660"/>
    <dbReference type="OMA" id="TAETRFP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="DUF58" evidence="2">
        <location>
            <begin position="229"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="336" mass="36736" checksum="8453C10AB187C877" modified="2016-02-17" version="1">MSAAPARADAAPAPAARSLWRRGRARMHAWTRPRLPEALPVQFDRRRIYVLPTGFGAFYGALLTAMILGALNYNNNPAFLLALLLGGAGLASLIAAQLQLAGLRIVAVDAEPVPAGSAMRVRVHARAAPDRPRQGLQVDDGLAGELEPARLDLEQGAGEAELRIATHRRGWFDLPKLRVSTTRPLGLARAWSHVWPEAPLLVYPAPEAHGPPLPVGGGDPTVTRLHPSGDDVHHLRNYRPGDARRAIAWKHSARRDTLLVREYEQPLGADVELDWHRLHGLPQETRISRLARWVDEAERDGCRYRLTLPGHNPLGPGNGAAHRHACLRALALMPHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF99</accession>
    <name>A0A0S2DF99_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1819</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1819"/>
    <dbReference type="EnsemblBacteria" id="ALN57171">
        <property type="protein sequence ID" value="ALN57171"/>
        <property type="gene ID" value="GLE_1819"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1819"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1790"/>
    <dbReference type="OMA" id="AWWGEEL"/>
    <dbReference type="OrthoDB" id="1449625at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="272" mass="29481" checksum="AB798DB5A6BB50C6" modified="2016-02-17" version="1">MKAAMNAPAAEDPPHQHPAQGQPAPGQPVQGQPVQEQALQDFAGKWRARWPEWSVAEVFVPRAQRGVAVAWAALQQELTDAAWGGTDALPGEAKLGWWMEELQGWRQGRRRHPLGLALQRQDAPWAALAASLPGLRDSRERPGDRGEAFDGLLPLAQACAAIDVSLFDPVPGQLPETAVPAIQSSLLEARLVLQGDAAVPLSVVARAMARPGEGAAVEWSRELLAQWPERFGATVPRRLWTALAHTRLQRGDAARPLSPWTALLAAWRGARN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFC1</accession>
    <name>A0A0S2DFC1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_09525</name>
        <name evidence="1" type="ORF">GLE_1858</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947101.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57210">
        <property type="protein sequence ID" value="ALN57210"/>
        <property type="gene ID" value="GLE_1858"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1858"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1829"/>
    <dbReference type="OrthoDB" id="2110619at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="272" mass="29372" checksum="F0DAE9F2AF257D46" modified="2016-02-17" version="1">MSLPDCQYSHITWLNTQSAAYQALTEGLKSPSAAPGAVVHFLETLTAAHQDFKRGLGPGADTMALLKAYQDKTGIVSTRDYTLPDIPNNPNDPGNSFAIDLIEGIAGAAETEIGIGISLYTLVLDLIELFDIKLHLQGVLFNTANTDLDHVQFRFGPNGQPNVLPLATTIPAAKTIMNPVDKKNYPCVGFALFGGVGYESLEGFYIAMQAYRKHGAPIQAYCQFYASDRGIAPGIDDRNHAPLRDVCYTPEFVGVMSEQRSTPNGIVAIFCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFG8</accession>
    <name>A0A0S2DFG8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947146.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1925"/>
    <dbReference type="EnsemblBacteria" id="ALN57276">
        <property type="protein sequence ID" value="ALN57276"/>
        <property type="gene ID" value="GLE_1925"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1925"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1891"/>
    <dbReference type="OMA" id="ICEQRAR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="158" mass="17466" checksum="1B7E32B5A044662E" modified="2016-02-17" version="1">MTATDYRFAAATAADIERLIPVLREFYAVEHLPWNEPALRRALGALVADPNAGRLRLIVRDGEIAGYFVLGFCFSLEFGGRFGLLDELFVLPAHRGGGLAKRALGEVEALCRAEGLDALRLEVNDDNAHARGIYERAGYVAHPRRLMTLWLRDQGTAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFN4</accession>
    <name>A0A0S2DFN4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="12">M13 family metallopeptidase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="11">Peptidase, family M13</fullName>
            <ecNumber evidence="11">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FE772_10190</name>
        <name evidence="11" type="ORF">GLE_2006</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M13 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="11"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947206.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57356">
        <property type="protein sequence ID" value="ALN57356"/>
        <property type="gene ID" value="GLE_2006"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2006"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1973"/>
    <dbReference type="OMA" id="APRNHDA"/>
    <dbReference type="OrthoDB" id="305005at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08662">
        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
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        <property type="entry name" value="PTHR11733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00786">
        <property type="entry name" value="NEPRILYSIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242161" evidence="8">
        <location>
            <begin position="24"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M13_N" evidence="10">
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            <begin position="66"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M13" evidence="9">
        <location>
            <begin position="498"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN57356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW25983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="702" mass="77362" checksum="15B46CC5C29C2FCA" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFQ2</accession>
    <name>A0A0S2DFQ2_LYSEN</name>
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        <submittedName>
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        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">FE772_10175</name>
        <name evidence="2" type="ORF">GLE_2003</name>
    </gene>
    <organism evidence="2 4">
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    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_2003"/>
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        <property type="gene ID" value="GLE_2003"/>
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        <property type="component" value="Chromosome"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="31"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="291" mass="33000" checksum="8FEBCBBEC622E247" modified="2016-02-17" version="1">MSSSLFPVHHRYVQADGLRVFYREAGDPSAPTLLLLHGFPTSSLMFRELIQRLAGRFHLVAPDLPGFGFTEVPDARGYVYDFDHLGRTLEAFVDALDLQRYTLYVFDYGAPAGLRLALAKPERVSGLISQNGNAYLEGLGEAWDPMRRYWADPSADNREALRQFLSLEATRWQYENGEPDPTLVAPEAYHLDYLLMQRSGNADIQLDLTLDYANNLTLYPQFQQFFRERRVPTLVVWGRHDPFFIPPGAQAYRRDNPDAQVELLDAGHFALATHGAHIARRIEDVFGAARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFQ9</accession>
    <name>A0A0S2DFQ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_10695</name>
        <name evidence="3" type="ORF">FE772_10530</name>
        <name evidence="1" type="ORF">GLE_2081</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD63952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947263.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2081"/>
    <dbReference type="EnsemblBacteria" id="ALN57431">
        <property type="protein sequence ID" value="ALN57431"/>
        <property type="gene ID" value="GLE_2081"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63952">
        <property type="protein sequence ID" value="OPD63952"/>
        <property type="gene ID" value="BV903_10695"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2081"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2046"/>
    <dbReference type="OMA" id="FYIKMSE"/>
    <dbReference type="OrthoDB" id="2096782at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD63952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="97" mass="10940" checksum="CD469E86F53A7C96" modified="2016-02-17" version="1">MELLTLDHFSSHVNETYAARINDGEVPFVLVEARALSTQPQPMAGRVPFSLLFRNASAFLFPQQIYPMRHASIGEVGIFLVPVAREREGFLYQAVFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFU0</accession>
    <name>A0A0S2DFU0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polysaccharide deacetylase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Polysaccharide deacetylase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_17215</name>
        <name evidence="4" type="ORF">FE772_09615</name>
        <name evidence="2" type="ORF">GLE_1877</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000046">
        <property type="protein sequence ID" value="OPD62675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947115.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000046.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1877"/>
    <dbReference type="EnsemblBacteria" id="ALN57229">
        <property type="protein sequence ID" value="ALN57229"/>
        <property type="gene ID" value="GLE_1877"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62675">
        <property type="protein sequence ID" value="OPD62675"/>
        <property type="gene ID" value="BV903_17215"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1877"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1848"/>
    <dbReference type="OMA" id="NHAMRDE"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="23"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="229" mass="24824" checksum="0B3CDC4E79A22CE7" modified="2016-02-17" version="1">MDYHAFLAQRPRAYLGRGLPRRRAIALSFDDGPGQATPALLAALRELEVAATFFCVGRLLRAVPWLSARMLADGHELANHSMSHADASGLGADALLHEEVAPAAAELRRAGADTLSARLFRPAFGEIRADQVDLLARHGYTVAGWSIDPCDWLEPDAPGHVDCVSGAVLAQAHPGAIVLLHDGDDEHGRARPRIVEIVRELVPALRAQGYGFVRVGDLWREREAQRAQA</sequence>
</entry>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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            <begin position="1"/>
            <end position="33"/>
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        <location>
            <begin position="241"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="719" mass="77446" checksum="8E0816DBF8885218" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
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    </dbReference>
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            <begin position="28"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="330" mass="34764" checksum="576D30973A932F7A" modified="2016-02-17" version="1">MAFQRKRAPAHDPLPSPRVKAVVFDRYGAPEVLRAIELPMPQAAAGEVRVRVRAAGVRPSDIALRSGLGARAGGRSGARFPRRLGNEFAGVVDQVGAGVSGFQPGDEVMGWAAAMSYAEALTVPVDQLVHKPHTMTWAVAGALPSTGQTAHAALRQLEVGAGHTLLIHGAAGALGCVAVQLAVAWGARVIGTAAAADHDYLRTLGAQPVADDDGGIERVRALAPAGVDALFDASGDDGFARWLQRIAAARALSLSPRHGLPALRSQRSRERLAELVAMHQRHGLLVPVREMFPLTRAAEAHRAVERGPARGKVVLMVYEAMPLSLLRLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG77</accession>
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        </submittedName>
    </protein>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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        <property type="gene ID" value="GLE_2214"/>
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    </dbReference>
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            <end position="24"/>
        </location>
    </feature>
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        <location>
            <begin position="25"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57563.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW26143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="153" mass="16312" checksum="9492B2256B8E8C2D" modified="2016-02-17" version="1">MNCKSRILGSSLGLLLLIAPHADAQKRRAQQQPPKDNATYTAALARSAETCPEHSDQRTRPGVVAVPAAALKVLESRGYALCPDTRLDTTTPVVWYGKQGVFAWNPASAGAPKILAAQAAAYARSEEFPGATVVWKSNGKLAEGALVPSFRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGU6</accession>
    <name>A0A0S2DGU6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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            <end position="32"/>
        </location>
    </feature>
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        <location>
            <begin position="47"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="113" mass="11440" checksum="EE8102F96133F41A" modified="2016-02-17" version="1">MANGEVDHGRFSGEAVGRPRAPAAASRRGRAVRAAGARAQTVIGGTGIEAGDMGTACMGPDMHGREAGGATARARTGSRRRGAPAARVPVPRRAVPASPVRPGSIQCCRARSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH23</accession>
    <name>A0A0S2DH23_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">GLE_2626</name>
    </gene>
    <organism evidence="2 3">
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="GLE_2626"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2626"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="40" mass="4397" checksum="7A640D03322FE0B5" modified="2016-02-17" version="1">MLPQRQIREQARAQRRSRPLPALPAAGETMVSRTLGGAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHA1</accession>
    <name>A0A0S2DHA1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type VI secretion system Vgr family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Type VI secretion system tip protein VgrG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">tssI</name>
        <name evidence="5" type="ORF">FE772_12950</name>
        <name evidence="4" type="ORF">GLE_2581</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VgrG protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947653.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2581"/>
    <dbReference type="EnsemblBacteria" id="ALN57930">
        <property type="protein sequence ID" value="ALN57930"/>
        <property type="gene ID" value="GLE_2581"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2581"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2540"/>
    <dbReference type="OMA" id="RPFAYEL"/>
    <dbReference type="OrthoDB" id="1880900at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006531">
        <property type="entry name" value="Gp5/Vgr_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017847">
        <property type="entry name" value="T6SS_RhsGE_Vgr_subset"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006533">
        <property type="entry name" value="T6SS_Vgr_RhsGE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037026">
        <property type="entry name" value="Vgr_OB-fold_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04717">
        <property type="entry name" value="Phage_base_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01646">
        <property type="entry name" value="vgr_GE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03361">
        <property type="entry name" value="VI_Rhs_Vgr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage_base_V" evidence="3">
        <location>
            <begin position="385"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="460"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="646" mass="71947" checksum="A729086900784D32" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHD3</accession>
    <name>A0A0S2DHD3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2663</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947714.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2663"/>
    <dbReference type="EnsemblBacteria" id="ALN58011">
        <property type="protein sequence ID" value="ALN58011"/>
        <property type="gene ID" value="GLE_2663"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2663"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2622"/>
    <dbReference type="OMA" id="ALNIMWD"/>
    <dbReference type="OrthoDB" id="290349at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="463"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="724" mass="79021" checksum="59402B4E0E6F84C3" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHI0</accession>
    <name>A0A0S2DHI0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57920">
        <property type="protein sequence ID" value="ALN57920"/>
        <property type="gene ID" value="GLE_2571"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2571"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2530"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="39" mass="4222" checksum="5643A7EDB8F9B281" modified="2016-02-17" version="1">MQCNSHFYSEFFVMPGFTFVASAGISGTSLRPGIAHRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHM2</accession>
    <name>A0A0S2DHM2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2574</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2574"/>
    <dbReference type="EnsemblBacteria" id="ALN57923">
        <property type="protein sequence ID" value="ALN57923"/>
        <property type="gene ID" value="GLE_2574"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2574"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2533"/>
    <dbReference type="OMA" id="FMKIDGA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036624">
        <property type="entry name" value="Hcp1-lik_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008514">
        <property type="entry name" value="T6SS_Hcp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05638">
        <property type="entry name" value="T6SS_HCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141452">
        <property type="entry name" value="SSF141452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="163" mass="17397" checksum="2A6D4433D6AF94A3" modified="2016-02-17" version="1">MHLKFGPGDVEIKGASNHSKHKDEVPILAWSWGTSNTGNLHTGAGYAAGGKANVQDISITKYIDSCSNALLNACCTGARVENATLYVTNATGEQTDFLTIELSDGVMVTAVSTGGSGGEERLTENITLHFGKFKYAFQPQDDKGKKQGGTKDFTFSMQEVKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHP6</accession>
    <name>A0A0S2DHP6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycosyl hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Glycosyl hydrolase, family 9</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_12735</name>
        <name evidence="7" type="ORF">GLE_2536</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947617.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2536"/>
    <dbReference type="EnsemblBacteria" id="ALN57885">
        <property type="protein sequence ID" value="ALN57885"/>
        <property type="gene ID" value="GLE_2536"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2536"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2498"/>
    <dbReference type="OMA" id="VDVHGGW"/>
    <dbReference type="OrthoDB" id="1226595at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02850">
        <property type="entry name" value="E_set_Cellulase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004197">
        <property type="entry name" value="Cellulase_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001701">
        <property type="entry name" value="Glyco_hydro_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02927">
        <property type="entry name" value="CelD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00759">
        <property type="entry name" value="Glyco_hydro_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242225" evidence="5">
        <location>
            <begin position="36"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="domain" description="CelD_N" evidence="6">
        <location>
            <begin position="57"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW26402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="628" mass="67531" checksum="73E6BE80E06BE430" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHS0</accession>
    <name>A0A0S2DHS0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">30S ribosomal protein S6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">rpsF</name>
        <name evidence="9" type="ORF">BV903_18680</name>
        <name evidence="11" type="ORF">D9T17_15350</name>
        <name evidence="10" type="ORF">FE772_13285</name>
        <name evidence="8" type="ORF">GLE_2650</name>
    </gene>
    <organism evidence="8 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 12">C3</strain>
        </source>
    </reference>
    <reference evidence="9 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">OH11</strain>
        </source>
    </reference>
    <reference evidence="10 15" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Binds together with S18 to 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the bacterial ribosomal protein bS6 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000052">
        <property type="protein sequence ID" value="OPD62383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000037">
        <property type="protein sequence ID" value="ROU06067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947704.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000037.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2650"/>
    <dbReference type="EnsemblBacteria" id="ALN57998">
        <property type="protein sequence ID" value="ALN57998"/>
        <property type="gene ID" value="GLE_2650"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62383">
        <property type="protein sequence ID" value="OPD62383"/>
        <property type="gene ID" value="BV903_18680"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2650"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2609"/>
    <dbReference type="OMA" id="ITEASPM"/>
    <dbReference type="OrthoDB" id="1631889at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00473">
        <property type="entry name" value="bS6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00360">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000529">
        <property type="entry name" value="Ribosomal_S6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020814">
        <property type="entry name" value="Ribosomal_S6_plastid/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035980">
        <property type="entry name" value="Ribosomal_S6_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribosomal_S6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011">
        <property type="entry name" value="PTHR21011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01250">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54995">
        <property type="entry name" value="SSF54995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00166">
        <property type="entry name" value="S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="100"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="100"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN57998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD62383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW26492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROU06067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="142" mass="16397" checksum="D24A92237D76D1C1" modified="2016-02-17" version="1">MRHYEVVFLVHPDQSEQVPAMIERYKSLIEAGEGKIHRLEDWGRRQLAYPIENLVKAHYVLLNIEVTQTVLNELVDGFRFNDAVLRHLVMKRDEADTEQSLIMKFKDEKGDKPERGERRRRDDDSDSAVGSADSAEDTTEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHW6</accession>
    <name>A0A0S2DHW6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/beta hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Hydrolase, alpha/beta fold family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_14460</name>
        <name evidence="3" type="ORF">GLE_2898</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947891.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2898"/>
    <dbReference type="EnsemblBacteria" id="ALN58246">
        <property type="protein sequence ID" value="ALN58246"/>
        <property type="gene ID" value="GLE_2898"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2898"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2860"/>
    <dbReference type="OMA" id="QLITPYD"/>
    <dbReference type="OrthoDB" id="721431at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="Hydrolase_4" evidence="2">
        <location>
            <begin position="73"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="265" mass="29702" checksum="242704B1A355754F" modified="2016-02-17" version="1">MARNPRLFQSLAAIAGVAAAGYVSICGWMYFKQRDLMYFPQNTRLGADMTDYTVERGDAVLRGWRLNAGREKALIYFGGNAERIENMREILAQWFPDRTIYLLSYRGFGASDGAPAEPELFADALAIFDQVAREHPRQPVSVIGRSLGSGVASFVAGKRPVERLALVTPFDSLGDTAQAHYRWLPTRWLVRDRYDSIANLRGYFGPILVVRASNDDVIPPPNTTRLVHSLQTRPQGVEVVQLRGADHHNIGTYPEYGQALREFID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHW9</accession>
    <name>A0A0S2DHW9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">ABC transporter, ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_13565</name>
        <name evidence="5" type="ORF">GLE_2709</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947756.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2709"/>
    <dbReference type="EnsemblBacteria" id="ALN58057">
        <property type="protein sequence ID" value="ALN58057"/>
        <property type="gene ID" value="GLE_2709"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2709"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2668"/>
    <dbReference type="OMA" id="YAEHPRT"/>
    <dbReference type="OrthoDB" id="1179151at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="18"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="50"/>
            <end position="57"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW26537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="299" mass="33269" checksum="A1091E225E59FF66" modified="2016-02-17" version="1">MTHSLHTPPLRDAAGAVVRARGLRKTYRNKAALAGTDFDIPAGRIVGLIGPNGAGKTTALKAVLGLTSFEGELSVLGLDPRTQRDELMREVCFIADVAVLPRWLRVREAIEFVAGVHPRFDRAKCERFLHGTQLKPDLRVREMSKGMIVQLHLALVMAIDARLLVLDEPTLGLDILYRKQFYQRLLEDYFDENKTIVVTTHQVEEIEHILTDVMFIRDGKIVLDCPMENVGERFVEVLVDRDKAEHARTLGPLDERALPFGKTVMLFDGVAAAQLDGLGETRTPGLADLFVATMKGTYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI34</accession>
    <name>A0A0S2DI34_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 10">Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex</fullName>
            <ecNumber evidence="5 10">2.3.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">2-oxoglutarate dehydrogenase complex component E2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">sucB</name>
        <name evidence="15" type="ORF">FE772_13635</name>
        <name evidence="14" type="ORF">GLE_2724</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">C3</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2] + succinyl-CoA = (R)-N(6)-(S(8)-succinyldihydrolipoyl)-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2] + CoA</text>
            <dbReference type="Rhea" id="RHEA:15213"/>
            <dbReference type="Rhea" id="RHEA-COMP:10581"/>
            <dbReference type="Rhea" id="RHEA-COMP:10582"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83120"/>
            <dbReference type="EC" id="2.3.1.61"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="10">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.61" evidence="5 10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947767.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2724"/>
    <dbReference type="EnsemblBacteria" id="ALN58072">
        <property type="protein sequence ID" value="ALN58072"/>
        <property type="gene ID" value="GLE_2724"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2724"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2682"/>
    <dbReference type="OMA" id="MKVPSPG"/>
    <dbReference type="OrthoDB" id="1626282at2"/>
    <dbReference type="UniPathway" id="UPA00868">
        <property type="reaction ID" value="UER00840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045252">
        <property type="term" value="C:oxoglutarate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004149">
        <property type="term" value="F:dihydrolipoyllysine-residue succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033512">
        <property type="term" value="P:L-lysine catabolic process to acetyl-CoA via saccharopine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006255">
        <property type="entry name" value="SucB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01347">
        <property type="entry name" value="sucB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 10" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="12">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="13">
        <location>
            <begin position="124"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="99"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN58072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW26548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="404" mass="42544" checksum="146B0942CE53165F" modified="2016-02-17" version="1">MSTEIKVPVLPESVSDATIATWHKKPGDAVKRDENLVDLETDKVVLEVPSPVDGVLKEIKFEEGATVTSQQLIAIVEAGAAAAASAPAAEAAPAAAKTEAAPAAGAQPVTPKADAPKAPAANDQLPPGARFAANTQGVDASQVEGTGRKGAVTKEDIVNYAKNGGVGSAAGARPEERVPMTRMRARIAERLMQSKNSIAMLTSFNEVNLGKVMAMRKELGESFEKANGVKLGFMSFFAKAAANALQRHPIVNASVDGNDVIYHGYADISIAVSTDKGLVTPVLRNVERLGFADIEKAIGDYAKKARDGKLALEDLQGGTFTITNGGTFGSLMSTPIVNPPQSAILGMHAIKERAIVENGQVVAAPMMYIALSYDHRIIDGKDAVLFLVDIKNQLENPHRMLLGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIL1</accession>
    <name>A0A0S2DIL1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TrbI/VirB10 family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">VirB10 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">virB10</name>
        <name evidence="9" type="ORF">BV903_06250</name>
        <name evidence="10" type="ORF">FE772_14085</name>
        <name evidence="8" type="ORF">GLE_2820</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TrbI/VirB10 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000011">
        <property type="protein sequence ID" value="OPD64805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947839.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000011.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2820"/>
    <dbReference type="EnsemblBacteria" id="ALN58168">
        <property type="protein sequence ID" value="ALN58168"/>
        <property type="gene ID" value="GLE_2820"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64805">
        <property type="protein sequence ID" value="OPD64805"/>
        <property type="gene ID" value="BV903_06250"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2820"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2777"/>
    <dbReference type="OMA" id="PGKDRNT"/>
    <dbReference type="OrthoDB" id="552092at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16429">
        <property type="entry name" value="VirB10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.260">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005498">
        <property type="entry name" value="T4SS_VirB10/TraB/TrbI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042217">
        <property type="entry name" value="T4SS_VirB10/TrbI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03743">
        <property type="entry name" value="TrbI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="105"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="110"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD64805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW26621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="409" mass="43470" checksum="5B8A2DD765080505" modified="2016-02-17" version="1">MSQNMPPNQPGQPDNGNPQDGGSYGYAGANPYYGQQQGGEAAAPNLDANAPLLKSTDVQRLNRKALLFLGGIVLLLLVVAFFLLKSATGSDDKPKKVDEEVISVPDAPVTTQQPPAPLPPLPQEPVPVEPIPVAPQQPQQQQRAEGEADMRDRGPSLVERRMAGDGGSNNGNASSDGMTAADQQYLQALTQQQNGGQAPARAEREMPTSAQPLYNPDTLLLRGTYIRCVMETRIITDVPGFTSCVVTEPIYSVNGRRLLLPKGSKVSGRYQNNNGDIKRVAVVWDRITTPTGLDVNMASPGVDNLGGAGIPGQYDAHWGSRIASALLISLISDAFKYAGAKNGPESTTATPGGTVITQPYESNTAKAMERLANQALDKSVNRPATITINQGSVVNIYVAKDVDFSSVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIL8</accession>
    <name>A0A0S2DIL8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polyhydroxyalkanoic acid synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_03030</name>
        <name evidence="4" type="ORF">D9T17_16970</name>
        <name evidence="3" type="ORF">FE772_14945</name>
        <name evidence="1" type="ORF">GLE_2988</name>
    </gene>
    <organism evidence="1 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 5">C3</strain>
        </source>
    </reference>
    <reference evidence="2 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">OH11</strain>
        </source>
    </reference>
    <reference evidence="3 8" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000005">
        <property type="protein sequence ID" value="OPD65506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000041">
        <property type="protein sequence ID" value="ROU05867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947962.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2988"/>
    <dbReference type="EnsemblBacteria" id="ALN58336">
        <property type="protein sequence ID" value="ALN58336"/>
        <property type="gene ID" value="GLE_2988"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65506">
        <property type="protein sequence ID" value="OPD65506"/>
        <property type="gene ID" value="BV903_03030"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2988"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2949"/>
    <dbReference type="OMA" id="WNGDRVD"/>
    <dbReference type="OrthoDB" id="1712653at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013433">
        <property type="entry name" value="PHA_gran_rgn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09650">
        <property type="entry name" value="PHA_gran_rgn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02610">
        <property type="entry name" value="PHA_gran_rgn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD65506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROU05867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="91" mass="10180" checksum="2B92464414070430" modified="2016-02-17" version="1">MPSIDIRHPHSLAPAKARKAVEDVAKKLAERFDIQYEWDGDVLNFARSGVDGKIAVSPEHLRVTAQLGFLLGAMKGPIEAEIRRVLEEKFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIM0</accession>
    <name>A0A0S2DIM0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3008</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58356">
        <property type="protein sequence ID" value="ALN58356"/>
        <property type="gene ID" value="GLE_3008"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3008"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2969"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="42" mass="4676" checksum="3E85213B4A4592B4" modified="2016-02-17" version="1">MRSVRRRLRGAYCAAPGQGSGYAASPRAARRRTHAASARRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIW6</accession>
    <name>A0A0S2DIW6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pkn1</name>
        <name evidence="9" type="ORF">GLE_3143</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948075.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3143"/>
    <dbReference type="EnsemblBacteria" id="ALN58490">
        <property type="protein sequence ID" value="ALN58490"/>
        <property type="gene ID" value="GLE_3143"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3143"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3101"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="91"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="303"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN58490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="997" mass="108653" checksum="E167774FEBA5E930" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIY9</accession>
    <name>A0A0S2DIY9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Chorismate mutase</fullName>
            <ecNumber evidence="2">5.4.99.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_2900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate biosynthesis; prephenate biosynthesis; prephenate from chorismate: step 1/1.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.5" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2900"/>
    <dbReference type="EnsemblBacteria" id="ALN58248">
        <property type="protein sequence ID" value="ALN58248"/>
        <property type="gene ID" value="GLE_2900"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2900"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2862"/>
    <dbReference type="OMA" id="RSAPDCP"/>
    <dbReference type="UniPathway" id="UPA00120">
        <property type="reaction ID" value="UER00203"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004106">
        <property type="term" value="F:chorismate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046417">
        <property type="term" value="P:chorismate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.59.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036263">
        <property type="entry name" value="Chorismate_II_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008240">
        <property type="entry name" value="Chorismate_mutase_periplasmic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036979">
        <property type="entry name" value="CM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002701">
        <property type="entry name" value="CM_II_prokaryot"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01817">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00830">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48600">
        <property type="entry name" value="SSF48600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01806">
        <property type="entry name" value="CM_mono2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51168">
        <property type="entry name" value="CHORISMATE_MUT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595216" description="Chorismate mutase" evidence="4">
        <location>
            <begin position="31"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate mutase" evidence="5">
        <location>
            <begin position="17"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="190" mass="20526" checksum="21AA409C842F1940" modified="2016-02-17" version="1">MRTLAMRLRRRWLATAFAAAALLVALSATAQSPTPSGFERVAELSAQRLLLADAVAASKRASGKPVEDAQREGEQLARVREQATARALPAEPTAAFFRAQMEANKLVQYRLLAEPGRAGAAVDLAPVRAKLDAINAQLLDALPAALSQARGDDCARRASDARKRAARRHRLDELHRTALARAFGDLCRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIZ1</accession>
    <name>A0A0S2DIZ1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">IS30 family transposase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">ISMsm8, transposase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Integrase core domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FE772_19495</name>
        <name evidence="8" type="ORF">FE772_23780</name>
        <name evidence="5" type="ORF">GLE_3147</name>
        <name evidence="6" type="ORF">GLE_3974</name>
    </gene>
    <organism evidence="5 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 9">C3</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the transposition of the insertion element.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transposase IS30 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948078.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58494">
        <property type="protein sequence ID" value="ALN58494"/>
        <property type="gene ID" value="GLE_3147"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59316">
        <property type="protein sequence ID" value="ALN59316"/>
        <property type="gene ID" value="GLE_3974"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3147"/>
    <dbReference type="KEGG" id="lez:GLE_3974"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3104"/>
    <dbReference type="OMA" id="RKTITWD"/>
    <dbReference type="OrthoDB" id="1780129at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025246">
        <property type="entry name" value="IS30-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001598">
        <property type="entry name" value="Transposase_IS30_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13936">
        <property type="entry name" value="HTH_38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01043">
        <property type="entry name" value="TRANSPOSASE_IS30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="4">
        <location>
            <begin position="188"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="154"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW27496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW28218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="353" mass="40635" checksum="4DFFAE8E3FEC0156" modified="2016-02-17" version="1">MGQQYSHLSAEERGAIMVLIAQGASGRQIAQTLGRAQSTIARELRRNGYRSDLAAPLRGRPRLEPDYDATRAGRRAQRLRRRARVRRKLRRDTVLWRRVRYWLERCWSPQQIADKLRDLYPDRPWLRVSHETIYTAIYAMPRGELRRQVTRLLRQGRKSGRRTRQGSDARGHLPDLPNIRLRPPAAHERLMPGHWEGDLIVGAHNRSAIGVLVCRRTLYVKLVKLADATAHTVLEAFSSAFEGVPESLKKTLTYDQGKEMASHRQLSERTGLAIYFADPHSPWQRGTCENTNGLLRQYFPKGTDLSVHSAQRLKEVAWEMNNRPRRSLGRRSPVEVLYEELKNPRAQGDALGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ02</accession>
    <name>A0A0S2DJ02_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipoprotein-releasing system ATP-binding protein LolD</fullName>
            <ecNumber evidence="6">7.6.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">lolD</name>
        <name evidence="8" type="ORF">GLE_3038</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell inner membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.-" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3038"/>
    <dbReference type="EnsemblBacteria" id="ALN58385">
        <property type="protein sequence ID" value="ALN58385"/>
        <property type="gene ID" value="GLE_3038"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3038"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2998"/>
    <dbReference type="OMA" id="HDMSLAR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044873">
        <property type="term" value="P:lipoprotein localization to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042953">
        <property type="term" value="P:lipoprotein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015854">
        <property type="entry name" value="ABC_transpr_LolD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011924">
        <property type="entry name" value="LolD_lipo_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24220:SF654">
        <property type="entry name" value="PTHR24220:SF654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02211">
        <property type="entry name" value="LolD_lipo_ex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="2"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="230" mass="24720" checksum="B2890CE5B07DA08D" modified="2016-02-17" version="1">MISCQGLAMTYSEGTLRTPVFNGLDFAVNKGETVAILGASGAGKSTLLHLLGGLDTPTAGEVFVAGQRMNSLSDRARGLLRNRALGFVYQFHHLLPEFTALENVMLPVLLGGRGSPPVKEATQRATALLESVGLGHRLNHKPGELSGGERQRAAVARALVNRPACVLGDEPTGNLDEKTAATVFELMLALNRDQGTSLVMVTHDRRLARRLDRVMELHEGKLRQLPPGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ35</accession>
    <name>A0A0S2DJ35_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58466">
        <property type="protein sequence ID" value="ALN58466"/>
        <property type="gene ID" value="GLE_3119"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3119"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3076"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="196" mass="21000" checksum="1C7829046650FF07" modified="2016-02-17" version="1">MGGLQLDAFRSATTHRRTEIRPQRSRVPNRPVAGGPRLFWAGLRPFWGGATGCRGRGFSPDAFRSAATHHRTETCLHRPRVPQPTVLGRASAVVAGLPLLWEGSGCCGRGFSPDAFRSATTHRHAQRRPNAADCASQPRAPNFRPLRRSRRRPVIAASTPPTGAGAPMRAARHAHAASRPAPEARVGPSAAAPRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJE4</accession>
    <name>A0A0S2DJE4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioesterase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58644">
        <property type="protein sequence ID" value="ALN58644"/>
        <property type="gene ID" value="GLE_3298"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3298"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3248"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="251" mass="26669" checksum="C4938BE769502243" modified="2016-02-17" version="1">MSDSNNEAAPKAKTAKPPSKQALKQTSKQAATPAAGQTAKQAGKKTSPRKRAPRKRNSETAAPAAVESVAAAAPQADAGIVAAAAPAAEPRPARAQLEPAAQPQAAPPAQLVESFAVAPAALIRVPLSVRWRDLDAFNHVNNSKFLSYLEEARLRWMVTLPGHGMDEHVAPVVAAAHLNYRRPIEWPNEIDIELFVERLGNTSLSVGHRIVGANDPTALYCDGNVVLVWIHRETGQPAALPEPVRAACAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJV6</accession>
    <name>A0A0S2DJV6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948306.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3455"/>
    <dbReference type="EnsemblBacteria" id="ALN58800">
        <property type="protein sequence ID" value="ALN58800"/>
        <property type="gene ID" value="GLE_3455"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3455"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3403"/>
    <dbReference type="OMA" id="MPVDEIH"/>
    <dbReference type="OrthoDB" id="520320at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="PTHR33361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595261" evidence="1">
        <location>
            <begin position="37"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="616" mass="69038" checksum="93066BC23CA28A98" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKF3</accession>
    <name>A0A0S2DKF3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BV903_21515</name>
        <name evidence="9" type="ORF">FE772_17230</name>
        <name evidence="7" type="ORF">GLE_3500</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000071">
        <property type="protein sequence ID" value="OPD61859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948337.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000071.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3500"/>
    <dbReference type="EnsemblBacteria" id="ALN58845">
        <property type="protein sequence ID" value="ALN58845"/>
        <property type="gene ID" value="GLE_3500"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61859">
        <property type="protein sequence ID" value="OPD61859"/>
        <property type="gene ID" value="BV903_21515"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3500"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3445"/>
    <dbReference type="OMA" id="RANPHKA"/>
    <dbReference type="OrthoDB" id="1329125at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PTHR11101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="348"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD61859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW27118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="375" mass="39173" checksum="18B6CCE38A4F982C" modified="2016-02-17" version="1">MLTLVLVVILAALIFEYVNGFHDTANSIATVVATKVLSPMQAVMLAASTNLVGALWGTAVAKTIASGLIDAGVVEVGSQLLLCALLGGIIWNLITWWLGLPSSSSHALIGGLCGAAIAAASNNWHAVVWSHPAEPIWKSAGVLWKVIVPMFTSPVLGFAAGFLVMGVLFALISAMAASGGVLRRIARPRWVNGFFGKAQLLSAAGMGFAHGMNDAQKTMGIIALALISAQQAGTLDNLPAWLAFLHPSPGAIAHNDIDTWIKLTCAIVMAAGTAAGGWRIIKTLGHKLVKLHPIHGFAAETSAASVIMAASSLGIPVSTTHNISAAIMGVGTAKRFNSIKWTVVEKMIWAWILTIPAAGGIAYGLFELMRFMGWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKP5</accession>
    <name>A0A0S2DKP5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">50S ribosomal protein L30</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rpmD</name>
        <name evidence="9" type="ORF">BV903_22945</name>
        <name evidence="11" type="ORF">D9T17_09520</name>
        <name evidence="10" type="ORF">FE772_18560</name>
        <name evidence="7" type="ORF">GLE_3772</name>
        <name evidence="8" type="ORF">LEN_1371</name>
        <name evidence="12" type="ORF">SAMN05421681_11021</name>
    </gene>
    <organism evidence="7 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 13">C3</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2016" name="DNA Res." volume="0" first="0" last="0">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer, Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M497-1</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="3">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">ATCC 29487</strain>
        </source>
    </reference>
    <reference evidence="8 16" key="4">
        <citation type="journal article" date="2017" name="DNA Res." volume="24" first="169" last="177">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
            <dbReference type="PubMed" id="28065880"/>
            <dbReference type="DOI" id=".1093/dnares/dsw055"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 16">M497-1</strain>
        </source>
    </reference>
    <reference evidence="9 15" key="5">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 15">B25</strain>
        </source>
    </reference>
    <reference evidence="11 17" key="6">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 17">OH11</strain>
        </source>
    </reference>
    <reference evidence="10 18" key="7">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 18">YC36</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2 5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL30 family.</text>
    </comment>
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        <property type="protein sequence ID" value="ALN59116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="BAV96858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000077">
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        <property type="protein sequence ID" value="QCW27344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="ROU07199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="SDY03490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="NZ_RCTY01000023.1"/>
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    <dbReference type="EnsemblBacteria" id="ALN59116">
        <property type="protein sequence ID" value="ALN59116"/>
        <property type="gene ID" value="GLE_3772"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAV96858">
        <property type="protein sequence ID" value="BAV96858"/>
        <property type="gene ID" value="LEN_1371"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61599">
        <property type="protein sequence ID" value="OPD61599"/>
        <property type="gene ID" value="BV903_22945"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY03490">
        <property type="protein sequence ID" value="SDY03490"/>
        <property type="gene ID" value="SAMN05421681_11021"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Ribosomal_L30_bac-type"/>
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    </dbReference>
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        <property type="entry name" value="rpmD_bact"/>
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        <location>
            <begin position="11"/>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAV96858.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD61599.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27344.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROU07199.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY03490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000183696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000218824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="65" mass="7277" checksum="684BB0905FD44108" modified="2016-02-17" version="1">MAKNEAGTGTVKVRLVKGLRGTQSRHRLSVRALGLNKLNDVRELKDSPQVRGLINKVHYLVQVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKU4</accession>
    <name>A0A0S2DKU4_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">Nuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_17355</name>
        <name evidence="3" type="ORF">GLE_3528</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
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            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58872">
        <property type="protein sequence ID" value="ALN58872"/>
        <property type="gene ID" value="GLE_3528"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3528"/>
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    <dbReference type="OrthoDB" id="1639453at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="195" mass="20579" checksum="F8ED1108E86AC4E4" modified="2016-02-17" version="1">MSDDNDKRWYTRVPAISVALVAFLVTLTTLVNNVREIGGLKDKKPAATVAAPATPAPEVKPAEPKAPTRYSVVLTLEKIEVVNDGTSGSTSWTFDVSAGGQDLFELPARDYNDAEDSRIATPRTSDPSMGRVTLVPGQEMLVKIGGRSGGLISKLSASGTATLVAERALAPVKVVAADPRDGEFIFHFATAATPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL15</accession>
    <name>A0A0S2DL15_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">2-polyprenyl-6-methoxyphenol 4-hydroxylase</fullName>
            <ecNumber evidence="5">1.14.13.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ubiH</name>
        <name evidence="5" type="ORF">GLE_3904</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UbiH/COQ6 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.-" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3904"/>
    <dbReference type="EnsemblBacteria" id="ALN59246">
        <property type="protein sequence ID" value="ALN59246"/>
        <property type="gene ID" value="GLE_3904"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3904"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3841"/>
    <dbReference type="OMA" id="KRWFARQ"/>
    <dbReference type="UniPathway" id="UPA00232"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010971">
        <property type="entry name" value="UbiH/COQ6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01988">
        <property type="entry name" value="Ubi-OHases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="4">
        <location>
            <begin position="23"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="436" mass="46461" checksum="F6D685B07659C764" modified="2016-02-17" version="1">MTSDATPHFSAGAPDPAIHASHDVLIVGGGLVGASLAIALDRIGLDVGLVEAAPPGALPAVFDERNLSFAEATLNALDALGVLARLRAPTGPIRRIHISRRGDFGRTVLEAQRYGREEFGRVVVARDFGEALEARLAELPRLLRYRPVRFVGLADGGDGWRAVRLADGAGERTVRARLLVAADGTRSGVREALRIGTEEHDYGQTLFVARLRGERAPDGTAYERLGRDGPTALLPRGDRHYGLIHGVASVDADAVAALDEAGFLARVQDAFGWRAGRLLSCGARSLYPAIRVLAQRTVAARAVLVGNAAQTIHPIGAQGFNLGLRDAMTLAELIEDRRRAGDGDCGSDALLARYLERRREDRERTVGFSDGLARLSANDTELMRPLRSLGLFAFDRLASAQSFLVGGAMGYRGDVPALCRNDRAAAVSGGERGGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLH0</accession>
    <name>A0A0S2DLH0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4021</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59363">
        <property type="protein sequence ID" value="ALN59363"/>
        <property type="gene ID" value="GLE_4021"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4021"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3958"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="52" mass="5572" checksum="53C6E1F2A9675B81" modified="2016-02-17" version="1">MVGYAALPFQLLQMGAQPTRRTDNQRGPMTLEVEDALGVDSVPGLAELEGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLM3</accession>
    <name>A0A0S2DLM3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">6,7-dimethyl-8-ribityllumazine synthase</fullName>
            <shortName evidence="7">DMRL synthase</shortName>
            <shortName evidence="7">LS</shortName>
            <shortName evidence="7">Lumazine synthase</shortName>
            <ecNumber evidence="4 7">2.5.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 8" type="primary">ribH</name>
        <name evidence="9" type="ORF">BV903_07695</name>
        <name evidence="10" type="ORF">FE772_20355</name>
        <name evidence="8" type="ORF">GLE_4151</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>(2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) + 2 H2O + phosphate</text>
            <dbReference type="Rhea" id="RHEA:26152"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58201"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="2.5.1.78"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the DMRL synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.78" evidence="4 7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000015">
        <property type="protein sequence ID" value="OPD64535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948827.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4151"/>
    <dbReference type="EnsemblBacteria" id="ALN59493">
        <property type="protein sequence ID" value="ALN59493"/>
        <property type="gene ID" value="GLE_4151"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64535">
        <property type="protein sequence ID" value="OPD64535"/>
        <property type="gene ID" value="BV903_07695"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4151"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4093"/>
    <dbReference type="OMA" id="CQGVTQG"/>
    <dbReference type="OrthoDB" id="1680292at2"/>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00404"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009349">
        <property type="term" value="C:riboflavin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000906">
        <property type="term" value="F:6,7-dimethyl-8-ribityllumazine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09209">
        <property type="entry name" value="Lumazine_synthase-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.960">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00178">
        <property type="entry name" value="Lumazine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034964">
        <property type="entry name" value="LS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002180">
        <property type="entry name" value="LS/RS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036467">
        <property type="entry name" value="LS/RS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21058">
        <property type="entry name" value="PTHR21058"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00885">
        <property type="entry name" value="DMRL_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52121">
        <property type="entry name" value="SSF52121"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00114">
        <property type="entry name" value="lumazine-synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0436">Ligase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="6 7 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="5-amino-6-(D-ribitylamino)uracil binding" evidence="7">
        <location>
            <begin position="57"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-amino-6-(D-ribitylamino)uracil binding" evidence="7">
        <location>
            <begin position="81"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="1-deoxy-L-glycero-tetrulose 4-phosphate binding" evidence="7">
        <location>
            <begin position="86"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>5-amino-6-(D-ribitylamino)uracil</name>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>5-amino-6-(D-ribitylamino)uracil</name>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>(2S)-2-hydroxy-3-oxobutyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD64535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="155" mass="16522" checksum="A9E09BE92CBA22DE" modified="2016-02-17" version="1">MPHYEGDLRSPPGARYAIIASRWNPRITDTLVAGARKTFAEHGIAEDAIDVVRVPGAWELPVLARRLAAAGQHAAVVALGCVVRGDTRHYEQVADGCSDGLMRVSLDYGLPIANGVLAVERHEDAENRAGGSHGNKGEEAALAALEMSHLLEQLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLX8</accession>
    <name>A0A0S2DLX8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphate-selective porin O and P</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3953</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3953"/>
    <dbReference type="EnsemblBacteria" id="ALN59295">
        <property type="protein sequence ID" value="ALN59295"/>
        <property type="gene ID" value="GLE_3953"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3953"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3890"/>
    <dbReference type="OMA" id="YTGRTNT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010870">
        <property type="entry name" value="Porin_O/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07396">
        <property type="entry name" value="Porin_O_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595242" evidence="1">
        <location>
            <begin position="22"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="380" mass="42007" checksum="E7C2AC79CF9D7DED" modified="2016-02-17" version="1">MRFERVCWGALSWLALSPAWAADGGYSVLGDWPVKVVSESGIEAGLKGNFSYDVARFDGAPGFADGDAWRRQELNAYVRKPGVFELTLGYDLHNEVWLDNFVRVSGAAGDLRIGQFKTPVGYEESAVGTTATTFMERALPVTAFYAGRRLGVDWTYEKIPNWYLNAAVQAGGDLLGDNHGRTLGARAVFNPVKDDAQVLHLGLSASNEKRDDDTLRLQVRPEAFLTARRLVDTGALNRVEGISRYGLEAIWQRGPLLLQSEYLGIGVDRYGVADYSADGYYLAASWVATGEKRGYKSGAFGNVKPSRAWGAVELAARYSRIDLDDAGVALGGRQSDWTFGANWYIGQHFRLQFNYVWTDAARRGVELDPEIAQLRAQVYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM19</accession>
    <name>A0A0S2DM19_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 11">Anthranilate synthase component 1</fullName>
            <ecNumber evidence="5 11">4.1.3.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11 14" type="primary">trpE</name>
        <name evidence="15" type="ORF">FE772_20980</name>
        <name evidence="14" type="ORF">GLE_4285</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">C3</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>chorismate + L-glutamine = anthranilate + H(+) + L-glutamate + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:21732"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="4.1.3.27"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 1/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 11">Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the anthranilate synthase component I family.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.27" evidence="5 11"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948933.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4285"/>
    <dbReference type="EnsemblBacteria" id="ALN59626">
        <property type="protein sequence ID" value="ALN59626"/>
        <property type="gene ID" value="GLE_4285"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4285"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4224"/>
    <dbReference type="OMA" id="GCVGYLD"/>
    <dbReference type="OrthoDB" id="1786019at2"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004049">
        <property type="term" value="F:anthranilate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005256">
        <property type="entry name" value="Anth_synth_I_PabB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="PTHR11236"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00564">
        <property type="entry name" value="trpE_most"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="10 11 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Anth_synt_I_N" evidence="13">
        <location>
            <begin position="27"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate_bind" evidence="12">
        <location>
            <begin position="223"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN59626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW27749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="491" mass="54132" checksum="331CB1FD950FF463" modified="2016-02-17" version="1">MISHELFQQQAADGYTRIPVVREVLSDLDTPLSVYLKLADGPYTYLFESVEGGERFARYSIIGLPAQRVYAFAGHALFVTENGELVDSRTVDDPFAEVERLRAEHKVPKIDGLPGFAGGLVGWFGFECIQYIEPRLAGGDKPDELGTPDILLMQSEEVAVFDNLKGRLYLIVHADPSQPQAYARANRRLDQLVHRLRIGGPGYPETLDSVGLDEGDFVSGFTREGFIDAVERSKELIRAGDIFQVVLSQRLSVPFKARPVDVYRALRALNPSPYMYFLDVGGTQVVGSSPEILVRLQGEEVTVRPIAGTRPRGKTVDEDHALEAELLADPKERAEHLMLIDLGRNDVGRVSKAGTVEVGEQFVIERYSHVMHIVSEVTGRLKDGMSYADVLRATFPAGTVSGAPKIRALEVIREFEPVKRNVYSGAVGYIGWHGDADTAIAIRTAVIQDGRLHVQAGAGIVYDSDPQKEWEETMNKGRALFRAVAEAARGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNL5</accession>
    <name>A0A0S2DNL5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_23035</name>
        <name evidence="1" type="ORF">GLE_4739</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949276.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60080">
        <property type="protein sequence ID" value="ALN60080"/>
        <property type="gene ID" value="GLE_4739"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4739"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4673"/>
    <dbReference type="OrthoDB" id="2060175at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="83" mass="9724" checksum="CF7778130BA3E2B7" modified="2016-02-17" version="1">MAVFRLPIRLIRERFGGDNFDDAGDWADGWLRDRGERRYRIEYSFDTDHANPWFHAMVMRIEGLPDAVGEALRRRLAEEGLGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNL9</accession>
    <name>A0A0S2DNL9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4906</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60247">
        <property type="protein sequence ID" value="ALN60247"/>
        <property type="gene ID" value="GLE_4906"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4906"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="59" mass="6270" checksum="68AA15CEFDE0BFA2" modified="2016-02-17" version="1">MEQSGHGGARRLWVSPVAPLQRGAGMNAILKAASPGDKLRFLNQQMIQSQPCPAAACPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNS6</accession>
    <name>A0A0S2DNS6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4953</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60294">
        <property type="protein sequence ID" value="ALN60294"/>
        <property type="gene ID" value="GLE_4953"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4953"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="11"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="86" mass="9487" checksum="ABD842FF87106013" modified="2016-02-17" version="1">MCFAWGCVQADGNSNSNSNSNSNSNSNSNSNSNTLWVPEFVGTRCRDKRRRTARQTGKEKGRGNGRGLRSSRGRSRARHLPLRCGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNT3</accession>
    <name>A0A0S2DNT3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4897</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60238">
        <property type="protein sequence ID" value="ALN60238"/>
        <property type="gene ID" value="GLE_4897"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4897"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4828"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="87" mass="9292" checksum="4469D3B9C06647D3" modified="2016-02-17" version="1">MGRELSAGGGGRRRCVALSPLTEATNSPHRHSGESRNPFCRCRCCCSCSPPSPLQSSRSPGGRAHGCARAPWGRMPLMARPRAAFEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNX2</accession>
    <name>A0A0S2DNX2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLE_4945</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_MTAY01000044.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5093"/>
    <dbReference type="EnsemblBacteria" id="ALN60434">
        <property type="protein sequence ID" value="ALN60434"/>
        <property type="gene ID" value="GLE_5093"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62810">
        <property type="protein sequence ID" value="OPD62810"/>
        <property type="gene ID" value="BV903_16695"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5093"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5018"/>
    <dbReference type="OMA" id="WQPSYAE"/>
    <dbReference type="OrthoDB" id="948440at2"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
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        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
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        <location>
            <begin position="199"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="381" mass="41818" checksum="C9839D46E4A58983" modified="2016-02-17" version="1">MRIGLDYRAATLAPGSGPARQVLALERALRRRPDTETVLFTEAPLDHPHRAIAVAADLPAAAPTGAGASVGAAAGLRRRWRFEAGFLPAALRAEQVDVYIAAAEGGLPVWRKPASVRQVLLLHDLFKLTLRRPKSSPLRALAARMLDEAAIGHSIASADAIWTPSRYTTAECGRLYPAHAHKLYVLPDAVAPMPAPAERSRLGQPLPPRYWLLVGTREPRRNADLFLRAWLDARRQHYDTPDLVVVGSPADVPAELQRLNGVHWFEQVADDELARLYYDAERLWQPSYAEGFGLPVLEALAAGTPVAVAEGGALEEVAPVDMPRFDPHDRPQLAQLMIRLSRESVVGNAEQRRAFAQRFAPNAYAARVGALLDELLKRSDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPG5</accession>
    <name>A0A0S2DPG5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_11060</name>
        <name evidence="5" type="ORF">D9T17_04145</name>
        <name evidence="4" type="ORF">FE772_24720</name>
        <name evidence="2" type="ORF">GLE_5101</name>
    </gene>
    <organism evidence="2 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">C3</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 9" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000026">
        <property type="protein sequence ID" value="OPD63842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000012">
        <property type="protein sequence ID" value="ROU08483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949554.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000012.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60442">
        <property type="protein sequence ID" value="ALN60442"/>
        <property type="gene ID" value="GLE_5101"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63842">
        <property type="protein sequence ID" value="OPD63842"/>
        <property type="gene ID" value="BV903_11060"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5101"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5026"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU08483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="118" mass="12771" checksum="6449E5572932C53F" modified="2016-02-17" version="1">MSTSDLGISMTNERIASGEARSTSGVKAAKGGSWFEVLAAALGDILGDRVNAMMDAKNRMVENYKETLDPKSGEQQSKEYMRAMTDFQTQSQIFGIESNAIKSALDSIGNGLKEISKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ16</accession>
    <name>A0A0S2DQ16_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Outer membrane lipid asymmetry maintenance protein MlaD</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Toluene ABC transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mlaD</name>
        <name evidence="4" type="ORF">FE772_25335</name>
        <name evidence="3" type="ORF">GLE_5235</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949654.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5235"/>
    <dbReference type="EnsemblBacteria" id="ALN60576">
        <property type="protein sequence ID" value="ALN60576"/>
        <property type="gene ID" value="GLE_5235"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5235"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5153"/>
    <dbReference type="OMA" id="QYQFPKD"/>
    <dbReference type="OrthoDB" id="807474at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015914">
        <property type="term" value="P:phospholipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030970">
        <property type="entry name" value="ABC_MlaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003399">
        <property type="entry name" value="Mce/MlaD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02470">
        <property type="entry name" value="MlaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04430">
        <property type="entry name" value="OM_asym_MlaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MlaD" evidence="2">
        <location>
            <begin position="40"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="190" mass="19493" checksum="C90E11888B8D7719" modified="2016-02-17" version="1">MSVRSPRIEFAVGAFLLLALASLLVLAIASTNGKFGFGRDNYEVTAKFTSIGALRPNAPVKIGGVNVGQVADISLDPKSYASVVTLAIDKRYNKLSADTSAGIFTSGLLGESYIGLTPGGDPEDLKPGDEIYLTQPAIDLIQLVGKYMFSGGGAQGGGNGTGAEPAKPADAGTPDYLKGEQPAPSSESKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ43</accession>
    <name>A0A0S2DQ43_LYSEN</name>
    <protein>
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            <fullName evidence="3">2OG-Fe(II) oxygenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Prolyl 4-hydroxylase, alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_25595</name>
        <name evidence="2" type="ORF">GLE_5295</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949698.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5295"/>
    <dbReference type="EnsemblBacteria" id="ALN60636">
        <property type="protein sequence ID" value="ALN60636"/>
        <property type="gene ID" value="GLE_5295"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5295"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5213"/>
    <dbReference type="OMA" id="GETEFFY"/>
    <dbReference type="OrthoDB" id="1139586at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2OG-FeII_Oxy_3" evidence="1">
        <location>
            <begin position="146"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="249" mass="28119" checksum="BE21B6B5DDEAB7A7" modified="2016-02-17" version="1">MSSPADAVHEPLPAAATGGDDFIEVYPEALTREQCEQLVRRFDASRDSEPGRVGGGVMPDLKDSRDLTITGRDGWKDVEQTLNLAVFRGLLQYLRRYPHTMIAPLMLETPGADGKRHRITAERMAQMDDNALSPVAQTVFRPGAINLQRYTANRGGYPYWHCELYPRDPHADTLHRHVLWTIYLNDGFEEGETEFLYQRRKIAPRAGDLLIAPAAFTHTHRGNRPKGGDKYIATSWILFQRAERLYAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ64</accession>
    <name>A0A0S2DQ64_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2783 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_25615</name>
        <name evidence="1" type="ORF">GLE_5299</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949702.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5299"/>
    <dbReference type="EnsemblBacteria" id="ALN60640">
        <property type="protein sequence ID" value="ALN60640"/>
        <property type="gene ID" value="GLE_5299"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5299"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5217"/>
    <dbReference type="OrthoDB" id="2069137at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021233">
        <property type="entry name" value="DUF2783"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10932">
        <property type="entry name" value="DUF2783"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="72" mass="7753" checksum="811F3B7664105CB8" modified="2016-02-17" version="1">MSALNLQPNLARADEVYQRLIELHQGLDEAASRRADARLVLILINHIGDADTVLAAIAVAGRVARPAQEEPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQB5</accession>
    <name>A0A0S2DQB5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">F5/8 type C domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_5067</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ALN60408">
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        <property type="term" value="P:carbohydrate metabolic process"/>
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        <property type="project" value="InterPro"/>
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        <property type="entry name" value="FA58C"/>
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        <property type="entry name" value="Galactose-bd-like_sf"/>
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        <property type="entry name" value="Glyco_hydro_29"/>
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        <property type="entry name" value="Glycoside_hydrolase_SF"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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            <begin position="407"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN60408.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="545" mass="60809" checksum="D400E88DAA588EB4" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQC3</accession>
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            <fullName evidence="4">Transcriptional regulator, LysR family</fullName>
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        <name evidence="4" type="ORF">GLE_5375</name>
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    <organism evidence="4 5">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 5">C3</strain>
        </source>
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        <property type="component" value="Chromosome"/>
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        <property type="project" value="InterPro"/>
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        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
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        <property type="entry name" value="WH_DNA-bd_sf"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
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        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="318" mass="35578" checksum="BA14667D0E8E235C" modified="2016-02-17" version="1">MHALLGFATAARLSNLTRAAEQMHLTVSALSHQIRTLEERLGRRLFERGPRGVRLTADGERLLSVVAPHLDALDHALRPYSPRRDEVLTLSLMASMASSWLVPRLGSFVARYPQLELNLFSSSALVDFDREPGIDAAMRGGYGRWPGLVIEHLFDETLVPVASPELVARMGGLPAQEDLHRWPLLGDLSTYWQGWFDRYGGQPPARFVAHFDDSETMHRAAVEGLGVALGRLARTRLLIRNGQLVPLSQGRLKIDWGHYLVYPQRSVDHAGLESFRSWLHEQARQYVEQMDADLAAREPAAVSAAPARPPRKPRAKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQG0</accession>
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    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5264</name>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60605">
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        <property type="gene ID" value="GLE_5264"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5264"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5183"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="47" mass="4741" checksum="7F98BDBCCE362929" modified="2016-02-17" version="1">MLIAAETKASGLKSLPQERSAQARAAVVGGPSGPTLSDPSASDVDRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQK9</accession>
    <name>A0A0S2DQK9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transporter, major facilitator family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_5412</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60753">
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        <property type="gene ID" value="GLE_5412"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5412"/>
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    <dbReference type="OMA" id="EWRGLYL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="347"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="449"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="478"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="512"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="604"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="128"/>
            <end position="627"/>
        </location>
    </feature>
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        <location>
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        <source>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN60753.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="686" mass="70590" checksum="7D3EA593C08BAD5D" modified="2016-02-17" version="1"> </sequence>
</entry>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949828.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5464"/>
    <dbReference type="EnsemblBacteria" id="ALN60805">
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        <property type="gene ID" value="GLE_5464"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64945">
        <property type="protein sequence ID" value="OPD64945"/>
        <property type="gene ID" value="BV903_05485"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5464"/>
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    <dbReference type="OMA" id="QVPAHAN"/>
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    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="ALN60805.1"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="OPD64945.1"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW24376.1"/>
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    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="178" mass="18078" checksum="D01D8F85074616AA" modified="2016-02-17" version="1">MKTASIAVLALALAAPVSAYAVDGTIHIEGSVIAPTCVLTNGPSPADIRVRLPAVAVSALSAAGEVAGRTPFIIRVADCDASTTLVQTFFEPGPTINTSNNNLTLEGGTGTAANVELQVLNADFSQVLLGNPLALQNSQQVAVDTGGAALRYYAQYYATGAASAGSANSSVTFTMIYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQP0</accession>
    <name>A0A0S2DQP0_LYSEN</name>
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        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLE_5404</name>
    </gene>
    <organism evidence="10 11">
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
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        </subcellularLocation>
    </comment>
    <comment type="similarity">
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        <property type="gene ID" value="GLE_5404"/>
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    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
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    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
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        </location>
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            <end position="691"/>
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            <end position="148"/>
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            <end position="690"/>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
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    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU003357"/>
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            <dbReference type="SAM" id="SignalP"/>
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        <source>
            <dbReference type="Pfam" id="PF00593"/>
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    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="691" mass="76085" checksum="255D55D959CE52BA" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQS3</accession>
    <name>A0A0S2DQS3_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Cytosolic protein</fullName>
        </submittedName>
    </protein>
    <gene>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_5243"/>
    <dbReference type="EnsemblBacteria" id="ALN60584">
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        <property type="gene ID" value="GLE_5243"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5243"/>
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    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="551" mass="59980" checksum="EECF8BD8D50C8388" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA24</accession>
    <name>A0A0S2DA24_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Rhs family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0040"/>
    <dbReference type="EnsemblBacteria" id="ALN55399">
        <property type="protein sequence ID" value="ALN55399"/>
        <property type="gene ID" value="GLE_0040"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0040"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.47"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
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        <source>
            <dbReference type="EMBL" id="ALN55399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="916" mass="99367" checksum="363561090EDA9920" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA39</accession>
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            <fullName evidence="3">Uncharacterized protein</fullName>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55408">
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        <property type="gene ID" value="GLE_0049"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="28"/>
        </location>
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            <begin position="38"/>
            <end position="72"/>
        </location>
    </feature>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="242" mass="27180" checksum="91627692ED24DB0B" modified="2016-02-17" version="1">MSKSNRLPALPATVLVAILAGFSHPAAAIDIVFDPKNTAESMKQLQEMKRSYDKLNDQYKELQKQYNQQLVNGQSYFGRDGVKVKLDRRPLGYGLPERCTDIKNPGPKQKELCTALVQTQNRQFNAMVDLQELTEAREGELKDIYKERSEIKPDEAGRLQANNNRLLSFQARTQVDLQNAQNLLEAYGGQVRVLEQEHSKAAQAVIEGEHTGSKIDLKKLGQGGMRAAALKAAFEVAKRRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAE9</accession>
    <name>A0A0S2DAE9_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
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        <name evidence="2" type="ORF">GLE_0014</name>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="74" mass="7972" checksum="8E63EE75AD35219A" modified="2016-02-17" version="1">MSKLRGNAPAGEEVWTARGELRNPADRSDQPGQWAPERTEEAATAASVDKTDHHERGVQLAPGVLSSARADHRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAQ7</accession>
    <name>A0A0S2DAQ7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0264</name>
    </gene>
    <organism evidence="1 2">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55623">
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="50" mass="5511" checksum="4AAD8D899EE81BDA" modified="2016-02-17" version="1">MARQHLPFQCLFPQGFQAFASFGAHTGSLLGYCHGRNPRTRCEGYVAALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAY4</accession>
    <name>A0A0S2DAY4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Integral membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_0345</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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        </lineage>
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    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_0345"/>
    <dbReference type="EnsemblBacteria" id="ALN55703">
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        <property type="gene ID" value="GLE_0345"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:cellular manganese ion homeostasis"/>
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            <end position="208"/>
        </location>
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        </location>
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            <begin position="1"/>
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        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN55703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="242" mass="24661" checksum="CF62E9069DF452AF" modified="2016-02-17" version="1">MNARAAKPTPHARSRHPEAHRSERVGWLRAAVLGANDGIVSVAGLVVGVAASGADAAAILTSGIAGTVAGAMSMAAGEYVSVRSQADTERADIAVEKRELAEDPHGELEELARIYVQRGLTADLAREVARQLTAHDALASHARDELGITDTLRARPVQAALASAGAFVSGAALPIAAVVLAPHPHVQPVAIATTLVALSVSGALAAWAGGARMLRGALRVTFWGAMAMAAATAVGRLFGVQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB19</accession>
    <name>A0A0S2DB19_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transglycosylase SLT domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_0326</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_0326"/>
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        <property type="gene ID" value="GLE_0326"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0326"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1240.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037061">
        <property type="entry name" value="Lytic_TGlycoase_superhlx_L_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012289">
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    </dbReference>
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        <property type="entry name" value="Lytic_TGlycosylase_superhlx_U"/>
    </dbReference>
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        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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            <begin position="1"/>
            <end position="23"/>
        </location>
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            <begin position="24"/>
            <end position="689"/>
        </location>
    </feature>
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            <begin position="427"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="SLT" evidence="4">
        <location>
            <begin position="506"/>
            <end position="615"/>
        </location>
    </feature>
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        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN55684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="689" mass="75683" checksum="60439623469BB82C" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB24</accession>
    <name>A0A0S2DB24_LYSEN</name>
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        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">amyA</name>
        <name evidence="4" type="ORF">GLE_0342</name>
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        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.4.1.19" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0342"/>
    <dbReference type="EnsemblBacteria" id="ALN55700">
        <property type="protein sequence ID" value="ALN55700"/>
        <property type="gene ID" value="GLE_0342"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0342"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.339"/>
    <dbReference type="OMA" id="AHNWLFT"/>
    <dbReference type="OrthoDB" id="148706at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043895">
        <property type="term" value="F:cyclomaltodextrin glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
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        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
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        <location>
            <begin position="20"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="domain" description="Aamy" evidence="3">
        <location>
            <begin position="45"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN55700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="563" mass="62099" checksum="167E3811EFF1FF98" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB38</accession>
    <name>A0A0S2DB38_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase sigma factor RpoD</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Sigma-70</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 10" type="primary">rpoD</name>
        <name evidence="11" type="ORF">FE772_02635</name>
        <name evidence="10" type="ORF">GLE_0368</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts transiently with the RNA polymerase catalytic core.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the sigma-70 factor family. RpoD/SigA subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945983.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0368"/>
    <dbReference type="EnsemblBacteria" id="ALN55726">
        <property type="protein sequence ID" value="ALN55726"/>
        <property type="gene ID" value="GLE_0368"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0368"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.365"/>
    <dbReference type="OMA" id="RDAKKEM"/>
    <dbReference type="OrthoDB" id="1565734at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00963">
        <property type="entry name" value="Sigma70_RpoD_SigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007631">
        <property type="entry name" value="RNA_pol_sigma_70_non-ess"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007127">
        <property type="entry name" value="RNA_pol_sigma_70_r1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042189">
        <property type="entry name" value="RNA_pol_sigma_70_r1_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012760">
        <property type="entry name" value="RNA_pol_sigma_RpoD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028630">
        <property type="entry name" value="Sigma70_RpoD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04546">
        <property type="entry name" value="Sigma70_ner"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03979">
        <property type="entry name" value="Sigma70_r1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02393">
        <property type="entry name" value="RpoD_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="8">
        <location>
            <begin position="411"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_sigma70" evidence="9">
        <location>
            <begin position="580"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="6">
        <location>
            <begin position="581"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="177"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-2" evidence="6">
        <location>
            <begin position="387"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-3" evidence="6">
        <location>
            <begin position="466"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-4" evidence="6">
        <location>
            <begin position="555"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Interaction with polymerase core subunit RpoC" evidence="6">
        <location>
            <begin position="411"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="194"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN55726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW24730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="622" mass="69871" checksum="C58A0EC146ACCC18" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBC1</accession>
    <name>A0A0S2DBC1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0468</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55826">
        <property type="protein sequence ID" value="ALN55826"/>
        <property type="gene ID" value="GLE_0468"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0468"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.464"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594918" evidence="2">
        <location>
            <begin position="26"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="70" mass="7596" checksum="6E83308DECAC7BEF" modified="2016-02-17" version="1">MGSGVQAWAPLFVCALFARPATVIAARACASGARLRRRDPTSPTGVDDRAPMSQQRRPNFVDQTPTARIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBD2</accession>
    <name>A0A0S2DBD2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">LysR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_03220</name>
        <name evidence="3" type="ORF">GLE_0496</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946080.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55854">
        <property type="protein sequence ID" value="ALN55854"/>
        <property type="gene ID" value="GLE_0496"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0496"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.491"/>
    <dbReference type="OMA" id="GQRLYEV"/>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="11"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="319" mass="35174" checksum="C8A330195CADF729" modified="2016-02-17" version="1">MHPMHERNGSELQQIEAFAAVAEHGGFAAAARALGRDASVVSRRIDALEARLGVRLLARTTRRVALTEVGATYLQRVQAILGELSAADIEAREAAAAPQGLLRLALPAAFAQRWIAPWLPRFLAAYPKLRLELSHSDRFIDLVADGFDAAVRIGELADSRLVARRLAGFETMLCAAPSYLARAGHPQRPDELKRHACLGMPKARFWPEWKLIKGKQRSVQRIDAAIVSDDGEGLLAACIEGAGILPAPQWLVGRELAQGQLVRVLPQWRMDYDGAIHVVLSPGRLVPAKTRAFVDWLAREFEPQPPWLRAPRARGRREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBM0</accession>
    <name>A0A0S2DBM0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acriflavine resistance protein A</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Efflux RND transporter periplasmic adaptor subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_03235</name>
        <name evidence="4" type="ORF">GLE_0499</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0499"/>
    <dbReference type="EnsemblBacteria" id="ALN55857">
        <property type="protein sequence ID" value="ALN55857"/>
        <property type="gene ID" value="GLE_0499"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0499"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.494"/>
    <dbReference type="OMA" id="DNSKMWV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="80"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="386"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="396"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN55857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW24835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="410" mass="43499" checksum="DCF46B0BD2B8DC2D" modified="2016-02-17" version="1">MDTRLFDAPLAHRAANRAGSTHRLPLIAFACLALAACGGAKDKPGKGQNPTVEVGYVVMQPTTVAITSEFNGRAVAFQSSEVRPQIGGLVQRQLFQEGSQVRAGQPLYQIDPSLYRASVEQAEADLKNARAALNAADLLAQRNKSLVGAQMISRQDYDNAVAAADQARANVAQREAALSTARINLRFATVPAPIDGRIGRSLVTVGALVTPDQAAPLATIQRLDPIYVDVQQSAQQLLTLREQLSSGNVQASQADARIFLPNGKPYPQPGTLQFSEVLVDETTGTVTLRIRVPNADGTLLPGMFLRARLAQATQTSAYRLPQQALVRGPTGDAFVWVVGADNKAVQRPIGADRVDGSDWIVTTGLNPGDKVVTQGIGSLRRDAQVRAVPASTPQKLQPPGAASAQPTKQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBN0</accession>
    <name>A0A0S2DBN0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha-1,2-mannosidase, putative</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Glycoside hydrolase family 92 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_02680</name>
        <name evidence="4" type="ORF">GLE_0378</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945991.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0378"/>
    <dbReference type="EnsemblBacteria" id="ALN55736">
        <property type="protein sequence ID" value="ALN55736"/>
        <property type="gene ID" value="GLE_0378"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0378"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.375"/>
    <dbReference type="OMA" id="TSLYFMH"/>
    <dbReference type="OrthoDB" id="100818at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005887">
        <property type="entry name" value="Alpha_mannosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041371">
        <property type="entry name" value="GH92_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012939">
        <property type="entry name" value="Glyco_hydro_92"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07971">
        <property type="entry name" value="Glyco_hydro_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17678">
        <property type="entry name" value="Glyco_hydro_92N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01180">
        <property type="entry name" value="aman2_put"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242131" evidence="1">
        <location>
            <begin position="32"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_92N" evidence="3">
        <location>
            <begin position="52"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_92" evidence="2">
        <location>
            <begin position="312"/>
            <end position="775"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN55736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW24739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="797" mass="88011" checksum="F5C94A6E2537FED7" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBZ5</accession>
    <name>A0A0S2DBZ5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP synthase gamma chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP synthase F1 sector gamma subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">F-ATPase gamma subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 10" type="primary">atpG</name>
        <name evidence="11" type="ORF">BV903_08415</name>
        <name evidence="13" type="ORF">D9T17_23715</name>
        <name evidence="12" type="ORF">FE772_04125</name>
        <name evidence="10" type="ORF">GLE_0688</name>
    </gene>
    <organism evidence="10 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 14">C3</strain>
        </source>
    </reference>
    <reference evidence="11 15" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 15">B25</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">OH11</strain>
        </source>
    </reference>
    <reference evidence="12 17" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ATPase gamma chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000017">
        <property type="protein sequence ID" value="OPD64433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000061">
        <property type="protein sequence ID" value="ROU04429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946217.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000061.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0688"/>
    <dbReference type="EnsemblBacteria" id="ALN56046">
        <property type="protein sequence ID" value="ALN56046"/>
        <property type="gene ID" value="GLE_0688"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64433">
        <property type="protein sequence ID" value="OPD64433"/>
        <property type="gene ID" value="BV903_08415"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0688"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.676"/>
    <dbReference type="OMA" id="MQITSAM"/>
    <dbReference type="OrthoDB" id="1701531at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042777">
        <property type="term" value="P:proton motive force-driven plasma membrane ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12151">
        <property type="entry name" value="F1-ATPase_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00815">
        <property type="entry name" value="ATP_synth_gamma_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035968">
        <property type="entry name" value="ATP_synth_F1_ATPase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000131">
        <property type="entry name" value="ATP_synth_F1_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023632">
        <property type="entry name" value="ATP_synth_F1_gsu_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693">
        <property type="entry name" value="PTHR11693"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00231">
        <property type="entry name" value="ATP-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00126">
        <property type="entry name" value="ATPASEGAMMA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52943">
        <property type="entry name" value="SSF52943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01146">
        <property type="entry name" value="ATPsyn_F1gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00153">
        <property type="entry name" value="ATPASE_GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0139">CF(1)</keyword>
    <keyword evidence="4 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN56046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OPD64433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW24979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROU04429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="287" mass="32029" checksum="F10030AF0EBD0121" modified="2016-02-17" version="1">MAGGREIKTKIKSVQNTRKVTRALEMVSASKIRKAQDRMKTSRPYARVIKQVIGHLAQANSDYRHPYMVERKDVKRVGYVIVSSDRGLAGGLNNNLFRKLLGEFRKWQEQGVEVDVVTIGQKASVFFRRIKVNMLASVTHLGDQPHVEQLIGVIKVVLDAYSAGTVDRVFVCYNDFVNTMTQRAAFDQLLPLPAPETQVAKHDWDYIYEPDAQTVLDHVLTRYIESLVYQAVLENVASEHAARMVAMKAASDNATKLIGTLNLVYNKARQAAITQEISEIVGGAAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC89</accession>
    <name>A0A0S2DC89_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0791</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56149">
        <property type="protein sequence ID" value="ALN56149"/>
        <property type="gene ID" value="GLE_0791"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0791"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.780"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="92" mass="10262" checksum="9A730AE248C2A1B1" modified="2016-02-17" version="1">MPARAARTGAPRRGGGSVNRIACRPLRRRAPRRSRRVCSADPRARARAARCRAPRRARFAGPARIRSRCARCRGIECGPSRRGGRSRSLDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCD9</accession>
    <name>A0A0S2DCD9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycerol kinase</fullName>
            <ecNumber evidence="5">2.7.1.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP:glycerol 3-phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Glycerokinase</fullName>
            <shortName evidence="5">GK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">glpK</name>
        <name evidence="9" type="ORF">FE772_04730</name>
        <name evidence="8" type="ORF">GLE_0812</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:21644"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.30"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="5">Inhibited by fructose 1,6-bisphosphate (FBP).</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the FGGY kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.30" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946315.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0812"/>
    <dbReference type="EnsemblBacteria" id="ALN56170">
        <property type="protein sequence ID" value="ALN56170"/>
        <property type="gene ID" value="GLE_0812"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0812"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.801"/>
    <dbReference type="OMA" id="FMLMNIG"/>
    <dbReference type="OrthoDB" id="233605at2"/>
    <dbReference type="UniPathway" id="UPA00618">
        <property type="reaction ID" value="UER00672"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004370">
        <property type="term" value="F:glycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00186">
        <property type="entry name" value="Glycerol_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018483">
        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005999">
        <property type="entry name" value="Glycerol_kin"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="252"/>
        </location>
    </feature>
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        </location>
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            <position position="17"/>
        </location>
        <ligand>
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        </ligand>
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        </location>
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        </location>
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        </location>
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        <source>
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        <source>
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        </source>
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            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="501" mass="55106" checksum="42002C13F4A1058B" modified="2016-02-17" version="1">MTQRYILAIDQGTTSSRAMLFDRDGSIVGVAQREFEQIFPRPGWVEHDPSEILASVQTTAIEVMTKARVSASQIAGIGITNQRETTVVWDRHTGQAVHNAIVWQSRQTAQICEQLKADGYEAMVRERTGLLIDAYFSGTKVKWILDNVEGARAKAERGDLLFGTIDTWLIWNLSENKAHVTDYSNASRTLMYDIHKRQWCPELLEMLGVPASMLPEVRSSSEVYAHTGARHFFNNSVPICGVAGDQQAALFGQACFEAGMAKNTYGTGCFLLMNTGEKAVRSDNGLLTTIAWGIDGKVEYALEGSIFVAGSAVQWLRDGLRMLGKASDSQAYAERARSTEGVYFVPAFVGLGAPYWRSDVRGAAFGLTRGTSKEHFVRAVLESLAYQTRDVLSAMQADAGIELTSLRADGGAIANDFTAQFQADILDVALERPRINETTALGAAYLAGLAVGFWDSREQIAQQWQIERSFAPKMLEAEREKLYAGWKRAIEATLAFSVGHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCF3</accession>
    <name>A0A0S2DCF3_LYSEN</name>
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        <submittedName>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
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            <dbReference type="EMBL" id="ALN56192.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="183" mass="20485" checksum="527637B16193CB1B" modified="2016-02-17" version="1">MRPAPQAELAAERARAGELLERLRPLCGQAFAGRIVADTPRSADDPFIGKTLIMHVRGCEADAIRVPFQVGEDRSRTWVFQRLANGLSLKHDHRHRDGSEDELTMYGGELKPGGAPGRYEFPADPHSRALFRRLGREVSVPNVWAVEIDAQRFVYELARPGRLFRVEFDLTRPVPAPPPPWGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCI5</accession>
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            <authorList>
                <person name="Kobayashi D.Y."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
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        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="308" mass="33314" checksum="FF4F2B05E67F01DA" modified="2016-02-17" version="1">MRPLPLLSLLLFAALAACSRPPLADAGDDLAAARAAHPTQLRERVRDGSPALAPPPQVLQLVQYRAEGGQLSAYQTPRPDAADKRPAIVWITGGDSNTLGDVWTEQPRDNDQTAAAFRDAGLVVMYPSLRGGNDNPGVRKGFYGEVNDVLAAADYLAKLDYVDPQRIYLGGHSTGGTLALLVAQSDARFRAVFAFGPVADVSGYGERYVPVAQDDEQEIRLRSPGYWLASIRSPVFVFEGDHDANTEDLEAMRKASANPLAHWYVVPRANHFSVLAPTNELIARKIQADTGPRTTIAFDAAELQGLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCL8</accession>
    <name>A0A0S2DCL8_LYSEN</name>
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        <submittedName>
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        </lineage>
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    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TonB-dependent receptor family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW25158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946394.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0919"/>
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        <property type="protein sequence ID" value="ALN56277"/>
        <property type="gene ID" value="GLE_0919"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0919"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Plug_dom"/>
    </dbReference>
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        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242430" evidence="6">
        <location>
            <begin position="34"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="57"/>
            <end position="164"/>
        </location>
    </feature>
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        <location>
            <begin position="320"/>
            <end position="806"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW25158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="809" mass="89037" checksum="C2EFCE03362D2AAC" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCW8</accession>
    <name>A0A0S2DCW8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_03765</name>
        <name evidence="3" type="ORF">GLE_1035</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000007">
        <property type="protein sequence ID" value="OPD65222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946478.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1035"/>
    <dbReference type="EnsemblBacteria" id="ALN56393">
        <property type="protein sequence ID" value="ALN56393"/>
        <property type="gene ID" value="GLE_1035"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65222">
        <property type="protein sequence ID" value="OPD65222"/>
        <property type="gene ID" value="BV903_03765"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1035"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1023"/>
    <dbReference type="OrthoDB" id="1519144at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595330" evidence="2">
        <location>
            <begin position="33"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD65222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="238" mass="25393" checksum="B85A70EDF938005D" modified="2016-02-17" version="1">MRTAPHNPRRTGLKAASLALLIGLGLAANVQAQTIGYNIRTGDVWVDTRLGEINDYGRRYREPFIEEMTGYYGAPRSLIDELLDRRRWAPGDVYYACALARSLGVPCLNVVREYDRNPGQGWGAVAQRMGIKPGSPAFHALKRGAVQTYDHWGYPIRVDQSVRVDWAEHGPGKGRGNANGNGKSHGGPKAHGNSGHGYDDGPGKGRGKDKGHGGGNGKGHGNGGGNGKDKGHGNGKGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDB6</accession>
    <name>A0A0S2DDB6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipopolysaccharide export system protein LptC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">lptC</name>
        <name evidence="8" type="ORF">BV903_16405</name>
        <name evidence="10" type="ORF">D9T17_21150</name>
        <name evidence="9" type="ORF">FE772_06495</name>
        <name evidence="7" type="ORF">GLE_1195</name>
    </gene>
    <organism evidence="7 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 11">C3</strain>
        </source>
    </reference>
    <reference evidence="8 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">OH11</strain>
        </source>
    </reference>
    <reference evidence="9 14" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell inner membrane</location>
            <topology evidence="6">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the LptC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000043">
        <property type="protein sequence ID" value="OPD62860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000053">
        <property type="protein sequence ID" value="ROU04949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946589.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000053.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1195"/>
    <dbReference type="EnsemblBacteria" id="ALN56553">
        <property type="protein sequence ID" value="ALN56553"/>
        <property type="gene ID" value="GLE_1195"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62860">
        <property type="protein sequence ID" value="OPD62860"/>
        <property type="gene ID" value="BV903_16405"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1195"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1180"/>
    <dbReference type="OMA" id="NVRGQYE"/>
    <dbReference type="OrthoDB" id="1983716at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015221">
        <property type="term" value="F:lipopolysaccharide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01915">
        <property type="entry name" value="LPS_assembly_LptC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010664">
        <property type="entry name" value="LipoPS_assembly_LptC-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026265">
        <property type="entry name" value="LptC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06835">
        <property type="entry name" value="LptC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04409">
        <property type="entry name" value="LptC_YrbK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN56553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD62860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW25362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROU04949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="188" mass="20457" checksum="2897F9F39934FB83" modified="2016-02-17" version="1">MNWRLLSTLVLLAAAALTGWAWWSQRDKPAAAKAASRPDYVLTDFDVVVLNKEGRESFTLRAPKLTRDPSDKTMDIATPLFLIPAKPGSNGGPWEVRSQRGWVNAEGDEVRLRGQVKADSTNAAGKPINIATEELNVFPDANKATSDVAVNMTQPGTILTGLGLDADLETKNIILKSNVKARYEAKAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDC6</accession>
    <name>A0A0S2DDC6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FE772_06245</name>
        <name evidence="9" type="ORF">GLE_1143</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1143"/>
    <dbReference type="EnsemblBacteria" id="ALN56501">
        <property type="protein sequence ID" value="ALN56501"/>
        <property type="gene ID" value="GLE_1143"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1143"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1128"/>
    <dbReference type="OMA" id="GLWIHDV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011123">
        <property type="entry name" value="Y_Y_Y"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07495">
        <property type="entry name" value="Y_Y_Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242143" description="Histidine kinase" evidence="6">
        <location>
            <begin position="26"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="769"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="822"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="1068"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="1117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW25320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="1188" mass="129627" checksum="9995D2CF743FA2AC" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDF0</accession>
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            <fullName evidence="2">Histidine kinase</fullName>
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        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_1142</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
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        </lineage>
    </organism>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
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        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="KEGG" id="lez:GLE_1142"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
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        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        </location>
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            <end position="1203"/>
        </location>
    </feature>
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        <location>
            <position position="1138"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN56500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1207" mass="132121" checksum="5F2DF53752D92523" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDG1</accession>
    <name>A0A0S2DDG1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Competence protein ComEA helix-hairpin-helix repeat region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="ALN56598"/>
        <property type="gene ID" value="GLE_1241"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1241"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1225"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TIGR00426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594741" evidence="1">
        <location>
            <begin position="33"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="122" mass="12703" checksum="2D97C8F73E00C9CF" modified="2016-02-17" version="1">MESNLKELNMKSFALIAKSLVLSLVLAGSAYASEKVNINSADAATLDRVLLNIGASKAEAIVAYRKANGAFRSVEQLALVKGIGLKTVEKNRDRIVVGGAPAQGRPINTAGAIAAPRAASKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDH4</accession>
    <name>A0A0S2DDH4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Cysteine synthase</fullName>
            <ecNumber evidence="5 11">2.5.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">cysK</name>
        <name evidence="14" type="ORF">FE772_06655</name>
        <name evidence="13" type="ORF">GLE_1229</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">C3</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>hydrogen sulfide + O-acetyl-L-serine = acetate + L-cysteine</text>
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            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.5.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-serine: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.47" evidence="5 11"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946615.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1229"/>
    <dbReference type="EnsemblBacteria" id="ALN56586">
        <property type="protein sequence ID" value="ALN56586"/>
        <property type="gene ID" value="GLE_1229"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1229"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1214"/>
    <dbReference type="OMA" id="HIAKDMT"/>
    <dbReference type="OrthoDB" id="1033353at2"/>
    <dbReference type="UniPathway" id="UPA00136">
        <property type="reaction ID" value="UER00200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005856">
        <property type="entry name" value="Cys_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005859">
        <property type="entry name" value="CysK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01139">
        <property type="entry name" value="cysK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01136">
        <property type="entry name" value="cysKM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 11" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="7 9 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PALP" evidence="12">
        <location>
            <begin position="9"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="9">
        <location>
            <begin position="177"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="10">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN56586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW25389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="325" mass="34812" checksum="68FF6C58C7311109" modified="2016-02-17" version="1">MSLHESILDTIGDTPIVKLHRIAPKHVTLYAKVESFNPGGSVKDRLALAIVLDAEQRGLLKPGQTIVEATSGNTGIALAMVAAARGYPFVAVMTETFSIERRKLMRAYGAKVILTPAAERGTGMVRKAAELAEQHGWFLARQFENPANPAYHRNTTGPEILRDFAGKRLDYFVSGWGTGGTLSGAGQILKLARPDLKIVTSEPAGASLLGGKDWQPHKIQGWTPDFVPAVLDRGIADEIRPIDDVLARDTARRLAAEEGLFVGISAGATVAAALDVAQNAAEGSVLLAMLPDTGERYLSTFLFEGVNEGSDDEWLKSLQAEEIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDJ6</accession>
    <name>A0A0S2DDJ6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56667">
        <property type="protein sequence ID" value="ALN56667"/>
        <property type="gene ID" value="GLE_1310"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1310"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1294"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="46" mass="5116" checksum="A9C5B4FD8EA37907" modified="2016-02-17" version="1">MSGANQELRRSFPAMLDRSSARPLRCVRNNCGRVKSRTGSGPPELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDN6</accession>
    <name>A0A0S2DDN6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">IS30 family transposase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">ISMsm8, transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_02610</name>
        <name evidence="9" type="ORF">FE772_05730</name>
        <name evidence="10" type="ORF">FE772_06540</name>
        <name evidence="11" type="ORF">FE772_10755</name>
        <name evidence="5" type="ORF">GLE_0363</name>
        <name evidence="6" type="ORF">GLE_1206</name>
        <name evidence="7" type="ORF">GLE_2130</name>
    </gene>
    <organism evidence="6 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 12">C3</strain>
        </source>
    </reference>
    <reference evidence="8 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the transposition of the insertion element.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transposase IS30 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945980.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55721">
        <property type="protein sequence ID" value="ALN55721"/>
        <property type="gene ID" value="GLE_0363"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56563">
        <property type="protein sequence ID" value="ALN56563"/>
        <property type="gene ID" value="GLE_1206"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57480">
        <property type="protein sequence ID" value="ALN57480"/>
        <property type="gene ID" value="GLE_2130"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0363"/>
    <dbReference type="KEGG" id="lez:GLE_1206"/>
    <dbReference type="KEGG" id="lez:GLE_2130"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1191"/>
    <dbReference type="OMA" id="QERCEKS"/>
    <dbReference type="OrthoDB" id="1780129at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025246">
        <property type="entry name" value="IS30-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001598">
        <property type="entry name" value="Transposase_IS30_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13936">
        <property type="entry name" value="HTH_38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01043">
        <property type="entry name" value="TRANSPOSASE_IS30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="4">
        <location>
            <begin position="188"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="154"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN55721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN56563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW24726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW25231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW25371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW26076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="353" mass="40549" checksum="5D863EA3D8111ECA" modified="2016-02-17" version="1">MGQQYSHLSAEERGAIMVLIAQGASGRQIAQTLGRAQSTIARELRRNGFRSHSGPPLRGRPRFDPGYDATRAGRRAQRLRRRARVRRKLRRDTVLWRRVRYWLERCWSPQQIADKLRDLYPDRPWLRVSHETIYTAIYAMPRGELRRQVTRLLRQGRKSGRRTRQGSDARGHLPDLPNIRLRPPAAHERLMPGHWEGDLIVGAHNRSAIGVLVCRRTLYVKLVKLADATAHTVLEAFSSAFEGVPESLKKTLTYDQGKEMASHRQLSERTGLAIYFADPHSPWQRGTCENTNGLLRQYFPKGTDLSVHSAQRLKEVAWEMNNRPRRSLGRRSPVEVLYEELKNPRAQGDALGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDQ5</accession>
    <name>A0A0S2DDQ5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">2-methylcitrate dehydratase</fullName>
            <ecNumber evidence="4">4.2.1.79</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">prpD</name>
        <name evidence="10" type="ORF">FE772_07020</name>
        <name evidence="9" type="ORF">GLE_1308</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S,3S)-2-methylcitrate = 2-methyl-cis-aconitate + H2O</text>
            <dbReference type="Rhea" id="RHEA:17725"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57872"/>
            <dbReference type="ChEBI" id="CHEBI:58853"/>
            <dbReference type="EC" id="4.2.1.79"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Organic acid metabolism; propanoate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PrpD family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.79" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946676.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1308"/>
    <dbReference type="EnsemblBacteria" id="ALN56665">
        <property type="protein sequence ID" value="ALN56665"/>
        <property type="gene ID" value="GLE_1308"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1308"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1292"/>
    <dbReference type="OMA" id="ECTKHLG"/>
    <dbReference type="OrthoDB" id="688128at2"/>
    <dbReference type="UniPathway" id="UPA00946"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047547">
        <property type="term" value="F:2-methylcitrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019679">
        <property type="term" value="P:propionate metabolic process, methylcitrate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012705">
        <property type="entry name" value="2Me_IsoCit_deHydtase_PrpD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036148">
        <property type="entry name" value="MmgE/PrpD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042183">
        <property type="entry name" value="MmgE/PrpD_sf_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042188">
        <property type="entry name" value="MmgE/PrpD_sf_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005656">
        <property type="entry name" value="MmgE_PrpD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045337">
        <property type="entry name" value="MmgE_PrpD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045336">
        <property type="entry name" value="MmgE_PrpD_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16943">
        <property type="entry name" value="PTHR16943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03972">
        <property type="entry name" value="MmgE_PrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19305">
        <property type="entry name" value="MmgE_PrpD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103378">
        <property type="entry name" value="SSF103378"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02330">
        <property type="entry name" value="prpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MmgE_PrpD" evidence="7">
        <location>
            <begin position="20"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="MmgE_PrpD_C" evidence="8">
        <location>
            <begin position="289"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF19305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW25452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="485" mass="53722" checksum="0347C580A3824CE5" modified="2016-02-17" version="1">MSHFDIRSTVRPDPDKPMVDIADYVADYQIDSKEAYDTARYMLLDSLACAALAMDHKECLKHLGPLVPGGEMQGGARVPFTAYQLDPVQAAYNIGVQIRWLDFNDTWLAAEWGHPSDNLGAILGVADYLGRKAEAEGGKAMTVRDVLGHAIKAHEIQGGYALKNSFNRVGLDHVILVRLASTAVTTQMLGGGKDEIVTAVSHSWIDNGVLRTYRHAPNTGPRKSWAAGDACRRAVTHALNANKGVVGYPSALSVKTWGFYDIAFKGKQFEFERPFGSYVMENVLFKISFPAEFHAQTAVECAMKLHEQVKDKLDQIERVELETQEAGVRIIDKTGPLANYADRDHCLQYMVAVPLIFGRLTADDYVDAVAADPRIDALRDKMVVKENEQFTKDYFDPDKRYIGNSVQVFFKDGTSTDKVSIDFPIGHRKRRAEGIPVLMAKFEAAIRAKLPAAQAERLLALANNPAELEALPVTEFMGLFVRQGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE47</accession>
    <name>A0A0S2DE47_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Glutathione reductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="13">Glutathione-disulfide reductase</fullName>
            <ecNumber evidence="12 13">1.8.1.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">gor</name>
        <name evidence="13" type="synonym">gorA</name>
        <name evidence="13" type="ORF">FE772_07715</name>
        <name evidence="12" type="ORF">GLE_1468</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">C3</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="7">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.7" evidence="12 13"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946799.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1468"/>
    <dbReference type="EnsemblBacteria" id="ALN56825">
        <property type="protein sequence ID" value="ALN56825"/>
        <property type="gene ID" value="GLE_1468"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1468"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1449"/>
    <dbReference type="OMA" id="MSKHYDY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006322">
        <property type="entry name" value="Glutathione_Rdtase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737">
        <property type="entry name" value="PTHR42737"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 9" id="KW-0274">FAD</keyword>
    <keyword evidence="2 9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 9 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="11">
        <location>
            <begin position="9"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="10">
        <location>
            <begin position="347"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="446"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="183"/>
            <end position="190"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="8">
        <location>
            <begin position="46"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN56825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW25568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="457" mass="48495" checksum="CA6BB60710C8DDEA" modified="2016-02-17" version="1">MSESEQAQFDLIVVGGGSGGLAGAFRAAEHGARVALLEPSLLGGTCVNVGCVPKKAMWLAADIGAKLRMAQSLGFAVDAPPQQPCELDWPTFIVHRQRYIAGIHDSYRKRLDKAGIVVAPMRARLLDARTVECENGARMGAARILIATGGHAVKPAIPGAELGGTSDDFFQWTAAPKRVAIVGAGYIAVELAGVLQALGSQVELFARGQRLLEGFDHELTAQLADDYCQSGVRLHFGHAVAALEADGARVRVRGADGALGEAFDKVLFATGRKPNSAGLGLENAGVELDANGFVRIDELNATRVAGIDAVGDVTPDPPLTPVAIAAARRLMDRLYGGGSAKLDRNDIPTVVFAHPPIGKVGLTEDEARARWGDNLHIYRAGFRPMLYALAESPQRSLFKLVCVGQERRVVGIHLLGEAADEMLQGFAVALKRGITLDDLRDTVALHPTSAEEVVLMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-06-17" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEB2</accession>
    <name>A0A0S2DEB2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1544</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56901">
        <property type="protein sequence ID" value="ALN56901"/>
        <property type="gene ID" value="GLE_1544"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1544"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1526"/>
    <dbReference type="OrthoDB" id="2011968at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="224" mass="24163" checksum="BC575F930FF36C21" modified="2016-02-17" version="1">MHDKHANDHLAEIEKRIGDDGTVNGNLKKLAKIGGAGKSGDDAKEPEEKLNPAQPSDQVAKTVNDRCPSPGAAAGAAQQQWQLCQEIVKTELAQYKYSMTMYALARTRQQRLQEIERERSDLGADEQGKLQDNTNKLLALLSRMEVDRQQSRAYMDAYAARLAYLRAVRDMLSNEVLRGKDGGGSGGGSGGGGVNGRVAAGVVGLATMKAALDAVKTERKGWPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEH2</accession>
    <name>A0A0S2DEH2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Aminotransferase, class IV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1695"/>
    <dbReference type="EnsemblBacteria" id="ALN57051">
        <property type="protein sequence ID" value="ALN57051"/>
        <property type="gene ID" value="GLE_1695"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1695"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1673"/>
    <dbReference type="OMA" id="VPWTRNE"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008696">
        <property type="term" value="F:4-amino-4-deoxychorismate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01559">
        <property type="entry name" value="ADCL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017824">
        <property type="entry name" value="Aminodeoxychorismate_lyase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="SSF56752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03461">
        <property type="entry name" value="pabC_Proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="278" mass="30264" checksum="D7E7A7770049EAC5" modified="2016-02-17" version="1">MSAADDLPEARFFRGGVRLPALPPFDRGQAYGDALFETLRAHRGELPWWDAHWARLTLGAQRLGLALPDPERVRAEALELLAGADAVLKLILSRGAGGRGYAPPARAEPVWTLSRHPLPPPPRAGGLRLRWCELRLAEQPALAGLKHCNRLEQVLARAEWDDPDIDEGLLRNVAGEAVCATAANVFVLHGRQWTTPPVDRCGVAGVCRQRLIELSAARVAAVAADELQRADAIFLCNAVRGILPVARLGERQWAPHPAVAELRRRLGDAHPAFVPGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEI4</accession>
    <name>A0A0S2DEI4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GNAT family N-acetyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">N-acetyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">N-acetyltransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_06940</name>
        <name evidence="4" type="ORF">FE772_08430</name>
        <name evidence="2" type="ORF">GLE_1623</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000013">
        <property type="protein sequence ID" value="OPD64688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057950029.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1623"/>
    <dbReference type="EnsemblBacteria" id="ALN56980">
        <property type="protein sequence ID" value="ALN56980"/>
        <property type="gene ID" value="GLE_1623"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64688">
        <property type="protein sequence ID" value="OPD64688"/>
        <property type="gene ID" value="BV903_06940"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1623"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1604"/>
    <dbReference type="OMA" id="HQRMAYV"/>
    <dbReference type="OrthoDB" id="1809950at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="22"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="190" mass="21494" checksum="5B95132B6CDA681E" modified="2016-02-17" version="1">MATRERLPPWHERQRLPNGREVLIRPVRPEDAEPLRAGFALLQPDEVRQRFLYALKELTPEMAERFTRVDPRTEFALVAAEPLPPGEALVGAVARVAIDERTQDAEFAILVSRYIANMGLGRYLMTRLVKWARGKKVHRLYGDVFEHNTPMLSLAQSLGFEREFHQDSPGLIRVSLDLRSKPAAEGTAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DES7</accession>
    <name>A0A0S2DES7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">IS1595 family transposase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_07670</name>
        <name evidence="2" type="ORF">GLE_1458</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1458"/>
    <dbReference type="EnsemblBacteria" id="ALN56815">
        <property type="protein sequence ID" value="ALN56815"/>
        <property type="gene ID" value="GLE_1458"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1458"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1438"/>
    <dbReference type="OMA" id="LTKRINH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024445">
        <property type="entry name" value="Tnp_ISXO2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024442">
        <property type="entry name" value="Transposase_Zn_ribbon"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12762">
        <property type="entry name" value="DDE_Tnp_IS1595"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12760">
        <property type="entry name" value="Zn_Tnp_IS1595"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01126">
        <property type="entry name" value="DDE_Tnp_IS1595"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS1595" evidence="1">
        <location>
            <begin position="138"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="371" mass="42443" checksum="B3ED9759B52543A4" modified="2016-02-17" version="1">MAQHFLRSSAYRDFNVSGIYAMTDEQVHDLFVQLRWNSTTHQACPWCGVWDQHYPRPIRRQWRCKSCGRDFSVTTCTVFANHKKPLRTLLLAAFYFVTSAKGIAGLGLSRTVNYSSKGAHALLGKFREALIRTQDQTPLTGIVEIDGGYFGGKPRRPNRRGRRNHQAIADRIAGRPTKHRSYAIGMTKINQEKRKNKRVVMVLRQRGEKGQGAVRTITVVARSENEADVRKLVDRYVAPDAVIMSDENPAYSLLSATHEHHAVAHSKEYVRVDGVHENQAESFYTRLRRWEYGVGHGVHRIYLADYAAEMAWREDFRRQSIRQQLEALLLRALGLGVSRWWCGYYQGKRRGSEILMNQGIPPSSVSRDSAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEZ9</accession>
    <name>A0A0S2DEZ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase, M48 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLE_1804</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1804"/>
    <dbReference type="EnsemblBacteria" id="ALN57156">
        <property type="protein sequence ID" value="ALN57156"/>
        <property type="gene ID" value="GLE_1804"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1804"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1775"/>
    <dbReference type="OMA" id="YQANCAN"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="8">
        <location>
            <begin position="102"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN57156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="306" mass="33070" checksum="6DE8D83946A40226" modified="2016-02-17" version="1">MDPYGNQARGGRRGFGGFRWWILLLFGLYAAWSWFGSAKTDPYTGETAHYGTSADEEVQLGEQAFVQVLNDANSQRALLPSSAPQSQAVSQIAQRLIDKVPQVTQALAKQNNQEAPTDYRSFKWSVAVINSQEANAFCLPGGKMAVYTGLFPVTQNDDALAVVMGHEIAHALLRHGSQRMAQQKLVQLGQVAAGAAVGGMDPQQQQMIMGALGAGAQYGLVLPYGRNHETQADKVGLMLAAAACYDPRQAVPLWQRMSQLGGGQRPAEFASTHPDPANRIQALQQLMPAALEFYQANCANKPLAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFE5</accession>
    <name>A0A0S2DFE5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphotransferase enzyme family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1867</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947107.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1867"/>
    <dbReference type="EnsemblBacteria" id="ALN57219">
        <property type="protein sequence ID" value="ALN57219"/>
        <property type="gene ID" value="GLE_1867"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1867"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1838"/>
    <dbReference type="OMA" id="HCNTFSR"/>
    <dbReference type="OrthoDB" id="1457558at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05154">
        <property type="entry name" value="ACAD10_11_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041726">
        <property type="entry name" value="ACAD10_11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="54"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="369" mass="42091" checksum="1BC88963360740BC" modified="2016-02-17" version="1">MAVVPYPNPLASAQPVEPAPRIAAASPPQDTALAATVTRWLREQGVDVGGWPQLQRLAGGMSHLTYRLRYDTHDLVLRRPLQAHGGLQRMRREFLLQTALAAHYPVPAMLRLCADPAVAGAPFYLMAHVPGLVPRRRSFADAALSADQARQACENFLDALIQLHRIDPCALGLGDAVLAPPSAHHLRKLLTHWLGRHVRLKTWHTPDLRAMGQWLIDRVPARQPACLLHNDWRLDNLVFDRDRPSRIRAVLDWEFAGLGDPLMDLGIVLSYWIEPGDHPLMRRYQWQPSHLPGMPSRDELVERYFAVTGCSDRDWTYYQVFGWFRYLLALQELHLRHALQGGEEKAFFTGVWALIHYLHWKCRALMRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFK7</accession>
    <name>A0A0S2DFK7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2014</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947212.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57364">
        <property type="protein sequence ID" value="ALN57364"/>
        <property type="gene ID" value="GLE_2014"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2014"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1979"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01839">
        <property type="entry name" value="FG-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="519"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="544" mass="56258" checksum="510C3A1CF4DB2393" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFR3</accession>
    <name>A0A0S2DFR3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">LysR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_10590</name>
        <name evidence="3" type="ORF">GLE_2094</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947273.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57444">
        <property type="protein sequence ID" value="ALN57444"/>
        <property type="gene ID" value="GLE_2094"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2094"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2058"/>
    <dbReference type="OMA" id="EPCRIEP"/>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="303" mass="33295" checksum="58CDB039D2B651ED" modified="2016-02-17" version="1">MKLTLDELLAFVSVVDTGSITAAAQTLDQTVSGVSRALARLEDKLGTTLLRRTTRRLELTEEGEAMLTRARAILASVEDAEESLALRRQQPAGRLRVNAASPFMLHAIVPLVGDFRRAFPQIELELNSNDQIIDLLEQRTDVAIRIGQLTDSTLHARPLPGSRLRVLASPAYLAARGTPREVSDLAGHTLLGFAPTQVLNRWPLRDAHGNELDIAADLHASSGETLRQLALAGEGIVCLSDFMTRQDRRSGALAQLFADRTLDVRQPINAVYYRNTQLASRIACFLDFLVRRLAPDGEATAWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFU9</accession>
    <name>A0A0S2DFU9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_09620</name>
        <name evidence="2" type="ORF">GLE_1878</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57230">
        <property type="protein sequence ID" value="ALN57230"/>
        <property type="gene ID" value="GLE_1878"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1878"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1849"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="69" mass="7300" checksum="D476F288989CDFF4" modified="2016-02-17" version="1">MRQRGDLPESAPGPAGAGEDAGAMAPAWPREPISAQRLRDAEVAQAQATLKRELVRVYAQACGACKPKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG74</accession>
    <name>A0A0S2DG74_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alpha/beta hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Hydrolase, alpha/beta fold family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_10265</name>
        <name evidence="4" type="ORF">GLE_2023</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947220.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2023"/>
    <dbReference type="EnsemblBacteria" id="ALN57373">
        <property type="protein sequence ID" value="ALN57373"/>
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    <sequence length="380" mass="42340" checksum="3C261B046C351840" modified="2016-02-17" version="1">MSRIPALLALLLAAGAAPAGAAECQDTAKYADARAVIEDLDRINSPGGIQEAYAAPIGGIRQWINVRGQDRDNPILLFVHGGPASPLIPTLWQFQRPLEEYFTVVNYDQRGAGKTYTLQDPQGYADTIHIATYVDDAIEVAQYVRQRYGKRKIVLAGHSWGTIVGMQAALKRPDLFYAYVGIGQAIKVMENEKLSFDYGMQQALARGNTAAVEEMKTIAPYPGDQPVTRERIIAARKWSQHYGGLTAYRDESPYFYRAARLSPDYVDDCERAAVDAGNVFTLGRILPEFLAVDMSGVREFPIPVVMFMGRHDYTTPSQPTAAWLARVRAPYKRGVWFERSSHMMQWEEPGKLLTSLLTYVRPLAADAQPRTAARPAPRQR</sequence>
</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 6">B25</strain>
        </source>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
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        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="324" mass="33337" checksum="EF2D05A57C82ED98" modified="2016-02-17" version="1">MTRRSLSLLIAAALASAALAACSRPPVDTAPAAAPAEAAKPAEPMPAAPAPSATAEDVHAFKIGQLSAFALKDGDIDVANDGKTFAVGRPPADVATLLSANGQPTDAVHLSIQPLLVRSGERVLLFDTGAGNASFARAGRLQASLRSAGVEPDQVTDIFISHAHPDHIGGLLSADGGLAFANAAVHLSAPEWASLQANKDNAKLAAALAPKVRAFAPNAELVPGTVKAVAVDGHTPGHSAYEIASGEERLLYIGDSAHSSIVSVQRPQWTIQFDGDAPKAEASRVALLKRIADGNLHVYAVHFPFPGLGRIKPQGEGFVWVPDA</sequence>
</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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        </source>
    </evidence>
    <sequence length="49" mass="5256" checksum="747AC81639FF094C" modified="2016-02-17" version="1">MVIDDNDVHSTVPVVRPPPAAAGLRAYSAAPCRGSRRKSRHTLRGPAFT</sequence>
</entry>
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    <accession>A0A0S2DGV9</accession>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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    </dbReference>
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        <property type="gene ID" value="GLE_2480"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2480"/>
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    <dbReference type="OMA" id="FQVRQEP"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="121" mass="12200" checksum="9A41D6FC18BBDC78" modified="2016-02-17" version="1">MLASAILLFTIAALGGVVMAAIRFAGKRNPPAWLAMLHGLLAASGLTLLAYAVCTVPVPASATLALCLFLLAAGGGAVLSLAYKWRQRLLPAWLVAGHAVAAVAGYLMLAASVLPGYAGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH01</accession>
    <name>A0A0S2DH01_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">TonB family C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLE_2540</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TonB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947620.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2540"/>
    <dbReference type="EnsemblBacteria" id="ALN57889">
        <property type="protein sequence ID" value="ALN57889"/>
        <property type="gene ID" value="GLE_2540"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2540"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2501"/>
    <dbReference type="OMA" id="SEAQAYN"/>
    <dbReference type="OrthoDB" id="1600828at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="TonB_C" evidence="10">
        <location>
            <begin position="165"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="54"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="55"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN57889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="244" mass="25880" checksum="5E3A47678FA16F72" modified="2016-02-17" version="1">MSPRARERWRWLCSLGAVLAVHGAAAAAALWWPAREPLQPQTLPAAAVMVELAPTPQAPPAPPKQLPPGPQQREQHRAATPPRPQPRLQAPPAADADVELPPPAPTPAPPAPADPADVAATLAPPDLSAPAATTYAAPQSVSGRRDDAVAQWQNLLLGHLEKFRRYPRQAQRLNQQGVAYVRFAVDRGGAVSQIRIGRSSGYPALDAGTLETVRLAAPVPAPPAQIQGDPVEVMVPVAFFIRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHC6</accession>
    <name>A0A0S2DHC6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable malate:quinone oxidoreductase</fullName>
            <ecNumber evidence="5">1.1.5.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">MQO</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Malate dehydrogenase [quinone]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">mqo</name>
        <name evidence="9" type="ORF">FE772_12025</name>
        <name evidence="8" type="ORF">GLE_2403</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>(S)-malate + a quinone = a quinol + oxaloacetate</text>
            <dbReference type="Rhea" id="RHEA:46012"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.1.5.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 5">Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the MQO family.</text>
    </comment>
    <dbReference type="EC" id="1.1.5.4" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947514.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2403"/>
    <dbReference type="EnsemblBacteria" id="ALN57752">
        <property type="protein sequence ID" value="ALN57752"/>
        <property type="gene ID" value="GLE_2403"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2403"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2365"/>
    <dbReference type="OMA" id="PHLDTRW"/>
    <dbReference type="OrthoDB" id="1371190at2"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER01008"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052589">
        <property type="term" value="F:malate dehydrogenase (menaquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008924">
        <property type="term" value="F:malate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00212">
        <property type="entry name" value="MQO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006231">
        <property type="entry name" value="MQO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06039">
        <property type="entry name" value="Mqo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01320">
        <property type="entry name" value="mal_quin_oxido"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="537"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN57752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW26291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="564" mass="62109" checksum="27DDCDAB8028DA01" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHK4</accession>
    <name>A0A0S2DHK4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide repeat</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2834</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2834"/>
    <dbReference type="EnsemblBacteria" id="ALN58182">
        <property type="protein sequence ID" value="ALN58182"/>
        <property type="gene ID" value="GLE_2834"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2834"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2792"/>
    <dbReference type="OMA" id="TEWPAST"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="93"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="347" mass="36354" checksum="1739C4F7329F5646" modified="2016-02-17" version="1">MAVTMGSGSTLAFAVAGAALVLIVLGYALHPLWRARPRLGIGLAASLALATAALYLGLGTPRALKPEQRRAPQTLAEAVTQLESELQRDPNQIEGWRLLASAYTAQGLAVKARDAYARALKLAPDNPDLLAEAAEARALATRERRFDEEAMRMLEHALQQQPMHQRARWFLGIAQRQGERPADAAKTWEPLLAVVQPGTAAGLLEQINGARKDAGLEPLSPPAPASADAAAAGPGLKVRVELAPALKARLPAGASVFVLARQDGGPPMPVAVEKHPAGSFPLEVTLDDGDSPMPTMKLSQLPKVQVLARVSASGNAIPQQGDLASAPQTVATGGADTVVVTIDRVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHL6</accession>
    <name>A0A0S2DHL6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Excinuclease ABC, C subunit</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">GIY-YIG nuclease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">uvrC</name>
        <name evidence="3" type="ORF">FE772_13650</name>
        <name evidence="2" type="ORF">GLE_2728</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58076">
        <property type="protein sequence ID" value="ALN58076"/>
        <property type="gene ID" value="GLE_2728"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2728"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2686"/>
    <dbReference type="OMA" id="WPREWKI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="100" mass="11460" checksum="FCB0CEA8F4DA84CF" modified="2016-02-17" version="1">MDANPNPLRLSARQRGTLYAGVTSDPIQRIWQHRNDLTEGFTRRHGVHVLVWYELHPDMLSAIIREKRIKSWKLELIESANPQWRDLYSAIIGASAAPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHT9</accession>
    <name>A0A0S2DHT9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromosome partition protein Smc</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">smc</name>
        <name evidence="7" type="ORF">FE772_13780</name>
        <name evidence="6" type="ORF">GLE_2758</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for chromosome condensation and partitioning.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="3">Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SMC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947791.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2758"/>
    <dbReference type="EnsemblBacteria" id="ALN58106">
        <property type="protein sequence ID" value="ALN58106"/>
        <property type="gene ID" value="GLE_2758"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2758"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2715"/>
    <dbReference type="OMA" id="HNKIAME"/>
    <dbReference type="OrthoDB" id="1149850at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030261">
        <property type="term" value="P:chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007062">
        <property type="term" value="P:sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01894">
        <property type="entry name" value="Smc_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011890">
        <property type="entry name" value="SMC_prok"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="SSF75553"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02168">
        <property type="entry name" value="SMC_prok_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="5">
        <location>
            <begin position="521"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="170"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="438"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="653"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="32"/>
            <end position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW26574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="1167" mass="129949" checksum="F42B7F903EDB9041" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHV6</accession>
    <name>A0A0S2DHV6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2687</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58035">
        <property type="protein sequence ID" value="ALN58035"/>
        <property type="gene ID" value="GLE_2687"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2687"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2646"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595204" evidence="2">
        <location>
            <begin position="28"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="86" mass="8822" checksum="237449D3BB7C059F" modified="2016-02-17" version="1">MPACPDRRRRRCIAVAACAAPTGASDAAPRLVGAAQAATAPMQTTAHLDPDRIRPPTRTPNPAAESQLPIPASGTIAPCPTAMPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHW8</accession>
    <name>A0A0S2DHW8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TldD/PmbA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_2668</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase U62 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947719.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2668"/>
    <dbReference type="EnsemblBacteria" id="ALN58016">
        <property type="protein sequence ID" value="ALN58016"/>
        <property type="gene ID" value="GLE_2668"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2668"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2627"/>
    <dbReference type="OMA" id="NVQFQRM"/>
    <dbReference type="OrthoDB" id="806701at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045569">
        <property type="entry name" value="Metalloprtase-TldD/E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045570">
        <property type="entry name" value="Metalloprtase-TldD/E_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002510">
        <property type="entry name" value="Metalloprtase-TldD/E_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035068">
        <property type="entry name" value="TldD/PmbA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036059">
        <property type="entry name" value="TldD/PmbA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01523">
        <property type="entry name" value="PmbA_TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19289">
        <property type="entry name" value="PmbA_TldD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19290">
        <property type="entry name" value="PmbA_TldD_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111283">
        <property type="entry name" value="SSF111283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PmbA_TldD" evidence="2">
        <location>
            <begin position="58"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_M" evidence="4">
        <location>
            <begin position="155"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_C" evidence="3">
        <location>
            <begin position="287"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="541" mass="58306" checksum="9F5530DD4A864F72" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHX6</accession>
    <name>A0A0S2DHX6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Oxidoreductase, short chain dehydrogenase/reductase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947712.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2660"/>
    <dbReference type="EnsemblBacteria" id="ALN58008">
        <property type="protein sequence ID" value="ALN58008"/>
        <property type="gene ID" value="GLE_2660"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2660"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2619"/>
    <dbReference type="OMA" id="ANCKAIN"/>
    <dbReference type="OrthoDB" id="1209997at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="261" mass="26793" checksum="4502A76C72020B3E" modified="2016-02-17" version="1">MDLDLTGKHALVCGASEGIGRAAARELALLGCDVTVLARRAEALAAVAAELPRRGAQAHGWIAADVSEHAALSARVQALAAGKPVQILVNNTGGPPGGPAHAAEDAAYLDAFNRHLLANHALLRAALPGMRAAQWGRVVNVISTSVKEPIVGLGVSNTIRGAVASWAKTLSRELGADGITVNNVLPGYTRTARIDQIVADRARTSGQAPEAVLEAMRKTVPANRFAEPAEIGAAIAFLCSPAAGYINGVSLAVDGGRMQSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI27</accession>
    <name>A0A0S2DI27_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF2214 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_14170</name>
        <name evidence="2" type="ORF">GLE_2838</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947849.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2838"/>
    <dbReference type="EnsemblBacteria" id="ALN58186">
        <property type="protein sequence ID" value="ALN58186"/>
        <property type="gene ID" value="GLE_2838"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2838"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2796"/>
    <dbReference type="OMA" id="WAIPLRK"/>
    <dbReference type="OrthoDB" id="1993992at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018706">
        <property type="entry name" value="DUF2214_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09980">
        <property type="entry name" value="DUF2214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="150" mass="16162" checksum="6FC4B78E4AC62FB9" modified="2016-02-17" version="1">MLTDLLLAAAHHLLLFALIAMLAAEAVLLRGPIDAAALRRLAGLDAGYGMSAVLLLVVGALRVVYGVKGQAFYLHNPWFHAKLGLFVLVALLSILPTVRFLRWRRALKADPGFLPDPRQVGALRLLIRLELLAVAAILVCAAAMARYGGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI48</accession>
    <name>A0A0S2DI48_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2783</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58131">
        <property type="protein sequence ID" value="ALN58131"/>
        <property type="gene ID" value="GLE_2783"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2783"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="72" mass="8114" checksum="64701A89BC5545D5" modified="2016-02-17" version="1">MRLGFLASGQCEQQRAQEREGNRARCRFRQLHETEDPCVLVDTSSRTSPRPARPRSARPAARTRAAGARFTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI96</accession>
    <name>A0A0S2DI96_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NTP_transf_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2904</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947896.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2904"/>
    <dbReference type="EnsemblBacteria" id="ALN58252">
        <property type="protein sequence ID" value="ALN58252"/>
        <property type="gene ID" value="GLE_2904"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2904"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2866"/>
    <dbReference type="OMA" id="CAGQTLV"/>
    <dbReference type="OrthoDB" id="2019898at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTP_transf_3" evidence="1">
        <location>
            <begin position="12"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="198" mass="20314" checksum="BB6A7ADEAE9FD6A0" modified="2016-02-17" version="1">MPIAPADLTLGLLAGGRATRLGGRDKAWLRRDGEFQVLRLAQAFAPCAGQTLVSANRDVQRYAEYGLRAVVDRSPDLGPLGGLDALAAAAATPWLLTLPVDALAAGPWLLDALAAAQAEAGQGAYAVDDDGVQPLFALWPVAPLRAALAPALAQRQLAVRGLQAALGMAMARLPGLRLGNLNTPADLAAAGIDADPMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIE1</accession>
    <name>A0A0S2DIE1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2952</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58300">
        <property type="protein sequence ID" value="ALN58300"/>
        <property type="gene ID" value="GLE_2952"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2952"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2914"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="59" mass="6874" checksum="77C12A8933F25745" modified="2016-02-17" version="1">MACAARADRPFSDTVGGRPQWWRERFFSPFAPLVRSASRRWDTIAARSHWQLSLGIRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIL2</accession>
    <name>A0A0S2DIL2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">HIT domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">HIT family hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">D9T17_17640</name>
        <name evidence="4" type="ORF">FE772_15615</name>
        <name evidence="3" type="ORF">GLE_3139</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 8">YC36</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000044">
        <property type="protein sequence ID" value="ROU05526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948072.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000044.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3139"/>
    <dbReference type="EnsemblBacteria" id="ALN58486">
        <property type="protein sequence ID" value="ALN58486"/>
        <property type="gene ID" value="GLE_3139"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3139"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3097"/>
    <dbReference type="OMA" id="NYPWFIL"/>
    <dbReference type="OrthoDB" id="1598286at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026026">
        <property type="entry name" value="HIT_Hint"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000714">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="2">
        <location>
            <begin position="36"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU05526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="136" mass="15406" checksum="5144D859E085FB86" modified="2016-02-17" version="1">MNPWHLHPQLADDTHPVAQFELCELRLMDDANHPWLILVPRVDGATELVDLDEAQQQTLTREIARVSRALQAGFAPHKLNVAALGNLVPQLHVHVIARYREDIAWPRPVWGMASAQPYSPEALVQRLHLLQRALAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIR1</accession>
    <name>A0A0S2DIR1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Surface antigen family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3056</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948010.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3056"/>
    <dbReference type="EnsemblBacteria" id="ALN58403">
        <property type="protein sequence ID" value="ALN58403"/>
        <property type="gene ID" value="GLE_3056"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3056"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3016"/>
    <dbReference type="OMA" id="TGTMRMD"/>
    <dbReference type="OrthoDB" id="1861716at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008816">
        <property type="entry name" value="Gly_zipper_2TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05433">
        <property type="entry name" value="Rick_17kDa_Anti"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595084" evidence="1">
        <location>
            <begin position="22"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Rick_17kDa_Anti" evidence="2">
        <location>
            <begin position="128"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="278" mass="28806" checksum="749178EE4C3164C0" modified="2016-02-17" version="1">MNKNMIAVAIASLLVGGVAVAAFQSFRGPAAPVAALTPAPAPGQEMPNAVNGATPAGDLAASGAINTQPQVDYADVVNVKPINQKEKLYATVIGTDPVRETSTVSTPREVCEDVVVQERLPERDGNVGGTVVGAVVGGLLGNQVGKGNGRKAATAAGAVAGGFIGNRVDRNHVGGRVVNRTERQCHTVSDSSQSSKVVAYNVTYRNPDGTTGTMRTESKPGSRISLGSENKVVGYNVTYRYQGQEQTVRMDERPTQRLPVVDGQVVTQTASLAAPGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIY2</accession>
    <name>A0A0S2DIY2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3117</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948056.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58464">
        <property type="protein sequence ID" value="ALN58464"/>
        <property type="gene ID" value="GLE_3117"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3117"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3074"/>
    <dbReference type="OMA" id="HAWANRR"/>
    <dbReference type="OrthoDB" id="1370270at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595269" evidence="2">
        <location>
            <begin position="29"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="403" mass="43465" checksum="6A137613072DF493" modified="2016-02-17" version="1">MRHRSPLLFLLPAAALPLLIGWAIGATAAPPAAAPASGPLATSAVSQALGAALRADAPAALAVLKAAPAEQFQGKDADFRQCMLERHERKAPPPVVAASATAPRDAFATQVLGIYQRYWWHAVREPQRRGELERTLKAELAAAIGEPAPGDGEEAFEALYAKLDARLRESGLHPLQGRTPPLYDLFLWGGQEQRDYTVALPGGVAQPVEVFVMDGWISRGWSHYTACGKTGAAGWVKPEGLYAVRESYGDLQGEDFKVSFLGHEAQHFADLARWPKLPPWRLEYRAKLVELAQADSSREKLLDRFYRAQDDDLDHPHPYANKRVLTDAAKALGLAADADADLRKADPAALRRVAAEALLADTRKLESEPAGTYAEPAKGEAKPAAQPQAKPADKPASKPAGKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJA5</accession>
    <name>A0A0S2DJA5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_16105</name>
        <name evidence="1" type="ORF">GLE_3249</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948152.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58595">
        <property type="protein sequence ID" value="ALN58595"/>
        <property type="gene ID" value="GLE_3249"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3249"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3203"/>
    <dbReference type="OrthoDB" id="1688127at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="121" mass="13848" checksum="C61245D241DAE1C7" modified="2016-02-17" version="1">MNPGLSEGDICTYPRSDGTWGFFWVQRVDALPDGREALSLRKFDTHTVDEVRREDEADVAELKTIRLLGHFPIVGTRVAEARPQVIGRMPVREEDLEGYRIWREAFDQGEAGVFTLELEQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJB8</accession>
    <name>A0A0S2DJB8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3288</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58634">
        <property type="protein sequence ID" value="ALN58634"/>
        <property type="gene ID" value="GLE_3288"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3288"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="49" mass="5466" checksum="79D343B49949625A" modified="2016-02-17" version="1">MAAGHPAAGSARALRLRPMAFGLWWEGLQARRCCVRSPRFQREAADRAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJR9</accession>
    <name>A0A0S2DJR9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA polymerase III subunit delta</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">DNA polymerase III, delta subunit</fullName>
            <ecNumber evidence="3">2.7.7.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">holA</name>
        <name evidence="4" type="ORF">D9T17_11070</name>
        <name evidence="3" type="ORF">GLE_3435</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">OH11</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.7.7" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000024">
        <property type="protein sequence ID" value="ROU07111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948292.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3435"/>
    <dbReference type="EnsemblBacteria" id="ALN58780">
        <property type="protein sequence ID" value="ALN58780"/>
        <property type="gene ID" value="GLE_3435"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3435"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3385"/>
    <dbReference type="OMA" id="RIPTGKP"/>
    <dbReference type="OrthoDB" id="1199768at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010372">
        <property type="entry name" value="DNA_pol3_delta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005790">
        <property type="entry name" value="DNA_polIII_delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06144">
        <property type="entry name" value="DNA_pol3_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01128">
        <property type="entry name" value="holA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_pol3_delta" evidence="2">
        <location>
            <begin position="21"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROU07111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <sequence length="348" mass="38171" checksum="F3E4FDDEF933D9E4" modified="2016-02-17" version="1">MELTPERLVAQLDQEPLRPAYLIAGPEPLRVLEAADAVRAAARAQGIGEREVFEAEGNQREPDWNALSASFRAPSLFASRRLLELRLPSGKPGKEGAEVIADFCADPPHDASLLITAGEWSKQHGGKWSEAVGRIGHLSVAWAIKPHELPEWIERRLRQRGLRADRDAVQSLADRVEGNLLAAAQEVDKLALLSDGETLTVERMQALVADAARFDVFRVLDAAMNGQGAQVSRMLAGLRAEGEAVPALLGMVVMELQRTAALARVSARGGNLSSEFKAQRIWDSKQPMYRRALQRHDARRWEALLVQAGRVDRMAKGREAGDAWVALERLLLAVAEPRALRLLAVAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJT1</accession>
    <name>A0A0S2DJT1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_08885</name>
        <name evidence="4" type="ORF">FE772_17425</name>
        <name evidence="2" type="ORF">GLE_3541</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000019">
        <property type="protein sequence ID" value="OPD64288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948367.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58885">
        <property type="protein sequence ID" value="ALN58885"/>
        <property type="gene ID" value="GLE_3541"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64288">
        <property type="protein sequence ID" value="OPD64288"/>
        <property type="gene ID" value="BV903_08885"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3541"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3485"/>
    <dbReference type="OrthoDB" id="2198664at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595125" evidence="1">
        <location>
            <begin position="27"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="74" mass="8166" checksum="A6496C232833409A" modified="2016-02-17" version="1">MKGLSARSTLLFVAVAAFGFSASVYAACQDRWCTKNYNQCRLEARADGVMTDAEFQKCFQEWSDCLLANGCQAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJW8</accession>
    <name>A0A0S2DJW8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3229</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948137.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58575">
        <property type="protein sequence ID" value="ALN58575"/>
        <property type="gene ID" value="GLE_3229"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3229"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3182"/>
    <dbReference type="OrthoDB" id="1693943at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="221" mass="23085" checksum="FB73FBC60A7A310E" modified="2016-02-17" version="1">MTERNRAQASPSRADGAGLRVIAKPPARDGRRWGAACVAVAVVGALVGWWLWPVRGATAGGMPPARIQHDAAAASVGGSPAADAAARAASRQEPPTMPSDDPDDLAAYFRPGDPEPSGAQVIEALHQAGVRTGIGAFNPPGTSPPLAGLAVPADYELPTGYVRHHQVTDEGVPIEPVLMFAPGFVLRDARGRPIAMPENRIVPPELAPPGMPQRQIEIPRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK21</accession>
    <name>A0A0S2DK21_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pilus assembly protein PilC</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Type IV pilus assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pilY1</name>
        <name evidence="8" type="ORF">FE772_17825</name>
        <name evidence="7" type="ORF">GLE_3622</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Fimbrium</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PilY1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948423.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3622"/>
    <dbReference type="EnsemblBacteria" id="ALN58966">
        <property type="protein sequence ID" value="ALN58966"/>
        <property type="gene ID" value="GLE_3622"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3622"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3566"/>
    <dbReference type="OMA" id="DPLWYAA"/>
    <dbReference type="OrthoDB" id="165468at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009289">
        <property type="term" value="C:pilus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008707">
        <property type="entry name" value="PilC_beta_prop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05567">
        <property type="entry name" value="Neisseria_PilC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0281">Fimbrium</keyword>
    <keyword evidence="3" id="KW-1029">Fimbrium biogenesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Neisseria_PilC" evidence="6">
        <location>
            <begin position="1074"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="879"/>
            <end position="898"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW27211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="1615" mass="169553" checksum="AF3748314EC3C8A1" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK23</accession>
    <name>A0A0S2DK23_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">1-deoxy-D-xylulose-5-phosphate synthase</fullName>
            <ecNumber evidence="10">2.2.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">1-deoxyxylulose-5-phosphate synthase</fullName>
            <shortName evidence="10">DXP synthase</shortName>
            <shortName evidence="10">DXPS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 12" type="primary">dxs</name>
        <name evidence="13" type="ORF">FE772_17510</name>
        <name evidence="12" type="ORF">GLE_3556</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">C3</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-glyceraldehyde 3-phosphate + H(+) + pyruvate = 1-deoxy-D-xylulose 5-phosphate + CO2</text>
            <dbReference type="Rhea" id="RHEA:12605"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="10">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Metabolic intermediate biosynthesis; 1-deoxy-D-xylulose 5-phosphate biosynthesis; 1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the transketolase family. DXPS subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.7" evidence="10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948379.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3556"/>
    <dbReference type="EnsemblBacteria" id="ALN58900">
        <property type="protein sequence ID" value="ALN58900"/>
        <property type="gene ID" value="GLE_3556"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3556"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3500"/>
    <dbReference type="OMA" id="QVGYHAQ"/>
    <dbReference type="OrthoDB" id="566385at2"/>
    <dbReference type="UniPathway" id="UPA00064">
        <property type="reaction ID" value="UER00091"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008661">
        <property type="term" value="F:1-deoxy-D-xylulose-5-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052865">
        <property type="term" value="P:1-deoxy-D-xylulose 5-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02007">
        <property type="entry name" value="TPP_DXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00315">
        <property type="entry name" value="DXP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005477">
        <property type="entry name" value="Dxylulose-5-P_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43322">
        <property type="entry name" value="PTHR43322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13292">
        <property type="entry name" value="DXP_synthase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00204">
        <property type="entry name" value="dxs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="4 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRANSKETOLASE_1" evidence="11">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="10">
        <location>
            <begin position="120"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="10">
        <location>
            <begin position="152"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="374"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN58900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW28796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="637" mass="68639" checksum="BA38EE34521BE5DB" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKF5</accession>
    <name>A0A0S2DKF5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent siderophore receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FE772_18120</name>
        <name evidence="9" type="ORF">GLE_3678</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948464.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3678"/>
    <dbReference type="EnsemblBacteria" id="ALN59022">
        <property type="protein sequence ID" value="ALN59022"/>
        <property type="gene ID" value="GLE_3678"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3678"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3620"/>
    <dbReference type="OrthoDB" id="169533at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015344">
        <property type="term" value="F:siderophore uptake transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010105">
        <property type="entry name" value="TonB_sidphr_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01783">
        <property type="entry name" value="TonB-siderophor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 9" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="94"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="7">
        <location>
            <begin position="264"/>
            <end position="736"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN59022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="737" mass="81472" checksum="8A87F85ADB4DD109" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKJ6</accession>
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            <fullName evidence="16">Excinuclease ABC, A subunit</fullName>
        </submittedName>
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        <name evidence="16" type="ORF">GLE_3682</name>
    </gene>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="UvrA_DNA-bd"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17755">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0228">DNA excision</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ABC transporter" evidence="15">
        <location>
            <begin position="528"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
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            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
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            <end position="610"/>
        </location>
    </feature>
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        <location>
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            <end position="570"/>
        </location>
        <ligand>
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        </source>
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        </source>
    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ALN59026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="877" mass="95094" checksum="59785F41B66B224A" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKL7</accession>
    <name>A0A0S2DKL7_LYSEN</name>
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        </recommendedName>
    </protein>
    <gene>
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        <name evidence="8" type="ORF">FE772_18790</name>
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    </gene>
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        <lineage>
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        </lineage>
    </organism>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="5">Methylated by PrmC. Methylation increases the termination efficiency of RF1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW27382.1"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_3815"/>
    <dbReference type="EnsemblBacteria" id="ALN59158">
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    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
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    </dbReference>
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    </dbReference>
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        <location>
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            <end position="244"/>
        </location>
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        <location>
            <position position="235"/>
        </location>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        </source>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="ALN59158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW27382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="361" mass="39743" checksum="C124A04E8F5814CC" modified="2016-02-17" version="1">MTPSLRRKLEALAERREELERLLADPGVIGDNERFRKCSREFAQLEPVALALAAETQAKADLAAAEAMRADPELRELAEEEIASAQERLQRLDVELMAHLIPKDPRDDGDLYLEVRAGTGGDEAAIFAGDLFRMYSRYAERQGWKVEVESANPGEHGGYKEVIARVEGRGAYSRLKFESGTHRVQRVPETESQGRIHTSAATVAIIAVEPEGEPIEINPADLKIDTFRSSGAGGQHVNKTESAIRITHVPSGVVVENQTERSQHANRDKALKRLQAMLADAAAAKAAAAQAQDRRLQVGSGDRSQRIRTYNFPQGRITDHRVEGLTLYDLPNVIAGDLDGLIGRLLHEHQADELARLSANT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKR2</accession>
    <name>A0A0S2DKR2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SapC</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">SapC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_18020</name>
        <name evidence="2" type="ORF">GLE_3665</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948454.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3665"/>
    <dbReference type="EnsemblBacteria" id="ALN59009">
        <property type="protein sequence ID" value="ALN59009"/>
        <property type="gene ID" value="GLE_3665"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3665"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3609"/>
    <dbReference type="OMA" id="QAHYPIV"/>
    <dbReference type="OrthoDB" id="1512520at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010836">
        <property type="entry name" value="SapC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07277">
        <property type="entry name" value="SapC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="255" mass="28106" checksum="0A099E9FC5EB0060" modified="2016-02-17" version="1">MSRTVLLNNLEHHDLRVIVARGARYGDGEMLAPTFFSEFRELQAHYPIVFQKTADGGFRSVALLGLRPGENLFLEPKSEPEPEPEPAPGAAADGERWDAHYLPMAIARLPFLIGIADEEPMVHIDLDHPRVVRGGDAGEALFLEHGGTSAFLQGVASLLRALHDGLRDDAGFIAALRRHELLEPFALDIRLDERSQHRLSGFHTIDERRLGALDGAALQALSQAGHLQAAYMAVASLSRLRDLIERLSRRHAAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKU8</accession>
    <name>A0A0S2DKU8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 6">50S ribosomal protein L20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rplT</name>
        <name evidence="9" type="ORF">BV903_16745</name>
        <name evidence="11" type="ORF">D9T17_10300</name>
        <name evidence="10" type="ORF">FE772_17570</name>
        <name evidence="7" type="ORF">GLE_3567</name>
        <name evidence="8" type="ORF">LEN_1565</name>
        <name evidence="12" type="ORF">SAMN05421681_110177</name>
    </gene>
    <organism evidence="7 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 13">C3</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="journal article" date="2016" name="DNA Res." volume="0" first="0" last="0">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer, Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">M497-1</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="3">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">ATCC 29487</strain>
        </source>
    </reference>
    <reference evidence="8 16" key="4">
        <citation type="journal article" date="2017" name="DNA Res." volume="24" first="169" last="177">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
            <dbReference type="PubMed" id="28065880"/>
            <dbReference type="DOI" id=".1093/dnares/dsw055"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 16">M497-1</strain>
        </source>
    </reference>
    <reference evidence="9 15" key="5">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 15">B25</strain>
        </source>
    </reference>
    <reference evidence="11 17" key="6">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 17">OH11</strain>
        </source>
    </reference>
    <reference evidence="10 18" key="7">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 18">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the bacterial ribosomal protein bL20 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP014940">
        <property type="protein sequence ID" value="BAV97052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000045">
        <property type="protein sequence ID" value="OPD62749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000023">
        <property type="protein sequence ID" value="ROU07335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNOG01000010">
        <property type="protein sequence ID" value="SDY07996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948387.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3567"/>
    <dbReference type="EnsemblBacteria" id="ALN58911">
        <property type="protein sequence ID" value="ALN58911"/>
        <property type="gene ID" value="GLE_3567"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAV97052">
        <property type="protein sequence ID" value="BAV97052"/>
        <property type="gene ID" value="LEN_1565"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62749">
        <property type="protein sequence ID" value="OPD62749"/>
        <property type="gene ID" value="BV903_16745"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY07996">
        <property type="protein sequence ID" value="SDY07996"/>
        <property type="gene ID" value="SAMN05421681_110177"/>
    </dbReference>
    <dbReference type="KEGG" id="lem:LEN_1565"/>
    <dbReference type="KEGG" id="lez:GLE_3567"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3511"/>
    <dbReference type="OMA" id="GRRKNVW"/>
    <dbReference type="OrthoDB" id="1932144at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000183696">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000218824">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07026">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00382">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005813">
        <property type="entry name" value="Ribosomal_L20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035566">
        <property type="entry name" value="Ribosomal_protein_L20_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10986">
        <property type="entry name" value="PTHR10986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00453">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00062">
        <property type="entry name" value="RIBOSOMALL20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74731">
        <property type="entry name" value="SSF74731"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01032">
        <property type="entry name" value="rplT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00937">
        <property type="entry name" value="RIBOSOMAL_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAV97052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD62749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROU07335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="SDY07996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000183696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000218824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="119" mass="13430" checksum="565E75AE53B58107" modified="2016-02-17" version="1">MARVKRGVTARRRHKKILKQAKGYYNARRKVFRVAKQAVTKALQYAYIGRKQKKRNFRSLWITRINAAARINGMSYSRFINGLLKAGITLDRKVLADIAVHDAKGFAALAEKAKSALAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKW1</accession>
    <name>A0A0S2DKW1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">4-hydroxythreonine-4-phosphate dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.262</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">4-(phosphohydroxy)-L-threonine dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 5" type="primary">pdxA</name>
        <name evidence="6" type="ORF">FE772_19210</name>
        <name evidence="5" type="ORF">GLE_3912</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>4-(phosphooxy)-L-threonine + NAD(+) = 3-amino-2-oxopropyl phosphate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:32275"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58452"/>
            <dbReference type="EC" id="1.1.1.262"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="4">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <text evidence="4">Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 4/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="4">The active site is located at the dimer interface.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PdxA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.262" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948641.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3912"/>
    <dbReference type="EnsemblBacteria" id="ALN59254">
        <property type="protein sequence ID" value="ALN59254"/>
        <property type="gene ID" value="GLE_3912"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3912"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3849"/>
    <dbReference type="OMA" id="TAQVVMM"/>
    <dbReference type="OrthoDB" id="1414545at2"/>
    <dbReference type="UniPathway" id="UPA00244">
        <property type="reaction ID" value="UER00312"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050570">
        <property type="term" value="F:4-hydroxythreonine-4-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042823">
        <property type="term" value="P:pyridoxal phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00536">
        <property type="entry name" value="PdxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037510">
        <property type="entry name" value="PdxA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005255">
        <property type="entry name" value="PdxA_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30004">
        <property type="entry name" value="PTHR30004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04166">
        <property type="entry name" value="PdxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00557">
        <property type="entry name" value="pdxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0170">Cobalt</keyword>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="3 4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW27449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="335" mass="34841" checksum="373CE92917C594E4" modified="2016-02-17" version="1">MTPPRLALVPGEPAGVGPELCVRLLQRPRDYDLICYADPRSLRAAADALALPLTLLPPDRPSRAPGEVAVVEIPNPVPPAFGAPEPGNAAAVIQALRDAAQACLDGRLDGVITGPVHKAVINQGGIAYTGTTELLAQQAGCEVVMMLANDIVRVGLATTHLPLRDVADAIAPEPLARTLRIVDAALRGDFGLARPRIAVLGLNPHAGEAGHLGREEIEVIEPVLAALRGEGLDLIGPLPADTAFLPAKLQGFDAVVAMYHDQGLPVLKYSGFERAVNLTLGLPYPRVAVDHGTALDLAGRGLADPSSLIAAADACARIAHIRSTRSDRNPPGGSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL21</accession>
    <name>A0A0S2DL21_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Polysaccharide pyruvyl transferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_16115</name>
        <name evidence="4" type="ORF">FE772_19045</name>
        <name evidence="2" type="ORF">GLE_3875</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000042">
        <property type="protein sequence ID" value="OPD62916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948614.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000042.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3875"/>
    <dbReference type="EnsemblBacteria" id="ALN59218">
        <property type="protein sequence ID" value="ALN59218"/>
        <property type="gene ID" value="GLE_3875"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62916">
        <property type="protein sequence ID" value="OPD62916"/>
        <property type="gene ID" value="BV903_16115"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3875"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3814"/>
    <dbReference type="OMA" id="CPSMYAF"/>
    <dbReference type="OrthoDB" id="540816at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007345">
        <property type="entry name" value="Polysacch_pyruvyl_Trfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04230">
        <property type="entry name" value="PS_pyruv_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PS_pyruv_trans" evidence="1">
        <location>
            <begin position="74"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="425" mass="47289" checksum="488B7B1CBE1E6C10" modified="2016-02-17" version="1">MSTYFLRTVHAAPATGASGRERLEASVRNTGNFFFEQAVARQLDDHRECHALEALPPDAETLVLSMSNFISPSTDLGWLADLLERLAVPRVVMIGAGAQAESYAHPVELSEGTRRFVSLLSHRSDSIGVRGHFTAEVLARVGVRNVEVIGCPSLFYACERGFRIDKPDLGGRRPRTVAHCTPYGNYRDAVGHLLSFAVRECEAYIAQSETQLLFDEESAAARAYFFHYYNNGDRSDAELEGWMRGHARWFFDMDSWLDYMAGMEFSVGARFHGSMAALQAGVPALNLACDSRTRELCEYLNLPYALLQDFDGRASAAELYESTDFSVFNAGFARKYDRYRGFLERNGLRHRLGDGAVADTDVVGRVRAASAAELLRSAAPEAVDRRVWQRELALRLADDRSERVMKLAESGRFDLRDGADAEPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL78</accession>
    <name>A0A0S2DL78_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TPM_phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_3925</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948651.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3925"/>
    <dbReference type="EnsemblBacteria" id="ALN59267">
        <property type="protein sequence ID" value="ALN59267"/>
        <property type="gene ID" value="GLE_3925"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3925"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3862"/>
    <dbReference type="OMA" id="ALTQKNY"/>
    <dbReference type="OrthoDB" id="1720318at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007621">
        <property type="entry name" value="TPM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04536">
        <property type="entry name" value="TPM_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="1 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594922" description="TPM_phosphatase domain-containing protein" evidence="6">
        <location>
            <begin position="29"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="TPM_phosphatase" evidence="7">
        <location>
            <begin position="68"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="294"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="317"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="344" mass="36776" checksum="A59BE7C5ED7EDB7D" modified="2016-02-17" version="1">MSMAPRRPSRPWAALLAALWLCAAPLAAREPAPTTAARPAEGVETVATDAAEAAEARGAQVPKLTGPVVDLTGTLDAAASSRLSERSLELQRRKGAQLMLLILDSTGGEDIAAYAGRVFAQWRPGRAGVDDGVLIVVAKRDRQMRIHLGRGLEATIPDATAQRVIDEILTPAFRDEDYPGGLERAYDALIGLIDGTPLPEPEPDHLPWPLLIFAGLMVSPFVLIPLFGMRAAWRTGPAAFFGRWALIAVVAVAAYFITVPKLAPDLPEWQRWMPMALLTYIASAFAWVSAFAGSDGGRGRPWDDRDEDERRRRRSSSSSSSSSNSSSYSGGGGSSDGGGASGRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL92</accession>
    <name>A0A0S2DL92_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_19680</name>
        <name evidence="5" type="ORF">GLE_4012</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:10137"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:82620"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948714.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4012"/>
    <dbReference type="EnsemblBacteria" id="ALN59354">
        <property type="protein sequence ID" value="ALN59354"/>
        <property type="gene ID" value="GLE_4012"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4012"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3949"/>
    <dbReference type="OMA" id="KPITAHW"/>
    <dbReference type="OrthoDB" id="1800563at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LMWPc" evidence="4">
        <location>
            <begin position="6"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW27529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="164" mass="17775" checksum="045B70C38DF23AA3" modified="2016-02-17" version="1">MSPRPYNLLFLCTGNSARSILAEGLVTHLSNGRIQGYSAGSQPTGRVNPLALETLRNFGCATEGFSSKTWDAFAGADAPAMDFIITVCDNAAGEACPLWPGKPVSAHWGVPDPAGVEGSEEKRRKAFMDAALTLKRRIELFLSLPLHRLDAMSLQHELRDIGHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLA1</accession>
    <name>A0A0S2DLA1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">UDP-3-O-acyl-N-acetylglucosamine deacetylase</fullName>
            <shortName evidence="12">UDP-3-O-acyl-GlcNAc deacetylase</shortName>
            <ecNumber evidence="4 12">3.5.1.108</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12 13" type="primary">lpxC</name>
        <name evidence="14" type="ORF">BV903_07560</name>
        <name evidence="15" type="ORF">FE772_20220</name>
        <name evidence="13" type="ORF">GLE_4125</name>
    </gene>
    <organism evidence="13 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">C3</strain>
        </source>
    </reference>
    <reference evidence="14 17" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">B25</strain>
        </source>
    </reference>
    <reference evidence="15 18" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 18">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 12">Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + H2O = a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + acetate</text>
            <dbReference type="Rhea" id="RHEA:67816"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:137740"/>
            <dbReference type="ChEBI" id="CHEBI:173225"/>
            <dbReference type="EC" id="3.5.1.108"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the LpxC family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.108" evidence="4 12"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000015">
        <property type="protein sequence ID" value="OPD64513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948805.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4125"/>
    <dbReference type="EnsemblBacteria" id="ALN59467">
        <property type="protein sequence ID" value="ALN59467"/>
        <property type="gene ID" value="GLE_4125"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64513">
        <property type="protein sequence ID" value="OPD64513"/>
        <property type="gene ID" value="BV903_07560"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4125"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4067"/>
    <dbReference type="OMA" id="IVFYRSD"/>
    <dbReference type="OrthoDB" id="428602at2"/>
    <dbReference type="UniPathway" id="UPA00359">
        <property type="reaction ID" value="UER00478"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008759">
        <property type="term" value="F:UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103117">
        <property type="term" value="F:UDP-3-O-acyl-N-acetylglucosamine deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00388">
        <property type="entry name" value="LpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004463">
        <property type="entry name" value="UDP-acyl_GlcNac_deAcase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011334">
        <property type="entry name" value="UDP-acyl_GlcNac_deAcase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015870">
        <property type="entry name" value="UDP-acyl_N-AcGlcN_deAcase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33694">
        <property type="entry name" value="PTHR33694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03331">
        <property type="entry name" value="LpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00325">
        <property type="entry name" value="lpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 12" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="5 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton donor" evidence="12">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN59467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OPD64513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW27619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="303" mass="33302" checksum="AAA60D0C2B7EAAC6" modified="2016-02-17" version="1">MSRQRTLKTVIRATGVGLHSGEKVFLTLRPAPVDTGIVFRRTDLDPVVEMPARADLVTETTLCTGLTYGAGKVMTVEHLLSAMAGLGIDNCYVELSAPEVPIMDGSAGPFVFLLQSAGIAEQDAPKRFIRIKHPVEVRDGDKIARFEPFDGFRLGFTVVFDHPAIPASQSRAQVEFSTQNYIREVSRARTFGFMRDLEYMRERNLGLGGSMDNAIVLDEFRVLNDDGLRYADEFVRHKILDAVGDLYLAGHAIIGAYEGYKSGHALNNKLVRALLAERSSWELVSYPETEAGPVAYGGEAAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLB8</accession>
    <name>A0A0S2DLB8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4044</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59386">
        <property type="protein sequence ID" value="ALN59386"/>
        <property type="gene ID" value="GLE_4044"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4044"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3987"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="40" mass="4500" checksum="B1B6FBFBF57ADE89" modified="2016-02-17" version="1">MDALLDNFSWKFEKVGVQMKSYTDPALVAPDIVEDMPLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLC2</accession>
    <name>A0A0S2DLC2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59372">
        <property type="protein sequence ID" value="ALN59372"/>
        <property type="gene ID" value="GLE_4030"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4030"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3970"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="73" mass="8699" checksum="CEF1C5459233F8C3" modified="2016-02-17" version="1">MIVLDALHECGCLRVDRALSPFRNAVERFLGREFLSIHCVIRREFFWLPMIEARLRKLMQQARWHGKLNPVAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLC6</accession>
    <name>A0A0S2DLC6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Penicillin-binding protein 1B</fullName>
            <shortName evidence="13">PBP-1b</shortName>
            <shortName evidence="13">PBP1b</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Murein polymerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="primary">mrcB</name>
        <name evidence="21" type="ORF">FE772_19490</name>
        <name evidence="20" type="ORF">GLE_3972</name>
    </gene>
    <organism evidence="20 22">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="20 22" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 22">C3</strain>
        </source>
    </reference>
    <reference evidence="21 23" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 23">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 13">Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">In the C-terminal section; belongs to the transpeptidase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">In the N-terminal section; belongs to the glycosyltransferase 51 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948685.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3972"/>
    <dbReference type="EnsemblBacteria" id="ALN59314">
        <property type="protein sequence ID" value="ALN59314"/>
        <property type="gene ID" value="GLE_3972"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3972"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3909"/>
    <dbReference type="OMA" id="VHGMGLA"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009274">
        <property type="term" value="C:peptidoglycan-based cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001264">
        <property type="entry name" value="Glyco_trans_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011813">
        <property type="entry name" value="PBP_1b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036950">
        <property type="entry name" value="PBP_transglycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028166">
        <property type="entry name" value="UB2H"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00912">
        <property type="entry name" value="Transgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14814">
        <property type="entry name" value="UB2H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002799">
        <property type="entry name" value="PBP_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02071">
        <property type="entry name" value="PBP_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="13" id="KW-0133">Cell shape</keyword>
    <keyword evidence="13" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="13" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0808">Transferase</keyword>
    <keyword evidence="16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="UB2H" evidence="19">
        <location>
            <begin position="76"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Transgly" evidence="18">
        <location>
            <begin position="165"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="17">
        <location>
            <begin position="438"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="757"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for transglycosylase activity" evidence="14">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate; for transpeptidase activity" evidence="14">
        <location>
            <position position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR002799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR002799-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF14814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="ALN59314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="QCW27495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="799" mass="86725" checksum="2D252E04242C86A2" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLW9</accession>
    <name>A0A0S2DLW9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_19460</name>
        <name evidence="2" type="ORF">GLE_3967</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948682.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3967"/>
    <dbReference type="EnsemblBacteria" id="ALN59309">
        <property type="protein sequence ID" value="ALN59309"/>
        <property type="gene ID" value="GLE_3967"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3967"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3904"/>
    <dbReference type="OMA" id="YYCGGAH"/>
    <dbReference type="OrthoDB" id="1353168at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242341" evidence="1">
        <location>
            <begin position="22"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="381" mass="42910" checksum="066C4A6897E5C1A8" modified="2016-02-17" version="1">MKSLRLLPLLCCAVLAPLASAAEPAEVWRGTVGALPVAMSLSRGDGAEIYGQYFYLKHLRDLELQGKRDGQGLHLEVRSRDDAVTERWELSEKDGALEGQWRAGKRTLPVRLQRVDAEALRAGRDGERYRRAGDDVSAFDALRIGELNLEKTKTQQFQGHRLQWWREPRTGVELFTVEAGLDEPARARVNRILSQRLWHTAIDALQCTSAANSEFDLTVTPRLFDRRFLSLSLMTSYYCGGAHPDFGDSPLTIDVREGRELALEDVLWLGKGAPPRRTGPGDYDSPGYKRLDQYRESTLVPWTIKTLAGLHPREMMPPKGDDEDGCDYSDPGVWGTSIWYLTPDGLYLGPYFARVARACEYPDWSLVPWKLVEQHPGPALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLY2</accession>
    <name>A0A0S2DLY2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fumarylacetoacetate hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Fumarylacetoacetate hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_20845</name>
        <name evidence="3" type="ORF">GLE_4257</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="QCW27723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948909.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4257"/>
    <dbReference type="EnsemblBacteria" id="ALN59598">
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        <property type="gene ID" value="GLE_4257"/>
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    <dbReference type="KEGG" id="lez:GLE_4257"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4197"/>
    <dbReference type="OMA" id="QLIAHIC"/>
    <dbReference type="OrthoDB" id="775108at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FAA_hydro_N"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
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    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="FAA_hydrolase" evidence="1">
        <location>
            <begin position="82"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="326" mass="35105" checksum="703FB9A3C4B7F3C7" modified="2016-02-17" version="1">MKLGTLKEGGRDGTLIVVARDLSCAVRATGIADTLQRALEDWSNVAPRLNALSDALHEFRADGVFALDFAALASPLPRAYEFVDGSAYLPHVERVRRARGAEVPESFYVDPLMYQAVSAGFYGPRDPVRVPDEAYGIDLEAEVVIVTDDVPMAATPEQAAGHIQLVGLINDVSLRNLIPNELAKGFGFLQSKPRSALSPVFVTPDELGPAWIDSKVHRPLTTHINGEWFGAPEAGVDMQFSFAELVAHAAKTRPLSAGTIVGSGTVANEDTSLGASCFAEKRTVETLEHGKPLTPFMKYGDTVRIEMFDAAGASIFGAIEQRIEKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLY8</accession>
    <name>A0A0S2DLY8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Glyoxalase/bleomycin resistance/dioxygenase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_14875</name>
        <name evidence="4" type="ORF">FE772_19470</name>
        <name evidence="2" type="ORF">GLE_3969</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000038">
        <property type="protein sequence ID" value="OPD63169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948684.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000038.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3969"/>
    <dbReference type="EnsemblBacteria" id="ALN59311">
        <property type="protein sequence ID" value="ALN59311"/>
        <property type="gene ID" value="GLE_3969"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63169">
        <property type="protein sequence ID" value="OPD63169"/>
        <property type="gene ID" value="BV903_14875"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3969"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3906"/>
    <dbReference type="OMA" id="YGKFGWI"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="14"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="135" mass="15272" checksum="9FEEB802B516A403" modified="2016-02-17" version="1">MSEQEPARKPRVHGLGGVFFKARDPAALAQWYQRHLDLDVQGWGGALLRWRRADSGSDAVTVWAPFGEDSEYFKPSDKPYMLNLRVDDLQATLQGLREEGCQVLDRYEESEQGKFGYALDPEGGLLELWQPAPGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLZ3</accession>
    <name>A0A0S2DLZ3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NAD-dependent epimerase/dehydratase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Nucleoside-diphosphate sugar epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_21035</name>
        <name evidence="1" type="ORF">GLE_4298</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948944.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4298"/>
    <dbReference type="EnsemblBacteria" id="ALN59639">
        <property type="protein sequence ID" value="ALN59639"/>
        <property type="gene ID" value="GLE_4298"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4298"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4237"/>
    <dbReference type="OMA" id="MIYGAQG"/>
    <dbReference type="OrthoDB" id="1928091at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="288" mass="31205" checksum="0988746D3FC2B183" modified="2016-02-17" version="1">MKHALVFGGSGQIGLPLLQRLYHDGWRVTAISRGEQTDRPGLHWLRGDLERMPELPKRVDAIFSCGPLLKFAKWYETSGIEASRVVGFGSTSAETKRGSADAEERRVAAELREGEATLFAAAQPRSDAATVLRPTLIYGAGRDATLTRIAQLAQRLRYFPLPRGANGLRQPVHVDDLADAAFAALTAPASFGNTYAVPGGETLSYRDMVARTLACLRPPVKLIELPSPLFNLALLAAQASGRATGLGEAAVRRMRSDMAFDAGPAQRDFGYAPRPFRPSAQMFESPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMC5</accession>
    <name>A0A0S2DMC5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_21285</name>
        <name evidence="3" type="ORF">GLE_4355</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948987.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4355"/>
    <dbReference type="EnsemblBacteria" id="ALN59696">
        <property type="protein sequence ID" value="ALN59696"/>
        <property type="gene ID" value="GLE_4355"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4355"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4294"/>
    <dbReference type="OrthoDB" id="1519144at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242245" evidence="2">
        <location>
            <begin position="27"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="228" mass="25017" checksum="9318361FAA3DEAFD" modified="2016-02-17" version="1">MPHSLKRKFFALTASLATLLGTSVQAQDLAPAWQPRSGDGWVDAWLGDINRYGGRYREPFVDEMVRYYGAPRELVGELLDRRRWTPGDVYYACAIAQVLGRPCRYVVDEWDRDHADGWGAVAQRLGIKPGSADFHKLKRGFVPTYDRWGRPILIDSELRRDFPNRPFRDVETPAPAKASDAKAKDAKAKDAKGGHAAKPGKGPAKPHGGKQAPAKGPAGKGTAGKGQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMN7</accession>
    <name>A0A0S2DMN7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">General secretion pathway protein J</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4177</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4177"/>
    <dbReference type="EnsemblBacteria" id="ALN59519">
        <property type="protein sequence ID" value="ALN59519"/>
        <property type="gene ID" value="GLE_4177"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4177"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4119"/>
    <dbReference type="OMA" id="LPQWEWH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="233" mass="25549" checksum="411F8FC471648CE6" modified="2016-02-17" version="1">MSGVGAGRVAAPRRRAPARRASARGFTLIEVLLAMVLLVAGLALAFATLSAATKTASRGEALAQRSERERAVENFLRRRIAATRPIPFAFDQSTAVPQRFVGEPDRLRFVADLPDYLGQGGPYLHDFAIESDGDQARIVLNLSMVLAGETIKDERPRKPEVLVEGLKSARFRYRTLDPQRGELGEWQEQWQQPEQLPLLVEVTLTDRDGRAWPPLVVSLPLASAAGGGFVPEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNE6</accession>
    <name>A0A0S2DNE6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Endolytic peptidoglycan transglycosylase RlpA</fullName>
            <ecNumber evidence="3">4.2.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 8" type="primary">rlpA</name>
        <name evidence="8" type="ORF">GLE_4482</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the RlpA family.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949089.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4482"/>
    <dbReference type="EnsemblBacteria" id="ALN59823">
        <property type="protein sequence ID" value="ALN59823"/>
        <property type="gene ID" value="GLE_4482"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4482"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4419"/>
    <dbReference type="OrthoDB" id="2027419at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008932">
        <property type="term" value="F:lytic endotransglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042834">
        <property type="term" value="F:peptidoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000270">
        <property type="term" value="P:peptidoglycan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02071">
        <property type="entry name" value="RlpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034718">
        <property type="entry name" value="RlpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009009">
        <property type="entry name" value="RlpA-like_DPBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012997">
        <property type="entry name" value="RplA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007730">
        <property type="entry name" value="SPOR-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036680">
        <property type="entry name" value="SPOR-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03330">
        <property type="entry name" value="DPBB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05036">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110997">
        <property type="entry name" value="SSF110997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="SSF50685"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00413">
        <property type="entry name" value="rlpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51724">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SPOR" evidence="7">
        <location>
            <begin position="481"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="35"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="231"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="406"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="40"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="242"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="561" mass="58061" checksum="D0843EE3E44D774A" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNQ2</accession>
    <name>A0A0S2DNQ2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dgpf domain protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">YciI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_13610</name>
        <name evidence="5" type="ORF">FE772_22975</name>
        <name evidence="3" type="ORF">GLE_4726</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YciI family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000035">
        <property type="protein sequence ID" value="OPD63325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949264.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4726"/>
    <dbReference type="EnsemblBacteria" id="ALN60067">
        <property type="protein sequence ID" value="ALN60067"/>
        <property type="gene ID" value="GLE_4726"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63325">
        <property type="protein sequence ID" value="OPD63325"/>
        <property type="gene ID" value="BV903_13610"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4726"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4660"/>
    <dbReference type="OMA" id="KYLCQVW"/>
    <dbReference type="OrthoDB" id="2051456at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII" evidence="2">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD63325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW28080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="124" mass="13873" checksum="3BBE22E93F4014CF" modified="2016-02-17" version="1">MKFLVMIYNDDALIEALPDGEYATMMRGCIRHADEMRESGQLVDSQMLAPPAQAVSLRTRGGRTTFMDGPFAEAKEYLGGFNLIEAADMDEAVRIAQAFPWSRTGRIEVRPVADFEAVRKHFDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNR2</accession>
    <name>A0A0S2DNR2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Dipeptidyl peptidase IV/S9A/B/C peptidase domain protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">S9 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FE772_23940</name>
        <name evidence="6" type="ORF">GLE_4937</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949427.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4937"/>
    <dbReference type="EnsemblBacteria" id="ALN60278">
        <property type="protein sequence ID" value="ALN60278"/>
        <property type="gene ID" value="GLE_4937"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4937"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4865"/>
    <dbReference type="OMA" id="TDWAHYN"/>
    <dbReference type="OrthoDB" id="821953at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002469">
        <property type="entry name" value="Peptidase_S9B_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00930">
        <property type="entry name" value="DPPIV_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
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        <location>
            <begin position="23"/>
            <end position="793"/>
        </location>
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        <location>
            <begin position="341"/>
            <end position="505"/>
        </location>
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        <location>
            <begin position="597"/>
            <end position="792"/>
        </location>
    </feature>
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        <location>
            <begin position="195"/>
            <end position="219"/>
        </location>
    </feature>
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        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN60278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW28242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="793" mass="88885" checksum="B975F60F08FBD54F" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNW5</accession>
    <name>A0A0S2DNW5_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4856</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_4856"/>
    <dbReference type="EnsemblBacteria" id="ALN60197">
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        <property type="gene ID" value="GLE_4856"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4856"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4786"/>
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    <dbReference type="OrthoDB" id="1846015at2"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
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        <location>
            <begin position="19"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="225" mass="24270" checksum="03FB2A049E7086A9" modified="2016-02-17" version="1">MRVWGLWMLLLAVSGAQAQGKVVIYRCTDAIGQLTVQNNVPCPKGSTQEKRVIEDAPVSAAPPTVITGPGQYPPPAQPMHPPVSSQLPQVARPPQRPAPTAPTPPAPLPKADIADADRLPPPALYECRTYDNGRYLSDTDAPPQRCAPLQTTGLGNVGNGAGVACQMVDDQCQRIPDERLCENWKQRLREAESALRFGRADNRDASAGEYARIQRIVVESTCGTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP16</accession>
    <name>A0A0S2DP16_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-binding response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Response regulator receiver domain</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BV903_11140</name>
        <name evidence="7" type="ORF">FE772_24805</name>
        <name evidence="5" type="ORF">GLE_5118</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000026">
        <property type="protein sequence ID" value="OPD63856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949568.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5118"/>
    <dbReference type="EnsemblBacteria" id="ALN60459">
        <property type="protein sequence ID" value="ALN60459"/>
        <property type="gene ID" value="GLE_5118"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63856">
        <property type="protein sequence ID" value="OPD63856"/>
        <property type="gene ID" value="BV903_11140"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5118"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5043"/>
    <dbReference type="OMA" id="DACEGGR"/>
    <dbReference type="OrthoDB" id="930905at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
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        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="5"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="136"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
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            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD63856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW28392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="201" mass="21708" checksum="BF83E55EB5675966" modified="2016-02-17" version="1">MSEARIYLVDDNDGFRESTAWLLETAGFEVQAYASGPAFLDAYGHERHGGGAQCLVSDIRMPLMSGLQLQEELRRRGIGLPLVFVTAHGDVPLAVEAMRKGAANFLEKPFGDEALIEAIRAAVAHARSHAGGGEAGDDRLARLSPRERQVMDLVVASKPNKIIADVLGISVKTVELHRSNMMNKLGVRSLPELMKVALGHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP79</accession>
    <name>A0A0S2DP79_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hemolysin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_24435</name>
        <name evidence="2" type="ORF">GLE_5041</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949509.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60382">
        <property type="protein sequence ID" value="ALN60382"/>
        <property type="gene ID" value="GLE_5041"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5041"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4969"/>
    <dbReference type="OMA" id="NCWTPRV"/>
    <dbReference type="OrthoDB" id="854284at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="403"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="421" mass="46180" checksum="FBB186C24CC35969" modified="2016-02-17" version="1">MSGLTQQDLNVLGHYARTGNRELYWNYLARHEDSDGYGRLALGVVRNDNAPGRVANIYADTRAREDGRNLRESDWERFGVDLINQDLRRRQMHFNDNRPDLALNLPARDVQRSHDVAFHNARIDPDAWTPRALLEAARNGRGEREVERIWSNMLDNGYFGGPRLGNTIGSIASNMSVWEGGAYTGRLFAARGLATGAHATTDPNTIGGPPLTFSYNERDRSWTQISSGGMMPHVSEVTNPRMLDDLNDARRTRLHRQDLRDDFHPADPNRNRPIMSSPWVVADAGAADRPGQSAVALAAARTGELSPAQCAIHDQCRDGVQRLAAGYGPEGEANLSARLARLAGDQGFRQVDAVLTGGGNAFIVEGNPADPANRNAHVGLREGLETPARDSLQAMAAQGAQPREDATPQQEQQRTAARAMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPE0</accession>
    <name>A0A0S2DPE0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLE_5071</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
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        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN60473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW28405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="521" mass="55766" checksum="78F8A0DDBFCFBF5C" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ38</accession>
    <name>A0A0S2DQ38_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5354</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60695">
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        <property type="gene ID" value="GLE_5354"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5354"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5269"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="44" mass="4942" checksum="A591AE591A23862B" modified="2016-02-17" version="1">MGTVTAGGRTRDRIDRPRSRLRGATVRRSRADYAPPILDSRTQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ66</accession>
    <name>A0A0S2DQ66_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Streptomycin 3''-kinase (Streptomycin 3''-phosphotransferase) (SPH)</fullName>
            <ecNumber evidence="1">2.7.1.87</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5415</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.87" evidence="1"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5415"/>
    <dbReference type="EnsemblBacteria" id="ALN60756">
        <property type="protein sequence ID" value="ALN60756"/>
        <property type="gene ID" value="GLE_5415"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5415"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5331"/>
    <dbReference type="OMA" id="FDFANIF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050299">
        <property type="term" value="F:streptomycin 3''-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR006748">
        <property type="entry name" value="NH2Glyco/OHUrea_AB-resist_kin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04655">
        <property type="entry name" value="APH_6_hur"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="290" mass="32580" checksum="BAF4F8918C9B21B6" modified="2016-02-17" version="1">MPASDSSRYPRFRRHRRSRMTTPYDRHLALWNLSADGAPIHTHSSDLLPVRHEGRPAMLKIAREAEEKRGGLLMNWWDGDGAARVYADDGEGALLLERACGPRSLVQMARNGQDEEATRVLCGAIARLHAPRPQPPPDGLAGLREWFADLPVYAASHGGVLRRCWEVAQELLDDPREVVPLHGDIHHENVLDAGPQRGWIAIDPKRVMGERGFDYANLFTDPDGETALAPGNFERRLAVVCEHARIERRRMLQWIVAFQGLSAAWFLSDAEQPDKEFAIIGKALNELDRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQA0</accession>
    <name>A0A0S2DQA0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5051</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949517.1">
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_5051"/>
    <dbReference type="EnsemblBacteria" id="ALN60392">
        <property type="protein sequence ID" value="ALN60392"/>
        <property type="gene ID" value="GLE_5051"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5051"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4979"/>
    <dbReference type="OMA" id="HIVGCAG"/>
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    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
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    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
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        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="265" mass="27059" checksum="49FF6FC8A3255D64" modified="2016-02-17" version="1">MQGELAGKVAVVHGGSGAIGGAVARAFAREGARVFLAARGRERLDAAVAAIASAGGDAEADCLDALDADAVAAHADRVAERAGRIDIAFNAVGFVHVQGVPFAELSLADFELPVHRYIRSQYAIAQAAARHMGDGGAIVSLVTPVSRMTGPGYLGHCVACAGVEALSRHLAGELGARGIRSVCLRSHVIPETLEHGSHAREVFQPQADAAGVSLDEMMRAAAESTPLRRLPTLDDIAAAAVYAASPRAGAMTGAILNLTSGALVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQD5</accession>
    <name>A0A0S2DQD5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ferredoxin</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">YkgJ family cysteine cluster protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_00230</name>
        <name evidence="1" type="ORF">GLE_5391</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW24325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949772.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5391"/>
    <dbReference type="EnsemblBacteria" id="ALN60732">
        <property type="protein sequence ID" value="ALN60732"/>
        <property type="gene ID" value="GLE_5391"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5391"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5306"/>
    <dbReference type="OMA" id="PCREFEA"/>
    <dbReference type="OrthoDB" id="1677662at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005358">
        <property type="entry name" value="Puta_zinc/iron-chelating_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03692">
        <property type="entry name" value="CxxCxxCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="121" mass="12842" checksum="96E14C377817D919" modified="2016-02-17" version="1">MSDATHPCLRCGACCASFRVAFHWSETDAHPGGLTPATLTEPLDPHRVVMRGTYGGAPVRCGQLRGQVAHDAHCGIYPLRPSPCREVRPAWQDGAPSAQCDKARALHGMAPLTPGDWAATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQQ3</accession>
    <name>A0A0S2DQQ3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5501</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60842">
        <property type="protein sequence ID" value="ALN60842"/>
        <property type="gene ID" value="GLE_5501"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5501"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5416"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045422">
        <property type="entry name" value="DUF6511"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20121">
        <property type="entry name" value="DUF6511"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="50" mass="5540" checksum="87AB42CB5FDC7E45" modified="2016-02-17" version="1">MGFDVPLAQYTQAQATQVIEAVTCAYEASIRHRSNPRVSDDAPFDDPIPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQR7</accession>
    <name>A0A0S2DQR7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5496</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60837">
        <property type="protein sequence ID" value="ALN60837"/>
        <property type="gene ID" value="GLE_5496"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5496"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5411"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="45" mass="5186" checksum="D7393C6F828452F2" modified="2016-02-17" version="1">MVLRPCEFLKSVRYAPFKVAAVVDRRIILEQFGPLRLQIAHGHLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQT9</accession>
    <name>A0A0S2DQT9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_25445</name>
        <name evidence="1" type="ORF">GLE_5259</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949672.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000011.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60600">
        <property type="protein sequence ID" value="ALN60600"/>
        <property type="gene ID" value="GLE_5259"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5259"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5178"/>
    <dbReference type="OMA" id="IYATWRT"/>
    <dbReference type="OrthoDB" id="1886503at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="145" mass="15634" checksum="3F357A3651E00747" modified="2016-02-17" version="1">MAALWLAATAASAATHRVDDSGSQVMNPNVQMRWDANVPGARGRGVAGALEVALRLDVAAWRGRNGRIYMTLPASPSGPLQVAWTTQGRLLPGRLVSGERALVYAGPIGEDALRDRLRLDLQADGQRLDRAQTLTFSFEIDLDEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAB1</accession>
    <name>A0A0S2DAB1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55494">
        <property type="protein sequence ID" value="ALN55494"/>
        <property type="gene ID" value="GLE_0135"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0135"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.138"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="66" mass="7014" checksum="B0FEEF85B93B197A" modified="2016-02-17" version="1">MACAASAAVRASLARELADRWALADPLFAAEIRSLIGLALALCVGVFCVRPIFAAYAVPRADKPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAG6</accession>
    <name>A0A0S2DAG6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CHAD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0143</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945827.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0143"/>
    <dbReference type="EnsemblBacteria" id="ALN55502">
        <property type="protein sequence ID" value="ALN55502"/>
        <property type="gene ID" value="GLE_0143"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0143"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.145"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.40.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007899">
        <property type="entry name" value="CHAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038186">
        <property type="entry name" value="CHAD_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05235">
        <property type="entry name" value="CHAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00880">
        <property type="entry name" value="CHAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51708">
        <property type="entry name" value="CHAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAD" evidence="2">
        <location>
            <begin position="80"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="349" mass="37546" checksum="ED8BF0C8F8E1283E" modified="2016-02-17" version="1">MPQAEVEAVAEGVESAVPPGTPRARRRASRGAAAEEAGAEDAPVRRAGARTPAGSGHGATSRTSDPRPDLRSHTDTAKAARPPGQRLRAHATREIDQALDALGWGGNRIHAGVHLARKNLRRARATLALGADGLGPGAALVDRELRDLNRDLSLLRDAHALVETLDRLLRGELAPDARRLLARARRAAAAARAAAARRAREDDPGLGRRRALLRVLRAALRAMPWAQLQPEHWRAAVAASLQRVARAGERARASGGDEDWHDWRRRARRLSQQQRALKSAGLGADAPTFDKRQIERLGEAQDLNLLLDHCGKGSPFAKAERGALKAFARGELAGARERIQAGSEGRSPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAG8</accession>
    <name>A0A0S2DAG8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CoA transferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">L-carnitine dehydratase/bile acid-inducible protein F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_01815</name>
        <name evidence="1" type="ORF">GLE_0189</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945861.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0189"/>
    <dbReference type="EnsemblBacteria" id="ALN55548">
        <property type="protein sequence ID" value="ALN55548"/>
        <property type="gene ID" value="GLE_0189"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0189"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.191"/>
    <dbReference type="OMA" id="FKIGTME"/>
    <dbReference type="OrthoDB" id="969868at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003673">
        <property type="entry name" value="CoA-Trfase_fam_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044855">
        <property type="entry name" value="CoA-Trfase_III_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023606">
        <property type="entry name" value="CoA-Trfase_III_dom_1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02515">
        <property type="entry name" value="CoA_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89796">
        <property type="entry name" value="SSF89796"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="399" mass="42942" checksum="B5A31811D61CBE92" modified="2016-02-17" version="1">MDSRSSSPTDSRRSGAGPLAGVRVLDLSAYIAGPYGCALLADQGADVIKIEPPDGDNLRQYPSTLASESRAFLGVNRSKRGIVLDLKRAHDHATLLRLVREADVLVHNFRPSVPARLGIDFERLQLINPRLIYCAVSGYGEDGPMKDKAGYDQVLQTLTGMCALQGKRGGPPEIIYGSVVDYYAAALLSGGVASALYERERSGLGQFVGVSLLRSALTMQSARMIWAEGEGLDIGRDMRSGGVTGIHPTREGHIYISANTPRFWQALCEKTGLSELAADPRYDSVRKRAQAAAQIVPRLHAALAARDALEWEALFGDEVPCAAARRIEDMFEHPQVLAEGIVAPIEHPGVGRYRGVAQSIKFGRTPGPAAFAAPQLGQDTEAVKRELDESGTVAARERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAK9</accession>
    <name>A0A0S2DAK9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0203</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55562">
        <property type="protein sequence ID" value="ALN55562"/>
        <property type="gene ID" value="GLE_0203"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0203"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.205"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046116">
        <property type="entry name" value="DUF6053"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19523">
        <property type="entry name" value="DUF6053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="44" mass="4357" checksum="CFBA44EE9C80FBA1" modified="2016-02-17" version="1">MIGLAARAKCRLGDCGRAAARADAAEVTVGGPSGPMLLFQVAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAN1</accession>
    <name>A0A0S2DAN1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Polyamine aminopropyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Putrescine aminopropyltransferase</fullName>
            <shortName evidence="4">PAPT</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Spermidine synthase</fullName>
            <shortName evidence="4">SPDS</shortName>
            <shortName evidence="4">SPDSY</shortName>
            <ecNumber evidence="4">2.5.1.16</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 9" type="primary">speE</name>
        <name evidence="10" type="ORF">FE772_02045</name>
        <name evidence="9" type="ORF">GLE_0243</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 7">
            <text>putrescine + S-adenosyl 3-(methylsulfanyl)propylamine = H(+) + S-methyl-5'-thioadenosine + spermidine</text>
            <dbReference type="Rhea" id="RHEA:12721"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:57443"/>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
            <dbReference type="ChEBI" id="CHEBI:326268"/>
            <dbReference type="EC" id="2.5.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amine and polyamine biosynthesis; spermidine biosynthesis; spermidine from putrescine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer or homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 6">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.16" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945896.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0243"/>
    <dbReference type="EnsemblBacteria" id="ALN55602">
        <property type="protein sequence ID" value="ALN55602"/>
        <property type="gene ID" value="GLE_0243"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0243"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.245"/>
    <dbReference type="OMA" id="HEMVAHP"/>
    <dbReference type="OrthoDB" id="1613081at2"/>
    <dbReference type="UniPathway" id="UPA00248">
        <property type="reaction ID" value="UER00314"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004766">
        <property type="term" value="F:spermidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00198">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030373">
        <property type="entry name" value="PABS_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001045">
        <property type="entry name" value="Spermi_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035246">
        <property type="entry name" value="Spermidine_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037163">
        <property type="entry name" value="Spermidine_synt_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558">
        <property type="entry name" value="PTHR11558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17284">
        <property type="entry name" value="Spermine_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00417">
        <property type="entry name" value="speE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01330">
        <property type="entry name" value="PABS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0745">Spermidine biosynthesis</keyword>
    <keyword evidence="1 4 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PABS" evidence="8">
        <location>
            <begin position="5"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-methyl-5'-thioadenosine binding" evidence="4">
        <location>
            <begin position="141"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Spermidine binding" evidence="4">
        <location>
            <begin position="160"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4 5">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>S-methyl-5'-thioadenosine</name>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>spermidine</name>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>spermidine</name>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>S-methyl-5'-thioadenosine</name>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>S-methyl-5'-thioadenosine</name>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN55602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW24638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="283" mass="31464" checksum="BAC08A1BE188F8ED" modified="2016-02-17" version="1">MTNEAQWHYENFEPTGSSIGYRITRKLDEVQSPFQKIEIFETTDWGNLMLIDGAIMLTTRDNFLYHEMMSHPALFTHAAPKNVVIIGGGDCGTLREVLKHPGVEEAVQCDIDEQVTRMAEKWFPELCDSNGDARAQLLFDDGIAYMANRPAGSVDLIIVDSTDPVGPAEGLFNKAFYDSCFRALREDGILVQQSESPLMLLKLIQEMRTEMGKAGFTTFKTLPFPQPCYPTGWWSCTLARKAGGFDFRQADAQGKGFATKYYNAGIHHGALSTPAFVAQALGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAN8</accession>
    <name>A0A0S2DAN8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0234</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55593">
        <property type="protein sequence ID" value="ALN55593"/>
        <property type="gene ID" value="GLE_0234"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0234"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.236"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="119" mass="12541" checksum="210DB60359EC19B4" modified="2016-02-17" version="1">MGILRGAREWARSVGQRGRPAAVRKFSDRRRGATGALRGWRERRCGVPVEGRATATRGRRSVAGQWRRGAPVGVGATATWGAGRCRGNGDGVALGWPSPGAEGGAVVRSARSRLAPLLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAU2</accession>
    <name>A0A0S2DAU2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_13000</name>
        <name evidence="2" type="ORF">GLE_0261</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000032">
        <property type="protein sequence ID" value="OPD63537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0261"/>
    <dbReference type="EnsemblBacteria" id="ALN55620">
        <property type="protein sequence ID" value="ALN55620"/>
        <property type="gene ID" value="GLE_0261"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63537">
        <property type="protein sequence ID" value="OPD63537"/>
        <property type="gene ID" value="BV903_13000"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0261"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.262"/>
    <dbReference type="OMA" id="ARGWTHE"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="111" mass="12194" checksum="EBE86D1596175ACF" modified="2016-02-17" version="1">MTDIILHNLDPVLSDRLRRVAEARGWSLQRTALHLIETGLFAVEAEMAGRFEDHDSRALQEAIAAMEGIPSDPGFALIGRAEPQDAPAPRPIGPDLSGLELLEEFRPNREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB04</accession>
    <name>A0A0S2DB04_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">C-terminal processing peptidase</fullName>
            <ecNumber evidence="7">3.4.21.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_0275</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase S41A family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55633">
        <property type="protein sequence ID" value="ALN55633"/>
        <property type="gene ID" value="GLE_0275"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0275"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.274"/>
    <dbReference type="OMA" id="TFNQVDW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07560">
        <property type="entry name" value="Peptidase_S41_CPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004447">
        <property type="entry name" value="Peptidase_S41A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00225">
        <property type="entry name" value="prc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
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    <keyword evidence="2 3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
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        <location>
            <begin position="25"/>
            <end position="490"/>
        </location>
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        <location>
            <begin position="142"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="25"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="418"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN55633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="490" mass="51053" checksum="C54BD8CAF448DE11" modified="2016-02-17" version="1">MSLRHPLRSLLPLALALGAVPALAQQPAPPAQATPPAAPVQAPPAASQPASAADDADDADAQDDGQATPPAQAPGKRSAKAGKDDSDSKVPIDEIRRYVAVYNAVKQAYVEPVDDAKLMHSAIRGLLFDLDPHSVYFDKADAENFDEQSRGNYDGIGVELLRQPDGTLRVISPIDDTPAARAGIKAGDLITAIDGKPFKVDEGDSSGPLRGAPGSKVVLTIVREGRDKPFDVTVARETIRVASVKSRMLEPGYGYLRVSAFQADTAADFETQLRKLKEQSGGKLRGLVLDLRSNPGGLLTSAVQIADDLLERGKIVSTRGRIAISDAEFSATPGDLLDGAPLMVLVDAGSASASEVLAGALRDNGRGRVIGSRTFGKGSVQTVLPLDNGDSVKLTTARYYTPSGKSIQALGIVPDVTLRAPKDDKSDRPSYTEAALPGHLHGDEEGQPGSNAGEVLDGDGPIASALAELKTPGATKAAQSAKKPAPAAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB32</accession>
    <name>A0A0S2DB32_LYSEN</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
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        <name evidence="1" type="ORF">GLE_0153</name>
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        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55512">
        <property type="protein sequence ID" value="ALN55512"/>
        <property type="gene ID" value="GLE_0153"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0153"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.155"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="41" mass="4483" checksum="6D68AE3738488EFB" modified="2016-02-17" version="1">MVFASHHCAGLRAGAVFWGIGNRDRLRATAPHLPSSPRRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB41</accession>
    <name>A0A0S2DB41_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF4087 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_10160</name>
        <name evidence="4" type="ORF">FE772_02785</name>
        <name evidence="2" type="ORF">GLE_0398</name>
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    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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        </lineage>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="protein sequence ID" value="QCW24755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946004.1">
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_0398"/>
    <dbReference type="EnsemblBacteria" id="ALN55756">
        <property type="protein sequence ID" value="ALN55756"/>
        <property type="gene ID" value="GLE_0398"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD64068"/>
        <property type="gene ID" value="BV903_10160"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0398"/>
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    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025145">
        <property type="entry name" value="DUF4087"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
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        <location>
            <begin position="23"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="129" mass="14043" checksum="E3BB62494B3BDAA1" modified="2016-02-17" version="1">MSLRTNIAAIAALLLAFGTVVAATPSGAELRCGWFDNPTPGNASLYDRDGEWTIAIQGGYQAKGDWPPEYPPGQWRATNAGRHGYGCACFNVRVDAEEKNILEIFSSKARPLSACRKDPALKGIERRFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB44</accession>
    <name>A0A0S2DB44_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55749">
        <property type="protein sequence ID" value="ALN55749"/>
        <property type="gene ID" value="GLE_0391"/>
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    <dbReference type="KEGG" id="lez:GLE_0391"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0008080">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="21"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="107" mass="12222" checksum="E0521FD41531DFB7" modified="2016-02-17" version="1">MFHDTAKREHLDDLLATFEKMGQAHPREAHWYLPQIGVDPHAQGKGIGAALMRHALARCDQDRALAYLEASKPQNIPFYQHYGFEPLREIQVGAAPPVTPMLRRPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB79</accession>
    <name>A0A0S2DB79_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Type VI secretion system Vgr family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_0436</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
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    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VgrG protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0436"/>
    <dbReference type="EnsemblBacteria" id="ALN55794">
        <property type="protein sequence ID" value="ALN55794"/>
        <property type="gene ID" value="GLE_0436"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0436"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.433"/>
    <dbReference type="OMA" id="FKSQGFD"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006531">
        <property type="entry name" value="Gp5/Vgr_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028244">
        <property type="entry name" value="T6SS_Rhs_Vgr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017847">
        <property type="entry name" value="T6SS_RhsGE_Vgr_subset"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006533">
        <property type="entry name" value="T6SS_Vgr_RhsGE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037026">
        <property type="entry name" value="Vgr_OB-fold_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018769">
        <property type="entry name" value="VgrG2_C_DUF2345"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10106">
        <property type="entry name" value="DUF2345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04717">
        <property type="entry name" value="Phage_base_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13296">
        <property type="entry name" value="T6SS_Vgr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01646">
        <property type="entry name" value="vgr_GE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03361">
        <property type="entry name" value="VI_Rhs_Vgr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage_base_V" evidence="2">
        <location>
            <begin position="462"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="T6SS_Vgr" evidence="4">
        <location>
            <begin position="598"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2345" evidence="3">
        <location>
            <begin position="764"/>
            <end position="923"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN55794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1000" mass="105917" checksum="D46AD88247F07032" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB95</accession>
    <name>A0A0S2DB95_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_02640</name>
        <name evidence="2" type="ORF">GLE_0369</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">YC36</strain>
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            <end position="47"/>
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        <source>
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        <source>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">YC36</strain>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="202" mass="21021" checksum="86E4D9F9529C7C77" modified="2016-02-17" version="1">MKLKSFATLSLSASLSALALLAASLPAAAGSVTVSPAGSTTLAGDATITVMGLDGRLERQVRCALSLSIALAGNGAFSVGAMEFSPQCQDQTGTPFSAVAQNLPQWRGTTSAYDARSAQSALTNPWIVLMEDSGLGPPYYAECRGPSLKGLYWVGLAGGPPTPATRLYTPGNQSIGATSSGRKCYIDLDLRPASYQYFNYRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBR4</accession>
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    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <source>
            <dbReference type="RuleBase" id="RU003357"/>
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        <source>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00965"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN55975.1"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="1016" mass="112683" checksum="A51176208CBC0BF0" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC16</accession>
    <name>A0A0S2DC16_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">GAF domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0717</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0717"/>
    <dbReference type="EnsemblBacteria" id="ALN56075">
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        <property type="gene ID" value="GLE_0717"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0717"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.705"/>
    <dbReference type="OMA" id="DNYIACS"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000614">
        <property type="entry name" value="FRMsr_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01320">
        <property type="entry name" value="UPF0067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GAF" evidence="1">
        <location>
            <begin position="36"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="143" mass="15290" checksum="9280D89C16C70FBE" modified="2016-02-17" version="1">MVEQARALLDGERDRIANAANLSALVNQALPQLNWVGFYFFDGTELVVGPFQGLPACVRIPLDKGVCGAAATRRQTQRVADVHAFPGHIACDAASRSEVVVPLTRGAELIGVFDLDSPIPDRFDADDQAGLEALAQVYVESLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC73</accession>
    <name>A0A0S2DC73_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_04470</name>
        <name evidence="1" type="ORF">GLE_0759</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW25036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946279.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0759"/>
    <dbReference type="EnsemblBacteria" id="ALN56117">
        <property type="protein sequence ID" value="ALN56117"/>
        <property type="gene ID" value="GLE_0759"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0759"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.747"/>
    <dbReference type="OMA" id="NWCATGA"/>
    <dbReference type="OrthoDB" id="1148015at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="252" mass="28090" checksum="C210A248C9237AEE" modified="2016-02-17" version="1">MDAERDLTQAGDWLRPFPDAADVFAADQGHLARHLHPLFSIDLAAVDPQWSGWLHLLSPLEPCDGLVGQYSQVEDGELLKPNWIGFQVEADGRYRLLGDARYFLLESSAQQTPAALAVSRRELETHYAEQEAAYAASRDYYRRHGKLVRLDRKGRPSYGSEDAVELVESVGGEVEAGGNWEETVEFPLEYGRPGGADAGDADEVVWPLSPAGRRFRHVASVPGWNYRTSGADSILLFYEPVERLALLSFDWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCR5</accession>
    <name>A0A0S2DCR5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase, group 1 family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Glycosyltransferase family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_04675</name>
        <name evidence="3" type="ORF">GLE_0799</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946306.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0799"/>
    <dbReference type="EnsemblBacteria" id="ALN56157">
        <property type="protein sequence ID" value="ALN56157"/>
        <property type="gene ID" value="GLE_0799"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0799"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.788"/>
    <dbReference type="OMA" id="HCDDMPA"/>
    <dbReference type="OrthoDB" id="635734at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="16"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="191"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="371" mass="40051" checksum="1B360A51E16D6219" modified="2016-02-17" version="1">MRRLTAMQLLPALESGGVERSTLEIADALVRAGHRAIVVSAGGRLVPRLLQLGAEHIELPIGRKSPSTLLHAFKLRRLMTELGVDLLHLRSRLPAWVGLLAWRGLPDGARPALVTTVHGLNSPSRYSQVMTRGERVICVSDTVRDYVLQHYPDTDPARLRVVPRGIDPAAFPRAPWPDRDARAWAAAQHPQLAGDGPLLLLPGRGTRLKGHADGLQLLADVRADGIDARLWLPGAREPGREDYIEEMQRFAQGLGIADAVAFTAPTDAIARAYAASDLVLQLSRKPEAFGRTVVEALACGRPVLGWNHGGVGELLARLQPRGAVAAFDPLALKRGACELLTHAPAPVDTMAFSLRAMQEATLAVYAELVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCX1</accession>
    <name>A0A0S2DCX1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_05575</name>
        <name evidence="2" type="ORF">GLE_0994</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946449.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56352">
        <property type="protein sequence ID" value="ALN56352"/>
        <property type="gene ID" value="GLE_0994"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0994"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.982"/>
    <dbReference type="OrthoDB" id="2136218at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028962">
        <property type="entry name" value="Imm10"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15588">
        <property type="entry name" value="Imm10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="153" mass="16365" checksum="090501C13ED4541C" modified="2016-02-17" version="1">MRTYPIEEIHSGEDDGCLWVSLGFASEHRPLDVLHIVCALRPDAQDRSLGMAAIYLERDDQSRGGYAGADRIHAGEQAVALELNDHGRRSLEFDAALRLTWADAQAGKRESLAILARMSGYECGRVVECEPAAGAARTSTSSSTGTGTGTTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD58</accession>
    <name>A0A0S2DD58_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1084</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946512.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1084"/>
    <dbReference type="EnsemblBacteria" id="ALN56442">
        <property type="protein sequence ID" value="ALN56442"/>
        <property type="gene ID" value="GLE_1084"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1084"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1071"/>
    <dbReference type="OMA" id="YWLAWPG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="61"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="296" mass="32330" checksum="0F37717B39186C45" modified="2016-02-17" version="1">MSPRGWRPWPRNPWLQRLFVGATLVALGCLAWGFFWEPRQLVERDYDFALPHWSRECEGLRLDVVADLHTGSPHNGLDKLDQIVARLIASDAPAVLMAGDYVILSVLGGTYISADQLAPHLKPLTARKPVYAVLGNHDWWKDGGKVRAALESAGVVVLEDQARKVELGRCTLWIVGIGDKWETRHDIAGAFAGVSDDAPAIALTHNPDLFPEIPPRASLTIAGHTHGGQVQLPWLGTPVVPAQMRYAGGYLVEDGKSLFVSTGIGTSILPVRFGVPPEISRLTLRAAAREPARVTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDI2</accession>
    <name>A0A0S2DDI2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB-dependent siderophore receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLE_1249</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1249"/>
    <dbReference type="EnsemblBacteria" id="ALN56606">
        <property type="protein sequence ID" value="ALN56606"/>
        <property type="gene ID" value="GLE_1249"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1249"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1233"/>
    <dbReference type="OMA" id="TANYVHT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015344">
        <property type="term" value="F:siderophore uptake transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010105">
        <property type="entry name" value="TonB_sidphr_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01783">
        <property type="entry name" value="TonB-siderophor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594860" evidence="7">
        <location>
            <begin position="19"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="51"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="225"/>
            <end position="758"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN56606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="759" mass="82334" checksum="A5B81979FCEB89E7" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDL3</accession>
    <name>A0A0S2DDL3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_06970</name>
        <name evidence="2" type="ORF">GLE_1295</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946667.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1295"/>
    <dbReference type="EnsemblBacteria" id="ALN56652">
        <property type="protein sequence ID" value="ALN56652"/>
        <property type="gene ID" value="GLE_1295"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1295"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1278"/>
    <dbReference type="OrthoDB" id="1532591at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="337" mass="36257" checksum="39497BD6213B08AC" modified="2016-02-17" version="1">MNDPIASLIARLLAERWLSRDDAAVRELLTDAELRNDLDRRLASVGMRLLEHPYAAHIAVGIARPQESAVFGSAKAWSSTNLQLDRDAVALLVVLWALLVLPKRQRQIARQKADRDQDQEQMFAELKPVPVGAEVVEPINERTLMADFGEKLGGKTRIQFNLGSLARQGFIVRRKERIHEGPMLDLAFDYERIAGRVMDGALSFVVAEARQHALEMAEREAADALLESESERATAAELADAALAAAGLQADDYDAFQAAIEAVESVVAADVDADEALPEAVAAETDAVADDGADAAHADASENETADAGGAAADEPAPQDDPVPPEDMKHEEAAADV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDL4</accession>
    <name>A0A0S2DDL4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Rieske 2Fe-2S domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_1173</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1173"/>
    <dbReference type="EnsemblBacteria" id="ALN56531">
        <property type="protein sequence ID" value="ALN56531"/>
        <property type="gene ID" value="GLE_1173"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1173"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1158"/>
    <dbReference type="OMA" id="DRCPHRN"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044043">
        <property type="entry name" value="VanA_C_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19112">
        <property type="entry name" value="VanA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="5">
        <location>
            <begin position="18"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN56531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="343" mass="38194" checksum="8B7B5FE6063CDE61" modified="2016-02-17" version="1">MRDAVRAGGWHPSHAARWFPVLCGERLRAAPVAATLLDRPYALARDGAGRAFALEDRCPHRHAPLSQGRCSDGGLSCPYHGWRFDAQGRLCEIPGMPADAALPQVRVRAAAVREHDGLIWLRPDGRDEGELPAMVRRNPPGSRRFLWQTQWRAHIVDAIENFLDPLHTHWIHPGLVRRGGARRPATARFVPSPQGFAVDYLGQAQQSGLLYRLFESPRESERALFDAPGSAQIEYRYANGGIVRISLHFAPVDAATTSVFASLHVENRWAPAWLVRALVWPLLKRVNDQDARMLALQSDNLRRFGAVRGASTQLDLVRPWVEAFWNHGAPPADAQAKDVALTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDM5</accession>
    <name>A0A0S2DDM5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">HPr kinase/phosphorylase</fullName>
            <shortName evidence="10">HPrK/P</shortName>
            <ecNumber evidence="10">2.7.11.-</ecNumber>
            <ecNumber evidence="10">2.7.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">HPr(Ser) kinase/phosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 13" type="primary">hprK</name>
        <name evidence="14" type="ORF">BV903_16375</name>
        <name evidence="16" type="ORF">D9T17_21180</name>
        <name evidence="15" type="ORF">FE772_06465</name>
        <name evidence="13" type="ORF">GLE_1189</name>
    </gene>
    <organism evidence="13 17">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 17">C3</strain>
        </source>
    </reference>
    <reference evidence="14 18" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 18">B25</strain>
        </source>
    </reference>
    <reference evidence="16 19" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 19">OH11</strain>
        </source>
    </reference>
    <reference evidence="15 20" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 20">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[HPr protein]-L-serine + ATP = [HPr protein]-O-phospho-L-serine + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46600"/>
            <dbReference type="Rhea" id="RHEA-COMP:11602"/>
            <dbReference type="Rhea" id="RHEA-COMP:11603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 10">
            <text>[HPr protein]-O-phospho-L-serine + H(+) + phosphate = [HPr protein]-L-serine + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:46604"/>
            <dbReference type="Rhea" id="RHEA-COMP:11602"/>
            <dbReference type="Rhea" id="RHEA-COMP:11603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homohexamer.</text>
    </comment>
    <comment type="domain">
        <text evidence="10">The Walker A ATP-binding motif also binds Pi and PPi.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="10">Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the HPrK/P family.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="10"/>
    <dbReference type="EC" id="2.7.4.-" evidence="10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000043">
        <property type="protein sequence ID" value="OPD62854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000053">
        <property type="protein sequence ID" value="ROU04955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946583.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000053.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1189"/>
    <dbReference type="EnsemblBacteria" id="ALN56547">
        <property type="protein sequence ID" value="ALN56547"/>
        <property type="gene ID" value="GLE_1189"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62854">
        <property type="protein sequence ID" value="OPD62854"/>
        <property type="gene ID" value="BV903_16375"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1189"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1174"/>
    <dbReference type="OMA" id="AMNNRQK"/>
    <dbReference type="OrthoDB" id="391150at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004712">
        <property type="term" value="F:protein serine/threonine/tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006109">
        <property type="term" value="P:regulation of carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01918">
        <property type="entry name" value="HprK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01249">
        <property type="entry name" value="HPr_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003755">
        <property type="entry name" value="HPr(Ser)_kin/Pase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011104">
        <property type="entry name" value="Hpr_kin/Pase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011126">
        <property type="entry name" value="Hpr_kin/Pase_Hpr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028979">
        <property type="entry name" value="Ser_kin/Pase_Hpr-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30305:SF1">
        <property type="entry name" value="PTHR30305:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07475">
        <property type="entry name" value="Hpr_kinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02603">
        <property type="entry name" value="Hpr_kinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75138">
        <property type="entry name" value="SSF75138"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00679">
        <property type="entry name" value="hpr-ser"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 10" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5 10 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hpr_kinase_N" evidence="11">
        <location>
            <begin position="9"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Hpr_kinase_C" evidence="12">
        <location>
            <begin position="135"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Important for the catalytic mechanism of both phosphorylation and dephosphorylation" evidence="10">
        <location>
            <begin position="206"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Important for the catalytic mechanism of dephosphorylation" evidence="10">
        <location>
            <begin position="272"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for phosphorylation activity. Proton donor; for dephosphorylation activity" evidence="10">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="158"/>
            <end position="165"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN56547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OPD62854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW25356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROU04955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="316" mass="35203" checksum="A563EA785612124D" modified="2016-02-17" version="1">MSKSIRAGELFEQQREKLALRWIAGQRGDGRLVEAVNTVARRPSLAGYLNAIYPNKVQILGTEELTWLDGLDSRLRWETIEKIIQYRPLALVISKDQPCPEDLRIAAEESDTPLWASPRRGHELLNHLQYHLARALAPQITLHGVFMEIYSIGVLITGESGSGKSELALELVTRGHRLVADDAPEFTQIAPDVLDGTCPDMLQDLLEVRGLGVLNIRQMFGDTAVKNNKYLRLIVHLTKPMSEPKATGIERLTGDTSLRRVLDLDVPMITLPVMPGRNLAVLTEAATRLHSLRMKGLDPAAAFIARHSNFLERGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEM4</accession>
    <name>A0A0S2DEM4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF885 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_07520</name>
        <name evidence="2" type="ORF">GLE_1424</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1424"/>
    <dbReference type="EnsemblBacteria" id="ALN56781">
        <property type="protein sequence ID" value="ALN56781"/>
        <property type="gene ID" value="GLE_1424"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1424"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1403"/>
    <dbReference type="OMA" id="VHEAMPG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="PTHR33361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726726" evidence="1">
        <location>
            <begin position="22"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="613" mass="67590" checksum="7292ACF99200A660" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEN2</accession>
    <name>A0A0S2DEN2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA polymerase III subunit gamma/tau</fullName>
            <ecNumber evidence="5">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">dnaX</name>
        <name evidence="8" type="ORF">GLE_1675</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the DnaX/STICHEL family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946967.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1675"/>
    <dbReference type="EnsemblBacteria" id="ALN57031">
        <property type="protein sequence ID" value="ALN57031"/>
        <property type="gene ID" value="GLE_1675"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1675"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1653"/>
    <dbReference type="OMA" id="PGHIVSH"/>
    <dbReference type="OrthoDB" id="556582at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
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        <property type="entry name" value="ClpA/B"/>
    </dbReference>
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        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022754">
        <property type="entry name" value="DNA_pol_III_gamma-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012763">
        <property type="entry name" value="DNA_pol_III_sug/sutau_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045085">
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    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038249">
        <property type="entry name" value="PolIII_tau_V_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12169">
        <property type="entry name" value="DNA_pol3_gamma3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
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    </dbReference>
    <dbReference type="SMART" id="SM00382">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AAA" evidence="7">
        <location>
            <begin position="37"/>
            <end position="188"/>
        </location>
    </feature>
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        <location>
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            <end position="393"/>
        </location>
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        <location>
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            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
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            <begin position="568"/>
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        </location>
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    <evidence type="ECO:0000256" key="1">
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN57031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="746" mass="77539" checksum="E167DEF18DF3BB16" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEN7</accession>
    <name>A0A0S2DEN7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">BV903_13485</name>
        <name evidence="4" type="ORF">FE772_09060</name>
        <name evidence="2" type="ORF">GLE_1760</name>
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        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000034">
        <property type="protein sequence ID" value="OPD63436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947031.1">
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57115">
        <property type="protein sequence ID" value="ALN57115"/>
        <property type="gene ID" value="GLE_1760"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD63436"/>
        <property type="gene ID" value="BV903_13485"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1760"/>
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    <dbReference type="OrthoDB" id="2178638at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594754" evidence="1">
        <location>
            <begin position="34"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="79" mass="8545" checksum="0C11EEA29649EED0" modified="2016-02-17" version="1">MELRLLKAGRRRAHLAALAAAVFGFAASLGATAAVDRCHQCYTDLLLPCQANTPNATPSCWVQYRACLTANRCQIVIEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEV4</accession>
    <name>A0A0S2DEV4_LYSEN</name>
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        <submittedName>
            <fullName evidence="4">Amidohydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Amidohydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_08180</name>
        <name evidence="3" type="ORF">GLE_1569</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW25649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1569"/>
    <dbReference type="EnsemblBacteria" id="ALN56926">
        <property type="protein sequence ID" value="ALN56926"/>
        <property type="gene ID" value="GLE_1569"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1569"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1549"/>
    <dbReference type="OMA" id="GFSIHHE"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
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    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242296" evidence="1">
        <location>
            <begin position="24"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="93"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="503" mass="54477" checksum="C69A2940781AA246" modified="2016-02-17" version="1">MPRTIRLLSLTLPALTLPALACAAGGAHASGRAAAEPVDLLIRHANVVDVIDGKLRADRLIAVRGDRIVAIEPDARAARFQAQRNIDAAGKYAIPGLWDMHVHFGGGDKLIEENKNLLPLYLAHGIAAVRDAAGDLSPSVFEWRDAVAAGRLDGPTIFTSGPKLEGYKSIWPGDIEVGSHEEISKALDQLQGWKADFVKITDNTLSPELFLDALKQARARGFKVSAHVPFVLPIDEVSATGLSSIEHIEYAYKAGSSQEAQISAMVRRGEIDSREGWNRIQATFDRKTALAAYRRLAQRGTAVTPTLNGSFVTTYLDRDDHKQDPYLQYIGPGLQATYAWRVERAAKDDAAAIARRHQRYQRNAAILPLLQQAGVNLLAGTDAGFLNSFNYPGVGLHDEMQRFVESGLSPLQTLRAATINGARFLGQDKEHGSLAAGKAADIVLLDADPLRDIAATRKIDTFVLRGKVYDRAALDALLAGVKQEVAEQRAAQAAAEQAAVPQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFA7</accession>
    <name>A0A0S2DFA7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transporter, major facilitator family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_1865</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947105.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1865"/>
    <dbReference type="EnsemblBacteria" id="ALN57217">
        <property type="protein sequence ID" value="ALN57217"/>
        <property type="gene ID" value="GLE_1865"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1865"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1836"/>
    <dbReference type="OMA" id="WSGFMFA"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Fernandez C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_MTAY01000112.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57149">
        <property type="protein sequence ID" value="ALN57149"/>
        <property type="gene ID" value="GLE_1796"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61128">
        <property type="protein sequence ID" value="OPD61128"/>
        <property type="gene ID" value="BV903_25300"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1796"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1768"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594951" evidence="1">
        <location>
            <begin position="22"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="158" mass="16700" checksum="6D48EF85E815DEB2" modified="2016-02-17" version="1">MNLKRFVLFCALALASHGALASGWTSLGRLNAPTGFPQAGTCDLRVINHYWSSKPIVVPSAVNRYGPTNVQYAFALDLSSLRTFTSNSVALSRFKTAVDAYNATAGAKSLSATLSVGDFPGVSINLSYADAAGLVQGSGWGVAPSELQYYELQESCPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFP7</accession>
    <name>A0A0S2DFP7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_19435</name>
        <name evidence="4" type="ORF">FE772_10260</name>
        <name evidence="2" type="ORF">GLE_2022</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000056">
        <property type="protein sequence ID" value="OPD62233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947219.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000056.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57372">
        <property type="protein sequence ID" value="ALN57372"/>
        <property type="gene ID" value="GLE_2022"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62233">
        <property type="protein sequence ID" value="OPD62233"/>
        <property type="gene ID" value="BV903_19435"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2022"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1987"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595101" evidence="1">
        <location>
            <begin position="26"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="91" mass="9494" checksum="DB0C932A882AD5A7" modified="2016-02-17" version="1">MRTSLRTAVFSALAAASLISGAAVAQGGVRYTETITLYPDENDGDGKLYAALAAKCEAQGLSPSGFVVTSRVHDGYGLVWWHTGEITCVGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG43</accession>
    <name>A0A0S2DG43_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Single-stranded-DNA-specific exonuclease RecJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">recJ</name>
        <name evidence="11" type="ORF">GLE_2242</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RecJ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947393.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2242"/>
    <dbReference type="EnsemblBacteria" id="ALN57591">
        <property type="protein sequence ID" value="ALN57591"/>
        <property type="gene ID" value="GLE_2242"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2242"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2207"/>
    <dbReference type="OMA" id="FIICDHH"/>
    <dbReference type="OrthoDB" id="491634at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008409">
        <property type="term" value="F:5'-3' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004610">
        <property type="entry name" value="RecJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041122">
        <property type="entry name" value="RecJ_OB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17768">
        <property type="entry name" value="RecJ_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00644">
        <property type="entry name" value="recJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 11" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHH" evidence="8">
        <location>
            <begin position="76"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="DHHA1" evidence="9">
        <location>
            <begin position="324"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="RecJ_OB" evidence="10">
        <location>
            <begin position="473"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="317"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN57591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="576" mass="62011" checksum="AD2B14B742C1F2F6" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG59</accession>
    <name>A0A0S2DG59_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Beta-mannosidase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Lysosomal beta A mannosidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">GLE_2273</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2273"/>
    <dbReference type="EnsemblBacteria" id="ALN57622">
        <property type="protein sequence ID" value="ALN57622"/>
        <property type="gene ID" value="GLE_2273"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2273"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2238"/>
    <dbReference type="OMA" id="KRQWKGP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041625">
        <property type="entry name" value="Beta-mannosidase_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006103">
        <property type="entry name" value="Glyco_hydro_2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Glyco_hydro_2_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041447">
        <property type="entry name" value="Mannosidase_ig"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02836">
        <property type="entry name" value="Glyco_hydro_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17753">
        <property type="entry name" value="Ig_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17786">
        <property type="entry name" value="Mannosidase_ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="SSF49303"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10 17" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0964">Secreted</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595116" description="Beta-mannosidase" evidence="12">
        <location>
            <begin position="29"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_2" evidence="13">
        <location>
            <begin position="238"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_2_C" evidence="14">
        <location>
            <begin position="361"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="Mannosidase_ig" evidence="16">
        <location>
            <begin position="712"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="domain" description="Ig_mannosidase" evidence="15">
        <location>
            <begin position="804"/>
            <end position="879"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00032581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF17753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF17786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ALN57622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="881" mass="98816" checksum="8FC5E4F1AEAD9D94" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG66</accession>
    <name>A0A0S2DG66_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_10885</name>
        <name evidence="4" type="ORF">FE772_10015</name>
        <name evidence="2" type="ORF">GLE_1970</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000025">
        <property type="protein sequence ID" value="OPD63903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947178.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57320">
        <property type="protein sequence ID" value="ALN57320"/>
        <property type="gene ID" value="GLE_1970"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63903">
        <property type="protein sequence ID" value="OPD63903"/>
        <property type="gene ID" value="BV903_10885"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1970"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1935"/>
    <dbReference type="OMA" id="ANEGVEN"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
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    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595088" evidence="1">
        <location>
            <begin position="26"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="121" mass="10800" checksum="E62D1360AC1712F6" modified="2016-02-17" version="1">MNFNKALIALALGLALAACSNQKQAEEASADAAAASTEAQAAADTAAAAGDAATADAAAASADAAATAADAAATSADAAANAATPAAADAAADAAAGAADAAKDAAGAAKDAAAPAEEAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG79</accession>
    <name>A0A0S2DG79_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 9">Chorismate synthase</fullName>
            <shortName evidence="8">CS</shortName>
            <ecNumber evidence="4 8 9">4.2.3.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">5-enolpyruvylshikimate-3-phosphate phospholyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">aroC</name>
        <name evidence="11" type="ORF">FE772_10805</name>
        <name evidence="10" type="ORF">GLE_2140</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 9">
            <text>5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21020"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="EC" id="4.2.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8 9">
            <name>FMNH2</name>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
        </cofactor>
        <text evidence="8 9">Reduced FMN (FMNH(2)).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8 9">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 9">Belongs to the chorismate synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.5" evidence="4 8 9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947310.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2140"/>
    <dbReference type="EnsemblBacteria" id="ALN57490">
        <property type="protein sequence ID" value="ALN57490"/>
        <property type="gene ID" value="GLE_2140"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2140"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2104"/>
    <dbReference type="OMA" id="MLSINAV"/>
    <dbReference type="OrthoDB" id="981870at2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004107">
        <property type="term" value="F:chorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07304">
        <property type="entry name" value="Chorismate_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00300">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000453">
        <property type="entry name" value="Chorismate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035904">
        <property type="entry name" value="Chorismate_synth_AroC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020541">
        <property type="entry name" value="Chorismate_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21085">
        <property type="entry name" value="PTHR21085"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01264">
        <property type="entry name" value="Chorismate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001456">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103263">
        <property type="entry name" value="SSF103263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00033">
        <property type="entry name" value="aroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00787">
        <property type="entry name" value="CHORISMATE_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00788">
        <property type="entry name" value="CHORISMATE_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00789">
        <property type="entry name" value="CHORISMATE_SYNTHASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8 9" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0288">FMN</keyword>
    <keyword evidence="7 8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="125"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="238"/>
            <end position="239"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="293"/>
            <end position="297"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN57490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW26086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="370" mass="39571" checksum="80CB331B6E52653E" modified="2016-02-17" version="1">MASNSFGTLLTVTTFGESHGPAIGCVVDGCPPGLELAPEEFRHDLERRATGRSRHTSQRREADEIEILSGVYQGRTTGTPIALLIRNTDARSKDYGNIAEQFRPGHADYSYWQKYGHRDPRGGGRSSARETTMRVAAGVIAKKWLAQRFGVVVRGYVSQIGTIVPAGFDLDAVETNPFFWPHAAQLDELEQYMDALRKSGDSVGARVEVIADGVPPGWGEPIYGKLDGELAAALMSINAVKGVEIGDGFASVASKGTEHRDELLPDGFASNHAGGILGGISTGQRLRCSAAFKPTSSLRLPGRSLDIRGNEIEVVTTGRHDPCVGIRAAPICEAMVALVLMDQALRHRAQCGDVGEVTPRVPAQAGQGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG91</accession>
    <name>A0A0S2DG91_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ATP-dependent Clp protease ATP-binding subunit ClpA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">clpA</name>
        <name evidence="10" type="ORF">FE772_11580</name>
        <name evidence="9" type="ORF">GLE_2305</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947437.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2305"/>
    <dbReference type="EnsemblBacteria" id="ALN57654">
        <property type="protein sequence ID" value="ALN57654"/>
        <property type="gene ID" value="GLE_2305"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2305"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2270"/>
    <dbReference type="OMA" id="GRVIQEH"/>
    <dbReference type="OrthoDB" id="44062at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043335">
        <property type="term" value="P:protein unfolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013461">
        <property type="entry name" value="ClpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02639">
        <property type="entry name" value="ClpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clp R" evidence="8">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN57654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW26214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="759" mass="83182" checksum="6DB6DDF5CF2F9B01" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGB5</accession>
    <name>A0A0S2DGB5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57617">
        <property type="protein sequence ID" value="ALN57617"/>
        <property type="gene ID" value="GLE_2268"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2268"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2233"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="89" mass="8829" checksum="230DEC2750A59595" modified="2016-02-17" version="1">MVAGPSGPVLFFRIGEAGRKASGLKSLPQQQGLGSLHAAGAAAAGRSSAEPAPAAPAPRPPLLRNIPAALRAAVSPARSRQANLGKTNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGN0</accession>
    <name>A0A0S2DGN0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Flavohemoprotein</fullName>
            <ecNumber evidence="6">1.14.12.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Flavohemoglobin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Hemoglobin-like protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Nitric oxide dioxygenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="primary">hmp</name>
        <name evidence="23" type="synonym">hmpA</name>
        <name evidence="23" type="ORF">FE772_11995</name>
        <name evidence="22" type="ORF">GLE_2396</name>
    </gene>
    <organism evidence="22 24">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="22 24" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 24">C3</strain>
        </source>
    </reference>
    <reference evidence="23 25" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 25">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>NADH + 2 nitric oxide + 2 O2 = H(+) + NAD(+) + 2 nitrate</text>
            <dbReference type="Rhea" id="RHEA:19469"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.14.12.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>NADPH + 2 nitric oxide + 2 O2 = H(+) + NADP(+) + 2 nitrate</text>
            <dbReference type="Rhea" id="RHEA:19465"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:17632"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.12.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the globin family. Two-domain flavohemoproteins subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.14.12.17" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947510.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2396"/>
    <dbReference type="EnsemblBacteria" id="ALN57745">
        <property type="protein sequence ID" value="ALN57745"/>
        <property type="gene ID" value="GLE_2396"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2396"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2358"/>
    <dbReference type="OMA" id="ADIHYEV"/>
    <dbReference type="OrthoDB" id="1834577at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008941">
        <property type="term" value="F:nitric oxide dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005344">
        <property type="term" value="F:oxygen carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051409">
        <property type="term" value="P:response to nitrosative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009636">
        <property type="term" value="P:response to toxic substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000971">
        <property type="entry name" value="Globin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023950">
        <property type="entry name" value="Hmp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43396:SF3">
        <property type="entry name" value="PTHR43396:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00042">
        <property type="entry name" value="Globin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01033">
        <property type="entry name" value="GLOBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0216">Detoxification</keyword>
    <keyword evidence="9 18 19" id="KW-0349">Heme</keyword>
    <keyword evidence="12 18" id="KW-0408">Iron</keyword>
    <keyword evidence="10 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-0521">NADP</keyword>
    <keyword evidence="22" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18 19" id="KW-0561">Oxygen transport</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="18 19" id="KW-0813">Transport</keyword>
    <feature type="domain" description="GLOBIN" evidence="20">
        <location>
            <begin position="45"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="21">
        <location>
            <begin position="155"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="binding site" description="distal binding residue" evidence="18">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="proximal binding residue" evidence="18">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00025094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00030024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00030929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00033187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU000356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="ALN57745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="QCW26285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="408" mass="43814" checksum="AAF7771C570A2F4A" modified="2016-02-17" version="1">MSTPLSEATVAVVRATVPALAAHGHAVTTAMYRRLFRDEHIAALFNHANQGGDNAQAHALAGAILAYARNIDDLGALSAALERIAQKHVGYHILPEHYPFVARALLGAIEDVLGDAATPQVLAAWGEAYWLLADLLKRREAELRGELAHAVGGWSGWREFVVAGKRIENAAADAPIASFELRPADGGAVIAHRPGQYLTLRYPVPGQGRIKRNYSISCGPNREAYRITVKREAHGHGGSRHLHDAMAIGERIELTPPAGDFFLPDAPPRPVVLLSGGVGLTPMVSMLEAIAARHPRLQAHYVHGTADGASHVMAAHVQALARAHGAIHVSTFYAQPGAGDALGRSHQREGLIDAEWLRANVPLFESDVYLCGPRPFLRALVPALARAGVADERVHYEFFGPSDERLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGN7</accession>
    <name>A0A0S2DGN7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phospholipase D/transphosphatidylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2073</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Xanthomonadaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947258.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2073"/>
    <dbReference type="EnsemblBacteria" id="ALN57423">
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        <property type="gene ID" value="GLE_2073"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2073"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2038"/>
    <dbReference type="OMA" id="LNVKANH"/>
    <dbReference type="OrthoDB" id="300755at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="term" value="P:organophosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
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        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
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        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="2">
        <location>
            <begin position="225"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="501" mass="54513" checksum="1FD699B972FF3E7A" modified="2016-02-17" version="1">MRHAPALDNDTDPGAAPVRRPRRLRLALALFLLAWIASAVYHVYKPLPPGVGVAGPLRSAREVALLTDLTWTDAQGARHSDQQVFDEALRLIGQARRAIVADQFLFNDFGTENPGEARYRRLSQELTEALVARKRAVPGLTVVLITDPINTVYGSRVSPQLQQLRDAGVEVVITDLARLRTPNPAWSGLWQLCCRWAGSDSDGGWLPNPLGPGKVGLRSWLALLNLNANHRKTLIVDQGEDWTALVASANPHDASSLHGNVALRFSGAAALDLLASERAVAALSGAAWPRALPASVPRESIVDSTSAPRVQVLTEGRIRDALLAAVDGARGGDRLDIAVFYFSHRRLVDAVTAAHKRGVAVRVLLDPNEDAFGRKKNGVPNRQVAAELVAAGVPLRWCDTHGEQCHAKLLLRHGADGKIELIAGSANYTRRNLDDYNLESSARVVALDDAPVARQARTYFERSWSNSDGRIFSADYAKYADDSALRKVWYRIAEASGLSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGX3</accession>
    <name>A0A0S2DGX3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Methyl-accepting chemotaxis protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Methyl-accepting chemotaxis protein (MCP) signaling domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_12265</name>
        <name evidence="7" type="ORF">GLE_2453</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947549.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2453"/>
    <dbReference type="EnsemblBacteria" id="ALN57802">
        <property type="protein sequence ID" value="ALN57802"/>
        <property type="gene ID" value="GLE_2453"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2453"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2416"/>
    <dbReference type="OMA" id="TYDIEQM"/>
    <dbReference type="OrthoDB" id="429006at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024478">
        <property type="entry name" value="HlyB_4HB_MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12729">
        <property type="entry name" value="4HB_MCP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0807">Transducer</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="6">
        <location>
            <begin position="208"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="265"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW26323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="539" mass="58222" checksum="F5271598A291A2E4" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGZ8</accession>
    <name>A0A0S2DGZ8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF5671 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2186</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2186"/>
    <dbReference type="EnsemblBacteria" id="ALN57535">
        <property type="protein sequence ID" value="ALN57535"/>
        <property type="gene ID" value="GLE_2186"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2186"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2148"/>
    <dbReference type="OMA" id="RWLTYLT"/>
    <dbReference type="OrthoDB" id="1922485at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043728">
        <property type="entry name" value="DUF5671"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18920">
        <property type="entry name" value="DUF5671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5671" evidence="2">
        <location>
            <begin position="67"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="215" mass="23816" checksum="F9DBBB12532D5055" modified="2016-02-17" version="1">MAAGLTALERFVHQSLASGHSRQNTAQALVAAGWSEAQVRGALGAYADSDFPVPVPRPRVSVSARETFVYLLTFSALYVVAFHLCDLWFDLIGFYLPDAIEEYPYWNDGVDDSLRSSVAALAVAFPLFAWLCHRIDADVRRNPGHRLSPVRRWLTYLTLFLAAAALICDAAALLYHWLDGELSLRFGLKALAVATIAGSAFGYYMRDLQREETQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH72</accession>
    <name>A0A0S2DH72_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_12220</name>
        <name evidence="1" type="ORF">GLE_2445</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947542.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2445"/>
    <dbReference type="EnsemblBacteria" id="ALN57794">
        <property type="protein sequence ID" value="ALN57794"/>
        <property type="gene ID" value="GLE_2445"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2445"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2408"/>
    <dbReference type="OMA" id="HRWLGEP"/>
    <dbReference type="OrthoDB" id="1869573at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="152" mass="16320" checksum="6EC8D445E24EB296" modified="2016-02-17" version="1">MRIAFDIDGTLTPLGAGQFPAAPLPFPLRLLWREPLREGAAALMRELQADGHEVWVYTSSLRSPAYLRLWLRCAGIRLAGVVNGDAHAQALRGRAVAPSKFPPAFGIDVLVDDAAGVAMEGQTHGFRVVLVAPADRAWADKVRAACRAAPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHF7</accession>
    <name>A0A0S2DHF7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FE772_11765</name>
        <name evidence="9" type="ORF">GLE_2346</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947468.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2346"/>
    <dbReference type="EnsemblBacteria" id="ALN57695">
        <property type="protein sequence ID" value="ALN57695"/>
        <property type="gene ID" value="GLE_2346"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2346"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2308"/>
    <dbReference type="OMA" id="DTVGNRG"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="10"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="139"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="251"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN57695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW26246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="415" mass="45520" checksum="03190E2D0ACE84FC" modified="2016-02-17" version="1">MDFAPSARSQEYLQRLHAFIDRHVAPFDPVYRRENAELNAGADWRGWRVHPRIAELKALAREAGLWNLFLPDAELGAGLSLLEYAPLAEAMGRYEFCAEIFNCNAPDTGNMEVLYHYGSEPQKARWLRPLLDGAIRSVFCMTEPEVASSDATNMRAQIRIEGDEIVVDGRKWWSTGIGHPDARVAIFMGLTDADAAPHARHGMALVPLDAPGVRIERMLPTFGEYDPPYGHGEVSFDNVRLPLDHLIQGPGQGFAIAQGRLGPGRIHHCMRAIGAAERALELLIRRGAGREAFGQPILRLGGNLERVAQARMAIDQARLLTLYAAWKIERFGVKQAMSEISAIKVVAPNMLQEIVDQAIQIHGGAGVSHDTPLTGLFALARALRIADGPDEVHRAMVARVELAKYGIGGKRGAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHM8</accession>
    <name>A0A0S2DHM8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carrier domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2531</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947613.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2531"/>
    <dbReference type="EnsemblBacteria" id="ALN57880">
        <property type="protein sequence ID" value="ALN57880"/>
        <property type="gene ID" value="GLE_2531"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2531"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2493"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="2">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="1">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="93" mass="10149" checksum="C489234A54D59ECA" modified="2016-02-17" version="1">MIREDYLRKVAAAIATVEDNPSLAADIGYSTDIINEVGLDSLKMTDFILGLEDDFGISIDFDKVEYETFTRVDRLIDFLIDATGASAPSPVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHN0</accession>
    <name>A0A0S2DHN0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2520"/>
    <dbReference type="EnsemblBacteria" id="ALN57869">
        <property type="protein sequence ID" value="ALN57869"/>
        <property type="gene ID" value="GLE_2520"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2520"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2483"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595152" evidence="2">
        <location>
            <begin position="46"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="776" mass="85395" checksum="561FB784D38A5528" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHV5</accession>
    <name>A0A0S2DHV5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">M23 peptidase/putative peptidoglycan binding domain protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">RTX toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_13990</name>
        <name evidence="4" type="ORF">GLE_2801</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW26602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2801"/>
    <dbReference type="EnsemblBacteria" id="ALN58149">
        <property type="protein sequence ID" value="ALN58149"/>
        <property type="gene ID" value="GLE_2801"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2801"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2758"/>
    <dbReference type="OrthoDB" id="829328at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M23" evidence="3">
        <location>
            <begin position="33"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="2">
        <location>
            <begin position="174"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="333"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="376" mass="40934" checksum="0A0C4DC56BDF23E6" modified="2016-02-17" version="1">MSYQDVMNTILPPQQGRSPHITGHYGEHRGNGPHGGSDFNYVGGQAGVNLTHPTIHSPVAGTVEFVGGRYGTVTIVDGEGNRHQLLHTQSQSVVVGQRVEPGTAIGTMGGRGPNGEAQYAQHVHYQMKDAQGNNLNPEDFWNRRQHVGGQNTGGHSAAQPAAAGADGVLRQGERGAEVRAMQETLNRLGYRDDQGRPLAADGDFGERSRQAVARFQRENGLREDGVAGPRTLDALREAGPRRDETSLISNPNHPDNRMYRQALEGLERLGPDAGFRTPQDRERAAATLTYEARMSGFKEINHVVQNVNGNGVFAVQGGLNDPAHHRVYADKQQAMNQSVEQTSQRLAQDAPAPKLDQQAQEKQQTQQHQPPRMTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI95</accession>
    <name>A0A0S2DI95_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histidine kinase</fullName>
            <ecNumber evidence="4">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLE_2864</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947870.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2864"/>
    <dbReference type="EnsemblBacteria" id="ALN58212">
        <property type="protein sequence ID" value="ALN58212"/>
        <property type="gene ID" value="GLE_2864"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2864"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2826"/>
    <dbReference type="OMA" id="MVSNHIV"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="14" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="160"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="189"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="235"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="273"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="316"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="370"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="399"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="428"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="12">
        <location>
            <begin position="761"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="13">
        <location>
            <begin position="989"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="727"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="9">
        <location>
            <position position="1038"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN58212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1110" mass="118259" checksum="D762D1EE9712AD27" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIL4</accession>
    <name>A0A0S2DIL4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Molybdopterin biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_2901</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947894.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2901"/>
    <dbReference type="EnsemblBacteria" id="ALN58249">
        <property type="protein sequence ID" value="ALN58249"/>
        <property type="gene ID" value="GLE_2901"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2901"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2863"/>
    <dbReference type="OMA" id="LGSWEVY"/>
    <dbReference type="OrthoDB" id="1408716at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="PTHR10953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="SSF69572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="4">
        <location>
            <begin position="15"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="378" mass="40400" checksum="D35D6CAF7442DBDD" modified="2016-02-17" version="1">MSIEQISPAQARARQQAGAVLIDVREAHERASGQAEHALGVAKDALEADPAATVPDRGAEIVLICQSGARSLRAAQALLDAGYARVASVDGGTTRWIAEGLPLAPLRQSADEIDFYDRYSRHLRLPEVGEAGQRKLQAARVAMVGAGGLGSPAAFYLAAAGVGTLVLADDDVVDRSNLQRQILHTEDRIGTPKVESAKIALQALNPRLRVETFAERITSDNVERLIGEADVVFDGADNFPVRYLLNDACVKLAKPLVYGAIHRFEGQVSLFDAGRHRGQCPCYRCLFPEPPPPEAAPNCAEAGVLGVLPGVIGLVQATEVVKLILGLGESLAGRLLHFDALAMRFRETRLRPDPECPVCAAGRAFPGYIDYQAFCAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIM4</accession>
    <name>A0A0S2DIM4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphomethylpyrimidine kinase</fullName>
            <ecNumber evidence="5">2.7.4.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">thiD</name>
        <name evidence="5" type="ORF">GLE_3189</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ATP = 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + ADP</text>
            <dbReference type="Rhea" id="RHEA:19893"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:58354"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.7"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP = 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23096"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16892"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58354"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; thiamine diphosphate biosynthesis; 4-amino-2-methyl-5-diphosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole: step 3/3.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.7" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948110.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3189"/>
    <dbReference type="EnsemblBacteria" id="ALN58535">
        <property type="protein sequence ID" value="ALN58535"/>
        <property type="gene ID" value="GLE_3189"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3189"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3143"/>
    <dbReference type="OMA" id="DNRHTHG"/>
    <dbReference type="OrthoDB" id="461201at2"/>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00138"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008902">
        <property type="term" value="F:hydroxymethylpyrimidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008972">
        <property type="term" value="F:phosphomethylpyrimidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01169">
        <property type="entry name" value="HMPP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045029">
        <property type="entry name" value="HMP/HMP-P_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004399">
        <property type="entry name" value="HMP/HMP-P_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013749">
        <property type="entry name" value="PM/HMP-P_kinase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20858">
        <property type="entry name" value="PTHR20858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08543">
        <property type="entry name" value="Phos_pyr_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00097">
        <property type="entry name" value="HMP-P_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phos_pyr_kin" evidence="4">
        <location>
            <begin position="20"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="274" mass="28235" checksum="1BC8FBCF55B80347" modified="2016-02-17" version="1">MSATPRTAAIVSALTIAGSDSGGGAGIQADLKTFAAHRVHGLSALAALTAQHTRGVTAVHVPDVGFLRAQIDACFDDFEVRAVKLGMLATAEVIHAVADALEQHKPRWLVLDPVMVATSGARLLEPSALDALRTRLLPLASVVTPNLPEAELLIGAPIADRDAMRAALDGLFALGARAVLLKGGHLPGEGDVVDLFAVPGAPPREIAHPRLQVDAHGTGCTLASAVAANLCLGRSLEDASIAAADYVHLALRQGYKPGRGEVLVLDHFGAAPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ49</accession>
    <name>A0A0S2DJ49_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2964</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58312">
        <property type="protein sequence ID" value="ALN58312"/>
        <property type="gene ID" value="GLE_2964"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2964"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2925"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="49" mass="5076" checksum="2F831993D36BC560" modified="2016-02-17" version="1">MAPGGCGAISRRCGIGSVSGEAGFCRLMWRGSGRIHWDTNIAGAVARLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ59</accession>
    <name>A0A0S2DJ59_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type VI secretion system Vgr family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Type VI secretion system tip protein VgrG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">tssI</name>
        <name evidence="4" type="ORF">FE772_16475</name>
        <name evidence="3" type="ORF">GLE_3331</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VgrG protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948216.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3331"/>
    <dbReference type="EnsemblBacteria" id="ALN58677">
        <property type="protein sequence ID" value="ALN58677"/>
        <property type="gene ID" value="GLE_3331"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3331"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3281"/>
    <dbReference type="OMA" id="IMHAERN"/>
    <dbReference type="OrthoDB" id="1880900at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006531">
        <property type="entry name" value="Gp5/Vgr_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010609">
        <property type="entry name" value="Gp5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017847">
        <property type="entry name" value="T6SS_RhsGE_Vgr_subset"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006533">
        <property type="entry name" value="T6SS_Vgr_RhsGE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037026">
        <property type="entry name" value="Vgr_OB-fold_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06715">
        <property type="entry name" value="Gp5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04717">
        <property type="entry name" value="Phage_base_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01646">
        <property type="entry name" value="vgr_GE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03361">
        <property type="entry name" value="VI_Rhs_Vgr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage_base_V" evidence="2">
        <location>
            <begin position="401"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="731" mass="82868" checksum="4DA1A9A7BA0B2337" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ64</accession>
    <name>A0A0S2DJ64_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_16505</name>
        <name evidence="2" type="ORF">GLE_3337</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3337"/>
    <dbReference type="EnsemblBacteria" id="ALN58683">
        <property type="protein sequence ID" value="ALN58683"/>
        <property type="gene ID" value="GLE_3337"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3337"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3287"/>
    <dbReference type="OMA" id="PWLIQQM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="428" mass="46486" checksum="82580258E50790E4" modified="2016-02-17" version="1">MTADAIPIIVHQHAEDAAFYWRQFQDNALSSQFRPIDLDAIGKLADGNLEGLRVNGDVGWERALAELERWGGAAEAFVCTALAFDAMERRDHSRWQRLRAAADGGECERGMHAACAWLDLAPIRASLEAWLDTETGLERAIALSALASHRRDAGAALASQFDHRDARVRAAAALHAGRLRREDARGPLAALLDDPETAVRREAAYALGLLQDPRAPLALEGLVEPTSALPDPLLALWAVITPRDQVRERIADWLTRADTQANAVQAARYSGDPYWLPRLVEAAAAPGLGGLAADVFCHLTGAAPERDALFPRDPVRVPAHDHDHDADDAPEPADRDSNEEELVFGWDLPVLDVDALAVWLHAHGNDLIAQERLILGQPAHADYALALLNDANQAARHHAALVLAATGAGALFDVTLPLRRQRQALTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ68</accession>
    <name>A0A0S2DJ68_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3198</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58544">
        <property type="protein sequence ID" value="ALN58544"/>
        <property type="gene ID" value="GLE_3198"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3198"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3154"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046116">
        <property type="entry name" value="DUF6053"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19523">
        <property type="entry name" value="DUF6053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="62" mass="6786" checksum="9F35FA24AEDE6CD5" modified="2016-02-17" version="1">MGGPSGPTLCDQIAVAEMQRRKRIRKQAWSSAGARADAVFSRCVAISLRHRDDASRRANNTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK60</accession>
    <name>A0A0S2DK60_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3456</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58801">
        <property type="protein sequence ID" value="ALN58801"/>
        <property type="gene ID" value="GLE_3456"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3456"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3404"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="136" mass="14337" checksum="4D9726154C8B0DBA" modified="2016-02-17" version="1">MGGGRACGAVRPSSAGASWGLIGASGAQSVGAEAHTTRAKASAPIHHPPDRRPRARTSRVRRLRGASVPTRLEPLAAIRIARHPVQALADTRYDPPTACPARRTRTLSRRKAASDRSRSAAAAPARSTARPARKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKC2</accession>
    <name>A0A0S2DKC2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3521</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58865">
        <property type="protein sequence ID" value="ALN58865"/>
        <property type="gene ID" value="GLE_3521"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3521"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3465"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="90" mass="9961" checksum="1002D39BE2CCFACA" modified="2016-02-17" version="1">MLREQTGPPPGPDPRSCNGLPGRQAPSLTTGMGAGPSRRRARRTRLRLTRANSLKCRKTAQNFCASPRAFDDFSFHFNDLSKSSTSAQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKE1</accession>
    <name>A0A0S2DKE1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Probable Fe(2+)-trafficking protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_08865</name>
        <name evidence="4" type="ORF">FE772_17405</name>
        <name evidence="2" type="ORF">GLE_3537</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Fe(2+)-trafficking protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000019">
        <property type="protein sequence ID" value="OPD64285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948364.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3537"/>
    <dbReference type="EnsemblBacteria" id="ALN58881">
        <property type="protein sequence ID" value="ALN58881"/>
        <property type="gene ID" value="GLE_3537"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64285">
        <property type="protein sequence ID" value="OPD64285"/>
        <property type="gene ID" value="BV903_08865"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3537"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3481"/>
    <dbReference type="OMA" id="SKQTMLI"/>
    <dbReference type="OrthoDB" id="2038019at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3880.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00686">
        <property type="entry name" value="Fe_traffic_YggX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007457">
        <property type="entry name" value="Fe_traffick_prot_YggX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036766">
        <property type="entry name" value="Fe_traffick_prot_YggX_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36965">
        <property type="entry name" value="PTHR36965"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04362">
        <property type="entry name" value="Iron_traffic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029827">
        <property type="entry name" value="Fe_traffic_YggX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111148">
        <property type="entry name" value="SSF111148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="89" mass="10051" checksum="DB68900685FD8DAC" modified="2016-02-17" version="1">MSRSVFCQYQQREAEGLDFVPWPGEMGKRIFANIGKAAWAAWLAHQTMLINENRLSPMNPKDRAFLETEMEKFLFGGGADKPAGYVPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKH0</accession>
    <name>A0A0S2DKH0_LYSEN</name>
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        <submittedName>
            <fullName evidence="6">DNA-binding response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BV903_08775</name>
        <name evidence="7" type="ORF">D9T17_10565</name>
        <name evidence="5" type="ORF">GLE_3517</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">OH11</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000019">
        <property type="protein sequence ID" value="OPD64270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000024">
        <property type="protein sequence ID" value="ROU06958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948350.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3517"/>
    <dbReference type="EnsemblBacteria" id="ALN58861">
        <property type="protein sequence ID" value="ALN58861"/>
        <property type="gene ID" value="GLE_3517"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64270">
        <property type="protein sequence ID" value="OPD64270"/>
        <property type="gene ID" value="BV903_08775"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3517"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3461"/>
    <dbReference type="OMA" id="DDPMMQL"/>
    <dbReference type="OrthoDB" id="930905at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
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        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
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        <property type="entry name" value="WalR-like"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="RESPONSE_REGULATORY"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="133"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
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        </source>
    </evidence>
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            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD64270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROU06958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <sequence length="200" mass="21836" checksum="E8B5E29796D35138" modified="2016-02-17" version="1">MIRLLLAEDQALVRGALAALLNLEPDIEVIAEAGDGAQAWEAVKRVQPDVVVTDIEMPGMTGIDLAMRVRDSGMPTRVVIVTTFGRAGYLRRAMDAGVRGYLLKDAPAGQLAEALRQVHRGGRAIDPQLAVAAWSDEDPLTERERQVLRLAGEGLSTAEIGERLHLSQGTVRNYLSEAIGKLDSSNRIEAYRRARQNGWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKK0</accession>
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        <name evidence="10" type="ORF">GLE_3738</name>
    </gene>
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        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3738"/>
    <dbReference type="EnsemblBacteria" id="ALN59082">
        <property type="protein sequence ID" value="ALN59082"/>
        <property type="gene ID" value="GLE_3738"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3738"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3683"/>
    <dbReference type="OMA" id="GLNYRNY"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
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        <property type="project" value="UniProtKB-SubCell"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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        <location>
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        </location>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00023237"/>
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    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW27318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="786" mass="85655" checksum="36A604D64524CF9C" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKT6</accession>
    <name>A0A0S2DKT6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">50S ribosomal protein L5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 10" type="primary">rplE</name>
        <name evidence="12" type="ORF">BV903_22975</name>
        <name evidence="14" type="ORF">D9T17_09490</name>
        <name evidence="13" type="ORF">FE772_18590</name>
        <name evidence="10" type="ORF">GLE_3778</name>
        <name evidence="11" type="ORF">LEN_1365</name>
        <name evidence="15" type="ORF">SAMN05421681_11015</name>
    </gene>
    <organism evidence="10 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 16">C3</strain>
        </source>
    </reference>
    <reference evidence="19" key="2">
        <citation type="journal article" date="2016" name="DNA Res." volume="0" first="0" last="0">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer, Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">M497-1</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="3">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">ATCC 29487</strain>
        </source>
    </reference>
    <reference evidence="11 19" key="4">
        <citation type="journal article" date="2017" name="DNA Res." volume="24" first="169" last="177">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
            <dbReference type="PubMed" id="28065880"/>
            <dbReference type="DOI" id=".1093/dnares/dsw055"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 19">M497-1</strain>
        </source>
    </reference>
    <reference evidence="12 18" key="5">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 18">B25</strain>
        </source>
    </reference>
    <reference evidence="14 20" key="6">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 20">OH11</strain>
        </source>
    </reference>
    <reference evidence="13 21" key="7">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 21">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP014940">
        <property type="protein sequence ID" value="BAV96852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000077">
        <property type="protein sequence ID" value="OPD61605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000023">
        <property type="protein sequence ID" value="ROU07193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNOG01000010">
        <property type="protein sequence ID" value="SDY03313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948545.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3778"/>
    <dbReference type="EnsemblBacteria" id="ALN59122">
        <property type="protein sequence ID" value="ALN59122"/>
        <property type="gene ID" value="GLE_3778"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAV96852">
        <property type="protein sequence ID" value="BAV96852"/>
        <property type="gene ID" value="LEN_1365"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61605">
        <property type="protein sequence ID" value="OPD61605"/>
        <property type="gene ID" value="BV903_22975"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY03313">
        <property type="protein sequence ID" value="SDY03313"/>
        <property type="gene ID" value="SAMN05421681_11015"/>
    </dbReference>
    <dbReference type="KEGG" id="lem:LEN_1365"/>
    <dbReference type="KEGG" id="lez:GLE_3778"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3722"/>
    <dbReference type="OMA" id="ERMYAFL"/>
    <dbReference type="OrthoDB" id="1456375at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000183696">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000218824">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01333_B">
        <property type="entry name" value="Ribosomal_L5_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_L5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020930">
        <property type="entry name" value="Ribosomal_L5_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_L5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020929">
        <property type="entry name" value="Ribosomal_L5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_L5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_L5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="PTHR11994"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002161">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="SSF55282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00358">
        <property type="entry name" value="RIBOSOMAL_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L5" evidence="8">
        <location>
            <begin position="25"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L5_C" evidence="9">
        <location>
            <begin position="85"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAV96852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OPD61605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW27349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ROU07193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="SDY03313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000183696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000218824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="180" mass="20321" checksum="0F6C6F09D1A62404" modified="2016-02-17" version="1">MTTRLEEFYKKEVVPALTEKFGYKNPMEVPRLVKITLNMGVGEAATNKKILENAVADMTKIAGQKPIVTKSRVSVASFKIRDGWPIGAKVTLRRAKMFEFLDRLINISLPRVRDFRGVSGRSFDGRGNYNMGVKEQIIFPEIDFDQVDALRGMDIAITTTAKTDAEAKALLEAFRFPFRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKZ9</accession>
    <name>A0A0S2DKZ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3844</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59187">
        <property type="protein sequence ID" value="ALN59187"/>
        <property type="gene ID" value="GLE_3844"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3844"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3784"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="171" mass="18787" checksum="5BECE4BFA8002587" modified="2016-02-17" version="1">MPSARASRSRRAGGGKRSLHGRKAGPTARRRGSPGSSAEGSATPPRRPRPHVSVRTCRLAAPRRRRDDARRSGRGPSRARPPAVPPRTAHRRSAASPVAGAIARRRFEPRIDLFCRFPRSAGPPAVRARESLATVRRTVTPHRQPVAPRDARPSTPLAFHLARIPLRWRST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL14</accession>
    <name>A0A0S2DL14_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase A</fullName>
            <ecNumber evidence="6">2.1.1.182</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">16S rRNA dimethyladenosine transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">16S rRNA dimethylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">ksgA</name>
        <name evidence="6 10" type="synonym">rsmA</name>
        <name evidence="10" type="ORF">FE772_19215</name>
        <name evidence="9" type="ORF">GLE_3913</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>adenosine(1518)/adenosine(1519) in 16S rRNA + 4 S-adenosyl-L-methionine = 4 H(+) + N(6)-dimethyladenosine(1518)/N(6)-dimethyladenosine(1519) in 16S rRNA + 4 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:19609"/>
            <dbReference type="Rhea" id="RHEA-COMP:10232"/>
            <dbReference type="Rhea" id="RHEA-COMP:10233"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74493"/>
            <dbReference type="EC" id="2.1.1.182"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.182" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948642.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3913"/>
    <dbReference type="EnsemblBacteria" id="ALN59255">
        <property type="protein sequence ID" value="ALN59255"/>
        <property type="gene ID" value="GLE_3913"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3913"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3850"/>
    <dbReference type="OMA" id="KEEEPYF"/>
    <dbReference type="OrthoDB" id="2030110at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052908">
        <property type="term" value="F:16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00607">
        <property type="entry name" value="16SrRNA_methyltr_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023165">
        <property type="entry name" value="rRNA_Ade_diMease-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="PTHR11727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="rADc" evidence="8">
        <location>
            <begin position="30"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN59255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="281" mass="30726" checksum="492F2C27A6BE4AB5" modified="2016-02-17" version="1">MTGTAKTHAKGFKPEAKKHLGQHFLHDANVIAMIVHAVDPKPGDRLVEIGPGQGAITFPLLDRHGELTVIEFDRDLIFPLTETARAHGTLEVIHRDVLTVDFSALAHNGGPIRLVGNLPYNLSSPILFHALEHAAAIRDMHFMLQKEVVDRMAAAPGSKVYGRLSVMLQAYCQVIALFDVPPAAFRPPPKVDSAVVRMIPLAPDRIGIDDHALFARLVRDAFGQRRKTLRNALSLVCDGASIEAAGVRPDARAEQLEVAQFVRLANWLRAHDKVLPDPSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLM5</accession>
    <name>A0A0S2DLM5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="12">General secretion pathway protein D</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="13">Type II secretion system protein GspD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">gspD</name>
        <name evidence="13" type="ORF">BV903_07795</name>
        <name evidence="14" type="ORF">FE772_20465</name>
        <name evidence="12" type="ORF">GLE_4172</name>
    </gene>
    <organism evidence="12 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">C3</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">B25</strain>
        </source>
    </reference>
    <reference evidence="14 17" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cell outer membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial secretin family. GSP D subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000015">
        <property type="protein sequence ID" value="OPD64554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948847.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4172"/>
    <dbReference type="EnsemblBacteria" id="ALN59514">
        <property type="protein sequence ID" value="ALN59514"/>
        <property type="gene ID" value="GLE_4172"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64554">
        <property type="protein sequence ID" value="OPD64554"/>
        <property type="gene ID" value="BV903_07795"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4172"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4114"/>
    <dbReference type="OMA" id="QIQVGDN"/>
    <dbReference type="OrthoDB" id="881521at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.120">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001775">
        <property type="entry name" value="GspD/PilQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005644">
        <property type="entry name" value="NolW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038591">
        <property type="entry name" value="NolW-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004846">
        <property type="entry name" value="T2SS/T3SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013356">
        <property type="entry name" value="T2SS_GspD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004845">
        <property type="entry name" value="T2SS_GspD_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00263">
        <property type="entry name" value="Secretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03958">
        <property type="entry name" value="Secretin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00811">
        <property type="entry name" value="BCTERIALGSPD"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02517">
        <property type="entry name" value="type_II_gspD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00875">
        <property type="entry name" value="T2SP_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Secretin_N" evidence="11">
        <location>
            <begin position="345"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="365"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="388"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN59514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OPD64554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW27657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="753" mass="79594" checksum="8C1D9BD535EFDA7C" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLN7</accession>
    <name>A0A0S2DLN7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Thiol:disulfide interchange protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLE_4188</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the thioredoxin family. DsbC subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057950265.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4188"/>
    <dbReference type="EnsemblBacteria" id="ALN59530">
        <property type="protein sequence ID" value="ALN59530"/>
        <property type="gene ID" value="GLE_4188"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4188"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4130"/>
    <dbReference type="OMA" id="EINRIKW"/>
    <dbReference type="OrthoDB" id="1678187at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd03020">
        <property type="entry name" value="DsbA_DsbC_DsbG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033954">
        <property type="entry name" value="DiS-bond_Isoase_DsbC/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018950">
        <property type="entry name" value="DiS-bond_isomerase_DsbC/G_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009094">
        <property type="entry name" value="DiS-bond_isomerase_DsbC/G_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10411">
        <property type="entry name" value="DsbC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13098">
        <property type="entry name" value="Thioredoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54423">
        <property type="entry name" value="SSF54423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0574">Periplasm</keyword>
    <keyword evidence="5 6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010006469" description="Thiol:disulfide interchange protein" evidence="6">
        <location>
            <begin position="19"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="DsbC_N" evidence="8">
        <location>
            <begin position="60"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin-like_fold" evidence="9">
        <location>
            <begin position="149"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="298" mass="30613" checksum="D9F83CBEA305DF78" modified="2016-02-17" version="1">MKRILLAMLGAASLSACAQAPQGAVANPAEAAKPAVAAAMPATPATPKVAAGSAEARAVAAVRSLNATVAIDKVGPAPMPGFREVVAGSQVVYVSDDGDYLFLPGPGGALFNLRAKRNLTQDTVAGLRRDLLKAIPASERIVFAPASPKYTVTVFTDAECGYCRKLHSEIAEYNRQGIAVEYLAFPRMGLGTEDYKKMVSVWCAADRRKALTEVKAGRDLPARQCPNTVEQQYRIGLQAGVGETGTPTVLTADGVQLGGYVPPARLREALDSLAAEAKGAAKAPPAGGAGPASAAGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLU4</accession>
    <name>A0A0S2DLU4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">ABC transporter, ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BV903_04290</name>
        <name evidence="7" type="ORF">FE772_20635</name>
        <name evidence="5" type="ORF">GLE_4209</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000008">
        <property type="protein sequence ID" value="OPD65146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948872.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000008.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4209"/>
    <dbReference type="EnsemblBacteria" id="ALN59550">
        <property type="protein sequence ID" value="ALN59550"/>
        <property type="gene ID" value="GLE_4209"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65146">
        <property type="protein sequence ID" value="OPD65146"/>
        <property type="gene ID" value="BV903_04290"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4209"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4151"/>
    <dbReference type="OMA" id="GRMPRWR"/>
    <dbReference type="OrthoDB" id="1181903at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="13"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="49"/>
            <end position="56"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD65146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW27684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="252" mass="27842" checksum="AB43975AB8F444A4" modified="2016-02-17" version="1">MAQSHDRPSEPLIRLQALQKVFHTDELETHALSQVSLEIARGDFVAITGPSGCGKSTLLSLLGLLDGADGGQYWLQGRDVTELGNAERARIRNRQIGFIFQSFNLIADLSVEENVELPLTYRDDIDKAQRKRQVREALDLVGMSHRLQHYPGQLSGGQQQRVAVARALAGQPAILLADEPTGNLDSRNGEAVVQLLEQLHRAGATLCMVTHDASFAQRAQRIVHMLDGKIVDEDAFERLRHHYDAMPALAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM65</accession>
    <name>A0A0S2DM65_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mannose-1-phosphate guanylyltransferase</fullName>
            <ecNumber evidence="4">2.7.7.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">manA</name>
        <name evidence="10" type="ORF">BV903_04365</name>
        <name evidence="11" type="ORF">FE772_20715</name>
        <name evidence="9" type="ORF">GLE_4230</name>
    </gene>
    <organism evidence="9 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">C3</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-mannose 1-phosphate + GTP + H(+) = diphosphate + GDP-alpha-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:15229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58409"/>
            <dbReference type="EC" id="2.7.7.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; GDP-alpha-D-mannose from alpha-D-mannose 1-phosphate (GTP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the mannose-6-phosphate isomerase type 2 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.13" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000008">
        <property type="protein sequence ID" value="OPD65159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948886.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000008.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4230"/>
    <dbReference type="EnsemblBacteria" id="ALN59571">
        <property type="protein sequence ID" value="ALN59571"/>
        <property type="gene ID" value="GLE_4230"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65159">
        <property type="protein sequence ID" value="OPD65159"/>
        <property type="gene ID" value="BV903_04365"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4230"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4171"/>
    <dbReference type="OMA" id="ELKKHDP"/>
    <dbReference type="OrthoDB" id="224217at2"/>
    <dbReference type="UniPathway" id="UPA00126">
        <property type="reaction ID" value="UER00930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004475">
        <property type="term" value="F:mannose-1-phosphate guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009298">
        <property type="term" value="P:GDP-mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006375">
        <property type="entry name" value="Man1P_GuaTrfase/Man6P_Isoase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001538">
        <property type="entry name" value="Man6P_isomerase-2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01050">
        <property type="entry name" value="MannoseP_isomer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01479">
        <property type="entry name" value="GMP_PMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="7">
        <location>
            <begin position="4"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="MannoseP_isomer" evidence="8">
        <location>
            <begin position="315"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN59571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD65159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW27699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="470" mass="51624" checksum="6AC424155B359741" modified="2016-02-17" version="1">MLHPVVLSGGSGSRLWPLSRQNQPKQFLSLIGDHSLFQETLLRANALPDTGAPVTVCAEDHRFMVGEQLQGIGVANGAIVLEPSARNTAPAIALAALHLVAEDPAATMLVLPADHLIEDVDAFRDAVARAAVLAEQDWLVTFGITPDYPETGYGYIARGDALGEGGFKVDRFVEKPDLATAESYLAAGTYAWNSGMFLFKAQRYLDELQALAPAILAAARAAYAKANRDLDFIRVGKDEFAASPNDSIDYAVMEKTARAAVVPVSCGWSDIGSWSSLWAVAERDADGNRYEGDVISVDTRDSLVRASDRRMIATIGVEDLVIVDTPDATLVARKDRVQDVKTIVDKLKQAGRQEHLFHRKVYRPWGNYDSIDMGERFQVKRIEVKPGGVLSLQKHHKRAEHWIVVSGVAEVTCDDKVFELRENQSTYIPLGSVHRLRNRGTEPVELIEVQSGSYLGEDDIVRLEDVYGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMA1</accession>
    <name>A0A0S2DMA1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_03410</name>
        <name evidence="2" type="ORF">GLE_4489</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000006">
        <property type="protein sequence ID" value="OPD65348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949095.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000006.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59830">
        <property type="protein sequence ID" value="ALN59830"/>
        <property type="gene ID" value="GLE_4489"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65348">
        <property type="protein sequence ID" value="OPD65348"/>
        <property type="gene ID" value="BV903_03410"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4489"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4426"/>
    <dbReference type="OrthoDB" id="2058087at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594962" evidence="1">
        <location>
            <begin position="25"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD65348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="301" mass="32087" checksum="5DD3A62FBD472325" modified="2016-02-17" version="1">MRYPIYAALPLALLLAACKPAASAADAAAAAKAAPAAPAPAPAAAKAPEATPAPAVAPVAPTPAATVAEPEIAKSFSKDMTYSDLRKRLLGAGWLPLRDPDCRGNVGGEARVCTYLPEVEGCSSDGYCKMWFANRDLGLRVRVGTYGPNDRGNTLGNGTATAVRYWEFVGLDAPVAAACPSRDFDQFLTRFAADPALARQFTAPLVKVVELRSDEDGDVPQPVYVLGSAYRGFNVRYQNGAYHFVYEGQPDKQPLKLNVSKQGANARLVAYRLNMSEGNSYRFEDKGGCWSLTEDPEPPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMF2</accession>
    <name>A0A0S2DMF2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_19580</name>
        <name evidence="2" type="ORF">GLE_3994</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948699.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59336">
        <property type="protein sequence ID" value="ALN59336"/>
        <property type="gene ID" value="GLE_3994"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3994"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3931"/>
    <dbReference type="OrthoDB" id="2017067at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726735" evidence="1">
        <location>
            <begin position="25"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="170" mass="18054" checksum="2CE837939B90448E" modified="2016-02-17" version="1">MRNQIATVALALILGMATISPAQAQEICLPELNPQDSAQNCGGDPGGGGGGGTPGYVLQGVIQNEGYTTEGAVPGGKRLKIRAYSRLADASNDRVDAHYINVRCNAYDPYGPGYTSDYDEENNGALVDVKFASNSVQGEFRTIRVVCTHHARFGFLTYDTTSSAEIVVPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-08-12" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DML8</accession>
    <name>A0A0S2DML8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4399</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59740">
        <property type="protein sequence ID" value="ALN59740"/>
        <property type="gene ID" value="GLE_4399"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4399"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4338"/>
    <dbReference type="OMA" id="YTEQGAF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013538">
        <property type="entry name" value="Activator_of_Hsp90_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08327">
        <property type="entry name" value="AHSA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="151" mass="17184" checksum="6E36B5F5D41B8FAB" modified="2016-02-17" version="1">MQHGEFTIERTYAASPRKLFRAWADPQAKRAWSVCQDGMATIEHRMDFRPGGEEVIVNRGPGDAIHRFHGHYLDIVEDHRIVYGFSMDVDEQRLTASLATVQFLPGDAGTRMVFTEQLAFFDGLQTLQERREGTAVLFDNIALYLHEATAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMU7</accession>
    <name>A0A0S2DMU7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl transferase, group 2 family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_20450</name>
        <name evidence="1" type="ORF">GLE_4170</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4170"/>
    <dbReference type="EnsemblBacteria" id="ALN59512">
        <property type="protein sequence ID" value="ALN59512"/>
        <property type="gene ID" value="GLE_4170"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4170"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4112"/>
    <dbReference type="OMA" id="SWWHGRY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="296" mass="31985" checksum="CAE0D9F6D556736E" modified="2016-02-17" version="1">MSAPGASARAGAAAPFKAVVVSYRSAATIEDCLERLRACDGVGAIRVVDNQSDDGTLDIVQRQASLDPRLRFIANPDNPGFSVGCNQGAADLEPAADGDDWLAFVNPDCMVETDTLRRLHALGAGLGDCLLSADLVNEQGERDAAVRRRDPDFAAMLAGIARPWAAPKMAVAPDDALALQHVQATSGALMLMPRSLFARIGGFDEGYRLHAEDLDLCRRVREAGGVVAVANGVRVVHVRGVSSRSRPFFVEWNKHRGLWRYFRKFEAPRRGALVRAGVFAAIWLRFPIAALRAALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN07</accession>
    <name>A0A0S2DN07_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF11 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_21770</name>
        <name evidence="3" type="ORF">GLE_4460</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949071.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4460"/>
    <dbReference type="EnsemblBacteria" id="ALN59801">
        <property type="protein sequence ID" value="ALN59801"/>
        <property type="gene ID" value="GLE_4460"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4460"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4397"/>
    <dbReference type="OrthoDB" id="474179at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01345">
        <property type="entry name" value="DUF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726683" evidence="1">
        <location>
            <begin position="29"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="domain" description="DUF11" evidence="2">
        <location>
            <begin position="473"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="696" mass="70117" checksum="3F2B9AF184E4BCFC" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN45</accession>
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        <submittedName>
            <fullName evidence="2">Tat (Twin-arginine translocation) pathway signal sequence domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4653</name>
    </gene>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
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            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
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        <location>
            <begin position="32"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="201" mass="22627" checksum="D4C9787B1612077D" modified="2016-02-17" version="1">MHAPRSPSRRRVLRQACAGAAALGLSPLAFAAAGAGAKTLPETDIALPTGDVRDFDFFVGHWTFRNRRLKQRWVGSDDWDEFPASLRCESRMGGVVNLDEGAFPTKGWQGMTVRVFNLAEKRWYLYWINSSTGQLFPPVAGGFDGDRGVFYGDDSDEGRPVKVRFLWTRIDADHARWEQAFSRDGKAWETNWTMEHTRVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN48</accession>
    <name>A0A0S2DN48_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF3297 family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Glutathione peroxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_15970</name>
        <name evidence="4" type="ORF">D9T17_05805</name>
        <name evidence="3" type="ORF">FE772_22935</name>
        <name evidence="1" type="ORF">GLE_4714</name>
    </gene>
    <organism evidence="1 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 5">C3</strain>
        </source>
    </reference>
    <reference evidence="2 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">OH11</strain>
        </source>
    </reference>
    <reference evidence="3 8" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000041">
        <property type="protein sequence ID" value="OPD62966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000018">
        <property type="protein sequence ID" value="ROU08070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949257.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4714"/>
    <dbReference type="EnsemblBacteria" id="ALN60055">
        <property type="protein sequence ID" value="ALN60055"/>
        <property type="gene ID" value="GLE_4714"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62966">
        <property type="protein sequence ID" value="OPD62966"/>
        <property type="gene ID" value="BV903_15970"/>
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    <dbReference type="OMA" id="NVEEYCI"/>
    <dbReference type="OrthoDB" id="1896101at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD62966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROU08070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="84" mass="9443" checksum="D904505E60FC8DDE" modified="2016-02-17" version="1">MTDTPPDRLSNDPRSPFYAPSVLERGIGIRFNGVERSNVEEYCISEGWVRLPVGKSLDRRGNPMTMKHKGAVEAYYLTEAPDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNC8</accession>
    <name>A0A0S2DNC8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-acetylmuramoyl-L-alanine amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4707</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN60048">
        <property type="protein sequence ID" value="ALN60048"/>
        <property type="gene ID" value="GLE_4707"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4707"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4641"/>
    <dbReference type="OrthoDB" id="1584918at2"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
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    </dbReference>
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    </dbReference>
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            <end position="48"/>
        </location>
    </feature>
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        <location>
            <begin position="49"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetylmuramoyl-L-alanine amidase" evidence="2">
        <location>
            <begin position="321"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="660" mass="70600" checksum="F117F6D631C7BB75" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNG4</accession>
    <name>A0A0S2DNG4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Organic hydroperoxide resistance protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">OsmC-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_14060</name>
        <name evidence="4" type="ORF">FE772_22405</name>
        <name evidence="2" type="ORF">GLE_4592</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OsmC/Ohr family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000036">
        <property type="protein sequence ID" value="OPD63258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949168.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000036.1"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN59933">
        <property type="protein sequence ID" value="ALN59933"/>
        <property type="gene ID" value="GLE_4592"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63258">
        <property type="protein sequence ID" value="OPD63258"/>
        <property type="gene ID" value="BV903_14060"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4592"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4527"/>
    <dbReference type="OMA" id="YSACFDS"/>
    <dbReference type="OrthoDB" id="1984062at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019953">
        <property type="entry name" value="OHR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33797">
        <property type="entry name" value="PTHR33797"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03561">
        <property type="entry name" value="organ_hyd_perox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="141" mass="14602" checksum="807DE146D29277CC" modified="2016-02-17" version="1">MSLEKVLYTAHAHVTGGRDGRAVSSDNALDVKLTTPRDLGGAGGDGTNPEQLFAAGYSACFMGAMKFVAGRDKIAFPADASIDGSVGIGPLPTGFGIQAELKISLPGLAREQAQELIEKAHIVCPYSNATRGNIDVTLTLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNN8</accession>
    <name>A0A0S2DNN8_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">Integral membrane protein DUF6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4849</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60190">
        <property type="protein sequence ID" value="ALN60190"/>
        <property type="gene ID" value="GLE_4849"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4849"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4779"/>
    <dbReference type="OMA" id="EINFWTF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="2"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="292" mass="30616" checksum="86EF6E9081337037" modified="2016-02-17" version="1">MAAASVSLALLAVLSRYTRGLAPELVTWGRFVLPVLVLTAFARGPDWRAAWSLADRLGWLRALCAVIAQICFVFAATQGDLLQAVLLYNTGPLFIPLVAWLWLREPLRPATVAGLSLGFLGVLAVLRPGGRALDPLALVALTGGIAMAVSQVLFYRSAQRQPPLRNQFKLYTQASLLSLPLALLGAAHTPWATVLGGGAASEPVWVLTLALLGMTACSLGNQSLRDLAYRGMDNASTLAPLMYVAVPVSAALDWLLFGRVAAPAALFGAALIVAGAVVALRSGAREAAPTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNT7</accession>
    <name>A0A0S2DNT7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hydrolase, CocE/NonD family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">X-Pro dipeptidyl-peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_24425</name>
        <name evidence="3" type="ORF">GLE_5038</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW28324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949507.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5038"/>
    <dbReference type="EnsemblBacteria" id="ALN60379">
        <property type="protein sequence ID" value="ALN60379"/>
        <property type="gene ID" value="GLE_5038"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5038"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4966"/>
    <dbReference type="OMA" id="FPPNQYA"/>
    <dbReference type="OrthoDB" id="327988at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000383">
        <property type="entry name" value="Xaa-Pro-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013736">
        <property type="entry name" value="Xaa-Pro_dipept_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02129">
        <property type="entry name" value="Peptidase_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08530">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242699" evidence="1">
        <location>
            <begin position="25"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="PepX_C" evidence="2">
        <location>
            <begin position="295"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="527" mass="55127" checksum="563F5509994DCAB8" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP61</accession>
    <name>A0A0S2DP61_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione S-transferase</fullName>
            <ecNumber evidence="4">2.5.1.18</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Thiol:disulfide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_23715</name>
        <name evidence="4" type="ORF">GLE_4883</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
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        <property type="protein sequence ID" value="ALN60224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW28205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949388.1">
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_4883"/>
    <dbReference type="EnsemblBacteria" id="ALN60224">
        <property type="protein sequence ID" value="ALN60224"/>
        <property type="gene ID" value="GLE_4883"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4883"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4814"/>
    <dbReference type="OMA" id="KFFQNQP"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
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        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="90"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW28205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="231" mass="25476" checksum="4AF4413DAE0B253D" modified="2016-02-17" version="1">MIDLHYAATPNGLKLRLYLEETGLAHRIVPVKLSAGEQFAPRFLAMSPNNKIPAILDHAPADGGAPLPVFESGAILLYLARKTGLLWPRGERAQLQATQWLFWQMAGLGPMAGQAGHFRAHAPEAVPYAIDRYTREAARLYGVLDRRLQGREFVAGDELSIADIACYPWVVPHAGLGHDLTATPDLQRWFERIRARPATQRAYAGVEDPYAKPANFTQAERQALFGQGVQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP88</accession>
    <name>A0A0S2DP88_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Isoaspartyl peptidase/L-asparaginase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">L-asparagineamidohydrolase</fullName>
            <ecNumber evidence="5">3.5.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_24535</name>
        <name evidence="5" type="ORF">GLE_5061</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="ALN60700"/>
        <property type="gene ID" value="GLE_5359"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5272"/>
    <dbReference type="KEGG" id="lez:GLE_5359"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5274"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="41" mass="4863" checksum="53DE30B184B283DD" modified="2016-02-17" version="1">MSRDDKPPSKAFVRKRPSYFLLSARQKKVAKEKRLFKVTSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ60</accession>
    <name>A0A0S2DQ60_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">SLC13 family permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">TRAP transporter, DctM-like membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BV903_04825</name>
        <name evidence="11" type="ORF">D9T17_03265</name>
        <name evidence="10" type="ORF">FE772_25675</name>
        <name evidence="8" type="ORF">GLE_5311</name>
    </gene>
    <organism evidence="8 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 12">C3</strain>
        </source>
    </reference>
    <reference evidence="9 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">OH11</strain>
        </source>
    </reference>
    <reference evidence="10 15" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 15">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000009">
        <property type="protein sequence ID" value="OPD65067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000010">
        <property type="protein sequence ID" value="ROU08684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949710.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5311"/>
    <dbReference type="EnsemblBacteria" id="ALN60652">
        <property type="protein sequence ID" value="ALN60652"/>
        <property type="gene ID" value="GLE_5311"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65067">
        <property type="protein sequence ID" value="OPD65067"/>
        <property type="gene ID" value="BV903_04825"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5311"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5229"/>
    <dbReference type="OMA" id="AVQWDVI"/>
    <dbReference type="OrthoDB" id="626718at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="446"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="476"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="507"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="530"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="569"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="7">
        <location>
            <begin position="298"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN60652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD65067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW28532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ROU08684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="598" mass="63487" checksum="1A7592DE03CBC4E9" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ79</accession>
    <name>A0A0S2DQ79_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_25690</name>
        <name evidence="2" type="ORF">GLE_5315</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949713.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5315"/>
    <dbReference type="EnsemblBacteria" id="ALN60656">
        <property type="protein sequence ID" value="ALN60656"/>
        <property type="gene ID" value="GLE_5315"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5315"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5232"/>
    <dbReference type="OrthoDB" id="1893449at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242241" evidence="1">
        <location>
            <begin position="24"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="368" mass="40416" checksum="5436C91177762074" modified="2016-02-17" version="1">MTISLFRIAAVAALFAAPALSQAAPAAPASFDGTWQACQRYDGELWCQSLQLEQRGAQIRGAWNWRASNTGGTNLFKGRVVDGRVEFDPEGCSIGANGCEPRTPSKQPSYLLQCGAELQWGDARMTACNAKIDDGSRYRRVARDQVDTVDFSAQAYFDDGKAHPSFDCAKAKTPVERGICADPAAARTDSAIAHLYAKLLPRFSGEAVKGLREDQRWFVGVRDAAYEQAERGERAKVLREQLDSRLKDLQRIREFPRKGLVGDWNNFAGGLEISRDAQGVYRVRGNAAHPIDGRWVCDADLSGSGSDERVLARAEGDADGTGLQLTRIGNALRVQELDVRGQPHPASEFCGHNGSFDGWYFQSMPRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQC7</accession>
    <name>A0A0S2DQC7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RecBCD enzyme subunit RecC</fullName>
            <ecNumber evidence="6">3.1.11.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Exonuclease V subunit RecC</fullName>
            <shortName evidence="6">ExoV subunit RecC</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Helicase/nuclease RecBCD subunit RecC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">recC</name>
        <name evidence="8" type="ORF">GLE_5232</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Exonucleolytic cleavage (in the presence of ATP) in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides.</text>
            <dbReference type="EC" id="3.1.11.5"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RecC family.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.5" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949651.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5232"/>
    <dbReference type="EnsemblBacteria" id="ALN60573">
        <property type="protein sequence ID" value="ALN60573"/>
        <property type="gene ID" value="GLE_5232"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5232"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5150"/>
    <dbReference type="OMA" id="SFDLMQY"/>
    <dbReference type="OrthoDB" id="1320159at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009338">
        <property type="term" value="C:exodeoxyribonuclease V complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008854">
        <property type="term" value="F:exodeoxyribonuclease V activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
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            <end position="1055"/>
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    <evidence type="ECO:0000256" key="1">
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        <source>
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        <source>
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        <source>
            <dbReference type="Pfam" id="PF17946"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN60573.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
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    </evidence>
    <sequence length="1124" mass="123023" checksum="387E8327C5478CD2" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQD6</accession>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">B25</strain>
        </source>
    </reference>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6 9">YC36</strain>
        </source>
    </reference>
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        <property type="gene ID" value="BV903_04910"/>
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        </location>
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    </evidence>
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            <dbReference type="EMBL" id="OPD65081.1"/>
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    </evidence>
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            <dbReference type="EMBL" id="QCW28548.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="405" mass="44475" checksum="0095FFF22958A70A" modified="2016-02-17" version="1">MSKQPTRRSTTLLAAAIGAVLAFGAVTQVNAQSASERSAQRRAAKESGGKAKPAENQYPNATRTSPEAKASSKGGAKLQKMMDAYDKEKFPEARAQADAIIADTGLNAYERSFAAQIGFQVAYDADDNKAAMDYLKKAIETNGLDNNSHFDRMFVLAQLQLQEDQYAESLATMDRFLNESKSTKPEHLIVKGNALYRLERYADASKVIKQAVDGSPEAKPEWLQLLMATYVENNQGAEAAKIAEQIAAKNPNDKRAQMNVAAVYSQSDMLDKAATVLEKMRAAGQFTEDKDYRQLYSTYLNLDGKEKEAANVINEGLEKGVLKPDYQAYVALAQSYYFSEQANKSIDAYKKAAPLAPDGETYLNLARVLWQEDRIPEAKEAAKQAIAKGVKKPDDAKKILALKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQF1</accession>
    <name>A0A0S2DQF1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">APC family permease</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FE772_00305</name>
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    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949787.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60748">
        <property type="protein sequence ID" value="ALN60748"/>
        <property type="gene ID" value="GLE_5407"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5407"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5322"/>
    <dbReference type="OMA" id="FTWETIL"/>
    <dbReference type="OrthoDB" id="527053at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="210"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="255"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="322"/>
        </location>
    </feature>
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        </location>
    </feature>
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            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="436"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
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    </evidence>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN60748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW24340.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="488" mass="49815" checksum="66050ED92B060043" modified="2016-02-17" version="1">MNDAVSAVAPAASKALHGDAALVRALGPFQLGASIVNIIVGAGIFMLPALLYGRLGAGAPLVFVAGAMAIVPIALCFAAIGSRAAATGGPYTFVGAAFGPFAGFLAGALMWVCNASSSAGVAAALAEQAGNAWAALREPLPRAGFIAAAYAAVFALNAFGVKLGARAIVLLATLKLAPLFLLASVGLLFVDWNQIGVGAWPSWSSLSWSTLSWSALPWSALGSSMVLVVFAYSGMETALVPTGEVRDPARHVPRATLSAIVLVVLLYIGIQLACQGLLGARLAGSGAPVADAAGALWAPAHGALLATAAVSMAGFLMGNLFSSSRLLFALGRDGYLPAAFGRVDARHHVPRTALLAHAGIALALALIGNFETLALISGGAICLLFAAVALAAWRAQARDLRGPGEPFRLPGGAWPMPLLAVAVMAAVLATMSAAQWLAIAVSLLALVGVYAVLALRRRGAGLKERCGRTFRPDALRSGRRYLTQERRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQG6</accession>
    <name>A0A0S2DQG6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hydrolase TatD</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">TatD DNase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tatD</name>
        <name evidence="2" type="ORF">BV903_05045</name>
        <name evidence="3" type="ORF">FE772_00110</name>
        <name evidence="1" type="ORF">GLE_5364</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949750.1">
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    <dbReference type="STRING" id="69.GLE_5364"/>
    <dbReference type="EnsemblBacteria" id="ALN60705">
        <property type="protein sequence ID" value="ALN60705"/>
        <property type="gene ID" value="GLE_5364"/>
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        <property type="protein sequence ID" value="OPD65103"/>
        <property type="gene ID" value="BV903_05045"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5364"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5279"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
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        <source>
            <dbReference type="EMBL" id="ALN60705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD65103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="264" mass="29738" checksum="E364B04E5D84D8D6" modified="2016-02-17" version="1">MQLIDIGANLTHDSFDHDRDAVLQRAREAGVSRMVITGASREHSPKALELARRHPGELFATAGVHPHHASEYTAECDAEMRALLAHDEVVAVGECGLDYFRDFSPRPAQRRAFEMQLQTAADTGKPLFLHQRDAHEDFVAMMKNFDGKIGPAVVHCFTGTREELFAYLDRDWYIGITGWLCDERRGLHLRELVKHIPAQRLMIETDAPYLLPRTVKPAPSHRRNEPMYLAHIVEELARDRGEDAATAAAHSTATATAFFRLPPR</sequence>
</entry>
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    <accession>A0A0S2DQL0</accession>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
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        <source>
            <dbReference type="EMBL" id="ALN60855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="47" mass="5553" checksum="DFEDEDBD0D07BCAD" modified="2016-02-17" version="1">MQNLTCGIKRSLQIVNNRIWIYVNSALPKFKILYLFDKVVDLASRRL</sequence>
</entry>
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    <accession>A0A0S2DQM0</accession>
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        <lineage>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
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    <dbReference type="EMBL" id="CP013140">
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="entry name" value="DUF952"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="157" mass="16556" checksum="DB303167F13056F5" modified="2016-02-17" version="1">MIAIALIASMLAGGDGQDTPADAGAARPTIAYKILTRPERHTLDTSGRFEGSAKDLEDGFVHLSTESQLTRTADLHFAGNDDLFVAAVDLRAAGEQLKWELSPRSGLLFPHLYAVLDKALVTGIAPLRRDDGGRVVLPAQLKAPAAAASPSDDRDPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQP4</accession>
    <name>A0A0S2DQP4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Plasmid/phage primase, P4 family</fullName>
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        <name evidence="2" type="ORF">GLE_5503</name>
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        <lineage>
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            <taxon>Proteobacteria</taxon>
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    </organism>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="279" mass="30104" checksum="7C6EC6D29027D45B" modified="2016-02-17" version="1">MSTWNDFNDAEAASAPAPPASQRDAVRSELLLRLQGVLHDLYPKGKAHRGKFTIGDIHGATGDSLEVALAGDKAGLWNDHATGEGGDVFDLIAQHFGLDARRDFPAVLDRAVQLLGRVPLPAPATRQRRRAEPAMDELGPATARWDYLDADGELIACVYRYDPPEGKQYRPWDAKRRKHQAPTPRPLYNQPGLAAAVEAVLVEGEKSADALIERGFCATTAMNGANAPIDKTDWLPLAGKHVLIWPDKDRPGWEYAMLAAQAAFRAGADSVARAASAGG</sequence>
</entry>
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    <accession>A0A0S2DQQ5</accession>
    <name>A0A0S2DQQ5_LYSEN</name>
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            <fullName evidence="1">Prolyl 4-hydroxylase, alpha subunit</fullName>
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        <name evidence="1" type="ORF">GLE_5480</name>
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    <organism evidence="1 2">
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        <lineage>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
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        <property type="gene ID" value="GLE_5480"/>
    </dbReference>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="87" mass="9256" checksum="5F16B44B6FEFCAB7" modified="2016-02-17" version="1">MVFIVLEGGAFAPGQTSACPYNGNAMVYAMFRGDNPTFAEQDMISLALAAKNTGKQILVYGNGTCSSNIPFGAPNRTEGVKYIELKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQU7</accession>
    <name>A0A0S2DQU7_LYSEN</name>
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        <submittedName>
            <fullName evidence="4">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_00935</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
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    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="GLE_0001"/>
    </dbReference>
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        <property type="gene ID" value="GLE_5539"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0001"/>
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    <dbReference type="PATRIC" id="fig|69.6.peg.1"/>
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    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    </dbReference>
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        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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            <end position="93"/>
        </location>
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        <location>
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        </location>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW24447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="110" mass="12431" checksum="6DEED541753D9F89" modified="2016-02-17" version="1">MPKSPAPPKRRLPRAKSKPPAKKRRSPPSELLKLVGARIREVRLERGYSQDHLAYSIPMDRAYVGLIENGKSAASIITLVKFAIALECEVGDLFPYIEDLKPYADWLDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA70</accession>
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        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">FE772_01415</name>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0095"/>
    <dbReference type="EnsemblBacteria" id="ALN55454">
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    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0095"/>
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    <dbReference type="OMA" id="CASVTAW"/>
    <dbReference type="OrthoDB" id="1538300at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
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        <property type="evidence" value="ECO:0007669"/>
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        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
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        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="171" mass="19041" checksum="69201EE1EF23C50B" modified="2016-02-17" version="1">MMPALARVGLHLRPMAMADAPAWFAYLSLPEAVEHTSWRLDGIETLYPQIAASNPFRADAPALFAIVDDLDELVGTVGFHTVLDAPRGGEIAYNLHPAHWGRGIASEACAAVAQWGLEQRGYRRVEAYALDSNVASQRVLDKCGFRRVRLEPGLRAVRGQPRDFWLYRREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAD6</accession>
    <name>A0A0S2DAD6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <lineage>
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    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ALN55506">
        <property type="protein sequence ID" value="ALN55506"/>
        <property type="gene ID" value="GLE_0147"/>
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        <property type="component" value="Chromosome"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0005509">
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        <property type="project" value="InterPro"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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            <end position="30"/>
        </location>
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        </location>
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            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="125" mass="13729" checksum="EFBF1FCD11F065B4" modified="2016-02-17" version="1">MRLPTFRPSAFARLSSALLALALCALPASAQEVASTGDYLARMDADRDGRVSLLEYQDWLSYAFDAMDANRDGVLDASEQPASGRGARAALTREAHRKTLAERFARQDRNRDGFLDARELASPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAG3</accession>
    <name>A0A0S2DAG3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phage shock protein A</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">PspA/IM30 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_22720</name>
        <name evidence="5" type="ORF">FE772_01790</name>
        <name evidence="3" type="ORF">GLE_0183</name>
    </gene>
    <organism evidence="3 6">
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        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PspA/IM30 family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD61645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW24597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN55542">
        <property type="protein sequence ID" value="ALN55542"/>
        <property type="gene ID" value="GLE_0183"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61645">
        <property type="protein sequence ID" value="OPD61645"/>
        <property type="gene ID" value="BV903_22720"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="entry name" value="PspA_IM30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31088">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04012">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="121"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD61645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW24597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="234" mass="25669" checksum="84D08C8543FAAF7C" modified="2016-02-17" version="1">MGKHNGIWSKLLTSVRAGAQELGEAWADSQALRILDQEIRDCDIELRQSRESLAQLMARHTLAQRGLHEREDKIAEYEGYALKALESDEQGLALEVADKIAALEAAREQEQAHLGQLAASVAELRKSVAMAEGNIRRLKQQLDTVKATESMQRAQAAVAQRYAGPQNRLQTAVDSLARIKLKQAERGARIEAAAELARHENGDALERKLRDAGIMPDGAGAEAVLARLRQKLPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAG7</accession>
    <name>A0A0S2DAG7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_01810</name>
        <name evidence="2" type="ORF">GLE_0188</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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            <end position="244"/>
        </location>
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            <dbReference type="Pfam" id="PF13091"/>
        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
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    </evidence>
    <evidence type="ECO:0000313" key="4">
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="249" mass="27930" checksum="BD9A30A3282D01BB" modified="2016-02-17" version="1">MNTAVYTAANVAIQAASQTPATDFAALDRTLRESVADLSLDNEEKFELRELGARLPADRVRYLRNRAFDLARELMQAQPARTLDALRWLEQVVKTLDAVAEPPTLVSSAFFAPGDACLRKLRELCRSAKRSLDVCVYTISDDRLAEEILACHKRGIAVRVISDNDKKFDDGSDVLRLRELGVPVRVDDSPFHMHHKFALFDGRVLANGSFNWTRSATTSNEENLVVTDDANLVRSFSGHFETLWDKFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAH2</accession>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="STRING" id="69.GLE_0080"/>
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        <property type="gene ID" value="GLE_0080"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
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        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033243117" evidence="2">
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            <begin position="30"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="29"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="134" mass="13252" checksum="F8E78C07213D0104" modified="2016-02-17" version="1">MSAPTVAARRILPALCLAAALPLAMSACAGPRPAAEMPSSAEQSAAAGQAPVEPATPAHPTPPPPRPTCNAEAAKAGAIGKTADAATVERARAAAGGRTVRVLKPGQAITKEYLGGRVNVRVDANNVVVDVGCG</sequence>
</entry>
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    <name>A0A0S2DAW7_LYSEN</name>
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        </submittedName>
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        <name evidence="8" type="ORF">FE772_02295</name>
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    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_0294"/>
    <dbReference type="EnsemblBacteria" id="ALN55652">
        <property type="protein sequence ID" value="ALN55652"/>
        <property type="gene ID" value="GLE_0294"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0294"/>
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    <dbReference type="OMA" id="HRYFAGT"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016653">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006784">
        <property type="term" value="P:heme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="COX15/CtaA_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02628">
        <property type="entry name" value="COX15-CtaA"/>
        <property type="match status" value="2"/>
    </dbReference>
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    <keyword evidence="4" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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        <location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="248"/>
        </location>
    </feature>
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            <end position="325"/>
        </location>
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    </feature>
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        <location>
            <begin position="358"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
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            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN55652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW24674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="387" mass="41288" checksum="468EB8F6ABB96875" modified="2016-02-17" version="1">MSVSSLTGLSSSGLYKNFHRIAWLAVALALCVIVFGAFVRLSNAGLSCPDWPTCYGRAAWPSHADDAVDHVATQIRPVEVHKAWREQFHRMIAGLLGVLVLTLALVSARRRSKGMAQIALASLLVAIAIPLYMKGQHVAASALAIVGEAILIAAAARWSNTDLSRVSALTLAVIIFQALLGMWTVTWLLKPIVVMAHLLGGLLTFSLLVWIAWRATNQPIRLADAPRLRGWIALGIAVLGVQIALGGWTSANYAALACGNDFPTCVGQWWPRHDFGEAFVLWRGIGVDYEGGILDGEARIAIQLAHRIMAGVVFVYLAALTVALLRTPGLRGWATLLGALLLLQVGLGIANVKLGLPLAVAVAHNGGAALLLFALVSLLARLRTPEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBA8</accession>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
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        <name evidence="1" type="ORF">GLE_0471</name>
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    <organism evidence="1 2">
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="GLE_0471"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="47" mass="5099" checksum="02A91F167D6ED311" modified="2016-02-17" version="1">MIGAGLITPRDRQIRGLLVHCHDDSSLWSIIGIQRFGGTGSCRFPCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBD9</accession>
    <name>A0A0S2DBD9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0460</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55818">
        <property type="protein sequence ID" value="ALN55818"/>
        <property type="gene ID" value="GLE_0460"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0460"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="45" mass="4848" checksum="13E1AAFF6ECFCDD1" modified="2016-02-17" version="1">MLASMLRQSGPASPLALEQPDAAISIGMRSQPHPFKRQSGRKDGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBG6</accession>
    <name>A0A0S2DBG6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0521</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="ALN55879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="242" mass="26269" checksum="69AE38F3D83B0C95" modified="2016-02-17" version="1">MEASRRAAVRGPTFIRLLARLADADAAPDAQPLSDRLSQWIEWTQTLALSAALDGAPAVAGFGAAGTVQAEAQECARVRRMLAAAIDGDRAFAPPRAGAAIAGARSAAAVEDAGDYPFFRQRYLVLQQTLEAGAGRLRERLRERLTVASPELARLAALDAVMERALGRRERSLLGAAPALLGRRFERLRERAQDAADGGEPDRETWLPRFRDDMREALHAELDLRLQPAQGLLDALRARAND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBM7</accession>
    <name>A0A0S2DBM7_LYSEN</name>
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        <submittedName>
            <fullName evidence="6">Type VI secretion protein IcmF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">icmF</name>
        <name evidence="6" type="ORF">GLE_0431</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="69.GLE_0431"/>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="IcmF-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025743">
        <property type="entry name" value="IcmF-related_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010623">
        <property type="entry name" value="IcmF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017731">
        <property type="entry name" value="TssM1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06761">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14331">
        <property type="entry name" value="IcmF-related_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06744">
        <property type="entry name" value="IcmF_C"/>
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    </dbReference>
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        <property type="entry name" value="SSF52540"/>
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    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03348">
        <property type="entry name" value="VI_IcmF"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
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        <location>
            <begin position="36"/>
            <end position="57"/>
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            <end position="442"/>
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            <end position="837"/>
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            <end position="1205"/>
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        <location>
            <begin position="1243"/>
            <end position="1267"/>
        </location>
    </feature>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN55789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1267" mass="139172" checksum="7CCD31C4B9FADA4D" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBP2</accession>
    <name>A0A0S2DBP2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_0587</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946145.1">
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55945">
        <property type="protein sequence ID" value="ALN55945"/>
        <property type="gene ID" value="GLE_0587"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0587"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.580"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022791">
        <property type="entry name" value="L-PG_synthase/AglD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03706">
        <property type="entry name" value="LPG_synthase_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
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    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
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        <location>
            <begin position="160"/>
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        </location>
    </feature>
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        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN55945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="313" mass="32902" checksum="C5E84F3BF3D0CD51" modified="2016-02-17" version="1">MRSPEPASGGWRRAARRGGRAAGWLLGLAALALVAQQAWARRAQWQPLWQRLDAADIALALALCLAMQLAFGLAWHLFAHGRWVRAQAYADLLRWGQSLPAKYLPGKIWQGVARSALYAGERRAALTFVLFVREQLLSLGIGAAIAALVAPAALSPRAGLALQFALLAFAVAVSAAALWRRVPAVVAARLPAALAGWNEGLPARAVLARVWLLQWLAYAAMCAAFAVLVRGFGLELDLARSSAALCLAGLAGVLAVLVPAGLGVREAGLFWCLAPLVGAGNAAMLALAWRLAITAGEAAFAAASFALGALRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBP3</accession>
    <name>A0A0S2DBP3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">M23 family metallopeptidase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">M23 peptidase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_03570</name>
        <name evidence="4" type="ORF">GLE_0572</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0572"/>
    <dbReference type="EnsemblBacteria" id="ALN55930">
        <property type="protein sequence ID" value="ALN55930"/>
        <property type="gene ID" value="GLE_0572"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0572"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.565"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
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        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
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        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242115" evidence="2">
        <location>
            <begin position="44"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="3">
        <location>
            <begin position="169"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN55930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW24887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="404" mass="43599" checksum="F87B9BC3BF623579" modified="2016-02-17" version="1">MLRKNRMPEHHRASNNTNARRARGAPALYLALALAASSLPASAADDAAPRDVSGTAPDASAGGAYAVAEHGEHLSPQFRQRAWNDIRDNARKLKLAAAPRSSARSLGGLAWPLALNNGLADPGYHAISNYVDQAGAGQVLDYSCGARSYDGHRGTDYYLWPFSWYKMDNNQVKVIAAAAGTIVGRYDGNFDRSCSVNNNNWNAVYVQHADGSVAWYGHMKNGSVTAKGVGASVAQGEYLGIVGSSGSSTEPHLHFEVYDANANLIDPYAGSCNGLNLSSAWAAQRPYYDSAINKLIVGNAQPAFASCPNAESPNENTALRYGQQASFSAFYRDQLNGQQSQYRILRPNGTVFASWTHNGPAPHYASSWWNWTWSSFAPSGPAGIWRFEVAYNGTTYSKNFTLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBW8</accession>
    <name>A0A0S2DBW8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_0593</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
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    <dbReference type="EnsemblBacteria" id="ALN55951">
        <property type="protein sequence ID" value="ALN55951"/>
        <property type="gene ID" value="GLE_0593"/>
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        <property type="term" value="F:protein histidine kinase activity"/>
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        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN55951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="113" mass="11567" checksum="66503662814A0A81" modified="2016-02-17" version="1">MLHELLANPIDNAIRCTPPGGRIEVEARRDGAAVRFAVTDDGPGIAESERERVVERFVRGSKADSQGSGLGLAIAREIAALHGGALTLAASPHPSGLRVSVALPAANAPAARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC37</accession>
    <name>A0A0S2DC37_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bacterioferritin</fullName>
        </submittedName>
        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_22475</name>
        <name evidence="5" type="ORF">D9T17_23540</name>
        <name evidence="4" type="ORF">FE772_04305</name>
        <name evidence="2" type="ORF">GLE_0722</name>
    </gene>
    <organism evidence="2 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">C3</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 9" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD61689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000059">
        <property type="protein sequence ID" value="ROU04545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_RCTY01000059.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0722"/>
    <dbReference type="EnsemblBacteria" id="ALN56080">
        <property type="protein sequence ID" value="ALN56080"/>
        <property type="gene ID" value="GLE_0722"/>
    </dbReference>
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        <property type="gene ID" value="BV903_22475"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="component" value="Chromosome"/>
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    </dbReference>
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        <location>
            <begin position="2"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU04545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="67" mass="7058" checksum="E1FB3556CBA0DBCE" modified="2016-02-17" version="1">MYVCICNGVTDRDIRQAAEAGCRSVSELTMRTGAGANCGSCLDLAGSLLEQARNVRELPLSVLQQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC84</accession>
    <name>A0A0S2DC84_LYSEN</name>
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            <fullName evidence="3">Alpha/beta hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Hydrolase, alpha/beta hydrolase fold family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_04375</name>
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    </gene>
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        <name type="scientific">Lysobacter enzymogenes</name>
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        </lineage>
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    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0737"/>
    <dbReference type="EnsemblBacteria" id="ALN56095">
        <property type="protein sequence ID" value="ALN56095"/>
        <property type="gene ID" value="GLE_0737"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0737"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.725"/>
    <dbReference type="OMA" id="WPYDINA"/>
    <dbReference type="OrthoDB" id="1439833at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
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        <location>
            <begin position="80"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="351" mass="37530" checksum="6507B4DA419A323F" modified="2016-02-17" version="1">MTATPTDRPLDAQRRSLLGGAALALLAGPLGAIGGIAPAFAAAPRKTVAAGPAAWGALKQIDAGVLRVSYAELGPRDGIPVLLLHGWPYDIHTYAEVAPILAGQGYRVIVPYLRGYGATAFRSADTPRNGQQAALAADAIALLDALGIESAIFGGCDWGARTAGIMAALWPQRCKGLVSVSGYLIGNQQAGQTPLSPKAELQWWYQFYFATERGERGYAQNRDEFARLIWELASPQWRFDDATFARSAAAFDNPDHVAIVIHNYRWRLGLAQGEARFDALEAQLAKAPSIVVPTITLEGDANGAPHPPAEAYARKFAGKYQHREITGGIGHNLPQEAPQAFAQAIVDVTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCC0</accession>
    <name>A0A0S2DCC0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0806</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56164">
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        <property type="gene ID" value="GLE_0806"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="51" mass="5495" checksum="9EFE31705012D58C" modified="2016-02-17" version="1">MRAIARESLGDAARERLQTRPKAPLSLASSRARPPSPDPPLSVQRDGAQES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCH8</accession>
    <name>A0A0S2DCH8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Acetylornithine aminotransferase</fullName>
            <shortName evidence="2">ACOAT</shortName>
            <ecNumber evidence="2">2.6.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">astC</name>
        <name evidence="2" type="synonym">argD</name>
        <name evidence="5" type="ORF">BV903_23945</name>
        <name evidence="4" type="ORF">GLE_0870</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">B25</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2-oxoglutarate + N(2)-acetyl-L-ornithine = L-glutamate + N-acetyl-L-glutamate 5-semialdehyde</text>
            <dbReference type="Rhea" id="RHEA:18049"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29123"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
            <dbReference type="EC" id="2.6.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
        <text evidence="2">Binds 1 pyridoxal phosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.11" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000088">
        <property type="protein sequence ID" value="OPD61388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946358.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000088.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0870"/>
    <dbReference type="EnsemblBacteria" id="ALN56228">
        <property type="protein sequence ID" value="ALN56228"/>
        <property type="gene ID" value="GLE_0870"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61388">
        <property type="protein sequence ID" value="OPD61388"/>
        <property type="gene ID" value="BV903_23945"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0870"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.859"/>
    <dbReference type="OMA" id="PFMVPTY"/>
    <dbReference type="OrthoDB" id="572533at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00109"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003992">
        <property type="term" value="F:N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01107">
        <property type="entry name" value="ArgD_aminotrans_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004636">
        <property type="entry name" value="AcOrn/SuccOrn_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00707">
        <property type="entry name" value="argD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="2">
        <location>
            <begin position="106"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="2">
        <location>
            <begin position="226"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>N(2)-acetyl-L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>N(2)-acetyl-L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD61388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="406" mass="43096" checksum="7B5F603B29EF1304" modified="2016-02-17" version="1">MDTASLYALSERYYLPVYRPRRIVLDHGKGSRVWDLDGREYVDFGAGIAVNALGHAHPALVAALTEQAGKLWHTSNVFVSEPPLRLAEQLVSASGFAERVFLCNSGAEANEAAIKLARKWATGEGREPERRVVLSFRGSFHGRTLAAVTATAQPKYHEGFEPLPPGFRYSEFNDLAAAEAAMADGAVCAVLVEPVQGEGGVTPASDAFLRGLRELCDRHGALLILDEIQCGMGRTGELFACHAYQVTPDVVTLAKALGSGFPIGAMLVGPKPAQSMQFGAHGTTFGGNPLAAAVAGAALRELRSPELMANVARQAQAIRAGVAALDAELGLFSEVRGRGLMIGAQLRDEHAGKAGEILDRCVEQGLLLLQAGPDVLRFVPALNIGDADIADGLQRLRAALLQFLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCJ4</accession>
    <name>A0A0S2DCJ4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3 4">Phasin-family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_22455</name>
        <name evidence="5" type="ORF">D9T17_23560</name>
        <name evidence="4" type="ORF">FE772_04285</name>
        <name evidence="2" type="ORF">GLE_0719</name>
    </gene>
    <organism evidence="2 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">C3</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 9" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000075">
        <property type="protein sequence ID" value="OPD61666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000059">
        <property type="protein sequence ID" value="ROU04530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946247.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000059.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0719"/>
    <dbReference type="EnsemblBacteria" id="ALN56077">
        <property type="protein sequence ID" value="ALN56077"/>
        <property type="gene ID" value="GLE_0719"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61666">
        <property type="protein sequence ID" value="OPD61666"/>
        <property type="gene ID" value="BV903_22455"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0719"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.707"/>
    <dbReference type="OMA" id="ENAESMF"/>
    <dbReference type="OrthoDB" id="1836533at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018968">
        <property type="entry name" value="Phasin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09361">
        <property type="entry name" value="Phasin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phasin_2" evidence="1">
        <location>
            <begin position="7"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU04530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="136" mass="14483" checksum="C35520BEF8B49FAB" modified="2016-02-17" version="1">MYQQFNEQFAAATRQFADTAAQVNRLALDNAEAVFGLQIAAIEDRVNATFAFFGEAAEARDFDALKTLFPKGVQVARENVERAVSTGQEAFGRTLKTNEAIAELAKSQVETAAKATQANVEKATKAAAKAAAPAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCQ8</accession>
    <name>A0A0S2DCQ8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Adenylosuccinate lyase</fullName>
            <shortName evidence="10">ASL</shortName>
            <ecNumber evidence="4 10">4.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">Adenylosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">purB</name>
        <name evidence="13" type="ORF">FE772_05115</name>
        <name evidence="12" type="ORF">GLE_0889</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">C3</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + fumarate</text>
            <dbReference type="Rhea" id="RHEA:23920"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:23921"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N(6)-(1,2-dicarboxyethyl)-AMP = AMP + fumarate</text>
            <dbReference type="Rhea" id="RHEA:16853"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:16854"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.2" evidence="4 10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946373.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0889"/>
    <dbReference type="EnsemblBacteria" id="ALN56247">
        <property type="protein sequence ID" value="ALN56247"/>
        <property type="gene ID" value="GLE_0889"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0889"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.878"/>
    <dbReference type="OMA" id="NTPNIGW"/>
    <dbReference type="OrthoDB" id="347727at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00132"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00336"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070626">
        <property type="term" value="F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004018">
        <property type="term" value="F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019468">
        <property type="entry name" value="AdenyloSucc_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004769">
        <property type="entry name" value="Pur_lyase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10397">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00998">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00928">
        <property type="entry name" value="purB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADSL_C" evidence="11">
        <location>
            <begin position="366"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN56247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW25136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="460" mass="50431" checksum="DCFB580398765BCE" modified="2016-02-17" version="1">MPSHVTESRLYGGVYSAPEFAAVFCDRNQLRQWLEVERALALTQAEMGLIPAQAAREIDRAACAEQFDLVALGQENRRTGHILVPTIRALAERCGGGWGEYVHYGVTTQDILDTGLVLQIRQAWALTLARLRSIREHLLALARAHRSTPMVARTHGQQALPTTFGYKVAVWIDEIDRHLQRFDEAHERVMVGNLTGAVGTMAAFGAHGFELQRRTLARLGLGAPRTSWHCARDRILDVAGLLVQVAVTIGRIANEVYHLQRTEIDEVREGAPAGKIGSSTMPHKQNPSTIDLISALSRMIRAQMLALTDAAFHQHERDGTAWRIEWAALPEIFVYAGALLARMDEVLAAGLEIRVERMRSNLDLLGGRLLSERVMLALGERVGKQTAHELVHEASMHARHGDLPFRDALLGDARIRGAFAAQALEDLLDPVTYVGLAADMVDLVAGDGAHDTPGATASGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD03</accession>
    <name>A0A0S2DD03_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56378">
        <property type="protein sequence ID" value="ALN56378"/>
        <property type="gene ID" value="GLE_1020"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1020"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1008"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="53" mass="5883" checksum="AA2C1D8D347369A1" modified="2016-02-17" version="1">MWRTLKGLGGDNRDGGGRLRGRAPDGPQRARTPRPWLRCDARRRAGRATGRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDB7</accession>
    <name>A0A0S2DDB7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 10">RNA polymerase sigma-54 factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">rpoN</name>
        <name evidence="14" type="ORF">GLE_1192</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the sigma-54 factor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1192"/>
    <dbReference type="EnsemblBacteria" id="ALN56550">
        <property type="protein sequence ID" value="ALN56550"/>
        <property type="gene ID" value="GLE_1192"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1192"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1177"/>
    <dbReference type="OMA" id="VTTQKFM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001216">
        <property type="term" value="F:DNA-binding transcription activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000394">
        <property type="entry name" value="RNA_pol_sigma_54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007046">
        <property type="entry name" value="RNA_pol_sigma_54_core-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007634">
        <property type="entry name" value="RNA_pol_sigma_54_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038709">
        <property type="entry name" value="RpoN_core-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32248">
        <property type="entry name" value="PTHR32248"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00309">
        <property type="entry name" value="Sigma54_AID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04963">
        <property type="entry name" value="Sigma54_CBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04552">
        <property type="entry name" value="Sigma54_DBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000774">
        <property type="entry name" value="RpoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00045">
        <property type="entry name" value="SIGMA54FCT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02395">
        <property type="entry name" value="rpoN_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00717">
        <property type="entry name" value="SIGMA54_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00718">
        <property type="entry name" value="SIGMA54_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 10" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5 10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="9 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sigma54_CBD" evidence="13">
        <location>
            <begin position="104"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma54_DBD" evidence="12">
        <location>
            <begin position="310"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="36"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN56550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="470" mass="50778" checksum="4A1CF48B0E88B835" modified="2016-02-17" version="1">MVMTPQLRQAIRLLQLSAVELEAELASAVESNPLLDWTEPAAPEPGEPVHASTVTSSSSTEDSAGGEGPGPESTSEPEWTMDDGETWYERVGPSDHDDDSSAAEQVADAETLLDHLLWQLHLSPLSPRDRSIGVAIIEAIDDDGYLREPLQAIADSLAPELSVGEDEVMTVLHQVQRFDPVGTGARSLAECLGLQLGTLSDDTPGKTLAQQIASGPLERLPRVGVAGLAAELKLDPAQVETAVQLLRSLDPRPGAQMGAISTDTYVTPDVVIWRQHGLWRVALSEAMRPRISIHRGYEGMIRHASAADASYLRGHLQEARWLLKSLEARGDTLLKVARCLLKQQAAFLEFGDSALRPLTLREVANEIGLHESTVSRAIARKYARTPRGTVPLRAFFASGIDTGAGGEASSTAIQAMIRRLIEAENPRKPLSDARLAETLKATGVPVARRTVAKYREAMSIPSSQDRVRMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDC5</accession>
    <name>A0A0S2DDC5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1125</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1125"/>
    <dbReference type="EnsemblBacteria" id="ALN56483">
        <property type="protein sequence ID" value="ALN56483"/>
        <property type="gene ID" value="GLE_1125"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1125"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1111"/>
    <dbReference type="OMA" id="VINPISW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021440">
        <property type="entry name" value="DUF3089"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11288">
        <property type="entry name" value="DUF3089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="367" mass="40708" checksum="6814006E57564C60" modified="2016-02-17" version="1">MVLDPKREFDRTPEPAAPDYRDARFWAALPEKRDDADATPIGMRNRQADAPVDVFFIHPTTYFSRAGWNQPLDDEQANRGTEFALRAQASAFNEVGRVYAPQYRQMTLNGYLSASDADRDRALDLAYRDVRAAFDAFLSQWSHGRPFIIAAHSQGSGHGLRLVSELMSDLSADPALRKRLVAAYLVGAAVPEDALRRTIPGVPLCATPEQTGCAVFFNAIEADAFEPGERPKRFEQVRAWYPGGFRSVEHPRLLCVNPVTWRADGESSPQSAHLGAIHAERNRPLPEPQPRRVSARCDGDGLLQTTLPDGEWRQWWFGGDQHVNDYQLFYMDIRANAARRAAAMRGATAPAAAKAAAKAAAGRKRGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDE7</accession>
    <name>A0A0S2DDE7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1138</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56496">
        <property type="protein sequence ID" value="ALN56496"/>
        <property type="gene ID" value="GLE_1138"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1138"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1123"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="50" mass="5697" checksum="A964BE6CD9EA70DB" modified="2016-02-17" version="1">MQERREPLPRQYGYDASCGVVTLSRLAPLLQVDREEKRGREGPVSVARRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDS2</accession>
    <name>A0A0S2DDS2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dipeptidyl-peptidase</fullName>
            <ecNumber evidence="2">3.4.14.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1324</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase S46 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.14.-" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1324"/>
    <dbReference type="EnsemblBacteria" id="ALN56681">
        <property type="protein sequence ID" value="ALN56681"/>
        <property type="gene ID" value="GLE_1324"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1324"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1308"/>
    <dbReference type="OMA" id="PGRTNRW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070009">
        <property type="term" value="F:serine-type aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019500">
        <property type="entry name" value="Pep_S46"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38469">
        <property type="entry name" value="PTHR38469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10459">
        <property type="entry name" value="Peptidase_S46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0720">Serine protease</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU366067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="700" mass="77005" checksum="A07067B125929639" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDV3</accession>
    <name>A0A0S2DDV3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dipeptidyl-peptidase</fullName>
            <ecNumber evidence="2">3.4.14.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_07090</name>
        <name evidence="3" type="ORF">GLE_1325</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase S46 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.14.-" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946690.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1325"/>
    <dbReference type="EnsemblBacteria" id="ALN56682">
        <property type="protein sequence ID" value="ALN56682"/>
        <property type="gene ID" value="GLE_1325"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1325"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1309"/>
    <dbReference type="OMA" id="KDWFFNP"/>
    <dbReference type="OrthoDB" id="99817at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070009">
        <property type="term" value="F:serine-type aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019500">
        <property type="entry name" value="Pep_S46"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38469">
        <property type="entry name" value="PTHR38469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10459">
        <property type="entry name" value="Peptidase_S46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0720">Serine protease</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU366067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="734" mass="80174" checksum="3FFC733D00DB6C94" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE04</accession>
    <name>A0A0S2DE04_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein-L-isoaspartate O-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.77</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">L-isoaspartyl protein carboxyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Protein L-isoaspartyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Protein-beta-aspartate methyltransferase</fullName>
            <shortName evidence="2">PIMT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 3" type="primary">pcm</name>
        <name evidence="4" type="ORF">BV903_21710</name>
        <name evidence="6" type="ORF">D9T17_19870</name>
        <name evidence="5" type="ORF">FE772_07855</name>
        <name evidence="3" type="ORF">GLE_1497</name>
    </gene>
    <organism evidence="3 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">C3</strain>
        </source>
    </reference>
    <reference evidence="4 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">OH11</strain>
        </source>
    </reference>
    <reference evidence="5 10" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 10">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[protein]-L-isoaspartate + S-adenosyl-L-methionine = [protein]-L-isoaspartate alpha-methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:12705"/>
            <dbReference type="Rhea" id="RHEA-COMP:12143"/>
            <dbReference type="Rhea" id="RHEA-COMP:12144"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90596"/>
            <dbReference type="ChEBI" id="CHEBI:90598"/>
            <dbReference type="EC" id="2.1.1.77"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.77" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000072">
        <property type="protein sequence ID" value="OPD61795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000048">
        <property type="protein sequence ID" value="ROU05097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946824.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000048.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1497"/>
    <dbReference type="EnsemblBacteria" id="ALN56854">
        <property type="protein sequence ID" value="ALN56854"/>
        <property type="gene ID" value="GLE_1497"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61795">
        <property type="protein sequence ID" value="OPD61795"/>
        <property type="gene ID" value="BV903_21710"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1497"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1478"/>
    <dbReference type="OMA" id="TISAIHM"/>
    <dbReference type="OrthoDB" id="1948290at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004719">
        <property type="term" value="F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00090">
        <property type="entry name" value="PIMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000682">
        <property type="entry name" value="PCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579">
        <property type="entry name" value="PTHR11579"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00080">
        <property type="entry name" value="pimt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01279">
        <property type="entry name" value="PCMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD61795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROU05097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="226" mass="24463" checksum="744A5DB391F91EBF" modified="2016-02-17" version="1">MIQRMRLQPEAIGSGLTSQRVRDRLVERLREAGIRDERVLNAIRTVPRHLFVDEALAMRAYEDTALPIGHNQTISQPWVVARMTEALFEDGPPAKVLEIGTGSGYQAAILAALGLEVHTVERIGELLRTARKRFRQLGLNVRSKHDDGRIGWPENGPFDAIIVTAAAPALVDALTEQLAPGGTLVAPVGAASSQSLLKLRKDADGNVAQTTLAPVVFVPLLSGMID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE35</accession>
    <name>A0A0S2DE35_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Methylated-DNA--protein-cysteine methyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.63</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">6-O-methylguanine-DNA methyltransferase</fullName>
            <shortName evidence="7">MGMT</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">O-6-methylguanine-DNA-alkyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ada</name>
        <name evidence="11" type="ORF">FE772_07230</name>
        <name evidence="10" type="ORF">GLE_1361</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>a 4-O-methyl-thymidine in DNA + L-cysteinyl-[protein] = a thymidine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:53428"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:13555"/>
            <dbReference type="Rhea" id="RHEA-COMP:13556"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:137386"/>
            <dbReference type="ChEBI" id="CHEBI:137387"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 7">
            <text>a 6-O-methyl-2'-deoxyguanosine in DNA + L-cysteinyl-[protein] = a 2'-deoxyguanosine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:24000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:11367"/>
            <dbReference type="Rhea" id="RHEA-COMP:11368"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:85445"/>
            <dbReference type="ChEBI" id="CHEBI:85448"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MGMT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.63" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946717.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1361"/>
    <dbReference type="EnsemblBacteria" id="ALN56718">
        <property type="protein sequence ID" value="ALN56718"/>
        <property type="gene ID" value="GLE_1361"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1361"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1343"/>
    <dbReference type="OMA" id="QANRANE"/>
    <dbReference type="OrthoDB" id="1327994at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003908">
        <property type="term" value="F:methylated-DNA-[protein]-cysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA dealkylation involved in DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00772">
        <property type="entry name" value="OGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001497">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008332">
        <property type="entry name" value="MethylG_MeTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023546">
        <property type="entry name" value="MGMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036631">
        <property type="entry name" value="MGMT_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02870">
        <property type="entry name" value="Methyltransf_1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="SSF46767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53155">
        <property type="entry name" value="SSF53155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00589">
        <property type="entry name" value="ogt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00374">
        <property type="entry name" value="MGMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 7 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_1N" evidence="9">
        <location>
            <begin position="12"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_binding_1" evidence="8">
        <location>
            <begin position="87"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; methyl group acceptor" evidence="7">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN56718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW25488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="180" mass="19576" checksum="889BF6D232407D94" modified="2016-02-17" version="1">MSSPIRLKRGEVRYQHIGSPVGRLLLASGEDGLRLIEFEEPWHPAAMDESWEEGDDAVLAATRRQLAEYFAGARRDFDLPLAPHGTAFQLQCWRTLALIPYGETWSYGQMARHLGQPTATRAVGAANGRNPLPIVLPCHRVIGADGSLTGFGGGLPVKKHLLTLEGALQEAPQVQDLFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEB3</accession>
    <name>A0A0S2DEB3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA pseudouridine synthase D</fullName>
            <ecNumber evidence="4">5.4.99.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridine(13) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridylate synthase D</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-uridine isomerase D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rluD</name>
        <name evidence="4" type="synonym">truD</name>
        <name evidence="6" type="ORF">GLE_1492</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>uridine(13) in tRNA = pseudouridine(13) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:42540"/>
            <dbReference type="Rhea" id="RHEA-COMP:10105"/>
            <dbReference type="Rhea" id="RHEA-COMP:10106"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.27"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the pseudouridine synthase TruD family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.27" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946819.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1492"/>
    <dbReference type="EnsemblBacteria" id="ALN56849">
        <property type="protein sequence ID" value="ALN56849"/>
        <property type="gene ID" value="GLE_1492"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1492"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1473"/>
    <dbReference type="OMA" id="LWLWVEK"/>
    <dbReference type="OrthoDB" id="1490777at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01082">
        <property type="entry name" value="TruD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001656">
        <property type="entry name" value="PsdUridine_synth_TruD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020119">
        <property type="entry name" value="PsdUridine_synth_TruD_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011760">
        <property type="entry name" value="PsdUridine_synth_TruD_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042214">
        <property type="entry name" value="TruD_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043165">
        <property type="entry name" value="TruD_insert_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01142">
        <property type="entry name" value="TruD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50984">
        <property type="entry name" value="TRUD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01268">
        <property type="entry name" value="UPF0024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TRUD" evidence="5">
        <location>
            <begin position="159"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN56849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="352" mass="38152" checksum="557887A1E530288E" modified="2016-02-17" version="1">MSGDDGLGGLPRAHGAPALRARIRSAPEDFRVEELPSFAASGSGEHLLLTVEKRGMNTAFAAKRLAQWAGVGEVAIGYAGLKDRHAVTVQRFSVHLPKRVAPALAELESDELRVLEHHWHAKKLPRGALAGNRFVLALRDVDGERDAVERRLRAIVADGVPNYFGEQRFGRDGDNVANALAMFAGRRVRREQRSLLLSAARSELFNRALAARVRDGSWAGLRDGTGLDGEVWSLAGSRSVFGPEPWSEALAERLARSDIHPSGPLWGRGELRSADAVRALELAALQDEQALALRAGLEAAGLEQERRALRLRAESLQWRWLDDGALELGFVLPAGAYATVVLAELGAIDGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DED7</accession>
    <name>A0A0S2DED7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flavodoxin-like fold family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">NAD(P)H-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_07955</name>
        <name evidence="2" type="ORF">GLE_1517</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946842.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1517"/>
    <dbReference type="EnsemblBacteria" id="ALN56874">
        <property type="protein sequence ID" value="ALN56874"/>
        <property type="gene ID" value="GLE_1517"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1517"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1499"/>
    <dbReference type="OMA" id="LFPIHHG"/>
    <dbReference type="OrthoDB" id="1143659at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003680">
        <property type="entry name" value="Flavodoxin_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02525">
        <property type="entry name" value="Flavodoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin_2" evidence="1">
        <location>
            <begin position="3"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="264" mass="29025" checksum="34BF4EF3F170D918" modified="2016-02-17" version="1">MNKHILIVHAHPEPASLNGALKDAMHAHLLAQGHSVEVSDLYAMGWKAAVDAADFPQRDASARLRVPKDSHAAFAADALTADVRAEQDKLRRADALILQFPLWWYSMPAILKGWFDRVYSYGFGYGVGEHSERHWGDRYGEGALAGKRALVSVTAGGWQPHYSPRGINGPIDDLLFPINHGLLHYPGFDVLPPYVVYRSDRVDAGQFAQARDGLLRRLDGLWSDAPIAYRRQNSGDYAVPSLELKPGREAGGERGFGLHVAPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEG5</accession>
    <name>A0A0S2DEG5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Formiminoglutamate deiminase</fullName>
            <ecNumber evidence="2">3.5.3.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">hutF</name>
        <name evidence="2" type="ORF">GLE_1360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.3.13" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1360"/>
    <dbReference type="EnsemblBacteria" id="ALN56717">
        <property type="protein sequence ID" value="ALN56717"/>
        <property type="gene ID" value="GLE_1360"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1360"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1342"/>
    <dbReference type="OMA" id="MCPTTER"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050416">
        <property type="term" value="F:formimidoylglutamate deiminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010252">
        <property type="entry name" value="HutF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43608">
        <property type="entry name" value="PTHR43608"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02022">
        <property type="entry name" value="hutF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="16"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="429" mass="47168" checksum="329AC744A38F7C76" modified="2016-02-17" version="1">MWTPQGWRGDASAERIVPGIANLHSHAFQRAMAGMAERQTNPSLGLGPSGGHDSFWTWRETMYRFAARFTPDALHAVAAQLYAEMLEAGYTSVCEFHYLHHAPDGRPYADPAAMSRALIEAARDTGIRMTLLPVLYMTGGFDERPLGERQRRFGHRVDAYLRLLDTLRAEQNATLRVGCCLHSLRAVPPAPMREVLAALPADSRVHMHIAEQVAEVEDCVAVRGARPVRWLLDNAQVDERWTLVHATHLDEGEVRDTARSGATVAICTTTEANLGDGLFPLRDYLDAGGYWGVGSDSHISVSPVEELRWLEYGQRLVTRRRNIAVSVGADGSDSVGETLLRGVAASAQRSTGFDAAALAGDTLVLDRDAPAFAGATDADYVDRWLFSGNRNLVREAFVGGERVVVEGRHRDREAIARRYGETLRALLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEM6</accession>
    <name>A0A0S2DEM6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosomal RNA large subunit methyltransferase K/L</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="5">23S rRNA m2G2445 methyltransferase</fullName>
                <ecNumber evidence="5">2.1.1.173</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="5">rRNA (guanine-N(2)-)-methyltransferase RlmL</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="5">23S rRNA m7G2069 methyltransferase</fullName>
                <ecNumber evidence="5">2.1.1.264</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="5">rRNA (guanine-N(7)-)-methyltransferase RlmK</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="5" type="primary">rlmL</name>
        <name evidence="9" type="ORF">GLE_1605</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>guanosine(2069) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(2)-methylguanosine(2069) in 23S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43772"/>
            <dbReference type="Rhea" id="RHEA-COMP:10688"/>
            <dbReference type="Rhea" id="RHEA-COMP:10689"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74481"/>
            <dbReference type="EC" id="2.1.1.264"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>guanosine(2445) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(2)-methylguanosine(2445) in 23S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42740"/>
            <dbReference type="Rhea" id="RHEA-COMP:10215"/>
            <dbReference type="Rhea" id="RHEA-COMP:10216"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74481"/>
            <dbReference type="EC" id="2.1.1.173"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the methyltransferase superfamily. RlmKL family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.173" evidence="5"/>
    <dbReference type="EC" id="2.1.1.264" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946916.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1605"/>
    <dbReference type="EnsemblBacteria" id="ALN56962">
        <property type="protein sequence ID" value="ALN56962"/>
        <property type="gene ID" value="GLE_1605"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1605"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1586"/>
    <dbReference type="OMA" id="WIRGYEA"/>
    <dbReference type="OrthoDB" id="307177at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052915">
        <property type="term" value="F:23S rRNA (guanine(2445)-N(2))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070043">
        <property type="term" value="F:rRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01858">
        <property type="entry name" value="23SrRNA_methyltr_KL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017244">
        <property type="entry name" value="23SrRNA_methyltr_KL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000241">
        <property type="entry name" value="RNA_methylase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019614">
        <property type="entry name" value="SAM-dep_methyl-trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004114">
        <property type="entry name" value="THUMP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10672">
        <property type="entry name" value="Methyltrans_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02926">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01170">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037618">
        <property type="entry name" value="RNA_Mtase_bacteria_prd"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00981">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51165">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01261">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 5 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="THUMP" evidence="8">
        <location>
            <begin position="43"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="323"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="329"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="788" mass="85727" checksum="70BA68272FCF9E81" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEN6</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">BV903_07205</name>
        <name evidence="5" type="ORF">D9T17_18885</name>
        <name evidence="4" type="ORF">FE772_08695</name>
        <name evidence="2" type="ORF">GLE_1677</name>
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    <organism evidence="2 6">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">C3</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 9" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000013">
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    </dbReference>
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        <property type="protein sequence ID" value="QCW25733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000045">
        <property type="protein sequence ID" value="ROU05476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57033">
        <property type="protein sequence ID" value="ALN57033"/>
        <property type="gene ID" value="GLE_1677"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64668">
        <property type="protein sequence ID" value="OPD64668"/>
        <property type="gene ID" value="BV903_07205"/>
    </dbReference>
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU05476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="77" mass="8269" checksum="89F33808CA152E75" modified="2016-02-17" version="1">MGFHIGITAALVAAGLLGLDLYATWAVWREPDLTGAQKGLQSAMVWLLPLLGAIVVLNVVRSMNREPTARSTFTTSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEN9</accession>
    <name>A0A0S2DEN9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56797">
        <property type="protein sequence ID" value="ALN56797"/>
        <property type="gene ID" value="GLE_1440"/>
    </dbReference>
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    <dbReference type="PATRIC" id="fig|69.6.peg.1420"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="51" mass="5448" checksum="494F4B3E971E6968" modified="2016-02-17" version="1">MPWVRDGERTAPGAGFADRGWRGIAGGAAVERRWSRLCAAPARAAKAAWPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DES0</accession>
    <name>A0A0S2DES0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
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        <name evidence="1" type="ORF">GLE_1638</name>
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        <name type="scientific">Lysobacter enzymogenes</name>
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            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56995">
        <property type="protein sequence ID" value="ALN56995"/>
        <property type="gene ID" value="GLE_1638"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="39" mass="3983" checksum="2FD36CBC885309C8" modified="2016-02-17" version="1">MQAAVPWKSGADGSADQINGAIVGTGLLTIRKARVRASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEU9</accession>
    <name>A0A0S2DEU9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Succinate-semialdehyde dehydrogenase</fullName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">gabD</name>
        <name evidence="5" type="ORF">GLE_1742</name>
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    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the aldehyde dehydrogenase family.</text>
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        <property type="protein sequence ID" value="ALN57097.1"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_1742"/>
    <dbReference type="EnsemblBacteria" id="ALN57097">
        <property type="protein sequence ID" value="ALN57097"/>
        <property type="gene ID" value="GLE_1742"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1742"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009013">
        <property type="term" value="F:succinate-semialdehyde dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Ald_DH_N"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="484"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="495" mass="53590" checksum="D8E81737975ABD90" modified="2016-02-17" version="1">MAKSEKKSKAAKPAKGLKSSYPYYLAGRAVAANGDLDVLDKYSGKRATRVAMADAAAVRKAIVAAHKAREAMAQFAPDRRRDVLEHCVRRFGERFEELALALCIEAGKPIKDARGEVTRLIDTFRIAAGEATRDPGTLLELQISPRTRGYRGMVKRVPIGPCSFITPFNFPLNLVAHKVAPAIAAGCPFVLKPAIKTPVGALIIAEILAETDLPEGAFSVLCCSNEDASLLVEDERIKLLSFTGGLIGWDLKARAGKKKVTLELGGNAACIVDADPGASLDHVVERLVFGAYYQSGQSCISVQRIYAHADVYDKLRKKLKAAVGALRMGDPREESTFIGPVVDEQAAQRIQAWIDAALKGGAKRIAGGARQGTMIPATLLENVPRDAELYRKEAFGPVALIEPFDDFDAVIDRVNDSDFGLQAGVFTGRLDHAMRAWDRLDVGGVIVGDVPSFRVDNMPYGGVKDSGQGREGVRYAIEDMSEQRLLVIRDPTEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEW3</accession>
    <name>A0A0S2DEW3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chromosome segregation protein SEQUENCING GAP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_07250</name>
        <name evidence="4" type="ORF">FE772_08740</name>
        <name evidence="2" type="ORF">GLE_1686</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57042.1"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Fernandez C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 6">B25</strain>
        </source>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 7">YC36</strain>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    </dbReference>
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        <property type="entry name" value="RNA_pol_sigma-70-like"/>
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        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
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        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
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        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07638">
        <property type="entry name" value="Sigma70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02999">
        <property type="entry name" value="Sig-70_X6"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="187" mass="20747" checksum="F6B9E7F3AD359F7C" modified="2016-02-17" version="1">MDLQPEETGDVTRLLAAWRAGDAAAPDALLNLVYRQLRNIAAGRLSRLSVPVLDPTELVNEAMLRLLGGNGLDAQNRQHFFSIAATAIRYVLVDTIRRQHADKRGGGVVDVTLSGSEHLSAAGDRWLDVEDALRALEQQDPRKCRIVELIFLMGLNQQETAEILGVSLTTVERDLRFAKAWLREHLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFK8</accession>
    <name>A0A0S2DFK8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_09970</name>
        <name evidence="2" type="ORF">GLE_1962</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57313">
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        <property type="gene ID" value="GLE_1962"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1962"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1927"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="36"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="63" mass="6878" checksum="0860B7BD0B689F94" modified="2016-02-17" version="1">MAASSDAIRAHRTAFIDLKYFLITVVRARVRARAANVRTHAPQGRARGVETESAQAFAAAPKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFX1</accession>
    <name>A0A0S2DFX1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phage Tail Collar</fullName>
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        <submittedName>
            <fullName evidence="4">Phage tail protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_10540</name>
        <name evidence="3" type="ORF">GLE_2083</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW26040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947264.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2083"/>
    <dbReference type="EnsemblBacteria" id="ALN57433">
        <property type="protein sequence ID" value="ALN57433"/>
        <property type="gene ID" value="GLE_2083"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2083"/>
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    <dbReference type="OMA" id="QPYLAMN"/>
    <dbReference type="OrthoDB" id="1837650at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="8"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="176" mass="18504" checksum="03AB4A706B49E6DA" modified="2016-02-17" version="1">MTEPFIAQIQQFGFNFAPRGWAACNGATMAIQQNTALFALLGTQYGGNGQTTFQLPNFINRAATNQGRGPGLTPHDIGEPFGVNAVTLTTNEMPTHSHSLNIYNQPTDTKKAPSPSNGNSLGSPSMNAFVASNAANAPLAPTVLQPAGGGQPHENRQPYLAMNFCIALQGVFPAFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFY5</accession>
    <name>A0A0S2DFY5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2116</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57466">
        <property type="protein sequence ID" value="ALN57466"/>
        <property type="gene ID" value="GLE_2116"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2116"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2080"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="39" mass="4640" checksum="94D66CCD46F37295" modified="2016-02-17" version="1">MREGFRARRLPLRRGAVASSIKKSRQADKRQEQFPNIWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG55</accession>
    <name>A0A0S2DG55_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tryptophan synthase alpha chain</fullName>
            <ecNumber evidence="7">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">trpA</name>
        <name evidence="9" type="ORF">GLE_2148</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the TrpA family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947317.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2148"/>
    <dbReference type="EnsemblBacteria" id="ALN57498">
        <property type="protein sequence ID" value="ALN57498"/>
        <property type="gene ID" value="GLE_2148"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2148"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2112"/>
    <dbReference type="OMA" id="LVMTYWN"/>
    <dbReference type="OrthoDB" id="912786at2"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04724">
        <property type="entry name" value="Tryptophan_synthase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00131">
        <property type="entry name" value="Trp_synth_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018204">
        <property type="entry name" value="Trp_synthase_alpha_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002028">
        <property type="entry name" value="Trp_synthase_suA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43406">
        <property type="entry name" value="PTHR43406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00290">
        <property type="entry name" value="Trp_syntA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00262">
        <property type="entry name" value="trpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00167">
        <property type="entry name" value="TRP_SYNTHASE_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6 7 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN57498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="267" mass="27427" checksum="D5A94A2DFAE01AD4" modified="2016-02-17" version="1">MNRIDAKFQQLQAAGRKALIPFLTAGDPSLEATVPAMHALVAAGADVVELGVPFSDPMADGPTIQRSSERAIARGAGLGWVLQAVAEFRQGDADTPVVLMGYLNPIEIRGAQRFAHDAVAAGVDGVLLVDLPPEEAAELRAAFAHAGLALILLASPTTTDERLALLCDGAQGYLYYVSFAGVTGADRLDAGAANDRLHRIRQQSRVPVVAGFGIKDAASAAAMAREAEGVVVGSALVAVLAEAASAQAAAQAARDFLAPLRAALDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGB2</accession>
    <name>A0A0S2DGB2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2279</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57628">
        <property type="protein sequence ID" value="ALN57628"/>
        <property type="gene ID" value="GLE_2279"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2279"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2244"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="54" mass="6045" checksum="206BBBB514162976" modified="2016-02-17" version="1">MPRSGRARCDPRAVGAGLPALAPWPLTLHGSRQDGSRRRRQHSNNRRRRHAHGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGN5</accession>
    <name>A0A0S2DGN5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CheW domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947546.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2450"/>
    <dbReference type="EnsemblBacteria" id="ALN57799">
        <property type="protein sequence ID" value="ALN57799"/>
        <property type="gene ID" value="GLE_2450"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2450"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2413"/>
    <dbReference type="OMA" id="IDDCWNR"/>
    <dbReference type="OrthoDB" id="1711729at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039315">
        <property type="entry name" value="CheW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22617">
        <property type="entry name" value="PTHR22617"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheW-like" evidence="1">
        <location>
            <begin position="53"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="199" mass="20992" checksum="56EF493B818EE20C" modified="2016-02-17" version="1">MSASDLGDAATGGERGHARSAVARLLERVPAREDLAAAAARLAAGAVEQRGDAASAFVFRLGEEWLGLTTALVDEVLELRPVHRLPHRHDAALRGLVNVRGRLTVCVALPALLQTGPAPAVRGGARRLVVLAAPEGALAFEADEVHGSLRYPLDDVRAVPSTVAHAVARFATGVLPWGERRVGLLDADLLLHALDRRIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGU4</accession>
    <name>A0A0S2DGU4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Di-heme cytochrome c peroxidase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_2404</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2404"/>
    <dbReference type="EnsemblBacteria" id="ALN57753">
        <property type="protein sequence ID" value="ALN57753"/>
        <property type="gene ID" value="GLE_2404"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2404"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2366"/>
    <dbReference type="OMA" id="YKFANVG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004852">
        <property type="entry name" value="Di-haem_cyt_c_peroxidsae"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03150">
        <property type="entry name" value="CCP_MauG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595550" evidence="2">
        <location>
            <begin position="27"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="CCP_MauG" evidence="3">
        <location>
            <begin position="117"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="405" mass="44519" checksum="BB98D73DE48A5A45" modified="2016-02-17" version="1">MRGDKRWLANLAVAAASALLFAAAFAGLLWAGASAAQTAQMAPGADSADSADNADLDACRRRLDAGGAQIDRDCLRRVYALPIEQWPRPLTDPGARWSELAPLPRQAPHPPGHPPDPAKVALGKRLFEDPRLSGSGQIACANCHDSELGWGDGRSVPFGHDRQRGRRNAPSVAMSGFAAHLFWDGRASTLEEQVLHPLTDPREMAARPAAVLRALRRDESYRRQYAQAFGSPGIDLARTAQALAGFQRSLVPRFNRFDRFLEGNRGALDDRELWGLHLFRTRARCMNCHSGATLSDDGFHNLGLHFYGRKLQDLGRYEVTGDPADSGKFKTPSLRNVAKTGPWMHNGRFATLRGVVNLYNAGMPRPQPSPQQIGDPLFPQPDPLLHRLDLHRTELEAITAFLETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGV8</accession>
    <name>A0A0S2DGV8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_02455</name>
        <name evidence="3" type="ORF">FE772_12180</name>
        <name evidence="1" type="ORF">GLE_2437</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000004">
        <property type="protein sequence ID" value="OPD65637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947538.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57786">
        <property type="protein sequence ID" value="ALN57786"/>
        <property type="gene ID" value="GLE_2437"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65637">
        <property type="protein sequence ID" value="OPD65637"/>
        <property type="gene ID" value="BV903_02455"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2437"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2399"/>
    <dbReference type="OrthoDB" id="2004462at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046197">
        <property type="entry name" value="DUF6229"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19740">
        <property type="entry name" value="DUF6229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD65637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="61" mass="6441" checksum="B0278C83F2A4CD3E" modified="2016-02-17" version="1">MQSNDLVSGWLTGAETVMGFDNPAGPLYLEGENAVEDAARAPITHSTSISTCPTGRCYCCM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH52</accession>
    <name>A0A0S2DH52_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type VI secretion system baseplate subunit TssE</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Type VI secretion system lysozyme-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tssE</name>
        <name evidence="3" type="ORF">FE772_12925</name>
        <name evidence="2" type="ORF">GLE_2576</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947649.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2576"/>
    <dbReference type="EnsemblBacteria" id="ALN57925">
        <property type="protein sequence ID" value="ALN57925"/>
        <property type="gene ID" value="GLE_2576"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2576"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2535"/>
    <dbReference type="OMA" id="DPYPLEF"/>
    <dbReference type="OrthoDB" id="1918415at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007048">
        <property type="entry name" value="IraD/Gp25-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017737">
        <property type="entry name" value="TssE1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04965">
        <property type="entry name" value="GPW_gp25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03357">
        <property type="entry name" value="VI_zyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GPW_gp25" evidence="1">
        <location>
            <begin position="39"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="167" mass="18695" checksum="CEEDC3CCA68E2ADE" modified="2016-02-17" version="1">MAELSQQERLQPSLLDRLIDENRHEIVESRDARAITAAKLRQCIVRDLSWLLNCTRHWSDEALEAHPYVAASVLNYGIPDLAGTLLEGLDVSALQSRIQAAILAFEPRLLASGLQVTARVDPQRSDHLALSFVIESEMWAQPIPLSLSLRTEVDLETGRFSLVEGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH90</accession>
    <name>A0A0S2DH90_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FE772_12875</name>
        <name evidence="9" type="ORF">GLE_2565</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947641.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2565"/>
    <dbReference type="EnsemblBacteria" id="ALN57914">
        <property type="protein sequence ID" value="ALN57914"/>
        <property type="gene ID" value="GLE_2565"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2565"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2524"/>
    <dbReference type="OMA" id="AWISESI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="187"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="248"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN57914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW26426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="454" mass="49459" checksum="3B14BDF6EF672E8F" modified="2016-02-17" version="1">MRNPIPFFFRVPSLSRRIAWRVGLGVVSLIFVLFAILCVVLWKPEARTIYRDTADDAAQAIDRRGATLVLDPARLPQRLREAPETAWLAAVDDAGHTLTWGKLPPEYRPVVAMLPLLSDSDLRSPDPRLAATLVVAERDWGRLRIIVGGVPEEGVIGLFAPLFYFVGLWMALPVAIVILLLVPWIVRRGLRGIGEVAEQARGVDMNRRSRHLDAAAVPSELKPLIDAFNQALDRIWDAAESRDRFLGNAAHELRLPIAIVRARASALSAGHAKTSLLSDIVRLENISEQLLDLQRIDRGLVANDTLDLVQVCREVGEDIAPLLVKAGYAFSFDAPAQPVYVSGDVGALQRVVMNLLQNAMTHGGGAGGIELSVSADARISVSDAGPGIAEEEYPQIFSPFYRLNPSAQGSGLGLHLAREVVTRHRGSIRVSRSSQGGARFCVQLPLLRPPARGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHJ2</accession>
    <name>A0A0S2DHJ2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type VI secretion-associated protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Type VI secretion-associated protein, BMA_A0400 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_00130</name>
        <name evidence="1" type="ORF">GLE_2587</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000001">
        <property type="protein sequence ID" value="OPD65958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947658.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000001.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2587"/>
    <dbReference type="EnsemblBacteria" id="ALN57936">
        <property type="protein sequence ID" value="ALN57936"/>
        <property type="gene ID" value="GLE_2587"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65958">
        <property type="protein sequence ID" value="OPD65958"/>
        <property type="gene ID" value="BV903_00130"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2587"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2546"/>
    <dbReference type="OMA" id="PWHVAMQ"/>
    <dbReference type="OrthoDB" id="650709at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017748">
        <property type="entry name" value="TagF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038225">
        <property type="entry name" value="TagF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09867">
        <property type="entry name" value="TagF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03373">
        <property type="entry name" value="VI_minor_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD65958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="205" mass="22106" checksum="30110A84E2E8A58E" modified="2016-02-17" version="1">MSGLHATVGFYGKLPCVGDFVRRRLPDAFVAPWDAAMQRLLLSASGDDAPARDDASRWRFALAPGVCGDRAWIGCVGASRDRVGRAFPLVLAAPLAAAVPAWFDAAERLYAQALRGEFADVEAFDRACARLRADAADDPRLAAWRRAHAGDDGRRCSLWWRADAPARRGAWITGVGLAFAEGGRELDLAYAPLPAQRTDLVEADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHK1</accession>
    <name>A0A0S2DHK1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AP endonuclease, family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2608</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2608"/>
    <dbReference type="EnsemblBacteria" id="ALN57956">
        <property type="protein sequence ID" value="ALN57956"/>
        <property type="gene ID" value="GLE_2608"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2608"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2568"/>
    <dbReference type="OMA" id="LWHVKDM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="2">
        <location>
            <begin position="38"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="274" mass="29344" checksum="CBE1C1EE70C3B1ED" modified="2016-02-17" version="1">MLLTALPAFAQRADTRAKPIAVQMYTLREVVSLDEQLKIVHDAGIRAVETVGTQDVSSKRLKRLLAKYSIKAISTHAQLTNLRRDLDGVVAFNKAVGTTTLVVPYLAKEERPTDAAGWIALGKELGGIADKLRAKGMTLAYHNHDFELAEPAGSGGKTGLELLFEGAGPSLQAELDLAWIARAGHDPVALLGKFRGRVFAVHAKDNAPQGQAKDEDGFAALGQGVLDWNAILPAAERAGVRWYILEHDHPLDPAAVVKTGAAYLNQHLPAGAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHQ4</accession>
    <name>A0A0S2DHQ4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2807</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58155">
        <property type="protein sequence ID" value="ALN58155"/>
        <property type="gene ID" value="GLE_2807"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2807"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2764"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595194" evidence="1">
        <location>
            <begin position="17"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="219" mass="22141" checksum="947062924468A86A" modified="2016-02-17" version="1">MKTANVLGLAMTVALAACSGQSAPEAAAKPAAEPAATSSAAAPASADAATATTAPAAAAPVGDARSLCAAGDDVVISCKVAGGAQLLSLCASKGVSDQSGTVYFAQGEAGKPDYVFPADKSAPAGRFKRTQLGFAGNTGGYAYSFEDGGRKRIFYSVSGERGLEEQGVLTVAGDADKAESALGCEPGSVVRNEDDALFKFTRSWDRDERIDQHGLPAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DID2</accession>
    <name>A0A0S2DID2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2651</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57999">
        <property type="protein sequence ID" value="ALN57999"/>
        <property type="gene ID" value="GLE_2651"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2651"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="50" mass="5985" checksum="EFEE1FA59C7D8F3B" modified="2016-02-17" version="1">MRCPRIKSRIELLAYKIYLRNNMIRVRAVDPGRRCSRRRSPGLSATRKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIG5</accession>
    <name>A0A0S2DIG5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Small-conductance mechanosensitive channel</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FE772_14385</name>
        <name evidence="8" type="ORF">GLE_2878</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homoheptamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2878"/>
    <dbReference type="EnsemblBacteria" id="ALN58226">
        <property type="protein sequence ID" value="ALN58226"/>
        <property type="gene ID" value="GLE_2878"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2878"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2840"/>
    <dbReference type="OMA" id="RIGFTVI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006686">
        <property type="entry name" value="MscS_channel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008910">
        <property type="entry name" value="TM_helix"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05552">
        <property type="entry name" value="TM_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01246">
        <property type="entry name" value="UPF0003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU369025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW26663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="335" mass="35217" checksum="7EE96D7E0BE9D45E" modified="2016-02-17" version="1">MAKSDAVVATTAQTVQAAPAKAAAAKAQAADPVIGLGAGFDFDKLMGWAQTQGLKLLAALAILLIGLWIAKRLSRALERVMTRANMEVTLRGFLRNIAYAVMVVVVAVAALQALGVPTTSVLAVLGAAGLAIGLALKDSLSNIASGVMLIVLRPFRAGDYVQAAGVEGTVEQIRVFQTRLRTIDNRVIVLPNSLITTAVIVNFTANPKRRIDLTVGVGYDDDLRVAKDTLLALAGAHPKVLKDPAPEVLVTALAESSVNLELRAWAKTGDLVHTKSDLVEAIRNDLIGKGLNIPYPQRDLHVYHHDADGRPIGEVLTKAVADDGDVAAAGAKPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DII0</accession>
    <name>A0A0S2DII0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2960</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2960"/>
    <dbReference type="EnsemblBacteria" id="ALN58308">
        <property type="protein sequence ID" value="ALN58308"/>
        <property type="gene ID" value="GLE_2960"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2960"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2921"/>
    <dbReference type="OMA" id="RRDDFHW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="27"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="313" mass="33548" checksum="63B69D59AFDABBA8" modified="2016-02-17" version="1">MNSHHNGESDSPTSQPSPARRALAALPPLGALRCFEAAARLGSFTRAAQELHLTHGAISRAVRSIEDALGVALFERRSQRVHLTAAGERLRDAAAAAFDLLAATVRELREPARKPALVLSCEPTLLMRWLIPRLPAFQAAHPQIALQWVAGGGPVGFGEVDLAIRRNDFSWGREVHAQHLFDERVGPVCSPAYRDARVDGAGRGARLSEGAVLLHSATRPDAWAQWARAARRRLPRAPAQTFEHFYFSLQAAAAGVGVAIGPWQLVRDDVDAGVLAAPFGFVADGSAYFLLSPAPARAGTPVALLAAWLRAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIL5</accession>
    <name>A0A0S2DIL5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-deoxy-manno-octulosonate cytidylyltransferase</fullName>
            <ecNumber evidence="2">2.7.7.38</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">CMP-2-keto-3-deoxyoctulosonic acid synthase</fullName>
            <shortName evidence="2">CKS</shortName>
            <shortName evidence="2">CMP-KDO synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 3" type="primary">kdsB</name>
        <name evidence="4" type="ORF">FE772_15155</name>
        <name evidence="3" type="ORF">GLE_3031</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>3-deoxy-alpha-D-manno-oct-2-ulosonate + CTP = CMP-3-deoxy-beta-D-manno-octulosonate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23448"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:85986"/>
            <dbReference type="ChEBI" id="CHEBI:85987"/>
            <dbReference type="EC" id="2.7.7.38"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; CMP-3-deoxy-D-manno-octulosonate biosynthesis; CMP-3-deoxy-D-manno-octulosonate from 3-deoxy-D-manno-octulosonate and CTP: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KdsB family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.38" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947992.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3031"/>
    <dbReference type="EnsemblBacteria" id="ALN58378">
        <property type="protein sequence ID" value="ALN58378"/>
        <property type="gene ID" value="GLE_3031"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3031"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2991"/>
    <dbReference type="OMA" id="FMATCAK"/>
    <dbReference type="OrthoDB" id="1345588at2"/>
    <dbReference type="UniPathway" id="UPA00358">
        <property type="reaction ID" value="UER00476"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008690">
        <property type="term" value="F:3-deoxy-manno-octulosonate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033468">
        <property type="term" value="P:CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02517">
        <property type="entry name" value="CMP-KDO-Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00057">
        <property type="entry name" value="KdsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003329">
        <property type="entry name" value="Cytidylyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004528">
        <property type="entry name" value="KdsB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02348">
        <property type="entry name" value="CTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00466">
        <property type="entry name" value="kdsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="2 3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="271" mass="28643" checksum="AAA62B919AA6A24A" modified="2016-02-17" version="1">MSQDFVVAIPARYAASRLPGKPLRELAGEPLVLHVARRALAAGAREVWIATDDARIADALKDCGVQVAMTSPDHASGTDRLAECADIAGWRDDTVVVNLQGDEPFAPAAGIVAVADALRDSGAEMSTLAVAVTEVETLFDPNAVKLVRAANGDALYFSRAPIPWPRDAFAKDRERMPGGGDWLRHIGIYGYRAGFLRKFAKMRPGRLEQIESLEQLRALEAGYRIAVGITPEAFPPGVDTPEDLARAEAFLAAQGAAGEGAADKGAAGQGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIN2</accession>
    <name>A0A0S2DIN2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3049</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58396">
        <property type="protein sequence ID" value="ALN58396"/>
        <property type="gene ID" value="GLE_3049"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3049"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3009"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595647" evidence="1">
        <location>
            <begin position="25"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="253" mass="25679" checksum="C17478435C7DF867" modified="2016-02-17" version="1">MIRACMIRVPLLVLSLLAPLGAGAYEPARTPIQAPVPAPAASAAVSVPSAAAAPAPATVAAPAPAPVASVPAAPASSAPAPVATAPTVVASKAVALPPMRFLASVAEEEIYTGLKSDPNFAALDKELVGSPLSLMVTHTLRPTAGGMAAGLLSAVLAGSTLGLIPMVSSERLVIKYDVMLNGRPLTGYTFERTATRAQNLWAVDAGGLGKAGMEWVKSTVPDAAAKIAKDPAVLALRQEMDFYFPPETVAARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIN8</accession>
    <name>A0A0S2DIN8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inorganic anion transporter, sulfate permease (SulP) family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">SulP family inorganic anion transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_15110</name>
        <name evidence="7" type="ORF">GLE_3023</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3023"/>
    <dbReference type="EnsemblBacteria" id="ALN58371">
        <property type="protein sequence ID" value="ALN58371"/>
        <property type="gene ID" value="GLE_3023"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3023"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2984"/>
    <dbReference type="OMA" id="GCWFRVT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="PTHR11814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="155"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="250"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="293"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="332"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="382"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfate_transp" evidence="6">
        <location>
            <begin position="17"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW26779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="509" mass="52675" checksum="AF0D1421E209AD1E" modified="2016-02-17" version="1">MLNAACVKNYFAQGLFGRDLLGSVVVFLVALPLCMGIAIASDMPPAAGLITGIVGGVVVGAIAGSPLQVSGPAAGLAVLVFELVREHGASALGPVILLAGAIQLLAGLCRAGVWFRMTSPAVVAGMLSGIGILIVASQLHVLIDAVPKARGLENFAAFPAALGAALSGSGGANATALLVGIATIAILLLWDTLRPARLRFLPGALLAVVALTALSQLLALDVKRVQMPSNLLAAISLPNAASLSRLAEPAMLAAALTFALIASAETLLSAAAVDRMHDGPRTGYDRELGAQGVGNLICGALGALPMTGVIVRSATNVQAGSATRMATIFHGLLILLFAALLPWLVRMTPVACLAGILVYIGAKMINLRQARSFAAFGKGWALIYFATVAAIVATDLLIGVLVGFALSLLRLALQASRLQVRLVHDADGRASLRLEGSATFLKVPAMARALERVPPNTRVRLDHDRLHHLDQACLELLRDWGRNASARGCELAVDWQALQRRVEGAPARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJD8</accession>
    <name>A0A0S2DJD8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MATE efflux family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3248</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58594">
        <property type="protein sequence ID" value="ALN58594"/>
        <property type="gene ID" value="GLE_3248"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3248"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3202"/>
    <dbReference type="OMA" id="VGNWIGS"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
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        <property type="match status" value="2"/>
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            <end position="76"/>
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            <end position="211"/>
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    <feature type="transmembrane region" description="Helical" evidence="2">
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            <end position="262"/>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
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        <source>
            <dbReference type="EMBL" id="ALN58594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="497" mass="52668" checksum="C3DB95F7B44240DA" modified="2016-02-17" version="1">MLTEGPIGRTMISFALPIMAGNAAQSLNGSINSIWVGRYLGEAALTATANANNIMFFLIGSMFGVGMAATILIGQATGARDTARARRIMGTSASFFLGLSVAIAAVGWFFADAILRGMGTPPAAQPLAEQYLRVIFLSIPFIYAFAFLSSALRGLGDSRTPFRFLLMSVALDIVLNPLLIFGWGPLPGLGIAGSALSTFIGQGASLAALLLHLRRKRHVLWLGRGDAHLLKIDPAVLRALIVKGVPMGLQMVLISLAMIAMIRLVNAHGTAIAAGYGAALQLWTYVQMPAMAIGAACSSIAAQSVGAGRWDRVDAAARTGTLFNFLLTGALIAPLILFDRYTLALFLPDGSASFEIARHLNHIAIFSFLFFGVTFVISGVVRATGAVIPPLLILGSALWGVRVPFATFLQPVLGLDALWWSFPVSALCSMLVSMAYYRWGGWRRAKMMAAPERVAAPLATQTIATPAEVPAHTPAPVADTSPNDDAVAVDEDRLERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJH7</accession>
    <name>A0A0S2DJH7_LYSEN</name>
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        <submittedName>
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        <submittedName>
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        <dbReference type="NCBI Taxonomy" id="69"/>
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            <taxon>Proteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10 12">YC36</strain>
        </source>
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    <comment type="similarity">
        <text evidence="1">Belongs to the asparagine synthetase family.</text>
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    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_3352"/>
    <dbReference type="EnsemblBacteria" id="ALN58698">
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        <property type="gene ID" value="GLE_3352"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3352"/>
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    <dbReference type="OMA" id="DWSGIYS"/>
    <dbReference type="OrthoDB" id="610569at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="project" value="UniProtKB-EC"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="2"/>
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        </location>
    </feature>
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            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="101"/>
        </location>
        <ligand>
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        </ligand>
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        </ligand>
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        <ligand>
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            <position position="353"/>
        </location>
    </feature>
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        <source>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
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        <source>
            <dbReference type="PIRSR" id="PIRSR001589-1"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN58698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="561" mass="62061" checksum="4BA0A987A6310108" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJR5</accession>
    <name>A0A0S2DJR5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_17975</name>
        <name evidence="4" type="ORF">FE772_16900</name>
        <name evidence="2" type="ORF">GLE_3427</name>
    </gene>
    <organism evidence="2 5">
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        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_MTAY01000048.1"/>
    </dbReference>
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    </dbReference>
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        <property type="gene ID" value="BV903_17975"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
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        <location>
            <begin position="26"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="76" mass="8043" checksum="7663C979EBA1D505" modified="2016-02-17" version="1">MNMMIKGIAIGLFAMGAVIGGSANAIPTATCDSAHVGAVRTEWVGDVAYKYECDGSGWQLVSKCGWVGTRWVCMNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJR6</accession>
    <name>A0A0S2DJR6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_3406</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="DUF6053"/>
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            <end position="948"/>
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            <end position="1442"/>
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            <end position="403"/>
        </location>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF13116"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF13502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1462" mass="150265" checksum="880F0762FEA00763" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJT0</accession>
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        <submittedName>
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        <submittedName>
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        </submittedName>
    </protein>
    <gene>
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    </gene>
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        <name type="scientific">Lysobacter enzymogenes</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="438" mass="45863" checksum="D488886F5EB6B53A" modified="2016-02-17" version="1">MIRPHAAAPLALAVLSCLFAAAAQAAPTPAEPTALRCGKLFDARSGKLLGAHTITVRDGKIAQVQAGLNDVAGARAVDLSQHTCTPGWTDLHVHLGGQSSAQSYSEGFRLDPVDFAFRAVGYANKTLMAGFTSVRDLGGEVSPHLRDAINQGLVSGPRIWAAGKSIATTGGHADPTNGMNDALSHLIGPPGPTEGVINSIDDARQAVRQRYKEGSDVIKITATGGVLSYAKSGDAPQFTVDEVKAIVDTAKDYGYRVAAHAHGEEGMKRAVLGGVTSIEHGTYMSPEVMSLMKQRGTWYVPTVYAGRFVADKAKIDGYFPDVVRPKAARIGAMIQQTAASAYKNGVKIAFGTDMGVGPHGDNAREFVYMVEAGIPAAVALQAATIRAAEVLGVEDQGTIETGKRADIVAVKGDPIADINAVLDVAFVMKDGTVYKQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKJ0</accession>
    <name>A0A0S2DKJ0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3719</name>
    </gene>
    <organism evidence="1 2">
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        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59063">
        <property type="protein sequence ID" value="ALN59063"/>
        <property type="gene ID" value="GLE_3719"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="40" mass="4811" checksum="DA74E335CA3238E2" modified="2016-02-17" version="1">MACVYYFLSLLYKEVNSCLRKYICKTSFISVLQRKLLKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKM4</accession>
    <name>A0A0S2DKM4_LYSEN</name>
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        <recommendedName>
            <fullName evidence="6">UPF0761 membrane protein GLE_3830</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rbn</name>
        <name evidence="7" type="ORF">GLE_3830</name>
    </gene>
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        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UPF0761 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN59173">
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    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Virul_fac_BrkB"/>
    </dbReference>
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        <property type="entry name" value="PTHR30213"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="yihY_not_rbn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
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        <location>
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            <end position="62"/>
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            <end position="203"/>
        </location>
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            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="420" mass="46721" checksum="69F62F22F2C21E61" modified="2016-02-17" version="1">MDSIYRWSDRVRDRARVGTFFRFLARRFLDDNLFQAAGALSYTTVFALVPLSMVVFGVLSAFPMFGEWSDKLSDYIFSNFVPSAARSVESYLKQFSANAGQLTAAGVIALVVSLLITLNGVESAFNQIWRVHSARPRIGRFLIYWTVLTLGALLAAASLAISARFFALDVFATQPGRWLESLLLRGAPMALEWLAFAAIYVVVPHRTVKWRHAVAGAFLAMVLFEVIKGGIGLYLGSFGSYSKIYGTLAFVPIFLLWIYLSWIAVLLGASLASSIAAFRYQPAAMRLPLGFEMYGLLRLLARFAQARKRGRGLHIDDIQQLEPMLTDSLVQQMLEQLGEIQVVSRAESGEWLLSRDLDELSLGELYEACNLRIPIAEAMLPCRDDSLGQSAVAAMDELRVPLRALMKRRVSSIHAEEDAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKP3</accession>
    <name>A0A0S2DKP3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endo-beta-N-acetylglucosaminidase H</fullName>
            <ecNumber evidence="3">3.2.1.96</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_17950</name>
        <name evidence="3" type="ORF">GLE_3649</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.96" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3649"/>
    <dbReference type="EnsemblBacteria" id="ALN58993">
        <property type="protein sequence ID" value="ALN58993"/>
        <property type="gene ID" value="GLE_3649"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3649"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3593"/>
    <dbReference type="OMA" id="NAGWSCN"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033925">
        <property type="term" value="F:mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726675" evidence="1">
        <location>
            <begin position="24"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="2">
        <location>
            <begin position="23"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="289" mass="30769" checksum="FA83BE042F208465" modified="2016-02-17" version="1">MFGKSALLAVGLMAFFGVGEASARNVVFLNNPSPQDVKDVGKYLVSGTGQPFFSDLVLFAANINGSTPNTPVLYYNAEMSAILKDNLSIVRGLQAQGIKVQISYLGNHQNAGWSCNMSSAAATKLANAMVADVVKYGLDGISVDDEYSQCSGNAKAFYSVLKAIRANSKFAGKTLSKALWSDSSYFRSPSNAADYLTEGYEMTYAGSVSYLAPYVGYGMSKNALFLGISPQFSPASSVRSIAQDVEDDGYQGVMIWAPNAFLDTASASAYYTQIVKAQAGEAESVEYVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL81</accession>
    <name>A0A0S2DL81_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3996</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59338">
        <property type="protein sequence ID" value="ALN59338"/>
        <property type="gene ID" value="GLE_3996"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3996"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="129" mass="14594" checksum="5ABF1D8A4F5DB503" modified="2016-02-17" version="1">MFGAVGLQKTPLDRKKALFARGCRRCIDASTTMFAIRSKRTPHGALRCRLRECVVHVLAASDIALCAIRRAGREAYHDSSIVIRLKPSIASASRRSRLLDRTLDRRHFRLITWEIMALNIAGPRLAREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLA6</accession>
    <name>A0A0S2DLA6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4023</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59365">
        <property type="protein sequence ID" value="ALN59365"/>
        <property type="gene ID" value="GLE_4023"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4023"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3960"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="83" mass="9564" checksum="6BEC52FF17CFD9F8" modified="2016-02-17" version="1">MIAEAAKQDEWERRERERRERDDAKKVAAGAVGIAVVAGVIAASAKRERENRERADYCASRYGNYDRRNDTYRGSDGYTYNCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLN2</accession>
    <name>A0A0S2DLN2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cell envelope integrity protein TolA</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Protein TolA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tolA</name>
        <name evidence="4" type="ORF">BV903_01155</name>
        <name evidence="5" type="ORF">FE772_19905</name>
        <name evidence="3" type="ORF">GLE_4054</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000002">
        <property type="protein sequence ID" value="OPD65888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948746.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4054"/>
    <dbReference type="EnsemblBacteria" id="ALN59396">
        <property type="protein sequence ID" value="ALN59396"/>
        <property type="gene ID" value="GLE_4054"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65888">
        <property type="protein sequence ID" value="OPD65888"/>
        <property type="gene ID" value="BV903_01155"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4054"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3997"/>
    <dbReference type="OMA" id="TAREDGW"/>
    <dbReference type="OrthoDB" id="1818842at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD65888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW27568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="319" mass="34984" checksum="5FB13ECAAAE9AB5F" modified="2016-02-17" version="1">MRETRADSVQAAILVVLLHGLLIAALIVSALLNWNSGAVSAAGSPVSTELAEMSDLSAAMQRTLRSKVEPVPQPQPEPEPEEAEPLPQPVAEPKPQDAVSPQQQSPQDFIPVPDATSQEQVVDTPTPNPAEDKKLQDAKARQEQVDLTEQKRQEEAQQKQRLAEQQEAERQKKLEEIRRERARLQREQNLAEQKLQQLADRRASQASQTAAATAPAQQAGNQGTDTGLLARYQAALQSAIKNKWTRPDSVPLGAACRLNIRQLPGGQVIAVEVIEPCAYDEAGRRSVEAAVLKAQPLPYAGFESVFQRSLILNFRAEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLR2</accession>
    <name>A0A0S2DLR2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_19970</name>
        <name evidence="2" type="ORF">GLE_4068</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948759.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4068"/>
    <dbReference type="EnsemblBacteria" id="ALN59410">
        <property type="protein sequence ID" value="ALN59410"/>
        <property type="gene ID" value="GLE_4068"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4068"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4011"/>
    <dbReference type="OMA" id="QFFFVYF"/>
    <dbReference type="OrthoDB" id="1526822at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="176" mass="19365" checksum="807D911236C529AF" modified="2016-02-17" version="1">MSANFRIRRAAPADTAALADISARSFVETFGDSYPPDDLSRFLAETYSHDAIGALLADPRYGAWLLERDGVAVGHALAGECGLPHAEVAPGDGELKRLYVLGEAQNGGWGGRLFETALAWLERDGPRTLWIGVWSENYGAQRFYGRHGFEKVGHYEFVVGATRDHEFILRRSAAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLX2</accession>
    <name>A0A0S2DLX2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Probable peptidoglycan glycosyltransferase FtsW</fullName>
            <shortName evidence="7">PGT</shortName>
            <ecNumber evidence="7">2.4.1.129</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Cell division protein FtsW</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Cell wall polymerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Peptidoglycan polymerase</fullName>
            <shortName evidence="7">PG polymerase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">ftsW</name>
        <name evidence="10" type="ORF">BV903_07595</name>
        <name evidence="9" type="ORF">GLE_4132</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">B25</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Peptidoglycan polymerase that is essential for cell division.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <text evidence="7">Localizes to the division septum.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the SEDS family. FtsW subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.129" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000015">
        <property type="protein sequence ID" value="OPD64519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948811.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4132"/>
    <dbReference type="EnsemblBacteria" id="ALN59474">
        <property type="protein sequence ID" value="ALN59474"/>
        <property type="gene ID" value="GLE_4132"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64519">
        <property type="protein sequence ID" value="OPD64519"/>
        <property type="gene ID" value="BV903_07595"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4132"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4074"/>
    <dbReference type="OMA" id="KLWWSNL"/>
    <dbReference type="OrthoDB" id="1133883at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00913">
        <property type="entry name" value="PGT_FtsW_proteobact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013437">
        <property type="entry name" value="FtsW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001182">
        <property type="entry name" value="FtsW/RodA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474">
        <property type="entry name" value="PTHR30474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01098">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02614">
        <property type="entry name" value="ftsW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="316"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="352"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="393"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="415"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN59474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD64519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="429" mass="45861" checksum="4441ADA0A98BE36B" modified="2016-02-17" version="1">MENTARQATRLEAIHGRYDPWLLAASAALACVGVIMVGSASLGVANTHEVDPFYFLTRHLMFLAIGLGLAFWLMRTELKTIEQHNQWLLLVCVVLLVAVFIPGIGRQVNGAKRWINLAVIGFQAVEAVKLLYIVWLASYLKRFSEDISATWGAMLKPIGVAVVLVGLLLMQPDFGSSSLLLAITAGMLVLGGVNMPRMFGPVLIGLPVLAVIAIAEPYRVIRLTSFMNPWSDPFGTGYQLTNALMAVGRGEWTGVGLGASVQKLQYLPEAHTDFIMAVIAEEFGFAGVCAVVGLYALLAGRALWTGLKCVEMRRHFSGYVAFGIALWMSLQSFVSIGVNLGLLPTKGLTLPMISYGGSSILMSCAALGVLLRVSYELDRAQRQVARLRGEAAGSAPATASPAPAAAAAGAARGTSRLRDRVEPSLGRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM10</accession>
    <name>A0A0S2DM10_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">4-hydroxyphenylpyruvate dioxygenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">4-hydroxyphenylpyruvate dioxygenase SEQUENCING GAP</fullName>
            <ecNumber evidence="7 8">1.13.11.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hppD</name>
        <name evidence="8" type="ORF">FE772_21065</name>
        <name evidence="7" type="ORF">GLE_4305</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="5">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the 4HPPD family.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.27" evidence="7 8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948949.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4305"/>
    <dbReference type="EnsemblBacteria" id="ALN59646">
        <property type="protein sequence ID" value="ALN59646"/>
        <property type="gene ID" value="GLE_4305"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4305"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4244"/>
    <dbReference type="OMA" id="DPFPVKG"/>
    <dbReference type="OrthoDB" id="402639at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003868">
        <property type="term" value="F:4-hydroxyphenylpyruvate dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009072">
        <property type="term" value="P:aromatic amino acid family metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07250">
        <property type="entry name" value="HPPD_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08342">
        <property type="entry name" value="HPPD_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005956">
        <property type="entry name" value="4OHPhenylPyrv_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041735">
        <property type="entry name" value="4OHPhenylPyrv_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041736">
        <property type="entry name" value="4OHPhenylPyrv_dOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11959">
        <property type="entry name" value="PTHR11959"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009283">
        <property type="entry name" value="HPP_dOase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01263">
        <property type="entry name" value="4HPPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="VOC" evidence="6">
        <location>
            <begin position="170"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR009283-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW27765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="363" mass="40422" checksum="88DF6D01A73C8763" modified="2016-02-17" version="1">MNAQPNLGMQVTTFENPLGIDGFEFVEFAAPKGQGALLHDYFRKLGFSAVLKHKSRPVTVYRQGGVNFLVNETPDSFASAFAEAHGPCASGFAIRFKQPAGEVLKAVLANGGEAVTDRADTRVIDAPVVKGIGDCMLYLVDQYGDKGDAYADYEPIAGAEQNPTGFGLTFIDHLTHNLYFGNMQKWSDYYERLFNFREIKYFDIKGAKTGLVSKAMTAPDGIVRIPLNESNDPKSQINEYLDAYKGEGIQHIACFTDNIYDTVEAMRAQGVEFLDTPDTYFDVIDMRVPNHGEDVPRLAKNKILIDADPETHQRKLLQIFTQNAIGPIFFEIIQRKGNEGFGEGNFQALFESIERDQMKRGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMI2</accession>
    <name>A0A0S2DMI2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid/peptide transporter (Peptide:H+ symporter)</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BV903_18565</name>
        <name evidence="9" type="ORF">FE772_21075</name>
        <name evidence="7" type="ORF">GLE_4308</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000051">
        <property type="protein sequence ID" value="OPD62422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948950.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000051.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4308"/>
    <dbReference type="EnsemblBacteria" id="ALN59649">
        <property type="protein sequence ID" value="ALN59649"/>
        <property type="gene ID" value="GLE_4308"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62422">
        <property type="protein sequence ID" value="OPD62422"/>
        <property type="gene ID" value="BV903_18565"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4308"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4247"/>
    <dbReference type="OMA" id="ATKFFEA"/>
    <dbReference type="OrthoDB" id="470322at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904680">
        <property type="term" value="F:peptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006857">
        <property type="term" value="P:oligopeptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17346">
        <property type="entry name" value="MFS_DtpA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005279">
        <property type="entry name" value="Dipep/tripep_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018456">
        <property type="entry name" value="PTR2_symporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="PTHR11654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00924">
        <property type="entry name" value="yjdL_sub1_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01023">
        <property type="entry name" value="PTR2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0571">Peptide transport</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="345"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="407"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="442"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="485"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD62422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW27767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="512" mass="55381" checksum="B5ED5B850B7DFA6E" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMJ7</accession>
    <name>A0A0S2DMJ7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_4324</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948962.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4324"/>
    <dbReference type="EnsemblBacteria" id="ALN59665">
        <property type="protein sequence ID" value="ALN59665"/>
        <property type="gene ID" value="GLE_4324"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4324"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4263"/>
    <dbReference type="OMA" id="RIWMNLP"/>
    <dbReference type="OrthoDB" id="2030110at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="PTHR11727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="210" mass="22964" checksum="3B81B0B5D13EDC43" modified="2016-02-17" version="1">MSQPLSPAARAAAVPARGDYWSFLRSWSRAPGRVGAIAPSGAALARLITAQIDADTGPVLELGPGTGVFTRALLERGVAERDLTLVEYGPEFAQMLGERFPQARVLCADARRLRRARLFGEDGAGAVVSGLPLRNLPPRQRLAVLLGAFAQLGEDGAYYQFTYGLSFPLPRAWLERYGFKVQRLGAARLNLPPASVYRVTRRRDWRLMGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMR2</accession>
    <name>A0A0S2DMR2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_4455</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
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        <property type="protein sequence ID" value="ALN59796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4455"/>
    <dbReference type="EnsemblBacteria" id="ALN59796">
        <property type="protein sequence ID" value="ALN59796"/>
        <property type="gene ID" value="GLE_4455"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4455"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4392"/>
    <dbReference type="OMA" id="ATTLMTQ"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="338" mass="36555" checksum="117F6DDDB387E4AB" modified="2016-02-17" version="1">MVLATLALGYTLWAAQELLLPILLAAFFALVGNPILRLLGKLRLPRLLGALIVMVGGLAVAGALTLQLAEPAGEWVRQVPKELKQVGPKLRQMTKPFQDANRAAQNFARAAGGENTARPVQVVKTELDDPYRALTSTPKRLAQVLAVVLLTFFFMVFGESLQRNAIALLPSQQKKKLTIDILHSIEREISRYVLTISLINTGLGLALAGALYALGTPLQEALLWGTMAALLNFAPFVGPLIGVAVMLVMGLVAFDQLGPSLLPAGLYLGLHTIESQVVTPLVLGRRMRLSPLVLMLALMFFGWLWGIVGLLLAVPLLVCVKLVLARIEGLEGWARLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMU4</accession>
    <name>A0A0S2DMU4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_20850</name>
        <name evidence="2" type="ORF">GLE_4258</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948910.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59599">
        <property type="protein sequence ID" value="ALN59599"/>
        <property type="gene ID" value="GLE_4258"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4258"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4198"/>
    <dbReference type="OMA" id="NECEIIS"/>
    <dbReference type="OrthoDB" id="2055010at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="15"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="172" mass="18782" checksum="E169E86754DEA5EF" modified="2016-02-17" version="1">MDSHVPSTAPATEPTALHALKPGDRDAVRAFLRQRWNSATILLDGRAIDAAALPGFLARDAGGIAALITLLDESEHCEIVTLDAVRPYAGLGTALIERAAQRARALGLRRLLTRTTNDNLDALRFYQRRGFRLHRLVPGAIDLEREADPTIALIGRHGIPLRDEISLIRGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMW7</accession>
    <name>A0A0S2DMW7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SRPBCC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_21420</name>
        <name evidence="1" type="ORF">GLE_4384</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949010.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4384"/>
    <dbReference type="EnsemblBacteria" id="ALN59725">
        <property type="protein sequence ID" value="ALN59725"/>
        <property type="gene ID" value="GLE_4384"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4384"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4323"/>
    <dbReference type="OMA" id="HARWEFA"/>
    <dbReference type="OrthoDB" id="1719670at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019587">
        <property type="entry name" value="Polyketide_cyclase/dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10604">
        <property type="entry name" value="Polyketide_cyc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="165" mass="18286" checksum="326440493E9ED949" modified="2016-02-17" version="1">MRLSLTAERRIDAPPEAVFALALDSDRFPALFPGYGPIPALVRITALAPPAVGALRSLESSDGSRLMERITALEPPHLHAYTLDGLRPPLAWLARAGHARWEFAADRSDGGDATRVAWRYDFELTSALAWPLAAPLLRGCMRAAMRRCLERMAQALEGAWREERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMX7</accession>
    <name>A0A0S2DMX7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Flagellar basal-body rod protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">flgB</name>
        <name evidence="2" type="ORF">BV903_14255</name>
        <name evidence="3" type="ORF">FE772_22595</name>
        <name evidence="1" type="ORF">GLE_4634</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000036">
        <property type="protein sequence ID" value="OPD63289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949199.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4634"/>
    <dbReference type="EnsemblBacteria" id="ALN59975">
        <property type="protein sequence ID" value="ALN59975"/>
        <property type="gene ID" value="GLE_4634"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63289">
        <property type="protein sequence ID" value="OPD63289"/>
        <property type="gene ID" value="BV903_14255"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4634"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4570"/>
    <dbReference type="OrthoDB" id="2070652at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0966">Cell projection</keyword>
    <keyword evidence="1" id="KW-0969">Cilium</keyword>
    <keyword evidence="1" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD63289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="121" mass="12794" checksum="2C34348AD1BA617F" modified="2016-02-17" version="1">MTSPVLEAIVSKALDGLHLREIATSHNVANASSPGFVPVRVSFEGQLQELAQATAAMAPPQRAAELSALQPRVAASADPAERSVKIDQEIAIASETSARYAMLIGMLNRSLQMQQLAIRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN78</accession>
    <name>A0A0S2DN78_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_21955</name>
        <name evidence="2" type="ORF">GLE_4496</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949100.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59837">
        <property type="protein sequence ID" value="ALN59837"/>
        <property type="gene ID" value="GLE_4496"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4496"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4433"/>
    <dbReference type="OrthoDB" id="2127438at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726819" evidence="1">
        <location>
            <begin position="22"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="165" mass="17550" checksum="4DA841807D52F15C" modified="2016-02-17" version="1">MSRRTLAFCAFLIAALLAADAAAKNKVTRQLGGACGEDANTIAQCDVGMSCKDGYCAMNSYLSEASRSCKDLMIKAGVVGARETVSVHDGFCYKHCDGMYELAMEATPVTERLMHHARVGSKEFGEEVAKLSDSEKATFKAAESKCNSCGKQCTIGSSFLGRGGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNA2</accession>
    <name>A0A0S2DNA2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA polymerase sigma-E factor, ECR family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Sigma-70 family RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">D9T17_05995</name>
        <name evidence="6" type="ORF">FE772_22750</name>
        <name evidence="5" type="ORF">GLE_4671</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">OH11</strain>
        </source>
    </reference>
    <reference evidence="6 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 10">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000019">
        <property type="protein sequence ID" value="ROU07759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949227.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4671"/>
    <dbReference type="EnsemblBacteria" id="ALN60012">
        <property type="protein sequence ID" value="ALN60012"/>
        <property type="gene ID" value="GLE_4671"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4671"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4607"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="3">
        <location>
            <begin position="28"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="4">
        <location>
            <begin position="132"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW28040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROU07759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="194" mass="21873" checksum="31EAB96E33B14349" modified="2016-02-17" version="1">MTGNPAPTDDRALVDAVLSRQPGAFERLVREYQGLCWHIIQRMVRHPDDTRELCQEAFLRVHQCLHQYRHESALKSWIGQVAYSVAKRHLERKRIPIVEAAADEDALSPLEAVSDGFDLEAACADEEIAAGLHAEIEALPPLQRTLLTLYHLEEVPIGEIAQMTGLAEGTIKSHLFRTRARLRQRLEARLGEIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNM3</accession>
    <name>A0A0S2DNM3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4833</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4833"/>
    <dbReference type="EnsemblBacteria" id="ALN60174">
        <property type="protein sequence ID" value="ALN60174"/>
        <property type="gene ID" value="GLE_4833"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4833"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4764"/>
    <dbReference type="OMA" id="PQWVWST"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595897" evidence="2">
        <location>
            <begin position="30"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="454" mass="49196" checksum="9125934E78E04197" modified="2016-02-17" version="1">MPQTFHTFAAGARAPALPLLAAALTLALAACGDGNVKPEAAAQATAQQRWNDGPPPPPLSPTIPQDVSVPQANPDLQDLQDDFDLLSWQSFVAVNWPAGPDGNPNTGATIGPDVPTVWENWKESREIFLPGGATPPPWGQDTPPPAVCKGLGDATLRLTQVGKTPNVLDESGEPFETGPLIDQNGQYVRFAILTNRDMFDNIVANGLYSTAGQKKFGKPANFALPKGSPKVGAIMIKSAWKVLGANDNAARFHTAKALVYTNPDENEGVQAACKLQTMGLVGLHIAHKTQSAPQWVWSTFEHVDNVPTQGEPIDKPRYNFFDKNCTTCQVNQPPPRPWNPNNPHTVPTQVMREIPLTDSTKRLNATYQALLQKNYPGTVWANYELISTQWPTKANNPIDPTGNPAPSFLANATLETYIQGRVPQASSSCMACHNNATMNNQLPSDFTYLLQRAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNV6</accession>
    <name>A0A0S2DNV6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator, Rrf2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4985</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60326">
        <property type="protein sequence ID" value="ALN60326"/>
        <property type="gene ID" value="GLE_4985"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4985"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4912"/>
    <dbReference type="OMA" id="FDIAYNA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000944">
        <property type="entry name" value="Tscrpt_reg_Rrf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33221">
        <property type="entry name" value="PTHR33221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02082">
        <property type="entry name" value="Rrf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00738">
        <property type="entry name" value="rrf2_super"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51197">
        <property type="entry name" value="HTH_RRF2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="171" mass="18113" checksum="260FDE6EFC292B49" modified="2016-02-17" version="1">MLTMKAKYALRAMCALARAESGRTAPAVRHGRLQAKAIAEHSGAPSKFLESILVDLREAGFIHSRRGQKGGHTLARPADQIMVGDLIRAIDGPLAPVRCASVSAYQPCADCADPDACSLRALMREARDALSHVLDRRSLRELALAPDFGAAAIDPALLDATFLSGELGGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP00</accession>
    <name>A0A0S2DP00_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_24725</name>
        <name evidence="1" type="ORF">GLE_5102</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949555.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60443">
        <property type="protein sequence ID" value="ALN60443"/>
        <property type="gene ID" value="GLE_5102"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5102"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5027"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="154" mass="16635" checksum="6DEF3CBA8C604D18" modified="2016-02-17" version="1">MSSQANTAADGRQFIDQLEASLREQPNLDAADRDFLLKHFRDAFENAEAGGRGFDRQAWADSVAELGLGQAEQEALLGKFDQAFGGQDNEARDLGEEFVRRLARDGEAGAHAWLHEQIGQIKRSRGAAAAVQVVQGLPPQIGKVAAARKPGPWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP41</accession>
    <name>A0A0S2DP41_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent RNA helicase RhlB</fullName>
            <ecNumber evidence="5">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">rhiB</name>
        <name evidence="5" type="synonym">rhlB</name>
        <name evidence="12" type="ORF">GLE_4916</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DEAD box helicase family. RhlB subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949413.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4916"/>
    <dbReference type="EnsemblBacteria" id="ALN60257">
        <property type="protein sequence ID" value="ALN60257"/>
        <property type="gene ID" value="GLE_4916"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4916"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4846"/>
    <dbReference type="OMA" id="EYCTPIQ"/>
    <dbReference type="OrthoDB" id="626183at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00661">
        <property type="entry name" value="DEAD_helicase_RhlB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022077">
        <property type="entry name" value="RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023554">
        <property type="entry name" value="RNA_helicase_ATP-dep_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12300">
        <property type="entry name" value="RhlB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="11">
        <location>
            <begin position="9"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="40"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="231"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="422"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="6">
        <location>
            <begin position="9"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="452"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN60257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="596" mass="64322" checksum="5E9ECF531974E686" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP69</accession>
    <name>A0A0S2DP69_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">2-dehydro-3-deoxygalactonokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4619</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949187.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4619"/>
    <dbReference type="EnsemblBacteria" id="ALN59960">
        <property type="protein sequence ID" value="ALN59960"/>
        <property type="gene ID" value="GLE_4619"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4619"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4554"/>
    <dbReference type="OMA" id="RNGWIEM"/>
    <dbReference type="OrthoDB" id="1530579at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008671">
        <property type="term" value="F:2-dehydro-3-deoxygalactonokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034194">
        <property type="term" value="P:D-galactonate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007729">
        <property type="entry name" value="DGOK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042257">
        <property type="entry name" value="DGOK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042258">
        <property type="entry name" value="DGOK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05035">
        <property type="entry name" value="DGOK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="386" mass="39644" checksum="077D9CE9BEB60851" modified="2016-02-17" version="1">MNPHPFAPATAAASTRAVGAAPRAGADLGDACLDRALAHGVDPDGAQAAPTLALRGRADDAAFAPGLGRRAAAARTPPGPQIALIGVDWGPTRVRAHAFDSHGGVLATRDSARGMAGLANADEFSAALDELLGAELDDGRAPILLAGMVGARQGWQEAPYAALPADADAIAAMLQPLRFRGRHAAIVPGVCGPAVAGFDIDAAAAGFADVMRGEETQAMGVPPGTARAVAPGAHSKWLRLRAGAVVGFSSYPTGELYSLLLEQSLLGRGLPAQAWSGRGFALGLDTARAQPDWLHQLFGVRARHVRDAAPAEELPAFLSGLLIGYECLAAQAADPGEGEIAIVGDARPAAIYAQALRRYGQAHYIVEGDTAFCRGLWRIARAAGYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP76</accession>
    <name>A0A0S2DP76_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Phosphoethanolamine--lipid A transferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="10">Sulfatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FE772_23785</name>
        <name evidence="10" type="ORF">GLE_4899</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949401.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4899"/>
    <dbReference type="EnsemblBacteria" id="ALN60240">
        <property type="protein sequence ID" value="ALN60240"/>
        <property type="gene ID" value="GLE_4899"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4899"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4830"/>
    <dbReference type="OMA" id="NSGGCKG"/>
    <dbReference type="OrthoDB" id="1067869at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016772">
        <property type="term" value="F:transferase activity, transferring phosphorus-containing groups"/>
        <property type="evidence" value="ECO:0007669"/>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
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    <accession>A0A0S2DQ34</accession>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Feng T."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 6">YC36</strain>
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        <property type="entry name" value="Porin_O/P"/>
    </dbReference>
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    </dbReference>
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    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
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            <begin position="35"/>
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        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="32"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="483" mass="51846" checksum="C58A0F0C51FFF960" modified="2016-02-17" version="1">MPIQVRRRPRPFARLTAAPLWAALACAAGLPAHAAELTVEQLAQRLKAIEQRLGTAAPADAGGEGLADLDQRLRIIERKLELQAEDSAAKAASTPTVALSASKGLSIKSPPPGDVEVKFKALLQADGRFFVGDSQAPQNDTFLWRRIQPSIEGSWGSLVGFRILPEFAGDSATINDAYLDLKFDPRATLRVGKFKSPVGLERLQSSGSTGLIELGLASELTPNRDLGLQLQGEFAGSTVSYALGVFNGAVDGRDSPTANPDNEFEYAGRIFLEPWKNAGGALQGLGFGLGASAGDRAGSGNNVLPRYRTPGQSQFFNYRSTVLANGASKRWSPQLYFYRNAFGLLGEYVSSSQEVRVGAAREELDHRAWQLTAGLVLTGEDAGYRGVARPNQPFTVGSAGWGAFELVARYGRLEIDDAAFPRFADPNAVAAAARSWGLGLNWYLTANLKLVANYTQTAFDGGAANGRDREDEKAFFTRAQLAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-08-12" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ94</accession>
    <name>A0A0S2DQ94_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily MFS_1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_25705</name>
        <name evidence="7" type="ORF">GLE_5318</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949716.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60659">
        <property type="protein sequence ID" value="ALN60659"/>
        <property type="gene ID" value="GLE_5318"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5318"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5235"/>
    <dbReference type="OMA" id="IMEETHI"/>
    <dbReference type="OrthoDB" id="1108236at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="20"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN60659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW28538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="171" mass="17281" checksum="93DEFA30746C2FF8" modified="2016-02-17" version="1">MPSSNPAAAPARGRHDRFWILGAICLAGLVLPLSFTAPPVAIPAIAAELGGSPVALNWMTNAFMLAFGSCLMAAGTLADTYGRKRVFATGIVAFAAVSLLLALAPSLAALNALRVLQGVAAALALAGGNAALSQEFHGPARIRAFSLLGTAFGLGLAFGPSLAGCRRYPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQN4</accession>
    <name>A0A0S2DQN4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase, families S8 and S53/proprotein convertase P-domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_5462</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60803">
        <property type="protein sequence ID" value="ALN60803"/>
        <property type="gene ID" value="GLE_5462"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5462"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5377"/>
    <dbReference type="OMA" id="PFMTDVI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04059">
        <property type="entry name" value="Peptidases_S8_Protein_convertases_Kexins_Furin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034182">
        <property type="entry name" value="Kexin/furin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002884">
        <property type="entry name" value="P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01483">
        <property type="entry name" value="P_proprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51829">
        <property type="entry name" value="P_HOMO_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="P/Homo B" evidence="5">
        <location>
            <begin position="487"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="8"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN60803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="616" mass="64158" checksum="6ACE58F29A59B2A4" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQR2</accession>
    <name>A0A0S2DQR2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5376</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949759.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60717">
        <property type="protein sequence ID" value="ALN60717"/>
        <property type="gene ID" value="GLE_5376"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5376"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5291"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="78" mass="8784" checksum="A36A231DE673AD60" modified="2016-02-17" version="1">MNIYKNLMFLHGHFVDPRDADDDERPAAPAPAQRPAAYVPASRPAQAAPRADWRRWWLRLWPAQSARVEAGCDGARCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQV0</accession>
    <name>A0A0S2DQV0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidase, M28 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_5275</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5275"/>
    <dbReference type="EnsemblBacteria" id="ALN60616">
        <property type="protein sequence ID" value="ALN60616"/>
        <property type="gene ID" value="GLE_5275"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5275"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5193"/>
    <dbReference type="OMA" id="VNLDMPI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="PTHR12147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595989" evidence="2">
        <location>
            <begin position="22"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="3">
        <location>
            <begin position="151"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M28" evidence="4">
        <location>
            <begin position="309"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="556" mass="59020" checksum="1A4D50463745771A" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA25</accession>
    <name>A0A0S2DA25_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_01110</name>
        <name evidence="2" type="ORF">GLE_0035</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945746.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55394">
        <property type="protein sequence ID" value="ALN55394"/>
        <property type="gene ID" value="GLE_0035"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0035"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.42"/>
    <dbReference type="OMA" id="SSEEWNF"/>
    <dbReference type="OrthoDB" id="1975784at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726639" evidence="1">
        <location>
            <begin position="19"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="78" mass="8651" checksum="77359EBA18FF4DB7" modified="2016-02-17" version="1">MNVWVQLAIWLVSYFVSAAARPKPPQPKPAAFGDFQFPQATEGTPQAVIFGDVWISDWMVLGVGQYRTQAIKQKGGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAA9</accession>
    <name>A0A0S2DAA9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="6">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">GTP cyclohydrolase I</fullName>
            <shortName evidence="6">GTP-CH-I</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">folE</name>
        <name evidence="9" type="ORF">BV903_05625</name>
        <name evidence="10" type="ORF">FE772_01275</name>
        <name evidence="8" type="ORF">GLE_0069</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17473"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="EC" id="3.5.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homopolymer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000010">
        <property type="protein sequence ID" value="OPD64967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945772.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0069"/>
    <dbReference type="EnsemblBacteria" id="ALN55428">
        <property type="protein sequence ID" value="ALN55428"/>
        <property type="gene ID" value="GLE_0069"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64967">
        <property type="protein sequence ID" value="OPD64967"/>
        <property type="gene ID" value="BV903_05625"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0069"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.75"/>
    <dbReference type="OMA" id="CEHMCMS"/>
    <dbReference type="OrthoDB" id="1632367at2"/>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035998">
        <property type="term" value="P:7,8-dihydroneopterin 3'-triphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00223">
        <property type="entry name" value="FolE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018234">
        <property type="entry name" value="GTP_CycHdrlase_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="PTHR11109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00063">
        <property type="entry name" value="folE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00859">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00860">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GTP_cyclohydroI" evidence="7">
        <location>
            <begin position="14"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN55428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD64967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW24508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="197" mass="22012" checksum="7A69BF623BE93514" modified="2016-02-17" version="1">MADTPDKPSREQAEAAVRTLLAWAGEDPSREGLLDTPKRVVTAYGDWFSGYDDDPREYLARTFEEVAGYDEMIVLRDIEFESHCEHHMAPIIGKAHVGYLPSGKVVGISKLARVVETYARRFQVQEKMTAQIAQSIQDVLQPLGVGVVVEGAHECMTTRGVHKRGVSMITSKMLGMFRDDARTRAEFLRFIDVGPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAD0</accession>
    <name>A0A0S2DAD0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sec-independent protein translocase protein TatB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">tatB</name>
        <name evidence="11" type="ORF">GLE_0123</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TatB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0123"/>
    <dbReference type="EnsemblBacteria" id="ALN55482">
        <property type="protein sequence ID" value="ALN55482"/>
        <property type="gene ID" value="GLE_0123"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0123"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.126"/>
    <dbReference type="OMA" id="IGFWELA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033281">
        <property type="term" value="C:TAT protein transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00237">
        <property type="entry name" value="TatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003369">
        <property type="entry name" value="TatA/B/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018448">
        <property type="entry name" value="TatB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02416">
        <property type="entry name" value="TatA_B_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01410">
        <property type="entry name" value="tatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="67"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN55482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="180" mass="19251" checksum="59CC5592D4D32E36" modified="2016-02-17" version="1">MFDIGFSEVFVIAIVALIVLGPERLPKAARFAGLWVRRARAQWYSVKSELERELADDELKRSLRQAQDDLRSAQQQLRDGDRALREGVDDLNRRVAGTGAAATAADDAAAAPRDPAALEDQALGDGASNGAASDRAAAYAAPAHAAADTAHAEPSHLDYSGASQPDYRPSTAQTPNDERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAF2</accession>
    <name>A0A0S2DAF2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0138</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55497">
        <property type="protein sequence ID" value="ALN55497"/>
        <property type="gene ID" value="GLE_0138"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0138"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="62" mass="7104" checksum="2A889B52FD576322" modified="2016-02-17" version="1">MRRGAIRYRGDLHPESLRQPRVFFAVVRMVDLMTGGIADEVDGVANFMRIVRWAGFVQLIRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAJ8</accession>
    <name>A0A0S2DAJ8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">LysR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_01945</name>
        <name evidence="3" type="ORF">GLE_0221</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945880.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0221"/>
    <dbReference type="EnsemblBacteria" id="ALN55580">
        <property type="protein sequence ID" value="ALN55580"/>
        <property type="gene ID" value="GLE_0221"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0221"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.223"/>
    <dbReference type="OMA" id="ECGSLDW"/>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="16"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="322" mass="35533" checksum="C176CB14584CE708" modified="2016-02-17" version="1">MTSTRSLSPRFAYKSDKLKPLRAFCQTARLGSVSRAAEALYLSQPAVTLQLQALEREMGVRLLERSGRRLALTREGEALYELARPLVEGLDGLEGVFRERIRGLDAGELNVAAGSSTILYLLPKIVEAFRAAHPEVRLTLHNVTGAGGLDLLRSDGVDLAVGSMLDVPGDLSYAPVYRFEPMLIAPRDHPLATLETLTLQDLSPYGLILPPQRLTTYRMVDLVFQQNRVPYTVALEVGGWEVIKQYVAMGLGISIVTAICLTEADRARLSARSLADYFPSRSYGVVVRKGKYLSPQARAFTELIQPALFERGDYYATGQSDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAL3</accession>
    <name>A0A0S2DAL3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Guanyl-specific ribonuclease Sa3 (RNase Sa3)</fullName>
            <ecNumber evidence="5">3.1.27.3</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Ribonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_01305</name>
        <name evidence="5" type="ORF">GLE_0078</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribonuclease N1/T1 family.</text>
    </comment>
    <dbReference type="EC" id="3.1.27.3" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945778.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0078"/>
    <dbReference type="EnsemblBacteria" id="ALN55437">
        <property type="protein sequence ID" value="ALN55437"/>
        <property type="gene ID" value="GLE_0078"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0078"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.83"/>
    <dbReference type="OMA" id="DPPEAWY"/>
    <dbReference type="OrthoDB" id="1964970at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000026">
        <property type="entry name" value="Gua-sp_ribonuclease_N1/T1/U2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016191">
        <property type="entry name" value="Ribonuclease/ribotoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00545">
        <property type="entry name" value="Ribonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53933">
        <property type="entry name" value="SSF53933"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN55437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW24514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="144" mass="15832" checksum="185DB2383828615D" modified="2016-02-17" version="1">MRRPLWLIPVVALLALWLWSQQGARQPTGDSGASAPVAVSAGDGLATSAPAFLPAEARDVLRRIADGGPFAHRQDGSTFQNRERRLPAQARGYYREYTVETPGSGDRGARRIVTGGDPPSEYYYTDDHYRSFRRFDPPAQGAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAP4</accession>
    <name>A0A0S2DAP4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_01475</name>
        <name evidence="3" type="ORF">GLE_0110</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945802.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55469">
        <property type="protein sequence ID" value="ALN55469"/>
        <property type="gene ID" value="GLE_0110"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0110"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.113"/>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55469.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW24540.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="212" mass="23090" checksum="9964220FA215866A" modified="2016-02-17" version="1">MTTTDDTTASAAPAASPAAPPAGWWRRNASWLAGTAVLGALALWLPYRDALRQYRLLNPSIAVAANKHDWTAFAGARWKLVAAESVPARDPRLRGPLRKDAEVVLLRYEVIPDSGTKTVDLDGCRGAIVDAQGRRWDTGGAALPRLSGPRLPETCGSGYDDAFKQVLAVPGRPFAFQHAFVLPRGQRLEDLRARIEMKRSETVGGRYLEFAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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    </comment>
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    </dbReference>
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        <property type="gene ID" value="GLE_0278"/>
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    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="231" mass="24837" checksum="16CC698AB2882556" modified="2016-02-17" version="1">MFVAIPSRERARLRWATPLLFALLWICFIVSAVVLPDPEQRRLMLEWGALSGGLSSPEAWWDAVREGSLLRLFSALFLHADWAHLLGNLVFLLIFGLPAERAMGPWRLLALFLCGGAVANLAAVIAIATPDRLIIGASGAVSALIGAYLALFPGAKLGVVVPLGLFLQFVKVPAPLLIGVWALLQVVFTFIGPAFGAVAWSAHLAGFAFGGAFALIARAGIARRLRRKRGY</sequence>
</entry>
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    <accession>A0A0S2DBE0</accession>
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        </submittedName>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        <property type="protein sequence ID" value="ALN55842"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN55842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW24821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="600" mass="62715" checksum="10834D4FE38FCFAE" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBE2</accession>
    <name>A0A0S2DBE2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
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    </protein>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55777">
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        <property type="gene ID" value="GLE_0419"/>
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    <dbReference type="KEGG" id="lez:GLE_0419"/>
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    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="288" mass="30621" checksum="276EA4FE1379B587" modified="2016-02-17" version="1">MLEDGRAVRGSWQNAASERAARERGVPRHGRNGWNGRFCGAASGGHSLYRRTAHGGIDKARRRGRCGRGRKPRPMRGVTPIPYPAAMQNLAAHDYADGHVIHLVSKLQPAPGQAPAALGLPRRLGPAGRAWFALANTVVSAAAAGALFLLWTRPTPGLWFQLLFTVMLVGLAAAPWAILAGSIRQADFERGLQATWRDIAGRASAVEARVIERDWTLSEDGSVASFALTVRTADAASLRGRWRPADASHGLLQAQVPGVGAVVRVWRVADAPAGAPRVIEAADPSVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBI5</accession>
    <name>A0A0S2DBI5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GNAT family N-acetyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_03360</name>
        <name evidence="2" type="ORF">GLE_0528</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0528"/>
    <dbReference type="EnsemblBacteria" id="ALN55886">
        <property type="protein sequence ID" value="ALN55886"/>
        <property type="gene ID" value="GLE_0528"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0528"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.523"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038740">
        <property type="entry name" value="BioF2-like_GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13480">
        <property type="entry name" value="Acetyltransf_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Acetyltransf_6" evidence="1">
        <location>
            <begin position="183"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="356" mass="39408" checksum="3ECC3DD57E75263E" modified="2016-02-17" version="1">MKPRIEVFDSLERVDRRSYQTLHDASRASLFYDWRFLLAAERSPLLPTQKTLYLCAYDGDELAGCLPAYLQRLAAVDPLGLLARAAQVRDAGGESGLFSHMMHCWDSSVPCLETAGGVREALLDALLDVAAREGAAYAGLLNLGEAARAGGSRLRLHPLVERYDAQLGLFDDFDHYVRALPSDGRAEMRRQLRKFEASGASAQVLAPPFDDRLEQVCELCFRTTARRGTPHYFPAAPLARFVRLCGDLARLVLIQAQGRVISGMIGWQRRDTFCLWSAGVTYDQSDFSPYTICFAAAFRHAFAHGLQRFEGGRLNERIKRRLGLSPVPLRCAIARLAPPRRAAPTSARVPASAALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBL8</accession>
    <name>A0A0S2DBL8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two-component system response regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_0569</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0569"/>
    <dbReference type="EnsemblBacteria" id="ALN55927">
        <property type="protein sequence ID" value="ALN55927"/>
        <property type="gene ID" value="GLE_0569"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0569"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.563"/>
    <dbReference type="OMA" id="NVLRKTQ"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="133"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN55927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="204" mass="22244" checksum="405629FD074D526A" modified="2016-02-17" version="1">MFIVDDQPLVRHGLRWILGAHSDIDVVGEAGDPHEAVQRLDQSAADVALCGFNLPDDDGLGLVQRLLRHDPALRILIVSVVGDGPMPRRLLAAGALGYVSKTRDAAVVVRALREVAAGRRFIDDSLGGRILFESSPFDRLSPRELEVTRLMVEGRRNHEIALALRVAESTVRTLRSRALGKLDVRGEGALMRLAIDHGWVARGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBT1</accession>
    <name>A0A0S2DBT1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_03895</name>
        <name evidence="2" type="ORF">GLE_0638</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946180.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55996">
        <property type="protein sequence ID" value="ALN55996"/>
        <property type="gene ID" value="GLE_0638"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0638"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.627"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="68" mass="7491" checksum="503E66AB8899255A" modified="2016-02-17" version="1">MKSPQAQVDERGAAASPPRWRTALLRRIALTIAAKLALLTLLYLLFFSPSHRPPVDAGAVDRLLLQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBY0</accession>
    <name>A0A0S2DBY0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="12">M13 family metallopeptidase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="11">Peptidase, family M13</fullName>
            <ecNumber evidence="11">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FE772_03125</name>
        <name evidence="11" type="ORF">GLE_0474</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M13 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="11"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55832">
        <property type="protein sequence ID" value="ALN55832"/>
        <property type="gene ID" value="GLE_0474"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0474"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.470"/>
    <dbReference type="OMA" id="MHKVSDL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
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</entry>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </evidence>
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    </evidence>
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</entry>
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    <accession>A0A0S2DC68</accession>
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        <submittedName>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <source>
            <dbReference type="EMBL" id="ALN55981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="44" mass="4951" checksum="BB89C97D0F62660A" modified="2016-02-17" version="1">MPFDFMEQILLHDGPGCQTCFRFRAKTLFGTPQGAAMCHRCLSS</sequence>
</entry>
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    <accession>A0A0S2DCA1</accession>
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        </submittedName>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="119" mass="12796" checksum="D8395B7DFBC6AFA0" modified="2016-02-17" version="1">MSAEPIGTELRARLDEFARQPGVTAEAARNLEAAIVRSPALTRQLNAAADSRELRHFELKSDAHAGGSAAHRRAGVAMQDALRTPVEESSRQASALPRETPTPAPVQSETQTQPQPAHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCS5</accession>
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        <name evidence="3" type="ORF">BV903_12485</name>
        <name evidence="4" type="ORF">FE772_05510</name>
        <name evidence="2" type="ORF">GLE_0981</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD63635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW25194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946436.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000030.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56339">
        <property type="protein sequence ID" value="ALN56339"/>
        <property type="gene ID" value="GLE_0981"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63635">
        <property type="protein sequence ID" value="OPD63635"/>
        <property type="gene ID" value="BV903_12485"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0981"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.969"/>
    <dbReference type="OrthoDB" id="2044103at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046256">
        <property type="entry name" value="DUF6289"/>
    </dbReference>
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        <property type="entry name" value="DUF6289"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595322" evidence="1">
        <location>
            <begin position="26"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="74" mass="7821" checksum="A53B0A8C1C5BC91D" modified="2016-02-17" version="1">MRRIGFFSAAFAVALAGTMSFAALANSWQGTWTYYNAEGAQIGRWTAGCGAADGRWGDTSGSNKRFTQGCAVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCV0</accession>
    <name>A0A0S2DCV0_LYSEN</name>
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        </submittedName>
    </protein>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD63621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946425.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000030.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0961"/>
    <dbReference type="EnsemblBacteria" id="ALN56319">
        <property type="protein sequence ID" value="ALN56319"/>
        <property type="gene ID" value="GLE_0961"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63621">
        <property type="protein sequence ID" value="OPD63621"/>
        <property type="gene ID" value="BV903_12410"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0961"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.948"/>
    <dbReference type="OMA" id="DYMLTDN"/>
    <dbReference type="OrthoDB" id="2018542at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005618">
        <property type="entry name" value="OMPW"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <location>
            <begin position="24"/>
            <end position="207"/>
        </location>
    </feature>
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            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="207" mass="22087" checksum="61C0B8BFDA911C63" modified="2016-02-17" version="1">MNHRLTGGLVAAALACAAHPALAQQAGTFTVGIGAHQVQPKSNNGSVLGGTAQLEIGDNVQPTITFEYFLRENLGIEVLAATPFKHDIDIKGLGKVATTKHLPPTFSLQYHWNSQGTVSPFVGVGVNYTTFFSEKTTGPLRGAKLKLEDSVGVAAHVGVDFILNERGAVRVDARWMDIGTDVKLNGQKIGKANIDPLVYGLAYVFKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD39</accession>
    <name>A0A0S2DD39_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_05995</name>
        <name evidence="2" type="ORF">GLE_1088</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW25279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_1088"/>
    <dbReference type="EnsemblBacteria" id="ALN56446">
        <property type="protein sequence ID" value="ALN56446"/>
        <property type="gene ID" value="GLE_1088"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
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        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="116"/>
        </location>
    </feature>
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        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="181"/>
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        <location>
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            <end position="208"/>
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        <location>
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            <end position="263"/>
        </location>
    </feature>
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        <location>
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            <end position="302"/>
        </location>
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        <location>
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            <end position="332"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="403"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56446.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW25279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="448" mass="48727" checksum="C2190563E4B5723F" modified="2016-02-17" version="1">MSGLRRALARTPPLWWSLLYFFCLLCGYYVLRPVRDAMGASADAATVFPHAWIEFARGHGWELKDFALQVLFTCTFVAMLALQPVYGALVARFPRRALLPLVYGVFIVCLFGFHWAFHAQVPGRGMAFFVWTAIFNLFAVTVFWSYMADVFDDRQARRVYGYIGAGGTAGAVLGPMLTQWLVQPLGVANLLLVSAGFLSVCVLCVVRLRPWAMARERAHGLASGEGAMGGSVWAGLRLVWQRPALRAMAITLFFSVGAATLLYNQQSAIAREFYPSAEAATRYFARIDSAVNLLAILTQLLLTRWLLNRHGVAPALLMPGLILMLGFAALMASPLPMMVAVVQVAQRASEFALSKPARETLYTRMDRPSRYKGKAVIDTAVFRGTDLAFVWVHKAVALLGTQAVFAAGALAAAGMTAGAWSIVRAQRGLPGAADPVSSVTEPNPRGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDE3</accession>
    <name>A0A0S2DDE3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glyoxalase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_23620</name>
        <name evidence="4" type="ORF">FE772_05685</name>
        <name evidence="2" type="ORF">GLE_1018</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000083">
        <property type="protein sequence ID" value="OPD61461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946464.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000083.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1018"/>
    <dbReference type="EnsemblBacteria" id="ALN56376">
        <property type="protein sequence ID" value="ALN56376"/>
        <property type="gene ID" value="GLE_1018"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61461">
        <property type="protein sequence ID" value="OPD61461"/>
        <property type="gene ID" value="BV903_23620"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1018"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1006"/>
    <dbReference type="OMA" id="LWRIGQN"/>
    <dbReference type="OrthoDB" id="1900922at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="4"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="126" mass="14347" checksum="D95CD621F9593499" modified="2016-02-17" version="1">MNLTVVEIKAFVPARDFERAKAFYLALGFELPWSSDDLAYVRHGNTSFLLQRFYVPEHAGNFMMHLLVENADDWHARVLAADVVERFGVRLEPPQDRPWGLRDFVLTDPSGVLWRIGHNLPLAAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDI6</accession>
    <name>A0A0S2DDI6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1294</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1294"/>
    <dbReference type="EnsemblBacteria" id="ALN56651">
        <property type="protein sequence ID" value="ALN56651"/>
        <property type="gene ID" value="GLE_1294"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1294"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1277"/>
    <dbReference type="OMA" id="YKAQLMP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="478"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="509" mass="55219" checksum="476BA7FB62B8A8DC" modified="2016-02-17" version="1">MDAAAETSLQDYLRADIVAADLPDLQPLLGARDLLRAFSTLFHGGEESVMVRLLVLRAIGERGQAPDWSPQELREHFAYLDPVKFDTVIGRLRDNDLLLWDVQTQRYRISPAGRQALAAIGMLLQFNREGDELAYVTAQIAAGQAVGRVRSDDLQHLLSRLNELREDFDQAVLSGSEHRIQRAAGTLQHAWRWIEKGTQIVEDISADLELDSHTHRVAQQIGRAQSAMLRQASVFQRALSQLDRHRVHLGASGLSSSDVNRYLRELDIDSLAGIADDLLTRTAIPAFMLAPIALDVAEYELVEREREAREDQSLPPAQAAPSAEGSPAAATDFGYAENWLDQLTALAGGPLADDAPLPSAALSAVVPHDNFSLSAYRLSLLGLIGDPGAENREGVSASMARLPLAWRVEPEFETIGHSGVAYMSRGRLDALSEEDLLRARQPRKRKAAAEPDGEAAAAAAAGEAAPRKRARAGKGAAANNENDDKKTASDDAAPKRRGKKAAKDTVPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDM8</accession>
    <name>A0A0S2DDM8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sulfite reductase [NADPH] flavoprotein alpha-component</fullName>
            <shortName evidence="10">SiR-FP</shortName>
            <ecNumber evidence="10">1.8.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">cysJ</name>
        <name evidence="14" type="ORF">GLE_1236</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -&gt; FAD -&gt; FMN to the hemoprotein component.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>3 H2O + hydrogen sulfide + 3 NADP(+) = 4 H(+) + 3 NADPH + sulfite</text>
            <dbReference type="Rhea" id="RHEA:13801"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="10 11">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 11">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="10 11">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Sulfur metabolism; hydrogen sulfide biosynthesis; hydrogen sulfide from sulfite (NADPH route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.2" evidence="10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1236"/>
    <dbReference type="EnsemblBacteria" id="ALN56593">
        <property type="protein sequence ID" value="ALN56593"/>
        <property type="gene ID" value="GLE_1236"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1236"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1220"/>
    <dbReference type="OMA" id="QKRYQRD"/>
    <dbReference type="UniPathway" id="UPA00140">
        <property type="reaction ID" value="UER00207"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004783">
        <property type="term" value="F:sulfite reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019344">
        <property type="term" value="P:cysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070814">
        <property type="term" value="P:hydrogen sulfide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010199">
        <property type="entry name" value="CysJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000207">
        <property type="entry name" value="SiR-FP_CysJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01931">
        <property type="entry name" value="cysJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 10 11" id="KW-0274">FAD</keyword>
    <keyword evidence="3 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 10 11" id="KW-0288">FMN</keyword>
    <keyword evidence="6 10 11" id="KW-0521">NADP</keyword>
    <keyword evidence="8 10 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="12">
        <location>
            <begin position="79"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="13">
        <location>
            <begin position="249"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="85"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="132"/>
            <end position="135"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="168"/>
            <end position="177"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="411"/>
            <end position="414"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="429"/>
            <end position="431"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="435"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="444"/>
            <end position="447"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="543"/>
            <end position="544"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="549"/>
            <end position="553"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="585"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="623"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000207-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN56593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="623" mass="67107" checksum="75357102046AD29E" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDN4</accession>
    <name>A0A0S2DDN4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_24525</name>
        <name evidence="4" type="ORF">FE772_07100</name>
        <name evidence="2" type="ORF">GLE_1327</name>
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            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000095">
        <property type="protein sequence ID" value="OPD61288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946692.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000095.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56684">
        <property type="protein sequence ID" value="ALN56684"/>
        <property type="gene ID" value="GLE_1327"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61288">
        <property type="protein sequence ID" value="OPD61288"/>
        <property type="gene ID" value="BV903_24525"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1327"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1311"/>
    <dbReference type="OrthoDB" id="2032252at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046256">
        <property type="entry name" value="DUF6289"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19806">
        <property type="entry name" value="DUF6289"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594865" evidence="1">
        <location>
            <begin position="23"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="75" mass="7815" checksum="EEB58E0063B44328" modified="2016-02-17" version="1">MRKTLALGLGLAAFAAVGAAVAAIGPTGPGQIYTYYDDNGAVVGRSSIHCDGTPEAWGKFTKNYDVGYYLCDPEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDP6</accession>
    <name>A0A0S2DDP6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1071</name>
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    <organism evidence="3 4">
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        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="gene ID" value="GLE_1071"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000061569">
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            <begin position="1"/>
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        </location>
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            <begin position="36"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="288" mass="30014" checksum="F09A495CFA2F8679" modified="2016-02-17" version="1">MGPRCARPWSRATARRRASAALGACALGLCLAAQAGPTVPAPANPAQSKMVDSKPASSNPIRDKIAQDKAVQGGATQARPTQAASPQNASAQSGAVRGASVQNPPTQAGSKPNASAAAGPVPSGPILARPPALRDDKMATRDWIGRVVPPYPDGYRSNTGGCVGSGRSAEQICARSIGTIDDNEDRSQLLYAAELIGRAGNEARWKITDVVAYPRLQRGERVSISTCLFDGAGDPGVIAVVDTLVENAAARETFDAVRWAVRLDRSKGRFVEIKAAEVQCYNEGAEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDQ1</accession>
    <name>A0A0S2DDQ1_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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        <lineage>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1306"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1290"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="40" mass="4589" checksum="F1C66C8332B6197E" modified="2016-02-17" version="1">MPSVRRAVAVAGWAMRELRLRQDEHDATTPRHSGESRNPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDW0</accession>
    <name>A0A0S2DDW0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Recombinase family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Site-specific recombinase, integrase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_07645</name>
        <name evidence="3" type="ORF">GLE_1454</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
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    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW25554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1454"/>
    <dbReference type="EnsemblBacteria" id="ALN56811">
        <property type="protein sequence ID" value="ALN56811"/>
        <property type="gene ID" value="GLE_1454"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1454"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1434"/>
    <dbReference type="OMA" id="HQKYSTE"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038109">
        <property type="entry name" value="DNA_bind_recomb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011109">
        <property type="entry name" value="DNA_bind_recombinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036162">
        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07508">
        <property type="entry name" value="Recombinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00239">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00857">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53041">
        <property type="entry name" value="SSF53041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51737">
        <property type="entry name" value="RECOMBINASE_DNA_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51736">
        <property type="entry name" value="RECOMBINASES_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Resolvase/invertase-type recombinase catalytic" evidence="1">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Recombinase" evidence="2">
        <location>
            <begin position="174"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="497" mass="55741" checksum="DC83583DCBEDA4F1" modified="2016-02-17" version="1">MSTDHQRYSTENQSDAIHAYAAAHGMRIIRTYRDDGKSGLDIGGREALKQLLEDVRSGRAEFKAILVYDVSRWGRFQNADESAAYEYECSKAGIKVIYCAEPFENDGSPLSTIYKSIKRSMAGEYSRELSAKVFAGQCRLVRLGFHQGGLAGFGLRRALLDEQRNLKGELSRGEHKSIQTDRVVLVPGPAWEVALVERIYREFVLQGSTERHIADRLNEEGKSTDLDRPWSRATVHQVLTNEKYIGNNVYNRTSSKLKQAAVRNPPERWVRCDGAFEGIISLDLFTQARQIIASRSQRLSDAQMLELLIDLWRRAGTLSGLVIDESEDMPSSTSYQSRFGGLLRAYALVGYTPDRDYRYLEVNRALRAWRPDIVGQVMQAIQAVGAHVEQDAGNDLLHVNGEWTASIILAKCEVSAGGRLRWSLRFDTSLAPDITCAVRMGVSNAQPMDHYLIPRLDMGAWPQRLGEENGGVIDGYRFDTFQSLAELAARTPLEKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDW4</accession>
    <name>A0A0S2DDW4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Propionate--CoA ligase</fullName>
            <ecNumber evidence="4">6.2.1.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">prpE</name>
        <name evidence="5" type="ORF">FE772_06920</name>
        <name evidence="4" type="ORF">GLE_1286</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="6.2.1.17" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW25436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN56643">
        <property type="protein sequence ID" value="ALN56643"/>
        <property type="gene ID" value="GLE_1286"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1286"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1269"/>
    <dbReference type="OMA" id="YSSLDWA"/>
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    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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        <property type="term" value="P:propionate catabolic process, 2-methylcitrate cycle"/>
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        <property type="project" value="InterPro"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="3"/>
            <end position="57"/>
        </location>
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    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
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            <end position="501"/>
        </location>
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        <location>
            <begin position="510"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="631" mass="68994" checksum="5A087A5C8F95F066" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDY7</accession>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">C3</strain>
        </source>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Fur family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN56706">
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        <property type="gene ID" value="GLE_1349"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    </dbReference>
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    </dbReference>
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        <source>
            <dbReference type="ARBA" id="ARBA00007957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="165" mass="17975" checksum="378C99301A172876" modified="2016-02-17" version="1">MNADTACTDPHHHVHDGDAFVHEVERACEQRGLRLTPIRAHALRLIADAGRPMKAYDLLDQMKATHDAAAPPTIYRALDFLLEHGFIHKLASINAFVGCHHPGGAQHAVPFLICDTCQSATELEDERIVDLLEARARALGFVPQAQTLEVHGMCADCVTAKAAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-06-17" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDZ6</accession>
    <name>A0A0S2DDZ6_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1502</name>
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    <organism evidence="3 4">
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        <lineage>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="201" mass="22279" checksum="F1A3A4B2BA7A9AC3" modified="2016-02-17" version="1">MTQDRIAPDRIAPDGAATAPAPVAGDAQALDARERDFLRAKQSSEAPRVLWSCVALGVVCFVPAIVFDPDFRNVWAIAGISAAIGFMALLAWSESLDQSNLRDDLAAGIKLWREGVLTGVMERDDGESWPPIYCLYIALDGDDPELPTRFSVPWHCYEAVRTDRRVRIAYAPKALRLLNLIDGDYQYVAVLRQFDEHPPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE29</accession>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">GLE_1534</name>
    </gene>
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        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56891">
        <property type="protein sequence ID" value="ALN56891"/>
        <property type="gene ID" value="GLE_1534"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1534"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1516"/>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
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        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="114" mass="12236" checksum="DD42D7AAE2618897" modified="2016-02-17" version="1">MDAVREGYRSDAAHALHARPDGAGAPAWTQGPGEVAWPRPRARDASRLDRLYRLKLAGRDPERRRRRRRSLHELACWFALALLLAAALASPVRAAGPAAPDAATTPAAAPRTAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE39</accession>
    <name>A0A0S2DE39_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-hairpin-helix domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Pathogenicity locus</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_21660</name>
        <name evidence="3" type="ORF">FE772_07805</name>
        <name evidence="1" type="ORF">GLE_1487</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000072">
        <property type="protein sequence ID" value="OPD61785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946815.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000072.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56844">
        <property type="protein sequence ID" value="ALN56844"/>
        <property type="gene ID" value="GLE_1487"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61785">
        <property type="protein sequence ID" value="OPD61785"/>
        <property type="gene ID" value="BV903_21660"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1487"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1468"/>
    <dbReference type="OMA" id="SSCWKNS"/>
    <dbReference type="OrthoDB" id="2062176at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD61785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="85" mass="8794" checksum="68D383012D1297B0" modified="2016-02-17" version="1">MAFSESERQRLLALKGVGETVIARLEQAGYGSLNALAGADPARICADVAGMLRASCWGNSPQARAAISAIVGLARSSTLPTSHPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE59</accession>
    <name>A0A0S2DE59_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_07405</name>
        <name evidence="1" type="ORF">GLE_1398</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946747.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56755">
        <property type="protein sequence ID" value="ALN56755"/>
        <property type="gene ID" value="GLE_1398"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1398"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1380"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="108" mass="11323" checksum="A531D7BE12EAEBF1" modified="2016-02-17" version="1">MTPVGAQGLGSAGPAKLTDGYILSFATLRGLSGAIDIGVEEAPCFSPERAAALVGGATGSVEFDAHMIDHGKTYTIEKNGFYVSFATTDETYRCVKAIHLWPSDKKAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEJ7</accession>
    <name>A0A0S2DEJ7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SPFH domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Spfh domain/band 7 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_08265</name>
        <name evidence="3" type="ORF">GLE_1588</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW25664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946901.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56945">
        <property type="protein sequence ID" value="ALN56945"/>
        <property type="gene ID" value="GLE_1588"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1588"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1568"/>
    <dbReference type="OMA" id="NLMVVLC"/>
    <dbReference type="OrthoDB" id="1213601at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="2">
        <location>
            <begin position="59"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="290" mass="31354" checksum="2F875F4706868CBA" modified="2016-02-17" version="1">MKENPIQSLPGIPALLVLLLVLLGCGYGFIATVTGPDSPVTVGALAFIALAVLALVCLAGLYMVEPNQAAVLSLFGKYVGTVKDNGLRWNNPLYAKRKVSQRVRNFESGKLKVNELDGSPIEIAAVIVWQVVDSAEAVYNVDDYETFVHIQSESALRAMATSYPYDQHEDGQLSLRSHASEISLHLKQELQERLADAGVDIIDARISHLAYAAEIAQAMLQRQQANAVIAARTRIVAGAVGMVEMALAELQKNGVVQLDEERKAQMVSNLLVVLCGERGTQPIVNTGSLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEM5</accession>
    <name>A0A0S2DEM5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MoaD/ThiS family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Molybdopterin converting factor, subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">moaD</name>
        <name evidence="2" type="ORF">FE772_08655</name>
        <name evidence="1" type="ORF">GLE_1671</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946964.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1671"/>
    <dbReference type="EnsemblBacteria" id="ALN57028">
        <property type="protein sequence ID" value="ALN57028"/>
        <property type="gene ID" value="GLE_1671"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1671"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1650"/>
    <dbReference type="OMA" id="KHRFSRP"/>
    <dbReference type="OrthoDB" id="1995573at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="80" mass="8504" checksum="EBAF78FFC89D2DC6" modified="2016-02-17" version="1">MSTLTVLYFASLRDAAGIASESVPADARDLRGLYETLRARHGFALPVERLRVAVDGAFAQWDDAPRAGSEVAFIPPVSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DES1</accession>
    <name>A0A0S2DES1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1794</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947052.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1794"/>
    <dbReference type="EnsemblBacteria" id="ALN57147">
        <property type="protein sequence ID" value="ALN57147"/>
        <property type="gene ID" value="GLE_1794"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1794"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1766"/>
    <dbReference type="OMA" id="IEITIAY"/>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="302" mass="32959" checksum="333F21D7128E677B" modified="2016-02-17" version="1">MDSLALMRSFRRVVELGSFARAADDLALSAAGLSKQVRQLEARLGTVLLQRTTRRMSLTDGGRLYYAECCRLLDEIDALEQRMRAGSERVDGLLRINAPLSFGLCVLSPLLSRFLAAHPHLRLDLALDDRVVDLVGEGFDVAVRLRSELEDSSLVARRLGQVEQLLCAAPSYLQRHGQPRTPQELCGHALLGYSLSQSPRAWQLQGADGASEFTLPAPRVAANNSLLLRDLLVDGHGVGSLPAFVAAPAIAADRLRELLPRHRQPPRHVHAVYATGRLLPAKVRAFVDFLGDELPAALAADC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DET7</accession>
    <name>A0A0S2DET7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Isocitrate dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.41</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Isocitrate/isopropylmalate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_07080</name>
        <name evidence="4" type="ORF">FE772_08570</name>
        <name evidence="2" type="ORF">GLE_1654</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.41" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000013">
        <property type="protein sequence ID" value="OPD64647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946949.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1654"/>
    <dbReference type="EnsemblBacteria" id="ALN57011">
        <property type="protein sequence ID" value="ALN57011"/>
        <property type="gene ID" value="GLE_1654"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64647">
        <property type="protein sequence ID" value="OPD64647"/>
        <property type="gene ID" value="BV903_07080"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1654"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1633"/>
    <dbReference type="OMA" id="TCAHKAN"/>
    <dbReference type="OrthoDB" id="1551125at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004449">
        <property type="term" value="F:isocitrate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iso_dh" evidence="1">
        <location>
            <begin position="4"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="337" mass="35973" checksum="735E8A933CDA06AD" modified="2016-02-17" version="1">MTQTITVIRGDGIGPEIMDATLHVLDAMNVGLSYEFADAGLVALEKHGELLPAATMDSIRKNRIALKSPLTTPVGEGFSSINVELRKRFDLYANVRPAKSFPNTKSRFPSGVDLITVRENTEGAYIGEGQTLSEDGETAMLTQKITRRGSERIVRYAFDLARKTGRKKVTVVHKANILKSTSGLFLKTAREVAQQYPDIQCNEMIVDNTCMQLVMRPEQFDIIVTTNLFGDIISDLCAGLVGGLGLAPGANIGTDAAIFEAVHGSAPDIAGKGIANPCALLLGAAQMLDHLGQPDKATKLREAIIATLEAKDSLTPDLGGDGNTMSFAKAIASRATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF35</accession>
    <name>A0A0S2DF35_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">Acetylglutamate kinase</fullName>
            <ecNumber evidence="3 7">2.7.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">argB</name>
        <name evidence="11" type="ORF">GLE_1839</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamyl 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14629"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57936"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.2.8" evidence="3 7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947085.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1839"/>
    <dbReference type="EnsemblBacteria" id="ALN57191">
        <property type="protein sequence ID" value="ALN57191"/>
        <property type="gene ID" value="GLE_1839"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1839"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1810"/>
    <dbReference type="OMA" id="EGLYEDW"/>
    <dbReference type="OrthoDB" id="901370at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00107"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003991">
        <property type="term" value="F:acetylglutamate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04252">
        <property type="entry name" value="AAK_NAGK-fArgBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004662">
        <property type="entry name" value="AcgluKinase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011242">
        <property type="entry name" value="ArgB_GNAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041734">
        <property type="entry name" value="NAGK-fArgBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006855">
        <property type="entry name" value="Vertebrate-like_GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04768">
        <property type="entry name" value="NAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036441">
        <property type="entry name" value="NAGK_DUF619"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00761">
        <property type="entry name" value="argB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51731">
        <property type="entry name" value="GNAT_NAGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="10">
        <location>
            <begin position="295"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="80"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="9">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="9">
        <location>
            <position position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR036441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR036441-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR036441-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN57191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="442" mass="48671" checksum="007A127689E1820E" modified="2016-02-17" version="1">MSVSMDNHLQTRQTIVRLLSSMASAKEISQYLKRFSQLDSKRFAVVKVGGAVLRDDLAALTSSLAFLQDVGLTPIVIHGAGPQLDEELSAAGIVKQTVGGLRVTSPEALAIVRRVFQSQNLKLVEALQSGDGRATSIISGVFEAEFLDRDTYGLVGEVKKVNLAPIEASLQAGSIPVIASLGETPGGQILNINADFAANELVQVLQPYKIVFLTGTGGLLDDNGRVIDSINLSTEYEHLIQQPWINGGMKVKIEQIKDLLDKLPLTSSVSITKPSELAKELFTHKGSGTLVRRGERVLQASRWDELDLTRLRGLIDSAFGRKLVDGYFENTQLKQAYVSENYRAAIVLIEAEGRTYLDKFAVLDDAQGEGLGRAVWQVMREQNPSVFWRSRHGNAVNPFYYSESDGCLKQEKWKVFWYGMDGFDEIAACVEYAGRRTPTLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFD3</accession>
    <name>A0A0S2DFD3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1922</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57273">
        <property type="protein sequence ID" value="ALN57273"/>
        <property type="gene ID" value="GLE_1922"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1922"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1888"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="60" mass="6446" checksum="B38D92380A1E06AD" modified="2016-02-17" version="1">MIGGGARPPAQRAGGRAHDAGRRAARRRGALRTRSADAARGVADERWRSRAAALLRCRQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFD6</accession>
    <name>A0A0S2DFD6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_10160</name>
        <name evidence="2" type="ORF">GLE_2000</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947200.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57350">
        <property type="protein sequence ID" value="ALN57350"/>
        <property type="gene ID" value="GLE_2000"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2000"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1967"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726800" evidence="1">
        <location>
            <begin position="21"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="81" mass="8442" checksum="D2840FF6791B06B5" modified="2016-02-17" version="1">MKFKFHAVALTLLLPIAATAATITVSGHGQSYDPGIAMADARADAAGKCAAQGGTPVKEVYSHVTRANLWLADSIWSCEVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFL5</accession>
    <name>A0A0S2DFL5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1931</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57282">
        <property type="protein sequence ID" value="ALN57282"/>
        <property type="gene ID" value="GLE_1931"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1931"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1897"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="84" mass="8802" checksum="B97D675A2840DFAF" modified="2016-02-17" version="1">MGVARKPPRLARGAKFLAESSSNRFRRGFPARTRAIAACAQVLSPCAQASPASAPPQSGAPPGLFALRSDLPRLRASPYGLRAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFZ2</accession>
    <name>A0A0S2DFZ2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Elongation factor P-like protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Elongation factor P-like protein YeiP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">yeiP</name>
        <name evidence="5" type="ORF">BV903_17405</name>
        <name evidence="6" type="ORF">FE772_09810</name>
        <name evidence="4" type="ORF">GLE_1927</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">C3</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the elongation factor P family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000046">
        <property type="protein sequence ID" value="OPD62707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947148.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000046.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1927"/>
    <dbReference type="EnsemblBacteria" id="ALN57278">
        <property type="protein sequence ID" value="ALN57278"/>
        <property type="gene ID" value="GLE_1927"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62707">
        <property type="protein sequence ID" value="OPD62707"/>
        <property type="gene ID" value="BV903_17405"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1927"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1893"/>
    <dbReference type="OMA" id="LYRMRMY"/>
    <dbReference type="OrthoDB" id="1260763at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05794">
        <property type="entry name" value="S1_EF-P_repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015365">
        <property type="entry name" value="Elong-fact-P_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020599">
        <property type="entry name" value="Transl_elong_fac_P/YeiP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013185">
        <property type="entry name" value="Transl_elong_KOW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001059">
        <property type="entry name" value="Transl_elong_P/YeiP_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013852">
        <property type="entry name" value="Transl_elong_P/YeiP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30053">
        <property type="entry name" value="PTHR30053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01132">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08207">
        <property type="entry name" value="EFP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09285">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005901">
        <property type="entry name" value="EF-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01185">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00841">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01275">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EFP" evidence="3">
        <location>
            <begin position="68"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Elong-fact-P_C" evidence="2">
        <location>
            <begin position="131"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD62707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW25915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="188" mass="20436" checksum="D978A62EBEFD1E7A" modified="2016-02-17" version="1">MKAYDVKKGNVIEHNGTVYQVRDIERSSPQGRGGNVKFRFTMYSVPGGTKFDLSAGAEDELKEVELSRRQATYSYKDGDAFVFLDDEDYTPYTLDADVVGDAAGYIIADLGGFYVQIIDDLPVGLQLPASVSLEVIETPPELKGGTATKRPKPAKLETGIEIMVPEYIGTGERVLVNTATGEFAGRAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG02</accession>
    <name>A0A0S2DG02_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">Phosphoglucosamine mutase</fullName>
            <ecNumber evidence="6 8">5.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 13" type="primary">glmM</name>
        <name evidence="14" type="ORF">FE772_10855</name>
        <name evidence="13" type="ORF">GLE_2150</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">C3</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23424"/>
            <dbReference type="ChEBI" id="CHEBI:58516"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="EC" id="5.4.2.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="PTM">
        <text evidence="6">Activated by phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.10" evidence="6 8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947319.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2150"/>
    <dbReference type="EnsemblBacteria" id="ALN57500">
        <property type="protein sequence ID" value="ALN57500"/>
        <property type="gene ID" value="GLE_2150"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2150"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2114"/>
    <dbReference type="OMA" id="PHNPEPL"/>
    <dbReference type="OrthoDB" id="1265792at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008966">
        <property type="term" value="F:phosphoglucosamine mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05802">
        <property type="entry name" value="GlmM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01554_B">
        <property type="entry name" value="GlmM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006352">
        <property type="entry name" value="GlmM_bact"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01455">
        <property type="entry name" value="glmM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 6 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="10">
        <location>
            <begin position="3"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="11">
        <location>
            <begin position="159"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="12">
        <location>
            <begin position="259"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="9">
        <location>
            <begin position="375"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="6">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="binding site" description="via phosphate group" evidence="6">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="Phosphoserine" evidence="6">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN57500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW26096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="446" mass="47518" checksum="E487BE4E0A5E25DD" modified="2016-02-17" version="1">MTRKYFGTDGIRGRVGEGAISADFVLRLGNAYGHALQRRDWRNPMVIIGKDTRISNYMFEAALEAGLVAAGVDVQLMGPMPTPAVAHLTRSLRADGGIVISASHNPHYDNGIKFFSADGEKLDDDTELAIEAALEQPFRTVESERLGRAVRTRDAIGRYLEACKGSVSRGFDLSGLRIALDCANGATYQVGPLVLRELGARVDAIGVDPSGLNINDGVGSTHPQTLVAKVQSSGADLGIAFDGDGDRVMFVDSEGRICDGDDLLYILATDWQDSGRLRGPVVGTLMTNYGLERALEQRGIGFIRAKVGDRYVHQQLIAHGGMLGGEASGHLLCLDRTSTGDGIVSALQVLEVLARRKLSLREALAGLQRVPQKTVNVRFEGASKPTEAASVKEALKLAEAAVAGRGRAFLRPSGTEPVVRVTVEADDAKLMQDTLDALSAAVKAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG20</accession>
    <name>A0A0S2DG20_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADP-specific glutamate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">D9T17_12450</name>
        <name evidence="11" type="ORF">FE772_10045</name>
        <name evidence="10" type="ORF">GLE_1976</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">OH11</strain>
        </source>
    </reference>
    <reference evidence="11 15" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:11612"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.4.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000031">
        <property type="protein sequence ID" value="ROU06658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947183.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1976"/>
    <dbReference type="EnsemblBacteria" id="ALN57326">
        <property type="protein sequence ID" value="ALN57326"/>
        <property type="gene ID" value="GLE_1976"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1976"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1941"/>
    <dbReference type="OMA" id="TYVADMD"/>
    <dbReference type="OrthoDB" id="1184827at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016639">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033524">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016211">
        <property type="entry name" value="Glu/Phe/Leu/Val_DH_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42722">
        <property type="entry name" value="PTHR42722"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000188">
        <property type="entry name" value="Phe_leu_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00074">
        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELFV_dehydrog" evidence="9">
        <location>
            <begin position="143"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="6">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="179"/>
            <end position="184"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000188-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000188-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN57326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW25956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROU06658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="367" mass="39846" checksum="814CC8C3D3D2B596" modified="2016-02-17" version="1">MIFETLDTFGHEQVVFCHNKDAGLKAIIAIHNTVLGPALGGLRMWPYKTEQDALNDVLRLSRGMTYKNAVAGLNIGGGKAVIIGDPSADKSEALFRAFGKFVDSLGGRYITAEDVGIDVNDMEYVYRETEYVTGVHQVHGGSGDPSPFTAYGTLQGLMAALNKRFGDEEVGKYSYAVQGLGHVGMEFVKLLKERGAKIFVTDINKGLVDKAVSEYGAEAVGLDEIYDVNADVYSPCALGGTVNEQTLPRLKAKIICGAANNQLANNAIGDEVAKRGILYAPDYAVNAGGVMNVALELDGYNRERAMRMMRTIYHNLGRIFEIAERDSIPTYTAADRLAEERISAIGKLKLPLGRSNPSFRGRIRSGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG45</accession>
    <name>A0A0S2DG45_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_2182</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2182"/>
    <dbReference type="EnsemblBacteria" id="ALN57531">
        <property type="protein sequence ID" value="ALN57531"/>
        <property type="gene ID" value="GLE_2182"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2182"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2144"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045474">
        <property type="entry name" value="GEVED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045826">
        <property type="entry name" value="SpaA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01345">
        <property type="entry name" value="DUF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20009">
        <property type="entry name" value="GEVED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19403">
        <property type="entry name" value="SpaA_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GEVED" evidence="4">
        <location>
            <begin position="58"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="SpaA_2" evidence="3">
        <location>
            <begin position="243"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="SpaA_2" evidence="3">
        <location>
            <begin position="351"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="SpaA_2" evidence="3">
        <location>
            <begin position="451"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="domain" description="SpaA_2" evidence="3">
        <location>
            <begin position="551"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="SpaA_2" evidence="3">
        <location>
            <begin position="649"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="domain" description="SpaA_2" evidence="3">
        <location>
            <begin position="744"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="domain" description="DUF11" evidence="2">
        <location>
            <begin position="869"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="954" mass="92717" checksum="CCB9ED7A0F73DCAB" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG53</accession>
    <name>A0A0S2DG53_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2215</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57564">
        <property type="protein sequence ID" value="ALN57564"/>
        <property type="gene ID" value="GLE_2215"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2215"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2177"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="72" mass="7823" checksum="AE1A31833981AEF7" modified="2016-02-17" version="1">MRADALGDGRPACLLRARESCVCQDCACEGCVREGCAGADRIGEDRACKARVRERRAGDAGVWLRADRVGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGA3</accession>
    <name>A0A0S2DGA3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Polyribonucleotide nucleotidyltransferase</fullName>
            <ecNumber evidence="7">2.7.7.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Polynucleotide phosphorylase</fullName>
            <shortName evidence="7">PNPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">pnp</name>
        <name evidence="10" type="ORF">BV903_08710</name>
        <name evidence="11" type="ORF">FE772_11000</name>
        <name evidence="9" type="ORF">GLE_2180</name>
    </gene>
    <organism evidence="9 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">C3</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n)</text>
            <dbReference type="Rhea" id="RHEA:22096"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the polyribonucleotide nucleotidyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.8" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000018">
        <property type="protein sequence ID" value="OPD64372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947343.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2180"/>
    <dbReference type="EnsemblBacteria" id="ALN57529">
        <property type="protein sequence ID" value="ALN57529"/>
        <property type="gene ID" value="GLE_2180"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64372">
        <property type="protein sequence ID" value="OPD64372"/>
        <property type="gene ID" value="BV903_08710"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2180"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2142"/>
    <dbReference type="OMA" id="LHILDVM"/>
    <dbReference type="OrthoDB" id="122725at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004654">
        <property type="term" value="F:polyribonucleotide nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01595">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012162">
        <property type="entry name" value="PNPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015848">
        <property type="entry name" value="PNPase_PH_RNA-bd_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036456">
        <property type="entry name" value="PNPase_PH_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11252">
        <property type="entry name" value="PTHR11252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03726">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005499">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46915">
        <property type="entry name" value="SSF46915"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="SSF54791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="SSF55666"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03591">
        <property type="entry name" value="polynuc_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S1 motif" evidence="8">
        <location>
            <begin position="623"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="487"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="493"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN57529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD64372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW26120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="702" mass="75322" checksum="9A2973AB982B2798" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGB1</accession>
    <name>A0A0S2DGB1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2384 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2213</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947368.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2213"/>
    <dbReference type="EnsemblBacteria" id="ALN57562">
        <property type="protein sequence ID" value="ALN57562"/>
        <property type="gene ID" value="GLE_2213"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2213"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2175"/>
    <dbReference type="OMA" id="RMQSGAY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024467">
        <property type="entry name" value="Xre/MbcA/ParS-like_toxin-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09722">
        <property type="entry name" value="DUF2384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2384" evidence="2">
        <location>
            <begin position="156"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="213" mass="22135" checksum="1ACF545BCF2E9044" modified="2016-02-17" version="1">MSKPAKPPTPAKGAAEASAKPAKAAPSRGRREAARSVRDAAAYPLPTSKRSLSVKEPLAAEAYGAPATLNGYVAYLRTATPLQRVEAEREGVPARMVKHMASDMDLPAVRMFDILGIAKATAEAKAAQQARITGASGQAALGLIHLLGIARDIVDDSTDPAAPDFDAARWLGHWIEQPQAALGGQRPADLLDTPTGLSVVARLLGALASGAYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGE4</accession>
    <name>A0A0S2DGE4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative glutamate--cysteine ligase 2</fullName>
            <ecNumber evidence="2">6.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Gamma-glutamylcysteine synthetase 2</fullName>
            <shortName evidence="2">GCS 2</shortName>
            <shortName evidence="2">Gamma-GCS 2</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_2066</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>ATP + L-cysteine + L-glutamate = ADP + gamma-L-glutamyl-L-cysteine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13285"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.2" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2066"/>
    <dbReference type="EnsemblBacteria" id="ALN57416">
        <property type="protein sequence ID" value="ALN57416"/>
        <property type="gene ID" value="GLE_2066"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2066"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2031"/>
    <dbReference type="OMA" id="LIFGLHV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004357">
        <property type="term" value="F:glutamate-cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042398">
        <property type="term" value="P:cellular modified amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01609">
        <property type="entry name" value="Glu_cys_ligase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006336">
        <property type="entry name" value="GCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011793">
        <property type="entry name" value="YbdK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04107">
        <property type="entry name" value="GCS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02050">
        <property type="entry name" value="gshA_cyan_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="376"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="380"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="395" mass="43926" checksum="CDE53B25C31A73EB" modified="2016-02-17" version="1">MSAQCDYSFGIEEEFFLVRPHSRLLATQVPARLLKRARAELGECIESELLQAQIEIASPVQCDIGQARRQLGELRRGLAELAHEHGLALLAAGTHPLGQWREQSPTDKPRYRQLVEDFQIVARRSQVCGLHVHVQLPDGVDRVQAMNRAMPWLPLLLALSTSSPFWDRLNSGLMSYRQAMYDEWPRTGIPDFFAGEAEYDAFADLLKRAGAIADAGSLWWAIRPSPNFPTVELRIADACTHLDDSLAIAALFRCLMRHIARRRAEPPPCDAATRRLIDENRWRAKRSGLQAEFIDARGGSEPALEQLRRLRELVAEDAVALDCTQALRRLDTIAERGTSAHTQLAIYREHRQRGASRNGALKAVVDWLLHATVPAAADAAPTPSAPPTPSAPDSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGM4</accession>
    <name>A0A0S2DGM4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_11080</name>
        <name evidence="2" type="ORF">GLE_2200</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57549">
        <property type="protein sequence ID" value="ALN57549"/>
        <property type="gene ID" value="GLE_2200"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2200"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2162"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726804" evidence="1">
        <location>
            <begin position="34"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="142" mass="14573" checksum="91EE3246D3EB2C99" modified="2016-02-17" version="1">MKSIGSTLAHAALTGALALAAIGSFAVPATAQAQPGSNPLLWCFVGPNDQPGNGPFGRCTSFYPSSSYRADFEVRNLPAGTYSYVWTNDLGMVLPCTTNRCYVTYQSGAGGGVIDTVSVTYTNLATGVATTLGRTVAIGGPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH11</accession>
    <name>A0A0S2DH11_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Twin-arginine translocation pathway signal protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947496.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2381"/>
    <dbReference type="EnsemblBacteria" id="ALN57730">
        <property type="protein sequence ID" value="ALN57730"/>
        <property type="gene ID" value="GLE_2381"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2381"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2342"/>
    <dbReference type="OMA" id="DHEVRNN"/>
    <dbReference type="OrthoDB" id="165142at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09423">
        <property type="entry name" value="PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoD" evidence="1">
        <location>
            <begin position="157"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="532" mass="58463" checksum="B37D27187ABDD296" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHR8</accession>
    <name>A0A0S2DHR8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cytokinin riboside 5'-monophosphate phosphoribohydrolase</fullName>
            <ecNumber evidence="2">3.2.2.n1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_19830</name>
        <name evidence="5" type="ORF">FE772_13645</name>
        <name evidence="3" type="ORF">GLE_2726</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AMP + H2O = adenine + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:20129"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.2.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LOG family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.n1" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000058">
        <property type="protein sequence ID" value="OPD62184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947769.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000058.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2726"/>
    <dbReference type="EnsemblBacteria" id="ALN58074">
        <property type="protein sequence ID" value="ALN58074"/>
        <property type="gene ID" value="GLE_2726"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62184">
        <property type="protein sequence ID" value="OPD62184"/>
        <property type="gene ID" value="BV903_19830"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2726"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2684"/>
    <dbReference type="OMA" id="HQKPIGL"/>
    <dbReference type="OrthoDB" id="1255127at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008714">
        <property type="term" value="F:AMP nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009691">
        <property type="term" value="P:cytokinin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005269">
        <property type="entry name" value="LOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00730">
        <property type="entry name" value="TIGR00730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0203">Cytokinin biosynthesis</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD62184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="197" mass="21858" checksum="4B986BC5BB36D0C2" modified="2016-02-17" version="1">MKTLCVYCGSNAGSKPIYTERAMALGNRLARDGVALVYGGGNVGLMGVVADAVLEAGGEAIGVIPEQLVNWEVAHRGLSKLEIVGSMHERKQRMFDLADGFVALPGGFGTLDEMFEMLTWRQLGIGDKPCAFLDIDGFYSPLMGMLDRMVEERFLHADQRRDLWHGDDLDAMLAWMRAYEPAQASKWMDEKRRGALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHY0</accession>
    <name>A0A0S2DHY0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Molybdopterin molybdenumtransferase</fullName>
            <ecNumber evidence="7">2.10.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FE772_14480</name>
        <name evidence="9" type="ORF">GLE_2903</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenylyl-molybdopterin + H(+) + molybdate = AMP + H2O + Mo-molybdopterin</text>
            <dbReference type="Rhea" id="RHEA:35047"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
            <dbReference type="ChEBI" id="CHEBI:62727"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.10.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the MoeA family.</text>
    </comment>
    <dbReference type="EC" id="2.10.1.1" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947895.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2903"/>
    <dbReference type="EnsemblBacteria" id="ALN58251">
        <property type="protein sequence ID" value="ALN58251"/>
        <property type="gene ID" value="GLE_2903"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2903"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2865"/>
    <dbReference type="OMA" id="MTGAMVP"/>
    <dbReference type="OrthoDB" id="651103at2"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061599">
        <property type="term" value="F:molybdopterin molybdotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032324">
        <property type="term" value="P:molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00887">
        <property type="entry name" value="MoeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038987">
        <property type="entry name" value="MoeA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005111">
        <property type="entry name" value="MoeA_C_domain_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036688">
        <property type="entry name" value="MoeA_C_domain_IV_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005110">
        <property type="entry name" value="MoeA_linker/N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036135">
        <property type="entry name" value="MoeA_linker/N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10192">
        <property type="entry name" value="PTHR10192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03454">
        <property type="entry name" value="MoeA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03453">
        <property type="entry name" value="MoeA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63867">
        <property type="entry name" value="SSF63867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63882">
        <property type="entry name" value="SSF63882"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="6 7" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="8">
        <location>
            <begin position="182"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN58251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW26678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="406" mass="43610" checksum="6B56BF6B81E325AD" modified="2016-02-17" version="1">MTDFPTGLLFDEAMAVTAEVAAAHRLEIEHPALSRCHGRVLAQDVVAPLSLPPFDNSAMDGFALRHADLSGEQTELRLVGEQFAGLALGLALGAGECARITTGAPLPAGADTVAIKENVRVDGDRVWVPQAKRGHHVRYAGEDVAEGETVLRAGQALTPARVSLAASLGLSSLPVRRKPTVAVFTSGDELVEPGMPLRPGQIYDSNRELLMGLLRADGLEPTAWPRLPDDPRQVEIALRDAACAFDLVFTCGAVSAGEKDHIPAVLGQFGRIHFWKVKMRPGMPLLLASMDQARCLGLPGNPVSVLATYLSFGRALIDGLQGRVEPRPKLRARLVGGIEKSHPRREFVRARLRSDEDGVLWVDPNPATASHRLRAAADSDALMVVAEGEQRLQEGAVMEVWPYALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI29</accession>
    <name>A0A0S2DI29_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2697</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58045">
        <property type="protein sequence ID" value="ALN58045"/>
        <property type="gene ID" value="GLE_2697"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2697"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2656"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595218" evidence="2">
        <location>
            <begin position="42"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="297" mass="31067" checksum="8DC0CDC0651D755F" modified="2016-02-17" version="1">MAAPPHSRRTHSQDKDDYRMRSTSKTGLALAGLLLSANALACDTILPANQIGISAPGKYCLSGNRSLPIEINGTDIELDCRTRTLVNPSTGGGPGGGVGIMVRGGGKVVVRNCRVDGFANGIQADVGSGAQLLNNTVLRAQDTPIIIHGNPFGPPDPQAEPARIVGNRVIGYGGDQANWGPALRVHGLPRAVIANNVVAGYRGRGGLELGESPDAQLTGNQFLDFEAGHRMIQFINSPRARVVHNTIMSRQPIGEGLTGAVDATCVENVFINVQPSGFAGCSVARYNVEQPQPPTGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI77</accession>
    <name>A0A0S2DI77_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">VirB6 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">virB6</name>
        <name evidence="7" type="ORF">GLE_2812</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2812"/>
    <dbReference type="EnsemblBacteria" id="ALN58160">
        <property type="protein sequence ID" value="ALN58160"/>
        <property type="gene ID" value="GLE_2812"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2812"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2769"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030255">
        <property type="term" value="P:protein secretion by the type IV secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007688">
        <property type="entry name" value="Conjugal_tfr_TrbL/VirB6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04610">
        <property type="entry name" value="TrbL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="327"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="352" mass="37358" checksum="18A044A753AAE6EC" modified="2016-02-17" version="1">MVSFGASSLMDWMQAADLPNMAFFALIKDHLDTMILQFQGRLLNRVGKIIGAFAATVVTLWILVQGFRIATGQSREPMMALVVNSLKSVLIVGIALSAAVTADKSYDALTDGLSKVVREVMTGRTDDGPYADMDKVLGVLQVGIELVNSIDVGGDVMTNDTKQKSMTMIGVGLGGPVIMAMIAMMLNKIAMALFIGLGPFFILCLLFDQTKALFQRWLYYGIATMLSMAVLITMTTIAIDLILAVGAAFWVPSMIPGLGTNKESLMSMALQQGGLGTILSALILTAPPMAGAFFNGVLGQLGGSNFFQGGEFRGGSHQTTNTFTPGQPGYVPQQANHSRPVGEAAAKMGPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIA9</accession>
    <name>A0A0S2DIA9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidoglycan-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Putative peptidoglycan binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_13920</name>
        <name evidence="3" type="ORF">GLE_2788</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947813.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2788"/>
    <dbReference type="EnsemblBacteria" id="ALN58136">
        <property type="protein sequence ID" value="ALN58136"/>
        <property type="gene ID" value="GLE_2788"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2788"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2744"/>
    <dbReference type="OMA" id="HDANAGP"/>
    <dbReference type="OrthoDB" id="624267at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PG_binding_1" evidence="2">
        <location>
            <begin position="247"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="405"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="448" mass="48892" checksum="041DDD5E77FB5909" modified="2016-02-17" version="1">MPNYKIVESVGSKVQNVHDFEDIDRHHPSRGNEKGRVYGTVNGEREELLGNYNGRATVTRDGDHFVSKDFVLQAGGSASVKVPAVANGYIGKIDPANGIVQIYDKPANDPSREMIAQYRHLDLRNTNLREGQKIEYGESVGIQGGFNKGNPNAFGKHVHLDINTSYLPQADRYIRDMDSGAITTDKRPPHSENLTGNAKVSDVSGKGSIVHNPGTNAGNAHNHDHKPGDKHDAPAIADGVLRKDEHGPEVKAMQERLNALGYRDAEGKALVADGKFGDRTKHAVEQFQKDHPGLTVDGIAGPNTLRELKTAQPRHDANAGPLLSDPAHRDNAMYQQAVSGLEKLGGFKNHQELERAAATLTYDARISGLTEINHVTRNASGNGLFAVQGELNDPSHKRAYVDANQAVNQSVEQSTQRLQQDVPQSAKQQDQSQQQEQQRNQQVPAKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIF0</accession>
    <name>A0A0S2DIF0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_3042</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3042"/>
    <dbReference type="EnsemblBacteria" id="ALN58389">
        <property type="protein sequence ID" value="ALN58389"/>
        <property type="gene ID" value="GLE_3042"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3042"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3002"/>
    <dbReference type="OMA" id="GWTFVME"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.550">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001129">
        <property type="entry name" value="Membr-assoc_MAPEG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
        <property type="entry name" value="MAPEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="SSF161084"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="142" mass="15760" checksum="895ABD037F8096D6" modified="2016-02-17" version="1">MDTMDTKTIFLPALAMAVLTCVVWLRLFYVRIGQMKRDRIHPQSVATSAQAVAKLTESRAADNFRNLFELPVLFYLALVVAALNGLADTATLTLAWLFVALRIAHSAIQCGYNKVMHRFYAYAAGGLALWLLWARIGVGLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIN5</accession>
    <name>A0A0S2DIN5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Linear gramicidin synthetase subunit C</fullName>
            <ecNumber evidence="7">5.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_2958</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="5.1.1.-" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947938.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2958"/>
    <dbReference type="EnsemblBacteria" id="ALN58306">
        <property type="protein sequence ID" value="ALN58306"/>
        <property type="gene ID" value="GLE_2958"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2958"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2919"/>
    <dbReference type="OMA" id="ERYLEYP"/>
    <dbReference type="OrthoDB" id="572620at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="561"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="1624"/>
            <end position="1699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="541"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="596"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1659"/>
        </location>
    </feature>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN58306.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1709" mass="184317" checksum="ABEC33DE8C92BCC8" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIQ7</accession>
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        </submittedName>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 10">YC36</strain>
        </source>
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    </dbReference>
    <dbReference type="Pfam" id="PF00953">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
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            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="115"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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            <end position="184"/>
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            <end position="315"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW26694.1"/>
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    <evidence type="ECO:0000313" key="9">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="323" mass="34510" checksum="3D1BF81627172158" modified="2016-02-17" version="1">MWAWLAIHAALAAAGTWLARAYALRSRLIDQPGERRSHSVATPRGGGIAIVIALLVATVSLGLKFPAYASLALAFGLGLAAIAAIGWVDDHRPLSPWLRLAVHILAAALLAAAVWHARGDPWLALAAFVFAVGLTNVWNFMDGINGLAASQAALVALALAGFGGPVWSWLALALLAACAGFLPFNFPRARIFMGDVGSGAIGYAVAGLGALAATAQAEPARALVLLIPLAAFMVDSSLTLLRRVRRGERWWTPHTQHAYQVWARRVGHVRVTLAYAIFTLLSLASLHLVTEVRIGFMLCMGAGWYISAAFLWWLIQRTERSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ60</accession>
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        <submittedName>
            <fullName evidence="7">POT family</fullName>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="ALN58457"/>
        <property type="gene ID" value="GLE_3110"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3110"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="72"/>
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            <begin position="1"/>
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        </location>
    </feature>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022856"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN58457.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="558" mass="61210" checksum="E0444B162E310C97" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJG5</accession>
    <name>A0A0S2DJG5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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        <property type="protein sequence ID" value="ALN58424"/>
        <property type="gene ID" value="GLE_3077"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="40" mass="4290" checksum="B15F0EEC53A8E034" modified="2016-02-17" version="1">MHRFQSSSPDRGARGDCRNAGGMGEPVDRTRVLGSGRGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJJ0</accession>
    <name>A0A0S2DJJ0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosomal RNA large subunit methyltransferase H</fullName>
            <ecNumber evidence="3">2.1.1.177</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">23S rRNA (pseudouridine1915-N3)-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">23S rRNA m3Psi1915 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">rRNA (pseudouridine-N3-)-methyltransferase RlmH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">rlmH</name>
        <name evidence="5" type="ORF">BV903_17895</name>
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        <name evidence="6" type="ORF">FE772_16830</name>
        <name evidence="4" type="ORF">GLE_3412</name>
    </gene>
    <organism evidence="4 8">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 8">C3</strain>
        </source>
    </reference>
    <reference evidence="5 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">OH11</strain>
        </source>
    </reference>
    <reference evidence="6 11" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>pseudouridine(1915) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(3)-methylpseudouridine(1915) in 23S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10221"/>
            <dbReference type="Rhea" id="RHEA-COMP:10222"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:74486"/>
            <dbReference type="EC" id="2.1.1.177"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNA methyltransferase RlmH family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.177" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000048">
        <property type="protein sequence ID" value="OPD62544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000024">
        <property type="protein sequence ID" value="ROU07063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948276.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3412"/>
    <dbReference type="EnsemblBacteria" id="ALN58758">
        <property type="protein sequence ID" value="ALN58758"/>
        <property type="gene ID" value="GLE_3412"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62544">
        <property type="protein sequence ID" value="OPD62544"/>
        <property type="gene ID" value="BV903_17895"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3412"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3362"/>
    <dbReference type="OMA" id="NEPYHHQ"/>
    <dbReference type="OrthoDB" id="1783583at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070038">
        <property type="term" value="F:rRNA (pseudouridine-N3-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18081">
        <property type="entry name" value="RlmH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00658">
        <property type="entry name" value="23SrRNA_methyltr_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003742">
        <property type="entry name" value="RlmH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33603">
        <property type="entry name" value="PTHR33603"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02590">
        <property type="entry name" value="SPOUT_MTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004505">
        <property type="entry name" value="MT_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00246">
        <property type="entry name" value="tRNA_RlmH_YbeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 3 5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="3">
        <location>
            <begin position="123"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD62544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW27056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROU07063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="156" mass="17276" checksum="BF4F59BCDF22189D" modified="2016-02-17" version="1">MKSKLIAVGERAPRWVAEGFGEYQKRLSHWLPLELVEIEPGLRGKGRDALRATADEGARVLAALPKNACVVALEGRGRLWTSEQLAQRLEHWRGQGRDLAFLIGGPEGHAPDVLARADEQWSLGPLTLPHMLVRLVAAEQLYRAAALLANHPYHRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJL3</accession>
    <name>A0A0S2DJL3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3247</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58593">
        <property type="protein sequence ID" value="ALN58593"/>
        <property type="gene ID" value="GLE_3247"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3247"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3201"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="91" mass="9020" checksum="DA9A2B23BE4E4D45" modified="2016-02-17" version="1">MAAAGCAGGHVGTGRTGETAVCRAGRAGAATGRAGRTNAQYAARPGRGAAGDCARCGAIARNPHAPRPCGGDGRRGGVASAARARWYRSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJM3</accession>
    <name>A0A0S2DJM3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome C assembly protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Inner membrane protein YpjD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_24605</name>
        <name evidence="5" type="ORF">FE772_16140</name>
        <name evidence="3" type="ORF">GLE_3259</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000096">
        <property type="protein sequence ID" value="OPD61257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948158.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000096.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3259"/>
    <dbReference type="EnsemblBacteria" id="ALN58605">
        <property type="protein sequence ID" value="ALN58605"/>
        <property type="gene ID" value="GLE_3259"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61257">
        <property type="protein sequence ID" value="OPD61257"/>
        <property type="gene ID" value="BV903_24605"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3259"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3212"/>
    <dbReference type="OMA" id="MPGEFIT"/>
    <dbReference type="OrthoDB" id="955123at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002541">
        <property type="entry name" value="Cyt_c_assembly"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01578">
        <property type="entry name" value="Cytochrom_C_asm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_C_asm" evidence="2">
        <location>
            <begin position="41"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD61257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="263" mass="28754" checksum="B6630CF332B0FC7D" modified="2016-02-17" version="1">MTIVLIAIALYLSAAGLLVRAVRRDGGRGARGWLLPANLAVLLHGLAHLMAWRGAGGADLHFFAALSLVGLGMSILTAIVGAAGRMAALGVVVFPLSALMLLAYQLYGHVQHPEPLDWRLQLHAWMALLAYATLAVAALFAVMLWLQESALRRREFHGWLRALPPLVELESLLFRTIAVGFVLLTATLLTGVLFVENLLAQHLMHKTVLSVLSWLAFGGLLLGRWRYGWRGVVAVRWTLAAMALLVLAFFGSKFVLELVLRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK31</accession>
    <name>A0A0S2DK31_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3506</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3506"/>
    <dbReference type="EnsemblBacteria" id="ALN58851">
        <property type="protein sequence ID" value="ALN58851"/>
        <property type="gene ID" value="GLE_3506"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3506"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3450"/>
    <dbReference type="OMA" id="DDPKAHY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595141" evidence="1">
        <location>
            <begin position="29"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="324" mass="35767" checksum="3F522D4EC43A86FC" modified="2016-02-17" version="1">MMRLVARAWRLALLFGLVLSGAWGPAAASPAPHERPGHGHGDDPDAHVLVLGRISDDPKAHYEQLKPLLDYVVPRMAEVGIREGRILMAKDAQQMGSYLRRGRVDWVSETAGTAMLLNQRAGALPLLLTERDGVSHYHSVFFARRDSGLRSLDDLSGHNVAFQRPSSTSAYFVPAATLLERGLRLEILLSPTDRINRGAVGYLFARSELNIATWVHKRLVDAGVMSNLDWDNPRRVPEAFRGDLVLIGRSADYPRALELVRPGLDPKVSARLREVLLEAAGDPDAGEALLRFFKTTRFMPVDPASQRALDRIGHGVAQVRAEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK95</accession>
    <name>A0A0S2DK95_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein PilX</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Type IV pilus assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pilX</name>
        <name evidence="4" type="ORF">FE772_17830</name>
        <name evidence="3" type="ORF">GLE_3623</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948424.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3623"/>
    <dbReference type="EnsemblBacteria" id="ALN58967">
        <property type="protein sequence ID" value="ALN58967"/>
        <property type="gene ID" value="GLE_3623"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3623"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3567"/>
    <dbReference type="OMA" id="THIRRID"/>
    <dbReference type="OrthoDB" id="1774920at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025746">
        <property type="entry name" value="PilX_N_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14341">
        <property type="entry name" value="PilX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="PilX_N" evidence="2">
        <location>
            <begin position="15"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="161" mass="17185" checksum="471401CD497BF975" modified="2016-02-17" version="1">MPSIRLYRAPPRRQRGAALYVALIMLILLALLGLVGMQVTGMQERMSANYGRVSTAFQNAEALARQRETAIRTALYAGGGTFQADEELCSTTYDPSTWANAAASDSATHIRRIDKCVPASSLVVGGKKNEDTGNIYQVSAMRGDLDANAGASAAVDTIFIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKJ1</accession>
    <name>A0A0S2DKJ1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3414</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58760">
        <property type="protein sequence ID" value="ALN58760"/>
        <property type="gene ID" value="GLE_3414"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3414"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3364"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="51" mass="5498" checksum="EBE6656BBB975969" modified="2016-02-17" version="1">MGRRSSHSAAFGRGRPVPAGRRTRPGPAPRPAGDPAAGRRLRTRVRIARAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKM0</accession>
    <name>A0A0S2DKM0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-binding response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Response regulator transcription factor</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator, LuxR/UhpA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BV903_22815</name>
        <name evidence="7" type="ORF">FE772_18435</name>
        <name evidence="5" type="ORF">GLE_3744</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000077">
        <property type="protein sequence ID" value="OPD61576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948516.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000077.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3744"/>
    <dbReference type="EnsemblBacteria" id="ALN59088">
        <property type="protein sequence ID" value="ALN59088"/>
        <property type="gene ID" value="GLE_3744"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61576">
        <property type="protein sequence ID" value="OPD61576"/>
        <property type="gene ID" value="BV903_22815"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3744"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3688"/>
    <dbReference type="OMA" id="DVWVPPD"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="7"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="144"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD61576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW27321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="225" mass="23867" checksum="C447D98CC77B6484" modified="2016-02-17" version="1">MADAALRILIADDHPMFRAALRYALGEIAPGAHIVEVASQSALEAAIGSGEAFDLAMLDLMMPGAMGFSSLVYARGERPELPVVIISSNEHPRTIRRAQQFGASGFVPKSAPAAVLAEAVGAVLAGRVWFSPQQAERDEGDAQLADRLAQLTPQQMRVLLRLADGLLNKQIAYELSLAENTVKIHVTAILRKLGCHSRTQAAVLVKGLSLEEDGGELHDGVGGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKM5</accession>
    <name>A0A0S2DKM5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">N-acetyl-D-glucosamine kinase (GlcNAc kinase)</fullName>
            <ecNumber evidence="1">2.7.1.59</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3657</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.1.59" evidence="1"/>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <source>
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        <source>
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        <source>
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</entry>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <location>
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            <begin position="504"/>
            <end position="682"/>
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            <dbReference type="Pfam" id="PF00535"/>
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            <dbReference type="EMBL" id="ALN59222.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="790" mass="87875" checksum="CE9BF045C51C8DEC" modified="2016-02-17" version="1"> </sequence>
</entry>
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        <recommendedName>
            <fullName evidence="1 2">50S ribosomal protein L24</fullName>
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            <taxon>Bacteria</taxon>
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    <reference evidence="4 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 10">C3</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="journal article" date="2016" name="DNA Res." volume="0" first="0" last="0">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer, Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">M497-1</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="3">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">ATCC 29487</strain>
        </source>
    </reference>
    <reference evidence="5 13" key="4">
        <citation type="journal article" date="2017" name="DNA Res." volume="24" first="169" last="177">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
            <dbReference type="PubMed" id="28065880"/>
            <dbReference type="DOI" id=".1093/dnares/dsw055"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 13">M497-1</strain>
        </source>
    </reference>
    <reference evidence="6 12" key="5">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 12">B25</strain>
        </source>
    </reference>
    <reference evidence="8 14" key="6">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 14">OH11</strain>
        </source>
    </reference>
    <reference evidence="7 15" key="7">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="2">One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Part of the 50S ribosomal subunit.</text>
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    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="NZ_RCTY01000023.1"/>
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        <property type="protein sequence ID" value="ALN59123"/>
        <property type="gene ID" value="GLE_3779"/>
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        <property type="gene ID" value="BV903_22980"/>
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        <property type="protein sequence ID" value="SDY03287"/>
        <property type="gene ID" value="SAMN05421681_11014"/>
    </dbReference>
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    <dbReference type="KEGG" id="lez:GLE_3779"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3723"/>
    <dbReference type="OMA" id="HVKPTQE"/>
    <dbReference type="OrthoDB" id="2040741at2"/>
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    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="project" value="InterPro"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Ribosomal_L24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17136">
        <property type="entry name" value="ribosomal_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="rplX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
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        <location>
            <begin position="3"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029550"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAV96851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD61606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW27350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROU07192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="SDY03287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000183696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000218824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="104" mass="11283" checksum="62382F97A2545C66" modified="2016-02-17" version="1">MNRIKKGDQVIVTAGKDKGKKGDVVRVLGDKVVVSNINIVKRHTKPNPQANQPGGVVEREAPIHISNVMLFNPATGKGERIGFKVLEDGRKLRVFRSSGEAVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKV8</accession>
    <name>A0A0S2DKV8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_17445</name>
        <name evidence="2" type="ORF">GLE_3544</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58888">
        <property type="protein sequence ID" value="ALN58888"/>
        <property type="gene ID" value="GLE_3544"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3544"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3488"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="117" mass="12304" checksum="2219E10F8AF71F4F" modified="2016-02-17" version="1">MKAANWVQDTFRALPRYLFVLTAVSALALLARAAVPSFSRASAADSESLVSELRGPPRELVAPAAAPAAARTIAAAASGSRLAAQARLPEPVRSRSPTPAHRYSPVESQLKRTRGAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKX3</accession>
    <name>A0A0S2DKX3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Outer-membrane lipoprotein LolB</fullName>
        </recommendedName>
    </protein>
    <gene>
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        <name evidence="14" type="ORF">GLE_3811</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 12">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell outer membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the LolB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3811"/>
    <dbReference type="EnsemblBacteria" id="ALN59154">
        <property type="protein sequence ID" value="ALN59154"/>
        <property type="gene ID" value="GLE_3811"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3811"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3754"/>
    <dbReference type="OMA" id="YQTRGSF"/>
    <dbReference type="OrthoDB" id="1797257at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044874">
        <property type="term" value="P:lipoprotein localization to outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16326">
        <property type="entry name" value="LolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00233">
        <property type="entry name" value="LolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029046">
        <property type="entry name" value="LolA/LolB/LppX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004565">
        <property type="entry name" value="OM_lipoprot_LolB"/>
    </dbReference>
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        <property type="entry name" value="LolB"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF89392"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00548">
        <property type="entry name" value="lolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="12" id="KW-0143">Chaperone</keyword>
    <keyword evidence="11 14" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0564">Palmitate</keyword>
    <keyword evidence="8 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0732">Signal</keyword>
    <keyword evidence="6 12" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5008854163" description="Outer-membrane lipoprotein LolB" evidence="13">
        <location>
            <begin position="27"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN59154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="220" mass="22413" checksum="E2EAB1C0B1F386F0" modified="2016-02-17" version="1">MTEAAVAARVRLVAGLLLTAVLAACAGPGVRPGAPAGQVVPAADAAEREAARSARVRAAADWSLTGRIAVSNAGKGGSGRIEWSQRGAGFDVALSAPVTRQSWRLSGAPGSARLEGLDGGPREGADATELLFQATGWDIPVAALGDWLRGLPAGGDGGDARILPGPDGRPQSIAQGGWTIAYEWPATGDLPTRLDARRDSARVRLIVDRWQGGAAEAATP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKY5</accession>
    <name>A0A0S2DKY5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_23440</name>
        <name evidence="4" type="ORF">FE772_18845</name>
        <name evidence="2" type="ORF">GLE_3827</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000082">
        <property type="protein sequence ID" value="OPD61482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948582.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000082.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59170">
        <property type="protein sequence ID" value="ALN59170"/>
        <property type="gene ID" value="GLE_3827"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61482">
        <property type="protein sequence ID" value="OPD61482"/>
        <property type="gene ID" value="BV903_23440"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3827"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3769"/>
    <dbReference type="OrthoDB" id="1293522at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="359" mass="38149" checksum="EB97D5EA5925F1AB" modified="2016-02-17" version="1">MLPIDAYRPTNFPVCTPTPPPADPRAPELKPVQADSGPNDFEIGVQGPDPDLAVGGSHDQQESQRDFMLALASRGFASYLTGHTPGTPRYPGDGDVRNILQDLQPNPPIGEVGREVTRAVYQSDIPNATPQEAYDHFVQNPGEVFGAGGMEIRPPTQNLEDGGRYMLETGGPPPTWLPVEIRLDADNRAITINTLDGHVLRGTQTFTFTDNCSGGTTLTQDASFQGSTPLVGDIQELASVSAGQHNAWQNAHREIYGQFNGDQDYTGIGTSAVSPELIKGWGQMLLNIAADPGRAGDVLLDSGGELANETIDHWGGWAGDFMDWAGIPGGGVVRDVTDAVGDGISATADKVGDVIDFVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL31</accession>
    <name>A0A0S2DL31_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Dihydrofolate reductase</fullName>
            <ecNumber evidence="3 7">1.5.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">folA</name>
        <name evidence="11" type="ORF">FE772_19235</name>
        <name evidence="10" type="ORF">GLE_3918</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(6S)-5,6,7,8-tetrahydrofolate + NADP(+) = 7,8-dihydrofolate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15009"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57451"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 5,6,7,8-tetrahydrofolate from 7,8-dihydrofolate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the dihydrofolate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.3" evidence="3 7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3918"/>
    <dbReference type="EnsemblBacteria" id="ALN59260">
        <property type="protein sequence ID" value="ALN59260"/>
        <property type="gene ID" value="GLE_3918"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3918"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3855"/>
    <dbReference type="OMA" id="RDNQLPW"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00158"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004146">
        <property type="term" value="F:dihydrofolate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006545">
        <property type="term" value="P:glycine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00209">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012259">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017925">
        <property type="entry name" value="DHFR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001796">
        <property type="entry name" value="DHFR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069">
        <property type="entry name" value="PTHR48069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00186">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000194">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00075">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51330">
        <property type="entry name" value="DHFR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="5 7 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHFR" evidence="9">
        <location>
            <begin position="4"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW27454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="169" mass="18649" checksum="BCF4E6B43EE7351C" modified="2016-02-17" version="1">MTLQLSLIAALDRNHAIGRDNALPWRLSDDLKRFKALTLGKPLLMGRKTAQSLGRALPGRRNLVLTRSGEVPFAGMEAVGSTEQALELAAADGAAELCVIGGGEVYALCLPSATRLYLTRVDTEVAGADAFFPRLDPAEWRETARERHRADERNEFDFEYVDYVRLGMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLH6</accession>
    <name>A0A0S2DLH6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Ribosomal RNA small subunit methyltransferase E</fullName>
            <ecNumber evidence="4 10">2.1.1.193</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">GLE_3947</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>S-adenosyl-L-methionine + uridine(1498) in 16S rRNA = H(+) + N(3)-methyluridine(1498) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42920"/>
            <dbReference type="Rhea" id="RHEA-COMP:10283"/>
            <dbReference type="Rhea" id="RHEA-COMP:10284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74502"/>
            <dbReference type="EC" id="2.1.1.193"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the RNA methyltransferase RsmE family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.193" evidence="4 10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3947"/>
    <dbReference type="EnsemblBacteria" id="ALN59289">
        <property type="protein sequence ID" value="ALN59289"/>
        <property type="gene ID" value="GLE_3947"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3947"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3884"/>
    <dbReference type="OMA" id="TQWKGER"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006700">
        <property type="entry name" value="rRNA_ssu_MeTrfase-E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30027">
        <property type="entry name" value="PTHR30027"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04452">
        <property type="entry name" value="Methyltrans_RNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015601">
        <property type="entry name" value="MTase_slr0722"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00046">
        <property type="entry name" value="TIGR00046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="8 10" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR015601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN59289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="240" mass="25464" checksum="C4BFF8F44AACA1F7" modified="2016-02-17" version="1">MHVETDLAPGREVALPEGPATHLARVLRHEVGDACVLFNGDGRDYHGRISAIGKREVRVAIDSAHEIARESPLRLVLLQGVARGEKMDLILQKATELGASAFHPLWSQRSEVKLDAARADKRLAHWRSVVASACEQSGRATVPEVAAPLALAAALTALAPGGLRLILDPDGELAFSTLQVDTTAPVLLAIGPEGGWSPLDREQLRAAGFQGLRLGPRILRTETAGLAAIAALQARFGDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLL4</accession>
    <name>A0A0S2DLL4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cell division protein FtsL</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">ftsL</name>
        <name evidence="9" type="ORF">BV903_07620</name>
        <name evidence="10" type="ORF">FE772_20280</name>
        <name evidence="8" type="ORF">GLE_4137</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of a complex composed of FtsB, FtsL and FtsQ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell inner membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <text evidence="6">Localizes to the division septum where it forms a ring structure.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the FtsL family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000015">
        <property type="protein sequence ID" value="OPD64523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948815.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4137"/>
    <dbReference type="EnsemblBacteria" id="ALN59479">
        <property type="protein sequence ID" value="ALN59479"/>
        <property type="gene ID" value="GLE_4137"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64523">
        <property type="protein sequence ID" value="OPD64523"/>
        <property type="gene ID" value="BV903_07620"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4137"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4079"/>
    <dbReference type="OMA" id="SYSAHWN"/>
    <dbReference type="OrthoDB" id="1803426at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00910">
        <property type="entry name" value="FtsL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011922">
        <property type="entry name" value="Cell_div_FtsL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37479">
        <property type="entry name" value="PTHR37479"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04999">
        <property type="entry name" value="FtsL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02209">
        <property type="entry name" value="ftsL_broad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6 8" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD64523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="87" mass="10178" checksum="450FD5C6E7ED4EC5" modified="2016-02-17" version="1">MMRLLLILLIVANVASALLVVFARHEHRQLFVQLNKLQRERDELNIEFGRLQLEQATWAESNRIDQVARERIGMRFPEGAETVVIRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLL9</accession>
    <name>A0A0S2DLL9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FeS assembly SUF system protein SufT</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Putative Fe-S cluster assembly protein SufT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">sufT</name>
        <name evidence="3" type="ORF">BV903_16030</name>
        <name evidence="5" type="ORF">D9T17_09130</name>
        <name evidence="4" type="ORF">FE772_18955</name>
        <name evidence="2" type="ORF">GLE_3856</name>
    </gene>
    <organism evidence="2 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">C3</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 9" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000042">
        <property type="protein sequence ID" value="OPD62901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000022">
        <property type="protein sequence ID" value="ROU07452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948599.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000022.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3856"/>
    <dbReference type="EnsemblBacteria" id="ALN59199">
        <property type="protein sequence ID" value="ALN59199"/>
        <property type="gene ID" value="GLE_3856"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62901">
        <property type="protein sequence ID" value="OPD62901"/>
        <property type="gene ID" value="BV903_16030"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3856"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3796"/>
    <dbReference type="OMA" id="PWSREMM"/>
    <dbReference type="OrthoDB" id="1668114at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017776">
        <property type="entry name" value="FeS_assembly_SufT_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03406">
        <property type="entry name" value="FeS_long_SufT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeS_assembly_P" evidence="1">
        <location>
            <begin position="86"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU07452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="183" mass="20206" checksum="FEC22AC9DA4EDE2A" modified="2016-02-17" version="1">MYSRSSEPVRFERDCAVVMVPQGEQVTLPAGSVGYITQALGGSYTVFVEGNLFRIHGRDADAIGKEPPEPLELPEGADDEAVERLVWQQLRTCFDPEIPINVVELGLVYEAAVKHRDDGQRTVEVRMTLTAPGCGMGDILVDDVRSKLEMIPTVAEADVELVFDPPWNRNMMSEAARLETGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLQ3</accession>
    <name>A0A0S2DLQ3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide repeat domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3971"/>
    <dbReference type="EnsemblBacteria" id="ALN59313">
        <property type="protein sequence ID" value="ALN59313"/>
        <property type="gene ID" value="GLE_3971"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3971"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3908"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595814" evidence="1">
        <location>
            <begin position="28"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="209" mass="22333" checksum="4DE67D9AD01C5183" modified="2016-02-17" version="1">MIRTTQRAARRGAVLAALTAAVLAALAAACSVAPPQPSALAEANFNGEAAVAQVRAAGGAAARELDVQPLRDSQVEDLRQKAEVLEKSRKYPEAAAALDQALQINADDPALLQERAEAALLLHRLDDAERFAQKAYDGGSQVGPLCRRHWAAIAQARQGRLDGVNAAMKLAKRQDHYDALVPQRDGLIRSRKQAQDKIDACTVAAPARY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLZ2</accession>
    <name>A0A0S2DLZ2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, ArsR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_21485</name>
        <name evidence="2" type="ORF">GLE_4398</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="69.GLE_4398"/>
    <dbReference type="EnsemblBacteria" id="ALN59739">
        <property type="protein sequence ID" value="ALN59739"/>
        <property type="gene ID" value="GLE_4398"/>
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    <dbReference type="KEGG" id="lez:GLE_4398"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="8"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="121" mass="13451" checksum="7A9DE7A54AD52521" modified="2016-02-17" version="1">MSVRAPRRREPDPAQLDRLFHALADASRRQMIDRLSAGPASVSELAQPLAMALPSVVKHLAVLESGGIVASEKRGRVRTYRIAPDALALVETWIAERKARYQSQFDALERYLASQPDEDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMC0</accession>
    <name>A0A0S2DMC0_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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        <name evidence="3" type="ORF">GLE_4401</name>
    </gene>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59742">
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        <property type="gene ID" value="GLE_4401"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4401"/>
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    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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            <begin position="23"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="330" mass="37340" checksum="7F5DD3E8C676E45A" modified="2016-02-17" version="1">MNKKLLPVVLCGLIAAPLSAWAEDSEKESPPEEWELAERSDPMTEPVKKFLKVLEDLDRRYPDSAKIDVARFMETEGEAVAQAYCNVLGFDGPCVPEDRKGDEVFVAYSPEHSAAKRALGWWDWLTMRFTNVGIIPHNNACPAGYAWTEIRMDDEDRRNANRREGWIGATVSNANTSWRFCKVSTFKSMQYRPLPQAGNRYDYAVLNMGLFCPSGARRYTRVQTNEVWNNQNGSYGGVFPNFRVYNTWFTLYCHFDGGASSALGHMTTFPQHGFAHGVFAPLSMPTHPLGAGYVHQDDEDLVNWNSWLLGSPDEIMGGGRNTLRYLMRVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMI8</accession>
    <name>A0A0S2DMI8_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Flagellar C-ring protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="primary">fliG</name>
        <name evidence="2" type="ORF">GLE_4638</name>
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        <lineage>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59979.1"/>
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    </dbReference>
    <dbReference type="RefSeq" id="WP_057949202.1">
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59979">
        <property type="protein sequence ID" value="ALN59979"/>
        <property type="gene ID" value="GLE_4638"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4638"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4574"/>
    <dbReference type="OrthoDB" id="2207330at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0282">Flagellum</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="182" mass="19080" checksum="16E8965BE5A063E3" modified="2016-02-17" version="1">MSGLETNRPDGARGKSERELRRTVGRLSQCSIEDIEAIWSQLDPREQAQLRPLLAEASGSLPESALGALPAVSQAAAEAAPASLPPAFGHYLAQLPETVAASVLASLDASAREAALQALPDPARRESLRAAAAPLRLRPAARRALHDAALAAAREAAPAPIQAPAETAPRGLSRLWRRSARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMR1</accession>
    <name>A0A0S2DMR1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Entericidin</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Entericidin A/B family lipoprotein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Entericidin EcnA/B family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BV903_23150</name>
        <name evidence="8" type="ORF">FE772_21175</name>
        <name evidence="6" type="ORF">GLE_4332</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">C3</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EcnA/EcnB lipoprotein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD61521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948968.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000079.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4332"/>
    <dbReference type="EnsemblBacteria" id="ALN59673">
        <property type="protein sequence ID" value="ALN59673"/>
        <property type="gene ID" value="GLE_4332"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61521">
        <property type="protein sequence ID" value="OPD61521"/>
        <property type="gene ID" value="BV903_23150"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4332"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4271"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009636">
        <property type="term" value="P:response to toxic substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Entericidin"/>
    </dbReference>
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        <property type="entry name" value="Entericidin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595400" evidence="5">
        <location>
            <begin position="21"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD61521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW27784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="49" mass="5161" checksum="5069BB22BF9C9296" modified="2016-02-17" version="1">MKRLTALLLLALFSIGSLTACNTIAGAGKDVKKAGEKVEEKAEDVRDGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN24</accession>
    <name>A0A0S2DN24_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Porphobilinogen deaminase</fullName>
            <shortName evidence="8">PBG</shortName>
            <ecNumber evidence="8">2.5.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Hydroxymethylbilane synthase</fullName>
            <shortName evidence="8">HMBS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Pre-uroporphyrinogen synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">hemC</name>
        <name evidence="12" type="ORF">FE772_22215</name>
        <name evidence="11" type="ORF">GLE_4552</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8">Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>H2O + 4 porphobilinogen = hydroxymethylbilane + 4 NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57845"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="EC" id="2.5.1.61"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>dipyrromethane</name>
            <dbReference type="ChEBI" id="CHEBI:60342"/>
        </cofactor>
        <text evidence="8">Binds 1 dipyrromethane group covalently.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 8">Monomer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">The porphobilinogen subunits are added to the dipyrromethane group.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the HMBS family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.61" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949141.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4552"/>
    <dbReference type="EnsemblBacteria" id="ALN59893">
        <property type="protein sequence ID" value="ALN59893"/>
        <property type="gene ID" value="GLE_4552"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4552"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4488"/>
    <dbReference type="OMA" id="LWQANHI"/>
    <dbReference type="OrthoDB" id="1450400at2"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00319"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004418">
        <property type="term" value="F:hydroxymethylbilane synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018160">
        <property type="term" value="P:peptidyl-pyrromethane cofactor linkage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00260">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000860">
        <property type="entry name" value="HemC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022419">
        <property type="entry name" value="Porphobilin_deaminase_cofac_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022417">
        <property type="entry name" value="Porphobilin_deaminase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022418">
        <property type="entry name" value="Porphobilinogen_deaminase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036803">
        <property type="entry name" value="Porphobilinogen_deaminase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11557">
        <property type="entry name" value="PTHR11557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01379">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03900">
        <property type="entry name" value="Porphobil_deamC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001438">
        <property type="entry name" value="4pyrrol_synth_OHMeBilane_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00151">
        <property type="entry name" value="PORPHBDMNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54782">
        <property type="entry name" value="SSF54782"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00212">
        <property type="entry name" value="hemC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00533">
        <property type="entry name" value="PORPHOBILINOGEN_DEAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Porphobil_deam" evidence="9">
        <location>
            <begin position="4"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Porphobil_deamC" evidence="10">
        <location>
            <begin position="224"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="modified residue" description="S-(dipyrrolylmethanemethyl)cysteine" evidence="8">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN59893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW27956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="313" mass="33429" checksum="7AFA5C63451C7186" modified="2016-02-17" version="1">MKTLRIATRKSPLALWQSEHVADRLRAAHPGLTVTLVPMSTRGDEVLDRSLAAIGGKGLFLKELELAMQRGEADCAVHSLKDVPMELDPGFALPAVLERADYADAFVSNHHDGIENLPPGARVGTSSLRRQAQLRALRPDLQLQDLRGNVNTRLAKLDAGDYDAIVLACAGLQRLGLDARIRRRLEAPHWLPAPAQGAIAVECREDDAATRALCAALDHAATRTCVEAERAMNRSLHGSCHVPVAAYAWLDGEHLRLDGQVGSAGDGRSVRAHGEGRGDAPQCLGIEVAGRLLEQGAGEFIAASLQGGPGEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN36</accession>
    <name>A0A0S2DN36_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flagellar C-ring protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fliM</name>
        <name evidence="2" type="ORF">GLE_4645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949209.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59986">
        <property type="protein sequence ID" value="ALN59986"/>
        <property type="gene ID" value="GLE_4645"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4645"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4581"/>
    <dbReference type="OrthoDB" id="2126859at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001543">
        <property type="entry name" value="FliN-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036429">
        <property type="entry name" value="SpoA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01052">
        <property type="entry name" value="FliMN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101801">
        <property type="entry name" value="SSF101801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0282">Flagellum</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FliMN_C" evidence="1">
        <location>
            <begin position="199"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="279" mass="29216" checksum="E22ED827BA184350" modified="2016-02-17" version="1">MSAAADVSSRGAEAAPRWRPLGQADADWLRERAAQALRAWQDEWFDAGAFDVLDAQAFAPGQAFADGGACWRAGTSLAAQTEPGAWKRHALAAMALSAQADAQVPEALLAPLQAQMLDALLARLADALADGSPGVRAGFERALPGDNPGFAAGGVRLRIGTARDPQLLDLYCAAELAWTRPLSAAPAAKPAAPTARAEALGDNPVRLSAVLGRCRLTALQLSELAVGDVLTTAQSLHEPIALRLHADGVAPRTIAHGRPGRAQQRLSIELTTLQQKRTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN37</accession>
    <name>A0A0S2DN37_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldehyde dehydrogenase (NAD) family protein</fullName>
            <ecNumber evidence="3">1.2.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4607</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.2.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949177.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4607"/>
    <dbReference type="EnsemblBacteria" id="ALN59948">
        <property type="protein sequence ID" value="ALN59948"/>
        <property type="gene ID" value="GLE_4607"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4607"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4542"/>
    <dbReference type="OMA" id="FDLCAQR"/>
    <dbReference type="OrthoDB" id="618655at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="2">
        <location>
            <begin position="21"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="535" mass="55197" checksum="CF295821725ED37E" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNE2</accession>
    <name>A0A0S2DNE2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DegV family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_23370</name>
        <name evidence="2" type="ORF">GLE_4809</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949330.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4809"/>
    <dbReference type="EnsemblBacteria" id="ALN60150">
        <property type="protein sequence ID" value="ALN60150"/>
        <property type="gene ID" value="GLE_4809"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4809"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4741"/>
    <dbReference type="OMA" id="HYAESIP"/>
    <dbReference type="OrthoDB" id="1288126at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003797">
        <property type="entry name" value="DegV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043168">
        <property type="entry name" value="DegV_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02645">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00762">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51482">
        <property type="entry name" value="DEGV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="315" mass="34841" checksum="20B02E3C28A3AE1F" modified="2016-02-17" version="1">MRIGIVVDSACDLPLEYLQQHHIHLLPITVRIGQAVLADHRNEEATLQFLQAHLAERGFEAETTPFTVQQVRDLFVSQLAIDYDYVFCMTITKTRSPVFENANQASFAILNDYKPVRSAAGFNTPFSLRVIDTLNLFAAQGVTAVEAVRMRAAEEPPPKIRARLEQLVNATHGYLIPRDLNYLRARTRHRGDRSVSFLSATLGTALDIKPVLHCNRGETGPIAKIKTYEAAAQKLLKFAARRVSRNELLTPTVCLSYGGELAELRALPGYQTLRLACEQHGVELFESLMSLTGMVNIGKGALALGLATEQAAWDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNJ9</accession>
    <name>A0A0S2DNJ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_22965</name>
        <name evidence="2" type="ORF">GLE_4724</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949262.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4724"/>
    <dbReference type="EnsemblBacteria" id="ALN60065">
        <property type="protein sequence ID" value="ALN60065"/>
        <property type="gene ID" value="GLE_4724"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4724"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4658"/>
    <dbReference type="OMA" id="FYGMESW"/>
    <dbReference type="OrthoDB" id="1914312at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013538">
        <property type="entry name" value="Activator_of_Hsp90_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08327">
        <property type="entry name" value="AHSA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="168" mass="19195" checksum="95E87DA0D2FE086A" modified="2016-02-17" version="1">MTSDGSSTLAVAPARTTHRIEERSITLQRIIHAPRELAFLAWTDPVHVARWWGPHGFRSVVREMDVRVGGQFRICMVGPDGAEYPIKGVYRQILEPDRLVYTDDWDDERPPQPSEVTVDFAEQGPEETLLTVAIVFPDREERELAQEMGTVPSWSDSFERLDAYLAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNM6</accession>
    <name>A0A0S2DNM6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Threonylcarbamoyl-AMP synthase</fullName>
            <shortName evidence="7">TC-AMP synthase</shortName>
            <ecNumber evidence="7">2.7.7.87</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">L-threonylcarbamoyladenylate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">tRNA threonylcarbamoyladenosine biosynthesis protein TsaC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tsaC</name>
        <name evidence="9" type="ORF">GLE_4853</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + hydrogencarbonate + L-threonine = diphosphate + H2O + L-threonylcarbamoyladenylate</text>
            <dbReference type="Rhea" id="RHEA:36407"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="EC" id="2.7.7.87"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the SUA5 family. TsaC subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.87" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949361.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4853"/>
    <dbReference type="EnsemblBacteria" id="ALN60194">
        <property type="protein sequence ID" value="ALN60194"/>
        <property type="gene ID" value="GLE_4853"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4853"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4783"/>
    <dbReference type="OMA" id="LVDAFWP"/>
    <dbReference type="OrthoDB" id="1913202at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061710">
        <property type="term" value="F:L-threonylcarbamoyladenylate synthase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01852">
        <property type="entry name" value="TsaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023535">
        <property type="entry name" value="TC-AMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="YrdC-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17490:SF8">
        <property type="entry name" value="PTHR17490:SF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="YrdC-like" evidence="8">
        <location>
            <begin position="5"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN60194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="188" mass="19453" checksum="90206FD35F27AE6A" modified="2016-02-17" version="1">MTASSLSIEQAAAALARGGVLVYPTEAVWGIGCDPFDRAAVLRLLAIKQRPVDKGVILIAASVAQFDALIDWDALPPERAQAVRASWPGPHTWAVPATPAVPAWISGEHRSVALRVSAHPQAAALCRAHGGPLVSTSANLAGQPPAFRREQLDRAVLALADGVCEGETGGLAAPTPIRVALSGEVLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNR8</accession>
    <name>A0A0S2DNR8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4742</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949279.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60083">
        <property type="protein sequence ID" value="ALN60083"/>
        <property type="gene ID" value="GLE_4742"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4742"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4676"/>
    <dbReference type="OrthoDB" id="1817618at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595463" evidence="2">
        <location>
            <begin position="22"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="239" mass="24369" checksum="36AFC843966C4E26" modified="2016-02-17" version="1">MKIAPSLLALAIGLLTLGVQAEETKPRFRVHNTDPAPAARAPAKAPAAAAATAPAAAAPAARPSPTGSTAPASKPAPAPATLSSSGKPAGAQRAPWDTARVAASAVPAVYLAEWKKAKNRARCAPLALVGGEKTPGVTVRRANFSDGWAVAYDLPGQRSAYGVAGTGLDLDGKGYTFPNSLTFADGSSAHYGLSGGTGPGYIAYVEVAGQRCLYNVWADVGGQERLEELLRSLRLVQTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNS9</accession>
    <name>A0A0S2DNS9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DUF4156 domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_12080</name>
        <name evidence="5" type="ORF">FE772_24090</name>
        <name evidence="3" type="ORF">GLE_4970</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000029">
        <property type="protein sequence ID" value="OPD63693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4970"/>
    <dbReference type="EnsemblBacteria" id="ALN60311">
        <property type="protein sequence ID" value="ALN60311"/>
        <property type="gene ID" value="GLE_4970"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63693">
        <property type="protein sequence ID" value="OPD63693"/>
        <property type="gene ID" value="BV903_12080"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4970"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4897"/>
    <dbReference type="OMA" id="AIWVPNP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595467" evidence="2">
        <location>
            <begin position="19"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD63693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW28270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="162" mass="16689" checksum="E905E7B244DD2128" modified="2016-02-17" version="1">MRTPLLLLVLALGLSACASSHVITGQPRPPVPLEQVRVYFAPPPSRYEEIALLQSNSGAFTYGEQNKMNSVINKLRAEAAKLGANGVLFQGTQDGDGGTGVSVGAGGGSYGGGRHFSGGGVGVSISPRQKFARGVAIYVLNPPPMSDRGPQGLPPPPPPSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNZ4</accession>
    <name>A0A0S2DNZ4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acriflavine resistance protein A</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Efflux RND transporter periplasmic adaptor subunit</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Efflux transporter periplasmic adaptor subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BV903_15870</name>
        <name evidence="9" type="ORF">FE772_22830</name>
        <name evidence="7" type="ORF">GLE_4690</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000041">
        <property type="protein sequence ID" value="OPD62948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949240.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4690"/>
    <dbReference type="EnsemblBacteria" id="ALN60031">
        <property type="protein sequence ID" value="ALN60031"/>
        <property type="gene ID" value="GLE_4690"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62948">
        <property type="protein sequence ID" value="OPD62948"/>
        <property type="gene ID" value="BV903_15870"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4690"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4625"/>
    <dbReference type="OMA" id="INVRYTK"/>
    <dbReference type="OrthoDB" id="1579676at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043602">
        <property type="entry name" value="CusB_dom_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00529">
        <property type="entry name" value="CusB_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595041" evidence="4">
        <location>
            <begin position="27"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="CusB_dom_1" evidence="5">
        <location>
            <begin position="53"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="6">
        <location>
            <begin position="69"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="375"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="110"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN60031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD62948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW28054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="397" mass="41028" checksum="25483CBAAD98D46F" modified="2016-02-17" version="1">MPSRKSMSYKAIFTVSALALALAACGKGGDQQGGPGGPGGQKGQVTVVTLKPETITLTRELPGRTSASLVAQVRPQVNGIVEKRLFTEGGLVKAGQPLYQLDDKTYAADAENAKATLARAEASLNSAQLNARRSTELVKIDAVSKQDDENATATLKQARADVAAGRAQVASTGVILGRARIVSPISGRIGKSAVTAGALVTANQADALAVVQQLDPVFVDISQSSAELLALRKQIAAGTLSEASTPVQILLEDGSRYEHDGKLAFSEVTVDEGTGSFLLRVVVPNPDNILMPGMYVRAQVGTGVRQNALLVPQQGVTRDPKGNATALVVNAKSEVEPREIKVGQAIGDKWLVEGGLKAGDKVIVEGLQKIGPGMPVDATEKGAAPAKPAAPAAAPKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP12</accession>
    <name>A0A0S2DP12_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hep/Hag repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_4981</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60322">
        <property type="protein sequence ID" value="ALN60322"/>
        <property type="gene ID" value="GLE_4981"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4981"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4908"/>
    <dbReference type="OMA" id="HHALGVD"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008640">
        <property type="entry name" value="Adhesin_Head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05658">
        <property type="entry name" value="YadA_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101967">
        <property type="entry name" value="SSF101967"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595348" evidence="2">
        <location>
            <begin position="28"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="YadA_head" evidence="3">
        <location>
            <begin position="104"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="315" mass="30588" checksum="6D2E282A6482FD0E" modified="2016-02-17" version="1">MNRSTLLALAIASVIAMNMAAPGQAFAGNDCDLNDGVAGNENSGGSTANGVDAIACGRGNNANADGGVALGRNNTVDGIDAQAIGNGNFAGGVSATAVGADNAASGDESVALGRGNHAAAANASAVGYINSANAQDSSALGNFNFADGVGSNAVGRGNRARVDRSNAFGGDNDVGGVDATALGNNNVASGARSLAAGFGAQAGADDAVAVGVAASASGINSSAFGNGAQAIGVNATAVGASSVAQRRRRPPPRSAGQPGPSARARRRWATSIVRTCKTAARWATSTSPTASARTRWAAATARARIARMRSAATTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPA2</accession>
    <name>A0A0S2DPA2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycoside hydrolase family 3 protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Glycosyl hydrolase, family 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_24870</name>
        <name evidence="7" type="ORF">GLE_5129</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949577.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5129"/>
    <dbReference type="EnsemblBacteria" id="ALN60470">
        <property type="protein sequence ID" value="ALN60470"/>
        <property type="gene ID" value="GLE_5129"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5129"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5054"/>
    <dbReference type="OMA" id="PMWVNAE"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041443">
        <property type="entry name" value="Exop_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18559">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
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    </dbReference>
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        <property type="entry name" value="SSF52279"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
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        <location>
            <begin position="43"/>
            <end position="862"/>
        </location>
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        <location>
            <begin position="79"/>
            <end position="408"/>
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    </feature>
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            <begin position="449"/>
            <end position="662"/>
        </location>
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        <location>
            <begin position="697"/>
            <end position="847"/>
        </location>
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            <dbReference type="ARBA" id="ARBA00022801"/>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN60470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW28403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
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    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="862" mass="91716" checksum="9C1FF91020E7A67F" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ56</accession>
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        <name evidence="5" type="ORF">BV903_05050</name>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 7">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_5365"/>
    <dbReference type="EnsemblBacteria" id="ALN60706">
        <property type="protein sequence ID" value="ALN60706"/>
        <property type="gene ID" value="GLE_5365"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65104">
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        <property type="gene ID" value="BV903_05050"/>
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    <dbReference type="PATRIC" id="fig|69.6.peg.5280"/>
    <dbReference type="OMA" id="DLRILVM"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
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            <end position="369"/>
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        <location>
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            <end position="848"/>
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            <begin position="822"/>
            <end position="840"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60706.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="OPD65104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="848" mass="92951" checksum="774D135E095C32FD" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ90</accession>
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        <submittedName>
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    <organism evidence="5 6">
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    <reference evidence="5 6" key="1">
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN60790">
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        <property type="gene ID" value="GLE_5449"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5449"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5364"/>
    <dbReference type="OMA" id="AALQWKL"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019239">
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595566" evidence="3">
        <location>
            <begin position="22"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="domain" description="A_deaminase" evidence="4">
        <location>
            <begin position="225"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="535" mass="56770" checksum="DDA14974210C4550" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQI8</accession>
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        <submittedName>
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        </submittedName>
    </protein>
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    </gene>
    <organism evidence="1 3">
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        <lineage>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60830">
        <property type="protein sequence ID" value="ALN60830"/>
        <property type="gene ID" value="GLE_5489"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5489"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5404"/>
    <dbReference type="OMA" id="ITPACDL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="647" mass="72891" checksum="F18F436A8CD54178" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DRG2</accession>
    <name>A0A0S2DRG2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF1190 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_05345</name>
        <name evidence="4" type="ORF">FE772_00410</name>
        <name evidence="2" type="ORF">GLE_5435</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
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    <evidence type="ECO:0000313" key="2">
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24357.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="211" mass="22378" checksum="44BACA1D140EA7F4" modified="2016-02-17" version="1">MTTNAHDSAPRGKRSRNLKLVLMAVAAPAVLAGCDDDPSGKILLSREECAVQTEISREECEKAYGQALVEHEKVAPRFESQQECNQQFGACTPLQGQQANASQPYYIPPMTGFLLGYAASQLMSGGNRYYHIGGVSPLYRDYQGGRYLKPDGKQISTHSGTVYGRKAGDTALPARAVTVSRAGFGSSAAARGGFGRSSSSSSSSRSFGRGG</sequence>
</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD65002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24543.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAC5</accession>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Feng T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24521.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="213" mass="23215" checksum="2F57AAEAC96FD5CE" modified="2016-02-17" version="1">MTDRPYSPSCDRNRDPILAVLRERFAGRREALEIGSGTGQHAVHFAAAMPWLRWQCSDAAAYLPGIRAWLDEAALPNTPPPLELQAVVGPAPGFAPAPPLPRGAAGDARGFDAVFSANTLHIMGWPQVEAFFAGLATVLAAQASVVVYGPFNYRGRYTSDSNRDFDGWLKARDPVSGIRDFEAVDELAAAIGLRLREDIAMPANNRCLVWRRD</sequence>
</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
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        <text evidence="1">Belongs to the DinB family.</text>
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        <source>
            <dbReference type="ARBA" id="ARBA00008635"/>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="184" mass="20530" checksum="80A0C8F93677FACE" modified="2016-02-17" version="1">MNLLAHARLMADYNRWMNQRVYAAAARLPAEAVAQDRGAFFGSILGTLNHLLTADRIWLRRFAEHPARYAALESLRAQPAPTDLRAIAHDTLPALRAAREELDARIEDWIGETAEADLDQALVYANTRGVVSRRRFGLLLLHFFNHQTHHRGQVTTLLTQAGEDVGGTDLLELIPTLMADVDGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAF5</accession>
    <name>A0A0S2DAF5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_24735</name>
        <name evidence="3" type="ORF">FE772_01650</name>
        <name evidence="1" type="ORF">GLE_0150</name>
    </gene>
    <organism evidence="1 4">
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        <lineage>
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        </lineage>
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    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000098">
        <property type="protein sequence ID" value="OPD61231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945832.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000098.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55509">
        <property type="protein sequence ID" value="ALN55509"/>
        <property type="gene ID" value="GLE_0150"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61231">
        <property type="protein sequence ID" value="OPD61231"/>
        <property type="gene ID" value="BV903_24735"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0150"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.152"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD61231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="126" mass="13752" checksum="DDE4530C3CDBE52A" modified="2016-02-17" version="1">MTQLPFADAESSPFQGWRRVFVAGAQVAPRFLDERGAYRYGLFELAAASVAELERELVQADPSSALNFAVIDTTAADWSPQRTGAFRQDLDFYLFTGATAQARDALREYLDANAPVAVLCMATPLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAP1</accession>
    <name>A0A0S2DAP1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Orotate phosphoribosyltransferase</fullName>
            <shortName evidence="4">OPRT</shortName>
            <shortName evidence="4">OPRTase</shortName>
            <ecNumber evidence="2 4">2.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">pyrE</name>
        <name evidence="7" type="ORF">BV903_12980</name>
        <name evidence="8" type="ORF">FE772_02105</name>
        <name evidence="6" type="ORF">GLE_0257</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">C3</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate</text>
            <dbReference type="Rhea" id="RHEA:10380"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.10" evidence="2 4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000032">
        <property type="protein sequence ID" value="OPD63533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945907.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0257"/>
    <dbReference type="EnsemblBacteria" id="ALN55616">
        <property type="protein sequence ID" value="ALN55616"/>
        <property type="gene ID" value="GLE_0257"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63533">
        <property type="protein sequence ID" value="OPD63533"/>
        <property type="gene ID" value="BV903_12980"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0257"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.258"/>
    <dbReference type="OMA" id="MKAYQRQ"/>
    <dbReference type="OrthoDB" id="1280396at2"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00119"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004588">
        <property type="term" value="F:orotate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01208">
        <property type="entry name" value="PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023031">
        <property type="entry name" value="OPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004467">
        <property type="entry name" value="Or_phspho_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00336">
        <property type="entry name" value="pyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 4" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="5">
        <location>
            <begin position="42"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Orotate binding" evidence="4">
        <location>
            <begin position="34"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-phosphoribose 1-diphosphate binding" evidence="4">
        <location>
            <begin position="72"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-phosphoribose 1-diphosphate binding" evidence="4">
        <location>
            <begin position="124"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>orotate</name>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>orotate</name>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN55616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD63533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW24648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="218" mass="22852" checksum="C7E21159A11D2472" modified="2016-02-17" version="1">MTDHRTRFLQLALKADALRFGEFTLKSGRVSPYFFNAGRFDSGAALAGLAGCYADAIAAAGLDFDLLFGPAYKGIPLATALGCEYAGRGRDLPLAFNRKEAKAHGEGGMLIGAPLAGRRVLIVDDVITAGTAIREALGLIRDAGGTVAGIVIALDRQEAVDPAQSRRSAAETVAIEHGLPVIAIATLDDLLAFTGASAEFSAQRERLLAYRAAYGREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBE5</accession>
    <name>A0A0S2DBE5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946070.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55843">
        <property type="protein sequence ID" value="ALN55843"/>
        <property type="gene ID" value="GLE_0485"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0485"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.481"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595257" evidence="1">
        <location>
            <begin position="23"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="196" mass="19366" checksum="0DC4486B3BB96569" modified="2016-02-17" version="1">MKIQTQTLYGALLAVAFAPALAQNAASPAELTQAATGPAFTVGSTEFRLAPSAVVRPADASAAGAGIGLPTAGYTVDLPAKATAARAQAQSTSNPGGLVAAAPAGGGENLAVAVSASGGTVIVKPELDVYITHIGVVDALVKDSGGTLLYSSDIGGKATIGFGSVDQAMAARERILGRAGVKDVAPVLLEQRQVAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBG3</accession>
    <name>A0A0S2DBG3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_15175</name>
        <name evidence="4" type="ORF">FE772_03240</name>
        <name evidence="2" type="ORF">GLE_0500</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000040">
        <property type="protein sequence ID" value="OPD62986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946081.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55858">
        <property type="protein sequence ID" value="ALN55858"/>
        <property type="gene ID" value="GLE_0500"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62986">
        <property type="protein sequence ID" value="OPD62986"/>
        <property type="gene ID" value="BV903_15175"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0500"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.495"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595263" evidence="1">
        <location>
            <begin position="25"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="72" mass="7782" checksum="B2E68FE5B5EBC8C9" modified="2016-02-17" version="1">MKRNAIGWTALAMLMFGMGFGASATVPDPQECLDSCNFWFDQCLLEGDPSKTCAKENVACIRTCLLLSSQGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBI2</accession>
    <name>A0A0S2DBI2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_03375</name>
        <name evidence="2" type="ORF">GLE_0532</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946102.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55890">
        <property type="protein sequence ID" value="ALN55890"/>
        <property type="gene ID" value="GLE_0532"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0532"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.526"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242157" evidence="1">
        <location>
            <begin position="24"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="244" mass="26111" checksum="3A51F949163A1486" modified="2016-02-17" version="1">MHRLSSLALAGLLCAGPALPAVAAGGNDFCDGIVEVPLRTRSGNDYAGGRCQVDLLHDRPSPLDPAGGVRLHDLQWDTLRRPPATAATPVRLEVDVGPQNFVDGEALIEWTFESSKTGELRLLVLSLWRSDDSKDAGAGPTRVLAQLYAPGRPDWSLAGPSDDLGETQALAVADLSPKPSLSRFVLVFDGRQATVSVEGGGTHSFPMPHAGWTLVHLRNGVLARKPWQAGEGLILWWPVWLAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBK8</accession>
    <name>A0A0S2DBK8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0524</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946095.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0524"/>
    <dbReference type="EnsemblBacteria" id="ALN55882">
        <property type="protein sequence ID" value="ALN55882"/>
        <property type="gene ID" value="GLE_0524"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0524"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.519"/>
    <dbReference type="OMA" id="PVRFHFI"/>
    <dbReference type="OrthoDB" id="1625042at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021549">
        <property type="entry name" value="DUF2894"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11445">
        <property type="entry name" value="DUF2894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="248" mass="26571" checksum="F469A9186FF421B2" modified="2016-02-17" version="1">MNSVPASADAADPRTTLEAWRARGYDRCDRAGFARIDALERRAAAQDGELRRVLDARVRELIGIYAGALERRQAQASETAAREAGAQASAVDAATAAAAPAKRAARKGAKRKSGTSAETAAPAPTLIELTQRLQAAAATREAGDGDAPRAAFPQLAALDEFRMRFSRLRMDRQLRESLEPSSTDAGPLNSGRLVHRALSTMQALAPEYLQQFMAYVDALAWMERLGAGVGEAEEPAAAAGKRGRKRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBP9</accession>
    <name>A0A0S2DBP9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MFS transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Transporter, major facilitator family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_03465</name>
        <name evidence="2" type="ORF">GLE_0547</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946116.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0547"/>
    <dbReference type="EnsemblBacteria" id="ALN55905">
        <property type="protein sequence ID" value="ALN55905"/>
        <property type="gene ID" value="GLE_0547"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0547"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.541"/>
    <dbReference type="OMA" id="LWQMMLL"/>
    <dbReference type="OrthoDB" id="498436at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="307"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="348"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="395"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="455" mass="47239" checksum="8B06F9669A4ACE7E" modified="2016-02-17" version="1">MSRWSGLRDFLLIWFGQLVSGVGSRLTTFALGVWVLQTTGSTTRFALVFVSMAVPALLISPFAGALVDRWDRRRTMIVCEAISAATMLALAGLLASGHLAMWHIYAGVGAVALSNAFLQPAYAASIPLLASADQLTRVNGLVQTGFAVAQVGGPLLAGVLVSTISLQGVLVVDALTFVIGLLALCLAKVPRLARDPQAPQQGLWQEASTGFAYVRERRGLMGLLIVFGLSNFMFGIASIAITPLILSVADPALLGVQMAIGGSGLLFGGLLMSTWGGPRRRVVGVLGFSMLAGLFLAAHGLRPSFPLLVVAGFAFFLSVPVINACNATLWQSKVPAELQGRCFAIQRVLAESAMPLAFCLAGPLAEHVFEPLMAADGALAGSLGLLIGVGPGRGLGLMFLVLGAAMMTIAAVAWSRRAIREVENDLPDALAAPAVAHADSEAPAGAAQGDARCAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBU9</accession>
    <name>A0A0S2DBU9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Type VI secretion system Vgr family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_0442</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VgrG protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0442"/>
    <dbReference type="EnsemblBacteria" id="ALN55800">
        <property type="protein sequence ID" value="ALN55800"/>
        <property type="gene ID" value="GLE_0442"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0442"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.439"/>
    <dbReference type="OMA" id="DSWGAIR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006531">
        <property type="entry name" value="Gp5/Vgr_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028244">
        <property type="entry name" value="T6SS_Rhs_Vgr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017847">
        <property type="entry name" value="T6SS_RhsGE_Vgr_subset"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006533">
        <property type="entry name" value="T6SS_Vgr_RhsGE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037026">
        <property type="entry name" value="Vgr_OB-fold_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018769">
        <property type="entry name" value="VgrG2_C_DUF2345"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10106">
        <property type="entry name" value="DUF2345"/>
        <property type="match status" value="1"/>
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</entry>
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            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
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    <accession>A0A0S2DCS9</accession>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 20">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the pyruvate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="4 12"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000030">
        <property type="protein sequence ID" value="OPD63636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946438.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000030.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0983"/>
    <dbReference type="EnsemblBacteria" id="ALN56341">
        <property type="protein sequence ID" value="ALN56341"/>
        <property type="gene ID" value="GLE_0983"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63636">
        <property type="protein sequence ID" value="OPD63636"/>
        <property type="gene ID" value="BV903_12495"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0983"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.971"/>
    <dbReference type="OMA" id="QVPIVQK"/>
    <dbReference type="OrthoDB" id="1098983at2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018209">
        <property type="entry name" value="Pyrv_Knase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PTHR11817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="SSF50800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="SSF52935"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00110">
        <property type="entry name" value="PYRUVATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 12" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 12 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 15" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PK" evidence="13">
        <location>
            <begin position="6"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="PK_C" evidence="14">
        <location>
            <begin position="360"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ALN56341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="OPD63636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="QCW25196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="488" mass="51943" checksum="14C2A258A65BD40D" modified="2016-02-17" version="1">MSHSPRRTKILATLGPATDPPGVLDALLKAGVDVVRLNFSHGDPSSQVARAEAVREAAQRVGVEVGILADLPGPKIRIERFAEGRVLLKAGDRFDLIAKDNPPPGNLREVGVSYLGLPGDVAPGDVLLLDDGLLQLRVGAVEGERIVTTVLNDGALSDRKGLNKLGGGLSLGALTERDKELIGVAAQIGVDFIAVSFCRNAQDMNDARAIARAAGSEAALVSKIERAEAIENLAEIVEASDVVMVARGDLGVEIGDAELPGLQKKIIRESLARNRVVITATQMLQSMVDNPIPTRAEVLDVANAVIDGTDAVMLSQESAAGRYPVKAVEAMSRICLGAERQFDHDTDFEAAPRNLQRADQAIAMAAMFLSEHIGVRAIVAMTESGGTVRFLSRFRSNAPIYAFSRHAGARRQMALMRDVYPIDFDSRGMASRDAARNVVKQLFDAGMLEAGERMIFTSGDTMEQHGATNTLRLLQVGDGGSAEGLGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD11</accession>
    <name>A0A0S2DD11_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1076</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56434">
        <property type="protein sequence ID" value="ALN56434"/>
        <property type="gene ID" value="GLE_1076"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1076"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="49" mass="5611" checksum="E3FEB0FB47AAE29F" modified="2016-02-17" version="1">MRTHAARWHRSIVVERGATGDDGDAARATALCRRQRRARECHLVFAFEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDA5</accession>
    <name>A0A0S2DDA5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1007</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56365">
        <property type="protein sequence ID" value="ALN56365"/>
        <property type="gene ID" value="GLE_1007"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1007"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.995"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="56" mass="6392" checksum="1EFE993B3579C90E" modified="2016-02-17" version="1">MNAERQGLKIRDTARAIAARSGQVRCRWSRFGPCGRAFRPDALVPDHRDRTGKRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDL6</accession>
    <name>A0A0S2DDL6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Phosphoribosylformylglycinamidine cyclo-ligase</fullName>
            <ecNumber evidence="3 12">6.3.3.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 12">AIR synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11 12">AIRS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 12">Phosphoribosyl-aminoimidazole synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12 15" type="primary">purM</name>
        <name evidence="15" type="ORF">GLE_1220</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 12">
            <text>2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ATP = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:23032"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="ChEBI" id="CHEBI:147287"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 12">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the AIR synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.1" evidence="3 12"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1220"/>
    <dbReference type="EnsemblBacteria" id="ALN56577">
        <property type="protein sequence ID" value="ALN56577"/>
        <property type="gene ID" value="GLE_1220"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1220"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1205"/>
    <dbReference type="OMA" id="EPLFMTD"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00129"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004641">
        <property type="term" value="F:phosphoribosylformylglycinamidine cyclo-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02196">
        <property type="entry name" value="PurM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00741">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004733">
        <property type="entry name" value="PurM_cligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10520">
        <property type="entry name" value="PTHR10520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00878">
        <property type="entry name" value="purM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRS" evidence="13">
        <location>
            <begin position="67"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="14">
        <location>
            <begin position="183"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ALN56577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="354" mass="37665" checksum="B03BEE5D43A330CD" modified="2016-02-17" version="1">MTASSSDTSPKPLTYRDAGVDIDAGNEVVERIKPLVKRSFRPEVMGGLGGFGALFDLSGKYREPVLVSGTDGVGTKLKLAQQLNRHDTIGIDLVGMCVNDVLVQGAEPLFFLDYFATGKLDVDTTVAVVGGIARGCELAGCALIGGETAEMPDMYPPGEYDLAGFTVGAVEKSQILDGSRVRRGDVLIGIASSGPHSNGYSLIRRIFDRAGRPGDVAVGGVRLIDALMEPTALYVKPVLELLRGNGGEHTIHAMAHITGGGLTENIIRVIPDGLGLDIRTATWTLPPVFDWLQREGAVPREEMWRTFNCGIGFVLVVPDEAAAATEADLRRLGLAHWRIGEVVGHSGGERVHIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDY0</accession>
    <name>A0A0S2DDY0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1357</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946714.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56714">
        <property type="protein sequence ID" value="ALN56714"/>
        <property type="gene ID" value="GLE_1357"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1357"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1339"/>
    <dbReference type="OMA" id="LFEYQHA"/>
    <dbReference type="OrthoDB" id="1056910at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045929">
        <property type="entry name" value="DUF6348"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19875">
        <property type="entry name" value="DUF6348"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="297" mass="32287" checksum="5B47E386624AF0FF" modified="2016-02-17" version="1">MSASAAGPEFGLLDANPGGSPAGHLRFEDEAGETYLEPFDLVETLAAVLVENGQRAHAYDNGWIEIGDDGLFAFPQLVDFTELDGGTIRTASTIQCNHPRLFPQGLFEYQHATGETFDDSVKRGFDQWARTDLLALLDATRAEPETCMTMRMEFGGEDGAPRRERRIVFGPVASFGRAQQAEAEAARAAACAADGEPADACEAGDDGDAHGFCPCCLFTNSLEAFRPLLEQPGLFALRLFASRDHQDGECQADCRVNGEDWPQGLDGLRDYAANWPSAPGQTIEFRKQYVIVQDAPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE33</accession>
    <name>A0A0S2DE33_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aminopeptidase N</fullName>
            <ecNumber evidence="4">3.4.11.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLE_1405</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.</text>
            <dbReference type="EC" id="3.4.11.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M1 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.2" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1405"/>
    <dbReference type="EnsemblBacteria" id="ALN56762">
        <property type="protein sequence ID" value="ALN56762"/>
        <property type="gene ID" value="GLE_1405"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1405"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1385"/>
    <dbReference type="OMA" id="AASWFPC"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="SSF63737"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594752" description="Aminopeptidase N" evidence="11">
        <location>
            <begin position="34"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M1_N" evidence="13">
        <location>
            <begin position="50"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M1" evidence="12">
        <location>
            <begin position="297"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN56762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="469" mass="52255" checksum="064BDBBB503DCA78" modified="2016-02-17" version="1">MPAATTPHRPSRLRARLAAALAAAALAAPIAAAAQGAAAARAGANLDVLHYTARVEPDIAGKTLRGQVSIRLALRAEGAQQLEFDAGELEIEKVSERGRALVFEKVEQRLRVRLPQPGKSGERHEIDVVYRGAPRYGLEFHPERSEVYTIFSTSQWLVCIDAPSERASLDLTLTVPSGLKAVGNGRLVSKSALGGRRDSYRWRQDQPMPSYVYGFAAGRYNEAGGTGENGELRFLSAELEGPQLRKLFGDSADMLRFFGRRAGIRYRGTYSQVLVAKTVGQELDGFALLSEAYGREVLEKPEAQGLIAHELAHQWWGNMVTNRDWGQFWLNEGFANFMAAAYLEHRFGEAAYRERVDSWKRRLDKLRESGKDHALVYANWNKPTADDRAVVYQKGAYVLHLLREELGERAFWRGVRTYTRAYYGHSVTSADLRQVMERASGRDLSAFFARWVDGAEPAPAMPSRLDPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE58</accession>
    <name>A0A0S2DE58_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56632">
        <property type="protein sequence ID" value="ALN56632"/>
        <property type="gene ID" value="GLE_1275"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1275"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1258"/>
    <dbReference type="OMA" id="CHRSADP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="176" mass="19746" checksum="5AD7F37003FFE787" modified="2016-02-17" version="1">MRLLIPALLALTFVGCSCQRNVDDNGGDGTAPPAQAQTPETTAAPSAAQLRAQALEQRRNDAYTDAVGTLHLYLQRVGAGDQDAADKFWGYQRMPRGNEESNLRALRNLRGLRIQNQTPEPLDQEPVPELLRIPVDLRATLENGENRRYTGWYRLRRNQVEQRWELTGVLVAAKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE63</accession>
    <name>A0A0S2DE63_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1298</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56655">
        <property type="protein sequence ID" value="ALN56655"/>
        <property type="gene ID" value="GLE_1298"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1298"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1281"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="50" mass="5538" checksum="5FF2D69653B423A9" modified="2016-02-17" version="1">MPRRTRSSRPAVFYGRRGRADPPGCVLNLTGAFSCQINTGFVHCTKTVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEP2</accession>
    <name>A0A0S2DEP2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase, S41 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">S41 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_09035</name>
        <name evidence="3" type="ORF">GLE_1755</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947027.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57110">
        <property type="protein sequence ID" value="ALN57110"/>
        <property type="gene ID" value="GLE_1755"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1755"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1731"/>
    <dbReference type="OrthoDB" id="1646508at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242556" evidence="1">
        <location>
            <begin position="25"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="TSPc" evidence="2">
        <location>
            <begin position="117"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="332" mass="35255" checksum="523D995C56B97089" modified="2016-02-17" version="1">MIVDKAPLLALALAAMCLPLDSLAAPPDRESLPDFVCGALEKIYFDPVKAKALCKAARETGKSPEFVQAAPADQARQLTQALRNRSHDKHFYVGIPKPAGTVAAVPPTATATAPAPAPALPADANGGWVEVRILPGQIGYVKWTQHVADDAAFAKITAALQFLSGVKALVFDISRDGGGDGRANGFVYQHLFQDEAYQGLLQKKCKGETAWKNGEVPYHYSPAPKFYQTPVYILVSEKTGSAAEYFALIGQDSGRATVLGTTTAGAGNPVAQIATDDYFAYIPNCEIRTRSGRSIEGVGVVPDVVLKSDDRVQEALAFVRQDLARKSAAGAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEQ4</accession>
    <name>A0A0S2DEQ4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glutaredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">grxC</name>
        <name evidence="5" type="ORF">GLE_1652</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glutaredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946947.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1652"/>
    <dbReference type="EnsemblBacteria" id="ALN57009">
        <property type="protein sequence ID" value="ALN57009"/>
        <property type="gene ID" value="GLE_1652"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1652"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1631"/>
    <dbReference type="OMA" id="GRTTFPQ"/>
    <dbReference type="OrthoDB" id="2045232at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097573">
        <property type="term" value="F:glutathione oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03418">
        <property type="entry name" value="GRX_GRXb_1_3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011767">
        <property type="entry name" value="GLR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014025">
        <property type="entry name" value="Glutaredoxin_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011900">
        <property type="entry name" value="GRX_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00160">
        <property type="entry name" value="GLUTAREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02181">
        <property type="entry name" value="GRX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00195">
        <property type="entry name" value="GLUTAREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2 3" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="4">
        <location>
            <begin position="13"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="95" mass="10266" checksum="3D29A55DD052516E" modified="2016-02-17" version="1">MSDTASQTPAPAIVIYTTAICPYCVAAKNFLKSKGQTWSEVRIDLDPAEREKMIARTRRTSVPQIFVGETHVGGYDDMMALHRAGGLEPLLAGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DER2</accession>
    <name>A0A0S2DER2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyl transferase, group 1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_1637</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1637"/>
    <dbReference type="EnsemblBacteria" id="ALN56994">
        <property type="protein sequence ID" value="ALN56994"/>
        <property type="gene ID" value="GLE_1637"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1637"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1617"/>
    <dbReference type="OMA" id="FHTNFPQ"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="3">
        <location>
            <begin position="14"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="2">
        <location>
            <begin position="192"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="398" mass="43408" checksum="37868C94FA143AAE" modified="2016-02-17" version="1">MRYAIVTETYPPEINGVALTVQGLERGLRARGHEVALVRPRQIADGTGDGADHELLVRGLPLPRYPGLRFGLPCAARLRRDWTARRPDAIYVATEGPLGGSALKAARKLGIPAATGFHTRFDEYMRDYGAPFLVGAALAWMRRFHNGADATLVPTRELAEFLRARGFEDVVRLPRAVDTALFDPTRRMPSLREAWGAPGDALVAIYVGRIAPEKNLDLAVRAFRSLQQRRPQARFVWVGDGPSREKLQRDNPDFVFCGVQRGETLAAHFASGDLFLFPSLSETFGNVTLEAMASGVPTVAFDYGAAHEHLRDGEHGAAVSNGDDAGFIDAAVRIATDDALRARMARAGREAVGGLRPQQVAADFDAVLHGLAERNARGTPKRPPHDARSDNKPEQEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DER8</accession>
    <name>A0A0S2DER8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1706</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57061">
        <property type="protein sequence ID" value="ALN57061"/>
        <property type="gene ID" value="GLE_1706"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1706"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1684"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="51" mass="4764" checksum="62151A8ABB978100" modified="2016-02-17" version="1">MRRAGVAAARTRTGGAGAVGGAGTDRTPAASRRASSHPPPGLAGPGGQGDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DES8</accession>
    <name>A0A0S2DES8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">GTP 3',8-cyclase</fullName>
            <ecNumber evidence="3 12">4.1.99.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Molybdenum cofactor biosynthesis protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12 14" type="primary">moaA</name>
        <name evidence="15" type="ORF">FE772_08645</name>
        <name evidence="14" type="ORF">GLE_1668</name>
    </gene>
    <organism evidence="14 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">C3</strain>
        </source>
    </reference>
    <reference evidence="15 17" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>AH2 + GTP + S-adenosyl-L-methionine = (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-deoxyadenosine + A + H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:49576"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.1.99.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Monomer and homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the radical SAM superfamily. MoaA family.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.22" evidence="3 12"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946961.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1668"/>
    <dbReference type="EnsemblBacteria" id="ALN57025">
        <property type="protein sequence ID" value="ALN57025"/>
        <property type="gene ID" value="GLE_1668"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1668"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1647"/>
    <dbReference type="OMA" id="DYLRMSV"/>
    <dbReference type="OrthoDB" id="1199289at2"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019008">
        <property type="term" value="C:molybdopterin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061798">
        <property type="term" value="F:GTP 3',8'-cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01225_B">
        <property type="entry name" value="MoaA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013483">
        <property type="entry name" value="MoaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000385">
        <property type="entry name" value="MoaA_NifB_PqqE_Fe-S-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010505">
        <property type="entry name" value="Mob_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06463">
        <property type="entry name" value="Mob_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02666">
        <property type="entry name" value="moaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01305">
        <property type="entry name" value="MOAA_NIFB_PQQE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9 12" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7 12" id="KW-0408">Iron</keyword>
    <keyword evidence="8 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 12" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="13">
        <location>
            <begin position="19"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-substrate</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-substrate</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="277"/>
            <end position="279"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-substrate</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN57025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW25726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="346" mass="37947" checksum="0BDD22F5C42D0735" modified="2016-02-17" version="1">MNAAADRLVPLAAPDPLDRRGRPLRDLRLSVIEACNFRCPYCMPAERVPDDYGLDAASRLSFDEIETLVRGFVRVGVRKLRLTGGEPLLRKNLPELIARLSRIDGLDDLALTSNGSLLARQARALREAGLRRLTVSLDALDPDLFRRLSGGRGEVAQVLAGIEAARAAGFGPLKINCVVQRGVNEDQVLPLAERFRGSGDVLRFIEYMDVGNCNGWDARGVVSTRQLRDAIDARWPLRALDAQYRGEVASRYAYRDGAGEIGFVSSISAPFCGDCHRARVSADGRLYTCLFAAEGSDLREALAGGETALAERVAALWRGRNDRYSELRAADAPRPKRHVEMFLIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF16</accession>
    <name>A0A0S2DF16_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_08475</name>
        <name evidence="2" type="ORF">GLE_1633</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56990">
        <property type="protein sequence ID" value="ALN56990"/>
        <property type="gene ID" value="GLE_1633"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1633"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1613"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="59" mass="5988" checksum="295E67CD70D46B81" modified="2016-02-17" version="1">MNEKGASAAKEGDAKQGEATDGKAMDGDDGGGSRGPAAVFLRTTRPPPRPARAFTKMPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFB3</accession>
    <name>A0A0S2DFB3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="3">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_09085</name>
        <name evidence="7" type="ORF">GLE_1765</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947036.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1765"/>
    <dbReference type="EnsemblBacteria" id="ALN57120">
        <property type="protein sequence ID" value="ALN57120"/>
        <property type="gene ID" value="GLE_1765"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1765"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1741"/>
    <dbReference type="OMA" id="DAWKVYM"/>
    <dbReference type="OrthoDB" id="744602at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043878">
        <property type="term" value="F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044638">
        <property type="entry name" value="ALDH7A1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43521">
        <property type="entry name" value="PTHR43521"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="6">
        <location>
            <begin position="28"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW25798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="510" mass="54229" checksum="7345DA6E70A93B33" modified="2016-02-17" version="1">MTHPVLAALGLKDNESGTYLGHGEWSKTADAGVLEPVNPTDGEVLARVQASSQSDYDTIVERAQAAFAVWRTTPAPRRGEAIRLCSDALRKHKDALGSLVALEMGKSKPEGDGEVQEMIDIGDFAVGLSRQLYGLTMHSERPGHRMYEQWHPLGIVGIISAFNFPVAVWAWNSFIAAICGDISIWKPSPKTPLSAIASMKICNEALRAGGFPDLFFLFNDAGTELASNFVDDKRIGLVSFTGSTKVGRAVGERVARRMGRSLLELGGNNAIIVDASADLKLAIPAIAFGAVGTAGQRCTTTRRLFVHESIHDDVLAKLVAAYKQVEKKIGDPTDPANLMGPLNSQDGVQAYLDAIAKAKASGGKVETGGERIDRKGNFVLPAIVTGLTNDAEVVQTETFAPILYVMKFSRLEDAIALQNDVPQGLSSSIFTANLKAAEAFLSAAGSDCGIANVNIGTSGAEIGGAFGGEKETGGGRESGSDAWRAYMRRQTNTINYSDALPLAQGIKFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFC4</accession>
    <name>A0A0S2DFC4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1934</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57285">
        <property type="protein sequence ID" value="ALN57285"/>
        <property type="gene ID" value="GLE_1934"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1934"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1899"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="80" mass="8339" checksum="DA967528CDB5ABE7" modified="2016-02-17" version="1">MKKASKKVAKKAAKKAVKKTAKKAAKKTAKKAAKKAAKKAVKKSAKKAVKKTAKKAAKKFAKKVAKKADVGTGYTGPSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFF4</accession>
    <name>A0A0S2DFF4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Thymidylate kinase</fullName>
            <ecNumber evidence="3 6">2.7.4.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 6">dTMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">tmk</name>
        <name evidence="9" type="ORF">BV903_07305</name>
        <name evidence="8" type="ORF">GLE_1697</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">B25</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + dTMP = ADP + dTDP</text>
            <dbReference type="Rhea" id="RHEA:13517"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58369"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the thymidylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="3 6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000013">
        <property type="protein sequence ID" value="OPD64684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946985.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1697"/>
    <dbReference type="EnsemblBacteria" id="ALN57053">
        <property type="protein sequence ID" value="ALN57053"/>
        <property type="gene ID" value="GLE_1697"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64684">
        <property type="protein sequence ID" value="OPD64684"/>
        <property type="gene ID" value="BV903_07305"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1697"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1675"/>
    <dbReference type="OMA" id="VMTREPG"/>
    <dbReference type="OrthoDB" id="1585072at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:thymidylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00165">
        <property type="entry name" value="Thymidylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate_kin" evidence="7">
        <location>
            <begin position="12"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="14"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN57053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD64684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="216" mass="23062" checksum="0598E51E5D65923A" modified="2016-02-17" version="1">MSLRTWPRLVTLEGGEGAGKSTVLAALRGAFEAAGIQAVYTREPGGTPLAEQIRGLMLDTQHEPATDETELLLAFAARAQHVRATVLPALQRGAWVVSDRFTDASYAYQGAGRGGDAAFIAELERRVVGIRPALTLLLDVPVDVGLARMRGRGAADRIESERNEFFERVRQGYRDRAAAEPARFEVIDAAQPAEAVAAQAVARLRALIAATAEGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFJ1</accession>
    <name>A0A0S2DFJ1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_10155</name>
        <name evidence="1" type="ORF">GLE_1998</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57348">
        <property type="protein sequence ID" value="ALN57348"/>
        <property type="gene ID" value="GLE_1998"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1998"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1965"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="64" mass="7019" checksum="AC064E8E97A89EC1" modified="2016-02-17" version="1">MRLDAFTELAADVLGAKLDPVYQGAHGLDHRRVYDATANGIFVRINTTPGTYRCVTVAHIYPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFM7</accession>
    <name>A0A0S2DFM7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">EAL domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">PAS domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">morA</name>
        <name evidence="6" type="ORF">FE772_09905</name>
        <name evidence="5" type="ORF">GLE_1947</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947163.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1947"/>
    <dbReference type="EnsemblBacteria" id="ALN57298">
        <property type="protein sequence ID" value="ALN57298"/>
        <property type="gene ID" value="GLE_1947"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1947"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1912"/>
    <dbReference type="OMA" id="IRHLANF"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13188">
        <property type="entry name" value="PAS_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="56"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="172"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="2">
        <location>
            <begin position="373"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="4">
        <location>
            <begin position="454"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="3">
        <location>
            <begin position="596"/>
            <end position="850"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW25933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="852" mass="94569" checksum="486EF4C51C5B01C9" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFW3</accession>
    <name>A0A0S2DFW3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Site-2 protease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_10770</name>
        <name evidence="2" type="ORF">GLE_2133</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947303.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57483">
        <property type="protein sequence ID" value="ALN57483"/>
        <property type="gene ID" value="GLE_2133"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2133"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2097"/>
    <dbReference type="OrthoDB" id="1536311at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="406" mass="44493" checksum="06E5BB708700A110" modified="2016-02-17" version="1">MDAAQPHDEAPPADAAAPAMRDLSPRAQRNWGRVALAWQTLGWVLLVLILLMVASQLSHGMAAAIVLVLVPAYLSAILVHESGHWIAARRCAMAVANVGIGPLELQPRRRGLRVRLRSRRGQQRDYGGWVLAYPDPRRDLRGDAIALAWGGCAANLAVAAVCAAVALLWQDAFGRTVALLLATMHGLVGALNLLPYPVGGHSPSDGLTLWRLRRNRYEDLPGASVKRFFGHLSMGLDPNDLPPELLRRMAAEDEPMPLLLDWLAFAIALDRNDEAAAGALRQRLRERVEACPQPLRESLADLLALCELHWAFHRALWHRGGAAAAELELLNPRARWLWPLPHLAPRVRGLAAALRGDAARARHWLERSRRYVENDPTPGLAAYEAGLRERVAALIDTPPTTGSQTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG85</accession>
    <name>A0A0S2DG85_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Integral membrane protein DUF6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947237.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57390">
        <property type="protein sequence ID" value="ALN57390"/>
        <property type="gene ID" value="GLE_2040"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2040"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2005"/>
    <dbReference type="OMA" id="MYVVVKV"/>
    <dbReference type="OrthoDB" id="1425840at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="274"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="24"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="160"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="297" mass="30385" checksum="6BAB8FCDC813F489" modified="2016-02-17" version="1">MNAILAPTGFAARLRLDALELPALAAIWGISFLFMRVAAPAFGPLALVELRLALGGLVLAPLLWRARAQFPLRLWPKLALIGAINSAVPFVLFAWGAERAPAGIGAITSAMTVLFAALVGFACFGEKIGTRRALALLGGFAGVGVLAAGKSGGAGAAIGWAVAAGCAAAFLYGVGLHLVRRHLGGLPPAAVASATLLSAALLMLPAALAQWPAQAIGARAWGAALLLGLLCTGLAYALFYRLVARIGAARTSLVTYLIPLFGVAWAWLLLDEPVTAPMAAAGALILAGVWLARREAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG93</accession>
    <name>A0A0S2DG93_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Efflux RND transporter periplasmic adaptor subunit</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Efflux transporter, RND family, MFP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_10670</name>
        <name evidence="3" type="ORF">GLE_2109</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947288.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2109"/>
    <dbReference type="EnsemblBacteria" id="ALN57459">
        <property type="protein sequence ID" value="ALN57459"/>
        <property type="gene ID" value="GLE_2109"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2109"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2073"/>
    <dbReference type="OMA" id="VGQVPTR"/>
    <dbReference type="OrthoDB" id="1432684at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="70"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="356" mass="37502" checksum="4A20E802F21818EC" modified="2016-02-17" version="1">MSATRSYLGIGIGLAVVGAVVWFGLAGRPQPAAAATIAAPVLTVSVVAAHKRAVDDAIAVVGATVPRENVVVVPELAGQQVREIHADVGDYVRKGQLLAVLDSSNLSIQSAGLRSEYERTRGEYERVQSLQPSGAVSREFVAQKNAAYQVALANLRNAELSVRRARIVAPTDGLIYERSAAIGGLTSFSEPLFKLAKDGLVEMEANVPERQVARLRVGLPASLRLAGESAPIQGEIRLIAPRVDSASRSASVRIALQRPGESAHRAAVGMFCEAGITVAQVEGWVLPGSALQQDAAGAFVWSVRSGNAVRRLPVEVVARTPEHVVVAAINAGERIVAKAGPFLRDGDIVALTQARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGA1</accession>
    <name>A0A0S2DGA1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_11025</name>
        <name evidence="4" type="ORF">FE772_10170</name>
        <name evidence="2" type="ORF">GLE_2002</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000025">
        <property type="protein sequence ID" value="OPD63928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947202.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2002"/>
    <dbReference type="EnsemblBacteria" id="ALN57352">
        <property type="protein sequence ID" value="ALN57352"/>
        <property type="gene ID" value="GLE_2002"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63928">
        <property type="protein sequence ID" value="OPD63928"/>
        <property type="gene ID" value="BV903_11025"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2002"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1969"/>
    <dbReference type="OrthoDB" id="1536690at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595121" evidence="1">
        <location>
            <begin position="22"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="464" mass="47713" checksum="F6F3DA774C37A84C" modified="2016-02-17" version="1">MIRKNLLSLALLAGLSGLAFAAAADEMGAEPVTAAPLAKAFGAVDFATSGKAGTVRSVDLGLPSQASVTALGQLRIEQGRHGQPLQVGLARNVGRSRIDLGGLNWETLPDGSRGARFSLTSTHAVALRAGLQLRATGKADAGAVTLRFAGNDGRVFAEDGRAFAQAGTGWSPVVAGDTLTVEIVLAPGQRADDFSLRVPQLSHLDVDPAASSRDLAKATGVGASQACEQDIVCRVNPSAGFLAASKAVARMVYTSGGSSYLCSGTLLNNSNSPKRQLFWTAAHCISTQAEADSLQTYWFFDATACNNDTASASAVTLSGGAYLRHANTTRDTALLELKSAPPAGAYYAAWNSAALTATGASIEGIHHPAGDLKKYSLGSVTSLSTSLDGRSPLTQVKWSAGVTEGGSSGSGLFTVAGNGDYQLRGGLYGGYSACKKKGQLGPNQPDAYSRLDGVWSSVSSYFSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGC1</accession>
    <name>A0A0S2DGC1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_10320</name>
        <name evidence="2" type="ORF">GLE_2034</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947231.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57384">
        <property type="protein sequence ID" value="ALN57384"/>
        <property type="gene ID" value="GLE_2034"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2034"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1999"/>
    <dbReference type="OrthoDB" id="1478794at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242198" evidence="1">
        <location>
            <begin position="21"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="310" mass="34544" checksum="8E61ED9E4150D0B0" modified="2016-02-17" version="1">MRMKRIVVACCLAAACAACSDRDAGPGRSATAAPPPAAAAATPLPPQAREYRSDHYAIFSAATPAQTVRVATAVEALYRAYGEFFALPPAPADTRLRLILYRDRAQFSAFNTSMPWAEAYYRTPYCHAYFDQDSDSPYHWMLHEATHQLHAERAGYARAKWINEGVASYFGASRFDGARLRPGTIDPGAYPIWWLPDLALSGSLERDLRSGLLIPLRQLIDNSGPPIGGRHLNVYYIEYWSLSHFLFHYDGGRYAAAYRRLLRGRGTLAEFERELGPVHAIQAQWYAYLLEKRAEVADGGALAEATPVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGL8</accession>
    <name>A0A0S2DGL8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">N-(5'-phosphoribosyl)anthranilate isomerase</fullName>
            <shortName evidence="4">PRAI</shortName>
            <ecNumber evidence="2 4">5.3.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">trpF</name>
        <name evidence="6" type="ORF">GLE_2146</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:21540"/>
            <dbReference type="ChEBI" id="CHEBI:18277"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="EC" id="5.3.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TrpF family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.24" evidence="2 4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2146"/>
    <dbReference type="EnsemblBacteria" id="ALN57496">
        <property type="protein sequence ID" value="ALN57496"/>
        <property type="gene ID" value="GLE_2146"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2146"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2110"/>
    <dbReference type="OMA" id="FYAKSPR"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00042"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004640">
        <property type="term" value="F:phosphoribosylanthranilate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00405">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00135">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001240">
        <property type="entry name" value="PRAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044643">
        <property type="entry name" value="TrpF_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42894">
        <property type="entry name" value="PTHR42894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00697">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="PRAI" evidence="5">
        <location>
            <begin position="13"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="220" mass="23777" checksum="C1D69D3F8EE178C5" modified="2016-02-17" version="1">MNPSRTLYRTRIKFCGFTRPGDVRLACELGADAIGFVFAAGSKRRVAPEEARAMRQALAPLVDAVALFADNPVDEVREVVRQVRPSLLQFHGNEDDAYCRGFGVPYLKAIAMGGELAGQHPSALLMRYPGAAGFLFDSHAEGGSGGSGKTFDWKRIPVGVQKPFILAGGITPDNVFEAILATLPWGVDVSSGIESAPGLKDGDRMRQFVEEVRRADCHVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGN6</accession>
    <name>A0A0S2DGN6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_11160</name>
        <name evidence="3" type="ORF">GLE_2216</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947370.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57565">
        <property type="protein sequence ID" value="ALN57565"/>
        <property type="gene ID" value="GLE_2216"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2216"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2178"/>
    <dbReference type="OMA" id="VQEMNRG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="344" mass="36733" checksum="4519B92BD9C6A0D1" modified="2016-02-17" version="1">MHADESPPELPLRLAAALVALASTGFMVWLLMRIPSPLPPAQELDVVLIERIAPAPRAVPESASVPEFESESQSESQSEPMPQRASPRSDASATDRAPATPARPAAANPSPAHAKAAPAARLYTAEGRPALAADPDFDPIKRKAYAPGSDEDPNAAKVRNAFERKNPLPSQGGGFDGWASDGTLGEALVESAQKRLQKIVDKLPGRKQVQEVVARPPPPVRFNPALHERPSDLGSEATGDAYKAAPIAFERAPGLGGQASARIRAAIGDLEQRRRGCDLERLRTLLAPALSGLDELQRIERAYASGADPVSAEQLLPRSADLAYDRARRAIWYADQRSADCAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGW8</accession>
    <name>A0A0S2DGW8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TonB C-terminal domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">TonB family C-terminal domain</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FE772_11690</name>
        <name evidence="6" type="ORF">GLE_2331</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947458.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2331"/>
    <dbReference type="EnsemblBacteria" id="ALN57680">
        <property type="protein sequence ID" value="ALN57680"/>
        <property type="gene ID" value="GLE_2331"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2331"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2295"/>
    <dbReference type="OMA" id="WQWANDM"/>
    <dbReference type="OrthoDB" id="1838053at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="39"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="50"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW26234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="221" mass="22906" checksum="65745168B5DDDA1A" modified="2016-02-17" version="1">MSETYGRGSKFSRALGVLGAIGVVAVMAWLVWSLMQGAGPTTKRQPPRITQVILPPPPPPPPPEPDKVQDEPKPVENTPFESIEPPKDDSAEPPGDPLTADAGPGSNEFGLQAGTGGGGTRIGGNGGGGNPYAGYAAMVQRTVQQYLQQGEKTRKGRYSATVAMWLNPDGTIQRSQVIAGTGKPELDAAIVAALQGRSLPQAPPAEMPQPINLRIGASSPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH09</accession>
    <name>A0A0S2DH09_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sphingosine-1-phosphate lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_2379</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the group II decarboxylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2379"/>
    <dbReference type="EnsemblBacteria" id="ALN57728">
        <property type="protein sequence ID" value="ALN57728"/>
        <property type="gene ID" value="GLE_2379"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2379"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2340"/>
    <dbReference type="OMA" id="DPHKMGL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016830">
        <property type="term" value="F:carbon-carbon lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="409" mass="44472" checksum="6DA736BAAE35A34C" modified="2016-02-17" version="1">MMPSLAVQGRKTLPARGQPWSELQQALSALRSADTDWRQGRASLDVYYAGEDVLDVARRAYAMFISENARAPHLFPSLQRMQEDLVQISLSLLGGGREAAGTVTCGSAESAMLAVCSAYRAFRARRPHVRRPHLLLPASAHPVYEQAAEIMGLDLIRVAIGGDYRASVETLGQCIEPETMMIVASAPSQPFGAIDPVEAIGRIARDRDVWLHVDACIGGFLAPHVARFVAGVPRFDLALPGVRSLSADLHTFGYAANGVSVLLHADPDDHAHQTFEYNQWPKGTWRSQTLSGTLAGGAVAAAWAVMHYLGETGYRALAQRVMHLRDRYIEGIERIGGLHVLGKPDLSVIAFGSDEFDIHAVGDAMQERGWQISRLASPAALHMTVTPVHDQGVEAYLEDLARCVAVARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH43</accession>
    <name>A0A0S2DH43_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA topoisomerase III</fullName>
            <ecNumber evidence="7">5.99.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">topB</name>
        <name evidence="7" type="ORF">GLE_2415</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type IB topoisomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.99.1.2" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947523.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2415"/>
    <dbReference type="EnsemblBacteria" id="ALN57764">
        <property type="protein sequence ID" value="ALN57764"/>
        <property type="gene ID" value="GLE_2415"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2415"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2377"/>
    <dbReference type="OMA" id="QYRYHPR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.66.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035447">
        <property type="entry name" value="DNA_topo_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001631">
        <property type="entry name" value="TopoI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014711">
        <property type="entry name" value="TopoI_cat_a-hlx-sub_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013500">
        <property type="entry name" value="TopoI_cat_euk"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01028">
        <property type="entry name" value="Topoisom_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00416">
        <property type="entry name" value="EUTPISMRASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55869">
        <property type="entry name" value="SSF55869"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Topoisom_I" evidence="6">
        <location>
            <begin position="96"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="349" mass="39574" checksum="1A44D0E4CF008D71" modified="2016-02-17" version="1">MASSPTSDRDPPATGLRYVDDDEPGFSRRRAGRGFAYRDARGRPVRAARQLERIRALAIPPAYTEVWICADPRGHLQATGRDARGRKQYRYHPRWRALRERGKFERIVAFAAALPALRRRVRADLALPGLPRSKVLAIVVAVMAHTLVRVGNDEYQRSNGSFGLTTLRKRHLQLLRGGRAQLAFRGKGGLRQQIELDDARLVRLVRRCRQLPGQALFQYLDEDGGRQAVGSGDVNEYLREAMGADFTAKDFRTWGATAAAFRRFASTELPPPRRDGRRNERAIARIENEAVAEVAQLLRNTPAICRKSYIHPAVLESWREGRLTLPARTPSSGRQWERAALAFLRKRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH64</accession>
    <name>A0A0S2DH64_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2582</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947654.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2582"/>
    <dbReference type="EnsemblBacteria" id="ALN57931">
        <property type="protein sequence ID" value="ALN57931"/>
        <property type="gene ID" value="GLE_2582"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2582"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2541"/>
    <dbReference type="OMA" id="FCAYLLP"/>
    <dbReference type="OrthoDB" id="1676663at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="179" mass="19007" checksum="820167CBE4B32B92" modified="2016-02-17" version="1">MTATTQIAEQMQLSEPGQALAAAHEAPLAAVSALIGAQRYGDALPLSLRLLPTPYALAWTCQCAGAQPLDERDAQGLRLAQRWMRERDEPSRQAAQAFAENDDYRSPGAWLAAAAAWASGAPAAEGGAPPAAHLTAVAANAALVLLASREPERFDERLQRWAEQAHALLGQVHPTEQIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHG6</accession>
    <name>A0A0S2DHG6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Linear gramicidin synthetase subunit C</fullName>
            <ecNumber evidence="12">5.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">lgr</name>
        <name evidence="12" type="ORF">GLE_2493</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.-" evidence="12"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947580.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2493"/>
    <dbReference type="EnsemblBacteria" id="ALN57842">
        <property type="protein sequence ID" value="ALN57842"/>
        <property type="gene ID" value="GLE_2493"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2493"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2456"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013217">
        <property type="entry name" value="Methyltransf_12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08242">
        <property type="entry name" value="Methyltransf_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 8" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="11">
        <location>
            <begin position="947"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="11">
        <location>
            <begin position="1988"/>
            <end position="2063"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="11">
        <location>
            <begin position="3051"/>
            <end position="3126"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="11">
        <location>
            <begin position="5460"/>
            <end position="5537"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="11">
        <location>
            <begin position="6183"/>
            <end position="6257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="856"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1603"/>
            <end position="1624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="5553"/>
            <end position="5575"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="2111"/>
            <end position="2138"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="8">
        <location>
            <position position="982"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="8">
        <location>
            <position position="2023"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="8">
        <location>
            <position position="3086"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="8">
        <location>
            <position position="5497"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="8">
        <location>
            <position position="6217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN57842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="6315" mass="671345" checksum="E1FE0CDB2511CAC6" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHH0</accession>
    <name>A0A0S2DHH0_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Polysaccharide biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2467</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_2467"/>
    <dbReference type="EnsemblBacteria" id="ALN57816">
        <property type="protein sequence ID" value="ALN57816"/>
        <property type="gene ID" value="GLE_2467"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2467"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2429"/>
    <dbReference type="OMA" id="AYMAIAR"/>
    <dbReference type="OrthoDB" id="564091at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="321"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="361"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="421"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="444"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="482" mass="50482" checksum="66B601D1358A3289" modified="2016-02-17" version="1">MLIRQTALYLPAQLLGPLAQLAAIVLWTHWLDPGEFGAFTLALAAQEAVYLLFLAFWSYYLLRFLPGADALARERMDTFEGWVLLANLALQAAALALVLRYLAGTPPGAAAFAVLFAFAFTRSYCTHLAERAKAGNDILAYTALQCGGPIGGLALGWLWAHLSRDGAARIGPLQVLGAYAIAQAASLLFALLRLPLRWRLWRVDRGLLRAVAAYGLPLALSGALAWVPGNGIRFVVEHGLGLAAVGLFAAGWTLGQRACAFAAMLVTAAAFPIALRLDASGERERALRQLADNGALLCAVLLPSAAGLIALSAPLSRLAVSAPYVADTLVILPIAALAGLVKNLRSHFANQAFLLARKTGWTLAIDALETALFLVGAALGLRALGLAGAAWGALAAVSVGAALSFFVAVRRLGMPLPAAHLARIVLASAAMSAALALLPPLAGWPALILATAFGGAVYAGALALCYRGHLRELRGRLPFLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHJ7</accession>
    <name>A0A0S2DHJ7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_12430</name>
        <name evidence="2" type="ORF">GLE_2488</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947576.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2488"/>
    <dbReference type="EnsemblBacteria" id="ALN57837">
        <property type="protein sequence ID" value="ALN57837"/>
        <property type="gene ID" value="GLE_2488"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2488"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2450"/>
    <dbReference type="OrthoDB" id="1948290at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
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        <property type="entry name" value="TylF_MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40036">
        <property type="entry name" value="PTHR40036"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="238" mass="27033" checksum="C04714EE55448AE7" modified="2016-02-17" version="1">MSRSAPTVDTGADDAPDAMPGPTSELARQRVFPEHRFQFSAHQLCFMCKCLSDTRNLAGAIVEIGCEYGHTTVFLNNYIDDLVGQDRPYYAIDTFSGFTESDVRFEADNRGKQGIAYQDFKENRKEWFERTLRINRIQRVRAIEADINAFDLPSLGPLSFVLLDVDLYRPTRKALPELYEMLLPGGVLVVDDCNPASNHWDGAYQAYIEFVRTRKITPRIMYNKLGVLRKPLPEAAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHL9</accession>
    <name>A0A0S2DHL9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallo-beta-lactamase L1 (Beta-lactamase type II) (Penicillinase)</fullName>
            <ecNumber evidence="3">3.5.2.6</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Subclass B3 metallo-beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">bla</name>
        <name evidence="4" type="ORF">FE772_13605</name>
        <name evidence="3" type="ORF">GLE_2717</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.2.6" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947762.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2717"/>
    <dbReference type="EnsemblBacteria" id="ALN58065">
        <property type="protein sequence ID" value="ALN58065"/>
        <property type="gene ID" value="GLE_2717"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2717"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2676"/>
    <dbReference type="OMA" id="IDTLHEP"/>
    <dbReference type="OrthoDB" id="733552at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008800">
        <property type="term" value="F:beta-lactamase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242669" evidence="1">
        <location>
            <begin position="24"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="2">
        <location>
            <begin position="66"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="311" mass="32288" checksum="9001A0EA67236B0D" modified="2016-02-17" version="1">MRLPAAVLAVSIASSLLAGCASAPQRGDAHAAATATIAPCPDKPKWGDPTAPRHIHGNTWYVGTCAISAILVTSEAGHILIDGAIDSAAPGIEANIRALGFDPAQVRYILNSHEHIDHAGGIARLARNTGARVVAREPAATALERGKGDRGDPQFLTVAPFAPVPSVQRIGDGDTVRLGTLALTAHATPGHTPGGTSWTWRSCDAAGQCRDIAYADSLTPFSDKVYRYSDDAAHPGALAAYRRGIETVAALPCEILLTPHPSASDMFQRMGPQASKPLVDTGACRAYAAGAAAKLDARLEQERAQPAPAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-06-17" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHN9</accession>
    <name>A0A0S2DHN9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2721</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58069">
        <property type="protein sequence ID" value="ALN58069"/>
        <property type="gene ID" value="GLE_2721"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2721"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2680"/>
    <dbReference type="OrthoDB" id="2069377at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595157" evidence="1">
        <location>
            <begin position="18"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="144" mass="14485" checksum="D45482573FCEDAC0" modified="2016-02-17" version="1">MAAGLGVCLGAPGAAWAADEAAAVGANVEAVVQGGRWSDAAGEGAGEGVYRVIVASQGFEHVSTGVRAQWKSDGGEDGLARIAHEAELVAPGHYSLGPPKLTRTAAGVRVELRGVATYDSRVKVVCRFELAAGGKVTVTKACGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHY8</accession>
    <name>A0A0S2DHY8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bacterial extracellular solute-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2781</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2781"/>
    <dbReference type="EnsemblBacteria" id="ALN58129">
        <property type="protein sequence ID" value="ALN58129"/>
        <property type="gene ID" value="GLE_2781"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2781"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2738"/>
    <dbReference type="OMA" id="WSRFTGY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="455"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="474" mass="52434" checksum="6F1D52452FDD1EAB" modified="2016-02-17" version="1">MGLSARAQRASAAERTAGAAGRGPARAARSVGGRWGRRIASLLMLASLVLLLGSCSGRGDGRTVVKFWAMGFEGEMVARLIPEFERQNPDIRVQVQQLPITSAHEKLLTAFAGDSLPDVCAIGNTWVSEFALLDALEPLDRRIAATPGLRAQDYFAGAWDTGVIDGRAYAVPWYVETRLPYYRRDLLEHAGIARPPQTWDEWKTAMAAIKREVGPDRYAVLFPLNEPEPLLNLGIQADEPLLRDGGRYGNFRSPGFKRALAFYREAFAQQWAPLASNTQIANVWNEFGRGYFSFYVNGPWNIAEFKRRLPADLQDKWMTMPLPGEHGPGASVAGGASFVLFRGSPRQDAAWKLIAYLSEPATQMRFHGLTGNLPPRRESWNAPALVGDPYARAFRDQLERARPAPKVPEWERIAMEIKLVGEQLANGRLTVDQAAAELDRRADRILEKRRWMLDQADQRAAKSASPAAAPGEGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI37</accession>
    <name>A0A0S2DI37_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2881</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2881"/>
    <dbReference type="EnsemblBacteria" id="ALN58229">
        <property type="protein sequence ID" value="ALN58229"/>
        <property type="gene ID" value="GLE_2881"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2881"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2843"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021279">
        <property type="entry name" value="DUF2721"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11026">
        <property type="entry name" value="DUF2721"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="160" mass="17806" checksum="CA0CFDFFE081892B" modified="2016-02-17" version="1">MPDPLQLSSHYAVVSAMITPAFFLTATASLLVSSNNRLARVVDRMRQQLATLEDTVDEHARQYLEARIILHRRRVRLILTCLQLLYGAMTAFVGTSLAIGIDQFADYRLRGVPTGLAMCGVLLVLAACINMGREARMSVSMLDAEVKREFDRDHGRGKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI65</accession>
    <name>A0A0S2DI65_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2848</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58196">
        <property type="protein sequence ID" value="ALN58196"/>
        <property type="gene ID" value="GLE_2848"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2848"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2807"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="89" mass="10017" checksum="6358629D7A96C056" modified="2016-02-17" version="1">MEHHVEWFQFTLPVDQTIGPEALRALWMRACGSTNVSVQRNSRTILGRRTPVYSLRASARLGGLAVIEARLRGLMQEARLNSKLTAVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIF3</accession>
    <name>A0A0S2DIF3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4180 domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Hydrolase, alpha/beta fold family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_14720</name>
        <name evidence="2" type="ORF">GLE_2954</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58302">
        <property type="protein sequence ID" value="ALN58302"/>
        <property type="gene ID" value="GLE_2954"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2954"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2916"/>
    <dbReference type="OMA" id="DAWITEC"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025438">
        <property type="entry name" value="DUF4180"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13788">
        <property type="entry name" value="DUF4180"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4180" evidence="1">
        <location>
            <begin position="21"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="133" mass="13906" checksum="4BBA71A0222A7D06" modified="2016-02-17" version="1">MNDANPAADDAPVFTVLPLGNERVLLCPADGAPIADARAATDLIGEASFAGATVLAIAAQRLDASFFRLASGLAGEIAQKAANYRLRLAVVGDIQAQLQRSSALRDWVRECGEGRTVLFVADLDELARRLGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIG9</accession>
    <name>A0A0S2DIG9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Redoxin/antioxidant, AhpC/TSA family</fullName>
            <ecNumber evidence="3">1.11.1.15</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Thioredoxin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_14855</name>
        <name evidence="3" type="ORF">GLE_2970</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.11.1.15" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58318">
        <property type="protein sequence ID" value="ALN58318"/>
        <property type="gene ID" value="GLE_2970"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2970"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2931"/>
    <dbReference type="OMA" id="EYVPAYY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242320" evidence="1">
        <location>
            <begin position="36"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="43"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="190" mass="21605" checksum="6EE57FE06DACDCD4" modified="2016-02-17" version="1">MCRTVFAQPPFAIKSLLLALSLCLGAVACTPGAQAEPVQPTARQPAPPAPDFQGIHRWINSPPLRMSQLRGKVVLVEFWTYACINCLHVQPHVNRWHARYRDQGLAVVGVHTPEYDYEHLTGNVRAAVERLGIDYPVAQDNDYATWNAYGNRFWPALYLIDRDGRIVYRHYGEGDYDKTEAMIRELLAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIT7</accession>
    <name>A0A0S2DIT7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BV903_09230</name>
        <name evidence="11" type="ORF">FE772_15950</name>
        <name evidence="9" type="ORF">GLE_3209</name>
    </gene>
    <organism evidence="9 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9 12">C3</strain>
        </source>
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        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">YC36</strain>
        </source>
    </reference>
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        </subcellularLocation>
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        <property type="molecule type" value="Genomic_DNA"/>
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            <dbReference type="EMBL" id="ALN58596.1"/>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <source>
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        <source>
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        <source>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <evidence type="ECO:0000256" key="1">
        <source>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <property type="protein sequence ID" value="ALN59264"/>
        <property type="gene ID" value="GLE_3922"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62339">
        <property type="protein sequence ID" value="OPD62339"/>
        <property type="gene ID" value="BV903_19145"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3922"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3859"/>
    <dbReference type="OMA" id="FWESTRD"/>
    <dbReference type="OrthoDB" id="1927539at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007621">
        <property type="entry name" value="TPM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04536">
        <property type="entry name" value="TPM_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="TPM_phosphatase" evidence="4">
        <location>
            <begin position="19"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD62339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="161" mass="17242" checksum="E2CFB1662949D379" modified="2016-02-17" version="1">MRALRHLFAPSARWRFPPASLRRIAEAIAAGEAHHAGQLRFAVESRLGWRDLLAGRDARQAARAAFAQLGVWDTAGNNGVLLYLLLADHRIEIVADRGYARRIGDERWQAVCDGIQRALAAGEAEAAVLGGIAALNEIMAQAFPRSGAGAGNELADAPVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLB7</accession>
    <name>A0A0S2DLB7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59367">
        <property type="protein sequence ID" value="ALN59367"/>
        <property type="gene ID" value="GLE_4025"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4025"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3962"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="268" mass="28597" checksum="C0C2D03A893DF2BA" modified="2016-02-17" version="1">MHPAKSFERSALDLASTSVSHRSGSPATYPTLHIHSSPTVAGQGVFDLARDRTCRTTDYQGDRMKHICGLLLALCGAIPSPAASTPLLPINQLNVAEIENIERFLPATDTARDSNPLIDNKPLAPATSIGIFSFAESLQSNHGTEAANEFVSPTWGQAALIALWTVMSCLLLWLSQQVLADLGGLIVNRLISQNGRISLLLFASWLISAAAALSAVAGCLLLILVEFTTPSMSLFNLSGTLPAVVIIGVYVRAALLAILHPMSRVYRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLE6</accession>
    <name>A0A0S2DLE6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 14">Crossover junction endodeoxyribonuclease RuvC</fullName>
            <ecNumber evidence="11 14">3.1.21.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">Holliday junction nuclease RuvC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12 14">Holliday junction resolvase RuvC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14 15" type="primary">ruvC</name>
        <name evidence="15" type="ORF">GLE_4062</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 14">Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 14">
            <text>Endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction).</text>
            <dbReference type="EC" id="3.1.21.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="14">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 14">Belongs to the RuvC family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.10" evidence="11 14"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4062"/>
    <dbReference type="EnsemblBacteria" id="ALN59404">
        <property type="protein sequence ID" value="ALN59404"/>
        <property type="gene ID" value="GLE_4062"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4062"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4005"/>
    <dbReference type="OMA" id="AICHIWR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16962">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00034">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020563">
        <property type="entry name" value="X-over_junc_endoDNase_Mg_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002176">
        <property type="entry name" value="X-over_junc_endoDNase_RuvC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30194">
        <property type="entry name" value="PTHR30194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02075">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00696">
        <property type="entry name" value="RSOLVASERUVC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00228">
        <property type="entry name" value="ruvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01321">
        <property type="entry name" value="RUVC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 14" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="8 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 14 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 14" id="KW-0540">Nuclease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="14">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ALN59404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="174" mass="18580" checksum="597A74C60FE8B74A" modified="2016-02-17" version="1">MRILGIDPGSQRTGLGVIDVAADGRCTYVAARALKLLDAEDFPSRLGLLCEGLEAALDEFAPTQVAIETVFMDKSATSALKLGHARGAALATVVRRRIPISEYPPRVIKQSLVGRGAADKQQVQHMVRLLLNLPEVKLQADAADALAVALTHAHMSATAQRTGIATHQLRRRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLG3</accession>
    <name>A0A0S2DLG3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phospholipid-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3704</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3704"/>
    <dbReference type="EnsemblBacteria" id="ALN59048">
        <property type="protein sequence ID" value="ALN59048"/>
        <property type="gene ID" value="GLE_3704"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3704"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3648"/>
    <dbReference type="OMA" id="KSEGPMK"/>
    <dbReference type="OrthoDB" id="1948119at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007055">
        <property type="entry name" value="BON_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014004">
        <property type="entry name" value="Transpt-assoc_nodulatn_dom_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04972">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00749">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50914">
        <property type="entry name" value="BON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BON" evidence="2">
        <location>
            <begin position="340"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="483" mass="52513" checksum="BAA84E18A9175A46" modified="2016-02-17" version="1">MRKRKQARDDGRSDQVAGTAEFKAVAHEALRLGARALDKGRVWLNHIGSDDHGSEDMTQRQDSNGRDSESRRRPGGEDEQYRRRAPRGEEGESWMHDKERQAARTGYADYAYDPARGRGREYGHASADDHGRGGEYAREYGADAGESDARSGSRMPRDYDRGWREDGAPRERGQRAAYAREPGERGLYGAHGPGVRPAGPRGDAHYDSGWRARGFDERSQSVGWEDDRGDAPGGSSPRQGDPRHGYYVYGGERERRHDYDEFDPRRGRHDDYRPGRRRMGEGYGESSGYAGGEFAGSGYGAGFEPNREWSRERAFDAQSAYREQGMPTHRGRGPRNYARPDPRIEEELNERLTEDALVDASDIEVSCSQGKVVLNGEVDDRWMKHRAEDIADTCGGVKDVDNRLRVRGRENAPLAADPHRGGRGENAGRFGPTPAAKTPAGPASAAQGSGGAAGGNAGAGSSPGTGAGTSGAAPAGGGSMPQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLI7</accession>
    <name>A0A0S2DLI7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3955</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3955"/>
    <dbReference type="EnsemblBacteria" id="ALN59297">
        <property type="protein sequence ID" value="ALN59297"/>
        <property type="gene ID" value="GLE_3955"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3955"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3892"/>
    <dbReference type="OMA" id="NSPQNGP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012429">
        <property type="entry name" value="HGSNAT_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07786">
        <property type="entry name" value="HGSNAT_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="299"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="HGSNAT_cat" evidence="2">
        <location>
            <begin position="22"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="372" mass="40422" checksum="1AD45DA8FC9A7D67" modified="2016-02-17" version="1">MSAAPAQGPASAAAPRAPSPKRYASVDALRGLTVAAMLLVNDPGDWSHVYAPLLHSDWHGFTPTDLVFPMFLFIVGVSIALAMLPRLDAGTPKPALLRPALWRALRIFGLGLLLHLIAMWVVDREFLRVPGVLQRIGLCFAAAACIALYLPARAQWALWGALLLGYFGLLAAGGGYEPFVNIASRIDFAIFGAHVYQIDPASGRGHDPEGLVSTLGALATTLLGLRAGDWLRRGRMRALWVAGALGLGAGWALGLLQPINKNLWTPAYVLWAGGWSCWILALCHVLVDRRGWPPLGRAFGVNAIAAYAGSALLLYLLMALGWLEPLYRHGFADWMTPRFGPYLPSLAFALAFVALWWLVVRALDARRIYFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLJ6</accession>
    <name>A0A0S2DLJ6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dephospho-CoA kinase</fullName>
            <ecNumber evidence="2">2.7.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Dephosphocoenzyme A kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 3" type="primary">coaE</name>
        <name evidence="4" type="ORF">FE772_20195</name>
        <name evidence="3" type="ORF">GLE_4119</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>3'-dephospho-CoA + ATP = ADP + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18245"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57328"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 5/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the CoaE family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.24" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948800.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4119"/>
    <dbReference type="EnsemblBacteria" id="ALN59461">
        <property type="protein sequence ID" value="ALN59461"/>
        <property type="gene ID" value="GLE_4119"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4119"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4061"/>
    <dbReference type="OMA" id="QMDIEQK"/>
    <dbReference type="OrthoDB" id="1515383at2"/>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00356"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004140">
        <property type="term" value="F:dephospho-CoA kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00376">
        <property type="entry name" value="Dephospho_CoA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001977">
        <property type="entry name" value="Depp_CoAkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01121">
        <property type="entry name" value="CoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00152">
        <property type="entry name" value="TIGR00152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51219">
        <property type="entry name" value="DPCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="13"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="204" mass="21478" checksum="C91D72935DA0688D" modified="2016-02-17" version="1">MAAFCVGVTGGVASGKSEVTRRFEALGVTVADADLAARAAVAPGSDGLAEVAAAFGPQVLDADGGMDRAAMRRLVFNDDDARKRLEAIVHPRVRAMLQAQCAQAPGAYAIAAIPLLAEGGREAYPWLQRVLVVDVPVAVQQARVMRRDRIDAELAARMIAAQATREARLAIADDIVVNDGSLDALQAQVEALDRRYRAMAAAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLS3</accession>
    <name>A0A0S2DLS3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4265</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59606">
        <property type="protein sequence ID" value="ALN59606"/>
        <property type="gene ID" value="GLE_4265"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4265"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="45" mass="4808" checksum="8E21AF3A8EBB238D" modified="2016-02-17" version="1">MAVGQETFDRCAVGQQRAVGSAQCGQGSYRVGGHWGFGLFVFDRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLS5</accession>
    <name>A0A0S2DLS5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Bifunctional adenosylcobalamin biosynthesis protein</fullName>
            <ecNumber evidence="12">2.7.1.156</ecNumber>
            <ecNumber evidence="12">2.7.7.62</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">cobU</name>
        <name evidence="16" type="ORF">FE772_20040</name>
        <name evidence="15" type="ORF">GLE_4084</name>
    </gene>
    <organism evidence="15 17">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="15 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">C3</strain>
        </source>
    </reference>
    <reference evidence="16 18" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 12">Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>adenosylcob(III)inamide + ATP = adenosylcob(III)inamide phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15769"/>
            <dbReference type="ChEBI" id="CHEBI:2480"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58502"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.156"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>adenosylcob(III)inamide + GTP = adenosylcob(III)inamide phosphate + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15765"/>
            <dbReference type="ChEBI" id="CHEBI:2480"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58502"/>
            <dbReference type="EC" id="2.7.1.156"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 12">
            <text>adenosylcob(III)inamide phosphate + GTP + H(+) = adenosylcob(III)inamide-GDP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22712"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58502"/>
            <dbReference type="ChEBI" id="CHEBI:60487"/>
            <dbReference type="EC" id="2.7.7.62"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6 12">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 5/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 12">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 6/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 12">Belongs to the CobU/CobP family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.156" evidence="12"/>
    <dbReference type="EC" id="2.7.7.62" evidence="12"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948769.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4084"/>
    <dbReference type="EnsemblBacteria" id="ALN59426">
        <property type="protein sequence ID" value="ALN59426"/>
        <property type="gene ID" value="GLE_4084"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4084"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4026"/>
    <dbReference type="OMA" id="DCLTVWL"/>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00236"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043752">
        <property type="term" value="F:adenosylcobinamide kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008820">
        <property type="term" value="F:cobinamide phosphate guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00544">
        <property type="entry name" value="CobU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003203">
        <property type="entry name" value="Cobinamide_kinase/P_G-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34848">
        <property type="entry name" value="PTHR34848"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02283">
        <property type="entry name" value="CobU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006135">
        <property type="entry name" value="CobU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="12 14" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10 12 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 12 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12 15" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="GMP-histidine intermediate" evidence="13">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="7"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="31"/>
            <end position="33"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="48"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00003889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00007490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR006135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR006135-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR006135-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ALN59426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QCW27590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="172" mass="18204" checksum="0735BDC39D8ED8FF" modified="2016-02-17" version="1">MRTLILGGARSGKSALAERLAGAHADVVYLATAQPLDGEMDARIAHHRVRRPAAWGCVEEPIALADALRAHAAPQRCVLVDCLTLWLSNLLGANDPSLFHRERAALLDAVPALPGTVLFVSNEVGLGVVPMGELSRRFVDEAGRLHQALGEVCERVAFVAAGLPLVLKGPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLU5</accession>
    <name>A0A0S2DLU5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Electron transfer flavoprotein subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">etfA</name>
        <name evidence="7" type="ORF">GLE_4234</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ETF alpha-subunit/FixB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4234"/>
    <dbReference type="EnsemblBacteria" id="ALN59575">
        <property type="protein sequence ID" value="ALN59575"/>
        <property type="gene ID" value="GLE_4234"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4234"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4175"/>
    <dbReference type="OMA" id="WRPYAEQ"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01715">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001308">
        <property type="entry name" value="ETF_a/FixB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033947">
        <property type="entry name" value="ETF_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014731">
        <property type="entry name" value="ETF_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018206">
        <property type="entry name" value="ETF_asu_C_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153">
        <property type="entry name" value="PTHR43153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00766">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000089">
        <property type="entry name" value="Electra_flavoP_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00696">
        <property type="entry name" value="ETF_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ETF" evidence="6">
        <location>
            <begin position="1"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="309" mass="31088" checksum="DA9F7D754C8AA87B" modified="2016-02-17" version="1">MIVAEHLEGKLNASTAKCVSAAQALKPESIDIVVLAADPAGVAAQAAQIAGVNKVLAVANAANANAIAQVQAPQVAALAKGYSHVFGPSTTFGKDLMPCVAALLGVAQVSDVMAVEGSHTFKRPIYAGNAIVTVEAPADHAVVATVRTASWPEAAGGGSAAVEAASVDAALPSHTRYVGLAAGKSDRPDLQSAKRVVSGGRGVGSQENFKIIYDFADKLGAAVGASRAAVDAGYVPNELQVGQTGKIIAPELYVAVGISGAIQHLTGIKDAGTIVAINKDGEAPIFEIADIGLVGDLFKLLPELETALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLZ4</accession>
    <name>A0A0S2DLZ4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4166 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3999</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3999"/>
    <dbReference type="EnsemblBacteria" id="ALN59341">
        <property type="protein sequence ID" value="ALN59341"/>
        <property type="gene ID" value="GLE_3999"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3999"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3935"/>
    <dbReference type="OMA" id="WDRVFHF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025311">
        <property type="entry name" value="DUF4166"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13761">
        <property type="entry name" value="DUF4166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4166" evidence="1">
        <location>
            <begin position="10"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="191" mass="21913" checksum="3F03B8B3B7121F2D" modified="2016-02-17" version="1">MLGEDWHRLGEVIRRHYFLRAFSDDSICVKGVMREVWHSAIAKCLIPPARVFGALVPYRGTDVPIEVHYNVRPDDGTIHWDRVFHFAGRPPFHFLSYMEHVGGNDVIEFIRFGVGMRLKVTAEDGALVFRDKGYIWRMFGVDVPLPLGLLLGRAYIEERPVDAGRFSMRMTLTHPLFGELFRYGGDFSVGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM02</accession>
    <name>A0A0S2DM02_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Lactoylglutathione lyase</fullName>
            <ecNumber evidence="4 6">4.4.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Glyoxalase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">gloA</name>
        <name evidence="9" type="ORF">FE772_20105</name>
        <name evidence="8" type="ORF">GLE_4099</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>(R)-S-lactoylglutathione = glutathione + methylglyoxal</text>
            <dbReference type="Rhea" id="RHEA:19069"/>
            <dbReference type="ChEBI" id="CHEBI:17158"/>
            <dbReference type="ChEBI" id="CHEBI:57474"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="EC" id="4.4.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
        <text evidence="6">Binds 1 nickel ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the glyoxalase I family.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.5" evidence="4 6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948781.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4099"/>
    <dbReference type="EnsemblBacteria" id="ALN59441">
        <property type="protein sequence ID" value="ALN59441"/>
        <property type="gene ID" value="GLE_4099"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4099"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4041"/>
    <dbReference type="OMA" id="PRDGNMA"/>
    <dbReference type="OrthoDB" id="1984437at2"/>
    <dbReference type="UniPathway" id="UPA00619">
        <property type="reaction ID" value="UER00675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004462">
        <property type="term" value="F:lactoylglutathione lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004361">
        <property type="entry name" value="Glyoxalase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018146">
        <property type="entry name" value="Glyoxalase_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00068">
        <property type="entry name" value="glyox_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00934">
        <property type="entry name" value="GLYOXALASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00935">
        <property type="entry name" value="GLYOXALASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0533">Nickel</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="7">
        <location>
            <begin position="25"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW27598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="176" mass="19823" checksum="0D976BAE76173127" modified="2016-02-17" version="1">MSLQNELNAVPGVTAQPEAATRDFVFNHTMLRIKDPAASLDFYTRVLGFTLVRKRDFMDAKFSLYFLVLVNDPSQIPAEEPARGQWLLSQRGVLELTHNHGTENDADFAYHHGNSDPRGFGHICVSVPDVEAACARFEQLGVAFQKRLTDGRMKDIAFIKDPDGYWVEILQPTSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM29</accession>
    <name>A0A0S2DM29_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter, ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="12">ATP-binding cassette domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">FE772_20650</name>
        <name evidence="11" type="ORF">GLE_4213</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948875.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59554">
        <property type="protein sequence ID" value="ALN59554"/>
        <property type="gene ID" value="GLE_4213"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4213"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4155"/>
    <dbReference type="OMA" id="ESHIEIA"/>
    <dbReference type="OrthoDB" id="1489555at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="149"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="267"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="51"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="345"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="543"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="377"/>
            <end position="384"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN59554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW27687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="572" mass="63817" checksum="8ED451BA257F2C3D" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM64</accession>
    <name>A0A0S2DM64_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0502 protein FE772_20015</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_20015</name>
        <name evidence="2" type="ORF">GLE_4079</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0502 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4079"/>
    <dbReference type="EnsemblBacteria" id="ALN59421">
        <property type="protein sequence ID" value="ALN59421"/>
        <property type="gene ID" value="GLE_4079"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4079"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4021"/>
    <dbReference type="OMA" id="CNQKSSR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01584">
        <property type="entry name" value="UPF0502"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007432">
        <property type="entry name" value="DUF480"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38768">
        <property type="entry name" value="PTHR38768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04337">
        <property type="entry name" value="DUF480"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="225" mass="24074" checksum="3541ADA2BB535FF8" modified="2016-02-17" version="1">MSDIDPSAADDTPAAAVEAQLTPTEARVVAVLIEKEATTPDVYPLTLNAIVVACNQKTSRDPVTNLEQGEVAHALRQLEPRGWVKSHHSPRAERYSHRAGTALDATRPQTVLLALLMLRGPQTVNELLSRSDRMAKFDAAGDVQYALERLAQHQPPLVKLLGRQSGQREDRYGHLLCGEPQWTAAASGADPALASPAAQSALGERIAALEAKVAELEARLEAAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM68</accession>
    <name>A0A0S2DM68_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Energy-dependent translational throttle protein EttA</fullName>
            <ecNumber evidence="7">3.6.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Translational regulatory factor EttA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 12" type="primary">ettA</name>
        <name evidence="11" type="ORF">BV903_07750</name>
        <name evidence="13" type="ORF">D9T17_07935</name>
        <name evidence="12" type="ORF">FE772_20415</name>
        <name evidence="10" type="ORF">GLE_4163</name>
    </gene>
    <organism evidence="10 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 14">C3</strain>
        </source>
    </reference>
    <reference evidence="11 15" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 15">B25</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">OH11</strain>
        </source>
    </reference>
    <reference evidence="12 17" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="7">Associates with ribosomes and polysomes.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000015">
        <property type="protein sequence ID" value="OPD64546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000020">
        <property type="protein sequence ID" value="ROU07698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948839.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000020.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4163"/>
    <dbReference type="EnsemblBacteria" id="ALN59505">
        <property type="protein sequence ID" value="ALN59505"/>
        <property type="gene ID" value="GLE_4163"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64546">
        <property type="protein sequence ID" value="OPD64546"/>
        <property type="gene ID" value="BV903_07750"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4163"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4105"/>
    <dbReference type="OMA" id="ISYKPQY"/>
    <dbReference type="OrthoDB" id="1112046at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045900">
        <property type="term" value="P:negative regulation of translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00847">
        <property type="entry name" value="EttA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022374">
        <property type="entry name" value="EttA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43858">
        <property type="entry name" value="PTHR43858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03719">
        <property type="entry name" value="ABC_ABC_ChvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="2 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="5"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="323"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Arm" evidence="7">
        <location>
            <begin position="94"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="PtIM" evidence="7">
        <location>
            <begin position="241"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <begin position="355"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OPD64546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW27650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROU07698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="553" mass="61694" checksum="C24C68A1EE33C031" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM77</accession>
    <name>A0A0S2DM77_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4095</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59437">
        <property type="protein sequence ID" value="ALN59437"/>
        <property type="gene ID" value="GLE_4095"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4095"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4037"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046116">
        <property type="entry name" value="DUF6053"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19523">
        <property type="entry name" value="DUF6053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="60" mass="6432" checksum="F4448BE975B5D92E" modified="2016-02-17" version="1">MRYSRSARREDVPAVGTRVPTGGRRLCRKVLWEGSCGRSLWEVSVGGPSGPMLSGQVAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM98</accession>
    <name>A0A0S2DM98_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Thiol:disulfide interchange protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BV903_04190</name>
        <name evidence="11" type="ORF">FE772_20535</name>
        <name evidence="9" type="ORF">GLE_4187</name>
    </gene>
    <organism evidence="9 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">C3</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the thioredoxin family. DsbC subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000008">
        <property type="protein sequence ID" value="OPD65127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948855.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000008.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4187"/>
    <dbReference type="EnsemblBacteria" id="ALN59529">
        <property type="protein sequence ID" value="ALN59529"/>
        <property type="gene ID" value="GLE_4187"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65127">
        <property type="protein sequence ID" value="OPD65127"/>
        <property type="gene ID" value="BV903_04190"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4187"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4129"/>
    <dbReference type="OMA" id="QMIVYKA"/>
    <dbReference type="OrthoDB" id="1678187at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd03020">
        <property type="entry name" value="DsbA_DsbC_DsbG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033954">
        <property type="entry name" value="DiS-bond_Isoase_DsbC/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018950">
        <property type="entry name" value="DiS-bond_isomerase_DsbC/G_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009094">
        <property type="entry name" value="DiS-bond_isomerase_DsbC/G_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10411">
        <property type="entry name" value="DsbC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13098">
        <property type="entry name" value="Thioredoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54423">
        <property type="entry name" value="SSF54423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0574">Periplasm</keyword>
    <keyword evidence="5 6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5010000022" description="Thiol:disulfide interchange protein" evidence="6">
        <location>
            <begin position="21"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="DsbC_N" evidence="7">
        <location>
            <begin position="61"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin-like_fold" evidence="8">
        <location>
            <begin position="148"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN59529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD65127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW27666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="294" mass="30864" checksum="CC60A00E6C09CE74" modified="2016-02-17" version="1">MKRILFAVLGAISLSACAQAPQGAAAAAKTDPAKADAAQPAVPTGNAPKVAAGSADARAVEAVRTLNPKVDIDKVGPAPMPGFREAVVGGQVVYVSDDGRYLFLPGSGGALFDTKAKRNVMEDTLAGMRRDLLKTIPASERIVFAPPNPKHTVTIFTDVECGYCRKLHSEIAEYNRQGIAVEYLAFPRMGIGSEDYKKMVSVWCATDRRKALTDAKSDHGAVSSKQCKNSVEQQYEVGQRAGLTGTPMILNVDGVQLGGYVPPAQLREALDKLAAESKTAAKPAAAVATPVGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMH5</accession>
    <name>A0A0S2DMH5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Serine-type D-Ala-D-Ala carboxypeptidase</fullName>
            <ecNumber evidence="4">3.4.16.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">dacC</name>
        <name evidence="18" type="ORF">BV903_03370</name>
        <name evidence="17" type="ORF">GLE_4481</name>
    </gene>
    <organism evidence="17 19">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="17 19" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">C3</strain>
        </source>
    </reference>
    <reference evidence="18 20" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 20">B25</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the peptidase S11 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.4" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000006">
        <property type="protein sequence ID" value="OPD65342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949088.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4481"/>
    <dbReference type="EnsemblBacteria" id="ALN59822">
        <property type="protein sequence ID" value="ALN59822"/>
        <property type="gene ID" value="GLE_4481"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65342">
        <property type="protein sequence ID" value="OPD65342"/>
        <property type="gene ID" value="BV903_03370"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4481"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4418"/>
    <dbReference type="OMA" id="QNTHFQT"/>
    <dbReference type="OrthoDB" id="1499212at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015956">
        <property type="entry name" value="Peniciliin-bd_prot_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018044">
        <property type="entry name" value="Peptidase_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012907">
        <property type="entry name" value="Peptidase_S11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037167">
        <property type="entry name" value="Peptidase_S11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001967">
        <property type="entry name" value="Peptidase_S11_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07943">
        <property type="entry name" value="PBP5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00768">
        <property type="entry name" value="Peptidase_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00725">
        <property type="entry name" value="DADACBPTASE1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00936">
        <property type="entry name" value="PBP5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69189">
        <property type="entry name" value="SSF69189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 17" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="9" id="KW-0133">Cell shape</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 15" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594976" description="Serine-type D-Ala-D-Ala carboxypeptidase" evidence="15">
        <location>
            <begin position="27"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="PBP5_C" evidence="16">
        <location>
            <begin position="305"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="12">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR618044-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR618044-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ALN59822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="OPD65342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="413" mass="44066" checksum="A3050EB83FE1028B" modified="2016-02-17" version="1">MAPRAAAFAALTSAFLATAVAGLASAQAPAAKPAAAAATPAAAQPPASDSLPVPPPPQIAGTAWVLMDAASGNILASHEPDMRVEPASITKVMTSYVIAAEMAGGKVKDTDQVMMTENAWRKGGAATDGSYSGFEVNKTAPLVEMEKGMVVQSGNDAAIALAEHVAGSEDAFAALMNQYAARIGLKNSHFMNPHGLSQENHYSTAHDLALLGRALIHDFPTAYSYNKIKELKVGPITQPNRNLLLWRDSSVDGIKTGHHSKAGYCLMASAQRGDQRLISVVMGSSSEAQRASDSQALLNWGFRFFETHKLYDAGKAIAKQKVWKGQSAEVQLGVAEPLLVTVQRGKYPQLKPSMDVPKTLVAPIKKGQAIGMVKVMLDGKVVAQRPLVALAAVEEGGFFKRLWDEFWMWWESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMK4</accession>
    <name>A0A0S2DMK4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alginate biosynthesis regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">algR</name>
        <name evidence="4" type="ORF">GLE_4553</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4553"/>
    <dbReference type="EnsemblBacteria" id="ALN59894">
        <property type="protein sequence ID" value="ALN59894"/>
        <property type="gene ID" value="GLE_4553"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4553"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4489"/>
    <dbReference type="OMA" id="THISART"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="146"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="241" mass="26951" checksum="68046DF5226A929F" modified="2016-02-17" version="1">MIADDEPLARERLRGLLALRPDVEVVAEAADGQHALHACAEHRPDLVLLDIAMPGIDGLEAARHLAAFEPRPAVVFCTAYDAHALSAFEAEAIDYLVKPVRAERLDAALERVRTFAAGRERAGDGETAPGQVRSHLCARLRGSLRLIPIEDVHYLHAEEKYVIVHHARGEDLIEESLKSLEDEFGERFVRIHRNCLVARHEIVELKRNAEGHVQAILRHGKQPLEVSRRCVASLRETLKHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMV8</accession>
    <name>A0A0S2DMV8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_21475</name>
        <name evidence="2" type="ORF">GLE_4396</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949019.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59737">
        <property type="protein sequence ID" value="ALN59737"/>
        <property type="gene ID" value="GLE_4396"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4396"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4335"/>
    <dbReference type="OrthoDB" id="1976201at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="169" mass="18359" checksum="A7B038F5127D9DC0" modified="2016-02-17" version="1">MRTERLVVANARGKYLALLLCALAFVAIGALIVLRQPGLGGFLIGGASIAFFGAGAVLFAFQLLDRQPRLILDDDGLNDRTLGVGIIPWRDIADARLLSVRGHAFVCLQLRNPEHWADKLSPRQRRLAALNQRMGYAMLNVNLAGAAVDPQAVLQRILKSSAMYEPGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN86</accession>
    <name>A0A0S2DN86_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_22695</name>
        <name evidence="1" type="ORF">GLE_4655</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949215.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59996">
        <property type="protein sequence ID" value="ALN59996"/>
        <property type="gene ID" value="GLE_4655"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4655"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4591"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="95" mass="10314" checksum="FD46E81D1B1615D2" modified="2016-02-17" version="1">MDEKMSVDLIAQQLQSKGFVAEIYSVEPPVIHGGTETRQSRGIKVYARGFSVRRGDAVWLVSLPVGQTVEVSSVANAEDVAACVAAHFDQHGLWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN95</accession>
    <name>A0A0S2DN95_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">M23 peptidase/bacterial SH3 domain protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Metalloendopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_15930</name>
        <name evidence="3" type="ORF">GLE_4705</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000041">
        <property type="protein sequence ID" value="OPD62958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949249.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4705"/>
    <dbReference type="EnsemblBacteria" id="ALN60046">
        <property type="protein sequence ID" value="ALN60046"/>
        <property type="gene ID" value="GLE_4705"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62958">
        <property type="protein sequence ID" value="OPD62958"/>
        <property type="gene ID" value="BV903_15930"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4705"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4639"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003646">
        <property type="entry name" value="SH3-like_bac-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08239">
        <property type="entry name" value="SH3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00287">
        <property type="entry name" value="SH3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51781">
        <property type="entry name" value="SH3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595497" evidence="1">
        <location>
            <begin position="30"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="SH3b" evidence="2">
        <location>
            <begin position="179"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD62958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="258" mass="26606" checksum="C2461B4E5341BC93" modified="2016-02-17" version="1">MNVRANRFRTRSALALLAFASLFGTAAQAAPTFQMPFPCGQVWEGQTRTNHNPQNSVDFNRANDEGDTVVAAAAGTVSVVRNLGSTSYGKYVVIDHGGGWSTLYAHLNSYSVSVGQNVAIGKSIGTVGSTGGSTGPHLHFEQRLNGAAQKIKFNGAQIAYWGSASYTSRNSCGGGGGAAGTVNTSGTPLNVRSGPGTSYSIVGSLADGAQVTIQCQTTGTSVSGTYGTSNIWNRIGSGRFIPDAYTYTGSDGRVAPNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN99</accession>
    <name>A0A0S2DN99_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4709</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60050">
        <property type="protein sequence ID" value="ALN60050"/>
        <property type="gene ID" value="GLE_4709"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4709"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4643"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="108" mass="11517" checksum="32ED2AB759E0EED5" modified="2016-02-17" version="1">MAGRVAAVRAPRGSARRRTATPLRVRCRGRDGLATRRPGPRPLARGRADPVVRTRAPAPTSAVVPAVVTVVMSVPVLGLPPVPNLNTRSYRGGLGASRRPQAKTRDQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNK3</accession>
    <name>A0A0S2DNK3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLE_4890</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4890"/>
    <dbReference type="EnsemblBacteria" id="ALN60231">
        <property type="protein sequence ID" value="ALN60231"/>
        <property type="gene ID" value="GLE_4890"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4890"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4821"/>
    <dbReference type="OMA" id="MHKELSR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="9">
        <location>
            <begin position="156"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="212"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="430"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN60231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="455" mass="50919" checksum="CAD861CDEBCE02A2" modified="2016-02-17" version="1">MLVRLYLTVAGLLLCSILLVQQVFPYLFPDQYSASVRHEFVGELTLLRERLGDAAGAELDRRLAELNRRTPERYSRVTAQELRALPARNRAELARLGSASTHVGSERHHLFLRLPAGDTVQIVYTENDFPIRYVAYLTVFAMVLLGLMIWLQPHWRDLERLRDAAAQFGDGDLGARARVRGGSSIRQLCVFFNNMADQIGRLIQSQRDMVNAASHELRTPITRLEFGLANLADTLDDRVARARVHALRCDVEELDLLVGELLTLGMLERSGPRPSLEPVQLEGFLRASTGVSADELRSRATRIEWAISAELDEVAVEPRSLRRAFSNLMRNAVRYADSAIRVAAEPAGNDWLLIVEDDGVGIPAEDRRRVFEPFYRLDRSRDRATGGYGLGLSIVRQVIERHGGTVHVEPSPLGGARFVARLPQRPRLWSERDGAAVGEAEAGPGDAQERPFHLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNR7</accession>
    <name>A0A0S2DNR7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide repeat domain protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_10570</name>
        <name evidence="4" type="ORF">FE772_23535</name>
        <name evidence="2" type="ORF">GLE_4847</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000023">
        <property type="protein sequence ID" value="OPD64022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949356.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4847"/>
    <dbReference type="EnsemblBacteria" id="ALN60188">
        <property type="protein sequence ID" value="ALN60188"/>
        <property type="gene ID" value="GLE_4847"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64022">
        <property type="protein sequence ID" value="OPD64022"/>
        <property type="gene ID" value="BV903_10570"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4847"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4777"/>
    <dbReference type="OMA" id="DHNREWL"/>
    <dbReference type="OrthoDB" id="1525278at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014562">
        <property type="entry name" value="UCP030959_TPR_rpt-cont"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF030959">
        <property type="entry name" value="UCP030959"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="251" mass="27986" checksum="CC92A8244756DEEA" modified="2016-02-17" version="1">MPYFGLGLHVLVALCFAVHAVRSGQDRYWLMILFMFPLLGSVVYAFAIWLPEQRHSRHGRALVGNVRRMLDPGRELREAQDAFDTSATTDNRLRLADALLGAGRAGDALPLYRAALGGVHRDDPHIQVKLAHALLEAGEPAQARQLLDELIAKRPDFRSPEGHLAYARAVAAQGDRAKAKEEFEALVGYSSGFEAHARYAECLIGWGELGRARELCEQVQAKARRLPAYARKMHKPDLDKLKELDKRAQAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNV5</accession>
    <name>A0A0S2DNV5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF1801 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_21930</name>
        <name evidence="3" type="ORF">GLE_4491</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057950290.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4491"/>
    <dbReference type="EnsemblBacteria" id="ALN59832">
        <property type="protein sequence ID" value="ALN59832"/>
        <property type="gene ID" value="GLE_4491"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4491"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4428"/>
    <dbReference type="OMA" id="RYFHIHE"/>
    <dbReference type="OrthoDB" id="1278667at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014922">
        <property type="entry name" value="DUF1801"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08818">
        <property type="entry name" value="DUF1801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1801" evidence="2">
        <location>
            <begin position="86"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="187" mass="20168" checksum="A1AB41623B4FCB7C" modified="2016-02-17" version="1">MTAKTSKSAAKAAAKPAAKPATKTAKAKAGKPADVTPASRRKAATAKPGKPAASGPRLLSGGNPQIPKGHGDAPVQAYLDAVPGWKREIARRLDALVERTVPGVSKAVKWNTPLYAVEEGHWFLAMHCFDRYLKVTFFRGAALDPPPAHASKMADVRYHHIHEHDPFDEARLADWIAQASRLPGERM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNX8</accession>
    <name>A0A0S2DNX8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF364 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_24325</name>
        <name evidence="2" type="ORF">GLE_5018</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949489.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5018"/>
    <dbReference type="EnsemblBacteria" id="ALN60359">
        <property type="protein sequence ID" value="ALN60359"/>
        <property type="gene ID" value="GLE_5018"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5018"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4946"/>
    <dbReference type="OrthoDB" id="1462062at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007161">
        <property type="entry name" value="DUF364"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04016">
        <property type="entry name" value="DUF364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF364" evidence="1">
        <location>
            <begin position="141"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="279" mass="29822" checksum="A265E9AFD04B291E" modified="2016-02-17" version="1">MRTPAPTTVADLTEAVLRGAHGPDPAALHAVGAFWVRQSTQFPGTDTKYRNYYLVLRAESAFGGCCLERDQLDSAIAEELSGRSLAELLRDPRTPVRIAALDAYLALAYPHREQAQARAQLLPHGTPLERAKARDAAIAGLLDIRPGMRVGLIGVVNPLVEAIRARGGVCLPCDFNLKHTADGTEVVADMELVLAQADMVIATGMTLSNGSFDRIVEVARERGTGLVVYAQTGSAIVPRFLGHGVSAVSAEPFPFSQFSADPTPIHLYRADGLDAREAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP43</accession>
    <name>A0A0S2DP43_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Exodeoxyribonuclease III</fullName>
            <ecNumber evidence="4">3.1.11.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">xth</name>
        <name evidence="5" type="ORF">FE772_24290</name>
        <name evidence="4" type="ORF">GLE_5009</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.2" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949484.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5009"/>
    <dbReference type="EnsemblBacteria" id="ALN60350">
        <property type="protein sequence ID" value="ALN60350"/>
        <property type="gene ID" value="GLE_5009"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5009"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4937"/>
    <dbReference type="OMA" id="WWSYRGR"/>
    <dbReference type="OrthoDB" id="1893707at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008853">
        <property type="term" value="F:exodeoxyribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09086">
        <property type="entry name" value="ExoIII-like_AP-endo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004808">
        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020847">
        <property type="entry name" value="AP_endonuclease_F1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020848">
        <property type="entry name" value="AP_endonuclease_F1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037493">
        <property type="entry name" value="ExoIII-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43250">
        <property type="entry name" value="PTHR43250"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00633">
        <property type="entry name" value="xth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00726">
        <property type="entry name" value="AP_NUCLEASE_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00728">
        <property type="entry name" value="AP_NUCLEASE_F1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51435">
        <property type="entry name" value="AP_NUCLEASE_F1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="3">
        <location>
            <begin position="4"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW28302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="255" mass="28796" checksum="21FCD4808E42638C" modified="2016-02-17" version="1">MKIVSWNVNSLNVRLPHLQQWLAAFAPDVVALQETKLEDSRFPDTALAEAGYRSVFAGQKTYNGVAILSREAAQDVQIGIPGFEDEQKRVIAATVGGLRIIDLYVVNGQDVGTDKYAYKLRWLDAVHAWVQDELSRHPDLIVLGDFNIAPEARDTHDPAVWNDSHILTSTAERDALQRLLSLGLHDAFRLFPQEENAFSWWDYRQAGFRRNLGLRIDLTLVSESLRARCVAAGIDREPRTWDRPSDHAPAWVELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP67</accession>
    <name>A0A0S2DP67_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phospholipase accessory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_5166</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949602.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5166"/>
    <dbReference type="EnsemblBacteria" id="ALN60507">
        <property type="protein sequence ID" value="ALN60507"/>
        <property type="gene ID" value="GLE_5166"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5166"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5088"/>
    <dbReference type="OMA" id="QNEWGLT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595555" evidence="2">
        <location>
            <begin position="41"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="122"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="189"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="265" mass="27119" checksum="0FC91582D7E9E86B" modified="2016-02-17" version="1">MASLIHGSRHAPVARSRALAAARAAAAALGLWLCLSAASAQPGVRAMQAREVFPAATAAELAEAAAGGDAARVRALVAAGADPDARGARGITVLQWALYQRSVAGLRALLDAGADPARGADDGATVLQLAAMADDPQYLRALLDAKVDPNLTNTVTGAGALASALMAERAGNFAALLAAGADPGRADCMGNTPLHVAAKINEFGHALTLLRAGADPGARNAQGVTFQRYMFMSPDRLLNARTRSEREAAIAWLRERGVAVENAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP81</accession>
    <name>A0A0S2DP81_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein-export protein SecB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 4" type="primary">secB</name>
        <name evidence="5" type="ORF">BV903_18295</name>
        <name evidence="7" type="ORF">D9T17_04435</name>
        <name evidence="6" type="ORF">FE772_24390</name>
        <name evidence="4" type="ORF">GLE_5031</name>
    </gene>
    <organism evidence="4 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 8">C3</strain>
        </source>
    </reference>
    <reference evidence="5 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">OH11</strain>
        </source>
    </reference>
    <reference evidence="6 11" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the SecB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000049">
        <property type="protein sequence ID" value="OPD62486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000013">
        <property type="protein sequence ID" value="ROU08325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949501.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5031"/>
    <dbReference type="EnsemblBacteria" id="ALN60372">
        <property type="protein sequence ID" value="ALN60372"/>
        <property type="gene ID" value="GLE_5031"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62486">
        <property type="protein sequence ID" value="OPD62486"/>
        <property type="gene ID" value="BV903_18295"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5031"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4959"/>
    <dbReference type="OMA" id="CPNVLFP"/>
    <dbReference type="OrthoDB" id="1624074at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051262">
        <property type="term" value="P:protein tetramerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00821">
        <property type="entry name" value="SecB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003708">
        <property type="entry name" value="SecB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035958">
        <property type="entry name" value="SecB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36918">
        <property type="entry name" value="PTHR36918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02556">
        <property type="entry name" value="SecB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01594">
        <property type="entry name" value="SECBCHAPRONE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54611">
        <property type="entry name" value="SSF54611"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00809">
        <property type="entry name" value="secB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD62486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW28320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROU08325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="169" mass="17939" checksum="34FD1769D74229AC" modified="2016-02-17" version="1">MSEENVNGAAAPAEAATGPAFTVEKIYVKDVSFEVPGAPAVFAETQQPQLQLNLSQNVQRVGDNAFEVVLGVTLTCTAGDKPMYLAEVKQAGVFGLIGFDEQTLDAMLGTHCPNVLYPYARQLVSDLIQAGGFPPFFLQPINFDALYAEGLRQRASQGNLADAETAGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPC1</accession>
    <name>A0A0S2DPC1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5178</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60519">
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        <property type="gene ID" value="GLE_5178"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="46" mass="5000" checksum="70B03FAB4B08C629" modified="2016-02-17" version="1">MTRLHSTPSPRKSDLPDPIVAAAGFSTHKMKSFSFSCSAKMCLNSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPW0</accession>
    <name>A0A0S2DPW0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_22350</name>
        <name evidence="4" type="ORF">FE772_23675</name>
        <name evidence="2" type="ORF">GLE_4875</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
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            <taxon>Lysobacter</taxon>
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    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD61714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW28197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949380.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000074.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60216">
        <property type="protein sequence ID" value="ALN60216"/>
        <property type="gene ID" value="GLE_4875"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61714">
        <property type="protein sequence ID" value="OPD61714"/>
        <property type="gene ID" value="BV903_22350"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4875"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4806"/>
    <dbReference type="OrthoDB" id="1962607at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595546" evidence="1">
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            <begin position="27"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="142" mass="14707" checksum="54AF3D0DC54C06AE" modified="2016-02-17" version="1">MRINTSIGLGAVALALAMGHVAPAQAGNVTGAGMVCYVDTFRYDIPTPDTCSSWWVPNGAHHTSVAVFSVTGLPAGNYGFVWRDLETNAIVASCANQNACAVPITTDLAGDGVAIVQATVTDLDTGASQQVQATAYYYDGYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPW2</accession>
    <name>A0A0S2DPW2_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="2 4">
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        <lineage>
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    <reference evidence="2 4" key="1">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60445">
        <property type="protein sequence ID" value="ALN60445"/>
        <property type="gene ID" value="GLE_5104"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5104"/>
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    <dbReference type="OrthoDB" id="1887421at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031869">
        <property type="entry name" value="YscO-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16789">
        <property type="entry name" value="YscO-like"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="82"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="168" mass="19156" checksum="E50437DF0CFA70CE" modified="2016-02-17" version="1">MNKQRFPLATLLQLREHRVETARALVMERQAQVQARREACTAIEGEIVALNQERASQRLRLLDPPPAGVPWAMAMAQREAHVDHLAELANAARQRLADAQGKLREAEAALDEARKAFFRAKSRLEALEKRRDVWRKEQSAIAQRREEAQSADLLLAARQRSTHHNSPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQB8</accession>
    <name>A0A0S2DQB8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rluE</name>
        <name evidence="6" type="ORF">BV903_05090</name>
        <name evidence="7" type="ORF">FE772_00155</name>
        <name evidence="5" type="ORF">GLE_5373</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000009">
        <property type="protein sequence ID" value="OPD65111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949758.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5373"/>
    <dbReference type="EnsemblBacteria" id="ALN60714">
        <property type="protein sequence ID" value="ALN60714"/>
        <property type="gene ID" value="GLE_5373"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65111">
        <property type="protein sequence ID" value="OPD65111"/>
        <property type="gene ID" value="BV903_05090"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5373"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5288"/>
    <dbReference type="OMA" id="HPRTYWV"/>
    <dbReference type="OrthoDB" id="1037615at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00093">
        <property type="entry name" value="TIGR00093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="4">
        <location>
            <begin position="2"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD65111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW24311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="178" mass="19553" checksum="3074B609CA5538EA" modified="2016-02-17" version="1">MLIALNKPYGALSQFTDRSQPPKPTLAGFGLPAGVYAAGRLDHDSEGLLLLTDDGTLAHRLTDPRHKQAKTYLVQVEGAPDEAQLRRLRDGVELNDGPTLPAQARAVAAPDWLWPRDPPVRFRKTVPDAWLELSIGEGRNRQVRRMTAAVGLPTLRLIRVAIGPHRLDGLAPGQWRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQC0</accession>
    <name>A0A0S2DQC0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_05545</name>
        <name evidence="1" type="ORF">GLE_5481</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000010">
        <property type="protein sequence ID" value="OPD64955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60822">
        <property type="protein sequence ID" value="ALN60822"/>
        <property type="gene ID" value="GLE_5481"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64955">
        <property type="protein sequence ID" value="OPD64955"/>
        <property type="gene ID" value="BV903_05545"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5481"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5395"/>
    <dbReference type="OrthoDB" id="2126226at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD64955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="114" mass="12343" checksum="8BEBFEE936EA4FB2" modified="2016-02-17" version="1">MSNAVVTCYVDTFAVDVPEAFTCFSTWKPGKATNPTNAYFQVVGLGQGNYSYAWLDVETNTVPANCGNQSLCRKSIATETRNDGEATLRVTITDLDTGESKSAQATAFYNDGYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQT5</accession>
    <name>A0A0S2DQT5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5492</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60833">
        <property type="protein sequence ID" value="ALN60833"/>
        <property type="gene ID" value="GLE_5492"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5492"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5407"/>
    <dbReference type="OMA" id="RNDSEWI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021417">
        <property type="entry name" value="DUF3060"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11259">
        <property type="entry name" value="DUF3060"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="114" mass="12192" checksum="4C40FB81918E9822" modified="2016-02-17" version="1">MRITKSDFETVLNGQCGAVVITGSNGSVNVDHAQSIRVEGTKVTVLNEKVETLEAIGSDNTFNMTEVGHATIAGNRNTLLGRNYRQVTFKGQGNAVNTDNEPQLDDQGTGNKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DRN3</accession>
    <name>A0A0S2DRN3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA (cytosine-5-)-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FE772_00765</name>
        <name evidence="9" type="ORF">GLE_5515</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5515"/>
    <dbReference type="REBASE" id="132001">
        <property type="entry name" value="M.LenC3ORF5515P"/>
    </dbReference>
    <dbReference type="REBASE" id="342050">
        <property type="entry name" value="M.LenYC36ORF765P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60856">
        <property type="protein sequence ID" value="ALN60856"/>
        <property type="gene ID" value="GLE_5515"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5515"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5428"/>
    <dbReference type="OMA" id="FTQCHFF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031303">
        <property type="entry name" value="C5_meth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00095">
        <property type="entry name" value="C5_MTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0680">Restriction system</keyword>
    <keyword evidence="5 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 7 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="173"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN60856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW24415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="303" mass="33304" checksum="930B118E8218A6FE" modified="2016-02-17" version="1">MPAYYNEVDPYLCQWLRNLMKARLIPPGDTDDRDIRSVPADDIRGYNQCHFFAGIGGFAYAARLAGWPDSAPLWTGGFPCQPFSVAGNQRAQADDRHLWPELHRLIAQARPALFLGENVAGLIPLGLDGVLSDLEGEGYASRAVVVPACAVDAPHRRDRVWIVGRRLADRNGQRSGEARRLCGRATQWPAGRSEGGVEHTARERWGEGRAEPELRQRRDPPAAGASGMGNTDDAGSQRRVERWQRAGQWDAWATGRTLAGRRIPESGIRLLAHGIPARIPRLRAAGNAIVPQVAAEILRALRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-06-16" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>C3PTT3</accession>
    <name>C3PTT3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HSAF FAD dependent oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">NAD(P)/FAD-dependent oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Ox3</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Phytoene dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BV903_09195</name>
        <name evidence="7" type="ORF">FE772_15985</name>
        <name evidence="5" type="ORF">GLE_3218</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2007" name="Antimicrob. Agents Chemother." volume="51" first="64" last="72">
            <title>Structure and biosynthesis of heat-stable antifungal factor (HSAF), a broad-spectrum antimycotic with a novel mode of action.</title>
            <authorList>
                <person name="Yu F."/>
                <person name="Zaleta-Rivera K."/>
                <person name="Zhu X."/>
                <person name="Huffman J."/>
                <person name="Millet J.C."/>
                <person name="Harris S.D."/>
                <person name="Yuen G."/>
                <person name="Li X.C."/>
                <person name="Du L."/>
            </authorList>
            <dbReference type="PubMed" id="17074795"/>
            <dbReference type="DOI" id="10.1128/AAC.00931-06"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">C3</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2009-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Du L."/>
                <person name="Xie Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">C3</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="4">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="5">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="EF028635">
        <property type="protein sequence ID" value="ACP19698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000020">
        <property type="protein sequence ID" value="OPD64215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN58564">
        <property type="protein sequence ID" value="ALN58564"/>
        <property type="gene ID" value="GLE_3218"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64215">
        <property type="protein sequence ID" value="OPD64215"/>
        <property type="gene ID" value="BV903_09195"/>
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    <dbReference type="KEGG" id="lez:GLE_3218"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3172"/>
    <dbReference type="OMA" id="NTCMISI"/>
    <dbReference type="OrthoDB" id="418913at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016116">
        <property type="term" value="P:carotenoid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="2"/>
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        <property type="entry name" value="FAD/NAD-bd_sf"/>
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        <location>
            <begin position="552"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ACP19698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD64215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW26912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="575" mass="64915" checksum="F6C2C9C8932F2ED4" modified="2009-06-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAJ3</accession>
    <name>A0A0S2DAJ3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">5'-nucleotidase, lipoprotein e(P4) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0098</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945794.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0098"/>
    <dbReference type="EnsemblBacteria" id="ALN55457">
        <property type="protein sequence ID" value="ALN55457"/>
        <property type="gene ID" value="GLE_0098"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0098"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.102"/>
    <dbReference type="OMA" id="DSEWEPR"/>
    <dbReference type="OrthoDB" id="1535353at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="HAD_CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Acid_phosphat_B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
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        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006423">
        <property type="entry name" value="Lipo_e_P4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03767">
        <property type="entry name" value="Acid_phosphat_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019271">
        <property type="entry name" value="Acid_Ptase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01125">
        <property type="entry name" value="C1.1:_Acid_Phosphatase_Like"/>
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    </dbReference>
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        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595154" evidence="2">
        <location>
            <begin position="23"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="315" mass="34088" checksum="82096ED2DBFF7AAE" modified="2016-02-17" version="1">MQIRASLVRVPVAALACALALAACKPQPGQPADAAAPAAPAAKPDAAAAAPAAAAKPTGADDNLNAVLWMQRSVEYRASAETIYRAAADKLDVALKQPNWDALVPDERGNAAKGLKPAVVMDVDETVLDNSPYQARLVRDGKEYDEVTWDAWVAEKKAKPVPGVVEFAKAAQAKGVTILYLSNRAVHLKEATLANLRSVGLPVADDSVFLGLGTVVDGCEQNGSEKNCRRLLAGKQYRVLMQFGDQIGDFVQVVANTPEGRDGLLEQYHDWFGERWWMLPNPSYGSWEAMTFNNDYSQSRDTRREAKRKALDVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAQ4</accession>
    <name>A0A0S2DAQ4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Probable chromosome-partitioning protein ParB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">BV903_22685</name>
        <name evidence="9" type="ORF">D9T17_01915</name>
        <name evidence="8" type="ORF">FE772_01755</name>
        <name evidence="6" type="ORF">GLE_0176</name>
    </gene>
    <organism evidence="6 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 10">C3</strain>
        </source>
    </reference>
    <reference evidence="7 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">OH11</strain>
        </source>
    </reference>
    <reference evidence="8 13" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ParB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000076">
        <property type="protein sequence ID" value="OPD61638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000006">
        <property type="protein sequence ID" value="ROU08868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945851.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0176"/>
    <dbReference type="EnsemblBacteria" id="ALN55535">
        <property type="protein sequence ID" value="ALN55535"/>
        <property type="gene ID" value="GLE_0176"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61638">
        <property type="protein sequence ID" value="OPD61638"/>
        <property type="gene ID" value="BV903_22685"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0176"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.178"/>
    <dbReference type="OMA" id="IALSYQR"/>
    <dbReference type="OrthoDB" id="653368at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041468">
        <property type="entry name" value="HTH_ParB/Spo0J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004437">
        <property type="entry name" value="ParB/RepB/Spo0J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB/Sulfiredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17762">
        <property type="entry name" value="HTH_ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02195">
        <property type="entry name" value="ParBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00470">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00180">
        <property type="entry name" value="parB_part"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ParB" evidence="5">
        <location>
            <begin position="39"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN55535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD61638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW24591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROU08868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="305" mass="33222" checksum="3AA7A1EA3D3073B3" modified="2016-02-17" version="1">MSNPAKKRGLGRGLEALLGPKAAAEAPTLVEAQPGDLLRHLPVDSLSAGKYQPRKHWDEEKLAELAESIKAQGVIQPIVVREIGERGGKTYEIIAGERRWRASRLAGLAEIPVVIREVDDRTVVAMALIENIQREDLNPLEEAQALTRLIDEFDLTHAQAAEAVGRSRAAVSNLLRLLELPGEIRVLVETRSLEMGHARALLTLAPQAAIALARQAAELGWSVRDVEHRVQQLAAGKIPVAGKPKPAKLKPQADIVTLERELSESLNTKVNVLHGRGGKGRLVIHYTDLDSLDGVLEKLRGKVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAS8</accession>
    <name>A0A0S2DAS8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Outer membrane protein, FadL family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FE772_02225</name>
        <name evidence="8" type="ORF">GLE_0279</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the OmpP1/FadL family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0279"/>
    <dbReference type="EnsemblBacteria" id="ALN55637">
        <property type="protein sequence ID" value="ALN55637"/>
        <property type="gene ID" value="GLE_0279"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0279"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.278"/>
    <dbReference type="OMA" id="KQENWED"/>
    <dbReference type="OrthoDB" id="620166at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005017">
        <property type="entry name" value="OMPP1/FadL/TodX"/>
    </dbReference>
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        <property type="entry name" value="PTHR35093"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Toluene_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
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    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN55637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW24661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="453" mass="48367" checksum="241B735E39DF96CF" modified="2016-02-17" version="1">MQPSHRTIRLTAIALGVAGVISFGSAGATGFQIRENSVKNQGRAFAGSAVSEKDASVVSNNPAAMVNLDSTTIRGDVTAIDLTAKFTGNGTAAAGTPLARPMTGGNGGDPGDVTPVPALSIVVPLSGSFEKLTLGAQLSAPFGLKTEYDPNWIGRYSAIESEVKTIDLTLSAAVKLTDRFSVGAGFVYERAEATLTNAVDFGGLICRMRPAACAVPNTPYGPQRADGLAKVKGDDTGIGWILGFQWKPTDRLAIGYSHRSEIDHDLEGTVTFTKPASVAPLLANTVYNTAPGGAALTTPSTDTLSVSYAFSDQFRMMFDAQKTDWHSLQTVEIKRFDGIDISKEEFQWEDTMMYALGAEYDLNDRFTLRGGIAKDETPTNDTHRTPRLPDNDRTLYSVGLTWNANEHLSVDAAFTRIQIDSPDVDIVSTSGSTLVGKFKGHANLFGVSAQYKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBD1</accession>
    <name>A0A0S2DBD1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0475</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55833">
        <property type="protein sequence ID" value="ALN55833"/>
        <property type="gene ID" value="GLE_0475"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0475"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.471"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="41" mass="4102" checksum="FB26A27317F159FD" modified="2016-02-17" version="1">MRQPVPGLEVREVRVPFAGVRARPAAGGAVAATMAAATVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBF9</accession>
    <name>A0A0S2DBF9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0509</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55867">
        <property type="protein sequence ID" value="ALN55867"/>
        <property type="gene ID" value="GLE_0509"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0509"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.504"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="83" mass="8805" checksum="A633E9FE99CA8610" modified="2016-02-17" version="1">MARSPGIHHTRRPGAXXXXXXXTPPRRRPACTAGRRTPAPPSSRCARRRGPSAGVCNGNHDALASLALVRQRRGSSLSPAPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBL2</accession>
    <name>A0A0S2DBL2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_03520</name>
        <name evidence="1" type="ORF">GLE_0560</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW24878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946125.1">
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55918">
        <property type="protein sequence ID" value="ALN55918"/>
        <property type="gene ID" value="GLE_0560"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0560"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.554"/>
    <dbReference type="OMA" id="KFYRQAT"/>
    <dbReference type="OrthoDB" id="1684578at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="137" mass="14670" checksum="861FBCECE1772641" modified="2016-02-17" version="1">MAVYAIKTEVGDSAARAFAFAAQKTMYGGKRIAAGDTVYLFASENAGGAGLFARGTVVAAEAVAPRPGVARQTPRVSVRIRRTATARRPLGRAELKPHAQWDDGRPQTELNFKFYRQATDKIVGLSDAAAAFLDAHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-06-17" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBN8</accession>
    <name>A0A0S2DBN8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0583</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55941">
        <property type="protein sequence ID" value="ALN55941"/>
        <property type="gene ID" value="GLE_0583"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0583"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.576"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="94" mass="10222" checksum="982609CE7C939A6D" modified="2016-02-17" version="1">MSPAFADRVLRDSHSRIDAHRQARCRRRASIHGRNATIDDATGVGSNPNKRRDCGSLAALLASRARPPRVRRLPPAAIRAAQHGTHAGFGVRPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBS8</accession>
    <name>A0A0S2DBS8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Endoribonuclease L-PSP family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">RidA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_03215</name>
        <name evidence="1" type="ORF">GLE_0495</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946079.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0495"/>
    <dbReference type="EnsemblBacteria" id="ALN55853">
        <property type="protein sequence ID" value="ALN55853"/>
        <property type="gene ID" value="GLE_0495"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0495"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.490"/>
    <dbReference type="OMA" id="RHALYEE"/>
    <dbReference type="OrthoDB" id="1850770at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd02198">
        <property type="entry name" value="YjgH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038743">
        <property type="entry name" value="YjgH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="133" mass="14769" checksum="1CF185B4F50D6D66" modified="2016-02-17" version="1">MSRRDAVFPATRHDLYRQHRYSPAIRSGGFLFVSGQVGSREDGSPEPDFVAQVRLAFDNLAAVLAAAGCTFDDIVDVTTFHTDPQRQFDTIQQVRLQVMGEPPYPNWTAIGVNWLAGFDFEIKIIARLPEGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBW9</accession>
    <name>A0A0S2DBW9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Integral membrane protein DUF6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0669</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56027">
        <property type="protein sequence ID" value="ALN56027"/>
        <property type="gene ID" value="GLE_0669"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0669"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.658"/>
    <dbReference type="OMA" id="AIPGWVP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="265"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="11"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="154"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="294" mass="31373" checksum="9DC25D3FC59C6D30" modified="2016-02-17" version="1">MTAANPHARRAIATMLAAVLMFSMMDALLKLLSEHYPPFQVATLRGASSLPFVLAWAFASGGGRSLLRVRWPLHLLRGALGIGMMASFVYGVNRLPLSTAYSIFFIAPLLITALSGPVLGERVGPRRWVAIGIGLLGVLVLLRPTGAGMFSVAALAILGAALGYAVTAITVRVLARTDSTQAMMVWLMTLMTLGAGALAWQDWVPLRAEHAWLIAGLGVAGSLGQYAVTEAFRLGEASLIAPLEYTALIWGVILDLTLWGVLPDAVTWIGAAIIVASGLYLLRRERVHLEAEHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC35</accession>
    <name>A0A0S2DC35_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TfoX C-domain superfamily</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">TfoX/Sxy family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_04270</name>
        <name evidence="3" type="ORF">GLE_0716</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW25004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946244.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0716"/>
    <dbReference type="EnsemblBacteria" id="ALN56074">
        <property type="protein sequence ID" value="ALN56074"/>
        <property type="gene ID" value="GLE_0716"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0716"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.704"/>
    <dbReference type="OrthoDB" id="2053274at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007077">
        <property type="entry name" value="TfoX_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04994">
        <property type="entry name" value="TfoX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TfoX_C" evidence="2">
        <location>
            <begin position="5"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="154" mass="16481" checksum="C5C7285CB74D6667" modified="2016-02-17" version="1">MSGTKMRNIGPKSAAWLRQVGLRTHEDVAAIGTVEAFMRVKRAGFKPTLNLLYAIEGALLDCHWQEIPDERRQELILAAEAATALLPAPRNKPAAAPVRTTVHNEDRHEDSGFGGFGAGREEGGHGGDGDGAGDERDDDGATGDNGRDEDGRHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCD1</accession>
    <name>A0A0S2DCD1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">OmpW family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Outer membrane protein, OmpW family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_04050</name>
        <name evidence="2" type="ORF">GLE_0671</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946204.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0671"/>
    <dbReference type="EnsemblBacteria" id="ALN56029">
        <property type="protein sequence ID" value="ALN56029"/>
        <property type="gene ID" value="GLE_0671"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0671"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.660"/>
    <dbReference type="OMA" id="VGVGYYQ"/>
    <dbReference type="OrthoDB" id="2018542at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
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        <property type="entry name" value="OMPW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36920">
        <property type="entry name" value="PTHR36920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03922">
        <property type="entry name" value="OmpW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242275" evidence="1">
        <location>
            <begin position="24"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="210" mass="22061" checksum="B4E6A7A7C732159B" modified="2016-02-17" version="1">MIRFRHLTLAMLGALAFAPAAFAQDASTDSASGKRFAIVGGYALSQPTKNPQIGGVRTDVDGDGAPTLSASYFFNDNFAIEAWGSADKFGQRLNSNGGKIGSVDSQPVALSGQYHFRGADSIVRPFVGLGYYQANYSGETLRSGQRLGVDDAKGGIATAGVDLNINPTWFARADVRYMQGSKSDVKLDGVKVGEAELNPVTVGVGIGARF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCE5</accession>
    <name>A0A0S2DCE5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Lipid A biosynthesis lauroyltransferase</fullName>
            <ecNumber evidence="8">2.3.1.241</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Kdo(2)-lipid IV(A) lauroyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 9" type="primary">lpxL</name>
        <name evidence="10" type="ORF">FE772_04685</name>
        <name evidence="9" type="ORF">GLE_0801</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>alpha-Kdo-(2-&gt;4)-alpha-Kdo-(2-&gt;6)-lipid IVA + dodecanoyl-[ACP] = dodecanoyl-(Kdo)2-lipid IVA + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:28442"/>
            <dbReference type="Rhea" id="RHEA-COMP:9644"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:60365"/>
            <dbReference type="ChEBI" id="CHEBI:61524"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:65264"/>
            <dbReference type="EC" id="2.3.1.241"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Glycolipid biosynthesis; KDO(2)-lipid A biosynthesis; KDO(2)-lipid A from CMP-3-deoxy-D-manno-octulosonate and lipid IV(A): step 3/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the LpxL/LpxM/LpxP family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.241" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946307.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0801"/>
    <dbReference type="EnsemblBacteria" id="ALN56159">
        <property type="protein sequence ID" value="ALN56159"/>
        <property type="gene ID" value="GLE_0801"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0801"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.790"/>
    <dbReference type="OMA" id="WRIERWF"/>
    <dbReference type="OrthoDB" id="1106624at2"/>
    <dbReference type="UniPathway" id="UPA00030"/>
    <dbReference type="UniPathway" id="UPA00360">
        <property type="reaction ID" value="UER00485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008913">
        <property type="term" value="F:lauroyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036104">
        <property type="term" value="P:Kdo2-lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07984">
        <property type="entry name" value="LPLAT_LABLAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01942">
        <property type="entry name" value="Lipid_A_LpxL_LpxP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004960">
        <property type="entry name" value="LipA_acyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011920">
        <property type="entry name" value="Lipid_A_LpxL_LpxP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30606">
        <property type="entry name" value="PTHR30606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03279">
        <property type="entry name" value="Lip_A_acyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026649">
        <property type="entry name" value="MsbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02207">
        <property type="entry name" value="lipid_A_htrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="short sequence motif" description="HXXXXD motif" evidence="8">
        <location>
            <begin position="133"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW25073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="309" mass="34941" checksum="D4452D9D08250A40" modified="2016-02-17" version="1">MAEPALPPRPSLLSPRLWPMWLALAAMCAGARLPWGLQRRLGALIGAFALRAAGTRRRAAQVNLKLCFPEKSEAEREVLLRESFRDLGIGFFEFARAWWGGVEPMRRTVRIEGLELLDEVRAAGRGVLMVSGHFMTLEMCGRLMCDRLPLAGMYRKHRNPVMEWAVKRGRLRYAAAMFTNEEIRPAMRHLKQGGFLWYAPDQDMRGKDTVFAPFFGVPAATITATHQFARLAGCAVVPFFHRREGADYILRVGAPLPDFPSSDATADSARVNAQIEAMVRQAPSQYLWIHRRFKRRPAGMVSPYKKTEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCV8</accession>
    <name>A0A0S2DCV8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cyclic nucleotide-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FE772_05640</name>
        <name evidence="9" type="ORF">GLE_1008</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1008"/>
    <dbReference type="EnsemblBacteria" id="ALN56366">
        <property type="protein sequence ID" value="ALN56366"/>
        <property type="gene ID" value="GLE_1008"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1008"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.996"/>
    <dbReference type="OMA" id="FTANKGY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726638" evidence="6">
        <location>
            <begin position="32"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="80"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="7">
        <location>
            <begin position="309"/>
            <end position="868"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW25218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="870" mass="95264" checksum="1CEDABC896AAFF4F" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD65</accession>
    <name>A0A0S2DD65_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytochrome B561</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Cytochrome b</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_06225</name>
        <name evidence="5" type="ORF">GLE_1140</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1140"/>
    <dbReference type="EnsemblBacteria" id="ALN56498">
        <property type="protein sequence ID" value="ALN56498"/>
        <property type="gene ID" value="GLE_1140"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1140"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1125"/>
    <dbReference type="OMA" id="LHNNVAW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011577">
        <property type="entry name" value="Cyt_b561_bac/Ni-Hgenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01292">
        <property type="entry name" value="Ni_hydr_CYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="SSF81342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Ni_hydr_CYTB" evidence="4">
        <location>
            <begin position="9"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="190"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW25317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="228" mass="24719" checksum="567E39774005C4E8" modified="2016-02-17" version="1">MTLKNTADRWGAVSQSLHWLIVLLIAAIAVIGLTMTDMSNGPSKIKIYALHKSLGLTLLALVVARLLWRVYAGAPGPVAGTPHWQERIASLTHWALYALMFALPLSGWLFNSTAGYPLQYFGLFNLPKLAARNEELAQLTRTLHETGFWVLLALVLAHAAAAFYHHLFQNDATLTRMLPGGRRTYDALADADAANGHGPSSADDRSQLPPTHPPTASAPASPENRNAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDG9</accession>
    <name>A0A0S2DDG9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0301 protein BV903_16320</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_16320</name>
        <name evidence="3" type="ORF">GLE_1177</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">B25</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0301 (AlgH) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000043">
        <property type="protein sequence ID" value="OPD62844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946572.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000053.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1177"/>
    <dbReference type="EnsemblBacteria" id="ALN56535">
        <property type="protein sequence ID" value="ALN56535"/>
        <property type="gene ID" value="GLE_1177"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62844">
        <property type="protein sequence ID" value="OPD62844"/>
        <property type="gene ID" value="BV903_16320"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1177"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1162"/>
    <dbReference type="OMA" id="IYWGGDF"/>
    <dbReference type="OrthoDB" id="1736059at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00758">
        <property type="entry name" value="UPF0301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003774">
        <property type="entry name" value="UPF0301"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30327">
        <property type="entry name" value="PTHR30327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02622">
        <property type="entry name" value="DUF179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD62844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="188" mass="19905" checksum="0BD2A1725426EA04" modified="2016-02-17" version="1">MTVMPTPLANQVLIALPALADTNFSRSVALICQHDDDGAMGIVVNRPSEYTLGEVFGQMGVEGGDEALRAQIVLAGGPVHPERGFVLHDGGTRWDSTLAIADDLFLTTSRDILEAMAKGEGPDHAIVALGCAGWGSGQLEHEITENDWLTAPADAELLFQLPLDARWHAAAGRIGVDFAHLADYAGHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDH6</accession>
    <name>A0A0S2DDH6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphonate metabolism transcriptional regulator PhnF</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Phosphonates metabolism transcriptional regulator PhnF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">phnF</name>
        <name evidence="4" type="ORF">FE772_06555</name>
        <name evidence="3" type="ORF">GLE_1208</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946597.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1208"/>
    <dbReference type="EnsemblBacteria" id="ALN56565">
        <property type="protein sequence ID" value="ALN56565"/>
        <property type="gene ID" value="GLE_1208"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1208"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1193"/>
    <dbReference type="OMA" id="PMLLLHR"/>
    <dbReference type="OrthoDB" id="1775418at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012702">
        <property type="entry name" value="CP_lyase_PhnF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011663">
        <property type="entry name" value="UTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07702">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00866">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02325">
        <property type="entry name" value="C_P_lyase_phnF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="2">
        <location>
            <begin position="39"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="272" mass="30138" checksum="29EFCFB8F5F5177E" modified="2016-02-17" version="1">MTSPAAAKRAVAEQAAGERPNPVPTPEPNPEPTQRDAAMPLWQQIETALLKDIRAGLLSEGDKLPSAFDLAKRFGVNRHTVRRAIEALEERGFLRTETGRGSFVQEHPYHYPIGRRTRFGKAMHDLNVESRYRLIESGTQAPPRLVARSLGLLAGERVHRVVYSSEVEGRTVDHSEAWFPAARFPGLDKVFADKLSVTRTLAEFGVRDYLRKHTAVMARLPAAEVARVLGQSTRRPVLCVHSLNVDTQGAPVQFGVTSFAGDWVQLMVTNEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDZ2</accession>
    <name>A0A0S2DDZ2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_07410</name>
        <name evidence="2" type="ORF">GLE_1399</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56756">
        <property type="protein sequence ID" value="ALN56756"/>
        <property type="gene ID" value="GLE_1399"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1399"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1381"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="357" mass="38955" checksum="0491248EF3E20736" modified="2016-02-17" version="1">MPRRIQAWILESHSAAADFAQFFKDGGVIQGQSGVTLPYYSPLEPPRILVDDSQWRSLQANDAPAWPQRHLFGTLAHEIGHHRYNTGSVPFHGRTGEEYVQYRAGLEAQAIFNAFPIFKELEGQPEFAGGKPFGSIGYLNEVELGSLYGEWKAGRLRDAEAVERIAAKVADAPYTLARPPQDMDGNGAIAHRDAYLRDYARYIEPKLQPQSSTDPAAAPLGPHDAALLDRLRAQVRELDRLAGKGWDEQSERLSASALVMAKECGFTARDELRLAFNRRSDDFAAGTLLHLARQGANASPDPYANRAHMPVAEALAVPAAERCEQARAVEVAQAQAAQPQAVCAPDDPGRAAAKLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE49</accession>
    <name>A0A0S2DE49_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAGPA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_07775</name>
        <name evidence="3" type="ORF">GLE_1480</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946809.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1480"/>
    <dbReference type="EnsemblBacteria" id="ALN56837">
        <property type="protein sequence ID" value="ALN56837"/>
        <property type="gene ID" value="GLE_1480"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1480"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1461"/>
    <dbReference type="OMA" id="QSGPMLI"/>
    <dbReference type="OrthoDB" id="1587976at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018711">
        <property type="entry name" value="NAGPA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09992">
        <property type="entry name" value="NAGPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242290" description="NAGPA domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="NAGPA" evidence="2">
        <location>
            <begin position="69"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="239" mass="26701" checksum="8E4D3E05B008ADBF" modified="2016-02-17" version="1">MRRAAACFCLALASLLGLPAAAREPRYTVLRVDTRSQPLALYWDDERGRPFHRFKTLDAWLRARGQRLRLAMNAGMFEPDYSPVGLFVADGRERAPLNLRDGDGNFYLKPNGVFLLDRDGKPRVIEASRYPGFADGARLATQSGPLLVAGGRIHPALDPQSRSRHRRNGVGVKGDEVIWAVSDDKVSLYEFARYFREELGCQDALYLDGTLSSLYAPQLKRADRRGKLGPILAVTEPLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE50</accession>
    <name>A0A0S2DE50_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD(P)-dependent alcohol dehydrogenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Oxidoreductase, zinc-binding dehydrogenase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_07300</name>
        <name evidence="2" type="ORF">GLE_1377</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946729.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1377"/>
    <dbReference type="EnsemblBacteria" id="ALN56734">
        <property type="protein sequence ID" value="ALN56734"/>
        <property type="gene ID" value="GLE_1377"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1377"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1359"/>
    <dbReference type="OMA" id="RDLMFAR"/>
    <dbReference type="OrthoDB" id="884088at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="10"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="338" mass="35164" checksum="BA5E72DEAB352364" modified="2016-02-17" version="1">MKAYRIRAGRGIDSLALAEEAPAPLGAGQVRLRVRAVSLNFRDLMVADGRYPAGGDRAVIPASDAVAEVIELGPGATRWALGDRVATSFFPHWHAGAASAHATREPFGADADGVLAEQIVVSQESVFAVPAHLDDAQAATLTCAGVTAWNALFVEAGLRPGQSVLLLGTGGVSIWGLQLAKAAGLRAIVTSSSDAKLERARALGADETINYRSHPEWQDEVLRLTAGDGVDAVLEVGGAGTLARSLRAAAMNGTVAIIGGVSGFAGEFDPFALIMGAKRLSGIYVGSRGMGEDLARFVGVNRIAPVVDRMFAFEQAGEAYRYLESGSHFGKVVIRVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE85</accession>
    <name>A0A0S2DE85_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein HflK</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hflK</name>
        <name evidence="9" type="ORF">FE772_07930</name>
        <name evidence="8" type="ORF">GLE_1512</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">HflC and HflK could encode or regulate a protease.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">HflC and HflK may interact to form a multimeric complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the band 7/mec-2 family. HflK subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946837.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1512"/>
    <dbReference type="EnsemblBacteria" id="ALN56869">
        <property type="protein sequence ID" value="ALN56869"/>
        <property type="gene ID" value="GLE_1512"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1512"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1493"/>
    <dbReference type="OMA" id="WNEPGGN"/>
    <dbReference type="OrthoDB" id="577287at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03404">
        <property type="entry name" value="SPFH_HflK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010201">
        <property type="entry name" value="HflK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_HflKC_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327:SF2">
        <property type="entry name" value="PTHR43327:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01933">
        <property type="entry name" value="hflK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="7">
        <location>
            <begin position="61"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="335"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="344"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN56869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW25604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="373" mass="40939" checksum="55F5465E37C8E2E6" modified="2016-02-17" version="1">MAWNTPGSDNSGDNRPSRQRKPQGRGLDALIDSARGLFGGGGAGGILRWVGVLVALWLAFNCFVLVTEQERGVVLRFGTFSRVLQPGPHFKLPWPVESVQKVNATQSKAYSENVPVLTRDGNMVNVEINVQYRIESPRQYLFGSRAPEEVLKQAAQSAVREQIGRSDLDTVLGARSVLTTQVRQRLQSSLKDYETGLTVTELNLPNARPPDEVKDAFDEAQRANADKSTAINEAQAYAKKIVPEARGDAQRIRTTAEGYKTSIVARAQGDAARFSLLVEQYKGAPEVTRKRLWLDAVQEVLSNNRKIVGGDSRQILQIPLTDRGGVQVTPGPVSVPLAQPELLPSVTATDSSRSSIPYSGRPERPKTRDEVMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEE0</accession>
    <name>A0A0S2DEE0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable septum site-determining protein MinC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 10" type="primary">minC</name>
        <name evidence="10" type="ORF">GLE_1576</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts with MinD and FtsZ.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the MinC family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1576"/>
    <dbReference type="EnsemblBacteria" id="ALN56933">
        <property type="protein sequence ID" value="ALN56933"/>
        <property type="gene ID" value="GLE_1576"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1576"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1556"/>
    <dbReference type="OMA" id="RRDPLWG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051302">
        <property type="term" value="P:regulation of cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901891">
        <property type="term" value="P:regulation of cell septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00267">
        <property type="entry name" value="MinC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013033">
        <property type="entry name" value="MinC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036145">
        <property type="entry name" value="MinC_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007874">
        <property type="entry name" value="MinC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005526">
        <property type="entry name" value="Septum_form_inhib_MinC_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34108">
        <property type="entry name" value="PTHR34108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03775">
        <property type="entry name" value="MinC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05209">
        <property type="entry name" value="MinC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63848">
        <property type="entry name" value="SSF63848"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01222">
        <property type="entry name" value="minC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 6" id="KW-0132">Cell division</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0717">Septation</keyword>
    <feature type="domain" description="MinC_N" evidence="9">
        <location>
            <begin position="4"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="MinC_C" evidence="8">
        <location>
            <begin position="160"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="119"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN56933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="262" mass="27601" checksum="57AE9CCDFB61158B" modified="2016-02-17" version="1">MDYEQAGELKIGQVGIANLRIRSLDVPRLVEEMRSRVQRAPNMFGRAAVVIDFGGLSHAPDIASAQALLDGLRAAGVLPVALAYGTSEIEKLSQALGLPLLAKFRASYERADGVAVAEAAAPPRREAPAPAPAAEPARAPRPPAGAPPVAQASSVGMIQSAPVRSGQQIYADNRDLTVLTTVGAGAEVIADGSVHIYGPLRGRALAGAQGNAKARIFCREFHAELVAIAGRYKVLEDIPKELRGKPVQVWLEDEQIKIAALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEJ0</accession>
    <name>A0A0S2DEJ0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">DNA repair protein RecO</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4 5">Recombination protein O</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">recO</name>
        <name evidence="7" type="ORF">GLE_1712</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Involved in DNA repair and RecF pathway recombination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the RecO family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946996.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1712"/>
    <dbReference type="EnsemblBacteria" id="ALN57067">
        <property type="protein sequence ID" value="ALN57067"/>
        <property type="gene ID" value="GLE_1712"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1712"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1690"/>
    <dbReference type="OMA" id="TALFCAM"/>
    <dbReference type="OrthoDB" id="1758685at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00201">
        <property type="entry name" value="RecO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022572">
        <property type="entry name" value="DNA_rep/recomb_RecO_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003717">
        <property type="entry name" value="RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042242">
        <property type="entry name" value="RecO_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33991">
        <property type="entry name" value="PTHR33991"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02565">
        <property type="entry name" value="RecO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11967">
        <property type="entry name" value="RecO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00613">
        <property type="entry name" value="reco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_rep/recomb_RecO_N" evidence="6">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="249" mass="27450" checksum="7E5A8660A77DC854" modified="2016-02-17" version="1">MRLTAEPAYILHVRPWRETSVLVEALSEQHGRIGLVARGVQGPKKQVLRAALQPFQHVRLDALLRGELARLATAEAIDAAPRLHGDAALAGFYVNELLLRLVPRGDPFAELYELYGRTRARLDGPHLAWTLRRFERDLLDALGSGLDWSADADGAPIDPAARYRLDPEQGARRLLSDRGHGERSAAATGRALLALAEDRQPEPSDLPGLRHALRSVLVHHLGPRGLKSWEMMADLARASRPAAVRDDNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEU2</accession>
    <name>A0A0S2DEU2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">7-methyl-GTP pyrophosphatase</fullName>
            <shortName evidence="3">m(7)GTP pyrophosphatase</shortName>
            <ecNumber evidence="3">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">maf</name>
        <name evidence="5" type="ORF">FE772_08735</name>
        <name evidence="4" type="ORF">GLE_1685</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + N(7)-methyl-GTP = diphosphate + H(+) + N(7)-methyl-GMP</text>
            <dbReference type="Rhea" id="RHEA:58744"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58285"/>
            <dbReference type="ChEBI" id="CHEBI:87133"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Maf family. YceF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946976.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1685"/>
    <dbReference type="EnsemblBacteria" id="ALN57041">
        <property type="protein sequence ID" value="ALN57041"/>
        <property type="gene ID" value="GLE_1685"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1685"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1663"/>
    <dbReference type="OMA" id="CAGSFKA"/>
    <dbReference type="OrthoDB" id="1469203at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047429">
        <property type="term" value="F:nucleoside-triphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00555">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00528">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003697">
        <property type="entry name" value="Maf-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213">
        <property type="entry name" value="PTHR43213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02545">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006305">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00172">
        <property type="entry name" value="maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="191" mass="20520" checksum="D71E212014462879" modified="2016-02-17" version="1">MTPLILASTSVYRRELLARLRLDFDVARPETDETPQPGEAPAALAWRLAEAKAAAVAAQRPGAWVIGSDQVAEFDGRPIGKPGGRDQAIAQLSAMSGREVRFCTGVCVLRDGEAGLSELDVTVVRFRELALAEIERYVDAERPFDCAGSFKSEGLGIALFEAIESRDPTALVGLPLIATARLLRRAGYALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEX3</accession>
    <name>A0A0S2DEX3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA polymerase sigma factor RpoE</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">RNA polymerase sigma-E factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpoE</name>
        <name evidence="6" type="ORF">BV903_13250</name>
        <name evidence="8" type="ORF">D9T17_18760</name>
        <name evidence="7" type="ORF">FE772_08810</name>
        <name evidence="5" type="ORF">GLE_1703</name>
    </gene>
    <organism evidence="5 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 9">C3</strain>
        </source>
    </reference>
    <reference evidence="6 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">OH11</strain>
        </source>
    </reference>
    <reference evidence="7 12" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 12">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000034">
        <property type="protein sequence ID" value="OPD63395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000045">
        <property type="protein sequence ID" value="ROU05456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946989.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1703"/>
    <dbReference type="EnsemblBacteria" id="ALN57058">
        <property type="protein sequence ID" value="ALN57058"/>
        <property type="gene ID" value="GLE_1703"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63395">
        <property type="protein sequence ID" value="OPD63395"/>
        <property type="gene ID" value="BV903_13250"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1703"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1681"/>
    <dbReference type="OMA" id="LVDMQGY"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014286">
        <property type="entry name" value="RNA_pol_sigma70_RpoE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02939">
        <property type="entry name" value="RpoE_Sigma70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="3">
        <location>
            <begin position="26"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="4">
        <location>
            <begin position="133"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD63395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW28685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ROU05456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="206" mass="23970" checksum="1DE950405194B3AD" modified="2016-02-17" version="1">MADNELLDQELVRRVQRGDSAAFDALVRKYQHRITALIGRYIPDWSECQDVAQETFIRAYRAMANFRGDAQFYTWLHRIAVNTAKNYLVAQNRRPPTDDIDAGDAEQFETGVRLRDTDTPEHELLRQEIERTVMRVVDSLPEELRSAITLREVDGLSYEEIAQKMNCPIGTVRSRIFRAREAIDTELRPLLDNQDQGTHRTRERAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEX9</accession>
    <name>A0A0S2DEX9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cysteine hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Isochorismatase family protein</fullName>
            <ecNumber evidence="2">3.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_13535</name>
        <name evidence="4" type="ORF">FE772_09120</name>
        <name evidence="2" type="ORF">GLE_1771</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.-.-.-" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000034">
        <property type="protein sequence ID" value="OPD63444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947039.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1771"/>
    <dbReference type="EnsemblBacteria" id="ALN57125">
        <property type="protein sequence ID" value="ALN57125"/>
        <property type="gene ID" value="GLE_1771"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63444">
        <property type="protein sequence ID" value="OPD63444"/>
        <property type="gene ID" value="BV903_13535"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1771"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1746"/>
    <dbReference type="OMA" id="RDHYVEK"/>
    <dbReference type="OrthoDB" id="1442962at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="23"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="203" mass="21485" checksum="D7419E6E80751675" modified="2016-02-17" version="1">MNHPTIRTIAGAAAPQSLPAGKTALLVIDFQNEYFSGRMPIPDGAQALANARRLIDRADANGIVVYHVQHVTPPGTPIFAEDGDSVRFHADLQPAAHHRVVRKSSVSVFPTTDLHRQLQRDGIRSLLIAGLMTHACVAGAARDAVPLGYEVIVASDACATRDLDTGEGRVLPHADLHRAALASIDDTFGAILSTEAVLALPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEY2</accession>
    <name>A0A0S2DEY2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1775</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57129">
        <property type="protein sequence ID" value="ALN57129"/>
        <property type="gene ID" value="GLE_1775"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1775"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1750"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="63" mass="7139" checksum="C938B4155CF4F993" modified="2016-02-17" version="1">MLPLDAYLELQKFHDELVGIADTIDPAAAPLPGVRKPEQSRRRALARVFRLWAQQIERSLVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEY8</accession>
    <name>A0A0S2DEY8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Anti sigma-E protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_1704</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946990.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1704"/>
    <dbReference type="EnsemblBacteria" id="ALN57059">
        <property type="protein sequence ID" value="ALN57059"/>
        <property type="gene ID" value="GLE_1704"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1704"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1682"/>
    <dbReference type="OMA" id="FTHPDTT"/>
    <dbReference type="OrthoDB" id="1759295at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016989">
        <property type="term" value="F:sigma factor antagonist activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16328">
        <property type="entry name" value="RseA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005572">
        <property type="entry name" value="Anti-sigma_E_RseA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036147">
        <property type="entry name" value="Anti-sigma_E_RseA_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03872">
        <property type="entry name" value="RseA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89069">
        <property type="entry name" value="SSF89069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="RseA_N" evidence="3">
        <location>
            <begin position="11"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="328" mass="33149" checksum="15E64B0DB9FA01D0" modified="2016-02-17" version="1">MTSTIHSGDDNETLSALFDGELDGDAARFAFKRLSHDGQWREACGRWQLCGDVLRRRAHGAAEPAPGFAATGFAERVAAAIAADAALQASQAAAAPPAQTEIKPRKAAGSRRGWIGGAALAASVAVAALFVARPFSDEAAGGVADPAQVAAQAAPGAAPAQPAAPAVPQPAPAQAPQALAAQAPATAETGLTSADASGIAAGAAVAVAELPRRLNERRSRGQSQRAAVRASERQTQEAPLQVAAAGAPMTAVADAGHANPFRPQSGETPAARPWPRAALPNYPSSSAYSASYGSSGLVSPSFYPFEPAQDASAARTRPPVQEPQPPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEZ5</accession>
    <name>A0A0S2DEZ5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nitrilase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1635</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1635"/>
    <dbReference type="EnsemblBacteria" id="ALN56992">
        <property type="protein sequence ID" value="ALN56992"/>
        <property type="gene ID" value="GLE_1635"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1635"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1615"/>
    <dbReference type="OMA" id="LVFPEYA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001110">
        <property type="entry name" value="UPF0012_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01227">
        <property type="entry name" value="UPF0012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="2">
        <location>
            <begin position="6"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="303" mass="32833" checksum="565D76C4525FEC1A" modified="2016-02-17" version="1">MTDSTIRVAVAKYAIGAPRDFAEFADKQAQWLSQARAGGAQLAVLPEYLSLELGATFGASTQGDLHASLVAIQQYHEAWLALFGLLARELRLHIVAGSFLYDHEGRGRYRNRSYAFAPDGGRLWQDKLQLTGFEKQAGVIEPGDALKTFDLAGERAGIAICYDIEFPLPVRAQCEAGARLLIAPSCTDTQAGATRVRVGCLARALENRAFVAQAVTAGEALWSPALDTNTGEAAVYAPMDAGLPADGVLATTRGHQRWAFADLDFAALEASRERAQVANDRDWAGQWKPAIARAQRTQWDEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF68</accession>
    <name>A0A0S2DF68_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Poly-beta-1,6-N-acetyl-D-glucosamine synthase</fullName>
            <shortName evidence="3">Poly-beta-1,6-GlcNAc synthase</shortName>
            <ecNumber evidence="3">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pgaC</name>
        <name evidence="5" type="ORF">FE772_09570</name>
        <name evidence="4" type="ORF">GLE_1869</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947108.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1869"/>
    <dbReference type="EnsemblBacteria" id="ALN57221">
        <property type="protein sequence ID" value="ALN57221"/>
        <property type="gene ID" value="GLE_1869"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1869"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1840"/>
    <dbReference type="OMA" id="RNRWAEG"/>
    <dbReference type="OrthoDB" id="724641at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008375">
        <property type="term" value="F:acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043708">
        <property type="term" value="P:cell adhesion involved in biofilm formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023853">
        <property type="entry name" value="PGA_PgaC/IcaA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03937">
        <property type="entry name" value="PgaC_IcaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="306"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="375"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="419" mass="48163" checksum="3BB5A1B587C0B2A4" modified="2016-02-17" version="1">MNPTTSPVLTALFQFAFFYPIVMSFFWIAGGLYYYFRRERASRGRTDPPPLDAAPFVSILIPCHNEGDHVHETLGAALAQRYPDFEVIAINDGSRDDTGEQLNRLAAIHPRLRVVHLDRNLGKANAMRMGALAARSEYLVCIDGDALLDEYATHWMVWHLISGARVGAVTGNPRIRNRSTLLGRLQVGEFSSIIGMIKRAQRVYGRIFTVSGVICAFRRSALHRIGYWSDSMVTEDIDISWRLQLDHWDIRYEPNAMCFILMPETLKGLWKQRLRWAQGGVEVLMRHSRDLFSWRKRRMWAVMAEYVASVAWAYIMALIMALWAIGLFVDLPPQLRVTTLLPSWHGVILALICLLQFAASIIIDRRYETGVGRNYYWMIWYPMAYWLLSFFTTVTAVPKALLKRRGTRATWVSPDRGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFH0</accession>
    <name>A0A0S2DFH0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1968</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57319">
        <property type="protein sequence ID" value="ALN57319"/>
        <property type="gene ID" value="GLE_1968"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1968"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1933"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="37" mass="4025" checksum="4FB6E979F4D1E6FC" modified="2016-02-17" version="1">MRARFWWARCAGRRAGFGGNGRATAREGCLRGSGVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFK4</accession>
    <name>A0A0S2DFK4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1774</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57128">
        <property type="protein sequence ID" value="ALN57128"/>
        <property type="gene ID" value="GLE_1774"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1774"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1749"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="89" mass="10051" checksum="1B572C04926AF094" modified="2016-02-17" version="1">MLPLDAYLELQKFHDQLEGITDTIDPVLPNGECSIRLQSTAAMNKGPVTGAISKEILKQGVSARFLERKHFTPACRRDWSRPKIQIDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFL4</accession>
    <name>A0A0S2DFL4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1864</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57216">
        <property type="protein sequence ID" value="ALN57216"/>
        <property type="gene ID" value="GLE_1864"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1864"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1835"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="52" mass="6322" checksum="12EA0992A65689F8" modified="2016-02-17" version="1">MNINVYNLMFVVAVVGFFVVTIYFLYRFLRGRGKEFTISDWCKKVWDLFWGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFQ7</accession>
    <name>A0A0S2DFQ7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">YcII domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_10255</name>
        <name evidence="4" type="ORF">GLE_2020</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YciI family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57370">
        <property type="protein sequence ID" value="ALN57370"/>
        <property type="gene ID" value="GLE_2020"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2020"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1985"/>
    <dbReference type="OMA" id="GADDYGM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242301" evidence="2">
        <location>
            <begin position="23"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="YCII" evidence="3">
        <location>
            <begin position="66"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="175" mass="18035" checksum="F4EDDA4070BDD8AD" modified="2016-02-17" version="1">MATKTMKAMACAVLALTGAATAAQAAAAAAAAKPAQPAPQAAATAYDPALAARTGADAQGMRKYVLVILKTGPNPMPDGEQRKAMFAGHFANMERLAKAGKLALAGPFGKDPDGWRGLFVLAVDDVEQARALVASDPAVAHGEFVAEYHRWYGSAATMLIPELHEKLQAPAAPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG28</accession>
    <name>A0A0S2DG28_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoglycerate mutase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_11295</name>
        <name evidence="1" type="ORF">GLE_2241</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947392.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2241"/>
    <dbReference type="EnsemblBacteria" id="ALN57590">
        <property type="protein sequence ID" value="ALN57590"/>
        <property type="gene ID" value="GLE_2241"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2241"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2206"/>
    <dbReference type="OMA" id="GHNIDIW"/>
    <dbReference type="OrthoDB" id="1293048at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046537">
        <property type="term" value="F:2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004456">
        <property type="entry name" value="Pglycerate_mutase_ApgM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016631">
        <property type="entry name" value="Regulatory_RpfE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31209">
        <property type="entry name" value="PTHR31209"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015283">
        <property type="entry name" value="Regulatory_RpfE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="318" mass="34881" checksum="F6AC07E2B8EA576B" modified="2016-02-17" version="1">MNRVDLLLPARERFGGQRLGEALGLRFGRADRTVEAADPAARVFDLLPRGWPVAAATRQRDAGDAAQGAWLRADPVYVRPDINGARLLAYGRALSLSERDSAALLPALKPLFGDAGFPIDAPAPDRWYVALPRETRLPRFVSPEQALGEDMFQHLPEGEGAEGRRWRALLSEAQVVLHNHPHNLARAEAGLAPVNSLWFWGAGALPDRVRCDYAGVYSDDEALTAFGAQAGIASGPLPHAWTEPAGEGAAVEGARLFDLRAQRDLALIQRDWLQPLAQALDRGALARVAALCADGERFELARSQRWRFWRKPLRSLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG99</accession>
    <name>A0A0S2DG99_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA-deoxyinosine glycosylase</fullName>
            <ecNumber evidence="3">3.2.2.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_10875</name>
        <name evidence="2" type="ORF">GLE_2156</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.2.15" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947323.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2156"/>
    <dbReference type="EnsemblBacteria" id="ALN57506">
        <property type="protein sequence ID" value="ALN57506"/>
        <property type="gene ID" value="GLE_2156"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2156"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2119"/>
    <dbReference type="OMA" id="QQYYAHP"/>
    <dbReference type="OrthoDB" id="2034230at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033958">
        <property type="term" value="F:DNA-deoxyinosine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026353">
        <property type="entry name" value="Hypoxan-DNA_Glyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04274">
        <property type="entry name" value="hypoxanDNAglyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="1">
        <location>
            <begin position="7"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="173" mass="18484" checksum="FB5682D6C56A741E" modified="2016-02-17" version="1">MLIHSFPPLEVPDARALVLGSMPGAASLAAGRYYAHPHNRFWPIMGELVGAGPVLDFPQRVAALAAAGIALWDVLAQCEREGSLDSAIRDDTAVPNDIAGFLARHPRVGTVLFNGAKAEQSFRRFIAPGLARPDLTLVRLPSTSPANASQDAAMKLEAWRQALRAAGVRLREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGD2</accession>
    <name>A0A0S2DGD2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Lysine--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Lysyl-tRNA synthetase</fullName>
            <shortName evidence="7">LysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">lysS</name>
        <name evidence="11" type="ORF">FE772_11470</name>
        <name evidence="10" type="ORF">GLE_2278</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7 8">
            <text>ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys)</text>
            <dbReference type="Rhea" id="RHEA:20792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9696"/>
            <dbReference type="Rhea" id="RHEA-COMP:9697"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78529"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7 8">Binds 3 Mg(2+) ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.6" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947417.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2278"/>
    <dbReference type="EnsemblBacteria" id="ALN57627">
        <property type="protein sequence ID" value="ALN57627"/>
        <property type="gene ID" value="GLE_2278"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2278"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2243"/>
    <dbReference type="OMA" id="EIFGEKC"/>
    <dbReference type="OrthoDB" id="63621at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004824">
        <property type="term" value="F:lysine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006430">
        <property type="term" value="P:lysyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00775">
        <property type="entry name" value="LysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04322">
        <property type="entry name" value="LysRS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00252">
        <property type="entry name" value="Lys_tRNA_synth_class2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002313">
        <property type="entry name" value="Lys-tRNA-ligase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044136">
        <property type="entry name" value="Lys-tRNA-ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018149">
        <property type="entry name" value="Lys-tRNA-synth_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00982">
        <property type="entry name" value="TRNASYNTHLYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00499">
        <property type="entry name" value="lysS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="9">
        <location>
            <begin position="185"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN57627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW26196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="505" mass="56910" checksum="067833FC82D459BC" modified="2016-02-17" version="1">MTDETQQPSIDENHLIAERRAKLTALRGEGIAFPNDFRRGDYAGDLHALYADADLWTQEALDAKAHRVAVAGRILLKRVMGKASFVQIQDESGRLQLFLQANALGDTYDKFKGWDVGDIVAAEGALTRTKTGELSVKAESLRLLTKALRPLPDKFHGLADVEQRYRQRYVDLIVSPDSREVFVKRSKIIRAMRAWLDARRFLEVETPMMHYIPGGATAKPFTTHHNALDLQLYLRVAPELYLKRLTVGGLERVYEINRNFRNEGVSTRHNPEFTMLELYEAYATYTEIMDLTEAVIRHAANDVLRTTQVEWDGNAIDLGPAFRRWSMTDAVLEHNPQIKREELRDLAAMRAHCARLKVAVKPSYGWGKLLLEIFEKTVEHTLIQPTFITDHPVEVSPLARANDLDPELTDRFELFVGGKELANGFSELNDPEDQAARFQAQVAQKDGGDDEAMHFDADYIRALEVGLPPTGGLGIGIDRLVMLLTGSSSIRDVLLFPYMRPEAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGE7</accession>
    <name>A0A0S2DGE7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_2120</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2120"/>
    <dbReference type="EnsemblBacteria" id="ALN57470">
        <property type="protein sequence ID" value="ALN57470"/>
        <property type="gene ID" value="GLE_2120"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2120"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2084"/>
    <dbReference type="OMA" id="TTIRCHY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0697">Rotamase</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594993" description="Peptidyl-prolyl cis-trans isomerase" evidence="5">
        <location>
            <begin position="33"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="6">
        <location>
            <begin position="73"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="172" mass="18096" checksum="2C5F91E1AF4EBD7D" modified="2016-02-17" version="1">MFRPVAPRSAASAAARALPLALLLAAAAPMLAGCQRPAEQEQAAAAPKVMHGRIAQFEMIDQRVGTGAVAQPGQEAIVQYTGWFYDETAPNKRGSKFDSSYDRNGRPFSFLLGAGRVIRGWDDGVAGMRVGGKRVLMVPPDLAYGKDGAGGGAIPPDASLVFEVELLGLEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGL4</accession>
    <name>A0A0S2DGL4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_2235</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2235"/>
    <dbReference type="EnsemblBacteria" id="ALN57584">
        <property type="protein sequence ID" value="ALN57584"/>
        <property type="gene ID" value="GLE_2235"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2235"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2200"/>
    <dbReference type="OMA" id="LTHWVAD"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024618">
        <property type="entry name" value="DUF3857"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12969">
        <property type="entry name" value="DUF3857"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595104" evidence="2">
        <location>
            <begin position="27"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3857" evidence="4">
        <location>
            <begin position="70"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="TGc" evidence="3">
        <location>
            <begin position="287"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="650" mass="70547" checksum="4789A72556075891" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGS9</accession>
    <name>A0A0S2DGS9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Hydrolase, alpha/beta fold family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_12555</name>
        <name evidence="2" type="ORF">GLE_2498</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2498"/>
    <dbReference type="EnsemblBacteria" id="ALN57847">
        <property type="protein sequence ID" value="ALN57847"/>
        <property type="gene ID" value="GLE_2498"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2498"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2461"/>
    <dbReference type="OMA" id="DGWRPVF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="45"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="306" mass="33253" checksum="7CBBC58C5AB8385F" modified="2016-02-17" version="1">MTVSMSDPSAVPAGAAPVREAGMRVQVGDGLGVHVRTWGERPPSLLLVHGFSHGGFVWRSLAAAMPEYGLAAPDLRGHGDSDHDPSRRYSIAAHVSDLIEVARALDLRDYLLVGHSLGASVATLAAQRLPRPPRAVVLVDGGPGLSPTASAHIREEFLRLKFRYRSPDEYLEYLQATMPLVPPPLLQALAVDALERLGPEEFRLKADRALGYQDQAASVEDELWQGLREIRVPLLLVRGAASALCGKRWCEEFSARVPQAEVESVQRAGHAVMLDNPSRFNALLRQYAAQRLAPRGAAPLHVQEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGW5</accession>
    <name>A0A0S2DGW5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Radical SAM domain protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Radical SAM protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_12705</name>
        <name evidence="7" type="ORF">GLE_2530</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947612.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2530"/>
    <dbReference type="EnsemblBacteria" id="ALN57879">
        <property type="protein sequence ID" value="ALN57879"/>
        <property type="gene ID" value="GLE_2530"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2530"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2492"/>
    <dbReference type="OMA" id="RCCGLMG"/>
    <dbReference type="OrthoDB" id="1172757at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023885">
        <property type="entry name" value="4Fe4S-binding_SPASM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13186">
        <property type="entry name" value="SPASM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW26396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="390" mass="44622" checksum="8C03E5A9ACBBF3A4" modified="2016-02-17" version="1">MQPQSSAPLDRHAFERLKQSIRNKAESSRGLRRDPGYATAIPEEIGIKLNNRCNLRCTHCFEWNEDGYHHDMIHSTVRDEVPIELLRSVLEQTRGASSKLFLWGGEPLIYSQFGKMAELIAAEGRWTTICTNAITTERRYDDLVKMSANLEFLASLEGFEQENDAIRGKGTYAKVIKSVDLLLDSKRRGEYRGEVAVQLTINDSMIGRLYEFVEHFERVGVDSVHLTFPWYISGETAGEMDRYVGEHFPWAMPKLDFLKPSWHSFTYSLSEEHHRALADEMARVSARVWNTRVRFKPALEDDELLDFIRGSSRPGQRRSQCLAITNRIDILPNGDVSSCKFFPEFSMGNLKDASLQEVWHGERFGEVRKTLACGLMPACSKCVLLYLNGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH51</accession>
    <name>A0A0S2DH51_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_18715</name>
        <name evidence="3" type="ORF">FE772_13320</name>
        <name evidence="1" type="ORF">GLE_2658</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000052">
        <property type="protein sequence ID" value="OPD62389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947710.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000052.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2658"/>
    <dbReference type="EnsemblBacteria" id="ALN58006">
        <property type="protein sequence ID" value="ALN58006"/>
        <property type="gene ID" value="GLE_2658"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62389">
        <property type="protein sequence ID" value="OPD62389"/>
        <property type="gene ID" value="BV903_18715"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2658"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2617"/>
    <dbReference type="OMA" id="GNTLIWA"/>
    <dbReference type="OrthoDB" id="1710764at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD62389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="103" mass="11173" checksum="8BB180DC6B8367F4" modified="2016-02-17" version="1">MTQAFEHEQWWLATLGRTAIWARLRVLEAGTAEVLDSDGNTLPYDSEDTARAALMDAEFVQYDGLDEDDAAARGFALGELAPPQAGSDAALAALMTQQLPPRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH97</accession>
    <name>A0A0S2DH97_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Putative fluoride ion transporter CrcB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10 11" type="primary">crcB</name>
        <name evidence="11" type="ORF">GLE_2625</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Important for reducing fluoride concentration in the cell, thus reducing its toxicity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the CrcB (TC 9.B.71) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2625"/>
    <dbReference type="EnsemblBacteria" id="ALN57973">
        <property type="protein sequence ID" value="ALN57973"/>
        <property type="gene ID" value="GLE_2625"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2625"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2584"/>
    <dbReference type="OMA" id="FLMFESF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903425">
        <property type="term" value="F:fluoride transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00454">
        <property type="entry name" value="CrcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003691">
        <property type="entry name" value="CrcB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28259">
        <property type="entry name" value="PTHR28259"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02537">
        <property type="entry name" value="CRCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00494">
        <property type="entry name" value="crcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="91"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN57973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="128" mass="13080" checksum="A52055D4B974EA65" modified="2016-02-17" version="1">MSIFIGAGLGALLRWWLGLALNPLFPTVPMGTLAANALGGLLMGVLMAVFAQYETLPLALRLALTTGFLGGLTTFSTFSAETSGLLLRGEYGWAGAIVAAHVGASLLATLAGVMAVRGLFRWLAGAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHF3</accession>
    <name>A0A0S2DHF3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter, ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLE_2539</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2539"/>
    <dbReference type="EnsemblBacteria" id="ALN57888">
        <property type="protein sequence ID" value="ALN57888"/>
        <property type="gene ID" value="GLE_2539"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2539"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2500"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="17"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="337"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="373"/>
            <end position="380"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN57888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="604" mass="65012" checksum="997C8336EAD3AFD9" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHI2</accession>
    <name>A0A0S2DHI2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flavin-dependent oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">LLM class flavin-dependent oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_01595</name>
        <name evidence="4" type="ORF">FE772_12610</name>
        <name evidence="2" type="ORF">GLE_2509</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000003">
        <property type="protein sequence ID" value="OPD65715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947594.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2509"/>
    <dbReference type="EnsemblBacteria" id="ALN57858">
        <property type="protein sequence ID" value="ALN57858"/>
        <property type="gene ID" value="GLE_2509"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65715">
        <property type="protein sequence ID" value="OPD65715"/>
        <property type="gene ID" value="BV903_01595"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2509"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2472"/>
    <dbReference type="OMA" id="MIDESMY"/>
    <dbReference type="OrthoDB" id="1434838at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="1">
        <location>
            <begin position="54"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD65715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="421" mass="48521" checksum="D677090B04846FEE" modified="2016-02-17" version="1">MKVSMFHLMPLRDLPADFEQRHRSVWVDVPWHELTTPERVGRFYNQSLDELIYAARCGIDGVCVNEHHQNAYGMMPSPNLMGAILARQTAELDVACIQLGATLPNTQPPIRIAEEYAMLDCISGGRIVAGMPLGTPFDANYCYGITPLEQRERYYEAHDLILKAWREREPFAWNGKYTQLPMVNLWPRPMQDPHPPIWVPGSGSLSTWEFTARHDYCYCFLSYHGIRFGKSVMDKFWEFSARNGHDANPYRTGFLQLVAVAETDEQAERDYYEHIRYFYDKTQHVAPEFTPPGHQDYRSMVNTIRNQVSQVNSVRSRIPQFKFKDFVDNQLVIAGSPATVREQLAESVRQLRVGNLMVLLQIGSMPHELTLKNIRLFCSEVLPHLRGIWDDEGWENRWWPQRLRGARNAPAAPAQPGWVGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHP4</accession>
    <name>A0A0S2DHP4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2677</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58025">
        <property type="protein sequence ID" value="ALN58025"/>
        <property type="gene ID" value="GLE_2677"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2677"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2636"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="140" mass="15450" checksum="F8C45FA0D1B3195A" modified="2016-02-17" version="1">MHAPPPLDPQDLLATLRDWAERIADADGKAIDDYLDRRDREPFDGQWTRADAALQSHKRRLDPQRVQRAQAESAQLRQAAFVAVMQAAGHAELAAYLADDAALIYESEVLGLCSDWVRALHRSYLHVAEAPAPGPLESAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHS3</accession>
    <name>A0A0S2DHS3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Isochorismatase</fullName>
            <ecNumber evidence="3">3.3.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_2622</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + isochorismate = (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:11112"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29780"/>
            <dbReference type="ChEBI" id="CHEBI:58764"/>
            <dbReference type="EC" id="3.3.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
        <text evidence="4">Binds 1 phosphopantetheine covalently.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Siderophore biosynthesis.</text>
    </comment>
    <dbReference type="EC" id="3.3.2.1" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2622"/>
    <dbReference type="EnsemblBacteria" id="ALN57970">
        <property type="protein sequence ID" value="ALN57970"/>
        <property type="gene ID" value="GLE_2622"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2622"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2581"/>
    <dbReference type="OMA" id="RDIKPFF"/>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008908">
        <property type="term" value="F:isochorismatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016291">
        <property type="entry name" value="Isochorismatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001111">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01398">
        <property type="entry name" value="ISCHRISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="7">
        <location>
            <begin position="214"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4 5">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001111-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN57970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="292" mass="32490" checksum="0844C8403CE4F231" modified="2016-02-17" version="1">MTIPKIATYPMPGPQQWPSNRVDWRPEPARAVLLIHDLQEYFLAFYDQTQAPVPQLLENVRALRDACDDAGVPVVYTAQPPVQSARQRGLLQPWWGPGITAQPKLAPVAAPIAPRPHDTVLTKWRYSAFVSSDLRERMREQGRDQLIVCGIYAHIGCMMTAADAFMHDIQPFLVADALADFSAQEHQMALDYVSRRCGVVLGRADCAQALADGAGLPASLTALRTELALIMERPLAEIGADDNPFEVGLDSIRMMTLLERWSARGERIGLVELAERGSVAQWWELIQQRRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHT0</accession>
    <name>A0A0S2DHT0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_12595</name>
        <name evidence="2" type="ORF">GLE_2506</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2506"/>
    <dbReference type="EnsemblBacteria" id="ALN57855">
        <property type="protein sequence ID" value="ALN57855"/>
        <property type="gene ID" value="GLE_2506"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2506"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2469"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="1">
        <location>
            <begin position="112"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="426" mass="47814" checksum="45D110FC00FCF626" modified="2016-02-17" version="1">MAAKEIARISRPDPERFLRDYVRTRTPVIITDLFAGQPIDAIRTIEDASAAFGGVPMHVQTEYAVAASSPETAVETTMTFDEYWAHVRANPDTALLCTEYEIPASIMRMFRLPEFCLAQDLDEPEVLDMPRKYGDHDLCSNIFVANAGNRAHLHFDGDHRQVLLHQMFGRKQVLLFQPEACVDLRTTSGAPWSSGVYLEQMSTQEQLDFVAEVGGYHAVLEPGETIYMPALIWHYLGYVDDAMSFNLRFRRNRFGRFLCVDNFHRDSYIQNLGSHLAASGAQDALTAAMPQIEAEYARPAASLRDKVTGMRTVLRQALERTLPETEPARFCPPQLDAQEVDKIIADIGQTARYVEPALAAKSRPTGPISPVQKQTIQNTAARLGYSDEALAHLLWNRLGKSELDRLSKTEAVQFMVYMRSPGSSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHU8</accession>
    <name>A0A0S2DHU8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">CalU5</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Radical SAM protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FE772_14335</name>
        <name evidence="6" type="ORF">GLE_2871</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947875.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2871"/>
    <dbReference type="EnsemblBacteria" id="ALN58219">
        <property type="protein sequence ID" value="ALN58219"/>
        <property type="gene ID" value="GLE_2871"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2871"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2833"/>
    <dbReference type="OMA" id="CHIGYVH"/>
    <dbReference type="OrthoDB" id="1311927at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW26657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="283" mass="31994" checksum="CAF10DE5A1769572" modified="2016-02-17" version="1">MHLSLLYRGRLSSCNYDCGYCPFAKTYDSREALRRDAADLARFVDWAGAQRMQLSVLFTPWGEGLVRRHYRQALVALSRMAHVRRAAIQTNLCVGLRWLDEADLGKLALWCTYHPTQVGRAAFLARCRELDRRGVRHSVGMVGLLEDLDEIEAMRRELPATTPMWVNAFDPRPPDYYDVAQIARIEAIDPHFRYNLAPAPSLGAPCLTGESVVSVDGDGEVRRCHFVDQPLGNLYDGSFAAQLRQRACPNARCDCYIGYAHRPDLPFQRDYAGGVLERVPSFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHX5</accession>
    <name>A0A0S2DHX5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TrbC/VirB2 family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">VirB2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">virB2</name>
        <name evidence="3" type="ORF">BV903_06235</name>
        <name evidence="4" type="ORF">FE772_14070</name>
        <name evidence="2" type="ORF">GLE_2817</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000011">
        <property type="protein sequence ID" value="OPD64802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947836.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000011.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2817"/>
    <dbReference type="EnsemblBacteria" id="ALN58165">
        <property type="protein sequence ID" value="ALN58165"/>
        <property type="gene ID" value="GLE_2817"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64802">
        <property type="protein sequence ID" value="OPD64802"/>
        <property type="gene ID" value="BV903_06235"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2817"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2774"/>
    <dbReference type="OMA" id="FAGYQIA"/>
    <dbReference type="OrthoDB" id="2049012at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007039">
        <property type="entry name" value="TrbC/VirB2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04956">
        <property type="entry name" value="TrbC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="122" mass="12919" checksum="D771597046506625" modified="2016-02-17" version="1">MNSNIYVKNFLSAFLMATAFVALLMLPEVSFAQTDAKARVSNFMNNLNSLLNIASVAIVTIAVIFAGYGIAFAHKRLSDVAPVLIGGFLIGAAAQLAKMVIPEDVGSDTTTSMVMAVLQNYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHZ8</accession>
    <name>A0A0S2DHZ8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hydrolase, alpha/beta fold family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947747.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2700"/>
    <dbReference type="EnsemblBacteria" id="ALN58048">
        <property type="protein sequence ID" value="ALN58048"/>
        <property type="gene ID" value="GLE_2700"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2700"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2659"/>
    <dbReference type="OMA" id="IFFAHAN"/>
    <dbReference type="OrthoDB" id="1498437at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="5"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="289" mass="32083" checksum="9FF3FAE9EA626AC2" modified="2016-02-17" version="1">MSDLLLFSHANGFPAPVYRVMLEQLSARYRIERPERIGHDPRYPVTLDWPHLVEELAERAVAAAGDARRIFLVGHSLGGYLSLLAAHRLAGTALAARLAGVVMLDSPLIAGWRARLVQLGRRTGLDNLVMPTRATLQRRRHWPDRAAVRAHFLAKPTFARWDQRVLNDYVEHGTRAADDGARELAFEREIEYRIYRSLPTTSLSGLAPQVRVPVGFLAGTRSRELRNAGEAATRRLVGERWAWVEGSHLFPMERPQDTAAAIEAMLKRIAPAAAEADARAPAAVRATGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI40</accession>
    <name>A0A0S2DI40_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytosolic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2767</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947797.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2767"/>
    <dbReference type="EnsemblBacteria" id="ALN58115">
        <property type="protein sequence ID" value="ALN58115"/>
        <property type="gene ID" value="GLE_2767"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2767"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2724"/>
    <dbReference type="OMA" id="RYNGCPF"/>
    <dbReference type="OrthoDB" id="120956at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046690">
        <property type="term" value="P:response to tellurium ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06974">
        <property type="entry name" value="TerD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003325">
        <property type="entry name" value="TerD"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0778">Tellurium resistance</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="687" mass="76887" checksum="1E9F974F7E25270F" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI47</accession>
    <name>A0A0S2DI47_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DsbE family thiol:disulfide interchange protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Thiol:disulfide interchange protein dsbE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">dsbE</name>
        <name evidence="9" type="ORF">FE772_14145</name>
        <name evidence="8" type="ORF">GLE_2832</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thioredoxin family. DsbE subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2832"/>
    <dbReference type="EnsemblBacteria" id="ALN58180">
        <property type="protein sequence ID" value="ALN58180"/>
        <property type="gene ID" value="GLE_2832"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2832"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2790"/>
    <dbReference type="OMA" id="CKEEHPL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015036">
        <property type="term" value="F:disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03010">
        <property type="entry name" value="TlpA_like_DsbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004799">
        <property type="entry name" value="Periplasmic_diS_OxRdtase_DsbE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00385">
        <property type="entry name" value="dsbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="7">
        <location>
            <begin position="48"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW28757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="207" mass="22584" checksum="1C6C36B3EDC09FD6" modified="2016-02-17" version="1">MNTPDSRPGSTSGATRWLPLAVFAALAILLAAGVWLSRNPDREKLPSPLIGKPAPRFSLPVLHEAGRLISTEDLRGAPYLLNVWGSWCPACRDEHPVLTRFAETKRVRVVGFNWKDEHADALRWLEQYGNPYFVVAVDYEGKAAIDWGIYGAPETFLVDAQGVVRWKFVGPLTDAVIREQLIPELDRIASKAGAPAAGASLAAGTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIC1</accession>
    <name>A0A0S2DIC1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_03120</name>
        <name evidence="4" type="ORF">D9T17_17050</name>
        <name evidence="3" type="ORF">FE772_15035</name>
        <name evidence="1" type="ORF">GLE_3009</name>
    </gene>
    <organism evidence="1 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 5">C3</strain>
        </source>
    </reference>
    <reference evidence="2 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">OH11</strain>
        </source>
    </reference>
    <reference evidence="3 8" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000005">
        <property type="protein sequence ID" value="OPD65521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000041">
        <property type="protein sequence ID" value="ROU05881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947976.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58357">
        <property type="protein sequence ID" value="ALN58357"/>
        <property type="gene ID" value="GLE_3009"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65521">
        <property type="protein sequence ID" value="OPD65521"/>
        <property type="gene ID" value="BV903_03120"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3009"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2970"/>
    <dbReference type="OMA" id="WANWERI"/>
    <dbReference type="OrthoDB" id="1784317at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD65521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROU05881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="115" mass="12938" checksum="B655544362F888C4" modified="2016-02-17" version="1">MTTTLQGRPTPTTPGLSYWASHYREAEFYREGLHFSDYAPAFYVGISVQLEHPGRDFDDPGLDLRGRYQRIRLGSALSWEQAQGAARASWERARDNAAAARQRIAQHMAELAAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIG7</accession>
    <name>A0A0S2DIG7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA-binding response regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">Response regulator transcription factor</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Two component transcriptional regulator, winged helix family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">BV903_22130</name>
        <name evidence="9" type="ORF">FE772_15410</name>
        <name evidence="7" type="ORF">GLE_3091</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000073">
        <property type="protein sequence ID" value="OPD61747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948034.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000073.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58438">
        <property type="protein sequence ID" value="ALN58438"/>
        <property type="gene ID" value="GLE_3091"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61747">
        <property type="protein sequence ID" value="OPD61747"/>
        <property type="gene ID" value="BV903_22130"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3091"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3050"/>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="23"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="6">
        <location>
            <begin position="146"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="146"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD61747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW26822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="255" mass="27577" checksum="1F352EBF77D4B7E4" modified="2016-02-17" version="1">MAAISAVHPGSGLNGADHRNSRRVAVVERDPNLRQQIQHSLLTRQFAVVECANATALYRNLLSAPCDIAVIASDLPDDNPRNVALHLRQHSDIGIIVLDAEAGYGGPSDGYHEIADACFRKPVDLDGLATVVTAMHSLQHHMRALPARAGSGQAEWELALDGWTLRTPDGASIDLSAPERSVLLRLVNTGAGGHPVSHDSLIGSLTNDVYDFDPHRLEMLIYRLRKKVAVMSPLPLPLRAVRGMGYLCTIVRASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIL9</accession>
    <name>A0A0S2DIL9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLE_3144</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3144"/>
    <dbReference type="EnsemblBacteria" id="ALN58491">
        <property type="protein sequence ID" value="ALN58491"/>
        <property type="gene ID" value="GLE_3144"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3144"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3102"/>
    <dbReference type="OMA" id="ANDETWD"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="89"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="65"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN58491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="989" mass="107976" checksum="3C98C336F2B75994" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIV0</accession>
    <name>A0A0S2DIV0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_14195</name>
        <name evidence="1" type="ORF">GLE_2843</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947854.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58191">
        <property type="protein sequence ID" value="ALN58191"/>
        <property type="gene ID" value="GLE_2843"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2843"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2802"/>
    <dbReference type="OrthoDB" id="2011140at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="183" mass="20657" checksum="536279DF359C9F33" modified="2016-02-17" version="1">MILKKFEIPAGRPIPEDQRGYFGPSAELVRFKPAPVLPAEVVGRRIDEVCSNLGTYGMGGAGMFGLRLDAQWLVFALWSAAQWMIAEGRRVEDARYARDGAPPPWRSDLGDELSGRVLGRTIAALDVRRRSMDLSLDDGFAIRIDEDPATRPIWEGNQKPRKFGWRDDLRRAVFLCPTDEIWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJB3</accession>
    <name>A0A0S2DJB3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HSAF FAD dependent oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">NAD(P)/FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_15975</name>
        <name evidence="5" type="ORF">GLE_3216</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
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        <property type="project" value="InterPro"/>
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            <end position="526"/>
        </location>
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            <end position="26"/>
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            <end position="569"/>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW26910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="584" mass="64493" checksum="6A4935012932DE3F" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJE8</accession>
    <name>A0A0S2DJE8_LYSEN</name>
    <protein>
        <submittedName>
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        </submittedName>
        <submittedName>
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        </submittedName>
    </protein>
    <gene>
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        <name evidence="4" type="ORF">GLE_3413</name>
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        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN58759">
        <property type="protein sequence ID" value="ALN58759"/>
        <property type="gene ID" value="GLE_3413"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="1201303at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
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        <location>
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            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW27057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="663" mass="72217" checksum="D0DF8E1E1342226B" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJF7</accession>
    <name>A0A0S2DJF7_LYSEN</name>
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        <recommendedName>
            <fullName evidence="10">Fumarate hydratase class I</fullName>
            <ecNumber evidence="10">4.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">GLE_3068</name>
    </gene>
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        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the reversible hydration of fumarate to (S)-malate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>(S)-malate = fumarate + H2O</text>
            <dbReference type="Rhea" id="RHEA:12460"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="EC" id="4.2.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the class-I fumarase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.2" evidence="10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3068"/>
    <dbReference type="EnsemblBacteria" id="ALN58415">
        <property type="protein sequence ID" value="ALN58415"/>
        <property type="gene ID" value="GLE_3068"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3068"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3028"/>
    <dbReference type="OMA" id="AGVLPMC"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004333">
        <property type="term" value="F:fumarate hydratase activity"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006091">
        <property type="term" value="P:generation of precursor metabolites and energy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Fe-S_hydro-lyase_TtdA-typ_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004647">
        <property type="entry name" value="Fe-S_hydro-lyase_TtdB-typ_cat"/>
    </dbReference>
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        <property type="entry name" value="Fe-S_hydroAse_TtdB_cat_sf"/>
    </dbReference>
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        <property type="entry name" value="Fe_dep_fumarate_hydratase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05681">
        <property type="entry name" value="Fumerase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Fumerase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF117457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00722">
        <property type="entry name" value="ttdA_fumA_fumB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00723">
        <property type="entry name" value="ttdB_fumA_fumB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 10 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumerase" evidence="11">
        <location>
            <begin position="10"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Fumerase_C" evidence="12">
        <location>
            <begin position="288"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN58415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="504" mass="54078" checksum="8051EF76E596ACD8" modified="2016-02-17" version="1">MVVRQDDLIQSVADALQYISYYHPVDYIKNLAAAYEREESVAAKDAIAQILINSRMCAEGHRPICQDTGIVTVFLEIGMDVRWDGATMGVEDMVNEGVRRAYNHPDNKLRASVLADPAGKRANTKDNTPAVVNVKVVPGNTVDVIVAAKGGGSEAKSKFAMLNPSDSIVDWVLKTVPTMGAGWCPPGMLGIGIGGTAEKAMLLAKESLMEPIDITELQARGASNRAEELRLELYEKVNALGIGAQGLGGLTTVLDIKVKDYPTHAANLPVAMIPNCAATRHAHFTLDGSGPVMLDPPSLEDWPKLTYDSSKGRRVDLDTVTAEDVASWKPGEVLLLNGKLLTGRDAAHKRIIDMLNKGEPLPVDFKGRFIYYVGPVDPVRDEVVGPAGPTTATRMDKFTEQVLAQTGLLGMVGKAERGPAAIEAIQKHKSVYLMAVGGAAYLVSKAIKASRVVGFADLGMEAIYEFTVQDMPVTVAVDSAGESVHKTGPKEWQARIGKIPVVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJK8</accession>
    <name>A0A0S2DJK8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA 2',3'-cyclic phosphodiesterase</fullName>
            <shortName evidence="2">RNA 2',3'-CPDase</shortName>
            <ecNumber evidence="2">3.1.4.58</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ligT</name>
        <name evidence="4" type="ORF">GLE_3116</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + H2O = a 3'-end 2'-phospho-ribonucleotide-RNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11828"/>
            <dbReference type="Rhea" id="RHEA-COMP:10464"/>
            <dbReference type="Rhea" id="RHEA-COMP:17353"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:83064"/>
            <dbReference type="ChEBI" id="CHEBI:173113"/>
            <dbReference type="EC" id="3.1.4.58"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 2H phosphoesterase superfamily. ThpR family.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.58" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948055.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3116"/>
    <dbReference type="EnsemblBacteria" id="ALN58463">
        <property type="protein sequence ID" value="ALN58463"/>
        <property type="gene ID" value="GLE_3116"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3116"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3073"/>
    <dbReference type="OMA" id="EPITWTV"/>
    <dbReference type="OrthoDB" id="1696971at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004113">
        <property type="term" value="F:2',3'-cyclic-nucleotide 3'-phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008664">
        <property type="term" value="F:2'-5'-RNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01940">
        <property type="entry name" value="RNA_CPDase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014051">
        <property type="entry name" value="Phosphoesterase_HXTX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004175">
        <property type="entry name" value="RNA_CPDase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35561">
        <property type="entry name" value="PTHR35561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02834">
        <property type="entry name" value="LigT_PEase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="SSF55144"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02258">
        <property type="entry name" value="2_5_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LigT_PEase" evidence="3">
        <location>
            <begin position="26"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="HXTX 1" evidence="2">
        <location>
            <begin position="59"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="HXTX 2" evidence="2">
        <location>
            <begin position="147"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="197" mass="21580" checksum="1002F319A30C8710" modified="2016-02-17" version="1">MHQSSLFGDPAPRQPAELHRLFFALWPDAGVRARIRERALALEAAQRPGGRLIGAHRYHLTLQFLGDFAELPQALAQRAGVAAAAVRADAFDFALDRAGSFANRDIPWWLGSAEPNPSLAALWDRLGVALAKQGVKVVASHRAHAPHVTVVREAAHGMSAPLAIDPVMWRIDRFVLLHSVLGKRNEYSLLGEWPLDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJM0</accession>
    <name>A0A0S2DJM0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948298.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58790">
        <property type="protein sequence ID" value="ALN58790"/>
        <property type="gene ID" value="GLE_3445"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3445"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3393"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595715" evidence="1">
        <location>
            <begin position="32"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="75" mass="8068" checksum="1CA60626C40019D5" modified="2016-02-17" version="1">MTLRPVLPLRRASVALAVAAFACGYAAVSTAAAPCPCFAEQRQCLADAASAPERRMCKLEFDRCMQRACPTPRAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJM8</accession>
    <name>A0A0S2DJM8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Allophanate hydrolase, subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_3141</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3141"/>
    <dbReference type="EnsemblBacteria" id="ALN58488">
        <property type="protein sequence ID" value="ALN58488"/>
        <property type="gene ID" value="GLE_3141"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3141"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3099"/>
    <dbReference type="OMA" id="QDLGRSH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003778">
        <property type="entry name" value="CT_A_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02626">
        <property type="entry name" value="CT_A_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00797">
        <property type="entry name" value="AHS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00724">
        <property type="entry name" value="urea_amlyse_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AHS2" evidence="5">
        <location>
            <begin position="54"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="351" mass="36908" checksum="93490B91DDAAABE3" modified="2016-02-17" version="1">MRIQRPRTVRPGGRRRPGERAAMTAALPDEEWIEVIAPGALSCVQDLGRAGWRHLGVGQGGALDPRCARLANALVGNPAEAAVLELTLHGPTLRLRAPTRLALLGAPCELRFDGRPLPAARPLELPAGTVSIGGMRAGVRAWLAVAGGFAVEAALGSSATDLRGGFGGLHGRALRAGDRLPLGPVRPPRRVDAPRVPGWWIDPDAGLDPHAPIRYVATAAPALVAAAQRFGDSGWRVDPASNRQGLRLGGEALDTPAAAGAGVSEPVAPGTIQLPADGQPIVLLADAQTVGGYPRLGRIIAADLPRLAQARPNAKLYFRACDEDEAREARRRMDADTARLRWAIADRLSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJY6</accession>
    <name>A0A0S2DJY6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase (GNAT) family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">GNAT family N-acetyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_24215</name>
        <name evidence="4" type="ORF">FE772_17755</name>
        <name evidence="2" type="ORF">GLE_3605</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000092">
        <property type="protein sequence ID" value="OPD61311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948412.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000092.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58949">
        <property type="protein sequence ID" value="ALN58949"/>
        <property type="gene ID" value="GLE_3605"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61311">
        <property type="protein sequence ID" value="OPD61311"/>
        <property type="gene ID" value="BV903_24215"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3605"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3548"/>
    <dbReference type="OMA" id="VCNCGYM"/>
    <dbReference type="OrthoDB" id="1809950at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="164" mass="18317" checksum="F8483A6CCE8EF4D0" modified="2016-02-17" version="1">MDRDFDIREIGPEHFHLAWPIFREVLARGESYNYAADLNLDGARAMWTSAPYRMFLAQSGDDVLGCYKLGPNQRGRGDHVANASYMVAESAWGQGVGTALCEHSLMQARKAGYLAMQFNYVVSTNAAAVHLWLKHGFAVVGQVPEAFRHPTLGLVDVYVMHRML</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJZ5</accession>
    <name>A0A0S2DJZ5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA-binding protein HU</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">DNA-binding protein HU-beta</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">HU family DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hupB</name>
        <name evidence="7" type="ORF">BV903_17925</name>
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    <organism evidence="5 11">
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        </lineage>
    </organism>
    <reference evidence="5 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 11">C3</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="journal article" date="2016" name="DNA Res." volume="0" first="0" last="0">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer, Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">M497-1</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="3">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">ATCC 29487</strain>
        </source>
    </reference>
    <reference evidence="6 14" key="4">
        <citation type="journal article" date="2017" name="DNA Res." volume="24" first="169" last="177">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
            <dbReference type="PubMed" id="28065880"/>
            <dbReference type="DOI" id=".1093/dnares/dsw055"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 14">M497-1</strain>
        </source>
    </reference>
    <reference evidence="7 13" key="5">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 13">B25</strain>
        </source>
    </reference>
    <reference evidence="9 15" key="6">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 15">OH11</strain>
        </source>
    </reference>
    <reference evidence="8 16" key="7">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 16">YC36</strain>
        </source>
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        <text evidence="1 3">Belongs to the bacterial histone-like protein family.</text>
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        <property type="entry name" value="DNABINDINGHU"/>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
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    </evidence>
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        </source>
    </evidence>
    <sequence length="90" mass="9397" checksum="36D19BCCC97CFC10" modified="2016-02-17" version="1">MNKAELVGAVAETAELSKTDATAAVDALIDVVTKALKKGDTVTLVGFGTFQVRKRAARQGRNPKTGETIKIPASKNPSFKAGKALKDAVN</sequence>
</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <source>
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
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        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_MTAY01000062.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3309"/>
    <dbReference type="EnsemblBacteria" id="ALN58655">
        <property type="protein sequence ID" value="ALN58655"/>
        <property type="gene ID" value="GLE_3309"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62052">
        <property type="protein sequence ID" value="OPD62052"/>
        <property type="gene ID" value="BV903_20425"/>
    </dbReference>
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    <dbReference type="PATRIC" id="fig|69.6.peg.3259"/>
    <dbReference type="OMA" id="AMEMIMT"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
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        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
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        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
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    </dbReference>
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    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD62052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="260" mass="27133" checksum="578D139FC656C180" modified="2016-02-17" version="1">MTESPLLIADRGAVRQITVNRPDKLNALNAATLDALLAAFEAAAADPAVRAVVLTGAGPKAFVAGADIAEMNGLAPVQGRDFSLRGQKLMRRIEKMPKPVIAMINGFALGGGLELAMGCHLRIAADSAKVGQPEINLGLIPGFGGTQRLLRLAGRAATLELCLLGAPIDAARAQQLGIVNRVVAAAELEAETFKLAEQLASSAPLALRGVLDCIAVGGECGIEEGLEYETAQFGLMFSTDDMREGTGAFLERRKPAFRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK47</accession>
    <name>A0A0S2DK47_LYSEN</name>
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        <submittedName>
            <fullName evidence="11">Acyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
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        <name evidence="13" type="ORF">FE772_17485</name>
        <name evidence="11" type="ORF">GLE_3552</name>
    </gene>
    <organism evidence="11 14">
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        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Xanthomonadaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="11 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">C3</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">B25</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
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        <property type="protein sequence ID" value="ALN58896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD64319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW27160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_MTAY01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3552"/>
    <dbReference type="EnsemblBacteria" id="ALN58896">
        <property type="protein sequence ID" value="ALN58896"/>
        <property type="gene ID" value="GLE_3552"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64319">
        <property type="protein sequence ID" value="OPD64319"/>
        <property type="gene ID" value="BV903_09055"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3552"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3496"/>
    <dbReference type="OMA" id="MWAKMAK"/>
    <dbReference type="OrthoDB" id="357522at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Acyl-CoA_dh-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020953">
        <property type="entry name" value="Acyl-CoA_DH_N_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
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        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
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        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF00441">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Acyl-CoA_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12418">
        <property type="entry name" value="AcylCoA_DH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AcylCoA_DH_N" evidence="9">
        <location>
            <begin position="3"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="81"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="164"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="283"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_C" evidence="10">
        <location>
            <begin position="469"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN58896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="OPD64319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW27160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="596" mass="63919" checksum="A10D1DD1B42BD16B" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK51</accession>
    <name>A0A0S2DK51_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_08870</name>
        <name evidence="4" type="ORF">FE772_17410</name>
        <name evidence="2" type="ORF">GLE_3538</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000019">
        <property type="protein sequence ID" value="OPD64286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948365.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58882">
        <property type="protein sequence ID" value="ALN58882"/>
        <property type="gene ID" value="GLE_3538"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64286">
        <property type="protein sequence ID" value="OPD64286"/>
        <property type="gene ID" value="BV903_08870"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3538"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3482"/>
    <dbReference type="OrthoDB" id="2098483at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046256">
        <property type="entry name" value="DUF6289"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19806">
        <property type="entry name" value="DUF6289"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594873" evidence="1">
        <location>
            <begin position="27"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="81" mass="8895" checksum="F76E21A2FF720831" modified="2016-02-17" version="1">MHKSSKSKLALIAFAAGMTLSLAASALPYPNPGESYIQTYYSDATYTEVVGERGYGDCLNPRWGVSTRYVRLVRVVCPVMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKR6</accession>
    <name>A0A0S2DKR6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Arsenate reductase</fullName>
            <ecNumber evidence="3">1.20.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">arsC</name>
        <name evidence="5" type="ORF">FE772_18185</name>
        <name evidence="4" type="ORF">GLE_3689</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[glutaredoxin]-dithiol + arsenate + glutathione + H(+) = arsenite + glutathionyl-S-S-[glutaredoxin] + H2O</text>
            <dbReference type="Rhea" id="RHEA:22016"/>
            <dbReference type="Rhea" id="RHEA-COMP:10729"/>
            <dbReference type="Rhea" id="RHEA-COMP:17668"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29242"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:48597"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:146199"/>
            <dbReference type="EC" id="1.20.4.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the ArsC family.</text>
    </comment>
    <dbReference type="EC" id="1.20.4.1" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948476.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3689"/>
    <dbReference type="EnsemblBacteria" id="ALN59033">
        <property type="protein sequence ID" value="ALN59033"/>
        <property type="gene ID" value="GLE_3689"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3689"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3633"/>
    <dbReference type="OMA" id="YLKHPPD"/>
    <dbReference type="OrthoDB" id="1650947at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008794">
        <property type="term" value="F:arsenate reductase (glutaredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03034">
        <property type="entry name" value="ArsC_ArsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006659">
        <property type="entry name" value="Arsenate_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006660">
        <property type="entry name" value="Arsenate_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30041">
        <property type="entry name" value="PTHR30041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03960">
        <property type="entry name" value="ArsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00014">
        <property type="entry name" value="arsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51353">
        <property type="entry name" value="ARSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW27277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="143" mass="15737" checksum="3BB93FCB1F017D0C" modified="2016-02-17" version="1">MRAVIYHNPDCGTSRNTLALIRHAGIEPQVIEYLRHPPERGRLLELIAGAGLSVREAIRTKDTPYFELGLDDPDATDAALIDAMLAHPILINRPFVQTDLGIRLCRPSEAVLALLPPIAAPFAKEDGEIVIDGHGRRPPRKEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKW0</accession>
    <name>A0A0S2DKW0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase/bleomycin resistance protein/dioxygenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">VOC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_18405</name>
        <name evidence="2" type="ORF">GLE_3737</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948512.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3737"/>
    <dbReference type="EnsemblBacteria" id="ALN59081">
        <property type="protein sequence ID" value="ALN59081"/>
        <property type="gene ID" value="GLE_3737"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3737"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3682"/>
    <dbReference type="OMA" id="LWPEYHP"/>
    <dbReference type="OrthoDB" id="1857145at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="127" mass="13254" checksum="3C0E91AA8AC8FBB1" modified="2016-02-17" version="1">MFHHLSLGVRDLARAGAFYDAVLGALGYRRVFDGDESIGYGLVDNQDLLLLNLTPAAAAPGDGTHLAFAAASRAEVDAFHRGGLSGGGRDNGAPGLRPDYGAHYYACFLIDPDGHRVEAVINAPASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL43</accession>
    <name>A0A0S2DL43_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Signal transduction histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3948</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3948"/>
    <dbReference type="EnsemblBacteria" id="ALN59290">
        <property type="protein sequence ID" value="ALN59290"/>
        <property type="gene ID" value="GLE_3948"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3948"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3885"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="107"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="250" mass="26200" checksum="E4B0751424674874" modified="2016-02-17" version="1">MRAHVSNRSGNRDASGPNNIGPEGPPASPSMSMDALAAASTDAADPFALVPLLALSGDGEAALPADRAAFVDWAALARRLAGAQGKAVRVEAVLDPFPRLPPERAAMLRDVGMELVANAVLHGIEPMSARRRLGKDPVGAVRLTLGFDEREGWLFCVRDDGRGVDLARLREALVSGGACTPAEAARLSERETIVKVFEPGVTTAMQAEGARGHGLGLPNAVERLRGLQARVSLVTVPGRSTEVRIAWPPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLD0</accession>
    <name>A0A0S2DLD0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UPF0060 membrane protein GLE_3942</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_3942</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the UPF0060 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3942"/>
    <dbReference type="EnsemblBacteria" id="ALN59284">
        <property type="protein sequence ID" value="ALN59284"/>
        <property type="gene ID" value="GLE_3942"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3942"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3879"/>
    <dbReference type="OMA" id="WLWAVEG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00010">
        <property type="entry name" value="UPF0060"/>
        <property type="match status" value="1"/>
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    <keyword evidence="1 5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
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            <begin position="20"/>
            <end position="40"/>
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            <begin position="101"/>
            <end position="119"/>
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    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="123" mass="13212" checksum="2A2B2D81703F5143" modified="2016-02-17" version="1">MGGPSGPTLSFPVAAMLKTLLLFLLTAVAEIVGCYLPYLWLRKGGSIWLLLPAAASLALFAWLLNLHPTASGRVYAAYGGVYVTVAIFWLWWVDAVKPSRWDLLGAGLCLAGMAVIMFAPRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLU1</accession>
    <name>A0A0S2DLU1_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_20110</name>
        <name evidence="2" type="ORF">GLE_4100</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW27599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4100"/>
    <dbReference type="EnsemblBacteria" id="ALN59442">
        <property type="protein sequence ID" value="ALN59442"/>
        <property type="gene ID" value="GLE_4100"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4100"/>
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    <dbReference type="OMA" id="VPHMFIV"/>
    <dbReference type="OrthoDB" id="349314at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
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        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
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        <location>
            <begin position="50"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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    <feature type="transmembrane region" description="Helical" evidence="1">
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            <end position="353"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="504"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="535" mass="56098" checksum="A62D970D92CF3575" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLX3</accession>
    <name>A0A0S2DLX3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidoglycan-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 12" type="primary">pal</name>
        <name evidence="13" type="ORF">BV903_01140</name>
        <name evidence="14" type="ORF">FE772_19890</name>
        <name evidence="12" type="ORF">GLE_4051</name>
    </gene>
    <organism evidence="12 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">C3</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">B25</strain>
        </source>
    </reference>
    <reference evidence="14 17" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the Pal lipoprotein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD65885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948743.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4051"/>
    <dbReference type="EnsemblBacteria" id="ALN59393">
        <property type="protein sequence ID" value="ALN59393"/>
        <property type="gene ID" value="GLE_4051"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65885">
        <property type="protein sequence ID" value="OPD65885"/>
        <property type="gene ID" value="BV903_01140"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4051"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3994"/>
    <dbReference type="OMA" id="ESNESCW"/>
    <dbReference type="OrthoDB" id="1544679at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02204">
        <property type="entry name" value="Pal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039001">
        <property type="entry name" value="Pal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014169">
        <property type="entry name" value="Pal_lipo_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02802">
        <property type="entry name" value="Pal_lipo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="5 12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0564">Palmitate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594949" description="Peptidoglycan-associated protein" evidence="10">
        <location>
            <begin position="20"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="11">
        <location>
            <begin position="58"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="25"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN59393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OPD65885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW27565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="174" mass="18579" checksum="A8959145F3D5180A" modified="2016-02-17" version="1">MNNAARILLAAVLCTAAVACSKKVKETAPTDTGPGSTTTQPGDSTGPVASGAYGPNDLDTDACLRQRVVYFDLDQDSLKPEFQAIVGCHAKYLRDRPSSRMTLEGNADERGSREYNLGLGERRGNAVSSAIQANGASGSQITVVSYGEERPVCTDSNEDCWAKNRRVEIVYTAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM49</accession>
    <name>A0A0S2DM49_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ATP-grasp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_20710</name>
        <name evidence="3" type="ORF">GLE_4229</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <sequence length="303" mass="33053" checksum="CEF212A93B6B28F8" modified="2016-02-17" version="1">MSRLALVTAIASAGQDDDLSPLLAACLARGLRAEIRAWDDPSVAWARYDAVLLRSPWDYSARYGEFLAWCERVDAASRLLNPWPVLRWNSDKRYLADLAARGVPVVPTAFVGADGDPLPALQEFLAAHADAEEFVVKPTVSAGSRDTQRYARAQEFAAANHLARLLDEGRDAMLQPYLAAVDRDGETALIHFNGGFSHAIRKGAMLQREDALNLRAVERIAAREAGEDERTVALHALNAASARLDLEEPLAYARVDLIRDAQGRPQVLELELCEPSLFFAHAPGSAERFAQVLDELLATSGAG</sequence>
</entry>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <sequence length="37" mass="4232" checksum="AE9A1A8421494EDE" modified="2016-02-17" version="1">MSDRVGRRGLLWQGFLWEGLAFRPDAFRSVAVKPQAI</sequence>
</entry>
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            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="gene ID" value="GLE_4405"/>
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</entry>
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    </evidence>
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        <source>
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    <sequence length="170" mass="18723" checksum="672A45C598F16DE8" modified="2016-02-17" version="1">MNDANAFPSQWRAMREADAALLACRFHLKKHADFARILAQALACASERNLALRFLRDDAGALSDAQLAELAPAIVDLAVDGNLDDLIVARQTLVRYAARFTSSRGVVEDAVARVMDGYLAREDDFVLRRLAELLLDAGFAHALQRLLAACKDHADPDIAEIHDDFSRHLA</sequence>
</entry>
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    <accession>A0A0S2DMT5</accession>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
    <sequence length="381" mass="40750" checksum="E9E98B432DD71B73" modified="2016-02-17" version="1">MKLKTLCLSCVAALALSAAAATTASAHDAPADDAGAAKANPFTATEVARFNEPWAMTFLPNGRLLVTEKRGVLKVLTIGGSAQTITGVPAVAYGGQGGFGDVILHPQFATNSLIYISYAERGTTSGTAGATVARAKLNLTSSGGSLSNLQVLWRQPKLSGSNHYGHRLAFGPDHKLWITSSERQKFDPAQDLNSPLGKVIRLNDDGSVPTDNPFYNRGGVAATVWSYGHRNLLGIAFDAQNKLWIHEMGPKGGDELNLIERGSNYGWPLVSQGDHYDGTPIPRHNTRPDLNAPEAWWNPVIAPAGFVIYSGTRFPNWAGSGLIGGLASQALVRVKFNGNTAAEAERYPMGKRIREVEQGPNGDVWLLEDGTNARLLRLTPL</sequence>
</entry>
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    <accession>A0A0S2DMW0</accession>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    <dbReference type="PATRIC" id="fig|69.6.peg.4212"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="213" mass="22643" checksum="0526020707963785" modified="2016-02-17" version="1">MRVEPGWSERARRRTRRREDRGTDRDRGGARPRRRPRPPMGPALSRARATPGAIREAVLATDSGPGSGCGEDDAAASRSGRTTAARRTRRPRSAVAGREGDGGVTREILGRRQRADGGATPPSPAQAGLRGFRRDRAGDHAATVTVAGPAGREGQANGARTEPNPAPPGGTKTWTRSLDPLTSQFTGCRRSATTALWKSPRREAIASSRKSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-06-17" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN17</accession>
    <name>A0A0S2DN17_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4682</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60023">
        <property type="protein sequence ID" value="ALN60023"/>
        <property type="gene ID" value="GLE_4682"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4682"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4618"/>
    <dbReference type="OrthoDB" id="1992437at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="101" mass="11046" checksum="DEA2E998487A2B07" modified="2016-02-17" version="1">MPPRNVDRFSSISAEEASGTDAASAAATAATAAVQALIPHRTRELAITYGLGARLHHGERHWDDIRDELARGWERLRGAERASWSQVEADVEGAWRLVLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNI0</accession>
    <name>A0A0S2DNI0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Metal dependent amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_23095</name>
        <name evidence="2" type="ORF">GLE_4751</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949287.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4751"/>
    <dbReference type="EnsemblBacteria" id="ALN60092">
        <property type="protein sequence ID" value="ALN60092"/>
        <property type="gene ID" value="GLE_4751"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4751"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4685"/>
    <dbReference type="OMA" id="TVNDFHQ"/>
    <dbReference type="OrthoDB" id="1456605at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242251" evidence="1">
        <location>
            <begin position="27"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="457" mass="48561" checksum="C4046058165B74FE" modified="2016-02-17" version="1">MSLRRAFHIVLSSLLTASAIVPAAHAATVAFVRVHVLPMDSERVLRDQTVIVEDGSIRAIGPNLRVPDDAQVIDGAGQAWLSPGLADMHTHSDSRQDMAVYLAHGVTTLLHMGEAPTAFAVKTRAAIERGELPGPRVYAAFMVDGSNRYGHLAVRGAAQARAVAELARANGFDFIKIYNDLDAPAFDALIAAGNDGGLKVIGHGLSAVGLERQIAVGQAAVAHAEEFFYSWLFRPGDDDGIAVPDPARIDAVVAALKRHGTYATADLATYAAVASQWGRAGATDAVLSQTQAGWLAPEERLEWRRRGDAYVARTGTLAPRLALLQRLVAAMAAADLPLMTGTDAPVVPGMFPGSALHAQLAALEAAGVSRYRALRAATRTPGDFIAQHRPGGDRFGRIAPGYRADLLLSATDPLDDLATLAQPLGVMAQGRWYPRARLRELTAQVADEYSNACARPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNM0</accession>
    <name>A0A0S2DNM0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_10390</name>
        <name evidence="2" type="ORF">GLE_4807</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000023">
        <property type="protein sequence ID" value="OPD63991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949328.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4807"/>
    <dbReference type="EnsemblBacteria" id="ALN60148">
        <property type="protein sequence ID" value="ALN60148"/>
        <property type="gene ID" value="GLE_4807"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63991">
        <property type="protein sequence ID" value="OPD63991"/>
        <property type="gene ID" value="BV903_10390"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4807"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4739"/>
    <dbReference type="OMA" id="FANINWL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013879">
        <property type="entry name" value="DUF1761"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08570">
        <property type="entry name" value="DUF1761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="134" mass="14336" checksum="D0489ED5D70E3BD3" modified="2016-02-17" version="1">MNVPLDQVNWLAIAAATASSFVLGGLWYGPLFKKTWCREAGVDPDAKPAHAGRVFATAIVCALLSATIFAALMPPQATAVDGFGVGFVVGLFFVSMSFGINYAFAGRSLKLWMIDSGYHIVQFVLYGVILGAWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNM8</accession>
    <name>A0A0S2DNM8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_23115</name>
        <name evidence="1" type="ORF">GLE_4755</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949290.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60096">
        <property type="protein sequence ID" value="ALN60096"/>
        <property type="gene ID" value="GLE_4755"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4755"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4689"/>
    <dbReference type="OrthoDB" id="2071545at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="82" mass="8797" checksum="ED4F9080B4F5F296" modified="2016-02-17" version="1">MATMRYHDGQDVRLGDVASFGAHDTCRVVVLIDEQAAVEGYIADEWAYLGGGCVLFAHDAGLVHYPADTLGDDADVSLIERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNQ0</accession>
    <name>A0A0S2DNQ0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD dependent epimerase/dehydratase family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">NmrA family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_06760</name>
        <name evidence="2" type="ORF">GLE_4921</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000012">
        <property type="protein sequence ID" value="OPD64728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949417.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000012.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4921"/>
    <dbReference type="EnsemblBacteria" id="ALN60262">
        <property type="protein sequence ID" value="ALN60262"/>
        <property type="gene ID" value="GLE_4921"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64728">
        <property type="protein sequence ID" value="OPD64728"/>
        <property type="gene ID" value="BV903_06760"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4921"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4850"/>
    <dbReference type="OMA" id="PYTIVHA"/>
    <dbReference type="OrthoDB" id="1928091at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="7"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="256" mass="26940" checksum="7E71209DA88D7A5F" modified="2016-02-17" version="1">MKFLVIGGTGLIGGKVVARLRAAGHEALAAAPSTGVDILTGAGLDAAMAGADTVIDLSNSPSFEDAAVLEFFATAGRTILAAEARAGVGHHLALSVVGTHKLAQSGYFRAKIEQERLIRESNRPYTIVHSTQFFEFLPGIVQSGADGERVRLPQAQIQPIAAEDVAAAVARLAQQPPANGIVEIAGPERLPMARLAQRYLRAVEDPREAVADPHARYFGAELDDGTLVPEGEAWLGALDFDAWLAQSGHARPAPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNV2</accession>
    <name>A0A0S2DNV2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide repeat family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_24495</name>
        <name evidence="2" type="ORF">GLE_5054</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949519.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60395">
        <property type="protein sequence ID" value="ALN60395"/>
        <property type="gene ID" value="GLE_5054"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5054"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4982"/>
    <dbReference type="OMA" id="NYYARIA"/>
    <dbReference type="OrthoDB" id="1383340at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="71"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="105"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="158" mass="17737" checksum="273BA7E52C5DECE7" modified="2016-02-17" version="1">MNPSEQCQRARALVGQGRTDEALQLYDRVLEAFPDHAPGYADRGTTHAMLGAHERALSDLERAMAMGLRDGWLLTTYASVLLALRRFDESLRYFDLAIELEPGHPFAYNNRATLHIERGDHAAAIADLERCLDFGPDEATRQMLERRLQGVRASLAKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP13</accession>
    <name>A0A0S2DP13_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase, families S8 and S53</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_4835</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949348.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60176">
        <property type="protein sequence ID" value="ALN60176"/>
        <property type="gene ID" value="GLE_4835"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4835"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4766"/>
    <dbReference type="OrthoDB" id="246371at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595486" evidence="4">
        <location>
            <begin position="31"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="5">
        <location>
            <begin position="600"/>
            <end position="717"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN60176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="811" mass="82663" checksum="57E484E77B7120FC" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP31</accession>
    <name>A0A0S2DP31_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter, ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">ATP-binding cassette domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_24635</name>
        <name evidence="5" type="ORF">GLE_5082</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949542.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5082"/>
    <dbReference type="EnsemblBacteria" id="ALN60423">
        <property type="protein sequence ID" value="ALN60423"/>
        <property type="gene ID" value="GLE_5082"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5082"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5009"/>
    <dbReference type="OMA" id="INWGRYG"/>
    <dbReference type="OrthoDB" id="1713578at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018632">
        <property type="entry name" value="AAA-associated_dom_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09821">
        <property type="entry name" value="AAA_assoc_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="11"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="48"/>
            <end position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW28361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="431" mass="47003" checksum="4167E4B8BA6E2C59" modified="2016-02-17" version="1">MTLHTCLRPLIDVRGLSQHYPKAGSEPLRVLDHVDLQLRAGEIVGLLGRSGSGKSTLLRAIAGLIRPSAGKVEFLGTPLSRAPADIAMVFQSFALFPWLTVLQNVELGLEARGVAPAQRRPRALAAIDLIGLDGYESAYPKELSGGMRQRVGLARALVVEPKVLLMDEPFSALDVLTAQTLRGDLLDLWAERRMPIEAILMVTHNIEEAVLMCDRILIFGSHPGRVVDEIQVPLAQPRDRFDPAFRGLVDAIYERMTGSAHPGSNARGGLAMELPPVSSNLIAGLIEAVAEPPYRGHADLPALAAQLQLEVDELFPIAESLQLLGLAELGDGDLRLSEAGARFAALDTDARKRLFARQLAAHVPLAAHIRRVLDERAAHQAPARRFRDELEDHMSPDYAAATVRAVTSWARYAEYFAYDEAADRFSLDNPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP55</accession>
    <name>A0A0S2DP55_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Agmatine deiminase</fullName>
            <ecNumber evidence="3">3.5.3.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4754</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.3.12" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4754"/>
    <dbReference type="EnsemblBacteria" id="ALN60095">
        <property type="protein sequence ID" value="ALN60095"/>
        <property type="gene ID" value="GLE_4754"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4754"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4688"/>
    <dbReference type="OMA" id="IDFRFCE"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047632">
        <property type="term" value="F:agmatine deiminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004668">
        <property type="term" value="F:protein-arginine deiminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009446">
        <property type="term" value="P:putrescine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007466">
        <property type="entry name" value="Peptidyl-Arg-deiminase_porph"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31377">
        <property type="entry name" value="PTHR31377"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04371">
        <property type="entry name" value="PAD_porph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595492" evidence="2">
        <location>
            <begin position="24"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="377" mass="41541" checksum="B4E2990BD20874D9" modified="2016-02-17" version="1">MPTPPLPAARPAWLALAAGALFAAALGQPGAARAQSGYMPDETARHDATWLQWPHANTYGRAYRDRLDPTWVAMTRALIASERVHIVVYDAGEQARVRKLLGAAGVALDRVSFLIRPTDDVWVRDNGPLFVYDRNDRLAIGDWGFNGWGLDAPYRKDDTVPAAVAQRLGLPRIDLNDVVLEGGAIEVDGRGTLLATRSSTREPQRNAELSEAELEQVLRDQLGVEKFIWLDGKDGGKEDITDMHVDGFARFGLPDTIVTMNRADLREWGLSGADIERLYAASDVDGKPYRFVQLPLTANDVVTEYGYALGYKGSYVNFYVGNTVVLMPEYKDPNDAKAKAILQRAFPGRTVIGIDVRNLYRNGGMVHCVTQQQPAAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP63</accession>
    <name>A0A0S2DP63_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, DoeR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_4828</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
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    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949344.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4828"/>
    <dbReference type="EnsemblBacteria" id="ALN60169">
        <property type="protein sequence ID" value="ALN60169"/>
        <property type="gene ID" value="GLE_4828"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4828"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4759"/>
    <dbReference type="OMA" id="REWPGSE"/>
    <dbReference type="OrthoDB" id="1654295at2"/>
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    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
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        <property type="entry name" value="HTH_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026881">
        <property type="entry name" value="WYL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08279">
        <property type="entry name" value="HTH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13280">
        <property type="entry name" value="WYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="3">
        <location>
            <begin position="4"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="318" mass="35101" checksum="6CBBB61117F38B3C" modified="2016-02-17" version="1">MLKTSTRLLRLLSLLQSRRHWTGAELCERLEVDARTVRRDVDRLRELGYPVQASAGVGGGYRLAAGASLPPLLLDDDEAVAMVVALRSAASSVARIEDTAVGLLGKLDQLLPARLRRRVGALYSVTLSLGQNQESPDVDTLTELAGACRDHRLLELDYNDRGGRASQRTIEPLRLVNSGRRWYLLAWDRSRDDWRLFRADRIRGLRCGGGFVPRKFPEDVAAYVQRSISQVMTGEGLRVRLRGSAEALAPTLPPWCGVLEHIDEGNSLLHVRGDSAEEILALLALTGVEFELIDGAERVAQLREVAQRLLRGLDAQAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPG6</accession>
    <name>A0A0S2DPG6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5278</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5278"/>
    <dbReference type="EnsemblBacteria" id="ALN60619">
        <property type="protein sequence ID" value="ALN60619"/>
        <property type="gene ID" value="GLE_5278"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5278"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5196"/>
    <dbReference type="OMA" id="FHWAALG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025737">
        <property type="entry name" value="Phenol_MetA_deg_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13557">
        <property type="entry name" value="Phenol_MetA_deg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595068" evidence="1">
        <location>
            <begin position="28"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="260" mass="27297" checksum="C457F4F60672E651" modified="2016-02-17" version="1">MDQALSPRRAALAWLATALVAPALAQAQTDTPAFDRPGIAFSTGTLPRGGFAWEQGLPDFERDRSGGVRSTGYSAATTLRLGLTDRLELQLSGSPYNYSRQRGGGQRDSARGAGDTALALKLALPSRHEKFSWGLLGSAAVATGDRDFSDGRDQYALGATVAYDFDDATSGSLYLNVERSGGADAWTFSPSLSRAFGARWGGYVEAGWTRTERAPDTGVAGAGVTFMATPTIQLDASLDAGLNDAAPDWQGGIGVSVFFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPM3</accession>
    <name>A0A0S2DPM3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ankyrin repeat domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Phospholipase accessory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">D9T17_03860</name>
        <name evidence="3" type="ORF">GLE_5167</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">OH11</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000012">
        <property type="protein sequence ID" value="ROU08433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949603.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000012.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5167"/>
    <dbReference type="EnsemblBacteria" id="ALN60508">
        <property type="protein sequence ID" value="ALN60508"/>
        <property type="gene ID" value="GLE_5167"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5167"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5089"/>
    <dbReference type="OMA" id="FFAMQNS"/>
    <dbReference type="OrthoDB" id="1360387at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242258" evidence="2">
        <location>
            <begin position="21"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="102"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="136"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="169"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROU08433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <sequence length="245" mass="25444" checksum="9B2E86C08167D182" modified="2016-02-17" version="1">MMRTAAIVASSLLLALAAAACRGNSMDDAKQAFPDARSAQLAQAVAEGDAAQVRALVAAGADPNARGDRDVNLLQYAMLKQSPKGLEALLDSGADPSRPGLGGATAMHGAAIANDPQYLQLLLAHRADPDVAHAETGQTPLSEAASPRYQAQFAALLKAGADPNRADRMGNTPLHQAAKLNATAQVLALLEAGADPRARNAQGASFQTFLFKLPADKLSEPARAERAKVTAWLQQHDVAVEDGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPT8</accession>
    <name>A0A0S2DPT8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nitrogen regulatory protein P-II</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">P-II family nitrogen regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">glnB</name>
        <name evidence="5" type="ORF">BV903_11235</name>
        <name evidence="7" type="ORF">D9T17_03975</name>
        <name evidence="6" type="ORF">FE772_24910</name>
        <name evidence="4" type="ORF">GLE_5139</name>
    </gene>
    <organism evidence="4 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 8">C3</strain>
        </source>
    </reference>
    <reference evidence="5 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">OH11</strain>
        </source>
    </reference>
    <reference evidence="6 11" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 11">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000026">
        <property type="protein sequence ID" value="OPD63871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000012">
        <property type="protein sequence ID" value="ROU08455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949583.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000012.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5139"/>
    <dbReference type="EnsemblBacteria" id="ALN60480">
        <property type="protein sequence ID" value="ALN60480"/>
        <property type="gene ID" value="GLE_5139"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63871">
        <property type="protein sequence ID" value="OPD63871"/>
        <property type="gene ID" value="BV903_11235"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5139"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5064"/>
    <dbReference type="OMA" id="HQIEVNF"/>
    <dbReference type="OrthoDB" id="2021322at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
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    </dbReference>
    <dbReference type="GO" id="GO:0030234">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002187">
        <property type="entry name" value="N-reg_PII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002332">
        <property type="entry name" value="N-reg_PII_urydylation_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30115">
        <property type="entry name" value="PTHR30115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00543">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039144">
        <property type="entry name" value="GlnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00340">
        <property type="entry name" value="PIIGLNB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00938">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51343">
        <property type="entry name" value="PII_GLNB_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00496">
        <property type="entry name" value="PII_GLNB_UMP"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1 3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="O-UMP-tyrosine" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR039144-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR602187-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD63871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW28408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROU08455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="112" mass="12188" checksum="C8BB31FCB8BA2C0B" modified="2016-02-17" version="1">MKLIIAIIRPFKLDEVREALTEVGVSGITVTEVKGFGRQKGHTELYRGAEYVVDFLPKLKIECAVPDGQLDAALEAIQNAARTGKVGDGKIIVLPVENTVRIRTGELDDDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ23</accession>
    <name>A0A0S2DQ23_LYSEN</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5367</name>
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    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60708">
        <property type="protein sequence ID" value="ALN60708"/>
        <property type="gene ID" value="GLE_5367"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5367"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5282"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="76" mass="8638" checksum="8DCC7592C7C83962" modified="2016-02-17" version="1">MHCRGRGSRRSYSRIRTLTTVIPAKAGTHFDFAAASAVIDVSRDDKPPSKAFVRKRPSYFLLSARQKKVAKEKRLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ75</accession>
    <name>A0A0S2DQ75_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Lipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_25110</name>
        <name evidence="3" type="ORF">GLE_5184</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949616.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5184"/>
    <dbReference type="EnsemblBacteria" id="ALN60525">
        <property type="protein sequence ID" value="ALN60525"/>
        <property type="gene ID" value="GLE_5184"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5184"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5104"/>
    <dbReference type="OMA" id="RAKEIAW"/>
    <dbReference type="OrthoDB" id="754125at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipase_3" evidence="2">
        <location>
            <begin position="100"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="402" mass="43759" checksum="A658814F322E5ECF" modified="2016-02-17" version="1">MSLNSQQYAALAQDSYNPRRQGEEVQLDGVRYNVLRHVDRPSGYQGTIYQRADTGEIVVAHRGTEFDRQPVRDGLADAGMVTSRANVQANDAIALTREAMQIARASGTSPEVTVTGHSLGGTLAQVSAHHFDLRGETFNAYGAVSLNRRIPEGGDRMVNHVMAGDPVSAASQHYGQVRVYANQQEIDTLRDKGYENNRSGWDLRNPLTAAGSLMGSHSMHNFTNVDGNGRPDRSVLTDPQAQQRAQDFDPMIDKYRGDVMAARRGLTGALRSPLGTVEDAIDGIRGPLPAGEPARREERERQRHSSLDAPETLPRLQPAMGLRASADDPSSVVDRMLAAAQSGDRDAFRQATQAAAANDPGRNLRQEAVATVDRQEQQALAQQAQKPQVEQPDAPSRGPRMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ98</accession>
    <name>A0A0S2DQ98_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_5447</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949816.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60788">
        <property type="protein sequence ID" value="ALN60788"/>
        <property type="gene ID" value="GLE_5447"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5447"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5363"/>
    <dbReference type="OrthoDB" id="2093117at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595418" evidence="2">
        <location>
            <begin position="21"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="322" mass="33015" checksum="26C24F9B364689C2" modified="2016-02-17" version="1">MRALSPLALGLLIATAPALAAAQQTNVSPAKSTSPQPVFSGSDFCDSCGTPPLYTEGAGAPGGGAAPAQALDPGEVSASSCEVSMVVSPQVPGSTAPGYARIRDLPYTAAIRAALQAADEWPLLPLLLQRIDLPTPGIGAARAPAAAAMIDLPAASEATFLEWSFAAAPDAVGESPGARVLALTVSVDPRGAFLRADWLATPNAQWSYYTGAGAPPPATPMPVASRVAKLYDAGRFSAQRLTLLHDGAWVHVGVGEPVREWLSFELPDAQWQPARLRNGLLRGTALGDGQGLQMQWPTLSHGVLNPAPSTPPPTQSAAGAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQU3</accession>
    <name>A0A0S2DQU3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_05505</name>
        <name evidence="4" type="ORF">D9T17_02515</name>
        <name evidence="3" type="ORF">FE772_00560</name>
        <name evidence="1" type="ORF">GLE_5468</name>
    </gene>
    <organism evidence="1 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 5">C3</strain>
        </source>
    </reference>
    <reference evidence="2 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">OH11</strain>
        </source>
    </reference>
    <reference evidence="3 8" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000010">
        <property type="protein sequence ID" value="OPD64949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000006">
        <property type="protein sequence ID" value="ROU08967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949831.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000006.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60809">
        <property type="protein sequence ID" value="ALN60809"/>
        <property type="gene ID" value="GLE_5468"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64949">
        <property type="protein sequence ID" value="OPD64949"/>
        <property type="gene ID" value="BV903_05505"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5468"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5383"/>
    <dbReference type="OrthoDB" id="2020052at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025161">
        <property type="entry name" value="Put_IS4/IS5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13340">
        <property type="entry name" value="DUF4096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD64949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROU08967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="135" mass="16087" checksum="84DE40D81E16589E" modified="2016-02-17" version="1">MQTEIRRDRIGHGREDARGRARFVQLSDSEWPLLEQVVRQVIALEDSRRPDTRRFVDAALSVMVGQCAWTQLPEDQFGDWRVCYNRNERWIERGVWTVLANSGVMLEAWSARVVAYAERRVREKRFRAKRQRRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQV1</accession>
    <name>A0A0S2DQV1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5526</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949866.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60867">
        <property type="protein sequence ID" value="ALN60867"/>
        <property type="gene ID" value="GLE_5526"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5526"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5442"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1590.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007338">
        <property type="entry name" value="DUF416"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023381">
        <property type="entry name" value="YP001051499.1-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04222">
        <property type="entry name" value="DUF416"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="192" mass="21874" checksum="B051B01F64697362" modified="2016-02-17" version="1">MNIEPLICRHLGSASEWKRLAFMASCCEPMLLNFRLYHEASRLGSPDLLRRGLDFAWQTARDDTVDGEADELVKPSRLQAPSRHDEGHSFAQAAIQTCFAISHTLRSLRGPRVLDALDVADASIYAIELHYRNELFLTKRTRSDREFLRRTEIMRLAKSLERLSAAPERDRLKAVARLRCSAQRAPSTLVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQW3</accession>
    <name>A0A0S2DQW3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cell wall surface anchor family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_5291</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949694.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5291"/>
    <dbReference type="EnsemblBacteria" id="ALN60632">
        <property type="protein sequence ID" value="ALN60632"/>
        <property type="gene ID" value="GLE_5291"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5291"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5209"/>
    <dbReference type="OMA" id="KMDATMS"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595468" evidence="2">
        <location>
            <begin position="22"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="270" mass="26579" checksum="34DF02EE43E6B94D" modified="2016-02-17" version="1">MKLMHSLLALALAALASPAFAEGDDARIHSDTSVSNRIQVGGRVAVKGQIRVASESAATVDQDQHTLSNGSLGDGDHDARLGDSALSNAQGNIGANVAAGVGNAQSNDTALSAVDGEKVFASAMVFGAQSALGNFATTNTDDTFYRATLDGNALSNAKGNIGVNVAAGVGNVQGNGMAASVNSSGTVALATSDSEQRSLANVLDSDGRRLSLDLYASLGGNALSGAQGNIGVNVASGVGNLQHNGLAIATASCGACAPPPPPPSCTSCGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-01-23" modified="2022-01-19" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A1EBU2</accession>
    <name>A1EBU2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Lipoprotein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">sctJ</name>
        <name evidence="13" type="ORF">FE772_24755</name>
        <name evidence="12" type="ORF">GLE_5108</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2006-11" db="EMBL/GenBank/DDBJ databases">
            <title>A type III secretion system from the microbial antagonist and biological control bacterium, Lysobacter enzymogenes strain C3.</title>
            <authorList>
                <person name="Reedy R.M."/>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">C3</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell outer membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the YscJ lipoprotein family.</text>
    </comment>
    <dbReference type="EMBL" id="EF119743">
        <property type="protein sequence ID" value="ABL59995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949560.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5108"/>
    <dbReference type="EnsemblBacteria" id="ALN60449">
        <property type="protein sequence ID" value="ALN60449"/>
        <property type="gene ID" value="GLE_5108"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5108"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5033"/>
    <dbReference type="OMA" id="QERAQMV"/>
    <dbReference type="OrthoDB" id="858412at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006182">
        <property type="entry name" value="FliF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003282">
        <property type="entry name" value="T3SS_HrcJ/YscJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043427">
        <property type="entry name" value="YscJ/FliF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30046">
        <property type="entry name" value="PTHR30046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01514">
        <property type="entry name" value="YscJ_FliF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01338">
        <property type="entry name" value="TYPE3OMKPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02544">
        <property type="entry name" value="III_secr_YscJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="8 9 12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 9" id="KW-0564">Palmitate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="YscJ_FliF" evidence="10">
        <location>
            <begin position="41"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ABL59995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN60449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW28383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="281" mass="30113" checksum="8054A8A266DC2469" modified="2007-01-23" version="1">MGRASGVNAAGFKAACFKAAGFKAGRILAALLACLLIVGCTRTPLYSQLDEQQANELMAALLDAGIPAEKDPSPSKTGWEVMVNRGDIPYAMQVLNSRGLPRAQYRSLGEVFKKEGFASSALEEKARYLYGLSQELSRTLTRIDGVVEARVHIALPDRDPLGGNVQDSSASVLIFERPGQSLRDRETDIKVFVKDSVEGLDDVNKVTVKFFTVQSPPKVHQAAGPLNAVIGSIDLSAVIIGAGVLVLLAIAAFFFGRLRSRFFPPSQPPPQSNARGGVWNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA60</accession>
    <name>A0A0S2DA60_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, XRE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55379">
        <property type="protein sequence ID" value="ALN55379"/>
        <property type="gene ID" value="GLE_0020"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0020"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.27"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="64"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="129" mass="14319" checksum="239F0AACC8EFBF25" modified="2016-02-17" version="1">MVAPLMKRITMYKKELAALKAPARATRSTASKNASATVTLPSRVNHPAQTSGEEAQAWYSTKNLIELREKFDLSAAGMADLVGVRPWSIYRWEAGEKPSVASMIKVASLRKISRTRALRMLEELRNSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA73</accession>
    <name>A0A0S2DA73_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Barstar family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_01300</name>
        <name evidence="3" type="ORF">GLE_0077</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the barstar family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945777.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0077"/>
    <dbReference type="EnsemblBacteria" id="ALN55436">
        <property type="protein sequence ID" value="ALN55436"/>
        <property type="gene ID" value="GLE_0077"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0077"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.82"/>
    <dbReference type="OMA" id="HFLYANC"/>
    <dbReference type="OrthoDB" id="2047621at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000468">
        <property type="entry name" value="Barstar"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035905">
        <property type="entry name" value="Barstar-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01337">
        <property type="entry name" value="Barstar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52038">
        <property type="entry name" value="SSF52038"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Barstar" evidence="2">
        <location>
            <begin position="42"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="145" mass="15671" checksum="3F706DF2C1E7048A" modified="2016-02-17" version="1">MSATDPRELLADPAQAGAYFIDARDSQALADAATELGFALARVDFAGCRDKDDALARIAAGLRFPEWFGGNWDALDDSVNDLSWWPAPGYLLLIERTGAWQAAHADDAATLVEILGDAAQDWAKTRVPFWALLPLPEAELAQMAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA94</accession>
    <name>A0A0S2DA94_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0097</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55456">
        <property type="protein sequence ID" value="ALN55456"/>
        <property type="gene ID" value="GLE_0097"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0097"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.101"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="210" mass="23128" checksum="82F6F207F23726E7" modified="2016-02-17" version="1">MHRAGAAQGGQAAMTAWFGEGARRGTRIARPRGAWLRVAALALCLAAAPVALADEAERYAPPGAVLSEPRAHPDWPCLASLLQQIVDDQGARGVNALHIGRVVREDDDGNDFVRVYWPRRRAILLVSLNRNGCADPDYRYDSLGLGWYRTKARIDLDHHVRATEAEISGSSFLVTRAWADAVIAECTTHGTELKLRRARRRRRDADADAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAE7</accession>
    <name>A0A0S2DAE7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamine amidotransferase class-I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0127</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0127"/>
    <dbReference type="EnsemblBacteria" id="ALN55486">
        <property type="protein sequence ID" value="ALN55486"/>
        <property type="gene ID" value="GLE_0127"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0127"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.130"/>
    <dbReference type="OMA" id="PWIQTLK"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01741">
        <property type="entry name" value="GATase1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044992">
        <property type="entry name" value="ChyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695">
        <property type="entry name" value="PTHR42695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="1">
        <location>
            <begin position="71"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="241" mass="26114" checksum="84BEEABDCA56CD8E" modified="2016-02-17" version="1">MKPPFLILETGQPVPSMRRHRGFPHWIRVAAGLGRDEAVVVNVEAGEDPPGREGFAGAIVTGSGAMVTDRAPWSERSAQWLREAAHAGLPLFGICYGHQLLAHALGGEVGNHPGGREMGTVHLELHPTAAADPLFAGLPARFPAQATHLQTVLRAPEGAAVLARSSHDACHAFRWGERAWGVQFHPEFSAGHMRGYVRARQDALRNEGLCPRTVAREISAAPHARRVLRRFVGHARALHGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAG1</accession>
    <name>A0A0S2DAG1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55389">
        <property type="protein sequence ID" value="ALN55389"/>
        <property type="gene ID" value="GLE_0030"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0030"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.37"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="123" mass="13980" checksum="7246FD7E64607423" modified="2016-02-17" version="1">MIRWYIRSRQYILPKDGAFVARPEQLGKSFKTQANIALGIVVAYFFVLWSGLAFVLYLPNWAQVILIAMMLVFPVIGPMFAWFSAKLATAHRLTAELDVYHPVRKKPARQSRSKAAKALPKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAH3</accession>
    <name>A0A0S2DAH3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transporter, solute:sodium symporter (SSS) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_0199</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0199"/>
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</entry>
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</entry>
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</entry>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">C3</strain>
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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    </feature>
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    </evidence>
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    </evidence>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="210" mass="23930" checksum="8198A0510A6C8CFE" modified="2016-02-17" version="1">MLIGGGIGAIAGASAGKGVAEKIDPTGEAGYWRDEYTRRPYYDPKYDYDRDYGPAYAYGATARSNLGDRSWDPSTEVELEREWAKARGDSRLEWSDARAAVQDSWGRADRTYSTYEATDRYHESRFDQAPYRDEGAQYGDYRPAYRLGTQARHQYADREWDDRLESELGERWNNVKGESRLGWDKAKSAAKDAWHSVERALPGDADKDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBD8</accession>
    <name>A0A0S2DBD8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Arginine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Arginyl-tRNA synthetase</fullName>
            <shortName evidence="9">ArgRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 13" type="primary">argS</name>
        <name evidence="14" type="ORF">FE772_02075</name>
        <name evidence="13" type="ORF">GLE_0249</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">C3</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg)</text>
            <dbReference type="Rhea" id="RHEA:20301"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.19"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.19" evidence="9"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945902.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0249"/>
    <dbReference type="EnsemblBacteria" id="ALN55608">
        <property type="protein sequence ID" value="ALN55608"/>
        <property type="gene ID" value="GLE_0249"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0249"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.251"/>
    <dbReference type="OMA" id="NKPLHLG"/>
    <dbReference type="OrthoDB" id="1146366at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00671">
        <property type="entry name" value="ArgRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00123">
        <property type="entry name" value="Arg_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001278">
        <property type="entry name" value="Arg-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005148">
        <property type="entry name" value="Arg-tRNA-synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036695">
        <property type="entry name" value="Arg-tRNA-synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035684">
        <property type="entry name" value="ArgRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956">
        <property type="entry name" value="PTHR11956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03485">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00750">
        <property type="entry name" value="tRNA-synt_1d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01038">
        <property type="entry name" value="TRNASYNTHARG"/>
    </dbReference>
    <dbReference type="SMART" id="SM01016">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55190">
        <property type="entry name" value="SSF55190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00456">
        <property type="entry name" value="argS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arg_tRNA_synt_N" evidence="12">
        <location>
            <begin position="3"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="DALR_1" evidence="11">
        <location>
            <begin position="441"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="9">
        <location>
            <begin position="129"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN55608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW24644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="562" mass="61770" checksum="9452C40EFBDCA561" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBE1</accession>
    <name>A0A0S2DBE1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0488</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55846">
        <property type="protein sequence ID" value="ALN55846"/>
        <property type="gene ID" value="GLE_0488"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0488"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="83" mass="8861" checksum="A972C32CEB4F06C9" modified="2016-02-17" version="1">MRGESAHGRCSSEAVAGDETGRCPRVLRNDPSRRLCARSKAHHKVRVGEVAKAGRARRRGRAVTDARVRGAASSRCGNADAHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBN9</accession>
    <name>A0A0S2DBN9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55948">
        <property type="protein sequence ID" value="ALN55948"/>
        <property type="gene ID" value="GLE_0590"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0590"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="42" mass="4828" checksum="A87381EA6171C63A" modified="2016-02-17" version="1">MARHPDRALRPAAMRTVPTPPRRIHDRTLAAADRRIPEETAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBR6</accession>
    <name>A0A0S2DBR6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_02910</name>
        <name evidence="2" type="ORF">GLE_0426</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946026.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55784">
        <property type="protein sequence ID" value="ALN55784"/>
        <property type="gene ID" value="GLE_0426"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0426"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.423"/>
    <dbReference type="OrthoDB" id="1757195at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242646" evidence="1">
        <location>
            <begin position="29"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="89" mass="9345" checksum="21D8BF10B401B7E7" modified="2016-02-17" version="1">MRKRNKSWTFAAAAAALAIAGVAAPALSQPGAYVEIRTYADSAGNVRGVQYISRGCTDPQPVGWGLWSGSFTTQRGTCFRIAPPGGELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBU8</accession>
    <name>A0A0S2DBU8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946088.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55869">
        <property type="protein sequence ID" value="ALN55869"/>
        <property type="gene ID" value="GLE_0511"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0511"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.506"/>
    <dbReference type="OrthoDB" id="1975779at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="259" mass="27905" checksum="30E9EBD034BB7610" modified="2016-02-17" version="1">MNRHDHELSAPLADAVRAAQAAPADAADAAQARLLERLRAQPRPADGARRPALPRWLAAGAVAALAVIAVLAVPLLPGGGDAFAAVQQRLREAAVLDLRVIQRIDGQVLQTSRTVVDRRGVLRTDVGAQLSVIVDPPRRRVLTLLHDSREARVAPLSAQAAAAAGDLGWLRELRDFQGRAERLPDQRDRDGRTVQRWSLRLGGTPAEMWADAAGLPLRLRRAGPSGLRIDYRFTLDPPLAPGWLSSEPPPGYALADAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBV6</accession>
    <name>A0A0S2DBV6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Universal stress protein family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0636</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946179.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55994">
        <property type="protein sequence ID" value="ALN55994"/>
        <property type="gene ID" value="GLE_0636"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0636"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.625"/>
    <dbReference type="OMA" id="ISHAWDI"/>
    <dbReference type="OrthoDB" id="2040681at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="218"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="278" mass="29804" checksum="310E929BF24BFF27" modified="2016-02-17" version="1">MYKDLMIPMTGSAGDADALRLAVKLAARHSARLSVLESVDLPVPISHAWDIVPDPTGGGVYDALRERGQQRLAELKARLDDETVCWDARAVEALYADAPHTVAREAFDADLCLLAGSGGRADGAAALHAWFTALLLESGRPVLVVPPASGPTLPLRRAMVAWQPTRPTARAVHDALPLLADAGLVELVVIGRDDDDPALDSARRMVAHLVRHSIPTDLVNLRAGEHSVAEVLLDYAERSGVQLLVAGGYGHSRLREWVLGGVTRELLLSAQLPVFFGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBW3</accession>
    <name>A0A0S2DBW3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0458</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55816">
        <property type="protein sequence ID" value="ALN55816"/>
        <property type="gene ID" value="GLE_0458"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0458"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="249" mass="26091" checksum="37AD407C1788AFE1" modified="2016-02-17" version="1">MLVVDQAGEQIPIRPGEPCALSLEVGIANRGQPLGRFIEIAAQEIPKLGQLVGVADHLGYRDLFADRAAAGVETTKSSPFQLPITKVPPRSCAKSTDTTRLFHSFAAASATAEYATLSISNAPTRVFAPCSWTKRTSAPDVVGQVATRTRPLPAASSSNVSSQPRSGSAAIWVVAGGAGAGTTVPGVGGHSDRGRLRALDVRALGALSQTQSNAADSAVMAKKPDLERTMAHWKFKPRQPRISPTDPFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBZ7</accession>
    <name>A0A0S2DBZ7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="9">C4-dicarboxylate transport transcriptional regulatory protein DctD</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="10">Sigma-54-dependent Fis family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dctD</name>
        <name evidence="10" type="ORF">FE772_04155</name>
        <name evidence="9" type="ORF">GLE_0694</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946223.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0694"/>
    <dbReference type="EnsemblBacteria" id="ALN56052">
        <property type="protein sequence ID" value="ALN56052"/>
        <property type="gene ID" value="GLE_0694"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0694"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.682"/>
    <dbReference type="OMA" id="YYRLHIV"/>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="3"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="7">
        <location>
            <begin position="154"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW24985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="454" mass="49010" checksum="C98569C73504E357" modified="2016-02-17" version="1">MRTVLVIDDNPAVGTALDLLFGLRDIRVLTAQSPQQGLDLLAREDIGLVLQDMNFTADTTSGQEGVALFRAIRARHPDLPIILLTAWTHLDIAVDLAKAGAADYLAKPWDDQKLLASVENLLELGASTREVSRLHEQRRRAVRELEARYDLRGLVFASEPMTRVVELACHVARADVPVLIVGPNGAGKEKIAEIVQANSAVKSGPFVTLNCGALPTELIEAELFGADAGAYTGANKMREGKFEAADGGTLFLDEIGNLPPAGQMKLLRVLETGRFERLGSNRERQVRVRVISATNADLPAMIRDGRFREDLYYRLNTIQIAIAPLGERRDDVLPLARHFLADNPLAAGKRLSEDAERALLAHPWPGNVRELRNTLQRAALLARGDSIAAADLGLPAAAATAAAAQAAGAEEPDRAAIEAAIERAGGVLAQAAGELGLSRQALYRRLDRLGIKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD29</accession>
    <name>A0A0S2DD29_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">DNA-directed RNA polymerase subunit omega</fullName>
            <shortName evidence="11">RNAP omega subunit</shortName>
            <ecNumber evidence="2 11">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">RNA polymerase omega subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 11">Transcriptase subunit omega</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">rpoz</name>
        <name evidence="11 13" type="synonym">rpoZ</name>
        <name evidence="14" type="ORF">BV903_19755</name>
        <name evidence="16" type="ORF">D9T17_22715</name>
        <name evidence="15" type="ORF">FE772_05210</name>
        <name evidence="12" type="ORF">GLE_0911</name>
        <name evidence="13" type="ORF">LEN_4049</name>
        <name evidence="17" type="ORF">SAMN05421681_11633</name>
    </gene>
    <organism evidence="12 18">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 18" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 18">C3</strain>
        </source>
    </reference>
    <reference evidence="21" key="2">
        <citation type="journal article" date="2016" name="DNA Res." volume="0" first="0" last="0">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer, Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">M497-1</strain>
        </source>
    </reference>
    <reference evidence="17 19" key="3">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">ATCC 29487</strain>
        </source>
    </reference>
    <reference evidence="13 21" key="4">
        <citation type="journal article" date="2017" name="DNA Res." volume="24" first="169" last="177">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
            <dbReference type="PubMed" id="28065880"/>
            <dbReference type="DOI" id=".1093/dnares/dsw055"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 21">M497-1</strain>
        </source>
    </reference>
    <reference evidence="14 20" key="5">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 20">B25</strain>
        </source>
    </reference>
    <reference evidence="16 22" key="6">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 22">OH11</strain>
        </source>
    </reference>
    <reference evidence="15 23" key="7">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 23">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 11">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the RNA polymerase subunit omega family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2 11"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP014940">
        <property type="protein sequence ID" value="BAV99536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000057">
        <property type="protein sequence ID" value="OPD62226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000056">
        <property type="protein sequence ID" value="ROU04661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNOG01000016">
        <property type="protein sequence ID" value="SDY28969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_RCTY01000056.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0911"/>
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        <property type="protein sequence ID" value="ALN56269"/>
        <property type="gene ID" value="GLE_0911"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAV99536">
        <property type="protein sequence ID" value="BAV99536"/>
        <property type="gene ID" value="LEN_4049"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62226">
        <property type="protein sequence ID" value="OPD62226"/>
        <property type="gene ID" value="BV903_19755"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY28969">
        <property type="protein sequence ID" value="SDY28969"/>
        <property type="gene ID" value="SAMN05421681_11633"/>
    </dbReference>
    <dbReference type="KEGG" id="lem:LEN_4049"/>
    <dbReference type="KEGG" id="lez:GLE_0911"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000183696">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000218824">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00366">
        <property type="entry name" value="RNApol_bact_RpoZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003716">
        <property type="entry name" value="DNA-dir_RNA_pol_omega"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006110">
        <property type="entry name" value="Pol_omega/Rpo6/RPB6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036161">
        <property type="entry name" value="RPB6/omega-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34476">
        <property type="entry name" value="PTHR34476"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01192">
        <property type="entry name" value="RNA_pol_Rpb6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01409">
        <property type="entry name" value="RNA_pol_Rpb6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63562">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00690">
        <property type="entry name" value="rpoZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="6 11 12" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 11 12" id="KW-0808">Transferase</keyword>
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        <source>
            <dbReference type="ARBA" id="ARBA00006711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN56269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="BAV99536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="OPD62226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="QCW25153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ROU04661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="SDY28969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000183696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000218824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="99" mass="11076" checksum="50D233A5ECE15CA8" modified="2016-02-17" version="1">MARITVEDCLEVVPNRFELVMLAAKRARQLANGVEPQLDNSEANDKPTVLALREIAARQVNPDYIDAVEKAERERKEREALEWAAAEVVADDDLSKGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDH3</accession>
    <name>A0A0S2DDH3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_06865</name>
        <name evidence="3" type="ORF">GLE_1273</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
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            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242285" evidence="2">
        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="247" mass="26078" checksum="C09080E398C9FF28" modified="2016-02-17" version="1">MSATRVAAALACALALAGCQREAAAPAPKTPAPAAAPVSASASAATIAAGDAPQQPALAPVSDYVLPGALAPDLGVEQLRQLFGADNVAIDERLPGAEGEEFRGVRLFDGDPTRRARVYFQDSEKLRGLSIVVVDEPRSRWRLDNGLKMGQTLSELTRLNGKPLRFFGLDWDYGGVVSDWNGGALAPEDGDPVRRNARLGLAEDAPTQAQVPAGDGEFSSDDKRYPEQGRLLRVGELSVSFPGEDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDI4</accession>
    <name>A0A0S2DDI4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1224</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56581">
        <property type="protein sequence ID" value="ALN56581"/>
        <property type="gene ID" value="GLE_1224"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="42" mass="4900" checksum="5101401FD026CE2E" modified="2016-02-17" version="1">MDARVRRRGMDAPYGASPRPVLYLVAFDLKQAFFFGYFLLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDR7</accession>
    <name>A0A0S2DDR7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Membrane protein, AsmA family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_1114</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
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            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="GLE_1114"/>
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    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
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        <location>
            <begin position="41"/>
            <end position="154"/>
        </location>
    </feature>
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        <location>
            <begin position="215"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="664" mass="71339" checksum="0BCA69BFE9960AC3" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDS9</accession>
    <name>A0A0S2DDS9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Surface antigen family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_20820</name>
        <name evidence="4" type="ORF">FE772_06915</name>
        <name evidence="2" type="ORF">GLE_1285</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
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        </lineage>
    </organism>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD62005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW25435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946659.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000064.1"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN56642">
        <property type="protein sequence ID" value="ALN56642"/>
        <property type="gene ID" value="GLE_1285"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62005">
        <property type="protein sequence ID" value="OPD62005"/>
        <property type="gene ID" value="BV903_20820"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1285"/>
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    <dbReference type="OrthoDB" id="1861716at2"/>
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    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594988" evidence="1">
        <location>
            <begin position="23"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="231" mass="24369" checksum="890C7E516312B591" modified="2016-02-17" version="1">MNRSLVTVLGLALAAATGIASAQSYPSGSGNYSGGYDNGSPSYSSQVDFARVVRVDPVFETYSSQPASAPRCYERPTYVQGDGYYNDGYSNGNGGYNDGYTDQYGSQRRSAGTEGGRTAATVVGGIVGAVLGSKVGGGSARYATSAIGSMVGGMAGRSIYEQSKRSQEPPRTGTVRVCDPVPANGYGNSYANERSVTAYDVTYEYAGKTYRTRTDHNPGDRIRVRVDVRPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDV5</accession>
    <name>A0A0S2DDV5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HNH endonuclease domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1317</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946683.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1317"/>
    <dbReference type="EnsemblBacteria" id="ALN56674">
        <property type="protein sequence ID" value="ALN56674"/>
        <property type="gene ID" value="GLE_1317"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1317"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1301"/>
    <dbReference type="OMA" id="KCLHCNA"/>
    <dbReference type="OrthoDB" id="1843957at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="129" mass="13932" checksum="E91529BF46197BEA" modified="2016-02-17" version="1">MRSALRRRLLQAARTDALATLDGDVWRSRCLHCRRALAVRADGEALGATSLEHVVPSVWFGRRAAAALTARVGEDADDPRNLALACAPCNHGKGCSHDARGPGDARAREVVAALLDTRLLRWREPDAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE73</accession>
    <name>A0A0S2DE73_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PKHD-type hydroxylase FE772_06745</fullName>
            <ecNumber evidence="7">1.14.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">FE772_06745</name>
        <name evidence="9" type="ORF">GLE_1248</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="7">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <dbReference type="EC" id="1.14.11.-" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946626.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1248"/>
    <dbReference type="EnsemblBacteria" id="ALN56605">
        <property type="protein sequence ID" value="ALN56605"/>
        <property type="gene ID" value="GLE_1248"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1248"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1232"/>
    <dbReference type="OMA" id="FPPLFNC"/>
    <dbReference type="OrthoDB" id="1139586at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016706">
        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00657">
        <property type="entry name" value="Hydroxyl_YbiX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041097">
        <property type="entry name" value="PKHD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023550">
        <property type="entry name" value="PKHD_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41536">
        <property type="entry name" value="PTHR41536"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18331">
        <property type="entry name" value="PKHD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 10" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0847">Vitamin C</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="8">
        <location>
            <begin position="78"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW25401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="228" mass="25196" checksum="DE94E27DCE10696A" modified="2016-02-17" version="1">MLLHVPKVLTAEQVAHCRARLDQAGWADGRITAGHQSAKAKDNAQLPETDPAARELGALILDALSRNSTFFSAALPQRVYPPLFNRYAGGQSFGFHVDNAIRYDRSRGGMDAVRTDLSATLFLSAPDEYDGGELVIEDTYGSHNVKLPAGDLVLYPGTSLHKVTPVTRGVRTASFFWIQSLLAEDAQRRLMFELDVSIRRLSADVPEHPALVQLTGVYHNLLRRWSQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE77</accession>
    <name>A0A0S2DE77_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_07870</name>
        <name evidence="1" type="ORF">GLE_1500</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56857">
        <property type="protein sequence ID" value="ALN56857"/>
        <property type="gene ID" value="GLE_1500"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1500"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1481"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="97" mass="10335" checksum="928FB3D4B7B410BB" modified="2016-02-17" version="1">MDFATLKAAWPWTGIVGCPGRFVLNDARFVLTPADLLGPDVPVSEHHSPSARDVVLVARFADGGLISYRRPDGGCLHTLNTPEGLARKLAQLAIASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEE8</accession>
    <name>A0A0S2DEE8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Polyketide cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_12665</name>
        <name evidence="4" type="ORF">FE772_08225</name>
        <name evidence="2" type="ORF">GLE_1580</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000031">
        <property type="protein sequence ID" value="OPD63567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946893.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1580"/>
    <dbReference type="EnsemblBacteria" id="ALN56937">
        <property type="protein sequence ID" value="ALN56937"/>
        <property type="gene ID" value="GLE_1580"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63567">
        <property type="protein sequence ID" value="OPD63567"/>
        <property type="gene ID" value="BV903_12665"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1580"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1560"/>
    <dbReference type="OMA" id="TNRKMTI"/>
    <dbReference type="OrthoDB" id="1529329at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019587">
        <property type="entry name" value="Polyketide_cyclase/dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10604">
        <property type="entry name" value="Polyketide_cyc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="361" mass="39782" checksum="BBC944DA63E594E9" modified="2016-02-17" version="1">MTRLIEILISLAIVAVLFLVVGIVLPSSRHLSHSVETNRKLTIVFDTLNSLRRFKEWNPLAARDPNMEIKLVGKEEGVGARLEYSSKERGLGQGSWEIVKSEPGKLVGYKITNPERGENKRSEFTLKPTGRNNRNVEITQTYDVDYGFNLLGRYSGLYVSSSVGEDIKMGLSRLSNLLATVPNYDYAKLSETDPNNAPKVAERPAENILSVNAAVERNNDKIKGQIHANMEWINKVIAANGLEAVGPVRIVTNEFGTETYDFDTVQVVRKKGDTATGDATALEVKVEGPVKASLLPASKVVVATSGGHNFAALPPVRDAVRAWAMTRGYSTTDRPYESWKAGIDQSFDPALGQFDVYWPVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEQ6</accession>
    <name>A0A0S2DEQ6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1772</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57126">
        <property type="protein sequence ID" value="ALN57126"/>
        <property type="gene ID" value="GLE_1772"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1772"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1747"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="77" mass="7931" checksum="5F6900ED36EBFCC7" modified="2016-02-17" version="1">MHAPSARRGDPAQDHGVEMDMNREKAEQVAAHLAAGMLASGQYAMSEDTGGDAEFVASLYNAIVDKLVAARAGDAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEV2</accession>
    <name>A0A0S2DEV2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Integral membrane protein DUF6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1756</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1756"/>
    <dbReference type="EnsemblBacteria" id="ALN57111">
        <property type="protein sequence ID" value="ALN57111"/>
        <property type="gene ID" value="GLE_1756"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1756"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1732"/>
    <dbReference type="OMA" id="NDAMGKW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="17"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="158"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="308" mass="32934" checksum="55D64C28FB785D9A" modified="2016-02-17" version="1">MSAGAPAVSTTQPMRAAGLMLASTLSFGIMAIAIRLASQSLHTFEVAFFRNLFGLMAVLPLLLSARRAELRTRQLPKYFVRCAIGMVSMLCGFWAIGHLPLAQAISLTYSTPIFVTIAAALFLHEQVRARRWAAVAAGFLGVLVIVRPGSTEFSVDSLAALAAAVLGGVISIQIKQLSRIDSANTIVLYTYAFWVPMSLIPALFVWQWPQGVAWVWIVAAGVFGTGGQVLWTHALKLGEVSALTPISFVQLPLVSVAGWLWFHETLDRYTVIGAAIILGSNAYIAHREALLARKKASAAATAGAAPGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEX5</accession>
    <name>A0A0S2DEX5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription-repair-coupling factor</fullName>
            <shortName evidence="8">TRCF</shortName>
            <ecNumber evidence="8">3.6.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">mfd</name>
        <name evidence="11" type="ORF">GLE_1619</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the C-terminal section; belongs to the helicase family. RecG subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the N-terminal section; belongs to the UvrB family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946926.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1619"/>
    <dbReference type="EnsemblBacteria" id="ALN56976">
        <property type="protein sequence ID" value="ALN56976"/>
        <property type="gene ID" value="GLE_1619"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1619"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1600"/>
    <dbReference type="OMA" id="WAPPCRE"/>
    <dbReference type="OrthoDB" id="234717at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000716">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair, DNA damage recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00969">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036101">
        <property type="entry name" value="CarD-like/TRCF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003711">
        <property type="entry name" value="CarD-like/TRCF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004576">
        <property type="entry name" value="Mfd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037235">
        <property type="entry name" value="TRCF-like_C_D7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005118">
        <property type="entry name" value="TRCF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02559">
        <property type="entry name" value="CarD_CdnL_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03461">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01058">
        <property type="entry name" value="CarD_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00982">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141259">
        <property type="entry name" value="SSF141259"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143517">
        <property type="entry name" value="SSF143517"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00580">
        <property type="entry name" value="mfd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="621"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="803"/>
            <end position="957"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN56976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1152" mass="127291" checksum="9B25574092545B17" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFB5</accession>
    <name>A0A0S2DFB5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57086">
        <property type="protein sequence ID" value="ALN57086"/>
        <property type="gene ID" value="GLE_1731"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1731"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="44" mass="4895" checksum="D69CDA1EF85E2E5B" modified="2016-02-17" version="1">MHVSPRARARKRGSQKKRPAHGGAFASTALQARRRGWLGERISP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFC3</accession>
    <name>A0A0S2DFC3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1881</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947117.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57233">
        <property type="protein sequence ID" value="ALN57233"/>
        <property type="gene ID" value="GLE_1881"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1881"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1852"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595089" evidence="2">
        <location>
            <begin position="24"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="79" mass="8225" checksum="5471BD41BB1026CC" modified="2016-02-17" version="1">MRTTLAFALLIAATATFSAPSFAREPSYQACSPPFSGPPFCQPPLSQVELSTSTGKRAATKAPTTQAPRSAPQPSTAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFL3</accession>
    <name>A0A0S2DFL3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dgpfaetke domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2017</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YciI family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947215.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2017"/>
    <dbReference type="EnsemblBacteria" id="ALN57367">
        <property type="protein sequence ID" value="ALN57367"/>
        <property type="gene ID" value="GLE_2017"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2017"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1982"/>
    <dbReference type="OMA" id="KEVVGGW"/>
    <dbReference type="OrthoDB" id="2051456at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII" evidence="2">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="119" mass="12916" checksum="D36209B75D87E0EC" modified="2016-02-17" version="1">MRFLSLIRIDETTARPPSEQLLADMGRLMEQMTREGVLIQTAGLQPSAHGARLRLRGGRIAATDGPFAESKEVIGGYALLEAADLDEALAHTRRFLAVHGEGWDIECEVRPLMADGACG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG17</accession>
    <name>A0A0S2DG17_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NAD dependent epimerase/dehydratase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_2210</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947365.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2210"/>
    <dbReference type="EnsemblBacteria" id="ALN57559">
        <property type="protein sequence ID" value="ALN57559"/>
        <property type="gene ID" value="GLE_2210"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2210"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2172"/>
    <dbReference type="OMA" id="DTFYHHE"/>
    <dbReference type="OrthoDB" id="1566711at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013549">
        <property type="entry name" value="DUF1731"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010099">
        <property type="entry name" value="SDR39U1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08338">
        <property type="entry name" value="DUF1731"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01777">
        <property type="entry name" value="yfcH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Epimerase" evidence="3">
        <location>
            <begin position="189"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1731" evidence="4">
        <location>
            <begin position="437"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="511" mass="54497" checksum="3F32F6C46F781BC9" modified="2016-02-17" version="1">MDLHTLFLSLLLLQIAMGALDTIAHHEVMEKLANRRSAALELKLHSARGFVYGALFLVFAWLRPQGLWLAAVWLLVLIEVGITLWDFVVEDATRLLPNTERVLHTVLAVNGGAMFAVYALATRGDWALPSALAPAAHGTLLQSAMSWALTAAALGIAASAVRDGLAARANAAEPAPRPLLAQHPQQHFLVSGGTGFIGTALVEGLLAGGHRITVLSRDPRRAALRFGGRARCIADTAELRDDERIDVVVNLAGAPVVGPRWTPQRKRALLASRIGTTDALRAWCDRASVKPALWLQASAVGLYGAHARSAPEQREFAPVPGDFPSALCAAWERAAAPVGERGVRLATMRLGLVLHRSGGLLPMLSLAAALGGAARLGDGRQWFAWVHLDDVLRFVEYAVEHAGVRGPYNLVAPGGCTQAEFTRELARSLHRPAWLAMPAAPLRLALGEMATMLLDGPVAAPQRLTDQRFVFAHPVLASALRGAHAGLARDLRSDYVGVGHPGEGHGTVATH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG81</accession>
    <name>A0A0S2DG81_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF11 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_11005</name>
        <name evidence="3" type="ORF">GLE_2181</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2181"/>
    <dbReference type="EnsemblBacteria" id="ALN57530">
        <property type="protein sequence ID" value="ALN57530"/>
        <property type="gene ID" value="GLE_2181"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2181"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2143"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01345">
        <property type="entry name" value="DUF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726652" evidence="1">
        <location>
            <begin position="19"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="domain" description="DUF11" evidence="2">
        <location>
            <begin position="468"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="559" mass="56529" checksum="3B4D5A76197E0620" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGD5</accession>
    <name>A0A0S2DGD5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57400">
        <property type="protein sequence ID" value="ALN57400"/>
        <property type="gene ID" value="GLE_2050"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2050"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2015"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="44" mass="4683" checksum="0A08517BF1CC86A8" modified="2016-02-17" version="1">MGERPRINAGGRGVGGYGRVCRGCVVAVAACAALQELRRLRIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGI3</accession>
    <name>A0A0S2DGI3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">IS30 family transposase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">ISMsm8, transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FE772_08375</name>
        <name evidence="5" type="ORF">GLE_1611</name>
        <name evidence="6" type="ORF">GLE_2292</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for the transposition of the insertion element.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transposase IS30 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946920.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56968">
        <property type="protein sequence ID" value="ALN56968"/>
        <property type="gene ID" value="GLE_1611"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57641">
        <property type="protein sequence ID" value="ALN57641"/>
        <property type="gene ID" value="GLE_2292"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1611"/>
    <dbReference type="KEGG" id="lez:GLE_2292"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1591"/>
    <dbReference type="OrthoDB" id="1780129at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025246">
        <property type="entry name" value="IS30-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001598">
        <property type="entry name" value="Transposase_IS30_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13936">
        <property type="entry name" value="HTH_38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01043">
        <property type="entry name" value="TRANSPOSASE_IS30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="4">
        <location>
            <begin position="188"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW28679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="353" mass="40517" checksum="C25F0EBD477475A7" modified="2016-02-17" version="1">MGQAYSHLSAEERGAIMVLIAQGASGRRIAQVLGRAQSTIARELRRNGYRSDLAAPLRGRPRLEPGYDATRAGRRAQRLRRRARVRRKLQRDTPLWRRVRYWLERCWSPQQIADKLRDLYPDRPWLHVSHETIYTAIYAMPRGELRRQVTRLLRQGRKSGRRTRQGGDARGHLPDLPNIRLRPPAAHERLMPGHWEGDLIVGAYNRSAIGVLVCRRTLYVKLVKLEDATARTVLEAFGSAFEGVTPQLRQTLTYDQGKEMALHRQLSERTGLSIYFADPHSPWQRGICENTNGLLRQYFPKGTDLSVHSAQRLKEVAWEMNNRPRRSLGVRSPVEVLYEELKTLQAQGDALGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGV5</accession>
    <name>A0A0S2DGV5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nuclear transport factor 2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_11495</name>
        <name evidence="1" type="ORF">GLE_2286</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947422.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2286"/>
    <dbReference type="EnsemblBacteria" id="ALN57635">
        <property type="protein sequence ID" value="ALN57635"/>
        <property type="gene ID" value="GLE_2286"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2286"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2251"/>
    <dbReference type="OMA" id="PDSARHY"/>
    <dbReference type="OrthoDB" id="1723628at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="160" mass="17486" checksum="560D36A28AD460A9" modified="2016-02-17" version="1">MFTLFAIDRTQPLRSAARAGARMGWLAAALLALAACGGGSPEQRLRASMTQLQDAIQARDAKAVRAQLADDFVGPQGLDREGARRLAAASFLRYRDVWVRVAAPRFEVKGDRATVEFEAALGGGAGNALPEAAQLYQVRTGWRERDGEWRMISAEWTPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH02</accession>
    <name>A0A0S2DH02_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta glucanase A</fullName>
            <ecNumber evidence="4">3.2.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">gluA</name>
        <name evidence="4" type="ORF">GLE_2518</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.2.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2518"/>
    <dbReference type="EnsemblBacteria" id="ALN57867">
        <property type="protein sequence ID" value="ALN57867"/>
        <property type="gene ID" value="GLE_2518"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2518"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2481"/>
    <dbReference type="OMA" id="SWPAIWM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="GH16"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="3">
        <location>
            <begin position="112"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="345" mass="38819" checksum="6078F5D9D58AE741" modified="2016-02-17" version="1">MHEPLRLRGRRAAPARAVVQHADRSRRSGSSTGPRLECELAQQTQARASRSLTALSLQDSVGPSRGATGVRGDGGPTAPAVSPRRQQRYDTMKRLMKGLVLCFACAFAGSAAAQSWQLVWSDEFNGSIGPSWAFETGNGSGGWGNNERQYYRRENAGIENNALVITARRQDFNGFRYTSARMKTQGLRNVRYGKIEARMRLPSFMGAWPAFWMLGANLPQVGWPDSGEIDIMEHINNENRSYGTIHWRDHNGNYAQYGGNTAVGVADWHVYSVEWDANAIRWYVDGNKFHEANIQNNINGTEEFHRDFFVLLNFAIGGNWPGFNIDESKLPAKMHVDYVRVYRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH29</accession>
    <name>A0A0S2DH29_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2307</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57656">
        <property type="protein sequence ID" value="ALN57656"/>
        <property type="gene ID" value="GLE_2307"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2307"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2272"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="62" mass="7053" checksum="E7DE90773F7DA2A2" modified="2016-02-17" version="1">MDRTHFKQRSDVHTADAATTPRVWAEGHAVTKVTATFSRFGRRAPTLDLRIRRSPQARGYEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH54</accession>
    <name>A0A0S2DH54_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sugar MFS transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Transporter, major facilitator family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_12720</name>
        <name evidence="7" type="ORF">GLE_2533</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947614.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2533"/>
    <dbReference type="EnsemblBacteria" id="ALN57882">
        <property type="protein sequence ID" value="ALN57882"/>
        <property type="gene ID" value="GLE_2533"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2533"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2495"/>
    <dbReference type="OMA" id="CTSVMWG"/>
    <dbReference type="OrthoDB" id="1121832at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="170"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="215"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="306"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="7"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW26399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="410" mass="44159" checksum="13DD05F3188EE3B6" modified="2016-02-17" version="1">MKHRPLIISYLLLIWFAISFITNLIGPLMPIAIDDFKLSLTMAGFMPFSFFLAYGLISIPGGVLIEARGTRFTLFAAFALNFVGALAIAVVPGYASVVAGLFVIGLGMALLQVVINPLMRTAGGEQHFAFFSVMAQLVFGLASFLSPLAFKFYMQRPGVDGQPLAWLTFYWFFSAAFVLLAALNWKLPLPAVALKDDERAGSREAYLSLLRRRDVRLFFLAIVAYVGTEQSLANWMSQFLHSYHGFSATQEGAVAVSRFWGLMSLGCLVGLGLLKLLDSKWVLAIFSTLAIACLALALLGPAAVSLLAFPAAGFFLSVMFSVIFSLGLNSVSQHHGAFSGILCSGILGGAIVPLLIGILADRWGLRAGLSLVFLPLLYILSVAAWARPLVRNQTVYSAKSTPASSTPAPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHA9</accession>
    <name>A0A0S2DHA9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoglycerol transferase I</fullName>
            <ecNumber evidence="2">2.7.8.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mdoB</name>
        <name evidence="2" type="ORF">GLE_2653</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.7.8.20" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58001">
        <property type="protein sequence ID" value="ALN58001"/>
        <property type="gene ID" value="GLE_2653"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2653"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2612"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008960">
        <property type="term" value="F:phosphatidylglycerol-membrane-oligosaccharide glycerophosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="304"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="334"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="375"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="688" mass="73063" checksum="C85D661ED706BA05" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHK3</accession>
    <name>A0A0S2DHK3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid adenylation domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_2558</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947635.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2558"/>
    <dbReference type="EnsemblBacteria" id="ALN57907">
        <property type="protein sequence ID" value="ALN57907"/>
        <property type="gene ID" value="GLE_2558"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2558"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2518"/>
    <dbReference type="OMA" id="PAAFHCG"/>
    <dbReference type="OrthoDB" id="572620at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043604">
        <property type="term" value="P:amide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1830">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010060">
        <property type="entry name" value="NRPS_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041464">
        <property type="entry name" value="TubC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044894">
        <property type="entry name" value="TubC_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18563">
        <property type="entry name" value="TubC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01720">
        <property type="entry name" value="NRPS-para261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="1066"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="2550"/>
            <end position="2624"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="6">
        <location>
            <begin position="4034"/>
            <end position="4109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1049"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1100"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="2585"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="4069"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN57907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="4127" mass="446573" checksum="908CB4D8B57F8F03" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHQ8</accession>
    <name>A0A0S2DHQ8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2474</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947563.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57823">
        <property type="protein sequence ID" value="ALN57823"/>
        <property type="gene ID" value="GLE_2474"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2474"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2436"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="65" mass="6938" checksum="EB7F213084E4B166" modified="2016-02-17" version="1">MGRAVADDVALEHISERRPAADIGLAGGIAAWVRRKPAHAFALAVAAGWLLGKISRVAQGRRRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHZ7</accession>
    <name>A0A0S2DHZ7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">UTP--glucose-1-phosphate uridylyltransferase</fullName>
            <ecNumber evidence="3 5">2.7.7.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">UDP-glucose pyrophosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">galU</name>
        <name evidence="9" type="ORF">D9T17_16655</name>
        <name evidence="8" type="ORF">FE772_14560</name>
        <name evidence="7" type="ORF">GLE_2919</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">OH11</strain>
        </source>
    </reference>
    <reference evidence="8 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 12">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-alpha-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:19889"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.7.7.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the UDPGP type 2 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.9" evidence="3 5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000041">
        <property type="protein sequence ID" value="ROU05808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947910.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2919"/>
    <dbReference type="EnsemblBacteria" id="ALN58267">
        <property type="protein sequence ID" value="ALN58267"/>
        <property type="gene ID" value="GLE_2919"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2919"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2881"/>
    <dbReference type="OMA" id="KRYDVGN"/>
    <dbReference type="OrthoDB" id="1402673at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003983">
        <property type="term" value="F:UTP:glucose-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006011">
        <property type="term" value="P:UDP-glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02541">
        <property type="entry name" value="UGPase_prokaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005771">
        <property type="entry name" value="GalU_uridylyltTrfase_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43197">
        <property type="entry name" value="PTHR43197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01099">
        <property type="entry name" value="galU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="6">
        <location>
            <begin position="12"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW26692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROU05808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="300" mass="32496" checksum="E05B34E5A3F908A6" modified="2016-02-17" version="1">MPARIRKAVFPVAGLGTRFLPATKTVPKEMLPIIDRPLIQYAVDEAIEAGCDTLVFITNRYKHAVADYFDKAYELEHKLERSGKTEQLELIRNVLPPGVRAVFVTQAEALGLGHAVLCAKDVIGDEPFAVLLPDDLIWNRGGAGALKQMADASAASGASTIAVQDVPREQTGSYGIVATSNFDARQGRITAIVEKPKPEVAPSNLAVVGRYVLNPRIFELLENTTPGAGGEIQLTDAIATLLQQEAVNAYRFQGTRFDCGTHIGLIEATIRYALDHEKLSDSARQMMQSALNELGVEDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI18</accession>
    <name>A0A0S2DI18_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FMN dependent NADH:quinone oxidoreductase</fullName>
            <ecNumber evidence="6">1.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Azo-dye reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">FMN-dependent NADH-azo compound oxidoreductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">FMN-dependent NADH-azoreductase</fullName>
            <ecNumber evidence="6">1.7.1.17</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">azoR</name>
        <name evidence="9" type="ORF">FE772_14820</name>
        <name evidence="8" type="ORF">GLE_2962</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.</text>
    </comment>
    <comment type="function">
        <text evidence="6">Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 a quinone + H(+) + NADH = 2 a 1,4-benzosemiquinone + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:65952"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="ChEBI" id="CHEBI:134225"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>anthranilate + N,N-dimethyl-1,4-phenylenediamine + 2 NAD(+) = 2-(4-dimethylaminophenyl)diazenylbenzoate + 2 H(+) + 2 NADH</text>
            <dbReference type="Rhea" id="RHEA:55872"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15783"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:71579"/>
            <dbReference type="EC" id="1.7.1.17"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="5">
            <dbReference type="Rhea" id="RHEA:55874"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="6">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the azoreductase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="1.6.5.-" evidence="6"/>
    <dbReference type="EC" id="1.7.1.17" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947942.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58310">
        <property type="protein sequence ID" value="ALN58310"/>
        <property type="gene ID" value="GLE_2962"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2962"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2923"/>
    <dbReference type="OMA" id="REGWDHS"/>
    <dbReference type="OrthoDB" id="1402654at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016652">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01216">
        <property type="entry name" value="Azoreductase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003680">
        <property type="entry name" value="Flavodoxin_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023048">
        <property type="entry name" value="NADH:quinone_OxRdtase_FMN_depd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02525">
        <property type="entry name" value="Flavodoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2 6" id="KW-0288">FMN</keyword>
    <keyword evidence="4 6" id="KW-0520">NAD</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin_2" evidence="7">
        <location>
            <begin position="1"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="15"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="91"/>
            <end position="94"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="135"/>
            <end position="138"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW26729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="200" mass="20925" checksum="5C383D1B4E8C5D03" modified="2016-02-17" version="1">MNILHIDSSILGDQSVSRKLSAAIVSKLRALAPGADVVYRDLNSEPLPALTTANAAALDPAAPADNDEVRALNAALAQVLAADAIVVGAPMYNFSIPAPLKAWLDALAVPGKTFGYENGAPKGLLGAKRVIVASSRGGVYAPQTPMAALEHHENYLRAFFGFLGVTQLEFVRAEGLKMGPEQAERAVAGALEQVEQLRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI39</accession>
    <name>A0A0S2DI39_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2856</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2856"/>
    <dbReference type="EnsemblBacteria" id="ALN58204">
        <property type="protein sequence ID" value="ALN58204"/>
        <property type="gene ID" value="GLE_2856"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2856"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2818"/>
    <dbReference type="OMA" id="CASRSEM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035242">
        <property type="entry name" value="DUF5329"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17263">
        <property type="entry name" value="DUF5329"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595223" evidence="1">
        <location>
            <begin position="34"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="144" mass="15166" checksum="26CBE38DDAFE25FB" modified="2016-02-17" version="1">MAGQATLAGMNATASSFGMVLVLALAAAAPARAAPSAQAERETEHLIQALGRSGCQFERNGSWYDAAQAQAHLRKKLAYLRKRDLADTAELFIERAASESSLSGKPYHVRCGGDAATPAAAWLRARLVQLRNAKPPSPATPPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI57</accession>
    <name>A0A0S2DI57_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_06150</name>
        <name evidence="4" type="ORF">FE772_13980</name>
        <name evidence="2" type="ORF">GLE_2799</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <source>
            <dbReference type="EMBL" id="ALN58147.1"/>
        </source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
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                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 6">B25</strain>
        </source>
    </reference>
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            <end position="29"/>
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            <end position="86"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD64799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="255" mass="28068" checksum="12A3228204CA2D57" modified="2016-02-17" version="1">MKMKSHVWSTLAPLLLGLLAVFAPRPAQAQAFTCYMYYGKLVGICNTEGSQIFNKAQMIKNVGSELNKINRMKQQLEQEKARFEQLNPGSLNIGSVAGNREFGDLKPRDINEGRDETCHKGKSSVAEEQYKVCVNAVQLRNKRFNVMVQMFKDIEKRDQNIQKIRSDRAGISGPKDNGRLAGNDNASKTIDAAMMNDMQSYVATMELYTTMLKTLDDQMALLANKALANKGSVLGGVVQGAALKAGLAAAESRDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58455">
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        <property type="gene ID" value="GLE_3108"/>
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    <dbReference type="PATRIC" id="fig|69.6.peg.3065"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="57" mass="5997" checksum="F3DCF4802F176F09" modified="2016-02-17" version="1">MRSDDAHSNAVIARLFDLARNGEGDDAELRELDAQIQAGLAAAYGEGALELENPLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIT3</accession>
    <name>A0A0S2DIT3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter, ATP-binding protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="11 12">
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        <lineage>
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    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN58420">
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        <property type="gene ID" value="GLE_3073"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3073"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3033"/>
    <dbReference type="OMA" id="MYEDALF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
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        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
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        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
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        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="195"/>
            <end position="222"/>
        </location>
    </feature>
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        <location>
            <begin position="293"/>
            <end position="316"/>
        </location>
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            <begin position="55"/>
            <end position="354"/>
        </location>
    </feature>
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        <location>
            <begin position="389"/>
            <end position="629"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="423"/>
            <end position="430"/>
        </location>
        <ligand>
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        <source>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN58420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="635" mass="70401" checksum="DEB592D5300A0195" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIT8</accession>
    <name>A0A0S2DIT8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Heme exporter protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ccmB</name>
        <name evidence="14" type="ORF">GLE_2827</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 12">Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the CcmB/CycW/HelB family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2827"/>
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        <property type="protein sequence ID" value="ALN58175"/>
        <property type="gene ID" value="GLE_2827"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2827"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2785"/>
    <dbReference type="OMA" id="VKCLAHW"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
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            <end position="54"/>
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        </source>
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    <sequence length="234" mass="23980" checksum="0B8EFE2D4F843744" modified="2016-02-17" version="1">MSPAADAALAPGLIGSARALIARDLRLLWRRRGDALQPALFALLTVMLFALALGGERAALAKVAAGVLWLACLLAGLLALDSLFRGDAEDGSLEQWMLAPVPLGWLVAVRTLVHWATTSLPLLLAAPVLGELLYLPRDQLPVLLASLALGTPVLSLLGAVVAALTVGMRRSGILVALLALPLYVPVLVFGAGSVARASQGLDPVGGLLLLAAMLAVALLLAPLAAAAAIRIALN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIU9</accession>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
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        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW26840.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="599" mass="66432" checksum="045CC95A497270C7" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIZ9</accession>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl_trans_N" evidence="1">
        <location>
            <begin position="67"/>
            <end position="176"/>
        </location>
    </feature>
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        <location>
            <begin position="207"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="603" mass="65903" checksum="925A4E1793475F4D" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ21</accession>
    <name>A0A0S2DJ21_LYSEN</name>
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        <submittedName>
            <fullName evidence="4">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
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    </gene>
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    </organism>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    <dbReference type="EnsemblBacteria" id="ALN58255">
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        <property type="gene ID" value="GLE_2907"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2907"/>
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    <dbReference type="OMA" id="RFFANNG"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="TPR_21"/>
    </dbReference>
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        <property type="entry name" value="YfgM"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="YfgM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TPR_21" evidence="2">
        <location>
            <begin position="18"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="209" mass="22333" checksum="730864C23D18BC30" modified="2016-02-17" version="1">MAIDDLLDEHEQSERVLSWLRANGAGLIGGIALGLAAIGGWKWWGNHQVEQNAQASAQYQSAVDAVQAKDKAAEAKVKALPEGMYHTLAALELAKQQVEANQGAAAIATLRAIKTDDAAMAEIVSQRLARLLVDTKQPAEALKLLAQSSQPLAIEVRGDAQLALGKQELARKEYTDALAKLDEASPRRRLLELKLTEAGGTPAKPEAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJD7</accession>
    <name>A0A0S2DJD7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3278</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3278"/>
    <dbReference type="EnsemblBacteria" id="ALN58624">
        <property type="protein sequence ID" value="ALN58624"/>
        <property type="gene ID" value="GLE_3278"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3278"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3231"/>
    <dbReference type="OMA" id="FQLEPWT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="326" mass="35728" checksum="861C9FC4917932D1" modified="2016-02-17" version="1">MGAGILAASILIVGCSQQADPAAAQAPKPAEPAAAAPAAGDAAVFFDDFNYPDLAAFQGNGWKARTETGHPGIKGATWSAEGLSFHADIADTHGGAVRMSSVTNGKADKTRQTQFCHARKYREGTYAARIFFRDAPSYGPDGDEVIQTFYAISPLKAPMDKNYSETDFEYLPNGGWGENSKPAMWTTSWDTFQLEPWTKVNEFTRHEGSYAGWRTLVLTVADKQLKYYVDGKLFSEHSSAVYPEDFMSINFNLWFMPKGADGSLGPVDSPEMREYQEDIDWVFFREGAALSTADVEKQVAELRGKQVAHLDNVKEQNPPLPSPCGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJR3</accession>
    <name>A0A0S2DJR3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pantothenate synthetase</fullName>
            <shortName evidence="5">PS</shortName>
            <ecNumber evidence="5">6.3.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Pantoate--beta-alanine ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Pantoate-activating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">panC</name>
        <name evidence="7" type="ORF">FE772_15775</name>
        <name evidence="6" type="ORF">GLE_3174</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>(R)-pantoate + ATP + beta-alanine = (R)-pantothenate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10912"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:29032"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57966"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantothenate from (R)-pantoate and beta-alanine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="5">The reaction proceeds by a bi uni uni bi ping pong mechanism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the pantothenate synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.1" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948097.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3174"/>
    <dbReference type="EnsemblBacteria" id="ALN58520">
        <property type="protein sequence ID" value="ALN58520"/>
        <property type="gene ID" value="GLE_3174"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3174"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3129"/>
    <dbReference type="OMA" id="CNHKLEP"/>
    <dbReference type="OrthoDB" id="1661843at2"/>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004592">
        <property type="term" value="F:pantoate-beta-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00560">
        <property type="entry name" value="PanC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00158">
        <property type="entry name" value="PanC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003721">
        <property type="entry name" value="Pantoate_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042176">
        <property type="entry name" value="Pantoate_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21299:SF1">
        <property type="entry name" value="PTHR21299:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02569">
        <property type="entry name" value="Pantoate_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00018">
        <property type="entry name" value="panC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 5" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="30"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="149"/>
            <end position="152"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>(R)-pantoate</name>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="186"/>
            <end position="189"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW26883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="283" mass="31330" checksum="2769E05384BC7147" modified="2016-02-17" version="1">MLTVDQLGALRSTLQAWRASGQRVAFVPTMGNLHEGHHSLIRLARERADRVVASVFVNPTQFGPNEDFGRYPRTPDADADGLRAAGCDLLWRPSVETMYPYGAQRTVRIAVPDVTETLEGAHRPGHFDGVATVVARLFNQVRPDVAVFGRKDYQQLAVIRYLVRDLAFPIELVAAPTRRDADGLALSSRNQYLSEDERARAPQIHRTLQWIREAVQAGQGREAVEAEAARRLTDAGFEVDYAVLRRPDLSLPEAGDAGDGERVALVAARLGRTRLIDNLEFVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJY4</accession>
    <name>A0A0S2DJY4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ</fullName>
            <ecNumber evidence="4">2.1.1.200</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA Cm32/Um32 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">trmJ</name>
        <name evidence="7" type="ORF">GLE_3507</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>S-adenosyl-L-methionine + uridine(32) in tRNA = 2'-O-methyluridine(32) in tRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42936"/>
            <dbReference type="Rhea" id="RHEA-COMP:10107"/>
            <dbReference type="Rhea" id="RHEA-COMP:10290"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74478"/>
            <dbReference type="EC" id="2.1.1.200"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>cytidine(32) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(32) in tRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42932"/>
            <dbReference type="Rhea" id="RHEA-COMP:10288"/>
            <dbReference type="Rhea" id="RHEA-COMP:10289"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.200"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.200" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3507"/>
    <dbReference type="EnsemblBacteria" id="ALN58852">
        <property type="protein sequence ID" value="ALN58852"/>
        <property type="gene ID" value="GLE_3507"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3507"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3451"/>
    <dbReference type="OMA" id="PIMNLSH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004384">
        <property type="entry name" value="RNA_MeTrfase_TrmJ/LasT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42786">
        <property type="entry name" value="PTHR42786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00050">
        <property type="entry name" value="rRNA_methyl_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="6">
        <location>
            <begin position="57"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="313" mass="32662" checksum="B2613A67F5F8347F" modified="2016-02-17" version="1">MNHDPREPAPTAQATENANPNANSEANPLEAASAPAPAPAPAPGDEPAAIDPAMARIRVVLVGTQHPGNIGSAARAMKTMGLSRLVLAAPEKAPDRDSYALAAGADDVLAAATVVPDLAAAVADCHFVLGCTARSRRIALEQFDPRQAAALCDARARAGSEVALVFGRERTGLENHELQLCHAAVHIPANPGYSSLNLAAAVQVLSYELRMASLAASAPAAAPAPLPAAIVGDGGDRREPPASHAQMEGFFGQLGQALDAIDFHKGRTPEAAMHKLRRLFLRAQLDEREVRLLRGVLADVERTAMLLAAAQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK33</accession>
    <name>A0A0S2DK33_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_16890</name>
        <name evidence="1" type="ORF">GLE_3424</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948285.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3424"/>
    <dbReference type="EnsemblBacteria" id="ALN58769">
        <property type="protein sequence ID" value="ALN58769"/>
        <property type="gene ID" value="GLE_3424"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3424"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3374"/>
    <dbReference type="OrthoDB" id="966604at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="244" mass="26056" checksum="1F8276C9A414AF9C" modified="2016-02-17" version="1">MIEWSKLQDAYGPADAVPALLAALDPDPAAEVWTELWSRICHQGTVYSASYPALPALLDAARGWAPPARVMPVSLAATILASPQTGADERARHAALAAELRSLAADSLRAPALSRADIVCLQQAVLLLDGEPWAEQYDRLLSGELDGQCPACATDLMVVIGEYGFFVTDQEWIHGHNERAAPIAPADPASPDDPAGLPSVGEWLWQGARRHDDAELQAWIAHLFGNGRCPACAAQWPVLEAVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK68</accession>
    <name>A0A0S2DK68_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide repeat domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3496</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948333.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3496"/>
    <dbReference type="EnsemblBacteria" id="ALN58841">
        <property type="protein sequence ID" value="ALN58841"/>
        <property type="gene ID" value="GLE_3496"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3496"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3441"/>
    <dbReference type="OMA" id="LKYSFWM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="310" mass="34517" checksum="33BA0F1CCC7CF90A" modified="2016-02-17" version="1">MSAFGHDALYRMAERYYAHGQIDAAIDALLRLLGEDADHSDAHAFLALCLVKRKRLHAAALEARRALELTPESAFAHLAAASAATAQRRYAEAEAHLQAARERSPEAAPVADAFARLYRAWGRDAQALEQARRACALDPDDPDYPALLAWLELRRGDRAQAERLAREVLAGHPEHLDALCVLGHCELARGRADSAREHAAWALQIDPTDADALTLMAAVKARQSPLLGLWWRLQSFLSAGSRTRMVLLLLGMFLIYRIALIALPQQGLAQWVGPISYGWLLFCAYTWIAPTLFWRSVKKELEQVRLRPGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKA3</accession>
    <name>A0A0S2DKA3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3702</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948485.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59046">
        <property type="protein sequence ID" value="ALN59046"/>
        <property type="gene ID" value="GLE_3702"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3702"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3646"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="89" mass="9197" checksum="5A11CBE7140F58B0" modified="2016-02-17" version="1">MNAHDPERPDPQSGAQPPAPAEQAPASALDPARWIHRLRNELNTASMACAAAQAVLAGGAVVKAQENLERARGACARAAALLEQAPPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKF4</accession>
    <name>A0A0S2DKF4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">rplB</name>
        <name evidence="8" type="ORF">BV903_23020</name>
        <name evidence="10" type="ORF">D9T17_09445</name>
        <name evidence="9" type="ORF">FE772_18635</name>
        <name evidence="7" type="ORF">GLE_3787</name>
    </gene>
    <organism evidence="7 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 11">C3</strain>
        </source>
    </reference>
    <reference evidence="8 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">OH11</strain>
        </source>
    </reference>
    <reference evidence="9 14" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000077">
        <property type="protein sequence ID" value="OPD61614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000023">
        <property type="protein sequence ID" value="ROU07185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948552.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3787"/>
    <dbReference type="EnsemblBacteria" id="ALN59131">
        <property type="protein sequence ID" value="ALN59131"/>
        <property type="gene ID" value="GLE_3787"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61614">
        <property type="protein sequence ID" value="OPD61614"/>
        <property type="gene ID" value="BV903_23020"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3787"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3731"/>
    <dbReference type="OMA" id="SCIELRP"/>
    <dbReference type="OrthoDB" id="961486at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01320_B">
        <property type="entry name" value="Ribosomal_L2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Rbsml_prot_L2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Ribosomal_L2_C"/>
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    </dbReference>
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        <property type="entry name" value="Ribosomal_L2_dom3"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="rplB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00467">
        <property type="entry name" value="RIBOSOMAL_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
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    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L2_C" evidence="6">
        <location>
            <begin position="124"/>
            <end position="253"/>
        </location>
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        <location>
            <begin position="224"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD61614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW27358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ROU07185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="275" mass="29916" checksum="005A6F23E0E8E846" modified="2016-02-17" version="1">MALMTFKPTSAGRRNAVRVVTPGLHKGAPHAALIEKQGKTGGRNHHGRITTRHIGGGHKQHYRIIDFKRDKEGIPARVERIEYDPNRTAHIALLCYVDGERRYIIAPKGLKDGDQVIAGRDAPIRVGNTLPLSNVPVGTTVCCVEMKPGKGAQLARAAGASAYLVAREQGYATLRLRSGEMRKVPVECRATVGEVGNDEHNLEKLGKAGAKRWRGIKPTVRGAAMNPVDHPHGGGEAKAGQGNPHPVTPWGVPTKGYKTRKNKRTTQFIVRDRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKZ8</accession>
    <name>A0A0S2DKZ8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidase</fullName>
            <ecNumber evidence="3">3.5.1.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_18510</name>
        <name evidence="2" type="ORF">GLE_3761</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.1.4" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3761"/>
    <dbReference type="EnsemblBacteria" id="ALN59105">
        <property type="protein sequence ID" value="ALN59105"/>
        <property type="gene ID" value="GLE_3761"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3761"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3705"/>
    <dbReference type="OMA" id="DMRSNNY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043864">
        <property type="term" value="F:indoleacetamide hydrolase activity"/>
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        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF75304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="1">
        <location>
            <begin position="109"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="583" mass="60648" checksum="C98CC2955A9B63D2" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL20</accession>
    <name>A0A0S2DL20_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">PKD domain/proprotein convertase P-domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">GLE_3845</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3845"/>
    <dbReference type="EnsemblBacteria" id="ALN59188">
        <property type="protein sequence ID" value="ALN59188"/>
        <property type="gene ID" value="GLE_3845"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3845"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3785"/>
    <dbReference type="OMA" id="SKWRTIM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002884">
        <property type="entry name" value="P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01483">
        <property type="entry name" value="P_proprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51829">
        <property type="entry name" value="P_HOMO_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595318" evidence="3">
        <location>
            <begin position="30"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="4">
        <location>
            <begin position="443"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="P/Homo B" evidence="5">
        <location>
            <begin position="523"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="642" mass="67195" checksum="229ADAAB961BDC80" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL65</accession>
    <name>A0A0S2DL65_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59317">
        <property type="protein sequence ID" value="ALN59317"/>
        <property type="gene ID" value="GLE_3975"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3975"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3913"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="38" mass="4319" checksum="38CE8B454B2DE0A7" modified="2016-02-17" version="1">MGFAWGFVPANSNSNIKMDSGFRRNDEARKRSSPWTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL82</accession>
    <name>A0A0S2DL82_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LPS-assembly protein LptD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lptD</name>
        <name evidence="6" type="ORF">GLE_3910</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LptD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3910"/>
    <dbReference type="EnsemblBacteria" id="ALN59252">
        <property type="protein sequence ID" value="ALN59252"/>
        <property type="gene ID" value="GLE_3910"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3910"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3847"/>
    <dbReference type="OMA" id="DYSHLDW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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    <dbReference type="GO" id="GO:0015920">
        <property type="term" value="P:lipopolysaccharide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010033">
        <property type="term" value="P:response to organic substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01411">
        <property type="entry name" value="LPS_assembly_LptD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020889">
        <property type="entry name" value="LipoPS_assembly_LptD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007543">
        <property type="entry name" value="LptD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005653">
        <property type="entry name" value="OstA-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04453">
        <property type="entry name" value="LptD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03968">
        <property type="entry name" value="LptD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0998">Cell outer membrane</keyword>
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    <keyword evidence="2" id="KW-0732">Signal</keyword>
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            <begin position="64"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="LptD" evidence="5">
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            <end position="735"/>
        </location>
    </feature>
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        <location>
            <begin position="821"/>
            <end position="844"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="844" mass="95404" checksum="4B0D2B392849C6D3" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL91</accession>
    <name>A0A0S2DL91_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4007</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948709.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59349">
        <property type="protein sequence ID" value="ALN59349"/>
        <property type="gene ID" value="GLE_4007"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4007"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3944"/>
    <dbReference type="OMA" id="GTMLDHV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025105">
        <property type="entry name" value="DUF4010"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13194">
        <property type="entry name" value="DUF4010"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="223"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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            <end position="264"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="328"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4010" evidence="2">
        <location>
            <begin position="118"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="352" mass="35609" checksum="E877589955CF7A56" modified="2016-02-17" version="1">MYKSLLLPLSGHDGDADALYVATRLTTEAAWLLTFLIGALAMREAAVSAALGVALAILLAAREHLHRFSRHWIGHEELRGLLLLAACAFIVLPLLPDRALDPWGAINPHQLWTLAVGVMIVSAAGYLATRVLGARAGLPIAGLAGGFVSSTATVAAMAERARIQPSLAPLAASAALMSNIATVLQLALVLGLFSPALLAWAVPALAGAGLGALAAAWLAARAVAPDAGTGEAAAERPYDPLSALRLSALLAGVLIAASLARAWLGAESLPWVLTLAGLADVHAAAAAAAQTVAQGGPAGPAQYGLLGAFAVNGAVKCLVAVTRGSRDYAWRVAVGVAAMQVAFVLGAVLASH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLB0</accession>
    <name>A0A0S2DLB0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">LemA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_3926</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LemA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948652.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3926"/>
    <dbReference type="EnsemblBacteria" id="ALN59268">
        <property type="protein sequence ID" value="ALN59268"/>
        <property type="gene ID" value="GLE_3926"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3926"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3863"/>
    <dbReference type="OMA" id="VETQYQR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023353">
        <property type="entry name" value="LemA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007156">
        <property type="entry name" value="MamQ_LemA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34478">
        <property type="entry name" value="PTHR34478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04011">
        <property type="entry name" value="LemA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140478">
        <property type="entry name" value="SSF140478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594925" evidence="7">
        <location>
            <begin position="21"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="180"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="192"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="218" mass="23832" checksum="EBF2991E233E320E" modified="2016-02-17" version="1">MFRPLIVLALAVLLSGCGYNTIQQKDESVTAAWSQVLNVYKRRADLVPNLVATVKGYASHEQQVLTQVTEARAKVGSINVNADDPGSLQQFEQAQGELRGAIGRLLVVSENYPQLKADQSFLSLQTQLEGTENRIAVERQRYIASVQDYNTYIRQFPTNLTAKMFGYATKPNFTVENEAQIQQAPTVDFGAAPPAAQPPAPQQPASQPPASQPPAPQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLC1</accession>
    <name>A0A0S2DLC1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phage-tail_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_19820</name>
        <name evidence="2" type="ORF">GLE_4039</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948733.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4039"/>
    <dbReference type="EnsemblBacteria" id="ALN59381">
        <property type="protein sequence ID" value="ALN59381"/>
        <property type="gene ID" value="GLE_4039"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4039"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3981"/>
    <dbReference type="OMA" id="IATEEWA"/>
    <dbReference type="OrthoDB" id="840724at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032876">
        <property type="entry name" value="J_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13550">
        <property type="entry name" value="Phage-tail_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage-tail_3" evidence="1">
        <location>
            <begin position="127"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="663" mass="71090" checksum="957CEE8FBD006FD0" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLJ8</accession>
    <name>A0A0S2DLJ8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein TolA-like</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_19900</name>
        <name evidence="3" type="ORF">GLE_4053</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948745.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4053"/>
    <dbReference type="EnsemblBacteria" id="ALN59395">
        <property type="protein sequence ID" value="ALN59395"/>
        <property type="gene ID" value="GLE_4053"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4053"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3996"/>
    <dbReference type="OrthoDB" id="1818842at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242190" evidence="2">
        <location>
            <begin position="26"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="154" mass="16929" checksum="693EDE7EC8E5F886" modified="2016-02-17" version="1">MRAAARSLARIAAVAAGLAAMPALAAEIGRACDTPEHCLPQNQLRYYEVLRQAIGQHWQAPASAAADSACTLELTQSPGGKLVSVRTIQPCDLDPGGRDSLLAAARAASPLPYQGYQQVFRPVLRLSLRVAEPDDPKEREESRLKRWWQRMRDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLN8</accession>
    <name>A0A0S2DLN8_LYSEN</name>
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        <submittedName>
            <fullName evidence="3">General secretion pathway protein M</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4174</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4174"/>
    <dbReference type="EnsemblBacteria" id="ALN59516">
        <property type="protein sequence ID" value="ALN59516"/>
        <property type="gene ID" value="GLE_4174"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4174"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4116"/>
    <dbReference type="OMA" id="NRSCAIS"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034756">
        <property type="entry name" value="T2SSM_b"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10741">
        <property type="entry name" value="T2SSM_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="231" mass="24849" checksum="026C6F8E0DF56702" modified="2016-02-17" version="1">MALNATGSRLRQLTADRERWLALGLLVAALGIAYAVLIHPWWTVPMMEADDTLHGLQERELRQRMELQQAPQVAQLLQRVRQQQSSRPGFLPEATAELATAGLVQRLETVVQQASPGNRSCGIVNRSPLAEPRRDRYARVVVQVRLRCGAPETAAVLHSLESGSPRLFVGNLNLLSTRGYFVPGSAGPANDGGLDVSFDLYGYLRPNPSAAPANARGGNNANAPAGAADAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLX1</accession>
    <name>A0A0S2DLX1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CRP-like protein Clp</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Catabolite activation-like protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLE_4266</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">C3</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4266"/>
    <dbReference type="EnsemblBacteria" id="ALN59607">
        <property type="protein sequence ID" value="ALN59607"/>
        <property type="gene ID" value="GLE_4266"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4266"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4204"/>
    <dbReference type="OMA" id="FLEYCHI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00325">
        <property type="entry name" value="Crp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00034">
        <property type="entry name" value="HTHCRP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="6" id="KW-0973">c-di-GMP</keyword>
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    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="7" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="10">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="HTH crp-type" evidence="11">
        <location>
            <begin position="114"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN59607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="186" mass="20750" checksum="3B7FFA855DFD8903" modified="2016-02-17" version="1">MFRPGDPASTLYYVVSGSVSIITEEEDGRELVLGYFGPGEFVGELGLFIESDHREVILRTRSTCELAEIGHERLYDLLLTRLSLDAPKLLYAIGAQISRRLLDTSRKAGRLAFLDVTDRIVRALHDLAKEPEAMSHPQGTQLRVSRQELSRLVGCSREMAGRVLKKLQADGKLHARGKTVVLYGTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLZ5</accession>
    <name>A0A0S2DLZ5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aminodeoxychorismate/anthranilate synthase component II</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Anthranilate synthase component II</fullName>
            <ecNumber evidence="2">4.1.3.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">trpG</name>
        <name evidence="3" type="ORF">FE772_20920</name>
        <name evidence="2" type="ORF">GLE_4273</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.1.3.27" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948921.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4273"/>
    <dbReference type="EnsemblBacteria" id="ALN59614">
        <property type="protein sequence ID" value="ALN59614"/>
        <property type="gene ID" value="GLE_4273"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4273"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4211"/>
    <dbReference type="OMA" id="TEHGHAM"/>
    <dbReference type="OrthoDB" id="1561172at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004049">
        <property type="term" value="F:anthranilate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00566">
        <property type="entry name" value="trpG_papA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GATase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="193" mass="21524" checksum="CD504E1F408C4B60" modified="2016-02-17" version="1">MSVLMIDNYDSFTYNLVQYLQALGSEVEVIRNDELTVDEIERRAPQRIVISPGPCTPDQAGVSLEVIRRLGAHTPILGVCLGHQSLGQAYGGQVIRAKRIMHGKTSAIRHQGAGVFAGLPDGYEATRYHSLVVERESLPDGLEVTAWTEYEDGGFEEIMGLRHREHPVEGVQFHPESIKTEHGHALLRNFLQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM07</accession>
    <name>A0A0S2DM07_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_21165</name>
        <name evidence="3" type="ORF">GLE_4330</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948966.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4330"/>
    <dbReference type="EnsemblBacteria" id="ALN59671">
        <property type="protein sequence ID" value="ALN59671"/>
        <property type="gene ID" value="GLE_4330"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4330"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4269"/>
    <dbReference type="OMA" id="IRARNAM"/>
    <dbReference type="OrthoDB" id="1729234at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242195" evidence="2">
        <location>
            <begin position="24"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="281" mass="30498" checksum="87CE82C9820066A4" modified="2016-02-17" version="1">MFRSFALLAAAALTAGACTPVQARPLVDVVVIDRDNGDWLPNWSWRGQQWIAGTPGHRYTVRLTNNTGERVLVVLSVDGVNAVSGQTASPAQSGYVLDAWQSTEINGWRKSLDDVAQFVFTDLGDSYAARTGRPANVGVIGAAVFQERQRYRPVYPTPSPYPYPPYARNENGAAKAEGRAAGNAAPAAPAERARESVAADTAAQAQTIGTGHGAREWSPVSQTEFVRASRSPAQVVELRYDDYATLVARGVVPRYPDRAYRPDTPRAFPEGFVADPPPRRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM54</accession>
    <name>A0A0S2DM54_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4155</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948831.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59497">
        <property type="protein sequence ID" value="ALN59497"/>
        <property type="gene ID" value="GLE_4155"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4155"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4097"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="147" mass="15911" checksum="627F2C8B186E276B" modified="2016-02-17" version="1">MSAAGRSERETPRVAIAFDAATGALHLGAMVVGADIAIDALPPGFEPGATQTVEVAGRSVSCRFAEADWRDDAPGERGRRVQLRLRFEDDVWVSAFCVLRGAGAAAHRHWLLRKFGAAEGVVVGCRWGVAEDRSGDCHAFVHNRNWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM55</accession>
    <name>A0A0S2DM55_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AMP-binding enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4441</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4441"/>
    <dbReference type="EnsemblBacteria" id="ALN59782">
        <property type="protein sequence ID" value="ALN59782"/>
        <property type="gene ID" value="GLE_4441"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4441"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4378"/>
    <dbReference type="OMA" id="ERAIMAW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="119"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="362"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="449" mass="47227" checksum="D6418C519A6B6F5E" modified="2016-02-17" version="1">MNAVERARRTGRDWTQALADSASVVHLGGESISAKDLLARGRAGWRAHAACSFPALRGIGDVDMLSLLLAAIVDRRPVLLCAADATPPAVCDGSIGAAAEARATDAPGERASATGERERCPDGLAVLSSGTLGTPKTIWHDPRDLLATAALVMRRLALGADDRVLVTVPLHHMYGLGAALIPALLAGAQVHLLPKANLLSFNDALRAAAPSWVYSTPHLLRTLVQRKQTAISPPCSLVLAGDGIPEPLRAQAQLVFQRVFDLYGSSELGVIAISGPNQPRALHPLDGVRAFAAEAGAAQTRLLVRHPHAATHIAQTDAPIALPQAWDTGDIAIFHHEGGFAIQGRADLSLNRAGKLLVLADLERAIMAWPGVDLAVAIALDEDSAAGKAIAVVIQPSSPALTVDALKRHAADTLPVFARPDRYALAAELPRLSSGKPDRNTITKDYRHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM67</accession>
    <name>A0A0S2DM67_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">7-carboxy-7-deazaguanine synthase</fullName>
            <shortName evidence="5">CDG synthase</shortName>
            <ecNumber evidence="5">4.3.99.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Queuosine biosynthesis protein QueE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">queE</name>
        <name evidence="7" type="ORF">GLE_4049</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>6-carboxy-5,6,7,8-tetrahydropterin + H(+) = 7-carboxy-7-deazaguanine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:27974"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:61032"/>
            <dbReference type="ChEBI" id="CHEBI:61036"/>
            <dbReference type="EC" id="4.3.99.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </cofactor>
        <text evidence="5">Binds 1 S-adenosyl-L-methionine per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.3.99.3" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948742.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4049"/>
    <dbReference type="EnsemblBacteria" id="ALN59391">
        <property type="protein sequence ID" value="ALN59391"/>
        <property type="gene ID" value="GLE_4049"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4049"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3992"/>
    <dbReference type="OMA" id="CDTEYAF"/>
    <dbReference type="OrthoDB" id="1141206at2"/>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016840">
        <property type="term" value="F:carbon-nitrogen lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00917">
        <property type="entry name" value="QueE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024924">
        <property type="entry name" value="7-CO-7-deazaguanine_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027621">
        <property type="entry name" value="rSAM_QueE_gams"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000370">
        <property type="entry name" value="QueE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04349">
        <property type="entry name" value="rSAM_QueE_gams"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="6">
        <location>
            <begin position="33"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="27"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="5">
        <location>
            <begin position="52"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="227" mass="25395" checksum="9467DE356F67E6ED" modified="2016-02-17" version="1">MNAAVVSETAAAPSSERLRLTEIFLSLQGESDSIGWPTVFVRLTGCPLRCQYCDTAYAFHGGEWWTYESILAEVASHGARHVCVTGGEPLAQKRCIELLKRLCDAGYEVSLETSGAIDIGPVDPRVSRVLDIKTPDSKEAHRNLWSNLALLSARDQIKFVICSREDYEWSKAIVAEHGLTAVCAVMFSPSFHQIRPRDLADWIVADRLPVRFQLQLHKILWDDEPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMB1</accession>
    <name>A0A0S2DMB1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_23190</name>
        <name evidence="3" type="ORF">GLE_4339</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000079">
        <property type="protein sequence ID" value="OPD61527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948975.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000079.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59680">
        <property type="protein sequence ID" value="ALN59680"/>
        <property type="gene ID" value="GLE_4339"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61527">
        <property type="protein sequence ID" value="OPD61527"/>
        <property type="gene ID" value="BV903_23190"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4339"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4278"/>
    <dbReference type="OrthoDB" id="2061422at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595377" evidence="2">
        <location>
            <begin position="23"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD61527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="93" mass="9720" checksum="180DA7BC38E5895E" modified="2016-02-17" version="1">MLRICLCLLFLSASLAVAQASAREVNKLSPNDACSSGGAAKDAPARAQARGGNGGAPQTARDTKAKPSVHSDSDAGNRLQSPRWHNFLPGMFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMK5</accession>
    <name>A0A0S2DMK5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4654</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949214.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4654"/>
    <dbReference type="EnsemblBacteria" id="ALN59995">
        <property type="protein sequence ID" value="ALN59995"/>
        <property type="gene ID" value="GLE_4654"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4654"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4590"/>
    <dbReference type="OMA" id="PGLVMGF"/>
    <dbReference type="OrthoDB" id="1320028at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="2">
        <location>
            <begin position="22"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="500" mass="53966" checksum="88BF1F5BA45446C8" modified="2016-02-17" version="1">MAKHAGSVFSVDVTGLEPEAGQPAYARIGERIRAAILSGALPPEARLPSARTLAHDLGVARNTVDWALDQLVADGYIVRRRGAGSFVAARLPERDAPPLRPDSSRVALPDTAPRRLSRRAEALRAYPGHYAPAAATPFTPSLPPTDLFPRQTWNRLLQREAARSGDDYWHYGASNGLPALRRAIAAHASAMRAVRCSAEQVIVVTSTQQAVELAAKALADPGDRAWCESPGYPPARHGLRSAGLDIVDVRIDDEGLDVAAGLVAAPDARLAYLTPAHQYPLGVELSLSRRRALLDWAHERDAYVLEDDYDGDYRYEGRPIASLQAMDERGRVVYIGSFNKILFPALRIAYAIVPEPLIDAFVDAKHIADGHTALLMQGVLAAFIEEGHLGRHLRKTRAAHDQRRLAFLEHAQVLRPWLDFGPAVAGMHVAARFTDAAAGLDDRAVSAACAEAGIVVHPLSKYGESGRGGLVFGFASALPHRVQGGCEVVRKVLAGCRSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMT1</accession>
    <name>A0A0S2DMT1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_22060</name>
        <name evidence="1" type="ORF">GLE_4517</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949115.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4517"/>
    <dbReference type="EnsemblBacteria" id="ALN59858">
        <property type="protein sequence ID" value="ALN59858"/>
        <property type="gene ID" value="GLE_4517"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4517"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4453"/>
    <dbReference type="OMA" id="NCYGGCK"/>
    <dbReference type="OrthoDB" id="1596827at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="243" mass="26303" checksum="A9BD6F00429C7972" modified="2016-02-17" version="1">MNVRQATALLAAAMILAGCDKPDPKAAEAALAAQKEQAAAAEAKNFDSAYAEQKWDMAAAYGEIVTSKYAGTPTAERIRAQYEEAQGKAKTAREQRRVESLWSYMSTPVKLAKGKDGTQLSASIYAKANVETDGSTPRPVQLIFRDHPDWGRSSYLVLQVGDFNCYGGCKLKVGVDGKVKTMAGSRPKTDEAIAMFVEDERALWRMLGGAKELSIEFPVKAGGTRTATFEVGGLKPEKMPGWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN35</accession>
    <name>A0A0S2DN35_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4798</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60139">
        <property type="protein sequence ID" value="ALN60139"/>
        <property type="gene ID" value="GLE_4798"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4798"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="65" mass="7138" checksum="AA3E988E332A75AE" modified="2016-02-17" version="1">MREPAAPSRLYTTLAAPAPCLRGLFVHARAWPLRLVAIRFDRVGPHPRHGATTAPNQRCAARLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN40</accession>
    <name>A0A0S2DN40_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4713</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949256.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60054">
        <property type="protein sequence ID" value="ALN60054"/>
        <property type="gene ID" value="GLE_4713"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4713"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4647"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007497">
        <property type="entry name" value="DUF541"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04402">
        <property type="entry name" value="SIMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595420" evidence="1">
        <location>
            <begin position="22"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="229" mass="25183" checksum="50262CD2A4396216" modified="2016-02-17" version="1">MNMAAAWILALGLAWPAAAAAQDIETGGRLRVAGFGRVAWQPDLYELAFAAVGDGADANAARERFEPAHAALRRVLDAHAGALAGRAQDPPRLQSRGTQAAPQWRFSSRFAVRVRGEAALVRLQQALAEAGVAEFELRPFSERLPEYTEQAQRLALRDAQRRALAIAQELGWRLRGARAVKFLDERPWWSPQTPTARQYGARAYDYAAEAPAQTGEVTAQAEVEFEYSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DND8</accession>
    <name>A0A0S2DND8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">R body protein RebB-like protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">RebB protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rebB</name>
        <name evidence="2" type="ORF">BV903_15755</name>
        <name evidence="4" type="ORF">D9T17_06030</name>
        <name evidence="3" type="ORF">FE772_22725</name>
        <name evidence="1" type="ORF">GLE_4664</name>
    </gene>
    <organism evidence="1 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 5">C3</strain>
        </source>
    </reference>
    <reference evidence="2 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">OH11</strain>
        </source>
    </reference>
    <reference evidence="3 8" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000041">
        <property type="protein sequence ID" value="OPD62930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000019">
        <property type="protein sequence ID" value="ROU07765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949221.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60005">
        <property type="protein sequence ID" value="ALN60005"/>
        <property type="gene ID" value="GLE_4664"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62930">
        <property type="protein sequence ID" value="OPD62930"/>
        <property type="gene ID" value="BV903_15755"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4664"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4600"/>
    <dbReference type="OMA" id="TDACDCK"/>
    <dbReference type="OrthoDB" id="2059941at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021070">
        <property type="entry name" value="Killing_trait_RebB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11747">
        <property type="entry name" value="RebB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD62930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROU07765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="106" mass="10995" checksum="D1AA03CE417AB33C" modified="2016-02-17" version="1">MAFPTAVNDQITDAVTQSNVKVIGEAPAFAMGSIYQSMAHSTGILFENAVAAQQQQNSLSQAAANQGVMQIYSVDTTAAAGATEKVAQTGVSDNLTSLLTVLRAFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNF8</accession>
    <name>A0A0S2DNF8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aldehyde-activating protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">GFA family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Glutathione-dependent formaldehyde-activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">BV903_10475</name>
        <name evidence="6" type="ORF">FE772_23445</name>
        <name evidence="4" type="ORF">GLE_4825</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">C3</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Gfa family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000023">
        <property type="protein sequence ID" value="OPD64006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949341.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4825"/>
    <dbReference type="EnsemblBacteria" id="ALN60166">
        <property type="protein sequence ID" value="ALN60166"/>
        <property type="gene ID" value="GLE_4825"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64006">
        <property type="protein sequence ID" value="OPD64006"/>
        <property type="gene ID" value="BV903_10475"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4825"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4756"/>
    <dbReference type="OMA" id="RRTRFWP"/>
    <dbReference type="OrthoDB" id="1474484at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016846">
        <property type="term" value="F:carbon-sulfur lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006913">
        <property type="entry name" value="CENP-V/GFA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04828">
        <property type="entry name" value="GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51891">
        <property type="entry name" value="CENP_V_GFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CENP-V/GFA" evidence="3">
        <location>
            <begin position="11"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD64006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW28164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="139" mass="15279" checksum="18ACC356D4FBF34C" modified="2016-02-17" version="1">MSEHTPDSGTFHGGCHCGAVRFRAQVDPAQGSVRCNCSLCARMRRWAAILAPSAFELLEGEDALADYRFGRGVARHRFCRHCGVHVFAQNHVEELGGDYVSLSLACLDVAPQWLAAVPVAYLNGRDEDWERPPAVTAHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNN9</accession>
    <name>A0A0S2DNN9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4375 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_21550</name>
        <name evidence="2" type="ORF">GLE_4411</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949034.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59752">
        <property type="protein sequence ID" value="ALN59752"/>
        <property type="gene ID" value="GLE_4411"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4411"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4350"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025402">
        <property type="entry name" value="DUF4375"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14300">
        <property type="entry name" value="DUF4375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4375" evidence="1">
        <location>
            <begin position="32"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="236" mass="25681" checksum="B01C9E140C2391A8" modified="2016-02-17" version="1">MAGIGALTSFKFVHAIYTYGLTPKAEREGRAALTIPERVVLLAWWARGVIVEGGFAQLYASSADPDEVADAFKAVGAEAAWQACLDAKAVFPDGPPPGKPDERAERMKPLASGDEAGALWDAQDRAVRSLGEAFDDWVAAYVREHQESFVRSLVSPWVTFFHGAGSAGLFEVPGPDRPGVYPYEANRGPAHYEMGLALESEGSAWCWLRQKDGTRLRFRVVGRHDGGLVLEDFSPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNP5</accession>
    <name>A0A0S2DNP5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Multidrug efflux SMR transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Multidrug resistance protein, SMR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FE772_23215</name>
        <name evidence="6" type="ORF">GLE_4771</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949302.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60112">
        <property type="protein sequence ID" value="ALN60112"/>
        <property type="gene ID" value="GLE_4771"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4771"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4705"/>
    <dbReference type="OMA" id="EVFWVIG"/>
    <dbReference type="OrthoDB" id="1990300at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042221">
        <property type="term" value="P:response to chemical"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000390">
        <property type="entry name" value="Small_drug/metabolite_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045324">
        <property type="entry name" value="Small_multidrug_res"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30561">
        <property type="entry name" value="PTHR30561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00893">
        <property type="entry name" value="Multi_Drug_Res"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN60112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW28125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="109" mass="10961" checksum="65C6744C786368A0" modified="2016-02-17" version="1">MSAGTAWIMLIAAGLIDVAWALSMKLSNGYTRPGWTAVSLIALAAFVWLLGRALTALPVGVAYAVWTGIGAAGTVLIGSVLFGEAITPLKLGGVGLIVGGIVLLRSAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNR0</accession>
    <name>A0A0S2DNR0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4954</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60295">
        <property type="protein sequence ID" value="ALN60295"/>
        <property type="gene ID" value="GLE_4954"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4954"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4881"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="76" mass="8688" checksum="0B84DE7DCDE32531" modified="2016-02-17" version="1">MRCRGRGSRRSYSRIRNPTSVIPAKAGTHFDFAAALTVTEVSRDDKPPSRAFARKRSSYFLLSARQKKVAKEKRLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNR5</accession>
    <name>A0A0S2DNR5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_23705</name>
        <name evidence="1" type="ORF">GLE_4881</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949386.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60222">
        <property type="protein sequence ID" value="ALN60222"/>
        <property type="gene ID" value="GLE_4881"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4881"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4812"/>
    <dbReference type="OrthoDB" id="1536122at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="151" mass="16899" checksum="37B9FF96D0A51882" modified="2016-02-17" version="1">MLQRRLQHDRTGCGLACVAMLAGIGYAQARTLARALAIGPRPYRYRAGGGLRTAREGWLTDARQLRRMLAVLRIGSGGERAVSAWRDCDGDGLVAINARADGTWHWVVYLHDPVSPRVLDPNPRVRRGERRDFGRMRPVRFVPVTLHEASM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNT1</accession>
    <name>A0A0S2DNT1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aminotransferase, classes I and II superfamily</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">PLP-dependent aminotransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_23435</name>
        <name evidence="4" type="ORF">GLE_4824</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949340.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4824"/>
    <dbReference type="EnsemblBacteria" id="ALN60165">
        <property type="protein sequence ID" value="ALN60165"/>
        <property type="gene ID" value="GLE_4824"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4824"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4755"/>
    <dbReference type="OMA" id="MRLNFTY"/>
    <dbReference type="OrthoDB" id="1024978at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW28162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="472" mass="51245" checksum="BA73C98756327DEB" modified="2016-02-17" version="1">MTRYQSLADDIARSIRQGLLRPGQRLPSVRQASAARKLSPATVFQAYYLLEAQGLVRSRPRSGYYVAPAAQRLPPEPDTASAPRGESRPVDVSALVFDVLESAMAREIVPLGSAFMSPALFPLARLGRAMAHEAVHLDPRSTVDDLTPGNAELRRHIALRYRVEGVELGAGDLVVCNGAIEALNLCIAATTRPGDAVLVESPCFYAALQTLERHGLRAVEVPTHPREGIELGALEAAIRRHAPKACWAMTRFQNPLGASLPEAKTRELVQLLARHDLPLIEDDVYGELHFGARAAPPAKAFDTRGLVLHCSSFSKTLAPGYRIGWAAPGRYTQQVARLKLTNTLATCVPAQLAIARYLQRGGYERHLRGLRKTLAQQQAAYLDAVARHFPAGTRVTRPDGGYFLWIELPPGRDALALQRQAAQRGISIAPGPMFSAERGYGRCLRLNYGHPLDARIEDALATLGALSAAPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNU0</accession>
    <name>A0A0S2DNU0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase, group 2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4969</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4969"/>
    <dbReference type="EnsemblBacteria" id="ALN60310">
        <property type="protein sequence ID" value="ALN60310"/>
        <property type="gene ID" value="GLE_4969"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4969"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4896"/>
    <dbReference type="OMA" id="TEYSMSK"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="31"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="291" mass="31720" checksum="2C4A477FA7D71AA6" modified="2016-02-17" version="1">MTDTSSRTRVPVLAPAPRTERARLHRDNVAVVIPALNEALRIREVVEGALAQCALVIVIDDGSDDGTGERIADLPAVLLRHPQRQGKGASLRDGFAEALRRGAAAVLTMDGDGQHAAADIARLIDSGNRHPGHIVIGARLRKRAAQPTYRRLANNFGDWGVAWGTGYQVADSQSGQRLYPAEVAALERVPGEDFVFEAQILMSAAQRLGTRCVSVPIESRYNADGEQAYRASHFKPLRDFSRITSHIVLQCLRRGRVPEVYRSIRANPPLIDDPSGEFASAPRREASTGPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNY9</accession>
    <name>A0A0S2DNY9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">LysR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR-family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_23825</name>
        <name evidence="3" type="ORF">GLE_4909</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949408.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4909"/>
    <dbReference type="EnsemblBacteria" id="ALN60250">
        <property type="protein sequence ID" value="ALN60250"/>
        <property type="gene ID" value="GLE_4909"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4909"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4839"/>
    <dbReference type="OMA" id="EDTTCTD"/>
    <dbReference type="OrthoDB" id="860559at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="284" mass="29968" checksum="D5CB6C4CB1C681D5" modified="2016-02-17" version="1">MRSLDLDQLRAFVAVAEAGSISAGAGRVFRSQSAVSEQLQKLESAAGAALLLRSRQGVGLTAAGQRLIGHARQLLALGELALHDVRNEVRRTQARLAISDYFRSDEIAGLLAQLGRRCPQLRLQVEVGLSAALAQGHAEGRHDLAVIMRTGAARERATTLPLRREALHWVAAPGLDLREESELPLVLLPPDCRLHGLAVQRLRAHRSAHRIAHQASGVAGLQAALRAGLGVGCLNASAIGPGLAIARSPRLPALPDCAFALLAPPADAPADLHEAAAIVRAFFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP05</accession>
    <name>A0A0S2DP05_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acriflavin resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_4838</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949350.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60179">
        <property type="protein sequence ID" value="ALN60179"/>
        <property type="gene ID" value="GLE_4838"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4838"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4768"/>
    <dbReference type="OMA" id="WVQTPEY"/>
    <dbReference type="OrthoDB" id="145346at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="336"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="437"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="466"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="533"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="885"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="911"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="942"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="986"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1017"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1049"/>
            <end position="1072"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="1072" mass="113697" checksum="B1574C50C0935914" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPC7</accession>
    <name>A0A0S2DPC7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5089</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60430">
        <property type="protein sequence ID" value="ALN60430"/>
        <property type="gene ID" value="GLE_5089"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5089"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="68" mass="7821" checksum="8ABAA9859A033AC9" modified="2016-02-17" version="1">MRHERLAPVEWIPWECAAKDDGSVENLSERRCARRARRLRADIANDAPRVRDRAKCRSPRGARRGVPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPI3</accession>
    <name>A0A0S2DPI3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucokinase</fullName>
            <ecNumber evidence="2">2.7.1.2</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="4">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">glk</name>
        <name evidence="3" type="ORF">BV903_11310</name>
        <name evidence="4" type="ORF">FE772_24990</name>
        <name evidence="2" type="ORF">GLE_5159</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial glucokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.2" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000026">
        <property type="protein sequence ID" value="OPD63884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949596.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5159"/>
    <dbReference type="EnsemblBacteria" id="ALN60500">
        <property type="protein sequence ID" value="ALN60500"/>
        <property type="gene ID" value="GLE_5159"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63884">
        <property type="protein sequence ID" value="OPD63884"/>
        <property type="gene ID" value="BV903_11310"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5159"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5082"/>
    <dbReference type="OMA" id="QAFCGFM"/>
    <dbReference type="OrthoDB" id="992687at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004340">
        <property type="term" value="F:glucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005536">
        <property type="term" value="F:glucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003836">
        <property type="entry name" value="Glucokinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02685">
        <property type="entry name" value="Glucokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD63884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="350" mass="36468" checksum="6F5E9251C00CD4DE" modified="2016-02-17" version="1">MSAAPRLTPAASAEAGSFIAADVGGTHTRVGLVRPGQGGDTVAVLAHRKYVCADYPSLAPILSAFLAEFTAGNGIGVERVVIACAGVVLEDRVVNSNLPWPISLSELRAELGLREVLFINDFQANANAAQCMAPDDSTLLTPGVRDAAPGPVLVIGPGTGLGAAIRIPHGRGTVVLPTEAGHTAFAPGNAREVEMLRLVQQRGHDYVKTEHFVSGPGLVNLYDSLCTLAGVEPALRAPAAITEAARRGDAIAREAVLTFCALLGSVIGDLVVISGAKSVFIAGGILPQLKDFVPDSPFHARMLDKGVMRPVLETVPVRLIENERLGVIGAASWYLEHARDAHGDAARPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPR4</accession>
    <name>A0A0S2DPR4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_24915</name>
        <name evidence="3" type="ORF">GLE_5140</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5140"/>
    <dbReference type="EnsemblBacteria" id="ALN60481">
        <property type="protein sequence ID" value="ALN60481"/>
        <property type="gene ID" value="GLE_5140"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5140"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5065"/>
    <dbReference type="OMA" id="KFAYAAS"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010239">
        <property type="entry name" value="CHP02001"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09694">
        <property type="entry name" value="Gcw_chp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02001">
        <property type="entry name" value="gcw_chp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="279" mass="29699" checksum="06EA6C528FAF4F43" modified="2016-02-17" version="1">MSSHTSETTTDAVAITASRVRTTPAHAPNQKHASRRALLALALACAAAPAFAGTSGSIALTTDYLFRGVSQTNQKPALQAGVEYAHDSGFYVGAWGSNVSWLSDTVVVGDDISSSLELDGYLGYRGKAGEIFSYDVGVLTYYYPGSYPSGFNSPNTTEVYLGGTLAPSETVSIGLKYSYSVTDLFGYADSDGSGYLDASLNWTFQPGWALNLHGGKQWIEGNKAFEYTDWKLAVTKSFDNGFSVAAAYSDTDAEKALYTNAHGNFLADSAFTLTLSKAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPZ6</accession>
    <name>A0A0S2DPZ6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transport energizing protein, ExbD/TolR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_5329</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5329"/>
    <dbReference type="EnsemblBacteria" id="ALN60670">
        <property type="protein sequence ID" value="ALN60670"/>
        <property type="gene ID" value="GLE_5329"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5329"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5246"/>
    <dbReference type="OMA" id="ATKSDHG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30558">
        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN60670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="117" mass="13268" checksum="E830887C83B50CCF" modified="2016-02-17" version="1">MDVMLVLLIIFMITAPLMTHKVEIKLPEATLKKVEEAPKTPPITLSIQEDGHIYWNDEPITADQLESRLSVEAQKTPQPSINVRGDRTTKYRTINNVVTIAQKQGMRKVGFVAIKER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ89</accession>
    <name>A0A0S2DQ89_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5304</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5304"/>
    <dbReference type="EnsemblBacteria" id="ALN60645">
        <property type="protein sequence ID" value="ALN60645"/>
        <property type="gene ID" value="GLE_5304"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5304"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5222"/>
    <dbReference type="OMA" id="TCGIFAC"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008579">
        <property type="entry name" value="UGlyAH_Cupin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05899">
        <property type="entry name" value="Cupin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_3" evidence="1">
        <location>
            <begin position="61"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="138" mass="15052" checksum="CAC3C22369F7998F" modified="2016-02-17" version="1">MERPALTFFFTSRGNRNMSMTPIERGLSIEALDPWGTVADLGSQPLEGEVRAYGRMTYGAPTDALSAGYFGATRGKFRLVYPFAEHAVVVAGEVALTDESTGTTTRYRAGDGWFVAKGTSTVWEILSDEFVKHYVAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQN0</accession>
    <name>A0A0S2DQN0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4007 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_00635</name>
        <name evidence="2" type="ORF">GLE_5485</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949840.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5485"/>
    <dbReference type="EnsemblBacteria" id="ALN60826">
        <property type="protein sequence ID" value="ALN60826"/>
        <property type="gene ID" value="GLE_5485"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5485"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5400"/>
    <dbReference type="OMA" id="RQMWLKK"/>
    <dbReference type="OrthoDB" id="1476027at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025248">
        <property type="entry name" value="DUF4007"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13182">
        <property type="entry name" value="DUF4007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4007" evidence="1">
        <location>
            <begin position="18"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="309" mass="35128" checksum="015617C0C489798C" modified="2016-02-17" version="1">MLEDFAPASVERASGERFSGHESFACRYGWLPKFYDLLVRRPDLIRHDEEVMVALGIGRNMVKSVRFWAQAFGLMDDSPRMPPAPTVFAQWLLDPQRGEDPYLEDVGSLWLLHWRLAATANLAAWEVAFFEIPEREILRRFLLQRVERHAVELEKKLSATTIRQHVDIFLSCYATPLVTQGQTVEESLGCPLQELGLVRLSPAGDRDELIEFARGPWRHLSPITFLRILLDYWQLRAPHDKTIAVRALLTDFGSPGLTLRLDEGSLWQLLQATEKVSGGIVQLTDSIERRAVVLQAADVQRAKAAIKYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DRD3</accession>
    <name>A0A0S2DRD3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5522</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60863">
        <property type="protein sequence ID" value="ALN60863"/>
        <property type="gene ID" value="GLE_5522"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5522"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5437"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="199" mass="22770" checksum="1F59498B836DDBD4" modified="2016-02-17" version="1">MRFARGEAFMSTPQRRGDDKESEMGPLVTKSNADLRALGNRIERLLMSTVSAFEAEVKMKLYGCYGLSHLLASHCMGHQTGRCDPEVISWMAEGCGYELDPLELAIEESDEWFKRRLMPSEFSANELTLRALLTHIHRYLEGDEPEYSALPVAELDRLMQRVRLLEVWELRDAGYQKALCAALKNLQRARDAAEYEPRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA16</accession>
    <name>A0A0S2DA16_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0019</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55378">
        <property type="protein sequence ID" value="ALN55378"/>
        <property type="gene ID" value="GLE_0019"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0019"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.26"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="38" mass="4262" checksum="676E44C02E6D9F2D" modified="2016-02-17" version="1">MLPRYEAMIELFKEETANDEVGHLLSADQIARLLTATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAR6</accession>
    <name>A0A0S2DAR6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Biosynthetic arginine decarboxylase</fullName>
            <shortName evidence="11">ADC</shortName>
            <ecNumber evidence="11">4.1.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11 16" type="primary">speA</name>
        <name evidence="17" type="ORF">FE772_02050</name>
        <name evidence="16" type="ORF">GLE_0244</name>
    </gene>
    <organism evidence="16 18">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="16 18" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">C3</strain>
        </source>
    </reference>
    <reference evidence="17 19" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 11">Catalyzes the biosynthesis of agmatine from arginine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>H(+) + L-arginine = agmatine + CO2</text>
            <dbReference type="Rhea" id="RHEA:17641"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:58145"/>
            <dbReference type="EC" id="4.1.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11 12">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="11">Amine and polyamine biosynthesis; agmatine biosynthesis; agmatine from L-arginine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.19" evidence="11"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945897.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0244"/>
    <dbReference type="EnsemblBacteria" id="ALN55603">
        <property type="protein sequence ID" value="ALN55603"/>
        <property type="gene ID" value="GLE_0244"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0244"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.246"/>
    <dbReference type="OMA" id="AVEYTQH"/>
    <dbReference type="OrthoDB" id="164471at2"/>
    <dbReference type="UniPathway" id="UPA00186">
        <property type="reaction ID" value="UER00284"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008792">
        <property type="term" value="F:arginine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006527">
        <property type="term" value="P:arginine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06830">
        <property type="entry name" value="PLPDE_III_ADC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01417">
        <property type="entry name" value="SpeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040634">
        <property type="entry name" value="Arg_decarb_HB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041128">
        <property type="entry name" value="Arg_decarbox_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002985">
        <property type="entry name" value="Arg_decrbxlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022657">
        <property type="entry name" value="De-COase2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43295">
        <property type="entry name" value="PTHR43295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17810">
        <property type="entry name" value="Arg_decarb_HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17944">
        <property type="entry name" value="Arg_decarbox_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001336">
        <property type="entry name" value="Arg_decrbxlase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01180">
        <property type="entry name" value="ARGDCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01273">
        <property type="entry name" value="speA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00879">
        <property type="entry name" value="ODR_DC_2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="10 11 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 11" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="11 12" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0745">Spermidine biosynthesis</keyword>
    <feature type="domain" description="Orn_Arg_deC_N" evidence="13">
        <location>
            <begin position="81"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="Arg_decarb_HB" evidence="14">
        <location>
            <begin position="365"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="Arg_decarbox_C" evidence="15">
        <location>
            <begin position="576"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="11 12">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001336-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF17810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF17944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ALN55603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="QCW24639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="629" mass="69261" checksum="040806AF1344A045" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAU4</accession>
    <name>A0A0S2DAU4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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        </lineage>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="64" mass="7099" checksum="D73509CB21BEE6E8" modified="2016-02-17" version="1">MRPIVLVAGRLHRKPASTRGSPAPARTDCRNENAAAHRGVLVFGDAGSRRSPRRRLSRRGRSWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB26</accession>
    <name>A0A0S2DB26_LYSEN</name>
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            <fullName evidence="1">Protein Smg homolog</fullName>
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        <lineage>
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            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
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    <comment type="similarity">
        <text evidence="1">Belongs to the Smg family.</text>
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    </dbReference>
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    <dbReference type="KEGG" id="lez:GLE_0352"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DUF494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="169" mass="19501" checksum="D42C233BFF5A59E9" modified="2016-02-17" version="1">MRRRPREMKESILDVLLYLFEHYFTDDADLVRDRDSLRSGPLFEELGQAGFSPAEINKAIEWLDALAQQRPSVSRPSAGGPTRIYFGPELDKLDVECRGFLLFLEQHGILDADQRELVLDRAMALDQDELDLDDLKWVVLMVLFNQPGSEAAYAWMETQMFEDEPEPVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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        <property type="gene ID" value="GLE_0422"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
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        <location>
            <begin position="24"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="185" mass="19219" checksum="67DBEC09FEE0DB53" modified="2016-02-17" version="1">MKIQFLPLCAGLLAMSAMPAALAQSYTKQAELDLAATGETFSIGQTQYRIAPAAEVKRADAATDPRRDVIVGEYVVEPKAAAANARSKRAVDAVAGNGLGAAVSANGRAVVVAPELNVYFSNASVVDALVRETGGTLLYSSAAGGKATIGYASLAEAMKARQRILGKAGVKEVSPRLVQQRRVAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBF6</accession>
    <name>A0A0S2DBF6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LysM domain</fullName>
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    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0504</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="69.GLE_0504"/>
    <dbReference type="EnsemblBacteria" id="ALN55862">
        <property type="protein sequence ID" value="ALN55862"/>
        <property type="gene ID" value="GLE_0504"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0504"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.499"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="36"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="201" mass="21440" checksum="CF6102D8E102F801" modified="2016-02-17" version="1">MTTLNGPSYSGPQLGDLVNTKAEIENRQVAVPVGYKPVVVEPGDTLSEIAEANDIPLAQLLAANPQFSLDPASNPNTRSADLIYPGETVFVPSDEARTSDAAAAKYAQALDDSEQPSATHGEWETKSKAVTDAKVEFTQAVKAEIDASMTYSGNSREDFGKEAAAIGEKIAQRYENAGRPDLAQAAREAGQQRETEINNEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBH8</accession>
    <name>A0A0S2DBH8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyltransferase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0534</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55892">
        <property type="protein sequence ID" value="ALN55892"/>
        <property type="gene ID" value="GLE_0534"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0534"/>
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    <dbReference type="OMA" id="LAYEWRF"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="374"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl_transf_3" evidence="2">
        <location>
            <begin position="41"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="426" mass="45877" checksum="CDB0522FDB772F32" modified="2016-02-17" version="1">MVDIHTVWPYFAILLACLGLAALPAFRGADAAGGSGRRTDTLDGLRGFLALGVFAVHAVVHYDYLLSGVWKPSSARFYNVAAVISVALFFMLTGFLFWNKLLKAGGRPDWKALYIGRVFRLGPMYVAVVATMIAIVAYRTGFQWRQPPLQVIGQALAWLALGILPPPPAINGYADTGTILAGVTWTLLFEWLFYFSLPLWALFVRRGRHLAFSAGVVAACLLVILAGTWNGGFVPGVKPRPALLLAVLAELIATLATGMLVASLLHERIGERLRLHEARWGALALLAIALAFAAMLGARDVGMLQLLAFCPLLGTFLFVLCSGNDLFGALSWPASRRLSAMSYSIYLAQGLALVAVFAIPGVKAYALSGTLPFWIVNIGCALALCAASLLTYRYIEEPGIRAGKRLTERLRARRDAVAPLAVAADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBL5</accession>
    <name>A0A0S2DBL5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cupin domain protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Pirin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">BV903_15475</name>
        <name evidence="7" type="ORF">FE772_03550</name>
        <name evidence="5" type="ORF">GLE_0566</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the pirin family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000040">
        <property type="protein sequence ID" value="OPD63033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946130.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0566"/>
    <dbReference type="EnsemblBacteria" id="ALN55924">
        <property type="protein sequence ID" value="ALN55924"/>
        <property type="gene ID" value="GLE_0566"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63033">
        <property type="protein sequence ID" value="OPD63033"/>
        <property type="gene ID" value="BV903_15475"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0566"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.560"/>
    <dbReference type="OMA" id="NLRVWND"/>
    <dbReference type="OrthoDB" id="729805at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041602">
        <property type="entry name" value="Quercetinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43212">
        <property type="entry name" value="PTHR43212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17954">
        <property type="entry name" value="Pirin_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006232">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin" evidence="3">
        <location>
            <begin position="9"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin_C_2" evidence="4">
        <location>
            <begin position="150"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN55924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD63033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW24883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="233" mass="24982" checksum="D4E95236CE9B6EB8" modified="2016-02-17" version="1">MIELRPYSSLGGENHGWLDAKHHFSFAGYRDAARMGWGALRVWNDDTIAANTGFPPHSHADMEIITYVRDGAITHQDNLGNRGRTEAGDVQVMSAGSGIQHAEYNLEPGTTRIFQIWIIPDARGGAPTWGAKPFPKDDRGGRFVVLASGIEGDEDALPIRAAARVLGLTLAAGESAEYGFDGERYGYLVPAKGAIEVNGVTVNARDGAAIRGEARIRVTALEDAEVVLVDTAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBS7</accession>
    <name>A0A0S2DBS7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0604</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946155.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0604"/>
    <dbReference type="EnsemblBacteria" id="ALN55962">
        <property type="protein sequence ID" value="ALN55962"/>
        <property type="gene ID" value="GLE_0604"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0604"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.596"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594937" evidence="1">
        <location>
            <begin position="26"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="304" mass="30901" checksum="E4F6E297ED66B08F" modified="2016-02-17" version="1">MRKTSLRTAALAAALTLASASSANAGTPSGPYAMFKFCPYTNPSVGSCVLNTTTSGTLKIGSTTMPIDKPIVMQGGIESLGPSPFYAAVGAPTLQAPPGKVPGGLLGIVNPAPNWPGPLWTAFWAIVGAVNDVSATIEPVQAVQTNFGNALFPPEDGSDPTVARLAVRVHLQNPFLGGGCYIGSAQDPIVLKLQTGTTAPPPPNLPISGNTGNAYTVWTDEPNYIGYLQVDGNTLVDNSFAVPKAGGCGNIALGLPIITQVLDALVSGAVNLKVGLPAAAGTNTAIMNGKSSIASSQYVLNSEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBT3</accession>
    <name>A0A0S2DBT3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">DUF560 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">FE772_03780</name>
        <name evidence="10" type="ORF">GLE_0615</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the Slam family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0615"/>
    <dbReference type="EnsemblBacteria" id="ALN55973">
        <property type="protein sequence ID" value="ALN55973"/>
        <property type="gene ID" value="GLE_0615"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0615"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.607"/>
    <dbReference type="OMA" id="YAIEGHH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007655">
        <property type="entry name" value="Slam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04575">
        <property type="entry name" value="SlipAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242175" evidence="9">
        <location>
            <begin position="34"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN55973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW24920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="502" mass="56455" checksum="9A0258EA60A81D9E" modified="2016-02-17" version="1">MKPYRTVSNAIVPRAAGLAAGLALCLFSCAAPAQNSAQDRDDTRLRLDHGLEQRQAERERALLEEENAARGDAAALANVDLDDPNALAAALYQAVNARRWVQARPLLQRYRALPQRDRMLELYAQGALARADGDLRGAERDYRALLELQADFLPAQLELARVLFENQLDREAEQRFQAIAAALDAGDAKTAGVRRTVETFLRALRNRRGWHGSFALGPTWNDNLNQSSASRTCLLAAPDGQCAIERTLPAAIEGGGLDFDAGLTRRQPLRGHHGLYLRSLLYGYSYRDHSAYNETTASASIGYSYASARHAFTAAPQFEYSAFGNRSLYGAWGARADWSWTISPRWLFKLEGDHKRMRYRRNDLAGYDGPTSAVYATLWRALPRQWLLFGGLDLARRETRRDTEAYLQRGARLGLSKQFDAGASLLLFVSLRKRRHDEWNATFQARRRDDEFNATAIVRLPRLAFAGFTPSLTFKRNRTASSIDWLYGYDRDSVSLKLERAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBT9</accession>
    <name>A0A0S2DBT9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">D-amino acid dehydrogenase small subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dadA</name>
        <name evidence="2" type="ORF">GLE_0653</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0653"/>
    <dbReference type="EnsemblBacteria" id="ALN56011">
        <property type="protein sequence ID" value="ALN56011"/>
        <property type="gene ID" value="GLE_0653"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0653"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.642"/>
    <dbReference type="OMA" id="FWYKEDG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="1"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="409" mass="44541" checksum="A5C0D68D14979F59" modified="2016-02-17" version="1">MIGTAAAYYLAKAGHEVEVVDRRRAPAMETSYANAGEVSPGYSAPWAGPGVPLKAIKWLAMRHRPLVIRPALDPALWRWCLAMLRNCTHARYRINKGRMVRLAEYSRDCLRELRADTGIEYDARQLGTLQLFRSQRQLDDAGKDIAILRESGVAYELLDRDGCVAHEPALARVRDKFAGGLRLPGDETGDCFKFSQNLAALAQAAGARFRFDTELLGVEAEGGRWRRAHTDAGTLEADACVLALGSHSPRWLAPLGLRIPVYPVKGYSLTLPIVDAARAPESTVMDETHKVAVTRLGDRIRVGGTAELAGYDLRLHEARRRTLAHVVGDLFPGGGDDARAEFWCGLRPMTPDGTPLLGATAVRGLYLATGHGTLGWTMAAGTGRVLADLISGRAPQIDLDGLGIERYAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBV4</accession>
    <name>A0A0S2DBV4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0644</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0644"/>
    <dbReference type="EnsemblBacteria" id="ALN56002">
        <property type="protein sequence ID" value="ALN56002"/>
        <property type="gene ID" value="GLE_0644"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0644"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.633"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="189" mass="21060" checksum="C0FDA899A0C083B3" modified="2016-02-17" version="1">MKRPEPPVGALSFYAQAAQADPAWAAPWFNIGLLHKYFGDWTQSLIANREALARDAGHQGACWNLGIAATALRDWRSAREAWQRYGLPIEPGEEPLEVDCGLAPVRLDPDGRGEVVWCDRLDPARARIRNVPLPDSGHRYADIVLNDGAPNGSRRIGXXXXXXXXTRPRRGGRSRGRGLRRSYREPSRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC02</accession>
    <name>A0A0S2DC02_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_03990</name>
        <name evidence="2" type="ORF">GLE_0659</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW24956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946193.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0659"/>
    <dbReference type="EnsemblBacteria" id="ALN56017">
        <property type="protein sequence ID" value="ALN56017"/>
        <property type="gene ID" value="GLE_0659"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0659"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.648"/>
    <dbReference type="OMA" id="IAWGLAW"/>
    <dbReference type="OrthoDB" id="1679387at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="163"/>
        </location>
    </feature>
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        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="258" mass="27692" checksum="69BC1521599F6D4E" modified="2016-02-17" version="1">MRLPVLIAAALMPAVAWFSQQGYFGPDNGEISDRYPTLLVAAGYAFAIWGPIFLLDLIFAVFQLRARWREDDTLLRVRPAAAAGFMLTALWMPLFSQQWFWLALATIWLALACLAWTAAVLARDPTPLPGQALWAGFAIGLHAGWLSLAAFLNTAQVIVAYRLAPVDAMLPWSLGLFAAAALVLLAANARMRGSAGYVLAALWGLAGVYAKQSESALPGAATAAWVAVGIGGVLLAQTAWLRLHPKHRVFSGHLSPGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC64</accession>
    <name>A0A0S2DC64_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative Fis-like DNA-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">fis</name>
        <name evidence="5" type="ORF">BV903_24115</name>
        <name evidence="7" type="ORF">D9T17_23370</name>
        <name evidence="6" type="ORF">FE772_04475</name>
        <name evidence="4" type="ORF">GLE_0760</name>
        <name evidence="8" type="ORF">SAMN05421681_11421</name>
    </gene>
    <organism evidence="4 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">ATCC 29487</strain>
        </source>
    </reference>
    <reference evidence="5 11" key="3">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 11">B25</strain>
        </source>
    </reference>
    <reference evidence="7 12" key="4">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 12">OH11</strain>
        </source>
    </reference>
    <reference evidence="6 13" key="5">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 13">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transcriptional regulatory Fis family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000090">
        <property type="protein sequence ID" value="OPD61358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000059">
        <property type="protein sequence ID" value="ROU04501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNOG01000014">
        <property type="protein sequence ID" value="SDY21993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946280.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000059.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0760"/>
    <dbReference type="EnsemblBacteria" id="ALN56118">
        <property type="protein sequence ID" value="ALN56118"/>
        <property type="gene ID" value="GLE_0760"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61358">
        <property type="protein sequence ID" value="OPD61358"/>
        <property type="gene ID" value="BV903_24115"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDY21993">
        <property type="protein sequence ID" value="SDY21993"/>
        <property type="gene ID" value="SAMN05421681_11421"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0760"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.748"/>
    <dbReference type="OMA" id="MVLCEVE"/>
    <dbReference type="OrthoDB" id="1933378at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000183696">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005412">
        <property type="entry name" value="Fis_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002097">
        <property type="entry name" value="DNA-binding_Fis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01591">
        <property type="entry name" value="DNABINDNGFIS"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_8" evidence="3">
        <location>
            <begin position="47"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN56118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD61358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW25037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROU04501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="SDY21993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000183696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="90" mass="10086" checksum="C894F150B0067226" modified="2016-02-17" version="1">MNALNDRNDGARSGPRVPLRDHVATSIRRYLGDLNGSGTENLYEIALRELEIPLFAEVLQHCDGNQSRAAAMLGIHRATLRKKLREYGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC92</accession>
    <name>A0A0S2DC92_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AraC family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_0782</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949950.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0782"/>
    <dbReference type="EnsemblBacteria" id="ALN56140">
        <property type="protein sequence ID" value="ALN56140"/>
        <property type="gene ID" value="GLE_0782"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0782"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.771"/>
    <dbReference type="OMA" id="HYAMWIP"/>
    <dbReference type="OrthoDB" id="1757088at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003313">
        <property type="entry name" value="AraC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02311">
        <property type="entry name" value="AraC_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="166"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="270" mass="28604" checksum="D25013B3B89CF9EB" modified="2016-02-17" version="1">MSDPLLARERLDAADAPFLLAARLRAPGVRETPEHRHARGQLLGADRGLLSVGTGRGRWLVPASDAVWVPPHQPHSLRSHGAAFSGWSVYVAEAECAALPAQPCALAVSPLLREAVARAASWPAGASLGPAQARLAWVLIDEIALAAGGEDGGRLGLPMPQDPRLLRVAHALADAPDDPRGLAAWAGLAHLSERSLTRLFAAQTGYSLLQWRQRARLLRALERLAAGEAVTAVALACGYDSVSAFTAMFRRHLGAAPTRYLQGREDAAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCC9</accession>
    <name>A0A0S2DCC9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Threonine synthase</fullName>
            <ecNumber evidence="7">4.2.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">thrC</name>
        <name evidence="7" type="ORF">GLE_0827</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine synthase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.1" evidence="7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946328.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0827"/>
    <dbReference type="EnsemblBacteria" id="ALN56185">
        <property type="protein sequence ID" value="ALN56185"/>
        <property type="gene ID" value="GLE_0827"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0827"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.816"/>
    <dbReference type="OMA" id="CEFASSA"/>
    <dbReference type="OrthoDB" id="428821at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004795">
        <property type="term" value="F:threonine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029144">
        <property type="entry name" value="Thr_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037158">
        <property type="entry name" value="Thr_synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004450">
        <property type="entry name" value="Thr_synthase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14821">
        <property type="entry name" value="Thr_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00260">
        <property type="entry name" value="thrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thr_synth_N" evidence="6">
        <location>
            <begin position="3"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="PALP" evidence="5">
        <location>
            <begin position="90"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR604450-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN56185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="435" mass="46110" checksum="3A489DB30C6E11AD" modified="2016-02-17" version="1">MNFLSTRGQTAPTALDAALAAGLAPDGGLYVPETIPTLDRPLPARALHETAHAVLAPYFVDSALRDRLGAICAQAFSFDAPLRPLSQPDSWLLELFHGPTAAFKDYAARFLGGALSALRAPDAPDTTIVVATSGDTGAAVAAAFHRRPGFRVLILYPDGRVSPRQAHGLGCWGDNVQALRVDGDFDACQRLAKQALSDEALRAQLPLSSANSISLGRLLPQAAYYAHTAARYYADHGEPLNFIVPTGNLGNACAALVAKRMGAPVGELRLSTNANDTLPRYFAGADYSAQPTRATLANAMDVGAPSNFERLRHWHRDDAELRAAIHAEGVDDATIEQTIRAAPQRYGIVPCPHTATGLRVLETLRAQGDERPWAVVATAHPSKFDSIVEPLVGHAVQPPPALAESLARPASAEPMAANYAALRERLLAGATVVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCJ9</accession>
    <name>A0A0S2DCJ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0907</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0907"/>
    <dbReference type="EnsemblBacteria" id="ALN56265">
        <property type="protein sequence ID" value="ALN56265"/>
        <property type="gene ID" value="GLE_0907"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0907"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.895"/>
    <dbReference type="OMA" id="GFFLHTD"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="30"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="156" mass="17355" checksum="4F2296A4D660B58D" modified="2016-02-17" version="1">MCLGGGPTRRGFDYDRNVFPCPQGLRMNRSIGSITLVVDDYDRAIDYYTRALGFALLEDIDLGGGKRWVRVAPAAGAQTALLLAQAADENQRARIGDQTGGRVGFFLHTDDFHRDHAAMRAQGVRFLESPRVETYGTVAVFEDLYGNRWDLLELKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCM7</accession>
    <name>A0A0S2DCM7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CDP-alcohol phosphatidyltransferase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">CDP-alcohol phosphatidyltransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_04430</name>
        <name evidence="2" type="ORF">GLE_0751</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946271.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0751"/>
    <dbReference type="EnsemblBacteria" id="ALN56109">
        <property type="protein sequence ID" value="ALN56109"/>
        <property type="gene ID" value="GLE_0751"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0751"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.739"/>
    <dbReference type="OMA" id="RMALNAV"/>
    <dbReference type="OrthoDB" id="1232102at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016780">
        <property type="term" value="F:phosphotransferase activity, for other substituted phosphate groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="215" mass="22933" checksum="B1AB4172B2CF02E8" modified="2016-02-17" version="1">MASIYALKGRFQDLLRPLVRRLHAAGATANQVTVAAALVSLAVAALVYWGAPARPWLFALLPLWMFARMALNAIDGMLAREFGQQSRLGAYLNELCDVVSDSALYLSLLALAGLHAAPLLAFVLLAALTEYAGVLGLMVGAPRRYDGPMGKSDRAFVIGALGLLLALGWISAWPVEIALALASMLCAWTVVRRVRAGLRHDAAPGAVSVRQGERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCR1</accession>
    <name>A0A0S2DCR1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Inosine-uridine preferring nucleoside hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Nucleoside hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_05270</name>
        <name evidence="2" type="ORF">GLE_0924</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946399.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0924"/>
    <dbReference type="EnsemblBacteria" id="ALN56282">
        <property type="protein sequence ID" value="ALN56282"/>
        <property type="gene ID" value="GLE_0924"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0924"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.912"/>
    <dbReference type="OMA" id="NEYTCPT"/>
    <dbReference type="OrthoDB" id="1763387at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016799">
        <property type="term" value="F:hydrolase activity, hydrolyzing N-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.245.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001910">
        <property type="entry name" value="Inosine/uridine_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036452">
        <property type="entry name" value="Ribo_hydro-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01156">
        <property type="entry name" value="IU_nuc_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53590">
        <property type="entry name" value="SSF53590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IU_nuc_hydro" evidence="1">
        <location>
            <begin position="8"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="311" mass="33583" checksum="B762063E48359D7F" modified="2016-02-17" version="1">MTDRIPLLIDTDPGVDDALALLMAFNDPRHQIVGLTIAAGNVGLKHTVANALKLCEVAGQDIPVFAGADAPLLHPSPDAGYVHGQDGFGDVGYEAAKRQVEAEHAALAIIRLSHQHAGKLLLVALGPLTNVALALKLDPTLPQRIARLVVMGGAVTCQGNITPAAEFNIYFDPEAAHIVFEAFERIDLADWEAVMAHGLHHDRVVGWLAAGAERGRFYERISEKTRLWSIDRRGDEWHAADALAMAFALEPDGALGVQDRPVSIELDGTHSRGATVVDWRRQEGRADKVSILMKYDQARFERLIAAALAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD30</accession>
    <name>A0A0S2DD30_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Transporter, major facilitator family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_06015</name>
        <name evidence="7" type="ORF">GLE_1092</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946519.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1092"/>
    <dbReference type="EnsemblBacteria" id="ALN56450">
        <property type="protein sequence ID" value="ALN56450"/>
        <property type="gene ID" value="GLE_1092"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1092"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1079"/>
    <dbReference type="OMA" id="WTMATAT"/>
    <dbReference type="OrthoDB" id="1384345at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="320"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="354"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="4"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN56450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW25283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="390" mass="40047" checksum="C292F80EBAE88D3D" modified="2016-02-17" version="1">MLLPLILLSAAGFTVLTTEFILVGLLPSLSRDLGVSVSQAGLLVTLFAFAVAASGPFLTAYFARFERKRLFIVVLLLFAASNVVAAMAPNLGVMAFARLIPALGVPVFWALASETAVDIAGQDRAGKAISMISFGVICATVIGVPTGTLIADAFGWRAAFVALAVASLLKAGMLYAFLPDSRGAQPPKLGEQFRVLRDPRVVGHVLMSVILFAGMFTAYTYLADMFERLAGLNGAVVGWALMAFGAVGLIGNTLGGRIVDRHPLRASLIFSVPLAMGLVLVVPSVQTLPLFAVALALWGITQAALFPVSHVRVMKSAPQAPAFAAALNVSGANLGIGVGAIVGGRVIDAVGVGGVGYAAAALVGLSVVVGFVLMSVGQPAQADAEPECAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DD80</accession>
    <name>A0A0S2DD80_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">O-succinylhomoserine (Thiol)-lyase</fullName>
            <ecNumber evidence="5">2.5.1.48</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">metB</name>
        <name evidence="6" type="ORF">FE772_06155</name>
        <name evidence="5" type="ORF">GLE_1123</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.48" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946539.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1123"/>
    <dbReference type="EnsemblBacteria" id="ALN56481">
        <property type="protein sequence ID" value="ALN56481"/>
        <property type="gene ID" value="GLE_1123"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1123"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1109"/>
    <dbReference type="OMA" id="YKQDGVG"/>
    <dbReference type="OrthoDB" id="637281at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003962">
        <property type="term" value="F:cystathionine gamma-synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102028">
        <property type="term" value="F:cystathionine gamma-synthase activity (acts on O-phosphohomoserine)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011821">
        <property type="entry name" value="O_succ_thio_ly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="PTHR11808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02080">
        <property type="entry name" value="O_succ_thio_ly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="374"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW25305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="403" mass="42340" checksum="ACC03DB70BF9717B" modified="2016-02-17" version="1">MSNDTIQTPTRNACTAAVRAGIDRDAAYGAVTPPIVLSSNFSFAGFNDKRQYDYTRSGNPTRDLLGEALAELEGGAGGVITSTGMSAITLVLHAFLKPGDRIVVPHDGYGGSWRLFNALAAKGAFELITADLTDPRSLTEALATNPAVVWIETPSNPLLRITDLRFVIEAAQAKGALTVVDNTFLSPALQRPIAFGADLVVHSTTKYINGHSDVVGGAVVAKSEDHHQKLIWWANALGLTGSPFDAFLTLRGLRTLDARLRVHQENTQAIAELLDAHPAVRVVHYPGLASHPGHALAARQQKGFGAMLSVEIDGGVDAVRAFVDGLSCFTLAESLGGVESLVAHPATMTHAAMSPEARAAAGIGDGLLRLSVGIEHVDDLIADLQAALDRASAAVATAARAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDC4</accession>
    <name>A0A0S2DDC4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Magnesium transporter MgtE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mgtE</name>
        <name evidence="10" type="ORF">BV903_16340</name>
        <name evidence="11" type="ORF">FE772_06430</name>
        <name evidence="9" type="ORF">GLE_1182</name>
    </gene>
    <organism evidence="9 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">C3</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts as a magnesium transporter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SLC41A transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000043">
        <property type="protein sequence ID" value="OPD62848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946577.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1182"/>
    <dbReference type="EnsemblBacteria" id="ALN56540">
        <property type="protein sequence ID" value="ALN56540"/>
        <property type="gene ID" value="GLE_1182"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62848">
        <property type="protein sequence ID" value="OPD62848"/>
        <property type="gene ID" value="BV903_16340"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1182"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1167"/>
    <dbReference type="OMA" id="TMTVAVR"/>
    <dbReference type="OrthoDB" id="1239195at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.60.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006668">
        <property type="entry name" value="Mg_transptr_MgtE_intracell_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038076">
        <property type="entry name" value="MgtE_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006669">
        <property type="entry name" value="MgtE_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006667">
        <property type="entry name" value="SLC41_membr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036739">
        <property type="entry name" value="SLC41_membr_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43773">
        <property type="entry name" value="PTHR43773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01769">
        <property type="entry name" value="MgtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03448">
        <property type="entry name" value="MgtE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00924">
        <property type="entry name" value="MgtE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161093">
        <property type="entry name" value="SSF161093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00400">
        <property type="entry name" value="mgtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="289"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="313"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="392"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="428"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="8">
        <location>
            <begin position="143"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="8">
        <location>
            <begin position="207"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD62848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW25351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="453" mass="49031" checksum="7B60CEA833E3D99F" modified="2016-02-17" version="1">MAEAVRHDKTARQLRLLSDALDSGRLGPVRRLVNTLSPAEIGNLLESLPPGKRQVVWGLVDPEDDGEVLVHVGEEVRESLLADMDTDEIVAAVEDLDIDDLADLVEDLPDTVIDEVLKSMDRENRERLEQVLSYPEDTAGRLMNPDVVTVRADTTIDVVLRYLRLRGELPEHTDHLYVVSRRHQYLGRIALAALLTHEPGTAINKLIDDEQPAIDVGETAGEVARQFSDHDWISAPVVDDNNILLGRITIDDVVDIIREEAEHQALSAAGLDEDEDLFSPVRRAFRRRLIWLSVNLCTAFLAASVVGQFEDSIAKLVALAALMPIVAGMGGNAGTQVLALMIRGLALGQIGASNVGVLLRKELSVALINGLVLGIGLGLIVLIWFRQPGLSFVIGSALTINLLTAATGGVLVPITLKRLGFDPALAGGVILTTLTDVMGFLSFLGLATLILLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDC7</accession>
    <name>A0A0S2DDC7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PilT/PilU family type 4a pilus ATPase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Type IV pili twitching motility protein PilT</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Type IV pilus assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pilU</name>
        <name evidence="4" type="ORF">BV903_16280</name>
        <name evidence="5" type="ORF">FE772_06345</name>
        <name evidence="3" type="ORF">GLE_1164</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000043">
        <property type="protein sequence ID" value="OPD62838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946566.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1164"/>
    <dbReference type="EnsemblBacteria" id="ALN56522">
        <property type="protein sequence ID" value="ALN56522"/>
        <property type="gene ID" value="GLE_1164"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62838">
        <property type="protein sequence ID" value="OPD62838"/>
        <property type="gene ID" value="BV903_16280"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1164"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1149"/>
    <dbReference type="OMA" id="QGLCRTT"/>
    <dbReference type="OrthoDB" id="473670at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006321">
        <property type="entry name" value="PilT/PilU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01420">
        <property type="entry name" value="pilT_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="130"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD62838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="388" mass="43065" checksum="4F3FB763C76DEBCB" modified="2016-02-17" version="1">MNTPAPSNPTTASGAIDFTSFLKLMAHQRASDLFITAGMPPSMKVHGKITPITQNPLTPQQSRDLVLNVMSPQQREEFEKTHECNFAIGVTGVGRFRVSCFYQRNQVGMVLRRIETKIPSVDELNLPPIIKTLAMTKRGIIIFVGATGTGKSTSLAAMIGYRNQNSTGHIITIEDPIEFVHRHEGCIITQREVGIDTDSWEAALKNTLRQAPDVIMIGEVRTREGMDHAIAFAETGHLVLCTLHANNANQAMDRIINFFPEDRRNQLLMDLSLNLKGVVAQQLIPTPDGKGRRVAMEILLGTPLAQDYIRDGEIHKLKELMKESTQLGMKTFDQALFELYQGGEISYEDALRYADSQNEVRLRIKLAQGGDARTLSQGLDGVEVAEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDI3</accession>
    <name>A0A0S2DDI3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_1153</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1153"/>
    <dbReference type="EnsemblBacteria" id="ALN56511">
        <property type="protein sequence ID" value="ALN56511"/>
        <property type="gene ID" value="GLE_1153"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1153"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1138"/>
    <dbReference type="OMA" id="FWRSLHP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="292" mass="31941" checksum="6C733D2F86367181" modified="2016-02-17" version="1">MSPRPHLPAARAPATSGKAFAAAGDDAHGFDASFVADVLAQALAIRAPAGRARVFAISGLQGSGKSTLAAQLAAAAQAHGLRTAVLSIDDFYLGRRERQRLGRQVHPLLATRGPPGTHDVALACALLDELRHRAAVRLPRFDKLADTRLPPSRWPRANAVDLVVFEGWFLGAPAQDTAQLAEPVNALERDEDAHGVWRAYCNRALAADYPPLWSRLDRLLFLQPPGFEVVAGWRWQQEQALQARHPHRQGMTRAQVQRFVSLFERVSRQALATLPGIADRTVVLDAQRRPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDL8</accession>
    <name>A0A0S2DDL8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PIN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_06860</name>
        <name evidence="2" type="ORF">GLE_1272</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946646.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1272"/>
    <dbReference type="EnsemblBacteria" id="ALN56629">
        <property type="protein sequence ID" value="ALN56629"/>
        <property type="gene ID" value="GLE_1272"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1272"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1255"/>
    <dbReference type="OMA" id="DSNIWVD"/>
    <dbReference type="OrthoDB" id="2034229at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002850">
        <property type="entry name" value="PIN_toxin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34610">
        <property type="entry name" value="PTHR34610"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13470">
        <property type="entry name" value="PIN_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="6"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="151" mass="16626" checksum="2E076E69E917C300" modified="2016-02-17" version="1">MSAAPRIVLDSNVCLDLFAFGDPAVAPLLHALRSGAVAAVTDAPCREEWQRILDYPQLALDPAARARCLREYDQALRPFAHDGAGETKLPRCADPDDQKFLELAHAAGARWLLSRDHALVVLGRRTARAGWFEIMTPRTWVALEAWRSPGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDN5</accession>
    <name>A0A0S2DDN5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Motor switch protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="14">OmpA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">motA</name>
        <name evidence="14" type="ORF">FE772_07025</name>
        <name evidence="13" type="ORF">GLE_1309</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">C3</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946677.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1309"/>
    <dbReference type="EnsemblBacteria" id="ALN56666">
        <property type="protein sequence ID" value="ALN56666"/>
        <property type="gene ID" value="GLE_1309"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1309"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1293"/>
    <dbReference type="OMA" id="MYRINDA"/>
    <dbReference type="OrthoDB" id="583204at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028974">
        <property type="entry name" value="TSP_type-3_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103647">
        <property type="entry name" value="SSF103647"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0626">Porin</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242192" evidence="11">
        <location>
            <begin position="23"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="12">
        <location>
            <begin position="240"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="324"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN56666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW25453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="359" mass="38927" checksum="C83E730B421C741E" modified="2016-02-17" version="1">MNKKLLCAALLGGLSLAQVASAQDFDDRWYLTGAAGMNIQDNDRGTRNAPFGAIGLGKFLNKNWSLDGELNYQNPKFDANQDANWSQYGISLDLRRHFVTDGRNWNPYILMGLGYQRSEEEYFIPSPLSPGNRKDGNFAAKVGVGIQGDLGRVGIRTELAYRADFDDQSVNAPQEDWFGDVLASVGIVVPLGPEPAAPVVAPPPVQAGCADKDDDGDGVNNCDDKCPNSQAGQTIGPDGCPVPVTIDLKGVNFDFDKATLRPDAVAILNEATEILKRYPELKVEVAGHTDLCGKDAYNQKLSERRAKAAYDYLTSNGVDAGRLNGPIGYGESRPLEQTSQTLPGCKSEKNRRTELNVQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDS7</accession>
    <name>A0A0S2DDS7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1218</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1218"/>
    <dbReference type="EnsemblBacteria" id="ALN56575">
        <property type="protein sequence ID" value="ALN56575"/>
        <property type="gene ID" value="GLE_1218"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1218"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1203"/>
    <dbReference type="OMA" id="WDTQWDM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014509">
        <property type="entry name" value="UCP020606"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09997">
        <property type="entry name" value="DUF2238"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="208" mass="23787" checksum="0D9B106E5D2BF430" modified="2016-02-17" version="1">MPVAQGRMSAPKKAALGFVLAVFAITWIAPKSPFEQAMHSVLTVLGLFWLWRHDRRWPLRDAHFLAICGFMTAHCIAARWLYSYVPYDQWIQWLSGGWSLDRALGFQRNHFDRLIHFLYGACFAPPLREYFRQRWPALGAGQAFVLAVAAIMCTSLVYEWFEWAIALTMSPQDAESYNGQQGDVWDAHTDMFLATLGSLAAWPRKRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDU9</accession>
    <name>A0A0S2DDU9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inner membrane protein YtfF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ytfF</name>
        <name evidence="3" type="ORF">GLE_1270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1270"/>
    <dbReference type="EnsemblBacteria" id="ALN56627">
        <property type="protein sequence ID" value="ALN56627"/>
        <property type="gene ID" value="GLE_1270"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1270"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1253"/>
    <dbReference type="OMA" id="WYPLRNA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="38"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="358" mass="39168" checksum="AC082AD3A3042DD8" modified="2016-02-17" version="1">MQAYGRGSRRSYRRYRRPTAIWYKTPPRPPRDPAAMLLGTLYALLAGLIWGLVFVGPLLLPEYPAALQSVGRYLAFGLIALPLAWLDRKALRQLGRADWIEALKLSLIGNLLYYLCLASAIQRAGGPLPTMIIGTLPVIIAISANLRNARRDGRLPWARLAPSLLLIALGIACVNRAELRELQSQSHADLGRYAVGGLLAFGAVICWTWYPLRNADWLRAHPDRSPRSWATAQGVATLPLALAGYIALWLYMSATHSPFPMPFGPRAGYFVALMVAIGLLASWVGTLCWNEASQRLPTALAGQLIVFETLFALTYAFMLRGQWPPALTLAGIGLLVAGVLWALRIKPVPPEVAVESAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE00</accession>
    <name>A0A0S2DE00_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1347</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56704">
        <property type="protein sequence ID" value="ALN56704"/>
        <property type="gene ID" value="GLE_1347"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1347"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1329"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="106" mass="11205" checksum="1E7AA37DCA32E496" modified="2016-02-17" version="1">MDRRETGDFNGCGGQGFCGGRLGASARPCPGAFTVIPAKAGTHFDLASGLPAEPAGYRRAKRKSKWVPAFAGMTGLEKTAPPVRRCANLPTVPLPARRPTRRNALN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE12</accession>
    <name>A0A0S2DE12_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polyhydroxyalkanoate depolymerase, intracellular</fullName>
            <ecNumber evidence="2">3.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">phaZ</name>
        <name evidence="2" type="ORF">GLE_1434</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1434"/>
    <dbReference type="EnsemblBacteria" id="ALN56791">
        <property type="protein sequence ID" value="ALN56791"/>
        <property type="gene ID" value="GLE_1434"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1434"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1415"/>
    <dbReference type="OMA" id="FYLQTVE"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009656">
        <property type="entry name" value="PHB_depo_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010915">
        <property type="entry name" value="PHB_depoly_PhaZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06850">
        <property type="entry name" value="PHB_depo_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF020818">
        <property type="entry name" value="PHB_depoly_PhaZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01849">
        <property type="entry name" value="PHB_depoly_PhaZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHB_depo_C" evidence="1">
        <location>
            <begin position="212"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="415" mass="46990" checksum="17435E17D449FE66" modified="2016-02-17" version="1">MLLYQMHELGRAWMAPMTYWADAGAKMFAAPGSWLSTLPGASRVAAGCELLYRIGKDYEKPEFGIHSIQIDGNAYPVIEREMARKPFCRLLRFKRYADDAGNIAELKDDPPVLVVAPLSGHHATLLRDTVRTLLRDHKVYITDWIDARMVPNEEGAFTLDDYIGYIQDFIRQIGADSLHVISVCQPTVPVLAAVSLMAARGEPTPRSLVMMGGPIDTRESPTQVNDLAEHKPLWWFENNLIHHVPANFPGRGRRVYPGFLQHSGFVAMNPERHFQSHWDFYQDLLKGDLEDAESHRRFYDEYNAVLDMPAEYYLDTIRVVFQEHLLPRGLWDVAGERVNPGAINNTALLTIEGELDDISGQGQTRAAHTLCTGVAESQRQHITVDGAGHYGIFSGRRWREQVYPQVRDFIARYSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE38</accession>
    <name>A0A0S2DE38_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD(P)H-dependent oxidoreductase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">NADPH-dependent FMN reductase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_07625</name>
        <name evidence="2" type="ORF">GLE_1450</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946783.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1450"/>
    <dbReference type="EnsemblBacteria" id="ALN56807">
        <property type="protein sequence ID" value="ALN56807"/>
        <property type="gene ID" value="GLE_1450"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1450"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1430"/>
    <dbReference type="OMA" id="HNGAYTT"/>
    <dbReference type="OrthoDB" id="1818437at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_red" evidence="1">
        <location>
            <begin position="11"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="200" mass="21243" checksum="C2D80BAEEDE25F45" modified="2016-02-17" version="1">MSASPTVSPPRLLAFAGSLRSGSYNRRLIPVLAEGARAAGAEVELIELRDYALPVYDGDIEAEAMPPNARRLQELMARHDGLLISTPEYNGSMPALVKNTLDWISRPLPDGRSGTTLFADKVAGIVSASPGPLGGLRSLLVLRDALAKLGLIVVPQQVAVGQAGDKLHDYGELSDERQREAVHRVGAAVVRHLRVQGAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE92</accession>
    <name>A0A0S2DE92_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTPase HflX</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP-binding protein HflX</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 10" type="primary">hflX</name>
        <name evidence="11" type="ORF">BV903_21780</name>
        <name evidence="10" type="ORF">GLE_1511</name>
    </gene>
    <organism evidence="10 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">C3</strain>
        </source>
    </reference>
    <reference evidence="11 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">B25</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer. Associates with the 50S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="5">May associate with membranes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000072">
        <property type="protein sequence ID" value="OPD61807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946836.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000072.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1511"/>
    <dbReference type="EnsemblBacteria" id="ALN56868">
        <property type="protein sequence ID" value="ALN56868"/>
        <property type="gene ID" value="GLE_1511"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61807">
        <property type="protein sequence ID" value="OPD61807"/>
        <property type="gene ID" value="BV903_21780"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1511"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1492"/>
    <dbReference type="OMA" id="AEMKTGR"/>
    <dbReference type="OrthoDB" id="1592033at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01878">
        <property type="entry name" value="HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00900">
        <property type="entry name" value="GTPase_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030394">
        <property type="entry name" value="G_HFLX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032305">
        <property type="entry name" value="GTP-bd_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016496">
        <property type="entry name" value="GTPase_HflX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025121">
        <property type="entry name" value="GTPase_HflX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042108">
        <property type="entry name" value="GTPase_HflX_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10229">
        <property type="entry name" value="PTHR10229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16360">
        <property type="entry name" value="GTP-bdg_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13167">
        <property type="entry name" value="GTP-bdg_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006809">
        <property type="entry name" value="GTP-binding_hflX_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03156">
        <property type="entry name" value="GTP_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51705">
        <property type="entry name" value="G_HFLX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hflx-type G" evidence="9">
        <location>
            <begin position="199"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="158"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="205"/>
            <end position="212"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="230"/>
            <end position="234"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="251"/>
            <end position="254"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="317"/>
            <end position="320"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="342"/>
            <end position="344"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR006809-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR006809-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN56868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OPD61807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="432" mass="47408" checksum="C05DC4EABE6FC297" modified="2016-02-17" version="1">MFERSKRGEHALLIQPHSGGAPEEDLLEEFADLARSAGASVAAVLTARIDRPNAAILIGSGKLEEVKAAAEASGADLILVNHPLSPGQERNLERALQRRVVDRTGLILDIFSQRARSAEGKLQVELAQLKHMATRLVRGWTHLERQRGGSIGLRGPGETQLETDRRLLQKRLEQLQKRLDKVEVQRTQMRRARVRSELPRVALVGYTNAGKSTLFNALTGADAYAADQLFATLDPTVRRIELAGGGVVLADTVGFVRDLPHELVAAFRSTLSEAREADLLLHVIDAADPLRDERIAQVDAVLAEIGAGDLPQLLVFNKIDRLDGVAPRIDRPGEERHRVWLSARTGEGLATLRDALGEALQLRRVQGGLRIAPQDARLRARLHDLGAVRAEQADEHGWWVEVDLAVADAQRLFAQAHGEPLRPLLETAETPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEC1</accession>
    <name>A0A0S2DEC1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Amidophosphoribosyltransferase</fullName>
            <shortName evidence="5">ATase</shortName>
            <ecNumber evidence="5">2.4.2.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Glutamine phosphoribosylpyrophosphate amidotransferase</fullName>
            <shortName evidence="5">GPATase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 10" type="primary">purF</name>
        <name evidence="11" type="ORF">BV903_21370</name>
        <name evidence="12" type="ORF">FE772_07135</name>
        <name evidence="10" type="ORF">GLE_1339</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">C3</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>5-phospho-beta-D-ribosylamine + diphosphate + L-glutamate = 5-phospho-alpha-D-ribose 1-diphosphate + H2O + L-glutamine</text>
            <dbReference type="Rhea" id="RHEA:14905"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58681"/>
            <dbReference type="EC" id="2.4.2.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5 8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 5 6">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 6">In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.14" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000070">
        <property type="protein sequence ID" value="OPD61878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946699.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000070.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1339"/>
    <dbReference type="EnsemblBacteria" id="ALN56696">
        <property type="protein sequence ID" value="ALN56696"/>
        <property type="gene ID" value="GLE_1339"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61878">
        <property type="protein sequence ID" value="OPD61878"/>
        <property type="gene ID" value="BV903_21370"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1339"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1321"/>
    <dbReference type="OMA" id="ENAQPTF"/>
    <dbReference type="OrthoDB" id="267682at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00124"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004044">
        <property type="term" value="F:amidophosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00715">
        <property type="entry name" value="GPATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01931">
        <property type="entry name" value="PurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005854">
        <property type="entry name" value="PurF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035584">
        <property type="entry name" value="PurF_N"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000485">
        <property type="entry name" value="Amd_phspho_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01134">
        <property type="entry name" value="purF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5 6 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5 6" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="9">
        <location>
            <begin position="2"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5 7">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="363"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="364"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000485-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000485-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN56696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OPD61878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW25471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="489" mass="54163" checksum="F30E40F6E124D22D" modified="2016-02-17" version="1">MCGILGIVGNTDVAAQLYDGLTVLQHRGQDAAGIATADGARLRVHKGNGLVSDVFDEASMRLLEGRVGIGHCRYPTAGSEGSDEAQPFYVNSPYGIALAHNGNLINTDTLRREVFEQDRRNINTESDSEVLLNVFAHELDRQRALTPEAAFAAIEGVHRRCVGGYAVVATVLGLGLVAFRDPHGIRPLVLGKRRIGNQDEYAVASESVALDLLGFERVRDVRPGEGIVVTARGELFSRQCAEVRKHTPCIFEYVYFARPDSMMDDVSVHKARMRMGQTLGEKILRLRPDHDIDVVIPIPDTSRDSALEIANTLGVKYREGFIKNRYVGRTFIMPGQGERAKSVRRKLNPIPLEFRNRVVLLVDDSIVRGTTSRQIVQMARDAGARKVYLASAAPAVRHPNIYGIDMPSAEELVAHGRSDEQVQELLGCDWLIYQDLDALEQAVSGPKHRIDHFDSSCFNGEYVTGVEPGYFERIQQMRSDDAKKTRRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEF3</accession>
    <name>A0A0S2DEF3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_08060</name>
        <name evidence="3" type="ORF">GLE_1540</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946862.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1540"/>
    <dbReference type="EnsemblBacteria" id="ALN56897">
        <property type="protein sequence ID" value="ALN56897"/>
        <property type="gene ID" value="GLE_1540"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1540"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1522"/>
    <dbReference type="OMA" id="TRAYLEI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010559">
        <property type="entry name" value="Sig_transdc_His_kin_internal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06580">
        <property type="entry name" value="His_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="316"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="419" mass="46525" checksum="2DD551D276560282" modified="2016-02-17" version="1">MIRNLFFVARIAAAWFGLFVLLALIVSAVPLLNRMDTGPLFVIALLVVIYVSIKAFSHLRRVRLIAERVDATTRANRQRRQIDVPFEVEETFELLEAAIRDLPRVEDIESARDSLQVRAKVQRADQARMLDLQGADPHSWKYGLARNQVLATIDPSADGSRITLICEPEVGPWSDWFCVDQGTNLENAEALSRAIARRVAERHRGERTQAARTATEKELAVAKLSLLHAQVEPHFLYNTLASAQYLTRHDPPRADEMLGHLIEFLRRSLPRTEDALSTLGDELERSRAYLEILKLRMGQRLQTQIDVPEDLRALPLPPMILQTLAENAIKHGLEPKPGGGTVWIRARNGESGVSITVADDGMGLNSLNSGSGIGLNNVRERLRLVYGDRAQLSIVANFPSGVAATIVVPAPSGEEQARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEF5</accession>
    <name>A0A0S2DEF5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_08280</name>
        <name evidence="2" type="ORF">GLE_1591</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946904.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56948">
        <property type="protein sequence ID" value="ALN56948"/>
        <property type="gene ID" value="GLE_1591"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1591"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1571"/>
    <dbReference type="OrthoDB" id="1926680at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="148" mass="15148" checksum="CF615BBD1ACB5237" modified="2016-02-17" version="1">MNETQGYAVFFFPQALEALGEAIRPYLLDGPGGPHVLCKEIDTGGAFTEMTLEGRTSEGRDLTLELMVPGNMVRMIVSAHGEGSFGFGPRNAPRPAAKPVAAAPAPAAVPASSPAQPQSPPVVPTPDAPAPAVPDAPSPVIASEGKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEI3</accession>
    <name>A0A0S2DEI3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Three-Cys-motif partner protein TcmP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">tcmP</name>
        <name evidence="2" type="ORF">FE772_07665</name>
        <name evidence="1" type="ORF">GLE_1457</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946791.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56814">
        <property type="protein sequence ID" value="ALN56814"/>
        <property type="gene ID" value="GLE_1457"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1457"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1437"/>
    <dbReference type="OMA" id="FNLDQCG"/>
    <dbReference type="OrthoDB" id="510345at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031009">
        <property type="entry name" value="Tcm_partner"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04474">
        <property type="entry name" value="tcm_partner"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="427" mass="48764" checksum="DA15E566B95764E9" modified="2016-02-17" version="1">MTQSPYRWNDYEPAIIKQHSIAKHDVLREYLVAYLQTLVNNPGQDTISVTLVDGFAGGGLYIHERTKQLVPGSPFIFLEAAKEAQALLSLDRKKPLHFNLDYFFVEKERAACEFLSKSLADRGYQDRIGQDIRVLHGTFESHYPQILKFIKAKNPIVGRSIFLLDQYGYKDVPTPQIRQIFEKLPRAEVILTFAVDAFINFASDSPATARQLKRLDIPDLLRGRTFQDIKSNEKDVRLYIQSCMYEALVKSCGARYFTVFFIRTTGHGDYWLVHLSQHHRARDVMTTVHWNNNNHFIHYGGAGLNMFRALGYTARDDAEFTGQGELGFCFDEVASNASVHTLATQIAPVVYERKDGISFGELFARHCNSSPADSSRYRMAIEKLIEHKELIVLGEKGERRKRASTIKERDVLKVSGQTILWPFSTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF11</accession>
    <name>A0A0S2DF11_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phospholipase C</fullName>
            <ecNumber evidence="2">3.1.4.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">plcN</name>
        <name evidence="6" type="ORF">FE772_08115</name>
        <name evidence="5" type="ORF">GLE_1552</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial phospholipase C family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946871.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1552"/>
    <dbReference type="EnsemblBacteria" id="ALN56909">
        <property type="protein sequence ID" value="ALN56909"/>
        <property type="gene ID" value="GLE_1552"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1552"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1534"/>
    <dbReference type="OMA" id="LPWYLGY"/>
    <dbReference type="OrthoDB" id="250274at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:phosphatidylcholine phospholipase C activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017767">
        <property type="entry name" value="Bact_PC-PLC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007312">
        <property type="entry name" value="Phosphoesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008475">
        <property type="entry name" value="PLipase_C_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956">
        <property type="entry name" value="PTHR31956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05506">
        <property type="entry name" value="DUF756"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04185">
        <property type="entry name" value="Phosphoesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PC_PLC"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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    <feature type="domain" description="DUF756" evidence="4">
        <location>
            <begin position="504"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="DUF756" evidence="4">
        <location>
            <begin position="609"/>
            <end position="682"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW25637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="696" mass="77164" checksum="B599E533FDE97453" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFK0</accession>
    <name>A0A0S2DFK0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2001</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="273" mass="29842" checksum="9D7557D719D90666" modified="2016-02-17" version="1">MLTRPDAEALRAARDAGRASWSGSLDLGRSQGEARLAADGWEWRGQRYRYPDALKDRTVYYWDGEDYAAVSRFAGSLIKLVPTQWGAPTFEIDGIKMLPTAKTSPIDDARRKVGLIEARGKTVLDTCGGLGYFAACCLEAGAARIESFEKNASVLWLRTLNPWSPDPDAADSGGRLQLTHADVSQAIAALPAAGFDALLHDPPRFGIAGELYSQAFYDQLARVLRRGGRLFHYTGSPNKLTTGRDVPREVAKRLEKSGFKAELALDGVLAVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFK3</accession>
    <name>A0A0S2DFK3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2015</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN57365">
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        <property type="gene ID" value="GLE_2015"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01839">
        <property type="entry name" value="FG-GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="31"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="571" mass="59871" checksum="3B4F7C78DAC8BBF1" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-06-17" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFL9</accession>
    <name>A0A0S2DFL9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2031</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57381">
        <property type="protein sequence ID" value="ALN57381"/>
        <property type="gene ID" value="GLE_2031"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2031"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1996"/>
    <dbReference type="OrthoDB" id="1980667at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="251" mass="27589" checksum="F460CD12F5ECCCA2" modified="2016-02-17" version="1">MLAAAAAAVVATGGDAPPSGWVAIDPPRSEAALRCANYSQQEWSVRRAADGTPELVQVRHEHRYLTVRELFDDGALLGYNRGEFGGWIEWLPRDGGARFEQTQVDPVAATRYRGEAVIAEGLAHLDANRGSVLRFERRDGRSWRIHRLAELDAAPVAAVRRGDKEWVLLLVDGVASVQLDSGQVRRLHRSRDWLGSYVGSIQPLGDGWLIGGRRGALRLEATADGGYRERWWTPARCAVLEPVCSCADSIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFN1</accession>
    <name>A0A0S2DFN1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, LuxR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_2112</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2112"/>
    <dbReference type="EnsemblBacteria" id="ALN57462">
        <property type="protein sequence ID" value="ALN57462"/>
        <property type="gene ID" value="GLE_2112"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2112"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2076"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
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        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
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        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="SMART" id="SM00421">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="164"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="231" mass="25175" checksum="7E031D4C81FDEE26" modified="2016-02-17" version="1">MEGAVSRERPGGARTQSPQAPGCKQYLEDVLHKLQALVAPGHDLAEEQQAATRALFADFISGCLQMYFLHGGGTGLLAAPPWPEAAAPDPRAAKERTPHERPWYLSEVAAAPKPAETSRAIAPAYPASALDASTRHAAAYPEPAAHTPRPHPLQPLRPLPVPALFERANELTEREKEVLQWIAEGRTSREVGLILSIAERTVKFHLRNIYAKLNVLNRTQAVSIANRMNLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFS8</accession>
    <name>A0A0S2DFS8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Linear gramicidin dehydrogenase LgrE</fullName>
            <ecNumber evidence="3">1.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lgrE</name>
        <name evidence="3" type="ORF">GLE_2111</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioesterase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.-.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947290.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2111"/>
    <dbReference type="EnsemblBacteria" id="ALN57461">
        <property type="protein sequence ID" value="ALN57461"/>
        <property type="gene ID" value="GLE_2111"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2111"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2075"/>
    <dbReference type="OMA" id="ALCRLIC"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012223">
        <property type="entry name" value="TEII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11487">
        <property type="entry name" value="PTHR11487"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioesterase" evidence="2">
        <location>
            <begin position="35"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="271" mass="30009" checksum="C8A50C4A19DCA861" modified="2016-02-17" version="1">MPTSYPLSSPSHLPSDPPRLPWLLRRPGAPRALRLYGFAYAGGDAGMYLSWQPALGAQIEVCGVQLPGRGVRLREPPADAMEPLVERLAADIAAQPRQPFALFGHSLGALLAFEVARRLQRLGAPAPLHLFVSACEAPGYRREGRNLHRLPDEALIEVLRDYNGTPAEVLRDREFMALVLPTLRADFALACEYAYRPGPKLRVPMSVLVGEREREGRWSEVGRWADQTEAGCELHRFDGGHLFVDSHRAAVVDRVRETLSRAMPAPRTLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFY7</accession>
    <name>A0A0S2DFY7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Beta-ketoacyl synthase/short chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">GLE_2099</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947278.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2099"/>
    <dbReference type="EnsemblBacteria" id="ALN57449">
        <property type="protein sequence ID" value="ALN57449"/>
        <property type="gene ID" value="GLE_2099"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2099"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2063"/>
    <dbReference type="OMA" id="ITGLEWI"/>
    <dbReference type="OrthoDB" id="1123553at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.110">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032821">
        <property type="entry name" value="PKS_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020807">
        <property type="entry name" value="PKS_dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042104">
        <property type="entry name" value="PKS_dehydratase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16197">
        <property type="entry name" value="KAsynt_C_assoc"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14765">
        <property type="entry name" value="PS-DH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00826">
        <property type="entry name" value="PKS_DH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 7" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carrier" evidence="9">
        <location>
            <begin position="1426"/>
            <end position="1501"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="9">
        <location>
            <begin position="2506"/>
            <end position="2582"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="9">
        <location>
            <begin position="4218"/>
            <end position="4295"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="4790"/>
            <end position="4820"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="7">
        <location>
            <position position="1462"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="7">
        <location>
            <position position="2543"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="7">
        <location>
            <position position="4256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN57449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="5267" mass="563117" checksum="83F3D5927F8598B4" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG70</accession>
    <name>A0A0S2DG70_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1944</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57295">
        <property type="protein sequence ID" value="ALN57295"/>
        <property type="gene ID" value="GLE_1944"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1944"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1909"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="192" mass="20594" checksum="70BB8EFDB0754D5B" modified="2016-02-17" version="1">MAARRSAPGYDGAAARPRRNGSEASMRSDLPMLVCKVNQPDGPVAYVTLTPQQDLSTRGIAPQEIVGQIIDPERPGIEPDNFARNRVFVEFLNGVIARHAPSLPALQAEAQRQGEGIVAIVDGRAETPQDAVPPEDILGAFQVAEGRIVADSYRPNPNHRILGARGFFQLDPQLQRLLLEELAASVGEGTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGD1</accession>
    <name>A0A0S2DGD1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Triosephosphate isomerase</fullName>
            <shortName evidence="4">TIM</shortName>
            <shortName evidence="4">TPI</shortName>
            <ecNumber evidence="4 5">5.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Triose-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">tpiA</name>
        <name evidence="7" type="ORF">BV903_08590</name>
        <name evidence="8" type="ORF">FE772_10880</name>
        <name evidence="6" type="ORF">GLE_2157</name>
    </gene>
    <organism evidence="6 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">C3</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">B25</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18585"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="5.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 5">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 5">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="4 5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000018">
        <property type="protein sequence ID" value="OPD64353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947324.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2157"/>
    <dbReference type="EnsemblBacteria" id="ALN57507">
        <property type="protein sequence ID" value="ALN57507"/>
        <property type="gene ID" value="GLE_2157"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64353">
        <property type="protein sequence ID" value="OPD64353"/>
        <property type="gene ID" value="BV903_08590"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2157"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2120"/>
    <dbReference type="OMA" id="QEVCGAI"/>
    <dbReference type="OrthoDB" id="1266295at2"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00189"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00147_B">
        <property type="entry name" value="TIM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022896">
        <property type="entry name" value="TrioseP_Isoase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020861">
        <property type="entry name" value="Triosephosphate_isomerase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="PTHR21139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="SSF51351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00419">
        <property type="entry name" value="tim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00171">
        <property type="entry name" value="TIM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 4 5" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="2 4 5" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="3 4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="9"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="232"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="active site" description="Electrophile" evidence="4">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD64353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW26101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="250" mass="26395" checksum="9C8BD477C54F2076" modified="2016-02-17" version="1">MRRRIVAGNWKLHGSREFAFALLDEIAAQTPPPGVERVILPPLPYLGELVEHYGERGLGFGAQDVSSNVKGAYTGEVSAAMLKEVGAVYGLVGHSERRQYHRESSELVARKFAAARDAGLVPILCVGETLEEREDGKTQWRLQEQLAPVLELLGVAALDGAVVAYEPVWAIGTGRTATPEQAQEVHAFIRSEIAAQDARIAGSLPILYGGSVKADNAAALFSQPDVDGGLVGGASLVASDFNAIAAAAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGD4</accession>
    <name>A0A0S2DGD4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ferric uptake regulation protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">fur</name>
        <name evidence="5" type="ORF">BV903_23065</name>
        <name evidence="6" type="ORF">FE772_11230</name>
        <name evidence="4" type="ORF">GLE_2228</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">C3</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">YC36</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the Fur family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000078">
        <property type="protein sequence ID" value="OPD61545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947380.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000078.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2228"/>
    <dbReference type="EnsemblBacteria" id="ALN57577">
        <property type="protein sequence ID" value="ALN57577"/>
        <property type="gene ID" value="GLE_2228"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61545">
        <property type="protein sequence ID" value="OPD61545"/>
        <property type="gene ID" value="BV903_23065"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2228"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2193"/>
    <dbReference type="OMA" id="YLYGVCT"/>
    <dbReference type="OrthoDB" id="1630127at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07153">
        <property type="entry name" value="Fur_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002481">
        <property type="entry name" value="FUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043135">
        <property type="entry name" value="Fur_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33202">
        <property type="entry name" value="PTHR33202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01475">
        <property type="entry name" value="FUR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2 3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD61545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW26157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="133" mass="15437" checksum="E2377A51BA6CB208" modified="2016-02-17" version="1">MESQDLRNAGLKVTHPRMRILELLESAKPRHMTAEDIYRMLLEKGEDIGLATVYRVLTQFESAGLVLKHNFEAGQSVYELDRGHHHDHMVDIDSGKIIEFESSEIEELQRKIAAEHGYLIEEHSLVLYVRKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH00</accession>
    <name>A0A0S2DH00_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_11630</name>
        <name evidence="1" type="ORF">GLE_2318</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947446.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57667">
        <property type="protein sequence ID" value="ALN57667"/>
        <property type="gene ID" value="GLE_2318"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2318"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2283"/>
    <dbReference type="OrthoDB" id="2063392at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="122" mass="13918" checksum="643FE85055F294DC" modified="2016-02-17" version="1">MPSPAGLPELIRVDFDLWTLRAQLWFPPEPAPVYVRFTGVRGFRALDEGDLLEFWAPRRRVPGWLWEIDAGGWFQQESQREGFVSGLSGDCREFLLLGQDWCLSVLCLDRPELGPQVELADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH17</accession>
    <name>A0A0S2DH17_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TauD/TfdA family dioxygenase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Taurine catabolism dioxygenase TauD/TfdA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_12825</name>
        <name evidence="3" type="ORF">GLE_2556</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2556"/>
    <dbReference type="EnsemblBacteria" id="ALN57905">
        <property type="protein sequence ID" value="ALN57905"/>
        <property type="gene ID" value="GLE_2556"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2556"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2516"/>
    <dbReference type="OMA" id="HNEQAYT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD" evidence="2">
        <location>
            <begin position="59"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="353" mass="39413" checksum="FFE9139071FCD388" modified="2016-02-17" version="1">MLDFAPLDDSALAAATADLSSLRVRAFDPARGGFPLLVEPATAGAAIADSAHDIAQLNSRLLYRHAGLLFRGFDVAGLESFDAFVRGFGFAPISYEFGSSQRSKLTKGVYTSTEFPKNRSIPLHNEQAYTTAWPMKIWLHCVVASPVGGETPIADSRRIHQRIEPAIRERFERKRLLYVRNYGTGMDLSWQQTFGTESREEVDAFCRDNGIATHWIGDKQLRTEQLVQGTAWHPVTRVPLWFNQAHLFHASSQGAEVMAMLLDVLGDARNLPRHVFYGDGSELEDSVLESIRGVLAEEAVKFPWQPGDIVMLDNMLAAHGREPFDGERKVVVSMAEPFSLQELERLERERLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH38</accession>
    <name>A0A0S2DH38_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid adenylation domain protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Non-ribosomal peptide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FE772_12855</name>
        <name evidence="6" type="ORF">GLE_2560</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947637.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2560"/>
    <dbReference type="EnsemblBacteria" id="ALN57909">
        <property type="protein sequence ID" value="ALN57909"/>
        <property type="gene ID" value="GLE_2560"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2560"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2520"/>
    <dbReference type="OMA" id="LVYNEMA"/>
    <dbReference type="OrthoDB" id="572620at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043604">
        <property type="term" value="P:amide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010060">
        <property type="entry name" value="NRPS_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020802">
        <property type="entry name" value="PKS_thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00824">
        <property type="entry name" value="PKS_TE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01720">
        <property type="entry name" value="NRPS-para261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="1003"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="2497"/>
            <end position="2572"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1038"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="2532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN57909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW26422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="2858" mass="310644" checksum="85DAD6DD59ED972C" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHW4</accession>
    <name>A0A0S2DHW4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, TetR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_2887</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2887"/>
    <dbReference type="EnsemblBacteria" id="ALN58235">
        <property type="protein sequence ID" value="ALN58235"/>
        <property type="gene ID" value="GLE_2887"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2887"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2849"/>
    <dbReference type="OMA" id="MAVQATN"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="3">
        <location>
            <begin position="49"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="239" mass="25085" checksum="3D601AFD7DA5C20A" modified="2016-02-17" version="1">MKFGVAHPEPPGGTGLPAAAPEPALGENAEAATDAAAAKPRRPRGRPRGFDRDQALETAMRMFWQRGFEATSMSELTAAIGVAAPSLYAAFGSKEDLFRAALQRYLEQFRRGHGSVLATPGLAAREAFARLFDALAEGFAACPTRSGCMLVAAETGGLGDATQLREELGAHRASVEAGFRARIERGQVEGDVPADADAAALAKFLSTVVQGLSIQARDGAGAAQLREVLRIALRAWPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI31</accession>
    <name>A0A0S2DI31_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Serine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Seryl-tRNA synthetase</fullName>
            <shortName evidence="8">SerRS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Seryl-tRNA(Ser/Sec) synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">serS</name>
        <name evidence="12" type="ORF">FE772_14895</name>
        <name evidence="11" type="ORF">GLE_2978</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl-tRNA(Sec)</text>
            <dbReference type="Rhea" id="RHEA:42580"/>
            <dbReference type="Rhea" id="RHEA-COMP:9742"/>
            <dbReference type="Rhea" id="RHEA-COMP:10128"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl-tRNA(Ser)</text>
            <dbReference type="Rhea" id="RHEA:12292"/>
            <dbReference type="Rhea" id="RHEA-COMP:9669"/>
            <dbReference type="Rhea" id="RHEA-COMP:9703"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer. The tRNA molecule binds across the dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947953.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2978"/>
    <dbReference type="EnsemblBacteria" id="ALN58326">
        <property type="protein sequence ID" value="ALN58326"/>
        <property type="gene ID" value="GLE_2978"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2978"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2939"/>
    <dbReference type="OMA" id="SPCFRRE"/>
    <dbReference type="OrthoDB" id="353391at2"/>
    <dbReference type="UniPathway" id="UPA00906">
        <property type="reaction ID" value="UER00895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016260">
        <property type="term" value="P:selenocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097056">
        <property type="term" value="P:selenocysteinyl-tRNA(Sec) biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00770">
        <property type="entry name" value="SerRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00176">
        <property type="entry name" value="Ser_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015866">
        <property type="entry name" value="Ser-tRNA-synth_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033729">
        <property type="entry name" value="SerRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43697">
        <property type="entry name" value="PTHR43697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02403">
        <property type="entry name" value="Seryl_tRNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001529">
        <property type="entry name" value="Ser-tRNA-synth_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="10">
        <location>
            <begin position="139"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Serine binding" evidence="8">
        <location>
            <begin position="237"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="268"/>
            <end position="270"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="355"/>
            <end position="358"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="391"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN58326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW26741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="430" mass="47521" checksum="BC4A6A2AC158BBB2" modified="2016-02-17" version="1">MLDPNLLRQQPAEVAARLHATRGFALDADALASLEAERKMVQVRTQELQSQRNKLSGEIGKRKSKGEDVAELMAQVSASGDEQKRGEARLDEIKAEIEAVALAIPNLPHDSVPLGADEAGNVEQHRWGAPREFDFAVKDHVELGARHGWLDAETAAKLSGARFTVLRGGLARLHRALAQFMLDLHVEQHEYQETSVPLLVNADSMRGTGQLPKFEDDLFATVVGEGEAASKRYLIPTSEVPLTNVVRDEIVEDAALPLRMTAHSMCFRAEAGSAGRDTRGMIRQHQFEKVELVAISRPQESYAEHERMTRCAEVVLETLGLPYRRMLLCTGDMGFAAAKTYDLEVWLPSENRYREISSCSNCESFQARRMQARWRNPASGKPEPVHTLNGSGVAIGRAMIAVMENYQNADGSIAVPEALRRYMGGIEVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI78</accession>
    <name>A0A0S2DI78_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome c-type biogenesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ccmF</name>
        <name evidence="11" type="ORF">GLE_2831</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2831"/>
    <dbReference type="EnsemblBacteria" id="ALN58179">
        <property type="protein sequence ID" value="ALN58179"/>
        <property type="gene ID" value="GLE_2831"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2831"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2789"/>
    <dbReference type="OMA" id="SYWGMQL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015232">
        <property type="term" value="F:heme transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032523">
        <property type="entry name" value="CcmF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002541">
        <property type="entry name" value="Cyt_c_assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003567">
        <property type="entry name" value="Cyt_c_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003568">
        <property type="entry name" value="Cyt_c_biogenesis_CcmF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43653">
        <property type="entry name" value="PTHR43653"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16327">
        <property type="entry name" value="CcmF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01578">
        <property type="entry name" value="Cytochrom_C_asm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01410">
        <property type="entry name" value="CCBIOGENESIS"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01411">
        <property type="entry name" value="CCMFBIOGNSIS"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00353">
        <property type="entry name" value="nrfE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="249"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="274"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="352"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="424"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="452"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="491"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="615"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_C_asm" evidence="9">
        <location>
            <begin position="89"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="CcmF_C" evidence="10">
        <location>
            <begin position="315"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="647"/>
            <end position="672"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN58179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="672" mass="72338" checksum="C08053FC78EB3743" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI85</accession>
    <name>A0A0S2DI85_LYSEN</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">D9T17_16270</name>
        <name evidence="1" type="ORF">GLE_2844</name>
    </gene>
    <organism evidence="1 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 4">C3</strain>
        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">B25</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">OH11</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947855.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000040.1"/>
    </dbReference>
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        <property type="gene ID" value="GLE_2844"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD64823"/>
        <property type="gene ID" value="BV903_06365"/>
    </dbReference>
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    <dbReference type="PATRIC" id="fig|69.6.peg.2803"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD64823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ROU05974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <sequence length="100" mass="11047" checksum="1375D20E50A364C3" modified="2016-02-17" version="1">MGNDVTEHAALQELKEGMQYMQQQLQFMAEDLARMKGECSAYREFSMQLIARAPSADSSNALGLVRDPRQLANAPDLLFREGMSQAIAHLAHAVGQQTPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIG2</accession>
    <name>A0A0S2DIG2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">GLE_2943</name>
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    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Xanthomonadaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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            <begin position="319"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="413" mass="45025" checksum="7E91FEAB9FD81E19" modified="2016-02-17" version="1">MLVEVGVADAAAAAEHQQRHRTLDALAGARDRDHHVLDAAPHPLGQQGFVRPPVLVQRGRLVIGRLALEPGAGAVEVLDFLGDRARREARRRRTRRVGDARAAVGVVQARPAARAVARRIAPVVAALGRRPTAWSRGRLGTGAGARXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAAARPAGARRTPRSRRRKSRRSPRPDARSARPANAANRRETARARANRGAGSAATGAARLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIG6</accession>
    <name>A0A0S2DIG6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4 6">Integration host factor subunit beta</fullName>
            <shortName evidence="4">IHF-beta</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 8" type="primary">ihfB</name>
        <name evidence="4" type="synonym">himD</name>
        <name evidence="10" type="ORF">BV903_02750</name>
        <name evidence="12" type="ORF">D9T17_16680</name>
        <name evidence="11" type="ORF">FE772_14585</name>
        <name evidence="8" type="ORF">GLE_2924</name>
        <name evidence="9" type="ORF">LEN_2106</name>
        <name evidence="13" type="ORF">SAMN05421681_10688</name>
    </gene>
    <organism evidence="8 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 14">C3</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="journal article" date="2016" name="DNA Res." volume="0" first="0" last="0">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer, Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">M497-1</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="3">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">ATCC 29487</strain>
        </source>
    </reference>
    <reference evidence="9 17" key="4">
        <citation type="journal article" date="2017" name="DNA Res." volume="24" first="169" last="177">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
            <dbReference type="PubMed" id="28065880"/>
            <dbReference type="DOI" id=".1093/dnares/dsw055"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 17">M497-1</strain>
        </source>
    </reference>
    <reference evidence="10 16" key="5">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 16">B25</strain>
        </source>
    </reference>
    <reference evidence="12 18" key="6">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 18">OH11</strain>
        </source>
    </reference>
    <reference evidence="11 19" key="7">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 19">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 6">This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 6">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP014940">
        <property type="protein sequence ID" value="BAV97593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000005">
        <property type="protein sequence ID" value="OPD65454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000041">
        <property type="protein sequence ID" value="ROU05813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="FNOG01000006">
        <property type="protein sequence ID" value="SDX54911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947915.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2924"/>
    <dbReference type="EnsemblBacteria" id="ALN58272">
        <property type="protein sequence ID" value="ALN58272"/>
        <property type="gene ID" value="GLE_2924"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAV97593">
        <property type="protein sequence ID" value="BAV97593"/>
        <property type="gene ID" value="LEN_2106"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65454">
        <property type="protein sequence ID" value="OPD65454"/>
        <property type="gene ID" value="BV903_02750"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="SDX54911">
        <property type="protein sequence ID" value="SDX54911"/>
        <property type="gene ID" value="SAMN05421681_10688"/>
    </dbReference>
    <dbReference type="KEGG" id="lem:LEN_2106"/>
    <dbReference type="KEGG" id="lez:GLE_2924"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2886"/>
    <dbReference type="OMA" id="RDRVNIY"/>
    <dbReference type="OrthoDB" id="1847472at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000183696">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000218824">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00381">
        <property type="entry name" value="IHF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020816">
        <property type="entry name" value="Histone-like_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005685">
        <property type="entry name" value="IHF_beta"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00988">
        <property type="entry name" value="hip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00045">
        <property type="entry name" value="HISTONE_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3 4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 6" id="KW-0810">Translation regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="59"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAV97593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD65454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW26697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ROU05813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="SDX54911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000183696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000218824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="100" mass="10943" checksum="F9700FA3B8DFD7C8" modified="2016-02-17" version="1">MTKSELIEILSQRQAHLKGDDVDLAVKALLEMMGGALSAGERIEIRGFGSFSLHYRPPRLGRNPKTGESVALPGKHVPHFKPGKELRERVSGVTPLDEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIW0</accession>
    <name>A0A0S2DIW0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein-methionine-sulfoxide reductase catalytic subunit MsrP</fullName>
            <ecNumber evidence="5">1.8.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">msrP</name>
        <name evidence="8" type="ORF">FE772_14930</name>
        <name evidence="7" type="ORF">GLE_2985</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + H2O + L-methionyl-[protein] = a quinol + L-methionyl-(R)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:51296"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12314"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:45764"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + H2O + L-methionyl-[protein] = a quinol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:51292"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
        <text evidence="5">Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MsrP family.</text>
    </comment>
    <dbReference type="EC" id="1.8.5.-" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947960.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2985"/>
    <dbReference type="EnsemblBacteria" id="ALN58333">
        <property type="protein sequence ID" value="ALN58333"/>
        <property type="gene ID" value="GLE_2985"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2985"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2946"/>
    <dbReference type="OMA" id="WPYTEGL"/>
    <dbReference type="OrthoDB" id="1729032at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016672">
        <property type="term" value="F:oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01206">
        <property type="entry name" value="MsrP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022867">
        <property type="entry name" value="MsrP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="SSF56524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 5" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="4 5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Oxidored_molyb" evidence="6">
        <location>
            <begin position="102"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Molybdopterin binding" evidence="5">
        <location>
            <begin position="83"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Molybdopterin binding" evidence="5">
        <location>
            <begin position="237"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW26747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="323" mass="35591" checksum="1F1D75DA3983E6D2" modified="2016-02-17" version="1">MSLRQAFTLPASQITDEAVYRERRRLLAALAMSPALGLAGCAGAEAPPPSAARPASPEQIKAGLRTNEPLTTYADVTGYNNFYEFGTGKGDPSAAAKTLRLSPWTVAVGGECAKPGKLSLEDLIKGLAPQERVYRLRCVEGWSMVIPWLGVPLADVLKRFEPTAKAKYVAFTTLADRKQMPGIAYPSISWPYREGLRIDEAMHPLTLLATGLYGKPLPQQNGAPLRLVVPWKYGFKSIKSIVAITFVERRPATAWNSLQPDEYGFFSNVNPDVDHPRWSQKTERRIAGTGSKLFAERIPTRLFNGYGEQVASLYAGMNLKTWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIX3</accession>
    <name>A0A0S2DIX3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tetratricopeptide repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_15000</name>
        <name evidence="1" type="ORF">GLE_3001</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947972.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3001"/>
    <dbReference type="EnsemblBacteria" id="ALN58349">
        <property type="protein sequence ID" value="ALN58349"/>
        <property type="gene ID" value="GLE_3001"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3001"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2962"/>
    <dbReference type="OMA" id="RYSQGIS"/>
    <dbReference type="OrthoDB" id="1069317at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="284" mass="30000" checksum="91DD7B3569643EC2" modified="2016-02-17" version="1">MAAKTAWAAFPHDAKAFAYAGDALKKAWPKLHAGDAEPFPDAKRAGALIKAAGKAAPKGVDTDALAETLQEAWRAFHRGDFKAAFDAGEKLGPVGASVAVKALGIHATYLVEDEAEQLKRYQQAAKLAEAAVAALPDEANSHYRYAFALGRYSQGLSIAKALKDGIAGKVRAALDATLEREPKHAEAHTAMALYHAEIIDKIGGMIGGLTYGAKASESEKHIKTALKLTPDSPIAHIEHGNVLMLLHGDKQEDAAAAAYEKAAKLKPADAMETLDAAYAKAQLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ01</accession>
    <name>A0A0S2DJ01_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Export-related chaperone CsaA</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">tRNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">csaA</name>
        <name evidence="7" type="ORF">D9T17_16640</name>
        <name evidence="6" type="ORF">FE772_14545</name>
        <name evidence="5" type="ORF">GLE_2916</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">OH11</strain>
        </source>
    </reference>
    <reference evidence="6 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 10">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000041">
        <property type="protein sequence ID" value="ROU05805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947907.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2916"/>
    <dbReference type="EnsemblBacteria" id="ALN58264">
        <property type="protein sequence ID" value="ALN58264"/>
        <property type="gene ID" value="GLE_2916"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2916"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2878"/>
    <dbReference type="OMA" id="FPEARNP"/>
    <dbReference type="OrthoDB" id="2038415at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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    </dbReference>
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        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
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        <property type="entry name" value="tRNA-bd_dom"/>
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        <property type="entry name" value="PTHR11586:SF37"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="chap_CsaA"/>
        <property type="match status" value="1"/>
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        <location>
            <begin position="19"/>
            <end position="121"/>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW26689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ROU05805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="121" mass="13289" checksum="2F1C476C8D12045D" modified="2016-02-17" version="1">MSENEHGAAPAHEPITWGDFEKVAICAGTVVQVEEFPQARKPAWKLWVDFGPYGVRKTSAQIRQLYSAEELVGRQIVGVINFPPKQIGPFVSEFLLTGFPTDEGVVVTAIERPVPNGTRLA</sequence>
</entry>
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        <submittedName>
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        </submittedName>
    </protein>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
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    <dbReference type="EnsemblBacteria" id="ALN58239">
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            <end position="518"/>
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        <location>
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            <end position="712"/>
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            <end position="890"/>
        </location>
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    <evidence type="ECO:0000259" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
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    </evidence>
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            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="903" mass="100380" checksum="F815CF002120E7B5" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJN2</accession>
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            <fullName evidence="2">Uncharacterized protein</fullName>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="172" mass="18302" checksum="EA601B5C3959DA77" modified="2016-02-17" version="1">MSVTVWGLLCPLLFVAGLVALARTIGSLLRLLDRALVARVPARSGERLSVPAGRYDLCIEGRTLSPDFLGVHYALHEAAGGEPIAVHRKYLSRTKVSGLGSTRISTGWFELARDSELSLSVDGMSPQAQQRAWIVVQRPVGAGIALRVVLLVLAGFATIGGLVGSVHAWLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJY0</accession>
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            <fullName evidence="1">Uncharacterized protein</fullName>
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    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3499"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="134" mass="14902" checksum="10FB9C800DC8BD0D" modified="2016-02-17" version="1">MQFDRIHKHLTQAGFRLSVHDSVICVELSLEQGTRHQSIFLSEQEDDDGRAFLRVSTAIAPTTGLDARRALAFNWESHVGYLAIGNLDGVPYLQLCENRPLETLDAAELQRLVLEIGGVGDRMERVLSADGDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJZ1</accession>
    <name>A0A0S2DJZ1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3473</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948318.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3473"/>
    <dbReference type="EnsemblBacteria" id="ALN58818">
        <property type="protein sequence ID" value="ALN58818"/>
        <property type="gene ID" value="GLE_3473"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3473"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3420"/>
    <dbReference type="OMA" id="WRSTHAN"/>
    <dbReference type="OrthoDB" id="1644255at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="109" mass="11633" checksum="9FA17B7CD45BAB48" modified="2016-02-17" version="1">MSAPALPSPVAEFVAAVNRGDAAAALAFFGRDGVVDDWGTRHVGAAAIAQWSAREFVGARGRLTPTRVGRDGGRIVVDAGWRSDFYSGDSRFVFTVDGARIREMRIVGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK65</accession>
    <name>A0A0S2DK65_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Stringent starvation protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">sspB</name>
        <name evidence="2" type="ORF">GLE_3596</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3596"/>
    <dbReference type="EnsemblBacteria" id="ALN58940">
        <property type="protein sequence ID" value="ALN58940"/>
        <property type="gene ID" value="GLE_3596"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3596"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3540"/>
    <dbReference type="OMA" id="FQARFGG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007481">
        <property type="entry name" value="SspB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036760">
        <property type="entry name" value="SspB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37486">
        <property type="entry name" value="PTHR37486"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04386">
        <property type="entry name" value="SspB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005276">
        <property type="entry name" value="SspB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101738">
        <property type="entry name" value="SSF101738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="164" mass="17393" checksum="2B350399960B8D7F" modified="2016-02-17" version="1">MSESSTSMTSHRPYLLRALYEWIADNGMTPHLLVDATRPAVQVPAHAVKEGKIVLNVAARAVSHLEMGNDFIRFSARFGGVSHPVNVPVGAVLAIYARETGQGMALPEDASLEDAALDEASSEQPESAAPSPQLSAVPSDPPDGDDDGPHTPTPRRGGHLRIVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK72</accession>
    <name>A0A0S2DK72_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59014">
        <property type="protein sequence ID" value="ALN59014"/>
        <property type="gene ID" value="GLE_3670"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3670"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="54" mass="5664" checksum="9708D60C9C538B2B" modified="2016-02-17" version="1">MSELVRAGVRGLVRQASRAAAGQDAQKRKREVSGQGSQAHAASFRVAKRVMAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK85</accession>
    <name>A0A0S2DK85_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metallo-beta-lactamase domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3612</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948416.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3612"/>
    <dbReference type="EnsemblBacteria" id="ALN58956">
        <property type="protein sequence ID" value="ALN58956"/>
        <property type="gene ID" value="GLE_3612"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3612"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3556"/>
    <dbReference type="OMA" id="YQNLVFP"/>
    <dbReference type="OrthoDB" id="1815576at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="33"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="290" mass="32107" checksum="37F6D8B4822B9075" modified="2016-02-17" version="1">MSGEVALTLAASGHSCADPRHLGLAAGARMRFPAGWALIEHPVQGAILFDCGYGPDAREAMRAGLRWVYRRAIHACCPPHADAAHLLRQRGLDADDVRLLVISHFHPDHIGGLGEFRNARFVAHAQGWRRIGQAGWLELLHAQIWKELLPADFAERLQLLDEDGRRPLAADLAGLGEGWDLFGDGSLHALSLPGHARGQIGLALRTRDGERVVLAADAFWRREQLDRPQALPWLTQLLAMDDAGAYLDTLRRLARFRDTHHGAWVIPSHCADTLAQWRERHPQSVLDAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKA8</accession>
    <name>A0A0S2DKA8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Exopolysaccharide biosynthesis protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Exopolysaccharide synthesis, ExoD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_17245</name>
        <name evidence="3" type="ORF">GLE_3504</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3504"/>
    <dbReference type="EnsemblBacteria" id="ALN58849">
        <property type="protein sequence ID" value="ALN58849"/>
        <property type="gene ID" value="GLE_3504"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3504"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3448"/>
    <dbReference type="OMA" id="FGLKPWL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010331">
        <property type="entry name" value="ExoD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41795">
        <property type="entry name" value="PTHR41795"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06055">
        <property type="entry name" value="ExoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033239">
        <property type="entry name" value="ExoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="73"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="195"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="232" mass="24162" checksum="4CAD53404EF0981D" modified="2016-02-17" version="1">MTPPAADRDPPGRGDGGARRRAGAGAAHEAGTRALLDAIAAGDPDEAVKFGDVFNGLGNRSFGMLLFVSTLPAFIPIPGVGGAVSGPLVILVGLQLLIGLRKPWLPGFIARRGPHRSALGKFRNLLAPWLTRLERFVSPRLPAVLDHRAASACTGLLLVLVGVLLSLPIPFTNFLFGALLLLFAFALLERDGKLMLIAWAAGAAAVVVFGILSGSLVQAVAEWIALARGKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKI4</accession>
    <name>A0A0S2DKI4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_3533</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="2.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3533"/>
    <dbReference type="EnsemblBacteria" id="ALN58877">
        <property type="protein sequence ID" value="ALN58877"/>
        <property type="gene ID" value="GLE_3533"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3533"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3477"/>
    <dbReference type="OMA" id="RCADIFA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031167">
        <property type="term" value="P:rRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004398">
        <property type="entry name" value="RNA_MeTrfase_RsmD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00095">
        <property type="entry name" value="TIGR00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="223" mass="23124" checksum="6B96BEC9AB560954" modified="2016-02-17" version="1">MNMSKRGRSGARSPGRSDAAQSKAGGAPARGQPGKVRIIGGRWRGTRLDVADAPGLRPTSDRVRETLFNWLQPMLSGARVLDLFAGSGALGLEALSRGAAGAVLVERDPALAAQLRALAARLPGGEAAQVVQADALAWLAQQPVAAGAAGEGGAGFDLAFVDPPFAAGLWDAVWPALSPRLAPAAWLYVEAPLAASLALPAPWLPHREGATREVRYALYRRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKI9</accession>
    <name>A0A0S2DKI9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">rpmC</name>
        <name evidence="7" type="ORF">BV903_22995</name>
        <name evidence="9" type="ORF">D9T17_09470</name>
        <name evidence="8" type="ORF">FE772_18610</name>
        <name evidence="6" type="ORF">GLE_3782</name>
    </gene>
    <organism evidence="6 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 10">C3</strain>
        </source>
    </reference>
    <reference evidence="7 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">OH11</strain>
        </source>
    </reference>
    <reference evidence="8 13" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 13">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000077">
        <property type="protein sequence ID" value="OPD61609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000023">
        <property type="protein sequence ID" value="ROU07189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948548.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3782"/>
    <dbReference type="EnsemblBacteria" id="ALN59126">
        <property type="protein sequence ID" value="ALN59126"/>
        <property type="gene ID" value="GLE_3782"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61609">
        <property type="protein sequence ID" value="OPD61609"/>
        <property type="gene ID" value="BV903_22995"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3782"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3726"/>
    <dbReference type="OMA" id="RFQMATS"/>
    <dbReference type="OrthoDB" id="2063644at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00374">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001854">
        <property type="entry name" value="Ribosomal_L29/L35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_L29/L35_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018254">
        <property type="entry name" value="Ribosomal_L29_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00831">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="SSF46561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00012">
        <property type="entry name" value="L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00579">
        <property type="entry name" value="RIBOSOMAL_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD61609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW27353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROU07189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="61" mass="7108" checksum="38151FA98CF3A975" modified="2016-02-17" version="1">MELKQLREKSADELKAHLVELHKEGFALRMQKATGQLAKTHDARRVRREIARVNMLLGEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKJ3</accession>
    <name>A0A0S2DKJ3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type IV pilus assembly protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Type IV pilus modification protein PilV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pilV</name>
        <name evidence="3" type="ORF">FE772_17840</name>
        <name evidence="2" type="ORF">GLE_3625</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3625"/>
    <dbReference type="EnsemblBacteria" id="ALN58969">
        <property type="protein sequence ID" value="ALN58969"/>
        <property type="gene ID" value="GLE_3625"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3625"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3569"/>
    <dbReference type="OMA" id="NVARWQC"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013362">
        <property type="entry name" value="Pilus_4_PilV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07963">
        <property type="entry name" value="N_methyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02523">
        <property type="entry name" value="type_IV_pilV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00409">
        <property type="entry name" value="PROKAR_NTER_METHYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="174" mass="18542" checksum="99A9630CB67DB78D" modified="2016-02-17" version="1">MSLIVNRISARAAPRRSLPGARSRQRGFSLIEVLIAMLVIGFGLLGLAMMQTLSVRYSQSANYRTQAFNLAYDLFDQIRANRALSAQFTKIDEGSFSGVTGKNCSRATSGFVGPAESATRWKCQVRSTLGAGAFAQVTQDGARTTVTISWSDARAAVGAVGNNANGRITVSSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKP0</accession>
    <name>A0A0S2DKP0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rpsS</name>
        <name evidence="8" type="ORF">BV903_23015</name>
        <name evidence="10" type="ORF">D9T17_09450</name>
        <name evidence="9" type="ORF">FE772_18630</name>
        <name evidence="7" type="ORF">GLE_3786</name>
    </gene>
    <organism evidence="7 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 11">C3</strain>
        </source>
    </reference>
    <reference evidence="8 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">OH11</strain>
        </source>
    </reference>
    <reference evidence="9 14" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000077">
        <property type="protein sequence ID" value="OPD61613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000023">
        <property type="protein sequence ID" value="ROU07186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <source>
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</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Fernandez C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        <source>
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        <source>
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    <sequence length="117" mass="13068" checksum="89F80962C4724C38" modified="2016-02-17" version="1">MPADRLSALVYPVLLLLGSNIFMTFAWYGHLKYKSAPLTVAIGVSWGIALFEYCLQVPANRLGSAVYSAPQLKGMQEVITLLVFACFSIWYLGQPLKWNHWAGFGLIVVAAWLIFLE</sequence>
</entry>
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    <accession>A0A0S2DL84</accession>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    </dbReference>
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        <location>
            <begin position="2940"/>
            <end position="3042"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="3042" mass="307142" checksum="53F493F698C3A242" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL85</accession>
    <name>A0A0S2DL85_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tol-Pal system protein TolQ</fullName>
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    <gene>
        <name evidence="8 10" type="primary">tolQ</name>
        <name evidence="11" type="ORF">BV903_01165</name>
        <name evidence="13" type="ORF">D9T17_08405</name>
        <name evidence="12" type="ORF">FE772_19915</name>
        <name evidence="10" type="ORF">GLE_4056</name>
    </gene>
    <organism evidence="10 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
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    <reference evidence="10 14" key="1">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 14">C3</strain>
        </source>
    </reference>
    <reference evidence="11 15" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 15">B25</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">OH11</strain>
        </source>
    </reference>
    <reference evidence="12 17" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ExbB/TolQ family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000002">
        <property type="protein sequence ID" value="OPD65890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000021">
        <property type="protein sequence ID" value="ROU07545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948748.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4056"/>
    <dbReference type="EnsemblBacteria" id="ALN59398">
        <property type="protein sequence ID" value="ALN59398"/>
        <property type="gene ID" value="GLE_4056"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65890">
        <property type="protein sequence ID" value="OPD65890"/>
        <property type="gene ID" value="BV903_01165"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4056"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3999"/>
    <dbReference type="OMA" id="SWTYIFR"/>
    <dbReference type="OrthoDB" id="1796180at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043213">
        <property type="term" value="P:bacteriocin transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02202">
        <property type="entry name" value="TolQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014163">
        <property type="entry name" value="Tol-Pal_TolQ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02796">
        <property type="entry name" value="tolQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="4 8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="9">
        <location>
            <begin position="113"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN59398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OPD65890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW27570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ROU07545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="260" mass="28189" checksum="09AEF4BA37DBC310" modified="2016-02-17" version="1">MTSSLIALLATTVQALPEEATQAVTQGAAAAGQAAAEFSLLDLVIKASLPVQFIMALLVVASLTSWFIIFRKWKVIRRAKAEADHFEERFWSGAELSKLYAGTTERARNIGGLEAIFEAGFREFNRVRQRRGVDARAQIEGAQRAMRATGSREVDGLEHNLELLANIGSTSPYIGLVGTVFGIMVTMHSLVSASKQVGIADVAPGISEALLATAMGLFVAIPAVWAYNRFATGVERLAVRYDAFSEEFSSILQRQAHLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL95</accession>
    <name>A0A0S2DL95_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyrroloquinoline-quinone synthase</fullName>
            <ecNumber evidence="2">1.3.3.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Coenzyme PQQ synthesis protein C</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Pyrroloquinoline quinone biosynthesis protein C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 5" type="primary">pqqC</name>
        <name evidence="6" type="ORF">FE772_18495</name>
        <name evidence="5" type="ORF">GLE_3757</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O2 = H(+) + 2 H2O + 2 H2O2 + pyrroloquinoline quinone</text>
            <dbReference type="Rhea" id="RHEA:10692"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:58442"/>
            <dbReference type="ChEBI" id="CHEBI:58778"/>
            <dbReference type="EC" id="1.3.3.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PqqC family.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.11" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3757"/>
    <dbReference type="EnsemblBacteria" id="ALN59101">
        <property type="protein sequence ID" value="ALN59101"/>
        <property type="gene ID" value="GLE_3757"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3757"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3701"/>
    <dbReference type="OMA" id="AYVHFVR"/>
    <dbReference type="UniPathway" id="UPA00539"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033732">
        <property type="term" value="F:pyrroloquinoline-quinone synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006725">
        <property type="term" value="P:cellular aromatic compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018189">
        <property type="term" value="P:pyrroloquinoline quinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00654">
        <property type="entry name" value="PQQ_syn_PqqC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011845">
        <property type="entry name" value="PqqC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039068">
        <property type="entry name" value="PqqC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004305">
        <property type="entry name" value="Thiaminase-2/PQQC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40279">
        <property type="entry name" value="PTHR40279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03070">
        <property type="entry name" value="TENA_THI-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="SSF48613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02111">
        <property type="entry name" value="PQQ_syn_pqqC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 2" id="KW-0884">PQQ biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TENA_THI-4" evidence="4">
        <location>
            <begin position="33"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW27331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="267" mass="29946" checksum="1F64F67E40577CA8" modified="2016-02-17" version="1">MNAATAPDARAAQAERAPRIDADAPLSPDELEARLRAIGAERYHDKHPFHILLHGGRLGRAQVQAWALNRFEYQRCIPLKDAALLARIEDPQLRRVWRQRIVDHDGEREGEGGIARWLRLTDALGLDRELVESGRALLPATRFAVQAYLQFVRERSLLEAIASSLTELFAPAIIGQRVAGMLANYDFVSRDALAYFDSRLQQASQDADFALDYVKRHAATRAQQESVLAALRFKCDVLWSMLDALHLAYVEPRLVPPGAFHPGQARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLA4</accession>
    <name>A0A0S2DLA4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fasciclin</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Fasciclin domain protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Fasciclin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_00685</name>
        <name evidence="4" type="ORF">FE772_19745</name>
        <name evidence="2" type="ORF">GLE_4028</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000002">
        <property type="protein sequence ID" value="OPD65804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948726.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4028"/>
    <dbReference type="EnsemblBacteria" id="ALN59370">
        <property type="protein sequence ID" value="ALN59370"/>
        <property type="gene ID" value="GLE_4028"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65804">
        <property type="protein sequence ID" value="OPD65804"/>
        <property type="gene ID" value="BV903_00685"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4028"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3967"/>
    <dbReference type="OMA" id="YPSKNIV"/>
    <dbReference type="OrthoDB" id="1776069at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="SSF82153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAS1" evidence="1">
        <location>
            <begin position="11"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD65804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="153" mass="16281" checksum="D225D9FC8087A9BF" modified="2016-02-17" version="1">MNANQDSSRPALNLADTAATNGTFNIFLQAVDKAGLKEVLSGVGPHTVLAPTDAAFDKLPVGRLDELYQPDNQAELADIINYHVIRGRRTSSELGKWSTARTAHGQEAPISRDGGKVTIDGANITMQDMDSTNGILHGIDKVNIPDSKSNASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLB3</accession>
    <name>A0A0S2DLB3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_20305</name>
        <name evidence="1" type="ORF">GLE_4141</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948819.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59483">
        <property type="protein sequence ID" value="ALN59483"/>
        <property type="gene ID" value="GLE_4141"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4141"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4083"/>
    <dbReference type="OrthoDB" id="1947830at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="114" mass="13015" checksum="7CD192262AC91FB5" modified="2016-02-17" version="1">MSDPVDPEDHYPLYPRGMLRRHGLLDAHDLADYLPDWSETQLREDFKRGLDAIGDSAEFVLEQNLGLDGGETVLRVHGLPLLLSDDIWNFQVLAPPELLRPLAEAMRALRKRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLI8</accession>
    <name>A0A0S2DLI8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4124</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4124"/>
    <dbReference type="EnsemblBacteria" id="ALN59466">
        <property type="protein sequence ID" value="ALN59466"/>
        <property type="gene ID" value="GLE_4124"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4124"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4066"/>
    <dbReference type="OMA" id="PIKRALW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007922">
        <property type="entry name" value="DUF721/UPF0232"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05258">
        <property type="entry name" value="DciA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="126" mass="13512" checksum="A733882ADB7792A1" modified="2016-02-17" version="1">MEDTAGNPIKRALWLDDLDLRLRPYLPPSLAAHARLANFERGRLVYVVDAPVWRAKLRLAAPEMLDAARSVGLKAAELVVKTTIPQPAAAPVRQAKPLSAATQKALQAALDSLRGPDGSKGRGDAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLU2</accession>
    <name>A0A0S2DLU2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RDD family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_4190</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4190"/>
    <dbReference type="EnsemblBacteria" id="ALN59532">
        <property type="protein sequence ID" value="ALN59532"/>
        <property type="gene ID" value="GLE_4190"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4190"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4132"/>
    <dbReference type="OMA" id="GIYATVS"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010432">
        <property type="entry name" value="RDD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06271">
        <property type="entry name" value="RDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="RDD" evidence="6">
        <location>
            <begin position="42"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="186" mass="20809" checksum="9562C7603A898851" modified="2016-02-17" version="1">MSESGKQAFAAFAHSSLLHARSCLYPAAMTQPAAAAPDRPAALIGWRLLSLFYDFWPVLALWMLIGAVMVAAFTVAGHDTHENIRPLTAWWFLEWALCWLAAGGYATLSWRRGGQTLGMRPWRLRVGAAEGGVPGWKALWLRYAVGTLSLALGGLGFWWAWFDRDRLTWHDRASGTRTSRLPKRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLW4</accession>
    <name>A0A0S2DLW4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription antitermination protein NusB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Antitermination factor NusB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">nusB</name>
        <name evidence="9" type="ORF">BV903_07690</name>
        <name evidence="10" type="ORF">FE772_20350</name>
        <name evidence="8" type="ORF">GLE_4150</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the NusB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000015">
        <property type="protein sequence ID" value="OPD64534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948826.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4150"/>
    <dbReference type="EnsemblBacteria" id="ALN59492">
        <property type="protein sequence ID" value="ALN59492"/>
        <property type="gene ID" value="GLE_4150"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64534">
        <property type="protein sequence ID" value="OPD64534"/>
        <property type="gene ID" value="BV903_07690"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4150"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4092"/>
    <dbReference type="OMA" id="DRMPVVD"/>
    <dbReference type="OrthoDB" id="1574817at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00073">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035926">
        <property type="entry name" value="NusB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011605">
        <property type="entry name" value="NusB_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006027">
        <property type="entry name" value="NusB_RsmB_TIM44"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11078">
        <property type="entry name" value="PTHR11078"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01029">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48013">
        <property type="entry name" value="SSF48013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01951">
        <property type="entry name" value="nusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="4 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NusB" evidence="7">
        <location>
            <begin position="16"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD64534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW27639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="155" mass="17591" checksum="AA9BFA3340369595" modified="2016-02-17" version="1">MNRRRPDGIDPVARSRARRRALQAIYAWQMTGTRADEVIAQFAHEQAHEVADLAYFEDLVRGVARHQEDDLDPALAPFLDREIEQVDPIERAGLRIAAYELRHRLDVPYRVVINEAIESVKRFGAEHGHTYVNGVLDRAAAQWRAAEAAAAAKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLX6</accession>
    <name>A0A0S2DLX6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tryptophan--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Tryptophanyl-tRNA synthetase</fullName>
            <shortName evidence="8">TrpRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">trpS</name>
        <name evidence="12" type="ORF">FE772_21160</name>
        <name evidence="11" type="ORF">GLE_4329</name>
    </gene>
    <organism evidence="11 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 13">C3</strain>
        </source>
    </reference>
    <reference evidence="12 14" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of tryptophan to tRNA(Trp).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + H(+) + L-tryptophanyl-tRNA(Trp)</text>
            <dbReference type="Rhea" id="RHEA:24080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9671"/>
            <dbReference type="Rhea" id="RHEA-COMP:9705"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78535"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948965.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4329"/>
    <dbReference type="EnsemblBacteria" id="ALN59670">
        <property type="protein sequence ID" value="ALN59670"/>
        <property type="gene ID" value="GLE_4329"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4329"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4268"/>
    <dbReference type="OMA" id="LGHYFGT"/>
    <dbReference type="OrthoDB" id="951354at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00806">
        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00140_B">
        <property type="entry name" value="Trp_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024109">
        <property type="entry name" value="Trp-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036913">
        <property type="entry name" value="YegP-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160113">
        <property type="entry name" value="SSF160113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="415"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="12"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="202"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="11"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="19"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>L-tryptophan</name>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="156"/>
            <end position="158"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="202"/>
            <end position="206"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN59670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW27781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="450" mass="49493" checksum="D7E5ADB72A8E1D47" modified="2016-02-17" version="1">MTQTRVLTGITTSGTPHLGNYVGAIRPAVAASRDPGVESFYFLADLHALIKVQKPERVQRSTLEIAASWLACGLEPDKVWFYRQSEIVEIPELAWFLTCVAGKGILNRAHAYKAAVDKNRLDGEDDDASITAGLFMYPVLMAADILVFNAHKVPVGRDQIQHIEMARDFGQRFNHLYGEHFVLPEALIEESVATLPGLDGRKMSKSYDNTIPLFAPREELKKLIYSIVTDSRAPGEPKQTEGSALFQIYQAFASEEETEAMRRAFAEGIAWGEAKQALFERIDAEIAPLREKYEALMARPQDIEALLIDGARRVRERYGKANMQRLREAVGLRDLSDAGGLSLAEETRAAAVAAFKQYREADGRFYFKLAVGDEVLLQSRGFAAPKDIGQLIGRAKSEDSDALLDALLAASEPVAADARARVAQALQAIREAEEAARQAKAAAAQERAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMD8</accession>
    <name>A0A0S2DMD8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-oxoacyl-ACP reductase FabG</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Oxidoreductase, short chain dehydrogenase/reductase family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_22075</name>
        <name evidence="1" type="ORF">GLE_4521</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949118.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4521"/>
    <dbReference type="EnsemblBacteria" id="ALN59862">
        <property type="protein sequence ID" value="ALN59862"/>
        <property type="gene ID" value="GLE_4521"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4521"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4457"/>
    <dbReference type="OMA" id="SWKDEIM"/>
    <dbReference type="OrthoDB" id="1356861at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="247" mass="24931" checksum="05240E6379C1D82C" modified="2016-02-17" version="1">MTLPLAGKVALVTGASRGIGAAIARRLAADGADVAITYVSSAQRAENLAAQIRADGRRAIAIAADSADAQAVTAAVERTVAELGGLDILVNNAGVWTYGPFEDESLENYERVMAIHVRAPFVAAQAASKHLPRGGRIVTIGSCLGERVGAPGMALYSLSKAAVVGLSKGLAQDLGPRGITVNTVQPGPIDTDMNPADGEGADHQRAGLPLRAFGNADDIAATVAHLAGPGGAFITGTQISVDGGFSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DME8</accession>
    <name>A0A0S2DME8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">BV903_23200</name>
        <name evidence="11" type="ORF">FE772_21230</name>
        <name evidence="9" type="ORF">GLE_4341</name>
    </gene>
    <organism evidence="9 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">C3</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">B25</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000079">
        <property type="protein sequence ID" value="OPD61529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948977.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000079.1"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN59682">
        <property type="protein sequence ID" value="ALN59682"/>
        <property type="gene ID" value="GLE_4341"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD61529"/>
        <property type="gene ID" value="BV903_23200"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4341"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4280"/>
    <dbReference type="OMA" id="FFVYDVE"/>
    <dbReference type="OrthoDB" id="692375at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
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    </dbReference>
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        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
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        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
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    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="198"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="257"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN59682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD61529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW27790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="468" mass="51568" checksum="3A6377BED5713EB4" modified="2016-02-17" version="1">MSWGQPRSLRARQLLAASLGLLAFLALAGVALDRAFLETAENNLRQRLTSYALAYAADTDFGRGGEIIPPYDPPDPRFDRPGSGLYAEVILPNDHWDSVSAQGPVLPNGGMLKPAEESFEGPLPLTEINGKPGEAYRYGRGLIWSVDGDPRSEFQYTILILEDTSALRHQVGVFRQALWRYLGGAGVILLLLQALIMQWSLRPLKRVIEELKRVQRGMASRMSERHPRELEPLTESINAFIESERENLDRQRNTLADLAHSLKTPLAVLRARLDDDSGAQMDKELREDLDLQLRRMNELVSYQLARAASGGHALFAAPIAIEPHAEEIVRGLEKVYASKGILCEFDLADGVQFHGEPGDLQELLGNLLENAFKWANSRVLLTVKPGETAAQRRPGLLLAVDDDGPGIPAEKVAKILQRGVRGDERVHGHGIGLAIVQDLVRGYRGTLDVTASEELGGTRFEVKLPPGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMM1</accession>
    <name>A0A0S2DMM1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_13975</name>
        <name evidence="1" type="ORF">GLE_4569</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59910">
        <property type="protein sequence ID" value="ALN59910"/>
        <property type="gene ID" value="GLE_4569"/>
    </dbReference>
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        <property type="gene ID" value="BV903_13975"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4569"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4505"/>
    <dbReference type="OrthoDB" id="1970351at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD63241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="72" mass="7957" checksum="7382E366B0AAA863" modified="2016-02-17" version="1">MFRVELKQRDGGDDRALTAAVAEIEQEYRSAEAALKSVLPSARKYALQAGKGLWLRVFYNGDSQPVFGTLVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMW6</accession>
    <name>A0A0S2DMW6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4577</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59918">
        <property type="protein sequence ID" value="ALN59918"/>
        <property type="gene ID" value="GLE_4577"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4577"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4514"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="100" mass="12092" checksum="2088C831AECA7C60" modified="2016-02-17" version="1">MSDEAIYENALAGYLVAKEQQARLRTWHDDEIVAFARYFLEKRPEEYAEFLRQEKEFNEIEPDLALAVRHLIWQWMPDLDFPDCDELFGKFRDYVKSDRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNK4</accession>
    <name>A0A0S2DNK4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cupin</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Cupin domain-containing protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Cupin superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_10450</name>
        <name evidence="4" type="ORF">FE772_23420</name>
        <name evidence="2" type="ORF">GLE_4821</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000023">
        <property type="protein sequence ID" value="OPD64001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949337.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4821"/>
    <dbReference type="EnsemblBacteria" id="ALN60162">
        <property type="protein sequence ID" value="ALN60162"/>
        <property type="gene ID" value="GLE_4821"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64001">
        <property type="protein sequence ID" value="OPD64001"/>
        <property type="gene ID" value="BV903_10450"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4821"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4752"/>
    <dbReference type="OMA" id="ICTPRFT"/>
    <dbReference type="OrthoDB" id="1928636at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="40"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="126" mass="14014" checksum="7B5F2457C5CE5B3C" modified="2016-02-17" version="1">MTEPRIVRRDEPTEFYLSERCHVVEHWNSPDDAQASIARIRVAPGTTTQLHRLRGTAERYLIHTGRGRIEVEGLAPAEVGPGDTVFIPAGAAQRIANLGDDDLMFLAICTPRFVPECYENLESPDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNS2</accession>
    <name>A0A0S2DNS2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Amidohydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Amidohydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_23345</name>
        <name evidence="4" type="ORF">GLE_4803</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4803"/>
    <dbReference type="EnsemblBacteria" id="ALN60144">
        <property type="protein sequence ID" value="ALN60144"/>
        <property type="gene ID" value="GLE_4803"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4803"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4735"/>
    <dbReference type="OMA" id="HCTEGHK"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726737" evidence="2">
        <location>
            <begin position="21"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro_3" evidence="3">
        <location>
            <begin position="390"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="453"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW28148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="482" mass="51137" checksum="1B8070BEF598098F" modified="2016-02-17" version="1">MFRPFLAGCGLVLLAGAVQAAPAPASRYTQDPYPSTYKPVASGPVLLQGATVLTGTGQRLDGADVLLRDGKIVAVGSRLDAPGDATRVDASGKWITPGIIDVHSHLGVYPSPGVGAHSDGNEMTSPVTPNVWAEHSIWPQDPGFASALAGGITSLQILPGSANLIGGRGVTLKNVPAGSYQAMKFPGAPWGLKMACGENPKRVYGSRNVSPGTRMGNVAGYRAAFIDASEYLRKTTPKAAKPAKKRWWQSSGAPAASDSEKDTGGKRDLKLDTLAGAIKGDILVHIHCYRADEMTTMLDLAKEFGFKVSAFHHGVEAYKIADRLAAENVCGALWADWWGFKMEAFDGIQENIAIVDRPANSCAIVHSDSEEGIQRLNQEAAKVIAHARLAGIEIAPERAIRWLTQNPAKALGIGERTGTLEAGKMGDVVVWNGNPFSVYAKTEQVYIDGARVYDRNDPSRQPKSDFMLGQPAAQGAAAGDVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNW7</accession>
    <name>A0A0S2DNW7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alkaline phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.1</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="4">DNRLRE domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">phoA</name>
        <name evidence="4" type="ORF">FE772_24575</name>
        <name evidence="3" type="ORF">GLE_5070</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.3.1" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949530.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60411">
        <property type="protein sequence ID" value="ALN60411"/>
        <property type="gene ID" value="GLE_5070"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5070"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4997"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039331">
        <property type="entry name" value="PPA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22953">
        <property type="entry name" value="PTHR22953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242213" evidence="1">
        <location>
            <begin position="30"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="2">
        <location>
            <begin position="176"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="581" mass="60668" checksum="466D7169BD1BC462" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP17</accession>
    <name>A0A0S2DP17_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ntrB</name>
        <name evidence="6" type="ORF">FE772_24470</name>
        <name evidence="5" type="ORF">GLE_5049</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949515.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5049"/>
    <dbReference type="EnsemblBacteria" id="ALN60390">
        <property type="protein sequence ID" value="ALN60390"/>
        <property type="gene ID" value="GLE_5049"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5049"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4977"/>
    <dbReference type="OMA" id="IEQTAYQ"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="133"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW28333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="353" mass="38220" checksum="C855AD882959FD12" modified="2016-02-17" version="1">MPADPAPSADLSLDALTTPVAWSDAAGSLTGCNLAFSRWFGIGVRRLLGWPLAGLDADGRLALAVARAGGDEAPLRMRRMRLRYADGEERFADLWLSRRDDGGWLLEAHPVDEFPGDDPALLLPSALSASLKGLAHELRNPLAGLKGASQLLARRIDDRDARELIELIDSEVERLTGLVDRLLTPAPPRPHAPLNIHAVLERVLRLAEADAGWAVRLVRDYDPSLPEFAGDADRLMQAVWNLARNAIEAGANHVHLRTRVEHGARVGDSAHPIALRLEIIDDGRGVPDELAEQLFLPLVSGRAEGSGLGLALAQQVAREHRGSLTYRSRPGHTVFTLLLPMHIEDNASAETGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPF9</accession>
    <name>A0A0S2DPF9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Shikimate dehydrogenase (NADP(+))</fullName>
            <shortName evidence="8">SDH</shortName>
            <ecNumber evidence="3 8">1.1.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">aroE</name>
        <name evidence="13" type="ORF">FE772_24215</name>
        <name evidence="12" type="ORF">GLE_4995</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">C3</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>NADP(+) + shikimate = 3-dehydroshikimate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17737"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the shikimate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.25" evidence="3 8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949471.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4995"/>
    <dbReference type="EnsemblBacteria" id="ALN60336">
        <property type="protein sequence ID" value="ALN60336"/>
        <property type="gene ID" value="GLE_4995"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4995"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4923"/>
    <dbReference type="OMA" id="FGNPIKH"/>
    <dbReference type="OrthoDB" id="1054867at2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00087"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004764">
        <property type="term" value="F:shikimate 3-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019632">
        <property type="term" value="P:shikimate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00222">
        <property type="entry name" value="Shikimate_DH_AroE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041121">
        <property type="entry name" value="SDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011342">
        <property type="entry name" value="Shikimate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013708">
        <property type="entry name" value="Shikimate_DH-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022893">
        <property type="entry name" value="Shikimate_DH_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006151">
        <property type="entry name" value="Shikm_DH/Glu-tRNA_Rdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21089">
        <property type="entry name" value="PTHR21089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18317">
        <property type="entry name" value="SDH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01488">
        <property type="entry name" value="Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08501">
        <property type="entry name" value="Shikimate_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00507">
        <property type="entry name" value="aroE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0521">NADP</keyword>
    <keyword evidence="6 8 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Shikimate_dh_N" evidence="10">
        <location>
            <begin position="16"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Shikimate_DH" evidence="9">
        <location>
            <begin position="123"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="SDH_C" evidence="11">
        <location>
            <begin position="249"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate binding" evidence="8">
        <location>
            <begin position="24"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="136"/>
            <end position="140"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="160"/>
            <end position="165"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF18317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN60336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW28288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="289" mass="30713" checksum="79CC0A4BA0FC855A" modified="2016-02-17" version="1">MSIDSSSSSPVLRFAVFGHPVAHSLSPRIHAHFARQFGIALDYAAIDAAAERFDVALAEFAAEGGLGANITLPLKTRAAGICTHLSERARRAGAVNTLIRSATGWEGDNTDGVGLIRDLTERHGLDLRERRTLLIGAGGAARGVAPALLDAGIGDLFIVNRTGERADALADTLGQPGRVHPRYLDDVGNLGNFDLIVNATSAAREHEFPSLPMSLATPRTAAVDLSYGEAAIPFLAWAKVAGAHDRIDGLGMLVEQAAESFERWHRRRPETDPVYALLRQGAGTLVTAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPG8</accession>
    <name>A0A0S2DPG8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF58 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_24230</name>
        <name evidence="3" type="ORF">GLE_4998</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4998"/>
    <dbReference type="EnsemblBacteria" id="ALN60339">
        <property type="protein sequence ID" value="ALN60339"/>
        <property type="gene ID" value="GLE_4998"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4998"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4926"/>
    <dbReference type="OMA" id="RVMKMPF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF58" evidence="2">
        <location>
            <begin position="218"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="461" mass="51396" checksum="8E5ED1991AAE9CA6" modified="2016-02-17" version="1">MSPAPPPLPAVAGAAPAVPRERAQARQAWPRPSLRLGWLALPCAALGLAASAGWLAPQWWQLAALLALAALALDLWRVMRAPTPRVQRRMHDTWAIGVERAVTLQIDGDRRQRLDAFDLHPGGWAMRDLPRRLDLAPGQSTDFEYFLRANSRGDFQFDGTQLRLHSPWGLWWQSRVAGAPQRVRVFPNFAPLAKFAMFSAEQASRLVGAHVKRRRGEGTDFHQMREYRVGDSLRQIDWKATARARRLISREYQDERNQQLVLMLDTGRRLMARDGELSHFDHVLDAALVVSYLALRQGDGVGLLASGGQSRWVPPQRGVGAIDNLLRASYALQPQPVATDFLAAATELSLRQRRRSLVMLVTNLRDEDMDDLLAAVRMLRGRHLVCVASLREGSLDQALGDEVDDLSGAIRAGAAAQYLEHRTQAHEALRSQGVMVLDVACEQLAASLVEKYLAVKRDRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPI9</accession>
    <name>A0A0S2DPI9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TetR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Tetracyclin repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tetR</name>
        <name evidence="8" type="ORF">BV903_07880</name>
        <name evidence="9" type="ORF">FE772_25065</name>
        <name evidence="7" type="ORF">GLE_5173</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000016">
        <property type="protein sequence ID" value="OPD64457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949607.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60514">
        <property type="protein sequence ID" value="ALN60514"/>
        <property type="gene ID" value="GLE_5173"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64457">
        <property type="protein sequence ID" value="OPD64457"/>
        <property type="gene ID" value="BV903_07880"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5173"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5095"/>
    <dbReference type="OMA" id="SALYWHF"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004111">
        <property type="entry name" value="Repressor_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003012">
        <property type="entry name" value="Tet_transcr_reg_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02909">
        <property type="entry name" value="TetR_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00400">
        <property type="entry name" value="TETREPRESSOR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="6">
        <location>
            <begin position="2"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="5">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN60514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD64457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW28434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="207" mass="22865" checksum="3542710FAC9D5495" modified="2016-02-17" version="1">MKLQRETVVAAALKLLDEVGMDGLTTRRLAQDLGVQQPSLYWHFKNKRELLDALAEAMLAGHRPVDRAACADWREWMAAQSREFRRCLLAHRDGARVHVGTRPQPHDFGEVEAELAYLTAAGFSASDAIRALISLSYYTVGWVLEEQAATEAGRGPGQAPMSPDPQRYPLLAQAQPVMSQSDIEADYEYGLRALIAGFEVSIARRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPK0</accession>
    <name>A0A0S2DPK0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AAA family ATPase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">ATPase family associated with various cellular activities (AAA)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_25070</name>
        <name evidence="2" type="ORF">GLE_5175</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949608.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5175"/>
    <dbReference type="EnsemblBacteria" id="ALN60516">
        <property type="protein sequence ID" value="ALN60516"/>
        <property type="gene ID" value="GLE_5175"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5175"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5096"/>
    <dbReference type="OMA" id="EAMHIGF"/>
    <dbReference type="OrthoDB" id="1115436at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="265"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW28435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="494" mass="55064" checksum="12E214DAF2C8ED29" modified="2016-02-17" version="1">MSDLQDLTALIRANTPLIVIETRDETRVVELFRQALMNVWRALYRWSITEGLRRIDLDREDESETAPDISNTLQAIRHADQRGIYLLFDAHPYLVYAGTQRQLREIAQRRECEPHVLVMIGHKLELPPDLDALAVRFTPRLPDANALLKLVREEAENYARENGGRRVEADGEAVQQIVRNLQGIDPVDARRIARHLIFRDGALNADDLPELAKLKFELLNRSGHLHYEYDSARMTEVAGARRLKRWVEQRRAVFAGAQPPPGLDPPKGLLLLGVQGCGKSMIAKAVAAGFGVPLVRLDFGTLYDKFHGETEKNLRAALASAEQLAPAVLWIDEIEKGLADSGDSDGGVSRRVLGYLLTWMAERKSKLFLVATANQIDALPPELLRKGRFDEIFFVDLPAADVREELFAIHLRRRSLDPAGFDLAALAAASDGFSGAEIEQAIVAAMYAAHAAGTALSDFQVRAELKQTRPLSVVMGERVTQLREWARGRTVPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPL1</accession>
    <name>A0A0S2DPL1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Superoxide dismutase [Cu-Zn]</fullName>
            <ecNumber evidence="4">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">sodC</name>
        <name evidence="9" type="ORF">FE772_24460</name>
        <name evidence="8" type="ORF">GLE_5046</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2 H(+) + 2 superoxide = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="4">Binds 1 copper ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the Cu-Zn superoxide dismutase family.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949513.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5046"/>
    <dbReference type="EnsemblBacteria" id="ALN60387">
        <property type="protein sequence ID" value="ALN60387"/>
        <property type="gene ID" value="GLE_5046"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5046"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4974"/>
    <dbReference type="OMA" id="KWVAFHV"/>
    <dbReference type="OrthoDB" id="2015673at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00305">
        <property type="entry name" value="Cu-Zn_Superoxide_Dismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036423">
        <property type="entry name" value="SOD-like_Cu/Zn_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024134">
        <property type="entry name" value="SOD_Cu/Zn_/chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018152">
        <property type="entry name" value="SOD_Cu/Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001424">
        <property type="entry name" value="SOD_Cu_Zn_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10003">
        <property type="entry name" value="PTHR10003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00080">
        <property type="entry name" value="Sod_Cu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00068">
        <property type="entry name" value="CUZNDISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49329">
        <property type="entry name" value="SSF49329"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00087">
        <property type="entry name" value="SOD_CU_ZN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00332">
        <property type="entry name" value="SOD_CU_ZN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0186">Copper</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 4" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726823" description="Superoxide dismutase [Cu-Zn]" evidence="6">
        <location>
            <begin position="19"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Sod_Cu" evidence="7">
        <location>
            <begin position="57"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN60387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW28331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="191" mass="18520" checksum="EE29BD6B2DFAEFEE" modified="2016-02-17" version="1">MNATLRIAVLAAATAALAACGGQSVKPTPPPAATAKPVSTASSASVVLASASGSLVSGKLNVRPMGDGVHITGEIGGLTPNSTHAIHIHEKGDCSAADATSAGGHFNPAAQPHGQVDHGAHHAGDMDNLVANAEGVAKVDAHASGVTLGGGAPNDVAGRAVIVHASADDYKTQPTGNAGARLACGVIKTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPT2</accession>
    <name>A0A0S2DPT2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aspartate racemase</fullName>
            <ecNumber evidence="2">5.1.1.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5274</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aspartate/glutamate racemases family.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.13" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5274"/>
    <dbReference type="EnsemblBacteria" id="ALN60615">
        <property type="protein sequence ID" value="ALN60615"/>
        <property type="gene ID" value="GLE_5274"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5274"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5192"/>
    <dbReference type="OMA" id="TNTMHLI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047689">
        <property type="term" value="F:aspartate racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015942">
        <property type="entry name" value="Asp/Glu/hydantoin_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001920">
        <property type="entry name" value="Asp/Glu_race"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004380">
        <property type="entry name" value="Asp_race"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21198:SF7">
        <property type="entry name" value="PTHR21198:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01177">
        <property type="entry name" value="Asp_Glu_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53681">
        <property type="entry name" value="SSF53681"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00035">
        <property type="entry name" value="asp_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="237" mass="25780" checksum="16437F35F846F2D5" modified="2016-02-17" version="1">MSEPHLRTLGLLGGMSWESTLPYYRLINQTVRERLGGLHSAHLLLYSVDFAQVERLQHAGDWDAAGALLGRAACALRDGGAQLLVICTNTMHKVADAVERAAQLPLLHIADPTGEAIRAAGLTRIGLLGTRFTMEQDFYRRRLVERHGLEVLVPEPDGRDFVHRVIYDELCVGQIRDASREGYRRIVDGLAARGAQAVILGCTEIGLLLGADDVDLPLFDTTALHARAAALASIGQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPZ0</accession>
    <name>A0A0S2DPZ0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5136</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60477">
        <property type="protein sequence ID" value="ALN60477"/>
        <property type="gene ID" value="GLE_5136"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5136"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5061"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="157" mass="17637" checksum="05128F2B0218AE5F" modified="2016-02-17" version="1">MGSGVHFDSFLLVRTCVRGRGDALGVKLTPARARRRDGAVGRTGHWQALGLRANGAGGPGVAGCFRRLSRYLGRRGSRRFRKGFGGLRNRRREPRPRHWSGDANSEERSRSAEPAWFARSEAKLSPRTIASHRERPAELFAHVRSRDKKRRQPFPIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ50</accession>
    <name>A0A0S2DQ50_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SIS domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_5196</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5196"/>
    <dbReference type="EnsemblBacteria" id="ALN60537">
        <property type="protein sequence ID" value="ALN60537"/>
        <property type="gene ID" value="GLE_5196"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5196"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5115"/>
    <dbReference type="OMA" id="QSFYVMA"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="SIS" evidence="2">
        <location>
            <begin position="44"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="2">
        <location>
            <begin position="208"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="354" mass="37066" checksum="C76DAD80BE6668A9" modified="2016-02-17" version="1">MSADTPPDPTPLDPSSTRMYAEAQEAGDAVARQFQANADIVDELAQRLRAQPPRFIVTCARGSSDHAATYGKYLFETQLGLVTASASPSVGSVYAIKPQLQDSLFVAVSQSGKSPDLVRNAEIAKSAGAHVLALVNVADSPLAQIADTVLPLHAGPEKSVAATKSYLCSLAAMLQLTARWSSDAKLFDAVHALPEALRQAFAQDWSPLVEGLRDAHNLFVIGRGLGLGAAQEAALKFKETCALHAEAFSSAEVKHGPMAIVGPGFPVLAFAQDDGTGDGTVAVAREFRQRGAPVWLAAPGIHGGDALPLARSLHPAMTPLLTVASFYKAANALSVARGLNPDVPPHLNKVTETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQW7</accession>
    <name>A0A0S2DQW7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Type I restriction modification system, subunit S</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hsdS</name>
        <name evidence="5" type="ORF">GLE_0006</name>
        <name evidence="6" type="ORF">GLE_5544</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-I restriction system S methylase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0006"/>
    <dbReference type="REBASE" id="131996">
        <property type="entry name" value="S.LenC3ORF5543P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55365">
        <property type="protein sequence ID" value="ALN55365"/>
        <property type="gene ID" value="GLE_0006"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60885">
        <property type="protein sequence ID" value="ALN60885"/>
        <property type="gene ID" value="GLE_5544"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0006"/>
    <dbReference type="KEGG" id="lez:GLE_5544"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5465"/>
    <dbReference type="OMA" id="HWEVKRL"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.220.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000055">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044946">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01420">
        <property type="entry name" value="Methylase_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="345"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN55365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN60885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="428" mass="47660" checksum="8CC2936DE6C775CB" modified="2016-02-17" version="1">MTPLLPKERMKDSGIPWIGLIPKTWDMKRAKFLFSLAQRAPLPDDGIVTAFRNGQVTLRSNRRTDGFTNALKEAGYQRVHKGDLVIHAMDAFAGAIGVSDSDGKCTPVYSCCVPSIEASSEFYARCVRTMSTTGFIESLAKGIRERSTDFRWATFAEQLLPHPPKGEQDVIVSYLDRATTRIDALVSKKTRFIELLREKRQAVVARAVTKGVDPNVPMKDSGVEWLGEVPAHWDVVPPGVLFTDSKERAHTGDQLLSATQKYGVIPLAEFEALEQRQVTKATTNFELRKHVEVGDFVISMRSMDGGIERSHATGSVRSSYSVLKARCEVYGPYFGLLLKSSLFIQALRLTSNFIRDGQDLNFAHVKKIKLPLPDLGEQKKISDCVDRATSRIDILIIKTERSIELLREHRTALITAAVTGKIDLRLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DRE6</accession>
    <name>A0A0S2DRE6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5419</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60760">
        <property type="protein sequence ID" value="ALN60760"/>
        <property type="gene ID" value="GLE_5419"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5419"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5335"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="73" mass="7959" checksum="E29D326E79BEF549" modified="2016-02-17" version="1">MPPRRRRRRGASGPAARAARAKFRCAAARTVENPVFKGFFTYGDGAPARPDQGQTPQAPGFFPCARPQQDTRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAI6</accession>
    <name>A0A0S2DAI6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2170 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_01785</name>
        <name evidence="1" type="ORF">GLE_0182</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945857.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0182"/>
    <dbReference type="EnsemblBacteria" id="ALN55541">
        <property type="protein sequence ID" value="ALN55541"/>
        <property type="gene ID" value="GLE_0182"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0182"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.184"/>
    <dbReference type="OMA" id="EVWILPE"/>
    <dbReference type="OrthoDB" id="1029845at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019231">
        <property type="entry name" value="DUF2170"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09938">
        <property type="entry name" value="DUF2170"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="207" mass="23162" checksum="18EC29E7DB6AA3FC" modified="2016-02-17" version="1">MERRSSAYYQRRHRERLREKGLVKKELWVLPEFADELLAVEKRMRQPRGAAAGRGQVERDMNDGKVWTASGLYDALCQVEEFVYGDSQIELIDGAEPSLHLVMAEYGDLPLFVAVVGEQIVVEALLWPVAHVRDAAAFNEEVLRTHKVFPLSTIGIETLADGEAVYMMFGALSATSSLSNVLYEIETLADNVIKATEAYETQLLEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAK5</accession>
    <name>A0A0S2DAK5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2-hydroxymuconic semialdehyde hydrolase</fullName>
            <ecNumber evidence="3">3.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">dmpD</name>
        <name evidence="3" type="ORF">GLE_0231</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945888.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0231"/>
    <dbReference type="EnsemblBacteria" id="ALN55590">
        <property type="protein sequence ID" value="ALN55590"/>
        <property type="gene ID" value="GLE_0231"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0231"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.233"/>
    <dbReference type="OMA" id="WPLGSHT"/>
    <dbReference type="OrthoDB" id="1119700at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595159" evidence="1">
        <location>
            <begin position="24"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="73"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="336" mass="36729" checksum="974D8FCA5F5FF131" modified="2016-02-17" version="1">MNRRTFLLGGSGLLAAGSLGAIARVPGLAVAATDGADARPDLDAAEFHASRKFARTAFGDIAYVERGEGPAALFLHGFPLNGFQWRGALPRLAPYRRCIAPYWLGLGYTRVAPDQSVDPHAQAAMILALMDALGLDSADLVANDSGGAIAQLLLTAHPQRVRTVLLTNCDTEFDNPPPKLLPVIELSRQGRFVDEWLAPWWQDKALARSPQGFGGMCYADPAHPDDDAIDMYFGPLLSTQRRKALTHAYALGLERNVLEGIGARLGRSRAPARVLWGMADDIFDPAQAQPLADAFGRSRGLRKLEGYKLFWPEERPDVIAEEAQRLWVAWAPQRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAY3</accession>
    <name>A0A0S2DAY3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA N6-adenosine threonylcarbamoyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.234</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">N6-L-threonylcarbamoyladenine synthase</fullName>
            <shortName evidence="6">t(6)A synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">gcp</name>
        <name evidence="6 9" type="synonym">tsaD</name>
        <name evidence="9" type="ORF">FE772_02365</name>
        <name evidence="8" type="ORF">GLE_0310</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>adenosine(37) in tRNA + L-threonylcarbamoyladenylate = AMP + H(+) + N(6)-L-threonylcarbamoyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:37059"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.3.1.234"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="6">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the KAE1 / TsaD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.234" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945943.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0310"/>
    <dbReference type="EnsemblBacteria" id="ALN55668">
        <property type="protein sequence ID" value="ALN55668"/>
        <property type="gene ID" value="GLE_0310"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0310"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.307"/>
    <dbReference type="OMA" id="HLEGHIY"/>
    <dbReference type="OrthoDB" id="1257362at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061711">
        <property type="term" value="F:N(6)-L-threonylcarbamoyladenine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01445">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017861">
        <property type="entry name" value="KAE1/TsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017860">
        <property type="entry name" value="Peptidase_M22_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022450">
        <property type="entry name" value="TsaD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF6">
        <property type="entry name" value="PTHR11735:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00789">
        <property type="entry name" value="OSIALOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00329">
        <property type="entry name" value="gcp_kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03723">
        <property type="entry name" value="T6A_TsaD_YgjD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01016">
        <property type="entry name" value="GLYCOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TsaD" evidence="7">
        <location>
            <begin position="25"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="137"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN55668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW24686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="340" mass="35925" checksum="80787EF7205D395D" modified="2016-02-17" version="1">MKVLGIETSCDETGVAVYDTDAGLRAHALYSQIALHAEYGGVVPELASRDHVRKLLPLIRQTLAEAGLRTDELDGVAYTAGPGLVGALLVGAGVARALAWALDVPAIGVHHMEGHLLAPLMEDDPLGRPEPPFVALLVSGGHTQLVAVDRIGQYRLLGETLDDAAGEAFDKTAKLMGLPYPGGPQLAAQAELGTPGRFKFARPMTDRPGLDFSFSGLKTQVLLAWQNSDKTEQTRADIARAFEDAVVDTLAIKCERALDAAGCDTLVVAGGVGANQRLRARLAAMAAKRGGRVAFPRPMFCTDNGAMIAYAGALRLQAGQRADASVRVTPRWDMALLDAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB60</accession>
    <name>A0A0S2DB60_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_02860</name>
        <name evidence="1" type="ORF">GLE_0414</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946017.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0414"/>
    <dbReference type="EnsemblBacteria" id="ALN55772">
        <property type="protein sequence ID" value="ALN55772"/>
        <property type="gene ID" value="GLE_0414"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0414"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.411"/>
    <dbReference type="OMA" id="VATCCNT"/>
    <dbReference type="OrthoDB" id="1555973at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046149">
        <property type="entry name" value="DUF6151"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19648">
        <property type="entry name" value="DUF6151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN55772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="178" mass="19381" checksum="1AA6660E2ADD6695" modified="2016-02-17" version="1">MSSTRSLACACGQLAVEVEGPPIASVECCCDSCREAGARLARLPGARPVLGAHGATRFVLQRKDRVRFVRGAQQLRQFRLAPGAGTRRVVAACCNTPVFMEFKGGHWLSLYGGLWRDGALPPLQMRTMTGDLEDPSALPDDVPNLRRQSLSFYARLMKAWIAMGFRVPQIAVAGDLHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB99</accession>
    <name>A0A0S2DB99_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Type VI secretion system Vgr family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_0455</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946049.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0455"/>
    <dbReference type="EnsemblBacteria" id="ALN55813">
        <property type="protein sequence ID" value="ALN55813"/>
        <property type="gene ID" value="GLE_0455"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0455"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.453"/>
    <dbReference type="OMA" id="NADAQHN"/>
    <dbReference type="OrthoDB" id="1880900at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006531">
        <property type="entry name" value="Gp5/Vgr_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028244">
        <property type="entry name" value="T6SS_Rhs_Vgr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037026">
        <property type="entry name" value="Vgr_OB-fold_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018769">
        <property type="entry name" value="VgrG2_C_DUF2345"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10106">
        <property type="entry name" value="DUF2345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04717">
        <property type="entry name" value="Phage_base_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13296">
        <property type="entry name" value="T6SS_Vgr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage_base_V" evidence="2">
        <location>
            <begin position="480"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="domain" description="T6SS_Vgr" evidence="4">
        <location>
            <begin position="615"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2345" evidence="3">
        <location>
            <begin position="757"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN55813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="945" mass="100640" checksum="D97124312D6D7A62" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBD4</accession>
    <name>A0A0S2DBD4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_03185</name>
        <name evidence="2" type="ORF">GLE_0489</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946073.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0489"/>
    <dbReference type="EnsemblBacteria" id="ALN55847">
        <property type="protein sequence ID" value="ALN55847"/>
        <property type="gene ID" value="GLE_0489"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0489"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.484"/>
    <dbReference type="OrthoDB" id="1621438at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242171" evidence="1">
        <location>
            <begin position="27"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="150" mass="15403" checksum="842940C67A12CCC7" modified="2016-02-17" version="1">MTMRIAGIAVLAFALAGTFAAQPARAAGAETKCHMTFDTSGWAVIYKHINGSGRVTCDNGETAKVKIHVRGAGLTAGKYSIENGKGEFTKLNGISEIYGTYVTAGANAGVVKSAEGLVMTKGQVSLAVSGTGRGFNLGVDVSGFEIVRAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBY5</accession>
    <name>A0A0S2DBY5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP synthase subunit delta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">ATP synthase F(1) sector subunit delta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">F-type ATPase subunit delta</fullName>
            <shortName evidence="7">F-ATPase subunit delta</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 8" type="primary">atpH</name>
        <name evidence="9" type="ORF">BV903_08405</name>
        <name evidence="10" type="ORF">FE772_04115</name>
        <name evidence="8" type="ORF">GLE_0686</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="function">
        <text evidence="7">This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the ATPase delta chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000017">
        <property type="protein sequence ID" value="OPD64431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946215.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000017.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0686"/>
    <dbReference type="EnsemblBacteria" id="ALN56044">
        <property type="protein sequence ID" value="ALN56044"/>
        <property type="gene ID" value="GLE_0686"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64431">
        <property type="protein sequence ID" value="OPD64431"/>
        <property type="gene ID" value="BV903_08405"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0686"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.674"/>
    <dbReference type="OMA" id="MVDNIQD"/>
    <dbReference type="OrthoDB" id="1937493at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01416">
        <property type="entry name" value="ATP_synth_delta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026015">
        <property type="entry name" value="ATP_synth_OSCP/delta_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000711">
        <property type="entry name" value="ATPase_OSCP/dsu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11910">
        <property type="entry name" value="PTHR11910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00213">
        <property type="entry name" value="OSCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00125">
        <property type="entry name" value="ATPASEDELTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47928">
        <property type="entry name" value="SSF47928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01145">
        <property type="entry name" value="ATP_synt_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0139">CF(1)</keyword>
    <keyword evidence="2 7" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN56044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD64431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW24977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="175" mass="18434" checksum="850FAB3860C8813B" modified="2016-02-17" version="1">MSQNLTLARPYARAAFALARDAGRTADWSQALAFSARVAADPQVQSVLGHPRLSVSDAVALVAIDHADEPVQRFLTLLADNRRLALLPEIAGLFEELRADADRVVKAKVTSASDLPAAELDSIKAALVKRFGRQVEIETAIDASLIGGAVIDAGEVVIDGSLKGKLARLQTALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBY9</accession>
    <name>A0A0S2DBY9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rsuA</name>
        <name evidence="6" type="ORF">FE772_04000</name>
        <name evidence="5" type="ORF">GLE_0661</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946195.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0661"/>
    <dbReference type="EnsemblBacteria" id="ALN56019">
        <property type="protein sequence ID" value="ALN56019"/>
        <property type="gene ID" value="GLE_0661"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0661"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.650"/>
    <dbReference type="OMA" id="HVPKTYE"/>
    <dbReference type="OrthoDB" id="1037615at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00093">
        <property type="entry name" value="TIGR00093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="4">
        <location>
            <begin position="61"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW24957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="233" mass="25497" checksum="1AE1D7EF7100079D" modified="2016-02-17" version="1">MKLVKLIANLGYGSRKDVAAMFRQGRIADADGEVLYADDQVEHAAIRIDGEPLDPPAGLALMLHKPVGYTCSTKDPGRVVYDLLPPRFRLRSPLLSPVGRLDRDTSGLLLLTDDGALLHRIVSPKAKLGKVYEATLAADLRGDEAATFASGELMLESEKTPLAPALLETLEPRRARLTLTEGRYHQVRRMFAAVGNHVEALHRARIGGLSLQDLPSGQWRALDSTDLETLFRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBZ2</accession>
    <name>A0A0S2DBZ2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF885 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_04160</name>
        <name evidence="2" type="ORF">GLE_0696</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946224.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0696"/>
    <dbReference type="EnsemblBacteria" id="ALN56054">
        <property type="protein sequence ID" value="ALN56054"/>
        <property type="gene ID" value="GLE_0696"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0696"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.684"/>
    <dbReference type="OMA" id="GMEVVRI"/>
    <dbReference type="OrthoDB" id="520320at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="PTHR33361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242134" evidence="1">
        <location>
            <begin position="34"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="617" mass="69201" checksum="C0E7F1E7F9B88518" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC17</accession>
    <name>A0A0S2DC17_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent dethiobiotin synthetase BioD</fullName>
            <ecNumber evidence="5">6.3.3.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">DTB synthetase</fullName>
            <shortName evidence="5">DTBS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Dethiobiotin synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">bioD</name>
        <name evidence="7" type="ORF">FE772_04280</name>
        <name evidence="6" type="ORF">GLE_0718</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(7R,8S)-7,8-diammoniononanoate + ATP + CO2 = (4R,5S)-dethiobiotin + ADP + 3 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15805"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:149469"/>
            <dbReference type="ChEBI" id="CHEBI:149473"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the dethiobiotin synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.3" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946246.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0718"/>
    <dbReference type="EnsemblBacteria" id="ALN56076">
        <property type="protein sequence ID" value="ALN56076"/>
        <property type="gene ID" value="GLE_0718"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0718"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.706"/>
    <dbReference type="OMA" id="KMLLISH"/>
    <dbReference type="OrthoDB" id="1739932at2"/>
    <dbReference type="UniPathway" id="UPA00078">
        <property type="reaction ID" value="UER00161"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004141">
        <property type="term" value="F:dethiobiotin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00336">
        <property type="entry name" value="BioD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004472">
        <property type="entry name" value="DTB_synth_BioD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43210">
        <property type="entry name" value="PTHR43210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006755">
        <property type="entry name" value="DTB_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="5 6" id="KW-0436">Ligase</keyword>
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        <location>
            <begin position="18"/>
            <end position="23"/>
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        <ligand>
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        <location>
            <position position="22"/>
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        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:18420"/>
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        <ligand>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022756"/>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="228" mass="23706" checksum="6C26DF72E6150897" modified="2016-02-17" version="1">MTSARRLPGLFVTGTDTGIGKSVASAALLHALRAGGARAVGMKPVASGCEPGPDGWRNEDALLLQAASDPRPRYEDVNPYALPQPLAPEIAAAEAGVEIALGPILAAHARLAAQADTVVVEGVGGWAAPVSAQLDQIDLVRALKLPVVLVVGLRLGAINHARLSARAIQADGAELIGWIANGIDPHMARADENFEILRRRLPVPCWGRLPHAAQPDPATLAGALRPVF</sequence>
</entry>
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    <accession>A0A0S2DC51</accession>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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            <end position="117"/>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="EMBL" id="ALN55965.1"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="OPD63063.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
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    </evidence>
    <sequence length="154" mass="16187" checksum="24D0B085110F52E3" modified="2016-02-17" version="1">MQRTTIDMLLGRLDAAPSSEGATQDVLAAELQRCWERVPGVRALCVSTADGRALAERLDGGADARRIAAMANSFLTLGETLAREIELSQADYATVCTARGNLVLFRIHAAKPLTLLAMAGPDTLLAALLVGARDCAARIGAALSEPRTAALAER</sequence>
</entry>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
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            <dbReference type="EMBL" id="ALN56106.1"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="QCW25028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="236" mass="26619" checksum="72F675E38B84BF88" modified="2016-02-17" version="1">MPLEFKPRPPPGPPPSGRGLLRSLARKLMILAALAAVLVLWAGWQYSQRQSADSKTLSDYRIGGDAVTVLLVEPDVSLDIEAGLRRDYTAQLARALGQRLEQLGYRVRPLSARSEQERFGETSQLRDRRAAIEHQTQTLQSLRETAAPVLRVSLDGLDYDGRSVSQHRYKVELLDPRSLEPSWQAVLTWREGRSQSIALLWHLRQNRLPPPLWDSLAELALERLREDGKLPASAIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC74</accession>
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            <fullName evidence="1">Uncharacterized protein</fullName>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ALN56124">
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        <property type="gene ID" value="GLE_0766"/>
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    <dbReference type="KEGG" id="lez:GLE_0766"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="106" mass="12132" checksum="2B5F14DD87EA2331" modified="2016-02-17" version="1">MWLLLLLLLLLLLLLLLLLLLLLLLFLLLLLRVLAPERDAVVLQPRRACAWMRTRAMGQDAPYGAAPRLFRALVALDPKKIRPFLWLLSLWLKTKKVTRPLADGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC94</accession>
    <name>A0A0S2DC94_LYSEN</name>
    <protein>
        <submittedName>
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        <submittedName>
            <fullName evidence="13">Cytochrome d ubiquinol oxidase, subunit I</fullName>
            <ecNumber evidence="13">1.10.3.-</ecNumber>
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    </protein>
    <gene>
        <name evidence="13" type="primary">cyaA</name>
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    <reference evidence="13 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">C3</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the cytochrome ubiquinol oxidase subunit 1 family.</text>
    </comment>
    <dbReference type="EC" id="1.10.3.-" evidence="13"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW24940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946181.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0639"/>
    <dbReference type="EnsemblBacteria" id="ALN55997">
        <property type="protein sequence ID" value="ALN55997"/>
        <property type="gene ID" value="GLE_0639"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0639"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.628"/>
    <dbReference type="OMA" id="FLINIAM"/>
    <dbReference type="OrthoDB" id="271551at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070069">
        <property type="term" value="C:cytochrome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Fernandez C."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>AMP + ATP = 2 ADP</text>
            <dbReference type="Rhea" id="RHEA:12973"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from ADP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="6 8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000021">
        <property type="protein sequence ID" value="OPD64156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946349.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0857"/>
    <dbReference type="EnsemblBacteria" id="ALN56215">
        <property type="protein sequence ID" value="ALN56215"/>
        <property type="gene ID" value="GLE_0857"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64156">
        <property type="protein sequence ID" value="OPD64156"/>
        <property type="gene ID" value="BV903_09740"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0857"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.846"/>
    <dbReference type="OMA" id="FHNRMRV"/>
    <dbReference type="OrthoDB" id="1491686at2"/>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00649"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:adenylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="PTHR23359"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="4 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="NMP" evidence="6">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="57"/>
            <end position="59"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="85"/>
            <end position="88"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="OPD64156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="QCW25118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="192" mass="20665" checksum="EF2EC43AACC56226" modified="2016-02-17" version="1">MRLVLLGAPGSGKGTQAARLKDHLQVPHISTGDLLRGEVAAGTKLGLEAKAVMDAGNLVSDEILLGMLEDRFSRPDTRGGFILDGYPRNLAQADALDALLQKIGQPMDFAVQLEVPTELLVQRIAGRAAEQGRIDDSPEAVRTRLKVYDDVTAPVIEYYRQHGRLTVVDGVGSLDQVFTRIVEALEPAPTVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCM9</accession>
    <name>A0A0S2DCM9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">50S ribosomal protein L31 type B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpmE</name>
        <name evidence="5" type="synonym">rpmE2</name>
        <name evidence="7" type="ORF">BV903_24930</name>
        <name evidence="9" type="ORF">D9T17_22650</name>
        <name evidence="8" type="ORF">FE772_05275</name>
        <name evidence="6" type="ORF">GLE_0925</name>
    </gene>
    <organism evidence="6 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 10">C3</strain>
        </source>
    </reference>
    <reference evidence="7 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">OH11</strain>
        </source>
    </reference>
    <reference evidence="8 13" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 13">YC36</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2 5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000101">
        <property type="protein sequence ID" value="OPD61201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000056">
        <property type="protein sequence ID" value="ROU04649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946400.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000056.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0925"/>
    <dbReference type="EnsemblBacteria" id="ALN56283">
        <property type="protein sequence ID" value="ALN56283"/>
        <property type="gene ID" value="GLE_0925"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61201">
        <property type="protein sequence ID" value="OPD61201"/>
        <property type="gene ID" value="BV903_24930"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0925"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.913"/>
    <dbReference type="OMA" id="FKDMSND"/>
    <dbReference type="OrthoDB" id="2014569at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00502">
        <property type="entry name" value="Ribosomal_L31_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="L28p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002150">
        <property type="entry name" value="Ribosomal_L31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027493">
        <property type="entry name" value="Ribosomal_L31_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042105">
        <property type="entry name" value="Ribosomal_L31_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33280">
        <property type="entry name" value="PTHR33280"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01197">
        <property type="entry name" value="Ribosomal_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01249">
        <property type="entry name" value="RIBOSOMALL31"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="SSF143800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00105">
        <property type="entry name" value="L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01143">
        <property type="entry name" value="RIBOSOMAL_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN56283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD61201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW25164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROU04649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="81" mass="9251" checksum="52E6E0DE7417D1FC" modified="2016-02-17" version="1">MKAGIHPEYRDVVFQDVTTDFQILTRSTLSSKETIKLDGAEYPLIKVDISSASHPFYTGKHKIMDTSGRVDKFRKRYGAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCZ9</accession>
    <name>A0A0S2DCZ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_04955</name>
        <name evidence="1" type="ORF">GLE_0858</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56216">
        <property type="protein sequence ID" value="ALN56216"/>
        <property type="gene ID" value="GLE_0858"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0858"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.847"/>
    <dbReference type="OMA" id="WIFEKAN"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="163" mass="17861" checksum="4D0BD2DF21B3AF3A" modified="2016-02-17" version="1">MPGSFATPSIPDDAHSRRWYSRHLAAAAEPSLSCGGSARGYRFTWLRSFHHPVIVRVSAQAGVEAVELDGAGGYEPGAVLRRSRAPLTAVQLQALRAAFDALDAAPATQDRNTLDGAEWILERRDASDHRVWVRTSPRDGALHVLGQDMLRLSGWTFPDPQTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDF5</accession>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="204" mass="22342" checksum="CF413DC28E74A4F8" modified="2016-02-17" version="1">MVFDVFGTLVYMRERRRPFRRLVGLLEARGRHGQAGDAARIMSRDVGLAGAAALLGAELVAQELASLERDLQAELASVRLFDDTAATLQALRARGLRLGLCSNLAAPYAPPVRALLPFELDAYAWSFEVGAVKPDPAIYAHVCERLGCAPAEVLMIGDTRADDWLGPRDFGMHSRWLRREGGDTREETIAGLDQVPAEVERLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDP1</accession>
    <name>A0A0S2DDP1_LYSEN</name>
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            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_07150</name>
        <name evidence="1" type="ORF">GLE_1343</name>
    </gene>
    <organism evidence="1 3">
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        <lineage>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56700.1"/>
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    </dbReference>
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        <property type="protein sequence ID" value="ALN56700"/>
        <property type="gene ID" value="GLE_1343"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1343"/>
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    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="171" mass="19329" checksum="51B71EA8B3D6B6F0" modified="2016-02-17" version="1">MRYRALPRAQAIALAGYLRHVDLSLHRATWISRGEVAQYFVERSAGLAQVIDHLAAMPQVPAAQPLSRWARTALRLCNCVRLNPLVDYSLLARARGALRDIADYLDEAAAPTDGRIYPLSYQLRLACFELYDVLCRSDLDRCGMPEHLHQNPILDHRVRPMRSIIGEGWPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE24</accession>
    <name>A0A0S2DE24_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcription elongation factor</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Transcription elongation factor GreAB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_07395</name>
        <name evidence="3" type="ORF">GLE_1396</name>
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    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
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            <taxon>Gammaproteobacteria</taxon>
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    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW25516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1396"/>
    <dbReference type="EnsemblBacteria" id="ALN56753">
        <property type="protein sequence ID" value="ALN56753"/>
        <property type="gene ID" value="GLE_1396"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1396"/>
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    <dbReference type="OMA" id="NWGSPLG"/>
    <dbReference type="OrthoDB" id="1591985at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GreA/GreB_C_sf"/>
    </dbReference>
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        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_C"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="168" mass="18589" checksum="383B8F09A89062BC" modified="2016-02-17" version="1">MSRAFVREGDGESDPGELPELPISEHPNYVTPRGMMLLRSRLNDAIRRVQALDGAIATEAVGARLERAHIQREMRWLQARILGAITIAPERQPSDRVAFGARVEVIDDAGHEHRYRIVGEDEADPERGLISWVSPLARALHGARVGDSVVWKRPAGDANVEVLAIEYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEK7</accession>
    <name>A0A0S2DEK7_LYSEN</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
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    <organism evidence="1 2">
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    <reference evidence="1 2" key="1">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57083">
        <property type="protein sequence ID" value="ALN57083"/>
        <property type="gene ID" value="GLE_1728"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1728"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1706"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="41" mass="4664" checksum="04FC96946EE2AA68" modified="2016-02-17" version="1">MRARVAMQRIGASVFVRACALWATKALRSRVRPMEFVWVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DET2</accession>
    <name>A0A0S2DET2_LYSEN</name>
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        <submittedName>
            <fullName evidence="7">Protein AidB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">aidB</name>
        <name evidence="7" type="ORF">GLE_1722</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the acyl-CoA dehydrogenase family.</text>
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        <source>
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            <dbReference type="EMBL" id="ALN57077.1"/>
        </source>
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        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="548" mass="58868" checksum="12C4221CBC211842" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF36</accession>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="204" mass="22472" checksum="E362962DA5DE4773" modified="2016-02-17" version="1">MLGLALTAAALAAAVSLGSWPFSASRAAATAQAGGDAGAASAAEAGSGVHTMLATPQGRRFQQRRQFQDEAKRFFRDAAALGPAERERRAQALQAQIDRYEQADELSAGETMLLRVGLIRATVPDEARQALLVQQLAQRYRSQAAQHEQAFVEQQARDPKFQAYKRSEARIVAETMAMQQIPGGLTRDEYLRQRLQAERERIYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF70</accession>
    <name>A0A0S2DF70_LYSEN</name>
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        <submittedName>
            <fullName evidence="4">Biofilm PGA synthesis protein</fullName>
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        <submittedName>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="entry name" value="Porin_dom_sf"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <begin position="402"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="699" mass="79065" checksum="B55E48C659AB0EF1" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF94</accession>
    <name>A0A0S2DF94_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransf_11 domain-containing protein</fullName>
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        <name evidence="3" type="ORF">GLE_1659</name>
    </gene>
    <organism evidence="3 5">
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        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000013">
        <property type="protein sequence ID" value="OPD64652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1659"/>
    <dbReference type="EnsemblBacteria" id="ALN57016">
        <property type="protein sequence ID" value="ALN57016"/>
        <property type="gene ID" value="GLE_1659"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64652">
        <property type="protein sequence ID" value="OPD64652"/>
        <property type="gene ID" value="BV903_07105"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1659"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1638"/>
    <dbReference type="OMA" id="YLGPIWR"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="SAM-dependent_MTases_sf"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN57016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD64652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="249" mass="26190" checksum="2810CB6558FA5CBA" modified="2016-02-17" version="1">MPALSHGRQPDPGHGPGPAPGQGAALRWFGEVSGHGLLEVESGAMARVLGASPPLPWAWFGVAAAQPPHGRGVALRRSAEGFDGALRCRLPLPLASEAFGAVLLQHVFDDGADPLPLLGECARILAPGGRLWLATLNPWSPYRLRWARSGLRARDAGHWQAALRSSGFAADPVSLQWLGPRWRAAHGEAGGIGAADVLRAGLALSLTKRVHAAIPPTRLQQLRWQTGLVPRDAAAQRGAAARKREDGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFA8</accession>
    <name>A0A0S2DFA8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_17010</name>
        <name evidence="5" type="ORF">D9T17_18185</name>
        <name evidence="4" type="ORF">FE772_09405</name>
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    <organism evidence="2 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">C3</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 9" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000046">
        <property type="protein sequence ID" value="OPD62640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000044">
        <property type="protein sequence ID" value="ROU05620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947081.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000044.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1834"/>
    <dbReference type="EnsemblBacteria" id="ALN57186">
        <property type="protein sequence ID" value="ALN57186"/>
        <property type="gene ID" value="GLE_1834"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62640">
        <property type="protein sequence ID" value="OPD62640"/>
        <property type="gene ID" value="BV903_17010"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1834"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1805"/>
    <dbReference type="OrthoDB" id="1861716at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595464" evidence="1">
        <location>
            <begin position="28"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU05620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="157" mass="17552" checksum="BBC122200C732D69" modified="2016-02-17" version="1">MKRLLLQVPILALSGAVAVLWAAPAPAQQHTTVLQAENVRFDYAQVLRVTPVYQTLRATTVEQQCDPEAGDKSDSRFQRVLGTVREALGRERDPKPSTGENCRPVPVEREFRRPIAYDVDYVYKGARFRSRLPEDPGNKLKVRVAVTPVVAPISTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFD5</accession>
    <name>A0A0S2DFD5_LYSEN</name>
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        <submittedName>
            <fullName evidence="6">Glycosyltransferase family 1 protein</fullName>
        </submittedName>
        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_09850</name>
        <name evidence="5" type="ORF">GLE_1936</name>
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        <name type="scientific">Lysobacter enzymogenes</name>
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        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1936"/>
    <dbReference type="EnsemblBacteria" id="ALN57287">
        <property type="protein sequence ID" value="ALN57287"/>
        <property type="gene ID" value="GLE_1936"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1936"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1901"/>
    <dbReference type="OMA" id="GFPLFND"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:carbohydrate metabolic process"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:lipid glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033072">
        <property type="term" value="P:vancomycin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
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    <dbReference type="InterPro" id="IPR002213">
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        <property type="match status" value="1"/>
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        <location>
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            <end position="108"/>
        </location>
    </feature>
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        <location>
            <begin position="310"/>
            <end position="377"/>
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    </feature>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
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    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN57287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW25922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="405" mass="42826" checksum="14D1143D4B1DAF90" modified="2016-02-17" version="1">MRVLLSTFGSRGDAEPLAALAAALRAQGAQARVCASPDFAQRLDQAGVELFPVGPPVRDWIREVMADPTPDIPGRGAQIMAMYRDALSVAIEDCDAVVATGLFPATTAAQMLAERHRLPYVYAGYCPTYLPSVHHAPFQFPHSPPPPADADNRERWALNARAMQDTFGDTANRHRAELGLPPTQHLRDRVFTARPWLATDPVLSPWAPTSLCEVVQTGHWILPDDRPLAPDLCAFLDAGEPPVYVGFGSMPLHAWGGSAARIAIEAARTQGCRIVLAGGWAGLIPVDAGDDCYAIGEVNQQALFPRMAAIVHHGGAGTTMAATRAGTPQVIVPQIADQPYWAGRVADLGIGVAHAGAVASVESLSAALATALMPRTRVRAEVVAGMVRGDGAAVAAKRLIDLFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFN8</accession>
    <name>A0A0S2DFN8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DnaJ domain</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">J domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">FE772_09975</name>
        <name evidence="5" type="ORF">GLE_1963</name>
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        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="ALN57314">
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        <property type="gene ID" value="GLE_1963"/>
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    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="2"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="60"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
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        </location>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW25944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="457" mass="51048" checksum="5AF3082B8F1BC471" modified="2016-02-17" version="1">MTPHQRLGVEQDADERAIKRAYARALRRTRPDEDAQAFQTLHEAYQAALSMLRQAEYERWLQESEAESEQDESVEDCGDAPPASAAESRVDASSAAAADDATFAGHNDNDNDNDGDGDGDGDDRIELSIDQIGNAVILGALRLSPGDYEAWLREFPPLYSLYVKDVIAPQLPRALAQAPQLPSAQLEAIVRFFDLDALGTLDTQGHWLLHRLRQRSGVDFGAFLAELRERCAHRNPESLRNWLMYREEVRDPDLRDYVGALLYRELEAGRGASTLPPDAMQLVCEFFAYPENDPLRLRNNALWALTHEDARAFGHPSPKVVEELKRPYSPWRALRVATLQSELSRAVARLGGQLRQACGELPASIDPRQYLFHARLAYRGYWGPWRWAVYLLRTALVLLPLCWFTDLELAASCAGGVLLAQVGWLAYDSLFGHGPAPPRPIRPAAREPDADSADDPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFP4</accession>
    <name>A0A0S2DFP4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gamma-glutamyl-gamma-aminobutyrate hydrolase family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Peptidase C26</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_10455</name>
        <name evidence="1" type="ORF">GLE_2065</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947252.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2065"/>
    <dbReference type="EnsemblBacteria" id="ALN57415">
        <property type="protein sequence ID" value="ALN57415"/>
        <property type="gene ID" value="GLE_2065"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2065"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2030"/>
    <dbReference type="OMA" id="RNGHAYQ"/>
    <dbReference type="OrthoDB" id="1628378at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011697">
        <property type="entry name" value="Peptidase_C26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044668">
        <property type="entry name" value="PuuD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43235">
        <property type="entry name" value="PTHR43235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07722">
        <property type="entry name" value="Peptidase_C26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="266" mass="29404" checksum="251171019EC23F52" modified="2016-02-17" version="1">MTQPARKLLIGLSPRMMRNLPPEYGFRNKTLQYLEQSMAHWVMGSGALVVMIPTVDAEGAVQASDLSVRDYAGALDGLILQGGADIDPVAYGERPSELLMTTDPDRDRFELNLLRAFVEVGKPVLGVCRGMQLINVAHGGSLYQDLVGGGATRAEHYIPAQYDEHKHALRMREDGWLAALYPQVPQPQVNSIHHQGIKQLGEGLEVEAWSEDGIPECVRGRGEGFVVGVQWHPEFHDHRFPELLPGRPLLMAFIEAARERARALAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFQ1</accession>
    <name>A0A0S2DFQ1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Redox-sensitive transcriptional activator SoxR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">soxR</name>
        <name evidence="9" type="ORF">GLE_2078</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2078"/>
    <dbReference type="EnsemblBacteria" id="ALN57428">
        <property type="protein sequence ID" value="ALN57428"/>
        <property type="gene ID" value="GLE_2078"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2078"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2043"/>
    <dbReference type="OMA" id="IHFYEAK"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01110">
        <property type="entry name" value="HTH_SoxR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010211">
        <property type="entry name" value="Redox-sen_tscrpt-act_SoxR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015358">
        <property type="entry name" value="Tscrpt_reg_MerR_DNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30204:SF0">
        <property type="entry name" value="PTHR30204:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00376">
        <property type="entry name" value="MerR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09278">
        <property type="entry name" value="MerR-DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01950">
        <property type="entry name" value="SoxR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00552">
        <property type="entry name" value="HTH_MERR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH merR-type" evidence="8">
        <location>
            <begin position="6"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00014474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN57428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="162" mass="18000" checksum="EE79147BDFE575EA" modified="2016-02-17" version="1">MSMAMELSVGQVAERSGVAVSALHFYEAKGLIHSVRTGGNQRRYSRDTLRRIAVIRVAQRVGMPLATIREALDTLPDSRVPNRADWSRLSAAWKDELEQRIAHLSLMRDTLDQCIGCGCLSLDRCRLANPDDAWGEAGSGAQRWAAALKESRPKRRGKKAQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFT3</accession>
    <name>A0A0S2DFT3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein Ypar24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_09540</name>
        <name evidence="1" type="ORF">GLE_1861</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947103.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57213">
        <property type="protein sequence ID" value="ALN57213"/>
        <property type="gene ID" value="GLE_1861"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1861"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1832"/>
    <dbReference type="OrthoDB" id="410140at1236"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="72" mass="8007" checksum="A6DD37A5466AA651" modified="2016-02-17" version="1">MQIHAQGDAVYLLQRDPDEDEALAALCVPRAELVRQVAQLRERTQGLIARLSGELGADVWTSYVRTEPTFAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFW5</accession>
    <name>A0A0S2DFW5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_10800</name>
        <name evidence="5" type="ORF">FE772_10630</name>
        <name evidence="3" type="ORF">GLE_2102</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000024">
        <property type="protein sequence ID" value="OPD63970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947281.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2102"/>
    <dbReference type="EnsemblBacteria" id="ALN57452">
        <property type="protein sequence ID" value="ALN57452"/>
        <property type="gene ID" value="GLE_2102"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63970">
        <property type="protein sequence ID" value="OPD63970"/>
        <property type="gene ID" value="BV903_10800"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2102"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2066"/>
    <dbReference type="OMA" id="EMLEIWY"/>
    <dbReference type="OrthoDB" id="1871130at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="2">
        <location>
            <begin position="5"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="1">
        <location>
            <position position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD63970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="95" mass="10384" checksum="3346C29C703FD3F5" modified="2016-02-17" version="1">MSKQDEATNAVLDVINDIKKTGFTRDTVDHDSYLGGDLGVDSREMLEIWYELEQRLGVAVGDAEKRDLYTLGDVVALLQRKLEGADAGREAVAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-06-17" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG06</accession>
    <name>A0A0S2DG06_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2042</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947238.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57392">
        <property type="protein sequence ID" value="ALN57392"/>
        <property type="gene ID" value="GLE_2042"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2042"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2007"/>
    <dbReference type="OrthoDB" id="1509696at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594771" evidence="2">
        <location>
            <begin position="28"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="552" mass="59883" checksum="49BFC4B99D2E0E22" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG51</accession>
    <name>A0A0S2DG51_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Oxidoreductase, short chain dehydrogenase/reductase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2191</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947352.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2191"/>
    <dbReference type="EnsemblBacteria" id="ALN57540">
        <property type="protein sequence ID" value="ALN57540"/>
        <property type="gene ID" value="GLE_2191"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2191"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2153"/>
    <dbReference type="OMA" id="AMHRTNI"/>
    <dbReference type="OrthoDB" id="1821409at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="250" mass="25474" checksum="092FD5DE3410BEB1" modified="2016-02-17" version="1">MSAQTALPTPAALVTGASRGIGRAIALRLAADGFAVAVNYAGNVAAADAVVAEIESAGGRAVALQGDVADADGMRRVFATAKAAFGRLDAVVNSAGVMPYVPVQGGDLAEFDRVIATNLRGSYIVLGLAAEHLGDGGRIVALSTSVIGKAFPNYGPYIASKAGVEGLVHVLANELRGRNITVNAVAPGPVATELFLNGKTPEQIAHFQSLAPLERLGAPEEIAAAVAFLVGRDGSWVNSQVLRVNGGYIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG57</accession>
    <name>A0A0S2DG57_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DedA family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_10195</name>
        <name evidence="3" type="ORF">GLE_2008</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947207.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57358">
        <property type="protein sequence ID" value="ALN57358"/>
        <property type="gene ID" value="GLE_2008"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2008"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1974"/>
    <dbReference type="OMA" id="WSLLFAW"/>
    <dbReference type="OrthoDB" id="1928533at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1 3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726801" evidence="2">
        <location>
            <begin position="24"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="140" mass="15463" checksum="C3CF4AF417246566" modified="2016-02-17" version="1">MVYLGLFLIAFIAATLLPAQSEAALAAAIVEGYAPWLLVAVATVGNVLGSAVNWWLGRELNRFGDRRWFPVKPAQLARARGWYGRYGRWSLLLSWVPVIGDPLTLVAGVMREPLRTFVPLVAFAKLARYLVVAAVALRWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGF2</accession>
    <name>A0A0S2DGF2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Luciferase-like monooxygenase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2119</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">To bacterial alkanal monooxygenase alpha and beta chains.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947294.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2119"/>
    <dbReference type="EnsemblBacteria" id="ALN57469">
        <property type="protein sequence ID" value="ALN57469"/>
        <property type="gene ID" value="GLE_2119"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2119"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2083"/>
    <dbReference type="OMA" id="APGSDQM"/>
    <dbReference type="OrthoDB" id="1003376at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019949">
        <property type="entry name" value="Luciferase_OxRdatse_group-1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03558">
        <property type="entry name" value="oxido_grp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="2">
        <location>
            <begin position="17"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="329" mass="35256" checksum="B2EC47A830B1C2A9" modified="2016-02-17" version="1">MLPYSVLDLAPVCQGSDTRQAFANSLDLARHAEALGYTRYWLAEHHNMPGIASAATAVLIGHIAGGTSRIRVGAGGIMLPNHAPLQVAEQFGTLASLYPGRIDLGLGRAPGTDHATARALRRYYDGADSFPQDVAELLHYFEPAQPQQAVRAVPGAGLDVPVWLLGSSLFSARLSAAMGLPFAFASHFAPDAMDEALTLYRRDFQPSARLQAPHAMLALNVVAAADSAQARRLFTTQQQAFVNLRRGRPGLIPPPIDDIENFWTPLEKAGVAQALACAVVGDPGEVAEGIAAFVARHRPDELMVTANIFEHAARLRSFELAAQALKSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGH7</accession>
    <name>A0A0S2DGH7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_11695</name>
        <name evidence="2" type="ORF">GLE_2332</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947459.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2332"/>
    <dbReference type="EnsemblBacteria" id="ALN57681">
        <property type="protein sequence ID" value="ALN57681"/>
        <property type="gene ID" value="GLE_2332"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2332"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2296"/>
    <dbReference type="OMA" id="AFMQKGN"/>
    <dbReference type="OrthoDB" id="1015404at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032638">
        <property type="entry name" value="Porin_5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16930">
        <property type="entry name" value="Porin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242563" evidence="1">
        <location>
            <begin position="35"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="579" mass="63152" checksum="2D600524472A8448" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGW6</accession>
    <name>A0A0S2DGW6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Filamentous hemagglutinin family outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_2335</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947462.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2335"/>
    <dbReference type="EnsemblBacteria" id="ALN57684">
        <property type="protein sequence ID" value="ALN57684"/>
        <property type="gene ID" value="GLE_2335"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2335"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2299"/>
    <dbReference type="OMA" id="AVGNWLW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021026">
        <property type="entry name" value="Filamn_hemagglutn_DUF3739"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008638">
        <property type="entry name" value="Filamn_hemagglutn_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12545">
        <property type="entry name" value="DUF3739"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05860">
        <property type="entry name" value="Haemagg_act"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00912">
        <property type="entry name" value="Haemagg_act"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01901">
        <property type="entry name" value="adhes_NPXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595017" evidence="2">
        <location>
            <begin position="40"/>
            <end position="3996"/>
        </location>
    </feature>
    <feature type="domain" description="Haemagg_act" evidence="3">
        <location>
            <begin position="148"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3061"/>
            <end position="3089"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN57684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="3996" mass="411979" checksum="C4FDF01D5C2A4E25" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGY1</accession>
    <name>A0A0S2DGY1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ROK family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Transcriptional regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_01720</name>
        <name evidence="4" type="ORF">FE772_12730</name>
        <name evidence="2" type="ORF">GLE_2535</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000003">
        <property type="protein sequence ID" value="OPD65738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947616.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2535"/>
    <dbReference type="EnsemblBacteria" id="ALN57884">
        <property type="protein sequence ID" value="ALN57884"/>
        <property type="gene ID" value="GLE_2535"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65738">
        <property type="protein sequence ID" value="OPD65738"/>
        <property type="gene ID" value="BV903_01720"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2535"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2497"/>
    <dbReference type="OMA" id="RRSFRCP"/>
    <dbReference type="OrthoDB" id="1130699at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD65738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="416" mass="44635" checksum="575D65A0480B4334" modified="2016-02-17" version="1">MNLGRGATQQSSAPYNRRLVLDFIRQHGAASRKDIQEKVSLSPQTVANITNELESIGLIVSRRQKDLKTRGQPPIAFEINPDAGQSIGISLEPGRASGALVNLVGRIDARCEVQLQGCDRPQLLAGLLELVATLRRQANARLWGIGVALPGPLGDTELSFVGPTALEGWKDLSILDQLQEATGLPLFHSVDSVAGALGETSYGVARHLDTFFYLHLSMGLGGSLIVGRNHYRGADGNATEIGHVPVVPGGTPCYCGNQGCLERYLSLHSLAEALGLDDAQVHTPDLLARLDQAGDPALQQWCAQAAQRLRDAVCMIENLFDPQTIVIGGSAPQALVQRLVELAQPLHRSVRGRPDPELPRVMISQREEDCSLLGAAVLPIHELLSPRLEGVQKDGFGELQAAELLGHRPAAGGRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH27</accession>
    <name>A0A0S2DH27_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_02095</name>
        <name evidence="5" type="ORF">D9T17_14205</name>
        <name evidence="4" type="ORF">FE772_11815</name>
        <name evidence="2" type="ORF">GLE_2360</name>
    </gene>
    <organism evidence="2 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">C3</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 9" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000004">
        <property type="protein sequence ID" value="OPD65577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000035">
        <property type="protein sequence ID" value="ROU06309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947477.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000035.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57709">
        <property type="protein sequence ID" value="ALN57709"/>
        <property type="gene ID" value="GLE_2360"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65577">
        <property type="protein sequence ID" value="OPD65577"/>
        <property type="gene ID" value="BV903_02095"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2360"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2321"/>
    <dbReference type="OMA" id="WATVNRQ"/>
    <dbReference type="OrthoDB" id="2073466at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD65577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU06309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="60" mass="6941" checksum="FB3DAD82910C1012" modified="2016-02-17" version="1">MPRGDKSSYTDKQKRQAEHIEESYRKEGVPKQEAEERAWRTVNKQDHGGKKSGSGRKDSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH45</accession>
    <name>A0A0S2DH45_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome bo(3) ubiquinol oxidase subunit 1</fullName>
            <ecNumber evidence="8">7.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Cytochrome o ubiquinol oxidase subunit 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Oxidase bo(3) subunit 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">Ubiquinol oxidase polypeptide I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Ubiquinol oxidase subunit 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="primary">cyoB</name>
        <name evidence="21" type="ORF">FE772_11895</name>
        <name evidence="20" type="ORF">GLE_2376</name>
    </gene>
    <organism evidence="20 22">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="20 22" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="20 22">C3</strain>
        </source>
    </reference>
    <reference evidence="21 23" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 23">YC36</strain>
        </source>
    </reference>
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        <reaction evidence="1">
            <text>2 a ubiquinol + n H(+)(in) + O2 = 2 a ubiquinone + n H(+)(out) + 2 H2O</text>
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            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="EC" id="7.1.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>a quinone</name>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>heme o</name>
            <dbReference type="ChEBI" id="CHEBI:24480"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterooctamer of two A chains, two B chains, two C chains and two D chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the heme-copper respiratory oxidase family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.3" evidence="8"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="QCW26268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947493.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2376"/>
    <dbReference type="EnsemblBacteria" id="ALN57725">
        <property type="protein sequence ID" value="ALN57725"/>
        <property type="gene ID" value="GLE_2376"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2376"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2337"/>
    <dbReference type="OMA" id="FWGKMSF"/>
    <dbReference type="OrthoDB" id="316745at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="C:respirasome"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:cytochrome bo3 ubiquinol oxidase activity"/>
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        <property type="project" value="UniProtKB-EC"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="F:oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor"/>
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Cyt_C_Oxase_1"/>
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        <property type="entry name" value="Cyt_c_Oxase_su1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014207">
        <property type="entry name" value="Cyt_c_ubiqinol_oxidase_su1"/>
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        <property type="entry name" value="PTHR10422"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="CYCOXIDASEI"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="COX1_CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17" id="KW-0249">Electron transport</keyword>
    <keyword evidence="17" id="KW-0349">Heme</keyword>
    <keyword evidence="17" id="KW-0408">Iron</keyword>
    <keyword evidence="12 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="17" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="10 17 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 18" id="KW-1133">Transmembrane helix</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
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            <begin position="113"/>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
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            <end position="179"/>
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    <feature type="transmembrane region" description="Helical" evidence="18">
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    <feature type="transmembrane region" description="Helical" evidence="18">
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
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    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
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            <end position="342"/>
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    <feature type="transmembrane region" description="Helical" evidence="18">
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            <end position="378"/>
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            <end position="413"/>
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            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
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            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
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            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
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            <end position="617"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="623"/>
            <end position="641"/>
        </location>
    </feature>
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        <location>
            <begin position="49"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        <source>
            <dbReference type="EMBL" id="ALN57725.1"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW26268.1"/>
        </source>
    </evidence>
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            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="668" mass="74616" checksum="27E98F9654C6485B" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DH49</accession>
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    </gene>
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        <lineage>
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        </lineage>
    </organism>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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    </dbReference>
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        <location>
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            <end position="153"/>
        </location>
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            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="ALN57865.1"/>
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    </evidence>
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            <dbReference type="EMBL" id="OPD65721.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="260" mass="28907" checksum="FA0337450704F696" modified="2016-02-17" version="1">MIDGYDTAMQGAVIEAYYGSSDFYNFGFWSADTGNQSQASEALVARLLEFIPPDRRDGRILDVACGLGASSRHLLRHFAPRQIVGINVSERQLERARHNAPGCEFRVMDATALEFPDASFDNILCVEAAFHFDTRAAFLREALRVLKPGGRLVHSDILMAPLPQTTSVRTHIPNANAMSDPAELERAILAAGFARAEVVDATEQCWTPFLRSVRRFKAAHKPPGPSTPRARRSAPIFFNPEYLARFIRRYVLACSHKSAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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        <property type="gene ID" value="GLE_2722"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="41" mass="4356" checksum="AA5B60E0EBD5F242" modified="2016-02-17" version="1">MRGLRELLQETVHDGYRETLGDGSGVGAIGRGAGRRQGSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHL7</accession>
    <name>A0A0S2DHL7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Siderophore-interacting FAD-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947683.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2620"/>
    <dbReference type="EnsemblBacteria" id="ALN57968">
        <property type="protein sequence ID" value="ALN57968"/>
        <property type="gene ID" value="GLE_2620"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2620"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2579"/>
    <dbReference type="OMA" id="VDGYWRR"/>
    <dbReference type="OrthoDB" id="1630289at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013113">
        <property type="entry name" value="FAD-bd_9_SIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007037">
        <property type="entry name" value="SIP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039374">
        <property type="entry name" value="SIP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30157">
        <property type="entry name" value="PTHR30157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08021">
        <property type="entry name" value="FAD_binding_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04954">
        <property type="entry name" value="SIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="1">
        <location>
            <begin position="5"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="282" mass="30524" checksum="76FE62A7AE67D58F" modified="2016-02-17" version="1">MSARPRARLLRVLRIAQRTARMRRITVGGRELDGFPAGSEGAHIKLFLPAEAGQTPVLPEFGEHGPVWPPGAARPAVRTYTVARIDPAAAELDIDIVLHGDDGPASRWAAAARPGDALGVAGPGGPALFRAQAGRHLLVGDPSSYALICAVIAQLPAHARIDALLEAPDAGEIQPLPAHPRLQARWFSRDGAPAGASRRLLEAVRELPWHDCETVSATLAGESAQVVAIRDLLARERGVPRAMMYAVPYWKDRWDEERYHDERHRIMDEFEAQADALQGASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHS8</accession>
    <name>A0A0S2DHS8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_13830</name>
        <name evidence="3" type="ORF">GLE_2769</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58117">
        <property type="protein sequence ID" value="ALN58117"/>
        <property type="gene ID" value="GLE_2769"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2769"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2726"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="81"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="190" mass="20669" checksum="0E03CBCAB72F1EA1" modified="2016-02-17" version="1">MQDAQDLKRLAADLAVFAQHLQEQSERAVQHVDRSADELHRAAIGMGAGAQELAQQLIGVVQNQAHEAIGRGVEQAFGSAGAQLRESVELTQRAAKALEDQRMALERSQQILLYKAVLALLVGSILAVGGSWFYIHKSMREIQRADFARDIVEATRNGALTRCDGALCARAGGKRVGPKGEYVLLEEPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHU5</accession>
    <name>A0A0S2DHU5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fe-S cluster assembly protein HesB</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Iron-sulfur cluster assembly accessory protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Iron-sulfur cluster assembly protein IscA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">iscA</name>
        <name evidence="4" type="ORF">BV903_18695</name>
        <name evidence="6" type="ORF">D9T17_15365</name>
        <name evidence="5" type="ORF">FE772_13300</name>
        <name evidence="3" type="ORF">GLE_2654</name>
    </gene>
    <organism evidence="3 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">C3</strain>
        </source>
    </reference>
    <reference evidence="4 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">OH11</strain>
        </source>
    </reference>
    <reference evidence="5 10" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 10">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HesB/IscA family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000052">
        <property type="protein sequence ID" value="OPD62385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000037">
        <property type="protein sequence ID" value="ROU06070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947706.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000037.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2654"/>
    <dbReference type="EnsemblBacteria" id="ALN58002">
        <property type="protein sequence ID" value="ALN58002"/>
        <property type="gene ID" value="GLE_2654"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62385">
        <property type="protein sequence ID" value="OPD62385"/>
        <property type="gene ID" value="BV903_18695"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2654"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2613"/>
    <dbReference type="OMA" id="GYQYGMA"/>
    <dbReference type="OrthoDB" id="1891602at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="FeS_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="FeS_cluster_insertion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017870">
        <property type="entry name" value="FeS_cluster_insertion_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="SSF89360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00049">
        <property type="entry name" value="TIGR00049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01152">
        <property type="entry name" value="HESB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-S_biosyn" evidence="2">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD62385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW26495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROU06070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="112" mass="11960" checksum="9AAC0D897DC335F1" modified="2016-02-17" version="1">MAVTLAPAALARVQHFLTETPAALGLRFGVTRTGCSGWQHVADLAREQREGDTVFEQDGVRIFVDAVSLPLVEGTRIDFLKQGLGEMFVFQNPNATAECGCGESFTTSADAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHZ6</accession>
    <name>A0A0S2DHZ6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_14615</name>
        <name evidence="2" type="ORF">GLE_2930</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58278">
        <property type="protein sequence ID" value="ALN58278"/>
        <property type="gene ID" value="GLE_2930"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2930"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2892"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="103" mass="10827" checksum="8CAB3649BB827DF0" modified="2016-02-17" version="1">MPKPKPGPGPGPELSPKLVLELVLELGAASAMPVRSHTPQPSFRRKPEPILIFAFPAGRAKATAKSKWVPAFAGMTEVQEAANLSGAGTQQRSIQARNDSGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI72</accession>
    <name>A0A0S2DI72_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heme ABC exporter, ATP-binding protein CcmA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ccmA</name>
        <name evidence="6" type="ORF">GLE_2826</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2826"/>
    <dbReference type="EnsemblBacteria" id="ALN58174">
        <property type="protein sequence ID" value="ALN58174"/>
        <property type="gene ID" value="GLE_2826"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2826"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2784"/>
    <dbReference type="OMA" id="GITHLPF"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015439">
        <property type="term" value="F:ABC-type heme transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005895">
        <property type="entry name" value="ABC_transptr_haem_export_CcmA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43499">
        <property type="entry name" value="PTHR43499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01189">
        <property type="entry name" value="ccmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="2"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="204" mass="21759" checksum="E186361F85C66872" modified="2016-02-17" version="1">MLYARGLRFARNDEPVFGPLEFAVEAGEALLVQGDNGAGKTTLLRVLAGLLRADHGEVALQGQPADPARRARAIAYLGHLPGLKADLSALENLDFLCGLHGRRPSQDAAGALATVGLAGYEDALARQLSAGQKKRLSLARLWMSPAPLWLLDEPYANLDLEGIELVNRMVQAHLREGGAALVTTHGAYAAPPVRTRLLVMEKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIE5</accession>
    <name>A0A0S2DIE5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Soluble aldose sugar dehydrogenase YliI</fullName>
            <ecNumber evidence="3">1.1.5.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">yliI</name>
        <name evidence="3" type="ORF">GLE_3075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.5.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948024.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3075"/>
    <dbReference type="EnsemblBacteria" id="ALN58422">
        <property type="protein sequence ID" value="ALN58422"/>
        <property type="gene ID" value="GLE_3075"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3075"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3035"/>
    <dbReference type="OrthoDB" id="567019at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012938">
        <property type="entry name" value="Glc/Sorbosone_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07995">
        <property type="entry name" value="GSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595074" evidence="1">
        <location>
            <begin position="23"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="GSDH" evidence="2">
        <location>
            <begin position="62"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="398" mass="42479" checksum="2C6D4FB8E45204D7" modified="2016-02-17" version="1">MTFDLRRGALAAALLLSLAACQQGNDAAAAAAAPKPAPTQATIHAVPSELGELQVTEVASGLEHPWAVALLPDGGFLVTERPGRLRRVGADGAISAPLKNVPEVWAQGQGGLLDVVLAPDFANSQRIYLSYAEPGPDDSAGTAVATATLGADALSDVKRIYQQQPKLVGPNHFGSRIAFDGKGHVFITQGERQQRMASQELDKLQGKLVRLNLDGSVPADNPFVGRNDARAEIWSYGHRNMQSLAIDPRTGTVWEAEHGPRGGDEINLPQAGKNYGWPIVTHGIDYSGLKIAEAEGKEKPGMEPPYHVWEKSPALSGMAFYTGHAGSGWNDSLFLGALSDGSLIRLSLDGDKIVGEERLLKPLGWRIRDVRVSADGKVYALTDDSDGKLLRIEPPKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIJ9</accession>
    <name>A0A0S2DIJ9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metal-dependent phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3014</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58362">
        <property type="protein sequence ID" value="ALN58362"/>
        <property type="gene ID" value="GLE_3014"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3014"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2975"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="61"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="201" mass="21306" checksum="7DAE7FB1FAA02B83" modified="2016-02-17" version="1">MGAGPVDTLAGIAPVLRQDGFPAIEVRMFPADAAEALDLIRSLGAPVRLQRHVELVGEAGEALLAVLREQGIVVDETFVRVGIVLHDAGKIRHPAELQGPGSEHEPAGEAMLLAAGVAPELARVCRSHARWAAMDCRLEELAVALADKLWKGARRGELEERFIDAAAAAGATDRWALFVALDSAFERIAAGGPTRLARSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIV6</accession>
    <name>A0A0S2DIV6_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rluF</name>
        <name evidence="6" type="ORF">FE772_15465</name>
        <name evidence="5" type="ORF">GLE_3104</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948045.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3104"/>
    <dbReference type="EnsemblBacteria" id="ALN58451">
        <property type="protein sequence ID" value="ALN58451"/>
        <property type="gene ID" value="GLE_3104"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3104"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3062"/>
    <dbReference type="OMA" id="NAHDKEY"/>
    <dbReference type="OrthoDB" id="1037615at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
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        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00093">
        <property type="entry name" value="TIGR00093"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW26833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="237" mass="26486" checksum="C583680FE78CA6F0" modified="2016-02-17" version="1">MRLNKHISDTGFCSRREADRLIAEGRVTVNGVRGRVGSEVGEGDEVRVDGDVLRVRVAAKGKRQHVYIALNKPVGVVCTTESGVKDNIVDFVGHERRIFPIGRLDKDSEGLILLTSNGDIVNEILRAENKLEKEYLVAVNHEVTPEFLRGMGRGVPIHGQTTLPCKTGKLGRFGFRIVLVQGLNRQIRLMAAHFGFRVKQLLRARIGNVKLGRLKPGQWRNLTDAELQGLLPQRTQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIW8</accession>
    <name>A0A0S2DIW8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3235</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58581">
        <property type="protein sequence ID" value="ALN58581"/>
        <property type="gene ID" value="GLE_3235"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3235"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3188"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="115" mass="11863" checksum="CECFB77CB73EAB79" modified="2016-02-17" version="1">MAHSLLARFLAELDACADAIDAALHFDDRAAVKPGYDRLMRVAAASRDRWPRPPCACASARTADADACREAVAAAEAVAAVLDGMSAGVSSYQGLAGELARARARLAAALAPPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJ51</accession>
    <name>A0A0S2DJ51_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_15420</name>
        <name evidence="1" type="ORF">GLE_3094</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948036.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58441">
        <property type="protein sequence ID" value="ALN58441"/>
        <property type="gene ID" value="GLE_3094"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3094"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3052"/>
    <dbReference type="OrthoDB" id="2152710at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="145" mass="15939" checksum="8CA1A1B45E60D651" modified="2016-02-17" version="1">MFYIGLSAQPHPDAVAAAFAAHAPQARLRWGEFDDDCAGVVFVQLHRNASEFPFALHATNLAGGDDYELGLAIARTLSLALDCRSVCDGTRHGPTQAPGWCVVWDRGQAYLGDDYHSRFYDDSPDLSADERAQLGPIRILHRLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJD1</accession>
    <name>A0A0S2DJD1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Delta-60 repeat domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948176.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3281"/>
    <dbReference type="EnsemblBacteria" id="ALN58627">
        <property type="protein sequence ID" value="ALN58627"/>
        <property type="gene ID" value="GLE_3281"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3281"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3233"/>
    <dbReference type="OMA" id="QPDGKWI"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013431">
        <property type="entry name" value="Delta_60_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17164">
        <property type="entry name" value="DUF5122"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02608">
        <property type="entry name" value="delta_60_rpt"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595235" evidence="1">
        <location>
            <begin position="28"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="531" mass="54737" checksum="2552326DC1DC6626" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJK6</accession>
    <name>A0A0S2DJK6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase, M56 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">GLE_3370</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948246.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3370"/>
    <dbReference type="EnsemblBacteria" id="ALN58716">
        <property type="protein sequence ID" value="ALN58716"/>
        <property type="gene ID" value="GLE_3370"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3370"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3320"/>
    <dbReference type="OMA" id="GDLWLGW"/>
    <dbReference type="OrthoDB" id="1585536at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008756">
        <property type="entry name" value="Peptidase_M56"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05569">
        <property type="entry name" value="Peptidase_M56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M56" evidence="3">
        <location>
            <begin position="14"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="505"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="408"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="505"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="656"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="685"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="776" mass="83917" checksum="D8DD2E80370DAB36" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJL2</accession>
    <name>A0A0S2DJL2_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Lipid-A-disaccharide synthase</fullName>
            <ecNumber evidence="3 11">2.4.1.182</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11 12" type="primary">lpxB</name>
        <name evidence="13" type="ORF">FE772_16700</name>
        <name evidence="12" type="ORF">GLE_3384</name>
    </gene>
    <organism evidence="12 14">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 14" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 14">C3</strain>
        </source>
    </reference>
    <reference evidence="13 15" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a lipid X + a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine = a lipid A disaccharide + H(+) + UDP</text>
            <dbReference type="Rhea" id="RHEA:67828"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:137748"/>
            <dbReference type="ChEBI" id="CHEBI:176338"/>
            <dbReference type="ChEBI" id="CHEBI:176343"/>
            <dbReference type="EC" id="2.4.1.182"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="11">Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the LpxB family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.182" evidence="3 11"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3384"/>
    <dbReference type="EnsemblBacteria" id="ALN58730">
        <property type="protein sequence ID" value="ALN58730"/>
        <property type="gene ID" value="GLE_3384"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3384"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3334"/>
    <dbReference type="OMA" id="PTVWAWR"/>
    <dbReference type="UniPathway" id="UPA00973"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008915">
        <property type="term" value="F:lipid-A-disaccharide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00392">
        <property type="entry name" value="LpxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003835">
        <property type="entry name" value="Glyco_trans_19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30372">
        <property type="entry name" value="PTHR30372"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02684">
        <property type="entry name" value="LpxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00215">
        <property type="entry name" value="lpxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 11" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="5 11" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11 12" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN58730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="QCW27037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="413" mass="44631" checksum="6B4EF1B9D774BD60" modified="2016-02-17" version="1">MNAPAPAPIAAAIDQIFPAGPPPPPRFALIAGEASGDLLGAGLIEELRRRHPGAEFVGIGGEQMRAAGMDTWFDAGELAVMGLSEVLKHLPRLLRLRRDVRQRILDWKPDAFIGIDAPDFNLGVERWLKQRGVRTVHYVSPSVWAWRRKRAQKIGRSADRVLCLFPMEPPIYAEYGVDARFVGHPLADEMPIHPDRDGARMTLGLDDEAPILAMLPGSRVGEIETLAADFIAAAAVLLAAEPRLGIVAPMASARARSAFERILDAHPDGARVRRALRIVDRGARTVMVASDAVLLASGTATLEAMLAKRPMAVAYKVSPLTYALVKRLGMLKVDHYALPNVLAGEPVVPELMQHDCTPENLAGAVLRWLRDPAAGAALLPKFQRIHLELKRDASARAADAIVELIGESAGATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJN8</accession>
    <name>A0A0S2DJN8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">BV903_21040</name>
        <name evidence="1" type="ORF">GLE_3275</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">B25</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000066">
        <property type="protein sequence ID" value="OPD61967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58621">
        <property type="protein sequence ID" value="ALN58621"/>
        <property type="gene ID" value="GLE_3275"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61967">
        <property type="protein sequence ID" value="OPD61967"/>
        <property type="gene ID" value="BV903_21040"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3275"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3228"/>
    <dbReference type="OrthoDB" id="1936101at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD61967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <sequence length="81" mass="8835" checksum="7C519506FCE12F21" modified="2016-02-17" version="1">MVAPSDSWLPLDEMRALGALRFGWTIDTGLAMPKLDWRAIGNDIDARGYSIVASTDVSGLLAIPQQNLPAIYPEQHRPMAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJS0</accession>
    <name>A0A0S2DJS0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">MutT/nudix family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3307</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3307"/>
    <dbReference type="EnsemblBacteria" id="ALN58653">
        <property type="protein sequence ID" value="ALN58653"/>
        <property type="gene ID" value="GLE_3307"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3307"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3257"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010710">
        <property type="entry name" value="DUF1289"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35175">
        <property type="entry name" value="PTHR35175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06945">
        <property type="entry name" value="DUF1289"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="63" mass="7236" checksum="07BEB1C9D43D60D5" modified="2016-02-17" version="1">MDDMTTFRAVLSPCIGICQLDDDGLCLGCHRTTAEIARWSQMNDDERLRLMEHVLPQRESNRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJU1</accession>
    <name>A0A0S2DJU1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8 10">Integration host factor subunit alpha</fullName>
            <shortName evidence="8">IHF-alpha</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">ihfA</name>
        <name evidence="8" type="synonym">himA</name>
        <name evidence="11" type="ORF">GLE_3563</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 10">This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8 10">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 9">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3563"/>
    <dbReference type="EnsemblBacteria" id="ALN58907">
        <property type="protein sequence ID" value="ALN58907"/>
        <property type="gene ID" value="GLE_3563"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3563"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3507"/>
    <dbReference type="OMA" id="IYVRGFG"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13835">
        <property type="entry name" value="IHF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00380">
        <property type="entry name" value="IHF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020816">
        <property type="entry name" value="Histone-like_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005684">
        <property type="entry name" value="IHF_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00987">
        <property type="entry name" value="himA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00045">
        <property type="entry name" value="HISTONE_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5 8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8 10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3 8 10" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="ALN58907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="97" mass="10922" checksum="65FF1C5BC680AABF" modified="2016-02-17" version="1">MAERLFDEVGLNKREAKEFVDAFFDALREALEQGRQVKLSGFGNFDLRRKNQRPGRNPKTGEEIPISARTVVTFRPGQKLKERVEAYSGGEHAGSGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJV0</accession>
    <name>A0A0S2DJV0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3439</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58784">
        <property type="protein sequence ID" value="ALN58784"/>
        <property type="gene ID" value="GLE_3439"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3439"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3389"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595320" evidence="1">
        <location>
            <begin position="25"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="56" mass="5940" checksum="F410DEB4090624F4" modified="2016-02-17" version="1">MSKSRFLAALAVAGLLAFATHASAQIFKPLPVPCPIGKTEKLLYDKDGKPVARVCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJZ8</accession>
    <name>A0A0S2DJZ8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3627</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58971">
        <property type="protein sequence ID" value="ALN58971"/>
        <property type="gene ID" value="GLE_3627"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3627"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3571"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="58" mass="6568" checksum="DADC3C5065BD260A" modified="2016-02-17" version="1">MSAGAWRFNRTDRPIPVIRGDGSRAMLFERHIAAITAKAVAFSIPLFAHRKEIWTESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKK8</accession>
    <name>A0A0S2DKK8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Small-conductance mechanosensitive channel</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">GLE_3699</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homoheptamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948482.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59043">
        <property type="protein sequence ID" value="ALN59043"/>
        <property type="gene ID" value="GLE_3699"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3699"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3643"/>
    <dbReference type="OMA" id="LTIRMRW"/>
    <dbReference type="OrthoDB" id="1903165at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="283"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU369025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN59043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="326" mass="34286" checksum="B53AB72E511A4F0E" modified="2016-02-17" version="1">MTGAAAASILATAAVPAAASFDWSAVRGRLLAELYRFVAAAPLLLLALLLTLAAWWFGGWLARRALIDRLAGANPFLKNLLATTLRGGCALLGLAVGLQLMNATAIVGALLGTAGVVGIALGFAFKDIIENYIAGVLLSLRQPFRPHDHVRIAEHEGLVMAMTARATVLMTLDGNQLRVPNAIVFKSVILNFSQNPSRRFEFDLSAPFDGALEATQARIRRRVEAVDGVLREPDAEVLLVSSGDGKAGVRVRGWIDQRRSDIDQVRSAALRAATAALQADAAAPAPAAAAASARPGAPERTRQHLLRAGEAGAGSRDLLDPAAPME</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKP9</accession>
    <name>A0A0S2DKP9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptidase, families S8 and S53</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_3479</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948322.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58824">
        <property type="protein sequence ID" value="ALN58824"/>
        <property type="gene ID" value="GLE_3479"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3479"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3426"/>
    <dbReference type="OrthoDB" id="923655at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase_S8" evidence="4">
        <location>
            <begin position="550"/>
            <end position="696"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN58824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="747" mass="76439" checksum="52CD5C5F73727B43" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLA7</accession>
    <name>A0A0S2DLA7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutamate methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pilK</name>
        <name evidence="4" type="ORF">GLE_3957</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3957"/>
    <dbReference type="EnsemblBacteria" id="ALN59299">
        <property type="protein sequence ID" value="ALN59299"/>
        <property type="gene ID" value="GLE_3957"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3957"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3894"/>
    <dbReference type="OrthoDB" id="1378426at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008984">
        <property type="term" value="F:protein-glutamate methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035909">
        <property type="entry name" value="CheB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000673">
        <property type="entry name" value="Sig_transdc_resp-reg_Me-estase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01339">
        <property type="entry name" value="CheB_methylest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52738">
        <property type="entry name" value="SSF52738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50122">
        <property type="entry name" value="CHEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CheB-type methylesterase" evidence="3">
        <location>
            <begin position="607"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="345"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="494"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="774" mass="79257" checksum="D6A171383AF2D3B1" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLC0</accession>
    <name>A0A0S2DLC0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948704.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59342">
        <property type="protein sequence ID" value="ALN59342"/>
        <property type="gene ID" value="GLE_4000"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4000"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3936"/>
    <dbReference type="OMA" id="GRAMGCI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022123">
        <property type="entry name" value="DUF3658"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12395">
        <property type="entry name" value="DUF3658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="107" mass="11462" checksum="E9AF54B2E7140E92" modified="2016-02-17" version="1">MSDSQYEPADAAPDEAALKRIAALRPEQLQAIDAVLMNACDGQWRKVASVVGRAMGCIPDRVPGIPDGFYAARVSGLVARGLLESQGDLSRMRYSEVRLTMKPAGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLJ7</accession>
    <name>A0A0S2DLJ7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4222</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59563">
        <property type="protein sequence ID" value="ALN59563"/>
        <property type="gene ID" value="GLE_4222"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4222"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4164"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="65" mass="7137" checksum="832D052DC9AE2E86" modified="2016-02-17" version="1">MPGRRHFRRRDSRRRARPRRASTHVRGVFETISSRIGAAGYGGPPSRGPARSGAGIGSRPPRRAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLR9</accession>
    <name>A0A0S2DLR9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">50S ribosomal subunit assembly factor BipA</fullName>
            <ecNumber evidence="3">3.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">GTP-binding protein BipA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">typA</name>
        <name evidence="3" type="synonym">bipA</name>
        <name evidence="6" type="ORF">BV903_22855</name>
        <name evidence="7" type="ORF">FE772_18470</name>
        <name evidence="5" type="ORF">GLE_3752</name>
    </gene>
    <organism evidence="5 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">C3</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">B25</strain>
        </source>
    </reference>
    <reference evidence="7 10" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="3">Binds to ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000077">
        <property type="protein sequence ID" value="OPD61584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948524.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000077.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3752"/>
    <dbReference type="EnsemblBacteria" id="ALN59096">
        <property type="protein sequence ID" value="ALN59096"/>
        <property type="gene ID" value="GLE_3752"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61584">
        <property type="protein sequence ID" value="OPD61584"/>
        <property type="gene ID" value="BV903_22855"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3752"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3696"/>
    <dbReference type="OMA" id="MSMLFTI"/>
    <dbReference type="OrthoDB" id="143460at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03710">
        <property type="entry name" value="BipA_TypA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00849">
        <property type="entry name" value="BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035651">
        <property type="entry name" value="BipA_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042116">
        <property type="entry name" value="TypA/BipA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006298">
        <property type="entry name" value="TypA_GTP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF8">
        <property type="entry name" value="PTHR42908:SF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01394">
        <property type="entry name" value="TypA_BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Tr-type G" evidence="4">
        <location>
            <begin position="4"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="16"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="135"/>
            <end position="138"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="OPD61584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW27328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="616" mass="68024" checksum="0AF4ED4AE461F47E" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLY4</accession>
    <name>A0A0S2DLY4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NAD-dependent deacylase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator, Sir2 family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_21410</name>
        <name evidence="4" type="ORF">GLE_4382</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
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    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5 7">YC36</strain>
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        <property type="gene ID" value="GLE_4382"/>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="228" mass="25348" checksum="3FCFC9AB2517CDFC" modified="2016-02-17" version="1">MKPKIVVFTGAGVSAESGLKTFRDMGGLWHEHRLEDVASPEGRRRDPATVLRFYNERRLGVLAAQPNAAHAAIARLEEKFDVVVITQNIDDLHERAGSSQVLHVHGEILKARSSADQSRVYPMTGALIEIGDLCELGSQLRPDVVWFGENVRHLRESARHFAQADKVLAIGTSLTVWPAAGLVDHARDRAERVFVSPEQQDIPDHYRFLRGTAVEKVPPLVEAWLARA</sequence>
</entry>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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            <begin position="46"/>
            <end position="66"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="98"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="110"/>
            <end position="129"/>
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            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="EMBL" id="ALN59637.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27757.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="139" mass="14270" checksum="8141E4669E3082E7" modified="2016-02-17" version="1">MQAAGPMGWGLLLLAVAVFGLAPAAWLLQARVARAVGARPAFGATLWTVLFAVVLWAMLAVAALIATHASAIGSGAPFAALAAALSWLALGVGVRLYLPDPAGAKLAWRRALWAALPAVALLWVEVVAVRRALEWGGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMH3</accession>
    <name>A0A0S2DMH3_LYSEN</name>
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        <submittedName>
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        <submittedName>
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    <gene>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="2 5" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="3 6" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">YC36</strain>
        </source>
    </reference>
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        <property type="gene ID" value="GLE_4419"/>
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        <property type="protein sequence ID" value="OPD63761"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD63761.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27855.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="142" mass="15352" checksum="B9CA4D80A7637789" modified="2016-02-17" version="1">MTDSTVPTVHARGEAAPYAVSFVDDGEHRWQADEPAEVGGGDRAPSPERLLLSSLGACTAITVRMYAERKQWPLAQVEVMLRFNPAGKPAAGTDIERHIVLRGELSEEQRERLLQIANACPIHKVLSGEVRIATALEAGAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMJ9</accession>
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        <recommendedName>
            <fullName evidence="2">Cell shape-determining protein MreB</fullName>
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    <gene>
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        <name evidence="6" type="ORF">FE772_22040</name>
        <name evidence="3" type="ORF">GLE_4513</name>
        <name evidence="4" type="ORF">LEN_0704</name>
        <name evidence="8" type="ORF">SAMN05421681_101220</name>
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    <organism evidence="3 9">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 9">C3</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="journal article" date="2016" name="DNA Res." volume="0" first="0" last="0">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer, Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">M497-1</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="3">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">ATCC 29487</strain>
        </source>
    </reference>
    <reference evidence="4 12" key="4">
        <citation type="journal article" date="2017" name="DNA Res." volume="24" first="169" last="177">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
            <dbReference type="PubMed" id="28065880"/>
            <dbReference type="DOI" id=".1093/dnares/dsw055"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 12">M497-1</strain>
        </source>
    </reference>
    <reference evidence="5 11" key="5">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 11">B25</strain>
        </source>
    </reference>
    <reference evidence="7 13" key="6">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 13">OH11</strain>
        </source>
    </reference>
    <reference evidence="6 14" key="7">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 14">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Forms polymers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="2">Membrane-associated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the FtsA/MreB family.</text>
    </comment>
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        <property type="gene ID" value="LEN_0704"/>
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        <property type="gene ID" value="SAMN05421681_101220"/>
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    <feature type="binding site" evidence="2">
        <location>
            <begin position="19"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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            <begin position="169"/>
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        </location>
        <ligand>
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    <feature type="binding site" evidence="2">
        <location>
            <begin position="217"/>
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        </location>
        <ligand>
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        </ligand>
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    <feature type="binding site" evidence="2">
        <location>
            <begin position="297"/>
            <end position="300"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAV96191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD65364.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="QCW27925.1"/>
        </source>
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            <dbReference type="EMBL" id="ROU07894.1"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
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        <source>
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        <source>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="348" mass="37449" checksum="EAE453375171E60D" modified="2016-02-17" version="1">MFKKFRGMFSNDLSIDLGTANTLIYVRGQGIVLNEPSVVAVRQDRMIGGNRTVAAVGGEAKQMLGRTPGHITTIRPMKDGVIADFTYTEEMLKHFIRKVHKSRFLRPSPRVLVCVPCGSTQVERRAIKESAEEAGAREVYLIEEPMAAAIGAGMPVTEARGSMVVDVGGGTTEVAVIALNGIVYSASVRIGGDRFDESIINYVRRTYGTLIGEATAERIKLEIGCAYPQERASTVEISGRNLAEGVPKMVTINSNEVLEALREPLSGIVSAIKLALEQTPPELCADVAERGIVLTGGGALLRDLDRLISEETGLHVQVADDPLTCVARGGGRALELVDMHGNEFFAPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMK8</accession>
    <name>A0A0S2DMK8_LYSEN</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="2" type="ORF">FE772_21415</name>
        <name evidence="1" type="ORF">GLE_4383</name>
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        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
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    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="143" mass="16017" checksum="F8EEC1AC8498E2A6" modified="2016-02-17" version="1">MLPPEYAELFDPMQFNVWVKIDPAKVMGASAWYAQRSEHAGGKSVAARYLDCRDAARRGEYVSLEWILHLRQLPDALDSVPDFAVPGSAIVSDEPIVPDAQTPFCETHGILFTARLGCSVCKDPVWHKMPPGLRERLHRGEFP</sequence>
</entry>
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    <accession>A0A0S2DML6</accession>
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        <submittedName>
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        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">FE772_21530</name>
        <name evidence="2" type="ORF">GLE_4407</name>
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    <organism evidence="2 4">
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        <dbReference type="NCBI Taxonomy" id="69"/>
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        </lineage>
    </organism>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59748.1"/>
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        <property type="gene ID" value="GLE_4407"/>
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    <dbReference type="KEGG" id="lez:GLE_4407"/>
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    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PGBD-like_sf"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF47090"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PG_binding_1" evidence="1">
        <location>
            <begin position="228"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="478" mass="51496" checksum="D652713F3015EF7A" modified="2016-02-17" version="1">MDGRTTHYRVIQLGAPKGAGGVQSNEVVSDFDSLVTHHPGNNRNAHLENGLVVGGERTRQHALIGGEIQEIEIVRNGNTFQGLKPDQVLLKKDFMLEAPGQANPRQVDVPSPVAGVVGRVSHAEGLVDIHDRQGGDVIARVRHMRDIELEVNDAVAYGQSLGTQHRVATEKVHVHMEVDTRYYRQFENYVGDLTEGRLPVEAAARLGVEPRAVADDGVLRLGESSLRIRDLQNHLNGMGYVGADGQALTADGVYRLNMQRAVLDYQREQCLPQTGDISREMLQAVPARTPGPFDPALGGIPAPGLPYAPMPHPFGTGADDRPCAPPTLQQIEDAAERRRPWDPAFSAAPPSISSDPLVQSIRERLPQAFATYGAAPPEVELDRIATGLAVECRKQGIERPDHIAVGNPATDGSGRHVFAVVGDLRDPASHRVDVAAHAAAQVPVEASLLKLDALQASTPALVQGDQAQELQKAPSMRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMN1</accession>
    <name>A0A0S2DMN1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3224 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_22375</name>
        <name evidence="1" type="ORF">GLE_4585</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949164.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59926">
        <property type="protein sequence ID" value="ALN59926"/>
        <property type="gene ID" value="GLE_4585"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4585"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4521"/>
    <dbReference type="OMA" id="GKLCGRQ"/>
    <dbReference type="OrthoDB" id="1942143at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021607">
        <property type="entry name" value="DUF3224"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023159">
        <property type="entry name" value="SO1590-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11528">
        <property type="entry name" value="DUF3224"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159238">
        <property type="entry name" value="SSF159238"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW27982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="133" mass="14141" checksum="9EEF8B4E2CC4377C" modified="2016-02-17" version="1">MPQVEGPFQVKLSPQPLHAAAEGMFGRMALDKRFEGALHADSRGEMLAATTAVPGSAGYVALEKVDGALDGRRGSFLLLHSGLMNRGQAELTIVVVPDSGSGELEGLSGRMKIDIREGGAHFYRFEYALPGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMS0</accession>
    <name>A0A0S2DMS0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4734</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60075">
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        <property type="gene ID" value="GLE_4734"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4734"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4668"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="315" mass="35398" checksum="730AE6986BA54DC7" modified="2016-02-17" version="1">MYAQCRKCKRPIAPNALRCPQCGIPMPLGGVPSVWQMWRANGTATRILFIGACMLITLLVLSMASDDVSDFIAQTSKAHNDAADSRELLLREQQRLNQPDGSERLDRPEPSAATALAPARDAKSLMQGMRIVLREVGDKSRYRQAKAQQRIEGLHLEQQLLPETLLGPKATQAARRTNREYAELLNYTLAVKQASQRELALRLRALTGEGPDGRAIMTEFQRNLARESEEDAALMKNRRAIIERIERIYDLADAHRDGIEVRDDGSLAFADPLVAEQYNRSIAEIGAFLQQSESIDVQRRARTQAALQEIDRLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMT0</accession>
    <name>A0A0S2DMT0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_23090</name>
        <name evidence="1" type="ORF">GLE_4750</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949286.1">
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60091">
        <property type="protein sequence ID" value="ALN60091"/>
        <property type="gene ID" value="GLE_4750"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4750"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4684"/>
    <dbReference type="OrthoDB" id="1878563at2"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW28101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="202" mass="22872" checksum="30F8CC980E64F45F" modified="2016-02-17" version="1">MISEQEACDRVLARFVDTRGAIASCRLDPRGEYWVIHANAYEYVVNGRSEHCLIGDGAYLVHIASGRLTITPSHETWHESIQDIYDLDDAAGAHYVLRPDYAAGDKRAIVHLHQRLGCSLIDARWLLEDANRSWLTGTGRNLRQACELLAAHGVETQRVLQDELRHALLLTPQQWTLDMMLQRLRERASLRSAVVPLRDAIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN38</accession>
    <name>A0A0S2DN38_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
    <gene>
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    <organism evidence="1 2">
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        <lineage>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59956">
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        <property type="gene ID" value="GLE_4615"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4615"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4550"/>
    <dbReference type="Proteomes" id="UP000061569">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="50" mass="6333" checksum="CD52350AD7B91BAD" modified="2016-02-17" version="1">MERRIVRCARARAKSKYFARKIFLISFDKIYYEYSGCILRRTMWHKYRIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN39</accession>
    <name>A0A0S2DN39_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_21935</name>
        <name evidence="2" type="ORF">GLE_4492</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949096.1">
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59833">
        <property type="protein sequence ID" value="ALN59833"/>
        <property type="gene ID" value="GLE_4492"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4492"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4429"/>
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    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
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        <location>
            <begin position="19"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="150" mass="16712" checksum="B06EA647E1FAA75B" modified="2016-02-17" version="1">MRWLAVVALSIFSPAAFALSIVCADRGYPKELPDPIRYEVSEHPATDADDAKTEVEYFVLLAKQVDGKDLDVARMEVLDGDEVVLSTGLRTHAHEVLGWGDTYFAVVRTTDTRRRIRIVATYDPVCRVTLRQTLSQDHVDADAEPAPGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN58</accession>
    <name>A0A0S2DN58_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CRP-like protein Clp</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Catabolite activation-like protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">GLE_4661</name>
    </gene>
    <organism evidence="12 13">
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        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">C3</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4661"/>
    <dbReference type="EnsemblBacteria" id="ALN60002">
        <property type="protein sequence ID" value="ALN60002"/>
        <property type="gene ID" value="GLE_4661"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4661"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4597"/>
    <dbReference type="OMA" id="EFQRRGW"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="6" id="KW-0973">c-di-GMP</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="7" id="KW-0843">Virulence</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="10">
        <location>
            <begin position="38"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="HTH crp-type" evidence="11">
        <location>
            <begin position="171"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN60002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="272" mass="30428" checksum="6B92597CDAB04B8B" modified="2016-02-17" version="1">MRGSAGRRAVRAAGRMALSAADGAAVRRRRWGLDRCALLRGLPVTLLEHIARHSSEANLEEGDTLFFKNDPSDCLAFVVHGRIYKLLYGPDGQELIVDTIESGETVDETPLLDTHAHTFTAVAYSPTRVLLLPRRHFPSLTNDPVVIERAHASLCLRLRQAVESLETMCLHRLESRLARYLLSLMHNQPQPRGGDFEVALPPTQSILAAMVNASRPKLNAQLQTWHRSGLVSRKRNILRINDIDQFRCKAYLGRDFERPGGRARAGSAWRNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNF2</accession>
    <name>A0A0S2DNF2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">LysE family translocator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Translocator protein, LysE family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FE772_22335</name>
        <name evidence="6" type="ORF">GLE_4576</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949156.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4576"/>
    <dbReference type="EnsemblBacteria" id="ALN59917">
        <property type="protein sequence ID" value="ALN59917"/>
        <property type="gene ID" value="GLE_4576"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4576"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4512"/>
    <dbReference type="OMA" id="YMFCAAF"/>
    <dbReference type="OrthoDB" id="1927576at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006324">
        <property type="entry name" value="LeuE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="154"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN59917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW27976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="209" mass="22322" checksum="FDA56EB323016E17" modified="2016-02-17" version="1">MIEPSSLLAFAGLALVMVLTPGPNMVYLVSRSICQGRRAGWTSLAGVAVGFVFYLLAAAFGITALLFAVPYAYDALRFGGALYLLWLAWQAIKPGGRSPFQVRELAPDSPRRLFAMGLLTSLLNPKVAVFYLALLPQFIDPARSVMPQSLLLGAVQICISVGVNALIVAAAGTIAAFLAGRPRWIAAQRWVMGGVLSALALRMAVDSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNG1</accession>
    <name>A0A0S2DNG1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4773</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949304.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4773"/>
    <dbReference type="EnsemblBacteria" id="ALN60114">
        <property type="protein sequence ID" value="ALN60114"/>
        <property type="gene ID" value="GLE_4773"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4773"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4707"/>
    <dbReference type="OMA" id="LTRPDCR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="7"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="293" mass="31073" checksum="7BC25B55A9B9A381" modified="2016-02-17" version="1">MRQTARLSLEDFELLRAIGAHGSLSGAAKALALDHSSAFRRLAGIEARAGTPLFRRSRTGYTATEAGAVAIEGAQRILDDADQLQRQLAGRDARGGARLRITIPDTLADVAARLCAAFAAAHPQIGCDLLVSNAFVNLQQPEADVALRACALMPSGLSVRRVGSIATAVYAASGAKLGKREALSEGAWVGFDDNLSHLSSALWLRANVDEARIAMRVNSLPAALAACKAGVGKALLPCYFADAAGGVKRVSQPLTEVPTELWFAIHPDLRRSARVRALREFALGWLPREMALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP14</accession>
    <name>A0A0S2DP14_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4977</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949457.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4977"/>
    <dbReference type="EnsemblBacteria" id="ALN60318">
        <property type="protein sequence ID" value="ALN60318"/>
        <property type="gene ID" value="GLE_4977"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4977"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4904"/>
    <dbReference type="OMA" id="AWWFARS"/>
    <dbReference type="OrthoDB" id="1580783at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="236" mass="25853" checksum="A6A91DBB6E06F7BF" modified="2016-02-17" version="1">MNEAASSVSGPARVALAVAYPLLAHWASHDGGGALAALALADLVVFVVLDGLLALRPAPWAIAAALLAALAALARTPYAQMLLLTPPVLFNAWLAWWFARSLRAPREGLITRIVAALHDCAPRDLDPPLYRYTRSLTALWAWTMALLTAANAALALIAVPDGLLARLGYLPSPSITQEQWSWFANIINYGVLGAMFAGEYLVRRQRFPERPESGFFDFLRRMARLGPRFWKELFST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP32</accession>
    <name>A0A0S2DP32_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4796</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4796"/>
    <dbReference type="EnsemblBacteria" id="ALN60137">
        <property type="protein sequence ID" value="ALN60137"/>
        <property type="gene ID" value="GLE_4796"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4796"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4729"/>
    <dbReference type="OMA" id="TWNEAIV"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595046" evidence="1">
        <location>
            <begin position="25"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="203" mass="22333" checksum="7A97EC1A70D176C4" modified="2016-02-17" version="1">MPPMKSFFLASVVTLMTVSTAACQQPVPPPQVKANPNPQHKYEVVMTVRNAPRAFEQVAGSAQFDIPAEQDACLPLDQTRALAGVRNRPSETVPLQFRKVSDTEYRAEFFADALLDEDYYGLGVCHWKLTAVGATLTAQPAVFSTETWNEAIVSGAQQVTFAPKSLFSLSPDPIEFHPMTLAGERAPSAEDFEVVFQSRKIEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP42</accession>
    <name>A0A0S2DP42_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_4870</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60211">
        <property type="protein sequence ID" value="ALN60211"/>
        <property type="gene ID" value="GLE_4870"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4870"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4801"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="105" mass="12482" checksum="550AEDA7AA0836AE" modified="2016-02-17" version="1">MDFVRANRQCVTTHPVHYSSRCTCGSFRDIPRRVSVLHLPKYRMVARGIRRRPIPRPRMKRRIRRIAPSARRRRRGTRRKSLAMRRGANAAIAVLQSIRRRRRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPJ6</accession>
    <name>A0A0S2DPJ6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rhodanese domain protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Rhodanese-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_24395</name>
        <name evidence="3" type="ORF">GLE_5032</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949502.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5032"/>
    <dbReference type="EnsemblBacteria" id="ALN60373">
        <property type="protein sequence ID" value="ALN60373"/>
        <property type="gene ID" value="GLE_5032"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5032"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4960"/>
    <dbReference type="OMA" id="HKAQPVI"/>
    <dbReference type="OrthoDB" id="2056793at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="52"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="145" mass="15883" checksum="9A8FBC24C9357BEA" modified="2016-02-17" version="1">MSFDELLAFAGRHLYLSLGLVGLTLALIYTETARLFRGYKALRPAELTQMINRDNALVIDLSAIGEFEKGHIPGSRSVQPSQFDPESKLLANAKQLPVVAVCRNGQASADAAKRLKKAGFEKVYWLDGGIAAWQQAELPLVKGRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPK9</accession>
    <name>A0A0S2DPK9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphogluconate dehydratase</fullName>
            <ecNumber evidence="6">4.2.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 7" type="primary">edd</name>
        <name evidence="8" type="ORF">FE772_25145</name>
        <name evidence="7" type="ORF">GLE_5191</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>6-phospho-D-gluconate = 2-dehydro-3-deoxy-6-phospho-D-gluconate + H2O</text>
            <dbReference type="Rhea" id="RHEA:17277"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57569"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="4.2.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Carbohydrate metabolism; Entner-Doudoroff pathway.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the IlvD/Edd family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.12" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949622.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5191"/>
    <dbReference type="EnsemblBacteria" id="ALN60532">
        <property type="protein sequence ID" value="ALN60532"/>
        <property type="gene ID" value="GLE_5191"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5191"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5111"/>
    <dbReference type="OMA" id="CANIAHV"/>
    <dbReference type="OrthoDB" id="193579at2"/>
    <dbReference type="UniPathway" id="UPA00226"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004456">
        <property type="term" value="F:phosphogluconate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046177">
        <property type="term" value="P:D-gluconate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009255">
        <property type="term" value="P:Entner-Doudoroff pathway through 6-phosphogluconate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02094">
        <property type="entry name" value="Edd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004786">
        <property type="entry name" value="6-phosphgluc_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042096">
        <property type="entry name" value="Dihydro-acid_dehy_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000581">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020558">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037237">
        <property type="entry name" value="IlvD/EDD_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43661:SF1">
        <property type="entry name" value="PTHR43661:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00920">
        <property type="entry name" value="ILVD_EDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143975">
        <property type="entry name" value="SSF143975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01196">
        <property type="entry name" value="edd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00886">
        <property type="entry name" value="ILVD_EDD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00887">
        <property type="entry name" value="ILVD_EDD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5 6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 6" id="KW-0311">Gluconate utilization</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 6 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN60532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW28450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="610" mass="64639" checksum="E4CE10E548A1E14A" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPM4</accession>
    <name>A0A0S2DPM4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RDD family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="9">RDD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">BV903_12235</name>
        <name evidence="10" type="ORF">FE772_24265</name>
        <name evidence="8" type="ORF">GLE_5004</name>
    </gene>
    <organism evidence="8 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">C3</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">B25</strain>
        </source>
    </reference>
    <reference evidence="10 13" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000029">
        <property type="protein sequence ID" value="OPD63684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949479.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000029.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60345">
        <property type="protein sequence ID" value="ALN60345"/>
        <property type="gene ID" value="GLE_5004"/>
    </dbReference>
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        <property type="protein sequence ID" value="OPD63684"/>
        <property type="gene ID" value="BV903_12235"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5004"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4932"/>
    <dbReference type="OMA" id="PAEVWRI"/>
    <dbReference type="OrthoDB" id="1974702at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010432">
        <property type="entry name" value="RDD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06271">
        <property type="entry name" value="RDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="RDD" evidence="7">
        <location>
            <begin position="29"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN60345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="OPD63684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW28297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="168" mass="18242" checksum="027EAF490CF1D5EC" modified="2016-02-17" version="1">MEDTQNPYAAPTAPPPLPGELVDDSVKADRGLRLVARLIDGALMMVCFVPTFLAIAIDPGNKEPSGLQMAMMALSVLAALGLFVYQCVLLNQHSQTLGKRWLKIKIVRNDGSPCSFGRIFGLRMFVIALIEQVPCLGALFALVNALWIFGAESRCLHDLICDTKVVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPZ7</accession>
    <name>A0A0S2DPZ7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyl carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_12120</name>
        <name evidence="6" type="ORF">D9T17_04685</name>
        <name evidence="5" type="ORF">FE772_24130</name>
        <name evidence="3" type="ORF">GLE_4978</name>
    </gene>
    <organism evidence="3 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">C3</strain>
        </source>
    </reference>
    <reference evidence="4 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">OH11</strain>
        </source>
    </reference>
    <reference evidence="5 10" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 10">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000029">
        <property type="protein sequence ID" value="OPD63663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000013">
        <property type="protein sequence ID" value="ROU08373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949458.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4978"/>
    <dbReference type="EnsemblBacteria" id="ALN60319">
        <property type="protein sequence ID" value="ALN60319"/>
        <property type="gene ID" value="GLE_4978"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD63663">
        <property type="protein sequence ID" value="OPD63663"/>
        <property type="gene ID" value="BV903_12120"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4978"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4905"/>
    <dbReference type="OMA" id="DNLARTH"/>
    <dbReference type="OrthoDB" id="1943389at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="2">
        <location>
            <begin position="5"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="1">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD63663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW28274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ROU08373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="89" mass="9891" checksum="D1F2F983E73AA365" modified="2016-02-17" version="1">MSEQSPAERELAQLLVESLNLEDVAPEQIDPDAALFNDGLGLDSIDALELALAITKRYGFQLRSDNDENRRIFASLRALSSHIEQHRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ02</accession>
    <name>A0A0S2DQ02_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">6-phosphogluconolactonase</fullName>
            <shortName evidence="7">6PGL</shortName>
            <ecNumber evidence="5 7">3.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">pgl</name>
        <name evidence="9" type="ORF">GLE_5192</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12556"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="3.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.31" evidence="5 7"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5192"/>
    <dbReference type="EnsemblBacteria" id="ALN60533">
        <property type="protein sequence ID" value="ALN60533"/>
        <property type="gene ID" value="GLE_5192"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5192"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5112"/>
    <dbReference type="OMA" id="YQLFEFE"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00409"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01400">
        <property type="entry name" value="6PGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005900">
        <property type="entry name" value="6-phosphogluconolactonase_DevB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039104">
        <property type="entry name" value="PGLS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11054">
        <property type="entry name" value="PTHR11054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01198">
        <property type="entry name" value="pgl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine_iso" evidence="8">
        <location>
            <begin position="25"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN60533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="251" mass="27501" checksum="0F0435D7ED95DCC6" modified="2016-02-17" version="1">MKMQAERLTVIEPLPLPLHEKLFDDGEQLALALARQVAADLRAALARHGEASIALSGGNTPKRFFQLLSQQTLDWARVTVLPIDERWVPAEHPRSNERLLREHLFQNNAAVARFLPLYRPVDTPEMALMPVLTKIANEGLPLDVAVLGMGEDGHTASLFPDLGHDNPALREIGLQPRGRAPVMSVRTAAMPEPRMTLTLSAIFTAPALYLHIEGESKRAVLDAARSDPRSTLPIRAALAGASNAPTLYWSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ14</accession>
    <name>A0A0S2DQ14_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RDD family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">RDD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_24950</name>
        <name evidence="7" type="ORF">GLE_5148</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949590.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60489">
        <property type="protein sequence ID" value="ALN60489"/>
        <property type="gene ID" value="GLE_5148"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5148"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5072"/>
    <dbReference type="OMA" id="RGWHDSI"/>
    <dbReference type="OrthoDB" id="1974702at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010432">
        <property type="entry name" value="RDD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06271">
        <property type="entry name" value="RDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="RDD" evidence="6">
        <location>
            <begin position="26"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN60489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW28416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="163" mass="17994" checksum="E5D6D84B7A93329B" modified="2016-02-17" version="1">MNEPHDPYTAPQAQIRAERAAQLVVAGRIQRLVNYLIDSTACVALIFCGLSVYSAIDPGVIETLKQPDPLRDLAMTALVLLVYYVPMEGMFGVTLGKLVTNTRVVDEQGRPPSWGQVLARTVARLIPFEQFTILFSPAARPTAWHDRLPKTLVVRAQPTPASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ52</accession>
    <name>A0A0S2DQ52_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase sigma factor, sigma-70 family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Sigma-70 family RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_25490</name>
        <name evidence="4" type="ORF">GLE_5270</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949681.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5270"/>
    <dbReference type="EnsemblBacteria" id="ALN60611">
        <property type="protein sequence ID" value="ALN60611"/>
        <property type="gene ID" value="GLE_5270"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5270"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5189"/>
    <dbReference type="OMA" id="IRWMGAD"/>
    <dbReference type="OrthoDB" id="1335404at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="9"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="114"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW28502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="300" mass="32851" checksum="B33B32050E196F67" modified="2016-02-17" version="1">MTAAHDDRLFAQHAPMLTGLAYRILGSRADAEDAVQDTYLKWREAGREAINNPAAWLTTACTRRCIDLLRAAHRTRVDYVGSWLPEPIQAEFAEAGGDGGPEAHWTLASSLSTAFLLLLERLTPKERAAYLLHEIFDQPYAEVASILEIEEAACRKLVQRARGNIEQAKVRHVTPAEQQDRLLAAFETAIVQGRTAPLASLLSQQIALHADGGGKATAAAQAIHGADAVLGFIASVLHPACREDRWTFVDLNGSRGVILERAGRIEAAISFGYEEGGALRDIFIMRNPDKLARLEAVRIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ77</accession>
    <name>A0A0S2DQ77_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Isocitrate dehydrogenase kinase/phosphatase</fullName>
            <shortName evidence="4">IDH kinase/phosphatase</shortName>
            <shortName evidence="4">IDHK/P</shortName>
            <ecNumber evidence="4">2.7.11.5</ecNumber>
            <ecNumber evidence="4">3.1.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 5" type="primary">aceK</name>
        <name evidence="6" type="ORF">FE772_00170</name>
        <name evidence="5" type="ORF">GLE_5377</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>ATP + L-seryl-[isocitrate dehydrogenase] = ADP + H(+) + O-phospho-L-seryl-[isocitrate dehydrogenase]</text>
            <dbReference type="Rhea" id="RHEA:43540"/>
            <dbReference type="Rhea" id="RHEA-COMP:10605"/>
            <dbReference type="Rhea" id="RHEA-COMP:10606"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.5"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the AceK family.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.5" evidence="4"/>
    <dbReference type="EC" id="3.1.3.-" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949760.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5377"/>
    <dbReference type="EnsemblBacteria" id="ALN60718">
        <property type="protein sequence ID" value="ALN60718"/>
        <property type="gene ID" value="GLE_5377"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5377"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5292"/>
    <dbReference type="OMA" id="EPWYSVG"/>
    <dbReference type="OrthoDB" id="245269at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008772">
        <property type="term" value="F:[isocitrate dehydrogenase (NADP+)] kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00747">
        <property type="entry name" value="AceK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010452">
        <property type="entry name" value="Isocitrate_DH_AceK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39559">
        <property type="entry name" value="PTHR39559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06315">
        <property type="entry name" value="AceK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000719">
        <property type="entry name" value="AceK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 4" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="active site" evidence="4">
        <location>
            <position position="377"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="321"/>
            <end position="327"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW24313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="576" mass="65371" checksum="9650D852B38B33A1" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQA1</accession>
    <name>A0A0S2DQA1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">ABC transporter, ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FE772_00080</name>
        <name evidence="6" type="ORF">GLE_5357</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5357"/>
    <dbReference type="EnsemblBacteria" id="ALN60698">
        <property type="protein sequence ID" value="ALN60698"/>
        <property type="gene ID" value="GLE_5357"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5357"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5272"/>
    <dbReference type="OMA" id="QGNGAGH"/>
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    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="33"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="66"/>
            <end position="73"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN60698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW24297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="340" mass="36999" checksum="D6CB698264F590B7" modified="2016-02-17" version="1">MTQPTALATGPRPATSGTATVGTPARADAVPALRVRDLRKTYDNKVEALKGVSLDVAEGDFFALLGPNGAGKSTLIGIVSSLVNLSDGAVEIFGTDLQRRRDQAMRLIGLVPQEINFNMFEKPLDILVNYAGFYGVPREQALARAEEELKRAQLWDKADKMSRTLSGGMKRRLMIARAMMTRPRLLILDEPTAGVDIEIRRGMWKTLREINAAGTTIILTTHYLEEAESLCRNLAIIDQGRIVQQGPMKALLAMLDVEGFLLDIDGTLPAALPYIEGAALAAADDHTLDLEMPRAMDLNRVFAALGEAGIRVRSMRTKSNRLEELFVRMIAQPSAAGSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQA9</accession>
    <name>A0A0S2DQA9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">MFS transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Transporter, major facilitator family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_00040</name>
        <name evidence="7" type="ORF">GLE_5347</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949739.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60688">
        <property type="protein sequence ID" value="ALN60688"/>
        <property type="gene ID" value="GLE_5347"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5347"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5263"/>
    <dbReference type="OMA" id="LGTWIGQ"/>
    <dbReference type="OrthoDB" id="1384345at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="203"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="233"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="268"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="291"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="327"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="360"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="4"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN60688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW24292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="400" mass="40694" checksum="7306D4866B76C767" modified="2016-02-17" version="1">MPLALLALTLGAFAIGTTEFVIVGLIPTLAADLGVDLPSAGLLVSLYALAVALGAPLLTALTGRVPRKALLVGLMALFTVGNVVAWLAPGYATLVVARVLTGLAHGVFFSVGSIIATSLVPKEKAASAIATMFSGMTVAFVTGIPLGTFLGQHFGWRSTFLAVAGFGLIALAGSALFVPRRIAHAAPAPLRQQAALLLQPRLLLVYAMTAVGYGGSLIAFTFLAPILQDIAGLGPNLVGAVLLAYGVSVAVGNVWGGRLADRHGPVKALKTIFALLAAVLLALTFTAHSPWLVVLTALAWGAVAFGNVPGLQVYVVKQAQRYAPQAVDTAAGFNIAAFNLGVAGGAWAGGQVVAHLGLAHTPWIAALVVFAAFGLTALSGRLDRRDGVADRADGLAVAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQH5</accession>
    <name>A0A0S2DQH5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transmembrane regulator PrtR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">prtR</name>
        <name evidence="2" type="ORF">GLE_5202</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949630.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5202"/>
    <dbReference type="EnsemblBacteria" id="ALN60543">
        <property type="protein sequence ID" value="ALN60543"/>
        <property type="gene ID" value="GLE_5202"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5202"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5121"/>
    <dbReference type="OMA" id="NVFYWID"/>
    <dbReference type="OrthoDB" id="1494577at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="251" mass="27123" checksum="4025733B7482C9D4" modified="2016-02-17" version="1">MTHVPDEHDLHAYIDGRLDPARRAEVEAWLARQPERLAELQAWQRDAQQLRAALAGAAPAPEPALDPARLRAGLARRRSARYAFAAALLLSLGVGGIGGWQAREWSRPAPSATLAAAPMADAIAAHRLFAARGELRADTVANDVQPWLDANFREPMRLPDLSAAGYRPVGARLLATDQGAAALVVYQHAGGEAISFYIRPPGPRHHLLPRGDRRDGGLLAQYWSRGGYNYAMVSAGDDASARVVRQALQAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQK8</accession>
    <name>A0A0S2DQK8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5509</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DR37</accession>
    <name>A0A0S2DR37_LYSEN</name>
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        <submittedName>
            <fullName evidence="8">Amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">GLE_5307</name>
    </gene>
    <organism evidence="8 9">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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    </dbReference>
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    </dbReference>
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            <end position="79"/>
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            <end position="429"/>
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            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
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        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ALN60648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="512" mass="53371" checksum="6C85A8B7EBC6A1D0" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAC8</accession>
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            <fullName evidence="5">Acetyl-coenzyme A synthetase</fullName>
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        </recommendedName>
        <alternativeName>
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        <alternativeName>
            <fullName evidence="5">Acyl-activating enzyme</fullName>
        </alternativeName>
    </protein>
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        <name evidence="5 9" type="primary">acsA</name>
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    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Gammaproteobacteria</taxon>
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            <taxon>Xanthomonadaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
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        <text evidence="5">Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.</text>
    </comment>
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        <reaction evidence="5">
            <text>acetate + ATP + CoA = acetyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23176"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.1"/>
        </reaction>
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    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="5">Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
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        <property type="protein sequence ID" value="ALN55516.1"/>
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    </dbReference>
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        <property type="protein sequence ID" value="QCW24576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
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    <dbReference type="STRING" id="69.GLE_0157"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0003987">
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="ANL_N_sf"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
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        <location>
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    </feature>
    <feature type="region of interest" description="Coenzyme A binding" evidence="5">
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        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>CoA</name>
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        </ligand>
    </feature>
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        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
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        <location>
            <begin position="389"/>
            <end position="391"/>
        </location>
        <ligand>
            <name>ATP</name>
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    </feature>
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        <location>
            <begin position="413"/>
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        </location>
        <ligand>
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        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="502"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="517"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="525"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="528"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="539"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="541"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="544"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="586"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-acetyllysine" evidence="5">
        <location>
            <position position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN55516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW24576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="650" mass="71763" checksum="3AB71CF2D17E864F" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB45</accession>
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        <submittedName>
            <fullName evidence="3">Lytic transglycosylase domain-containing protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">FE772_02415</name>
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        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945950.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55679">
        <property type="protein sequence ID" value="ALN55679"/>
        <property type="gene ID" value="GLE_0321"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0321"/>
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    <dbReference type="OMA" id="WIDKEAT"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SLT" evidence="1">
        <location>
            <begin position="48"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="202" mass="22617" checksum="51BAD3633C82E1DE" modified="2016-02-17" version="1">MTYPKFKKATILKAQGAKLTPKAQTAPVKVAVDPAARLREIRKLVADNNKSDVDDDLIICQIYMESRFVKDPVNQAGSSAKGLMQLLKVAVREIYRVRDLALPKDKRTPEKELYKQADTFHASGALADEATNIAMGTEYLQMLINVQKKKKAADPIAEAYKEYRDKDNGIYYKKISDAAALLKKNPESMQVLLDMVAKAKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBC8</accession>
    <name>A0A0S2DBC8_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Lanthionine synthetase C-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0473</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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        </lineage>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 3">C3</strain>
        </source>
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    <dbReference type="STRING" id="69.GLE_0473"/>
    <dbReference type="EnsemblBacteria" id="ALN55831">
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    <dbReference type="KEGG" id="lez:GLE_0473"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037228">
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    </dbReference>
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        <property type="entry name" value="LANCSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM01260">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03897">
        <property type="entry name" value="lanti_2_LanM"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4135" evidence="1">
        <location>
            <begin position="106"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="958" mass="103162" checksum="0FC99AAE1DB34295" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBI7</accession>
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        <lineage>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
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    <dbReference type="EnsemblBacteria" id="ALN55850">
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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    </dbReference>
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    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="49"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="228" mass="24372" checksum="62BBE75677A360C2" modified="2016-02-17" version="1">MNTPDSAFSDAAAVAGYAERTARLVPGLHDLQRMAALLLAERAPAQARVMVLGAGGGLELKVFAQAQPQWRFDGIDPSAEMLRLARAALGPLAARVAWHEGYVDTAPDGPFDAAACLLTLHFLAEDERRRTVAEVHRRLAPGAPFVVAHHSFPNQGPAMDRWLARNAAFAIANGVAPAQALGGIEAFKQRLPVLPPAVDEAILREAGFADVELFYAGLTFKGWVGYKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBI9</accession>
    <name>A0A0S2DBI9_LYSEN</name>
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        <submittedName>
            <fullName evidence="2">Nucleotidyl transferase family</fullName>
        </submittedName>
    </protein>
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        <name evidence="2" type="ORF">GLE_0542</name>
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    <reference evidence="2 4" key="1">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transf_3" evidence="1">
        <location>
            <begin position="9"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="552" mass="61733" checksum="7BA4B150BF2EFB95" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBJ6</accession>
    <name>A0A0S2DBJ6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Linear gramicidin synthetase subunit D</fullName>
            <ecNumber evidence="6">1.-.-.-</ecNumber>
            <ecNumber evidence="6">5.1.1.-</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Non-ribosomal peptide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FE772_03460</name>
        <name evidence="6" type="ORF">GLE_0546</name>
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        <name type="scientific">Lysobacter enzymogenes</name>
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        <lineage>
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            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.-.-.-" evidence="6"/>
    <dbReference type="EC" id="5.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946115.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0546"/>
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        <property type="protein sequence ID" value="ALN55904"/>
        <property type="gene ID" value="GLE_0546"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0546"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.540"/>
    <dbReference type="OMA" id="MFRPGDD"/>
    <dbReference type="OrthoDB" id="572620at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
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        <property type="entry name" value="SDR_e1"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AA_adenyl_domain"/>
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        <property type="entry name" value="AMP-bd_C"/>
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        <property type="entry name" value="AMP-bd_C_sf"/>
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        <property type="entry name" value="AMP-binding_CS"/>
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        <property type="entry name" value="AMP-dep_Synth/Lig"/>
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        <property type="entry name" value="CAT-like_dom_sf"/>
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        <property type="entry name" value="Far_NAD-bd"/>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
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    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
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        <property type="entry name" value="Thioester_reductase-like_dom"/>
    </dbReference>
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        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07993">
        <property type="entry name" value="NAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01746">
        <property type="entry name" value="Thioester-redct"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 3" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1030"/>
            <end position="1105"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="3">
        <location>
            <position position="1065"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN55904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW24868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="1507" mass="163205" checksum="6B2D12A2DFCF9459" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC62</accession>
    <name>A0A0S2DC62_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0754</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0754"/>
    <dbReference type="EnsemblBacteria" id="ALN56112">
        <property type="protein sequence ID" value="ALN56112"/>
        <property type="gene ID" value="GLE_0754"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0754"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.742"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="128" mass="13286" checksum="DC5441BA4B86DBE5" modified="2016-02-17" version="1">MAALLAQGRTLCAASLLLTAVALVGLFVSDWRAPLWLAAAAGALQLYYAVRVDFDARLLQALAARAETDADAGVARLDAALAALGLRKPGAVARDWPARWRGARALLRKQAGLVILQSAALLAALGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC77</accession>
    <name>A0A0S2DC77_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Redoxin/antioxidant, AhpC/TSA family</fullName>
            <ecNumber evidence="2">1.11.1.15</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="3">TlpA family protein disulfide reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_04530</name>
        <name evidence="2" type="ORF">GLE_0770</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.11.1.15" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0770"/>
    <dbReference type="EnsemblBacteria" id="ALN56128">
        <property type="protein sequence ID" value="ALN56128"/>
        <property type="gene ID" value="GLE_0770"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0770"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.759"/>
    <dbReference type="OMA" id="RKMGRVH"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="61"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="199" mass="21213" checksum="0FC1A756032F5718" modified="2016-02-17" version="1">MAIPSAVKVIAVAVAAGALGLLAGQVVGGGGWFSRTELGQRMLQAEMKMQAPKPPADLAVAERGQPIPRVRLPDLQGRPVELPQAYAGRPLLINLWASWCGPCIKEMPELDRYARSQGEQGVQVIGIALDNRDDVAAFLQRVPVHYPILLDAAGPRDAGVQLGNPKGVLPYSVLVGADGRLLKQRIGPFEDGEIDGWAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC82</accession>
    <name>A0A0S2DC82_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">LysR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator, LysR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_04570</name>
        <name evidence="3" type="ORF">GLE_0775</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946291.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0775"/>
    <dbReference type="EnsemblBacteria" id="ALN56133">
        <property type="protein sequence ID" value="ALN56133"/>
        <property type="gene ID" value="GLE_0775"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0775"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.764"/>
    <dbReference type="OMA" id="AQHSCIY"/>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="331" mass="35803" checksum="DF86CACC66F97BEE" modified="2016-02-17" version="1">MSAGLYSELEAFDAVLRHGSFTAAARQLELTPGAITRRLNALEARLGVKLLNRSTRRLSLTEAGRDYHAEVAPALAQILAAGERARDRAAQPRGELRVSLPMNFGRLYVMPHLGEFLARHPGIELDVQFDDRFVDLIGEGFDCAIRIGALADSRLIARRIAQTRRILVAAPQYLARRGVPTAPAQLSEHDCLHYTLFRGNASWEFHGRGEPLRIPVRGRLRANYGAPLVDAALRGEGILQTATFAVAQELAAGRLVEVLPDWSLLPIGIHAVYPGREYRPRKVEAFVAFLEQIVGAPAVWDRIIVGAAGADAGLADAGFDGAAEAGAATAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCC8</accession>
    <name>A0A0S2DCC8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Polyisoprenoid-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">YceI like family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">BV903_09475</name>
        <name evidence="5" type="ORF">FE772_04660</name>
        <name evidence="3" type="ORF">GLE_0796</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000021">
        <property type="protein sequence ID" value="OPD64110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946303.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0796"/>
    <dbReference type="EnsemblBacteria" id="ALN56154">
        <property type="protein sequence ID" value="ALN56154"/>
        <property type="gene ID" value="GLE_0796"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64110">
        <property type="protein sequence ID" value="OPD64110"/>
        <property type="gene ID" value="BV903_09475"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0796"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.785"/>
    <dbReference type="OMA" id="RFSYSHF"/>
    <dbReference type="OrthoDB" id="1767227at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007372">
        <property type="entry name" value="Lipid/polyisoprenoid-bd_YceI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036761">
        <property type="entry name" value="TTHA0802/YceI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04264">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00867">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101874">
        <property type="entry name" value="SSF101874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594923" evidence="1">
        <location>
            <begin position="21"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="YceI" evidence="2">
        <location>
            <begin position="24"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD64110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="192" mass="20366" checksum="03A25A095C09B22D" modified="2016-02-17" version="1">MKRILLAAALGLAFAGAATAAPVTYKIDPNHTDVIASWSHFGFSNPIAHFGKVDGTITYDQAKPSASSVQVTIPLDGLASHVGDFDEHLKSADFFDAAKYPNITFKSTKVEAAGANKLKVTGDLTVHGVTKPAVLDVNINKIGEQPMAKRAAAGFDATTTLKRSEFGIGKYVPNVSDEVKIRITTEAIVPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCD5</accession>
    <name>A0A0S2DCD5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Phosphomethylpyrimidine synthase</fullName>
            <ecNumber evidence="10">4.1.99.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Hydroxymethylpyrimidine phosphate synthase</fullName>
            <shortName evidence="10">HMP-P synthase</shortName>
            <shortName evidence="10">HMP-phosphate synthase</shortName>
            <shortName evidence="10">HMPP synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Thiamine biosynthesis protein ThiC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 12" type="primary">thiC</name>
        <name evidence="13" type="ORF">BV903_09645</name>
        <name evidence="14" type="ORF">FE772_04845</name>
        <name evidence="12" type="ORF">GLE_0835</name>
    </gene>
    <organism evidence="12 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">C3</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">B25</strain>
        </source>
    </reference>
    <reference evidence="14 17" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + S-adenosyl-L-methionine = 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 5'-deoxyadenosine + CO + formate + 3 H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:24840"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:17245"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58354"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="EC" id="4.1.99.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="10">Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ThiC family.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.17" evidence="10"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000021">
        <property type="protein sequence ID" value="OPD64141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946332.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0835"/>
    <dbReference type="EnsemblBacteria" id="ALN56193">
        <property type="protein sequence ID" value="ALN56193"/>
        <property type="gene ID" value="GLE_0835"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64141">
        <property type="protein sequence ID" value="OPD64141"/>
        <property type="gene ID" value="BV903_09645"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0835"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.824"/>
    <dbReference type="OMA" id="TWELFRD"/>
    <dbReference type="OrthoDB" id="505395at2"/>
    <dbReference type="UniPathway" id="UPA00060"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016830">
        <property type="term" value="F:carbon-carbon lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00089">
        <property type="entry name" value="ThiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037509">
        <property type="entry name" value="ThiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025747">
        <property type="entry name" value="ThiC-associated_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038521">
        <property type="entry name" value="ThiC/Bza_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002817">
        <property type="entry name" value="ThiC/BzaA/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30557">
        <property type="entry name" value="PTHR30557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13667">
        <property type="entry name" value="ThiC-associated"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01964">
        <property type="entry name" value="ThiC_Rad_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00407">
        <property type="entry name" value="phosphomethylpyrimidine_syntha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00190">
        <property type="entry name" value="thiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 10 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 10" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ThiC-associated" evidence="11">
        <location>
            <begin position="22"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="344"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="385"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="424"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="428"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="451"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="492"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="572"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="575"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="580"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN56193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OPD64141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW25098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="625" mass="69546" checksum="182E64A908EADF87" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCE0</accession>
    <name>A0A0S2DCE0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ketol-acid reductoisomerase (NADP(+))</fullName>
            <shortName evidence="11">KARI</shortName>
            <ecNumber evidence="11">1.1.1.86</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Acetohydroxy-acid isomeroreductase</fullName>
            <shortName evidence="11">AHIR</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Alpha-keto-beta-hydroxylacyl reductoisomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 16" type="primary">ilvC</name>
        <name evidence="17" type="ORF">FE772_04790</name>
        <name evidence="16" type="ORF">GLE_0824</name>
    </gene>
    <organism evidence="16 18">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="16 18" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">C3</strain>
        </source>
    </reference>
    <reference evidence="17 19" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 11">Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:22068"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="1.1.1.86"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2-hydroxy-3-oxobutanoate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:13493"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:49256"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.86"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 11">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 11 12">Belongs to the ketol-acid reductoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.86" evidence="11"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946325.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0824"/>
    <dbReference type="EnsemblBacteria" id="ALN56182">
        <property type="protein sequence ID" value="ALN56182"/>
        <property type="gene ID" value="GLE_0824"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0824"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.813"/>
    <dbReference type="OMA" id="RAMFSWL"/>
    <dbReference type="OrthoDB" id="188901at2"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00056"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004455">
        <property type="term" value="F:ketol-acid reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00435">
        <property type="entry name" value="IlvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013023">
        <property type="entry name" value="KARI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000506">
        <property type="entry name" value="KARI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013116">
        <property type="entry name" value="KARI_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014359">
        <property type="entry name" value="KARI_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21371">
        <property type="entry name" value="PTHR21371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01450">
        <property type="entry name" value="IlvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07991">
        <property type="entry name" value="IlvN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000116">
        <property type="entry name" value="IlvC_gammaproteo"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00465">
        <property type="entry name" value="ilvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51851">
        <property type="entry name" value="KARI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51850">
        <property type="entry name" value="KARI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11 12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 11 12" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="16" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8 11 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0521">NADP</keyword>
    <keyword evidence="9 11 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KARI N-terminal Rossmann" evidence="14">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="KARI C-terminal knotted" evidence="15">
        <location>
            <begin position="173"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="322"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="15"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11 12">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11 12">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11 12">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11 12">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11 12">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="ALN56182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="QCW25091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="344" mass="37182" checksum="8461075588F59460" modified="2016-02-17" version="1">MTSTASRPKIAVVGYGSQGRAHALNLRDSGFDVTVGLRPGGPTEIKAKADGFTVKTPAEAVADADLVAVLTPDMVQPQLYRDVIEPNIRQGACLLFAHGFNVHYGQIAPRADLDVVLVAPKGPGALVRREYEIGRGVPSVYAVHQDTSGRAEEFALTYCAGIGGARQNAIKTTFKEETETDLFGEQAVLCGGATKLVQAGWETLVEAGYQPEVAYYECLHELKLIVDLFYEGGITRMHEFISETAQYGALTRGTYVVDDNTRAQMRKVLAEIQDGTFAKQWIAEYASGNANYKALKRGDLEHPIEAVGKKLRANMKWLDNAPKTAAAPAPAPAADRGERQEEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCF4</accession>
    <name>A0A0S2DCF4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0846</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56204">
        <property type="protein sequence ID" value="ALN56204"/>
        <property type="gene ID" value="GLE_0846"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0846"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="52" mass="5910" checksum="9FE3F7DFAE906FB1" modified="2016-02-17" version="1">MRAIDRYGPRLLRHRHSLQAESLEPNPFGQPFAGLASMPVLRRRCGGVKPIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCF8</accession>
    <name>A0A0S2DCF8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Homoserine kinase</fullName>
            <shortName evidence="5">HK</shortName>
            <shortName evidence="5">HSK</shortName>
            <ecNumber evidence="5">2.7.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">thrB</name>
        <name evidence="9" type="ORF">GLE_0828</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + L-homoserine = ADP + H(+) + O-phospho-L-homoserine</text>
            <dbReference type="Rhea" id="RHEA:13985"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57590"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.39"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GHMP kinase family. Homoserine kinase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.39" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946329.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0828"/>
    <dbReference type="EnsemblBacteria" id="ALN56186">
        <property type="protein sequence ID" value="ALN56186"/>
        <property type="gene ID" value="GLE_0828"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0828"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.817"/>
    <dbReference type="OMA" id="CANRIPH"/>
    <dbReference type="OrthoDB" id="610857at2"/>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00064"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004413">
        <property type="term" value="F:homoserine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00384">
        <property type="entry name" value="Homoser_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000870">
        <property type="entry name" value="Homoserine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000676">
        <property type="entry name" value="Homoser_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00191">
        <property type="entry name" value="thrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0791">Threonine biosynthesis</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="7">
        <location>
            <begin position="106"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="8">
        <location>
            <begin position="231"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="113"/>
            <end position="123"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN56186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="329" mass="33751" checksum="5DFCC4141CBBA58E" modified="2016-02-17" version="1">MSAALPSADEADAMPAQHAPPQQARAFAPGSVGNIGVGFDVLGHSIDGVRDVATVRRIDEPSVRIRAIRGAVPGADALPLEAARNTAGQALISLREKLGLAHGFELELDKGIPLGSGLGGSAASCVAALVAANAVLARPLPREALYEFALDGESVSSGSRHGDNVAPMLLGGVVMATATRMIPLAAPDWLYAVVVHPDQVLETRRARAVLAEPYPLAQVVKQSAHLALFLTGLQRGDAGLLREGLVDLLVEPRRAPLIPGFAEVKAAALDHAALGASISGAGPSCFAWFASPADAAAAAIAMRQAFAQAGFDSRAYVTPVAGPRAEVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCH2</accession>
    <name>A0A0S2DCH2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter ATP-binding protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="10">Efflux ABC transporter, permease protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="12">FtsX-like permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">BV903_08460</name>
        <name evidence="12" type="ORF">FE772_04170</name>
        <name evidence="10" type="ORF">GLE_0698</name>
    </gene>
    <organism evidence="10 13">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="10 13" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 13">C3</strain>
        </source>
    </reference>
    <reference evidence="11 14" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 14">B25</strain>
        </source>
    </reference>
    <reference evidence="12 15" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000017">
        <property type="protein sequence ID" value="OPD64442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946226.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000017.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0698"/>
    <dbReference type="EnsemblBacteria" id="ALN56056">
        <property type="protein sequence ID" value="ALN56056"/>
        <property type="gene ID" value="GLE_0698"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64442">
        <property type="protein sequence ID" value="OPD64442"/>
        <property type="gene ID" value="BV903_08460"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0698"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.686"/>
    <dbReference type="OMA" id="YYLDLAW"/>
    <dbReference type="OrthoDB" id="768211at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="23"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="360"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="407"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="9">
        <location>
            <begin position="25"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="346"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="ALN56056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="OPD64442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="QCW24988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="442" mass="48871" checksum="9665265845D5591A" modified="2016-02-17" version="1">MSGNSQFVYYLQLAARSFKRNRVLTALMVVAIALGIGAAMTTLTVFYVLSGDPLPGQSQNLFHPRLEPRSMTGYVPNHEPSDSMTRFDAETLLREARADRQALMTAGNVAIEPRRDNLPAFRQNSRFTSADFFPMFKVPFKYGAAWTGKEDADRARVAVLGKTLNDRLFGGVDSVGKSVWVDNHELRVVGVIESWHPQPNFYDLTLQRGFGEPEDLFVPFSTSRDLRMNPQGNIDCWGDSSALPEGNRSLNAECAWVQYWVELGSAQKADAYRQYLVNYSAQQRAAGRFVRPTAPELDTLMGWLDYKRVVPADVRLQMWLAFGFLAVCLLNTVGLLLAKFLRRSGEIGVRRALGATRRQIFAQCLTEAGSVGLAGGLLGLLLAQLGLWAVRQQQTSYAGLAHLDPTMLAFTFVLAVAASVLAGLLPAWRACQVTPAIQLKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCR4</accession>
    <name>A0A0S2DCR4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Peptidase, M56 family/TonB family C-terminal domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">GLE_0952</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TonB family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946418.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0952"/>
    <dbReference type="EnsemblBacteria" id="ALN56310">
        <property type="protein sequence ID" value="ALN56310"/>
        <property type="gene ID" value="GLE_0952"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0952"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.939"/>
    <dbReference type="OMA" id="PLMHLAW"/>
    <dbReference type="OrthoDB" id="1184688at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008756">
        <property type="entry name" value="Peptidase_M56"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05569">
        <property type="entry name" value="Peptidase_M56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
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    </evidence>
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</entry>
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Displays ATPase and GTPase activities.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RapZ-like family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="GLE_1188"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1188"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1173"/>
    <dbReference type="OMA" id="TVMSFGF"/>
    <dbReference type="Proteomes" id="UP000061569">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005337">
        <property type="entry name" value="RapZ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30448">
        <property type="entry name" value="PTHR30448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03668">
        <property type="entry name" value="ATP_bind_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005052">
        <property type="entry name" value="P-loopkin"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="27"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="79"/>
            <end position="82"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="306" mass="33750" checksum="53F88086D617EA21" modified="2016-02-17" version="1">MSGVESSPAGAHHAAEASGFTLVIVSGMSGSGKSVALNTFEDLGFYCVDNLPAELLPQFVQNVIKAEDGMPTKLAVGIDVRNRHSDLANIPEWLSAVGALGADPRLVFFESSDSVLLKRYADTRRRHPLSQFGLALADAISLERQVLKPLRQIADAIVDTSEFNIHQLRRHVITEFGLGVEAGMSLLFESFAYRRGVPADADFVFDARALPNPHWNPALRPLSGRDAGVRDYLETQADVRLYVEQVGQFLDTWLPRLQGDSTRSYATIAFGCTGGRHRSVYLAERMAEHARLRGWNEVAVHHRELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDH9</accession>
    <name>A0A0S2DDH9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_06885</name>
        <name evidence="1" type="ORF">GLE_1278</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946652.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1278"/>
    <dbReference type="EnsemblBacteria" id="ALN56635">
        <property type="protein sequence ID" value="ALN56635"/>
        <property type="gene ID" value="GLE_1278"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1278"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1261"/>
    <dbReference type="OrthoDB" id="1630944at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW25429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="135" mass="15170" checksum="F41F691D2824074F" modified="2016-02-17" version="1">MTDTAHPRFFWQFPMQLVRHARLDEFLPDDGRLRILFLWGKDCPNCDIAKGQMLLAQERFLWPDVDWLHDNVYEDAAMGTHFGLHGIPAFLVFRGARKLGRIGQWPGTEAFVAAIEKLRADDPASGTAAAPPPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DDK6</accession>
    <name>A0A0S2DDK6_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Dipeptidyl aminopeptidase/acylaminoacyl peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_1034</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="ESTHER" id="lysen-a0a0s2ddk6">
        <property type="family name" value="Glutamyl_Peptidase_S9"/>
    </dbReference>
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        <property type="protein sequence ID" value="ALN56392"/>
        <property type="gene ID" value="GLE_1034"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1034"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1022"/>
    <dbReference type="OMA" id="FPIQSER"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
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        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
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        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595022" evidence="3">
        <location>
            <begin position="45"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="4">
        <location>
            <begin position="691"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="224"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="848"/>
            <end position="874"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN56392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="874" mass="95439" checksum="569D6C08AE00E079" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DE36</accession>
    <name>A0A0S2DE36_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF1611 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_08010</name>
        <name evidence="3" type="ORF">GLE_1529</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946853.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1529"/>
    <dbReference type="EnsemblBacteria" id="ALN56886">
        <property type="protein sequence ID" value="ALN56886"/>
        <property type="gene ID" value="GLE_1529"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1529"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1511"/>
    <dbReference type="OMA" id="LTVGTDM"/>
    <dbReference type="OrthoDB" id="1255116at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035402">
        <property type="entry name" value="DUF1611-N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035086">
        <property type="entry name" value="DUF1611_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011669">
        <property type="entry name" value="UCP026760"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40690">
        <property type="entry name" value="PTHR40690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07755">
        <property type="entry name" value="DUF1611"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17396">
        <property type="entry name" value="DUF1611_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026760">
        <property type="entry name" value="UCP026760"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1611_N" evidence="2">
        <location>
            <begin position="60"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1611" evidence="1">
        <location>
            <begin position="147"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW25618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="353" mass="36980" checksum="19BB8FDD1F698B23" modified="2016-02-17" version="1">MSNPAATPASVAPASLDLPQPYLLFLGDVVHPAFAKTAFGLRDWARERCVGEYALPEAKAGLGLPALTPRQARDAGARALVIGVANVGGVIPDTWLPPLLQALADGLDLIGGMHTRLAEVPMLRDAAARHGRRLIDVREPPAALPTASGRKRSGKRLLTVGTDCALGKKYTALSLARAMREAGIDADFRASGQTGVLIAGRGLPLDAVVADFAAGAAEWLSPDADPAHWDVIEGQGSLSHPAYAGVSLALLHGSQPDAIVVCHEPGRRELLGYPGHAVPSIEETIDLNLRLGRLTNPAIRCAGISFNTSHLSADQAQALMRDESQRLGLPVADPIRGGEALRALVRACVETPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DEB1</accession>
    <name>A0A0S2DEB1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_1323</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
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            <begin position="1"/>
            <end position="28"/>
        </location>
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        <location>
            <begin position="29"/>
            <end position="190"/>
        </location>
    </feature>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="190" mass="20415" checksum="6E25EDBA95EA95EF" modified="2016-02-17" version="1">MMAFAMTRISLVPAFVCRAWAASLPVLAALALPACAASRDSDGKVFVEQQGASICFRVETFKDPSLFAPGAQDVDRERVVARSLEVGRYTEAGYGVAWRAAHPVDEYGQGIRLDRKTRWCYGKAPDGFVATVPAQPLSAGRFRVRIDASNILDPIENSESADFASEFCLADRAGELRLSPCGTAGKPASP</sequence>
</entry>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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    <sequence length="542" mass="56697" checksum="64ED1E859C425E50" modified="2016-02-17" version="1"> </sequence>
</entry>
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    <accession>A0A0S2DEK0</accession>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
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</entry>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2 4">C3</strain>
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        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242128" evidence="1">
        <location>
            <begin position="27"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW25715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="78" mass="8353" checksum="95E04F93EE732471" modified="2016-02-17" version="1">MKIRKMKSKMLALFAVALMGAAGTVAAIPAPGTCTAANQGQQVREYASNGSSRIYLCDANIWQLYAICDTRGRCIVVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DET9</accession>
    <name>A0A0S2DET9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetoacetyl-CoA reductase</fullName>
            <ecNumber evidence="3">1.1.1.36</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Beta-ketoacyl-ACP reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">phbB</name>
        <name evidence="4" type="ORF">BV903_23870</name>
        <name evidence="5" type="ORF">FE772_09270</name>
        <name evidence="3" type="ORF">GLE_1806</name>
    </gene>
    <organism evidence="3 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">C3</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.36" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000087">
        <property type="protein sequence ID" value="OPD61398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW25823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947061.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000087.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1806"/>
    <dbReference type="EnsemblBacteria" id="ALN57158">
        <property type="protein sequence ID" value="ALN57158"/>
        <property type="gene ID" value="GLE_1806"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61398">
        <property type="protein sequence ID" value="OPD61398"/>
        <property type="gene ID" value="BV903_23870"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1806"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1777"/>
    <dbReference type="OMA" id="KLDKAGW"/>
    <dbReference type="OrthoDB" id="1601931at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018454">
        <property type="term" value="F:acetoacetyl-CoA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042619">
        <property type="term" value="P:poly-hydroxybutyrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011283">
        <property type="entry name" value="Acetoacetyl-CoA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01829">
        <property type="entry name" value="AcAcCoA_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="OPD61398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW25823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="246" mass="25946" checksum="F2B9D7435894F5A4" modified="2016-02-17" version="1">MEKRIAVVSGGIGGLGSEICLALARAGRRVIALDLGAREQRIAEFAQLTQGHDIRFEAADVGDFDDCGAAVERIAGRDGGIDILVNAAGITRDGSLRKMDKRAWDEVLNVNLDGVFNLCRHTVDAMAGRGFGRIVNISSVNGQTGQFGQTNYCAAKAGMHGFTMALAREVARKGVTVNSVSPGYCETAMVAAVPEEIRSKIVESVPVGRLGKPSEIARTVEFLTADDAGFITGANIPVNGGLFMSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DF18</accession>
    <name>A0A0S2DF18_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_1823</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_1823"/>
    <dbReference type="EnsemblBacteria" id="ALN57175">
        <property type="protein sequence ID" value="ALN57175"/>
        <property type="gene ID" value="GLE_1823"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_1823"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.1794"/>
    <dbReference type="OMA" id="TGPHLDW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594756" evidence="1">
        <location>
            <begin position="22"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="2">
        <location>
            <begin position="191"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="297" mass="30723" checksum="9434986EE80743E1" modified="2016-02-17" version="1">MRVARCAAALAAAMLAPAASAQVVASGTIPDTAAETAPAAASADARTVFPASVPQGAMVIGKVSPGSVVRYGGRQLRVTPYGSVVFGVGRDAIGPLSVEVQAPGGAPQRAAIAVTPRDFPTEYIQGVPPKTVNPPPEIAARIEREQAQVTAARARDDERPDFAQPFQWPVQGRISGRFGNQRVYNGKKGSGHSGMDIAAPTGTPVKAPAAGVITFAAPDLYLTGGTVLLDHGHGISSNFLHLSRIDAKVGDRIAQGQVIGAVGATGRATGPHLHWGMNWFDVRIDPLLVLERAKTAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFL0</accession>
    <name>A0A0S2DFL0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_10525</name>
        <name evidence="1" type="ORF">GLE_2080</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947262.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57430">
        <property type="protein sequence ID" value="ALN57430"/>
        <property type="gene ID" value="GLE_2080"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2080"/>
    <dbReference type="OrthoDB" id="1903079at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW26038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="188" mass="19835" checksum="55126AD475710FDA" modified="2016-02-17" version="1">MPYKSIQGPLVLSLALIALGAGAIGAPQSKDGLLDLSLSQVVSAASQQARAHDAEQRRADRERFQRALQPRGDAALAPIARELAQLRRFEPLRAGDLVTHSVDGADSTVALRGFVGNGAPLRYSLVQAPRHGRVTIERDRATYRPDPGFAGVDSYTYRVQAGGASAEAMVAVTAIRDRALPATAAAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DFX8</accession>
    <name>A0A0S2DFX8_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta</fullName>
            <shortName evidence="13">ACCase subunit beta</shortName>
            <shortName evidence="13">Acetyl-CoA carboxylase carboxyltransferase subunit beta</shortName>
            <ecNumber evidence="13">2.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13 15" type="primary">accD</name>
        <name evidence="16" type="ORF">BV903_08560</name>
        <name evidence="17" type="ORF">FE772_10850</name>
        <name evidence="15" type="ORF">GLE_2149</name>
    </gene>
    <organism evidence="15 18">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="15 18" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 18">C3</strain>
        </source>
    </reference>
    <reference evidence="16 19" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 19">B25</strain>
        </source>
    </reference>
    <reference evidence="17 20" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 20">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>acetyl-CoA + N(6)-carboxybiotinyl-L-lysyl-[protein] = malonyl-CoA + N(6)-biotinyl-L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:54728"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="EC" id="2.1.3.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="13">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="13">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the AccD/PCCB family.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.15" evidence="13"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000018">
        <property type="protein sequence ID" value="OPD64347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947318.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2149"/>
    <dbReference type="EnsemblBacteria" id="ALN57499">
        <property type="protein sequence ID" value="ALN57499"/>
        <property type="gene ID" value="GLE_2149"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64347">
        <property type="protein sequence ID" value="OPD64347"/>
        <property type="gene ID" value="BV903_08560"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2149"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2113"/>
    <dbReference type="OMA" id="PEGLWIK"/>
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    <sequence length="295" mass="32224" checksum="C61BC8A1B362205E" modified="2016-02-17" version="1">MSWLKKLMPSGIRTETGAAKRRSVPEGLWEKCERCGAVLYRPELEENLEVCPKCSFHMPIRARARLSAFLDAGSGQEIAAELSPVDVLKFKDQKKYSERLKAAQKATGERDSLIAMAGTLKQRPLVAAAMDFAFMGGSMGSVSGERFARGAERAVADGVPMVCFAASGGMRMQESLFSLMQMAKASAALGRMRDAGLPFISVMTHPTFGGTTASFAMLGDLNLAEPGALIGFAGPRVIEQTVREKLPEGFQRSEFLLEHGTVDQICDRREMRDRISHLLAMMMKQPQPEDDVEAA</sequence>
</entry>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    </evidence>
    <sequence length="210" mass="21492" checksum="0EC663A63F297F4D" modified="2016-02-17" version="1">MNRRLFPAVGLLAAAVLAMAACSQSAPVNTAAPQETTAAPPAPPKAVPDPDADPVSRASPPMLTPVALGTFDPGNPVAQATTGKLTIDDLEMKGENGSLYKTERVAIVRGGDQYSAGQTYGATMQVEASQAVELRRVIEQTPPKETPANAFCGTHPTGFIALAKVSEATGDVIKLIALQGSDLPAASAQGVGLCASMFYMGKALPDKATS</sequence>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Feng T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="108"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="134" mass="14159" checksum="F0D18F0C556BFB36" modified="2016-02-17" version="1">MAIAAHPRPAQFLRRVVQADLLVSGAAGLLQLAAAEPLARATAIDADWLRGAGLVLMGWIAFLGWTLARRAIAAPLAWTLIGVNVAWVAASLLVWLQGAIAPNPLGVAFVLAQAAVVAVFAELQYFGLRRQQRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DG69</accession>
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    <protein>
        <submittedName>
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    <organism evidence="1 7">
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    <reference evidence="1 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 7">C3</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="journal article" date="2016" name="DNA Res." volume="0" first="0" last="0">
            <title>Complete genome sequence and expression profile of the commercial lytic enzyme producer, Lysobacter enzymogenes M497-1.</title>
            <authorList>
                <person name="Takami H."/>
                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">M497-1</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="3">
        <citation type="submission" date="2016-10" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="de Groot N.N."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">ATCC 29487</strain>
        </source>
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    <reference evidence="2 10" key="4">
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                <person name="Toyoda A."/>
                <person name="Uchiyama I."/>
                <person name="Itoh T."/>
                <person name="Takaki Y."/>
                <person name="Arai W."/>
                <person name="Nishi S."/>
                <person name="Kawai M."/>
                <person name="Shinya K."/>
                <person name="Ikeda H."/>
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                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
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            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
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            <authorList>
                <person name="Feng T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595100" evidence="1">
        <location>
            <begin position="23"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW26137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="87" mass="9128" checksum="F9D71AF4E4F637C3" modified="2016-02-17" version="1">MKTFPCLALAAALVLASAPALAEVGNLTNTGYGPTKADAEAKAKKNLEEACTSRNGKIVQGSFKVTFDKPLTNGQHYVDATMQCDIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGK3</accession>
    <name>A0A0S2DGK3_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_2352</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57701">
        <property type="protein sequence ID" value="ALN57701"/>
        <property type="gene ID" value="GLE_2352"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2352"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2314"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN57701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="41" mass="4918" checksum="91BA122184B283C5" modified="2016-02-17" version="1">MSRDDKPPSRAFVRKRPSYFLLSARQKKVAKEKRLFKVKSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGN9</accession>
    <name>A0A0S2DGN9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2222</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947374.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN57571">
        <property type="protein sequence ID" value="ALN57571"/>
        <property type="gene ID" value="GLE_2222"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2222"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2187"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN57571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="96" mass="9868" checksum="88966AC8F4E759EE" modified="2016-02-17" version="1">MSAAGAGLAGAVLAGVGLAAAAPPALAWLWSALAVGAVFAAAALAGWRWGARRASRARLAARADRNGRELLRLADEIKAYLAQRQCECAPVLAHRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DGV4</accession>
    <name>A0A0S2DGV4_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Phosphatidylserine decarboxylase proenzyme</fullName>
            <ecNumber evidence="11">4.1.1.65</ecNumber>
        </recommendedName>
        <component>
            <recommendedName>
                <fullName evidence="11">Phosphatidylserine decarboxylase alpha chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="11">Phosphatidylserine decarboxylase beta chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="11 12" type="primary">psd</name>
        <name evidence="13" type="ORF">BV903_08505</name>
        <name evidence="14" type="ORF">FE772_10790</name>
        <name evidence="12" type="ORF">GLE_2137</name>
    </gene>
    <organism evidence="12 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">C3</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">B25</strain>
        </source>
    </reference>
    <reference evidence="14 17" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H(+) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CO2</text>
            <dbReference type="Rhea" id="RHEA:20828"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="EC" id="4.1.1.65"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
        <text evidence="11">Binds 1 pyruvoyl group covalently per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="11">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
            <topology evidence="11">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="11">Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.65" evidence="11"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN57487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000018">
        <property type="protein sequence ID" value="OPD64338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947307.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2137"/>
    <dbReference type="EnsemblBacteria" id="ALN57487">
        <property type="protein sequence ID" value="ALN57487"/>
        <property type="gene ID" value="GLE_2137"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64338">
        <property type="protein sequence ID" value="OPD64338"/>
        <property type="gene ID" value="BV903_08505"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2137"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2101"/>
    <dbReference type="OMA" id="KDYHHYH"/>
    <dbReference type="OrthoDB" id="891720at2"/>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="UniPathway" id="UPA00558">
        <property type="reaction ID" value="UER00616"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004609">
        <property type="term" value="F:phosphatidylserine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00662">
        <property type="entry name" value="PS_decarb_PSD_B_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033177">
        <property type="entry name" value="PSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033178">
        <property type="entry name" value="PSD_type1_pro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067">
        <property type="entry name" value="PTHR10067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00163">
        <property type="entry name" value="PS_decarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 11" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="3 11" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 11 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="10 11" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0865">Zymogen</keyword>
    <feature type="chain" id="PRO_5034831257" description="Phosphatidylserine decarboxylase beta chain" evidence="11">
        <location>
            <begin position="1"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5034831261" description="Phosphatidylserine decarboxylase alpha chain" evidence="11">
        <location>
            <begin position="248"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="11">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="11">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="11">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity" evidence="11">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage (non-hydrolytic); by autocatalysis" evidence="11">
        <location>
            <begin position="247"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="modified residue" description="Pyruvic acid (Ser); by autocatalysis" evidence="11">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN57487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OPD64338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW26083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="282" mass="31008" checksum="C0E29FDBF048FBFD" modified="2016-02-17" version="1">MSLVTTLTYALPHRFLSGLARTLAYSPDPRVSRWLIDTVTEKFGVDLSEAANPDPRAYPTFNAFFTRALKPGARRAQGDARTLLMPADGRISQCGPIRAGEIFQAKGRSFTALELLGGDEAAAAPFRDGDYATVYLSPRDYHRVHMPWTGTLRETVHVPGRLFSVGPDAVRNVPRLFARNERLVCHFDTDFGPMALVMVGALLVSGVETVWSGIEIPAYGDRVTTKDYRGKGIVLKRFEEMARFNYGSTVIVLLPPGVATLDAALQAETAVRLGQPLARRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHP1</accession>
    <name>A0A0S2DHP1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sigma factor regulatory protein, FecR/PupR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_2547</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="69.GLE_2547"/>
    <dbReference type="EnsemblBacteria" id="ALN57896">
        <property type="protein sequence ID" value="ALN57896"/>
        <property type="gene ID" value="GLE_2547"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2547"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2507"/>
    <dbReference type="OMA" id="VLGTQFE"/>
    <dbReference type="OrthoDB" id="1381035at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006860">
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    </dbReference>
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        <property type="entry name" value="FecR_N"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <begin position="20"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="FecR" evidence="1">
        <location>
            <begin position="118"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN57896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="331" mass="35259" checksum="E29AB7321B69AD4A" modified="2016-02-17" version="1">MSQPPAFAIAIADAEPIHAQAREWIAWLASGAADEAGLGEFERWLQRPGHRRAFERERQLWRSLGPRPAAQGTAATWRPRPGRRGRWRPALAAAAVLVLALASPEAWLRLRADHRSAHAAETVALPDGSRAVLDADSAIAIQYDRDQRRVELLRGRVWFEVAADPARRFAVVAGDGVIEDISTAFAVADDAGRIETAVSQGRVRVAATADGGWTYLDAGQRAAYGQGRGVARLNDVPADGIGGWRQGELLLDDAAVDAAVRELARYRAGPILIRGDLGALPKVSAALRIGRPEQALDALAASAGLSVTRLPFGVAIVQPIPTPAPAPAPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DHR9</accession>
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        <submittedName>
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    </protein>
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            <authorList>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
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        <source>
            <dbReference type="EMBL" id="ALN57839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="257" mass="28244" checksum="05D8395808747128" modified="2016-02-17" version="1">MSPAPLTFDRYMREHYDAVPGMSSAFAAHVCAATMRLQRERGWGGDAAEIGAFEGRFLIALALALQPGERALAIDLYDWPDIHVGLRLRERLAGLGLAERVDIICADSRRLAPQRLGGGEGGRAIRFFHIDGDHQPQSLARDMALAFACMAPWGVICLDDMLSPAYPELGIAVAQALQANPQWAVFCVVDREDIAAAAKFLLCRQEYAQAYGEALAREFADRVWGMQAQFARHRALVLAPRPRLTRFNPGGSVDPVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI59</accession>
    <name>A0A0S2DI59_LYSEN</name>
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    <organism evidence="3 4">
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    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
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            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="535"/>
        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="483"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="535" mass="60667" checksum="A0830E83681BE618" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DI62</accession>
    <name>A0A0S2DI62_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    <organism evidence="1 2">
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        <lineage>
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    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58093">
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    </dbReference>
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    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="47" mass="5129" checksum="389F8AB699A7A76B" modified="2016-02-17" version="1">MILTALSDLGAPTRIDVRTNGEALVVLSPRVQVAWLTLHSISYCMDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIF2</accession>
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    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
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    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="ALN58276">
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        <property type="gene ID" value="GLE_2928"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        </location>
    </feature>
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        <location>
            <begin position="23"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW26700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="109" mass="11870" checksum="A6E3422C8E682A36" modified="2016-02-17" version="1">MKLRVAVAPLLALLALSGTASADTLLIQRVQEEGKAALPVRGQSMDQVKARYGEPAQRLDSRGGQKKAWPQINRWVYPAFTVYFEKSRVIDVVANKAGTGEIGPKPPIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIH9</accession>
    <name>A0A0S2DIH9_LYSEN</name>
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        <submittedName>
            <fullName evidence="8">Cytochrome C family protein</fullName>
        </submittedName>
        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">FE772_14665</name>
        <name evidence="8" type="ORF">GLE_2940</name>
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    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Kobayashi D.Y."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2940"/>
    <dbReference type="EnsemblBacteria" id="ALN58288">
        <property type="protein sequence ID" value="ALN58288"/>
        <property type="gene ID" value="GLE_2940"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2940"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2902"/>
    <dbReference type="OMA" id="AYFGARQ"/>
    <dbReference type="OrthoDB" id="1939800at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242191" evidence="6">
        <location>
            <begin position="29"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="7">
        <location>
            <begin position="51"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="26"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="36"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN58288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW26710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="150" mass="15379" checksum="6BA8B2F0A41F88D6" modified="2016-02-17" version="1">MTNPSLLRGLAIASLALALAACSNPGDAPAGHSSADRNEGHTSSSSGLPAGTAAAGEKLANTKGQATGQSCVDCHGAKGNAPIDGLTPKLAGQYHDYIAHSLQMYRDGDREHSLMSSQAKALNDQQIADLAAYFGSIQEGTTLRDLHGIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIN0</accession>
    <name>A0A0S2DIN0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_2917</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947908.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2917"/>
    <dbReference type="EnsemblBacteria" id="ALN58265">
        <property type="protein sequence ID" value="ALN58265"/>
        <property type="gene ID" value="GLE_2917"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2917"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2879"/>
    <dbReference type="OMA" id="GFACFGS"/>
    <dbReference type="OrthoDB" id="1087129at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="29"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="431" mass="48101" checksum="AD9D1CE8847F4987" modified="2016-02-17" version="1">MSILADHYYRASLDADRAWPALEESTRARVCVIGGGFAGLNTALGLAERGVGEVVLLEAQRVGYGASGRNGGFVFGGFSRGEDALLRELGPQRARALYQGTLDAVELIRARIRRYGIDCDATEAGAIWANWFADPEVLRARQRLLAEHFGVEWQWWPRERLRERVRSARYNDALFEPQAFHFHPLKYAQGIAAQAQALGVRVHEGSPALALERDGEGWQVRSERGEVRAEQVVLACGGYLAGLRREVDAAVMPIATYVMVTQPLGELLDGALQTRAAIYDSRFAFDYYRPLRDGRLLWGGRISVRDRSPRQVQRVLYRDLLRVFPQLAGVRIDYAWSGLMSYARHQMPQVGRIGEGLWLAQAFGGHGVAPTTFAGERLAAAIAEGDERWRELSGYGVVSAFKPAGLVAAQASYAWAQFKDWFKDKSERRDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIS5</accession>
    <name>A0A0S2DIS5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DoxX</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">DoxX family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_14830</name>
        <name evidence="7" type="ORF">GLE_2965</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DoxX family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057947944.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_2965"/>
    <dbReference type="EnsemblBacteria" id="ALN58313">
        <property type="protein sequence ID" value="ALN58313"/>
        <property type="gene ID" value="GLE_2965"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_2965"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.2926"/>
    <dbReference type="OMA" id="LWQGYAI"/>
    <dbReference type="OrthoDB" id="2025630at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07681">
        <property type="entry name" value="DoxX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN58313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW26731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="226" mass="24306" checksum="CF60D3920B962AC6" modified="2016-02-17" version="1">MQPSPASTPLFSRIDSVGAWVAPAALRALLAWEFIESGLEKLHGENWFAELGDKFPWPLSLLGADASWFAATWLELIGGAALLLGLGTRYAAFALWVLTVVAIYAVHWPEQWSSLAELWQGYAISDQGHGNYKLPLIYLVMLLPLALGGGGRLSLDHAIARWLRNTSPDAVADGRSWALVALGFGLPSAWLLPWFGGALVALAASLALTALLRRDPSPRNAAALRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DIY0</accession>
    <name>A0A0S2DIY0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Signal recognition particle protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Fifty-four homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">ffh</name>
        <name evidence="10" type="ORF">FE772_16135</name>
        <name evidence="9" type="ORF">GLE_3257</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 11" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">C3</strain>
        </source>
    </reference>
    <reference evidence="10 12" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="7">The SRP-RNC complex is targeted to the cytoplasmic membrane.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the GTP-binding SRP family. SRP54 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948157.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3257"/>
    <dbReference type="EnsemblBacteria" id="ALN58603">
        <property type="protein sequence ID" value="ALN58603"/>
        <property type="gene ID" value="GLE_3257"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3257"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3211"/>
    <dbReference type="OMA" id="DTAGRHK"/>
    <dbReference type="OrthoDB" id="656414at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048500">
        <property type="term" value="C:signal recognition particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00306">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036891">
        <property type="entry name" value="Signal_recog_part_SRP54_M_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004125">
        <property type="entry name" value="Signal_recog_particle_SRP54_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004780">
        <property type="entry name" value="SRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022941">
        <property type="entry name" value="SRP54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564">
        <property type="entry name" value="PTHR11564"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PTHR11564:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SRP54"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF02881">
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    </dbReference>
    <dbReference type="Pfam" id="PF02978">
        <property type="entry name" value="SRP_SPB"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="ffh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="SRP54" evidence="8">
        <location>
            <begin position="269"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="107"/>
            <end position="114"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
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    <feature type="binding site" evidence="7">
        <location>
            <begin position="190"/>
            <end position="194"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
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    <feature type="binding site" evidence="7">
        <location>
            <begin position="248"/>
            <end position="251"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN58603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="QCW26937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="457" mass="49313" checksum="A823651E227580C3" modified="2016-02-17" version="1">MFESLTQRLSGTIERLRGRGRLTEENIREATREVRIALLEADVALPVVQALIERIKVRAVGQEVLKSLTPGQALIKVVRDELTAVMGSQAADLNLNVPAPAVILMAGLQGAGKTTTVGKLAKHLKERRKKKVMVVSADIYRPAAIEQLKQLAEQVDVLFFPSAASQKPEEIVRAAIADARKSFVDVLLVDTAGRLAIDEAMMSEIKALHAAVSPVETLFVVDSMTGQDAATTAKAFSEALPLTGVVLTKTDGDARGGAALSVRYITGKPIKFIGVGEKPDGLDVFHPDRVASRILDMGDVLSLVEQVEQQVDKDKAQKLAEKVAKGKKFDLNDMKDQLEQMQNMGGLSGLMDKLPGMGQIPDNVKSQITGKEVPRMVAIINSMTKKERRNPGLLNGSRRARIAKGAGLTPADVNKLMKQYQQMEKMMSKLSGGGMKGLMRGMRGMMGGGGRGGLPFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJU2</accession>
    <name>A0A0S2DJU2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Multidrug resistance protein, SMR family</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">QacE family quaternary ammonium compound efflux SMR transporter</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="8">Quaternary ammonium compound efflux SMR transporter SugE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">sugE</name>
        <name evidence="7" type="ORF">BV903_20515</name>
        <name evidence="9" type="ORF">D9T17_11600</name>
        <name evidence="8" type="ORF">FE772_16455</name>
        <name evidence="6" type="ORF">GLE_3327</name>
    </gene>
    <organism evidence="6 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 10">C3</strain>
        </source>
    </reference>
    <reference evidence="7 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">OH11</strain>
        </source>
    </reference>
    <reference evidence="8 13" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 13">YC36</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000062">
        <property type="protein sequence ID" value="OPD62067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW26993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000027">
        <property type="protein sequence ID" value="ROU06861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948212.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000027.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3327"/>
    <dbReference type="EnsemblBacteria" id="ALN58673">
        <property type="protein sequence ID" value="ALN58673"/>
        <property type="gene ID" value="GLE_3327"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62067">
        <property type="protein sequence ID" value="OPD62067"/>
        <property type="gene ID" value="BV903_20515"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3327"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3277"/>
    <dbReference type="OMA" id="FEIAWAI"/>
    <dbReference type="OrthoDB" id="1990300at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042221">
        <property type="term" value="P:response to chemical"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000390">
        <property type="entry name" value="Small_drug/metabolite_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045324">
        <property type="entry name" value="Small_multidrug_res"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30561">
        <property type="entry name" value="PTHR30561"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Multi_Drug_Res"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN58673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="OPD62067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW26993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ROU06861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="103" mass="10672" checksum="9ACBDD863EDF6FF0" modified="2016-02-17" version="1">MPWVLLVFAGLFEIGWAIGLKYTEGFTRLWPSVGTVASMAISVGLLGLAMKSLPVGTAYAIWVGIGAVGTVILGMVLFNEPATALRIASIVLIVAGLVGLKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DJX4</accession>
    <name>A0A0S2DJX4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aspartate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_3558</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3558"/>
    <dbReference type="EnsemblBacteria" id="ALN58902">
        <property type="protein sequence ID" value="ALN58902"/>
        <property type="gene ID" value="GLE_3558"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3558"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3502"/>
    <dbReference type="OMA" id="HFDLHYM"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005625">
        <property type="entry name" value="PepSY-ass_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34219">
        <property type="entry name" value="PTHR34219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03929">
        <property type="entry name" value="PepSY_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="440"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="472"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="499"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="532" mass="57549" checksum="41C2759B2383D6C1" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK13</accession>
    <name>A0A0S2DK13_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3546</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3546"/>
    <dbReference type="EnsemblBacteria" id="ALN58890">
        <property type="protein sequence ID" value="ALN58890"/>
        <property type="gene ID" value="GLE_3546"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3546"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3490"/>
    <dbReference type="OMA" id="FTAMKFR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="339" mass="35284" checksum="372F711EA3F08CEC" modified="2016-02-17" version="1">MRHTDSIPTGSLLAGSLAACSITAGSIPARSIPTASNPTDPAAAESPPRAARRILPRLAAWVAAAGLLFGCGAAAAQIPLPVTVAATGNHAEATVRLPFLPGWPGPVVAELLLDFEDASGLSPAALGVSAKTVSLYDPNLIARLPDTDLTTLPGSLPMLVTVQPPLSGGLKFKGSGRVEIHTHWLPYAAGTRLRLFKAPLGGAFYDVTDEIAAGSVRARGTYGGFSQFLILADARPTPLVIASKLQRLRDRVDLLPAAEQPGFDALLDDVETALALATPDYAAALAAADAVRTRAQTRAGTYIDNEWRATRTHRNDAGELAAGAATLRFSVAYLRDYGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK14</accession>
    <name>A0A0S2DK14_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_3490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948328.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3490"/>
    <dbReference type="EnsemblBacteria" id="ALN58835">
        <property type="protein sequence ID" value="ALN58835"/>
        <property type="gene ID" value="GLE_3490"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3490"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3435"/>
    <dbReference type="OrthoDB" id="177497at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN58835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="624" mass="67198" checksum="142501A7DD26EB07" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK35</accession>
    <name>A0A0S2DK35_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aminotransferase class III-fold pyridoxal phosphate-dependent enzyme</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Aminotransferase class-III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_17325</name>
        <name evidence="3" type="ORF">GLE_3522</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948352.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3522"/>
    <dbReference type="EnsemblBacteria" id="ALN58866">
        <property type="protein sequence ID" value="ALN58866"/>
        <property type="gene ID" value="GLE_3522"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3522"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3466"/>
    <dbReference type="OMA" id="APQFKCY"/>
    <dbReference type="OrthoDB" id="1322538at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN58866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="499" mass="53406" checksum="E133A2EC68C9B572" modified="2016-02-17" version="1">MTQLLATLAPLRAHAGKRRTVGLDDETVARFAVTHPELGEAIAAAAAEYALIRELHADLLDLDEDAQIQAIQAGYVNFYPDDGVNPYVALTARGPWVITLKGAVLHDSGGYGMLGFGHTPSAVIAAMAKPQVMANIMTPSLSQLRFERALRGAIGAQRGGCPYERFFCLNSGSESVSLAARIADVNSKLMTDPGARHAGRAIKRLVIKGSFHGRTERPALYSDSSRKAYNQHLASFRGEDSVIAIEPYDAQALKQAFADAEAKGWFIEAMFLEPVMGEGDPGRGVPASFYALARELTRDHGSLLLVDSIQAGLRAHGVLSIVDYPGFEGLDAPDMETYSKALNAGQYPLSVLAVGERAASLYRKGLYGNTMTSNPRALDVAVAVLEQVTPQLQANIRARGAEAIEKLEKLKGELGGLITKVQGTGLLFSCELAPQFKCFGAGSTEEWLRERGIGVIHGGANSLRFTPNFTIASDELELLVSMVGRALREGPRAQQAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK50</accession>
    <name>A0A0S2DK50_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nicotinate-nucleotide diphosphorylase (carboxylating)</fullName>
            <ecNumber evidence="4">2.4.2.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Quinolinate phosphoribosyltransferase [decarboxylating]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">nadC</name>
        <name evidence="14" type="ORF">FE772_17710</name>
        <name evidence="13" type="ORF">GLE_3594</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="13 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 15">C3</strain>
        </source>
    </reference>
    <reference evidence="14 16" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 16">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the catabolism of quinolinic acid (QA).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from quinolinate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the NadC/ModD family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.19" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948405.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3594"/>
    <dbReference type="EnsemblBacteria" id="ALN58938">
        <property type="protein sequence ID" value="ALN58938"/>
        <property type="gene ID" value="GLE_3594"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3594"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3538"/>
    <dbReference type="OMA" id="DMIMLKD"/>
    <dbReference type="OrthoDB" id="1718114at2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00331"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01572">
        <property type="entry name" value="QPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004393">
        <property type="entry name" value="NadC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027277">
        <property type="entry name" value="NadC/ModD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037128">
        <property type="entry name" value="Quinolinate_PRibosylTase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002638">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022412">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32179">
        <property type="entry name" value="PTHR32179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01729">
        <property type="entry name" value="QRPTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02749">
        <property type="entry name" value="QRPTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006250">
        <property type="entry name" value="NadC_ModD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="SSF51690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00078">
        <property type="entry name" value="nadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="QRPTase_N" evidence="12">
        <location>
            <begin position="29"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="QRPTase_C" evidence="11">
        <location>
            <begin position="118"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="138"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="250"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="271"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR006250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006250-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="ALN58938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW27193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="292" mass="30912" checksum="C73755D4520C7441" modified="2016-02-17" version="1">MNAAARDLTPPPAAEIEADVADALAEDLGGGDVTAELLPDSADIAYLLCKEDAVICGRPWFDACHRALDPQVEIDWKVAEGDRVAKGTVLATLRGRSRALVSAERASLNFLQTLSGTATVTAQYVAAVAGTGTRILDTRKTLPGLRLAQKYAVRCGGGVNHRIGLFDAVMLKENHIRAAGSLVAAIRHARERHPGLPLIVEVETLDQLREALTEGCDRILIDDFDAATRREAVRIARAAPFAGRIPLEVSGGVDLDGLRAIAEDGVDCISIGALTKHVRAVDLSLKLGPPPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK66</accession>
    <name>A0A0S2DK66_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Stringent starvation protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">sspA</name>
        <name evidence="4" type="ORF">GLE_3598</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">C3</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily. HSP26 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3598"/>
    <dbReference type="EnsemblBacteria" id="ALN58942">
        <property type="protein sequence ID" value="ALN58942"/>
        <property type="gene ID" value="GLE_3598"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3598"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3542"/>
    <dbReference type="OMA" id="ADHYSHR"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03186">
        <property type="entry name" value="GST_C_SspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03059">
        <property type="entry name" value="GST_N_SspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034342">
        <property type="entry name" value="SspA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034341">
        <property type="entry name" value="SspA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="3"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="86"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN58942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="205" mass="23301" checksum="B3B6C81ED5CAA073" modified="2016-02-17" version="1">MRNALTLFSSTDCVLCHRVRLVLAAKGVTYDLIPVDPQNPPEDLVDLNPYHSVPTLVERDLVLYAASVVSEYLDERYPHPPLMPVDPLSRARLRLAMLRLEHDWVPQVQAIQMGNKVQAEAARKRLKELLTASVPLFKASKFFLNPEMSLADCAMAPIIWRLPSLDVPLPKDAKAIEDYGNRIFRNPGFSRSLTDQERKLRDMPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DK83</accession>
    <name>A0A0S2DK83_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_3614</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58958">
        <property type="protein sequence ID" value="ALN58958"/>
        <property type="gene ID" value="GLE_3614"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3614"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3558"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046116">
        <property type="entry name" value="DUF6053"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19523">
        <property type="entry name" value="DUF6053"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="206" mass="20130" checksum="A1EF6501A200D873" modified="2016-02-17" version="1">MRTALDIAKVPMLVGGLSGPMLRARFAASGSKGVGAEAPPTTAARAASALVRGPSGPMLCAQIAASGSKGIGAEAPPTTAARAASAFVGGPSGPMLCAQFAASGSKGVGAEAPPTTTAQAASVFVGGPSGPMLCAQFAVTRSRGVRAEAPPTTAARVASAFVGGPSGPTLFDPLAANDANRPRAATSSTDTARFLHRNAPRTGRHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKB7</accession>
    <name>A0A0S2DKB7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_24875</name>
        <name evidence="4" type="ORF">FE772_17960</name>
        <name evidence="2" type="ORF">GLE_3652</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000100">
        <property type="protein sequence ID" value="OPD61217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948445.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000100.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN58996">
        <property type="protein sequence ID" value="ALN58996"/>
        <property type="gene ID" value="GLE_3652"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61217">
        <property type="protein sequence ID" value="OPD61217"/>
        <property type="gene ID" value="BV903_24875"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3652"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3596"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595292" evidence="1">
        <location>
            <begin position="22"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD61217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="110" mass="11691" checksum="3F54322F32224123" modified="2016-02-17" version="1">MKTMETICLAFALFVSFGAGAQSIEGPNTPCIGQPTAYKLCLTQNFPYNWGWSVNNGASVVDMGTDGVSCYLATVTPGASAFFLTFSQSNPPGLPQPANITKYAVPRRCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKK3</accession>
    <name>A0A0S2DKK3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L7/L12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">rplL</name>
        <name evidence="8" type="ORF">BV903_21080</name>
        <name evidence="9" type="ORF">FE772_18690</name>
        <name evidence="7" type="ORF">GLE_3798</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL12 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000067">
        <property type="protein sequence ID" value="OPD61935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948562.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000067.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3798"/>
    <dbReference type="EnsemblBacteria" id="ALN59142">
        <property type="protein sequence ID" value="ALN59142"/>
        <property type="gene ID" value="GLE_3798"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61935">
        <property type="protein sequence ID" value="OPD61935"/>
        <property type="gene ID" value="BV903_21080"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3798"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3742"/>
    <dbReference type="OMA" id="LEDKWGV"/>
    <dbReference type="OrthoDB" id="1822695at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00387">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00368">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_L7/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_L7/L12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008932">
        <property type="entry name" value="Ribosomal_L7/L12_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036235">
        <property type="entry name" value="Ribosomal_L7/L12_oligo_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="PTHR45987"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16320">
        <property type="entry name" value="Ribosomal_L12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48300">
        <property type="entry name" value="SSF48300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00855">
        <property type="entry name" value="L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L12_N" evidence="6">
        <location>
            <begin position="5"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L12" evidence="5">
        <location>
            <begin position="57"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD61935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW27369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="123" mass="12819" checksum="26B439329AE59F1E" modified="2016-02-17" version="1">MSLSNEQIVDAIAEKSLMEVMELVRAIEEKFGVSAAAPVVAGVAAEAAAPVEEQTEFTVVLKAAGEKKVEVIKAVRAITGLGLKEAKDLVEGAPQNVKEAVSKDDAAKMKKDLEAAGATVEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKQ8</accession>
    <name>A0A0S2DKQ8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-beta hydroxysteroid dehydrogenase/isomerase family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">NAD-dependent epimerase/dehydratase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_17790</name>
        <name evidence="2" type="ORF">GLE_3613</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN58957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948417.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3613"/>
    <dbReference type="EnsemblBacteria" id="ALN58957">
        <property type="protein sequence ID" value="ALN58957"/>
        <property type="gene ID" value="GLE_3613"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3613"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3557"/>
    <dbReference type="OMA" id="RYPQTTY"/>
    <dbReference type="OrthoDB" id="1928091at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN58957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="339" mass="37007" checksum="3DF7BAF98CAE4754" modified="2016-02-17" version="1">MTAERRIVVTGATGFLGGALARHLAATRPWQQVVGLGRDAGRGRALQAQGVEFHALDLTDEAAVHRVLRGADTVVHCAALSSPWGRREAFVAANITATEHVVAACIARQVRRLVHISTPGIYHDGAPHLGIREDHRLPAKPVNDYAATKLVAERLVFERCAAGGVSALALRPRAIFGPGDSAILPRLAQALRAGRLRRIGDEACMVDLSYIDNVVDATVLAMDASWRLGGRVYNISNGEPVAIWNVIDRLADALSLPRPRKRVPKPLALALASAVEAFHRRFRPDAEPPLLRYGVELLSVDMTLDIARAREELGYRPRVNMDEALDKTLRELARAERRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKS3</accession>
    <name>A0A0S2DKS3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Peptidyl-tRNA hydrolase</fullName>
            <shortName evidence="1">PTH</shortName>
            <ecNumber evidence="1 2">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1 4" type="primary">pth</name>
        <name evidence="5" type="ORF">BV903_21140</name>
        <name evidence="6" type="ORF">FE772_18750</name>
        <name evidence="4" type="ORF">GLE_3807</name>
    </gene>
    <organism evidence="4 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">C3</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">B25</strain>
        </source>
    </reference>
    <reference evidence="6 9" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 9">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = a tRNA + an N-acyl-L-amino acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PTH family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1 2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000067">
        <property type="protein sequence ID" value="OPD61943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948569.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000067.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3807"/>
    <dbReference type="EnsemblBacteria" id="ALN59150">
        <property type="protein sequence ID" value="ALN59150"/>
        <property type="gene ID" value="GLE_3807"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD61943">
        <property type="protein sequence ID" value="OPD61943"/>
        <property type="gene ID" value="BV903_21140"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3807"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3750"/>
    <dbReference type="OMA" id="HVLSKFH"/>
    <dbReference type="OrthoDB" id="1676462at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:aminoacyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00462">
        <property type="entry name" value="PTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00083">
        <property type="entry name" value="Pept_tRNA_hydro_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001328">
        <property type="entry name" value="Pept_tRNA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018171">
        <property type="entry name" value="Pept_tRNA_hydro_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036416">
        <property type="entry name" value="Pept_tRNA_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17224">
        <property type="entry name" value="PTHR17224"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01195">
        <property type="entry name" value="Pept_tRNA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53178">
        <property type="entry name" value="SSF53178"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00447">
        <property type="entry name" value="pth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01195">
        <property type="entry name" value="PEPT_TRNA_HYDROL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN59150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="OPD61943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW27377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="192" mass="21002" checksum="659D897E36C119A0" modified="2016-02-17" version="1">MAGLRLIVGLGNPGAEYTRTRHNAGFWFVDALNEKFGGRFGLESKLFGETSKIEIAGKPVWLLKPATFMNLSGKSVTAALRYWKIEPEEALLAHDELDLAPGTARLKFDGGHGGQNGLRDTIQLLGHGKFHRLRLGIGHPGHKDKVTPWVLGRPGKDDEATILRAIDEAIDVMPLAAQGNFMDAMTRLHTAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DKY3</accession>
    <name>A0A0S2DKY3_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Acylphosphatase</fullName>
            <ecNumber evidence="3 5">3.6.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">acyP</name>
        <name evidence="9" type="ORF">FE772_18850</name>
        <name evidence="8" type="ORF">GLE_3828</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">C3</strain>
        </source>
    </reference>
    <reference evidence="9 11" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 11">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>an acyl phosphate + H2O = a carboxylate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="3.6.1.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the acylphosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.7" evidence="3 5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948583.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_3828"/>
    <dbReference type="EnsemblBacteria" id="ALN59171">
        <property type="protein sequence ID" value="ALN59171"/>
        <property type="gene ID" value="GLE_3828"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_3828"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3770"/>
    <dbReference type="OMA" id="VGFRWSM"/>
    <dbReference type="OrthoDB" id="2034659at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003998">
        <property type="term" value="F:acylphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020456">
        <property type="entry name" value="Acylphosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001792">
        <property type="entry name" value="Acylphosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036046">
        <property type="entry name" value="Acylphosphatase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017968">
        <property type="entry name" value="Acylphosphatase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47268">
        <property type="entry name" value="PTHR47268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00708">
        <property type="entry name" value="Acylphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54975">
        <property type="entry name" value="SSF54975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00150">
        <property type="entry name" value="ACYLPHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51160">
        <property type="entry name" value="ACYLPHOSPHATASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acylphosphatase-like" evidence="7">
        <location>
            <begin position="3"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW27392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="89" mass="9708" checksum="1BE4E3F7DC5A4896" modified="2016-02-17" version="1">MSAARFYIAGKVQGVWFRASAREQALALDLRGYANNLRDGRVEVLAVGDAAAIERLAQWLRQGPPNARVDRIEREPAGENEAGHGFVCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DL86</accession>
    <name>A0A0S2DL86_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Succinate--CoA ligase [ADP-forming] subunit alpha</fullName>
            <ecNumber evidence="2">6.2.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Succinyl-CoA synthetase subunit alpha</fullName>
            <shortName evidence="2">SCS-alpha</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 7" type="primary">sucD</name>
        <name evidence="8" type="ORF">BV903_18450</name>
        <name evidence="9" type="ORF">FE772_20150</name>
        <name evidence="7" type="ORF">GLE_4109</name>
    </gene>
    <organism evidence="7 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 10">C3</strain>
        </source>
    </reference>
    <reference evidence="8 11" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 11">B25</strain>
        </source>
    </reference>
    <reference evidence="9 12" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 12">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 5">
            <text>ATP + CoA + succinate = ADP + phosphate + succinyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 5">Heterotetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the succinate/malate CoA ligase alpha subunit family.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.5" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000050">
        <property type="protein sequence ID" value="OPD62458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948791.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000050.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4109"/>
    <dbReference type="EnsemblBacteria" id="ALN59451">
        <property type="protein sequence ID" value="ALN59451"/>
        <property type="gene ID" value="GLE_4109"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62458">
        <property type="protein sequence ID" value="OPD62458"/>
        <property type="gene ID" value="BV903_18450"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4109"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4051"/>
    <dbReference type="OMA" id="VIICITE"/>
    <dbReference type="OrthoDB" id="1081709at2"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01988">
        <property type="entry name" value="Succ_CoA_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017440">
        <property type="entry name" value="Cit_synth/succinyl-CoA_lig_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033847">
        <property type="entry name" value="Citrt_syn/SCS-alpha_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005810">
        <property type="entry name" value="CoA_lig_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="CoA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001553">
        <property type="entry name" value="SucCS_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01019">
        <property type="entry name" value="sucCoAalpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01216">
        <property type="entry name" value="SUCCINYL_COA_LIG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00399">
        <property type="entry name" value="SUCCINYL_COA_LIG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="1 2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="CoA_binding" evidence="6">
        <location>
            <begin position="4"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Coenzyme A binding" evidence="2">
        <location>
            <begin position="17"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Coenzyme A binding" evidence="2">
        <location>
            <begin position="96"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="2 3">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit beta</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001553-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="OPD62458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="QCW27606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="291" mass="29730" checksum="93C79EEB3D3A51BD" modified="2016-02-17" version="1">MSVLINKNTKVIVQGFTGSQGTFHAEQMLEYGTKVVGGVTPGKGGTQHLGLPVFNTVRDAVEETGADASVIYVPPPFAADAILEAADAGIKVIVCITEGIPVLDMLRVKNTLNGYDDVVLVGPNCPGVITPGECKIGIMPGHIHKPGVIGIVSRSGTLTYEAVKQTTDVGLGQSTCIGIGGDPINGTNFIDALKWFQDDPQTEGIIMVGEIGGSAEEEAAEFIAQYVTKPVVGFIAGASAPKGKRMGHAGAIASGGSGTAEGKFAAMEKAGVTTVKSPGDLGAAIAKRLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLD1</accession>
    <name>A0A0S2DLD1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chromate transporter, chromate ion transporter (CHR) family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">chr</name>
        <name evidence="8" type="ORF">GLE_4016</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4016"/>
    <dbReference type="EnsemblBacteria" id="ALN59358">
        <property type="protein sequence ID" value="ALN59358"/>
        <property type="gene ID" value="GLE_4016"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4016"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3953"/>
    <dbReference type="OMA" id="GMYKNFC"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015109">
        <property type="term" value="F:chromate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014047">
        <property type="entry name" value="Chr_Tranpt_l_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003370">
        <property type="entry name" value="Chromate_transpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02417">
        <property type="entry name" value="Chromate_transp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004810">
        <property type="entry name" value="ChrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00937">
        <property type="entry name" value="2A51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="196"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="299"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="367"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="ALN59358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="401" mass="41709" checksum="A1A8E4BB2438B98F" modified="2016-02-17" version="1">MVEDSHKHDSAWRVFQVFLRLGLTSFGGPIAHLGYFRTEFVERRRWLDEAQFAQLLAVCQFLPGPASSQMGFAIGLFRAGWAGALAAFLAFTLPSALLMFGFATLTPQFDQGMGFAVVHGLKLVAVVVVAHGLLGMVRQLTPDVPRTLLAAGAAALIMLTGSAWAQLAAIALGGVLGPWLCRHVIAPTTAVFPVRYGYGAAGVALATFTAGLMGALLLPADHGPTAPGVAAAFYRAGALVFGGGHVVLPLLQQSLVDTHWVASERFLTGYGAAQAVPGPMFSLSAFLGAQIPVGLPTPVAAAIALLSLFLPGFLLLLAVLPLWARLARRPWAARAMAGVNAVVVGLLAAALYDPLWTQGVRGPVDVAIAAIGLTLMATARCSGLWIVVGCVVATTMASQLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLD5</accession>
    <name>A0A0S2DLD5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4046</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59388">
        <property type="protein sequence ID" value="ALN59388"/>
        <property type="gene ID" value="GLE_4046"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4046"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.3989"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="180" mass="20137" checksum="47DFE8DCDF8D566A" modified="2016-02-17" version="1">MPALAGWLADSWPLAGACSRHRRIDVAPPATGLPGRKASRAAGVGSPTRLLCRDDPTRSRARFKRRRRAPRCRRGEQPHPTRRKCAHASQHPSQRANPSPRNLQASSRATTDEPLESAHAHTRARESKTAAAIVHLSMRAKNFRYAARISCVVRPLENFFIETVDSHHRNNQFFPMATRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLU7</accession>
    <name>A0A0S2DLU7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_20725</name>
        <name evidence="2" type="ORF">GLE_4232</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948888.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59573">
        <property type="protein sequence ID" value="ALN59573"/>
        <property type="gene ID" value="GLE_4232"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4232"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4173"/>
    <dbReference type="OMA" id="KSDYRCQ"/>
    <dbReference type="OrthoDB" id="1485384at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="198" mass="22191" checksum="31E37C453D5A7EF3" modified="2016-02-17" version="1">MKYLKALAATFAFVLVLLAVYAAHVRYGKVDVVLYSAVLDAALAAAIVGGGLFALKAFAEFSRFEKVQMLCLWMLGGYAFAISVPTVIDRSLSFYLLEKIHQRGGGIHVDRLHHVVTQEYMVEHRLIDVRLTEQLQSGTIEVIEDCVRLTERGRGLVGFSRFFRGNLLPRQRLLLGEYSDDLTDPFRNSVADVSYRCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLV1</accession>
    <name>A0A0S2DLV1_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase</fullName>
            <ecNumber evidence="1 2">6.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">D-alanyl-D-alanine-adding enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 5" type="primary">murF</name>
        <name evidence="6" type="ORF">FE772_20265</name>
        <name evidence="5" type="ORF">GLE_4134</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 7" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">C3</strain>
        </source>
    </reference>
    <reference evidence="6 8" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 2">Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>ATP + D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine</text>
            <dbReference type="Rhea" id="RHEA:28374"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:83905"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 2">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MurCDEF family. MurF subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.10" evidence="1 2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948813.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4134"/>
    <dbReference type="EnsemblBacteria" id="ALN59476">
        <property type="protein sequence ID" value="ALN59476"/>
        <property type="gene ID" value="GLE_4134"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4134"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4076"/>
    <dbReference type="OMA" id="VEMGANH"/>
    <dbReference type="OrthoDB" id="1861122at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047480">
        <property type="term" value="F:UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008766">
        <property type="term" value="F:UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02019">
        <property type="entry name" value="MurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005863">
        <property type="entry name" value="UDP-N-AcMur_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="SSF63418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01143">
        <property type="entry name" value="murF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 2" id="KW-0132">Cell division</keyword>
    <keyword evidence="1 2" id="KW-0133">Cell shape</keyword>
    <keyword evidence="1 2" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 2" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="4">
        <location>
            <begin position="112"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="3">
        <location>
            <begin position="325"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="114"/>
            <end position="120"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN59476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="QCW27625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="470" mass="48380" checksum="D3B0CB1C23E7C2FD" modified="2016-02-17" version="1">MKRLSLSEIARLTGGRLRGDDDGRESTIDVVCTDTRALPAQGAALFVALKGERFDGHDHVAGLAHTAVAAALVSREIDAPVAQVIVADTQQALADLAAGVQAQRAGNTVVAITGSNGKTSVKALTAAILERAGKTYATPGNRNNEIGLPLAVLDAPEDARYSIYEMGAGKPGDIAYLVRVARPDVSLVNNIAPAHLERMGSLLGIADTKAAIYDALPDGGAAAINADDAFAPYFEQRVLEQRAAGRRVIRFGLDASAEVTASDVRVGTEGSTFALVTALGRVEIALKLVGRHNVRNALAAAALALGAGVSLQHIADGLNAAQPVDGRLITHRLPNGAVLIDDSYNANPGSTGAAIDTLAEMGGENWLVLGAMREIGDEEIAMHAEIGRRAKAAGLRRLYALGELPAAAAAAFGDGARTFASHDELAAALAAELAAGVRVLVKGSHSSAMDKIVTALLSAHRPGEGTTHVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DLW1</accession>
    <name>A0A0S2DLW1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pyridoxal-phosphate dependent enzyme</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Pyridoxal-phosphate dependent enzyme/CBS domain pair</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">FE772_20815</name>
        <name evidence="7" type="ORF">GLE_4250</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">C3</strain>
        </source>
    </reference>
    <reference evidence="8 10" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 10">YC36</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948904.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4250"/>
    <dbReference type="EnsemblBacteria" id="ALN59591">
        <property type="protein sequence ID" value="ALN59591"/>
        <property type="gene ID" value="GLE_4250"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4250"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4191"/>
    <dbReference type="OMA" id="WMADYGF"/>
    <dbReference type="OrthoDB" id="1677960at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04608">
        <property type="entry name" value="CBS_pair_CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046353">
        <property type="entry name" value="CBS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="6">
        <location>
            <begin position="339"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN59591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="QCW27717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="456" mass="49942" checksum="13AFC41880EC9FDB" modified="2016-02-17" version="1">MAIHNSVLELIGNTPIVKAQRLDTGVCELYLKLESQNPGGSIKDRIGLSMIEAAEKAGKIKPGDTLVEGTAGNTGIGLALVAQQKGYKLLLVVPDKMSREKIFNLKAMGAQVVLTRSDVAKGHPDYYQDLAERIARETPGAYFINQFGNPDNPAAHEFGTGPEILAQMGGPLDAIVFGCGSSGTMTGLSRAFAEHSPNTELVLADPVGSILEEYINRGTLSDKSASWMVEGIGEDFLPPISDFTRVKQAYAISDKESFLTARELLEKEGILGGSSTGTLLAAALKYCREQTAPKKVLVFVCDTGNKYLSKMYNDYWMLDNGFIQRDQHGDLRDLILRPYSQRDTVVVGPNDLLVTAYQRMKLYDVSQLPVMDGEQIVGIVDESDVLLHVYGDESRFRDPVSTAMVSKLDKIQVGEPIESLLPVFDRGHVAIVADGDRFLGLITRIDLLNFLRRRVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM25</accession>
    <name>A0A0S2DM25_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF11 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_21250</name>
        <name evidence="3" type="ORF">GLE_4346</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948980.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4346"/>
    <dbReference type="EnsemblBacteria" id="ALN59687">
        <property type="protein sequence ID" value="ALN59687"/>
        <property type="gene ID" value="GLE_4346"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4346"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4285"/>
    <dbReference type="OrthoDB" id="329384at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01345">
        <property type="entry name" value="DUF11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033726585" evidence="1">
        <location>
            <begin position="37"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="domain" description="DUF11" evidence="2">
        <location>
            <begin position="300"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="DUF11" evidence="2">
        <location>
            <begin position="447"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="688" mass="68610" checksum="07EFD520E0105BDF" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DM81</accession>
    <name>A0A0S2DM81_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Type II secretion system protein H</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">General secretion pathway protein H</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">gspH</name>
        <name evidence="14" type="ORF">GLE_4179</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4179"/>
    <dbReference type="EnsemblBacteria" id="ALN59521">
        <property type="protein sequence ID" value="ALN59521"/>
        <property type="gene ID" value="GLE_4179"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4179"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4121"/>
    <dbReference type="OMA" id="RRWRIDI"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015627">
        <property type="term" value="C:type II protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015628">
        <property type="term" value="P:protein secretion by the type II secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022346">
        <property type="entry name" value="T2SS_GspH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12019">
        <property type="entry name" value="GspH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0488">Methylation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="GspH" evidence="13">
        <location>
            <begin position="71"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF12019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="ALN59521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="178" mass="18560" checksum="776151B68835E857" modified="2016-02-17" version="1">MGGLAPSSPDAPRRGAHPPRARLDGLSPRARQCGMSLLEILLVIALIGAIGVLTVAALSGGVAGMQLRSASKQVAAQLRYTRSQAIASGRSQKFLIDPAAHTWSAPNGRSGEIPKGVGIVFTGARDVQPRRGEGAIVFFPDGASTGGRVKLHAKQAAWNVDVAWLTGEVKLKRGEAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMD5</accession>
    <name>A0A0S2DMD5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase OXA-5</fullName>
            <ecNumber evidence="3">3.5.2.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_21270</name>
        <name evidence="3" type="ORF">GLE_4351</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.5.2.6" evidence="3"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948984.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4351"/>
    <dbReference type="EnsemblBacteria" id="ALN59692">
        <property type="protein sequence ID" value="ALN59692"/>
        <property type="gene ID" value="GLE_4351"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4351"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4290"/>
    <dbReference type="OMA" id="WNRDHTL"/>
    <dbReference type="OrthoDB" id="1688418at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008800">
        <property type="term" value="F:beta-lactamase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033243138" evidence="1">
        <location>
            <begin position="29"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="2">
        <location>
            <begin position="103"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW27797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="276" mass="29546" checksum="36F0E009A0C2934C" modified="2016-02-17" version="1">MNAVRRRFVPRLAVLAALACAVAAPPLAAQYPRSYPTPPASELPQPEQPPLRACFLLSELGGSELRRRPAQGCDRQVSPAATFELAAALAALDASVVRATGASNGQTLESALAYSSPEYFRDIDRQMGATRMGEYLNRFGYGNADTRGGGEYWNGGSLLISPNEQMRFLQRLFGDQLPVSRQSMMSVRESLEPPGYVVSSRGRVIAAAGAMTGGVPPMIKTGAVDAGNESVRWQVGMLTRDNRKYVYVSCVTGPLGLAQNAAEIVASHELRNAGVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DME5</accession>
    <name>A0A0S2DME5_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcriptional repressor NrdR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">nrdR</name>
        <name evidence="13" type="ORF">BV903_07730</name>
        <name evidence="14" type="ORF">FE772_20395</name>
        <name evidence="12" type="ORF">GLE_4159</name>
    </gene>
    <organism evidence="12 15">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="12 15" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 15">C3</strain>
        </source>
    </reference>
    <reference evidence="13 16" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 16">B25</strain>
        </source>
    </reference>
    <reference evidence="14 17" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 17">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the NrdR family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000015">
        <property type="protein sequence ID" value="OPD64542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057948835.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4159"/>
    <dbReference type="EnsemblBacteria" id="ALN59501">
        <property type="protein sequence ID" value="ALN59501"/>
        <property type="gene ID" value="GLE_4159"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64542">
        <property type="protein sequence ID" value="OPD64542"/>
        <property type="gene ID" value="BV903_07730"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4159"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4101"/>
    <dbReference type="OMA" id="YRFTTYE"/>
    <dbReference type="OrthoDB" id="1551627at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00440">
        <property type="entry name" value="NrdR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003796">
        <property type="entry name" value="RNR_NrdR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30455">
        <property type="entry name" value="PTHR30455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00244">
        <property type="entry name" value="TIGR00244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0678">Repressor</keyword>
    <keyword evidence="7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ATP-cone" evidence="11">
        <location>
            <begin position="49"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="zinc finger region" evidence="8">
        <location>
            <begin position="3"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="147"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="ALN59501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="OPD64542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="QCW27646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="172" mass="19816" checksum="D412F15DF70FA4F2" modified="2016-02-17" version="1">MHCPFCQHHDTRVIDSRVSDDGATIRRRRVCEACGERFSTIETIELKLPVIIKGDGRREAFDARKLRAGFDRALQKRPVSEEQIEAAVRAVVHQLRMTAERELASRRVGEFVMAELRKLDHVGYVRFASVYRSFEDVADFREELDRLERDAPGDGQLPLLGGDDPRPDRKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMT7</accession>
    <name>A0A0S2DMT7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YcxB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4487</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949093.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59828">
        <property type="protein sequence ID" value="ALN59828"/>
        <property type="gene ID" value="GLE_4487"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4487"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4424"/>
    <dbReference type="OrthoDB" id="2228806at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025588">
        <property type="entry name" value="YcxB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14317">
        <property type="entry name" value="YcxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="YcxB" evidence="2">
        <location>
            <begin position="98"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="169" mass="18086" checksum="3CE55D99356C581B" modified="2016-02-17" version="1">MPSAQDIRCSFAFTPWERVRLAAVLTFQRKLFLAFALAWPAVGLILAILALAGGVPVGAPLWRMIGLCIVFIPVLLALSAAAGFLVRRGPREPFNYVFDGAGVHVSTSAFAHTHPWSAIVRVKRSQGFVLLFFAPRQAHAIPLRALASPHDEQALVALAQAAGVGAPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMV1</accession>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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        <name evidence="4" type="ORF">D9T17_07030</name>
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    <organism evidence="1 5">
        <name type="scientific">Lysobacter enzymogenes</name>
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        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 5">C3</strain>
        </source>
    </reference>
    <reference evidence="2 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">OH11</strain>
        </source>
    </reference>
    <reference evidence="3 8" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 8">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000006">
        <property type="protein sequence ID" value="OPD65321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW27878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000019">
        <property type="protein sequence ID" value="ROU07944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949066.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4452"/>
    <dbReference type="EnsemblBacteria" id="ALN59793">
        <property type="protein sequence ID" value="ALN59793"/>
        <property type="gene ID" value="GLE_4452"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD65321">
        <property type="protein sequence ID" value="OPD65321"/>
        <property type="gene ID" value="BV903_03230"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4452"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4389"/>
    <dbReference type="OMA" id="QMDALMD"/>
    <dbReference type="OrthoDB" id="1869100at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN59793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="OPD65321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW27878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ROU07944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="120" mass="12042" checksum="002AA29DDED6A845" modified="2016-02-17" version="1">MTPTSTDNVKSNLGQAGGHLKQAAVDAGDAIRSAAGVAGEELKLGKANVKSDLADSALAGIAAAEHAGGAAREQVDALMDKGRDLIESAAELVRERPLASFGVAFAAGFIIAKLARSGDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DMZ4</accession>
    <name>A0A0S2DMZ4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_4416</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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            <taxon>Xanthomonadales</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59757">
        <property type="protein sequence ID" value="ALN59757"/>
        <property type="gene ID" value="GLE_4416"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4416"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN59757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="40" mass="4185" checksum="85B8D336E2362299" modified="2016-02-17" version="1">MRARPGRALDRRGLSDGAAAMRGAARGDAARTCSAPTRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DN13</accession>
    <name>A0A0S2DN13_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membrane/transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4583</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949162.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59924">
        <property type="protein sequence ID" value="ALN59924"/>
        <property type="gene ID" value="GLE_4583"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4583"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4519"/>
    <dbReference type="OMA" id="ALIYIHI"/>
    <dbReference type="OrthoDB" id="1742337at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007349">
        <property type="entry name" value="DUF418"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04235">
        <property type="entry name" value="DUF418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="322"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="DUF418" evidence="2">
        <location>
            <begin position="227"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="396" mass="41898" checksum="46EB5075A6E37E13" modified="2016-02-17" version="1">MHPPVSAVRAARIEHLDALRGLALLGIALVNVGVFASPWWGLGVPDPAFSAPLDRIVAALVATLFEMKFYLLFSFLFGYSFSLQQAAAARAGQAFAPRMGRRLLGLWLIGALHAALLFHGDILTTYALMGALLLGLSRAGETAQLRIAHGLIVATALAWAALGALAWLQPAPAADAAAQAQAVLRGFTGAPAGVLAARADALTSAWPILLALQAPCALAMFLYGHAAGRRSLAARLDDYRPLLRRLRRVGFAVGLPAALALGTIEAWPASEPVQLWVLALSLLTAPLLSLAYAALALPWFAGGGARIADRLAPAGRMALSNYLLQSAAMALLFTGYGLGWMGRISPATTLAIVLTLFAAQLWLSRAWLRRFAYGPVEWLLRAATIGAWPRMGKAAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-06-17" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNG2</accession>
    <name>A0A0S2DNG2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_4630</name>
    </gene>
    <organism evidence="3 4">
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN59971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN59971">
        <property type="protein sequence ID" value="ALN59971"/>
        <property type="gene ID" value="GLE_4630"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4630"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4566"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595445" evidence="2">
        <location>
            <begin position="31"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN59971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="67" mass="6512" checksum="292549F5AB808CC2" modified="2016-02-17" version="1">MAAVALLPSPPRLRAALLCVLAAAPAAATAGVRLDRAAAGAAARTHSSAARRRGGDGRSATAAMFSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DNX7</accession>
    <name>A0A0S2DNX7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutathione S-transferase</fullName>
            <ecNumber evidence="4">2.5.1.18</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Thiol:disulfide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_23995</name>
        <name evidence="4" type="ORF">GLE_4949</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949438.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4949"/>
    <dbReference type="EnsemblBacteria" id="ALN60290">
        <property type="protein sequence ID" value="ALN60290"/>
        <property type="gene ID" value="GLE_4949"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4949"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4877"/>
    <dbReference type="OMA" id="SGSIMQY"/>
    <dbReference type="OrthoDB" id="1560019at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="95"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN60290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW28252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="240" mass="27214" checksum="85C3A4F617C83FFE" modified="2016-02-17" version="1">MIDLHYWPTPNGHKITLFLEEAADAGRPQAYRIEPVNIGAGDQFKPEFLAISPNNRMPAIVDHAPADGGAPISVFESGAILRYLAEKTGLFAPADLRGRVEVDEWLFWQVGGYGPMLGQNHHFNRYAPEKVPYAIDRYQRETERLYGVLDKRLAGREFIAGEALSIADFACYPWAREHDWHHVDLARYPAVQRWHDALSARPAFQRAYEMGKVYRADKAMTDEMRKHLFGTPGSSAPHPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DP03</accession>
    <name>A0A0S2DP03_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_06885</name>
        <name evidence="4" type="ORF">FE772_24005</name>
        <name evidence="2" type="ORF">GLE_4951</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000012">
        <property type="protein sequence ID" value="OPD64750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949440.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000012.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4951"/>
    <dbReference type="EnsemblBacteria" id="ALN60292">
        <property type="protein sequence ID" value="ALN60292"/>
        <property type="gene ID" value="GLE_4951"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64750">
        <property type="protein sequence ID" value="OPD64750"/>
        <property type="gene ID" value="BV903_06885"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4951"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4879"/>
    <dbReference type="OrthoDB" id="2067589at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014807">
        <property type="entry name" value="Coa1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08695">
        <property type="entry name" value="Coa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="140" mass="15694" checksum="FB431BB12AB58870" modified="2016-02-17" version="1">METEYRKPWVQRHWVLMLVLSFVVMMALSLAIGLGSLYALMSSVKDTAPYREAMARVRGDAGMVQALGEPIQTKWIPLGVVEQREQGRAAFVVFLRGPRGEGSVDVQGGFESGTWHYQRLQGEAFGPPRERFDLRSAADH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPD9</accession>
    <name>A0A0S2DPD9_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein-secreting ATPase</fullName>
            <ecNumber evidence="6">7.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">sctN</name>
        <name evidence="9" type="ORF">GLE_5105</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">C3</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.</text>
    </comment>
    <dbReference type="EC" id="7.4.2.8" evidence="6"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5105"/>
    <dbReference type="EnsemblBacteria" id="ALN60446">
        <property type="protein sequence ID" value="ALN60446"/>
        <property type="gene ID" value="GLE_5105"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5105"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5030"/>
    <dbReference type="OMA" id="ICELRTP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030257">
        <property type="term" value="C:type III protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030254">
        <property type="term" value="P:protein secretion by the type III secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005714">
        <property type="entry name" value="ATPase_T3SS_FliI/YscN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040627">
        <property type="entry name" value="T3SS_ATPase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18269">
        <property type="entry name" value="T3SS_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01026">
        <property type="entry name" value="fliI_yscN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA" evidence="8">
        <location>
            <begin position="203"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="13"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="ALN60446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="481" mass="51785" checksum="0290BCF91F5ED3E8" modified="2016-02-17" version="1">MPNTARSTADEPARAAVDGHRRARRDGEARAMSSLPRTVLQPAPAPVQIDPLIAALARVPSVVRVGKVAEAYGTMIRATGLKAMIGELCELRSPRDRSFRLAAEVVGVSRQYTLLTPLGALDGVAHDTEVIATGRQASVRCGEGLLGRILDANGDAIDGRGGFGPTVQMPIYAASPNPLARQLIDRPFATGVRALDTVITAGVGQRLGIFAVAGGGKSTLLGMLARGGDADVNVIALVGERGREVNEFIHDNLGEEGLKKSIIVVATSDRPALERSRAAWVATAIAEYFRDRGKRVMLLVDSVTRFARALRDVGLAIGEPPARRGFPPSVFSQMPRLFERAGNNDKGSITAFYTVLMEGEDGDDPVAEEVRSILDGHIVLSRKLAAAYHYPAIDVLVSLSRTMPRVADEAHQRAAGQLRKYLAKHQDIELLLQLGEYKRGSDADADIAIEKIEPIRKLLKQSSNDLADYKQSIDALRRLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPE2</accession>
    <name>A0A0S2DPE2_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949662.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60587">
        <property type="protein sequence ID" value="ALN60587"/>
        <property type="gene ID" value="GLE_5246"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5246"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5165"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="20"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="177" mass="19594" checksum="DCF5CAC6375BF6E5" modified="2016-02-17" version="1">MNPQLAVTRSEPSLAAPAGLSVRAVTRADAPTLIALCQEHSDRRALERRPYGPPRADALELMEVLFEPPFGAWAWLAEADGEVIGYASATASFSMLERAYCLQLDDPYVREPWLERGVETALLGQALDAARRFGCLNLQCQSPQWSEAARELEAPLRAVRVEAVRYVVRMEDEIAPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2020-12-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPI7</accession>
    <name>A0A0S2DPI7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidoglycan-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5027</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949498.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60368">
        <property type="protein sequence ID" value="ALN60368"/>
        <property type="gene ID" value="GLE_5027"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5027"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4955"/>
    <dbReference type="OMA" id="GPWVRLY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PG_binding_1" evidence="1">
        <location>
            <begin position="24"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="259" mass="27431" checksum="F72FFF33767F84BB" modified="2016-02-17" version="1">MPLQDQSFVRRELDFPGSLRQGASGAAVKRVQEWLGFHGNGTPVDGKFGPGTERALQGFAARKRIAYAGEVGPAVWAALTEPMARVLAAAAPANKPYPQLVRWFAEQHLSVHPIEIGGANRGPWVRLYMKGSEGDSMLWCAGFVSTVLRQAAEHAQRAMPIAGSFGCDELAAQAKAAGRFLAGRTVAGGSPGFAALGACGVFLVRKSASDWVHTGFAFDGNAESFLSIEGNTDHKGSANGFEVAQRARKTAACDFIRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPL7</accession>
    <name>A0A0S2DPL7_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sensor protein QseC</fullName>
            <ecNumber evidence="4">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">FE772_23255</name>
        <name evidence="15" type="ORF">GLE_4779</name>
    </gene>
    <organism evidence="15 17">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="15 17" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 17">C3</strain>
        </source>
    </reference>
    <reference evidence="16 18" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 18">YC36</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="4"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949309.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_4779"/>
    <dbReference type="EnsemblBacteria" id="ALN60120">
        <property type="protein sequence ID" value="ALN60120"/>
        <property type="gene ID" value="GLE_4779"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_4779"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4713"/>
    <dbReference type="OMA" id="NHAMVIH"/>
    <dbReference type="OrthoDB" id="692375at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013727">
        <property type="entry name" value="2CSK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08521">
        <property type="entry name" value="2CSK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="14">
        <location>
            <begin position="194"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="13">
        <location>
            <begin position="253"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="ALN60120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="QCW28132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="469" mass="50367" checksum="E7C6C13FD2DE317A" modified="2016-02-17" version="1">MAEPARAPAGRRDSIRKTLLIYLGALSLIGAALLFLAARSYGRAAADRSYDHLLIASALSIADSVALVDGQWQVDLPYAALDLLAMAPEDRVFYRVSSREGQAITGYADLPAPPSPPRDGQPRLFDAMYRGENTRFVAVSRWVAGPAAQGQAIVQVGQTRRAREALADDMVLRALVAIVALSLAALSLVWIGVYRALRPLQRLERELSERDPSDLRPVAREVPAELDQTVESLNRFMARLAASNETLRAFMGEAAHQMRTPLAALRAQAQLALDEDDPAEQRRSLETIERNASHMSRLLNQLLSDASAIHRSHLQQFETVDLAELLHQAIFEAVPQSGPRPDLHLALTSEALRVRGDALLLREAIKNLIDNALKHGRAPLQIALTAAGEGAAAPTAVLTIADHGPGIAPADAQTVFERFARGRDAAAGGAGLGLAIVKRIVESHGGAIDLSNRVGGGLVVTLRLPRAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPN8</accession>
    <name>A0A0S2DPN8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5207</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60548">
        <property type="protein sequence ID" value="ALN60548"/>
        <property type="gene ID" value="GLE_5207"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5207"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5126"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="37" mass="3984" checksum="3D9C12DC603563DB" modified="2016-02-17" version="1">MWEGLQARCSCTSRCATAQRPTDGLTPAQRSRDTAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DPP8</accession>
    <name>A0A0S2DPP8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_5040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949508.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60381">
        <property type="protein sequence ID" value="ALN60381"/>
        <property type="gene ID" value="GLE_5040"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5040"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.4968"/>
    <dbReference type="OMA" id="ANPRTND"/>
    <dbReference type="OrthoDB" id="735898at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595533" evidence="2">
        <location>
            <begin position="27"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="284" mass="31834" checksum="EB8AF350D6BB44DE" modified="2016-02-17" version="1">MTPPRAPLPWLLAIACLAAAACGSGAAPPPAAEASRPMTPTDANAGERMVEVHLGPHRFRIASNYFDIERGQDAQGFMRLILRWPELAPLPAGTHYLSGGESERARNIDISPDYIDRVPLQTSLERDLISNTDSEQERRENPTLNPDLRIHGDPVHGLTPYYTDFAKVDAYYRARYGKHGDTAAQRHSPFNNDWLVGRDAQGTLTTVIKCTSREEPEGARIVEGRLELLDAPMLPSCSHSFLMPRYGANVRVSYQRIFVRDWKRIEQRIREIFDNGYLGDAPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ20</accession>
    <name>A0A0S2DQ20_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5502</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5502"/>
    <dbReference type="EnsemblBacteria" id="ALN60843">
        <property type="protein sequence ID" value="ALN60843"/>
        <property type="gene ID" value="GLE_5502"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5502"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5417"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="87" mass="9676" checksum="A11D3CD93168D796" modified="2016-02-17" version="1">MADWLRLAGFELRTHTEAGGQFGFKAADGRVAGHADGIIVAGPASFRYPMLWENKAVGTKTFRDCKRNGWPRAVRSTLRRSRSTKPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ24</accession>
    <name>A0A0S2DQ24_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_5251</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60592">
        <property type="protein sequence ID" value="ALN60592"/>
        <property type="gene ID" value="GLE_5251"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5251"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5170"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="41" mass="4836" checksum="CBE5A0B184B283C3" modified="2016-02-17" version="1">MSRDDKPPSTAFVRKRPSYFLLSARQKKVAKEKRLFKVTSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQ57</accession>
    <name>A0A0S2DQ57_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Extracellular phospholipase A1</fullName>
            <ecNumber evidence="2">3.1.1.32</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">phlA</name>
        <name evidence="2" type="ORF">GLE_5168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="3.1.1.32" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949604.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5168"/>
    <dbReference type="EnsemblBacteria" id="ALN60509">
        <property type="protein sequence ID" value="ALN60509"/>
        <property type="gene ID" value="GLE_5168"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5168"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5090"/>
    <dbReference type="OrthoDB" id="1669147at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052740">
        <property type="term" value="F:1-acyl-2-lysophosphatidylserine acylhydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052739">
        <property type="term" value="F:phosphatidylserine 1-acylhydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008970">
        <property type="term" value="F:phospholipase A1 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024499">
        <property type="entry name" value="Mbeg1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11187">
        <property type="entry name" value="DUF2974"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="321" mass="34318" checksum="88EFBE47978FB222" modified="2016-02-17" version="1">MNVQLQPTQLQPTWQKPLEPLAPQLPLNPPVPQGSYALDPSYHPQLAALKGPAANAAPDPTSFDQQLRGQDSQPIDLEMAQISQAVYNPDTQTVGNWTRLDDAQLSQAGIDPGSLENSDTGFRAGIYTDGNGKYVVAYAGSNDVQDWITNARQGIGWDSKQYDQAVQLAQDAQQAFGENMVITGHSLGGGLAATAALATDTAAVTFNASGVHDDTLRGLGLDPSTARNDAADGQIRRYNVSGEILTAAQEDVPILNGIPDAPGHEINLKDPDPPKAPDFTWNPIEMAKRTAEYVADKATRPGELHAIGPVIEALQQQTPWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQA7</accession>
    <name>A0A0S2DQA7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_5409</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949789.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60750">
        <property type="protein sequence ID" value="ALN60750"/>
        <property type="gene ID" value="GLE_5409"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5409"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5324"/>
    <dbReference type="OrthoDB" id="33463at135614"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019690">
        <property type="entry name" value="DUF2569"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10754">
        <property type="entry name" value="DUF2569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="185" mass="19728" checksum="A6428B987CEBE64C" modified="2016-02-17" version="1">MHDEDPYRREPAPPAARGALRLGDEPLRFGTDRSERNRGAVGRGGWLIGVAIMMVWSLLFAMANAGGMAALLASTEVASAMDGAKAGALRFYLAVSAAMFALNLVALVLFAIKSPWFPRVYLAWLGIDLVLVSIATGLLSQASGDGFAGVAAAALVGRVLFWNGPWMAYAVMSERVRNTFAPRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQF5</accession>
    <name>A0A0S2DQF5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fimbrial protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_5457</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5457"/>
    <dbReference type="EnsemblBacteria" id="ALN60798">
        <property type="protein sequence ID" value="ALN60798"/>
        <property type="gene ID" value="GLE_5457"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5457"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5372"/>
    <dbReference type="OMA" id="AYWIPMK"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009289">
        <property type="term" value="C:pilus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1090">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000259">
        <property type="entry name" value="Adhesion_dom_fimbrial"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036937">
        <property type="entry name" value="Adhesion_dom_fimbrial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008966">
        <property type="entry name" value="Adhesion_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00419">
        <property type="entry name" value="Fimbrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49401">
        <property type="entry name" value="SSF49401"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006595433" evidence="1">
        <location>
            <begin position="32"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="Fimbrial" evidence="2">
        <location>
            <begin position="177"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="324" mass="32556" checksum="1B961172AE5E403F" modified="2016-02-17" version="1">MRAERAGRRFPDAAAAAVAACALLAAGAAGAQCAAPAERAIAIDASIAVPRDRPAGSVLYAADYPLPAPAPGCAEAAQDGGWRYAQTPHPSQAEDIYRTGVAAIGVRLSIDGRPLPAAEFAAVAMSPSTRGTLRLELVKLDAGSGGGAIRGADLPTLVYRGGVGAEVGAGDAIAARVNFTGAIAVRAATCNAPSLRIALAPIAPQALAQPGASAGAKDFDLRLDDCPAGLSRISYRLDPLAGADAATSALALDPGASARGVAVQIRDRDGRPVAFGSSHELQAGHLGDGGSFRIPLQAAYYRGDAQPPQPGTVSASLTFTLSYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQL4</accession>
    <name>A0A0S2DQL4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_5432</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949803.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5432"/>
    <dbReference type="EnsemblBacteria" id="ALN60773">
        <property type="protein sequence ID" value="ALN60773"/>
        <property type="gene ID" value="GLE_5432"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5432"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5348"/>
    <dbReference type="OMA" id="TRGMTQY"/>
    <dbReference type="OrthoDB" id="599322at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="Ion_trans_2" evidence="2">
        <location>
            <begin position="48"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN60773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="349" mass="37248" checksum="889A20A553B91E5A" modified="2016-02-17" version="1">MIVLGKLYRSLRGHLRRIGWGVVALALAVHMSASWLLLAAAGEAKLLGWDSFVYYYVTTASTIGYGDLSPGSAAGRWVAALFVMPGAIALFASILAKTSAGLLNFWRRHQVGKMSYEDMRGHTVLIGWHGRESQRLVQLLLADTHTDDEGIVLVAEGVAENPLPDQIRFVAVDSYADCGEYERAALATAARVIVHAADDDRSLAAVFAVMAQKPSAHIVAHFESAAVAQLVRSHYPHVECTRPLHVDVIARAAQDAGSSLVAGEWLGAGGPTQFSLQVPAAAAPVRAGALAAAFRQEAALWIGYRDGRTSAPVLNPPDHVEIAPGTLLYYLADARIDGARLPWASLAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DQM8</accession>
    <name>A0A0S2DQM8_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GntR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator, GntR family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_07970</name>
        <name evidence="5" type="ORF">D9T17_03725</name>
        <name evidence="4" type="ORF">FE772_25160</name>
        <name evidence="2" type="ORF">GLE_5195</name>
    </gene>
    <organism evidence="2 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">C3</strain>
        </source>
    </reference>
    <reference evidence="3 7" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 7">B25</strain>
        </source>
    </reference>
    <reference evidence="5 8" key="3">
        <citation type="submission" date="2018-10" db="EMBL/GenBank/DDBJ databases">
            <title>The genome of Lysobacter enzymogenes OH11.</title>
            <authorList>
                <person name="Liu F."/>
                <person name="Zhao Y."/>
                <person name="Qian G."/>
                <person name="Chen Y."/>
                <person name="Xu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 8">OH11</strain>
        </source>
    </reference>
    <reference evidence="4 9" key="4">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 9">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000016">
        <property type="protein sequence ID" value="OPD64473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW28452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="RCTY01000011">
        <property type="protein sequence ID" value="ROU08596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949624.1">
        <property type="nucleotide sequence ID" value="NZ_RCTY01000011.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5195"/>
    <dbReference type="EnsemblBacteria" id="ALN60536">
        <property type="protein sequence ID" value="ALN60536"/>
        <property type="gene ID" value="GLE_5195"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD64473">
        <property type="protein sequence ID" value="OPD64473"/>
        <property type="gene ID" value="BV903_07970"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5195"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5114"/>
    <dbReference type="OMA" id="FMIETGY"/>
    <dbReference type="OrthoDB" id="1775418at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000275910">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011663">
        <property type="entry name" value="UTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07702">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00866">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="1">
        <location>
            <begin position="18"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN60536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD64473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW28452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ROU08596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000275910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="250" mass="27763" checksum="458E15DDB32AB993" modified="2016-02-17" version="1">MQDYLQSEFRRQSDARRAPAYQHLRRTLQHAIENGELTAGQALPGERELGKLLDLSRVTVRKAIAGLVGDGLLVQRQGAGTFVAERIVKSFSRLTSFTDDLRARGLDPRSTFLERGLGEVTPEEAMALNLSPGAAVIRYYRLRTADGVALALERTVVPAAVIGDPDLVENSLYEAFAKLGIRPTRALQRLRAIAFDAEQARLMNLPEGAPGLFIERRTFLDDGRVVEFTRSFYRGDAYDFVAELQSEPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DR46</accession>
    <name>A0A0S2DR46_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">FE772_00800</name>
        <name evidence="1" type="ORF">GLE_5520</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">C3</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949860.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN60861">
        <property type="protein sequence ID" value="ALN60861"/>
        <property type="gene ID" value="GLE_5520"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5520"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5435"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN60861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="QCW24422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="100" mass="11367" checksum="583E0F0225D2CB60" modified="2016-02-17" version="1">MLKVSARRFRNTAEMLADCGKLMRDLVDGKPTTPLCSEEMKAARDIAQQCHELLWLLCESAWMTMGVEADPKELMAKLWRDDQESPGALMDALWMPHDAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DR87</accession>
    <name>A0A0S2DR87_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alpha/beta hydrolase</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Hydrolase, alpha/beta fold family/TAP-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">FE772_00070</name>
        <name evidence="6" type="ORF">GLE_5355</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">C3</strain>
        </source>
    </reference>
    <reference evidence="7 9" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S33 family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949745.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5355"/>
    <dbReference type="EnsemblBacteria" id="ALN60696">
        <property type="protein sequence ID" value="ALN60696"/>
        <property type="gene ID" value="GLE_5355"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5355"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5270"/>
    <dbReference type="OMA" id="LNCAYWP"/>
    <dbReference type="OrthoDB" id="665798at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013595">
        <property type="entry name" value="Pept_S33_TAP-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002410">
        <property type="entry name" value="Peptidase_S33"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Abhydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00793">
        <property type="entry name" value="PROAMNOPTASE"/>
    </dbReference>
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        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033243150" evidence="3">
        <location>
            <begin position="29"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="107"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Abhydrolase_4" evidence="5">
        <location>
            <begin position="399"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="ALN60696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="QCW24295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="514" mass="54793" checksum="10E5C03E41A609EB" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2007-01-23" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A1EBT6</accession>
    <name>A1EBT6_LYSEN</name>
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        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">GLE_5115</name>
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    <organism evidence="6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
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            <taxon>Gammaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2006-11" db="EMBL/GenBank/DDBJ databases">
            <title>A type III secretion system from the microbial antagonist and biological control bacterium, Lysobacter enzymogenes strain C3.</title>
            <authorList>
                <person name="Reedy R.M."/>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">C3</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">C3</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="EF119743">
        <property type="protein sequence ID" value="ABL59989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057949565.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5115"/>
    <dbReference type="EnsemblBacteria" id="ALN60456">
        <property type="protein sequence ID" value="ALN60456"/>
        <property type="gene ID" value="GLE_5115"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5115"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5040"/>
    <dbReference type="OMA" id="YLAVQME"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HATPase_C"/>
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        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
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        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
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        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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            <end position="373"/>
        </location>
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            <begin position="1"/>
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    <evidence type="ECO:0000256" key="1">
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022553"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="ABL59989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="ALN60456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="376" mass="41368" checksum="59DE39A317AA7E22" modified="2007-01-23" version="1">MARSRSAGSRTVSSTESKPDPKAAAAADPAAAREDAGLLAAVPFACAVFAEDGALRAANARYRAEFGELPEHERREALLARLRGEARDGARPREVRAPHSGRWYALHWGRAEHAGAAADVLTAVDISERMETLASHKSRQEKLLFTSRMMSVGEMAATLAHELNQPLAAIMNYVNGSLRLVEQAGGPVQVERALQAARTQAEHASAVISRVREFVRAREPRRDAHELARIAETVLELLRLEAERLDLRIELGLPDALPPVFADRVMVEQVLLNLVKNAIEAMREIAPERRELRIDARLNLDEQVEVRVCDRGAGLSAAEQDQLFSPFFTTKTDGLGIGLAICRSIIEYHEGRLFFEPREGGGSVFGFTLPRYEARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-01-23" modified="2022-01-19" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A1EBT9</accession>
    <name>A1EBT9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SctD</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Type III secretion apparatus protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">sctD</name>
        <name evidence="5" type="ORF">GLE_5111</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
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            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2006-11" db="EMBL/GenBank/DDBJ databases">
            <title>A type III secretion system from the microbial antagonist and biological control bacterium, Lysobacter enzymogenes strain C3.</title>
            <authorList>
                <person name="Reedy R.M."/>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">C3</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="EF119743">
        <property type="protein sequence ID" value="ABL59992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN60452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_5111"/>
    <dbReference type="EnsemblBacteria" id="ALN60452">
        <property type="protein sequence ID" value="ALN60452"/>
        <property type="gene ID" value="GLE_5111"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_5111"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.5036"/>
    <dbReference type="OrthoDB" id="1151319at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032030">
        <property type="entry name" value="YscD_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16697">
        <property type="entry name" value="Yop-YscD_cpl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Yop-YscD_cpl" evidence="3">
        <location>
            <begin position="46"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="422"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ABL59992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN60452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="478" mass="48541" checksum="389CF7A9A6EFD348" modified="2007-01-23" version="1">MMSHDPHSTPEGAFEAGEPRAAEAPSSPPRAGDGIRAAAPAVSVLRIVSGLHTGGSRPLSAQETVLIGSSGDCDIVLSDPNVAPRHAFLTRMGGTVSLRALDAPLRIEGQTLNPGDPAELGPMQRVDLGGASFAVGAAEDPGWATMLPNLADAVRPAKTSMRHLPLIAGLAALSLVSVAIAAAVMPGFEKKPSPLELAQPLIKEFSIAGGRLSESPDGTLVLSGTVKDAATRETIRKRLASDEVEARLELRTGDDIAADVREVLRSQGLAVQTRYLGNGDVEVSGHFADPAQFQRAIASRAMQDVNGVRRVVPRNLDESHAPAGPAVATAEPAKPAAPVPPTRIVKIVRGDSPHVTDIDGTDYAVGDTLPDGRDLIAIGDKAWALNKTTGVSEQIKAQPLTAEELALASGAAPAADAAATAAAPAGSAPAPAPAAPQAANAAAPSAAKPTTAAPSAAKPSASARPTVAEAPPRPGSRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DA75</accession>
    <name>A0A0S2DA75_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_01320</name>
        <name evidence="2" type="ORF">GLE_0081</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945781.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0081"/>
    <dbReference type="EnsemblBacteria" id="ALN55440">
        <property type="protein sequence ID" value="ALN55440"/>
        <property type="gene ID" value="GLE_0081"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0081"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.86"/>
    <dbReference type="OMA" id="HDEMARC"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021719">
        <property type="entry name" value="Prot_inh_I78"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11720">
        <property type="entry name" value="Inhibitor_I78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242542" evidence="1">
        <location>
            <begin position="25"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="100" mass="10545" checksum="1816E307B8198F9D" modified="2016-02-17" version="1">MSSPISLRLALPVAALGLILSACATPIPPTNVSPTCNAEAARWAIGRAPDAATVDRIRSETRSRDVRVLTPGSAATMDYREDRINVDVNDRGAITGLRCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAH4</accession>
    <name>A0A0S2DAH4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0193</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0193"/>
    <dbReference type="EnsemblBacteria" id="ALN55552">
        <property type="protein sequence ID" value="ALN55552"/>
        <property type="gene ID" value="GLE_0193"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0193"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.195"/>
    <dbReference type="OMA" id="FAEPRVY"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="41"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="439" mass="46656" checksum="8543C28C9D23D9CB" modified="2016-02-17" version="1">MGGISTLVGGTSVPTLSDPVAKHPDASPFDPLHAWMTQATRPGGYLGAVTLIVHEGRIVDFRSYGHRDLARRAPMRRDTIFRIYSMSKTVTSAAVMQLAERGLIDVEAPVQRYLPELADRQVASGDAQAPTLRPARRAITVRHLLTHTAGFAAGLPGDDAATALTRRHDPHAARDLAGFVARLARAPLAADPGTRFGYDGAATEVLARLVEAVSGQRFEAYLREHLFAPLRMRDTGFAVPAAARGRIADLTTTGDDGRLRLDDGPSQREPGAPLNAYASGAGGLYSTACDYARFAQMLLDGGRIADESGFAECDSSRRDGAGPRVLRADTVAAMLRNQLTMLDPPVHQYDAGEGFGYGGAVVIDPARRSVPASLGQFGWPGAASTTYAIDPKRRTVALALLQHLPRAGVAGDPPRLSKDFYRLAFAATDAAGRAAARSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAK7</accession>
    <name>A0A0S2DAK7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase S9</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">S9 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">FE772_01965</name>
        <name evidence="4" type="ORF">GLE_0225</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">C3</strain>
        </source>
    </reference>
    <reference evidence="5 7" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0225"/>
    <dbReference type="EnsemblBacteria" id="ALN55584">
        <property type="protein sequence ID" value="ALN55584"/>
        <property type="gene ID" value="GLE_0225"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0225"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.227"/>
    <dbReference type="OMA" id="TIPPYWE"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242125" evidence="2">
        <location>
            <begin position="29"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="3">
        <location>
            <begin position="442"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="ALN55584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="QCW24625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="691" mass="74451" checksum="1D55A427C14D4B4B" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAL9</accession>
    <name>A0A0S2DAL9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide repeat domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">GLE_0227</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945885.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0227"/>
    <dbReference type="EnsemblBacteria" id="ALN55586">
        <property type="protein sequence ID" value="ALN55586"/>
        <property type="gene ID" value="GLE_0227"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0227"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.229"/>
    <dbReference type="OMA" id="HRGRAYI"/>
    <dbReference type="OrthoDB" id="297722at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030966">
        <property type="entry name" value="Mod_pep_cyc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04510">
        <property type="entry name" value="mod_pep_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="407"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="837"/>
            <end position="880"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="880" mass="96129" checksum="3F541EC2398A686C" modified="2016-02-17" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAN5</accession>
    <name>A0A0S2DAN5_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA/pantothenate metabolism flavoprotein</fullName>
            <ecNumber evidence="2">4.1.1.36</ecNumber>
            <ecNumber evidence="2">6.3.2.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">coaBC</name>
        <name evidence="2" type="ORF">GLE_0252</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="4.1.1.36" evidence="2"/>
    <dbReference type="EC" id="6.3.2.5" evidence="2"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0252"/>
    <dbReference type="EnsemblBacteria" id="ALN55611">
        <property type="protein sequence ID" value="ALN55611"/>
        <property type="gene ID" value="GLE_0252"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0252"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.254"/>
    <dbReference type="OMA" id="AVTDWCP"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004632">
        <property type="term" value="F:phosphopantothenate--cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004633">
        <property type="term" value="F:phosphopantothenoylcysteine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015941">
        <property type="term" value="P:pantothenate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035929">
        <property type="entry name" value="CoaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005252">
        <property type="entry name" value="CoaBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007085">
        <property type="entry name" value="DNA/pantothenate-metab_flavo_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04127">
        <property type="entry name" value="DFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102645">
        <property type="entry name" value="SSF102645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00521">
        <property type="entry name" value="coaBC_dfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DFP" evidence="1">
        <location>
            <begin position="7"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="218" mass="23054" checksum="98F07E18C7447D3D" modified="2016-02-17" version="1">MSAASLGGRRIVVSAGPTYEDIDPVRFIGNRSSGKMGFAIAEAAARRGAQVVLVAGPVSLPTPAGLERVDVRSARQMREAVIAQLPADVYIGAAAVADYAPAEIAPGKIKKKDEQLTLALVRTPDILAEVAVHARRPTVVVGFAAETHDVEFYARGKLEKKKVDMIAANRVGVSGSGFESDDNALTVYWRDGALALGPAPKTELADQLLDLILARWPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAQ0</accession>
    <name>A0A0S2DAQ0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Oxidoreductase</fullName>
            <ecNumber evidence="5">1.1.1.60</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">GLE_0246</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">C3</strain>
        </source>
    </reference>
    <dbReference type="EC" id="1.1.1.60" evidence="5"/>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0246"/>
    <dbReference type="EnsemblBacteria" id="ALN55605">
        <property type="protein sequence ID" value="ALN55605"/>
        <property type="gene ID" value="GLE_0246"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0246"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.248"/>
    <dbReference type="OMA" id="IFVDHTT"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008679">
        <property type="term" value="F:2-hydroxy-3-oxopropionate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016054">
        <property type="term" value="P:organic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="NADP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_binding_2" evidence="3">
        <location>
            <begin position="1"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="NAD_binding_11" evidence="4">
        <location>
            <begin position="157"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000103-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="ALN55605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="288" mass="29610" checksum="2BF11BF5E9D8C801" modified="2016-02-17" version="1">MIGLGAMGAPMARYIHATGGLTAVGNRTQAKADALASELGVRAARSAANFADCDVVVLCVSLDADVLENVAALAEVLKPGAIVVDHSTVSVETARRAAATLGAHDIGFLDAPVSGGVEGARNGKLSIMVGGDAAQFERVQPIVASYAARITHMGGTGAGQATKAINQVLVAGINEAVCEGLALGEKLGLDADKLLPTLMAGAASNWFLDKRGATMLRDEFAPGFKCQHMLKDLRIVQGIARDTGIRTATLDQAAADYAELIERGYGEADTSALIALKRVRAQAESDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAS1</accession>
    <name>A0A0S2DAS1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945749.1">
        <property type="nucleotide sequence ID" value="NZ_CP013140.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55400">
        <property type="protein sequence ID" value="ALN55400"/>
        <property type="gene ID" value="GLE_0041"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0041"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.48"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006594875" evidence="1">
        <location>
            <begin position="24"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="99" mass="10706" checksum="233AA9A0464F7832" modified="2016-02-17" version="1">MSRISKWWLGVASYLLFAMAASAQQPNPYIHVAFDYPAEGAQYVAPANVAIKATATVLDDNVFVTSIVLNGASGQLHQVQGRELTYTLSNCSPATTRCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAV9</accession>
    <name>A0A0S2DAV9_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">FE772_02380</name>
        <name evidence="2" type="ORF">GLE_0313</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">C3</strain>
        </source>
    </reference>
    <reference evidence="3 5" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945946.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN55671">
        <property type="protein sequence ID" value="ALN55671"/>
        <property type="gene ID" value="GLE_0313"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0313"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.310"/>
    <dbReference type="OrthoDB" id="1752426at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="QCW24689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="265" mass="27833" checksum="D9519DB7B5AD4546" modified="2016-02-17" version="1">MSKPALANAHSRLLPPPDRLPLGLWLLSAACAAGWVLCGYSLAGALAQPPDAIAPGAPLQALLWSLLAGGFGGTIFGVFVNAGFGARFGLAVALQASLALAAAALAAGFALARAWPWHPQAALTGLAAGWPQWLFGDAPRSLPAASALIALLLALGALVCLRRYRERSRRIRDLLAHGVRVAGTVVHTEHVGTEVYNPSRVRVVVRFNDHDGAERRVAKIGDFDPRALPRAGERVLVWFYPDAAGDAGRIVVGFGERPQLSQALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DAZ7</accession>
    <name>A0A0S2DAZ7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Complex I NDUFA9 subunit family protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">BV903_20695</name>
        <name evidence="4" type="ORF">FE772_02435</name>
        <name evidence="2" type="ORF">GLE_0325</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">C3</strain>
        </source>
    </reference>
    <reference evidence="3 6" key="2">
        <citation type="submission" date="2017-01" db="EMBL/GenBank/DDBJ databases">
            <title>Draft genome of Lysobacter enzymogenes B25.</title>
            <authorList>
                <person name="Hernandez I."/>
                <person name="Fernandez C."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 6">B25</strain>
        </source>
    </reference>
    <reference evidence="4 7" key="3">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 7">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="MTAY01000063">
        <property type="protein sequence ID" value="OPD62035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945954.1">
        <property type="nucleotide sequence ID" value="NZ_MTAY01000063.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0325"/>
    <dbReference type="EnsemblBacteria" id="ALN55683">
        <property type="protein sequence ID" value="ALN55683"/>
        <property type="gene ID" value="GLE_0325"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="OPD62035">
        <property type="protein sequence ID" value="OPD62035"/>
        <property type="gene ID" value="BV903_20695"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0325"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.322"/>
    <dbReference type="OMA" id="FFNRFAA"/>
    <dbReference type="OrthoDB" id="1928091at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000190203">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="10"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN55683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="OPD62035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000190203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="298" mass="32598" checksum="E180716F1F751AA4" modified="2016-02-17" version="1">MARPHVLVLGGTGFVGRHLVAHLLDQRYRVTVLSRGVDPSKKKKLSRDASIIEGDVANPDFLRAVLDDVDAVVNLVGILNEQGDSGRGFEHVYVELLEALLEAMRDMGVRRLLQMSALNAGTGHSHYLEARGRAEQKVRASKLDWTLFRPSVIAGPGDGLFCRFDALLRYAPMLPIGRAHARFQPVWVGDVTQAFVNALADDAHVQRSYNLVGPDVMTLAEIVRAGARARGRWRAVVPLPDALGKLQAEIGEHLPGKPISRDNWRSLQSDSTSVENGLLKLGVEPTPVLPRLPEILAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB22</accession>
    <name>A0A0S2DB22_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alginate_lyase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_02685</name>
        <name evidence="3" type="ORF">GLE_0379</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057945992.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0379"/>
    <dbReference type="EnsemblBacteria" id="ALN55737">
        <property type="protein sequence ID" value="ALN55737"/>
        <property type="gene ID" value="GLE_0379"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0379"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.376"/>
    <dbReference type="OrthoDB" id="1278416at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008397">
        <property type="entry name" value="Alginate_lyase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008929">
        <property type="entry name" value="Chondroitin_lyas"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05426">
        <property type="entry name" value="Alginate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48230">
        <property type="entry name" value="SSF48230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033243119" description="Alginate_lyase domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="Alginate_lyase" evidence="2">
        <location>
            <begin position="110"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="385" mass="41377" checksum="0B06343A395D801B" modified="2016-02-17" version="1">MPRTTPFRFHALALALLAGAAGSVQAADYSGAAPDATAAAPTAVPPFKHPGLLMTQNRLASIRAAVQSGNSSAMKTGYNRLLQDNRGSHTYAHQALATVEVVRAAGGPQEGRWKNDGFAAYLNALRWAVTGDTRNRDKAVQILDAWSAKFTGFTLAPGTDAPQAWLEAAWGLPVWASAAEILRHHDGGAAGWPQASQDRFNGYLNKLYGYANQASNRTNNWGVSGALAMMATGVYQDDANRYNAGLNRIKQLIPGIVYSSGEVQELAARDCHHPQYSLAGIAQAAEMATIQGDTSVWLLKVGNEPQPRFSRGLEYMAKSILYGEGVRDCRSFGLYPGYSEIAVNGYMNRGTPIPNFQNATKRGRPDGNAAEFIGWSAATHGRDDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DB64</accession>
    <name>A0A0S2DB64_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BPL_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_02895</name>
        <name evidence="3" type="ORF">GLE_0423</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN55781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0423"/>
    <dbReference type="EnsemblBacteria" id="ALN55781">
        <property type="protein sequence ID" value="ALN55781"/>
        <property type="gene ID" value="GLE_0423"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0423"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.420"/>
    <dbReference type="OMA" id="HGGGPNW"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019197">
        <property type="entry name" value="Biotin-prot_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015834">
        <property type="entry name" value="UCP016642"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09825">
        <property type="entry name" value="BPL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016642">
        <property type="entry name" value="UCP016642"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033242265" description="BPL_N domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="BPL_N" evidence="2">
        <location>
            <begin position="40"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN55781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="256" mass="26863" checksum="E1C016CDF79DBAE8" modified="2016-02-17" version="1">MNGLVLKIAACALSGALALPSFAAGRGDASGRADSGTVRVAVYRGPASCENCSETLKRAIERLGPKYRVDFVGADEPIDITARNLASYDVYAQPGGGQDIAGALASLGDERIDAIHDYVARGGRYLGLCMGAYLASGSGLGLIPHELDSEVARPGFAVVDSDDAAVAVRWQGREETVFYQDGPYLLRAAEDPGFKPIATYANGDLAAARYSFGRGVVVLSGPHPEADASWFEAAGIDVARMPDARLLRSLLVELGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBW0</accession>
    <name>A0A0S2DBW0_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0664</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56022">
        <property type="protein sequence ID" value="ALN56022"/>
        <property type="gene ID" value="GLE_0664"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0664"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.653"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="107" mass="12246" checksum="BCEF594493429048" modified="2016-02-17" version="1">MPGKRIEIRFIPEGWRGDPRDAENALSTCGLDFAPLHEDIVKLGYWGAESPLYLREFWSYRKDWPANNITFYLVVNLYRATGGDQPKGRPCVLYIEITADDAEVDHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DBW1</accession>
    <name>A0A0S2DBW1_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="4">LysR family transcriptional regulator</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">FE772_03950</name>
        <name evidence="3" type="ORF">GLE_0649</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">C3</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">YC36</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946188.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0649"/>
    <dbReference type="EnsemblBacteria" id="ALN56007">
        <property type="protein sequence ID" value="ALN56007"/>
        <property type="gene ID" value="GLE_0649"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0649"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.638"/>
    <dbReference type="OMA" id="DLQCFDA"/>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="ALN56007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="QCW24950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="316" mass="34484" checksum="B823CD3875D9D7DD" modified="2016-02-17" version="1">MSGFTLHDLQCFDAVIQAGGFQAAAARLHRSHPAVFAAVARLERQTGLTLLDRSGYRVAATAAGRSFHRRAQSLLAEMQALRSHAEQLAMGEESELHIVLGDLCPRPQALALLGRFFADCAHTRLHLHFESVSGPRERLFDDSADLIVHRAEAGDAQLETIALGEVRMVPVVAPGFLPFPIDRAIRPAQLRGLTQCVMRDSARHSPPVDYFTIDGAPQCTVADQSMKKDLIAHGLAWGHMPHFLVAAELADGRLLSIAGRHLPGRSERLVAARRRDRAHGPVATRLWDHLRAQAPQIRAALASPAGEAAAPRKRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DC04</accession>
    <name>A0A0S2DC04_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">ATP synthase epsilon chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">ATP synthase F1 sector epsilon subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11 13">F-ATPase epsilon subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 17" type="primary">atpC</name>
        <name evidence="18" type="ORF">FE772_04135</name>
        <name evidence="17" type="ORF">GLE_0690</name>
    </gene>
    <organism evidence="17 19">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="17 19" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 19">C3</strain>
        </source>
    </reference>
    <reference evidence="18 20" key="2">
        <citation type="submission" date="2019-05" db="EMBL/GenBank/DDBJ databases">
            <title>Intraspecies Signal LeDSF and Interspecies Signal Indole Synergistically Regulate the Twitching Motility of Lysobacter enzymogenes.</title>
            <authorList>
                <person name="Feng T."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 20">YC36</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 13">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 13 14">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13 14">Belongs to the ATPase epsilon chain family.</text>
    </comment>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CP040656">
        <property type="protein sequence ID" value="QCW24981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_057946219.1">
        <property type="nucleotide sequence ID" value="NZ_CP040656.1"/>
    </dbReference>
    <dbReference type="STRING" id="69.GLE_0690"/>
    <dbReference type="EnsemblBacteria" id="ALN56048">
        <property type="protein sequence ID" value="ALN56048"/>
        <property type="gene ID" value="GLE_0690"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0690"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.678"/>
    <dbReference type="OMA" id="MTIHVDI"/>
    <dbReference type="OrthoDB" id="1696893at2"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000308311">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12152">
        <property type="entry name" value="F1-ATPase_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00530">
        <property type="entry name" value="ATP_synth_epsil_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036794">
        <property type="entry name" value="ATP_F1_dsu/esu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001469">
        <property type="entry name" value="ATP_synth_F1_dsu/esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020547">
        <property type="entry name" value="ATP_synth_F1_dsu/esu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020546">
        <property type="entry name" value="ATP_synth_F1_dsu/esu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036771">
        <property type="entry name" value="ATPsynth_dsu/esu_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13822">
        <property type="entry name" value="PTHR13822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00401">
        <property type="entry name" value="ATP-synt_DE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02823">
        <property type="entry name" value="ATP-synt_DE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46604">
        <property type="entry name" value="SSF46604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51344">
        <property type="entry name" value="SSF51344"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01216">
        <property type="entry name" value="ATP_synt_epsi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13 14" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 13 14" id="KW-0139">CF(1)</keyword>
    <keyword evidence="13" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 13 14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13 14" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP-synt_DE_N" evidence="16">
        <location>
            <begin position="5"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_DE" evidence="15">
        <location>
            <begin position="89"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="ALN56048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="QCW24981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000308311"/>
        </source>
    </evidence>
    <sequence length="141" mass="15091" checksum="57400C0F0C041607" modified="2016-02-17" version="1">MASTFRCDIVSAEDEIFHGEATLLVATGEIGELGIAPRHAPLITRLKPGKVVVTLPSGEQLDFAVSGGILEVQPQVVTVLADTAIRAQDIDEAAVRAAKEEAERALANRGPQMDIAEAQAKLAEAMAQLQALERLRKNMKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCD7</accession>
    <name>A0A0S2DCD7_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">GLE_0777</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56135">
        <property type="protein sequence ID" value="ALN56135"/>
        <property type="gene ID" value="GLE_0777"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0777"/>
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    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046116">
        <property type="entry name" value="DUF6053"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19523">
        <property type="entry name" value="DUF6053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="ALN56135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="42" mass="4173" checksum="574B3AF4AF351226" modified="2016-02-17" version="1">MRRPARCGPSLFRGCGNLGFDAGPLSVGGPSGPMLVAQVAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCI4</accession>
    <name>A0A0S2DCI4_LYSEN</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0877</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobacter antibioticus ATCC 29479.</title>
            <authorList>
                <person name="Kobayashi D.Y."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">C3</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CP013140">
        <property type="protein sequence ID" value="ALN56235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="ALN56235">
        <property type="protein sequence ID" value="ALN56235"/>
        <property type="gene ID" value="GLE_0877"/>
    </dbReference>
    <dbReference type="KEGG" id="lez:GLE_0877"/>
    <dbReference type="PATRIC" id="fig|69.6.peg.866"/>
    <dbReference type="Proteomes" id="UP000061569">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="ALN56235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000061569"/>
        </source>
    </evidence>
    <sequence length="48" mass="4796" checksum="73E03FB186E61048" modified="2016-02-17" version="1">MGAGRVTEVGGGRARAIQGHSGLERTAVSQTQPGADPKRPDPGLGTPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-02-17" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0S2DCJ0</accession>
    <name>A0A0S2DCJ0_LYSEN</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HOASN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">GLE_0891</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Lysobacter enzymogenes</name>
        <dbReference type="NCBI Taxonomy" id="69"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Gammaproteobacteria</taxon>
            <taxon>Xanthomonadales</taxon>
            <taxon>Xanthomonadaceae</taxon>
            <taxon>Lysobacter</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-11" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequences of Lysobacter enzymogenes strain C3 and Lysobact